# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MFS_1 PF07690.11 GAK61808.1 - 1.4e-45 155.5 28.4 1.4e-45 155.5 19.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK61808.1 - 4.6e-12 45.2 7.0 4.6e-12 45.2 4.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAK61808.1 - 2.1e-08 32.8 1.4 3.6e-08 32.0 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 GAK61808.1 - 0.039 11.9 5.5 0.071 11.1 1.6 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 GAK61809.1 - 3.2e-38 131.4 0.0 8.4e-31 106.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 EthD PF07110.6 GAK61810.1 - 5.7e-13 49.6 0.3 8e-13 49.1 0.2 1.2 1 0 0 1 1 1 1 EthD domain Mito_carr PF00153.22 GAK61812.1 - 3.7e-68 225.2 4.7 6.6e-25 86.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Diphtheria_T PF02764.9 GAK61812.1 - 0.048 13.4 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Diphtheria toxin, T domain DUF4243 PF14027.1 GAK61813.1 - 2.6e-63 214.4 3.2 3.6e-63 214.0 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Tyrosinase PF00264.15 GAK61815.1 - 2e-35 122.9 1.9 2.8e-35 122.4 1.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase IBN_N PF03810.14 GAK61817.1 - 9.7e-09 35.0 0.0 4.6e-07 29.6 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 GAK61817.1 - 2.7e-05 22.6 0.1 0.023 12.9 0.0 3.0 2 1 0 2 2 2 2 CAS/CSE protein, C-terminus HEAT PF02985.17 GAK61817.1 - 0.00071 19.4 3.4 1.1 9.5 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat Xpo1 PF08389.7 GAK61817.1 - 0.054 13.4 0.0 4.1 7.3 0.0 3.1 2 1 0 2 2 2 0 Exportin 1-like protein Peptidase_M18 PF02127.10 GAK61818.1 - 4.5e-161 536.1 0.0 5.9e-161 535.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Acyltransferase PF01553.16 GAK61818.1 - 8.5e-20 70.5 0.0 1.9e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Peptidase_M42 PF05343.9 GAK61818.1 - 0.0017 17.2 0.0 0.92 8.2 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase MarR PF01047.17 GAK61818.1 - 0.033 13.9 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 MarR family PCI PF01399.22 GAK61819.1 - 1.5e-20 73.4 0.8 3.6e-20 72.2 0.5 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 GAK61819.1 - 7.4e-11 42.0 0.1 1.4e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_11 PF13414.1 GAK61819.1 - 0.023 14.3 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 TPR repeat MFS_1 PF07690.11 GAK61820.1 - 3.2e-26 91.8 33.3 8.2e-26 90.5 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox PF00070.22 GAK61822.1 - 2.5e-15 56.6 0.1 1.6e-11 44.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAK61822.1 - 2.3e-11 43.9 0.1 0.0042 16.9 0.1 4.3 3 1 1 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK61822.1 - 1e-05 25.6 0.4 0.37 10.8 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAK61822.1 - 0.0085 15.0 0.2 0.36 9.6 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_5 PF12695.2 GAK61822.1 - 0.0087 15.8 0.6 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Trp_halogenase PF04820.9 GAK61822.1 - 0.024 13.2 0.2 2 6.9 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 GAK61822.1 - 0.056 11.9 0.0 9.7 4.5 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 GAK61822.1 - 0.066 12.1 0.0 0.49 9.2 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.12 GAK61822.1 - 0.12 11.4 0.1 5.2 6.0 0.0 2.5 3 0 0 3 3 3 0 Thi4 family GARS_A PF01071.14 GAK61823.1 - 1.6e-71 239.9 0.0 2.3e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 GAK61823.1 - 4.4e-31 107.3 0.0 1.5e-30 105.6 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 GAK61823.1 - 4.4e-31 107.9 0.0 9.7e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 GAK61823.1 - 1.1e-27 96.0 0.2 2.4e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 GAK61823.1 - 7.7e-17 61.3 0.3 3.2e-16 59.3 0.2 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.9 GAK61823.1 - 0.029 14.2 0.0 0.074 12.9 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain Alba PF01918.16 GAK61823.1 - 0.09 12.3 0.1 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Alba Ribosomal_L1 PF00687.16 GAK61824.1 - 2.3e-21 76.1 0.0 1.7e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family DUF3635 PF12330.3 GAK61825.1 - 7.3e-14 51.6 0.1 6.6e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 GAK61825.1 - 0.0012 18.0 0.0 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK61825.1 - 0.0023 17.0 0.0 0.0041 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1682 PF07946.9 GAK61825.1 - 0.019 13.8 1.4 0.032 13.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) 4HBT PF03061.17 GAK61826.1 - 7.9e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 GAK61826.1 - 3.5e-06 26.1 0.0 0.021 13.7 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.1 GAK61826.1 - 1.3e-05 25.6 0.0 2.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily zf-CCCH_2 PF14608.1 GAK61826.1 - 6.7 6.8 5.9 0.98 9.5 0.2 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Abhydrolase_6 PF12697.2 GAK61827.1 - 2.5e-19 70.0 0.0 5.7e-19 68.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK61827.1 - 1.4e-08 34.6 0.1 2.8e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK61827.1 - 0.0019 17.8 0.1 0.027 14.0 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 GAK61827.1 - 0.032 13.7 0.1 0.055 12.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S9 PF00326.16 GAK61827.1 - 0.038 13.1 0.5 0.59 9.3 0.2 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 GAK61827.1 - 0.048 13.5 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase HMG_box PF00505.14 GAK61828.1 - 2e-15 56.8 0.1 6.1e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAK61828.1 - 1.8e-08 34.6 0.1 4.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain Myb_DNA-binding PF00249.26 GAK61828.1 - 2.7e-07 30.5 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRM_1 PF00076.17 GAK61829.1 - 1.3e-12 47.2 0.0 3.3e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK61829.1 - 4.8e-11 42.3 0.0 6.6e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK61829.1 - 6e-10 38.9 0.1 9.2e-05 22.3 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RCC1_2 PF13540.1 GAK61830.1 - 2.5e-14 52.4 13.8 6e-07 28.9 1.6 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 GAK61830.1 - 8.1e-11 41.9 0.1 0.096 12.9 0.0 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat CHD5 PF04420.9 GAK61831.1 - 7.9e-38 129.6 0.3 1.4e-37 128.8 0.2 1.4 1 0 0 1 1 1 1 CHD5-like protein DUF106 PF01956.11 GAK61831.1 - 0.025 14.1 0.5 0.044 13.3 0.1 1.7 1 1 1 2 2 2 0 Integral membrane protein DUF106 Ctr PF04145.10 GAK61831.1 - 0.16 12.0 2.5 2.1 8.3 0.1 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Zip PF02535.17 GAK61832.1 - 1.6e-26 93.0 38.3 1.8e-21 76.5 19.9 3.4 1 1 1 2 2 2 2 ZIP Zinc transporter WD40 PF00400.27 GAK61833.1 - 5.1e-23 80.0 7.1 6.9e-10 38.4 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAK61833.1 - 1.9e-20 72.5 0.1 4.2e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 GAK61833.1 - 0.00014 21.6 0.0 0.0018 18.0 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Raptor_N PF14538.1 GAK61834.1 - 1.4e-61 206.8 0.0 4.3e-61 205.2 0.0 1.9 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 GAK61834.1 - 5.5e-11 41.8 3.0 0.3 11.0 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.17 GAK61834.1 - 6.2e-06 25.8 6.4 0.03 14.4 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat BBS2_Mid PF14783.1 GAK61834.1 - 6.2e-06 25.9 0.0 0.0028 17.4 0.0 2.8 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 GAK61834.1 - 0.57 10.5 4.8 1.1 9.5 0.1 3.6 3 1 1 4 4 4 0 HEAT repeats Sugar_tr PF00083.19 GAK61835.1 - 9e-12 44.2 0.3 1.4e-11 43.6 0.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK61835.1 - 4e-05 22.4 1.2 4e-05 22.4 0.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3435 PF11917.3 GAK61836.1 - 0.00033 19.5 0.0 0.00078 18.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) CAP_N PF01213.14 GAK61836.1 - 0.46 9.7 3.7 1.1 8.5 2.6 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sugar_tr PF00083.19 GAK61837.1 - 2.4e-07 29.6 4.9 3.3e-07 29.2 3.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Cupin_8 PF13621.1 GAK61838.1 - 2.4e-13 50.1 0.0 1.1e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 GAK61838.1 - 1.5e-08 34.8 0.0 1e-07 32.2 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 GAK61838.1 - 0.00061 19.1 0.0 0.0019 17.5 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.6 GAK61838.1 - 0.15 11.6 0.0 0.69 9.4 0.0 2.0 2 0 0 2 2 2 0 Cupin domain F-box-like PF12937.2 GAK61838.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 F-box-like SNF2_N PF00176.18 GAK61839.1 - 2e-65 220.5 0.0 2.6e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 GAK61839.1 - 1.8e-29 101.7 0.0 3.3e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 GAK61839.1 - 6.6e-12 45.1 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 GAK61839.1 - 3.8e-05 23.4 12.2 6.4e-05 22.6 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAK61839.1 - 4.1e-05 23.2 11.8 7.1e-05 22.4 8.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAK61839.1 - 0.00022 21.1 13.0 0.00038 20.4 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK61839.1 - 0.0069 16.0 13.0 0.012 15.2 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PfkB PF00294.19 GAK61840.1 - 4e-60 203.5 4.4 4.6e-60 203.2 3.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 GAK61840.1 - 1.5e-05 24.3 0.0 3.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HAD_2 PF13419.1 GAK61840.1 - 0.1 12.8 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TMF_DNA_bd PF12329.3 GAK61841.1 - 0.00057 19.6 10.7 0.00057 19.6 7.4 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding EzrA PF06160.7 GAK61841.1 - 0.013 13.7 3.1 0.015 13.4 2.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APG6 PF04111.7 GAK61841.1 - 0.047 12.7 4.1 0.05 12.6 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 GAK61841.1 - 0.05 13.5 5.3 0.067 13.1 3.1 1.7 1 1 0 1 1 1 0 FlxA-like protein TBPIP PF07106.8 GAK61841.1 - 0.052 13.0 6.6 0.052 13.0 3.7 1.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF904 PF06005.7 GAK61841.1 - 0.069 13.4 5.4 0.12 12.6 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Tup_N PF08581.5 GAK61841.1 - 0.072 13.2 0.3 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Tup N-terminal FlaC_arch PF05377.6 GAK61841.1 - 0.1 12.5 1.3 0.9 9.4 0.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 GAK61841.1 - 0.11 12.2 7.2 0.15 11.8 5.0 1.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Vps51 PF08700.6 GAK61841.1 - 0.13 12.1 2.2 0.42 10.4 0.2 2.1 1 1 1 2 2 2 0 Vps51/Vps67 YlqD PF11068.3 GAK61841.1 - 0.42 10.6 7.0 5.9 6.9 3.2 2.1 1 1 1 2 2 2 0 YlqD protein DUF972 PF06156.8 GAK61841.1 - 0.66 10.3 2.8 1.1 9.6 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 GAK61841.1 - 0.88 9.3 9.4 1.2 8.8 6.5 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 GAK61841.1 - 0.94 8.3 6.9 1.2 8.0 4.7 1.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 GAK61841.1 - 1.5 8.3 8.8 1.4 8.4 1.3 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF3373 PF11853.3 GAK61841.1 - 1.6 7.2 4.3 2 6.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4140 PF13600.1 GAK61841.1 - 1.8 9.0 5.5 1.4 9.4 2.1 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SKN1 PF03935.10 GAK61842.1 - 1.6e-188 626.9 4.4 2e-188 626.6 3.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 GAK61842.1 - 0.0038 16.6 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Neurensin Peptidase_M1 PF01433.15 GAK61848.1 - 4e-108 361.9 1.4 1.4e-68 231.7 0.1 2.2 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 GAK61848.1 - 1e-61 209.0 0.9 1.9e-61 208.1 0.6 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAK61848.1 - 4.1e-14 52.7 0.0 9.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily AMP-binding PF00501.23 GAK61849.1 - 9.2e-47 159.3 0.0 1.4e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAK61849.1 - 1.3e-12 47.7 0.6 2.9e-12 46.6 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 GAK61849.1 - 2.6e-11 42.4 3.5 0.00037 19.8 0.0 7.2 8 0 0 8 8 8 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.1 GAK61849.1 - 2.6e-09 37.8 2.3 3.7e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 GAK61849.1 - 0.038 13.5 10.0 7.6 6.1 0.2 5.3 5 1 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 GAK61849.1 - 0.78 8.1 0.0 14 4.0 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Carn_acyltransf PF00755.15 GAK61850.1 - 6.7e-171 569.3 0.0 8.3e-171 569.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Chorion_2 PF03964.10 GAK61850.1 - 6.2 7.4 8.5 0.18 12.3 0.2 2.6 2 0 0 2 2 2 0 Chorion family 2 MMR_HSR1 PF01926.18 GAK61851.1 - 6.3e-11 42.2 0.0 3.6e-10 39.8 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 GAK61851.1 - 0.038 13.9 0.1 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 GAK61851.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 GAK61851.1 - 0.082 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lyase_1 PF00206.15 GAK61852.1 - 8.7e-117 389.7 0.0 1.3e-116 389.2 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 GAK61852.1 - 3.9e-20 71.6 1.0 1.5e-18 66.5 0.1 2.6 2 0 0 2 2 2 1 Fumarase C C-terminus Ima1_N PF09779.4 GAK61853.1 - 3.7e-17 63.0 4.6 3.7e-17 63.0 3.2 2.5 2 1 0 2 2 2 1 Ima1 N-terminal domain Rsm22 PF09243.5 GAK61854.1 - 1.2e-31 109.7 0.6 1.9e-14 53.4 0.0 4.8 3 2 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.1 GAK61854.1 - 0.13 11.8 0.0 7.2 6.1 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain DUF2414 PF10309.4 GAK61855.1 - 2.1e-05 24.1 0.0 8e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 GAK61855.1 - 0.00091 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain RRM_6 PF14259.1 GAK61855.1 - 0.052 13.5 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAK61855.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Bin3 PF06859.7 GAK61856.1 - 2.8e-24 85.2 0.0 4.5e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 GAK61856.1 - 5.4e-11 43.0 0.0 1.4e-09 38.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK61856.1 - 3.1e-10 40.0 0.0 7.8e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK61856.1 - 8.2e-10 38.4 0.0 9.1e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK61856.1 - 2.3e-09 37.6 0.0 1.6e-06 28.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK61856.1 - 2.8e-06 27.7 0.0 0.019 15.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain CheR PF01739.13 GAK61856.1 - 0.00012 21.4 0.0 0.002 17.4 0.0 2.1 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 GAK61856.1 - 0.00045 20.2 0.7 0.0014 18.6 0.5 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK61856.1 - 0.00075 19.8 0.0 0.061 13.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAK61856.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAK61856.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 GAK61856.1 - 0.033 14.9 0.0 0.088 13.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Heme_oxygenase PF01126.15 GAK61857.1 - 1.5e-25 90.0 0.3 1.7e-21 76.7 0.0 2.9 2 1 0 2 2 2 2 Heme oxygenase PH PF00169.24 GAK61858.1 - 0.00036 20.6 0.0 0.0049 17.0 0.0 2.6 2 1 0 2 2 2 1 PH domain BBS2_C PF14782.1 GAK61858.1 - 0.43 9.0 0.0 0.65 8.5 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Trp_oprn_chp PF09534.5 GAK61859.1 - 1.5 8.4 8.6 0.46 10.0 2.6 2.1 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PPR_2 PF13041.1 GAK61860.1 - 1.2e-08 34.8 0.0 0.59 10.1 0.0 6.4 6 1 2 8 8 8 3 PPR repeat family PPR_3 PF13812.1 GAK61860.1 - 2.2e-08 33.7 7.4 1.1 9.7 0.0 7.4 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 GAK61860.1 - 0.00022 21.0 0.0 2.8 8.1 0.0 5.0 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 GAK61860.1 - 0.00083 18.7 0.0 3.6 7.1 0.0 3.6 4 0 0 4 4 4 2 PPR repeat B12-binding_2 PF02607.12 GAK61860.1 - 0.041 13.9 0.2 6 6.9 0.0 3.7 3 0 0 3 3 3 0 B12 binding domain TPR_14 PF13428.1 GAK61860.1 - 0.48 11.2 18.0 8 7.4 0.1 7.2 7 1 1 8 8 8 0 Tetratricopeptide repeat Ribosomal_L17 PF01196.14 GAK61861.1 - 1.6e-30 105.4 0.1 7.6e-30 103.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L17 PP-binding PF00550.20 GAK61862.1 - 4.1e-14 52.6 0.8 6e-14 52.0 0.5 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 GAK61862.1 - 1.8e-08 34.3 0.6 2.5e-08 33.8 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 GAK61862.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S Rav1p_C PF12234.3 GAK61863.1 - 1.5e-193 644.4 0.0 2.1e-193 644.0 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 GAK61863.1 - 0.048 13.5 17.6 3.9 7.5 0.0 7.0 7 0 0 7 7 7 0 WD domain, G-beta repeat UQ_con PF00179.21 GAK61864.1 - 1.1e-22 80.0 0.0 2.2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ras PF00071.17 GAK61865.1 - 1.6e-54 183.6 0.0 1.9e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK61865.1 - 1.3e-17 64.3 0.0 1.8e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK61865.1 - 5.7e-06 25.6 0.0 7.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAK61865.1 - 0.0022 17.4 0.0 0.026 13.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF336 PF03928.9 GAK61866.1 - 6.2e-16 58.3 0.0 8.3e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Ribosomal_S28e PF01200.13 GAK61867.1 - 3.7e-23 81.0 1.4 6.1e-23 80.3 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S28e CTP_synth_N PF06418.9 GAK61869.1 - 1.8e-116 388.0 0.0 2.6e-116 387.5 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 GAK61869.1 - 1.9e-49 167.7 0.0 7.3e-39 133.2 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.18 GAK61869.1 - 0.0022 17.4 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.8 GAK61869.1 - 0.087 12.2 0.0 0.75 9.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 zf-Nse PF11789.3 GAK61870.1 - 2.3e-13 49.4 0.0 4.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 GAK61870.1 - 5.5e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 GAK61870.1 - 0.0076 15.9 0.2 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 GAK61870.1 - 0.018 14.6 0.1 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRF PF01765.14 GAK61870.1 - 0.051 13.0 1.3 0.12 11.8 0.8 1.7 1 1 0 1 1 1 0 Ribosome recycling factor zf-C3HC4_2 PF13923.1 GAK61870.1 - 0.1 12.6 0.2 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 GAK61870.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Adaptin_N PF01602.15 GAK61871.1 - 2.4e-110 369.3 0.0 3.6e-110 368.7 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 GAK61871.1 - 8.4e-55 184.7 0.6 1.9e-54 183.6 0.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 GAK61871.1 - 3.1e-13 49.8 2.6 0.00076 19.7 0.1 6.5 3 2 4 7 7 7 3 HEAT repeats HEAT PF02985.17 GAK61871.1 - 9e-05 22.2 5.6 3.5 7.9 0.1 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_PBS PF03130.11 GAK61871.1 - 1.1 9.9 4.4 13 6.5 0.1 4.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat bZIP_2 PF07716.10 GAK61872.1 - 1.3e-08 34.5 14.9 1.3e-08 34.5 10.3 3.0 2 2 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 GAK61872.1 - 0.0023 17.8 12.4 0.0023 17.8 8.6 2.5 2 1 0 2 2 2 1 bZIP transcription factor HAP1_N PF04849.8 GAK61872.1 - 0.02 13.8 0.5 0.02 13.8 0.3 2.1 2 0 0 2 2 2 0 HAP1 N-terminal conserved region TSC22 PF01166.13 GAK61872.1 - 0.029 14.3 0.1 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Ist1 PF03398.9 GAK61872.1 - 0.087 12.2 1.5 0.14 11.5 1.0 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF2205 PF10224.4 GAK61872.1 - 0.68 9.5 4.7 0.29 10.7 0.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4011 PF13195.1 GAK61872.1 - 3.6 7.5 13.6 1.9 8.4 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) IncA PF04156.9 GAK61872.1 - 5 6.6 6.9 0.45 10.0 0.5 2.0 2 0 0 2 2 2 0 IncA protein WEMBL PF05701.6 GAK61873.1 - 2.7e-05 22.8 137.3 6.5e-05 21.5 34.4 11.8 1 1 9 10 10 10 4 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 GAK61873.1 - 0.00089 17.1 62.3 0.00089 17.1 43.2 10.9 1 1 3 7 7 7 3 Myosin tail Filament PF00038.16 GAK61873.1 - 0.00094 18.7 45.2 0.00094 18.7 31.3 16.6 2 1 13 16 16 16 10 Intermediate filament protein CENP-F_leu_zip PF10473.4 GAK61873.1 - 0.0033 17.2 11.0 0.0033 17.2 7.6 23.2 2 2 19 23 23 23 10 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 GAK61873.1 - 0.0043 16.6 17.0 0.0043 16.6 11.8 20.9 2 2 18 20 20 20 9 IncA protein Tup_N PF08581.5 GAK61873.1 - 0.026 14.6 0.4 0.026 14.6 0.3 22.1 15 8 9 27 27 27 0 Tup N-terminal PPR_2 PF13041.1 GAK61874.1 - 4.3e-08 33.0 0.1 0.29 11.1 0.0 4.8 5 0 0 5 5 5 2 PPR repeat family SPX PF03105.14 GAK61874.1 - 0.011 15.5 10.5 0.013 15.2 7.3 1.4 1 1 0 1 1 1 0 SPX domain ATP13 PF12921.2 GAK61874.1 - 0.09 12.1 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase expression phage_tail_N PF08400.5 GAK61874.1 - 0.52 10.0 0.0 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 Prophage tail fibre N-terminal Ank_4 PF13637.1 GAK61875.1 - 7.6e-12 45.4 0.0 1.6e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAK61875.1 - 7.7e-08 32.5 0.2 1.7e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_2 PF14608.1 GAK61875.1 - 2.3e-07 30.5 7.9 2.3e-07 30.5 5.5 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type Ank_5 PF13857.1 GAK61875.1 - 2.6e-07 30.6 0.3 0.00044 20.4 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAK61875.1 - 8.4e-07 28.4 0.2 2e-05 24.1 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH PF00642.19 GAK61875.1 - 1.8e-05 24.3 9.2 0.0063 16.1 0.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_3 PF13606.1 GAK61875.1 - 0.00028 20.8 0.0 0.011 15.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat MACPF PF01823.14 GAK61876.1 - 0.067 12.8 3.1 0.13 11.9 2.2 1.3 1 0 0 1 1 1 0 MAC/Perforin domain Pkinase PF00069.20 GAK61878.1 - 7.9e-49 166.1 0.0 1.2e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK61878.1 - 2.7e-23 82.3 0.0 3.5e-22 78.7 0.0 2.5 3 1 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK61878.1 - 0.0036 16.3 0.0 0.0072 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK61878.1 - 0.06 12.4 0.2 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Telomerase_RBD PF12009.3 GAK61879.1 - 1.6e-36 125.1 0.2 8.9e-36 122.7 0.0 2.3 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 GAK61879.1 - 2.5e-14 53.1 0.0 1.2e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) GHMP_kinases_N PF00288.21 GAK61880.1 - 6.8e-13 48.4 1.7 1.8e-12 47.1 1.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAK61880.1 - 2.1e-05 24.6 0.0 6.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal HLH PF00010.21 GAK61881.1 - 0.00087 18.9 0.0 0.0028 17.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain SET PF00856.23 GAK61882.1 - 1.8e-07 31.5 0.1 4.4e-05 23.8 0.0 2.6 3 0 0 3 3 3 2 SET domain dCMP_cyt_deam_1 PF00383.17 GAK61882.1 - 0.00013 21.5 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2404 PF10296.4 GAK61883.1 - 1.2e-29 102.3 0.0 2e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) GDI PF00996.13 GAK61884.1 - 4e-200 664.7 0.0 4.5e-200 664.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 GAK61884.1 - 0.057 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pex14_N PF04695.8 GAK61885.1 - 6.3e-17 61.9 0.5 3e-16 59.7 0.4 2.2 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Swi5 PF07061.6 GAK61886.1 - 2.1e-14 53.0 0.1 2.9e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Swi5 SNF2_N PF00176.18 GAK61888.1 - 2.5e-70 236.6 0.8 5.2e-70 235.6 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 GAK61888.1 - 1.5e-52 177.4 19.0 1.5e-52 177.4 13.2 2.6 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 GAK61888.1 - 7.9e-13 48.0 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK61888.1 - 1e-05 25.4 0.0 3e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PSGP PF07276.6 GAK61889.1 - 0.18 12.0 0.8 0.57 10.4 0.5 1.9 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) Shadoo PF14999.1 GAK61890.1 - 0.09 12.6 10.4 0.14 12.0 7.2 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Chorion_S16 PF05836.7 GAK61890.1 - 0.55 10.1 5.4 0.84 9.5 3.8 1.2 1 0 0 1 1 1 0 Chorion protein S16 Ribosomal_60s PF00428.14 GAK61890.1 - 0.71 10.3 12.0 1 9.7 8.3 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zn_clus PF00172.13 GAK61891.1 - 0.00029 20.6 15.1 0.00044 20.0 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SF3b10 PF07189.6 GAK61893.1 - 1.1e-29 102.0 0.0 1.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Ribosomal_L29 PF00831.18 GAK61895.1 - 3.8e-18 64.9 2.5 3.8e-18 64.9 1.7 1.6 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 GAK61895.1 - 0.018 15.3 1.8 0.027 14.7 1.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 HECT PF00632.20 GAK61895.1 - 0.019 14.1 0.0 1.1 8.3 0.0 2.3 2 1 0 2 2 2 0 HECT-domain (ubiquitin-transferase) SecE PF00584.15 GAK61896.1 - 7.7e-09 34.9 0.5 0.00097 18.6 0.3 2.2 2 0 0 2 2 2 2 SecE/Sec61-gamma subunits of protein translocation complex Img2 PF05046.9 GAK61897.1 - 5.2e-28 97.0 0.0 8.3e-28 96.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 GAK61897.1 - 0.13 12.0 0.0 0.8 9.5 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 MMR_HSR1 PF01926.18 GAK61898.1 - 5.5e-16 58.5 0.1 9e-15 54.6 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK61898.1 - 4.3e-05 22.8 0.0 0.00025 20.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 GAK61898.1 - 6.1e-05 22.2 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAK61898.1 - 0.0077 16.0 1.1 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 GAK61898.1 - 0.0098 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 GAK61898.1 - 0.03 14.8 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 GAK61898.1 - 0.073 12.5 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1253 PF06862.7 GAK61899.1 - 5.6e-158 525.9 0.1 6.9e-158 525.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) MSA-2c PF12238.3 GAK61899.1 - 0.088 12.4 6.3 0.21 11.2 4.3 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c MSP1_C PF07462.6 GAK61899.1 - 0.94 7.7 7.0 1.6 7.0 4.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NTR2 PF15458.1 GAK61900.1 - 3.6e-31 108.3 0.4 6.8e-31 107.4 0.3 1.5 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF3591 PF12157.3 GAK61901.1 - 1.2e-191 637.0 1.9 1.8e-191 636.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 GAK61901.1 - 0.00021 20.9 3.0 0.00048 19.7 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle ApbA_C PF08546.6 GAK61902.1 - 4.1e-37 126.9 0.0 7.1e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAK61902.1 - 1e-22 80.2 0.0 1.7e-18 66.5 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA SMC_N PF02463.14 GAK61903.1 - 2.6e-26 92.2 0.0 4.6e-26 91.4 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAK61903.1 - 1.5e-11 45.0 32.1 1.5e-11 45.0 22.2 5.5 3 2 0 3 3 1 1 AAA domain AAA_21 PF13304.1 GAK61903.1 - 1.6e-08 34.9 0.6 0.0002 21.4 0.1 3.3 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 GAK61903.1 - 1.3e-05 24.6 0.1 2.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 GAK61903.1 - 1.3e-05 24.4 0.1 1.3e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_13 PF13166.1 GAK61903.1 - 0.00025 19.6 63.0 0.012 14.0 13.0 4.2 3 1 1 4 4 4 2 AAA domain IFT57 PF10498.4 GAK61903.1 - 0.00035 19.4 7.8 0.00035 19.4 5.4 4.9 3 2 1 4 4 3 1 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.7 GAK61903.1 - 0.0032 17.2 8.3 0.0032 17.2 5.7 7.5 3 2 3 7 7 5 2 TPR/MLP1/MLP2-like protein ABC_tran PF00005.22 GAK61903.1 - 0.0064 16.7 0.1 0.0064 16.7 0.1 5.7 4 1 0 4 4 3 1 ABC transporter FtsK_SpoIIIE PF01580.13 GAK61903.1 - 0.049 13.0 0.0 0.049 13.0 0.0 4.3 5 0 0 5 5 5 0 FtsK/SpoIIIE family DUF106 PF01956.11 GAK61903.1 - 0.098 12.1 7.5 1.2 8.6 0.0 3.7 2 2 2 4 4 4 0 Integral membrane protein DUF106 AAA_18 PF13238.1 GAK61903.1 - 0.33 11.2 0.1 0.33 11.2 0.0 4.6 4 2 0 4 4 4 0 AAA domain AAA_25 PF13481.1 GAK61903.1 - 3.6 6.9 9.2 0.79 9.0 0.0 3.7 4 0 0 4 4 4 0 AAA domain Kelch_5 PF13854.1 GAK61904.1 - 1e-36 124.3 10.4 1.1e-09 37.9 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 GAK61904.1 - 2.9e-36 122.9 13.2 5.2e-09 35.7 0.2 7.3 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_3 PF13415.1 GAK61904.1 - 1.5e-35 120.5 14.5 4e-10 39.5 0.0 8.2 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 GAK61904.1 - 1.2e-29 101.6 8.7 3.7e-11 42.3 1.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 GAK61904.1 - 1.2e-28 98.0 9.9 7.6e-11 41.7 0.5 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAK61904.1 - 5.5e-22 76.6 13.1 2.2e-06 27.2 0.2 7.1 6 1 0 6 6 6 5 Kelch motif RAG2 PF03089.9 GAK61904.1 - 3.8 6.1 3.9 39 2.8 0.1 3.9 5 1 0 6 6 6 0 Recombination activating protein 2 zf-BED PF02892.10 GAK61906.1 - 0.12 12.1 0.2 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger TLD PF07534.11 GAK61908.1 - 2.6e-28 98.7 0.0 8.8e-26 90.5 0.0 2.3 2 0 0 2 2 2 2 TLD RhoGEF PF00621.15 GAK61909.1 - 1.2e-41 142.5 0.0 2e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 GAK61909.1 - 2e-12 46.4 3.2 1.4e-05 24.5 0.2 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK61909.1 - 3.7e-11 42.5 8.2 6.9e-07 28.9 0.2 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 GAK61909.1 - 6e-08 31.6 5.0 0.12 12.4 0.2 4.4 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_7 PF13504.1 GAK61909.1 - 0.0002 21.0 8.1 1.5 9.3 1.3 5.2 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 GAK61909.1 - 7.6 6.9 5.6 41 4.6 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat CPSF_A PF03178.10 GAK61911.1 - 9.3e-91 304.2 0.0 5.6e-89 298.3 0.0 2.8 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 GAK61911.1 - 1.8e-72 244.1 0.0 3.8e-72 243.0 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4407 PF14362.1 GAK61912.1 - 0.0013 17.7 0.9 0.0019 17.2 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF1240 PF06836.7 GAK61912.1 - 0.031 14.5 1.4 0.17 12.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) NfeD PF01957.13 GAK61912.1 - 0.32 11.1 2.6 0.15 12.1 0.3 1.6 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding Tetraspannin PF00335.15 GAK61912.1 - 0.33 10.2 13.7 0.034 13.4 5.3 1.9 1 1 0 2 2 2 0 Tetraspanin family zf-DHHC PF01529.15 GAK61912.1 - 1.8 7.8 8.9 0.15 11.4 2.4 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase MFS_1 PF07690.11 GAK61913.1 - 1.2e-26 93.3 22.0 5.1e-26 91.2 15.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ORMDL PF04061.9 GAK61913.1 - 0.048 13.2 3.6 0.084 12.4 1.0 2.3 2 0 0 2 2 2 0 ORMDL family Utp11 PF03998.8 GAK61914.1 - 1.8e-67 227.6 6.5 3.1e-67 226.9 4.5 1.4 1 0 0 1 1 1 1 Utp11 protein CtaG_Cox11 PF04442.9 GAK61914.1 - 2.8e-53 179.7 0.0 4.5e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 ORC4_C PF14629.1 GAK61916.1 - 3.6e-42 144.0 0.0 5.2e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 GAK61916.1 - 1.5e-29 103.3 2.1 2.2e-29 102.7 0.4 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 GAK61916.1 - 6.7e-06 26.3 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAK61916.1 - 9.6e-06 25.7 0.0 0.00011 22.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAK61916.1 - 0.00021 20.3 0.0 0.00034 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 GAK61916.1 - 0.00022 20.6 0.1 0.0007 19.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 GAK61916.1 - 0.0029 17.2 0.7 0.0071 15.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.2 GAK61916.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 ABC_tran PF00005.22 GAK61916.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 GAK61916.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Pox_A32 PF04665.7 GAK61916.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SNF2_N PF00176.18 GAK61917.1 - 9.4e-54 182.2 0.0 1.4e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK61917.1 - 9.1e-16 57.4 0.0 2.8e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK61917.1 - 3.9e-06 26.8 0.1 2.2e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 GAK61917.1 - 1.2e-05 24.3 0.0 2.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 GAK61917.1 - 0.0014 18.2 0.6 0.0071 15.9 0.1 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.1 GAK61917.1 - 0.0018 17.6 8.5 0.23 10.7 0.3 3.8 2 1 1 3 3 3 2 PHD/FYVE-zinc-finger like domain PHD PF00628.24 GAK61917.1 - 0.11 12.2 12.5 0.049 13.3 1.6 3.1 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.17 GAK61917.1 - 0.69 9.6 10.6 1.7 8.4 0.0 3.7 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rep_fac_C PF08542.6 GAK61918.1 - 3.6e-20 71.7 0.1 1.2e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAK61918.1 - 9.1e-13 48.1 0.0 8.2e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAK61918.1 - 1.6e-12 47.7 0.1 4.4e-12 46.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAK61918.1 - 1.3e-06 28.3 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 GAK61918.1 - 1.3e-06 27.3 0.0 0.0026 16.4 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 GAK61918.1 - 2.9e-06 27.3 0.2 0.00021 21.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.6 GAK61918.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAK61918.1 - 7.8e-05 22.8 0.1 0.0063 16.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAK61918.1 - 0.00023 20.2 0.0 0.00075 18.6 0.0 1.8 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 GAK61918.1 - 0.0005 19.6 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 GAK61918.1 - 0.001 18.6 0.1 0.24 10.7 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 GAK61918.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 GAK61918.1 - 0.0032 17.1 0.0 0.0091 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAK61918.1 - 0.0075 15.4 0.0 0.18 10.9 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 GAK61918.1 - 0.021 14.3 0.0 0.029 13.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 GAK61918.1 - 0.029 13.8 0.1 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NTPase_1 PF03266.10 GAK61918.1 - 0.031 13.9 0.2 0.43 10.2 0.0 2.2 1 1 1 2 2 2 0 NTPase MipZ PF09140.6 GAK61918.1 - 0.033 13.2 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ FtsK_SpoIIIE PF01580.13 GAK61918.1 - 0.038 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 GAK61918.1 - 0.074 11.8 0.0 0.32 9.7 0.0 1.9 1 1 1 2 2 2 0 ArgK protein DUF1302 PF06980.6 GAK61918.1 - 0.074 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) AAA_31 PF13614.1 GAK61918.1 - 0.075 12.9 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 GAK61918.1 - 0.094 12.1 0.2 0.33 10.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain PAP2 PF01569.16 GAK61920.1 - 4.4e-14 52.2 6.3 7.1e-14 51.5 2.7 2.1 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 GAK61920.1 - 0.0001 22.0 1.0 0.00088 19.0 0.1 2.4 2 0 0 2 2 2 1 Divergent PAP2 family DUF2614 PF11023.3 GAK61920.1 - 0.11 12.2 0.5 0.24 11.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) Ferritin_2 PF13668.1 GAK61921.1 - 1.4e-42 144.8 2.3 2.6e-42 144.0 1.6 1.5 1 0 0 1 1 1 1 Ferritin-like domain PAXNEB PF05625.6 GAK61922.1 - 9.8e-38 129.9 0.0 1.6e-24 86.4 0.0 3.4 3 0 0 3 3 3 3 PAXNEB protein DUF3719 PF12516.3 GAK61922.1 - 0.041 13.4 0.3 1.8 8.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3719) Aldo_ket_red PF00248.16 GAK61923.1 - 1.7e-55 187.8 0.0 2e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 GAK61924.1 - 4.1e-69 232.6 0.0 6.6e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK61924.1 - 1.3e-48 165.3 0.0 2e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK61924.1 - 0.00042 19.3 0.0 0.00083 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sugar_tr PF00083.19 GAK61925.1 - 6.3e-104 348.0 11.2 7.4e-104 347.8 7.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK61925.1 - 6.3e-23 81.0 21.3 6.3e-23 81.0 14.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAK61925.1 - 0.022 14.5 0.7 0.065 13.0 0.1 2.2 2 0 0 2 2 2 0 MFS_1 like family SAM_MT PF04445.8 GAK61925.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Complex1_51K PF01512.12 GAK61927.1 - 4.2e-49 166.1 0.0 6.5e-49 165.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 GAK61927.1 - 1e-19 69.3 0.5 2.2e-19 68.3 0.4 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 GAK61927.1 - 1.5e-07 31.2 0.0 3.3e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 SLBB domain TraE PF05309.6 GAK61928.1 - 0.13 11.3 0.1 0.24 10.5 0.1 1.5 1 0 0 1 1 1 0 TraE protein K1 PF02960.9 GAK61928.1 - 1.5 8.8 6.6 1.2 9.2 3.4 1.5 2 0 0 2 2 2 0 K1 glycoprotein DUF3493 PF11998.3 GAK61928.1 - 6.8 6.6 6.1 14 5.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) zf-Tim10_DDP PF02953.10 GAK61929.1 - 1.2e-21 75.7 0.5 1.5e-21 75.4 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RRM_6 PF14259.1 GAK61930.1 - 2.2e-11 43.5 0.0 7.9e-10 38.5 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK61930.1 - 5.8e-11 41.8 0.0 1.1e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK61930.1 - 0.00021 21.0 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 GAK61930.1 - 0.14 10.5 37.1 0.37 9.1 4.0 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Lin-8 PF03353.10 GAK61930.1 - 2.2 7.4 12.8 0.28 10.4 4.1 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Metallophos_C PF14008.1 GAK61931.1 - 0.065 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C NPL4 PF05021.10 GAK61932.1 - 2.7e-101 338.7 0.0 3.9e-101 338.2 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 GAK61932.1 - 1.5e-67 225.8 1.0 2.5e-67 225.0 0.7 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 GAK61932.1 - 0.00026 21.2 0.0 0.00078 19.6 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.13 GAK61932.1 - 0.00027 19.9 1.9 0.00027 19.9 1.3 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF2360 PF10152.4 GAK61932.1 - 0.18 12.0 2.2 0.78 10.0 0.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Adeno_E1A PF02703.9 GAK61932.1 - 6.4 6.1 7.6 0.34 10.3 0.8 2.1 3 0 0 3 3 3 0 Early E1A protein ABC_membrane PF00664.18 GAK61933.1 - 6.7e-64 215.9 28.2 3.9e-34 118.3 4.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAK61933.1 - 3.5e-55 186.0 0.1 3.3e-30 105.1 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 GAK61933.1 - 3.4e-12 46.9 0.1 0.055 13.4 0.0 4.4 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAK61933.1 - 3.6e-10 39.4 0.5 0.0006 19.1 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAK61933.1 - 5.7e-07 28.9 0.7 0.044 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 GAK61933.1 - 3e-06 27.7 0.4 0.12 12.8 0.2 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 GAK61933.1 - 3.2e-06 27.0 0.3 0.016 15.1 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 GAK61933.1 - 1.8e-05 24.8 2.6 0.066 13.2 0.0 3.3 4 0 0 4 4 2 2 AAA ATPase domain AAA_23 PF13476.1 GAK61933.1 - 2.2e-05 24.8 3.2 0.21 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 GAK61933.1 - 3.8e-05 23.1 0.7 0.048 13.0 0.1 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAK61933.1 - 9.6e-05 21.6 1.4 0.16 11.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAK61933.1 - 0.00016 22.4 0.0 1.1 10.0 0.0 3.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 GAK61933.1 - 0.00052 19.1 0.3 0.31 10.1 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 GAK61933.1 - 0.00075 19.3 3.2 0.37 10.5 0.1 2.9 2 0 0 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 GAK61933.1 - 0.0011 18.4 0.2 0.46 9.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 GAK61933.1 - 0.0032 16.4 1.0 1.4 7.7 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein ArgK PF03308.11 GAK61933.1 - 0.0053 15.5 0.6 0.24 10.1 0.1 2.3 2 0 0 2 2 2 1 ArgK protein MobB PF03205.9 GAK61933.1 - 0.0061 16.2 0.7 3 7.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 GAK61933.1 - 0.0072 16.4 0.4 4.3 7.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 GAK61933.1 - 0.0098 15.6 0.1 0.74 9.4 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 GAK61933.1 - 0.011 15.6 1.8 1.7 8.4 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 GAK61933.1 - 0.011 15.1 0.2 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 GAK61933.1 - 0.018 14.5 0.9 1.5 8.2 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 GAK61933.1 - 0.023 14.3 0.2 2 8.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 GAK61933.1 - 0.042 13.2 1.3 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 GAK61933.1 - 0.089 12.6 2.1 0.57 9.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 KAP_NTPase PF07693.9 GAK61933.1 - 0.15 11.0 0.0 4.4 6.2 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.1 GAK61933.1 - 0.23 11.7 1.8 14 5.9 0.1 3.1 2 0 0 2 2 2 0 AAA domain PA28_beta PF02252.13 GAK61934.1 - 2.2e-49 166.8 0.1 3.3e-49 166.1 0.1 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 GAK61934.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.7 1 1 0 1 1 1 0 Proteasome activator pa28 alpha subunit Sec5 PF15469.1 GAK61935.1 - 1e-53 181.8 0.0 2e-53 180.8 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 GAK61935.1 - 0.056 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Vps51/Vps67 Tim17 PF02466.14 GAK61936.1 - 8.1e-34 116.4 3.9 9.5e-34 116.2 2.7 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pyr_redox_3 PF13738.1 GAK61937.1 - 2.9e-25 89.5 0.0 1.7e-23 83.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK61937.1 - 5.2e-11 42.4 0.0 3.2e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAK61937.1 - 6.5e-11 41.7 0.0 1.6e-07 30.5 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAK61937.1 - 1.3e-10 40.6 0.0 6e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FMO-like PF00743.14 GAK61937.1 - 3.1e-10 38.8 0.8 3.4e-09 35.4 0.6 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 GAK61937.1 - 1.2e-06 28.4 0.0 0.0042 16.8 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAK61937.1 - 1.8e-05 23.8 0.0 0.055 12.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAK61937.1 - 2.3e-05 24.3 0.0 0.052 13.4 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK61937.1 - 0.00096 18.3 0.0 0.015 14.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 GAK61937.1 - 0.012 14.3 0.7 0.082 11.5 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 GAK61937.1 - 0.012 16.0 0.0 0.14 12.5 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAK61937.1 - 0.021 13.7 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 GAK61937.1 - 0.041 13.9 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 GAK61937.1 - 0.079 12.0 0.0 5.2 6.0 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Mqo PF06039.10 GAK61937.1 - 0.13 10.3 0.0 0.63 8.1 0.0 2.0 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Hepar_II_III PF07940.8 GAK61938.1 - 1.2e-09 38.1 2.0 2e-09 37.3 0.5 2.2 2 0 0 2 2 2 1 Heparinase II/III-like protein Arc_PepC_II PF06847.6 GAK61938.1 - 0.018 15.4 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II GATA PF00320.22 GAK61939.1 - 3.7e-14 51.7 5.4 6.7e-14 50.9 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger Ycf1 PF05758.7 GAK61939.1 - 0.38 8.4 8.2 0.6 7.7 5.7 1.3 1 0 0 1 1 1 0 Ycf1 PPR_2 PF13041.1 GAK61940.1 - 3.6e-12 46.0 0.0 0.00017 21.5 0.0 7.7 8 1 1 9 9 9 2 PPR repeat family PPR_3 PF13812.1 GAK61940.1 - 7.7e-09 35.1 10.5 0.0031 17.6 0.0 7.5 8 1 1 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 GAK61940.1 - 3.5e-08 32.8 1.4 0.023 14.6 0.0 6.1 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 GAK61940.1 - 0.0002 20.7 0.1 2.1 7.9 0.0 4.6 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.1 GAK61940.1 - 0.007 16.9 9.0 29 5.6 0.0 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat WD40 PF00400.27 GAK61941.1 - 1.6e-44 148.2 15.0 2.3e-08 33.6 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat 4HBT_2 PF13279.1 GAK61941.1 - 4.3e-12 46.5 0.1 8e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 GAK61941.1 - 0.0023 18.0 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 GAK61941.1 - 0.0078 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase zf-C2H2 PF00096.21 GAK61944.1 - 0.11 12.9 0.5 0.27 11.6 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type ADH_zinc_N PF00107.21 GAK61945.1 - 8.3e-15 54.4 0.2 3.2e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK61945.1 - 3.5e-11 42.8 0.0 7.3e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Es2 PF09751.4 GAK61946.1 - 2.3e-73 247.9 0.1 2.9e-73 247.6 0.1 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 ODC_AZ PF02100.12 GAK61947.1 - 2.1e-25 88.2 0.0 3.5e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme UCH PF00443.24 GAK61948.1 - 5.4e-30 104.4 0.0 7.6e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAK61948.1 - 8.6e-11 41.7 0.1 2.1e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 GAK61948.1 - 1.3e-06 28.0 0.0 7e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.11 GAK61949.1 - 1.5e-19 69.9 38.8 2.6e-17 62.5 24.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Tetraspannin PF00335.15 GAK61949.1 - 0.22 10.7 6.7 1.6 7.9 0.0 3.1 3 0 0 3 3 3 0 Tetraspanin family DUF2207 PF09972.4 GAK61949.1 - 0.7 8.4 0.1 19 3.7 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Glyco_hydro_20 PF00728.17 GAK61950.1 - 4.4e-77 259.6 0.0 7.2e-77 258.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAK61950.1 - 4.3e-15 56.5 0.0 1.2e-14 55.0 0.0 1.8 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAK61950.1 - 1.9e-06 28.4 0.0 0.00011 22.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Acyl-CoA_dh_1 PF00441.19 GAK61951.1 - 6.9e-34 117.1 5.2 1.5e-33 116.0 3.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAK61951.1 - 4.7e-19 67.6 0.1 1.2e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAK61951.1 - 6.7e-17 62.0 1.5 2.1e-16 60.5 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAK61951.1 - 1.8e-12 47.6 9.6 1.9e-12 47.5 3.8 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3818 PF12825.2 GAK61952.1 - 5.3e-44 150.2 0.0 1e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 GAK61952.1 - 5.2e-25 87.6 0.0 1.1e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 PX-associated Pescadillo_N PF06732.6 GAK61953.1 - 1.8e-116 388.2 0.1 1.8e-116 388.2 0.1 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 GAK61953.1 - 0.005 16.9 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain GPI-anchored PF10342.4 GAK61954.1 - 6.3e-10 39.4 1.0 6.3e-10 39.4 0.7 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_62 PF03664.8 GAK61955.1 - 7.8e-141 467.9 5.8 9e-141 467.7 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Pkinase PF00069.20 GAK61957.1 - 2.2e-53 181.0 0.0 6.2e-53 179.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK61957.1 - 6.8e-25 87.6 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK61957.1 - 0.028 14.1 0.3 0.061 13.0 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family EXOSC1 PF10447.4 GAK61958.1 - 1.9e-29 101.4 0.0 2.7e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 GAK61958.1 - 0.0027 16.9 1.8 0.022 14.0 1.2 2.5 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region LTV PF04180.9 GAK61959.1 - 3.5e-49 168.4 9.1 3.5e-49 168.4 6.3 3.1 2 2 0 2 2 2 1 Low temperature viability protein Peptidase_M28 PF04389.12 GAK61960.1 - 1.4e-26 93.3 0.2 2.5e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAK61960.1 - 1.5e-06 27.8 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 GAK61961.1 - 3.6e-25 86.8 13.4 1.3e-07 31.2 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Minor_capsid_2 PF11114.3 GAK61961.1 - 0.078 12.8 0.3 0.36 10.7 0.1 2.1 2 0 0 2 2 2 0 Minor capsid protein BBS2_Mid PF14783.1 GAK61961.1 - 0.09 12.5 0.0 20 5.0 0.0 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Ribosomal_L22e PF01776.12 GAK61962.1 - 1.6e-47 160.0 0.4 1.9e-47 159.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family SSB PF00436.20 GAK61962.1 - 0.1 12.4 0.2 0.19 11.6 0.1 1.5 2 0 0 2 2 2 0 Single-strand binding protein family DKCLD PF08068.7 GAK61963.1 - 1.8e-29 101.4 0.3 1.7e-28 98.3 0.0 2.7 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 GAK61963.1 - 1.8e-24 86.6 0.3 1.5e-21 77.0 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 GAK61963.1 - 3.5e-20 71.5 1.3 6.9e-20 70.5 0.9 1.5 1 0 0 1 1 1 1 PUA domain Exo_endo_phos PF03372.18 GAK61964.1 - 3.3e-11 43.5 1.7 4.3e-11 43.2 1.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_1 PF00175.16 GAK61965.1 - 2e-07 31.5 0.0 0.0037 17.8 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAK61965.1 - 0.0028 17.7 0.0 0.007 16.4 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAK61965.1 - 0.013 15.4 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain SR-25 PF10500.4 GAK61965.1 - 1.9 7.9 3.6 3.4 7.0 2.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acyltransferase PF01553.16 GAK61966.1 - 3.2e-22 78.3 0.0 4.9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Transpep_BrtH PF14399.1 GAK61966.1 - 0.035 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase zf-Tim10_DDP PF02953.10 GAK61967.1 - 3e-22 77.6 0.9 3.8e-22 77.3 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.6 GAK61967.1 - 0.71 9.6 3.5 0.11 12.2 0.2 1.4 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein APC10 PF03256.11 GAK61968.1 - 8.3e-47 159.2 0.0 1.3e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) MFS_1 PF07690.11 GAK61969.1 - 4.9e-41 140.6 36.6 2.1e-39 135.2 25.7 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK61969.1 - 4e-13 48.7 8.4 4e-13 48.7 5.8 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter S1 PF00575.18 GAK61970.1 - 1.7e-52 175.4 33.2 1.5e-11 44.1 0.7 9.2 9 0 0 9 9 9 8 S1 RNA binding domain Suf PF05843.9 GAK61970.1 - 1.7e-08 34.5 17.7 8.8e-06 25.6 0.2 5.1 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 GAK61970.1 - 2e-06 28.0 4.7 7.8e-05 22.9 0.4 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAK61970.1 - 0.0004 20.7 3.2 5.5 7.9 0.5 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK61970.1 - 0.003 18.1 14.5 0.55 10.9 0.6 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Nop14 PF04147.7 GAK61970.1 - 0.0041 15.1 42.3 0.17 9.7 4.8 3.2 3 0 0 3 3 3 3 Nop14-like family TPR_12 PF13424.1 GAK61970.1 - 0.0098 15.8 3.2 2 8.3 0.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAK61970.1 - 0.2 12.1 3.5 4 8.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AdoMet_MTase PF07757.8 GAK61971.1 - 9.3e-35 119.1 0.0 1.5e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 GAK61971.1 - 7.5e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK61971.1 - 0.00052 20.5 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK61971.1 - 0.0042 16.8 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK61971.1 - 0.0062 16.1 0.1 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK61971.1 - 0.07 13.1 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAK61971.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ABC1 PF03109.11 GAK61972.1 - 6.7e-22 77.6 0.0 7.2e-14 51.7 0.0 2.5 2 0 0 2 2 2 2 ABC1 family WD40 PF00400.27 GAK61973.1 - 3.2e-11 42.6 5.1 0.0029 17.4 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Uricase PF01014.13 GAK61974.1 - 1.1e-63 213.4 0.0 2.6e-36 124.7 0.1 2.0 2 0 0 2 2 2 2 Uricase Ecl1 PF12855.2 GAK61976.1 - 0.00035 19.8 0.1 0.0007 18.8 0.1 1.5 1 0 0 1 1 1 1 Life-span regulatory factor DUF2116 PF09889.4 GAK61976.1 - 0.0021 17.8 0.9 0.0044 16.7 0.6 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-ribbon_3 PF13248.1 GAK61976.1 - 0.14 11.4 1.3 0.29 10.3 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RINGv PF12906.2 GAK61977.1 - 1.9e-10 40.5 3.6 3.5e-10 39.7 2.5 1.4 1 0 0 1 1 1 1 RING-variant domain Cytochrom_C552 PF02335.10 GAK61977.1 - 0.055 12.1 0.0 0.092 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c552 DEAD PF00270.24 GAK61978.1 - 1.3e-38 132.0 0.1 2.6e-37 127.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK61978.1 - 8.6e-18 63.9 0.2 2.9e-17 62.2 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK61978.1 - 0.079 12.7 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3113 PF11310.3 GAK61978.1 - 0.18 11.5 0.2 0.4 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Adaptin_N PF01602.15 GAK61979.1 - 1.1e-149 499.1 6.2 1.3e-149 498.8 4.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 GAK61979.1 - 7.9e-23 80.9 0.5 1.4e-22 80.1 0.4 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 GAK61979.1 - 1.6e-09 37.8 2.5 0.073 13.3 0.1 6.2 5 3 1 6 6 6 2 HEAT repeats HEAT PF02985.17 GAK61979.1 - 0.00056 19.7 0.4 23 5.3 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat TIP120 PF08623.5 GAK61979.1 - 0.0028 17.2 4.8 0.028 14.0 0.2 3.9 3 2 1 4 4 4 1 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 GAK61979.1 - 0.008 16.0 7.1 0.071 12.9 0.5 4.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 GAK61979.1 - 0.1 12.4 1.1 18 5.3 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Hist_deacetyl PF00850.14 GAK61980.1 - 5.3e-80 269.0 0.0 6.8e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Nuc_sug_transp PF04142.10 GAK61981.1 - 9.8e-09 34.6 0.1 1.6e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 GAK61981.1 - 2.1e-07 30.1 8.0 2.1e-07 30.1 5.5 1.4 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 GAK61981.1 - 3e-05 23.7 17.5 0.0054 16.3 6.1 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 GAK61981.1 - 0.00059 19.8 4.5 0.00059 19.8 3.2 3.6 3 1 1 4 4 4 1 EamA-like transporter family HECT PF00632.20 GAK61982.1 - 3.7e-92 308.8 0.1 5.5e-92 308.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 GAK61982.1 - 4.5e-32 109.5 21.0 4e-11 42.5 2.1 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 GAK61982.1 - 5.2e-16 58.2 0.2 1.3e-15 56.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain SlyX PF04102.7 GAK61983.1 - 0.053 13.8 0.1 0.053 13.8 0.1 2.9 3 1 1 4 4 4 0 SlyX FliJ PF02050.11 GAK61983.1 - 3.4 7.7 6.2 2.2 8.3 0.1 2.8 3 0 0 3 3 3 0 Flagellar FliJ protein Complex1_LYR PF05347.10 GAK61984.1 - 1.6e-07 30.9 0.0 5.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAK61984.1 - 5.5e-06 26.5 0.2 1.6e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_L31 PF01197.13 GAK61984.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 DNA_pol_viral_N PF00242.12 GAK61984.1 - 0.28 10.1 4.4 0.37 9.7 3.1 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RNase_T PF00929.19 GAK61986.1 - 8e-11 42.5 0.0 1.4e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 Exonuclease SAP PF02037.22 GAK61986.1 - 1.1e-09 37.5 2.9 2.6e-09 36.3 2.0 1.7 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 GAK61986.1 - 0.0064 16.0 0.2 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain DUF1389 PF07146.6 GAK61986.1 - 0.027 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) RRM_1 PF00076.17 GAK61987.1 - 6.4e-07 28.9 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK61987.1 - 1.1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK61987.1 - 0.00062 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 GAK61987.1 - 0.0011 18.7 0.3 0.0011 18.7 0.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger DUF2256 PF10013.4 GAK61987.1 - 0.14 11.9 0.4 0.14 11.9 0.3 3.2 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) AMPKBI PF04739.10 GAK61988.1 - 3.6e-29 100.5 0.0 1.5e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain MAT1 PF06391.8 GAK61991.1 - 6.9e-37 126.9 22.0 6.9e-37 126.9 15.2 1.7 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 GAK61991.1 - 0.00028 20.4 9.2 0.0014 18.2 6.6 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK61991.1 - 0.0003 20.4 7.0 0.00095 18.8 5.0 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAK61991.1 - 0.00051 19.6 8.0 0.002 17.7 5.7 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 GAK61991.1 - 0.0056 16.2 6.5 0.061 12.9 1.6 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 GAK61991.1 - 0.0075 16.2 10.0 0.14 12.1 7.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ISL3 PF14690.1 GAK61991.1 - 0.038 14.0 0.5 0.67 10.0 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 GAK61991.1 - 0.3 10.9 6.3 0.97 9.2 4.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 GAK61991.1 - 0.3 10.3 3.5 2.2 7.6 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 GAK61991.1 - 1.7 8.4 6.4 0.7 9.6 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_2 PF13639.1 GAK61991.1 - 2.2 8.1 12.9 1.9 8.3 6.9 2.3 2 1 1 3 3 3 0 Ring finger domain zinc_ribbon_2 PF13240.1 GAK61991.1 - 4.8 6.7 8.3 1.9 8.0 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 GAK61991.1 - 5.4 7.0 10.2 18 5.3 0.1 2.9 2 1 0 2 2 2 0 Zinc ribbon domain PIG-U PF06728.8 GAK61992.1 - 1.9e-114 382.4 14.1 2.3e-114 382.2 9.8 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Arf PF00025.16 GAK61993.1 - 3e-66 221.9 0.0 3.5e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAK61993.1 - 6.1e-14 51.5 1.9 1.1e-09 37.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 GAK61993.1 - 9e-11 41.3 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 GAK61993.1 - 8e-10 39.2 0.0 1.1e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAK61993.1 - 6.2e-09 35.3 0.0 7.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAK61993.1 - 3.2e-08 33.5 0.0 1.2e-07 31.7 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 GAK61993.1 - 4.7e-08 32.5 0.0 5.5e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 GAK61993.1 - 8.1e-05 22.1 0.0 0.0012 18.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAK61993.1 - 0.0064 15.7 0.1 0.02 14.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 GAK61993.1 - 0.015 16.1 0.0 0.021 15.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAK61993.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 XS PF03468.9 GAK61993.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 XS domain Glyco_hydro_9 PF00759.14 GAK61994.1 - 5.9e-95 318.7 13.1 8e-52 176.6 2.9 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 9 VSP PF03302.8 GAK61994.1 - 0.0016 17.1 0.7 0.0033 16.1 0.2 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF500 PF04366.7 GAK61995.1 - 6.7e-39 132.2 0.0 1.4e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 GAK61995.1 - 7.7e-16 57.2 0.1 1.7e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAK61995.1 - 2.4e-13 49.4 0.0 4.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAK61995.1 - 3.2e-10 39.3 0.0 6.9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain LRR_4 PF12799.2 GAK61996.1 - 6.5e-06 25.6 19.8 0.063 12.9 0.8 7.1 6 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK61996.1 - 6.7e-06 25.7 5.8 1.5 8.6 0.2 4.9 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 GAK61996.1 - 2.5e-05 23.8 9.6 6.2 7.2 0.1 7.9 9 0 0 9 9 9 1 Leucine Rich repeat SeleniumBinding PF11524.3 GAK61996.1 - 0.11 12.5 0.1 4.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Selenium binding protein Arrestin_N PF00339.24 GAK61998.1 - 0.12 12.1 0.0 0.87 9.3 0.0 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Ribosomal_S13_N PF08069.7 GAK61999.1 - 5.1e-31 106.3 0.4 9.3e-31 105.4 0.3 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 GAK61999.1 - 1.9e-22 78.8 0.1 3.3e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 GAK61999.1 - 0.004 16.8 0.1 0.0088 15.7 0.0 1.6 2 0 0 2 2 2 1 'Paired box' domain Ribosomal_S6e PF01092.14 GAK62000.1 - 2.7e-57 191.8 0.2 5.7e-57 190.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e CD24 PF14984.1 GAK62000.1 - 0.038 13.7 0.1 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 CD24 protein TPR_1 PF00515.23 GAK62001.1 - 1.6e-26 90.7 11.0 1.5e-05 24.3 0.0 8.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAK62001.1 - 6.6e-25 86.5 12.4 7.4e-11 41.5 0.4 5.7 4 1 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 GAK62001.1 - 1.4e-20 71.4 17.0 0.00081 19.1 0.1 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat APC8 PF04049.8 GAK62001.1 - 4.2e-19 68.6 0.0 2.1e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.1 GAK62001.1 - 3.1e-18 64.1 2.8 4.3e-05 23.0 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAK62001.1 - 9.3e-16 57.5 18.0 2.5e-06 27.3 0.1 7.4 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAK62001.1 - 4.9e-11 42.2 18.6 0.0021 18.5 0.1 9.8 6 2 5 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAK62001.1 - 6.3e-11 41.2 11.0 0.46 10.4 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 GAK62001.1 - 9.9e-11 41.6 10.3 0.0029 17.7 0.3 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 GAK62001.1 - 3.1e-10 40.4 24.6 1.7e-08 34.8 1.0 7.8 8 1 2 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAK62001.1 - 2.5e-09 36.6 6.2 0.012 15.7 0.2 7.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAK62001.1 - 5.2e-07 29.6 8.5 0.37 11.3 0.2 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAK62001.1 - 1.4e-06 28.5 6.3 0.0052 17.0 0.0 5.5 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAK62001.1 - 0.00011 21.9 19.0 0.11 12.3 0.1 6.8 5 1 1 7 7 7 3 Tetratricopeptide repeat Epimerase PF01370.16 GAK62002.1 - 3.2e-05 23.4 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAK62002.1 - 0.024 14.6 0.1 0.058 13.3 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding UQ_con PF00179.21 GAK62004.1 - 2.5e-43 146.8 0.0 3.6e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1691 PF07950.6 GAK62004.1 - 1.1e-07 31.7 3.3 0.00028 20.7 0.2 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1691) Senescence PF06911.7 GAK62005.1 - 5.6e-47 159.7 6.1 9.1e-47 159.0 4.2 1.3 1 0 0 1 1 1 1 Senescence-associated protein Herpes_capsid PF06112.6 GAK62005.1 - 0.25 11.3 11.4 0.17 11.9 3.1 3.0 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein FAD_binding_6 PF00970.19 GAK62006.1 - 1.2e-31 108.7 0.0 1.9e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAK62006.1 - 5.6e-29 100.8 0.0 8.5e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAK62006.1 - 5.2e-09 36.1 0.0 4.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAK62006.1 - 0.0046 16.8 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain RhoGAP PF00620.22 GAK62007.1 - 2.1e-37 128.0 0.0 5.9e-37 126.6 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 GAK62007.1 - 0.0053 16.9 0.3 0.023 14.8 0.2 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain TPR_MLP1_2 PF07926.7 GAK62008.1 - 0.02 14.6 3.1 0.043 13.5 2.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tmemb_cc2 PF10267.4 GAK62008.1 - 3.6 6.0 10.7 0.018 13.6 0.7 2.0 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein CENP-W PF15510.1 GAK62009.1 - 0.028 14.4 0.3 0.099 12.6 0.2 1.9 1 1 0 1 1 1 0 Centromere kinetochore component W MitMem_reg PF13012.1 GAK62010.1 - 1.8e-17 63.4 0.4 3.3e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 GAK62010.1 - 3.9e-13 49.1 0.0 4.5e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FAD_binding_3 PF01494.14 GAK62012.1 - 1.8e-56 191.7 0.1 3.8e-55 187.3 0.1 2.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAK62012.1 - 2.4e-18 66.3 0.0 4.5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 GAK62012.1 - 5.9e-06 26.2 0.0 1.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK62012.1 - 7.5e-05 21.7 0.0 0.00021 20.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK62012.1 - 8.2e-05 21.2 0.0 0.00013 20.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 GAK62012.1 - 0.00071 18.6 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAK62012.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAK62012.1 - 0.0017 17.2 0.1 0.0036 16.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAK62012.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK62012.1 - 0.0059 15.7 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 GAK62012.1 - 0.0092 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAK62012.1 - 0.03 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAK62012.1 - 0.041 13.3 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 GAK62012.1 - 0.12 11.7 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 GAK62012.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 GAK62012.1 - 0.13 12.2 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain 3HCDH_N PF02737.13 GAK62012.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 GAK62012.1 - 0.22 10.4 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Nup160 PF11715.3 GAK62013.1 - 6.2e-120 400.9 0.0 8.5e-120 400.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_9 PF13371.1 GAK62013.1 - 0.0047 16.7 0.2 0.22 11.4 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAK62013.1 - 0.095 12.8 0.5 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAK62013.1 - 3.4 8.0 9.8 1.5 9.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.16 GAK62014.1 - 8.5e-23 80.3 0.0 1.8e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.6 GAK62014.1 - 0.0086 14.0 6.4 0.012 13.4 4.5 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Abhydrolase_3 PF07859.8 GAK62015.1 - 9.4e-34 116.8 0.0 1.7e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK62015.1 - 1.7e-06 28.0 0.5 7.1e-06 26.0 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK62015.1 - 7.3e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAK62015.1 - 7.3e-05 22.3 0.0 0.0085 15.5 0.0 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 GAK62015.1 - 0.00033 19.9 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAK62015.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 GAK62015.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 GAK62015.1 - 0.073 11.5 0.0 0.3 9.5 0.0 1.8 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_M20 PF01546.23 GAK62016.1 - 3e-23 82.3 0.0 4.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAK62016.1 - 1.3e-13 50.6 0.0 3.4e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain EthD PF07110.6 GAK62017.1 - 3.5e-10 40.6 0.4 9.8e-09 36.0 0.1 2.2 2 0 0 2 2 2 1 EthD domain Mitofilin PF09731.4 GAK62019.1 - 1.6e-147 492.7 22.9 1.8e-147 492.5 15.9 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein 2Fe-2S_thioredx PF01257.14 GAK62020.1 - 2.1e-59 199.2 0.1 2.7e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 GAK62020.1 - 0.035 14.3 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) HTH_30 PF13556.1 GAK62020.1 - 0.079 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Fer4 PF00037.22 GAK62021.1 - 4.2e-14 51.4 16.9 1.9e-08 33.5 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 GAK62021.1 - 2.2e-12 47.1 10.8 3.6e-12 46.4 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 GAK62021.1 - 9e-10 38.2 5.4 7.4e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 GAK62021.1 - 9.1e-10 39.1 8.0 9.3e-05 23.0 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 GAK62021.1 - 1.8e-09 37.2 23.1 7.4e-08 32.0 9.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAK62021.1 - 3.2e-09 36.9 11.1 5.8e-09 36.0 7.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 GAK62021.1 - 2.6e-08 33.2 14.6 0.0001 21.9 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 GAK62021.1 - 3.6e-08 33.3 20.0 2.3e-05 24.3 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 GAK62021.1 - 9.5e-08 31.5 18.0 0.00081 19.1 3.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 GAK62021.1 - 2.8e-06 27.5 9.0 0.00074 19.8 7.4 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 GAK62021.1 - 3.9e-06 26.7 12.3 0.00087 19.4 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 GAK62021.1 - 4.2e-05 23.8 9.9 0.023 15.0 0.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 GAK62021.1 - 0.00018 22.0 7.8 0.074 13.6 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 GAK62021.1 - 0.00038 20.7 12.5 0.057 13.8 0.7 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 GAK62021.1 - 0.05 14.1 18.1 0.086 13.4 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.1 GAK62021.1 - 0.13 12.1 4.1 0.22 11.4 2.9 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.5 GAK62021.1 - 0.14 12.3 4.4 0.36 10.9 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain RNase_H2-Ydr279 PF09468.5 GAK62022.1 - 2.2e-16 59.9 0.0 5.3e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) VCBS PF13517.1 GAK62023.1 - 6.1e-23 80.9 16.6 8.9e-08 32.3 1.7 6.4 5 1 1 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAK62023.1 - 6.1e-18 63.9 14.2 6e-05 22.6 0.1 6.5 6 0 0 6 6 6 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 GAK62023.1 - 6.4e-05 22.4 1.8 7.6 5.9 0.0 5.2 5 1 0 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region DUF1214 PF06742.6 GAK62023.1 - 0.11 12.9 0.6 23 5.4 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1214) V_ATPase_I PF01496.14 GAK62024.1 - 8.6e-263 873.7 0.0 9.7e-263 873.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.7 GAK62024.1 - 0.76 10.1 2.9 9.1 6.7 0.6 2.9 3 0 0 3 3 3 0 SlyX Cep57_MT_bd PF06657.8 GAK62024.1 - 0.88 9.5 6.2 0.18 11.7 0.4 2.7 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 VPS11_C PF12451.3 GAK62025.1 - 0.085 12.7 0.9 13 5.7 0.0 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal ApoO PF09769.4 GAK62025.1 - 0.1 12.3 0.1 0.79 9.4 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O CBM_21 PF03370.8 GAK62026.1 - 5.6e-30 103.6 0.0 9.7e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Serglycin PF04360.7 GAK62026.1 - 0.035 13.8 4.0 0.086 12.5 2.8 1.6 1 0 0 1 1 1 0 Serglycin DUF2205 PF10224.4 GAK62028.1 - 9e-13 47.6 0.3 1.1e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Cob_adeno_trans PF01923.13 GAK62028.1 - 0.049 13.4 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase ORC3_N PF07034.6 GAK62030.1 - 2.7e-13 49.6 0.0 2.1e-05 23.6 0.0 2.8 3 0 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus CDP-OH_P_transf PF01066.16 GAK62031.1 - 2e-19 69.7 5.3 5.1e-19 68.4 3.7 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4187 PF13821.1 GAK62032.1 - 3.4e-17 61.7 6.5 3.4e-17 61.7 4.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 GAK62032.1 - 1.3e-06 28.0 0.8 3.1e-06 26.8 0.5 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 GAK62032.1 - 0.1 12.7 4.0 0.27 11.4 2.7 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding A2L_zn_ribbon PF08792.5 GAK62032.1 - 0.15 11.5 1.8 0.31 10.5 1.3 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-C2H2 PF00096.21 GAK62032.1 - 3.6 8.1 7.7 3.8 8.0 2.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type CDC45 PF02724.9 GAK62032.1 - 6.3 4.7 13.7 0.087 10.8 1.9 2.3 3 0 0 3 3 3 0 CDC45-like protein AAA PF00004.24 GAK62033.1 - 6.3e-42 142.8 0.0 2e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAK62033.1 - 8.1e-06 26.0 0.0 0.00058 20.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAK62033.1 - 1.1e-05 25.2 0.1 5.9e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAK62033.1 - 9.8e-05 22.4 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 GAK62033.1 - 0.0002 21.3 0.0 0.00065 19.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAK62033.1 - 0.00098 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAK62033.1 - 0.0023 18.7 0.5 0.005 17.6 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 GAK62033.1 - 0.0034 17.0 0.1 0.0081 15.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 GAK62033.1 - 0.0041 16.1 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 GAK62033.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAK62033.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 GAK62033.1 - 0.015 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAK62033.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 GAK62033.1 - 0.021 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 GAK62033.1 - 0.025 14.2 0.0 6.6 6.3 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 GAK62033.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAK62033.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 GAK62033.1 - 0.043 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 GAK62033.1 - 0.05 12.3 0.0 0.091 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 GAK62033.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAK62033.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAK62033.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 GAK62033.1 - 0.095 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 GAK62033.1 - 0.13 11.6 0.3 0.66 9.3 0.0 2.0 1 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 GAK62034.1 - 6.1e-110 365.8 0.0 1.1e-109 364.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAK62034.1 - 1.4e-21 77.0 0.2 3.1e-21 75.9 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAK62034.1 - 6.6e-14 51.8 4.3 8.7e-14 51.4 2.3 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DASH_Dad2 PF08654.5 GAK62035.1 - 2.2e-29 101.4 0.0 2.7e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF3348 PF11828.3 GAK62035.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) SCA7 PF08313.7 GAK62036.1 - 2.2e-30 104.0 0.3 4.7e-30 102.9 0.2 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain BRF1 PF07741.8 GAK62036.1 - 2.6 8.3 7.1 1.7 8.9 1.8 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Exo_endo_phos PF03372.18 GAK62037.1 - 1.4e-15 57.8 0.2 3.1e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAK62037.1 - 5.8e-11 42.0 0.1 2.7e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 GAK62037.1 - 2.6e-07 30.4 6.1 4.2e-06 26.5 3.7 2.9 1 1 1 2 2 2 1 GRF zinc finger Peptidase_M22 PF00814.20 GAK62038.1 - 1.2e-70 238.1 1.0 1.5e-70 237.7 0.7 1.1 1 0 0 1 1 1 1 Glycoprotease family CoatB PF10389.4 GAK62039.1 - 0.073 12.9 0.1 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B Fcf1 PF04900.7 GAK62040.1 - 1e-39 134.6 0.7 3.7e-39 132.8 0.3 1.8 2 0 0 2 2 2 1 Fcf1 MRP-L28 PF09812.4 GAK62040.1 - 0.12 12.1 0.4 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Porin_3 PF01459.17 GAK62041.1 - 1.1e-75 254.4 2.2 1.3e-75 254.2 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin TFIIS_M PF07500.9 GAK62042.1 - 2.7e-21 75.7 0.5 8.2e-21 74.2 0.4 1.9 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 GAK62042.1 - 6e-15 55.7 0.0 1.4e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 GAK62042.1 - 1.5e-12 46.9 8.7 2.5e-12 46.2 6.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAK62042.1 - 0.035 13.4 3.0 0.06 12.6 2.1 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 GAK62042.1 - 0.32 11.2 2.6 1.2 9.4 1.8 2.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx zf-RING_2 PF13639.1 GAK62043.1 - 1.5e-07 31.1 5.9 1.5e-07 31.1 4.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 GAK62043.1 - 1.8e-06 27.9 1.3 3.7e-06 26.9 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAK62043.1 - 0.002 17.9 1.6 0.0043 16.8 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 GAK62043.1 - 0.0039 17.1 3.1 0.0097 15.8 2.1 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 GAK62043.1 - 0.01 15.8 5.4 0.026 14.5 3.7 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 GAK62043.1 - 0.016 14.9 0.8 0.031 14.0 0.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 GAK62043.1 - 0.044 13.4 7.6 0.084 12.5 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 GAK62043.1 - 2.7 7.6 4.9 5.2 6.7 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 GAK62043.1 - 6.1 6.9 4.7 12 6.0 3.2 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 GAK62043.1 - 6.6 6.5 4.6 14 5.5 3.2 1.5 1 0 0 1 1 1 0 PHD-finger Lactamase_B_2 PF12706.2 GAK62044.1 - 0.00031 20.3 1.3 0.00048 19.7 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.9 GAK62044.1 - 0.015 15.3 0.1 0.097 12.7 0.0 2.2 1 1 0 1 1 1 0 DNA repair metallo-beta-lactamase Telomere_Sde2 PF13019.1 GAK62045.1 - 2.6e-37 128.0 0.9 2.6e-37 128.0 0.6 1.6 2 0 0 2 2 2 1 Telomere stability and silencing DUF1116 PF06545.6 GAK62045.1 - 0.043 12.9 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) DUF572 PF04502.8 GAK62045.1 - 0.089 11.9 11.2 0.11 11.7 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GTSE1_N PF15259.1 GAK62045.1 - 1.3 9.0 6.7 0.12 12.3 0.2 2.1 1 1 1 2 2 2 0 G-2 and S-phase expressed 1 Striatin PF08232.7 GAK62045.1 - 2 8.7 7.3 3.2 8.0 5.0 1.3 1 0 0 1 1 1 0 Striatin family GHL12 PF14882.1 GAK62046.1 - 2.4 8.3 4.8 2.7 8.1 0.1 2.6 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 12 Phosducin PF02114.11 GAK62047.1 - 6.9e-12 44.6 0.0 1.1e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Phosducin GST_N_3 PF13417.1 GAK62047.1 - 2.8e-07 30.6 0.0 6.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK62047.1 - 0.00023 21.0 0.0 0.00047 20.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAK62047.1 - 0.031 14.2 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FoP_duplication PF13865.1 GAK62047.1 - 0.1 13.0 5.9 0.052 14.0 1.4 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 PUF PF00806.14 GAK62049.1 - 2.2e-56 184.2 0.0 1.5e-06 27.3 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 GAK62049.1 - 0.022 15.0 1.7 3 8.1 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function DUF260 FliG_C PF01706.11 GAK62049.1 - 0.089 12.7 0.2 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 FliG C-terminal domain Alg6_Alg8 PF03155.10 GAK62050.1 - 2.2e-119 399.4 23.6 7.6e-118 394.3 13.0 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family SGS PF05002.10 GAK62051.1 - 1.2e-26 92.2 0.7 2.3e-26 91.3 0.5 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.11 GAK62051.1 - 2.4e-15 56.8 0.0 3.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 CS domain DUF2057 PF09829.4 GAK62051.1 - 0.0067 16.1 3.5 0.0071 16.0 1.7 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) DUF3235 PF11574.3 GAK62051.1 - 0.21 11.8 4.9 5.4 7.3 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Glyco_hydro_67N PF03648.9 GAK62052.1 - 0.1 12.6 0.1 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus DUF896 PF05979.7 GAK62052.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Pkinase PF00069.20 GAK62053.1 - 1.3e-66 224.4 0.0 1.6e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62053.1 - 1.2e-28 99.8 0.0 1.7e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAK62053.1 - 4.4e-11 43.1 0.1 4.4e-11 43.1 0.1 4.1 5 1 0 5 5 5 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAK62053.1 - 4.1e-08 32.5 0.0 1.8e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 GAK62053.1 - 0.00019 21.2 0.1 0.0019 18.0 0.1 2.3 1 1 0 1 1 1 1 C2 domain APH PF01636.18 GAK62053.1 - 0.042 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 GAK62053.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 GAK62054.1 - 4.4e-14 51.8 0.0 1.8e-07 30.6 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK62054.1 - 3.7e-13 49.2 0.0 1e-08 35.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK62054.1 - 1.6e-06 27.8 0.1 0.002 17.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.3 GAK62054.1 - 0.094 11.2 0.2 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain SNARE PF05739.14 GAK62055.1 - 4.3e-16 58.3 1.7 4.3e-16 58.3 1.2 2.5 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 GAK62055.1 - 1.3e-15 57.3 4.2 2.7e-15 56.3 0.3 2.4 2 0 0 2 2 2 1 Syntaxin DUF1664 PF07889.7 GAK62055.1 - 0.032 14.0 2.4 0.19 11.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-18_N PF10496.4 GAK62055.1 - 0.038 13.8 0.8 0.3 10.9 0.1 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF2894 PF11445.3 GAK62055.1 - 0.059 13.6 4.0 0.12 12.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) FlaC_arch PF05377.6 GAK62055.1 - 0.1 12.4 1.9 0.27 11.1 0.2 2.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 GAK62055.1 - 0.11 12.9 3.2 1.6 9.1 0.1 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Lge1 PF11488.3 GAK62055.1 - 0.14 12.3 2.0 1 9.5 0.1 2.7 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 DUF848 PF05852.6 GAK62055.1 - 0.49 10.2 4.3 3.8 7.3 0.1 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) AAA_13 PF13166.1 GAK62055.1 - 0.77 8.1 5.9 0.5 8.7 1.4 1.9 2 0 0 2 2 2 0 AAA domain DUF148 PF02520.12 GAK62055.1 - 0.9 9.3 6.4 0.5 10.1 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function DUF148 Spectrin PF00435.16 GAK62055.1 - 1 9.7 4.6 4.2 7.7 0.2 3.3 2 1 0 3 3 3 0 Spectrin repeat BLOC1_2 PF10046.4 GAK62055.1 - 2.6 8.2 7.3 2.5 8.3 0.4 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 GAK62055.1 - 4.9 6.9 9.7 1.3 8.8 0.1 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DNA_pol_B_thumb PF14791.1 GAK62056.1 - 1.3e-19 69.6 0.0 2.7e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 GAK62056.1 - 3.3e-09 36.7 0.0 1.1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 GAK62056.1 - 3.4e-08 33.5 0.1 1.5e-07 31.4 0.1 2.2 1 1 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 GAK62056.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Abhydrolase_5 PF12695.2 GAK62057.1 - 0.00039 20.1 0.1 0.0019 17.9 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK62057.1 - 0.0024 17.8 1.2 0.0067 16.3 0.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAK62057.1 - 0.13 11.7 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ABC_tran PF00005.22 GAK62058.1 - 1.7e-35 122.3 0.0 2e-34 118.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 GAK62058.1 - 1.4e-32 113.2 6.7 1.7e-32 112.9 4.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 GAK62058.1 - 5.4e-07 29.8 0.0 0.016 15.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 GAK62058.1 - 1.7e-05 24.1 0.1 0.0018 17.5 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 GAK62058.1 - 0.00078 19.6 0.0 0.0074 16.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK62058.1 - 0.006 16.5 0.0 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 GAK62058.1 - 0.0099 15.3 0.1 0.026 14.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 GAK62058.1 - 0.014 15.2 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAK62058.1 - 0.023 14.8 0.0 0.18 11.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAK62058.1 - 0.036 13.2 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAK62058.1 - 0.052 14.3 0.0 0.14 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 GAK62058.1 - 0.055 13.3 0.2 0.56 10.1 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 GAK62058.1 - 0.076 12.8 0.1 0.4 10.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 GAK62058.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 GAK62060.1 - 4.5e-91 305.4 0.0 5.3e-91 305.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II 2-oxoacid_dh PF00198.18 GAK62062.1 - 1.2e-78 263.5 0.2 1.6e-78 263.1 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAK62062.1 - 2.9e-20 71.6 1.9 4.6e-20 71.0 0.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 GAK62062.1 - 4.7e-18 64.5 0.4 1.3e-17 63.0 0.3 1.9 1 0 0 1 1 1 1 e3 binding domain SR-25 PF10500.4 GAK62062.1 - 0.0026 17.2 8.2 0.0026 17.2 5.7 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 GAK62062.1 - 0.0031 17.5 1.4 0.0031 17.5 1.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF755) RAP1 PF07218.6 GAK62062.1 - 7.9 4.4 6.4 12 3.8 4.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WD40 PF00400.27 GAK62064.1 - 2.5e-63 207.8 16.6 1.5e-10 40.5 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat LisH PF08513.6 GAK62064.1 - 1.2e-06 28.0 0.3 2.2e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 GAK62064.1 - 0.00047 19.9 0.0 0.048 13.3 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAK62064.1 - 0.0072 14.5 0.4 0.67 8.0 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 GAK62064.1 - 0.027 13.9 0.1 7 6.2 0.0 4.1 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 GAK62064.1 - 0.06 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_S7 PF00177.16 GAK62065.1 - 2.1e-40 137.7 1.0 2.7e-40 137.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Lactamase_B PF00753.22 GAK62067.1 - 9.8e-24 84.0 0.9 1.6e-23 83.3 0.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily LRR_6 PF13516.1 GAK62067.1 - 1.7e-10 39.8 0.2 4.8 7.5 0.0 7.0 7 0 0 7 7 7 2 Leucine Rich repeat F-box-like PF12937.2 GAK62067.1 - 1.9e-07 30.6 0.1 6.2e-07 29.0 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 GAK62067.1 - 1.8e-05 24.1 6.6 8.3 7.1 0.1 7.3 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 GAK62067.1 - 0.00045 19.8 7.8 12 6.3 0.1 6.4 6 0 0 6 6 6 1 Leucine Rich Repeat F-box PF00646.28 GAK62067.1 - 0.0022 17.5 5.6 0.082 12.5 0.7 3.6 2 1 0 2 2 2 1 F-box domain LRR_8 PF13855.1 GAK62067.1 - 0.034 13.9 2.0 1.6 8.5 0.0 3.8 5 0 0 5 5 5 0 Leucine rich repeat Lactamase_B_2 PF12706.2 GAK62067.1 - 0.035 13.6 0.3 0.068 12.7 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain A_deaminase PF00962.17 GAK62068.1 - 1.4e-36 126.0 0.1 2.3e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Cpn60_TCP1 PF00118.19 GAK62069.1 - 1.2e-147 492.4 0.5 1.4e-147 492.2 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PIP5K PF01504.13 GAK62070.1 - 1.1e-62 211.4 0.0 2e-62 210.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 GAK62070.1 - 2.4e-22 79.2 0.0 3.9e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 GAK62070.1 - 1.4e-15 56.9 10.4 3.5e-15 55.6 7.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 GAK62070.1 - 0.39 10.6 6.1 0.27 11.1 2.5 2.0 2 0 0 2 2 2 0 IBR domain Nop53 PF07767.6 GAK62070.1 - 3.7 6.4 13.8 6.9 5.5 9.6 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TRAP_alpha PF03896.11 GAK62070.1 - 4.5 6.1 8.4 9.5 5.1 5.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DPBB_1 PF03330.13 GAK62071.1 - 2.3e-06 27.4 0.8 6.4e-06 26.0 0.5 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SOG2 PF10428.4 GAK62071.1 - 0.0011 17.7 7.9 0.0011 17.7 5.5 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Barwin PF00967.12 GAK62071.1 - 0.002 17.7 0.1 0.0046 16.6 0.1 1.6 1 1 0 1 1 1 1 Barwin family DUF2217 PF10265.4 GAK62071.1 - 0.11 11.1 6.9 0.18 10.5 4.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MSP1_C PF07462.6 GAK62071.1 - 0.55 8.5 6.0 0.68 8.2 4.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Macoilin PF09726.4 GAK62071.1 - 7.8 4.6 16.3 10 4.2 11.3 1.1 1 0 0 1 1 1 0 Transmembrane protein NIF PF03031.13 GAK62072.1 - 8.3e-22 77.5 0.0 3e-21 75.7 0.0 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 GAK62072.1 - 0.00099 19.3 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PTCB-BRCT PF12738.2 GAK62072.1 - 0.003 17.3 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain MMR_HSR1 PF01926.18 GAK62073.1 - 1.8e-14 53.7 0.0 1.6e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK62073.1 - 0.00012 21.4 0.0 0.00053 19.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAK62073.1 - 0.0014 18.5 0.1 0.007 16.2 0.1 2.1 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 GAK62073.1 - 0.015 15.7 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 GAK62073.1 - 0.036 13.2 0.1 0.077 12.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 GAK62073.1 - 0.2 10.6 0.0 0.48 9.3 0.0 1.6 1 0 0 1 1 1 0 Septin PNP_UDP_1 PF01048.15 GAK62074.1 - 4.1e-37 127.3 0.4 5e-37 127.1 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily SNF2_N PF00176.18 GAK62075.1 - 3.4e-64 216.5 0.0 6e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 GAK62075.1 - 3.7e-13 49.3 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 GAK62075.1 - 1.4e-08 34.5 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 GAK62075.1 - 0.00015 21.3 0.4 0.00051 19.6 0.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK62075.1 - 0.00015 21.4 0.5 0.00015 21.4 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAK62075.1 - 0.00027 20.7 1.3 0.00078 19.2 0.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAK62075.1 - 0.0022 17.9 1.1 0.0022 17.9 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 GAK62075.1 - 0.036 13.8 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 GAK62075.1 - 0.048 13.3 0.0 0.21 11.3 0.0 2.1 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 GAK62075.1 - 0.12 12.1 1.3 9.7 6.1 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon CS PF04969.11 GAK62076.1 - 0.0024 18.3 0.0 0.019 15.5 0.0 2.1 2 0 0 2 2 2 1 CS domain YmdB PF13277.1 GAK62076.1 - 0.039 12.9 0.6 0.081 11.9 0.2 1.6 2 0 0 2 2 2 0 YmdB-like protein DUF883 PF05957.8 GAK62077.1 - 1.3e-06 28.6 36.6 0.021 15.2 1.8 4.3 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) AF0941-like PF14591.1 GAK62077.1 - 0.035 14.1 0.4 0.19 11.8 0.0 2.2 2 1 1 3 3 3 0 AF0941-like ApoO PF09769.4 GAK62077.1 - 0.058 13.0 4.1 0.61 9.7 0.5 2.5 2 0 0 2 2 2 0 Apolipoprotein O Phage_Coat_Gp8 PF05371.7 GAK62077.1 - 0.12 11.9 0.3 0.12 11.9 0.2 4.8 5 1 1 6 6 6 0 Phage major coat protein, Gp8 Apolipoprotein PF01442.13 GAK62077.1 - 0.24 10.8 21.0 0.59 9.6 1.2 2.4 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain YtxH PF12732.2 GAK62077.1 - 0.25 11.7 32.4 1.5e+04 -15.3 22.4 4.7 1 1 0 1 1 1 0 YtxH-like protein DivIVA PF05103.8 GAK62077.1 - 1.6 8.7 43.6 0.087 12.8 6.6 4.5 1 1 3 4 4 4 0 DivIVA protein ISG65-75 PF11727.3 GAK62077.1 - 8.2 5.3 30.0 1.8 7.5 6.4 2.6 1 1 2 3 3 3 0 Invariant surface glycoprotein Chlorosome_CsmC PF11098.3 GAK62077.1 - 9 6.0 33.0 3.1 7.5 5.1 4.2 1 1 3 4 4 4 0 Chlorosome envelope protein C HA2 PF04408.18 GAK62078.1 - 6.4e-19 67.8 2.7 1.2e-18 66.9 0.1 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAK62078.1 - 2.7e-13 49.5 0.1 8.5e-13 47.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 GAK62078.1 - 4.2e-11 42.6 0.0 1.3e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 GAK62078.1 - 1.9e-10 40.5 0.0 3.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAK62078.1 - 7.6e-08 32.5 0.4 3e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAK62078.1 - 0.018 14.7 0.1 0.018 14.7 0.1 1.9 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 GAK62078.1 - 0.029 13.2 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 GAK62078.1 - 0.043 12.9 0.0 0.098 11.7 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 GAK62078.1 - 0.17 12.1 0.0 0.17 12.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain CDC45 PF02724.9 GAK62079.1 - 0.95 7.4 4.4 1.7 6.6 3.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Sas10_Utp3 PF04000.10 GAK62080.1 - 2.6e-22 78.7 0.1 5.1e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ydc2-catalyt PF09159.5 GAK62080.1 - 0.29 10.5 5.3 0.43 10.0 3.7 1.3 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Ustilago_mating PF05722.7 GAK62081.1 - 1.2e-94 316.7 4.1 1.9e-94 316.2 2.8 1.3 1 0 0 1 1 1 1 Ustilago B locus mating-type protein Homeobox_KN PF05920.6 GAK62081.1 - 1.2e-15 56.9 0.6 5.1e-15 54.9 0.4 2.2 1 1 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAK62082.1 - 7.7e-13 47.8 1.1 1.1e-12 47.3 0.2 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 GAK62082.1 - 0.00035 20.2 0.1 0.00072 19.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain NARP1 PF12569.3 GAK62083.1 - 4.4e-182 606.4 4.6 7.8e-182 605.6 3.2 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 GAK62083.1 - 2.1e-12 45.9 13.9 4.5e-06 26.1 0.1 8.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAK62083.1 - 1.1e-11 44.8 24.4 0.014 15.7 0.0 9.5 6 2 3 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAK62083.1 - 1.3e-09 37.2 2.9 2.3e-05 23.8 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAK62083.1 - 3.2e-09 36.3 8.4 7.3e-05 22.3 0.0 6.1 5 1 2 7 7 7 3 TPR repeat TPR_16 PF13432.1 GAK62083.1 - 1.2e-08 35.4 43.6 0.19 12.4 0.0 11.6 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAK62083.1 - 1.8e-08 34.2 35.2 0.75 10.6 0.0 11.6 10 3 3 13 13 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAK62083.1 - 1.8e-07 30.3 9.8 0.00022 20.7 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAK62083.1 - 3.7e-07 29.9 23.9 0.007 16.2 0.0 6.9 7 1 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 GAK62083.1 - 8e-06 25.9 2.7 0.97 9.6 0.0 6.2 7 0 0 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 GAK62083.1 - 1.9e-05 24.6 31.6 0.3 11.6 0.5 8.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAK62083.1 - 0.00017 21.1 5.0 0.075 12.8 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAK62083.1 - 0.0011 18.7 10.8 1.1 9.1 0.5 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAK62083.1 - 0.0019 18.5 19.0 2.8 8.6 0.0 9.5 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAK62083.1 - 0.0053 16.8 2.4 50 4.4 0.1 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat MerR_2 PF13591.1 GAK62083.1 - 0.034 13.7 0.3 0.26 10.9 0.1 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein TPR_10 PF13374.1 GAK62083.1 - 0.14 12.1 12.1 0.27 11.2 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat SSP160 PF06933.6 GAK62083.1 - 1.2 7.0 4.6 1.9 6.3 3.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ion_trans PF00520.26 GAK62084.1 - 9.5e-05 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Ion transport protein SUR7 PF06687.7 GAK62085.1 - 2.9e-26 92.3 9.1 3.9e-26 91.9 6.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family MMPL PF03176.10 GAK62085.1 - 0.25 10.0 3.1 0.46 9.1 2.1 1.3 1 0 0 1 1 1 0 MMPL family VMA21 PF09446.5 GAK62085.1 - 0.34 10.8 2.1 0.72 9.8 1.5 1.4 1 0 0 1 1 1 0 VMA21-like domain Claudin_2 PF13903.1 GAK62085.1 - 0.44 10.2 11.8 0.92 9.1 7.8 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 GAK62085.1 - 4.8 6.3 6.5 9.7 5.3 4.5 1.5 1 0 0 1 1 1 0 Clc-like ANTH PF07651.11 GAK62086.1 - 3.4e-75 252.3 0.2 3.4e-75 252.3 0.2 2.4 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 GAK62086.1 - 1.1e-62 210.4 8.7 1.1e-62 210.4 6.0 4.4 4 1 0 4 4 4 2 I/LWEQ domain ENTH PF01417.15 GAK62086.1 - 1.5e-09 37.7 0.3 1.6e-08 34.4 0.0 2.9 2 0 0 2 2 2 1 ENTH domain ATP-synt_ab PF00006.20 GAK62086.1 - 0.071 12.5 0.8 0.16 11.4 0.6 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PCI PF01399.22 GAK62087.1 - 5.9e-16 58.7 0.0 2.2e-15 56.8 0.0 2.1 1 0 0 1 1 1 1 PCI domain DUF1510 PF07423.6 GAK62087.1 - 0.0051 16.2 7.0 0.0091 15.3 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 GAK62087.1 - 0.023 14.1 12.1 0.053 12.9 8.4 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 GAK62087.1 - 0.035 11.8 5.6 0.051 11.3 3.9 1.2 1 0 0 1 1 1 0 Ycf1 Cnd1_N PF12922.2 GAK62087.1 - 0.047 13.3 3.7 6.7 6.3 0.0 2.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term GAGA_bind PF06217.7 GAK62087.1 - 0.51 10.2 6.1 0.85 9.5 4.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 GAK62087.1 - 0.99 8.5 7.4 1.8 7.7 5.1 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Vfa1 PF08432.5 GAK62087.1 - 3.2 7.7 18.2 0.23 11.4 8.8 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 LIN37 PF15306.1 GAK62087.1 - 4.9 7.1 11.9 11 5.9 0.1 2.5 2 0 0 2 2 2 0 LIN37 Pkinase PF00069.20 GAK62088.1 - 3.3e-39 134.5 0.0 4.2e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62088.1 - 6.3e-16 58.2 0.0 8.4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK62088.1 - 5.2e-06 26.3 0.1 0.003 17.3 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAK62088.1 - 0.018 13.8 0.1 0.032 13.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PFU PF09070.6 GAK62088.1 - 0.089 12.8 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) NAD_binding_6 PF08030.7 GAK62089.1 - 0.00064 19.6 0.1 0.0013 18.6 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 GAK62089.1 - 0.0024 18.4 0.0 0.0089 16.5 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAK62089.1 - 0.019 15.0 0.0 0.11 12.6 0.0 2.1 1 1 1 2 2 2 0 Oxidoreductase FAD-binding domain Drc1-Sld2 PF11719.3 GAK62090.1 - 7.9e-07 28.5 27.2 8.4e-07 28.4 14.8 2.9 2 1 0 2 2 2 1 DNA replication and checkpoint protein Ribosomal_L30 PF00327.15 GAK62092.1 - 6.8e-12 44.7 0.1 1.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e zf-RING_2 PF13639.1 GAK62093.1 - 0.0014 18.3 0.1 0.0032 17.2 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAK62093.1 - 0.003 17.2 0.0 0.003 17.2 0.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAK62093.1 - 0.0093 15.6 1.6 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger RabGAP-TBC PF00566.13 GAK62094.1 - 8.6e-37 126.6 0.0 1.2e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 GAK62095.1 - 2.2e-60 204.0 0.0 3e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62095.1 - 1.8e-24 86.2 0.0 2.7e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK62095.1 - 2.5e-05 23.3 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK62095.1 - 0.017 14.8 0.0 0.05 13.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAK62095.1 - 0.039 13.5 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tannase PF07519.6 GAK62096.1 - 1.5e-81 274.5 1.8 1.3e-80 271.4 1.2 2.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 GAK62096.1 - 1.8e-05 24.5 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK62096.1 - 0.0027 16.9 0.0 0.66 9.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAK62096.1 - 0.03 14.2 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Glyco_hydro_38 PF01074.17 GAK62097.1 - 1.5e-82 276.9 1.1 2.3e-82 276.3 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAK62097.1 - 7e-55 186.6 0.0 1.1e-54 186.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAK62097.1 - 5.8e-27 93.7 0.0 2.1e-26 91.9 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Con-6 PF10346.4 GAK62097.1 - 8.4e-07 28.2 0.1 1.6e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Conidiation protein 6 RCC1 PF00415.13 GAK62098.1 - 1.3e-34 118.1 14.7 9.4e-06 25.7 0.0 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAK62098.1 - 1.3e-28 97.8 16.2 1.3e-06 27.8 0.1 6.8 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat NAD_Gly3P_dh_C PF07479.9 GAK62099.1 - 5.4e-50 168.9 0.0 8.4e-50 168.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 GAK62099.1 - 3.2e-49 166.6 0.1 6.7e-49 165.6 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 GAK62099.1 - 0.00043 20.6 0.1 0.0044 17.4 0.1 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sec2p PF06428.6 GAK62101.1 - 1.3e-15 57.0 9.0 1.3e-15 57.0 6.2 3.0 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF948 PF06103.6 GAK62101.1 - 0.046 13.5 4.7 3.1 7.7 0.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AroM PF07302.6 GAK62101.1 - 0.065 12.5 1.3 0.19 11.0 0.2 2.0 2 0 0 2 2 2 0 AroM protein Baculo_PEP_C PF04513.7 GAK62101.1 - 6 6.6 7.4 3 7.6 1.3 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec7 PF01369.15 GAK62102.1 - 1.1e-36 126.3 0.0 2.4e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 GAK62102.1 - 3.9e-30 104.4 0.0 9.3e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAK62102.1 - 0.0022 18.1 0.0 0.0061 16.7 0.0 1.8 1 0 0 1 1 1 1 PH domain zf-C2H2 PF00096.21 GAK62103.1 - 7.1e-09 35.5 14.8 0.0003 20.9 2.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK62103.1 - 0.0022 18.2 11.9 0.0037 17.4 0.9 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 GAK62103.1 - 0.032 14.1 3.2 1.1 9.2 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 GAK62103.1 - 0.04 14.2 11.8 0.31 11.4 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PI3K_1B_p101 PF10486.4 GAK62103.1 - 0.67 7.4 1.9 1.1 6.7 1.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-C2HC_2 PF13913.1 GAK62103.1 - 6 6.6 7.3 5 6.9 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NAD_kinase PF01513.16 GAK62105.1 - 2.5e-67 226.6 0.0 5.5e-67 225.5 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase GDA1_CD39 PF01150.12 GAK62106.1 - 3.6e-85 286.0 0.0 5.2e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 GAK62106.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family P5CR_dimer PF14748.1 GAK62107.1 - 6e-38 129.1 2.7 6e-38 129.1 1.9 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 GAK62107.1 - 1.6e-13 50.9 0.7 5.3e-12 46.0 0.5 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 GAK62108.1 - 1.2e-44 151.6 0.1 3.7e-44 150.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAK62108.1 - 8.4e-09 35.2 0.5 2.7e-08 33.6 0.1 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAK62108.1 - 6.7e-08 32.6 0.0 1.6e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 GAK62108.1 - 4.3e-07 30.1 0.5 0.00033 20.7 0.3 3.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAK62108.1 - 8.7e-07 29.1 0.1 3.9e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 GAK62108.1 - 4e-06 25.9 0.1 1.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 GAK62108.1 - 0.0002 21.3 0.4 0.00081 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAK62108.1 - 0.00038 19.5 0.0 0.00089 18.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 GAK62108.1 - 0.00042 20.0 0.2 0.0029 17.3 0.0 2.4 3 0 0 3 3 2 1 NTPase AAA_19 PF13245.1 GAK62108.1 - 0.00046 19.8 0.1 0.0013 18.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 GAK62108.1 - 0.00054 19.8 0.0 0.0017 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 GAK62108.1 - 0.00065 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAK62108.1 - 0.00077 19.7 0.2 0.015 15.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 GAK62108.1 - 0.00096 18.8 0.1 0.034 13.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 GAK62108.1 - 0.0011 19.7 0.0 0.0049 17.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 GAK62108.1 - 0.0014 17.3 0.0 0.0028 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 GAK62108.1 - 0.0018 18.4 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Arch_ATPase PF01637.13 GAK62108.1 - 0.0027 17.4 0.7 0.09 12.4 0.0 3.0 2 1 0 3 3 3 1 Archaeal ATPase AAA_33 PF13671.1 GAK62108.1 - 0.0035 17.2 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAK62108.1 - 0.0057 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 GAK62108.1 - 0.0059 16.2 0.0 0.02 14.5 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 GAK62108.1 - 0.0059 15.7 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 GAK62108.1 - 0.0064 16.0 1.6 0.025 14.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAK62108.1 - 0.0075 15.3 0.4 0.015 14.4 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin IstB_IS21 PF01695.12 GAK62108.1 - 0.0082 15.5 0.3 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 GAK62108.1 - 0.013 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAK62108.1 - 0.018 15.3 3.2 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 GAK62108.1 - 0.022 14.3 0.0 0.06 12.9 0.0 1.7 2 0 0 2 2 1 0 Bacterial dnaA protein AAA_25 PF13481.1 GAK62108.1 - 0.049 13.0 0.1 0.049 13.0 0.1 2.6 2 1 1 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 GAK62108.1 - 0.053 13.5 0.2 0.97 9.4 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 GAK62108.1 - 0.053 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.11 GAK62108.1 - 0.058 12.1 0.2 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.21 GAK62108.1 - 0.064 12.7 0.2 1.4 8.3 0.0 2.8 3 1 0 3 3 3 0 Sigma-54 interaction domain KaiC PF06745.8 GAK62108.1 - 0.12 11.4 0.6 0.53 9.3 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_29 PF13555.1 GAK62108.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2968 PF11180.3 GAK62108.1 - 0.5 9.7 5.9 0.96 8.8 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_10 PF12846.2 GAK62108.1 - 1.2 8.5 3.6 1.4 8.2 0.1 2.6 3 1 1 4 4 4 0 AAA-like domain DUF2076 PF09849.4 GAK62109.1 - 1e-09 38.8 12.2 1.2e-09 38.5 8.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 GAK62109.1 - 0.00064 19.5 5.9 0.00095 19.0 4.1 1.3 1 0 0 1 1 1 1 CHCH domain Nucleoporin_FG PF13634.1 GAK62109.1 - 0.18 12.0 17.3 0.26 11.5 12.0 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region Pet191_N PF10203.4 GAK62109.1 - 0.78 9.8 3.8 1.4 8.9 0.2 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PAT1 PF09770.4 GAK62109.1 - 9.3 4.3 13.0 9.9 4.2 9.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SET PF00856.23 GAK62112.1 - 1.5e-07 31.8 0.0 1.5e-07 31.8 0.0 4.2 4 1 0 4 4 4 1 SET domain zf-rbx1 PF12678.2 GAK62113.1 - 1.5e-14 53.8 0.8 2.6e-14 53.0 0.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAK62113.1 - 1.8e-11 43.6 6.2 4.8e-11 42.3 4.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAK62113.1 - 1.6e-06 27.6 2.9 2.9e-06 26.8 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK62113.1 - 2.5e-06 27.0 1.7 5.6e-06 25.9 1.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAK62113.1 - 4.2e-06 26.5 0.2 8.1e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 GAK62113.1 - 1e-05 25.4 2.0 1e-05 25.4 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK62113.1 - 4.8e-05 22.9 5.3 0.00044 19.8 3.9 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAK62113.1 - 0.0005 19.7 1.9 0.0012 18.4 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAK62113.1 - 0.002 17.9 2.5 0.003 17.3 1.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 GAK62113.1 - 0.0033 17.3 0.5 0.0065 16.4 0.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 GAK62113.1 - 0.75 9.4 2.3 1 8.9 0.6 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FliD_N PF02465.13 GAK62113.1 - 1.8 9.0 7.9 17 5.8 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF1819 PF08849.6 GAK62114.1 - 0.047 13.0 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Rpr2 PF04032.11 GAK62114.1 - 0.26 11.1 3.0 0.26 11.1 0.6 2.0 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3446 PF11928.3 GAK62114.1 - 0.27 11.4 5.8 0.62 10.2 3.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) CENP-F_leu_zip PF10473.4 GAK62115.1 - 1.1 9.1 51.0 3.7 7.3 9.0 3.5 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 GAK62115.1 - 5.4 7.0 41.4 9.8 6.2 9.7 4.4 2 1 2 4 4 4 0 DivIVA protein TPR_MLP1_2 PF07926.7 GAK62115.1 - 7.3 6.3 50.3 1.6 8.4 8.2 4.1 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Sec7_N PF12783.2 GAK62116.1 - 8.3e-34 116.4 0.6 3e-33 114.6 0.4 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAK62116.1 - 0.00048 19.5 0.6 0.021 14.3 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Mito_carr PF00153.22 GAK62118.1 - 7.9e-17 60.7 5.1 9.2e-06 25.2 0.0 6.1 5 1 0 5 5 5 5 Mitochondrial carrier protein HrpJ PF07201.6 GAK62118.1 - 6.4 6.7 7.9 1.1 9.3 0.1 2.6 3 0 0 3 3 3 0 HrpJ-like domain Cupin_5 PF06172.6 GAK62121.1 - 1.1e-18 67.4 0.0 1.4e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) NYN PF01936.13 GAK62122.1 - 2.9e-26 92.5 0.0 5.9e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 NYN domain SLH PF00395.15 GAK62122.1 - 0.058 13.1 2.4 3.3 7.5 0.0 3.4 3 0 0 3 3 3 0 S-layer homology domain COPI_assoc PF08507.5 GAK62124.1 - 0.08 12.6 0.3 0.81 9.3 0.0 2.1 2 0 0 2 2 2 0 COPI associated protein SPOR PF05036.8 GAK62124.1 - 0.082 13.0 1.8 0.11 12.6 0.2 1.9 2 0 0 2 2 2 0 Sporulation related domain WD40 PF00400.27 GAK62125.1 - 5.2e-26 89.5 13.0 1e-08 34.7 0.3 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAK62125.1 - 0.019 13.2 0.0 0.82 7.8 0.0 2.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Lgl_C PF08596.5 GAK62125.1 - 0.057 11.8 0.2 0.1 11.0 0.2 1.3 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal CUE PF02845.11 GAK62126.1 - 1.7e-12 46.5 0.0 2.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Sec6 PF06046.8 GAK62126.1 - 0.0035 15.5 0.0 0.0049 15.0 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Fungal_trans PF04082.13 GAK62127.1 - 2.6e-26 92.0 0.0 5.8e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK62127.1 - 8.9e-10 38.3 6.2 8.9e-10 38.3 4.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NYD-SP28_assoc PF14775.1 GAK62127.1 - 0.28 10.9 1.6 0.78 9.4 0.5 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Sugar_tr PF00083.19 GAK62128.1 - 1.3e-30 106.4 40.8 1.2e-26 93.3 18.8 3.3 2 1 2 4 4 4 2 Sugar (and other) transporter MFS_1 PF07690.11 GAK62128.1 - 4.6e-26 91.3 48.3 5.4e-24 84.5 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nucleoside_tran PF01733.13 GAK62128.1 - 0.00011 21.5 0.0 0.00034 19.8 0.0 1.8 2 0 0 2 2 2 1 Nucleoside transporter Zn_clus PF00172.13 GAK62130.1 - 2.7e-06 27.1 9.5 2.7e-06 27.1 6.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK62130.1 - 4.5e-05 22.4 0.1 0.0003 19.7 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_delta_4 PF04081.8 GAK62132.1 - 1.6e-19 70.3 0.1 2.5e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 ATP_bind_1 PF03029.12 GAK62133.1 - 1.8e-64 217.5 0.0 4.1e-55 186.9 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAK62133.1 - 0.042 14.6 3.5 0.085 13.6 0.4 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 GAK62133.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 GAK62133.1 - 0.11 12.0 0.0 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAK62133.1 - 0.14 11.8 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain UQ_con PF00179.21 GAK62134.1 - 8.5e-42 141.9 0.0 1.1e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 GAK62134.1 - 5.9e-23 80.2 0.8 1e-22 79.4 0.6 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 GAK62134.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Prok-E2_E PF14462.1 GAK62134.1 - 0.073 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E ArfGap PF01412.13 GAK62135.1 - 1.5e-32 111.8 0.1 1.5e-32 111.8 0.1 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf A2L_zn_ribbon PF08792.5 GAK62135.1 - 0.018 14.5 1.0 0.035 13.5 0.7 1.5 1 1 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.2 GAK62135.1 - 0.15 11.9 0.3 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon NOT2_3_5 PF04153.13 GAK62136.1 - 2.5e-38 131.0 2.3 2.5e-38 131.0 1.6 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family zf-C3HC4_3 PF13920.1 GAK62139.1 - 5.4e-09 35.5 4.1 4.6e-07 29.4 0.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK62139.1 - 3.7e-08 33.0 5.0 2e-07 30.6 0.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAK62139.1 - 4.5e-08 32.9 1.7 4.5e-08 32.9 1.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK62139.1 - 1.4e-07 31.0 0.7 1.4e-07 31.0 0.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK62139.1 - 1.4e-05 24.7 6.2 1.5e-05 24.6 1.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAK62139.1 - 0.00032 20.3 0.7 0.00032 20.3 0.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAK62139.1 - 0.0019 18.0 2.7 0.0019 18.0 1.8 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING EF-hand_1 PF00036.27 GAK62140.1 - 5.7e-27 90.9 7.9 2.8e-08 32.4 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 GAK62140.1 - 6.5e-24 83.8 3.8 2e-14 53.4 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAK62140.1 - 5e-22 75.7 1.9 3.3e-06 26.5 0.1 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 GAK62140.1 - 5.1e-15 54.8 5.7 0.00047 19.7 0.1 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 GAK62140.1 - 2e-14 52.1 8.5 9.7e-05 21.5 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 GAK62140.1 - 7.9e-11 41.6 2.3 0.0029 17.3 0.0 4.0 2 1 2 4 4 4 4 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAK62140.1 - 6.8e-05 22.6 1.3 0.033 14.0 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 GAK62140.1 - 0.00018 21.5 1.7 0.18 11.8 0.0 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 GAK62140.1 - 0.018 15.1 0.0 1.4 8.9 0.0 2.8 3 1 1 4 4 4 0 EF hand EF-hand_10 PF14788.1 GAK62140.1 - 0.022 14.4 1.4 26 4.5 0.0 4.0 4 0 0 4 4 4 0 EF hand Mad3_BUB1_II PF08171.6 GAK62140.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 S10_plectin PF03501.10 GAK62140.1 - 0.05 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain DUF1679 PF07914.6 GAK62140.1 - 0.057 12.0 0.6 1 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_3 PF09069.6 GAK62140.1 - 0.099 12.7 0.2 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 EF-hand ETF PF01012.16 GAK62141.1 - 2.5e-37 128.1 0.1 3.3e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Usp PF00582.21 GAK62141.1 - 0.11 12.7 1.7 0.15 12.2 0.5 1.8 2 0 0 2 2 2 0 Universal stress protein family Glycos_transf_3 PF00591.16 GAK62142.1 - 1e-75 254.4 0.0 1.6e-70 237.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain TarH PF02203.10 GAK62142.1 - 0.021 14.6 0.3 0.037 13.8 0.2 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue TPPII PF12580.3 GAK62143.1 - 1.3e-54 184.4 0.2 1.3e-54 184.4 0.1 1.7 2 0 0 2 2 2 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.17 GAK62143.1 - 3.8e-41 141.0 0.0 2.4e-31 108.9 0.1 2.6 1 1 1 2 2 2 2 Subtilase family RRM_1 PF00076.17 GAK62144.1 - 3.2e-57 190.0 0.1 3.5e-17 61.7 0.0 6.9 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK62144.1 - 2.1e-43 146.1 0.1 3.2e-10 39.8 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK62144.1 - 5.8e-18 64.4 0.0 0.00013 21.7 0.0 6.3 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 GAK62144.1 - 3.5 5.3 4.3 6 4.5 3.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family START PF01852.14 GAK62145.1 - 6.2e-05 22.4 0.0 0.00013 21.4 0.0 1.6 1 1 0 1 1 1 1 START domain Nucleoside_tran PF01733.13 GAK62146.1 - 3.4e-31 108.5 4.8 3.7e-31 108.4 1.1 2.5 2 1 0 2 2 2 1 Nucleoside transporter Tetraspannin PF00335.15 GAK62146.1 - 0.0022 17.3 4.5 0.0039 16.4 0.0 2.5 2 0 0 2 2 2 1 Tetraspanin family BRO1 PF03097.13 GAK62147.1 - 2.9e-113 378.4 0.7 2.9e-113 378.4 0.5 2.3 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAK62147.1 - 6.4e-62 209.1 11.1 6.4e-62 209.1 7.7 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Med6 PF04934.9 GAK62149.1 - 1.7e-47 160.4 0.0 2.1e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component ATP-synt_C PF00137.16 GAK62150.1 - 1.5e-29 101.7 30.3 6.8e-18 64.3 8.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C AAA PF00004.24 GAK62152.1 - 8.7e-40 135.9 0.0 1.4e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAK62152.1 - 5e-07 29.0 0.1 1.5e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAK62152.1 - 2.1e-06 27.9 0.2 8.8e-05 22.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAK62152.1 - 7.7e-06 26.0 0.2 0.00076 19.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAK62152.1 - 8.5e-06 26.5 0.0 2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAK62152.1 - 9.8e-06 25.3 0.2 5.6e-05 22.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAK62152.1 - 4.4e-05 23.3 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAK62152.1 - 6.5e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAK62152.1 - 0.00012 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 GAK62152.1 - 0.00018 20.9 1.0 0.011 15.1 0.3 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAK62152.1 - 0.0003 20.2 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAK62152.1 - 0.00053 19.2 0.3 0.0018 17.4 0.2 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 GAK62152.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 GAK62152.1 - 0.00096 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 GAK62152.1 - 0.0014 18.2 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAK62152.1 - 0.0015 17.2 0.0 0.0026 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 GAK62152.1 - 0.0024 18.0 0.0 0.0061 16.7 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 GAK62152.1 - 0.0025 17.7 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAK62152.1 - 0.0026 16.9 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 GAK62152.1 - 0.0045 16.7 0.3 0.013 15.1 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_21 PF13304.1 GAK62152.1 - 0.006 16.5 0.4 0.77 9.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 GAK62152.1 - 0.0084 15.5 0.0 0.023 14.1 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 GAK62152.1 - 0.0097 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 GAK62152.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 1 0 1 1 1 0 Bacterial dnaA protein Guanylate_kin PF00625.16 GAK62152.1 - 0.014 14.8 0.0 0.042 13.2 0.0 1.8 3 0 0 3 3 1 0 Guanylate kinase KaiC PF06745.8 GAK62152.1 - 0.014 14.5 0.0 0.25 10.4 0.0 2.2 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 GAK62152.1 - 0.016 14.8 0.1 0.041 13.5 0.1 1.7 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.8 GAK62152.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.6 GAK62152.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 GAK62152.1 - 0.06 12.9 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 GAK62152.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase PhoH PF02562.11 GAK62152.1 - 0.074 12.2 0.2 0.15 11.2 0.2 1.5 1 1 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 GAK62152.1 - 0.08 12.5 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 GAK62152.1 - 0.08 12.6 0.0 1.3 8.6 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase CPT PF07931.7 GAK62152.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 GAK62152.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 GAK62152.1 - 0.2 10.3 0.0 0.33 9.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KAP_NTPase PF07693.9 GAK62152.1 - 0.22 10.4 0.8 1.6 7.6 0.1 2.0 1 1 1 2 2 2 0 KAP family P-loop domain Proteasome PF00227.21 GAK62153.1 - 4.8e-41 140.1 0.0 5.5e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ETC_C1_NDUFA4 PF04800.7 GAK62154.1 - 2.2e-34 117.3 0.1 3.7e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region RPAP1_C PF08620.5 GAK62155.1 - 1.4e-24 85.7 0.1 3.4e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 GAK62155.1 - 0.00044 19.7 0.5 0.0014 18.2 0.4 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 GAK62155.1 - 0.00069 19.4 0.2 2.2 8.5 0.0 3.4 2 0 0 2 2 2 2 HEAT repeat TFIID-18kDa PF02269.11 GAK62156.1 - 7.4e-14 51.3 0.2 6e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit FHA PF00498.21 GAK62157.1 - 1.6e-09 37.7 0.0 5.3e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 FHA domain C1_1 PF00130.17 GAK62159.1 - 0.14 11.8 5.5 0.27 10.9 3.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cupin_8 PF13621.1 GAK62161.1 - 1.1e-55 188.9 0.0 1.3e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain CRAL_TRIO PF00650.15 GAK62162.1 - 9.7e-34 116.1 0.0 1.7e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAK62162.1 - 6.9e-11 42.1 0.5 2.2e-10 40.5 0.3 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAK62162.1 - 1.2e-08 35.0 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain cobW PF02492.14 GAK62163.1 - 1.8e-49 167.5 4.2 2e-36 125.1 0.5 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.18 GAK62163.1 - 3.4e-24 85.2 0.2 1.5e-23 83.1 0.1 2.2 2 0 0 2 2 1 1 HIT domain CobW_C PF07683.9 GAK62163.1 - 2e-18 65.9 0.8 8.9e-14 50.9 0.1 2.8 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain DcpS_C PF11969.3 GAK62163.1 - 5.2e-05 23.4 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ArgK PF03308.11 GAK62163.1 - 0.00019 20.3 0.5 0.042 12.6 0.0 2.9 3 0 0 3 3 3 2 ArgK protein CwfJ_C_1 PF04677.10 GAK62163.1 - 0.0018 17.9 0.0 0.005 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MobB PF03205.9 GAK62163.1 - 0.0095 15.6 0.1 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 GAK62163.1 - 0.024 14.2 0.1 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 GTP_EFTU PF00009.22 GAK62163.1 - 0.027 13.8 0.0 8.8 5.7 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Sigma70_ner PF04546.8 GAK62163.1 - 0.033 13.7 7.5 3.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region AAA_16 PF13191.1 GAK62163.1 - 0.098 12.6 2.9 0.78 9.7 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain BATS PF06968.8 GAK62163.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain AAA_29 PF13555.1 GAK62163.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 GAK62163.1 - 0.14 12.2 0.1 0.83 9.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain CsbD PF05532.7 GAK62164.1 - 5.8e-21 73.9 20.8 6.6e-12 44.9 5.4 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 GAK62164.1 - 0.0001 22.3 0.8 0.00021 21.2 0.3 1.7 1 1 1 2 2 2 1 Heat shock protein 9/12 MucBP PF06458.7 GAK62164.1 - 0.036 14.6 2.9 0.046 14.3 2.0 1.1 1 0 0 1 1 1 0 MucBP domain DUF202 PF02656.10 GAK62165.1 - 1.8e-20 72.8 0.2 1.8e-20 72.8 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF202) SH3_2 PF07653.12 GAK62166.1 - 2.4e-07 30.1 0.0 4.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAK62166.1 - 8.5e-07 28.4 0.4 2.1e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 GAK62166.1 - 0.0016 17.7 0.1 0.041 13.2 0.1 2.6 1 1 0 1 1 1 1 SH3 domain Zn_clus PF00172.13 GAK62167.1 - 2.2e-06 27.4 12.0 4.9e-06 26.3 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK62167.1 - 3.7e-06 25.9 0.0 6.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mob1_phocein PF03637.12 GAK62169.1 - 4e-22 78.7 0.1 4e-22 78.7 0.0 1.8 2 0 0 2 2 2 1 Mob1/phocein family Zip PF02535.17 GAK62169.1 - 5.9 5.7 9.3 0.5 9.3 2.5 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Abhydrolase_6 PF12697.2 GAK62170.1 - 0.018 14.9 0.2 0.055 13.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family TFIIB PF00382.14 GAK62171.1 - 4.6e-31 106.4 4.6 2.8e-16 59.0 0.0 3.8 3 1 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 GAK62171.1 - 5.7e-28 96.9 4.2 5.7e-28 96.9 2.9 3.6 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 GAK62171.1 - 1e-09 37.5 0.7 2.2e-09 36.4 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 GAK62171.1 - 4.1e-05 23.1 0.1 0.081 12.4 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 GAK62171.1 - 0.00097 18.2 0.7 0.0019 17.3 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 GAK62171.1 - 0.21 11.4 0.8 0.5 10.2 0.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAK62171.1 - 0.21 11.1 2.5 0.77 9.3 1.8 1.9 1 1 0 1 1 1 0 zinc-ribbon domain PX PF00787.19 GAK62172.1 - 6.5e-16 58.1 0.2 2.2e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 PX domain NYD-SP28 PF14772.1 GAK62172.1 - 0.012 15.6 0.1 0.035 14.2 0.1 1.7 1 0 0 1 1 1 0 Sperm tail TelA PF05816.6 GAK62172.1 - 0.043 12.5 2.6 0.037 12.7 0.5 1.7 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) Homeobox_KN PF05920.6 GAK62173.1 - 6.2e-18 64.2 0.2 1.7e-17 62.8 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 GAK62173.1 - 1.6e-05 24.4 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain DUF3492 PF11997.3 GAK62174.1 - 0.91 9.0 3.3 2.4 7.6 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) PGM_PMM_I PF02878.11 GAK62175.1 - 1.7e-37 127.9 0.2 2.6e-37 127.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 GAK62175.1 - 1.6e-26 92.5 0.0 2.6e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 GAK62175.1 - 5e-16 58.9 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAK62175.1 - 2.8e-09 36.8 0.0 6.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain tRNA_int_endo PF01974.12 GAK62176.1 - 7e-11 41.7 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_end_N2 PF12928.2 GAK62176.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Pkinase PF00069.20 GAK62177.1 - 3e-71 239.6 0.0 3.9e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62177.1 - 3.2e-31 108.3 0.0 4.4e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAK62177.1 - 5.3e-13 49.2 2.3 5.3e-13 49.2 1.6 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAK62177.1 - 0.0025 16.8 0.0 0.0046 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK62177.1 - 0.08 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.16 GAK62178.1 - 6.9e-05 22.7 3.2 8.2e-05 22.4 1.4 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAK62178.1 - 0.0055 16.4 4.0 0.0099 15.6 1.5 2.2 2 0 0 2 2 2 1 Basic region leucine zipper HeH PF12949.2 GAK62178.1 - 0.0095 15.4 0.2 0.019 14.4 0.2 1.5 1 0 0 1 1 1 1 HeH/LEM domain Herpes_BLRF2 PF05812.7 GAK62178.1 - 0.021 14.6 0.0 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF508 PF04370.7 GAK62178.1 - 0.24 11.0 1.2 0.53 9.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Rad60-SLD PF11976.3 GAK62179.1 - 1.2e-05 24.8 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Spt5_N PF11942.3 GAK62179.1 - 0.7 10.5 15.2 1.1 9.8 3.2 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Peptidase_S24 PF00717.18 GAK62180.1 - 2.9e-09 36.4 0.2 9.6e-08 31.5 0.0 2.1 1 1 1 2 2 2 2 Peptidase S24-like SCF PF02404.10 GAK62181.1 - 0.27 10.4 0.0 0.27 10.4 0.0 3.0 3 1 0 3 3 3 0 Stem cell factor Med16 PF11635.3 GAK62183.1 - 0.74 7.6 4.7 3.3 5.5 3.3 1.9 1 1 0 1 1 1 0 Mediator complex subunit 16 F-box-like PF12937.2 GAK62184.1 - 0.0083 15.8 0.4 0.047 13.4 0.0 2.6 3 1 0 3 3 3 1 F-box-like zf-CCHC_6 PF15288.1 GAK62184.1 - 0.14 11.8 1.5 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Zinc knuckle MFS_1 PF07690.11 GAK62185.1 - 2.2e-31 108.8 49.2 3.9e-31 108.0 34.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK62185.1 - 3.4e-08 32.4 33.7 4.5e-05 22.2 8.5 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAK62185.1 - 0.00036 20.2 0.2 0.00036 20.2 0.2 3.4 4 0 0 4 4 4 1 MFS_1 like family Abhydrolase_6 PF12697.2 GAK62186.1 - 2.7e-32 112.4 6.2 4.2e-32 111.8 4.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK62186.1 - 8.4e-15 54.7 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK62186.1 - 1.1e-12 48.0 0.4 8.9e-11 41.7 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAK62186.1 - 2.2e-05 24.1 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 GAK62186.1 - 0.0024 16.5 0.0 0.0033 16.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.7 GAK62186.1 - 0.018 14.7 0.0 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.13 GAK62186.1 - 0.019 14.2 0.0 0.52 9.5 0.0 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family WD40 PF00400.27 GAK62187.1 - 0.0031 17.3 0.0 1.2 9.1 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Chitin_synth_1 PF01644.12 GAK62188.1 - 8.3e-88 292.3 0.1 1.4e-87 291.6 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAK62188.1 - 8.6e-32 108.6 0.2 1.8e-31 107.6 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAK62188.1 - 2.1e-20 72.6 2.0 3e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 GAK62188.1 - 2.5e-06 27.4 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAK62188.1 - 0.00043 20.0 13.6 0.0056 16.4 9.4 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Zn_clus PF00172.13 GAK62189.1 - 1.1e-09 38.0 8.1 2.2e-09 37.0 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MutS_V PF00488.16 GAK62190.1 - 1.6e-43 148.8 0.0 1.1e-39 136.3 0.0 2.3 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 GAK62190.1 - 2.6e-14 53.4 1.0 4.4e-14 52.7 0.7 1.3 1 0 0 1 1 1 1 MutS domain III NB-ARC PF00931.17 GAK62190.1 - 0.0017 17.2 0.0 0.0051 15.7 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAK62190.1 - 0.011 15.8 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MutS_IV PF05190.13 GAK62190.1 - 0.021 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV AAA_14 PF13173.1 GAK62190.1 - 0.035 13.9 0.0 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAK62190.1 - 0.042 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 GAK62190.1 - 0.19 10.6 0.0 0.38 9.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Pkinase PF00069.20 GAK62191.1 - 1e-62 211.6 0.0 1.5e-62 211.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62191.1 - 6.7e-40 136.8 0.0 8.7e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK62191.1 - 5.9e-08 32.0 0.0 8e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 GAK62191.1 - 0.085 12.1 0.1 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DUF814 PF05670.8 GAK62192.1 - 1.4e-20 72.9 0.0 2.6e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF3027 PF11228.3 GAK62192.1 - 0.074 12.7 0.2 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DUF956 PF06115.6 GAK62192.1 - 0.074 12.6 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF956) CAF-1_p150 PF11600.3 GAK62192.1 - 0.63 9.3 23.3 0.89 8.8 16.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Atg14 PF10186.4 GAK62192.1 - 0.72 8.7 9.4 0.85 8.5 6.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 GAK62192.1 - 6.8 6.2 8.2 9.3 5.7 5.7 1.2 1 0 0 1 1 1 0 IncA protein Histone PF00125.19 GAK62193.1 - 3.1e-20 72.0 0.0 5.8e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAK62193.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Formyl_trans_N PF00551.14 GAK62194.1 - 7.6e-29 100.5 0.0 4.6e-18 65.3 0.1 2.8 2 1 0 2 2 2 2 Formyl transferase Gelsolin PF00626.17 GAK62194.1 - 0.012 15.2 0.1 0.061 13.0 0.0 2.3 3 0 0 3 3 3 0 Gelsolin repeat His_binding PF02098.11 GAK62194.1 - 0.24 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Tick histamine binding protein Zn_clus PF00172.13 GAK62195.1 - 8e-08 32.0 6.0 1.3e-07 31.3 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma70_ECF PF07638.6 GAK62197.1 - 0.16 11.6 0.4 0.3 10.7 0.3 1.3 1 0 0 1 1 1 0 ECF sigma factor Oxidored_q2 PF00420.19 GAK62197.1 - 4.8 6.8 11.7 86 2.8 8.1 2.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Arrestin_N PF00339.24 GAK62198.1 - 8.1e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain zf-CCHC PF00098.18 GAK62199.1 - 0.0031 17.3 2.6 0.0031 17.3 1.8 5.1 5 0 0 5 5 5 1 Zinc knuckle zf-CCHC_4 PF14392.1 GAK62199.1 - 0.85 9.3 29.1 0.21 11.2 1.7 4.3 4 1 1 5 5 5 0 Zinc knuckle zf-ribbon_3 PF13248.1 GAK62199.1 - 2.5 7.4 8.9 3.4 7.0 0.4 3.7 3 0 0 3 3 3 0 zinc-ribbon domain MSP1_C PF07462.6 GAK62199.1 - 3.6 5.8 6.9 6.5 5.0 4.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Chitin_synth_1 PF01644.12 GAK62200.1 - 1.6e-87 291.4 0.0 2.3e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAK62200.1 - 4.7e-33 112.7 0.2 1e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAK62200.1 - 1.4e-26 93.0 6.7 5.5e-21 74.5 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 GAK62200.1 - 2.1e-07 30.8 2.1 2.1e-07 30.8 1.4 2.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK62200.1 - 7.7e-06 25.8 0.0 1.9e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PDT PF00800.13 GAK62201.1 - 1e-63 214.1 0.0 3.1e-63 212.6 0.0 1.9 2 0 0 2 2 2 1 Prephenate dehydratase Pil1 PF13805.1 GAK62201.1 - 2.8e-23 82.4 0.6 6e-23 81.3 0.4 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 V_ATPase_I PF01496.14 GAK62201.1 - 1.2 6.9 0.9 1.8 6.3 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNase_PH PF01138.16 GAK62202.1 - 2.9e-24 85.8 0.0 5.6e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAK62202.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cnd3 PF12719.2 GAK62203.1 - 1.7e-83 280.0 4.2 1.3e-82 277.1 0.5 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 GAK62203.1 - 1e-12 48.1 10.7 5.5e-08 32.9 0.4 4.6 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.17 GAK62203.1 - 2.5e-09 36.4 9.8 0.46 10.6 0.1 6.3 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.1 GAK62203.1 - 6.5e-06 26.4 10.4 0.14 12.6 0.0 6.0 4 1 1 5 5 5 2 HEAT-like repeat MMS19_N PF14500.1 GAK62203.1 - 0.00027 20.3 1.0 0.0048 16.2 0.1 2.8 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.2 GAK62203.1 - 0.056 13.2 2.9 7.1 6.4 0.1 3.8 2 2 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 GAK62203.1 - 0.17 11.7 1.5 22 5.0 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Nucleoplasmin PF03066.10 GAK62203.1 - 0.66 9.4 19.7 2.6 7.5 4.8 4.2 4 0 0 4 4 4 0 Nucleoplasmin Sporozoite_P67 PF05642.6 GAK62203.1 - 8.2 4.1 6.6 9.5 3.9 0.0 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NAD_binding_7 PF13241.1 GAK62204.1 - 5.2e-29 100.5 0.0 8.6e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 GAK62204.1 - 1.7e-21 75.2 0.2 2.7e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 GAK62204.1 - 3.3e-09 35.5 0.2 6.9e-09 34.5 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 GAK62204.1 - 0.17 11.6 0.1 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 ThiF family TPR_11 PF13414.1 GAK62205.1 - 4.1e-29 100.0 26.3 1.1e-10 40.9 0.5 11.4 9 3 6 15 15 14 9 TPR repeat TPR_1 PF00515.23 GAK62205.1 - 8.9e-24 82.0 9.0 0.003 17.1 0.1 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAK62205.1 - 5.3e-21 72.7 27.2 0.0048 16.7 0.2 13.4 16 0 0 16 16 13 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAK62205.1 - 1.4e-20 71.6 14.6 0.00054 19.9 0.0 12.5 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAK62205.1 - 3.8e-19 66.9 4.0 0.061 13.1 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAK62205.1 - 4.5e-19 68.1 36.2 1.6e-06 27.9 0.0 11.3 8 3 2 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAK62205.1 - 9.2e-19 67.6 81.0 0.00014 22.4 0.2 16.7 13 4 6 20 20 18 7 Tetratricopeptide repeat TPR_7 PF13176.1 GAK62205.1 - 1.2e-11 43.4 12.6 0.13 12.0 0.0 8.9 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAK62205.1 - 3.1e-11 43.4 45.6 0.00063 20.0 0.0 10.5 9 2 3 12 12 11 5 Tetratricopeptide repeat Apc3 PF12895.2 GAK62205.1 - 2e-09 37.4 9.0 0.0002 21.4 0.0 7.0 7 1 1 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAK62205.1 - 3.3e-09 36.5 78.8 0.0013 19.1 0.2 17.9 14 4 6 20 20 17 5 Tetratricopeptide repeat TPR_6 PF13174.1 GAK62205.1 - 5.1e-08 32.8 18.0 0.15 12.5 0.0 12.0 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAK62205.1 - 0.0026 17.5 27.6 0.38 10.6 0.6 8.5 7 2 3 10 10 9 2 Tetratricopeptide repeat NARP1 PF12569.3 GAK62205.1 - 0.0085 14.8 5.9 0.54 8.9 0.0 4.5 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 ChAPs PF09295.5 GAK62205.1 - 0.018 13.8 0.1 0.079 11.7 0.0 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TOM20_plant PF06552.7 GAK62205.1 - 0.019 14.5 0.6 3 7.3 0.0 3.7 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Fungal_trans_2 PF11951.3 GAK62207.1 - 4.6e-11 41.9 4.1 3.2e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK62207.1 - 0.00053 19.8 10.2 0.00094 19.0 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 GAK62208.1 - 2.3e-40 136.1 9.8 7.7e-17 60.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CTK3 PF12243.3 GAK62209.1 - 7.1e-41 139.0 0.1 1.1e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 GAK62209.1 - 5.3e-13 48.7 8.5 1.1e-10 41.4 5.9 2.4 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus PI3Ka PF00613.15 GAK62210.1 - 2.1e-52 176.9 0.0 4e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAK62210.1 - 6.6e-43 146.8 0.0 3.3e-42 144.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAK62210.1 - 8.4e-38 129.3 0.0 3e-37 127.5 0.0 2.0 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 Chromo PF00385.19 GAK62210.1 - 1.4e-06 27.9 0.1 3.6e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PigN PF04987.9 GAK62211.1 - 4e-91 305.8 16.4 2.5e-89 299.9 9.8 2.1 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 GAK62211.1 - 8.9e-06 25.2 0.5 0.0023 17.3 0.1 2.6 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAK62211.1 - 0.0032 16.6 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase UQ_con PF00179.21 GAK62212.1 - 2.8e-16 59.1 0.0 3.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC_tran PF00005.22 GAK62213.1 - 9.2e-50 168.5 0.0 4.9e-27 94.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAK62213.1 - 9.7e-43 146.5 23.5 1.1e-24 87.3 5.2 3.7 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAK62213.1 - 7.4e-12 45.8 0.0 0.032 14.1 0.0 4.3 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAK62213.1 - 1.4e-11 44.0 0.3 0.032 13.4 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAK62213.1 - 4.3e-09 35.7 0.3 0.00028 20.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAK62213.1 - 2.5e-07 30.3 0.1 0.0047 16.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 GAK62213.1 - 5.9e-07 30.0 3.1 0.00015 22.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 GAK62213.1 - 1.7e-06 28.2 0.3 0.064 13.4 0.1 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK62213.1 - 2.8e-06 27.4 0.1 0.045 13.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAK62213.1 - 3.9e-05 23.8 0.2 0.54 10.4 0.1 3.9 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 GAK62213.1 - 4.6e-05 24.2 0.1 0.52 11.1 0.0 3.4 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 GAK62213.1 - 0.00015 20.7 0.0 0.074 11.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 GAK62213.1 - 0.00065 19.2 0.1 0.24 10.7 0.1 2.6 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 GAK62213.1 - 0.00097 18.2 0.2 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 GAK62213.1 - 0.0013 17.9 0.0 0.059 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAK62213.1 - 0.0017 18.2 0.3 2.1 8.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 GAK62213.1 - 0.0021 17.5 1.2 0.072 12.5 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family Miro PF08477.8 GAK62213.1 - 0.0022 18.4 0.5 0.4 11.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 GAK62213.1 - 0.0087 15.8 3.0 0.066 13.0 0.0 3.2 4 0 0 4 4 3 1 Dynamin family AAA_18 PF13238.1 GAK62213.1 - 0.01 16.1 0.7 6.1 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAK62213.1 - 0.02 14.5 0.2 6.6 6.4 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAK62213.1 - 0.041 13.7 3.9 1.3 8.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 GAK62213.1 - 0.047 13.3 0.1 0.64 9.6 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase NB-ARC PF00931.17 GAK62213.1 - 0.088 11.6 0.1 2.8 6.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.7 GAK62213.1 - 0.13 11.9 1.9 5.7 6.5 0.0 2.9 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.17 GAK62213.1 - 0.18 12.0 0.1 11 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 GAK62213.1 - 0.19 11.6 0.0 26 4.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.10 GAK62213.1 - 0.2 10.2 0.0 0.43 9.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF87 PF01935.12 GAK62213.1 - 0.28 10.9 6.2 2.5 7.8 0.1 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 Gtr1_RagA PF04670.7 GAK62213.1 - 0.66 9.0 3.2 20 4.2 0.0 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Cnd1_N PF12922.2 GAK62213.1 - 6.7 6.3 8.3 10 5.7 1.5 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term FYDLN_acid PF09538.5 GAK62214.1 - 0.016 15.7 6.2 0.016 15.7 4.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) PPP4R2 PF09184.6 GAK62215.1 - 8.6e-14 51.7 3.3 2.8e-13 50.0 0.0 2.5 2 1 0 2 2 2 1 PPP4R2 Glyco_hydro_3 PF00933.16 GAK62216.1 - 5.1e-86 288.3 0.0 7.6e-86 287.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAK62216.1 - 7.1e-61 205.6 1.2 6.3e-60 202.5 0.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAK62216.1 - 3.7e-14 52.4 0.0 7.4e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Cutinase PF01083.17 GAK62217.1 - 1.3e-36 125.9 2.6 1.5e-36 125.7 1.8 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAK62217.1 - 6.2e-05 22.5 0.1 8.9e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF3485 PF11984.3 GAK62218.1 - 0.028 13.5 0.1 0.031 13.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) PHD PF00628.24 GAK62220.1 - 4.1e-11 42.4 8.0 9.2e-11 41.2 5.5 1.6 1 0 0 1 1 1 1 PHD-finger PEX11 PF05648.9 GAK62223.1 - 4.1e-17 62.2 0.0 1.7e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HCNGP PF07818.8 GAK62224.1 - 9.1e-16 57.6 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein Ribosomal_L35p PF01632.14 GAK62225.1 - 0.0024 17.7 5.2 0.0028 17.5 1.5 2.4 2 1 0 2 2 2 1 Ribosomal protein L35 SPA PF08616.5 GAK62227.1 - 3.7e-06 26.6 0.0 6.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.16 GAK62227.1 - 0.0019 17.9 0.0 0.081 12.6 0.0 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.4 GAK62227.1 - 0.0077 14.7 0.0 1.8 6.9 0.0 2.3 2 0 0 2 2 2 2 Transport protein Avl9 Ribosomal_S9 PF00380.14 GAK62228.1 - 6.3e-40 136.2 0.0 1.3e-39 135.1 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L4 PF00573.17 GAK62229.1 - 1e-69 233.7 0.0 1.5e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family SNF2_N PF00176.18 GAK62231.1 - 9.3e-55 185.5 0.0 1.4e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 GAK62231.1 - 1.7e-07 30.8 7.5 3.6e-07 29.7 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK62231.1 - 3.7e-07 29.8 9.3 3.7e-07 29.8 6.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAK62231.1 - 1.1e-06 28.1 7.8 1.2e-06 28.0 4.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK62231.1 - 4.5e-06 26.5 9.7 4.5e-06 26.5 6.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAK62231.1 - 7.7e-05 22.3 3.2 0.00019 21.0 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 GAK62231.1 - 8.9e-05 22.1 6.1 0.00023 20.7 4.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 GAK62231.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 GAK62231.1 - 0.2 11.5 7.8 0.52 10.2 5.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 GAK62231.1 - 1.8 8.2 10.6 0.31 10.6 4.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NUFIP1 PF10453.4 GAK62232.1 - 1.8e-15 56.1 1.7 1.8e-15 56.1 1.2 1.9 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 GAK62232.1 - 5.2e-05 22.8 1.9 0.0001 21.8 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cwf_Cwc_15 PF04889.7 GAK62232.1 - 3.3 7.3 22.9 0.67 9.6 6.8 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Abhydrolase_1 PF00561.15 GAK62233.1 - 1e-25 90.6 0.2 2.8e-25 89.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK62233.1 - 1.2e-25 90.7 1.0 2.1e-25 89.9 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK62233.1 - 3.2e-11 43.1 0.1 2.5e-10 40.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAK62233.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 GAK62233.1 - 0.15 10.5 0.0 0.22 9.9 0.0 1.3 1 0 0 1 1 1 0 Ndr family GCV_T PF01571.16 GAK62235.1 - 6e-67 225.0 0.3 1.4e-66 223.8 0.0 1.7 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAK62235.1 - 4.8e-26 90.6 0.1 1.2e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Glyco_transf_20 PF00982.16 GAK62236.1 - 2e-186 620.1 0.0 2.6e-138 461.4 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 GAK62236.1 - 0.0089 15.4 0.1 3.6 6.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Lactamase_B PF00753.22 GAK62237.1 - 2.8e-17 63.0 3.3 3.6e-17 62.6 2.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAK62237.1 - 0.033 13.7 0.5 0.046 13.2 0.3 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Fib_alpha PF08702.5 GAK62238.1 - 0.4 10.7 6.0 0.85 9.7 4.2 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 GAK62238.1 - 7.2 4.3 5.7 10 3.8 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L36e PF01158.13 GAK62240.1 - 2.4e-37 126.8 4.6 3.3e-37 126.3 3.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e Calcipressin PF04847.7 GAK62241.1 - 9.9e-30 103.4 0.0 1.7e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Calcipressin Voldacs PF03517.8 GAK62241.1 - 5.4e-29 100.7 0.5 2.1e-27 95.6 0.0 3.0 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling RRM_1 PF00076.17 GAK62241.1 - 0.18 11.4 0.0 0.47 10.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GMC_oxred_N PF00732.14 GAK62242.1 - 3.7e-50 170.7 0.0 5.8e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK62242.1 - 3.1e-34 118.3 0.0 5.2e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAK62242.1 - 4.4e-06 25.8 0.3 0.00042 19.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK62242.1 - 0.00011 21.1 0.4 0.039 12.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAK62242.1 - 0.00043 20.2 0.3 0.0022 17.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAK62242.1 - 0.0012 17.8 0.3 0.0019 17.1 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAK62242.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK62242.1 - 0.08 12.7 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 GAK62242.1 - 0.13 11.3 0.1 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 GAK62242.1 - 0.21 10.1 0.1 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase F-actin_cap_A PF01267.12 GAK62243.1 - 1.2e-85 286.9 0.0 1.5e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Stimulus_sens_1 PF13756.1 GAK62243.1 - 0.01 16.2 4.2 0.014 15.7 0.9 2.3 2 0 0 2 2 2 0 Stimulus-sensing domain NMT1 PF09084.6 GAK62244.1 - 0.0053 16.3 0.1 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 GAK62244.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family Pkinase PF00069.20 GAK62245.1 - 2.2e-71 240.0 0.0 2.7e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62245.1 - 2.4e-29 102.2 0.0 3.4e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK62245.1 - 0.012 15.3 0.1 0.03 14.0 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family OB_NTP_bind PF07717.11 GAK62246.1 - 1.4e-13 50.6 0.0 3e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAK62246.1 - 3.3e-12 46.3 0.0 8.4e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAK62246.1 - 1.4e-08 34.4 0.0 3.5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK62246.1 - 2.7e-06 26.9 1.3 5.2e-05 22.8 0.9 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAK62246.1 - 0.0011 19.1 0.1 0.006 16.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 GAK62246.1 - 0.0073 15.2 0.0 0.018 13.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 GAK62246.1 - 0.017 14.6 0.1 0.045 13.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 GAK62246.1 - 0.029 14.2 0.1 1.9 8.3 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.11 GAK62246.1 - 0.037 13.2 0.1 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 GAK62246.1 - 0.037 13.5 0.9 0.76 9.3 0.0 2.5 2 1 0 3 3 3 0 AAA domain AAA_19 PF13245.1 GAK62246.1 - 0.059 13.1 3.5 0.15 11.8 0.2 3.3 3 0 0 3 3 3 0 Part of AAA domain AAA_10 PF12846.2 GAK62246.1 - 0.066 12.6 0.7 0.62 9.4 0.5 2.6 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 GAK62246.1 - 0.07 13.4 0.3 0.34 11.2 0.2 2.1 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 GAK62246.1 - 0.27 10.7 1.2 0.98 8.9 0.5 2.0 1 1 1 2 2 2 0 P-loop containing region of AAA domain DUF605 PF04652.11 GAK62246.1 - 4.1 6.6 11.1 6.5 6.0 4.4 2.2 2 0 0 2 2 2 0 Vta1 like ADH_N PF08240.7 GAK62247.1 - 1.1e-27 95.9 0.9 1.8e-27 95.2 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK62247.1 - 4.6e-10 39.1 0.0 8.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK62247.1 - 0.002 18.9 0.0 0.004 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GST_C_3 PF14497.1 GAK62248.1 - 1.6e-08 34.9 0.0 2.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAK62248.1 - 0.0029 17.5 0.1 0.008 16.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HECT PF00632.20 GAK62249.1 - 1.6e-90 303.5 0.0 2.4e-90 302.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Methyltransf_28 PF02636.12 GAK62250.1 - 8.4e-36 123.6 0.0 1.5e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 GAK62250.1 - 2.2e-05 23.6 0.0 4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAK62250.1 - 0.0011 19.0 0.4 0.0034 17.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK62250.1 - 0.0035 17.8 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAK62250.1 - 0.011 15.4 0.3 0.065 12.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PRMT5 PF05185.11 GAK62250.1 - 0.035 13.0 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 GAK62250.1 - 0.13 12.8 0.8 0.33 11.5 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain HD_3 PF13023.1 GAK62251.1 - 4.7e-39 133.7 0.2 4.7e-39 133.7 0.1 2.3 2 0 0 2 2 2 1 HD domain DUF1752 PF08550.5 GAK62251.1 - 5.5e-12 45.0 2.0 1.2e-11 43.9 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RAB3GAP2_N PF14655.1 GAK62251.1 - 1.7 7.5 7.0 3 6.7 4.8 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TSA PF03249.8 GAK62251.1 - 7.8 4.9 13.9 18 3.7 9.6 1.5 1 0 0 1 1 1 0 Type specific antigen Peptidase_C48 PF02902.14 GAK62252.1 - 8.6e-28 97.4 0.0 6.6e-19 68.3 0.0 3.1 3 1 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain FTO_CTD PF12934.2 GAK62252.1 - 0.037 13.5 1.6 0.61 9.6 0.7 2.5 2 0 0 2 2 2 0 FTO C-terminal domain ADH_N PF08240.7 GAK62253.1 - 7e-28 96.5 0.2 2e-27 95.1 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK62253.1 - 5.7e-21 74.4 2.7 1.6e-19 69.7 1.9 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK62253.1 - 0.001 19.9 0.0 0.027 15.3 0.0 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fer2_BFD PF04324.10 GAK62253.1 - 0.045 13.7 0.7 5.8 7.0 0.3 2.4 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain PrmA PF06325.8 GAK62253.1 - 0.056 12.5 0.7 0.087 11.9 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AlaDh_PNT_C PF01262.16 GAK62253.1 - 0.16 11.5 0.7 0.31 10.5 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M43 PF05572.8 GAK62254.1 - 3.6e-17 62.3 0.0 6.8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 GAK62254.1 - 0.00021 21.2 1.0 0.00037 20.4 0.0 1.8 1 1 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 GAK62254.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 GAK62254.1 - 0.0025 18.3 0.5 0.0025 18.3 0.3 3.0 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 GAK62254.1 - 0.0092 16.0 2.5 0.074 13.0 1.7 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 GAK62254.1 - 0.028 13.9 0.4 0.075 12.5 0.0 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 GAK62254.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF1115 PF06544.7 GAK62255.1 - 9e-15 54.4 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) TMCO5 PF14992.1 GAK62256.1 - 0.71 8.9 9.1 1.2 8.2 6.3 1.2 1 0 0 1 1 1 0 TMCO5 family Ribosomal_L13 PF00572.13 GAK62257.1 - 5.3e-48 162.3 0.6 8.8e-48 161.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Iso_dh PF00180.15 GAK62258.1 - 5.5e-86 288.6 0.0 6.4e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MAPEG PF01124.13 GAK62259.1 - 1.5e-14 53.6 4.7 1.9e-14 53.3 3.2 1.1 1 0 0 1 1 1 1 MAPEG family HTH_Tnp_Tc5 PF03221.11 GAK62260.1 - 2.3e-13 49.7 0.0 4.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 GAK62260.1 - 0.00038 19.8 0.0 0.001 18.4 0.0 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_4 PF13613.1 GAK62260.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Ribosomal_L7Ae PF01248.21 GAK62261.1 - 9e-21 73.2 0.6 1.6e-20 72.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ldh_1_N PF00056.18 GAK62262.1 - 7.8e-45 152.1 0.1 1.1e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAK62262.1 - 7.1e-44 149.5 0.0 1e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 GAK62262.1 - 6.7e-05 21.7 0.0 0.00019 20.2 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 GAK62262.1 - 0.0032 16.5 0.5 0.11 11.5 0.0 2.6 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 GAK62262.1 - 0.031 14.5 0.2 0.099 12.9 0.0 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 GAK62262.1 - 0.084 12.1 0.2 0.39 10.0 0.1 1.9 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Zn_clus PF00172.13 GAK62263.1 - 9.9e-07 28.5 10.3 1.7e-06 27.8 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK62263.1 - 4.4e-05 22.4 0.0 0.00034 19.5 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.23 GAK62265.1 - 2.1e-20 73.6 4.3 3.5e-20 72.9 0.1 3.5 3 1 0 3 3 3 1 SET domain PHD PF00628.24 GAK62266.1 - 2.9e-06 26.8 18.8 4.8e-06 26.1 13.0 1.4 1 0 0 1 1 1 1 PHD-finger Aldolase_II PF00596.16 GAK62268.1 - 3.2e-42 144.2 0.0 4e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CDC37_N PF03234.9 GAK62269.1 - 0.034 14.4 1.0 0.044 14.0 0.7 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding ISG65-75 PF11727.3 GAK62269.1 - 0.098 11.6 1.0 0.12 11.3 0.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein HEXIM PF15313.1 GAK62269.1 - 0.1 12.7 0.6 2.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein DUF972 PF06156.8 GAK62269.1 - 0.15 12.4 0.8 0.2 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Ferritin_2 PF13668.1 GAK62271.1 - 3e-18 66.0 0.1 4.4e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain DSHCT PF08148.7 GAK62273.1 - 6.1e-57 191.7 0.3 1.5e-56 190.4 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAK62273.1 - 1.7e-22 79.6 0.0 3.4e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 GAK62273.1 - 3.7e-06 26.2 1.6 6.5e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.26 GAK62273.1 - 4.1e-06 26.5 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK62273.1 - 0.0023 17.8 0.1 0.041 13.7 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF952 PF06108.7 GAK62274.1 - 7.9e-17 60.9 0.0 1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Mit_KHE1 PF10173.4 GAK62275.1 - 3.9e-53 180.0 0.2 3.9e-53 180.0 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DND1_DSRM PF14709.1 GAK62275.1 - 2.2 8.6 5.7 21 5.4 0.0 3.6 4 0 0 4 4 4 0 double strand RNA binding domain from DEAD END PROTEIN 1 Nbl1_Borealin_N PF10444.4 GAK62276.1 - 4e-16 58.1 1.2 8.1e-16 57.1 0.8 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Slu7 PF11708.3 GAK62276.1 - 8.2 6.0 19.6 6.1 6.5 4.3 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Dfp1_Him1_M PF08630.5 GAK62277.1 - 1e-30 106.0 0.0 1.8e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 GAK62277.1 - 1.7e-21 75.6 0.7 3.1e-21 74.7 0.5 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 GAK62277.1 - 0.011 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF3541 PF12060.3 GAK62277.1 - 0.29 10.4 0.1 0.52 9.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Arf PF00025.16 GAK62278.1 - 2.3e-79 264.6 0.1 2.7e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAK62278.1 - 2.8e-14 52.7 0.0 3.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAK62278.1 - 5.4e-13 48.6 0.0 5.8e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAK62278.1 - 3.3e-12 45.8 1.3 4.3e-09 35.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAK62278.1 - 3.7e-11 42.5 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAK62278.1 - 3e-09 37.3 0.0 4.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAK62278.1 - 6e-06 26.1 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK62278.1 - 0.0044 16.4 0.1 0.028 13.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 GAK62278.1 - 0.0068 15.4 0.3 0.019 14.0 0.1 1.6 1 1 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 GAK62278.1 - 0.075 12.9 0.1 0.14 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 GAK62278.1 - 0.13 11.7 0.2 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_CH_N PF12471.3 GAK62279.1 - 5.2e-88 293.7 0.0 8.4e-88 293.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 GAK62279.1 - 8.7e-13 47.8 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ecl1 PF12855.2 GAK62283.1 - 0.0073 15.5 0.4 0.015 14.6 0.3 1.4 1 0 0 1 1 1 1 Life-span regulatory factor WSC PF01822.14 GAK62283.1 - 0.038 13.9 3.6 0.08 12.8 2.5 1.5 1 0 0 1 1 1 0 WSC domain RPAP2_Rtr1 PF04181.8 GAK62283.1 - 4.5 7.4 6.3 9.9 6.3 4.4 1.7 1 1 0 1 1 1 0 Rtr1/RPAP2 family Thg1C PF14413.1 GAK62284.1 - 2.5e-45 153.0 0.0 5.4e-45 151.9 0.0 1.5 1 1 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 GAK62284.1 - 1.4e-43 147.7 0.0 2.1e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Ferric_reduct PF01794.14 GAK62285.1 - 3.1e-19 69.2 14.9 3.1e-19 69.2 10.3 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAK62285.1 - 1.7e-13 50.3 0.0 3.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAK62285.1 - 2e-11 44.0 0.0 2.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_10 PF13460.1 GAK62286.1 - 4.1e-20 72.5 0.0 6.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAK62286.1 - 9.9e-14 51.1 0.0 1.3e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAK62286.1 - 1.1e-10 41.3 0.1 1.6e-09 37.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK62286.1 - 3.5e-10 39.0 0.0 1.3e-09 37.2 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAK62286.1 - 5.1e-10 38.7 0.0 1.4e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAK62286.1 - 3.8e-08 32.5 0.2 0.0012 17.8 0.1 3.1 1 1 1 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 GAK62286.1 - 0.00015 20.8 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 GAK62286.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 GAK62286.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 GAK62286.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HhH-GPD PF00730.20 GAK62287.1 - 2.6e-12 46.9 0.0 4.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein eIF3_N PF09440.5 GAK62288.1 - 6.9e-46 155.7 0.3 1.3e-45 154.7 0.2 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 GAK62288.1 - 1.8e-10 41.0 0.1 7.6e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 PCI domain MFS_1 PF07690.11 GAK62289.1 - 1.1e-11 44.0 11.2 1.1e-11 44.0 7.8 2.9 2 2 0 2 2 2 1 Major Facilitator Superfamily LtrA PF06772.6 GAK62290.1 - 4.1e-23 81.8 12.9 5.5e-23 81.4 8.9 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Zn_clus PF00172.13 GAK62291.1 - 2.1e-06 27.5 13.6 4.6e-06 26.4 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK62291.1 - 7.7e-05 21.6 0.4 0.00024 20.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain UCH PF00443.24 GAK62292.1 - 5e-57 193.0 0.0 6.8e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK62292.1 - 2e-29 102.9 0.4 2.2e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Raffinose_syn PF05691.7 GAK62292.1 - 1.4e-19 69.2 0.1 2.2e-18 65.2 0.1 2.3 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 MFS_1 PF07690.11 GAK62293.1 - 9.4e-32 110.0 20.3 9.4e-32 110.0 14.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily EXS PF03124.9 GAK62293.1 - 0.0017 17.4 1.4 0.0098 14.9 1.0 2.2 1 1 0 1 1 1 1 EXS family Vpu PF00558.14 GAK62293.1 - 0.15 11.6 0.6 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 Vpu protein Wzy_C PF04932.10 GAK62293.1 - 2.2 8.0 11.1 0.11 12.2 0.4 2.9 2 1 1 3 3 3 0 O-Antigen ligase DASH_Dad4 PF08650.5 GAK62294.1 - 5.4e-18 64.6 2.8 5.9e-18 64.5 1.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 UBN2_2 PF14227.1 GAK62294.1 - 0.018 14.5 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type GTPase_Cys_C PF12631.2 GAK62294.1 - 0.05 14.0 0.8 0.11 12.9 0.6 1.7 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Ins134_P3_kin PF05770.6 GAK62294.1 - 0.058 12.3 0.1 0.064 12.2 0.1 1.0 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase DASH_Dad1 PF08649.5 GAK62294.1 - 0.11 12.1 0.6 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 Hydrolase PF00702.21 GAK62295.1 - 3.1e-22 80.0 0.0 3.2e-21 76.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAK62295.1 - 7.8e-22 77.4 0.1 2.1e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 GAK62295.1 - 7.9e-19 68.5 0.0 1.5e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK62295.1 - 0.00026 20.8 0.0 0.00056 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAK62295.1 - 0.02 14.4 0.0 0.065 12.7 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK62295.1 - 0.047 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Bac_rhodopsin PF01036.13 GAK62296.1 - 2.5e-44 151.2 16.4 3.1e-44 150.9 11.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein ResIII PF04851.10 GAK62296.1 - 0.061 13.1 0.2 0.084 12.6 0.2 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arteri_Gl PF00951.13 GAK62296.1 - 1.1 8.8 7.4 0.072 12.6 0.4 2.0 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein UQ_con PF00179.21 GAK62297.1 - 6.3e-41 139.0 0.0 7.9e-41 138.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAK62297.1 - 0.00025 20.9 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 GAK62297.1 - 0.032 13.6 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 GAK62297.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B PLDc PF00614.17 GAK62298.1 - 1.2e-14 53.5 0.2 2e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 GAK62298.1 - 7.6e-12 45.0 0.0 1.6e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 GAK62298.1 - 2.3e-10 40.2 0.0 6.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 PX domain Rrp15p PF07890.7 GAK62299.1 - 2.6e-33 114.8 5.7 2.6e-33 114.8 3.9 2.2 1 1 1 2 2 2 1 Rrp15p YL1 PF05764.8 GAK62299.1 - 1.8 8.0 22.0 0.13 11.8 10.6 2.1 2 1 0 2 2 2 0 YL1 nuclear protein PBP1_TM PF14812.1 GAK62299.1 - 4 7.8 18.2 0.29 11.4 5.0 3.2 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LZ_Tnp_IS66 PF13007.2 GAK62299.1 - 4.4 8.0 26.7 0.42 11.3 3.0 4.0 3 1 0 3 3 3 0 Transposase C of IS166 homeodomain Adeno_PIX PF03955.9 GAK62299.1 - 5.6 7.5 8.5 0.2 12.1 0.7 2.3 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) ATP-grasp_2 PF08442.5 GAK62300.1 - 5e-73 244.7 0.7 7.4e-73 244.2 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 GAK62300.1 - 4.3e-22 78.3 1.1 1e-21 77.1 0.5 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 GAK62300.1 - 3.8e-13 49.1 0.6 6.7e-13 48.3 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 GAK62300.1 - 0.00013 21.6 0.9 0.00028 20.5 0.1 2.0 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 GAK62300.1 - 0.00026 20.7 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 GAK62300.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain PepSY PF03413.14 GAK62300.1 - 0.014 16.0 0.8 1.5 9.5 0.1 3.4 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain PASTA PF03793.14 GAK62300.1 - 0.18 11.4 0.4 0.81 9.3 0.1 2.3 2 0 0 2 2 2 0 PASTA domain Ceramidase_alk PF04734.8 GAK62301.1 - 3.2e-218 725.9 0.0 3.6e-216 719.1 0.0 2.8 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase MCM PF00493.18 GAK62302.1 - 2.7e-136 453.7 0.5 4e-136 453.1 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAK62302.1 - 7.5e-20 71.6 0.2 3.8e-19 69.3 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAK62302.1 - 1.6e-07 30.7 0.0 7.8e-07 28.4 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAK62302.1 - 0.0023 17.4 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 GAK62302.1 - 0.0029 17.2 0.0 0.0089 15.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAK62302.1 - 0.032 13.9 0.0 0.13 11.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1876 PF08962.6 GAK62303.1 - 0.011 15.5 0.3 0.02 14.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) DUF1003 PF06210.6 GAK62304.1 - 2.4 8.1 5.2 5.4 6.9 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Prp31_C PF09785.4 GAK62305.1 - 4e-41 140.3 4.4 4e-41 140.3 3.1 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 GAK62305.1 - 1.2e-37 128.5 0.5 2.2e-37 127.6 0.3 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAK62305.1 - 1e-18 66.8 0.0 1.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain CD99L2 PF12301.3 GAK62305.1 - 2.5 7.7 11.6 0.33 10.6 4.7 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 AMP-binding PF00501.23 GAK62306.1 - 2e-86 289.9 0.0 3.5e-86 289.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ADH_zinc_N PF00107.21 GAK62306.1 - 2.2e-18 66.0 2.8 3.3e-18 65.4 0.5 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AMP-binding_C PF13193.1 GAK62306.1 - 8e-17 61.9 0.1 2.4e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N_2 PF13602.1 GAK62306.1 - 2.7e-10 41.2 0.3 2.1e-09 38.3 0.1 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK62306.1 - 0.00042 20.0 1.0 0.0031 17.2 0.0 2.9 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 GAK62306.1 - 0.085 12.8 0.1 0.33 10.9 0.1 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MOSC_N PF03476.11 GAK62307.1 - 3.2e-19 68.7 0.0 6.8e-19 67.7 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAK62307.1 - 1.7e-10 40.5 0.0 3.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Cytochrom_D1 PF02239.11 GAK62307.1 - 0.096 10.9 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain CorA PF01544.13 GAK62308.1 - 3.7e-46 157.4 0.4 5.4e-46 156.9 0.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.1 GAK62308.1 - 0.057 13.7 0.1 0.16 12.3 0.1 1.7 2 0 0 2 2 2 0 ACT domain Baculo_PEP_C PF04513.7 GAK62308.1 - 0.089 12.6 0.9 0.2 11.4 0.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 GAK62308.1 - 0.16 11.6 0.3 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) SUR7 PF06687.7 GAK62310.1 - 4.9e-30 104.6 2.0 8.1e-30 103.9 1.4 1.4 1 0 0 1 1 1 1 SUR7/PalI family MIT PF04212.13 GAK62311.1 - 3.4e-05 23.6 0.1 8.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain MerC PF03203.9 GAK62312.1 - 3.5 8.0 8.9 0.29 11.5 2.0 2.3 2 1 0 2 2 2 0 MerC mercury resistance protein DIL PF01843.14 GAK62313.1 - 3.5e-27 94.3 0.3 7e-27 93.3 0.2 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 GAK62313.1 - 1.6e-15 57.1 0.0 5.2e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAK62313.1 - 2.7e-13 49.0 1.3 7.1e-08 31.8 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAK62313.1 - 8.6e-12 45.2 0.1 6.1e-06 26.5 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK62313.1 - 7.4e-11 41.1 0.0 8.5e-05 22.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAK62313.1 - 2.4e-08 33.9 0.1 0.00088 19.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF2146 PF10220.4 GAK62313.1 - 0.5 8.2 3.4 0.91 7.4 2.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SGT1 PF07093.6 GAK62314.1 - 2.7e-135 452.0 11.4 5.6e-135 451.0 7.9 1.3 1 1 0 1 1 1 1 SGT1 protein PG_binding_2 PF08823.6 GAK62314.1 - 0.0053 16.8 0.1 0.017 15.2 0.1 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DUF479 PF04336.7 GAK62314.1 - 0.099 12.7 0.5 3.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF479 Peptidase_C48 PF02902.14 GAK62315.1 - 5.1e-39 134.1 0.0 1.2e-35 123.1 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Cupin_8 PF13621.1 GAK62316.1 - 5.5e-22 78.4 0.2 8.1e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 GAK62316.1 - 2.1e-15 56.9 0.5 5.9e-15 55.4 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 GAK62316.1 - 0.013 14.9 0.0 0.038 13.4 0.0 1.8 1 0 0 1 1 1 0 Cupin domain GPI PF06560.6 GAK62316.1 - 0.018 14.0 0.1 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) UPF0061 PF02696.9 GAK62317.1 - 3.2e-85 286.2 0.0 4.5e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Mannosyl_trans PF05007.8 GAK62318.1 - 4.9e-59 200.0 21.0 4e-57 193.8 9.5 2.5 3 0 0 3 3 3 2 Mannosyltransferase (PIG-M) p450 PF00067.17 GAK62319.1 - 2.8e-53 181.0 0.0 3.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SLX9 PF15341.1 GAK62320.1 - 1.7e-20 73.6 7.2 2.7e-20 72.9 5.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF4335 PF14233.1 GAK62320.1 - 0.057 12.8 0.3 0.092 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4335) Sigma70_ner PF04546.8 GAK62320.1 - 0.086 12.4 4.7 0.12 11.9 3.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TP_methylase PF00590.15 GAK62320.1 - 0.11 12.2 0.3 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases SAPS PF04499.10 GAK62320.1 - 0.16 10.5 5.1 0.2 10.2 3.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop25 PF09805.4 GAK62320.1 - 0.26 11.3 6.8 0.51 10.4 4.7 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CAF-1_p150 PF11600.3 GAK62320.1 - 0.28 10.5 10.1 0.64 9.3 6.5 1.7 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nucleoplasmin PF03066.10 GAK62320.1 - 3 7.3 8.1 4.1 6.8 4.4 1.9 2 0 0 2 2 2 0 Nucleoplasmin DUF2890 PF11081.3 GAK62320.1 - 4.4 7.3 10.6 0.092 12.7 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Vfa1 PF08432.5 GAK62320.1 - 4.5 7.2 8.9 3.9 7.4 5.5 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Lipase_3 PF01764.20 GAK62321.1 - 1.4e-17 63.5 0.0 5.5e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 GAK62321.1 - 0.01 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.4 GAK62321.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF2974 PF11187.3 GAK62321.1 - 0.16 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TFCD_C PF12612.3 GAK62322.1 - 4.6e-30 104.4 0.0 1.2e-28 99.8 0.0 2.8 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 GAK62322.1 - 0.012 15.8 23.2 0.43 10.8 0.0 7.2 5 1 1 7 7 7 0 HEAT repeats Vac14_Fab1_bd PF12755.2 GAK62322.1 - 0.013 15.8 0.0 6.6 7.1 0.0 4.1 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 GAK62322.1 - 0.021 14.7 0.0 0.2 11.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) HEAT PF02985.17 GAK62322.1 - 0.12 12.5 0.1 0.12 12.5 0.0 8.1 10 0 0 10 10 10 0 HEAT repeat Methyltransf_23 PF13489.1 GAK62323.1 - 2e-17 63.3 0.6 3.6e-17 62.5 0.4 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK62323.1 - 1.8e-14 54.0 0.0 3.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK62323.1 - 4.7e-12 46.4 0.0 9.6e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK62323.1 - 7.7e-12 45.5 0.0 2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK62323.1 - 1e-11 44.6 0.0 1.5e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK62323.1 - 4.4e-07 29.4 0.1 8.3e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAK62323.1 - 5.1e-07 30.0 0.0 9.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK62323.1 - 7.4e-06 25.9 0.4 2.9e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 GAK62323.1 - 2.5e-05 23.2 0.0 0.00024 20.0 0.0 2.0 1 1 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 GAK62323.1 - 4.4e-05 22.7 0.0 7.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 GAK62323.1 - 7.2e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.15 GAK62323.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 GAK62323.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) NPV_P10 PF05531.7 GAK62323.1 - 0.0032 17.6 0.4 0.007 16.5 0.2 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein CmcI PF04989.7 GAK62323.1 - 0.0076 15.5 0.8 0.011 15.0 0.2 1.4 1 1 0 1 1 1 1 Cephalosporin hydroxylase TehB PF03848.9 GAK62323.1 - 0.034 13.3 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Flavin_Reduct PF01613.13 GAK62324.1 - 5.3e-20 71.8 0.1 8e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain AA_permease PF00324.16 GAK62326.1 - 2.7e-131 438.1 43.5 3.5e-131 437.8 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAK62326.1 - 4e-41 140.9 46.1 5.5e-41 140.4 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease ACT_7 PF13840.1 GAK62328.1 - 8.7e-17 60.4 0.0 4.1e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 ACT domain Glyoxalase_4 PF13669.1 GAK62328.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily XAP5 PF04921.9 GAK62329.1 - 5.7e-95 317.4 7.0 5.7e-95 317.4 4.9 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator Glyco_transf_22 PF03901.12 GAK62330.1 - 3.4e-30 105.3 10.1 4.7e-30 104.9 7.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Syntaxin-18_N PF10496.4 GAK62331.1 - 1.3e-15 57.0 0.1 1.3e-14 53.7 0.0 2.6 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 GAK62331.1 - 0.027 14.1 1.7 0.027 14.1 1.2 2.1 2 0 0 2 2 2 0 SNARE domain Latarcin PF10279.4 GAK62331.1 - 0.18 12.0 1.8 5.9 7.1 0.3 2.7 2 0 0 2 2 2 0 Latarcin precursor UQ_con PF00179.21 GAK62332.1 - 3.8e-44 149.5 0.0 5.2e-44 149.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.20 GAK62333.1 - 1.1e-41 142.7 0.0 7.2e-25 87.6 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62333.1 - 2.3e-17 62.9 0.0 3.1e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase CDK2AP PF09806.4 GAK62334.1 - 0.52 10.5 5.1 0.65 10.2 3.4 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Sec1 PF00995.18 GAK62335.1 - 5.3e-150 500.7 0.0 6.1e-150 500.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family 4HBT_3 PF13622.1 GAK62336.1 - 1e-38 133.5 0.6 1.8e-38 132.7 0.4 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 GAK62336.1 - 2.3e-30 104.9 0.0 7.3e-24 83.8 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase Nup88 PF10168.4 GAK62337.1 - 2.3e-16 58.8 0.8 4.4e-11 41.4 0.0 3.6 3 1 0 3 3 3 3 Nuclear pore component TPR_11 PF13414.1 GAK62338.1 - 1.3e-25 88.8 12.3 1.5e-05 24.5 0.0 7.3 6 1 1 7 7 7 6 TPR repeat TPR_2 PF07719.12 GAK62338.1 - 5.8e-18 63.2 12.2 0.055 13.4 0.0 11.1 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAK62338.1 - 1.5e-16 60.5 16.5 3.6e-05 24.3 0.2 7.9 8 2 1 9 9 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAK62338.1 - 1.7e-14 52.4 4.2 0.11 12.3 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAK62338.1 - 2.3e-14 53.0 18.5 0.0024 17.7 0.8 6.8 6 2 1 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAK62338.1 - 4.6e-12 46.0 10.8 3e-05 24.2 0.2 7.5 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAK62338.1 - 1.3e-11 43.5 10.4 0.21 11.2 0.1 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAK62338.1 - 2.8e-10 39.8 14.8 0.00022 21.5 0.8 9.7 8 3 2 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAK62338.1 - 1.2e-09 37.9 4.6 1.2 9.8 0.0 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAK62338.1 - 5.4e-09 35.5 0.1 1.4 9.2 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAK62338.1 - 2.1e-05 23.7 5.8 0.0018 17.4 0.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 GAK62338.1 - 0.00011 22.2 8.1 0.28 11.3 1.6 5.2 4 3 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAK62338.1 - 0.00039 20.2 6.2 0.025 14.4 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAK62338.1 - 0.00051 20.1 5.5 0.9 9.7 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAK62338.1 - 0.00087 18.9 12.9 3.8 7.5 0.0 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 GAK62338.1 - 0.02 15.1 0.6 4 7.6 0.1 2.7 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_4 PF07721.9 GAK62338.1 - 0.086 13.3 7.9 12 6.6 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.3 GAK62338.1 - 0.54 8.9 9.6 0.19 10.4 0.2 3.1 3 1 0 3 3 3 0 NMDA receptor-regulated protein 1 Sld5 PF05916.6 GAK62340.1 - 2.2e-11 43.9 0.0 3.3e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein Glyco_hydro_16 PF00722.16 GAK62341.1 - 1.1e-29 103.0 6.4 2e-29 102.2 4.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 GAK62341.1 - 0.0011 18.8 14.5 0.0026 17.7 10.1 1.6 1 0 0 1 1 1 1 Chitin recognition protein RPAP1_C PF08620.5 GAK62341.1 - 0.16 11.8 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 RPAP1-like, C-terminal Sec10 PF07393.6 GAK62342.1 - 4.2e-280 930.9 0.0 5.2e-280 930.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 CTD_bind PF04818.8 GAK62342.1 - 0.025 14.7 0.7 2.9 8.1 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase II-binding domain. RIX1 PF08167.7 GAK62343.1 - 2e-11 43.8 2.2 4.5e-11 42.7 0.4 2.2 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DnaJ PF00226.26 GAK62344.1 - 1.8e-18 65.9 0.0 3.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain PBP PF01161.15 GAK62345.1 - 6.1e-13 48.8 0.0 8.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RAP1 PF07218.6 GAK62345.1 - 9.6 4.1 11.9 13 3.6 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pex2_Pex12 PF04757.9 GAK62346.1 - 1.1e-39 136.2 4.6 1.8e-39 135.5 3.2 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 GAK62346.1 - 0.0024 17.4 1.7 0.0068 16.0 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK62346.1 - 0.0054 16.5 1.4 0.73 9.7 0.3 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 GAK62346.1 - 0.021 14.8 3.2 0.024 14.6 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK62346.1 - 0.36 10.6 2.4 0.76 9.5 0.4 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Acid_PPase PF12689.2 GAK62347.1 - 9.3e-58 194.5 0.0 1.2e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase DUF903 PF06004.7 GAK62347.1 - 0.003 17.0 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) HAD_2 PF13419.1 GAK62347.1 - 0.09 12.9 0.6 1.6 8.8 0.0 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase MOR2-PAG1_N PF14222.1 GAK62348.1 - 8.5e-159 529.7 0.0 1.9e-158 528.6 0.0 1.6 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 GAK62348.1 - 9.6e-56 189.4 0.5 1.9e-27 96.6 0.0 3.6 4 0 0 4 4 4 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 GAK62348.1 - 2.3e-30 104.9 4.2 4.8e-13 47.6 0.0 4.1 3 1 1 4 4 4 4 Cell morphogenesis central region DUF2454 PF10521.4 GAK62348.1 - 0.036 13.0 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) LCAT PF02450.10 GAK62349.1 - 4.7e-87 292.4 0.2 1.3e-86 291.0 0.1 1.6 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Serglycin PF04360.7 GAK62349.1 - 0.006 16.3 6.4 0.012 15.3 3.9 1.8 2 0 0 2 2 2 1 Serglycin Lipase_2 PF01674.13 GAK62349.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) DWNN PF08783.6 GAK62350.1 - 8.7e-35 118.5 0.0 1.5e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC PF00098.18 GAK62350.1 - 7e-06 25.7 1.6 1.4e-05 24.8 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 GAK62350.1 - 0.0002 21.2 0.1 0.015 15.2 0.0 2.5 1 1 1 2 2 2 1 U-box domain zf-CCHC_3 PF13917.1 GAK62350.1 - 0.00026 20.6 0.3 0.00092 18.8 0.2 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 GAK62350.1 - 0.00098 18.5 3.9 0.0023 17.3 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 GAK62350.1 - 0.006 16.5 13.9 0.006 16.5 9.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 GAK62350.1 - 0.019 14.4 0.6 0.049 13.1 0.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Frigida PF07899.6 GAK62350.1 - 0.23 10.2 1.4 0.37 9.5 1.0 1.2 1 0 0 1 1 1 0 Frigida-like protein Vfa1 PF08432.5 GAK62350.1 - 0.53 10.2 7.9 1.4 8.9 5.5 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-RING_2 PF13639.1 GAK62350.1 - 0.57 10.0 12.4 1.3 8.8 8.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 GAK62350.1 - 4.1 7.2 9.2 0.35 10.6 2.9 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 GAK62350.1 - 6.8 6.4 15.4 13 5.5 10.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.11 GAK62350.1 - 7.5 6.9 6.8 20 5.6 4.7 1.7 1 0 0 1 1 1 0 Trm112p-like protein zf-C3HC4_4 PF15227.1 GAK62350.1 - 9.4 6.2 14.0 25 4.8 9.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CLTH PF10607.4 GAK62351.1 - 2.5e-33 114.7 0.0 3.2e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAK62351.1 - 1.7e-09 37.1 0.0 1.7e-09 37.1 0.0 2.2 3 0 0 3 3 3 1 LisH HEAT_2 PF13646.1 GAK62352.1 - 4.2e-31 107.0 2.6 3.6e-16 59.2 1.1 2.8 2 2 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 GAK62352.1 - 2.3e-19 67.8 1.2 0.00051 20.2 0.0 6.8 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 GAK62352.1 - 2.8e-12 45.5 3.3 0.098 12.7 0.0 6.3 6 1 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 GAK62352.1 - 9.9e-11 41.7 3.3 0.014 15.9 0.0 5.5 4 1 1 6 6 6 4 HEAT-like repeat Arm PF00514.18 GAK62352.1 - 0.00049 19.8 0.9 2.5 8.0 0.0 4.2 4 1 1 5 5 5 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 GAK62352.1 - 0.0061 16.4 2.2 0.043 13.7 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion UPF0147 PF03685.8 GAK62352.1 - 0.014 15.2 0.0 1.4 8.8 0.0 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0147) Ribosomal_L10 PF00466.15 GAK62353.1 - 3.6e-17 62.1 0.0 6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Nucleoplasmin PF03066.10 GAK62353.1 - 0.44 10.0 10.5 0.87 9.0 7.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 GAK62353.1 - 1.3 8.8 5.5 2.7 7.8 3.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 GAK62353.1 - 2.6 7.2 9.3 3.7 6.7 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 GAK62353.1 - 6 6.5 12.1 11 5.6 8.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.8 GAK62353.1 - 9 3.9 16.5 13 3.3 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi F-box-like PF12937.2 GAK62354.1 - 0.019 14.6 1.5 0.091 12.5 0.2 2.5 2 0 0 2 2 2 0 F-box-like Zn_clus PF00172.13 GAK62356.1 - 5.7e-10 38.9 26.5 4.2e-08 32.9 5.8 3.0 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BATS PF06968.8 GAK62357.1 - 8.1e-27 92.9 0.0 2e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 GAK62357.1 - 6.5e-15 55.6 0.1 1.4e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DEAD PF00270.24 GAK62358.1 - 2.8e-47 160.3 0.0 6.3e-46 155.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK62358.1 - 7.2e-21 73.8 0.0 4.5e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAK62358.1 - 6.7e-05 21.8 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAK62358.1 - 0.00022 21.1 0.0 0.00091 19.1 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 GAK62358.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1776 PF08643.5 GAK62359.1 - 1.9e-06 27.2 0.0 0.055 12.5 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.20 GAK62359.1 - 0.0027 17.6 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Asn_synthase PF00733.16 GAK62360.1 - 9.4e-67 225.1 0.2 2e-66 224.1 0.2 1.6 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 GAK62360.1 - 8.9e-38 128.8 0.0 1.4e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAK62360.1 - 4.7e-30 104.2 0.0 1e-29 103.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 GAK62360.1 - 1.7e-08 33.5 0.0 6.4e-05 21.8 0.0 2.8 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 GAK62360.1 - 4e-06 26.1 0.0 8.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 GAK62360.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.11 GAK62360.1 - 0.24 9.9 0.0 0.41 9.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase WD40 PF00400.27 GAK62361.1 - 4.4e-17 61.2 5.9 2.3e-05 24.0 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat AP_endonuc_2 PF01261.19 GAK62363.1 - 9.6e-28 96.9 0.0 1.9e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_trans_4_4 PF13579.1 GAK62364.1 - 5.3 7.1 8.7 0.16 12.0 1.0 1.9 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain PRP21_like_P PF12230.3 GAK62365.1 - 3.1e-61 206.8 1.0 4.8e-60 202.9 0.3 2.5 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 GAK62365.1 - 1.4e-30 104.6 1.1 3.9e-14 52.0 0.2 2.5 2 0 0 2 2 2 2 Surp module Chorismate_bind PF00425.13 GAK62366.1 - 1.1e-84 283.8 0.0 1.5e-84 283.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 GAK62366.1 - 1.2e-28 99.8 0.0 4.3e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region PIG-L PF02585.12 GAK62368.1 - 2e-22 80.0 0.4 3e-22 79.5 0.2 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Met_10 PF02475.11 GAK62369.1 - 1.8e-52 177.8 0.0 5.8e-46 156.6 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein ISG65-75 PF11727.3 GAK62369.1 - 0.07 12.1 0.5 0.11 11.4 0.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1076 PF06416.7 GAK62369.1 - 0.08 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1076) Fungal_trans PF04082.13 GAK62370.1 - 8.2e-12 44.5 0.2 1.7e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK62370.1 - 3.7e-06 26.7 9.2 7e-06 25.8 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 GAK62370.1 - 0.84 7.8 12.8 5.4 5.1 8.4 2.0 2 0 0 2 2 2 0 Transmembrane protein UCH PF00443.24 GAK62372.1 - 1.1e-45 155.9 0.0 1.6e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAK62372.1 - 1.9e-25 88.7 7.8 4.9e-19 68.2 1.2 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 GAK62372.1 - 7.4e-19 67.0 1.2 3.7e-09 36.1 0.2 2.4 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 GAK62372.1 - 1.4e-17 64.0 0.0 1.1e-16 61.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 GAK62372.1 - 0.042 13.3 0.2 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Pex2_Pex12 PF04757.9 GAK62373.1 - 1.8e-48 164.9 0.4 2.3e-48 164.5 0.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 GAK62373.1 - 2.1e-06 27.6 1.7 3.3e-06 26.9 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK62373.1 - 9.5e-05 21.9 1.1 0.00016 21.3 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK62373.1 - 0.00045 20.0 4.5 0.0016 18.1 3.1 1.8 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAK62373.1 - 0.011 15.4 0.9 0.017 14.7 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAK62373.1 - 0.059 13.2 4.1 0.1 12.4 2.9 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 GAK62374.1 - 0.00087 18.9 7.3 0.0014 18.2 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK62374.1 - 0.053 13.5 11.6 0.082 12.9 8.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK62374.1 - 0.055 13.1 11.1 0.086 12.5 7.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 GAK62374.1 - 4.7 6.3 6.9 7.5 5.6 4.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Ras PF00071.17 GAK62375.1 - 3.6e-52 176.0 0.0 4.6e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK62375.1 - 6.1e-15 55.7 0.0 9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK62375.1 - 3.6e-06 26.3 0.0 5.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Peptidase_S28 PF05577.7 GAK62376.1 - 5.7e-39 133.8 0.0 6.8e-35 120.4 0.0 2.6 2 1 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 GAK62376.1 - 0.0012 18.8 0.6 0.0033 17.3 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Brix PF04427.13 GAK62377.1 - 1.2e-27 96.7 0.0 3e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 Brix domain BUD22 PF09073.5 GAK62377.1 - 0.22 10.5 17.5 0.32 10.0 12.2 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.7 GAK62377.1 - 7.8 5.6 11.8 12 5.0 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.27 GAK62378.1 - 3.8e-22 77.2 12.0 8e-07 28.7 0.9 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 GAK62378.1 - 0.0043 15.2 3.4 0.52 8.3 0.1 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 CLTH PF10607.4 GAK62379.1 - 9.8e-21 73.9 0.0 1.6e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAK62379.1 - 0.0062 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 LisH PTCB-BRCT PF12738.2 GAK62380.1 - 2.9e-35 119.9 0.0 1.2e-13 50.6 0.0 4.6 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 GAK62380.1 - 6.4e-31 106.3 0.0 3.2e-11 43.1 0.0 5.4 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain CENP-C_C PF11699.3 GAK62380.1 - 7e-29 99.6 0.0 1.2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 GAK62380.1 - 0.0075 15.7 0.0 0.021 14.2 0.0 1.8 1 0 0 1 1 1 1 Cupin domain tRNA_Me_trans PF03054.11 GAK62381.1 - 7.3e-106 353.7 0.0 1.3e-105 352.8 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 GAK62381.1 - 0.0026 16.7 0.1 0.26 10.1 0.0 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.8 GAK62381.1 - 0.13 11.5 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 GAK62381.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Tom37_C PF11801.3 GAK62382.1 - 3.2e-07 30.3 0.1 0.0092 15.8 0.0 3.1 3 0 0 3 3 3 2 Tom37 C-terminal domain TFIIA PF03153.8 GAK62382.1 - 5.2e-05 23.3 4.5 5.9e-05 23.1 3.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tom37 PF10568.4 GAK62382.1 - 0.00054 20.1 0.4 0.0021 18.2 0.1 2.2 2 1 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 GAK62382.1 - 0.017 15.5 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SDA1 PF05285.7 GAK62382.1 - 5.6 6.1 16.9 8.1 5.6 11.7 1.2 1 0 0 1 1 1 0 SDA1 Lactonase PF10282.4 GAK62383.1 - 7.8e-15 54.7 0.9 2.1e-13 50.0 0.1 2.1 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller AMP-binding PF00501.23 GAK62387.1 - 3.3e-47 160.8 0.0 4.7e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK62387.1 - 0.01 16.7 0.0 0.025 15.5 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Synaptobrevin PF00957.16 GAK62388.1 - 3e-24 84.4 0.1 4.3e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAK62388.1 - 2.6e-21 74.9 0.0 5.5e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain T4SS PF07996.6 GAK62388.1 - 0.049 13.4 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins IstB_IS21_ATP PF08483.6 GAK62388.1 - 0.13 11.9 0.2 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal TFIIA PF03153.8 GAK62388.1 - 1.4 8.7 15.3 2.2 8.0 10.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.9 GAK62388.1 - 9.1 5.5 7.7 18 4.6 5.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ApbA_C PF08546.6 GAK62389.1 - 1.3e-26 93.0 0.0 2.3e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAK62389.1 - 1.3e-20 73.3 0.0 2.6e-20 72.4 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Sec63 PF02889.11 GAK62390.1 - 3.9e-83 279.2 0.0 8.9e-83 278.0 0.0 1.6 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.24 GAK62390.1 - 1.4e-42 145.0 0.4 2.4e-30 105.2 0.1 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 GAK62390.1 - 1.9e-11 44.1 0.0 2.4e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAK62390.1 - 8.1e-07 28.8 0.1 1.4e-05 24.8 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAK62390.1 - 1.5e-05 25.1 0.1 0.016 15.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 GAK62390.1 - 7.9e-05 21.6 0.1 0.071 11.9 0.0 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 GAK62390.1 - 0.00044 19.7 0.2 0.84 9.0 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_29 PF13555.1 GAK62390.1 - 0.0017 17.8 0.0 0.02 14.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 GAK62390.1 - 0.002 17.6 0.1 0.18 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain SNF2_N PF00176.18 GAK62390.1 - 0.0045 15.8 0.0 0.0097 14.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.11 GAK62390.1 - 0.012 14.9 0.1 4 6.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 GAK62390.1 - 0.074 12.9 1.6 0.65 9.8 0.0 3.4 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 GAK62390.1 - 0.092 12.4 0.1 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Homeobox PF00046.24 GAK62391.1 - 3.2e-12 45.8 1.0 1e-11 44.2 0.7 2.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAK62391.1 - 0.0027 17.3 0.0 0.011 15.4 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain Peptidase_M28 PF04389.12 GAK62392.1 - 1.2e-35 122.9 1.6 1.7e-35 122.3 1.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 NPR2 PF06218.6 GAK62393.1 - 2.9e-99 332.6 0.0 2.4e-44 151.7 0.0 4.2 3 1 1 4 4 4 4 Nitrogen permease regulator 2 Acetyltransf_1 PF00583.19 GAK62393.1 - 6.1e-12 45.4 0.1 1.4e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HhH-GPD PF00730.20 GAK62393.1 - 1.9e-10 40.9 0.0 5.4e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Acetyltransf_7 PF13508.1 GAK62393.1 - 9e-05 22.5 0.1 0.00019 21.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK62393.1 - 0.00046 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein RCR PF12273.3 GAK62394.1 - 0.031 14.8 1.2 0.071 13.6 0.6 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Mucin PF01456.12 GAK62394.1 - 0.063 13.0 17.6 0.13 12.0 12.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein PH_11 PF15413.1 GAK62394.1 - 0.11 12.7 0.4 0.21 11.8 0.3 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Pol_alpha_B_N PF08418.5 GAK62394.1 - 0.12 11.8 8.8 0.17 11.4 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Mcm10 PF09332.6 GAK62394.1 - 0.72 9.1 4.1 0.92 8.7 2.8 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Rhodanese PF00581.15 GAK62395.1 - 2.1e-11 44.1 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.8 GAK62396.1 - 1.7e-67 227.9 11.3 1.7e-67 227.9 7.8 2.3 2 1 0 2 2 2 1 DNA polymerase phi Pkinase PF00069.20 GAK62397.1 - 8.1e-35 120.2 0.0 1.2e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62397.1 - 2.8e-13 49.5 0.0 4.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Presenilin PF01080.12 GAK62397.1 - 0.23 10.2 2.2 0.34 9.7 1.5 1.1 1 0 0 1 1 1 0 Presenilin Coa1 PF08695.5 GAK62398.1 - 7.3e-27 93.2 0.1 9e-27 92.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 UPF0197 PF05251.7 GAK62398.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) SNARE_assoc PF09335.6 GAK62399.1 - 3.2e-16 59.6 9.5 3.2e-16 59.6 6.6 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4149 PF13664.1 GAK62399.1 - 3.1 7.9 11.1 0.31 11.1 0.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Lipase_3 PF01764.20 GAK62400.1 - 4.8e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 GAK62400.1 - 0.00091 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family VEFS-Box PF09733.4 GAK62401.1 - 0.043 13.4 3.2 0.09 12.4 2.2 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein RRM_1 PF00076.17 GAK62402.1 - 6.8e-23 80.0 0.0 2.1e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 GAK62402.1 - 1.1e-21 74.9 0.0 0.00036 19.8 0.0 6.6 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 GAK62402.1 - 3e-16 59.1 0.0 4e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK62402.1 - 1.8e-13 50.1 0.1 1.1e-06 28.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy_2 PF13532.1 GAK62403.1 - 1.2e-13 51.3 0.0 3.1e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 GAK62405.1 - 2.3e-10 40.6 11.3 2.2e-05 24.4 0.6 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAK62405.1 - 5.8e-07 29.3 7.0 5.6e-05 22.8 0.1 2.7 3 0 0 3 3 3 2 KR domain adh_short_C2 PF13561.1 GAK62405.1 - 0.00052 19.8 0.7 0.21 11.3 0.4 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase RNA_polI_A34 PF08208.6 GAK62406.1 - 2.4e-08 33.8 5.9 0.00096 18.8 3.2 2.5 1 1 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 Biotin_lipoyl PF00364.17 GAK62407.1 - 2.8e-21 74.9 2.8 6.3e-21 73.7 2.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 GAK62407.1 - 1.7e-08 33.9 0.0 4.7e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 GAK62407.1 - 5.2e-07 29.2 2.5 2e-05 24.1 0.0 3.1 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD PF00529.15 GAK62407.1 - 0.015 14.5 1.2 0.056 12.7 0.1 2.2 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.2 GAK62407.1 - 0.11 11.5 0.5 2.3 7.2 0.3 2.1 1 1 0 1 1 1 0 HlyD family secretion protein QRPTase_N PF02749.11 GAK62407.1 - 0.11 12.2 0.1 0.46 10.3 0.0 1.9 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain zf-C2H2 PF00096.21 GAK62408.1 - 1.4e-21 75.4 44.1 1e-05 25.5 0.2 9.2 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK62408.1 - 1.4e-21 75.6 21.1 5.5e-08 32.7 2.5 8.8 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAK62408.1 - 1.1e-06 28.5 57.4 0.00036 20.6 0.4 9.2 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAK62408.1 - 1.4e-06 28.2 12.0 0.00063 19.8 0.1 4.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAK62408.1 - 0.059 13.5 0.4 0.059 13.5 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAK62408.1 - 0.5 10.5 16.2 0.07 13.2 1.0 4.6 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 GAK62408.1 - 9 6.3 24.9 0.083 12.8 0.4 5.5 6 0 0 6 6 6 0 C2H2-type zinc finger DUF498 PF04430.9 GAK62409.1 - 7.2e-24 83.4 0.0 1.8e-23 82.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Mito_carr PF00153.22 GAK62410.1 - 2e-44 149.1 3.0 4.8e-16 58.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein GCV_H PF01597.14 GAK62412.1 - 9.1e-44 148.0 0.1 1.1e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 GAK62412.1 - 3.1e-05 23.4 0.2 5.7e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 GAK62412.1 - 0.00017 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 GAK62412.1 - 0.019 14.5 0.9 1.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like Radical_SAM PF04055.16 GAK62413.1 - 1.2e-15 58.0 0.1 3.5e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 GAK62413.1 - 1.3e-10 41.1 0.0 3.9e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAK62413.1 - 0.0091 16.1 0.0 0.03 14.4 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK62413.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RINGv PF12906.2 GAK62414.1 - 1.3e-12 47.5 4.4 1.9e-12 46.9 3.0 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 GAK62414.1 - 0.015 15.1 2.4 0.025 14.4 1.7 1.3 1 0 0 1 1 1 0 Ring finger domain Fasciclin PF02469.17 GAK62415.1 - 4e-56 188.4 0.2 7e-13 48.6 0.0 7.0 7 1 0 7 7 7 6 Fasciclin domain adh_short PF00106.20 GAK62416.1 - 5.6e-29 101.1 0.0 7.3e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK62416.1 - 1.8e-12 47.5 0.0 2.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK62416.1 - 4.9e-12 45.8 0.0 8.7e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAK62416.1 - 1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAK62416.1 - 5.4e-05 22.4 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAK62416.1 - 0.00022 21.2 0.1 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAK62416.1 - 0.0033 17.1 0.1 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAK62416.1 - 0.0047 16.0 0.0 0.009 15.0 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 GAK62416.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAK62416.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GAS2 PF02187.12 GAK62417.1 - 1.6e-08 34.2 0.0 3.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF736 PF05284.7 GAK62417.1 - 0.088 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF736) RRM_6 PF14259.1 GAK62418.1 - 8.8e-14 51.2 0.0 8e-11 41.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK62418.1 - 1.2e-11 44.0 0.0 7.7e-11 41.4 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK62418.1 - 1.2e-10 41.0 0.0 1.5e-06 27.9 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.2 GAK62419.1 - 3.6e-15 56.4 4.9 3.6e-15 56.4 3.4 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK62419.1 - 4.7e-08 32.9 0.7 3e-07 30.3 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK62419.1 - 4.7e-08 32.8 0.0 1.3e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAK62419.1 - 0.044 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DPBB_1 PF03330.13 GAK62420.1 - 0.00028 20.8 1.4 0.00037 20.4 0.0 2.0 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF1183 PF06682.7 GAK62420.1 - 1.4 8.4 18.1 2.5 7.6 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Utp14 PF04615.8 GAK62420.1 - 3.6 5.6 25.6 4.7 5.2 17.7 1.0 1 0 0 1 1 1 0 Utp14 protein Herpes_LMP2 PF07415.6 GAK62420.1 - 6.7 5.1 7.6 11 4.5 5.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein KIAA1328 PF15369.1 GAK62420.1 - 7.5 6.2 12.6 12 5.6 8.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Atrophin-1 PF03154.10 GAK62420.1 - 8.5 4.3 21.4 12 3.8 14.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Cellulase PF00150.13 GAK62421.1 - 1.8e-08 33.9 0.0 6.6e-06 25.5 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Ndc80_HEC PF03801.8 GAK62422.1 - 1e-38 132.2 0.0 4.3e-38 130.2 0.0 2.0 2 0 0 2 2 2 1 HEC/Ndc80p family Flag1_repress PF03614.8 GAK62422.1 - 0.023 14.2 0.5 0.047 13.2 0.4 1.5 1 0 0 1 1 1 0 Repressor of phase-1 flagellin DUF2031 PF09592.5 GAK62422.1 - 0.05 12.7 7.0 0.11 11.6 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) GAS PF13851.1 GAK62422.1 - 4.4 6.4 38.7 0.66 9.1 2.0 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CAP_N PF01213.14 GAK62423.1 - 3.6e-92 308.9 23.8 3.6e-92 308.9 16.5 3.4 3 1 0 3 3 3 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 GAK62423.1 - 3.6e-61 205.1 2.1 4.9e-61 204.7 1.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 GAK62423.1 - 0.0013 18.1 1.2 0.0024 17.2 0.8 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C F-box-like PF12937.2 GAK62423.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.9 1 1 0 1 1 1 0 F-box-like FAD_binding_9 PF08021.6 GAK62423.1 - 0.02 14.8 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Ribosomal_60s PF00428.14 GAK62424.1 - 1.8e-23 82.7 11.7 1.8e-23 82.7 8.1 2.3 2 1 0 2 2 2 1 60s Acidic ribosomal protein ACP PF06857.6 GAK62424.1 - 0.03 14.2 0.8 0.072 13.0 0.1 1.9 2 1 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) Etmic-2 PF06670.6 GAK62424.1 - 0.23 10.1 7.2 0.035 12.8 2.4 1.4 1 1 0 1 1 1 0 Microneme protein Etmic-2 Mito_carr PF00153.22 GAK62425.1 - 5.8e-57 189.4 0.9 1.9e-20 72.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF_assoc_1 PF08355.7 GAK62427.1 - 0.0025 17.0 0.0 0.0044 16.2 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_4 PF12763.2 GAK62427.1 - 0.041 13.6 0.0 0.19 11.4 0.0 2.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DEAD PF00270.24 GAK62428.1 - 4e-31 107.7 0.0 7.3e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK62428.1 - 1.9e-24 85.2 0.0 8.1e-24 83.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4137 PF13593.1 GAK62428.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) WD40 PF00400.27 GAK62429.1 - 1.9e-05 24.3 13.1 0.064 13.1 0.0 8.4 9 0 0 9 9 9 1 WD domain, G-beta repeat CENP-B_dimeris PF09026.5 GAK62429.1 - 0.012 15.8 4.0 0.033 14.4 2.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 GAK62429.1 - 0.3 10.7 6.5 0.56 9.8 4.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.6 GAK62429.1 - 0.37 10.5 1.0 0.77 9.5 0.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 GAK62429.1 - 0.81 8.3 8.3 1.6 7.3 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 GAK62429.1 - 1.2 7.5 3.1 1.9 6.8 2.1 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 GAK62429.1 - 2.4 5.9 3.9 3.4 5.4 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family PQQ_3 PF13570.1 GAK62429.1 - 3.7 7.9 9.3 0.43 10.9 0.1 4.2 6 0 0 6 6 6 0 PQQ-like domain Ribosomal_S6 PF01250.12 GAK62430.1 - 4.7e-13 48.7 0.0 5.6e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Response_reg PF00072.19 GAK62431.1 - 2.3e-21 75.8 0.0 3.9e-15 55.8 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain Tup_N PF08581.5 GAK62434.1 - 0.19 11.9 16.1 0.59 10.3 2.2 3.6 3 0 0 3 3 3 0 Tup N-terminal DivIVA PF05103.8 GAK62434.1 - 1.4 8.9 20.9 0.58 10.2 7.7 3.2 2 1 0 2 2 2 0 DivIVA protein UPF1_Zn_bind PF09416.5 GAK62435.1 - 2e-73 245.0 9.3 4e-73 244.0 5.1 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 GAK62435.1 - 1.4e-58 197.5 0.0 2.7e-58 196.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAK62435.1 - 5.2e-55 186.5 0.9 8.1e-55 185.9 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAK62435.1 - 6.2e-13 48.3 0.1 1.8e-12 46.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAK62435.1 - 1.7e-12 47.3 0.0 3.7e-11 42.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 GAK62435.1 - 6e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 GAK62435.1 - 0.00012 21.7 0.2 0.86 9.0 0.0 3.2 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAK62435.1 - 0.00065 18.7 1.1 0.0029 16.6 0.0 2.4 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 GAK62435.1 - 0.0016 18.1 0.0 0.0033 17.0 0.0 1.6 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 GAK62435.1 - 0.0024 17.1 0.0 0.0077 15.5 0.0 1.7 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 GAK62435.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 GAK62435.1 - 0.045 12.6 0.0 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 GAK62435.1 - 0.058 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.24 GAK62435.1 - 0.078 12.4 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 GAK62435.1 - 0.093 11.9 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 GAK62435.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 GAK62435.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S13_N PF08069.7 GAK62435.1 - 0.14 11.9 0.0 0.46 10.3 0.0 1.9 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 GAK62435.1 - 0.19 10.8 0.0 0.5 9.4 0.0 1.6 2 0 0 2 2 2 0 KaiC Cellulase PF00150.13 GAK62436.1 - 5.9e-18 65.0 0.1 5.9e-18 65.0 0.1 1.3 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SYF2 PF08231.7 GAK62437.1 - 4.3e-40 137.3 18.4 8.1e-40 136.4 12.8 1.4 1 0 0 1 1 1 1 SYF2 splicing factor Smg4_UPF3 PF03467.10 GAK62438.1 - 9.3e-30 103.9 0.0 2.5e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 Smg-4/UPF3 family Gtr1_RagA PF04670.7 GAK62439.1 - 6.9e-87 290.4 0.0 9.2e-87 290.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 GAK62439.1 - 5.3e-06 25.9 0.0 9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAK62439.1 - 0.00026 20.2 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK62439.1 - 0.00028 20.8 0.0 0.00097 19.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAK62439.1 - 0.0027 18.1 0.0 0.0088 16.5 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Zeta_toxin PF06414.7 GAK62439.1 - 0.0052 15.9 0.3 0.14 11.2 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin PduV-EutP PF10662.4 GAK62439.1 - 0.023 14.1 0.2 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 GAK62439.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 GAK62439.1 - 0.043 14.1 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Formyl_trans_N PF00551.14 GAK62440.1 - 1.7e-36 125.4 0.0 2.4e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 GAK62440.1 - 1e-06 28.0 0.0 2.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 GAK62440.1 - 1.7e-05 24.4 0.0 5.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 ACT domain FMO-like PF00743.14 GAK62441.1 - 7.7e-23 80.4 0.0 5.5e-13 47.9 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAK62441.1 - 2.7e-13 50.4 0.0 1.1e-12 48.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK62441.1 - 3.2e-09 36.7 0.0 2.4e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAK62441.1 - 2.4e-08 33.8 2.9 2.7e-08 33.7 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK62441.1 - 5.2e-08 33.0 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAK62441.1 - 4.3e-05 22.6 0.0 0.029 13.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAK62441.1 - 0.00014 20.9 0.5 0.00032 19.7 0.0 1.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAK62441.1 - 0.0037 16.3 0.3 0.0059 15.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK62441.1 - 0.0038 15.7 0.1 0.0054 15.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAK62441.1 - 0.006 15.7 0.1 0.033 13.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 GAK62441.1 - 0.01 16.2 0.1 0.044 14.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAK62441.1 - 0.015 14.4 0.2 0.13 11.3 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 GAK62441.1 - 0.042 12.7 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein E1-E2_ATPase PF00122.15 GAK62444.1 - 3.7e-47 160.3 0.9 9.2e-47 158.9 0.6 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAK62444.1 - 3.7e-42 145.1 2.1 9.5e-42 143.8 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAK62444.1 - 1.1e-28 99.1 0.1 1.4e-14 53.9 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 GAK62444.1 - 2.5e-16 60.4 0.0 8.3e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAK62444.1 - 5.4e-05 22.8 0.7 0.012 15.1 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAK62444.1 - 0.011 15.6 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TGS PF02824.16 GAK62444.1 - 0.097 12.5 0.0 0.46 10.3 0.0 2.1 1 0 0 1 1 1 0 TGS domain DUF1325 PF07039.6 GAK62445.1 - 1.6e-33 115.0 0.0 2.4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain FMN_bind_2 PF04299.7 GAK62447.1 - 8.6e-44 149.0 0.2 1.3e-43 148.4 0.1 1.3 1 0 0 1 1 1 1 Putative FMN-binding domain MIP PF00230.15 GAK62448.1 - 1.2e-50 172.1 16.8 1.6e-50 171.6 11.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 GAK62450.1 - 2.8e-20 72.3 66.8 5.7e-12 45.0 20.2 3.6 2 2 1 3 3 3 2 Major Facilitator Superfamily Tetraspannin PF00335.15 GAK62450.1 - 3.5e-05 23.1 6.2 3.5e-05 23.1 4.3 2.6 2 0 0 2 2 2 1 Tetraspanin family MgtE PF01769.11 GAK62451.1 - 2.7e-23 82.7 35.7 3.3e-09 37.1 1.4 5.1 3 2 1 4 4 4 3 Divalent cation transporter WD40 PF00400.27 GAK62452.1 - 1.1e-60 199.5 17.3 3.1e-11 42.6 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAK62452.1 - 4.4e-08 33.0 0.1 0.0049 16.5 0.0 3.7 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 GAK62452.1 - 0.0014 18.3 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region CAF1A PF12253.3 GAK62453.1 - 1e-22 80.0 8.1 1e-22 80.0 5.6 2.7 1 1 1 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 GAK62453.1 - 8.4e-05 22.0 29.0 8.4e-05 22.0 20.1 3.6 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIA PF03153.8 GAK62453.1 - 0.00011 22.2 20.9 0.00011 22.2 14.5 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit AAA PF00004.24 GAK62454.1 - 3.6e-17 62.7 0.0 1.2e-16 61.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 GAK62454.1 - 5.2e-14 52.2 0.0 2.3e-13 50.1 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 GAK62454.1 - 2.8e-09 36.1 0.1 6.2e-06 25.1 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 GAK62454.1 - 5.3e-09 35.9 0.1 1.3e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 GAK62454.1 - 3.4e-08 33.6 0.6 0.00095 19.3 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.1 GAK62454.1 - 1.4e-05 25.0 0.0 8.4e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 GAK62454.1 - 2.7e-05 23.3 0.0 5.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAK62454.1 - 2.9e-05 23.7 0.1 0.00011 21.9 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 GAK62454.1 - 3.1e-05 24.0 0.0 0.00079 19.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 GAK62454.1 - 4.7e-05 23.0 0.1 0.00012 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAK62454.1 - 0.00062 19.4 0.1 0.0024 17.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAK62454.1 - 0.00077 18.6 0.1 0.025 13.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 GAK62454.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAK62454.1 - 0.0045 16.6 0.0 0.03 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAK62454.1 - 0.0066 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAK62454.1 - 0.009 15.4 0.5 0.027 13.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAK62454.1 - 0.0091 15.4 0.0 0.17 11.2 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA_3 PF07726.6 GAK62454.1 - 0.014 14.9 0.2 0.057 13.0 0.0 2.1 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 GAK62454.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 GAK62454.1 - 0.018 14.5 0.2 0.27 10.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 GAK62454.1 - 0.023 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAK62454.1 - 0.028 15.2 0.0 0.067 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 GAK62454.1 - 0.028 14.3 0.0 0.13 12.1 0.0 2.1 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.4 GAK62454.1 - 0.028 13.3 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 GAK62454.1 - 0.031 13.7 0.2 0.27 10.6 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family Parvo_NS1 PF01057.12 GAK62454.1 - 0.031 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 GAK62454.1 - 0.081 12.8 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 GAK62454.1 - 0.083 12.7 0.1 0.32 10.8 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 GAK62454.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 GAK62454.1 - 0.13 10.9 0.0 2.4 6.8 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_23 PF13476.1 GAK62454.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AA_kinase PF00696.23 GAK62455.1 - 5.3e-40 137.4 0.7 7.7e-40 136.9 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 GAK62455.1 - 4.7e-10 39.0 0.0 9e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 PUA domain Aldedh PF00171.17 GAK62456.1 - 2e-124 415.4 0.1 2.5e-124 415.1 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK62456.1 - 0.0062 15.3 0.0 0.043 12.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Gpi1 PF05024.10 GAK62457.1 - 8.1e-40 136.5 5.3 1.2e-39 136.0 3.7 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Vac_ImportDeg PF09783.4 GAK62458.1 - 3.3e-57 192.8 0.0 1.4e-51 174.4 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein DJ-1_PfpI_N PF13587.1 GAK62458.1 - 0.011 15.3 0.0 0.037 13.5 0.0 1.9 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family Spc24 PF08286.6 GAK62459.1 - 4.3e-10 39.3 18.2 2.6e-06 27.1 5.5 3.2 2 1 1 3 3 3 2 Spc24 subunit of Ndc80 Filament PF00038.16 GAK62459.1 - 0.011 15.1 16.9 0.19 11.1 11.8 2.0 1 1 0 1 1 1 0 Intermediate filament protein GAS PF13851.1 GAK62459.1 - 0.1 11.8 13.9 0.14 11.3 9.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sec2p PF06428.6 GAK62459.1 - 0.15 11.9 10.5 0.18 11.6 5.4 2.2 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Spc7 PF08317.6 GAK62459.1 - 0.3 9.6 13.1 0.57 8.7 9.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein RasGAP_C PF03836.10 GAK62459.1 - 0.33 10.6 10.6 0.56 9.8 1.2 2.2 1 1 1 2 2 2 0 RasGAP C-terminus Atg14 PF10186.4 GAK62459.1 - 0.4 9.5 8.3 0.48 9.3 5.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vps51 PF08700.6 GAK62459.1 - 0.63 9.9 8.9 5.8 6.8 0.8 3.3 1 1 2 3 3 3 0 Vps51/Vps67 TMF_DNA_bd PF12329.3 GAK62459.1 - 0.69 9.7 18.2 0.07 12.9 5.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Herpes_UL6 PF01763.11 GAK62459.1 - 0.77 7.8 8.5 1.3 7.1 5.9 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.14 GAK62459.1 - 0.98 7.1 7.9 1.1 6.9 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MutS_III PF05192.13 GAK62459.1 - 1.6 8.4 10.0 5.6 6.6 6.2 1.9 1 1 1 2 2 2 0 MutS domain III YlqD PF11068.3 GAK62459.1 - 2.4 8.2 8.0 4.3 7.3 5.5 1.5 1 1 0 1 1 1 0 YlqD protein DivIVA PF05103.8 GAK62459.1 - 5 7.1 16.3 0.47 10.5 4.8 2.2 1 1 1 2 2 2 0 DivIVA protein TMCO5 PF14992.1 GAK62459.1 - 6.1 5.8 19.1 0.15 11.1 5.5 2.1 1 1 1 2 2 2 0 TMCO5 family DUF342 PF03961.8 GAK62459.1 - 6.4 5.0 8.9 12 4.1 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) ACCA PF03255.9 GAK62459.1 - 7.9 6.0 7.7 2.1 7.9 1.2 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FAD_binding_3 PF01494.14 GAK62462.1 - 4.6e-26 91.7 0.0 7.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAK62462.1 - 3.8e-14 52.3 0.3 3.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAK62462.1 - 1.9e-10 41.0 0.1 5.1e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK62462.1 - 2.6e-05 24.1 0.1 7.7e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK62462.1 - 8.7e-05 22.4 0.1 0.0013 18.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK62462.1 - 0.00015 20.3 0.1 0.062 11.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 GAK62462.1 - 0.00018 21.6 0.1 0.0029 17.7 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAK62462.1 - 0.00033 19.8 0.3 0.00062 18.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK62462.1 - 0.00093 18.1 0.2 0.0043 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 GAK62462.1 - 0.0014 18.0 0.1 0.0027 17.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 GAK62462.1 - 0.0018 16.9 1.2 0.14 10.7 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase AlaDh_PNT_C PF01262.16 GAK62462.1 - 0.0046 16.5 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAK62462.1 - 0.0058 15.5 0.1 0.044 12.6 0.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 GAK62462.1 - 0.0097 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 GAK62462.1 - 0.017 14.2 0.1 0.062 12.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 GAK62462.1 - 0.034 13.0 0.1 0.056 12.3 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A MSC PF09402.5 GAK62464.1 - 2e-84 283.1 0.1 2.6e-84 282.7 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 GAK62464.1 - 1.3e-13 50.2 0.0 3.5e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 HeH/LEM domain Mito_carr PF00153.22 GAK62465.1 - 1.6e-63 210.4 4.3 1.7e-21 75.7 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Sugar_tr PF00083.19 GAK62466.1 - 4.5e-22 78.2 6.2 4.5e-22 78.2 4.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK62466.1 - 3.4e-20 72.0 57.9 1.5e-14 53.5 20.1 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAK62466.1 - 3.9 7.3 8.7 0.066 13.0 0.4 2.4 3 0 0 3 3 3 0 MFS_1 like family HSP9_HSP12 PF04119.7 GAK62467.1 - 1.3e-20 73.1 8.7 3.6e-20 71.7 4.3 2.1 2 0 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.1 GAK62467.1 - 0.55 10.3 10.6 36 4.5 7.4 2.3 1 1 0 1 1 1 0 MT0933-like antitoxin protein E1-E2_ATPase PF00122.15 GAK62468.1 - 3.5e-63 212.7 2.1 3.5e-63 212.7 1.4 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAK62468.1 - 3e-34 118.1 4.2 3e-34 118.1 2.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAK62468.1 - 2.1e-29 103.4 0.0 6.1e-28 98.7 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK62468.1 - 7.6e-18 63.7 0.1 7.6e-18 63.7 0.1 3.5 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAK62468.1 - 8e-18 64.1 0.0 2.5e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAK62468.1 - 4.8e-10 39.9 0.1 1.1e-09 38.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAK62468.1 - 0.0035 16.9 0.1 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1615 PF07759.7 GAK62468.1 - 0.14 10.8 0.1 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) DUF1075 PF06388.6 GAK62469.1 - 0.18 11.4 2.4 3.7 7.1 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) p450 PF00067.17 GAK62470.1 - 4.4e-55 187.0 0.0 8.5e-55 186.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Pro_CA PF00484.14 GAK62471.1 - 6.6e-40 136.6 0.3 1.3e-39 135.6 0.2 1.5 2 0 0 2 2 2 1 Carbonic anhydrase Abhydrolase_6 PF12697.2 GAK62471.1 - 0.0065 16.3 2.8 0.32 10.8 0.6 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK62471.1 - 0.028 13.9 2.0 0.66 9.4 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF4203 PF13886.1 GAK62472.1 - 1.8e-27 96.1 20.5 2.4e-27 95.7 14.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) JAB PF01398.16 GAK62474.1 - 2.4e-05 24.0 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ribosomal_L31e PF01198.14 GAK62475.1 - 5.5e-35 118.8 2.4 5.5e-35 118.8 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L31e Methyltransf_33 PF10017.4 GAK62476.1 - 2.6e-35 121.0 0.0 4.6e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 GAK62476.1 - 1.7e-22 80.0 1.2 6.6e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 dCMP_cyt_deam_1 PF00383.17 GAK62476.1 - 1.2e-20 73.0 0.0 2.1e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAK62476.1 - 0.0001 22.1 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase DinB_2 PF12867.2 GAK62476.1 - 0.00099 19.4 1.5 0.004 17.4 1.0 2.1 1 0 0 1 1 1 1 DinB superfamily Grp1_Fun34_YaaH PF01184.14 GAK62478.1 - 2.9e-82 275.0 17.7 3.3e-82 274.8 12.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Transglycosylas PF06737.9 GAK62478.1 - 5.2 7.4 8.2 6.5 7.1 0.2 3.2 4 0 0 4 4 4 0 Transglycosylase-like domain Zn_clus PF00172.13 GAK62479.1 - 7.9e-06 25.6 4.2 1.5e-05 24.7 2.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bud13 PF09736.4 GAK62483.1 - 2.1e-42 144.8 0.7 3.7e-42 144.0 0.5 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Herpes_LMP2 PF07415.6 GAK62483.1 - 0.15 10.5 1.1 0.23 10.0 0.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein LSM PF01423.17 GAK62484.1 - 9.7e-21 73.1 0.1 1.1e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain NUC153 PF08159.7 GAK62485.1 - 1.3e-12 47.0 10.2 4.1e-10 39.0 0.3 3.7 3 0 0 3 3 3 3 NUC153 domain BLUF PF04940.7 GAK62486.1 - 1.2e-31 108.2 0.0 1.8e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Sensors of blue-light using FAD DUF566 PF04484.7 GAK62486.1 - 7.7 5.9 14.2 11 5.4 9.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Autophagy_N PF03986.8 GAK62487.1 - 5.7e-47 159.1 0.7 9.6e-47 158.4 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 GAK62487.1 - 6.3e-29 99.9 0.0 1.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 GAK62487.1 - 1.3e-13 49.7 0.5 2.2e-13 49.0 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Peptidase_M1 PF01433.15 GAK62488.1 - 5.7e-67 226.4 0.0 8.7e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 IPPT PF01715.12 GAK62488.1 - 5.6e-50 169.7 0.1 1.7e-27 96.0 0.1 2.4 1 1 1 2 2 2 2 IPP transferase Leuk-A4-hydro_C PF09127.6 GAK62488.1 - 4.1e-43 146.4 0.0 9.4e-43 145.2 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 GAK62488.1 - 4e-14 52.7 0.0 1.2e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 Peptidase MA superfamily PhoH PF02562.11 GAK62488.1 - 0.0022 17.2 0.1 0.012 14.8 0.3 1.9 2 0 0 2 2 2 1 PhoH-like protein IPT PF01745.11 GAK62488.1 - 0.0059 15.8 0.1 0.033 13.3 0.1 2.1 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 GAK62488.1 - 0.01 16.6 0.1 0.056 14.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 GAK62488.1 - 0.043 13.2 0.2 0.1 11.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 GAK62488.1 - 0.095 11.2 0.3 0.21 10.0 0.1 1.5 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase UPF0079 PF02367.12 GAK62488.1 - 0.19 11.3 0.3 0.64 9.6 0.2 1.9 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 GAK62488.1 - 0.24 10.4 0.0 0.44 9.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 GAK62488.1 - 0.26 11.5 0.9 3.7 7.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.8 GAK62488.1 - 0.33 9.6 0.1 0.53 8.9 0.1 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 GAK62488.1 - 0.4 10.5 3.1 17 5.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain CbiA PF01656.18 GAK62488.1 - 0.4 10.0 0.9 0.84 8.9 0.6 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RecA PF00154.16 GAK62488.1 - 0.52 9.3 1.8 1.2 8.0 0.2 2.2 2 1 1 3 3 3 0 recA bacterial DNA recombination protein Surface_antigen PF11054.3 GAK62489.1 - 0.016 14.5 0.7 0.25 10.6 0.2 2.1 1 1 1 2 2 2 0 Sporozoite TA4 surface antigen Rad21_Rec8_N PF04825.8 GAK62490.1 - 1.4e-27 95.8 0.0 2.5e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 GAK62490.1 - 9.6e-09 34.3 0.6 9.6e-09 34.3 0.4 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 GAK62490.1 - 0.031 13.8 1.1 0.046 13.3 0.0 1.7 2 0 0 2 2 2 0 ScpA/B protein MFS_1 PF07690.11 GAK62491.1 - 2.6e-24 85.5 22.5 1.7e-18 66.4 7.8 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 GAK62491.1 - 3e-15 56.1 1.8 3e-15 56.1 1.3 2.8 3 0 0 3 3 3 1 Nodulin-like DUF543 PF04418.7 GAK62491.1 - 0.055 13.4 0.4 4.5 7.2 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) SH2_2 PF14633.1 GAK62493.1 - 2.1e-69 232.9 0.1 6.9e-69 231.2 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 GAK62493.1 - 7e-26 90.5 1.0 7e-26 90.5 0.7 3.0 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 GAK62493.1 - 4.3e-22 78.1 0.0 8.7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 GAK62493.1 - 4.7e-22 78.1 0.0 1.2e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 GAK62493.1 - 5.5e-20 71.3 26.8 5.5e-20 71.3 18.5 4.6 3 1 1 4 4 4 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 GAK62493.1 - 1.1e-09 38.3 0.3 3.4e-09 36.7 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_3 PF12836.2 GAK62493.1 - 0.0078 16.1 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2 PF00017.19 GAK62493.1 - 0.011 15.5 0.0 0.034 13.9 0.0 1.9 1 0 0 1 1 1 0 SH2 domain B12-binding PF02310.14 GAK62493.1 - 0.13 12.0 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain JAB PF01398.16 GAK62494.1 - 2.5e-20 72.2 0.1 5.9e-20 71.1 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAK62494.1 - 3.2e-13 49.7 0.4 6.6e-13 48.7 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Syja_N PF02383.13 GAK62495.1 - 4.5e-92 308.2 0.1 6.2e-92 307.7 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain GFO_IDH_MocA PF01408.17 GAK62496.1 - 8.4e-13 48.8 0.4 1.6e-12 48.0 0.3 1.6 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.1 GAK62496.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain BING4CT PF08149.6 GAK62497.1 - 6.5e-34 115.2 0.0 8.5e-33 111.7 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 GAK62497.1 - 1.2e-09 37.6 0.0 1.3e-05 24.8 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 GAK62497.1 - 0.00015 20.6 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region DUF947 PF06102.7 GAK62498.1 - 1.6e-48 164.7 18.8 1.6e-48 164.7 13.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF947) DUF2408 PF10303.4 GAK62498.1 - 4.8 7.3 7.6 0.19 11.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) CENP-P PF13096.1 GAK62499.1 - 0.0004 19.7 0.0 0.18 11.1 0.0 2.5 2 0 0 2 2 2 2 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Atg14 PF10186.4 GAK62499.1 - 0.013 14.5 4.2 0.016 14.1 2.3 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 GAK62499.1 - 0.43 10.2 4.9 0.74 9.4 3.4 1.3 1 0 0 1 1 1 0 Mnd1 family Zn_clus PF00172.13 GAK62500.1 - 0.0094 15.8 5.5 0.018 14.9 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 GAK62501.1 - 1.6e-109 367.0 0.1 4.4e-109 365.6 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAK62501.1 - 3.4e-06 26.8 1.2 3.5e-05 23.4 1.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold WD40 PF00400.27 GAK62502.1 - 1.4e-25 88.1 10.3 4.9e-09 35.7 0.7 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 GAK62502.1 - 6.1e-06 25.8 3.0 0.00023 20.7 0.7 2.6 2 1 0 2 2 2 1 PQQ-like domain eIF2A PF08662.6 GAK62502.1 - 0.00057 19.6 0.4 2.1 8.0 0.0 3.6 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 GAK62502.1 - 0.022 14.2 0.0 0.099 12.1 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 GAK62502.1 - 0.066 11.5 0.3 4.5 5.4 0.0 2.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain RAB3GAP2_N PF14655.1 GAK62502.1 - 0.11 11.5 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CRT10 PF08728.5 GAK62502.1 - 0.13 10.2 0.0 0.22 9.4 0.0 1.3 1 0 0 1 1 1 0 CRT10 PQQ_3 PF13570.1 GAK62502.1 - 0.29 11.4 5.6 15 6.0 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain Brix PF04427.13 GAK62503.1 - 1.1e-45 155.7 0.0 1.4e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nucleoplasmin PF03066.10 GAK62503.1 - 1.4 8.4 8.5 3.6 7.1 5.9 1.8 1 0 0 1 1 1 0 Nucleoplasmin COX7C PF02935.11 GAK62504.1 - 1.5e-10 40.6 2.7 2.4e-10 40.0 1.9 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CorA PF01544.13 GAK62505.1 - 2.9e-15 56.0 1.2 1.5e-07 30.7 0.2 3.7 3 1 0 3 3 3 3 CorA-like Mg2+ transporter protein FCH PF00611.18 GAK62506.1 - 5.1e-18 65.0 1.5 9.1e-18 64.2 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAK62506.1 - 1.6e-12 46.5 0.1 3e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAK62506.1 - 5e-11 42.0 0.0 8.8e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAK62506.1 - 8.2e-09 34.8 0.0 2.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Glycos_transf_1 PF00534.15 GAK62507.1 - 9.6e-31 106.4 0.0 3.6e-29 101.3 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAK62507.1 - 1.4e-15 57.7 0.5 4.1e-15 56.2 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 GAK62507.1 - 1.3e-13 51.0 0.0 3.5e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 GAK62507.1 - 4e-12 46.4 0.0 1.1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAK62507.1 - 0.0049 17.1 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2348 PF09807.4 GAK62508.1 - 4.6e-07 29.1 0.0 1.5e-06 27.4 0.0 1.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2348) WD40 PF00400.27 GAK62509.1 - 1.1e-09 37.7 12.3 0.0022 17.8 0.0 7.0 8 0 0 8 8 8 2 WD domain, G-beta repeat eIF2A PF08662.6 GAK62509.1 - 3.2e-05 23.7 0.1 0.45 10.1 0.0 4.5 6 0 0 6 6 6 1 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.16 GAK62509.1 - 0.055 12.0 0.4 31 3.0 0.0 3.7 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 GAK62509.1 - 0.075 12.7 1.9 5.5 6.7 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.17 GAK62510.1 - 1.1e-39 133.8 0.1 1e-20 73.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK62510.1 - 5.2e-29 100.0 0.0 4.7e-15 55.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK62510.1 - 2.3e-22 78.5 0.0 1.3e-08 34.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 GAK62510.1 - 9.3e-18 64.2 0.2 2.1e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 GAK62510.1 - 0.00018 21.3 0.1 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 GAK62510.1 - 0.079 12.7 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CAP_GLY PF01302.20 GAK62511.1 - 8.1e-27 92.7 1.0 1.2e-26 92.1 0.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 GAK62511.1 - 1.5e-13 50.8 0.0 8.7e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Acetyltransf_1 PF00583.19 GAK62512.1 - 2e-06 27.7 0.1 3.6e-05 23.6 0.1 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 GAK62512.1 - 5.2e-06 26.9 0.0 0.00011 22.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAK62512.1 - 8.9e-05 22.5 0.1 0.00037 20.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK62512.1 - 0.0034 17.0 0.1 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein GNAT_acetyltr_2 PF13718.1 GAK62512.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_10 PF13673.1 GAK62512.1 - 0.042 13.9 0.0 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SNAP PF14938.1 GAK62514.1 - 6.1e-98 327.4 16.0 6.8e-98 327.2 11.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 GAK62514.1 - 4.1e-06 26.3 18.7 0.048 13.2 3.7 4.4 1 1 3 4 4 4 3 TPR repeat TPR_12 PF13424.1 GAK62514.1 - 0.00061 19.6 16.7 0.035 14.0 0.6 4.4 1 1 4 5 5 5 4 Tetratricopeptide repeat Spatacsin_C PF14649.1 GAK62514.1 - 0.0026 16.6 4.1 0.018 13.9 2.8 2.0 1 1 0 1 1 1 1 Spatacsin C-terminus TPR_7 PF13176.1 GAK62514.1 - 0.18 11.7 13.1 58 3.8 0.2 5.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAK62514.1 - 1 9.0 17.7 11 5.8 1.2 6.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAK62514.1 - 1.8 9.1 18.4 3.7 8.2 0.2 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat LssY_C PF14067.1 GAK62515.1 - 0.043 12.7 0.5 1.3 7.9 0.3 2.2 2 0 0 2 2 2 0 LssY C-terminus ELO PF01151.13 GAK62516.1 - 3.2e-63 213.3 9.2 4e-63 213.0 6.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PK PF00224.16 GAK62517.1 - 3.5e-160 532.3 5.6 4.3e-160 532.0 3.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 GAK62517.1 - 8.8e-31 105.8 0.0 2.3e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 GAK62517.1 - 0.00029 19.7 0.4 0.001 18.0 0.2 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 GAK62517.1 - 0.0073 15.2 0.2 0.12 11.1 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Phage_Gp15 PF06854.6 GAK62517.1 - 0.05 13.1 0.1 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Gp15 protein Endonuc-PvuII PF09225.5 GAK62517.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII 2OG-FeII_Oxy_2 PF13532.1 GAK62519.1 - 3.8e-24 85.5 0.0 6.4e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAK62519.1 - 2.2e-06 27.8 0.0 4.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-AN1 PF01428.11 GAK62520.1 - 1.4e-16 60.0 32.5 2.6e-08 33.6 6.8 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 GAK62520.1 - 0.011 15.9 16.7 0.45 10.7 4.1 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain CDC27 PF09507.5 GAK62520.1 - 0.66 9.1 10.9 0.9 8.6 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 COesterase PF00135.23 GAK62521.1 - 1.7e-75 254.7 0.1 2.5e-75 254.2 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAK62521.1 - 4e-12 46.1 0.6 3.5e-11 43.0 0.2 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAK62521.1 - 8.4e-05 21.8 0.4 0.00016 20.9 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAK62521.1 - 0.0017 18.1 0.4 0.0038 16.9 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3674 PF12426.3 GAK62521.1 - 0.32 10.4 0.6 0.63 9.5 0.4 1.4 1 0 0 1 1 1 0 RNA dependent RNA polymerase ESSS PF10183.4 GAK62522.1 - 5.8e-26 90.9 0.9 9.7e-26 90.2 0.6 1.3 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PH PF00169.24 GAK62523.1 - 2.6e-37 127.1 0.0 1.6e-19 69.9 0.6 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 GAK62523.1 - 5.3e-20 71.7 8.2 2.8e-09 37.2 3.1 4.3 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 GAK62523.1 - 9.6e-18 63.9 5.2 6.9e-09 35.5 1.0 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 GAK62523.1 - 1.2e-09 38.1 3.9 6.2e-07 29.3 1.0 2.6 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 GAK62523.1 - 0.00015 21.9 0.5 0.088 12.9 0.6 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain Mcp5_PH PF12814.2 GAK62523.1 - 0.00088 19.1 1.2 2.8 7.8 0.0 3.2 3 0 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.1 GAK62523.1 - 0.0019 17.7 1.6 3.6 7.0 0.0 3.4 2 1 0 3 3 3 2 Pleckstrin homology domain PH_7 PF15408.1 GAK62523.1 - 0.019 14.8 0.1 0.049 13.5 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Cation_efflux PF01545.16 GAK62524.1 - 6.6e-49 166.5 1.0 8.7e-49 166.1 0.7 1.2 1 0 0 1 1 1 1 Cation efflux family adh_short PF00106.20 GAK62525.1 - 3.9e-64 215.5 9.1 9.8e-33 113.4 0.4 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAK62525.1 - 1.7e-33 115.7 4.3 8.6e-17 61.3 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 GAK62525.1 - 3.5e-31 107.1 0.0 6.5e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAK62525.1 - 1.4e-07 31.3 0.0 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 GAK62525.1 - 6.6e-05 22.0 0.1 0.016 14.3 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 GAK62525.1 - 0.015 14.9 6.6 0.36 10.4 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 GAK62525.1 - 0.021 14.6 0.8 0.77 9.5 0.0 2.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF543 PF04418.7 GAK62525.1 - 0.044 13.7 4.4 4.3 7.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Nro1 PF12753.2 GAK62525.1 - 0.4 9.5 1.4 0.66 8.8 1.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Sec7 PF01369.15 GAK62526.1 - 1.4e-39 135.7 0.3 2.4e-39 134.9 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 GAK62526.1 - 1.6e-13 50.8 0.0 3.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAK62526.1 - 1.6e-10 41.1 0.0 3.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 GAK62526.1 - 0.0017 18.3 0.1 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Tom7 PF08038.7 GAK62527.1 - 8.7e-16 57.1 0.1 2.2e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 TOM7 family Prominin PF05478.6 GAK62527.1 - 0.28 8.6 5.5 0.5 7.8 3.8 1.3 1 0 0 1 1 1 0 Prominin Apc5 PF12862.2 GAK62528.1 - 5.2e-12 45.4 3.0 1.1e-11 44.4 0.2 3.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 DUF3730 PF12530.3 GAK62528.1 - 7.5e-09 35.8 6.0 2.5e-08 34.1 1.8 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) TPR_12 PF13424.1 GAK62528.1 - 0.038 13.9 10.6 0.07 13.0 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAK62528.1 - 0.043 13.7 0.3 6.5 6.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAK62528.1 - 0.048 13.4 0.4 2.5 8.0 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat 4HBT PF03061.17 GAK62529.1 - 0.00093 19.2 0.2 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily APH PF01636.18 GAK62530.1 - 6.5e-06 26.0 0.1 0.00058 19.6 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 GAK62530.1 - 1e-05 24.8 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 GAK62530.1 - 1e-05 24.6 0.0 7.2e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAK62530.1 - 0.0039 16.5 0.0 0.26 10.5 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 GAK62530.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase EcKinase PF02958.15 GAK62530.1 - 0.18 10.8 0.0 0.53 9.3 0.0 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase Fasciclin PF02469.17 GAK62531.1 - 1.1e-23 83.6 4.0 1.6e-16 60.4 0.2 2.3 2 0 0 2 2 2 2 Fasciclin domain YopH_N PF09013.5 GAK62531.1 - 8.5 6.0 8.5 0.22 11.2 0.1 2.7 4 0 0 4 4 4 0 YopH, N-terminal Sec61_beta PF03911.11 GAK62532.1 - 8.5e-18 63.8 1.4 1.1e-17 63.5 0.9 1.1 1 0 0 1 1 1 1 Sec61beta family CHCH PF06747.8 GAK62533.1 - 2.8e-06 27.0 1.1 3.6e-06 26.7 0.7 1.1 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 GAK62533.1 - 0.0007 19.3 0.8 0.00093 18.9 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like HTH_5 PF01022.15 GAK62533.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Spc7 PF08317.6 GAK62534.1 - 3.6e-30 104.7 4.1 6.2e-30 103.9 2.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2605 PF10792.4 GAK62534.1 - 0.056 13.1 0.9 0.22 11.2 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) COG5 PF10392.4 GAK62534.1 - 0.058 13.3 5.0 0.18 11.7 3.5 1.9 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF1789 PF08748.6 GAK62534.1 - 6.9 6.7 12.1 0.062 13.4 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1789) Dus PF01207.12 GAK62535.1 - 7.1e-46 156.4 0.1 1.7e-45 155.2 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 GAK62535.1 - 0.0032 16.4 0.0 0.0056 15.6 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase TDH PF03347.8 GAK62535.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Spt5-NGN PF03439.8 GAK62536.1 - 2e-20 72.2 0.0 3.8e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 GAK62536.1 - 9.4e-19 66.3 3.5 4.2e-07 29.4 0.0 5.7 5 0 0 5 5 5 3 KOW motif Spt5_N PF11942.3 GAK62536.1 - 1.4e-15 57.6 54.3 4e-15 56.2 12.3 2.5 2 0 0 2 2 2 2 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 GAK62536.1 - 6.8e-09 36.2 14.0 6.8e-09 36.2 9.7 2.3 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Tox-HDC PF15656.1 GAK62536.1 - 0.017 15.3 0.1 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature YajC PF02699.10 GAK62536.1 - 0.33 10.6 2.0 1.3 8.7 0.1 2.7 2 1 1 3 3 3 0 Preprotein translocase subunit Daxx PF03344.10 GAK62536.1 - 7.4 4.9 27.8 11 4.3 19.3 1.1 1 0 0 1 1 1 0 Daxx Family GTP_EFTU PF00009.22 GAK62537.1 - 1e-58 197.8 0.2 1.5e-58 197.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAK62537.1 - 1.5e-29 102.0 0.0 3.7e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAK62537.1 - 7.3e-17 61.2 3.1 1.8e-16 59.9 2.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 GAK62537.1 - 3.3e-05 23.4 0.6 7e-05 22.3 0.4 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 GAK62537.1 - 5.4e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 GAK62537.1 - 0.047 13.1 0.8 0.099 12.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 GAK62537.1 - 0.059 12.8 0.3 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 GAK62537.1 - 0.09 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein zf-SNAP50_C PF12251.3 GAK62538.1 - 1.3e-11 44.2 0.0 2.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C2H2 PF00096.21 GAK62539.1 - 2.4e-32 109.2 63.1 0.00011 22.3 0.1 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK62539.1 - 2.5e-23 80.6 68.6 0.0028 17.8 0.2 10.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAK62539.1 - 1.8e-11 43.7 54.8 2.8e-07 30.4 0.1 11.1 13 1 0 13 13 13 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 GAK62539.1 - 0.017 15.0 21.8 0.48 10.4 0.1 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger IBR PF01485.16 GAK62539.1 - 0.45 10.4 24.9 5.6 6.9 0.4 6.1 3 1 1 5 5 5 0 IBR domain FYDLN_acid PF09538.5 GAK62539.1 - 0.67 10.5 21.6 0.26 11.8 0.6 5.2 5 1 1 6 6 6 0 Protein of unknown function (FYDLN_acid) zf-C2H2_jaz PF12171.3 GAK62539.1 - 3.3 7.9 27.4 14 5.9 0.1 8.4 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.11 GAK62539.1 - 6.7 6.6 11.1 1.1 9.2 2.3 3.6 3 0 0 3 3 3 0 AN1-like Zinc finger Acetyltransf_3 PF13302.1 GAK62540.1 - 2.4e-23 82.8 0.0 3.1e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAK62540.1 - 2.6e-06 27.4 0.1 0.00023 21.0 0.1 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAK62540.1 - 0.004 17.1 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.5 GAK62540.1 - 0.036 13.8 0.0 0.08 12.7 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_4 PF13420.1 GAK62540.1 - 0.096 12.6 0.0 9.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Apolipoprotein PF01442.13 GAK62541.1 - 9.2e-08 31.8 28.8 0.0035 16.8 0.2 5.0 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 GAK62541.1 - 6.1e-06 26.5 93.5 0.059 13.7 0.7 10.8 1 1 9 10 10 10 6 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 GAK62541.1 - 0.012 16.0 1.8 0.012 16.0 1.2 9.2 2 1 1 3 3 3 0 YtxH-like protein ApoO PF09769.4 GAK62541.1 - 0.13 11.9 0.1 0.13 11.9 0.1 5.2 3 2 1 5 5 5 0 Apolipoprotein O Prominin PF05478.6 GAK62541.1 - 4.3 4.7 7.7 3.7 4.9 0.8 2.2 2 0 0 2 2 2 0 Prominin PAF-AH_p_II PF03403.8 GAK62542.1 - 4.6e-43 146.9 0.0 2.7e-40 137.8 0.0 4.0 3 1 0 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAK62542.1 - 4.7e-12 45.8 0.0 1.2e-10 41.2 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK62542.1 - 2.8e-07 30.6 0.0 2.3e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAK62542.1 - 8.1e-05 22.3 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 GAK62542.1 - 0.0015 17.5 0.0 0.019 13.8 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAK62542.1 - 0.022 13.5 0.0 0.064 12.0 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase ADH_zinc_N PF00107.21 GAK62544.1 - 2.8e-27 94.8 0.2 4.9e-27 94.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK62544.1 - 5.4e-11 42.2 0.0 2.3e-09 37.0 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAK62544.1 - 1e-10 42.6 0.0 2.8e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2493 PF10686.4 GAK62544.1 - 0.61 9.6 2.8 3 7.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2493) Abhydrolase_2 PF02230.11 GAK62545.1 - 1.2e-55 188.2 0.0 1.4e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAK62545.1 - 6.7e-15 55.1 0.1 9.2e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK62545.1 - 2.7e-10 40.5 0.6 6e-10 39.3 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK62545.1 - 0.00012 21.3 0.3 0.015 14.5 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 GAK62545.1 - 0.001 18.3 0.1 0.26 10.5 0.0 2.2 1 1 1 2 2 2 2 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 GAK62545.1 - 0.0014 18.2 0.2 0.032 13.7 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 GAK62545.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.8 GAK62545.1 - 0.0019 17.6 0.0 0.016 14.6 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 GAK62545.1 - 0.0035 16.6 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 GAK62545.1 - 0.0065 15.0 0.1 0.012 14.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 GAK62545.1 - 0.0094 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 GAK62545.1 - 0.018 14.8 0.0 0.043 13.5 0.0 1.6 2 0 0 2 2 2 0 Cutinase Lipase_3 PF01764.20 GAK62545.1 - 0.025 14.2 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.11 GAK62545.1 - 0.071 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Trypsin_2 PF13365.1 GAK62546.1 - 0.0031 17.5 0.1 0.0086 16.0 0.1 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Abhydrolase_5 PF12695.2 GAK62547.1 - 8.9e-12 44.9 0.1 1.4e-11 44.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAK62547.1 - 5.4e-10 39.2 0.3 8.6e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK62547.1 - 4.9e-08 33.1 0.8 5.3e-08 33.0 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAK62547.1 - 0.00048 19.9 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase COesterase PF00135.23 GAK62547.1 - 0.0025 16.5 0.0 0.0044 15.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF900 PF05990.7 GAK62547.1 - 0.027 13.7 0.0 0.81 8.9 0.0 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.16 GAK62547.1 - 0.068 12.3 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cellulase PF00150.13 GAK62548.1 - 2.1e-13 50.1 0.0 4.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mss4 PF04421.8 GAK62549.1 - 5e-09 35.8 0.0 3.5e-05 23.5 0.0 2.8 2 0 0 2 2 2 2 Mss4 protein Acetyltransf_1 PF00583.19 GAK62549.1 - 4.1e-08 33.1 0.1 1.1e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK62549.1 - 3.6e-06 27.0 0.0 6.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAK62549.1 - 0.007 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK62549.1 - 0.0079 15.9 0.0 0.055 13.2 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein U79_P34 PF03064.11 GAK62549.1 - 0.021 14.3 10.7 0.037 13.5 7.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Acetyltransf_CG PF14542.1 GAK62549.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase BLVR PF06375.6 GAK62549.1 - 0.11 12.3 10.9 0.45 10.3 7.0 2.2 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) NARP1 PF12569.3 GAK62549.1 - 0.2 10.3 12.7 0.37 9.4 8.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 GAK62549.1 - 3.2 7.1 17.6 4.9 6.5 12.2 1.2 1 0 0 1 1 1 0 DDRGK domain DUF1510 PF07423.6 GAK62549.1 - 7.6 5.8 14.4 19 4.5 10.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3724 PF12521.3 GAK62549.1 - 9.9 6.1 8.0 0.41 10.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) Polysacc_deac_1 PF01522.16 GAK62550.1 - 6.2e-14 51.7 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase GFA PF04828.9 GAK62550.1 - 6.9e-09 35.5 1.1 1.3e-07 31.4 0.8 2.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Resistin PF06954.6 GAK62550.1 - 0.22 11.8 2.5 9.1 6.6 0.2 3.2 3 0 0 3 3 3 0 Resistin Usp PF00582.21 GAK62551.1 - 4.6e-17 62.5 1.6 6.3e-17 62.0 1.1 1.2 1 0 0 1 1 1 1 Universal stress protein family FMN_dh PF01070.13 GAK62553.1 - 2e-117 392.0 0.1 2.7e-117 391.6 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAK62553.1 - 1.6e-17 63.0 0.0 3.5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAK62553.1 - 2.1e-05 23.6 0.0 3.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAK62553.1 - 0.00083 18.3 0.2 0.0034 16.3 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 GAK62553.1 - 0.01 15.1 0.0 5.6 6.1 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein Peripla_BP_4 PF13407.1 GAK62553.1 - 0.016 14.6 0.0 0.08 12.2 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein domain A_deaminase_N PF08451.6 GAK62553.1 - 0.034 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Acyl-CoA_dh_1 PF00441.19 GAK62554.1 - 2.1e-15 57.0 5.5 4.1e-15 56.1 0.1 2.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAK62554.1 - 3.4e-08 32.8 0.2 9.3e-08 31.4 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAK62554.1 - 0.02 15.4 0.0 0.22 12.1 0.0 2.6 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAK62554.1 - 0.022 14.9 2.5 0.072 13.3 0.0 2.7 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1770 PF08589.5 GAK62555.1 - 1.6e-09 38.2 0.2 2.3e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) SpoIIE PF07228.7 GAK62556.1 - 7.9e-15 55.0 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 GAK62556.1 - 4.6e-05 22.9 0.1 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 GAK62556.1 - 0.00028 20.3 0.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Metallophos PF00149.23 GAK62557.1 - 7.3e-10 38.5 0.0 4e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UDPG_MGDP_dh_N PF03721.9 GAK62558.1 - 1.5e-57 193.9 0.2 3.9e-56 189.3 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 GAK62558.1 - 4.3e-33 113.6 0.5 3.8e-32 110.6 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 GAK62558.1 - 5e-31 106.7 0.0 1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 GAK62558.1 - 0.028 14.1 0.3 0.87 9.3 0.0 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cas_APE2256 PF09651.5 GAK62558.1 - 0.1 12.3 0.2 8 6.1 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Amidase PF01425.16 GAK62559.1 - 2.5e-81 273.8 0.0 8.8e-80 268.6 0.0 2.1 1 1 0 1 1 1 1 Amidase EutA PF06277.6 GAK62559.1 - 0.28 9.7 0.0 0.45 9.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA MFS_1 PF07690.11 GAK62560.1 - 2.8e-30 105.2 37.9 2.8e-30 105.2 26.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF872 PF05915.7 GAK62560.1 - 0.14 11.9 2.0 2.1 8.2 1.3 2.8 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Aminotran_4 PF01063.14 GAK62561.1 - 1.5e-20 73.6 0.0 4.1e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class IV ADH_zinc_N PF00107.21 GAK62562.1 - 2.7e-11 43.1 0.4 1.4e-10 40.8 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK62562.1 - 5.6e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAK62562.1 - 0.00053 20.8 0.0 0.0014 19.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TFIID-18kDa PF02269.11 GAK62563.1 - 1.1e-28 98.8 0.7 4.9e-28 96.7 0.2 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Fungal_trans PF04082.13 GAK62564.1 - 2.8e-29 101.7 0.1 9.2e-29 100.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK62564.1 - 2.1e-11 43.5 8.8 2.1e-11 43.5 6.1 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 GAK62565.1 - 2.2e-33 112.9 3.7 1.8e-07 30.7 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Prp19 PF08606.6 GAK62565.1 - 1e-30 105.2 1.4 2.1e-30 104.2 1.0 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.3 GAK62565.1 - 0.0072 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF1631 PF07793.6 GAK62565.1 - 0.039 12.0 0.2 0.055 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) eIF2A PF08662.6 GAK62565.1 - 0.2 11.3 0.0 2.7 7.6 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4221 PF13970.1 GAK62565.1 - 0.24 10.6 0.0 0.94 8.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) Mpv17_PMP22 PF04117.7 GAK62566.1 - 5e-11 42.0 4.1 1.6e-09 37.2 1.6 2.3 1 1 1 2 2 2 2 Mpv17 / PMP22 family POR PF01558.13 GAK62566.1 - 0.02 14.8 0.4 0.7 9.7 0.1 2.8 1 1 1 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF1769 PF08588.5 GAK62567.1 - 5.6e-20 71.0 0.6 1.3e-19 69.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Dak1 PF02733.12 GAK62568.1 - 2.8e-108 361.3 0.0 3.7e-108 360.9 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 GAK62568.1 - 1.1e-43 148.8 0.8 1.1e-43 148.8 0.5 2.2 2 0 0 2 2 2 1 DAK2 domain adh_short PF00106.20 GAK62569.1 - 8.2e-30 103.9 0.1 1.5e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK62569.1 - 6.4e-29 101.4 0.0 8.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK62569.1 - 1.1e-14 54.5 0.1 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAK62569.1 - 0.0078 15.6 0.3 0.025 14.0 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAK62569.1 - 0.0085 15.0 0.1 0.012 14.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ATP-synt_S1 PF05827.7 GAK62570.1 - 0.11 11.8 0.8 0.83 8.9 0.0 2.2 2 1 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) FTR1 PF03239.9 GAK62571.1 - 4.8e-53 180.0 7.6 4.5e-35 121.0 3.1 2.1 2 0 0 2 2 2 2 Iron permease FTR1 family Wzy_C PF04932.10 GAK62571.1 - 0.00046 20.0 1.7 0.0042 16.8 0.2 2.4 2 0 0 2 2 2 1 O-Antigen ligase DUF2721 PF11026.3 GAK62571.1 - 0.014 15.0 0.6 0.014 15.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Cu-oxidase_2 PF07731.9 GAK62572.1 - 4.2e-39 133.2 5.6 1.2e-36 125.2 1.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAK62572.1 - 1e-37 129.4 0.1 1.5e-34 119.1 0.0 2.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAK62572.1 - 4.7e-32 110.1 0.7 4.4e-27 94.1 0.1 4.1 4 0 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.1 GAK62572.1 - 0.14 12.1 0.0 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Cupredoxin-like domain PAN_4 PF14295.1 GAK62573.1 - 0.035 13.8 0.1 0.035 13.8 0.1 2.6 2 0 0 2 2 2 0 PAN domain Alpha-amylase PF00128.19 GAK62574.1 - 9e-75 251.9 0.1 1.4e-74 251.3 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAK62574.1 - 7.7e-16 57.9 0.4 2e-15 56.6 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) MFS_1 PF07690.11 GAK62575.1 - 2e-22 79.4 38.8 7e-13 48.0 13.8 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily Neurensin PF14927.1 GAK62575.1 - 0.14 11.4 0.1 0.14 11.4 0.0 3.2 4 0 0 4 4 4 0 Neurensin Glyco_hydro_cc PF11790.3 GAK62576.1 - 2.5e-61 207.1 10.2 4.2e-60 203.1 7.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core IMS PF00817.15 GAK62577.1 - 5e-39 133.4 0.0 9.1e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAK62577.1 - 2.1e-10 40.5 0.1 2e-09 37.4 0.0 2.4 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain MMtag PF10159.4 GAK62578.1 - 6.4e-29 99.8 2.7 6.4e-29 99.8 1.9 2.9 3 0 0 3 3 3 1 Kinase phosphorylation protein CTP_transf_2 PF01467.21 GAK62578.1 - 3.2e-14 53.2 0.3 9.6e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase DUF1479 PF07350.7 GAK62579.1 - 3.8e-05 22.3 0.1 0.00032 19.3 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.1 GAK62579.1 - 0.00014 22.3 0.1 0.0037 17.7 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 GAK62579.1 - 0.00057 19.9 0.0 0.0081 16.2 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 GAK62579.1 - 0.0048 16.6 0.0 0.064 12.9 0.0 2.3 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_5 PF13759.1 GAK62579.1 - 0.023 14.9 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Peptidase_S15 PF02129.13 GAK62580.1 - 8.6e-33 113.9 0.0 1.8e-31 109.5 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAK62580.1 - 8.5e-28 97.7 0.0 1.1e-27 97.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 GAK62580.1 - 0.00052 19.9 0.0 0.00093 19.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 GAK62581.1 - 2e-18 66.2 27.6 2e-18 66.2 19.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAK62582.1 - 1.3e-18 66.8 0.0 2.7e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 GAK62582.1 - 2.1e-05 24.5 19.1 6e-05 23.0 0.2 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAK62582.1 - 2.8e-05 24.1 10.1 0.002 18.3 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 GAK62582.1 - 0.00027 20.7 6.1 0.00027 20.7 4.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC_2 PF13913.1 GAK62582.1 - 0.012 15.2 7.9 0.17 11.5 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 GAK62582.1 - 0.12 12.7 6.3 0.86 10.0 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain TerY-C PF15616.1 GAK62582.1 - 1.3 8.9 4.3 1.3 8.9 0.1 2.6 3 0 0 3 3 3 0 TerY-C metal binding domain Ytp1 PF10355.4 GAK62583.1 - 3.1e-80 269.2 15.4 3.1e-80 269.2 10.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAK62583.1 - 4.8e-29 100.0 2.8 4.8e-29 100.0 2.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3760 PF12586.3 GAK62584.1 - 0.018 14.8 1.6 0.018 14.8 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) Zip PF02535.17 GAK62585.1 - 1.3e-52 178.8 15.6 2e-52 178.1 10.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Sigma70_r4_2 PF08281.7 GAK62585.1 - 1.4e-10 40.4 0.1 9.7e-06 24.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_38 PF13936.1 GAK62585.1 - 2.3e-10 39.8 1.4 9.2e-06 25.1 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.1 GAK62585.1 - 9.7e-09 34.6 0.1 0.0009 18.8 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain GerE PF00196.14 GAK62585.1 - 1.1e-07 30.9 1.2 0.011 15.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.11 GAK62585.1 - 0.00062 19.0 0.1 0.0018 17.5 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Terminase_5 PF06056.7 GAK62585.1 - 0.0011 18.4 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.1 GAK62585.1 - 0.0013 18.9 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 Winged helix-turn helix HTH_28 PF13518.1 GAK62585.1 - 0.0064 16.4 0.0 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.10 GAK62585.1 - 0.013 15.3 0.2 0.067 13.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF2481 PF10654.4 GAK62585.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) HTH_40 PF14493.1 GAK62585.1 - 0.25 11.5 0.1 34 4.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain adh_short PF00106.20 GAK62586.1 - 5.9e-23 81.5 0.0 7.8e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK62586.1 - 1.4e-09 37.8 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK62586.1 - 1.7e-06 28.0 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAK62586.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAK62586.1 - 0.0097 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAK62586.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 GAK62586.1 - 0.015 15.7 0.0 0.038 14.4 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 GAK62586.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.19 GAK62587.1 - 1.3e-24 86.3 0.0 2.2e-24 85.6 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAK62587.1 - 1.9e-16 59.2 0.0 3.6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family MFS_1 PF07690.11 GAK62588.1 - 5.4e-22 77.9 43.9 1.3e-15 56.9 15.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK62588.1 - 5.9e-18 64.6 22.4 2.5e-16 59.2 6.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1840 PF08895.6 GAK62588.1 - 0.38 10.7 3.0 0.79 9.7 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) UPRTase PF14681.1 GAK62589.1 - 1.5e-69 233.3 0.0 1.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAK62589.1 - 0.0019 17.9 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain adh_short PF00106.20 GAK62590.1 - 1.1e-26 93.7 1.8 1.5e-26 93.3 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK62590.1 - 5.9e-24 85.1 1.2 7.6e-24 84.8 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK62590.1 - 1.5e-09 37.8 1.7 3.4e-09 36.6 1.2 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAK62590.1 - 0.018 13.9 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1657 PF07870.6 GAK62590.1 - 0.052 13.2 0.8 0.1 12.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) ThiF PF00899.16 GAK62590.1 - 0.1 12.4 1.4 2.9 7.7 0.2 2.4 1 1 1 2 2 2 0 ThiF family Methyltransf_25 PF13649.1 GAK62590.1 - 0.11 12.8 0.2 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Oxidored-like PF09791.4 GAK62592.1 - 2e-06 27.1 8.9 4.6e-06 25.9 6.2 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Abhydrolase_5 PF12695.2 GAK62592.1 - 3.2e-06 26.9 0.0 9.9e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK62592.1 - 0.024 14.1 0.3 0.15 11.5 0.2 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Smr PF01713.16 GAK62593.1 - 9.8e-12 44.9 1.9 1.4e-11 44.4 0.1 2.1 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 GAK62593.1 - 6.5e-08 31.9 0.2 0.00075 18.9 0.0 4.0 4 0 0 4 4 4 2 CUE domain TRAM_LAG1_CLN8 PF03798.11 GAK62594.1 - 2.2e-30 105.6 10.6 2.8e-30 105.3 7.4 1.1 1 0 0 1 1 1 1 TLC domain RRF PF01765.14 GAK62595.1 - 3e-42 143.9 0.0 4.3e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Abhydrolase_6 PF12697.2 GAK62596.1 - 6e-16 59.0 1.3 1.9e-14 54.0 0.9 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK62596.1 - 8.3e-13 48.3 0.1 2.7e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAK62596.1 - 4.5e-08 32.8 0.0 9.3e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 GAK62596.1 - 6e-05 22.7 0.1 0.0013 18.3 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAK62596.1 - 0.0088 15.2 0.0 0.73 9.0 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAK62596.1 - 0.12 11.7 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAK62596.1 - 0.13 10.7 0.0 0.54 8.6 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) HECT PF00632.20 GAK62597.1 - 6.9e-34 117.4 0.0 3.2e-33 115.2 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Myc_N PF01056.13 GAK62597.1 - 0.046 12.8 9.5 0.071 12.2 6.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Form_Nir_trans PF01226.12 GAK62598.1 - 1.6e-63 213.9 21.0 2.5e-63 213.3 14.5 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter Herpes_Helicase PF02689.9 GAK62598.1 - 0.015 13.1 0.1 0.028 12.1 0.1 1.3 1 0 0 1 1 1 0 Helicase ARGLU PF15346.1 GAK62598.1 - 3.6 7.3 27.8 7.4 6.3 19.3 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Hydantoinase_B PF02538.9 GAK62599.1 - 1.5e-186 620.6 0.0 3.8e-186 619.3 0.0 1.6 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Epimerase PF01370.16 GAK62600.1 - 3.2e-19 69.3 0.0 4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK62600.1 - 3.1e-11 42.5 0.0 4.1e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAK62600.1 - 6.1e-10 38.4 0.0 2.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 GAK62600.1 - 6.5e-09 35.0 0.0 1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAK62600.1 - 5.1e-05 23.2 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAK62600.1 - 0.045 12.6 0.0 0.55 9.0 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAK62600.1 - 0.05 13.6 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Lyase_aromatic PF00221.14 GAK62601.1 - 3.5e-161 536.8 0.8 4.7e-161 536.4 0.6 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase C5-epim_C PF06662.8 GAK62602.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Xan_ur_permease PF00860.15 GAK62605.1 - 6.8e-60 202.5 27.0 6.8e-60 202.5 18.7 1.5 2 0 0 2 2 2 1 Permease family Mob_synth_C PF06463.8 GAK62606.1 - 1.4e-32 112.0 0.0 8.6e-32 109.5 0.0 2.3 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 GAK62606.1 - 2.5e-24 86.3 0.0 4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 GAK62606.1 - 3.8e-07 30.3 0.0 7.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAK62606.1 - 1.4e-06 28.3 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain MoaC PF01967.16 GAK62607.1 - 1.5e-46 157.3 1.0 2.2e-46 156.8 0.7 1.2 1 0 0 1 1 1 1 MoaC family DUF3698 PF12479.3 GAK62607.1 - 0.034 14.2 0.1 0.075 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Nop16 PF09420.5 GAK62608.1 - 1.4e-42 145.5 0.4 1.6e-42 145.4 0.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF775 PF05603.7 GAK62609.1 - 4.4e-39 134.0 0.0 5.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) EXS PF03124.9 GAK62610.1 - 7.3e-73 245.5 0.0 8.7e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 EXS family Abhydrolase_5 PF12695.2 GAK62611.1 - 0.0011 18.7 0.4 0.0011 18.7 0.3 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAK62611.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 GAK62611.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF818 PF05677.7 GAK62611.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DS PF01916.12 GAK62612.1 - 1.4e-133 444.6 0.0 1.6e-133 444.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF494 PF04361.8 GAK62612.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF494) ICE2 PF08426.5 GAK62613.1 - 7.9e-53 179.5 0.2 2.9e-29 101.9 0.0 2.8 2 1 1 3 3 3 2 ICE2 DUF605 PF04652.11 GAK62613.1 - 0.082 12.2 4.0 0.19 11.1 2.8 1.5 1 1 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 GAK62614.1 - 1e-14 54.0 0.0 2.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK62614.1 - 1.7e-07 31.0 8.8 2.9e-07 30.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HisKA_3 PF07730.8 GAK62614.1 - 0.15 12.4 3.9 0.096 13.0 0.3 2.5 2 0 0 2 2 2 0 Histidine kinase AA_permease_2 PF13520.1 GAK62615.1 - 1.8e-44 151.9 41.0 2.4e-44 151.5 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease zf-UBR PF02207.15 GAK62616.1 - 4.2e-16 58.4 15.1 4.2e-16 58.4 10.4 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 GAK62616.1 - 3.2e-10 39.5 0.0 8.6e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UBA_4 PF14555.1 GAK62616.1 - 0.054 13.0 0.1 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain MSP1_C PF07462.6 GAK62616.1 - 0.16 10.2 2.0 0.28 9.5 1.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SET PF00856.23 GAK62617.1 - 5.5e-05 23.5 0.0 0.02 15.1 0.0 3.1 1 1 2 3 3 3 2 SET domain Ribonuc_L-PSP PF01042.16 GAK62618.1 - 2e-37 127.6 0.1 3.2e-37 126.9 0.1 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Asp PF00026.18 GAK62619.1 - 2.4e-45 155.1 15.2 8.6e-45 153.3 10.5 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAK62619.1 - 3.8e-06 27.2 2.6 0.015 15.7 0.7 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 GAK62619.1 - 0.00035 20.5 9.2 0.0076 16.2 3.8 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAK62619.1 - 0.0015 18.1 0.0 0.006 16.1 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal MGC-24 PF05283.6 GAK62620.1 - 0.001 18.8 13.3 0.001 18.8 9.2 2.4 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) TMEM190 PF15431.1 GAK62620.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 HAMP PF00672.20 GAK62620.1 - 0.06 13.5 0.7 0.34 11.1 0.1 2.3 2 0 0 2 2 2 0 HAMP domain Beta-APP PF03494.8 GAK62620.1 - 0.19 11.2 2.7 0.33 10.4 1.9 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Herpes_BLLF1 PF05109.8 GAK62620.1 - 4.8 5.0 29.7 0.0055 14.7 10.4 2.1 2 0 0 2 2 2 0 Herpes virus major outer envelope glycoprotein (BLLF1) Sugar_tr PF00083.19 GAK62621.1 - 4.1e-118 394.8 27.4 4.8e-118 394.6 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK62621.1 - 2.6e-25 88.9 34.9 1.1e-21 76.9 6.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rhodanese PF00581.15 GAK62622.1 - 9.8e-17 61.3 0.0 1.4e-09 38.2 0.0 3.1 2 1 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.1 GAK62622.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 ThiC-associated domain MFS_1 PF07690.11 GAK62623.1 - 2.7e-26 92.1 27.3 2.7e-26 92.1 18.9 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAK62623.1 - 0.0017 18.3 8.2 0.046 13.7 0.8 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) DUF3452 PF11934.3 GAK62623.1 - 6.2 6.1 5.6 5.7 6.2 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) HIG_1_N PF04588.8 GAK62625.1 - 3e-19 68.5 0.1 4.2e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Aa_trans PF01490.13 GAK62626.1 - 5.6e-53 179.8 39.3 6.3e-53 179.7 27.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EI24 PF07264.6 GAK62627.1 - 9.7e-31 106.8 8.4 1.4e-30 106.4 5.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Yeast-kill-tox PF09207.6 GAK62628.1 - 0.07 13.5 2.7 2 8.9 0.2 2.8 3 0 0 3 3 3 0 Yeast killer toxin DHquinase_II PF01220.14 GAK62629.1 - 2.1e-61 205.3 0.0 2.4e-61 205.1 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II ALO PF04030.9 GAK62630.1 - 1.5e-70 237.8 4.3 6e-62 209.5 0.7 2.7 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 GAK62630.1 - 8.4e-19 67.4 0.1 1.9e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Shisa PF13908.1 GAK62631.1 - 0.002 18.3 0.2 0.0029 17.7 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 GAK62631.1 - 0.0047 17.2 0.0 0.0065 16.8 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.3 GAK62631.1 - 0.0098 16.4 17.4 0.034 14.7 11.9 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red ASFV_J13L PF05568.6 GAK62631.1 - 0.019 14.5 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein NfeD PF01957.13 GAK62631.1 - 0.021 14.9 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4179 PF13786.1 GAK62631.1 - 0.052 13.7 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Glyco_transf_56 PF07429.6 GAK62631.1 - 0.056 12.3 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Sec66 PF09802.4 GAK62631.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF347 PF03988.7 GAK62631.1 - 0.1 12.5 0.7 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) MacB_PCD PF12704.2 GAK62631.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain SKG6 PF08693.5 GAK62631.1 - 0.21 10.9 3.6 0.3 10.4 2.5 1.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SUR7 PF06687.7 GAK62632.1 - 8.6e-09 35.2 8.1 2.1e-08 33.9 5.6 1.6 1 1 0 1 1 1 1 SUR7/PalI family DUF3767 PF12597.3 GAK62633.1 - 3e-25 88.1 0.1 3.6e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) TPR_11 PF13414.1 GAK62634.1 - 2.1e-23 81.7 8.8 1.9e-10 40.2 0.3 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 GAK62634.1 - 2.7e-18 64.7 6.4 2.7e-06 26.7 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAK62634.1 - 3.4e-17 60.9 7.7 7.2e-07 28.6 0.1 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAK62634.1 - 3.5e-13 49.8 4.7 2.4e-07 31.2 0.2 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAK62634.1 - 5.3e-13 48.7 8.1 1.2e-05 25.0 0.0 3.4 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAK62634.1 - 3e-12 45.7 6.3 0.0055 16.7 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAK62634.1 - 1.2e-11 44.7 5.4 8.6e-06 26.0 0.3 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAK62634.1 - 2e-11 43.4 7.9 0.00047 20.5 0.1 4.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAK62634.1 - 3.9e-09 35.6 5.4 0.085 12.6 0.0 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAK62634.1 - 4.6e-09 35.4 5.0 0.025 14.3 0.0 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAK62634.1 - 5.5e-06 26.4 2.2 0.032 14.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAK62634.1 - 6.2e-05 22.2 1.7 0.00012 21.2 1.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAK62634.1 - 0.00013 21.7 3.2 0.0048 16.7 0.2 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAK62634.1 - 0.00044 20.3 6.0 0.044 13.9 0.3 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 GAK62634.1 - 0.012 15.7 6.2 0.041 13.9 0.4 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAK62634.1 - 0.038 13.9 13.5 2 8.4 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF2034 PF10356.4 GAK62635.1 - 6.3e-20 71.1 1.6 6.8e-13 48.1 1.2 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 GAK62635.1 - 7.3e-08 32.2 0.0 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease Oxidored_FMN PF00724.15 GAK62636.1 - 1.7e-54 185.1 0.0 9.5e-54 182.6 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family bPH_6 PF10756.4 GAK62636.1 - 0.042 13.7 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial PH domain ADH_zinc_N PF00107.21 GAK62637.1 - 5.7e-34 116.4 0.7 8.1e-34 115.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK62637.1 - 1.2e-10 42.3 0.0 2.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK62637.1 - 2.6e-06 27.1 0.0 6.7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAK62637.1 - 0.0018 17.8 0.2 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Acetyltransf_8 PF13523.1 GAK62638.1 - 3.9e-34 117.7 0.1 5.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 GAK62639.1 - 0.0034 17.2 7.0 0.0062 16.4 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDH_alpha PF03313.10 GAK62640.1 - 8.9e-102 339.9 0.4 1.5e-101 339.1 0.3 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 GAK62640.1 - 1.1e-52 178.2 0.1 3.1e-52 176.7 0.0 1.8 2 0 0 2 2 2 1 Serine dehydratase beta chain zf-rbx1 PF12678.2 GAK62641.1 - 1.2e-07 31.6 1.6 2.1e-07 30.9 1.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAK62641.1 - 5.2e-05 22.9 5.7 5.2e-05 22.9 3.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAK62641.1 - 6.6e-05 22.4 1.0 0.00016 21.2 0.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK62641.1 - 0.012 15.3 3.3 0.026 14.2 2.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAK62641.1 - 0.16 12.0 6.3 0.091 12.8 1.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAK62641.1 - 0.26 11.1 3.8 0.38 10.6 1.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 GAK62641.1 - 0.96 9.1 6.7 4.7 6.9 4.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DnaJ PF00226.26 GAK62642.1 - 4.1e-16 58.4 1.8 8.4e-16 57.4 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2924 PF11149.3 GAK62642.1 - 0.085 12.8 4.1 0.17 11.9 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) DUF2839 PF10999.3 GAK62642.1 - 0.14 12.2 2.6 3.1 7.8 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) LcrG PF07216.7 GAK62642.1 - 2 8.5 6.3 1.8 8.6 2.0 2.4 2 1 0 2 2 2 0 LcrG protein PolC_DP2 PF03833.8 GAK62643.1 - 0.076 10.6 0.4 0.1 10.2 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Transaldolase PF00923.14 GAK62644.1 - 2.4e-45 154.8 0.1 3.7e-45 154.2 0.1 1.2 1 0 0 1 1 1 1 Transaldolase Pyr_redox_2 PF07992.9 GAK62645.1 - 1.7e-26 93.3 10.1 2e-24 86.6 7.0 3.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK62645.1 - 9e-14 52.0 0.3 2.6e-08 34.1 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 GAK62645.1 - 1.6e-13 49.9 0.0 4.5e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 GAK62645.1 - 4.3e-13 49.4 9.0 4.4e-11 43.0 0.8 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAK62645.1 - 2.3e-05 23.5 0.8 0.12 11.3 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 GAK62645.1 - 5.3e-05 23.4 0.0 0.00089 19.5 0.0 2.5 2 0 0 2 2 2 1 Reductase C-terminal GIDA PF01134.17 GAK62645.1 - 0.00072 18.5 1.3 0.02 13.7 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAK62645.1 - 0.0019 18.0 2.9 0.02 14.6 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 GAK62645.1 - 0.0099 16.1 6.2 0.085 13.1 0.3 2.7 3 0 0 3 3 2 1 Putative NAD(P)-binding Rieske_2 PF13806.1 GAK62645.1 - 0.012 15.2 0.0 0.066 12.9 0.0 2.3 2 0 0 2 2 2 0 Rieske-like [2Fe-2S] domain CPSase_L_chain PF00289.17 GAK62645.1 - 0.12 12.4 1.1 0.69 10.0 0.1 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_binding_2 PF00890.19 GAK62645.1 - 0.33 9.7 9.0 4.2 6.0 0.5 3.5 3 1 1 4 4 4 0 FAD binding domain TrkA_N PF02254.13 GAK62645.1 - 0.42 10.6 3.8 3.3 7.7 0.3 2.7 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_8 PF13450.1 GAK62645.1 - 0.43 10.6 2.4 5.1 7.2 0.2 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAK62645.1 - 0.56 8.6 0.0 0.56 8.6 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Sdh5 PF03937.11 GAK62647.1 - 7.5e-25 86.4 0.3 1.1e-24 85.9 0.2 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase MFS_1 PF07690.11 GAK62648.1 - 3.1e-38 131.3 47.7 3.1e-38 131.3 33.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK62648.1 - 1.7e-08 33.4 18.8 2.7e-08 32.8 8.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 GAK62648.1 - 0.06 11.3 1.6 0.4 8.6 0.9 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Na_trans_assoc PF06512.8 GAK62648.1 - 0.23 11.4 2.1 0.31 10.9 1.4 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4381 PF14316.1 GAK62648.1 - 1 9.4 0.0 1 9.4 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4381) Fungal_trans PF04082.13 GAK62649.1 - 1.1e-06 27.7 3.1 8.5e-05 21.5 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK62649.1 - 8.6e-06 25.5 7.5 1.5e-05 24.7 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF793 PF05633.6 GAK62649.1 - 0.043 12.5 0.9 0.087 11.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF793) PQ-loop PF04193.9 GAK62651.1 - 1.9e-18 65.7 23.1 2.7e-10 39.6 4.4 3.6 4 0 0 4 4 4 2 PQ loop repeat SKG6 PF08693.5 GAK62651.1 - 0.085 12.1 1.1 0.28 10.5 0.8 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 GAK62651.1 - 0.15 11.7 1.1 16 5.2 0.1 2.5 2 0 0 2 2 2 0 Syndecan domain Pro_dh PF01619.13 GAK62652.1 - 2e-35 122.3 0.0 3.1e-17 62.5 0.0 3.9 2 1 0 2 2 2 2 Proline dehydrogenase DUF706 PF05153.10 GAK62654.1 - 3.3e-122 406.6 0.7 4e-122 406.3 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 GAK62654.1 - 0.0029 17.6 0.4 0.99 9.4 0.0 2.8 3 0 0 3 3 3 2 HD domain zf-DNL PF05180.7 GAK62655.1 - 1.9e-29 101.1 0.3 2.8e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 DNL zinc finger DUF4097 PF13349.1 GAK62655.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Amidase PF01425.16 GAK62656.1 - 3.4e-89 299.7 0.0 4.7e-89 299.2 0.0 1.2 1 0 0 1 1 1 1 Amidase Seryl_tRNA_N PF02403.17 GAK62656.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Arch_ATPase PF01637.13 GAK62657.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 GAK62657.1 - 0.0019 18.2 0.2 0.016 15.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Nucleoplasmin PF03066.10 GAK62657.1 - 0.13 11.8 1.2 0.25 10.8 0.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 GAK62657.1 - 3.1 5.5 6.2 16 3.1 2.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 GAK62657.1 - 6.3 7.1 9.4 2 8.8 3.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.6 GAK62657.1 - 6.5 5.3 5.4 1.1 7.8 0.3 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.7 GAK62657.1 - 9.1 4.0 6.2 12 3.6 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family PUA PF01472.15 GAK62658.1 - 3.8e-20 71.3 0.2 5.5e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 PUA domain SQS_PSY PF00494.14 GAK62659.1 - 5.7e-53 179.9 0.3 9.1e-53 179.2 0.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase PTPLA PF04387.9 GAK62660.1 - 3.1e-53 179.5 6.5 5.5e-53 178.7 4.5 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA HlyIII PF03006.15 GAK62661.1 - 3.6e-50 170.4 15.4 4.7e-50 170.0 10.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related GAS PF13851.1 GAK62661.1 - 0.21 10.7 0.4 0.33 10.1 0.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Apolipoprotein PF01442.13 GAK62661.1 - 1.3 8.4 8.0 0.6 9.5 2.3 2.3 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain p450 PF00067.17 GAK62662.1 - 3.1e-82 276.5 0.0 3.8e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GDPD PF03009.12 GAK62663.1 - 7.5e-32 110.8 0.0 1.2e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Polysacc_synt_C PF14667.1 GAK62663.1 - 0.094 12.5 0.7 0.16 11.7 0.5 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain AFG1_ATPase PF03969.11 GAK62665.1 - 1.6e-88 296.9 0.0 5.8e-86 288.5 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 GAK62665.1 - 1.3e-06 28.5 0.0 9.8e-06 25.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAK62665.1 - 2.5e-06 27.5 0.2 3.8e-05 23.7 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 GAK62665.1 - 0.0012 19.0 0.1 0.011 15.9 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAK62665.1 - 0.016 14.9 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 GAK62665.1 - 0.054 13.6 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF2638 PF10937.3 GAK62665.1 - 0.93 10.5 9.3 0.19 12.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) DUF3446 PF11928.3 GAK62665.1 - 4.9 7.4 25.9 12 6.2 5.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Glyoxalase_2 PF12681.2 GAK62666.1 - 8.5e-20 71.3 0.0 2.3e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAK62666.1 - 0.00058 19.8 0.0 0.008 16.1 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.11 GAK62667.1 - 2.3e-31 108.8 29.1 6.6e-31 107.2 20.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEM237 PF15383.1 GAK62667.1 - 2.1 7.4 6.1 0.48 9.5 0.1 2.5 2 1 2 4 4 4 0 Transmembrane protein 237 Abhydrolase_6 PF12697.2 GAK62668.1 - 2.4e-24 86.4 4.0 4.5e-24 85.5 2.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK62668.1 - 7.8e-11 41.9 0.1 1.5e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK62668.1 - 1.4e-05 24.7 0.2 0.00015 21.4 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAK62668.1 - 2.1e-05 24.8 0.1 3.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 GAK62668.1 - 0.00011 22.0 0.1 0.0003 20.5 0.0 1.7 1 1 1 2 2 2 1 Putative lysophospholipase PGAP1 PF07819.8 GAK62668.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 GAK62668.1 - 0.0024 17.4 0.1 0.0049 16.4 0.1 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF900 PF05990.7 GAK62668.1 - 0.004 16.5 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.2 GAK62668.1 - 0.043 12.6 0.1 0.067 12.0 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 GAK62669.1 - 8.6e-35 120.2 0.1 1.2e-34 119.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAK62669.1 - 0.00049 19.4 0.1 0.0015 17.8 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAK62669.1 - 0.0051 16.5 0.0 0.012 15.4 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAK62669.1 - 0.054 12.9 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 GAK62669.1 - 0.085 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Nucleoplasmin PF03066.10 GAK62669.1 - 0.2 11.1 1.7 0.32 10.5 1.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sugar_tr PF00083.19 GAK62670.1 - 8.1e-51 173.0 19.9 1.1e-50 172.5 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK62670.1 - 4.1e-27 94.8 29.8 1.2e-15 57.1 6.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPMT PF05724.6 GAK62673.1 - 3.1e-29 101.9 0.0 1.3e-26 93.3 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 GAK62673.1 - 1.7e-06 28.0 0.1 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK62673.1 - 5.1e-06 26.8 0.0 7.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK62673.1 - 6.8e-06 26.6 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK62673.1 - 7.8e-06 26.1 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK62673.1 - 1.5e-05 24.6 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK62673.1 - 0.00023 21.6 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK62673.1 - 0.00056 19.6 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK62673.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_92 PF07971.7 GAK62674.1 - 4e-113 378.7 0.0 6e-113 378.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF2540 PF10802.3 GAK62675.1 - 0.0024 17.5 0.3 0.0041 16.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2540) DUF4554 PF15091.1 GAK62677.1 - 0.2 10.3 4.1 0.41 9.3 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Oxidored_FMN PF00724.15 GAK62678.1 - 3.3e-49 167.6 0.0 7.1e-49 166.6 0.0 1.5 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_1 PF00583.19 GAK62679.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK62679.1 - 0.0089 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAK62679.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK62679.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein adh_short PF00106.20 GAK62680.1 - 1.4e-30 106.4 1.9 2e-30 105.8 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK62680.1 - 2.8e-14 53.1 1.7 4.6e-14 52.4 1.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK62680.1 - 5.9e-08 32.7 0.0 8.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAK62680.1 - 0.0017 17.7 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAK62680.1 - 0.045 13.5 0.0 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAO PF01266.19 GAK62680.1 - 0.047 12.5 1.0 0.07 12.0 0.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glutaredoxin PF00462.19 GAK62680.1 - 0.06 13.3 0.0 1.4 8.9 0.0 2.7 2 1 1 3 3 3 0 Glutaredoxin 2-Hacid_dh_C PF02826.14 GAK62680.1 - 0.061 12.4 0.2 0.17 11.0 0.1 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAK62680.1 - 0.072 11.9 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Tub_2 PF04525.7 GAK62682.1 - 2.1e-19 69.6 0.0 2.6e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 DUF1295 PF06966.7 GAK62683.1 - 1.7e-51 174.7 0.2 2.7e-51 174.1 0.1 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 GAK62683.1 - 4.9e-06 26.6 0.0 2.1e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 GAK62683.1 - 0.00016 21.4 0.1 0.00035 20.3 0.0 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 GAK62683.1 - 0.00033 20.7 2.2 0.00044 20.3 0.0 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF3382 PF11862.3 GAK62683.1 - 0.076 12.9 0.5 0.4 10.6 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) Choline_transpo PF04515.7 GAK62684.1 - 6.1e-88 294.7 28.6 6.1e-88 294.7 19.8 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Nse5 PF08691.5 GAK62684.1 - 0.23 9.9 0.0 0.36 9.3 0.0 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 AMP-binding PF00501.23 GAK62685.1 - 1.2e-66 224.8 0.2 2.8e-65 220.3 0.1 2.6 1 1 0 1 1 1 1 AMP-binding enzyme YukC PF10140.4 GAK62686.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Fungal_trans_2 PF11951.3 GAK62687.1 - 5.9e-40 137.0 0.2 2.9e-39 134.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK62687.1 - 2.7e-05 23.9 12.7 5.1e-05 23.0 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.26 GAK62688.1 - 4e-21 74.5 4.1 6.7e-21 73.7 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAK62688.1 - 2.7e-16 59.3 13.6 4.2e-16 58.7 9.5 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 GAK62688.1 - 4.8e-16 58.4 0.0 3.5e-14 52.4 0.0 2.6 2 1 0 2 2 2 1 DnaJ C terminal domain A2L_zn_ribbon PF08792.5 GAK62688.1 - 0.045 13.2 0.1 0.045 13.2 0.1 3.7 3 1 1 4 4 4 0 A2L zinc ribbon domain Indigoidine_A PF04227.7 GAK62689.1 - 7.7e-115 383.1 0.3 1.1e-114 382.5 0.2 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 GAK62689.1 - 1e-21 77.3 2.6 1.6e-20 73.4 1.8 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase AP_endonuc_2 PF01261.19 GAK62690.1 - 8e-16 57.9 0.0 3.7e-10 39.4 0.0 2.9 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel FKBP_C PF00254.23 GAK62691.1 - 1.8e-29 101.5 0.1 9.4e-29 99.2 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Abhydrolase_6 PF12697.2 GAK62693.1 - 1.8e-11 44.3 1.3 3e-11 43.6 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK62693.1 - 6.1e-09 35.7 0.0 1.2e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK62693.1 - 6e-08 32.1 0.1 7.7e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAK62693.1 - 8.4e-07 28.7 0.3 0.00021 20.9 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.5 GAK62693.1 - 4.8e-06 25.6 0.0 1.6e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.3 GAK62693.1 - 0.022 14.6 1.1 0.067 13.0 0.8 1.8 2 0 0 2 2 2 0 Putative lysophospholipase DUF915 PF06028.6 GAK62693.1 - 0.06 12.4 0.0 0.67 9.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydro_lipase PF04083.11 GAK62693.1 - 0.084 12.2 0.3 0.45 9.9 0.2 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region CoA_transf_3 PF02515.12 GAK62694.1 - 1.3e-33 115.8 0.0 5.5e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III MFS_1 PF07690.11 GAK62695.1 - 1.7e-39 135.5 41.5 1.7e-39 135.5 28.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 GAK62695.1 - 0.0029 16.9 5.4 0.025 13.8 0.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1129) Milton PF12448.3 GAK62696.1 - 0.00065 19.9 0.2 0.00091 19.4 0.1 1.3 1 1 0 1 1 1 1 Kinesin associated protein DUF4315 PF14193.1 GAK62696.1 - 0.17 11.8 0.9 0.24 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Rrp15p PF07890.7 GAK62696.1 - 1.4 9.0 8.1 3.4 7.7 5.6 1.5 1 1 0 1 1 1 0 Rrp15p Carboxyl_trans PF01039.17 GAK62697.1 - 7e-108 361.1 0.0 8.5e-108 360.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Myb_DNA-binding PF00249.26 GAK62698.1 - 1.3e-26 92.4 4.2 7.3e-12 45.1 0.0 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAK62698.1 - 1.4e-26 92.3 1.4 3e-10 40.0 0.0 4.2 1 1 3 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 GAK62698.1 - 0.00031 20.5 0.4 0.42 10.5 0.0 2.6 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 GAK62698.1 - 0.037 14.1 5.9 0.45 10.6 0.1 3.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 GAK62698.1 - 0.15 12.2 3.8 11 6.3 0.0 3.1 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 GAK62698.1 - 0.16 11.9 1.0 1.8 8.5 0.0 2.9 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF2217 PF10265.4 GAK62698.1 - 0.16 10.7 4.9 0.25 10.0 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DEAD PF00270.24 GAK62699.1 - 3.2e-20 72.2 0.0 1.1e-19 70.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK62699.1 - 0.00011 22.0 0.0 0.00047 19.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 GAK62699.1 - 0.27 10.2 0.0 0.47 9.4 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fe-S_biosyn PF01521.15 GAK62700.1 - 9.3e-17 60.9 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis AAA PF00004.24 GAK62701.1 - 6.4e-44 149.3 0.0 1.3e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 GAK62701.1 - 1.4e-07 31.5 0.0 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAK62701.1 - 2e-06 27.9 0.2 1.4e-05 25.1 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 GAK62701.1 - 2.4e-06 27.2 0.0 1.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAK62701.1 - 3.3e-06 27.2 0.1 0.00029 20.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK62701.1 - 5e-05 22.9 0.0 0.00016 21.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAK62701.1 - 0.00011 22.9 0.0 0.00028 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAK62701.1 - 0.00014 21.0 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAK62701.1 - 0.00037 19.9 0.0 0.00078 18.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 GAK62701.1 - 0.0012 17.6 0.0 0.0024 16.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 GAK62701.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAK62701.1 - 0.0024 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAK62701.1 - 0.003 16.6 0.0 0.0062 15.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 GAK62701.1 - 0.0032 17.4 0.2 0.0074 16.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain PhoH PF02562.11 GAK62701.1 - 0.0038 16.4 0.0 0.073 12.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF2072 PF09845.4 GAK62701.1 - 0.0061 16.4 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_3 PF07726.6 GAK62701.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 GAK62701.1 - 0.0076 15.4 0.1 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAK62701.1 - 0.0086 16.3 0.0 0.027 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain KaiC PF06745.8 GAK62701.1 - 0.019 14.1 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 GAK62701.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAK62701.1 - 0.024 14.0 0.1 0.09 12.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 GAK62701.1 - 0.024 14.1 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 GAK62701.1 - 0.029 13.2 0.0 0.056 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 GAK62701.1 - 0.04 14.0 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 GAK62701.1 - 0.046 12.5 0.0 0.092 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 GAK62701.1 - 0.061 13.3 0.0 0.2 11.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 GAK62701.1 - 0.064 12.9 0.0 0.6 9.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.17 GAK62701.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mak10 PF04112.8 GAK62703.1 - 3.1e-50 169.6 0.0 5.4e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Alpha-L-AF_C PF06964.7 GAK62704.1 - 2.1e-38 131.8 0.1 3.6e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 GAK62704.1 - 1.6e-05 24.9 0.4 4.1e-05 23.6 0.3 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain Ferric_reduct PF01794.14 GAK62705.1 - 5e-17 62.1 15.3 5e-17 62.1 10.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAK62705.1 - 6.7e-12 45.5 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAK62705.1 - 3.9e-07 29.8 0.0 8.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain MFS_1 PF07690.11 GAK62706.1 - 3.5e-13 48.9 34.2 4.1e-09 35.6 2.9 4.2 2 1 1 3 3 3 2 Major Facilitator Superfamily NAD_binding_6 PF08030.7 GAK62706.1 - 4.8e-08 33.0 0.0 1.6e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAK62706.1 - 1.7e-06 27.8 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 GAK62706.1 - 6.8e-06 26.1 7.2 6.8e-06 26.1 5.0 3.1 4 0 0 4 4 4 1 Ferric reductase like transmembrane component Fungal_trans PF04082.13 GAK62707.1 - 3.6e-10 39.1 0.2 5.9e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK62707.1 - 1.3e-06 28.2 9.7 2.2e-06 27.4 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAK62708.1 - 4e-38 131.0 46.7 4e-38 131.0 32.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAK62708.1 - 1e-11 43.7 21.4 2.2e-11 42.6 14.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Complex1_LYR PF05347.10 GAK62709.1 - 1.8e-09 37.2 1.3 2.9e-09 36.5 0.9 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAK62709.1 - 5.8e-09 36.0 1.2 9.2e-09 35.3 0.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF1155 PF06633.6 GAK62710.1 - 0.099 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) DUF2417 PF10329.4 GAK62710.1 - 0.64 9.3 3.8 0.18 11.1 0.7 1.5 2 0 0 2 2 2 0 Region of unknown function (DUF2417) SH3_9 PF14604.1 GAK62711.1 - 9.4e-21 73.1 0.1 4.4e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAK62711.1 - 9.5e-18 63.3 0.0 4.7e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAK62711.1 - 4.4e-16 58.1 0.0 2.5e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 GAK62711.1 - 1.5e-14 53.8 0.1 1.4e-13 50.7 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 GAK62711.1 - 7.8e-12 44.7 3.6 1.6e-11 43.7 2.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 GAK62711.1 - 0.023 14.8 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain FHA PF00498.21 GAK62712.1 - 1.2e-14 54.1 0.1 2.7e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 FHA domain Fer2_3 PF13085.1 GAK62713.1 - 2.2e-31 107.9 0.0 3.6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 GAK62713.1 - 3.8e-10 39.9 7.2 3.8e-10 39.9 5.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 GAK62713.1 - 1.2e-08 34.8 5.5 1.2e-08 34.8 3.8 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAK62713.1 - 9.1e-05 22.6 3.0 0.057 13.6 0.2 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 GAK62713.1 - 0.00027 21.2 3.6 0.00027 21.2 2.5 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAK62713.1 - 0.00036 20.2 4.8 0.00036 20.2 3.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 GAK62713.1 - 0.00063 20.0 4.9 0.00063 20.0 3.4 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 GAK62713.1 - 0.0066 16.1 0.5 0.0066 16.1 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 GAK62713.1 - 0.24 11.9 4.7 1.1 9.8 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Metallophos_C PF14008.1 GAK62714.1 - 4.8e-19 68.1 0.4 1.1e-18 67.0 0.2 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 GAK62714.1 - 1.1e-18 67.3 0.4 1.8e-18 66.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAK62714.1 - 3.3e-06 27.0 0.0 6.7e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 GAK62714.1 - 1.8e-05 23.5 0.0 3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase CAP59_mtransfer PF11735.3 GAK62715.1 - 7.2e-77 257.8 0.2 9.9e-77 257.4 0.1 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_4 PF13704.1 GAK62715.1 - 0.024 14.9 0.1 0.058 13.7 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 MARVEL PF01284.18 GAK62715.1 - 0.062 13.1 5.7 0.14 11.9 3.9 1.5 1 0 0 1 1 1 0 Membrane-associating domain Scs3p PF10261.4 GAK62715.1 - 1.6 7.7 7.3 0.055 12.5 0.7 1.7 2 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM CMAS PF02353.15 GAK62716.1 - 3.5e-65 219.8 0.0 3.7e-53 180.3 0.0 2.9 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 GAK62716.1 - 1.2e-09 38.7 0.0 3.7e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK62716.1 - 6.2e-09 35.7 0.0 1.5e-08 34.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK62716.1 - 4.9e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK62716.1 - 3.2e-06 26.8 0.0 7.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK62716.1 - 0.00036 20.5 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK62716.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 GAK62716.1 - 0.056 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 GAK62716.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 GAK62716.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Phyto_Pns9_10 PF05878.6 GAK62717.1 - 0.16 10.9 0.2 0.3 10.0 0.2 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 PCI PF01399.22 GAK62719.1 - 1.9e-08 34.5 0.0 4.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain FimP PF09766.4 GAK62719.1 - 0.031 13.3 5.1 0.05 12.6 3.5 1.3 1 0 0 1 1 1 0 Fms-interacting protein TOBE_3 PF12857.2 GAK62720.1 - 0.08 12.8 0.2 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 TOBE-like domain SKG6 PF08693.5 GAK62721.1 - 0.02 14.2 0.2 0.052 12.8 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 GAK62721.1 - 0.028 14.0 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1049 PF06305.6 GAK62721.1 - 0.059 12.8 0.1 0.059 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1191 PF06697.7 GAK62721.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 GAK62721.1 - 0.15 10.3 0.0 0.25 9.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Tmemb_14 PF03647.8 GAK62722.1 - 5.9e-21 74.6 5.2 8.4e-21 74.1 3.6 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3422 PF11902.3 GAK62723.1 - 0.0081 15.0 5.5 0.0081 15.0 3.8 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3422) MtrG PF04210.8 GAK62723.1 - 0.063 12.9 0.7 1.4 8.6 0.1 2.9 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G L27 PF02828.11 GAK62723.1 - 0.066 12.9 0.6 0.35 10.5 0.0 2.4 2 0 0 2 2 2 0 L27 domain DUF3461 PF11944.3 GAK62723.1 - 0.14 12.0 7.2 0.23 11.2 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) NPV_P10 PF05531.7 GAK62723.1 - 0.17 12.1 10.3 5.8 7.2 2.5 4.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 GAK62723.1 - 0.29 8.5 4.6 0.51 7.8 3.2 1.4 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.1 GAK62723.1 - 1.6 7.6 34.1 1.1 8.1 4.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 GAK62723.1 - 1.7 8.5 5.1 63 3.5 0.2 3.9 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) UPF0184 PF03670.8 GAK62723.1 - 6.3 7.0 11.7 41 4.4 3.6 4.6 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) HALZ PF02183.13 GAK62723.1 - 7.8 6.3 13.8 3 7.6 0.2 4.8 4 1 1 5 5 5 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 GAK62723.1 - 7.8 6.3 10.1 37 4.1 2.6 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_2_N PF02837.13 GAK62724.1 - 6.1e-24 84.4 1.1 1e-23 83.7 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAK62724.1 - 2e-16 59.7 0.0 4.5e-16 58.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 GAK62724.1 - 3.1e-07 30.8 0.0 6.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 adh_short_C2 PF13561.1 GAK62725.1 - 1.6e-24 87.0 0.1 2.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK62725.1 - 3.4e-23 82.4 0.7 6.1e-23 81.5 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK62725.1 - 1.6e-10 40.9 0.3 3.1e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 KR domain Longin PF13774.1 GAK62726.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Regulated-SNARE-like domain Fer2 PF00111.22 GAK62727.1 - 2.1e-11 43.3 0.2 3e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ProRS-C_1 PF09180.6 GAK62728.1 - 2.4e-23 81.7 1.7 5.8e-23 80.6 1.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 GAK62728.1 - 1.5e-22 80.0 0.1 5.9e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAK62728.1 - 2.7e-20 72.0 0.0 8e-20 70.5 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 GAK62728.1 - 2.3e-17 62.9 0.4 4.7e-17 61.9 0.3 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain AAA_33 PF13671.1 GAK62728.1 - 0.11 12.3 0.2 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.18 GAK62729.1 - 1e-38 129.4 47.1 1.9e-08 33.8 1.0 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 GAK62729.1 - 8.9e-07 28.5 29.6 0.63 9.8 0.1 6.1 4 2 2 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.1 GAK62729.1 - 2.8e-06 26.6 29.4 0.018 14.5 0.3 6.2 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 GAK62729.1 - 0.00016 21.2 37.8 0.28 10.8 0.3 6.0 6 0 0 6 6 6 5 Zinc knuckle HNH_3 PF13392.1 GAK62730.1 - 0.034 13.5 0.2 0.034 13.5 0.1 1.7 2 0 0 2 2 2 0 HNH endonuclease SKN1 PF03935.10 GAK62731.1 - 2.3e-204 679.2 1.3 2.8e-204 678.9 0.9 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) THOC7 PF05615.8 GAK62732.1 - 8.3e-23 81.1 9.2 8.3e-23 81.1 6.4 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 DUF2853 PF11015.3 GAK62732.1 - 0.0024 18.2 1.8 0.029 14.8 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2853) CENP-F_leu_zip PF10473.4 GAK62732.1 - 0.0025 17.6 8.5 0.0025 17.6 5.9 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 GAK62732.1 - 0.0029 17.3 4.5 0.015 15.0 1.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Mnd1 PF03962.10 GAK62732.1 - 0.0071 16.0 5.8 0.0071 16.0 4.0 1.6 1 1 1 2 2 2 1 Mnd1 family Arfaptin PF06456.8 GAK62732.1 - 0.013 14.8 1.4 0.013 14.8 1.0 1.9 2 1 0 2 2 2 0 Arfaptin-like domain FUSC PF04632.7 GAK62732.1 - 0.32 9.3 9.1 0.53 8.6 6.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2408 PF10303.4 GAK62732.1 - 0.39 10.8 6.0 4 7.5 4.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) APG6 PF04111.7 GAK62732.1 - 0.45 9.5 8.9 0.68 8.9 5.3 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4559 PF15112.1 GAK62732.1 - 0.57 9.3 3.7 0.82 8.7 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Snapin_Pallidin PF14712.1 GAK62732.1 - 0.85 9.9 6.7 0.62 10.4 0.4 2.5 1 1 2 3 3 3 0 Snapin/Pallidin Kinetocho_Slk19 PF12709.2 GAK62732.1 - 1.3 9.1 6.6 1.7 8.7 1.1 2.8 2 1 1 3 3 3 0 Central kinetochore-associated Fzo_mitofusin PF04799.8 GAK62732.1 - 1.8 7.9 6.1 1.1 8.6 1.3 2.0 1 1 0 2 2 2 0 fzo-like conserved region DivIC PF04977.10 GAK62732.1 - 3.3 7.2 9.1 3 7.3 2.0 2.4 1 1 1 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.3 GAK62732.1 - 4.5 7.0 13.3 2.8 7.7 3.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BID PF06393.6 GAK62732.1 - 5.1 6.4 8.2 0.69 9.2 2.4 2.0 2 1 0 2 2 2 0 BH3 interacting domain (BID) Spc24 PF08286.6 GAK62732.1 - 5.2 6.7 6.5 4.8 6.9 1.3 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 GAK62732.1 - 8.4 6.9 14.5 16 6.0 1.2 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 GAK62732.1 - 9.1 5.7 10.2 7.4 6.0 2.4 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CTP_transf_1 PF01148.15 GAK62733.1 - 1 8.9 4.8 1.3 8.5 3.3 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family UCH PF00443.24 GAK62734.1 - 2.7e-40 138.1 0.0 1.1e-35 123.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK62734.1 - 0.032 13.6 0.0 22 4.3 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L14e PF01929.12 GAK62735.1 - 1.8e-28 98.6 0.6 2.3e-28 98.3 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 GAK62735.1 - 0.00017 21.1 0.4 0.00028 20.4 0.3 1.3 1 0 0 1 1 1 1 KOW motif Ribosomal_L44 PF00935.14 GAK62736.1 - 1.9e-33 114.3 9.5 2.9e-33 113.6 6.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DnaJ PF00226.26 GAK62737.1 - 1.6e-19 69.3 0.1 1.6e-19 69.3 0.0 2.6 2 1 0 2 2 2 1 DnaJ domain tRNA-synt_2b PF00587.20 GAK62738.1 - 1e-35 122.8 0.7 1.5e-35 122.3 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 GAK62738.1 - 9.5e-21 73.8 9.7 9.5e-21 73.8 6.7 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain NuA4 PF09340.5 GAK62738.1 - 0.0017 17.9 0.1 0.005 16.4 0.1 1.8 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 tRNA-synt_His PF13393.1 GAK62738.1 - 0.032 13.3 1.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase PEP-utilisers_N PF05524.8 GAK62738.1 - 0.042 13.6 0.5 0.091 12.5 0.4 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Mod_r PF07200.8 GAK62738.1 - 0.073 12.9 4.6 0.18 11.7 3.2 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YPEB PF14620.1 GAK62738.1 - 0.076 12.0 4.9 0.11 11.5 2.6 1.7 2 0 0 2 2 2 0 YpeB sporulation Wbp11 PF09429.5 GAK62738.1 - 0.25 11.3 9.5 0.98 9.4 3.5 2.6 2 1 0 2 2 2 0 WW domain binding protein 11 IncA PF04156.9 GAK62738.1 - 3.2 7.3 5.4 1.3 8.6 1.4 1.9 2 0 0 2 2 2 0 IncA protein Glyco_hydro_8 PF01270.12 GAK62739.1 - 1e-38 132.9 0.0 1.2e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 DUF481 PF04338.7 GAK62739.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF481 Ribosomal_S8 PF00410.14 GAK62740.1 - 5.4e-24 84.4 0.1 7.3e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 GAK62741.1 - 8.2e-57 190.2 0.0 4.6e-56 187.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal S17 TFIIA PF03153.8 GAK62741.1 - 0.82 9.5 3.3 1 9.2 2.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_A_exo1 PF01612.15 GAK62742.1 - 5.9e-18 64.9 0.0 1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Prefoldin_2 PF01920.15 GAK62743.1 - 9.4e-23 79.9 14.4 1.1e-22 79.7 10.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 GAK62743.1 - 0.0023 17.6 7.1 0.003 17.2 4.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Snf7 PF03357.16 GAK62743.1 - 0.0026 17.1 3.9 0.0026 17.1 2.7 2.0 2 0 0 2 2 2 1 Snf7 Nckap1 PF09735.4 GAK62743.1 - 0.0042 14.6 1.4 0.0044 14.5 1.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein IncA PF04156.9 GAK62743.1 - 0.019 14.5 9.8 0.025 14.1 6.8 1.1 1 0 0 1 1 1 0 IncA protein ALIX_LYPXL_bnd PF13949.1 GAK62743.1 - 0.024 13.6 5.3 0.028 13.3 3.6 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4349 PF14257.1 GAK62743.1 - 0.024 13.8 6.0 0.029 13.5 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) BTAD PF03704.12 GAK62743.1 - 0.025 14.8 0.3 0.053 13.8 0.2 1.5 1 0 0 1 1 1 0 Bacterial transcriptional activator domain STAT_alpha PF01017.15 GAK62743.1 - 0.031 13.9 5.3 0.14 11.8 0.2 2.0 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF1104 PF06518.6 GAK62743.1 - 0.041 14.0 3.2 0.043 13.9 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) DUF1192 PF06698.6 GAK62743.1 - 0.052 13.3 3.3 0.062 13.1 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Atg14 PF10186.4 GAK62743.1 - 0.082 11.8 7.9 0.095 11.6 5.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Turandot PF07240.6 GAK62743.1 - 0.09 12.2 0.6 0.18 11.3 0.1 1.8 2 1 0 2 2 2 0 Stress-inducible humoral factor Turandot APG6 PF04111.7 GAK62743.1 - 0.1 11.6 8.1 0.14 11.2 5.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Hemagglutinin PF00509.13 GAK62743.1 - 0.11 10.6 2.2 0.11 10.6 1.0 1.4 1 1 0 1 1 1 0 Haemagglutinin MAP65_ASE1 PF03999.7 GAK62743.1 - 0.14 10.7 6.0 0.16 10.5 4.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Occludin_ELL PF07303.8 GAK62743.1 - 0.18 12.5 8.1 0.45 11.2 1.5 2.1 1 1 1 2 2 2 0 Occludin homology domain Prefoldin PF02996.12 GAK62743.1 - 0.29 10.8 12.7 0.062 12.9 3.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 GAK62743.1 - 0.3 11.1 11.4 0.4 10.7 7.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TcdA_TcdB PF12919.2 GAK62743.1 - 0.3 9.4 4.9 0.37 9.2 3.4 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Fib_alpha PF08702.5 GAK62743.1 - 0.43 10.7 9.4 1.7 8.7 6.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TSC22 PF01166.13 GAK62743.1 - 0.59 10.1 4.1 1 9.3 0.5 2.3 2 1 0 2 2 2 0 TSC-22/dip/bun family Macoilin PF09726.4 GAK62743.1 - 0.73 8.0 9.1 0.84 7.8 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF641 PF04859.7 GAK62743.1 - 0.76 9.5 10.4 0.71 9.6 3.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.2 GAK62743.1 - 0.82 9.5 14.7 0.2 11.4 2.4 2.1 1 1 1 2 2 2 0 Tropomyosin like Rootletin PF15035.1 GAK62743.1 - 1.2 9.1 8.0 0.34 10.8 3.0 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_13 PF13166.1 GAK62743.1 - 1.2 7.4 9.9 1.7 7.0 6.9 1.2 1 0 0 1 1 1 0 AAA domain Cluap1 PF10234.4 GAK62743.1 - 1.6 7.9 9.9 4.5 6.3 6.9 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 TMPIT PF07851.8 GAK62743.1 - 1.7 7.6 6.7 2.1 7.3 4.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.10 GAK62743.1 - 1.9 8.0 13.2 3.4 7.2 2.9 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 GAK62743.1 - 2 8.7 10.3 1.9 8.8 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 GAK62743.1 - 2.5 7.9 11.7 0.34 10.8 2.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FemAB PF02388.11 GAK62743.1 - 3 6.4 8.0 2 7.0 1.6 2.0 2 0 0 2 2 2 0 FemAB family CENP-F_leu_zip PF10473.4 GAK62743.1 - 3.3 7.5 12.4 1.3 8.8 2.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 GAK62743.1 - 3.4 7.9 8.6 1.7 8.9 2.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec5 PF15469.1 GAK62743.1 - 3.6 7.2 8.2 1.2 8.8 0.5 2.1 1 1 1 2 2 2 0 Exocyst complex component Sec5 DivIVA PF05103.8 GAK62743.1 - 4.6 7.3 14.3 7.5 6.6 3.4 2.1 1 1 1 2 2 2 0 DivIVA protein ISG65-75 PF11727.3 GAK62743.1 - 4.9 6.1 9.0 2.2 7.2 3.0 1.9 1 1 1 2 2 2 0 Invariant surface glycoprotein BRE1 PF08647.6 GAK62743.1 - 5.2 7.1 13.1 0.13 12.2 1.1 2.4 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.6 GAK62743.1 - 8 5.0 11.8 12 4.4 8.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.1 GAK62743.1 - 9.9 6.5 9.4 33 4.8 5.1 2.2 1 1 1 2 2 2 0 Snapin/Pallidin RNA_lig_T4_1 PF09511.5 GAK62744.1 - 3.2e-74 249.1 0.0 4.7e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 GAK62744.1 - 5.5e-20 71.9 0.0 9.1e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 GAK62744.1 - 2.6e-17 62.8 0.0 5.6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_33 PF13671.1 GAK62744.1 - 0.00056 19.8 0.1 0.0025 17.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK62744.1 - 0.00072 20.3 0.0 0.0023 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAK62744.1 - 0.096 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NAM-associated PF14303.1 GAK62744.1 - 1.5 9.0 10.1 3.2 8.0 7.0 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ecl1 PF12855.2 GAK62746.1 - 5.8e-05 22.2 0.2 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 Life-span regulatory factor NicO PF03824.11 GAK62746.1 - 3.5 6.8 21.0 7.7 5.7 14.6 1.5 1 0 0 1 1 1 0 High-affinity nickel-transport protein AA_kinase PF00696.23 GAK62748.1 - 3.9e-37 128.1 0.3 2e-31 109.4 0.0 2.2 1 1 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 GAK62748.1 - 7.7e-12 44.4 0.1 1.6e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 GAK62748.1 - 4.1e-10 39.0 1.3 3.2e-07 29.7 0.1 2.6 2 0 0 2 2 2 2 ACT domain DUF1517 PF07466.6 GAK62749.1 - 0.026 13.5 0.1 0.026 13.5 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1517) WH2 PF02205.15 GAK62750.1 - 4.4e-08 32.4 0.7 9.3e-08 31.4 0.1 1.9 2 0 0 2 2 2 1 WH2 motif Cellulase PF00150.13 GAK62753.1 - 1.7e-12 47.1 7.0 1e-11 44.5 4.9 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PRMT5 PF05185.11 GAK62754.1 - 1.2e-09 37.6 0.0 1.8e-08 33.7 0.0 2.2 2 1 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 GAK62754.1 - 2.9e-05 24.6 0.1 0.00018 22.0 0.0 2.3 2 2 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 GAK62754.1 - 0.00019 20.6 0.1 0.00037 19.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 GAK62754.1 - 0.0002 21.3 0.1 0.17 11.9 0.0 3.0 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 GAK62754.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 GAK62754.1 - 0.0033 17.4 0.1 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain MTS PF05175.9 GAK62754.1 - 0.017 14.5 0.0 0.04 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 GAK62754.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 GAK62754.1 - 0.031 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.1 GAK62754.1 - 0.031 13.8 0.0 0.15 11.6 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Prolamin_like PF05617.6 GAK62754.1 - 0.033 14.3 0.4 0.088 12.9 0.1 1.8 2 0 0 2 2 2 0 Prolamin-like Methyltransf_9 PF08003.6 GAK62754.1 - 0.034 12.8 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.7 GAK62754.1 - 0.086 13.3 0.1 1.8 9.1 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Bromodomain PF00439.20 GAK62755.1 - 5.2e-21 74.3 0.0 9.4e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain adh_short PF00106.20 GAK62756.1 - 2.8e-13 50.1 0.3 6.3e-13 48.9 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK62756.1 - 2e-05 24.3 0.1 3.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAK62756.1 - 0.034 14.1 0.0 2.8 7.8 0.0 2.3 1 1 1 2 2 2 0 NADH(P)-binding Dus PF01207.12 GAK62757.1 - 4.6e-69 232.6 0.0 9.5e-69 231.5 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) YTH PF04146.10 GAK62758.1 - 5.1e-48 162.2 0.0 1.2e-47 161.0 0.0 1.6 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 GAK62758.1 - 0.00061 19.3 0.0 0.96 9.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK62758.1 - 0.0098 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK62758.1 - 0.085 12.8 0.0 18 5.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SURF1 PF02104.10 GAK62761.1 - 5.5e-42 143.9 0.0 1.3e-41 142.8 0.0 1.5 1 0 0 1 1 1 1 SURF1 family UAA PF08449.6 GAK62762.1 - 2.5e-75 253.2 4.0 9.6e-75 251.3 2.8 1.7 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 GAK62762.1 - 0.026 13.6 0.7 0.07 12.2 0.5 1.7 1 1 0 1 1 1 0 Nucleotide-sugar transporter TPT PF03151.11 GAK62762.1 - 1.8 8.1 12.5 0.083 12.5 2.1 2.7 3 0 0 3 3 3 0 Triose-phosphate Transporter family Metallophos PF00149.23 GAK62764.1 - 4.8e-08 32.6 3.2 9.5e-08 31.6 2.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NTR2 PF15458.1 GAK62764.1 - 0.033 13.4 3.4 0.052 12.7 2.4 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Spt5_N PF11942.3 GAK62764.1 - 5.7 7.6 11.2 0.55 10.8 3.2 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal IPK PF03770.11 GAK62765.1 - 1.3e-50 171.7 0.0 1.9e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Nucleo_P87 PF07267.6 GAK62765.1 - 0.98 8.0 0.3 2.4 6.7 0.1 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Kelch_6 PF13964.1 GAK62766.1 - 2.9e-11 43.0 0.2 0.011 15.8 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAK62766.1 - 1.5e-10 40.6 0.1 0.018 14.7 0.0 4.7 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAK62766.1 - 2.9e-08 33.4 1.1 6.1e-05 22.8 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAK62766.1 - 7.4e-07 29.1 4.9 3.7e-05 23.7 0.0 5.1 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAK62766.1 - 5e-06 26.0 0.2 0.92 9.3 0.0 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 GAK62766.1 - 0.0024 17.3 0.0 1.1 8.8 0.0 3.4 3 0 0 3 3 3 1 Kelch motif AMP-binding PF00501.23 GAK62768.1 - 8e-81 271.5 0.0 1.3e-80 270.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK62768.1 - 6.7e-07 30.1 0.1 2e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNase_PH PF01138.16 GAK62769.1 - 5.9e-32 110.7 0.0 9.7e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAK62769.1 - 0.0014 18.5 0.0 0.0034 17.2 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Fimbrial_CS1 PF04449.7 GAK62769.1 - 0.058 13.4 0.4 4.5 7.3 0.1 2.3 2 0 0 2 2 2 0 CS1 type fimbrial major subunit Cullin PF00888.17 GAK62770.1 - 3.8e-31 108.2 0.0 6e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family Proteasome PF00227.21 GAK62771.1 - 2.4e-32 111.7 0.0 5e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit Condensation PF00668.15 GAK62771.1 - 0.034 13.0 0.0 5.3 5.7 0.0 2.3 2 0 0 2 2 2 0 Condensation domain AATase PF07247.7 GAK62771.1 - 0.063 11.8 0.0 0.48 8.9 0.0 1.9 1 1 0 1 1 1 0 Alcohol acetyltransferase HTH_10 PF04967.7 GAK62772.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain DUF3712 PF12505.3 GAK62773.1 - 1.1e-100 332.3 46.2 9.4e-22 77.3 0.0 9.4 9 1 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 GAK62773.1 - 3.6e-07 30.4 19.1 1.8 8.9 0.0 8.4 8 0 0 8 8 8 5 Late embryogenesis abundant protein Adeno_E1B_55K_N PF04623.7 GAK62775.1 - 6.2 7.3 8.7 5.9 7.4 0.0 2.7 3 0 0 3 3 3 0 Adenovirus E1B protein N-terminus Glyco_hydro_16 PF00722.16 GAK62776.1 - 7.8e-37 126.3 2.4 7.8e-37 126.3 1.7 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF2360 PF10152.4 GAK62777.1 - 0.022 15.0 4.1 0.029 14.6 2.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DEPP PF15343.1 GAK62777.1 - 0.05 13.2 0.2 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Decidual protein induced by progesterone family Metallophos PF00149.23 GAK62778.1 - 2.2e-41 141.4 0.7 3.3e-41 140.8 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GTP_EFTU_D3 PF03143.12 GAK62779.1 - 4.1e-37 126.3 0.0 6e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAK62779.1 - 7.8e-05 22.7 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RabGAP-TBC PF00566.13 GAK62780.1 - 1.3e-49 168.6 0.0 2e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 GAK62780.1 - 1.4e-06 27.7 0.0 3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Meth_synt_2 PF01717.13 GAK62781.1 - 1.9e-145 483.8 0.0 2.4e-136 453.9 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAK62781.1 - 5.4e-124 413.5 0.0 2.2e-111 372.0 0.1 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 GAK62781.1 - 0.0024 16.8 0.1 0.071 12.0 0.0 2.7 3 0 0 3 3 3 1 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.4 GAK62781.1 - 0.035 13.5 0.5 0.088 12.3 0.4 1.7 1 0 0 1 1 1 0 Short C-terminal domain DUF726 PF05277.7 GAK62782.1 - 3.3e-54 184.0 0.8 5e-54 183.4 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 GAK62782.1 - 1.3e-05 25.2 0.1 3.9e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK62782.1 - 0.00023 20.9 0.1 0.00064 19.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAK62782.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 GAK62782.1 - 0.31 9.9 0.0 0.52 9.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ubiquitin PF00240.18 GAK62783.1 - 2.9e-19 68.2 0.2 4.7e-19 67.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAK62783.1 - 2.8e-09 36.5 0.3 4.1e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 GAK62783.1 - 9.4e-07 28.5 0.3 3.2e-06 26.7 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.4 GAK62783.1 - 4e-06 26.9 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAK62783.1 - 0.00072 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAK62783.1 - 0.035 14.3 0.1 0.087 13.0 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain DUF4504 PF14953.1 GAK62786.1 - 6.5e-12 45.3 1.2 3.5e-05 23.2 0.2 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) FRG1 PF06229.7 GAK62787.1 - 8.6e-20 70.9 4.2 3.2e-18 65.8 2.9 3.1 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 GAK62787.1 - 4.9e-05 23.3 0.1 0.00022 21.2 0.0 2.0 1 1 1 2 2 2 1 Fascin domain SPT2 PF08243.6 GAK62787.1 - 0.94 9.8 8.4 0.14 12.4 0.7 2.5 3 0 0 3 3 3 0 SPT2 chromatin protein Ribosomal_L13 PF00572.13 GAK62788.1 - 1.4e-25 89.7 0.0 2.7e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L32e PF01655.13 GAK62789.1 - 8.1e-48 161.0 2.8 9.6e-48 160.8 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 TAFII55_N PF04658.8 GAK62790.1 - 2.6e-53 179.8 0.1 6.1e-53 178.6 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region GTP_EFTU PF00009.22 GAK62791.1 - 1.5e-55 187.6 0.1 2.1e-55 187.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAK62791.1 - 2.4e-36 123.8 0.0 5.5e-36 122.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAK62791.1 - 5.7e-15 55.1 1.6 5.7e-15 55.1 1.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 GAK62791.1 - 0.0011 18.6 0.5 0.0026 17.3 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 GAK62791.1 - 0.0024 17.8 0.4 0.0077 16.1 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyoxal_oxid_N PF07250.6 GAK62793.1 - 1.1e-46 158.9 0.0 5.7e-45 153.2 0.0 2.9 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 GAK62793.1 - 3.6e-26 91.1 0.1 6.9e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Tfb4 PF03850.9 GAK62794.1 - 1.1e-70 238.0 5.5 4.6e-69 232.7 3.8 2.2 1 1 0 1 1 1 1 Transcription factor Tfb4 DEAD PF00270.24 GAK62795.1 - 5.9e-36 123.4 0.0 2.3e-35 121.5 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK62795.1 - 9.7e-20 70.2 0.0 2.9e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK62795.1 - 7.2e-08 32.4 0.0 2.1e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 GAK62795.1 - 0.0008 19.1 0.4 0.0026 17.4 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAK62795.1 - 0.0042 17.2 1.1 0.11 12.6 0.5 2.9 2 1 0 2 2 2 1 AAA domain Rep_fac_C PF08542.6 GAK62797.1 - 3.2e-21 75.1 0.0 8.2e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAK62797.1 - 2.6e-11 43.4 0.0 3.9e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAK62797.1 - 5.2e-05 23.4 0.5 0.00018 21.6 0.3 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAK62797.1 - 0.00032 20.8 0.2 0.0013 18.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 GAK62797.1 - 0.00072 18.3 0.0 0.0071 15.0 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 GAK62797.1 - 0.0017 18.3 0.1 0.087 12.8 0.1 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 GAK62797.1 - 0.0028 17.5 0.1 0.0072 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 GAK62797.1 - 0.011 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_16 PF13191.1 GAK62797.1 - 0.013 15.5 0.3 0.16 11.9 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 GAK62797.1 - 0.014 14.8 0.0 0.04 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_11 PF13086.1 GAK62797.1 - 0.035 13.6 0.1 0.44 10.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 GAK62797.1 - 0.052 12.5 0.0 0.45 9.5 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 GAK62797.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NTP_transf_2 PF01909.18 GAK62798.1 - 1.4e-05 25.3 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 GAK62798.1 - 8.6e-05 22.4 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase BEX PF04538.7 GAK62798.1 - 6.3 7.0 10.8 0.086 13.0 1.1 2.4 2 1 0 2 2 2 0 Brain expressed X-linked like family SUZ PF12752.2 GAK62799.1 - 5.5e-12 46.0 1.5 5.5e-12 46.0 1.1 2.4 2 0 0 2 2 2 1 SUZ domain MRP-L28 PF09812.4 GAK62799.1 - 0.058 13.2 0.2 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Mito_carr PF00153.22 GAK62800.1 - 4.3e-65 215.4 5.3 7.1e-23 80.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein I_LWEQ PF01608.12 GAK62801.1 - 6.1 6.7 10.6 25 4.7 3.1 2.6 2 0 0 2 2 2 0 I/LWEQ domain Zn_clus PF00172.13 GAK62802.1 - 0.0016 18.2 11.4 0.0027 17.5 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 GAK62802.1 - 3.8 6.2 10.7 0.24 10.1 3.9 1.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor IGR PF09597.5 GAK62805.1 - 4e-11 42.6 0.2 7.8e-11 41.7 0.2 1.5 1 1 0 1 1 1 1 IGR protein motif 60KD_IMP PF02096.15 GAK62806.1 - 2.1e-16 60.1 0.0 6.9e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 60Kd inner membrane protein HJURP_C PF12347.3 GAK62806.1 - 0.052 13.1 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat DEAD PF00270.24 GAK62807.1 - 5.4e-19 68.3 0.0 3.9e-18 65.4 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK62807.1 - 6.7e-19 67.5 0.0 2e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK62807.1 - 1.3e-18 67.5 0.0 3.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EF-hand_1 PF00036.27 GAK62808.1 - 2e-26 89.2 17.1 2.1e-09 35.9 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAK62808.1 - 2.8e-25 88.2 12.5 1.1e-12 47.9 2.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAK62808.1 - 3.8e-25 85.4 13.2 1.2e-08 34.1 0.1 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 GAK62808.1 - 5.3e-18 64.3 16.3 1.7e-11 43.5 1.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 GAK62808.1 - 2.3e-16 58.2 14.5 5.4e-06 25.5 0.1 4.1 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 GAK62808.1 - 4.4e-10 39.3 0.8 0.00078 19.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 GAK62808.1 - 8e-08 31.9 3.1 0.00083 19.0 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 GAK62808.1 - 0.0071 15.9 0.2 0.2 11.1 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein LTXXQ PF07813.7 GAK62808.1 - 0.017 15.5 0.6 0.23 11.9 0.1 2.3 2 0 0 2 2 2 0 LTXXQ motif family protein DUF1636 PF07845.6 GAK62808.1 - 0.023 14.9 0.0 1.1 9.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1636) SPARC_Ca_bdg PF10591.4 GAK62808.1 - 0.049 13.6 3.9 1.3 9.0 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Metal_resist PF13801.1 GAK62808.1 - 0.16 11.9 1.2 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance G-patch PF01585.18 GAK62809.1 - 6.5e-13 48.2 0.8 3.4e-12 45.9 0.4 2.5 2 0 0 2 2 2 1 G-patch domain R3H PF01424.17 GAK62809.1 - 6.1e-10 38.6 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 GAK62809.1 - 1.7e-05 24.5 0.6 0.00014 21.6 0.4 2.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site AAA_22 PF13401.1 GAK62809.1 - 0.14 12.2 0.3 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3317 PF11779.3 GAK62810.1 - 4.4e-15 54.8 4.1 6.8e-15 54.2 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Caa3_CtaG PF09678.5 GAK62810.1 - 0.0023 16.9 1.8 0.0031 16.5 1.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Mit_KHE1 PF10173.4 GAK62810.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RAP1 PF07218.6 GAK62810.1 - 1.1 7.2 7.7 1.3 7.0 5.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.8 GAK62810.1 - 1.5 6.5 11.1 1.8 6.2 7.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PCI PF01399.22 GAK62811.1 - 3.2e-05 24.1 0.0 6.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain Apc3 PF12895.2 GAK62811.1 - 0.04 14.0 1.6 0.22 11.6 1.1 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAK62811.1 - 6 7.7 7.0 23 5.9 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.18 GAK62812.1 - 3.7e-15 55.7 0.8 3.7e-15 55.7 0.5 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAK62812.1 - 2.1e-07 30.9 0.3 2.9e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HSP70 PF00012.15 GAK62813.1 - 1.6e-61 207.9 4.1 2e-55 187.8 0.0 2.7 2 1 0 2 2 2 2 Hsp70 protein Ras PF00071.17 GAK62813.1 - 5.3e-56 188.4 0.0 9.9e-56 187.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK62813.1 - 1e-17 64.7 0.0 2.8e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK62813.1 - 2.2e-14 53.0 0.2 9e-14 51.0 0.0 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAK62813.1 - 9.2e-06 24.9 0.0 1.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAK62813.1 - 0.0044 16.9 0.0 0.041 13.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase MreB_Mbl PF06723.8 GAK62813.1 - 0.025 13.2 0.1 0.058 11.9 0.1 1.5 1 0 0 1 1 1 0 MreB/Mbl protein GTP_EFTU PF00009.22 GAK62813.1 - 0.035 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain UCH PF00443.24 GAK62814.1 - 1.7e-49 168.3 0.0 3.3e-49 167.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK62814.1 - 8.1e-20 71.4 0.0 5.9e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAK62814.1 - 7.2e-12 45.2 2.3 7.2e-12 45.2 1.6 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Abhydrolase_3 PF07859.8 GAK62815.1 - 2.1e-19 69.9 0.2 3.9e-17 62.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 GAK62815.1 - 2.2e-10 39.7 0.0 1.2e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 GAK62815.1 - 0.023 14.9 0.8 0.047 13.9 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain Methyltransf_15 PF09445.5 GAK62816.1 - 1.6e-32 112.3 0.0 2.4e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 GAK62816.1 - 2.1e-08 34.2 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAK62816.1 - 1e-05 25.2 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 GAK62816.1 - 0.0022 18.5 0.0 0.0051 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Adeno_hexon PF01065.14 GAK62816.1 - 0.031 13.1 0.2 0.043 12.6 0.1 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Methyltransf_3 PF01596.12 GAK62816.1 - 0.075 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 GAK62816.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Mo25 PF08569.6 GAK62818.1 - 1.2e-127 425.6 1.0 2.1e-127 424.8 0.7 1.3 1 1 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 GAK62818.1 - 0.047 13.9 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats DUF544 PF04424.8 GAK62818.1 - 0.098 12.4 0.5 2.9 7.7 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF544) GP40 PF11025.3 GAK62818.1 - 0.29 10.7 2.7 0.52 9.8 1.9 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Period_C PF12114.3 GAK62818.1 - 2 7.9 7.0 3.7 7.0 4.8 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.4 GAK62818.1 - 5.3 6.4 9.0 7.9 5.8 6.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 GAK62818.1 - 5.7 6.9 12.8 11 6.0 8.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3518 PF12031.3 GAK62819.1 - 0.0031 16.3 0.0 0.0031 16.3 0.0 2.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3518) HEAT PF02985.17 GAK62819.1 - 0.13 12.4 1.1 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat Rod_cone_degen PF15201.1 GAK62819.1 - 6.7 6.6 7.3 2.4 8.0 1.3 3.0 2 0 0 2 2 2 0 Progressive rod-cone degeneration Peptidase_M41 PF01434.13 GAK62821.1 - 2.7e-72 242.7 0.5 5e-72 241.8 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 GAK62821.1 - 9.4e-43 145.5 0.0 2.2e-42 144.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 GAK62821.1 - 6e-10 39.2 0.0 1.4e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 GAK62821.1 - 0.00021 21.4 0.0 0.042 13.9 0.0 2.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAK62821.1 - 0.0029 16.3 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 GAK62821.1 - 0.003 17.2 0.5 0.012 15.4 0.3 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAK62821.1 - 0.0099 16.6 0.0 0.038 14.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAK62821.1 - 0.011 15.7 0.2 0.11 12.4 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 GAK62821.1 - 0.011 15.6 0.2 0.053 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAK62821.1 - 0.012 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAK62821.1 - 0.015 14.9 0.9 0.047 13.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 GAK62821.1 - 0.02 14.0 0.0 0.057 12.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 GAK62821.1 - 0.03 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 GAK62821.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAK62821.1 - 0.076 12.3 0.6 0.24 10.7 0.3 2.0 1 1 1 2 2 2 0 AAA domain Drf_GBD PF06371.8 GAK62822.1 - 5.7e-10 38.8 0.0 3.6e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Rcd1 PF04078.8 GAK62822.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Kinesin PF00225.18 GAK62823.1 - 3.7e-111 371.0 0.0 6.8e-111 370.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3450 PF11932.3 GAK62823.1 - 0.0025 17.1 1.9 0.0025 17.1 1.3 5.2 3 1 2 5 5 5 1 Protein of unknown function (DUF3450) FlaC_arch PF05377.6 GAK62823.1 - 10 6.1 6.6 16 5.4 0.6 4.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GATA PF00320.22 GAK62824.1 - 2.2e-13 49.2 6.3 4.6e-13 48.2 4.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 GAK62824.1 - 0.002 18.1 0.5 0.023 14.7 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.6 GAK62824.1 - 0.19 11.8 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold GCD14 PF08704.5 GAK62826.1 - 6.9e-80 268.0 3.7 7.6e-46 156.6 2.0 3.2 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 GAK62826.1 - 0.023 14.6 0.1 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Daxx PF03344.10 GAK62826.1 - 0.078 11.4 7.6 0.12 10.8 5.2 1.2 1 0 0 1 1 1 0 Daxx Family Radical_SAM PF04055.16 GAK62826.1 - 0.084 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily TRM13 PF05206.9 GAK62826.1 - 0.11 11.7 0.2 6.9 5.8 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase TRM13 RR_TM4-6 PF06459.7 GAK62826.1 - 0.13 12.1 2.2 0.22 11.3 1.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Methyltransf_24 PF13578.1 GAK62826.1 - 4.8 8.0 5.7 11 6.8 1.9 2.7 2 1 0 2 2 2 0 Methyltransferase domain Velvet PF11754.3 GAK62828.1 - 6.9e-49 166.2 0.5 6.5e-34 117.3 0.0 2.6 2 0 0 2 2 2 2 Velvet factor LSM PF01423.17 GAK62829.1 - 9.5e-18 63.5 0.3 1.4e-17 63.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAK62829.1 - 4.4e-06 26.5 0.3 6.5e-06 25.9 0.1 1.4 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.2 GAK62829.1 - 0.029 14.1 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain DUF3007 PF11460.3 GAK62830.1 - 0.12 12.4 0.7 0.21 11.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF3384 PF11864.3 GAK62831.1 - 3.5e-106 355.4 0.0 1.2e-100 337.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 GAK62831.1 - 1e-51 175.0 0.0 1.7e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 GAK62831.1 - 3.6e-27 95.3 9.6 2.3e-25 89.4 6.2 3.2 2 1 0 2 2 2 1 Tuberin UCR_hinge PF02320.11 GAK62832.1 - 6.4e-20 70.8 3.2 6.4e-20 70.8 2.3 1.7 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein CENP-B_dimeris PF09026.5 GAK62832.1 - 0.014 15.6 13.8 0.023 14.9 9.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YqfQ PF14181.1 GAK62832.1 - 0.02 14.9 1.7 0.027 14.4 1.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein Na_trans_assoc PF06512.8 GAK62832.1 - 0.055 13.4 6.7 0.06 13.3 4.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Sigma70_ner PF04546.8 GAK62832.1 - 0.055 13.0 6.8 0.058 12.9 4.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Tim54 PF11711.3 GAK62832.1 - 0.12 10.9 2.6 0.12 10.9 1.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Myc_N PF01056.13 GAK62832.1 - 0.16 11.1 8.2 0.18 10.9 5.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 GAK62832.1 - 0.24 9.2 2.0 0.24 9.2 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 GAK62832.1 - 0.29 9.1 4.6 0.28 9.1 3.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 GAK62832.1 - 0.33 9.4 13.0 0.35 9.3 9.0 1.1 1 0 0 1 1 1 0 Daxx Family RNA_pol_3_Rpc31 PF11705.3 GAK62832.1 - 0.37 10.6 8.8 0.5 10.2 6.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.1 GAK62832.1 - 0.39 10.3 3.8 0.49 10.0 2.6 1.3 1 0 0 1 1 1 0 FAM176 family CobT PF06213.7 GAK62832.1 - 0.5 9.4 10.0 0.63 9.1 6.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VID27 PF08553.5 GAK62832.1 - 0.59 8.2 8.8 0.68 8.0 6.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 GAK62832.1 - 0.6 7.9 10.3 0.66 7.8 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 GAK62832.1 - 0.8 9.0 7.2 0.96 8.7 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRN3 PF05327.6 GAK62832.1 - 0.91 7.5 4.1 3.8 5.5 1.9 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.6 GAK62832.1 - 1.2 8.9 6.1 1.5 8.5 4.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAP_alpha PF03896.11 GAK62832.1 - 1.5 7.7 5.6 1.6 7.6 3.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Radial_spoke PF04712.7 GAK62832.1 - 1.5 7.4 10.6 1.9 7.1 7.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Nucleoplasmin PF03066.10 GAK62832.1 - 2.2 7.7 16.3 3.1 7.2 11.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin GCP5-Mod21 PF14609.1 GAK62832.1 - 2.5 6.1 5.4 3 5.8 3.7 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 SDA1 PF05285.7 GAK62832.1 - 2.8 7.1 9.7 3.1 6.9 6.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 GAK62832.1 - 3.8 6.1 11.0 3.9 6.0 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 GAK62832.1 - 4.5 5.8 9.8 5 5.7 6.8 1.1 1 0 0 1 1 1 0 Paf1 DUF2890 PF11081.3 GAK62832.1 - 5.8 6.9 13.7 8.1 6.4 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Adeno_terminal PF02459.10 GAK62832.1 - 6.7 4.7 5.6 8.2 4.4 3.9 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Pox_RNA_Pol_19 PF05320.7 GAK62832.1 - 9.6 5.9 8.6 13 5.4 6.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Aminotran_1_2 PF00155.16 GAK62833.1 - 1.3e-52 179.0 0.0 2.8e-49 167.9 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAK62833.1 - 0.00021 20.5 0.0 0.0004 19.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 GAK62833.1 - 0.011 14.2 0.0 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 GAK62833.1 - 0.083 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SAMP PF05924.6 GAK62833.1 - 0.1 11.7 1.4 0.16 11.1 0.1 2.1 2 0 0 2 2 2 0 SAMP Motif Ribosomal_L24e PF01246.15 GAK62834.1 - 4.8e-22 77.6 5.3 1.4e-19 69.6 0.2 3.1 3 0 0 3 3 3 2 Ribosomal protein L24e DUF619 PF04768.8 GAK62836.1 - 1.6e-46 157.8 0.0 3.4e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 GAK62836.1 - 2.8e-25 88.9 0.0 1e-24 87.1 0.0 2.0 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 GAK62836.1 - 6.5e-21 74.9 0.0 2.1e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 Amino acid kinase family HLH PF00010.21 GAK62836.1 - 1.2e-08 34.5 0.1 2.8e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Med15 PF09606.5 GAK62836.1 - 0.023 12.9 33.7 0.045 11.9 23.3 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DapB_N PF01113.15 GAK62836.1 - 0.036 13.9 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PAT1 PF09770.4 GAK62836.1 - 0.61 8.2 21.0 1.1 7.4 14.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 GAK62836.1 - 2.7 7.7 11.8 5.7 6.7 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Activator_LAG-3 PF11498.3 GAK62836.1 - 9.1 4.8 38.3 15 4.1 26.5 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 zf-C2H2 PF00096.21 GAK62838.1 - 3e-10 39.7 13.2 1.1e-05 25.4 2.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK62838.1 - 1e-07 31.7 12.0 0.00099 19.2 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAK62838.1 - 5.6e-06 26.3 3.0 5.6e-06 26.3 2.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain SIN1 PF05422.7 GAK62839.1 - 4.5e-30 104.6 0.0 1.2e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RA PF00788.18 GAK62839.1 - 0.015 15.7 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Myb_DNA-bind_6 PF13921.1 GAK62840.1 - 0.0092 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4128 PF13554.1 GAK62840.1 - 0.058 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function RasGAP PF00616.14 GAK62841.1 - 6.5e-56 189.1 0.7 2e-55 187.5 0.0 2.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 GAK62841.1 - 1.8e-41 141.1 2.0 1.9e-41 141.0 0.2 2.0 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 GAK62841.1 - 0.0015 18.8 2.1 0.28 11.5 0.1 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF972) KxDL PF10241.4 GAK62841.1 - 0.77 9.7 6.3 2.4 8.0 0.1 4.0 4 0 0 4 4 4 0 Uncharacterized conserved protein Spc97_Spc98 PF04130.8 GAK62842.1 - 1.6e-117 393.0 0.0 2.6e-117 392.4 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF776 PF05604.6 GAK62843.1 - 0.084 13.0 3.7 0.53 10.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF776) Kin17_mid PF10357.4 GAK62845.1 - 3.6e-48 162.3 0.2 6.3e-48 161.6 0.1 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 GAK62845.1 - 3.5e-06 26.9 2.4 6.9e-06 26.0 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAK62845.1 - 2.2e-05 24.4 1.7 4.5e-05 23.4 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAK62845.1 - 0.0087 16.1 0.6 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 GAK62845.1 - 0.01 15.5 0.6 0.032 14.0 0.4 1.9 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 GAK62845.1 - 0.13 12.6 1.7 0.29 11.5 1.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Pkinase PF00069.20 GAK62846.1 - 5.5e-53 179.7 0.0 4.6e-49 166.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62846.1 - 3.2e-21 75.5 0.0 2.9e-18 65.8 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK62846.1 - 0.0027 16.7 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK62846.1 - 0.0034 17.1 0.7 0.013 15.2 0.5 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAK62846.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RGS PF00615.14 GAK62847.1 - 6e-13 48.9 0.0 1.7e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Cyt-b5 PF00173.23 GAK62848.1 - 2.4e-14 52.8 0.0 4.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 GAK62848.1 - 1.7e-13 50.5 26.8 1.7e-13 50.5 18.6 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lactamase_B PF00753.22 GAK62848.1 - 0.0059 16.2 0.4 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily SHMT PF00464.14 GAK62850.1 - 7.7e-176 584.3 0.0 9.4e-176 584.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 GAK62850.1 - 0.00084 18.5 0.0 0.0021 17.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase MAPEG PF01124.13 GAK62850.1 - 0.093 12.3 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 MAPEG family SNARE_assoc PF09335.6 GAK62851.1 - 3.3e-30 104.8 7.4 1.1e-29 103.1 4.6 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein DHH PF01368.15 GAK62852.1 - 4.7e-08 32.7 0.0 1.8e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 DHH family Ribonuc_2-5A PF06479.7 GAK62852.1 - 0.013 15.3 3.0 0.68 9.7 0.3 2.5 2 1 0 2 2 2 0 Ribonuclease 2-5A DHHA2 PF02833.9 GAK62852.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.5 1 1 0 1 1 1 0 DHHA2 domain Cys_Met_Meta_PP PF01053.15 GAK62855.1 - 3.4e-139 463.4 0.0 9.4e-139 461.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAK62855.1 - 0.006 15.6 0.1 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family ADK PF00406.17 GAK62856.1 - 5.8e-05 23.0 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 GAK62856.1 - 0.00053 20.7 1.0 0.0014 19.4 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAK62856.1 - 0.037 13.8 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAK62856.1 - 0.042 13.8 1.2 1.2 9.1 0.1 2.9 1 1 2 3 3 3 0 AAA ATPase domain AAA_18 PF13238.1 GAK62856.1 - 0.061 13.6 1.5 0.11 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 GAK62856.1 - 0.075 12.9 0.2 0.87 9.4 0.1 2.6 2 1 0 2 2 2 0 AAA domain SIR2 PF02146.12 GAK62857.1 - 8.6e-57 191.7 0.0 1.6e-56 190.8 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 GAK62857.1 - 1.9e-09 37.2 0.2 1.2e-05 24.9 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF592) SURF2 PF05477.6 GAK62857.1 - 0.009 15.1 1.0 0.021 13.9 0.7 1.5 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) CutC PF03932.9 GAK62857.1 - 0.016 14.4 0.0 0.045 13.0 0.0 1.7 2 0 0 2 2 2 0 CutC family DUF1323 PF07037.6 GAK62857.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) TPPII_N PF12583.3 GAK62857.1 - 0.75 9.9 6.4 1.2 9.2 4.5 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal NGP1NT PF08153.7 GAK62858.1 - 2.2e-42 144.0 0.0 5.1e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 GAK62858.1 - 4.2e-18 65.3 0.0 8e-15 54.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK62858.1 - 1.2e-05 24.6 0.2 4.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 GAK62858.1 - 0.00027 20.2 0.1 0.057 12.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAK62858.1 - 0.0011 18.4 0.1 0.24 10.8 0.0 3.1 1 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAK62858.1 - 0.0027 16.8 0.0 0.0059 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAK62858.1 - 0.15 11.9 8.1 0.38 10.5 0.0 4.0 4 1 1 5 5 5 0 Dynamin family DCP2 PF05026.8 GAK62859.1 - 1.2e-31 108.3 0.0 2e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain DUF427 PF04248.7 GAK62859.1 - 1.3e-27 95.2 0.7 4.9e-27 93.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF427) NUDIX PF00293.23 GAK62859.1 - 1.2e-15 57.3 0.0 2.3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Transaldolase PF00923.14 GAK62859.1 - 0.074 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Transaldolase zf-RING_2 PF13639.1 GAK62860.1 - 1.4e-07 31.1 8.1 1.4e-07 31.1 5.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-CCCH PF00642.19 GAK62860.1 - 1.7e-07 30.7 3.5 1.7e-07 30.7 2.4 3.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 GAK62860.1 - 3.9e-07 29.6 6.3 3.9e-07 29.6 4.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK62860.1 - 6.5e-06 25.7 5.4 1.8e-05 24.3 3.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK62860.1 - 2.1e-05 24.1 7.5 6.4e-05 22.5 5.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAK62860.1 - 5.4e-05 23.1 8.2 0.00011 22.1 5.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAK62860.1 - 0.011 15.6 7.0 0.027 14.3 4.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 GAK62860.1 - 0.11 12.6 6.0 0.34 11.0 4.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAK62860.1 - 0.14 11.8 3.5 0.35 10.6 2.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 GAK62860.1 - 0.38 10.6 3.9 1.4 8.7 2.8 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 GAK62860.1 - 1.9 8.5 7.6 0.25 11.3 1.7 2.3 2 0 0 2 2 2 0 zinc-finger RPE65 PF03055.10 GAK62861.1 - 4.9e-135 450.8 0.0 5.8e-135 450.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SNF2_N PF00176.18 GAK62862.1 - 2.1e-47 161.3 0.0 3e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK62862.1 - 7.4e-18 64.1 0.0 4.6e-16 58.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.1 GAK62862.1 - 1.6e-12 47.1 0.0 5.5e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.10 GAK62862.1 - 0.0005 19.9 0.0 0.0034 17.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF566 PF04484.7 GAK62863.1 - 3.8 6.9 16.3 5.8 6.3 11.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 GAK62863.1 - 4.1 5.5 14.7 4.7 5.3 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Elf1 PF05129.8 GAK62865.1 - 6e-30 102.7 0.5 6.7e-30 102.6 0.3 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-BED PF02892.10 GAK62865.1 - 0.33 10.7 2.4 6.7 6.5 1.7 2.3 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.1 GAK62865.1 - 0.39 10.6 3.6 1.7 8.6 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 GAK62865.1 - 1.1 8.9 3.8 6.5 6.4 0.3 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Ank_4 PF13637.1 GAK62866.1 - 9.8e-14 51.4 0.3 1.4e-06 28.6 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAK62866.1 - 1.1e-11 44.8 0.1 3.4e-09 36.9 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAK62866.1 - 3.4e-11 43.0 0.1 3e-08 33.6 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 GAK62866.1 - 4.3e-08 32.5 0.1 2.5e-06 26.9 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 GAK62866.1 - 1.7e-06 27.7 0.1 1.1e-05 25.2 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat HSP70 PF00012.15 GAK62867.1 - 9.5e-262 869.2 12.0 9.5e-262 869.2 8.3 1.7 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 GAK62867.1 - 1.9e-18 66.1 0.3 1.1e-17 63.7 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein zf-U1 PF06220.7 GAK62867.1 - 1.4e-07 30.9 0.7 2.9e-07 29.9 0.5 1.6 1 0 0 1 1 1 1 U1 zinc finger Hydantoinase_A PF01968.13 GAK62867.1 - 0.013 14.6 6.8 0.058 12.4 0.2 3.4 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2680 PF10925.3 GAK62867.1 - 0.31 10.9 3.8 0.65 9.9 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) Seryl_tRNA_N PF02403.17 GAK62867.1 - 3.8 7.5 23.5 4.6 7.3 4.9 5.0 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain IU_nuc_hydro PF01156.14 GAK62868.1 - 3e-117 391.3 0.0 4.2e-117 390.8 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase S1-P1_nuclease PF02265.11 GAK62869.1 - 1.6e-47 162.2 0.0 1.3e-45 155.9 0.0 2.3 1 1 0 1 1 1 1 S1/P1 Nuclease LRR_4 PF12799.2 GAK62870.1 - 3.7e-07 29.6 2.1 0.64 9.7 0.1 5.3 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAK62870.1 - 0.00016 21.3 0.8 5.1 7.4 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 GAK62870.1 - 0.0061 16.4 1.8 5.8 7.3 0.0 5.1 5 1 0 5 5 5 1 Leucine Rich Repeat F-box PF00646.28 GAK62870.1 - 0.013 15.1 0.0 0.046 13.3 0.0 2.0 1 0 0 1 1 1 0 F-box domain Fibrillarin PF01269.12 GAK62870.1 - 0.099 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin LRR_7 PF13504.1 GAK62870.1 - 0.41 11.0 5.8 89 3.9 0.0 6.1 7 0 0 7 7 7 0 Leucine rich repeat ATP-synt_G PF04718.10 GAK62871.1 - 2.5e-20 73.0 0.3 4.3e-20 72.2 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit EF-hand_6 PF13405.1 GAK62872.1 - 5.5e-15 53.8 1.0 3.2e-06 26.5 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 GAK62872.1 - 3.3e-14 52.7 0.1 4e-08 33.2 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAK62872.1 - 2.8e-12 44.9 1.9 1.1e-05 24.3 0.0 3.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 GAK62872.1 - 5.9e-07 29.0 0.4 0.00065 19.2 0.0 3.6 1 1 3 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.1 GAK62872.1 - 7.7e-06 25.7 0.0 0.00081 19.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 GAK62872.1 - 1.1e-05 24.5 3.7 0.0051 16.0 0.3 2.9 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.5 GAK62872.1 - 0.00082 19.3 0.0 0.29 11.1 0.0 2.5 2 1 0 2 2 2 2 Ca2+ insensitive EF hand UPF0154 PF03672.8 GAK62872.1 - 0.045 13.3 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) RNA_pol_Rpb4 PF03874.11 GAK62872.1 - 0.048 13.6 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 Big_3_2 PF12245.3 GAK62872.1 - 0.071 12.6 0.4 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF3602 PF12223.3 GAK62873.1 - 1.6e-19 70.0 26.5 2.1e-16 60.0 5.4 4.2 1 1 3 4 4 4 3 Protein of unknown function (DUF3602) RNase_PH PF01138.16 GAK62874.1 - 1.2e-10 41.7 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAK62874.1 - 1.5e-08 34.4 0.0 7.1e-08 32.2 0.0 2.1 2 1 0 2 2 2 1 3' exoribonuclease family, domain 2 Methyltransf_23 PF13489.1 GAK62875.1 - 6.8e-16 58.4 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK62875.1 - 1.2e-14 54.5 0.0 7.4e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK62875.1 - 3.7e-09 36.0 0.0 6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAK62875.1 - 3.8e-08 33.0 0.0 8.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK62875.1 - 5.3e-08 33.4 0.0 1.3e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK62875.1 - 7.8e-08 32.5 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK62875.1 - 1.8e-07 31.5 0.0 5.5e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK62875.1 - 3e-07 30.4 0.0 1e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK62875.1 - 0.00014 21.2 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 GAK62875.1 - 0.055 12.5 0.0 0.16 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Skp1_POZ PF03931.10 GAK62876.1 - 1.1e-09 38.2 0.0 4e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Myb_DNA-bind_6 PF13921.1 GAK62877.1 - 0.014 15.4 0.2 0.14 12.2 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain UQ_con PF00179.21 GAK62878.1 - 3.5e-52 175.5 0.0 4e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAK62878.1 - 6.2e-05 22.7 0.0 7.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAK62878.1 - 0.0007 19.4 0.0 0.0009 19.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 GAK62878.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Herpes_gE PF02480.11 GAK62880.1 - 0.031 12.5 0.0 0.075 11.2 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NfeD PF01957.13 GAK62880.1 - 0.094 12.8 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding EphA2_TM PF14575.1 GAK62880.1 - 0.48 10.8 0.0 0.95 9.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.5 GAK62880.1 - 0.75 9.0 2.0 1.8 7.8 1.4 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Tweety PF04906.8 GAK62880.1 - 1.6 7.0 0.1 2.2 6.5 0.1 1.1 1 0 0 1 1 1 0 Tweety TMEM154 PF15102.1 GAK62880.1 - 1.6 8.4 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Glyco_tran_28_C PF04101.11 GAK62881.1 - 1e-20 74.0 0.0 9.9e-16 57.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain MOSC_N PF03476.11 GAK62882.1 - 4e-21 74.9 0.0 7.3e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAK62882.1 - 8.7e-09 34.9 0.0 1e-07 31.4 0.0 2.3 1 1 0 1 1 1 1 MOSC domain Csm1 PF12539.3 GAK62883.1 - 0.0021 18.5 0.0 0.0073 16.7 0.0 2.0 1 1 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 YlqD PF11068.3 GAK62883.1 - 2.6 8.0 9.0 4.9 7.1 0.9 2.5 2 0 0 2 2 2 0 YlqD protein DUF2852 PF11014.3 GAK62883.1 - 3.3 7.6 8.4 2.7 7.9 3.6 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) Ras PF00071.17 GAK62884.1 - 3.9e-58 195.4 0.1 4.7e-58 195.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK62884.1 - 2.6e-20 73.1 0.1 3.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK62884.1 - 4.7e-09 35.7 0.0 5.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAK62884.1 - 4.8e-07 29.4 0.0 9e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAK62884.1 - 0.0046 16.9 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK62884.1 - 0.0078 15.5 0.0 0.021 14.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 GAK62884.1 - 0.02 14.4 1.4 0.23 10.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 GAK62884.1 - 0.034 13.2 0.1 0.05 12.7 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ser_hydrolase PF06821.8 GAK62884.1 - 0.067 12.7 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase GDA1_CD39 PF01150.12 GAK62885.1 - 4.1e-99 332.0 0.0 6e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-CCCH PF00642.19 GAK62886.1 - 0.009 15.6 1.9 0.009 15.6 1.3 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 GAK62886.1 - 0.013 15.2 2.2 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Tyr-DNA_phospho PF06087.7 GAK62887.1 - 7.6e-33 113.7 0.0 1.2e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DUF4201 PF13870.1 GAK62889.1 - 0.00097 18.6 5.2 0.00097 18.6 3.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) ATG16 PF08614.6 GAK62889.1 - 0.0039 17.0 9.4 0.0039 17.0 6.5 2.9 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) DUF972 PF06156.8 GAK62889.1 - 1.1 9.5 11.0 2.9 8.2 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) SAM_decarbox PF01536.11 GAK62891.1 - 2.5e-77 259.7 0.0 9.2e-45 152.7 0.0 2.6 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase Imm5 PF14423.1 GAK62891.1 - 0.1 12.2 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm5 Nucleo_P87 PF07267.6 GAK62892.1 - 0.62 8.6 1.6 1.2 7.7 1.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pex24p PF06398.6 GAK62893.1 - 1.7e-05 23.8 8.0 2.6e-05 23.1 5.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin IF-2B PF01008.12 GAK62894.1 - 6.5e-56 189.3 0.4 2e-49 168.0 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family TFIIA PF03153.8 GAK62894.1 - 0.0034 17.3 0.6 0.0046 16.9 0.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.5 GAK62894.1 - 0.011 15.9 8.1 0.023 14.9 5.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 GAK62894.1 - 0.028 14.0 6.0 0.05 13.2 4.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 GAK62894.1 - 0.042 14.1 7.7 0.077 13.3 5.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Serglycin PF04360.7 GAK62894.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.0 2 0 0 2 2 1 0 Serglycin CDC45 PF02724.9 GAK62894.1 - 0.13 10.2 4.3 0.17 9.8 3.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 GAK62894.1 - 0.35 10.6 4.0 0.6 9.8 2.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3245 PF11595.3 GAK62894.1 - 0.43 10.8 6.6 0.85 9.8 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF2457 PF10446.4 GAK62894.1 - 0.93 8.1 17.2 1.5 7.4 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 GAK62894.1 - 1.4 8.3 12.0 2.8 7.4 8.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 GAK62894.1 - 2.5 7.2 12.0 3.6 6.7 8.3 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 GAK62894.1 - 4.5 6.8 13.2 7.9 6.1 9.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.3 GAK62894.1 - 5.1 6.9 15.4 8.1 6.3 10.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BTV_NS2 PF04514.7 GAK62894.1 - 5.4 5.7 6.4 8.2 5.1 4.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TRAP_alpha PF03896.11 GAK62894.1 - 6 5.7 6.7 8.7 5.2 4.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DASH_Ask1 PF08655.5 GAK62895.1 - 2.7e-28 97.5 0.1 5e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 CBS PF00571.23 GAK62896.1 - 2.9e-11 42.9 2.7 1.4e-05 24.8 0.1 4.5 5 0 0 5 5 5 2 CBS domain AIRC PF00731.15 GAK62897.1 - 1.6e-65 218.9 3.6 4e-65 217.6 2.5 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 GAK62897.1 - 2.7e-55 186.3 0.1 5e-55 185.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 GAK62897.1 - 3.6e-13 49.6 0.1 8e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAK62897.1 - 7.7e-05 22.1 0.0 0.00056 19.3 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.13 GAK62897.1 - 0.0052 16.4 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 GAK62897.1 - 0.02 15.0 1.4 8.3 6.6 0.0 3.1 2 1 1 3 3 3 0 CoA binding domain 2-Hacid_dh_C PF02826.14 GAK62897.1 - 0.037 13.1 0.1 0.11 11.6 0.1 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TIM PF00121.13 GAK62897.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Triosephosphate isomerase DSPc PF00782.15 GAK62898.1 - 2.1e-25 88.8 0.0 2.3e-18 66.0 0.0 3.3 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAK62898.1 - 0.00022 20.6 0.0 0.0049 16.2 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF2924 PF11149.3 GAK62898.1 - 0.012 15.6 0.1 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) RRM_1 PF00076.17 GAK62899.1 - 1.7e-16 59.5 0.0 2.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK62899.1 - 2.7e-10 40.0 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK62899.1 - 2.5e-06 27.2 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 GAK62899.1 - 2.6e-06 27.7 2.4 2.6e-06 27.7 1.6 2.7 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.6 GAK62899.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif ThiF PF00899.16 GAK62900.1 - 7e-40 135.9 0.1 1.7e-39 134.7 0.0 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 GAK62900.1 - 9e-27 92.4 0.1 3.7e-26 90.4 0.2 2.0 2 1 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 GAK62900.1 - 6.4e-22 76.6 3.2 1.1e-21 75.9 2.2 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 GAK62900.1 - 1.5e-10 41.0 0.9 4.3e-10 39.5 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 GAK62900.1 - 0.00054 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAK62900.1 - 0.0052 17.1 0.3 0.32 11.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAK62900.1 - 0.023 14.9 0.0 0.081 13.1 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding VHS PF00790.14 GAK62901.1 - 2.8e-40 137.2 0.0 9e-40 135.5 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 GAK62901.1 - 3.3e-24 84.7 0.0 8.2e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 GAT domain FHA PF00498.21 GAK62902.1 - 0.0018 18.3 0.1 0.0067 16.5 0.0 2.0 1 1 0 1 1 1 1 FHA domain DUF2372 PF10178.4 GAK62903.1 - 0.00069 19.7 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Citrate_synt PF00285.16 GAK62904.1 - 3.7e-17 62.1 0.1 4.1e-15 55.3 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 GAK62904.1 - 8e-15 54.7 0.1 1.5e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 GAK62904.1 - 2.4e-12 47.2 0.0 7.4e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 GAK62904.1 - 1.5e-07 30.9 0.0 2.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 GAK62904.1 - 1.8e-05 24.3 0.0 6.1e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 GAK62904.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain NAD_binding_10 PF13460.1 GAK62905.1 - 1.4e-09 38.2 0.2 2.3e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAK62905.1 - 0.00034 20.1 0.1 0.0017 17.8 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAK62905.1 - 0.0038 17.5 0.0 0.0097 16.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Germane PF10646.4 GAK62905.1 - 0.13 12.4 0.7 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Sporulation and spore germination Asparaginase PF00710.15 GAK62906.1 - 6.4e-147 488.4 0.0 8.4e-147 488.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 GAK62906.1 - 2.7e-12 46.8 0.1 6.3e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAK62906.1 - 7.3e-12 44.4 1.1 4.1e-05 23.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 GAK62906.1 - 2.7e-06 27.0 0.1 0.13 12.5 0.1 3.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAK62906.1 - 1.1e-05 25.8 0.1 5.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAK62906.1 - 0.00042 20.4 0.4 0.0095 16.1 0.0 3.4 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Pex14_N PF04695.8 GAK62906.1 - 0.026 14.5 1.1 0.05 13.6 0.0 2.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1744 PF08490.7 GAK62907.1 - 2.2e-118 395.3 0.0 3.4e-118 394.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 GAK62907.1 - 2.3e-66 223.8 0.0 4.2e-66 223.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 GAK62907.1 - 6.9e-23 81.1 0.2 5.5e-22 78.1 0.2 2.1 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 GAK62907.1 - 1.5e-10 40.9 0.0 5.3e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 GAK62907.1 - 3.3e-05 23.7 0.0 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily Glycogen_syn PF05693.8 GAK62908.1 - 0 1104.2 0.0 0 1103.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 GAK62908.1 - 2.2e-08 33.6 0.0 3.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 GAK62908.1 - 6.6e-08 32.3 0.3 4.7e-07 29.5 0.2 2.2 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 GAK62908.1 - 8.5e-07 29.2 0.3 1.6e-06 28.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Dala_Dala_lig_C PF07478.8 GAK62908.1 - 0.18 11.1 0.0 0.5 9.7 0.0 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus DBR1 PF05011.8 GAK62910.1 - 1.6e-20 73.4 0.0 6.9e-19 68.1 0.0 2.3 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 GAK62910.1 - 1.9e-06 27.4 0.1 3.4e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAK62910.1 - 2e-05 24.4 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RA PF00788.18 GAK62911.1 - 3.7e-14 52.9 0.0 4.4e-11 43.1 0.0 2.8 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 GAK62911.1 - 1.4e-07 30.7 0.0 3.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAK62911.1 - 0.00099 18.6 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain La PF05383.12 GAK62912.1 - 8.1e-17 60.7 0.0 1.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 La domain Thioredoxin PF00085.15 GAK62913.1 - 1.9e-21 75.7 0.0 2.3e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAK62913.1 - 0.00039 20.5 0.0 0.0017 18.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 GAK62913.1 - 0.013 15.4 0.0 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.1 GAK62913.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like 6PF2K PF01591.13 GAK62914.1 - 1.4e-60 204.1 0.0 1.9e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAK62914.1 - 3.1e-22 79.3 0.0 5.9e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 GAK62914.1 - 0.0043 17.8 0.5 0.027 15.2 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 GAK62914.1 - 0.051 13.4 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2361 PF10153.4 GAK62915.1 - 6.6e-21 74.6 9.1 6.6e-21 74.6 6.3 2.9 2 2 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF3336 PF11815.3 GAK62916.1 - 1.8e-41 141.0 1.4 3.2e-41 140.2 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAK62916.1 - 3.5e-20 72.8 0.6 3.1e-19 69.7 0.0 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase Pro_isomerase PF00160.16 GAK62917.1 - 2.2e-43 148.1 0.3 3.5e-43 147.4 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_60s PF00428.14 GAK62917.1 - 0.033 14.5 3.5 0.073 13.4 2.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein E1-E2_ATPase PF00122.15 GAK62918.1 - 2e-37 128.4 0.1 5.8e-37 126.9 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAK62918.1 - 2.2e-29 103.4 0.2 2.2e-28 100.1 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAK62918.1 - 4.3e-19 68.4 5.9 2.9e-06 27.3 0.0 4.9 4 1 0 4 4 4 3 Heavy-metal-associated domain HAD PF12710.2 GAK62918.1 - 2.9e-14 53.6 0.0 2.7e-13 50.5 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAK62918.1 - 0.0032 17.1 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DPBB_1 PF03330.13 GAK62920.1 - 1.2e-05 25.2 0.1 8.2e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 GAK62920.1 - 0.0073 15.9 0.1 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 Barwin family AICARFT_IMPCHas PF01808.13 GAK62921.1 - 1.3e-110 369.3 0.2 1.9e-110 368.8 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 GAK62921.1 - 1.9e-22 78.9 0.0 5.9e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 MGS-like domain Phage_int_SAM_1 PF02899.12 GAK62921.1 - 0.067 13.3 0.3 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FAD-oxidase_C PF02913.14 GAK62922.1 - 5.6e-54 183.0 0.0 9.7e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAK62922.1 - 6e-33 113.2 0.0 1.1e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DUF3918 PF13056.1 GAK62922.1 - 0.034 13.4 0.5 0.07 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Polysacc_synt_4 PF04669.8 GAK62923.1 - 1.8e-27 95.9 3.3 1.1e-26 93.4 2.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Acyl-CoA_dh_1 PF00441.19 GAK62924.1 - 4.5e-51 172.8 2.5 8.4e-51 172.0 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAK62924.1 - 9.8e-26 90.5 0.2 2.6e-25 89.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAK62924.1 - 1.8e-23 81.7 0.3 3.8e-23 80.7 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAK62924.1 - 3.7e-19 69.3 2.8 3.7e-19 69.3 1.9 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 GAK62924.1 - 2.5e-06 27.0 0.6 1.1e-05 25.0 0.4 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal OrfB_Zn_ribbon PF07282.6 GAK62926.1 - 1.1e-08 34.5 0.0 1.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain GATA PF00320.22 GAK62928.1 - 2.5e-31 106.7 18.8 1.3e-15 56.4 2.9 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 GAK62928.1 - 1.3e-05 24.3 5.6 0.041 13.2 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 GAK62928.1 - 0.0091 15.4 6.8 0.83 9.2 0.3 2.5 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 GAK62928.1 - 0.029 14.3 1.6 3.6 7.6 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain ArfGap PF01412.13 GAK62928.1 - 0.14 11.8 4.6 3.9 7.2 0.2 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zinc_ribbon_4 PF13717.1 GAK62928.1 - 0.26 10.9 2.0 8.9 6.0 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 GAK62928.1 - 0.29 10.7 1.8 7.9 6.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 GAK62928.1 - 0.49 9.9 12.1 0.54 9.8 0.4 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Auto_anti-p27 PF06677.7 GAK62928.1 - 1.5 8.6 3.5 25 4.7 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.12 GAK62928.1 - 7.7 6.2 5.3 11 5.6 0.7 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 CPSase_L_D2 PF02786.12 GAK62929.1 - 5.7e-82 274.0 0.1 9.1e-82 273.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 GAK62929.1 - 2.2e-67 226.3 0.0 3.8e-67 225.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 GAK62929.1 - 6.2e-36 122.8 0.0 2.5e-35 120.9 0.0 2.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 GAK62929.1 - 5.5e-30 104.7 0.0 9.4e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 GAK62929.1 - 2e-29 101.7 0.0 4.4e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 GAK62929.1 - 3.2e-20 72.6 0.1 5.7e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAK62929.1 - 3.3e-16 58.9 0.0 8.3e-16 57.6 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 GAK62929.1 - 1.5e-15 56.5 1.0 3e-15 55.5 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 GAK62929.1 - 1.7e-14 53.2 0.1 6.7e-06 25.6 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 GAK62929.1 - 2e-09 37.1 0.0 3.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 GAK62929.1 - 6.8e-08 32.1 0.0 0.004 16.5 0.0 2.4 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 GAK62929.1 - 1.5e-07 30.8 0.0 3.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAK62929.1 - 3.3e-06 26.7 0.0 1.4e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAK62929.1 - 3.1e-05 23.9 0.0 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 GAK62929.1 - 0.00045 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 GAK62929.1 - 0.0016 18.7 0.1 1 9.7 0.0 2.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 GAK62929.1 - 0.0064 15.6 0.1 0.078 12.1 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 GAK62929.1 - 0.014 14.5 0.6 0.034 13.3 0.1 1.7 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) MMS22L_C PF14911.1 GAK62930.1 - 0.17 10.9 0.1 0.4 9.6 0.0 1.5 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal Ribosomal_S13 PF00416.17 GAK62931.1 - 1.3e-39 134.9 1.4 1.5e-39 134.6 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 GAK62931.1 - 0.0027 16.3 0.0 0.0037 15.8 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 GAK62931.1 - 0.078 13.0 0.2 0.21 11.6 0.0 1.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif Mito_carr PF00153.22 GAK62932.1 - 3.7e-71 234.9 5.3 1.4e-23 82.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.1 GAK62932.1 - 0.062 12.6 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Clat_adaptor_s PF01217.15 GAK62933.1 - 5.7e-49 165.4 0.1 9.5e-36 122.6 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain SHR3_chaperone PF08229.6 GAK62934.1 - 5.1e-38 130.0 1.3 1.1e-37 128.8 0.9 1.6 1 1 0 1 1 1 1 ER membrane protein SH3 Neurensin PF14927.1 GAK62934.1 - 0.23 10.8 2.6 1.1 8.6 0.2 2.3 1 1 1 2 2 2 0 Neurensin AAA PF00004.24 GAK62935.1 - 4.2e-97 321.4 0.0 3e-47 160.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 GAK62935.1 - 3.2e-20 71.8 0.3 1.5e-19 69.7 0.0 2.3 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 GAK62935.1 - 3.9e-14 52.2 0.1 6.2e-06 25.4 0.0 3.2 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 GAK62935.1 - 8.4e-13 48.4 0.0 3.4e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAK62935.1 - 1.6e-12 47.6 0.0 2.7e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAK62935.1 - 1e-11 44.7 0.4 4.1e-06 26.5 0.0 3.6 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAK62935.1 - 2.4e-11 44.4 0.0 0.00055 20.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAK62935.1 - 3.7e-11 43.2 0.2 0.0024 18.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 GAK62935.1 - 7.1e-11 41.5 0.0 1.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 GAK62935.1 - 1.6e-10 41.2 0.0 0.0013 18.7 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 GAK62935.1 - 2.9e-09 36.1 0.1 0.0011 17.8 0.0 2.5 2 1 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 GAK62935.1 - 1.4e-08 34.3 1.9 0.0078 15.6 0.0 3.7 2 2 1 3 3 3 2 AAA domain Zeta_toxin PF06414.7 GAK62935.1 - 5.8e-08 32.0 0.0 0.0084 15.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 GAK62935.1 - 6.2e-08 32.2 0.0 0.004 16.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 GAK62935.1 - 9.3e-08 31.7 1.5 0.0076 15.9 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain AAA_14 PF13173.1 GAK62935.1 - 1.4e-07 31.4 0.0 0.0036 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 GAK62935.1 - 1.7e-07 30.6 0.3 0.012 14.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAK62935.1 - 5e-07 29.8 0.0 0.016 15.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 GAK62935.1 - 6.7e-07 28.6 0.4 0.43 9.6 0.0 3.5 2 1 1 3 3 3 2 KaiC Parvo_NS1 PF01057.12 GAK62935.1 - 2.8e-06 26.4 0.1 0.01 14.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 GAK62935.1 - 4.2e-06 27.1 0.0 0.035 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 GAK62935.1 - 4.6e-06 26.3 0.1 0.12 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 GAK62935.1 - 6.1e-06 26.1 0.0 0.005 16.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 GAK62935.1 - 6.4e-06 26.2 0.2 0.1 12.5 0.0 3.0 3 1 1 4 4 2 2 AAA domain Sigma54_activat PF00158.21 GAK62935.1 - 1.3e-05 24.6 0.0 0.28 10.6 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 GAK62935.1 - 1.5e-05 24.0 0.0 0.01 14.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 GAK62935.1 - 1.7e-05 24.5 0.0 0.084 12.5 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein Vps4_C PF09336.5 GAK62935.1 - 1.8e-05 24.5 0.0 0.00013 21.7 0.0 2.5 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 GAK62935.1 - 2.9e-05 24.1 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 GAK62935.1 - 3.5e-05 23.6 0.0 3.8 7.1 0.0 3.4 2 1 1 3 3 3 0 Archaeal ATPase ABC_tran PF00005.22 GAK62935.1 - 3.7e-05 24.0 0.0 0.2 11.9 0.0 3.5 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 GAK62935.1 - 4.9e-05 22.6 0.2 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 GAK62935.1 - 0.00014 21.4 0.0 0.62 9.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAK62935.1 - 0.00015 21.4 0.1 0.52 9.9 0.0 3.4 4 0 0 4 4 3 1 NACHT domain AAA_11 PF13086.1 GAK62935.1 - 0.00028 20.5 0.0 0.43 10.0 0.0 2.5 2 1 0 2 2 2 2 AAA domain DUF2075 PF09848.4 GAK62935.1 - 0.00036 19.6 0.0 0.38 9.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 GAK62935.1 - 0.00083 18.9 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 GAK62935.1 - 0.001 18.0 0.1 0.33 9.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 GAK62935.1 - 0.0036 17.0 0.3 1.2 8.8 0.0 3.5 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 GAK62935.1 - 0.005 16.3 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 GAK62935.1 - 0.0093 14.8 0.0 0.3 9.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein KAP_NTPase PF07693.9 GAK62935.1 - 0.033 13.1 0.0 0.62 9.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain UPF0079 PF02367.12 GAK62935.1 - 0.035 13.7 0.1 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 GAK62935.1 - 0.039 13.1 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 GAK62935.1 - 0.048 13.1 0.1 12 5.2 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DEAD PF00270.24 GAK62935.1 - 0.088 12.3 0.3 27 4.1 0.0 3.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase KTI12 PF08433.5 GAK62935.1 - 0.13 11.4 0.0 7.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PIF1 PF05970.9 GAK62935.1 - 0.16 10.9 0.0 6.2 5.6 0.0 2.8 3 0 0 3 3 3 0 PIF1-like helicase CCDC14 PF15254.1 GAK62935.1 - 0.17 10.2 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 PPV_E1_C PF00519.12 GAK62935.1 - 0.46 9.0 0.1 4.4 5.7 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase TPT PF03151.11 GAK62936.1 - 1.3e-11 44.3 5.2 1.3e-11 44.3 3.6 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAK62936.1 - 1.2e-10 40.8 17.0 2e-09 36.8 11.8 2.1 1 1 0 1 1 1 1 UAA transporter family MFS_1 PF07690.11 GAK62937.1 - 2e-33 115.5 38.8 4.4e-32 111.1 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK62937.1 - 5.4e-10 38.4 27.0 2e-09 36.5 18.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAK62937.1 - 0.02 13.1 5.5 0.031 12.4 3.8 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF1459 PF07312.6 GAK62937.1 - 1.6 8.7 10.3 1.1 9.1 1.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) Orn_Arg_deC_N PF02784.11 GAK62938.1 - 9e-70 234.7 0.0 1.2e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAK62938.1 - 7.8e-30 102.9 0.0 1.3e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain FA_desaturase PF00487.19 GAK62939.1 - 4.7e-26 91.7 23.3 2.1e-25 89.6 16.1 2.0 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 GAK62939.1 - 0.00015 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF1604 PF07713.8 GAK62940.1 - 2.7e-35 120.0 2.1 6.9e-35 118.7 1.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 GAK62940.1 - 3.3e-07 29.9 0.2 9.5e-07 28.5 0.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAK62940.1 - 0.0025 17.6 0.4 0.018 14.8 0.1 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site WBS28 PF15164.1 GAK62942.1 - 0.02 13.9 0.6 0.035 13.2 0.4 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue PH PF00169.24 GAK62942.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 PH domain Aminotran_3 PF00202.16 GAK62943.1 - 5.9e-101 337.6 0.2 1e-100 336.8 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-III Fork_head PF00250.13 GAK62943.1 - 9.1e-31 105.7 0.1 2e-30 104.6 0.1 1.5 1 0 0 1 1 1 1 Fork head domain Aminotran_1_2 PF00155.16 GAK62943.1 - 0.0021 17.1 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II NAD_binding_9 PF13454.1 GAK62944.1 - 0.00015 21.5 0.0 0.00052 19.8 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAK62944.1 - 0.013 15.5 0.0 3.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK62944.1 - 0.082 11.3 0.2 0.18 10.2 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 GAK62944.1 - 0.11 12.5 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK62944.1 - 0.11 12.3 0.0 2.3 8.0 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CDP-OH_P_transf PF01066.16 GAK62945.1 - 6.4e-15 55.2 3.6 6.4e-15 55.2 2.5 3.2 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase PLA2_B PF01735.13 GAK62946.1 - 5.4e-142 473.4 1.9 7.3e-142 472.9 1.3 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 GAK62946.1 - 0.0012 18.7 1.0 0.0012 18.7 0.7 2.9 4 0 0 4 4 4 1 Patatin-like phospholipase Actin PF00022.14 GAK62947.1 - 5e-94 314.9 0.0 6.2e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Actin Pkinase PF00069.20 GAK62948.1 - 4.1e-21 75.3 0.0 6.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 GAK62948.1 - 1.2e-14 53.5 10.0 6e-11 41.7 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT PF02985.17 GAK62948.1 - 7.1e-12 44.3 4.1 0.013 15.5 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 GAK62948.1 - 6e-10 38.6 0.0 2.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.1 GAK62948.1 - 1.8e-06 28.1 0.5 0.54 10.5 0.0 4.0 2 1 1 3 3 3 2 HEAT repeats Kinase-like PF14531.1 GAK62948.1 - 0.0017 17.4 0.0 0.65 8.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Nucleoporin_N PF08801.6 GAK62948.1 - 0.011 14.5 0.0 0.022 13.4 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like Kdo PF06293.9 GAK62948.1 - 0.14 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2435 PF10363.4 GAK62948.1 - 0.17 11.8 0.7 3.2 7.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) CNH PF00780.17 GAK62949.1 - 2.2e-66 224.1 0.0 3.2e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 GAK62949.1 - 2.5e-30 105.6 0.0 4.1e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 GAK62949.1 - 3.4e-07 30.2 0.0 0.00011 22.1 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain DEP PF00610.16 GAK62949.1 - 0.0048 16.6 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Acetyltransf_1 PF00583.19 GAK62950.1 - 1.4e-13 50.6 0.0 5.9e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK62950.1 - 1.9e-08 34.3 0.2 2.7e-07 30.6 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK62950.1 - 1.7e-05 24.4 0.1 0.0033 17.1 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 GAK62950.1 - 9.7e-05 22.4 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAK62950.1 - 0.0037 17.1 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAK62950.1 - 0.0056 16.8 0.0 0.008 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAK62950.1 - 0.023 14.5 0.1 0.32 10.8 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 GAK62950.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.1 GAK62950.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase_2 PF12681.2 GAK62950.1 - 0.14 12.7 0.0 1.1 9.9 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain SPT2 PF08243.6 GAK62951.1 - 3.7e-17 62.6 20.9 3.7e-17 62.6 14.5 5.8 4 3 2 6 6 6 1 SPT2 chromatin protein PRMT5 PF05185.11 GAK62952.1 - 3.2e-150 500.9 0.0 4.1e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 GAK62952.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAK62952.1 - 0.14 12.6 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0047 PF01894.12 GAK62953.1 - 7.3e-39 132.2 0.0 9.9e-39 131.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RhoGAP PF00620.22 GAK62954.1 - 3e-45 153.5 0.1 4.4e-45 153.0 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.19 GAK62955.1 - 6.6e-08 32.3 0.0 2.3e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 PX domain PH PF00169.24 GAK62955.1 - 6.4e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAK62955.1 - 0.0078 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CS PF04969.11 GAK62956.1 - 5.7e-08 33.1 0.0 1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 CS domain CRC_subunit PF08624.5 GAK62958.1 - 1.4e-45 154.6 0.1 4.2e-45 153.0 0.0 1.8 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Zn_clus PF00172.13 GAK62960.1 - 2.1e-09 37.1 7.7 4.2e-09 36.1 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 GAK62963.1 - 9.4e-22 76.9 0.0 1.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK62963.1 - 3e-09 36.5 0.0 7.8e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAK62963.1 - 2.2e-05 25.3 0.3 7.6e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAK62963.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 GAK62963.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 GAK62963.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XRN_N PF03159.13 GAK62964.1 - 3.6e-103 344.0 0.0 6.3e-103 343.2 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Lon_C PF05362.8 GAK62965.1 - 1.4e-66 223.7 0.1 2.9e-66 222.6 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 GAK62965.1 - 3.5e-34 118.2 0.0 1e-33 116.7 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 GAK62965.1 - 3.6e-21 75.7 0.0 1.1e-20 74.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 GAK62965.1 - 4.9e-07 29.2 0.0 1.6e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 GAK62965.1 - 3.3e-06 26.8 0.0 7.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAK62965.1 - 1.2e-05 25.4 0.2 0.00044 20.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 GAK62965.1 - 1.4e-05 25.1 0.0 3.5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.6 GAK62965.1 - 3.4e-05 22.7 0.0 5.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 GAK62965.1 - 0.0011 19.0 0.0 0.032 14.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK62965.1 - 0.0011 19.7 0.0 0.0039 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAK62965.1 - 0.0023 17.8 0.0 0.0065 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAK62965.1 - 0.0063 15.9 0.3 0.054 12.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAK62965.1 - 0.0079 15.2 0.0 0.039 12.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 GAK62965.1 - 0.01 16.1 0.0 0.01 16.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 GAK62965.1 - 0.039 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 GAK62965.1 - 0.04 13.1 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SKI PF01202.17 GAK62965.1 - 0.052 13.4 0.1 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.12 GAK62965.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 GAK62965.1 - 0.1 12.9 0.9 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 GAK62965.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 GAK62965.1 - 0.4 9.3 4.8 0.72 8.4 0.1 2.6 3 0 0 3 3 3 0 TIP49 C-terminus GlutR_dimer PF00745.15 GAK62966.1 - 0.11 12.5 0.5 0.14 12.0 0.3 1.3 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain SLD3 PF08639.5 GAK62966.1 - 1.2 7.6 9.9 1.3 7.5 6.8 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Ribosomal_S16 PF00886.14 GAK62967.1 - 5.6e-29 99.6 0.3 1.2e-28 98.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S16 CMAS PF02353.15 GAK62968.1 - 6.5e-61 205.7 0.3 8.6e-61 205.4 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Bax1-I PF01027.15 GAK62968.1 - 7.8e-43 146.4 27.4 7.8e-43 146.4 19.0 2.2 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Methyltransf_23 PF13489.1 GAK62968.1 - 9.3e-13 48.1 0.0 4.8e-11 42.6 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK62968.1 - 2.7e-10 40.6 0.0 1.6e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK62968.1 - 3.7e-06 26.6 0.0 7.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK62968.1 - 1.7e-05 24.8 0.2 0.0001 22.2 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK62968.1 - 4.2e-05 24.0 0.2 0.00021 21.8 0.0 2.4 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK62968.1 - 4.5e-05 23.8 0.0 0.00019 21.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 GAK62968.1 - 0.00014 21.2 0.0 0.00067 19.0 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 GAK62968.1 - 0.00022 21.5 0.0 0.00081 19.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK62968.1 - 0.0023 17.3 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 GAK62968.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 GAK62968.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 2-Hacid_dh_C PF02826.14 GAK62969.1 - 6.1e-59 198.1 0.0 8.8e-59 197.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAK62969.1 - 1.9e-20 72.7 0.1 2.1e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAK62969.1 - 1.5e-07 31.4 0.1 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAK62969.1 - 2.8e-05 24.4 0.0 8.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 GAK62969.1 - 0.00077 18.8 0.2 0.0027 17.0 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 GAK62969.1 - 0.01 15.7 0.1 0.054 13.4 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.1 GAK62969.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding PGA2 PF07543.7 GAK62970.1 - 0.016 15.0 5.4 0.034 13.9 3.8 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 PBP1_TM PF14812.1 GAK62970.1 - 3.3 8.0 7.7 7.6 6.9 5.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF159 PF02586.9 GAK62971.1 - 5.4e-52 176.3 0.0 8.3e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 TPR_MLP1_2 PF07926.7 GAK62972.1 - 1.1e-22 80.1 17.8 1.1e-22 80.1 12.3 17.1 7 7 8 15 15 15 8 TPR/MLP1/MLP2-like protein GRASP55_65 PF04495.9 GAK62973.1 - 9.8e-68 226.4 0.0 2.4e-55 186.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 GAK62973.1 - 0.02 14.7 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.19 GAK62973.1 - 0.04 14.1 0.0 8 6.7 0.0 2.4 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) PYC_OADA PF02436.13 GAK62974.1 - 0.038 13.4 0.8 0.089 12.2 0.2 1.8 1 1 1 2 2 2 0 Conserved carboxylase domain IncA PF04156.9 GAK62974.1 - 0.17 11.4 8.3 0.023 14.3 1.8 2.4 3 0 0 3 3 3 0 IncA protein RdRP PF05183.7 GAK62975.1 - 7.4e-104 348.5 0.0 4.4e-103 345.9 0.0 1.9 1 1 0 1 1 1 1 RNA dependent RNA polymerase SCP2 PF02036.12 GAK62975.1 - 1.8e-09 37.7 0.0 5.4e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 GAK62975.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Pkinase PF00069.20 GAK62976.1 - 1.4e-35 122.6 0.0 7.6e-35 120.3 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK62976.1 - 8.9e-11 41.3 0.0 4.8e-10 38.9 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK62976.1 - 5.7e-05 22.2 0.0 9.1e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK62976.1 - 0.0054 16.4 0.8 0.017 14.8 0.3 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Aminotran_3 PF00202.16 GAK62977.1 - 1e-82 277.6 0.0 1.3e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAK62977.1 - 0.13 11.2 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II ThiF PF00899.16 GAK62978.1 - 3.6e-10 39.8 0.0 6.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family Peptidase_M6 PF05547.6 GAK62979.1 - 0.13 10.2 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 RRN7 PF11781.3 GAK62980.1 - 6e-06 25.6 0.2 1.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Auto_anti-p27 PF06677.7 GAK62980.1 - 0.046 13.4 0.9 0.094 12.4 0.6 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-DHHC PF01529.15 GAK62981.1 - 1.2e-40 138.6 1.4 1.2e-40 138.6 1.0 2.2 1 1 1 2 2 2 2 DHHC palmitoyltransferase AAA_23 PF13476.1 GAK62982.1 - 5.9e-26 92.0 0.2 5.9e-26 92.0 0.1 8.2 1 1 1 3 3 1 1 AAA domain AAA_21 PF13304.1 GAK62982.1 - 1.2e-12 48.4 5.6 6e-08 33.0 0.3 3.1 3 0 0 3 3 3 2 AAA domain AAA_13 PF13166.1 GAK62982.1 - 1.3e-11 43.7 124.4 0.00011 20.8 0.0 6.9 2 1 4 6 6 6 4 AAA domain SbcCD_C PF13558.1 GAK62982.1 - 1.1e-10 41.2 0.0 3.9e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Myosin_tail_1 PF01576.14 GAK62982.1 - 2e-07 29.1 67.7 2e-07 29.1 46.9 2.1 2 0 0 2 2 1 1 Myosin tail SMC_N PF02463.14 GAK62982.1 - 2.8e-07 29.9 0.0 2.8e-07 29.9 0.0 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 GAK62982.1 - 6.1e-06 25.5 46.0 0.0027 16.8 8.8 4.4 3 1 0 3 3 3 2 AAA ATPase domain TPR_MLP1_2 PF07926.7 GAK62982.1 - 0.0011 18.6 14.6 0.0011 18.6 10.1 9.5 5 4 3 8 8 6 2 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 GAK62982.1 - 0.0033 17.2 18.9 0.0033 17.2 13.1 8.9 3 3 2 7 7 6 2 Tropomyosin like AAA_29 PF13555.1 GAK62982.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Filament PF00038.16 GAK62982.1 - 0.69 9.3 123.4 0.013 14.9 26.2 5.3 3 2 1 5 5 5 0 Intermediate filament protein Cullin PF00888.17 GAK62984.1 - 6.9e-188 625.8 1.6 9e-188 625.4 1.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAK62984.1 - 8.1e-28 96.0 4.5 2.6e-27 94.4 1.5 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain GntR PF00392.16 GAK62984.1 - 0.014 14.7 0.1 0.35 10.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.1 GAK62984.1 - 0.027 14.7 1.6 4.2 7.7 0.0 3.7 4 0 0 4 4 4 0 Winged helix DNA-binding domain Penicillinase_R PF03965.11 GAK62984.1 - 0.082 12.9 10.6 3.7 7.6 0.1 5.3 4 2 2 6 6 6 0 Penicillinase repressor Ubie_methyltran PF01209.13 GAK62985.1 - 2.8e-73 245.8 0.2 2.9e-38 131.2 0.0 2.6 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 GAK62985.1 - 7.7e-12 45.5 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK62985.1 - 2.4e-11 43.4 0.0 2.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 GAK62985.1 - 2.1e-10 40.5 0.0 3.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK62985.1 - 2.9e-10 40.4 0.0 1.3e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAK62985.1 - 9.6e-08 32.5 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK62985.1 - 7.7e-07 29.4 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK62985.1 - 6e-06 26.2 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 GAK62985.1 - 0.0029 17.2 0.0 0.014 15.0 0.0 2.1 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_28 PF02636.12 GAK62985.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 GAK62985.1 - 0.1 11.9 0.0 0.97 8.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain TFIIA PF03153.8 GAK62986.1 - 5.3e-05 23.2 23.2 5.3e-05 23.2 16.1 8.1 7 1 1 8 8 8 1 Transcription factor IIA, alpha/beta subunit GP41 PF00517.12 GAK62986.1 - 3.8 7.0 0.1 5.7 6.4 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Thiolase_N PF00108.18 GAK62987.1 - 8.9e-77 257.6 0.2 1.9e-76 256.5 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAK62987.1 - 1.4e-45 153.6 0.4 2.6e-45 152.8 0.3 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAK62987.1 - 8.9e-05 22.0 0.6 0.00089 18.8 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 GAK62987.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal BRCA-2_helical PF09169.5 GAK62987.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 BRCA2, helical ACP_syn_III PF08545.5 GAK62987.1 - 0.036 13.7 2.2 0.12 12.0 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4358 PF14270.1 GAK62987.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) DUF2093 PF09866.4 GAK62987.1 - 0.12 11.5 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Sas10 PF09368.5 GAK62988.1 - 4.2e-27 94.1 3.3 4.2e-27 94.1 2.3 2.8 3 1 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 GAK62988.1 - 2.7e-09 37.1 0.1 7.7e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ras_bdg_2 PF14847.1 GAK62988.1 - 0.35 10.7 3.9 1.3 9.0 0.0 3.4 4 0 0 4 4 4 0 Ras-binding domain of Byr2 Fcf2 PF08698.6 GAK62989.1 - 1.4e-18 66.7 0.4 4.7e-16 58.6 0.1 3.1 3 0 0 3 3 3 2 Fcf2 pre-rRNA processing EPL1 PF10513.4 GAK62991.1 - 2.2e-36 125.5 0.0 2.2e-36 125.5 0.0 7.7 2 1 2 4 4 4 1 Enhancer of polycomb-like CK_II_beta PF01214.13 GAK62992.1 - 2.9e-81 271.4 0.0 3.5e-81 271.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pho88 PF10032.4 GAK62993.1 - 6e-72 240.9 0.0 7.8e-72 240.5 0.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Tom22 PF04281.8 GAK62994.1 - 2.1e-49 166.5 1.2 2.4e-49 166.3 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Sigma70_ner PF04546.8 GAK62994.1 - 0.19 11.2 3.5 0.31 10.6 2.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Arv1 PF04161.8 GAK62995.1 - 3.9e-14 53.0 0.0 1.2e-13 51.4 0.0 1.8 1 1 0 1 1 1 1 Arv1-like family VWA_2 PF13519.1 GAK62996.1 - 1.3e-10 41.6 0.0 3.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAK62996.1 - 8.3e-09 35.4 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 GAK62996.1 - 0.0038 16.3 0.0 0.0066 15.4 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Troponin PF00992.15 GAK62996.1 - 0.017 15.2 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Troponin Integrin_beta PF00362.13 GAK62996.1 - 0.14 10.9 0.0 0.47 9.2 0.0 1.7 1 1 0 1 1 1 0 Integrin, beta chain CoatB PF10389.4 GAK62996.1 - 0.27 11.1 1.1 0.64 9.9 0.8 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B HA2 PF04408.18 GAK62997.1 - 6.5e-30 103.1 0.1 1.3e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAK62997.1 - 3.1e-24 85.0 0.1 8.6e-24 83.5 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAK62997.1 - 1.6e-11 43.9 0.0 3.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK62997.1 - 2.7e-08 33.5 0.1 5.4e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAK62997.1 - 2e-06 27.9 0.0 4.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 GAK62997.1 - 0.00069 19.4 0.2 0.014 15.2 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Myosin_head PF00063.16 GAK62997.1 - 0.0058 14.7 0.0 0.0095 14.0 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Flavi_DEAD PF07652.9 GAK62997.1 - 0.0088 15.8 0.5 0.024 14.4 0.3 1.8 1 1 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.1 GAK62997.1 - 0.025 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 GAK62997.1 - 0.041 13.3 0.6 0.25 10.7 0.4 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.11 GAK62997.1 - 0.058 12.6 0.0 0.38 9.9 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein T2SE PF00437.15 GAK62997.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 GAK62997.1 - 0.15 12.3 0.0 0.5 10.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter 3HCDH_N PF02737.13 GAK62998.1 - 1.4e-52 177.9 1.6 2.3e-52 177.2 1.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAK62998.1 - 3.8e-31 107.3 0.0 9.4e-31 106.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 GAK62998.1 - 6.8e-05 22.6 1.1 0.00017 21.3 0.7 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 GAK62998.1 - 0.002 17.5 1.3 0.0086 15.4 0.6 2.2 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 GAK62998.1 - 0.012 15.4 3.6 0.044 13.6 1.6 2.5 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1188 PF06690.6 GAK62998.1 - 0.023 13.8 0.0 0.057 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) F420_oxidored PF03807.12 GAK62998.1 - 0.031 14.7 4.2 0.67 10.4 2.9 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 GAK62998.1 - 0.032 13.1 1.7 0.054 12.4 1.2 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase DUF1104 PF06518.6 GAK62998.1 - 0.04 14.0 0.1 3.1 7.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) ThiF PF00899.16 GAK62998.1 - 0.085 12.6 0.8 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 ThiF family DapB_N PF01113.15 GAK62998.1 - 0.28 11.1 4.8 1.9 8.4 2.0 2.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RNA_pol_3_Rpc31 PF11705.3 GAK62999.1 - 0.013 15.4 5.1 0.017 15.0 3.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Spt5_N PF11942.3 GAK62999.1 - 0.042 14.4 4.2 0.042 14.4 2.9 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FLO_LFY PF01698.11 GAK62999.1 - 0.066 12.0 5.3 0.076 11.8 3.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein BTV_NS2 PF04514.7 GAK62999.1 - 0.19 10.5 4.9 0.22 10.3 3.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SR-25 PF10500.4 GAK62999.1 - 0.43 10.0 16.3 0.56 9.6 11.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-B_dimeris PF09026.5 GAK62999.1 - 0.8 9.9 6.2 1.4 9.1 4.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 GAK62999.1 - 1.8 6.4 6.3 1.9 6.4 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3484 PF11983.3 GAK62999.1 - 6.4 7.6 7.1 11 6.8 3.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3484) Prefoldin PF02996.12 GAK63000.1 - 1.4e-27 95.7 3.7 1.8e-27 95.3 2.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit COG2 PF06148.6 GAK63000.1 - 0.0044 16.8 3.0 0.41 10.5 0.6 2.1 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 HN PF00423.14 GAK63000.1 - 0.0074 14.6 1.2 0.0085 14.4 0.8 1.0 1 0 0 1 1 1 1 Haemagglutinin-neuraminidase Rbsn PF11464.3 GAK63000.1 - 0.013 14.9 2.3 0.013 14.9 1.6 2.2 3 0 0 3 3 3 0 Rabenosyn Rab binding domain Baculo_PEP_C PF04513.7 GAK63000.1 - 0.015 15.1 4.1 0.33 10.7 0.6 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAK63000.1 - 0.031 14.0 3.1 0.82 9.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) P2_Phage_GpR PF06891.6 GAK63000.1 - 0.036 13.8 1.8 4.4 7.1 0.4 2.1 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) XkdW PF09636.5 GAK63000.1 - 0.043 13.6 2.7 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 XkdW protein DUF972 PF06156.8 GAK63000.1 - 0.065 13.5 7.4 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) COG5 PF10392.4 GAK63000.1 - 0.067 13.1 2.0 1.1 9.2 0.4 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 AIP3 PF03915.8 GAK63000.1 - 0.078 11.8 4.9 0.14 11.0 3.4 1.4 1 1 0 1 1 1 0 Actin interacting protein 3 GAS PF13851.1 GAK63000.1 - 0.24 10.5 7.2 3.3 6.8 2.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0449 PF15136.1 GAK63000.1 - 0.29 11.3 3.2 5.9 7.1 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Bacillus_HBL PF05791.6 GAK63000.1 - 0.75 9.1 6.4 0.42 9.9 1.5 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FliJ PF02050.11 GAK63000.1 - 0.94 9.5 10.9 1.4 8.9 5.5 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein TMPIT PF07851.8 GAK63000.1 - 1.2 8.1 5.8 7.6 5.4 2.0 2.0 2 0 0 2 2 2 0 TMPIT-like protein SlyX PF04102.7 GAK63000.1 - 1.2 9.5 10.3 0.88 9.9 4.1 2.2 2 0 0 2 2 2 0 SlyX Rootletin PF15035.1 GAK63000.1 - 1.4 8.8 10.4 15 5.5 0.1 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.5 GAK63000.1 - 1.6 8.8 8.3 8.7 6.4 2.9 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 GAK63000.1 - 1.8 8.5 4.4 23 4.9 1.3 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-Q PF13094.1 GAK63000.1 - 2.3 8.2 12.5 1.6 8.7 0.3 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2508 PF10704.4 GAK63000.1 - 6.4 7.0 7.7 2.2 8.5 2.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) IncA PF04156.9 GAK63000.1 - 9.3 5.7 12.9 7.2e+02 -0.4 9.0 2.1 1 1 0 1 1 1 0 IncA protein PPR_3 PF13812.1 GAK63001.1 - 0.011 15.9 1.2 3.6 8.0 0.0 3.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain ATP-synt_DE_N PF02823.11 GAK63002.1 - 2.5e-18 65.6 0.1 3.5e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF3373 PF11853.3 GAK63002.1 - 0.15 10.5 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) CRISPR_Cse2 PF09485.5 GAK63004.1 - 0.03 14.3 0.6 0.042 13.9 0.4 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) ABC_membrane_2 PF06472.10 GAK63005.1 - 7.7e-100 333.6 2.0 1e-99 333.2 1.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAK63005.1 - 1.9e-19 70.2 0.0 3.8e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAK63005.1 - 0.00015 21.8 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 GAK63005.1 - 0.0051 17.1 0.3 0.053 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAK63005.1 - 0.019 14.2 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.10 GAK63005.1 - 0.02 13.5 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.1 GAK63005.1 - 0.025 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAK63005.1 - 0.044 13.7 0.8 0.089 12.7 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 GAK63005.1 - 0.087 12.5 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 GAK63005.1 - 0.15 10.6 0.0 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 GAK63005.1 - 0.2 10.8 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PPR_2 PF13041.1 GAK63006.1 - 9.2e-25 86.3 0.0 3.6e-08 33.2 0.0 6.7 7 1 1 8 8 8 5 PPR repeat family PPR_3 PF13812.1 GAK63006.1 - 5.3e-20 69.9 10.6 0.0011 19.1 0.1 8.9 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 GAK63006.1 - 1e-14 53.3 1.7 0.0024 17.7 0.0 6.5 7 1 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 GAK63006.1 - 7.3e-09 34.9 1.9 0.00013 21.4 0.0 5.9 6 1 0 6 6 6 1 PPR repeat Sec3_C PF09763.4 GAK63007.1 - 7.6e-195 649.0 0.0 1.1e-194 648.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 GAK63007.1 - 2.3e-25 88.2 0.1 4.3e-25 87.3 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 GAK63007.1 - 2.1e-05 23.2 0.7 2.1e-05 23.2 0.5 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family DUF500 PF04366.7 GAK63008.1 - 2.6e-42 143.2 0.3 5.3e-42 142.2 0.1 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF500) Glyco_transf_8 PF01501.15 GAK63009.1 - 1e-24 87.2 0.0 1.8e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 GAK63009.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase PI3_PI4_kinase PF00454.22 GAK63010.1 - 2.6e-51 174.3 0.0 5.7e-51 173.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 GAK63010.1 - 7.3e-28 97.5 0.2 1.5e-27 96.4 0.2 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 GAK63010.1 - 5e-26 90.7 0.0 2.8e-25 88.3 0.0 2.4 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 GAK63010.1 - 4.1e-10 38.9 0.1 9.5e-10 37.7 0.1 1.6 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 GAK63010.1 - 0.0037 16.8 1.0 0.014 15.0 0.0 2.6 3 0 0 3 3 3 1 TPR repeat PrkA PF06798.7 GAK63010.1 - 0.19 11.0 0.1 2.4 7.3 0.0 2.5 3 0 0 3 3 3 0 PrkA serine protein kinase C-terminal domain TPR_14 PF13428.1 GAK63010.1 - 0.26 12.0 0.0 0.26 12.0 0.0 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat MOZART1 PF12554.3 GAK63011.1 - 3.4e-18 64.8 0.4 4.2e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated PBP1_TM PF14812.1 GAK63012.1 - 0.012 15.8 8.4 0.12 12.7 0.2 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PEP_mutase PF13714.1 GAK63013.1 - 1.1e-40 139.3 1.5 1.3e-40 139.1 1.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAK63013.1 - 3.5e-16 58.5 0.4 4.7e-16 58.0 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family UreF PF01730.11 GAK63014.1 - 1.1e-09 38.5 1.1 3.1e-09 37.1 0.8 1.7 1 1 0 1 1 1 1 UreF Herpes_capsid PF06112.6 GAK63014.1 - 0.83 9.6 6.7 2.1 8.3 4.6 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FAM72 PF14976.1 GAK63019.1 - 2.5e-17 63.1 5.3 7.9e-17 61.4 3.7 1.7 1 1 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 GAK63019.1 - 0.14 12.2 7.8 1.2 9.2 0.0 2.6 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly OrfB_Zn_ribbon PF07282.6 GAK63019.1 - 9.1 6.0 8.3 0.5 10.0 0.1 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Oxysterol_BP PF01237.13 GAK63021.1 - 6.4e-118 393.2 0.0 8.6e-118 392.8 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 GAK63021.1 - 4.4e-17 61.9 0.0 1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAK63021.1 - 5.4e-06 26.5 0.0 2.4e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAK63021.1 - 0.037 14.2 0.1 0.16 12.2 0.0 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain Myc-LZ PF02344.10 GAK63021.1 - 0.14 11.8 3.4 0.83 9.3 0.9 2.4 2 0 0 2 2 2 0 Myc leucine zipper domain CoA_transf_3 PF02515.12 GAK63023.1 - 5.3e-27 94.3 1.5 1.9e-26 92.4 0.2 2.1 2 0 0 2 2 2 1 CoA-transferase family III IGPD PF00475.13 GAK63025.1 - 2.8e-60 202.3 0.4 5.2e-60 201.5 0.2 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PLDc_2 PF13091.1 GAK63026.1 - 1.1e-14 54.1 0.0 4.9e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAK63026.1 - 3.2e-07 29.9 2.3 0.012 15.4 0.1 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif MitMem_reg PF13012.1 GAK63027.1 - 1e-36 125.4 0.1 2.1e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 GAK63027.1 - 1.4e-28 98.9 0.0 2.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AAA_11 PF13086.1 GAK63028.1 - 1.5e-63 214.5 0.2 2.8e-63 213.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 GAK63028.1 - 1.8e-51 174.3 0.0 3.1e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAK63028.1 - 8.9e-12 44.9 1.5 6.8e-10 38.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK63028.1 - 4.1e-11 42.4 4.9 5.7e-11 42.0 0.9 2.9 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 GAK63028.1 - 5.2e-10 39.2 0.3 0.045 13.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 GAK63028.1 - 8e-05 22.0 0.0 0.0018 17.6 0.1 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 GAK63028.1 - 8.8e-05 21.6 0.4 0.014 14.3 0.1 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 GAK63028.1 - 0.0001 22.4 0.0 0.0092 16.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAK63028.1 - 0.00011 21.6 0.0 0.00028 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 GAK63028.1 - 0.00028 20.9 0.2 0.0041 17.2 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 GAK63028.1 - 0.0012 18.1 0.0 1.2 8.2 0.0 2.7 3 0 0 3 3 3 2 PhoH-like protein DEAD PF00270.24 GAK63028.1 - 0.0021 17.5 0.0 0.0083 15.6 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 GAK63028.1 - 0.0074 15.2 0.0 0.018 13.9 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 GAK63028.1 - 0.0088 16.0 3.3 0.015 15.2 1.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 GAK63028.1 - 0.011 15.8 1.4 0.032 14.4 0.3 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAK63028.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus UvrD_C PF13361.1 GAK63028.1 - 0.017 14.5 0.0 0.89 8.9 0.1 2.2 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 GAK63028.1 - 0.022 15.5 0.0 0.096 13.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 GAK63028.1 - 0.073 12.7 0.3 1.2 8.7 0.2 2.5 1 1 0 1 1 1 0 Helicase AAA_18 PF13238.1 GAK63028.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAK63028.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 GAK63028.1 - 0.17 11.4 0.5 0.68 9.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain IKI3 PF04762.7 GAK63029.1 - 3.4e-275 915.4 0.0 4.3e-275 915.0 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Antimicrobial_1 PF08018.6 GAK63029.1 - 0.34 10.8 3.0 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Frog antimicrobial peptide Pkinase PF00069.20 GAK63030.1 - 5.2e-65 219.1 0.0 7.4e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63030.1 - 2.7e-34 118.4 0.0 3.7e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK63030.1 - 0.0096 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ribosomal_L14 PF00238.14 GAK63031.1 - 2.1e-44 150.1 0.9 2.3e-44 150.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e MBOAT_2 PF13813.1 GAK63032.1 - 8e-07 29.0 3.6 2.2e-06 27.6 0.3 2.7 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PPR_2 PF13041.1 GAK63034.1 - 2.2e-40 136.3 0.5 5.3e-13 48.7 0.0 8.0 7 1 1 8 8 8 4 PPR repeat family PPR PF01535.15 GAK63034.1 - 1.3e-31 106.3 2.0 0.00022 20.9 0.0 12.0 12 0 0 12 12 12 5 PPR repeat PPR_1 PF12854.2 GAK63034.1 - 1.1e-27 95.1 0.0 0.0029 17.0 0.0 7.9 7 0 0 7 7 7 6 PPR repeat PPR_3 PF13812.1 GAK63034.1 - 1.5e-26 90.3 21.2 0.00024 21.1 0.0 12.4 14 0 0 14 14 13 5 Pentatricopeptide repeat domain ECSIT PF06239.6 GAK63034.1 - 0.0005 19.0 0.0 0.066 12.0 0.0 2.5 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_2 PF07719.12 GAK63034.1 - 0.00068 19.3 1.6 1 9.4 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAK63034.1 - 0.0082 16.0 10.1 7.3 6.6 0.0 6.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAK63034.1 - 0.049 13.4 4.4 2.8 7.9 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAK63034.1 - 0.12 12.2 0.2 16 5.4 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 GAK63034.1 - 0.26 11.2 6.9 3.2 7.8 0.2 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAK63034.1 - 0.46 11.0 7.7 14 6.4 0.3 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAK63034.1 - 0.97 9.3 2.8 46 4.1 0.1 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat YEATS PF03366.11 GAK63035.1 - 5.1e-32 109.4 0.1 1.5e-31 107.9 0.0 1.7 1 1 0 1 1 1 1 YEATS family KfrA_N PF11740.3 GAK63035.1 - 0.003 18.0 0.2 0.003 18.0 0.2 2.2 3 0 0 3 3 3 1 Plasmid replication region DNA-binding N-term ATP-synt_DE PF00401.15 GAK63035.1 - 3.9 7.4 10.4 0.066 13.1 2.2 1.8 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Tyrosinase PF00264.15 GAK63036.1 - 9.3e-17 61.9 4.1 1.4e-16 61.3 2.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_7 PF03441.9 GAK63037.1 - 2.6e-62 210.5 1.7 4.2e-62 209.8 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAK63037.1 - 4.7e-24 85.0 0.0 1.4e-23 83.4 0.0 1.8 1 1 0 1 1 1 1 DNA photolyase Lyase_8 PF02278.13 GAK63037.1 - 0.06 12.7 0.1 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain RNA_pol_Rpb2_6 PF00562.23 GAK63038.1 - 1.1e-112 376.6 0.0 1.5e-112 376.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Porphobil_deam PF01379.15 GAK63038.1 - 1.3e-66 223.6 0.0 9.8e-63 210.9 0.0 2.4 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain RNA_pol_Rpb2_1 PF04563.10 GAK63038.1 - 3.2e-26 91.5 0.0 4.5e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 GAK63038.1 - 1.9e-23 82.1 0.0 1e-22 79.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 GAK63038.1 - 2.8e-23 81.4 0.0 6.6e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 GAK63038.1 - 8.6e-19 67.6 0.0 1.6e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 GAK63038.1 - 1e-16 60.9 0.1 2.6e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 Porphobil_deamC PF03900.10 GAK63038.1 - 3.4e-13 49.4 0.0 9.9e-08 31.9 0.0 2.6 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain RNA_pol_Rpb2_5 PF04567.12 GAK63038.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 WD40 PF00400.27 GAK63039.1 - 3.7e-07 29.7 0.1 0.51 10.3 0.0 5.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ArsB PF02040.10 GAK63040.1 - 1.1e-10 41.1 15.2 6e-08 32.0 1.8 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein FtsJ PF01728.14 GAK63041.1 - 1.2e-47 162.2 0.0 1.7e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pyr_redox_2 PF07992.9 GAK63043.1 - 6.8e-40 137.0 0.4 1e-39 136.4 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 GAK63043.1 - 4.7e-30 103.8 1.1 9.1e-30 102.9 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 GAK63043.1 - 4.4e-22 78.2 3.7 8.8e-19 67.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK63043.1 - 2.8e-12 47.1 0.0 7.1e-06 26.2 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK63043.1 - 5.4e-06 25.1 2.9 0.12 10.7 0.0 3.1 2 1 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 GAK63043.1 - 3.3e-05 23.1 0.1 6.5e-05 22.1 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAK63043.1 - 0.00098 18.1 0.0 0.0054 15.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAK63043.1 - 0.0052 16.7 1.3 0.017 15.1 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 GAK63043.1 - 0.012 15.9 0.1 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.12 GAK63043.1 - 0.024 13.7 0.2 0.056 12.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 GAK63043.1 - 0.057 12.3 9.9 0.33 9.7 0.2 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK63043.1 - 0.2 10.4 6.3 0.08 11.7 1.9 2.1 3 0 0 3 3 3 0 FAD binding domain FH2 PF02181.18 GAK63044.1 - 1.9e-85 287.0 8.1 2.3e-85 286.7 0.0 2.8 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 GAK63044.1 - 1.1e-29 103.1 0.1 3.9e-21 75.2 0.0 3.6 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAK63044.1 - 5.5e-21 74.8 0.7 1.5e-20 73.4 0.5 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain Glycos_transf_4 PF00953.16 GAK63044.1 - 0.38 10.5 0.0 0.7 9.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 LMWPc PF01451.16 GAK63044.1 - 0.46 10.8 3.4 0.89 9.8 1.8 1.9 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase TMF_DNA_bd PF12329.3 GAK63044.1 - 2 8.2 42.5 0.098 12.4 2.1 6.4 5 1 1 6 6 6 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 GAK63044.1 - 2.4 6.5 20.2 0.066 11.6 1.6 2.2 1 1 0 2 2 2 0 AAA domain Erp_C PF06780.6 GAK63044.1 - 3.1 7.6 9.1 0.79 9.5 0.1 3.5 3 1 1 4 4 4 0 Erp protein C-terminus MRP-S25 PF13741.1 GAK63045.1 - 3.3e-65 219.8 0.6 4.7e-65 219.3 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 GAK63045.1 - 0.00011 22.1 0.2 0.33 10.8 0.1 2.4 2 0 0 2 2 2 2 Mitochondrial ribosomal protein S23 Polysacc_deac_1 PF01522.16 GAK63046.1 - 1.5e-19 69.8 0.0 5.1e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide deacetylase Macoilin PF09726.4 GAK63046.1 - 1.3 7.2 11.8 1.7 6.8 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Catalase PF00199.14 GAK63047.1 - 6.8e-07 28.3 1.0 0.0069 15.1 0.0 2.3 2 1 0 2 2 2 2 Catalase UPF0086 PF01868.11 GAK63048.1 - 1.5e-14 53.3 0.0 4e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function UPF0086 MCPVI PF02993.9 GAK63048.1 - 0.28 11.2 4.3 0.47 10.5 2.9 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Velvet PF11754.3 GAK63049.1 - 2.7e-65 219.8 0.0 3.9e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Velvet factor COX6A PF02046.10 GAK63050.1 - 6.9e-32 109.7 0.5 7.9e-32 109.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Arm PF00514.18 GAK63051.1 - 9.7e-68 221.9 28.0 8.2e-12 44.4 0.0 11.5 10 1 1 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAK63051.1 - 5.1e-22 77.9 14.3 0.00026 21.1 0.1 7.3 2 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 GAK63051.1 - 2e-14 52.2 23.9 0.57 10.4 0.0 10.8 12 0 0 12 12 11 6 HEAT repeat HEAT_EZ PF13513.1 GAK63051.1 - 6.6e-14 51.9 14.5 0.017 15.6 0.1 8.9 7 4 2 9 9 8 5 HEAT-like repeat Adaptin_N PF01602.15 GAK63051.1 - 4.5e-11 41.7 6.1 2.2e-07 29.5 0.1 3.0 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 GAK63051.1 - 1.7e-10 40.4 5.4 9.5e-06 24.8 0.7 3.5 1 1 2 4 4 4 3 Armadillo-like KAP PF05804.7 GAK63051.1 - 5.8e-10 37.7 0.1 1.2e-09 36.7 0.0 1.3 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 GAK63051.1 - 8.9e-08 31.6 3.9 0.002 17.3 0.4 4.4 1 1 1 3 3 3 3 V-ATPase subunit H V-ATPase_H_C PF11698.3 GAK63051.1 - 0.012 15.4 2.9 12 5.8 0.0 4.4 2 1 3 5 5 5 0 V-ATPase subunit H HEAT_PBS PF03130.11 GAK63051.1 - 0.29 11.7 12.8 89 4.0 0.0 7.4 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat CTNNBL PF08216.6 GAK63051.1 - 1.8 8.1 5.3 10 5.7 0.1 4.1 5 1 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear Sigma70_r3 PF04539.11 GAK63052.1 - 0.0029 17.4 0.0 0.012 15.5 0.0 2.0 1 0 0 1 1 1 1 Sigma-70 region 3 FeoC PF09012.5 GAK63052.1 - 0.047 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator CENP-B_N PF04218.8 GAK63052.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Glyoxal_oxid_N PF07250.6 GAK63053.1 - 2.1e-35 121.9 0.0 1.4e-33 116.0 0.0 3.2 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 GAK63053.1 - 5.8e-22 77.6 0.1 1.1e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 GAK63053.1 - 9.2e-05 22.1 5.2 0.21 11.3 0.1 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Reg_prop PF07494.6 GAK63053.1 - 0.053 13.5 0.3 20 5.6 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller CD99L2 PF12301.3 GAK63053.1 - 0.17 11.5 2.4 0.37 10.4 1.7 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 Maf PF02545.9 GAK63055.1 - 2.4e-42 144.2 0.0 3.8e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein DAO PF01266.19 GAK63055.1 - 3.8e-19 68.7 0.6 4.5e-18 65.2 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK63055.1 - 0.073 12.8 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding SMK-1 PF04802.10 GAK63056.1 - 5.4e-72 241.3 0.8 1e-71 240.5 0.6 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 RRN3 PF05327.6 GAK63056.1 - 0.084 10.9 0.0 0.084 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.27 GAK63057.1 - 4.6e-67 219.6 22.5 1.7e-06 27.6 0.0 12.4 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 GAK63057.1 - 1.5e-20 73.1 0.7 2.4e-20 72.4 0.5 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 GAK63057.1 - 9.5e-10 37.2 3.1 0.13 10.3 0.0 6.5 3 2 4 7 7 7 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAK63057.1 - 3.4e-06 26.0 0.0 1.6 7.3 0.0 5.5 4 2 0 6 6 6 3 Nup133 N terminal like Glyco_transf_15 PF01793.11 GAK63059.1 - 5.9e-133 442.9 4.5 7.5e-133 442.5 3.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DIOX_N PF14226.1 GAK63061.1 - 5.3e-19 68.8 0.0 1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAK63061.1 - 4.7e-14 52.4 0.0 9e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3419 PF11899.3 GAK63062.1 - 6.7e-143 475.9 0.0 9.1e-143 475.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 GAK63062.1 - 1.1e-09 38.2 0.0 5.7e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK63062.1 - 4.3e-09 35.8 0.0 1.1e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAK63062.1 - 7.5e-09 35.3 0.0 2.1e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK63062.1 - 2e-08 34.6 0.0 5.9e-06 26.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK63062.1 - 7.4e-08 32.6 0.0 3.2e-07 30.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK63062.1 - 3.4e-07 30.6 0.0 8.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK63062.1 - 2e-06 28.3 0.0 8.3e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK63062.1 - 5.7e-05 23.1 0.0 0.0076 16.2 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAK63062.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Sugar_tr PF00083.19 GAK63065.1 - 4e-96 322.3 18.8 5.4e-55 186.7 2.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAK63065.1 - 4.8e-27 94.6 30.3 1e-26 93.5 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAK63065.1 - 0.00016 20.0 3.0 0.00029 19.1 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 GAK63065.1 - 0.052 13.6 5.6 0.14 12.2 2.8 2.5 2 0 0 2 2 2 0 Phage holin family 2 SNARE_assoc PF09335.6 GAK63066.1 - 2.8e-08 34.0 12.1 6.6e-08 32.8 5.8 2.8 2 1 0 2 2 2 1 SNARE associated Golgi protein Sld5 PF05916.6 GAK63067.1 - 8.2e-18 64.6 0.0 1.6e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein RhoGAP PF00620.22 GAK63068.1 - 3.4e-39 133.8 0.0 7e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 GAK63068.1 - 1.8e-13 50.6 0.0 7.2e-13 48.6 0.0 2.0 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 GAK63068.1 - 9.8e-12 44.8 0.0 6.1e-11 42.3 0.0 2.4 2 1 0 2 2 2 1 RasGEF N-terminal motif PH PF00169.24 GAK63068.1 - 3.1e-07 30.5 0.0 0.0073 16.4 0.0 3.1 3 0 0 3 3 3 2 PH domain PH_9 PF15410.1 GAK63068.1 - 8e-07 29.2 0.0 2.1e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain AMP-binding PF00501.23 GAK63069.1 - 5.7e-87 291.8 0.0 7.4e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK63069.1 - 8.8e-12 45.8 1.2 2.6e-11 44.3 0.8 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SnoaL PF07366.7 GAK63070.1 - 4.5e-07 29.4 0.0 9.2e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAK63070.1 - 0.00011 22.5 0.0 0.00029 21.2 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain Peptidase_S66 PF02016.10 GAK63070.1 - 0.044 12.7 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase CDC50 PF03381.10 GAK63071.1 - 2.6e-95 318.7 0.2 3.5e-95 318.3 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RabGAP-TBC PF00566.13 GAK63072.1 - 1e-24 87.2 0.0 3.1e-20 72.5 0.0 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain ATG_C PF09333.6 GAK63074.1 - 1.1e-21 76.7 0.2 3.2e-21 75.3 0.2 1.9 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 GAK63074.1 - 1.4e-11 43.9 0.0 6.4e-11 41.8 0.0 2.1 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 GAK63074.1 - 5.8e-05 22.7 0.3 0.00013 21.5 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif bZIP_C PF12498.3 GAK63074.1 - 0.0063 17.7 0.2 0.0063 17.7 0.1 3.3 3 0 0 3 3 3 1 Basic leucine-zipper C terminal Cellulase PF00150.13 GAK63075.1 - 7.4e-14 51.6 16.9 2.3e-13 49.9 11.7 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Epimerase PF01370.16 GAK63076.1 - 0.0003 20.2 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1188 PF06690.6 GAK63076.1 - 0.093 11.8 0.0 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) AAR2 PF05282.6 GAK63078.1 - 7.3e-61 206.1 0.0 9.3e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein CaATP_NAI PF12515.3 GAK63078.1 - 0.26 10.8 1.8 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Sec7 PF01369.15 GAK63079.1 - 3.7e-61 206.1 0.0 6.2e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 GAK63079.1 - 2.9e-16 59.3 1.3 2e-10 40.3 0.1 2.7 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RNase_H2-Ydr279 PF09468.5 GAK63079.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) FAD_binding_2 PF00890.19 GAK63080.1 - 9.5e-127 423.2 3.2 1.2e-126 422.9 2.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 GAK63080.1 - 1.7e-48 163.6 0.7 2.6e-48 163.1 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 GAK63080.1 - 8.7e-06 24.8 0.1 0.002 17.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 GAK63080.1 - 1e-05 24.7 0.4 0.0028 16.8 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 GAK63080.1 - 1.2e-05 24.4 1.1 0.03 13.1 1.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAK63080.1 - 0.0017 18.3 5.9 0.023 14.5 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAK63080.1 - 0.0074 15.3 0.2 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAK63080.1 - 0.049 13.6 0.9 3.8 7.5 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK63080.1 - 0.12 10.7 2.7 0.5 8.7 0.5 2.7 3 0 0 3 3 3 0 HI0933-like protein KTI12 PF08433.5 GAK63081.1 - 3.4e-58 196.9 0.0 5.8e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 GAK63081.1 - 2.1e-07 30.8 0.0 4.5e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 GAK63082.1 - 2e-46 157.6 0.0 1.6e-45 154.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK63082.1 - 1.4e-23 82.5 0.0 7.6e-23 80.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAK63082.1 - 0.00045 19.1 0.0 0.00083 18.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PAP_assoc PF03828.14 GAK63083.1 - 6.1e-21 74.1 0.0 1.4e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAK63083.1 - 1.8e-07 31.4 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4551 PF15087.1 GAK63083.1 - 2.6 6.2 6.8 4.6 5.4 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) tRNA-synt_2d PF01409.15 GAK63085.1 - 4.4e-47 160.3 0.0 6.8e-26 90.9 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 GAK63085.1 - 2.8e-24 85.0 0.1 6e-24 84.0 0.1 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Ded_cyto PF06920.8 GAK63086.1 - 3.7e-42 143.6 0.0 6.4e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAK63086.1 - 2.7e-33 115.1 0.0 8e-33 113.6 0.0 1.8 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Pkinase PF00069.20 GAK63089.1 - 4.5e-58 196.4 0.0 5.3e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63089.1 - 2.4e-19 69.4 0.0 3.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK63089.1 - 4.2e-07 29.9 0.0 4.5e-06 26.5 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAK63089.1 - 0.022 14.3 0.2 0.022 14.3 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 GAK63089.1 - 0.026 13.5 0.1 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2456 PF10445.4 GAK63090.1 - 7.6e-30 102.6 1.9 1.4e-29 101.8 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) RRM_1 PF00076.17 GAK63091.1 - 2.2e-48 161.7 0.0 6.3e-20 70.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK63091.1 - 4.7e-39 132.2 0.0 9.2e-14 51.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK63091.1 - 4.7e-23 80.8 0.0 4.2e-09 36.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAK63091.1 - 0.043 13.5 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 SNF2_N PF00176.18 GAK63094.1 - 3.1e-83 279.0 2.2 6.7e-83 277.9 1.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK63094.1 - 2e-17 62.8 0.0 1.1e-16 60.4 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 GAK63094.1 - 4.9e-17 61.4 6.8 4.9e-17 61.4 4.7 3.6 3 0 0 3 3 3 1 HSA Bromodomain PF00439.20 GAK63094.1 - 1.9e-15 56.5 0.0 5.3e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 GAK63094.1 - 9.5e-15 54.5 2.9 9.5e-15 54.5 2.0 3.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 GAK63094.1 - 3.7e-13 48.6 1.0 3.7e-13 48.6 0.7 2.0 2 0 0 2 2 2 1 QLQ RNA_pol_L_2 PF13656.1 GAK63095.1 - 2.9e-23 81.0 0.0 2.7e-22 77.9 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAK63095.1 - 6.4e-07 28.4 0.0 9.6e-06 24.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TFIIS_M PF07500.9 GAK63096.1 - 2.6e-20 72.5 0.1 3.3e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain DUF218 PF02698.12 GAK63097.1 - 1e-05 25.0 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 2 DUF218 domain Usp PF00582.21 GAK63098.1 - 2.3e-20 73.1 0.1 3.2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Toprim_4 PF13662.1 GAK63098.1 - 3.2e-05 23.8 0.1 0.00065 19.6 0.0 2.2 2 0 0 2 2 2 1 Toprim domain DUF3253 PF11625.3 GAK63098.1 - 0.096 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Phage_DsbA PF11126.3 GAK63098.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DsbA PHD PF00628.24 GAK63099.1 - 4.3e-09 35.9 7.2 6.8e-09 35.2 5.0 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 GAK63099.1 - 4.7e-09 36.4 0.0 8.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 GAK63099.1 - 0.63 9.3 2.8 1.1 8.6 2.0 1.3 1 0 0 1 1 1 0 PHD-finger EF1_GNE PF00736.14 GAK63100.1 - 2.5e-28 97.5 1.8 2.5e-28 97.5 1.2 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 GAK63100.1 - 8.3e-14 51.4 4.0 8.3e-14 51.4 2.8 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 GAK63100.1 - 0.00043 20.7 0.0 0.0009 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAK63100.1 - 0.006 16.4 0.3 0.086 12.7 0.2 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAK63100.1 - 0.035 14.0 0.2 0.11 12.5 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DNA_ligase_A_M PF01068.16 GAK63101.1 - 1.1e-08 34.6 0.0 4.7e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 GAK63101.1 - 9.2e-06 25.2 0.1 2.4e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 DNA ligase OB-like domain ORC5_C PF14630.1 GAK63102.1 - 8e-50 169.8 0.3 1.6e-48 165.5 0.2 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF3292 PF11696.3 GAK63103.1 - 3.8e-192 639.6 0.8 1.4e-110 370.0 0.2 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) Arylesterase PF01731.15 GAK63104.1 - 0.017 15.0 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Arylesterase CDC50 PF03381.10 GAK63104.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family SBBP PF06739.6 GAK63104.1 - 0.44 10.3 2.6 0.51 10.1 0.4 2.2 2 0 0 2 2 2 0 Beta-propeller repeat Trypsin_2 PF13365.1 GAK63105.1 - 1.1e-05 25.4 0.1 4.8e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain MRP-L20 PF12824.2 GAK63106.1 - 1.1e-33 116.4 3.1 3.5e-33 114.8 1.8 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.9 GAK63106.1 - 2.6e-05 24.1 0.0 0.00017 21.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK63106.1 - 0.0016 18.2 0.0 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAK63106.1 - 0.0025 17.8 0.2 0.0058 16.7 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK63106.1 - 0.011 14.7 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Malic_M PF03949.10 GAK63106.1 - 0.15 11.6 0.2 0.23 10.9 0.2 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain DUF3818 PF12825.2 GAK63107.1 - 1.4e-122 408.6 0.0 1.9e-122 408.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 GAK63107.1 - 2.8e-42 143.5 0.9 7.9e-42 142.1 0.6 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 GAK63107.1 - 5.5e-07 29.3 0.0 3.1e-06 26.9 0.0 2.4 1 1 0 1 1 1 1 PX domain Aminotran_1_2 PF00155.16 GAK63108.1 - 1.6e-38 132.5 0.0 2.3e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DeoC PF01791.4 GAK63109.1 - 5.5e-45 153.5 4.6 6.5e-45 153.2 3.2 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.16 GAK63109.1 - 0.0069 15.6 0.1 0.074 12.3 0.1 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein OS-D PF03392.8 GAK63109.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D TPR_12 PF13424.1 GAK63110.1 - 0.00017 21.4 0.9 0.51 10.3 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat MOZ_SAS PF01853.13 GAK63111.1 - 1.5e-59 200.3 0.0 7.1e-58 194.9 0.0 2.3 2 0 0 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.3 GAK63111.1 - 4.7e-09 35.8 0.0 9.8e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Methyltransf_23 PF13489.1 GAK63112.1 - 1.2e-13 51.0 0.0 2.8e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK63112.1 - 3.2e-13 50.2 0.0 2.8e-12 47.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK63112.1 - 1.3e-11 44.7 0.0 2.9e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK63112.1 - 4.6e-11 43.0 0.0 1.1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 GAK63112.1 - 3.3e-07 30.0 0.0 5.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.1 GAK63112.1 - 1.6e-06 28.4 0.0 4.2e-06 27.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK63112.1 - 3.1e-05 23.9 0.0 7.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK63112.1 - 3.7e-05 23.3 0.0 0.00017 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK63112.1 - 0.048 13.0 0.0 0.34 10.2 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase small domain DREV PF05219.7 GAK63112.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.12 GAK63112.1 - 0.19 10.7 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CAP PF00188.21 GAK63113.1 - 1.3e-26 93.5 6.6 2.8e-26 92.4 4.6 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-U1 PF06220.7 GAK63113.1 - 0.088 12.3 2.7 0.25 10.9 1.9 1.7 1 0 0 1 1 1 0 U1 zinc finger Collagen PF01391.13 GAK63113.1 - 0.11 12.0 6.7 0.094 12.2 1.9 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Hid1 PF12722.2 GAK63113.1 - 0.37 8.4 3.4 0.46 8.1 2.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 GAK63113.1 - 4.6 5.3 11.1 5.2 5.2 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein E1-E2_ATPase PF00122.15 GAK63114.1 - 2.3e-58 196.9 0.6 4.9e-58 195.8 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAK63114.1 - 4.1e-25 89.4 0.3 6.6e-25 88.7 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAK63114.1 - 2e-16 60.7 0.0 3.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK63114.1 - 4.2e-11 42.1 0.0 1e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAK63114.1 - 0.00014 21.5 0.0 0.00085 18.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2404 PF10296.4 GAK63115.1 - 0.0024 17.9 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DnaJ PF00226.26 GAK63116.1 - 3.4e-24 84.3 0.2 7.4e-24 83.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 GAK63116.1 - 2.4e-22 79.1 0.2 3.8e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) UQ_con PF00179.21 GAK63117.1 - 2.2e-50 169.7 0.0 2.6e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAK63117.1 - 4.9e-07 29.5 0.0 1.4e-06 28.0 0.0 1.6 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 GAK63117.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 RWD domain HSP70 PF00012.15 GAK63118.1 - 1.4e-259 862.1 8.2 1.6e-259 861.9 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAK63118.1 - 1.4e-12 46.8 7.9 6.6e-12 44.6 0.6 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 GAK63118.1 - 2e-05 24.4 2.2 0.13 12.0 0.1 3.6 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 GAK63118.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MAS20 PF02064.10 GAK63119.1 - 8.8e-19 67.5 0.7 7.3e-18 64.6 0.5 2.2 1 1 0 1 1 1 1 MAS20 protein import receptor BNIP2 PF12496.3 GAK63119.1 - 0.012 15.8 0.7 0.012 15.8 0.5 2.1 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Herpes_LMP1 PF05297.6 GAK63119.1 - 3.5 6.4 4.0 5.3 5.8 2.7 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3321 PF11968.3 GAK63120.1 - 3.3e-72 242.6 0.0 4.7e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 GAK63120.1 - 2.2e-05 24.2 0.0 0.00011 22.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain ETF_QO PF05187.8 GAK63121.1 - 2.6e-43 146.4 0.0 4.2e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase FAD_binding_2 PF00890.19 GAK63121.1 - 3.5e-07 29.4 0.5 1.1e-05 24.4 0.6 2.2 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAK63121.1 - 1.7e-06 27.9 0.0 7.1e-06 25.9 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK63121.1 - 2e-06 26.9 1.1 0.00057 18.8 0.7 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK63121.1 - 2.1e-05 23.1 0.5 3.2e-05 22.5 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAK63121.1 - 7.1e-05 22.7 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK63121.1 - 0.00013 21.1 0.3 0.00025 20.2 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAK63121.1 - 0.00021 20.3 0.1 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAK63121.1 - 0.0013 18.5 0.8 0.0029 17.3 0.3 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAK63121.1 - 0.0024 16.9 0.3 0.0041 16.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAK63121.1 - 0.0028 16.7 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAK63121.1 - 0.0031 17.6 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAK63121.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 GAK63121.1 - 0.024 13.2 0.7 0.045 12.3 0.5 1.4 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 GAK63121.1 - 0.026 13.3 0.3 0.04 12.7 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_7 PF12838.2 GAK63121.1 - 0.07 13.5 1.8 0.15 12.4 1.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.1 GAK63121.1 - 0.089 12.6 0.7 0.16 11.8 0.5 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 GAK63121.1 - 4.1 7.4 6.0 0.24 11.3 0.5 1.6 2 0 0 2 2 1 0 4Fe-4S binding domain Barwin PF00967.12 GAK63122.1 - 1.3e-08 34.4 0.1 0.00013 21.6 0.0 2.7 2 0 0 2 2 2 2 Barwin family DPBB_1 PF03330.13 GAK63122.1 - 6.6e-05 22.8 0.9 0.00046 20.1 0.4 2.6 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Mcm10 PF09332.6 GAK63122.1 - 0.028 13.7 2.5 0.044 13.1 1.7 1.2 1 0 0 1 1 1 0 Mcm10 replication factor APC_CDC26 PF10471.4 GAK63122.1 - 4.9 7.9 8.5 7.5 7.3 5.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 FYVE PF01363.16 GAK63123.1 - 1.5e-20 72.8 2.6 2.6e-20 72.0 1.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger TerY-C PF15616.1 GAK63123.1 - 0.033 14.0 0.2 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-DHHC PF01529.15 GAK63123.1 - 0.36 10.2 1.2 0.99 8.7 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Exo_endo_phos PF03372.18 GAK63124.1 - 1.4e-11 44.7 0.1 5.5e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Paf67 PF10255.4 GAK63125.1 - 3.2e-161 536.7 0.2 4.5e-161 536.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 GAK63125.1 - 0.078 12.9 3.1 0.13 12.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Med8 PF10232.4 GAK63125.1 - 0.13 11.7 1.7 0.65 9.4 1.3 2.1 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 ABC1 PF03109.11 GAK63127.1 - 1.5e-24 86.2 0.0 3.1e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family SRF-TF PF00319.13 GAK63128.1 - 3.6e-21 74.1 0.1 5.7e-21 73.5 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Nucleoplasmin PF03066.10 GAK63128.1 - 0.39 10.2 6.3 0.2 11.1 1.4 2.2 2 0 0 2 2 2 0 Nucleoplasmin Sporozoite_P67 PF05642.6 GAK63128.1 - 0.81 7.4 26.5 1.3 6.8 10.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CDC45 PF02724.9 GAK63128.1 - 5 5.0 21.0 0.052 11.5 2.5 2.3 1 1 1 2 2 2 0 CDC45-like protein Pkinase PF00069.20 GAK63130.1 - 1.9e-11 43.6 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAK63130.1 - 1.6e-05 24.8 1.7 0.0033 17.1 0.3 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAK63130.1 - 4.9e-05 22.3 0.0 7.2e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 GAK63130.1 - 0.003 16.5 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK63130.1 - 0.045 12.8 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAK63130.1 - 0.19 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mito_carr PF00153.22 GAK63131.1 - 8.3e-60 198.5 7.4 1e-21 76.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 GAK63131.1 - 0.018 15.1 0.1 0.069 13.2 0.1 2.0 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 GAK63131.1 - 0.019 14.2 2.4 0.084 12.2 0.1 3.1 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.1 GAK63131.1 - 0.053 13.4 0.1 0.26 11.2 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain Mito_fiss_reg PF05308.6 GAK63131.1 - 0.11 11.9 9.5 0.37 10.1 6.6 1.9 1 0 0 1 1 1 0 Mitochondrial fission regulator Tubulin PF00091.20 GAK63132.1 - 5.3e-69 232.3 0.0 7e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAK63132.1 - 1.4e-45 154.3 0.0 2.2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAK63132.1 - 0.00045 19.7 0.0 0.0011 18.4 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain RNB PF00773.14 GAK63133.1 - 3.1e-102 342.2 0.0 7.1e-102 341.0 0.0 1.7 1 0 0 1 1 1 1 RNB domain DUF3881 PF12997.2 GAK63133.1 - 0.0098 14.9 0.2 0.018 14.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3881) DEAD PF00270.24 GAK63134.1 - 7.5e-39 132.9 0.0 1.5e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 GAK63134.1 - 2.2e-21 75.4 1.0 2.2e-21 75.4 0.7 3.1 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 GAK63134.1 - 1.5e-20 72.8 0.0 5e-20 71.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK63134.1 - 0.0012 18.6 0.0 0.0063 16.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Vps53_N PF04100.7 GAK63136.1 - 2.5e-90 303.0 0.1 4.1e-90 302.3 0.1 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 GAK63136.1 - 0.0081 15.1 6.1 0.014 14.3 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 GAK63136.1 - 0.03 12.5 4.7 0.023 12.8 1.7 1.9 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 FlxA PF14282.1 GAK63136.1 - 0.95 9.4 7.0 3.4 7.6 4.9 2.1 1 0 0 1 1 1 0 FlxA-like protein Reo_sigmaC PF04582.7 GAK63137.1 - 0.55 9.3 34.8 0.13 11.4 1.0 4.4 1 1 4 5 5 5 0 Reovirus sigma C capsid protein PIG-P PF08510.7 GAK63138.1 - 8.5e-31 106.2 0.8 1.2e-30 105.7 0.6 1.2 1 0 0 1 1 1 1 PIG-P CIA30 PF08547.7 GAK63138.1 - 8.8e-15 54.8 0.0 2.9e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) DUF4131 PF13567.1 GAK63138.1 - 0.083 12.3 3.1 0.14 11.5 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DPM2 PF07297.7 GAK63138.1 - 0.76 10.1 3.8 1.4 9.2 2.6 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HIT PF01230.18 GAK63139.1 - 3.8e-20 72.2 1.3 6e-20 71.6 0.4 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 GAK63139.1 - 9.3e-15 54.8 0.3 2.3e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 GAK63139.1 - 1.9e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rax2 PF12768.2 GAK63141.1 - 4.9e-76 255.6 9.5 4.1e-63 213.2 0.0 4.5 5 1 1 6 6 6 3 Cortical protein marker for cell polarity SH3_1 PF00018.23 GAK63141.1 - 5.5e-13 48.0 0.0 1.3e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAK63141.1 - 3.1e-11 42.6 0.1 1.1e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 GAK63141.1 - 5.6e-07 28.9 0.0 1.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1918 PF08940.6 GAK63141.1 - 0.011 15.0 0.1 0.078 12.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) CcoS PF03597.10 GAK63141.1 - 7.7 6.0 7.7 27 4.3 5.4 2.0 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Metallophos PF00149.23 GAK63142.1 - 7.8e-39 133.1 1.0 1.1e-38 132.6 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAK63142.1 - 0.0079 16.0 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mito_carr PF00153.22 GAK63143.1 - 2.3e-09 36.8 0.1 0.00025 20.6 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein DUF3311 PF11755.3 GAK63143.1 - 0.024 14.1 0.0 0.081 12.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Neisseria_TspB PF05616.8 GAK63145.1 - 5.2 5.3 7.5 7.3 4.8 5.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein CMV_1a PF12467.3 GAK63146.1 - 0.38 11.1 4.0 0.54 10.6 2.7 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Ribosom_S12_S23 PF00164.20 GAK63147.1 - 6.5e-38 128.9 0.7 9e-38 128.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L27e PF01777.13 GAK63148.1 - 4.9e-38 129.1 2.1 7.5e-38 128.5 1.5 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 GAK63148.1 - 0.55 10.0 2.3 0.45 10.3 0.2 2.0 2 0 0 2 2 2 0 KOW motif SecY PF00344.15 GAK63149.1 - 2.7e-97 325.7 7.1 3.5e-97 325.4 4.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 GAK63149.1 - 3.9e-18 64.6 0.2 1.3e-17 63.0 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.6 GAK63149.1 - 0.084 12.5 2.8 1.3 8.7 0.0 3.4 3 1 0 3 3 3 0 Tight junction protein, Claudin-like RNA_pol_N PF01194.12 GAK63150.1 - 2.6e-28 97.8 0.4 3.7e-28 97.3 0.3 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit BRE1 PF08647.6 GAK63151.1 - 6.1e-24 83.8 7.9 6.1e-24 83.8 5.5 7.8 5 1 3 8 8 8 2 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 GAK63151.1 - 1.2e-05 25.2 12.5 1.9e-05 24.5 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK63151.1 - 1.6e-05 24.5 12.8 2.9e-05 23.6 8.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAK63151.1 - 2e-05 24.1 13.0 3.3e-05 23.4 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK63151.1 - 0.00014 21.4 9.7 0.00024 20.6 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin PF00261.15 GAK63151.1 - 0.00055 19.0 16.3 0.00055 19.0 11.3 5.6 3 1 2 5 5 4 2 Tropomyosin zf-RING_6 PF14835.1 GAK63151.1 - 0.00063 19.4 2.5 0.0012 18.5 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 GAK63151.1 - 0.0014 18.3 11.0 0.0025 17.6 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain Lebercilin PF15619.1 GAK63151.1 - 0.0015 18.0 18.1 0.0015 18.0 12.6 6.8 3 2 5 8 8 6 1 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.16 GAK63151.1 - 0.0075 15.7 83.0 0.12 11.8 5.5 6.2 2 1 4 6 6 6 4 Intermediate filament protein zf-rbx1 PF12678.2 GAK63151.1 - 0.16 12.0 5.9 0.31 11.1 4.1 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1272 PF06906.6 GAK63151.1 - 0.71 9.7 4.7 1.7 8.5 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 GAK63151.1 - 1.3 8.9 8.3 2.3 8.1 5.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Tropomyosin_1 PF12718.2 GAK63151.1 - 2.1 8.1 88.8 0.082 12.7 13.9 5.8 2 1 4 6 6 6 0 Tropomyosin like Myosin_tail_1 PF01576.14 GAK63151.1 - 3.7 5.1 100.1 11 3.5 59.1 4.0 2 2 0 2 2 2 0 Myosin tail Pam17 PF08566.5 GAK63152.1 - 0.0017 18.0 0.9 0.0061 16.2 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial import protein Pam17 PWWP PF00855.12 GAK63153.1 - 1.3e-15 57.3 0.0 1.3e-15 57.3 0.0 3.1 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 GAK63153.1 - 3.8e-05 23.1 0.0 8.6e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Daxx PF03344.10 GAK63153.1 - 0.35 9.3 18.3 0.41 9.0 12.7 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 GAK63153.1 - 0.55 9.2 28.1 0.093 11.7 16.7 1.7 2 0 0 2 2 2 0 BUD22 NOA36 PF06524.7 GAK63153.1 - 0.7 9.0 6.5 1.1 8.3 4.5 1.4 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.2 GAK63153.1 - 3.1 5.3 8.0 3.7 5.1 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 GAK63153.1 - 3.5 5.5 14.7 5.4 4.9 10.2 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 GAK63154.1 - 2.3e-51 175.8 21.7 9.8e-32 111.2 12.9 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF1958 PF09211.5 GAK63154.1 - 0.085 12.9 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) HSF_DNA-bind PF00447.12 GAK63155.1 - 3.6e-36 123.4 0.2 5.5e-36 122.8 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Brix PF04427.13 GAK63158.1 - 1.8e-43 148.4 0.1 2.4e-43 148.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain GHMP_kinases_N PF00288.21 GAK63159.1 - 3.4e-09 36.6 1.8 9.4e-09 35.2 1.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAK63159.1 - 0.085 13.0 0.0 1.1 9.4 0.0 2.8 3 1 0 3 3 3 0 GHMP kinases C terminal Sybindin PF04099.7 GAK63160.1 - 2.1e-06 27.4 0.0 9.5e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 Sybindin-like family Med3 PF11593.3 GAK63160.1 - 8.2 5.5 12.2 10 5.2 8.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EMP70 PF02990.11 GAK63161.1 - 1.3e-180 601.3 0.1 1.7e-180 600.9 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Serinc PF03348.10 GAK63162.1 - 1.5e-148 495.1 3.8 1.8e-148 494.8 2.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FA_desaturase PF00487.19 GAK63162.1 - 0.48 9.8 12.8 3 7.2 6.4 2.8 2 1 0 2 2 2 0 Fatty acid desaturase YtpI PF14007.1 GAK63162.1 - 1.4 8.9 12.9 0.11 12.4 2.5 3.1 3 0 0 3 3 3 0 YtpI-like protein DUF2431 PF10354.4 GAK63163.1 - 7.1e-27 94.3 0.0 5.1e-24 85.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) TPR_11 PF13414.1 GAK63165.1 - 1.3e-26 92.0 12.6 1.5e-13 50.1 0.5 5.1 4 1 1 5 5 4 4 TPR repeat TPR_1 PF00515.23 GAK63165.1 - 2.7e-22 77.3 2.7 0.00014 21.2 0.0 7.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAK63165.1 - 7e-21 74.3 13.1 1.2e-08 35.4 1.6 5.6 3 2 3 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.26 GAK63165.1 - 2.6e-19 68.7 2.7 5.4e-19 67.7 0.1 2.9 3 0 0 3 3 3 1 DnaJ domain TPR_2 PF07719.12 GAK63165.1 - 3.9e-18 63.8 10.1 0.0028 17.4 0.0 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAK63165.1 - 5.9e-16 58.5 24.4 1.5e-06 28.4 2.5 6.1 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 GAK63165.1 - 2.6e-15 56.0 14.8 1.6e-07 31.0 0.5 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAK63165.1 - 2.6e-12 45.5 3.0 0.031 14.0 0.2 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAK63165.1 - 3.7e-12 45.7 20.4 0.021 15.4 0.0 7.7 5 2 3 8 8 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAK63165.1 - 4.7e-11 41.9 7.4 0.033 14.3 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 GAK63165.1 - 6.4e-10 39.0 14.7 0.0003 20.8 0.3 4.7 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAK63165.1 - 1.3e-06 28.4 20.3 0.032 14.7 0.1 7.6 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAK63165.1 - 9.9e-06 25.4 18.3 0.002 18.0 1.2 5.2 5 1 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAK63165.1 - 4e-05 23.0 6.7 8.2 6.4 0.0 6.4 6 1 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAK63165.1 - 8.8e-05 22.3 2.1 8.2 6.3 0.0 5.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 GAK63165.1 - 0.0002 21.4 16.1 0.013 15.5 1.0 5.2 3 1 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 GAK63165.1 - 0.0023 17.7 2.0 2.7 7.8 0.0 3.6 2 1 0 2 2 2 2 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 GAK63165.1 - 0.013 14.7 0.3 0.013 14.7 0.2 2.4 3 0 0 3 3 3 0 SHNi-TPR BTAD PF03704.12 GAK63165.1 - 0.077 13.2 0.4 0.077 13.2 0.3 3.9 2 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 GAK63165.1 - 0.085 13.3 8.2 21 5.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Spectrin PF00435.16 GAK63165.1 - 0.21 11.9 10.0 0.61 10.4 1.1 4.2 3 2 0 3 3 3 0 Spectrin repeat SgrR_N PF12793.2 GAK63165.1 - 1.7 8.6 5.7 2.7 8.0 0.1 3.6 4 1 1 5 5 4 0 Sugar transport-related sRNA regulator N-term DUF4398 PF14346.1 GAK63165.1 - 2.8 8.0 28.1 0.74 9.8 0.2 5.0 3 2 1 4 4 4 0 Domain of unknown function (DUF4398) PIN_4 PF13638.1 GAK63166.1 - 6.6e-18 65.0 0.2 6.6e-18 65.0 0.1 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 GAK63166.1 - 9.2e-18 64.4 0.0 1.9e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Pterin_bind PF00809.17 GAK63167.1 - 6.2e-61 205.4 0.0 2.1e-60 203.6 0.0 1.9 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.13 GAK63167.1 - 4.2e-51 171.8 4.1 8.1e-27 93.6 0.8 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.15 GAK63167.1 - 1.3e-39 134.8 0.0 3e-39 133.6 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 2-Hacid_dh_C PF02826.14 GAK63170.1 - 6.7e-47 158.9 0.0 9.8e-47 158.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAK63170.1 - 4.1e-21 74.8 0.0 5.9e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Thioredoxin_6 PF13848.1 GAK63170.1 - 0.054 13.2 0.0 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain SNF2_N PF00176.18 GAK63171.1 - 1.6e-58 197.8 0.0 2.2e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK63171.1 - 6.5e-14 51.5 0.1 9.9e-13 47.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK63171.1 - 8e-08 32.3 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_8 PF02954.14 GAK63171.1 - 0.033 13.7 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HHH_3 PF12836.2 GAK63171.1 - 0.096 12.6 0.0 0.38 10.7 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif BC10 PF06726.7 GAK63172.1 - 7.2e-19 67.5 7.9 1.6e-18 66.4 5.5 1.6 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Bromodomain PF00439.20 GAK63173.1 - 1e-25 89.4 0.0 2.2e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 GAK63173.1 - 1.1e-09 38.3 0.2 1.9e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAK63173.1 - 1.9e-08 34.2 0.1 4.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1777 PF08648.7 GAK63173.1 - 0.92 9.2 15.9 1.3 8.7 10.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) ANTH PF07651.11 GAK63174.1 - 8.5e-51 172.3 0.0 1.2e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 GAK63174.1 - 2.8e-05 23.9 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 GAK63174.1 - 0.00045 20.2 29.3 0.00045 20.2 20.3 7.2 2 1 3 5 5 5 2 Domain of unknown function (DUF1720) AMP-binding PF00501.23 GAK63175.1 - 1.4e-241 801.1 0.0 2.3e-85 286.5 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAK63175.1 - 9.3e-109 362.9 0.0 1.2e-27 96.6 0.0 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 GAK63175.1 - 5.3e-40 135.5 0.4 5.1e-09 36.2 0.0 5.1 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAK63175.1 - 1.2e-16 61.3 0.8 3.9e-07 30.9 0.0 4.8 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.1 GAK63176.1 - 6.9e-85 284.9 0.0 4.4e-84 282.3 0.0 2.0 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 GAK63176.1 - 6.4e-09 36.1 0.1 5.6e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK63176.1 - 1.6e-08 34.4 2.3 3.1e-06 27.0 0.0 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding zf-CCCH PF00642.19 GAK63177.1 - 9.5e-09 34.7 2.5 9.5e-09 34.7 1.7 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 GAK63177.1 - 2.2e-08 33.9 7.6 4e-08 33.1 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK63177.1 - 2.9e-07 30.0 4.8 5.2e-07 29.2 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK63177.1 - 9.9e-07 28.3 7.8 1.7e-06 27.6 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAK63177.1 - 6.9e-06 25.7 6.2 1.2e-05 25.0 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAK63177.1 - 8.4e-05 22.1 7.2 0.00016 21.2 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAK63177.1 - 0.00013 21.7 5.8 0.00029 20.6 4.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAK63177.1 - 0.00017 21.2 3.9 0.00038 20.1 2.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 GAK63177.1 - 0.012 15.1 2.0 0.024 14.1 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3245 PF11595.3 GAK63177.1 - 0.025 14.8 0.8 0.056 13.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) TFIIF_alpha PF05793.7 GAK63177.1 - 0.49 8.6 7.0 0.7 8.1 4.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-rbx1 PF12678.2 GAK63177.1 - 0.8 9.8 3.7 2.1 8.4 2.6 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger GATase_5 PF13507.1 GAK63178.1 - 9.3e-90 300.0 0.0 1.5e-89 299.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 GAK63178.1 - 3.5e-44 150.4 3.5 3.6e-21 75.7 0.0 2.7 2 1 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 GAK63178.1 - 4.4e-21 74.9 1.9 1.9e-20 72.8 0.0 3.1 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Phosducin PF02114.11 GAK63179.1 - 8e-22 77.2 0.1 7.7e-21 73.9 0.1 2.2 1 1 0 1 1 1 1 Phosducin YliH PF10799.3 GAK63179.1 - 0.054 13.1 2.7 2.8 7.6 0.4 2.9 3 0 0 3 3 3 0 Biofilm formation protein (YliH/bssR) tRNA-synt_1 PF00133.17 GAK63180.1 - 1.1e-222 740.3 0.0 1.4e-222 739.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAK63180.1 - 5.6e-23 81.3 0.0 1.1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAK63180.1 - 6.5e-17 61.2 1.8 4.4e-06 25.6 0.3 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAK63180.1 - 0.0019 17.4 0.0 0.0054 15.8 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-C2H2_jaz PF12171.3 GAK63181.1 - 1.1e-05 25.3 0.1 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 GAK63181.1 - 4.3e-05 23.3 8.5 4.3e-05 23.3 5.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-met PF12874.2 GAK63181.1 - 0.00018 21.5 0.2 0.00031 20.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF2413 PF10310.4 GAK63181.1 - 0.0028 16.5 2.5 0.0043 15.9 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF3340 PF11818.3 GAK63181.1 - 0.25 11.3 7.5 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Nup96 PF12110.3 GAK63182.1 - 3.8e-94 315.0 0.0 5.2e-94 314.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 GAK63182.1 - 2.3e-42 144.1 0.0 6.2e-42 142.7 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 GAK63182.1 - 1.2e-28 99.5 427.9 1.2e-07 31.9 41.2 11.7 3 2 8 11 11 11 8 Nucleoporin FG repeat region GNAT_acetyltr_2 PF13718.1 GAK63182.1 - 0.2 10.9 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DZR PF12773.2 GAK63183.1 - 0.062 13.1 40.2 1.8 8.4 3.6 5.1 2 2 2 4 4 4 0 Double zinc ribbon UCH PF00443.24 GAK63184.1 - 0.023 13.8 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Mer2 PF09074.5 GAK63184.1 - 0.096 12.6 1.0 1.7 8.5 0.6 2.6 1 1 0 1 1 1 0 Mer2 Rep_fac-A_C PF08646.5 GAK63185.1 - 2.5e-57 192.6 3.6 3.2e-55 185.8 0.2 2.2 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 GAK63185.1 - 5.1e-27 93.6 0.7 1.2e-26 92.3 0.5 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 GAK63185.1 - 5.4e-13 48.5 0.1 4.5e-11 42.4 0.0 3.1 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 GAK63185.1 - 0.0098 15.9 0.2 0.027 14.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF223 EB PF01683.13 GAK63187.1 - 0.0023 17.9 77.0 0.063 13.3 8.2 6.7 1 1 6 7 7 7 6 EB module Dickkopf_N PF04706.7 GAK63187.1 - 0.022 14.9 14.6 0.022 14.9 10.1 5.2 4 1 1 5 5 5 0 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.3 GAK63187.1 - 6.2 6.8 67.8 2.2 8.2 1.1 5.8 3 2 0 4 4 4 0 UPF0506 Mannosyl_trans3 PF11051.3 GAK63188.1 - 1.5e-52 178.6 0.0 2.2e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.3 GAK63189.1 - 4.9e-53 180.2 0.0 6.8e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Cyclin_N PF00134.18 GAK63190.1 - 1.4e-08 34.3 0.0 2.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 GAK63190.1 - 0.0094 15.7 0.0 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 Transcription factor TFIIB repeat RabGAP-TBC PF00566.13 GAK63192.1 - 3.5e-49 167.1 0.0 4.7e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.23 GAK63192.1 - 0.0085 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Glyco_transf_90 PF05686.7 GAK63193.1 - 3.4e-17 62.2 0.0 2.6e-14 52.7 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 90 Abhydrolase_3 PF07859.8 GAK63194.1 - 1.7e-30 106.1 0.1 2.3e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK63194.1 - 4.7e-08 33.2 0.8 6.7e-08 32.6 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK63194.1 - 3.1e-06 26.9 0.1 5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAK63194.1 - 0.00023 20.5 0.2 0.021 14.1 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 GAK63194.1 - 0.00095 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 GAK63194.1 - 0.002 17.4 0.1 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 GAK63194.1 - 0.0085 16.3 0.0 0.018 15.2 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain DUF2305 PF10230.4 GAK63194.1 - 0.033 13.6 0.0 0.07 12.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) BAAT_C PF08840.6 GAK63194.1 - 0.096 12.3 0.0 0.58 9.8 0.0 2.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ku PF02735.11 GAK63195.1 - 2.7e-30 105.3 0.0 6.9e-30 103.9 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 GAK63195.1 - 4.7e-20 71.9 0.0 2.4e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 GAK63195.1 - 7.7e-08 32.7 0.1 2e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 GAK63195.1 - 1.3e-07 30.9 0.0 2.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 SAP domain VHS PF00790.14 GAK63195.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 VHS domain adh_short_C2 PF13561.1 GAK63196.1 - 7.4e-31 107.7 0.1 8.9e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK63196.1 - 1.4e-19 70.5 0.0 1.9e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK63196.1 - 8.9e-08 31.9 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAK63196.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein His_biosynth PF00977.16 GAK63196.1 - 0.016 14.5 0.1 0.046 12.9 0.0 1.7 2 1 0 2 2 2 0 Histidine biosynthesis protein Cbl_N3 PF02762.9 GAK63196.1 - 0.14 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Ribosomal_L39 PF00832.15 GAK63197.1 - 2.9e-16 58.6 10.1 1.6e-13 49.8 2.2 2.4 2 0 0 2 2 2 2 Ribosomal L39 protein Acetyltransf_1 PF00583.19 GAK63198.1 - 1.1e-05 25.3 0.2 0.0095 15.9 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK63198.1 - 8e-05 22.7 0.0 0.00061 19.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAK63198.1 - 0.014 15.2 0.2 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK63198.1 - 0.019 14.7 0.1 3.8 7.3 0.0 3.0 3 0 0 3 3 3 0 FR47-like protein Acetyltransf_10 PF13673.1 GAK63198.1 - 0.042 13.9 0.1 1.6 8.8 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.21 GAK63199.1 - 1e-11 44.4 16.5 0.00039 20.6 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK63199.1 - 5.8e-09 35.7 10.5 0.0013 18.8 0.0 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAK63199.1 - 8.5e-09 35.1 15.1 0.0008 19.5 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAK63199.1 - 0.00031 20.5 9.6 0.0078 16.0 0.2 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger Suf PF05843.9 GAK63199.1 - 1.8 8.2 7.1 4.6 6.8 4.9 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NAP PF00956.13 GAK63200.1 - 6.2e-87 290.7 4.7 6.2e-87 290.7 3.3 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) S-antigen PF05756.6 GAK63200.1 - 4.1 7.4 8.7 0.66 9.9 2.3 2.4 2 0 0 2 2 2 0 S-antigen protein Peptidase_C54 PF03416.14 GAK63201.1 - 7.5e-86 287.7 0.0 4.6e-85 285.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C54 IMS PF00817.15 GAK63202.1 - 1.3e-45 154.8 0.1 2.3e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAK63202.1 - 4e-14 52.6 1.6 1e-13 51.3 1.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAK63202.1 - 3.3e-06 26.8 0.0 8.8e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif F1F0-ATPsyn_F PF10791.4 GAK63203.1 - 4.9e-33 113.2 0.0 5.9e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Ribosomal_S5 PF00333.15 GAK63204.1 - 7.7e-28 96.0 2.9 1.8e-27 94.8 0.8 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 GAK63204.1 - 5.6e-22 76.8 0.0 9.4e-22 76.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain MUG113 PF13455.1 GAK63205.1 - 2.7e-18 66.2 0.1 5.4e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 GAK63205.1 - 1.2e-11 44.9 0.0 3.3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain Ribosomal_S2 PF00318.15 GAK63206.1 - 1e-43 149.0 0.0 7.3e-21 74.3 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Zn_clus PF00172.13 GAK63207.1 - 2.9e-08 33.4 11.1 5.6e-08 32.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK63207.1 - 0.00024 20.0 0.0 0.0021 16.9 0.0 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MPC PF03650.8 GAK63208.1 - 4.8e-39 132.9 0.2 5.7e-39 132.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF3684 PF12449.3 GAK63209.1 - 0 1293.6 0.0 0 1293.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 GAK63209.1 - 0.064 12.9 0.0 0.4 10.3 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Na_Ca_ex PF01699.19 GAK63210.1 - 6.4e-37 126.2 40.4 3.4e-20 72.0 10.6 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Glyco_transf_22 PF03901.12 GAK63210.1 - 0.018 14.0 0.4 0.018 14.0 0.3 3.5 2 1 1 3 3 3 0 Alg9-like mannosyltransferase family SH PF01445.12 GAK63210.1 - 0.08 12.6 4.0 0.087 12.4 0.1 2.9 2 0 0 2 2 2 0 Viral small hydrophobic protein RBM1CTR PF08081.6 GAK63210.1 - 0.12 12.0 0.5 0.3 10.8 0.4 1.6 1 0 0 1 1 1 0 RBM1CTR (NUC064) family DUF4611 PF15387.1 GAK63210.1 - 0.59 10.3 3.9 0.74 9.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AMP-binding PF00501.23 GAK63211.1 - 2.3e-48 164.6 0.0 3.2e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK63211.1 - 0.00033 21.5 0.0 0.00087 20.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PEPCK_ATP PF01293.15 GAK63212.1 - 5.8e-221 733.9 0.0 7e-221 733.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 GAK63212.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAK63212.1 - 0.23 11.4 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain UPF0197 PF05251.7 GAK63213.1 - 1.1 9.6 5.3 0.59 10.4 1.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0197) CDC73 PF05179.9 GAK63214.1 - 2.5e-48 164.7 2.4 4.5e-48 163.9 1.6 1.4 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Nol1_Nop2_Fmu PF01189.12 GAK63215.1 - 8.8e-30 104.0 0.0 5.3e-18 65.3 0.0 3.7 2 1 1 3 3 3 3 NOL1/NOP2/sun family Pribosyltran PF00156.22 GAK63215.1 - 2.8e-15 56.1 0.3 5.1e-15 55.2 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FtsJ PF01728.14 GAK63215.1 - 0.12 12.2 0.0 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase tRNA-synt_1c PF00749.16 GAK63216.1 - 1.6e-103 345.6 0.0 2.3e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 GAK63216.1 - 2.1e-39 134.6 0.0 3.4e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 GAK63216.1 - 8.1e-35 120.0 0.0 3.8e-34 117.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 GAK63216.1 - 1.4e-16 60.9 3.7 1.4e-16 60.9 2.6 3.0 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 G-alpha PF00503.15 GAK63217.1 - 7.7e-130 433.0 1.0 9.3e-130 432.8 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAK63217.1 - 1.9e-17 63.0 0.8 4.9e-12 45.4 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 GAK63217.1 - 5.4e-05 22.6 0.1 0.00021 20.7 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 GAK63217.1 - 0.00014 22.3 0.0 0.33 11.4 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 GAK63217.1 - 0.00031 19.9 6.2 0.0015 17.7 0.4 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAK63217.1 - 0.0068 16.3 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 GAK63217.1 - 0.0068 15.9 0.2 0.045 13.2 0.1 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 GAK63217.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 GAK63217.1 - 0.033 13.6 0.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pyridoxal_deC PF00282.14 GAK63219.1 - 9.5e-22 76.9 0.0 1.7e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAK63219.1 - 6.3e-07 28.4 0.0 1.4e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAK63219.1 - 0.0088 15.1 0.1 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 GAK63219.1 - 0.1 10.8 0.0 0.18 10.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAK63219.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II tRNA-synt_2 PF00152.15 GAK63220.1 - 4.7e-86 288.5 0.0 6.4e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Aldo_ket_red PF00248.16 GAK63220.1 - 2.2e-40 138.2 0.0 5.2e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA_anti-codon PF01336.20 GAK63220.1 - 2.6e-11 43.1 0.0 5.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAK63220.1 - 7.1e-08 31.9 0.0 0.00012 21.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 GAK63220.1 - 0.037 13.6 0.1 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_L1 PF00687.16 GAK63220.1 - 0.088 12.1 0.0 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L1p/L10e family Sugar_tr PF00083.19 GAK63221.1 - 7e-37 127.0 23.2 2.7e-35 121.8 16.1 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK63221.1 - 3.9e-30 104.7 30.9 3.9e-30 104.7 21.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAK63221.1 - 6.8e-05 21.4 15.1 0.00061 18.2 0.3 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 GAK63221.1 - 0.00022 19.8 21.6 0.015 13.8 6.7 2.1 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Hamartin PF04388.7 GAK63223.1 - 1.5e-38 132.9 10.4 1.5e-38 132.9 7.2 3.1 2 1 0 2 2 2 1 Hamartin protein zf-4CXXC_R1 PF10497.4 GAK63224.1 - 6.2e-06 26.3 12.9 0.0009 19.3 8.9 2.5 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 POT1 PF02765.12 GAK63225.1 - 2.3e-18 66.5 0.0 6.6e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 zf-ribbon_3 PF13248.1 GAK63225.1 - 0.0072 15.5 0.3 0.016 14.3 0.2 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 GAK63225.1 - 0.012 15.4 1.0 0.025 14.3 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAK63225.1 - 0.013 14.9 1.1 0.024 14.1 0.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 GAK63225.1 - 0.071 12.9 0.2 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like UPF0547 PF10571.4 GAK63225.1 - 1.4 8.6 4.5 0.65 9.7 1.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 EF_TS PF00889.14 GAK63226.1 - 2e-15 56.7 0.0 1.8e-13 50.3 0.0 2.9 2 1 1 3 3 3 2 Elongation factor TS LRR_8 PF13855.1 GAK63227.1 - 5.5e-13 48.4 13.3 2.5e-10 39.9 4.5 3.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 GAK63227.1 - 1.4e-10 40.5 16.6 2.7e-06 26.8 1.9 5.0 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAK63227.1 - 2.7e-05 23.5 15.1 0.08 13.0 0.3 5.6 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 GAK63227.1 - 9.8e-05 22.0 4.6 4.4 7.6 0.1 5.1 6 0 0 6 6 6 3 Leucine Rich repeat ABC_membrane PF00664.18 GAK63228.1 - 8.7e-79 264.7 24.5 5.1e-42 144.1 5.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAK63228.1 - 3e-61 205.7 0.0 9.9e-32 110.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAK63228.1 - 4.3e-13 49.0 0.1 0.0002 20.6 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAK63228.1 - 2.1e-09 37.7 0.0 0.15 11.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 GAK63228.1 - 6.8e-09 35.3 0.4 0.015 14.7 0.0 4.5 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 GAK63228.1 - 3.6e-07 31.0 0.0 0.0051 17.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 GAK63228.1 - 1.2e-06 27.4 0.3 0.00079 18.1 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 GAK63228.1 - 2e-06 27.9 2.1 1.6 8.9 0.0 4.4 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 GAK63228.1 - 1.4e-05 24.4 0.5 0.052 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 GAK63228.1 - 0.00013 21.1 0.0 0.39 9.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 GAK63228.1 - 0.0016 18.3 3.8 0.24 11.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 GAK63228.1 - 0.0019 18.0 10.2 0.15 11.9 0.3 4.5 3 3 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 GAK63228.1 - 0.0023 18.2 0.0 0.48 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAK63228.1 - 0.0033 16.9 0.6 2 7.7 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain APS_kinase PF01583.15 GAK63228.1 - 0.0035 16.9 0.1 0.094 12.3 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase SRP54 PF00448.17 GAK63228.1 - 0.0037 16.7 0.0 0.56 9.6 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 GAK63228.1 - 0.005 16.5 0.0 4.4 7.0 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAK63228.1 - 0.006 15.7 0.0 3.8 6.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 GAK63228.1 - 0.0093 15.1 0.1 0.052 12.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 GAK63228.1 - 0.05 13.4 2.6 1.5 8.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 G-alpha PF00503.15 GAK63228.1 - 0.06 12.0 1.7 5.8 5.4 0.0 3.0 3 0 0 3 3 3 0 G-protein alpha subunit AAA_5 PF07728.9 GAK63228.1 - 0.082 12.6 0.3 1.7 8.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PRK PF00485.13 GAK63228.1 - 0.2 11.1 0.9 12 5.3 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family PALP PF00291.20 GAK63229.1 - 5.3e-78 262.3 0.4 7e-78 261.9 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 GAK63229.1 - 3.3e-44 148.4 0.0 2.8e-25 87.7 0.0 3.6 4 0 0 4 4 4 3 C-terminal regulatory domain of Threonine dehydratase MMR_HSR1 PF01926.18 GAK63230.1 - 1.8e-18 66.5 0.0 1.2e-13 51.0 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK63230.1 - 1.7e-09 37.1 0.0 9.3e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAK63230.1 - 8.1e-06 25.3 0.0 0.00037 19.9 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAK63230.1 - 2.6e-05 24.1 0.2 0.03 14.1 0.1 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 GAK63230.1 - 0.0066 15.6 0.1 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAK63230.1 - 0.016 15.6 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein tRNA-synt_1b PF00579.20 GAK63231.1 - 1.2e-67 228.1 0.0 1.7e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 GAK63231.1 - 0.0029 17.0 0.1 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain MgtE_N PF03448.12 GAK63231.1 - 0.039 14.2 0.5 0.065 13.5 0.3 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain WD40 PF00400.27 GAK63232.1 - 4.2e-89 289.5 16.4 9.4e-10 38.0 0.1 11.8 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 GAK63232.1 - 9.1e-32 109.6 0.2 1.6e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 GAK63232.1 - 6.8e-07 28.3 5.0 0.52 8.9 0.0 6.8 3 3 3 7 7 7 3 Nup133 N terminal like Nup160 PF11715.3 GAK63232.1 - 0.00041 18.6 12.5 1.1 7.3 1.4 6.4 5 2 0 5 5 5 2 Nucleoporin Nup120/160 Peptidase_M14 PF00246.19 GAK63233.1 - 1.2e-60 205.5 0.0 3.1e-60 204.1 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase Trypan_PARP PF05887.6 GAK63233.1 - 0.0037 17.0 5.3 0.0076 16.0 3.7 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) tRNA-synt_1 PF00133.17 GAK63234.1 - 3.9e-36 124.2 0.0 4.9e-28 97.5 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 GAK63234.1 - 2.6e-18 65.8 0.0 8.9e-11 41.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAK63234.1 - 5.8e-13 48.8 0.0 1.3e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 GAK63234.1 - 1.4e-06 27.6 0.0 3.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Med12 PF09497.5 GAK63235.1 - 3.2e-30 103.8 0.0 3.3e-29 100.6 0.0 2.5 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 GAK63235.1 - 3.7e-05 22.4 0.0 0.0001 20.9 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain ARPC4 PF05856.7 GAK63236.1 - 1.6e-68 229.3 6.3 1.8e-68 229.2 4.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Mito_carr PF00153.22 GAK63237.1 - 2.1e-46 155.5 9.3 9.9e-19 66.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-sulfurylase PF01747.12 GAK63239.1 - 1.1e-87 292.9 0.2 1.5e-87 292.4 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 GAK63239.1 - 7.9e-55 184.8 0.0 1.2e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 GAK63239.1 - 3.9e-53 179.1 0.0 6.1e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 GAK63239.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NDUF_B12 PF08122.7 GAK63240.1 - 5.3e-22 77.3 0.4 6.2e-22 77.0 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Topoisom_I_N PF02919.10 GAK63241.1 - 1.5e-83 279.2 0.2 1.5e-83 279.2 0.2 3.9 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 GAK63241.1 - 1.4e-67 227.2 5.4 1.4e-67 227.2 3.7 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 GAK63241.1 - 1.8e-15 56.3 0.4 3.1e-11 42.7 0.1 2.9 2 0 0 2 2 2 2 C-terminal topoisomerase domain RPEL PF02755.10 GAK63242.1 - 6.2e-30 101.6 40.8 1.8e-09 36.6 1.1 5.2 6 0 0 6 6 6 4 RPEL repeat Antimicrobial18 PF08130.6 GAK63242.1 - 0.0019 18.0 0.8 2.2 8.2 0.0 3.2 3 0 0 3 3 3 1 Type A lantibiotic family DnaI_N PF07319.6 GAK63242.1 - 0.0074 16.5 0.2 4.5 7.5 0.0 2.6 1 1 2 3 3 3 2 Primosomal protein DnaI N-terminus DUF1992 PF09350.5 GAK63242.1 - 0.019 14.7 4.6 2.4 8.0 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1992) UvsW PF11637.3 GAK63242.1 - 0.072 12.7 0.4 5.8 6.6 0.0 3.0 3 0 0 3 3 3 0 ATP-dependant DNA helicase UvsW DnaB_C PF03796.10 GAK63242.1 - 0.31 9.8 2.5 2 7.2 1.3 2.4 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Alb1 PF09135.6 GAK63242.1 - 0.36 11.4 5.3 1.8 9.1 3.7 2.1 1 1 0 1 1 1 0 Alb1 Phe_tRNA-synt_N PF02912.13 GAK63242.1 - 1.3 8.8 7.8 12 5.7 0.2 3.3 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain TPR_11 PF13414.1 GAK63243.1 - 1.1e-26 92.2 6.0 1.8e-13 49.9 0.0 4.1 3 1 1 4 4 3 3 TPR repeat TPR_1 PF00515.23 GAK63243.1 - 4.5e-21 73.5 2.7 9.8e-05 21.7 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAK63243.1 - 1.8e-14 52.4 11.4 0.00039 20.1 0.1 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAK63243.1 - 3.9e-14 52.3 6.1 7.7e-07 28.9 0.0 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAK63243.1 - 2.3e-13 49.1 4.0 0.0047 17.0 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAK63243.1 - 4e-11 42.5 9.1 0.0074 16.8 0.0 6.8 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAK63243.1 - 1.4e-10 41.4 11.7 4.8e-06 27.0 0.0 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAK63243.1 - 5.9e-09 35.0 5.8 0.044 13.5 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAK63243.1 - 1.6e-07 31.5 7.5 0.01 16.1 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAK63243.1 - 7e-07 28.5 4.1 0.8 9.6 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 GAK63243.1 - 5.3e-06 26.4 4.1 0.0015 18.6 0.5 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAK63243.1 - 7.5e-05 22.5 9.3 0.024 14.5 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 GAK63243.1 - 0.0074 16.0 0.0 2.4 8.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAK63243.1 - 0.11 12.5 2.3 4.9 7.2 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 GAK63243.1 - 0.18 11.9 15.3 0.25 11.4 1.6 5.3 3 2 1 5 5 5 0 Tetratricopeptide repeat Sugar_tr PF00083.19 GAK63244.1 - 1.4e-111 373.3 25.8 1.9e-111 372.8 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Asp PF00026.18 GAK63244.1 - 1.6e-27 96.6 0.0 2.1e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease MFS_1 PF07690.11 GAK63244.1 - 3.3e-22 78.6 40.3 2.3e-15 56.1 7.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.22 GAK63244.1 - 6e-08 32.5 0.1 1.2e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TAXi_N PF14543.1 GAK63244.1 - 0.0011 18.9 0.0 0.0055 16.6 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Lactamase_B_2 PF12706.2 GAK63244.1 - 0.002 17.6 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain gag-asp_proteas PF13975.1 GAK63244.1 - 0.027 14.2 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ABC_membrane PF00664.18 GAK63245.1 - 3e-67 226.9 15.5 6.9e-38 130.6 2.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAK63245.1 - 1.5e-60 203.4 0.0 4e-30 104.9 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAK63245.1 - 3.3e-13 49.3 0.0 8.5e-06 25.1 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAK63245.1 - 1.4e-09 38.3 0.0 0.018 15.0 0.0 4.2 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 GAK63245.1 - 7.7e-09 34.6 0.0 0.0034 16.0 0.0 3.3 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 GAK63245.1 - 9.4e-09 36.1 0.0 0.0034 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAK63245.1 - 1.1e-08 34.5 1.0 0.0011 18.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAK63245.1 - 1.9e-08 33.6 0.0 0.00052 19.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAK63245.1 - 3.1e-07 30.5 0.6 0.0033 17.5 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 GAK63245.1 - 3.7e-07 30.2 0.9 0.036 14.0 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 GAK63245.1 - 2.3e-06 27.9 0.0 0.013 15.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 GAK63245.1 - 6.9e-06 25.5 0.0 0.057 12.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 GAK63245.1 - 1.7e-05 25.2 0.3 0.0034 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAK63245.1 - 0.00021 21.1 0.0 0.1 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 GAK63245.1 - 0.00037 20.3 1.6 0.72 9.8 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAK63245.1 - 0.004 16.6 2.0 1.5 8.1 0.0 3.4 4 0 0 4 4 4 1 AAA-like domain MobB PF03205.9 GAK63245.1 - 0.0049 16.5 0.1 1.5 8.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAK63245.1 - 0.0096 15.8 0.0 0.24 11.2 0.0 3.1 4 0 0 4 4 4 1 AAA domain DUF3987 PF13148.1 GAK63245.1 - 0.023 13.2 0.4 0.1 11.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.18 GAK63245.1 - 0.023 14.6 0.0 2.3 8.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 GAK63245.1 - 0.026 14.3 0.3 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 GAK63245.1 - 0.029 13.4 0.0 1.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 GAK63245.1 - 0.063 13.4 0.2 5.5 7.2 0.0 3.0 2 1 1 3 3 3 0 RNA helicase AAA_5 PF07728.9 GAK63245.1 - 0.072 12.8 0.0 2.2 8.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 GAK63245.1 - 0.14 12.3 0.0 15 5.8 0.0 3.3 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.7 GAK63245.1 - 0.21 10.6 0.0 3 6.8 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region eIF-5_eIF-2B PF01873.12 GAK63246.1 - 3.7e-47 159.0 0.6 5.3e-47 158.5 0.4 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 GAK63246.1 - 0.059 12.6 0.2 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF3359 PF11839.3 GAK63246.1 - 0.066 13.5 3.7 0.17 12.2 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) Zn-ribbon_8 PF09723.5 GAK63246.1 - 0.084 12.8 1.3 0.17 11.8 0.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain ATP-synt PF00231.14 GAK63247.1 - 2.7e-64 217.3 9.3 7.5e-61 206.0 3.5 2.1 2 0 0 2 2 2 2 ATP synthase LysM PF01476.15 GAK63249.1 - 0.00067 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain SNF2_N PF00176.18 GAK63250.1 - 3.4e-67 226.3 0.1 5.1e-67 225.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 GAK63250.1 - 4.1e-28 97.5 2.8 4.7e-28 97.3 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 GAK63250.1 - 1.1e-20 73.0 3.4 1.4e-13 50.2 0.0 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 GAK63250.1 - 1.2e-14 53.8 0.0 3e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK63250.1 - 5.5e-07 29.5 0.0 3.1e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAK63250.1 - 3.6e-05 23.3 0.0 8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 GAK63251.1 - 7e-09 35.2 9.8 7e-09 35.2 6.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 GAK63251.1 - 2.1e-07 30.5 2.9 2.1e-07 30.5 2.0 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 GAK63251.1 - 4.2e-07 29.6 14.5 7.2e-06 25.7 5.7 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 GAK63251.1 - 2.3e-06 27.5 12.5 7.1e-06 25.9 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAK63251.1 - 3.8e-06 26.6 12.6 5.6e-06 26.1 6.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAK63251.1 - 4.1e-06 26.4 13.9 9.9e-06 25.1 6.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 GAK63251.1 - 7e-05 22.2 7.5 0.0002 20.7 2.1 2.6 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 GAK63251.1 - 9.3e-05 22.0 9.8 0.00039 20.0 4.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 GAK63251.1 - 0.00012 21.5 1.3 0.00022 20.6 0.0 2.3 3 0 0 3 3 3 1 SAP domain zf-Apc11 PF12861.2 GAK63251.1 - 0.00054 19.7 4.6 0.0013 18.5 1.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.1 GAK63251.1 - 0.003 17.1 0.1 0.003 17.1 0.1 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zinc_ribbon_5 PF13719.1 GAK63251.1 - 0.015 14.8 5.7 0.19 11.3 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-MIZ PF02891.15 GAK63251.1 - 0.033 13.7 9.9 0.16 11.4 4.8 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zinc_ribbon_4 PF13717.1 GAK63251.1 - 0.042 13.5 6.0 0.62 9.8 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-rbx1 PF12678.2 GAK63251.1 - 0.043 13.9 8.3 0.16 12.0 2.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger Cys_rich_KTR PF14205.1 GAK63251.1 - 0.045 13.2 1.2 4.1 6.9 0.3 2.6 2 0 0 2 2 2 0 Cysteine-rich KTR zf-RING_UBOX PF13445.1 GAK63251.1 - 0.088 12.5 9.6 0.095 12.4 4.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.7 GAK63251.1 - 0.19 11.8 6.4 0.18 11.9 0.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 GAK63251.1 - 0.25 10.9 9.9 0.34 10.5 4.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_4 PF13894.1 GAK63251.1 - 0.28 11.5 0.1 0.28 11.5 0.1 3.9 3 1 0 3 3 2 0 C2H2-type zinc finger TipAS PF07739.8 GAK63251.1 - 0.99 9.7 0.0 0.99 9.7 0.0 2.6 3 0 0 3 3 2 0 TipAS antibiotic-recognition domain Tannase PF07519.6 GAK63254.1 - 8.1e-113 377.6 1.1 1e-112 377.3 0.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Pollen_allerg_2 PF01620.11 GAK63254.1 - 0.025 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) Peptidase_S9 PF00326.16 GAK63254.1 - 0.055 12.6 1.5 1.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_11 PF00457.12 GAK63256.1 - 5.2e-59 198.6 20.3 6.2e-59 198.4 14.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 HopJ PF08888.6 GAK63256.1 - 0.011 15.6 0.8 0.026 14.5 0.4 1.8 1 1 1 2 2 2 0 HopJ type III effector protein MFS_1 PF07690.11 GAK63258.1 - 7.4e-21 74.2 22.0 7.4e-21 74.2 15.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK63258.1 - 4.5e-05 22.2 11.1 9.4e-05 21.1 1.4 3.4 2 2 1 3 3 3 2 Sugar (and other) transporter DUF4191 PF13829.1 GAK63258.1 - 0.019 14.0 5.2 0.028 13.5 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4492 PF14899.1 GAK63258.1 - 1.5 8.3 4.7 0.2 11.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Zn_clus PF00172.13 GAK63259.1 - 1.1e-08 34.8 8.8 2.1e-08 33.9 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK63259.1 - 0.0016 17.3 1.0 0.4 9.5 0.0 2.7 2 1 1 3 3 3 2 Fungal specific transcription factor domain Peptidase_S15 PF02129.13 GAK63260.1 - 4e-39 134.6 2.7 1.9e-33 116.0 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAK63260.1 - 2.8e-25 89.4 0.0 4.1e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 GAK63260.1 - 5.3e-07 29.7 0.0 1.5e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1479 PF07350.7 GAK63261.1 - 4.4e-07 28.7 0.0 0.055 11.9 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) PhyH PF05721.8 GAK63261.1 - 2.4e-05 24.5 0.0 9e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 GAK63261.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.14 GAK63262.1 - 2.4e-24 86.0 0.0 6.5e-24 84.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 GAK63262.1 - 3.8e-06 25.9 0.0 6.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 GAK63262.1 - 0.001 18.8 0.2 0.0054 16.5 0.0 2.3 2 2 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 GAK63262.1 - 0.002 17.1 0.1 0.12 11.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK63262.1 - 0.0053 16.7 0.2 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK63262.1 - 0.012 15.5 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK63262.1 - 0.015 15.6 0.3 0.039 14.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK63262.1 - 0.017 15.2 0.0 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAK63262.1 - 0.24 10.1 1.1 0.29 9.9 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Dynactin_p62 PF05502.8 GAK63263.1 - 8.2e-124 414.0 10.7 1.2e-123 413.4 7.4 1.2 1 0 0 1 1 1 1 Dynactin p62 family Nop14 PF04147.7 GAK63263.1 - 0.22 9.3 7.8 0.34 8.7 5.4 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 GAK63263.1 - 1 8.5 11.4 0.48 9.6 3.9 2.2 2 0 0 2 2 2 0 SDA1 Nucleoplasmin PF03066.10 GAK63263.1 - 1.3 8.5 6.8 2.4 7.6 4.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin polyprenyl_synt PF00348.12 GAK63264.1 - 9.6e-74 247.5 0.0 1.1e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YtzH PF14165.1 GAK63264.1 - 0.067 13.4 0.1 0.39 10.9 0.0 2.2 2 1 0 2 2 2 0 YtzH-like protein MCM PF00493.18 GAK63265.1 - 3.2e-139 463.3 1.2 4.1e-139 463.0 0.1 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM2_N PF12619.3 GAK63265.1 - 8.1e-33 113.6 26.0 8.1e-33 113.6 18.0 2.8 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 GAK63265.1 - 4e-18 66.0 0.0 8.2e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAK63265.1 - 1.3e-08 34.2 0.0 3.8e-07 29.4 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAK63265.1 - 1.9e-06 27.6 0.0 4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAK63265.1 - 2e-05 24.2 0.2 0.0003 20.3 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAK63265.1 - 0.0073 15.7 0.1 0.065 12.7 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 GAK63265.1 - 0.07 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rsa3 PF14615.1 GAK63266.1 - 3.6e-07 29.3 0.0 1.3e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Ribosome-assembly protein 3 Ribosomal_L20 PF00453.13 GAK63266.1 - 0.42 10.5 3.2 4 7.3 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein L20 Fungal_trans PF04082.13 GAK63267.1 - 6.2e-24 84.2 0.1 1.1e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAK63267.1 - 6e-09 35.7 7.8 0.00029 20.9 2.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK63267.1 - 4.7e-07 29.6 7.3 0.0026 17.9 2.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAK63267.1 - 0.0005 20.2 2.1 0.28 11.5 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-BED PF02892.10 GAK63267.1 - 0.00085 19.0 0.6 0.00085 19.0 0.4 2.1 2 0 0 2 2 2 1 BED zinc finger zf-Di19 PF05605.7 GAK63267.1 - 0.006 16.6 0.7 0.013 15.5 0.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding SprT-like PF10263.4 GAK63267.1 - 0.021 14.5 0.2 1.5 8.4 0.2 2.4 2 0 0 2 2 2 0 SprT-like family zf-C2H2_jaz PF12171.3 GAK63267.1 - 0.27 11.4 5.4 1.3 9.2 1.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAK63267.1 - 2.3 8.2 4.8 21 5.1 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Epimerase PF01370.16 GAK63268.1 - 4.1e-18 65.6 0.0 5.4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK63268.1 - 4.8e-06 25.4 0.0 6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAK63268.1 - 8.9e-06 24.7 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAK63268.1 - 1.2e-05 24.3 0.0 0.00061 18.7 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAK63268.1 - 0.00032 20.6 0.0 0.00076 19.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAK63268.1 - 0.047 12.5 0.0 0.3 9.9 0.0 2.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 GAK63269.1 - 2.6e-34 118.5 27.4 2.6e-34 118.5 19.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 GAK63269.1 - 0.011 14.9 3.6 0.67 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) Pkinase PF00069.20 GAK63270.1 - 1.9e-52 178.0 0.0 2.5e-46 157.9 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63270.1 - 1.4e-26 93.1 0.8 5.9e-22 77.9 0.0 3.5 4 0 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.1 GAK63270.1 - 2.6e-05 23.3 0.0 0.17 10.8 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Cyto_heme_lyase PF01265.12 GAK63272.1 - 9.7e-71 238.3 0.7 1.5e-70 237.7 0.3 1.4 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF607 PF04678.8 GAK63273.1 - 5.7e-42 143.6 0.0 1.4e-41 142.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF607 UbiA PF01040.13 GAK63273.1 - 1e-29 103.5 17.9 1e-29 103.5 12.4 2.5 2 1 0 2 2 2 1 UbiA prenyltransferase family Brr6_like_C_C PF10104.4 GAK63275.1 - 7.8e-42 141.9 0.2 1e-41 141.6 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.1 GAK63275.1 - 8.4 6.7 9.5 4.5 7.6 4.8 1.9 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Y_phosphatase2 PF03162.8 GAK63276.1 - 3.1e-25 88.4 0.0 2.8e-16 59.2 0.0 2.3 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 GAK63276.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AIP3 PF03915.8 GAK63277.1 - 2e-108 363.0 1.1 2e-108 363.0 0.8 2.0 2 0 0 2 2 2 1 Actin interacting protein 3 DUF2315 PF10231.4 GAK63277.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Fib_alpha PF08702.5 GAK63277.1 - 1.4 9.0 8.2 31 4.6 0.2 3.8 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF383 PF04063.9 GAK63278.1 - 1.9e-76 255.9 0.0 3.4e-76 255.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 GAK63278.1 - 4.3e-19 67.8 0.1 8.2e-19 66.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Zn_clus PF00172.13 GAK63279.1 - 1.7e-09 37.4 10.2 3.9e-09 36.2 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK63279.1 - 0.00062 18.7 0.3 0.0011 17.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_box PF00505.14 GAK63280.1 - 5.7e-10 39.3 4.6 7.2e-09 35.7 3.2 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box DNA_pol_B PF00136.16 GAK63281.1 - 1.3e-147 492.3 2.8 1.9e-147 491.8 2.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 GAK63281.1 - 1.1e-90 303.8 0.0 1.9e-90 303.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 GAK63281.1 - 4e-23 81.2 8.2 9.3e-23 80.0 5.7 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 GAK63281.1 - 0.001 17.7 0.8 0.0075 14.9 0.0 2.4 2 1 1 3 3 3 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 GAK63281.1 - 0.021 14.6 0.2 0.086 12.6 0.1 2.2 1 1 0 1 1 1 0 RNase_H superfamily Flavoprotein PF02441.14 GAK63281.1 - 0.098 12.3 0.3 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Flavoprotein zf-RING-like PF08746.6 GAK63281.1 - 2.4 8.2 9.3 0.059 13.3 0.7 2.6 2 0 0 2 2 2 0 RING-like domain AMP-binding PF00501.23 GAK63282.1 - 3.1e-81 272.9 0.0 3.8e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK63282.1 - 3.2e-11 44.0 0.1 1.2e-10 42.1 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 GAK63282.1 - 0.0018 16.8 0.0 0.16 10.4 0.0 2.2 2 0 0 2 2 2 2 GH3 auxin-responsive promoter HK PF02110.10 GAK63282.1 - 0.03 13.5 0.4 0.091 11.9 0.0 1.8 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Nol1_Nop2_Fmu PF01189.12 GAK63283.1 - 1.9e-94 316.2 0.0 2.6e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 GAK63283.1 - 6.6e-05 22.5 0.0 0.00023 20.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 GAK63283.1 - 0.00061 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 GAK63283.1 - 0.002 18.1 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 GAK63283.1 - 0.0056 16.2 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 GAK63283.1 - 0.042 14.4 0.4 0.17 12.4 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain DUF3564 PF12087.3 GAK63283.1 - 0.084 12.4 0.2 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) DUF938 PF06080.7 GAK63283.1 - 0.089 12.3 0.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) MTS PF05175.9 GAK63283.1 - 0.11 11.8 0.0 0.95 8.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Acyl-CoA_dh_1 PF00441.19 GAK63284.1 - 1.1e-31 109.9 0.3 1.8e-31 109.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAK63284.1 - 1.1e-16 60.0 0.8 2.4e-16 58.9 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 GAK63284.1 - 3.1e-16 58.9 0.0 6.6e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 GAK63284.1 - 2.2e-10 41.1 0.0 1.6e-09 38.3 0.0 2.6 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAK63284.1 - 1.2e-06 28.8 0.0 3.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 GAK63284.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PXA PF02194.10 GAK63285.1 - 9.8e-21 74.1 0.2 2.5e-20 72.8 0.1 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 GAK63285.1 - 2.1e-07 30.9 0.0 5.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal DUF3505 PF12013.3 GAK63285.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) MGC-24 PF05283.6 GAK63285.1 - 3 7.6 12.0 12 5.6 8.3 2.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) EIF_2_alpha PF07541.7 GAK63286.1 - 4.2e-41 139.2 0.3 9.4e-41 138.1 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 GAK63286.1 - 1.2e-13 50.9 1.2 2.8e-13 49.7 0.3 2.1 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.4 GAK63286.1 - 0.0085 16.0 0.1 0.022 14.6 0.1 1.9 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 NRDE-2 PF08424.5 GAK63287.1 - 4e-29 101.5 0.1 1.1e-27 96.8 0.0 2.8 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference Ank_2 PF12796.2 GAK63287.1 - 4.1e-06 27.0 0.1 1.4e-05 25.2 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAK63287.1 - 1e-05 25.0 4.9 0.0047 16.6 0.0 4.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 GAK63287.1 - 3.3e-05 24.2 0.2 0.00012 22.4 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAK63287.1 - 0.00023 21.3 4.4 0.041 14.1 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK63287.1 - 0.0024 17.9 0.3 5.2 7.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Carn_acyltransf PF00755.15 GAK63291.1 - 1.5e-137 459.2 0.0 2.6e-137 458.4 0.0 1.4 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Trehalase PF01204.13 GAK63292.1 - 2.3e-172 574.2 0.1 3.1e-172 573.7 0.1 1.1 1 0 0 1 1 1 1 Trehalase GST_N_2 PF13409.1 GAK63292.1 - 8.1e-16 57.7 0.1 1.3e-14 53.9 0.0 2.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Trehalase_Ca-bi PF07492.6 GAK63292.1 - 6.6e-14 50.9 0.1 1.2e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GST_C_2 PF13410.1 GAK63292.1 - 4.7e-13 48.8 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAK63292.1 - 2.1e-06 27.6 0.3 8.5e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAK63292.1 - 0.071 13.5 0.2 0.42 11.1 0.0 2.4 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain RabGAP-TBC PF00566.13 GAK63293.1 - 6.6e-52 176.0 0.0 9.3e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CPSF73-100_C PF11718.3 GAK63294.1 - 2.4e-46 157.8 1.0 1.1e-45 155.6 0.5 2.1 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 GAK63294.1 - 7.5e-30 103.4 0.0 1.7e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 GAK63294.1 - 1.1e-17 64.3 1.2 2.1e-17 63.4 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAK63294.1 - 5.1e-11 42.4 1.9 5.1e-11 42.4 1.3 2.5 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.7 GAK63294.1 - 1.2e-10 40.9 0.2 2.3e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 GAK63294.1 - 8.9e-08 31.9 0.8 1.9e-07 30.9 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain MRP_L53 PF10780.4 GAK63295.1 - 0.028 14.3 0.3 0.068 13.1 0.2 1.8 1 1 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 DUF2454 PF10521.4 GAK63296.1 - 1.7e-11 43.6 0.0 1.1e-10 41.0 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) tRNA-synt_1d PF00750.14 GAK63297.1 - 6.7e-84 281.7 1.3 8.7e-84 281.3 0.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 GAK63297.1 - 6.2e-22 77.7 0.0 1.7e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain FlxA PF14282.1 GAK63298.1 - 0.0022 17.9 0.6 0.0022 17.9 0.4 3.9 5 0 0 5 5 5 1 FlxA-like protein DUF972 PF06156.8 GAK63298.1 - 0.77 10.1 18.5 4.9 7.5 1.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 GAK63298.1 - 6.3 6.3 24.2 8.1 5.9 2.8 2.4 2 0 0 2 2 2 0 IncA protein FNIP_N PF14636.1 GAK63299.1 - 0.15 12.5 1.5 0.26 11.7 1.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus ArabFuran-catal PF09206.6 GAK63300.1 - 1.6e-137 457.8 20.2 1.8e-137 457.6 14.0 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic F-box-like PF12937.2 GAK63301.1 - 0.073 12.8 0.2 0.22 11.2 0.1 1.9 1 1 0 1 1 1 0 F-box-like Spc97_Spc98 PF04130.8 GAK63302.1 - 1.3e-109 367.0 0.0 1.6e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DPBB_1 PF03330.13 GAK63302.1 - 0.12 12.4 0.0 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DEK_C PF08766.6 GAK63303.1 - 3e-06 26.8 0.5 8.8e-06 25.4 0.4 1.8 1 1 0 1 1 1 1 DEK C terminal domain Sugar_tr PF00083.19 GAK63304.1 - 1.6e-97 326.9 23.0 1.8e-97 326.7 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK63304.1 - 2.4e-20 72.5 28.2 2.4e-19 69.2 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_4 PF12799.2 GAK63306.1 - 3e-37 125.6 34.2 2.5e-10 39.7 2.5 6.4 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) WD40 PF00400.27 GAK63306.1 - 1.3e-28 97.7 7.7 1.7e-06 27.6 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat LRR_8 PF13855.1 GAK63306.1 - 9e-21 73.3 26.9 5.5e-08 32.4 4.0 5.1 2 1 4 6 6 6 6 Leucine rich repeat LRR_6 PF13516.1 GAK63306.1 - 2.5e-11 42.4 20.4 0.23 11.6 0.2 9.6 7 2 2 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.28 GAK63306.1 - 2.4e-09 35.9 31.0 0.12 12.4 0.2 10.1 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_7 PF13504.1 GAK63306.1 - 8.6e-09 34.1 20.1 0.73 10.2 0.1 9.1 8 1 0 8 8 8 1 Leucine rich repeat PQQ_2 PF13360.1 GAK63306.1 - 9.8e-08 31.7 0.8 3.4e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 PQQ-like domain LRR_9 PF14580.1 GAK63306.1 - 4.1e-07 29.7 10.0 6.1e-05 22.6 0.6 3.3 1 1 3 4 4 4 4 Leucine-rich repeat PQQ PF01011.16 GAK63306.1 - 0.042 13.4 1.8 7.4 6.2 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat LysM PF01476.15 GAK63306.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 LysM domain BESS PF02944.15 GAK63306.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 BESS motif PQQ_3 PF13570.1 GAK63306.1 - 0.18 12.1 0.1 0.18 12.1 0.1 4.5 5 0 0 5 5 4 0 PQQ-like domain Baculo_IE-1 PF05290.6 GAK63306.1 - 0.87 9.3 1.6 1.7 8.3 1.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FA_hydroxylase PF04116.8 GAK63307.1 - 2.4e-14 53.7 18.3 2.4e-14 53.7 12.7 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M16 PF00675.15 GAK63308.1 - 4.8e-23 81.5 2.3 3.6e-22 78.7 0.3 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAK63308.1 - 5.4e-13 49.0 0.1 3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Sad1_UNC PF07738.8 GAK63309.1 - 2.5e-08 33.8 0.0 5.3e-06 26.2 0.0 2.4 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal Phage_min_cap2 PF06152.6 GAK63309.1 - 0.0041 16.1 1.2 0.0063 15.5 0.8 1.2 1 0 0 1 1 1 1 Phage minor capsid protein 2 ATP_bind_1 PF03029.12 GAK63310.1 - 2.9e-76 256.1 0.3 7.9e-69 231.8 0.0 2.9 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 GAK63310.1 - 1.6e-06 27.6 0.5 1.5e-05 24.5 0.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 GAK63310.1 - 7e-06 25.5 0.0 2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 GAK63310.1 - 8.4e-05 22.6 0.0 0.00094 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAK63310.1 - 0.00051 20.1 0.0 0.0018 18.3 0.0 2.0 3 0 0 3 3 1 1 AAA domain AAA_17 PF13207.1 GAK63310.1 - 0.00086 20.1 0.0 0.0041 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAK63310.1 - 0.00093 19.1 0.0 0.0029 17.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK63310.1 - 0.0011 18.2 0.0 0.0042 16.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_10 PF12846.2 GAK63310.1 - 0.0015 18.0 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 GAK63310.1 - 0.0023 17.3 0.3 0.056 12.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 GAK63310.1 - 0.0036 16.9 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ArgK PF03308.11 GAK63310.1 - 0.0039 16.0 0.0 0.19 10.4 0.0 2.3 2 0 0 2 2 2 1 ArgK protein DUF87 PF01935.12 GAK63310.1 - 0.0057 16.4 1.0 0.18 11.6 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 GAK63310.1 - 0.011 15.5 0.2 0.011 15.5 0.2 2.7 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 GAK63310.1 - 0.012 15.8 0.1 0.044 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 GAK63310.1 - 0.013 14.9 0.0 1.3 8.4 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 GAK63310.1 - 0.014 14.8 0.0 0.59 9.5 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain G-alpha PF00503.15 GAK63310.1 - 0.028 13.1 0.2 2.1 6.9 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit RNA_helicase PF00910.17 GAK63310.1 - 0.034 14.3 0.0 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 GAK63310.1 - 0.063 12.4 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.13 GAK63310.1 - 0.072 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin T2SE PF00437.15 GAK63310.1 - 0.081 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 GAK63310.1 - 0.087 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 GAK63310.1 - 0.099 11.8 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PPV_E1_C PF00519.12 GAK63310.1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase KAP_NTPase PF07693.9 GAK63310.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 GAK63310.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3987 PF13148.1 GAK63310.1 - 0.45 9.0 3.9 3.2 6.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Zn_clus PF00172.13 GAK63311.1 - 6.8e-07 29.0 9.7 1.2e-06 28.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UMP1 PF05348.6 GAK63312.1 - 1.6e-22 79.8 0.2 2e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 rRNA_proc-arch PF13234.1 GAK63313.1 - 9.9e-95 316.7 0.0 1.5e-94 316.1 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 GAK63313.1 - 4.2e-59 198.8 0.9 1.5e-58 197.0 0.6 2.0 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAK63313.1 - 7.7e-22 77.5 0.0 4.8e-21 74.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK63313.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 GAK63313.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 GAK63313.1 - 0.095 12.5 0.0 1 9.1 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HAMP PF00672.20 GAK63313.1 - 0.13 12.4 1.0 8.4 6.6 0.1 2.6 2 0 0 2 2 2 0 HAMP domain DUF1510 PF07423.6 GAK63313.1 - 0.38 10.0 6.0 0.82 9.0 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-F_leu_zip PF10473.4 GAK63313.1 - 1.3 8.9 9.2 0.047 13.5 0.4 2.6 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 5_nucleotid_C PF02872.13 GAK63314.1 - 1.6e-26 93.1 0.0 9.4e-21 74.4 0.0 2.5 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 GAK63314.1 - 2.7e-09 36.7 0.9 1.5e-08 34.2 0.6 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAK63314.1 - 0.00077 19.3 0.1 0.0026 17.5 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Syntaxin-6_N PF09177.6 GAK63315.1 - 4e-20 72.0 2.6 5.5e-20 71.5 0.0 2.5 3 0 0 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 GAK63315.1 - 4.3e-10 39.1 2.9 4.3e-10 39.1 2.0 2.1 2 0 0 2 2 2 1 SNARE domain HSBP1 PF06825.7 GAK63316.1 - 3.8e-14 51.9 0.3 4.9e-14 51.6 0.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.7 GAK63316.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemagglutinin PF00509.13 GAK63316.1 - 0.048 11.7 0.0 0.059 11.5 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin UPF0184 PF03670.8 GAK63316.1 - 0.072 13.2 0.1 0.2 11.8 0.1 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) FlaC_arch PF05377.6 GAK63316.1 - 0.082 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MDMPI_N PF11716.3 GAK63316.1 - 0.093 13.1 4.0 0.12 12.8 2.8 1.2 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DELLA PF12041.3 GAK63316.1 - 0.1 12.3 1.3 0.83 9.3 0.1 2.3 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal YbgS PF13985.1 GAK63316.1 - 8.9 6.2 9.1 11 5.8 6.3 1.3 1 1 0 1 1 1 0 YbgS-like protein PPTA PF01239.17 GAK63317.1 - 2.1e-28 96.4 21.5 4e-07 29.0 0.1 6.0 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 GAK63317.1 - 0.0077 16.3 0.1 0.58 10.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3136 PF11334.3 GAK63317.1 - 0.037 13.4 0.3 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) BolA PF01722.13 GAK63318.1 - 1.2e-25 89.2 0.2 2.5e-25 88.2 0.2 1.5 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L9_N PF01281.14 GAK63318.1 - 3.1e-10 39.1 0.0 6e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain polyprenyl_synt PF00348.12 GAK63319.1 - 4.6e-40 137.1 0.7 1e-20 73.6 0.0 4.1 3 1 0 3 3 3 3 Polyprenyl synthetase DUF718 PF05336.8 GAK63320.1 - 1.2e-16 60.3 0.0 1.4e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Pkinase PF00069.20 GAK63321.1 - 7.4e-59 198.9 0.0 4.7e-39 134.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63321.1 - 4.3e-25 88.2 0.0 4.7e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 GAK63321.1 - 3.4e-09 36.6 0.0 7.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 GAK63321.1 - 1.4e-07 30.8 0.4 6e-06 25.4 0.0 2.6 3 0 0 3 3 3 1 Kinase-like PAS_9 PF13426.1 GAK63321.1 - 0.0033 17.7 0.0 0.0085 16.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 GAK63321.1 - 0.016 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_3 PF08447.6 GAK63321.1 - 0.035 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 GAK63321.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Herpes_UL6 PF01763.11 GAK63321.1 - 2.6 6.1 0.0 5.4 5.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like FAM91_C PF14648.1 GAK63321.1 - 3 6.5 0.0 7.9 5.1 0.0 1.6 2 0 0 2 2 2 0 FAM91 C-terminus Gly_transf_sug PF04488.10 GAK63322.1 - 1.2e-20 73.7 0.0 2.4e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 GAK63322.1 - 0.03 12.8 1.8 0.09 11.2 0.2 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Mito_carr PF00153.22 GAK63323.1 - 5e-82 269.7 0.1 1.3e-27 95.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.16 GAK63324.1 - 2.6e-93 313.3 0.0 3.4e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 Amidase ERG4_ERG24 PF01222.12 GAK63325.1 - 2.3e-124 415.2 20.8 2.6e-124 415.0 14.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ribosomal_L29e PF01779.12 GAK63328.1 - 1.5e-21 75.9 6.5 3.5e-21 74.7 4.5 1.7 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF1237 PF06824.6 GAK63329.1 - 1.1e-155 518.4 0.0 1.3e-155 518.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) PHD PF00628.24 GAK63330.1 - 6.7e-12 44.9 16.1 2.1e-07 30.5 2.0 3.8 4 0 0 4 4 4 2 PHD-finger zf-PHD-like PF15446.1 GAK63330.1 - 2.8 7.1 4.1 5 6.3 0.9 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 GAK63330.1 - 5.4 7.2 5.9 0.96 9.6 1.0 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Vps51 PF08700.6 GAK63331.1 - 3.8e-13 49.0 0.6 1.2e-12 47.5 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Pro_isomerase PF00160.16 GAK63332.1 - 4e-51 173.2 0.0 4.5e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Histone PF00125.19 GAK63333.1 - 7.3e-26 90.0 0.0 9.2e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAK63333.1 - 1.1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAK63334.1 - 6.1e-22 77.5 0.4 1e-21 76.8 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAK63334.1 - 1.3e-05 25.1 1.4 1.4e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 GAK63334.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 GAK63334.1 - 0.082 12.3 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 GAK63334.1 - 0.094 13.2 0.3 0.18 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Snf7 PF03357.16 GAK63335.1 - 3.7e-30 104.5 20.4 3.7e-30 104.5 14.1 1.4 1 1 0 1 1 1 1 Snf7 ACT_5 PF13710.1 GAK63335.1 - 0.041 13.7 1.5 0.11 12.3 0.2 2.2 2 0 0 2 2 2 0 ACT domain Eno-Rase_FAD_bd PF07055.7 GAK63335.1 - 0.1 12.5 1.0 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain MIP PF00230.15 GAK63338.1 - 3.6e-47 160.7 7.9 4.4e-47 160.4 5.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein PPI_Ypi1 PF07491.6 GAK63339.1 - 1e-24 85.9 6.0 1e-23 82.6 4.2 2.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor TATR PF03430.8 GAK63339.1 - 0.064 11.8 4.3 0.071 11.7 3.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator eIF3_subunit PF08597.5 GAK63339.1 - 0.28 10.7 7.9 0.36 10.3 5.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Sigma70_ner PF04546.8 GAK63339.1 - 1.5 8.4 5.9 2.1 7.9 4.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 GAK63339.1 - 1.9 6.4 11.7 2.4 6.0 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 GAK63340.1 - 2.5e-26 92.3 0.0 8.1e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63340.1 - 1.5e-13 50.4 0.0 6.6e-13 48.3 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK63340.1 - 0.021 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HrpE PF06188.7 GAK63340.1 - 0.079 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E zf-RING_2 PF13639.1 GAK63341.1 - 4.6e-05 23.1 4.7 4.6e-05 23.1 3.3 1.7 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 GAK63341.1 - 6.4e-05 22.3 0.4 0.00012 21.4 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.3 GAK63341.1 - 0.0018 18.1 3.2 0.0037 17.1 2.2 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 GAK63341.1 - 0.0067 16.2 1.2 0.017 14.9 0.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 GAK63341.1 - 0.013 15.2 4.5 0.015 15.0 2.1 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.2 GAK63341.1 - 0.014 15.4 0.6 0.029 14.4 0.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger RINGv PF12906.2 GAK63341.1 - 0.21 11.6 5.3 0.42 10.6 3.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 GAK63341.1 - 7.1 6.7 7.9 1.6 8.8 3.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Laminin_II PF06009.7 GAK63342.1 - 0.19 11.4 5.8 0.29 10.8 1.1 2.9 3 0 0 3 3 3 0 Laminin Domain II TPR_MLP1_2 PF07926.7 GAK63342.1 - 0.67 9.7 9.8 0.34 10.6 3.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 GAK63342.1 - 1 7.9 8.5 0.089 11.4 2.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.1 GAK63342.1 - 4 6.3 11.9 6.8 5.5 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 GAK63342.1 - 5.4 5.3 7.6 18 3.6 5.2 1.7 1 1 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 GAK63342.1 - 5.9 6.9 11.0 1 9.3 4.0 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UDP-g_GGTase PF06427.6 GAK63344.1 - 1.4e-55 187.9 0.0 2.8e-55 186.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 GAK63344.1 - 2.1e-08 33.8 0.0 3.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DPBB_1 PF03330.13 GAK63346.1 - 2.8e-10 40.0 0.0 9.9e-10 38.2 0.0 2.0 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pkinase PF00069.20 GAK63347.1 - 3e-62 210.1 0.0 4.8e-62 209.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63347.1 - 2.7e-36 124.9 0.0 2.1e-34 118.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK63347.1 - 9e-05 21.5 0.0 0.0025 16.8 0.0 2.5 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.17 GAK63347.1 - 0.0068 15.7 0.1 0.071 12.4 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.6 GAK63347.1 - 0.019 13.8 0.1 0.054 12.3 0.1 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.18 GAK63347.1 - 0.046 13.4 0.1 0.19 11.4 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family GST_N_2 PF13409.1 GAK63348.1 - 1.9e-19 69.3 0.0 3.4e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAK63348.1 - 2.2e-14 53.0 0.1 6.4e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAK63348.1 - 0.0031 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Y_phosphatase3C PF13348.1 GAK63348.1 - 0.035 14.2 0.3 0.094 12.8 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region GST_N_3 PF13417.1 GAK63348.1 - 0.05 13.8 0.2 0.33 11.2 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RasGEF PF00617.14 GAK63349.1 - 2.5e-53 180.5 0.0 4.2e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAK63349.1 - 3.9e-25 87.9 0.0 7.8e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.12 GAK63349.1 - 2.8e-14 52.3 0.1 6e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAK63349.1 - 4.1e-14 51.8 0.1 8.1e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAK63349.1 - 1e-12 47.2 0.0 1.9e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain 2-oxoacid_dh PF00198.18 GAK63350.1 - 3.1e-77 258.9 0.1 4.5e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAK63350.1 - 5.3e-20 70.8 2.3 9.6e-20 70.0 1.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 GAK63350.1 - 1.1e-05 25.0 0.5 0.0023 17.5 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 GAK63350.1 - 0.00018 21.7 0.2 0.75 10.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RebB PF11747.3 GAK63350.1 - 0.00024 20.9 1.2 0.00024 20.9 0.8 2.1 2 0 0 2 2 2 1 Killing trait HlyD_2 PF12700.2 GAK63350.1 - 0.00067 18.9 9.8 0.0039 16.3 4.8 2.3 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 GAK63350.1 - 0.00087 18.9 0.7 0.0019 17.8 0.5 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein MIP-T3 PF10243.4 GAK63350.1 - 0.012 14.0 22.3 0.018 13.5 15.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RnfC_N PF13375.1 GAK63350.1 - 0.087 12.5 0.7 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain SGT1 PF07093.6 GAK63350.1 - 0.18 10.1 13.1 0.24 9.7 9.1 1.1 1 0 0 1 1 1 0 SGT1 protein Macoilin PF09726.4 GAK63350.1 - 6 5.0 14.8 7.5 4.6 10.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF508 PF04370.7 GAK63350.1 - 8 6.0 8.7 16 5.1 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Apt1 PF10351.4 GAK63350.1 - 9.5 4.9 14.6 15 4.3 10.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain HOOK PF05622.7 GAK63353.1 - 0.15 9.8 17.6 1.3 6.7 12.2 2.2 1 1 0 1 1 1 0 HOOK protein DUF948 PF06103.6 GAK63353.1 - 0.18 11.7 0.0 0.75 9.6 0.0 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 GAK63353.1 - 0.62 9.5 5.6 0.14 11.7 0.5 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bap31 PF05529.7 GAK63353.1 - 4.1 6.8 3.2 15 4.9 2.1 2.1 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF972 PF06156.8 GAK63353.1 - 4.5 7.6 7.1 9.3 6.6 1.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) zf-Di19 PF05605.7 GAK63354.1 - 2.8e-07 30.5 14.3 0.0014 18.6 0.0 4.6 5 1 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding Cys_rich_CPXG PF14255.1 GAK63354.1 - 0.02 14.6 8.9 0.46 10.3 0.0 4.3 4 0 0 4 4 4 0 Cysteine-rich CPXCG DUF2024 PF09630.5 GAK63354.1 - 1.6 8.5 3.8 22 4.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) zf-C2H2_4 PF13894.1 GAK63354.1 - 6.4 7.3 20.5 34 5.0 0.2 5.8 5 0 0 5 5 5 0 C2H2-type zinc finger Fork_head PF00250.13 GAK63355.1 - 3.1e-20 71.9 0.0 5.2e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Fork head domain Amidohydro_2 PF04909.9 GAK63356.1 - 9.6e-10 38.4 0.1 1.4e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 GAK63356.1 - 2.3e-06 27.8 0.5 4e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Amidohydrolase FUN14 PF04930.10 GAK63357.1 - 6.3e-23 80.9 1.1 7.3e-23 80.7 0.2 1.5 2 0 0 2 2 2 1 FUN14 family LSM PF01423.17 GAK63360.1 - 4.6e-14 51.7 0.0 8.2e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 LSM domain PRELI PF04707.9 GAK63360.1 - 4.7e-13 48.9 2.5 0.0009 18.8 0.0 4.2 4 0 0 4 4 4 4 PRELI-like family Bromodomain PF00439.20 GAK63362.1 - 1.2e-14 53.9 0.0 2.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain MFS_1 PF07690.11 GAK63363.1 - 1.8e-24 86.1 12.2 4.3e-24 84.8 7.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIID_30kDa PF03540.8 GAK63364.1 - 3.9e-26 90.6 0.0 7.2e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 GAK63364.1 - 1.5e-06 27.8 0.0 0.0003 20.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain Ribosomal_60s PF00428.14 GAK63364.1 - 0.065 13.6 0.1 0.065 13.6 0.0 4.1 4 1 0 4 4 4 0 60s Acidic ribosomal protein F-112 PF09645.5 GAK63364.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 F-112 protein tRNA-synt_2d PF01409.15 GAK63366.1 - 8e-87 290.5 0.0 1.1e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 GAK63366.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 GAK63366.1 - 5e-05 22.2 0.1 0.00098 17.9 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) IBN_N PF03810.14 GAK63367.1 - 2.2e-08 33.8 2.0 9.9e-06 25.3 1.0 3.6 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAK63367.1 - 0.0096 15.8 0.0 0.049 13.5 0.0 2.3 1 0 0 1 1 1 1 Exportin 1-like protein G-patch PF01585.18 GAK63368.1 - 5e-11 42.2 1.3 1.6e-08 34.2 0.5 2.5 2 0 0 2 2 2 2 G-patch domain G-patch_2 PF12656.2 GAK63368.1 - 0.00037 20.2 0.6 0.048 13.5 0.1 2.7 2 0 0 2 2 2 2 DExH-box splicing factor binding site Acetyltransf_1 PF00583.19 GAK63369.1 - 1.3e-11 44.3 0.0 2.3e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAK63369.1 - 1.9e-05 24.7 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAK63369.1 - 0.00071 19.6 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK63369.1 - 0.001 18.7 0.0 0.0089 15.7 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Alpha_E3_glycop PF01563.11 GAK63369.1 - 0.09 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Peptidase_M55 PF04951.8 GAK63369.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 D-aminopeptidase Acetyltransf_CG PF14542.1 GAK63369.1 - 0.14 12.0 0.0 0.93 9.4 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Med20 PF08612.6 GAK63370.1 - 0.025 13.7 0.0 3.1 6.8 0.0 2.7 2 1 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Nop25 PF09805.4 GAK63370.1 - 1.2 9.1 12.9 5.7 7.0 0.5 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF410 PF04190.8 GAK63371.1 - 5e-23 81.9 0.0 4.8e-22 78.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TPR_11 PF13414.1 GAK63371.1 - 0.11 12.1 1.1 0.64 9.7 0.5 2.3 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 GAK63371.1 - 6.9 7.5 9.6 0.64 10.8 0.7 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat PROCN PF08083.6 GAK63372.1 - 3.1e-192 638.5 1.9 4.6e-192 637.9 1.3 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 GAK63372.1 - 2.5e-122 406.5 0.6 4.3e-122 405.7 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 GAK63372.1 - 1e-85 284.9 0.5 3.2e-85 283.3 0.4 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 GAK63372.1 - 2.7e-77 257.5 3.3 6.9e-77 256.2 2.3 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 GAK63372.1 - 4.2e-60 201.2 0.0 8.8e-60 200.2 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 GAK63372.1 - 3.1e-44 148.7 0.3 7.2e-44 147.5 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 GAK63372.1 - 2.6e-33 114.3 0.0 5.4e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 GAK63372.1 - 0.0025 17.5 0.0 0.0074 16.0 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease APC_CDC26 PF10471.4 GAK63374.1 - 2.3e-05 25.0 5.2 0.00014 22.5 3.6 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 SelP_N PF04592.9 GAK63374.1 - 1 8.6 4.7 1.1 8.5 3.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HrpB7 PF09486.5 GAK63375.1 - 0.018 15.0 8.4 0.52 10.2 1.0 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) SNARE PF05739.14 GAK63375.1 - 0.042 13.5 0.2 0.074 12.7 0.2 1.4 1 0 0 1 1 1 0 SNARE domain IncA PF04156.9 GAK63375.1 - 0.05 13.2 0.9 0.071 12.6 0.6 1.3 1 0 0 1 1 1 0 IncA protein WEMBL PF05701.6 GAK63375.1 - 0.066 11.6 1.7 0.11 10.9 1.2 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light BAG PF02179.11 GAK63375.1 - 0.087 12.9 0.4 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 BAG domain CCDC-167 PF15188.1 GAK63375.1 - 0.088 12.7 1.4 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Dak2 PF02734.12 GAK63375.1 - 0.12 12.0 1.0 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 DAK2 domain Tropomyosin PF00261.15 GAK63375.1 - 0.13 11.3 1.3 0.22 10.6 0.9 1.3 1 0 0 1 1 1 0 Tropomyosin DivIVA PF05103.8 GAK63375.1 - 0.47 10.5 2.1 0.89 9.6 0.3 1.9 2 0 0 2 2 2 0 DivIVA protein Pyr_redox_3 PF13738.1 GAK63376.1 - 1.5e-15 57.8 0.0 6.9e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAK63376.1 - 2.1e-12 46.0 0.0 1.4e-06 26.8 0.0 3.7 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 GAK63376.1 - 1.6e-07 31.2 0.1 4.8e-06 26.4 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAK63376.1 - 4.8e-07 29.0 0.2 1.3e-05 24.3 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAK63376.1 - 8e-06 25.8 0.0 0.00048 20.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK63376.1 - 0.0026 17.7 0.1 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK63376.1 - 0.019 13.8 0.6 0.067 12.0 0.1 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase JAB PF01398.16 GAK63377.1 - 9.3e-34 115.6 0.0 1.7e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAK63377.1 - 1.3e-28 99.3 2.1 1.3e-28 99.3 1.4 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 GAK63377.1 - 5.6e-07 29.0 0.0 9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Arf PF00025.16 GAK63378.1 - 7e-36 123.0 0.0 3.8e-25 88.1 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 GAK63378.1 - 9.7e-14 51.0 0.0 4.4e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 GAK63378.1 - 4.1e-08 32.6 0.0 8.8e-08 31.5 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 GAK63378.1 - 4.4e-08 33.6 0.0 1.2e-07 32.2 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 GAK63378.1 - 5e-07 29.0 0.0 6.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAK63378.1 - 8.9e-06 24.6 0.1 1.6e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 GAK63378.1 - 3.7e-05 23.6 0.0 5.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAK63378.1 - 0.0011 18.8 0.0 0.12 12.1 0.2 2.2 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 GAK63378.1 - 0.038 13.4 0.1 5.8 6.2 0.0 2.7 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Vps52 PF04129.7 GAK63379.1 - 2.8e-34 118.5 0.0 2.5e-23 82.3 0.0 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family IncA PF04156.9 GAK63379.1 - 0.013 15.1 1.7 0.03 13.9 1.2 1.5 1 0 0 1 1 1 0 IncA protein Sec3_C PF09763.4 GAK63379.1 - 0.015 13.4 0.0 0.036 12.2 0.0 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec3 Kdo_hydroxy PF11004.3 GAK63379.1 - 0.02 13.9 0.0 0.056 12.4 0.0 1.7 2 0 0 2 2 2 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase FTA4 PF13093.1 GAK63379.1 - 0.032 13.6 3.9 1.3 8.4 0.6 2.3 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1057 PF06342.7 GAK63379.1 - 0.29 9.9 0.0 0.47 9.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Pkinase PF00069.20 GAK63380.1 - 1.9e-63 214.0 0.0 4.6e-63 212.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63380.1 - 1.6e-35 122.4 0.0 2.5e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK63380.1 - 0.00015 20.8 0.2 0.0013 17.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 GAK63380.1 - 0.0022 16.8 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIC1 PF07064.8 GAK63381.1 - 2.6e-70 236.8 0.0 6.8e-39 133.8 0.0 2.3 2 0 0 2 2 2 2 RIC1 WD40 PF00400.27 GAK63381.1 - 0.046 13.6 0.6 13 5.8 0.1 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat DEC-1_C PF04626.8 GAK63381.1 - 0.047 13.8 0.7 15 5.7 0.2 2.7 2 0 0 2 2 2 0 Dec-1 protein, C terminal region DUF914 PF06027.7 GAK63381.1 - 0.38 9.5 0.0 0.69 8.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) PQ-loop PF04193.9 GAK63382.1 - 8.4e-37 124.5 5.4 1.4e-19 69.3 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Sre PF03125.13 GAK63382.1 - 0.11 11.4 0.7 0.16 10.8 0.5 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor DUF740 PF05340.7 GAK63383.1 - 0.44 8.8 3.5 0.62 8.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) ECH PF00378.15 GAK63384.1 - 1.2e-16 60.5 0.2 2.4e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 GAK63384.1 - 1.5e-10 40.9 0.1 1.9e-09 37.3 0.0 2.7 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 GAK63384.1 - 5.5e-06 26.4 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.11 GAK63386.1 - 9.2e-35 119.9 25.8 9.2e-35 119.9 17.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily CIAPIN1 PF05093.8 GAK63388.1 - 7.3e-32 109.4 4.1 1.5e-31 108.4 2.9 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis WBS_methylT PF12589.3 GAK63389.1 - 8.1e-18 64.7 9.3 1.5e-17 63.8 6.5 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 GAK63389.1 - 5.3e-11 42.8 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK63389.1 - 3.8e-08 33.2 0.0 6.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK63389.1 - 3.9e-06 27.2 0.0 1.1e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK63389.1 - 6.5e-06 26.4 0.0 1.7e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK63389.1 - 8.5e-06 25.4 0.0 1.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK63389.1 - 1.5e-05 25.5 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK63389.1 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 GAK63389.1 - 0.0045 17.0 0.0 0.05 13.7 0.0 2.2 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.13 GAK63389.1 - 0.052 13.0 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 DNA methylase AFG1_ATPase PF03969.11 GAK63390.1 - 1.8e-53 181.6 8.2 1.8e-49 168.4 0.0 4.5 4 1 0 4 4 4 2 AFG1-like ATPase DnaJ PF00226.26 GAK63390.1 - 5.5e-20 70.8 0.3 1.9e-19 69.1 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain AAA_16 PF13191.1 GAK63390.1 - 6.2e-05 23.0 1.0 0.0032 17.4 0.0 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAK63390.1 - 0.005 16.9 0.0 0.42 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAK63390.1 - 0.15 12.2 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AIPR PF10592.4 GAK63390.1 - 0.3 10.3 1.0 0.53 9.5 0.7 1.3 1 0 0 1 1 1 0 AIPR protein GPI-anchored PF10342.4 GAK63392.1 - 2.6e-11 43.8 3.6 2.6e-11 43.8 2.5 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cna_B PF05738.8 GAK63392.1 - 0.095 12.4 0.0 0.095 12.4 0.0 2.0 3 0 0 3 3 3 0 Cna protein B-type domain Fungal_trans PF04082.13 GAK63393.1 - 2.7e-33 114.9 0.0 5.3e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK63393.1 - 2e-08 34.0 9.5 3.3e-08 33.2 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S9 PF00326.16 GAK63396.1 - 6.4e-41 139.9 0.4 1.7e-28 99.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family PIG-H PF10181.4 GAK63396.1 - 2.2e-12 46.4 0.0 3.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Abhydrolase_5 PF12695.2 GAK63396.1 - 2.1e-10 40.5 4.5 1.5e-06 28.0 0.1 3.0 2 1 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 GAK63396.1 - 4.6e-08 32.6 0.0 9e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAK63396.1 - 2e-05 24.4 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 GAK63396.1 - 3.9e-05 23.6 5.7 0.00021 21.2 0.1 3.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 GAK63396.1 - 0.0039 17.0 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 GAK63396.1 - 0.022 14.2 0.9 0.47 9.9 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.8 GAK63396.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Kinesin PF00225.18 GAK63397.1 - 2.9e-112 374.6 0.0 4.3e-112 374.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL6 PF01763.11 GAK63397.1 - 8.5e-05 20.9 4.3 8.5e-05 20.9 3.0 1.6 2 0 0 2 2 2 1 Herpesvirus UL6 like Atg14 PF10186.4 GAK63397.1 - 0.043 12.7 3.1 0.088 11.7 2.2 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PRAI PF00697.17 GAK63397.1 - 0.16 11.5 1.4 0.29 10.6 0.0 2.1 3 0 0 3 3 3 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase AAA_13 PF13166.1 GAK63397.1 - 0.4 9.0 5.0 0.74 8.1 3.5 1.3 1 0 0 1 1 1 0 AAA domain Filament PF00038.16 GAK63397.1 - 0.56 9.6 15.0 1.2 8.5 10.4 1.5 1 1 0 1 1 1 0 Intermediate filament protein DUF972 PF06156.8 GAK63397.1 - 1.1 9.5 5.0 2.8 8.3 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1515 PF07439.6 GAK63397.1 - 1.4 8.7 6.3 0.67 9.7 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) V_ATPase_I PF01496.14 GAK63397.1 - 2.2 6.0 4.2 3 5.5 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2630 PF10944.3 GAK63397.1 - 3 8.0 7.5 7.3 6.7 2.7 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) eRF1_1 PF03463.10 GAK63398.1 - 6.4e-56 187.5 0.0 9.2e-56 187.0 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 GAK63398.1 - 2.3e-23 82.6 0.0 4.5e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 GAK63398.1 - 2.6e-22 79.5 0.0 4.3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 L51_S25_CI-B8 PF05047.11 GAK63399.1 - 7.1e-14 51.2 0.0 9.6e-14 50.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RAI16-like PF10257.4 GAK63400.1 - 5.5e-66 222.9 0.0 9.1e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ATP12 PF07542.6 GAK63401.1 - 1.8e-37 127.9 0.0 2.8e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Pex24p PF06398.6 GAK63402.1 - 2.3e-22 79.3 7.7 2.3e-22 79.3 5.3 3.1 2 2 0 2 2 2 2 Integral peroxisomal membrane peroxin PIG-S PF10510.4 GAK63403.1 - 7.5e-112 374.6 3.0 2.7e-111 372.8 2.1 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Aldo_ket_red PF00248.16 GAK63404.1 - 3.6e-51 173.6 0.0 6.1e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.18 GAK63405.1 - 0.00016 21.4 0.9 0.00032 20.4 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 GAK63405.1 - 0.036 13.7 0.4 0.09 12.4 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle FUSC_2 PF13515.1 GAK63406.1 - 1.3e-22 80.0 4.9 1.3e-22 80.0 3.4 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 GAK63406.1 - 2e-17 62.9 5.7 1.5e-12 46.9 0.2 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 GAK63406.1 - 2.2e-12 46.2 3.8 2.2e-12 46.2 2.6 3.6 4 0 0 4 4 4 2 Fusaric acid resistance protein family DUF2421 PF10334.4 GAK63406.1 - 2e-09 37.4 0.0 4.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 GAK63406.1 - 0.00038 20.3 0.7 0.00038 20.3 0.5 2.9 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF939) DUF2422 PF10337.4 GAK63406.1 - 0.012 14.4 0.0 0.012 14.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2422) DUF1469 PF07332.6 GAK63406.1 - 4.2 7.1 11.9 0.2 11.3 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Zn_clus PF00172.13 GAK63407.1 - 0.00057 19.7 7.5 0.0016 18.2 5.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec39 PF08314.6 GAK63408.1 - 4.6e-43 147.1 0.0 7e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 TPR_7 PF13176.1 GAK63408.1 - 0.08 12.7 2.4 4 7.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Med21 PF11221.3 GAK63409.1 - 3.3e-12 46.5 4.0 4.8e-12 46.0 2.8 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF3422 PF11902.3 GAK63409.1 - 0.0074 15.2 1.1 0.01 14.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3422) Spc7 PF08317.6 GAK63409.1 - 0.012 14.3 2.1 0.019 13.6 1.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin_2 PF14523.1 GAK63409.1 - 0.023 14.7 0.5 0.036 14.1 0.3 1.3 1 0 0 1 1 1 0 Syntaxin-like protein LMP PF04778.7 GAK63409.1 - 0.11 12.2 0.3 0.69 9.6 0.2 1.9 1 1 1 2 2 2 0 LMP repeated region DUF1664 PF07889.7 GAK63409.1 - 0.16 11.7 1.7 0.31 10.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.6 GAK63409.1 - 2.4 8.0 5.8 0.68 9.7 0.8 2.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ICMT PF04140.9 GAK63410.1 - 1.2e-25 89.4 1.5 1.3e-25 89.4 0.2 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 GAK63410.1 - 1.2e-13 51.0 1.1 1.2e-13 51.0 0.8 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAK63410.1 - 0.00013 21.3 1.8 0.0002 20.7 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TRP PF06011.7 GAK63411.1 - 1.7e-72 244.3 7.5 2.7e-72 243.7 5.2 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF3808 PF10300.4 GAK63412.1 - 3.1e-82 276.6 0.4 7.1e-82 275.4 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Zn_clus PF00172.13 GAK63412.1 - 0.0043 16.9 11.6 0.0095 15.8 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LacY_symp PF01306.14 GAK63412.1 - 2.6 6.4 0.0 4.1 5.8 0.0 1.1 1 0 0 1 1 1 0 LacY proton/sugar symporter Ribosomal_S18 PF01084.15 GAK63413.1 - 3.5e-19 68.3 0.0 9e-19 67.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 Acetyltransf_2 PF00797.12 GAK63414.1 - 3.9e-24 85.5 0.4 2.6e-22 79.5 0.0 2.8 2 1 0 2 2 2 1 N-acetyltransferase WD40 PF00400.27 GAK63415.1 - 2e-08 33.7 16.7 0.037 13.9 0.5 4.3 3 1 0 3 3 3 3 WD domain, G-beta repeat PQQ_3 PF13570.1 GAK63415.1 - 0.00016 21.8 1.2 0.075 13.3 0.0 4.3 5 0 0 5 5 5 1 PQQ-like domain DUF4611 PF15387.1 GAK63415.1 - 0.84 9.8 3.4 1.7 8.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cactin_mid PF10312.4 GAK63416.1 - 9.7e-65 217.4 5.9 2.8e-64 215.9 4.1 1.8 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 GAK63416.1 - 8.8e-60 199.7 4.9 1.7e-59 198.8 3.4 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein eIF-5a PF01287.15 GAK63416.1 - 0.24 11.3 1.9 4.2 7.3 0.6 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold AD PF09793.4 GAK63417.1 - 1.9e-21 75.7 0.0 4.7e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain Patched PF02460.13 GAK63418.1 - 3.5e-61 207.1 1.1 2.7e-32 111.6 0.1 3.2 4 1 0 4 4 4 2 Patched family Sterol-sensing PF12349.3 GAK63418.1 - 4.6e-42 143.0 12.2 3.7e-21 75.1 0.3 3.5 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.9 GAK63418.1 - 0.0019 17.8 1.4 0.0036 16.9 1.0 1.4 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.14 GAK63418.1 - 0.019 12.3 0.4 0.028 11.8 0.3 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Endonuclease_NS PF01223.18 GAK63419.1 - 0.0022 17.6 0.0 0.48 10.0 0.0 2.4 2 0 0 2 2 2 2 DNA/RNA non-specific endonuclease CobD_Cbib PF03186.8 GAK63419.1 - 0.1 11.6 0.2 0.22 10.5 0.1 1.6 2 0 0 2 2 2 0 CobD/Cbib protein tRNA_anti-codon PF01336.20 GAK63421.1 - 0.052 13.4 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain CHZ PF09649.5 GAK63422.1 - 1.4e-11 43.4 0.2 1.4e-11 43.4 0.1 3.5 3 1 0 3 3 3 1 Histone chaperone domain CHZ Ebola_NP PF05505.7 GAK63422.1 - 4.9 5.0 15.1 5.4 4.9 10.5 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein RNA_pol_Rpb4 PF03874.11 GAK63423.1 - 1.1e-25 89.8 0.6 1.5e-25 89.4 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ecm29 PF13001.2 GAK63423.1 - 0.095 11.1 0.1 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser WD40 PF00400.27 GAK63424.1 - 2.8e-39 131.5 8.8 2e-09 36.9 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 GAK63424.1 - 3.9e-26 90.8 9.6 6.1e-26 90.2 6.7 1.3 1 0 0 1 1 1 1 Sof1-like domain Nucleoporin_N PF08801.6 GAK63424.1 - 0.0017 17.1 0.4 3.3 6.3 0.0 4.4 3 1 2 6 6 6 1 Nup133 N terminal like CBFB_NFYA PF02045.10 GAK63425.1 - 2e-27 95.4 11.4 2e-27 95.4 7.9 2.5 2 1 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ThuA PF06283.6 GAK63426.1 - 4.5e-41 140.9 0.0 6.5e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Trehalose utilisation DUF3446 PF11928.3 GAK63426.1 - 0.033 14.3 6.4 0.094 12.9 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Sporozoite_P67 PF05642.6 GAK63426.1 - 0.86 7.3 8.7 1.1 6.9 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Kelch_4 PF13418.1 GAK63427.1 - 1.6e-32 110.9 2.2 1.1e-06 28.2 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 GAK63427.1 - 4.1e-31 106.4 5.6 1.8e-07 31.1 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain DUF4110 PF13422.1 GAK63427.1 - 1.6e-22 79.1 0.1 1.6e-22 79.1 0.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.1 GAK63427.1 - 3.2e-19 68.4 2.3 2.2e-05 24.2 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 GAK63427.1 - 1.4e-18 66.1 6.8 0.00032 20.7 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 GAK63427.1 - 3.6e-13 48.8 2.5 0.00015 21.2 0.0 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 GAK63427.1 - 1.9e-12 46.3 0.7 0.015 15.0 0.0 5.2 6 0 0 6 6 6 3 Kelch motif BUD22 PF09073.5 GAK63427.1 - 0.00041 19.5 19.1 0.00041 19.5 13.3 2.4 2 0 0 2 2 2 1 BUD22 Pox_Ag35 PF03286.9 GAK63427.1 - 0.00085 18.9 8.5 0.00085 18.9 5.9 3.0 3 0 0 3 3 3 1 Pox virus Ag35 surface protein Adaptin_binding PF10199.4 GAK63427.1 - 0.017 15.3 0.7 0.017 15.3 0.5 3.6 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Acetyltransf_6 PF13480.1 GAK63427.1 - 0.067 13.1 2.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain S-antigen PF05756.6 GAK63427.1 - 5.8 6.9 10.7 3.3 7.7 0.6 2.9 2 0 0 2 2 2 0 S-antigen protein ECH PF00378.15 GAK63428.1 - 1.1e-19 70.5 0.0 1.2e-17 63.8 0.0 2.5 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family DUF1731 PF08338.6 GAK63428.1 - 0.026 14.0 0.3 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Myb_DNA-bind_2 PF08914.6 GAK63430.1 - 0.091 12.5 0.2 0.29 10.9 0.0 2.0 2 1 0 2 2 2 0 Rap1 Myb domain Actin PF00022.14 GAK63431.1 - 1.6e-132 441.6 0.0 2.1e-132 441.2 0.0 1.1 1 0 0 1 1 1 1 Actin DUF1077 PF06417.7 GAK63431.1 - 2.5e-45 152.8 0.7 5.2e-45 151.8 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1077) adh_short PF00106.20 GAK63431.1 - 6e-26 91.3 5.1 6e-26 91.3 3.5 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK63431.1 - 5e-22 78.8 0.0 8.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK63431.1 - 1.1e-11 44.7 2.9 1.1e-11 44.7 2.0 2.0 2 0 0 2 2 2 1 KR domain AhpC-TSA_2 PF13911.1 GAK63431.1 - 1.7e-11 44.0 0.0 9.2e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 GAK63431.1 - 0.015 14.7 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Redoxin Eno-Rase_NADH_b PF12242.3 GAK63431.1 - 0.023 14.4 3.7 0.029 14.1 0.9 2.2 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AhpC-TSA PF00578.16 GAK63431.1 - 0.11 12.1 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family DHQ_synthase PF01761.15 GAK63432.1 - 1.5e-49 168.3 0.0 1.9e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 GAK63432.1 - 8.5e-12 44.9 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cellulase-like PF12876.2 GAK63434.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Rad17 PF03215.10 GAK63435.1 - 2.7e-42 145.1 0.0 1.1e-41 143.1 0.0 2.0 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAK63435.1 - 0.058 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain IBN_N PF03810.14 GAK63436.1 - 1.7e-15 56.7 0.0 6.9e-15 54.7 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.5 GAK63436.1 - 1.3e-07 30.5 0.0 3.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 GAK63436.1 - 0.039 13.8 0.0 0.25 11.2 0.0 2.5 1 0 0 1 1 1 0 Exportin 1-like protein HEAT PF02985.17 GAK63436.1 - 0.056 13.5 1.1 8.2 6.8 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat Inhibitor_I9 PF05922.11 GAK63436.1 - 0.068 13.7 0.0 2.1 8.9 0.0 2.9 2 0 0 2 2 2 0 Peptidase inhibitor I9 Translin PF01997.11 GAK63437.1 - 1e-33 116.6 0.1 1.3e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 Translin family Myosin_tail_1 PF01576.14 GAK63437.1 - 0.11 10.1 2.9 0.16 9.6 2.0 1.1 1 0 0 1 1 1 0 Myosin tail Ribosomal_L1 PF00687.16 GAK63438.1 - 9e-52 175.5 0.0 1.3e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Motile_Sperm PF00635.21 GAK63439.1 - 6.2e-26 90.1 0.2 1e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF3348 PF11828.3 GAK63439.1 - 0.029 13.7 3.0 0.049 13.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Macoilin PF09726.4 GAK63439.1 - 0.69 8.1 2.6 0.8 7.9 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4336 PF14234.1 GAK63440.1 - 3.9e-08 32.8 0.1 0.076 12.1 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) Rap1-DNA-bind PF09197.5 GAK63440.1 - 0.028 14.9 0.1 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Rap1, DNA-binding ESX-1_EspG PF14011.1 GAK63441.1 - 0.0024 17.1 0.5 0.0026 17.0 0.4 1.1 1 0 0 1 1 1 1 EspG family Erythro-docking PF09277.6 GAK63441.1 - 0.092 12.4 0.4 0.31 10.7 0.4 1.9 2 0 0 2 2 2 0 Erythronolide synthase, docking ATPgrasp_Ter PF15632.1 GAK63442.1 - 0.0001 21.1 0.0 0.0015 17.3 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DUF3608 PF12257.3 GAK63443.1 - 2e-74 250.0 0.0 3.3e-74 249.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 GAK63443.1 - 3.8e-19 68.1 0.2 8.7e-19 67.0 0.2 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2 PF01569.16 GAK63444.1 - 4e-10 39.4 10.2 4e-10 39.4 7.1 2.1 2 2 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 GAK63444.1 - 3.8e-07 29.8 11.6 1.3e-06 28.1 8.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 GAK63444.1 - 9.5 6.5 15.1 0.051 13.8 3.2 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DUF4449 PF14613.1 GAK63445.1 - 2.4e-07 30.8 0.1 2.4e-07 30.8 0.0 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF4449) Katanin_con80 PF13925.1 GAK63445.1 - 0.036 13.7 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 con80 domain of Katanin DUF883 PF05957.8 GAK63445.1 - 0.21 11.9 40.8 0.87 10.0 0.3 6.9 4 1 3 7 7 7 0 Bacterial protein of unknown function (DUF883) Acetyltransf_1 PF00583.19 GAK63446.1 - 3.4e-14 52.6 0.4 5.5e-14 51.9 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAK63446.1 - 2e-09 37.0 0.1 3.5e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAK63446.1 - 1.3e-08 35.0 0.1 1.8e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAK63446.1 - 1.6e-06 28.0 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAK63446.1 - 2.4e-06 27.6 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAK63446.1 - 2.4e-06 27.7 0.0 3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAK63446.1 - 5.4e-05 23.0 0.1 8.2e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAK63446.1 - 0.00097 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Aminotran_1_2 PF00155.16 GAK63448.1 - 3.2e-33 115.1 0.0 7.2e-33 114.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAK63448.1 - 6.2e-05 22.2 0.0 9.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase TPR_11 PF13414.1 GAK63449.1 - 7.2e-22 76.8 6.0 1.1e-13 50.5 0.9 2.6 1 1 1 2 2 2 2 TPR repeat RPAP3_C PF13877.1 GAK63449.1 - 1.3e-11 44.2 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.23 GAK63449.1 - 1.8e-11 43.1 11.1 2.6e-05 23.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAK63449.1 - 1.6e-07 30.6 14.0 0.0036 17.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK63449.1 - 5.1e-06 26.9 1.8 5.1e-06 26.9 1.2 3.5 4 1 1 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAK63449.1 - 0.0014 18.5 0.6 0.74 9.7 0.0 2.5 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 GAK63449.1 - 0.0038 17.3 0.4 0.023 14.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAK63449.1 - 0.0058 16.9 7.7 2.7 8.3 1.8 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAK63449.1 - 0.006 16.4 1.0 0.014 15.2 0.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAK63449.1 - 2 9.2 11.5 2 9.2 1.4 4.3 2 1 3 5 5 5 0 Tetratricopeptide repeat FAM176 PF14851.1 GAK63450.1 - 3.1 7.4 7.6 1.8 8.2 0.1 2.1 2 0 0 2 2 2 0 FAM176 family DUF1682 PF07946.9 GAK63450.1 - 5.8 5.6 11.1 9.1 5.0 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Brix PF04427.13 GAK63453.1 - 3.7e-45 153.9 0.1 5.3e-45 153.4 0.1 1.2 1 0 0 1 1 1 1 Brix domain Ribosomal_L28 PF00830.14 GAK63454.1 - 6.8e-22 77.0 0.2 1.3e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L28 family PIN_4 PF13638.1 GAK63455.1 - 0.00018 21.5 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 PIN domain Sec23_trunk PF04811.10 GAK63456.1 - 1.6e-77 260.1 0.0 2.3e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAK63456.1 - 1.7e-35 120.5 0.2 3.1e-35 119.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAK63456.1 - 5.2e-31 107.0 0.0 9.3e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAK63456.1 - 6.1e-17 60.8 6.2 1.2e-16 59.9 4.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAK63456.1 - 9.8e-12 44.4 0.0 2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat DnaJ PF00226.26 GAK63457.1 - 8.1e-07 28.6 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 GAK63457.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Pam16 Glyco_transf_41 PF13844.1 GAK63458.1 - 5.5e-101 337.8 0.6 7.4e-47 159.3 0.0 4.1 2 1 1 4 4 4 4 Glycosyl transferase family 41 TPR_11 PF13414.1 GAK63458.1 - 6e-23 80.2 4.5 1.1e-09 37.7 0.1 4.7 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 GAK63458.1 - 3.3e-20 70.7 0.0 3.1e-05 23.3 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAK63458.1 - 3.1e-18 64.3 6.6 0.00015 21.7 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAK63458.1 - 2.5e-16 58.1 0.1 0.00093 18.9 0.0 6.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAK63458.1 - 5.3e-14 51.9 1.2 2e-06 27.6 0.0 4.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAK63458.1 - 1.7e-11 43.6 5.7 0.004 17.6 0.0 7.0 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAK63458.1 - 6.7e-11 41.1 0.0 0.0006 19.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAK63458.1 - 1e-10 41.1 4.0 0.012 15.4 0.0 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAK63458.1 - 4.3e-08 32.3 0.0 0.13 12.1 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAK63458.1 - 1.9e-07 31.2 0.1 0.013 15.7 0.1 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK63458.1 - 0.13 12.9 0.0 0.13 12.9 0.0 7.7 7 1 1 8 8 5 0 Tetratricopeptide repeat WD40 PF00400.27 GAK63459.1 - 1.1e-10 41.0 0.7 0.0043 16.8 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Citrate_synt PF00285.16 GAK63460.1 - 3.9e-100 335.0 0.0 4.7e-100 334.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 GAK63460.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 XH domain SNARE PF05739.14 GAK63461.1 - 2.1e-09 36.9 0.1 3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 GAK63461.1 - 0.00025 20.5 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4316 PF14195.1 GAK63461.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) DUF1664 PF07889.7 GAK63461.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DPBB_1 PF03330.13 GAK63462.1 - 2e-05 24.4 0.2 3.8e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 GAK63462.1 - 0.00071 19.2 1.3 0.0011 18.6 0.6 1.4 1 1 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 GAK63462.1 - 0.012 15.6 0.1 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Cerato-platanin TIM21 PF08294.6 GAK63463.1 - 4.4e-14 52.3 0.0 9.8e-11 41.5 0.0 2.6 2 0 0 2 2 2 2 TIM21 OapA PF04225.7 GAK63463.1 - 0.097 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain Yippee-Mis18 PF03226.9 GAK63464.1 - 2.3e-22 78.8 0.2 2.6e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Evr1_Alr PF04777.8 GAK63464.1 - 0.043 13.7 1.2 0.4 10.6 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Toxin_6 PF05453.7 GAK63464.1 - 0.062 13.5 0.5 2 8.7 0.1 2.3 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family Endonuclease_7 PF02945.10 GAK63464.1 - 0.08 12.6 2.2 0.39 10.4 1.5 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII BSP_II PF05432.6 GAK63466.1 - 0.011 15.0 1.4 0.017 14.4 1.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Destabilase PF05497.7 GAK63466.1 - 0.074 13.1 1.6 0.14 12.2 0.4 1.9 1 1 0 1 1 1 0 Destabilase Nucleoplasmin PF03066.10 GAK63466.1 - 0.12 11.9 1.0 0.16 11.4 0.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 GAK63466.1 - 0.12 12.6 3.3 0.2 11.9 2.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Str_synth PF03088.11 GAK63467.1 - 0.037 14.0 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Strictosidine synthase Arylesterase PF01731.15 GAK63467.1 - 0.068 13.1 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Arylesterase Ribosomal_L19e PF01280.15 GAK63468.1 - 1.9e-61 206.1 10.3 1.9e-61 206.1 7.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e Ribosomal_S27e PF01667.12 GAK63470.1 - 2.7e-27 94.0 4.5 4e-27 93.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 Drf_FH1 PF06346.7 GAK63470.1 - 0.013 14.9 3.3 0.023 14.2 2.3 1.4 1 0 0 1 1 1 0 Formin Homology Region 1 Mu-like_Com PF10122.4 GAK63470.1 - 0.11 11.5 2.8 1.5 7.9 0.1 3.0 2 1 1 3 3 3 0 Mu-like prophage protein Com zf-DHHC PF01529.15 GAK63471.1 - 6.2e-38 129.9 7.6 1.1e-37 129.0 5.3 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase QueC PF06508.8 GAK63471.1 - 1.2 8.3 4.2 1.9 7.6 2.9 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Longin PF13774.1 GAK63472.1 - 5.7e-16 57.8 0.0 1.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 GAK63472.1 - 2.7e-14 52.5 0.7 5e-14 51.6 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Herpes_teg_N PF04843.7 GAK63472.1 - 0.09 12.1 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region CENP-L PF13092.1 GAK63473.1 - 1.5e-09 37.8 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Glucan_synthase PF02364.10 GAK63474.1 - 0 1366.4 0.0 0 1366.0 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 GAK63474.1 - 1.9e-37 127.7 0.0 4.4e-37 126.5 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 GAK63477.1 - 1.4e-95 319.9 0.0 2.2e-95 319.2 0.0 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 GAK63477.1 - 2.4e-18 66.3 0.9 5.8e-18 65.1 0.6 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 GAK63477.1 - 7e-05 22.1 0.0 0.00028 20.1 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rhomboid PF01694.17 GAK63479.1 - 8.6e-31 106.9 13.5 8.6e-31 106.9 9.3 2.0 1 1 1 2 2 2 1 Rhomboid family DUF3382 PF11862.3 GAK63479.1 - 0.015 15.1 0.2 0.015 15.1 0.1 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) DUF1762 PF08574.5 GAK63480.1 - 1.9e-05 24.9 6.2 1.9e-05 24.9 4.3 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1762) Ras PF00071.17 GAK63481.1 - 1.8e-54 183.5 0.0 2e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK63481.1 - 2.7e-20 73.0 0.0 4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK63481.1 - 2e-07 30.3 0.0 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAK63481.1 - 0.00024 20.6 0.1 0.0029 17.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAK63481.1 - 0.00062 18.9 0.0 0.00077 18.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAK63481.1 - 0.0031 17.4 0.0 0.0062 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK63481.1 - 0.012 14.8 0.1 0.07 12.3 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 GAK63481.1 - 0.041 13.2 0.1 0.091 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 GAK63481.1 - 0.12 11.7 0.2 0.31 10.4 0.1 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-H2C2_2 PF13465.1 GAK63482.1 - 0.019 15.2 0.7 0.019 15.2 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_3 PF14369.1 GAK63482.1 - 0.034 14.1 0.3 0.074 13.0 0.2 1.6 1 0 0 1 1 1 0 zinc-finger zf-C2H2 PF00096.21 GAK63482.1 - 0.054 13.8 16.0 0.074 13.4 1.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAK63482.1 - 0.93 9.4 4.3 1.4 8.9 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAK63482.1 - 3.3 7.9 9.0 8.9 6.5 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Gly-zipper_YMGG PF13441.1 GAK63482.1 - 6.7 6.3 13.0 0.38 10.2 3.5 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF605 PF04652.11 GAK63483.1 - 5.7e-104 348.5 4.4 9.9e-104 347.7 3.0 1.4 1 1 0 1 1 1 1 Vta1 like PDDEXK_2 PF12784.2 GAK63483.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase MCM PF00493.18 GAK63484.1 - 1.3e-133 444.9 0.0 1.8e-133 444.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAK63484.1 - 2.5e-19 69.9 0.0 1.2e-18 67.7 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 GAK63484.1 - 5.7e-08 32.5 0.0 2.1e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAK63484.1 - 4.7e-07 29.1 0.0 0.00025 20.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAK63484.1 - 0.00041 19.9 0.1 0.028 14.0 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAK63484.1 - 0.0052 16.2 0.2 1.3 8.5 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain DSX_dimer PF08828.5 GAK63484.1 - 0.2 11.1 4.7 10 5.7 0.2 3.6 3 0 0 3 3 3 0 Doublesex dimerisation domain WD40 PF00400.27 GAK63485.1 - 3.5e-25 86.9 2.3 6.9e-06 25.7 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 GAK63485.1 - 1.6e-06 27.9 0.1 0.00013 21.6 0.1 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 GAK63485.1 - 0.00052 19.2 0.2 0.0024 17.0 0.0 2.0 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 GAK63485.1 - 0.0018 16.2 0.3 0.28 8.9 0.1 2.6 2 1 0 3 3 3 2 IKI3 family Apc4_WD40 PF12894.2 GAK63485.1 - 0.022 14.2 0.0 8.3 5.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3512 PF12024.3 GAK63486.1 - 2.7e-05 23.6 0.2 5.2e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) zf-CCCH PF00642.19 GAK63487.1 - 5.1e-17 61.1 15.2 6.4e-10 38.4 1.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAK63487.1 - 0.25 11.3 14.7 0.8 9.8 0.9 2.9 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type oligo_HPY PF08352.7 GAK63487.1 - 0.46 10.8 5.3 5.5 7.4 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region DUF2418 PF10332.4 GAK63488.1 - 5.8e-26 90.6 1.4 6.6e-26 90.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Cation_ATPase_C PF00689.16 GAK63488.1 - 0.17 11.3 2.9 0.29 10.6 2.0 1.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus ETS_PEA3_N PF04621.8 GAK63489.1 - 0.091 11.9 2.1 0.11 11.7 1.4 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Ras PF00071.17 GAK63490.1 - 6.1e-62 207.7 0.1 7.3e-62 207.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK63490.1 - 6e-20 71.9 0.0 8.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK63490.1 - 1.7e-12 46.9 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK63490.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK63490.1 - 2.2e-05 23.9 0.1 9.1e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAK63490.1 - 7.1e-05 22.9 0.0 0.00027 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 GAK63490.1 - 0.0024 17.0 0.1 0.0059 15.7 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAK63490.1 - 0.0028 16.8 0.0 0.0057 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 GAK63490.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 GAK63490.1 - 0.017 15.1 0.4 0.042 13.8 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 GAK63490.1 - 0.023 14.1 0.0 0.077 12.4 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 GAK63490.1 - 0.025 13.7 0.0 0.061 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAK63490.1 - 0.028 14.7 0.2 0.036 14.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 GAK63490.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAK63490.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 GAK63490.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 GAK63490.1 - 0.13 11.5 0.1 0.67 9.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Xpo1 PF08389.7 GAK63491.1 - 1.9e-22 79.7 0.0 5.9e-21 74.9 0.0 3.3 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 GAK63491.1 - 8.5e-05 22.3 0.3 0.00021 21.1 0.2 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain AAA PF00004.24 GAK63492.1 - 2.6e-41 140.9 0.0 4.8e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAK63492.1 - 1.3e-28 98.6 0.2 5e-28 96.7 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 GAK63492.1 - 2.7e-23 81.6 5.4 8.4e-23 80.0 3.8 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 GAK63492.1 - 1.4e-05 25.2 0.4 0.0019 18.3 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 GAK63492.1 - 4e-05 24.4 0.1 0.0002 22.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAK63492.1 - 4.3e-05 23.0 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 GAK63492.1 - 6e-05 21.9 0.3 0.00012 20.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 GAK63492.1 - 6.6e-05 22.8 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAK63492.1 - 6.9e-05 22.9 0.1 0.015 15.4 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.1 GAK63492.1 - 0.00012 21.9 0.4 0.00063 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAK63492.1 - 0.00013 21.1 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAK63492.1 - 0.00016 21.3 0.0 0.00055 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAK63492.1 - 0.0003 20.8 0.6 0.0068 16.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 GAK63492.1 - 0.00067 19.1 0.1 0.24 10.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 GAK63492.1 - 0.0013 18.7 0.0 0.0058 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAK63492.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 GAK63492.1 - 0.0093 15.1 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 GAK63492.1 - 0.014 14.5 0.1 0.48 9.4 0.1 2.5 1 1 0 1 1 1 0 Zeta toxin KaiC PF06745.8 GAK63492.1 - 0.015 14.4 0.0 4.7 6.2 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.1 GAK63492.1 - 0.03 13.8 0.4 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 GAK63492.1 - 0.042 12.6 0.5 2.5 6.7 0.0 2.7 3 0 0 3 3 3 0 AFG1-like ATPase PhoH PF02562.11 GAK63492.1 - 0.059 12.6 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 GAK63492.1 - 0.065 13.0 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 GAK63492.1 - 0.069 12.6 0.0 0.5 9.8 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 GAK63492.1 - 0.074 12.7 0.0 0.59 9.7 0.0 2.4 2 1 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 GAK63492.1 - 0.095 12.7 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps39_2 PF10367.4 GAK63493.1 - 2.2e-10 40.6 0.2 6.9e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 GAK63493.1 - 8.5e-05 22.5 0.1 0.00058 19.8 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 GAK63493.1 - 0.0035 16.8 0.0 0.014 14.8 0.0 2.0 2 1 0 2 2 2 1 CNH domain PQQ_3 PF13570.1 GAK63493.1 - 0.089 13.0 0.0 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain zf-C2H2_4 PF13894.1 GAK63494.1 - 1.9e-06 27.7 14.1 0.0021 18.2 1.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAK63494.1 - 4.1e-06 26.8 12.3 0.0026 17.9 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK63494.1 - 0.14 12.5 10.5 1.7 9.1 1.7 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Terminase_GpA PF05876.7 GAK63494.1 - 2 6.6 6.2 2.9 6.1 4.3 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-C2H2_jaz PF12171.3 GAK63494.1 - 3.8 7.7 11.6 0.72 10.0 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mito_carr PF00153.22 GAK63495.1 - 1e-58 195.0 1.9 9.4e-21 73.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Phage_coat PF09063.5 GAK63497.1 - 0.038 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Phage PP7 coat protein AUX_IAA PF02309.11 GAK63497.1 - 0.15 11.8 2.8 0.23 11.1 1.9 1.3 1 0 0 1 1 1 0 AUX/IAA family Inositol_P PF00459.20 GAK63498.1 - 2.2e-54 184.6 0.3 2.5e-53 181.1 0.2 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family LIM PF00412.17 GAK63499.1 - 1.9e-17 63.0 28.2 7.3e-11 41.9 1.7 4.2 4 0 0 4 4 4 3 LIM domain Pkinase PF00069.20 GAK63500.1 - 1.2e-67 227.8 0.0 1.6e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63500.1 - 4.1e-46 157.1 0.0 6e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK63500.1 - 2.4e-08 33.3 0.0 4e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 GAK63500.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras_bdg_2 PF14847.1 GAK63500.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 YrbL-PhoP_reg PF10707.4 GAK63500.1 - 0.99 8.7 0.0 1.8 7.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 GAK63500.1 - 1.7 7.3 0.0 2.8 6.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 KilA-N PF04383.8 GAK63502.1 - 0.00094 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain PCI PF01399.22 GAK63505.1 - 1.9e-05 24.8 0.0 4.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain Herpes_glycop_H PF02489.11 GAK63506.1 - 2.9 5.7 0.0 4.5 5.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein H Sugar_tr PF00083.19 GAK63508.1 - 3.8e-97 325.6 25.0 4.5e-97 325.4 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK63508.1 - 8.1e-17 60.9 53.1 5.9e-16 58.1 19.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAK63508.1 - 0.12 12.4 0.2 0.12 12.4 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) MFS_3 PF05977.8 GAK63508.1 - 3 5.8 12.1 0.92 7.5 5.4 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector LIP PF03583.9 GAK63510.1 - 1.7e-69 234.2 0.2 2.3e-69 233.8 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_8 PF06259.7 GAK63510.1 - 0.018 14.5 0.4 6.1 6.3 0.0 3.2 3 0 0 3 3 3 0 Alpha/beta hydrolase Peptidase_S9 PF00326.16 GAK63510.1 - 0.11 11.7 1.3 1.5 8.0 0.1 2.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF2413 PF10310.4 GAK63511.1 - 3.5e-81 273.3 4.8 4.7e-81 272.8 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Sugar_tr PF00083.19 GAK63512.1 - 8.5e-56 189.4 18.9 8.1e-55 186.1 13.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK63512.1 - 6.2e-14 51.4 35.3 6.2e-14 51.4 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtB PF09489.5 GAK63512.1 - 0.21 11.5 1.0 1.4 8.8 0.7 2.6 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) DUF3437 PF11919.3 GAK63513.1 - 6.7e-32 109.0 0.0 6e-31 106.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 GAK63513.1 - 0.00015 21.5 0.1 0.0015 18.4 0.1 2.9 2 0 0 2 2 2 1 HEAT repeat DUF1546 PF07571.8 GAK63513.1 - 0.0021 18.1 0.2 0.096 12.8 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1546) Arm PF00514.18 GAK63513.1 - 0.0022 17.7 0.1 0.011 15.5 0.1 2.3 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAK63513.1 - 0.0049 17.1 2.7 0.017 15.4 0.0 3.2 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 GAK63513.1 - 0.044 14.3 2.1 0.1 13.1 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAK63513.1 - 0.089 13.1 0.1 0.49 10.8 0.1 2.3 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Cut8_C PF08559.5 GAK63514.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Cut8 six-helix bundle PEP-utilisers_N PF05524.8 GAK63514.1 - 0.033 13.9 0.3 0.079 12.7 0.1 1.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Pkinase PF00069.20 GAK63516.1 - 2.5e-73 246.4 0.0 2.9e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63516.1 - 1.8e-35 122.2 0.0 2.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK63516.1 - 0.0085 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK63516.1 - 0.039 13.6 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAK63516.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Utp12 PF04003.7 GAK63517.1 - 6.4e-12 45.3 0.3 1.8e-11 43.8 0.2 1.8 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 GAK63517.1 - 3.1 7.8 11.2 0.17 11.7 0.7 3.3 3 1 0 3 3 3 0 WD domain, G-beta repeat CoA_binding PF02629.14 GAK63518.1 - 1.5e-27 95.9 0.5 4.2e-27 94.5 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 GAK63518.1 - 4e-19 68.7 0.0 2.6e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 GAK63518.1 - 2.8e-06 26.9 0.0 8.5e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 GAK63518.1 - 5.9e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 GAK63518.1 - 0.0044 17.5 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HNH_3 PF13392.1 GAK63519.1 - 1.7e-05 24.1 0.3 1.7e-05 24.1 0.2 1.7 2 0 0 2 2 2 1 HNH endonuclease MMR_HSR1 PF01926.18 GAK63521.1 - 1.1e-16 60.8 0.0 2.2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 GAK63521.1 - 4.5e-15 55.2 0.1 1.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain TAP_C PF03943.8 GAK63521.1 - 7.8e-14 50.8 0.2 2.1e-13 49.4 0.1 1.8 1 0 0 1 1 1 1 TAP C-terminal domain FeoB_N PF02421.13 GAK63521.1 - 4.5e-11 42.2 0.0 7.9e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B LRR_4 PF12799.2 GAK63521.1 - 3.2e-06 26.6 7.7 0.00013 21.4 1.2 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Miro PF08477.8 GAK63521.1 - 1.2e-05 25.7 0.0 2.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein LRR_8 PF13855.1 GAK63521.1 - 0.0016 18.1 1.0 0.0074 16.0 0.4 2.4 3 0 0 3 3 3 1 Leucine rich repeat Dynamin_N PF00350.18 GAK63521.1 - 0.026 14.3 0.4 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 Dynamin family LRR_9 PF14580.1 GAK63521.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat AIG1 PF04548.11 GAK63521.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family CBS PF00571.23 GAK63522.1 - 2.5e-36 123.2 9.2 1.3e-08 34.4 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 GAK63522.1 - 2.2e-06 27.2 0.0 4.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PB1 domain DUF4288 PF14119.1 GAK63522.1 - 0.055 13.6 0.0 8.1 6.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) DUF2380 PF09533.5 GAK63522.1 - 0.073 12.4 0.8 14 5.0 0.0 2.8 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) NYN PF01936.13 GAK63522.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 NYN domain DUF1682 PF07946.9 GAK63522.1 - 9.5 4.9 7.9 20 3.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Zn_clus PF00172.13 GAK63523.1 - 3.4e-06 26.8 12.0 6.2e-06 26.0 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCAS2 PF05700.6 GAK63525.1 - 2e-61 207.2 1.0 2.6e-61 206.9 0.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Erythro-docking PF09277.6 GAK63525.1 - 0.0018 17.9 1.1 0.49 10.1 0.3 2.5 2 0 0 2 2 2 2 Erythronolide synthase, docking EzrA PF06160.7 GAK63525.1 - 0.0025 16.1 2.7 0.003 15.8 1.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF3027 PF11228.3 GAK63525.1 - 0.1 12.2 1.7 0.54 9.9 1.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3027) Enkurin PF13864.1 GAK63525.1 - 0.16 12.1 8.2 0.26 11.5 5.2 1.7 2 0 0 2 2 2 0 Calmodulin-binding NPV_P10 PF05531.7 GAK63525.1 - 1.1 9.5 6.2 6.1 7.1 0.9 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 GAK63525.1 - 2.5 7.7 11.2 4 7.1 7.2 1.7 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 GAK63525.1 - 3.4 7.2 10.5 5.8 6.4 7.3 1.4 1 0 0 1 1 1 0 IncA protein Complex1_30kDa PF00329.14 GAK63526.1 - 3.4e-35 120.3 0.0 4.9e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Arm PF00514.18 GAK63527.1 - 9.3e-09 34.8 23.4 3.1e-05 23.6 0.2 8.4 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAK63527.1 - 1.4e-05 24.8 20.9 0.15 12.2 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 GAK63527.1 - 0.032 14.7 24.3 2.1 8.9 0.0 8.4 8 1 0 8 8 8 0 HEAT-like repeat MCM PF00493.18 GAK63528.1 - 1.6e-128 428.1 0.0 2.2e-128 427.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAK63528.1 - 3.1e-22 79.3 0.1 8.5e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAK63528.1 - 6.3e-08 32.0 0.0 8.8e-07 28.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAK63528.1 - 0.0048 16.5 0.0 0.0096 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAK63528.1 - 0.0072 15.8 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain BTV_NS2 PF04514.7 GAK63528.1 - 0.085 11.7 1.3 0.55 9.0 0.9 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 DUF500 PF04366.7 GAK63529.1 - 1.1e-37 128.3 0.6 1.1e-37 128.3 0.4 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 GAK63529.1 - 6.9e-12 44.5 0.1 1.4e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAK63529.1 - 1e-10 40.9 0.0 1.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAK63529.1 - 2.2e-10 39.9 0.0 4.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rad60-SLD PF11976.3 GAK63529.1 - 0.23 11.1 0.0 0.49 10.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Cache_3 PF14827.1 GAK63530.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase UvrD_C PF13361.1 GAK63532.1 - 1.7e-76 257.9 0.0 2.4e-45 155.5 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 GAK63532.1 - 9.2e-70 235.4 0.1 9.2e-70 235.4 0.1 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 GAK63532.1 - 7.2e-13 48.5 0.0 2.3e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 GAK63532.1 - 1.8e-10 40.4 0.2 6.3e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain HNH_3 PF13392.1 GAK63532.1 - 1.6e-06 27.4 0.1 4e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease AAA_11 PF13086.1 GAK63532.1 - 1.6e-05 24.6 0.1 1.6e-05 24.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain Vhr1 PF04001.8 GAK63532.1 - 0.085 12.7 0.2 25 4.8 0.1 2.9 2 0 0 2 2 2 0 Transcription factor Vhr1 PALP PF00291.20 GAK63533.1 - 2.5e-48 164.8 4.0 3.1e-48 164.5 2.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU PF00009.22 GAK63534.1 - 1.2e-49 168.2 0.0 2.4e-49 167.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 GAK63534.1 - 7.6e-22 76.9 0.0 1.7e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 GAK63534.1 - 6e-17 61.2 0.3 9.5e-15 54.2 0.2 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAK63534.1 - 5.9e-08 32.7 0.0 2e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAK63534.1 - 0.0025 17.7 0.0 0.0073 16.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 GAK63534.1 - 0.086 12.4 0.1 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 Elongation factor G, domain IV HCO3_cotransp PF00955.16 GAK63535.1 - 8.3e-42 143.4 10.4 1.3e-23 83.5 1.2 3.1 1 1 1 2 2 2 2 HCO3- transporter family FHA PF00498.21 GAK63536.1 - 0.033 14.2 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 FHA domain Nop14 PF04147.7 GAK63536.1 - 8.9 4.0 9.1 14 3.4 6.3 1.3 1 0 0 1 1 1 0 Nop14-like family EcKinase PF02958.15 GAK63537.1 - 0.18 10.9 2.6 0.39 9.8 1.8 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase EcsC PF12787.2 GAK63537.1 - 0.33 10.2 7.5 0.077 12.3 0.7 2.7 2 0 0 2 2 2 0 EcsC protein family RAP1 PF07218.6 GAK63537.1 - 1.1 7.2 2.7 1.8 6.5 1.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AMP-binding PF00501.23 GAK63538.1 - 5e-77 259.0 0.0 6.8e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAK63538.1 - 2e-64 216.8 0.0 3.3e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAK63538.1 - 2.8e-14 53.1 0.0 8.2e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAK63538.1 - 5.3e-09 36.8 0.0 2.8e-08 34.5 0.0 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 GAK63538.1 - 6.4e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.15 GAK63538.1 - 0.00036 19.4 0.2 0.0049 15.7 0.1 2.2 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.14 GAK63538.1 - 0.019 13.6 0.0 2.3 6.8 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1688 PF07958.6 GAK63541.1 - 1.6e-163 544.1 0.0 1.8e-163 543.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2419 PF10343.4 GAK63541.1 - 0.14 11.4 0.0 0.35 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2419) ABC2_membrane PF01061.19 GAK63542.1 - 1.5e-34 119.0 16.3 1.5e-34 119.0 11.3 2.2 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.22 GAK63542.1 - 5.7e-24 84.9 0.0 8.9e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAK63542.1 - 2.1e-06 27.8 0.0 0.024 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAK63542.1 - 7.1e-05 21.9 23.7 0.00018 20.7 16.4 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 GAK63542.1 - 0.00056 19.3 0.0 0.007 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAK63542.1 - 0.0078 15.7 0.1 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAK63542.1 - 0.013 16.2 0.0 0.028 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAK63542.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAK63542.1 - 0.032 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 GAK63542.1 - 0.033 13.3 0.0 0.091 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAK63542.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 GAK63542.1 - 0.068 12.6 0.0 0.15 11.4 0.0 1.5 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAK63542.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAK63542.1 - 0.11 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAK63542.1 - 0.12 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 GAK63542.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 GAK63542.1 - 0.18 10.8 0.0 3.2 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 GAK63542.1 - 0.28 10.8 0.2 0.51 9.9 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 GAK63542.1 - 0.32 10.2 0.0 0.57 9.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_23 PF13476.1 GAK63542.1 - 0.35 11.1 0.1 0.56 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain hEGF PF12661.2 GAK63542.1 - 0.4 10.8 24.7 0.5 10.5 3.0 4.5 4 0 0 4 4 3 0 Human growth factor-like EGF Hemerythrin PF01814.18 GAK63544.1 - 1.4e-14 54.3 0.9 1.4e-11 44.7 0.2 2.0 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LRR_4 PF12799.2 GAK63545.1 - 2e-26 91.0 5.3 7.5e-07 28.6 0.1 7.9 6 2 5 11 11 11 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK63545.1 - 1.1e-23 82.6 13.5 5.6e-08 32.4 0.4 6.1 5 1 1 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 GAK63545.1 - 6.6e-11 40.6 18.1 0.35 11.0 0.1 11.1 10 3 2 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 GAK63545.1 - 4.6e-07 28.9 17.2 4.3 7.9 0.0 9.5 8 0 0 8 8 8 2 Leucine rich repeat LRR_9 PF14580.1 GAK63545.1 - 0.00048 19.7 2.6 0.92 9.0 0.0 3.5 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 GAK63545.1 - 0.0066 16.3 13.0 2.3 8.5 0.3 6.7 6 2 1 7 7 7 2 Leucine Rich repeat MAP65_ASE1 PF03999.7 GAK63546.1 - 2.8e-54 184.8 0.1 7.7e-49 166.8 0.0 2.1 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF1192 PF06698.6 GAK63546.1 - 0.4 10.5 4.6 5.4 6.9 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Baculo_PEP_C PF04513.7 GAK63546.1 - 0.47 10.2 2.4 0.75 9.6 0.1 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BCDHK_Adom3 PF10436.4 GAK63547.1 - 1.2e-45 154.9 0.1 1.7e-45 154.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAK63547.1 - 2.5e-12 46.4 0.0 1.2e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGP_phosphatase PF09419.5 GAK63548.1 - 7.8e-50 168.5 0.0 2e-45 154.1 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase DUF2373 PF10180.4 GAK63549.1 - 1.8e-14 53.0 0.1 6.6e-09 35.1 0.2 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) CDC45 PF02724.9 GAK63549.1 - 0.15 10.0 12.9 0.28 9.1 8.9 1.5 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 GAK63549.1 - 0.21 9.8 1.7 0.2 9.9 1.2 1.2 1 0 0 1 1 1 0 Membrane transport protein TFIIF_alpha PF05793.7 GAK63549.1 - 0.34 9.2 37.0 0.16 10.2 11.5 2.3 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOBP PF15279.1 GAK63549.1 - 4.4 7.6 19.6 3.1 8.0 12.9 1.4 1 1 0 1 1 1 0 Sine oculis-binding protein Lum_binding PF00677.12 GAK63553.1 - 1.2e-30 105.1 0.0 7.3e-20 70.6 0.0 3.6 3 1 0 3 3 3 3 Lumazine binding domain Homoserine_dh PF00742.14 GAK63554.1 - 1.5e-45 155.1 0.0 2.2e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 GAK63554.1 - 7.8e-14 52.0 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 GAK63554.1 - 0.13 12.5 1.0 1.4 9.2 0.7 2.2 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain BUD22 PF09073.5 GAK63555.1 - 7.3e-86 288.9 32.2 7.3e-86 288.9 22.3 2.1 2 0 0 2 2 2 1 BUD22 GMC_oxred_N PF00732.14 GAK63556.1 - 5e-57 193.2 0.0 7.6e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK63556.1 - 1.2e-36 126.1 0.4 2.3e-36 125.2 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Peptidase_M20 PF01546.23 GAK63556.1 - 7e-25 87.6 0.1 1.6e-24 86.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DAO PF01266.19 GAK63556.1 - 3.6e-06 26.1 1.4 4.6e-06 25.7 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Peptidase_M28 PF04389.12 GAK63556.1 - 7.9e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 GAK63556.1 - 0.0002 21.0 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Lycopene_cycl PF05834.7 GAK63556.1 - 0.0013 17.7 0.0 0.003 16.5 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAK63556.1 - 0.0094 15.9 1.8 0.033 14.2 1.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAK63556.1 - 0.017 15.2 0.2 0.75 9.8 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK63556.1 - 0.024 13.7 0.1 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 GAK63556.1 - 0.53 9.0 5.6 1.1 8.0 3.9 1.5 1 0 0 1 1 1 0 FAD binding domain DLH PF01738.13 GAK63557.1 - 7.1e-20 71.2 0.4 8.2e-20 71.0 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAK63557.1 - 0.00021 21.0 0.2 0.00039 20.1 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Herpes_gE PF02480.11 GAK63558.1 - 0.094 10.9 0.1 0.094 10.9 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pyr_redox_3 PF13738.1 GAK63559.1 - 1.9e-30 106.4 0.0 7.2e-30 104.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAK63559.1 - 1.4e-17 63.0 0.0 2.1e-15 55.9 0.1 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAK63559.1 - 2.3e-10 40.3 0.0 1.2e-08 34.7 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAK63559.1 - 6.5e-08 31.8 0.1 7e-07 28.4 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 GAK63559.1 - 3.5e-05 24.1 0.3 0.0087 16.4 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK63559.1 - 0.00024 20.2 0.0 0.00058 19.0 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAK63559.1 - 0.00057 19.8 0.1 0.017 14.9 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK63559.1 - 0.0059 15.5 0.1 1.4 7.7 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 GAK63559.1 - 0.015 14.2 0.5 0.12 11.2 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK63559.1 - 0.017 14.9 0.4 8.2 6.1 0.0 3.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAK63559.1 - 0.04 12.7 0.1 0.15 10.8 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 GAK63559.1 - 0.084 12.9 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amidohydro_4 PF13147.1 GAK63560.1 - 4.5e-14 53.1 1.3 1e-13 51.9 0.9 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAK63560.1 - 9.5e-12 45.2 0.0 8e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 GAK63560.1 - 1.1e-05 25.1 0.0 2.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAK63560.1 - 3.1e-05 23.3 0.0 9.7e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family DUF3605 PF12239.3 GAK63561.1 - 8e-29 100.5 0.0 3.6e-20 72.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) Med25_VWA PF11265.3 GAK63561.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A BcrAD_BadFG PF01869.15 GAK63562.1 - 5.5e-10 38.9 0.0 9.7e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Glucosamine_iso PF01182.15 GAK63563.1 - 4.1e-25 88.6 0.0 5.9e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Zn_clus PF00172.13 GAK63564.1 - 1.3e-06 28.1 9.0 1.3e-06 28.1 6.2 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3497 PF12003.3 GAK63564.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3497) PGM_PMM_I PF02878.11 GAK63565.1 - 3.5e-35 120.5 0.0 5.5e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAK63565.1 - 7.1e-17 61.6 0.0 2.1e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 GAK63565.1 - 3.6e-11 43.1 0.0 7.6e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 GAK63565.1 - 1.1e-08 34.9 0.0 3.3e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Lipase_3 PF01764.20 GAK63566.1 - 6.5e-12 45.2 1.2 1.1e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF1479 PF07350.7 GAK63567.1 - 4e-144 480.1 0.0 4.8e-144 479.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 GAK63567.1 - 0.023 14.7 0.4 8.1 6.4 0.1 2.7 2 1 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 GAK63568.1 - 2.1e-55 188.1 0.0 2.9e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APS_kinase PF01583.15 GAK63572.1 - 1.5e-69 232.6 0.0 1.8e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 GAK63572.1 - 9.8e-07 28.7 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK63572.1 - 1.1e-05 26.2 0.0 2.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAK63572.1 - 1.1e-05 25.7 0.1 2.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAK63572.1 - 8.7e-05 21.8 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 GAK63572.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 GAK63572.1 - 0.0033 16.5 0.0 0.013 14.5 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 GAK63572.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 GAK63572.1 - 0.061 13.6 0.3 0.069 13.4 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAK63572.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 GAK63572.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 GAK63572.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 GAK63572.1 - 0.15 11.6 0.1 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MaoC_dehydrat_N PF13452.1 GAK63573.1 - 8.7e-09 35.2 0.1 6.3e-06 26.0 0.0 3.0 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.14 GAK63573.1 - 0.00061 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain SelR PF01641.13 GAK63574.1 - 3.1e-50 169.0 0.2 4e-50 168.6 0.2 1.1 1 0 0 1 1 1 1 SelR domain HECT_2 PF09814.4 GAK63574.1 - 0.075 11.7 0.0 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding WD40 PF00400.27 GAK63575.1 - 3.9e-17 61.3 12.4 2.4e-08 33.5 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Phage_holin PF04688.8 GAK63575.1 - 0.06 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage lysis protein, holin WD40 PF00400.27 GAK63576.1 - 7.6e-07 28.7 7.6 0.076 12.9 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Sigma70_ner PF04546.8 GAK63576.1 - 2.3 7.7 5.7 6.2 6.3 0.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region MBOAT_2 PF13813.1 GAK63577.1 - 4.1e-09 36.3 0.9 3.7e-07 30.1 0.6 2.6 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DEAD PF00270.24 GAK63578.1 - 6.1e-45 152.7 0.0 1.4e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK63578.1 - 1.1e-27 95.7 0.0 4.1e-26 90.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK63578.1 - 0.0009 19.1 0.0 0.0009 19.1 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAK63578.1 - 0.0019 17.3 0.0 0.0019 17.3 0.0 3.4 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit TFIIF_alpha PF05793.7 GAK63578.1 - 1 7.6 23.0 1.5 7.1 15.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ycf1 PF05758.7 GAK63578.1 - 1.5 6.4 5.3 1.8 6.1 3.7 1.1 1 0 0 1 1 1 0 Ycf1 DUF2413 PF10310.4 GAK63578.1 - 3.2 6.4 17.3 4.6 5.9 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF966 PF06136.8 GAK63578.1 - 7.7 5.8 13.1 11 5.3 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) adh_short PF00106.20 GAK63579.1 - 1.7e-12 47.6 0.0 2.1e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK63579.1 - 3.9e-06 26.7 0.2 4.5e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK63579.1 - 0.00022 20.9 0.0 0.0013 18.4 0.0 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAK63579.1 - 0.0013 18.7 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding EF-hand_5 PF13202.1 GAK63580.1 - 0.14 11.5 0.5 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 EF hand FAP PF07174.6 GAK63580.1 - 8.1 5.6 22.7 17 4.6 15.7 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ras PF00071.17 GAK63581.1 - 1.1e-52 177.7 0.0 1.3e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK63581.1 - 1.3e-18 67.6 0.0 1.8e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK63581.1 - 2.9e-11 42.9 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAK63581.1 - 2.2e-06 27.2 0.0 3.4e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAK63581.1 - 2.9e-05 23.3 0.0 3.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAK63581.1 - 0.00087 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAK63581.1 - 0.0034 17.5 0.0 0.0053 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAK63581.1 - 0.005 16.8 0.1 0.0079 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 GAK63581.1 - 0.0098 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit KaiC PF06745.8 GAK63581.1 - 0.015 14.4 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 GAK63581.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 GAK63581.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 GAK63581.1 - 0.03 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 GAK63581.1 - 0.095 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.12 GAK63581.1 - 0.099 12.1 0.0 2.1 7.8 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RWD PF05773.17 GAK63582.1 - 7.5e-20 70.9 0.2 1.9e-19 69.5 0.1 1.7 1 0 0 1 1 1 1 RWD domain HypD PF01924.11 GAK63582.1 - 0.11 11.2 0.3 0.15 10.7 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family HlyIII PF03006.15 GAK63583.1 - 6e-57 192.5 16.5 6e-57 192.5 11.5 2.3 2 1 0 2 2 2 1 Haemolysin-III related EBP PF05241.7 GAK63583.1 - 3.7e-07 29.3 6.9 3.7e-07 29.3 4.8 2.5 4 0 0 4 4 4 1 Emopamil binding protein GWT1 PF06423.7 GAK63583.1 - 0.23 11.5 4.0 0.66 10.0 0.1 2.7 2 1 0 2 2 2 0 GWT1 TMPIT PF07851.8 GAK63585.1 - 0.069 12.2 3.1 0.11 11.5 2.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 GAK63585.1 - 0.45 10.0 5.6 1.1 8.8 3.9 1.6 1 0 0 1 1 1 0 IncA protein COMP PF11598.3 GAK63585.1 - 0.73 9.9 5.1 4.8 7.3 3.1 2.7 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein Atg14 PF10186.4 GAK63585.1 - 6.2 5.6 12.6 1.3 7.9 6.2 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Abhydrolase_5 PF12695.2 GAK63588.1 - 1.5e-07 31.2 0.0 9.2e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK63588.1 - 4.8e-06 26.6 0.5 9.4e-06 25.6 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cyt-b5 PF00173.23 GAK63589.1 - 5.2e-22 77.4 0.1 5.7e-22 77.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 GAK63589.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.5 1 1 1 2 2 2 0 V-ATPase subunit H Init_tRNA_PT PF04179.7 GAK63590.1 - 2e-123 412.6 0.0 2.3e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase HORMA PF02301.13 GAK63591.1 - 1.6e-11 44.0 0.0 3.7e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 HORMA domain ABC_tran PF00005.22 GAK63592.1 - 3.5e-50 169.8 0.0 8.3e-30 103.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAK63592.1 - 4.3e-24 85.3 26.0 1.1e-15 57.8 2.5 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_25 PF13481.1 GAK63592.1 - 5.6e-08 32.4 0.1 0.00025 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 GAK63592.1 - 2.2e-07 31.1 0.0 0.056 13.3 0.0 3.4 2 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 GAK63592.1 - 7.5e-06 26.0 4.4 0.0059 16.6 0.2 3.7 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.14 GAK63592.1 - 1.4e-05 24.4 6.2 0.13 11.4 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAK63592.1 - 1.5e-05 24.4 0.4 0.018 14.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 GAK63592.1 - 6.7e-05 23.0 1.0 0.79 9.8 0.3 3.3 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAK63592.1 - 0.0001 21.5 0.4 0.047 12.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 GAK63592.1 - 0.00069 20.0 0.0 0.64 10.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 GAK63592.1 - 0.0029 17.3 2.3 0.26 11.0 0.1 4.0 3 0 0 3 3 3 1 Part of AAA domain cobW PF02492.14 GAK63592.1 - 0.0034 16.8 1.8 1.4 8.3 0.6 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 GAK63592.1 - 0.0057 16.3 1.1 0.38 10.4 0.2 3.0 3 0 0 3 3 3 1 NACHT domain MobB PF03205.9 GAK63592.1 - 0.011 15.4 0.7 0.69 9.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 GAK63592.1 - 0.021 14.7 0.0 6.2 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 GAK63592.1 - 0.03 14.6 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 GAK63592.1 - 0.037 13.4 0.1 1 8.7 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 GAK63592.1 - 0.039 13.4 0.6 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 GAK63592.1 - 0.044 14.0 0.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 GAK63592.1 - 0.053 13.3 0.6 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_17 PF13207.1 GAK63592.1 - 0.068 13.9 0.0 7.2 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 GAK63592.1 - 0.092 12.2 0.4 17 4.8 0.4 3.1 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.7 GAK63592.1 - 0.095 11.9 0.8 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein UPF0079 PF02367.12 GAK63592.1 - 0.16 11.6 0.7 0.36 10.4 0.2 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 MaoC_dehydratas PF01575.14 GAK63594.1 - 7.6e-27 93.1 0.0 2.9e-26 91.2 0.0 2.0 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAK63594.1 - 1.3e-11 44.4 0.0 1e-09 38.2 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase BAR PF03114.13 GAK63595.1 - 6.2e-43 146.9 6.3 8.7e-43 146.4 4.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 GAK63595.1 - 5.5e-15 54.4 0.1 1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAK63595.1 - 1.1e-14 53.6 0.1 2.5e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAK63595.1 - 3.9e-12 45.4 0.0 7.1e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.6 GAK63595.1 - 0.00016 21.0 1.2 0.00024 20.5 0.8 1.2 1 0 0 1 1 1 1 FAM92 protein Vac_Fusion PF02346.11 GAK63595.1 - 0.035 13.5 1.0 12 5.3 0.0 3.7 4 0 0 4 4 4 0 Chordopoxvirus fusion protein Prefoldin PF02996.12 GAK63595.1 - 0.039 13.6 1.5 0.11 12.2 0.1 2.3 2 1 0 2 2 2 0 Prefoldin subunit T4SS PF07996.6 GAK63595.1 - 0.085 12.7 2.5 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion system proteins Glyco_hydro_43 PF04616.9 GAK63597.1 - 7.4e-18 64.6 0.2 1.1e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1295 PF06966.7 GAK63598.1 - 4.6e-52 176.6 0.4 6.2e-52 176.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 GAK63598.1 - 0.00011 22.2 0.1 0.00055 20.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 GAK63598.1 - 0.0015 18.2 1.9 0.0028 17.4 0.0 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 GAK63598.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Methyltransf_16 PF10294.4 GAK63599.1 - 3.1e-14 52.7 0.0 7.4e-12 45.0 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAK63599.1 - 0.00069 20.1 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Metallopep PF12044.3 GAK63600.1 - 5.6e-95 318.2 0.0 5e-73 245.9 0.0 2.1 2 0 0 2 2 2 2 Putative peptidase family Jacalin PF01419.12 GAK63600.1 - 0.032 14.0 0.0 0.13 12.1 0.0 1.8 1 1 1 2 2 2 0 Jacalin-like lectin domain Peptidase_M66 PF10462.4 GAK63600.1 - 0.072 11.9 0.2 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Aldo_ket_red PF00248.16 GAK63601.1 - 3.2e-56 190.2 0.0 3.8e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Toxin_51 PF15531.1 GAK63601.1 - 0.021 14.6 0.3 1.4 8.7 0.0 2.7 2 1 1 3 3 3 0 Putative toxin 51 YflT PF11181.3 GAK63601.1 - 0.021 14.9 0.1 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF2256 PF10013.4 GAK63602.1 - 1.6e-11 43.7 3.7 2.7e-11 43.0 2.6 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.2 GAK63602.1 - 0.012 14.9 0.7 0.027 13.7 0.5 1.5 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 GAK63602.1 - 0.036 13.9 0.7 0.072 12.9 0.5 1.4 1 0 0 1 1 1 0 MYND finger Aldose_epim PF01263.15 GAK63603.1 - 4.9e-29 101.3 0.0 8.6e-29 100.5 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase Xan_ur_permease PF00860.15 GAK63605.1 - 1.3e-26 93.0 25.9 1.8e-25 89.2 17.9 2.2 1 1 0 1 1 1 1 Permease family ABC_tran PF00005.22 GAK63607.1 - 2.3e-50 170.4 0.8 4.2e-28 98.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAK63607.1 - 4e-31 108.4 18.9 5.1e-20 72.0 4.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAK63607.1 - 1.4e-09 37.4 5.9 0.0018 17.5 1.5 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAK63607.1 - 3.4e-09 37.0 0.1 0.28 11.1 0.0 4.6 4 1 0 4 4 4 3 AAA domain AAA_29 PF13555.1 GAK63607.1 - 4.7e-07 29.2 1.1 0.044 13.3 0.0 3.2 4 0 0 4 4 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAK63607.1 - 8.3e-06 25.3 0.4 0.076 12.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 GAK63607.1 - 1.3e-05 24.8 1.4 0.44 9.9 0.0 3.9 4 0 0 4 4 4 2 AAA-like domain DUF258 PF03193.11 GAK63607.1 - 1.3e-05 24.4 0.0 0.095 11.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAK63607.1 - 3.9e-05 23.8 0.3 0.17 12.0 0.2 3.4 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 GAK63607.1 - 4.5e-05 23.0 0.0 0.28 10.6 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family Miro PF08477.8 GAK63607.1 - 0.0002 21.8 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 GAK63607.1 - 0.00027 20.8 0.0 0.97 9.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 GAK63607.1 - 0.0028 18.0 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAK63607.1 - 0.014 14.9 1.5 0.12 11.9 0.4 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAK63607.1 - 0.017 15.1 4.8 0.057 13.4 0.3 3.0 2 1 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 GAK63607.1 - 0.035 13.0 0.0 4.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 GAK63607.1 - 0.036 13.5 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 GAK63607.1 - 0.045 13.6 0.0 12 5.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 GAK63607.1 - 0.056 13.1 0.1 2.2 7.9 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAK63607.1 - 0.093 12.5 0.5 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.1 GAK63607.1 - 0.098 12.5 1.8 1.9 8.4 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 GAK63607.1 - 0.098 11.4 1.1 5.5 5.7 0.0 3.2 4 0 0 4 4 4 0 NB-ARC domain Septin PF00735.13 GAK63607.1 - 0.13 11.3 0.0 9.3 5.1 0.0 2.6 3 0 0 3 3 3 0 Septin NTPase_1 PF03266.10 GAK63607.1 - 0.15 11.7 0.6 23 4.6 0.0 3.1 3 0 0 3 3 3 0 NTPase cobW PF02492.14 GAK63607.1 - 0.15 11.4 0.9 3.4 7.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 GAK63607.1 - 0.21 11.3 0.6 0.43 10.3 0.1 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF87 Pox_A32 PF04665.7 GAK63607.1 - 0.35 10.1 2.0 0.33 10.2 0.1 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_ATPase PF09818.4 GAK63607.1 - 1.6 7.2 7.5 0.28 9.6 0.0 2.8 4 0 0 4 4 4 0 Predicted ATPase of the ABC class MARVEL PF01284.18 GAK63608.1 - 7.3e-08 32.3 6.4 1.1e-07 31.7 4.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain DctQ PF04290.7 GAK63608.1 - 1.8 8.3 9.9 0.52 10.0 1.3 2.4 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Cmc1 PF08583.5 GAK63609.1 - 3.9e-13 48.9 0.7 4.6e-13 48.7 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 GAK63609.1 - 6.1e-05 22.3 0.7 8.5e-05 21.8 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PCI_Csn8 PF10075.4 GAK63609.1 - 0.053 13.2 0.0 0.078 12.7 0.0 1.5 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 Pet191_N PF10203.4 GAK63609.1 - 0.11 12.5 0.3 2.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF2237 PF09996.4 GAK63610.1 - 6.6e-33 112.6 0.2 1.6e-32 111.4 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) LRR_8 PF13855.1 GAK63611.1 - 2e-19 69.0 44.6 2e-09 37.0 4.3 4.4 3 1 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 GAK63611.1 - 4.5e-15 54.8 23.4 1.3e-07 31.0 1.4 6.0 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAK63611.1 - 2.5e-06 26.7 26.3 0.8 9.9 0.2 8.0 8 1 1 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.1 GAK63611.1 - 0.00027 20.5 0.3 0.025 14.1 0.2 3.0 3 0 0 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.1 GAK63611.1 - 0.0022 17.8 15.4 0.31 11.2 0.1 6.3 5 1 1 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 GAK63611.1 - 0.0056 16.6 29.2 4.6 7.8 0.5 8.4 10 0 0 10 10 10 3 Leucine rich repeat AA_permease_2 PF13520.1 GAK63612.1 - 1.4e-60 205.0 36.9 1.8e-60 204.7 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAK63612.1 - 2.5e-28 98.6 34.0 3.2e-28 98.3 23.5 1.1 1 0 0 1 1 1 1 Amino acid permease FDF PF09532.5 GAK63613.1 - 2.8e-05 24.5 0.1 0.00015 22.2 0.0 2.2 2 0 0 2 2 2 1 FDF domain DUF4140 PF13600.1 GAK63613.1 - 0.56 10.6 7.1 0.32 11.4 0.1 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) NUDIX PF00293.23 GAK63614.1 - 2.7e-13 49.7 0.0 7.6e-13 48.2 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DnaJ PF00226.26 GAK63615.1 - 1e-24 86.0 1.4 1.8e-24 85.2 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAK63615.1 - 2.8e-20 72.0 0.1 8.5e-19 67.2 0.0 3.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAK63615.1 - 1.5e-13 50.5 19.1 2.4e-13 49.8 13.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 GAK63615.1 - 0.0068 16.7 10.2 0.014 15.6 6.7 1.8 1 1 1 2 2 2 2 Cytochrome c3 Stc1 PF12898.2 GAK63615.1 - 0.14 12.2 12.5 0.81 9.7 2.9 2.3 1 1 1 2 2 2 0 Stc1 domain Cytochrome_C7 PF14522.1 GAK63615.1 - 4 7.1 13.7 23 4.7 9.5 2.1 1 1 0 1 1 1 0 Cytochrome c7 Lar_restr_allev PF14354.1 GAK63615.1 - 5.1 7.4 7.5 1.8 8.9 2.0 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar Cytochrom_CIII PF02085.11 GAK63615.1 - 5.1 7.2 9.8 3.2 7.9 2.8 1.6 1 1 1 2 2 2 0 Class III cytochrome C family HypA PF01155.14 GAK63615.1 - 5.8 6.6 13.1 0.85 9.3 2.6 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DcpS PF05652.7 GAK63616.1 - 8.4e-30 103.4 0.0 1.4e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 GAK63616.1 - 6.7e-26 90.8 0.3 1.3e-25 89.8 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DHBP_synthase PF00926.14 GAK63617.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase FAP PF07174.6 GAK63617.1 - 0.048 12.9 7.8 0.086 12.1 5.4 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TFIIA PF03153.8 GAK63617.1 - 0.36 10.6 12.0 0.47 10.3 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2638 PF10937.3 GAK63617.1 - 2.8 8.9 8.4 3.1 8.8 4.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2638) Glyco_hydro_85 PF03644.8 GAK63618.1 - 1.1e-93 313.8 0.0 1.4e-93 313.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 IU_nuc_hydro PF01156.14 GAK63619.1 - 2.1e-59 201.3 0.0 3.2e-59 200.6 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Mito_carr PF00153.22 GAK63620.1 - 2.8e-50 167.9 4.2 2.2e-17 62.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 GAK63620.1 - 0.034 14.0 0.0 4.1 7.3 0.0 2.9 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Med3 PF11593.3 GAK63620.1 - 1.9 7.6 3.7 3 7.0 2.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Transthyretin PF00576.16 GAK63621.1 - 1e-32 112.3 0.0 1.2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 GAK63621.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain DUF4215 PF13948.1 GAK63624.1 - 0.022 14.9 7.1 2.9 8.1 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4215) DUF3116 PF11313.3 GAK63624.1 - 0.24 11.0 0.3 22 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3116) CBM_14 PF01607.19 GAK63624.1 - 0.59 10.1 10.8 46 4.0 0.3 4.1 4 0 0 4 4 4 0 Chitin binding Peritrophin-A domain PQ-loop PF04193.9 GAK63625.1 - 2.5e-23 81.4 1.3 1.5e-11 43.6 0.5 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.13 GAK63625.1 - 0.2 12.1 4.5 0.37 11.2 3.1 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor Polysacc_synt_C PF14667.1 GAK63625.1 - 2.7 7.7 11.4 1.9 8.3 3.8 2.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain SNase PF00565.12 GAK63626.1 - 3.1e-20 72.4 1.2 1.8e-08 34.6 0.6 3.2 1 1 1 2 2 2 2 Staphylococcal nuclease homologue GFO_IDH_MocA PF01408.17 GAK63627.1 - 6.3e-15 55.7 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAK63627.1 - 9.1e-13 48.0 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_92 PF07971.7 GAK63628.1 - 5.2e-158 526.8 0.0 6.8e-158 526.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Aldose_epim PF01263.15 GAK63629.1 - 6.6e-60 202.7 0.2 8.8e-60 202.3 0.2 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1275 PF06912.6 GAK63629.1 - 2.7e-17 62.6 15.8 4.9e-17 61.8 10.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1275) DUF46 PF01864.12 GAK63629.1 - 0.17 11.7 0.2 0.31 10.8 0.1 1.3 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 CoA_binding_2 PF13380.1 GAK63630.1 - 1.1e-26 93.2 0.1 1.3e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain Herpes_gp2 PF05955.6 GAK63630.1 - 0.026 13.8 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 CoA_binding PF02629.14 GAK63630.1 - 0.079 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain FAA_hydrolase PF01557.13 GAK63631.1 - 7.9e-56 188.9 0.0 1e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2470 PF10615.4 GAK63632.1 - 6.1e-25 87.2 0.0 1.1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 GAK63632.1 - 0.00026 20.8 1.0 0.00041 20.2 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) GSHPx PF00255.14 GAK63633.1 - 5.5e-40 135.0 1.3 7.3e-40 134.6 0.9 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 GAK63633.1 - 9.3e-07 28.5 0.3 6.1e-06 25.9 0.2 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAK63633.1 - 1.2e-06 28.1 0.1 2.2e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 GAK63633.1 - 0.0049 16.9 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) PA PF02225.17 GAK63633.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 PA domain Thioredoxin_2 PF13098.1 GAK63633.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain S-methyl_trans PF02574.11 GAK63636.1 - 8.6e-24 84.3 3.3 3.1e-20 72.7 0.0 4.0 2 2 0 2 2 2 2 Homocysteine S-methyltransferase Polysacc_deac_1 PF01522.16 GAK63638.1 - 9.2e-22 76.9 0.0 1.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Erg28 PF03694.8 GAK63639.1 - 8.5e-37 125.5 1.4 1.1e-36 125.2 0.9 1.1 1 0 0 1 1 1 1 Erg28 like protein DNA_ligase_OB_2 PF14743.1 GAK63640.1 - 6.2e-24 83.4 0.0 2.9e-23 81.3 0.0 2.1 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 GAK63640.1 - 7.4e-13 48.3 0.0 1.1e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain Abhydrolase_3 PF07859.8 GAK63641.1 - 1.7e-38 132.3 0.4 2.9e-31 108.6 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 GAK63641.1 - 2.3e-09 36.3 0.0 1.4e-08 33.8 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAK63641.1 - 9.9e-05 22.1 0.0 0.00037 20.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAK63641.1 - 0.034 12.6 0.0 0.072 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.23 GAK63641.1 - 0.04 12.6 0.2 1.4 7.5 0.0 2.6 3 0 0 3 3 3 0 Carboxylesterase family Aldo_ket_red PF00248.16 GAK63643.1 - 1e-64 218.1 0.0 1.2e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family A_deaminase PF00962.17 GAK63644.1 - 5.3e-49 166.9 0.0 7.7e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 GAK63644.1 - 0.044 13.7 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Sulfotransfer_3 PF13469.1 GAK63645.1 - 0.038 14.9 0.0 0.077 13.9 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family Mg_trans_NIPA PF05653.9 GAK63647.1 - 1.6e-91 306.3 23.7 2.3e-91 305.9 16.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 GAK63647.1 - 8.7e-07 29.0 7.0 8.7e-07 29.0 4.8 3.4 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 GAK63647.1 - 3.4e-06 27.2 6.0 3.4e-06 27.2 4.1 3.3 2 1 0 3 3 3 1 Multidrug resistance efflux transporter WSN PF02206.13 GAK63647.1 - 0.0018 17.9 0.3 0.0037 16.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function Neurensin PF14927.1 GAK63647.1 - 7 6.0 7.5 24 4.3 0.4 2.8 2 0 0 2 2 2 0 Neurensin Mito_carr PF00153.22 GAK63648.1 - 1.3e-54 181.8 4.4 2.9e-19 68.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein START PF01852.14 GAK63649.1 - 5.1e-09 35.7 0.3 8.7e-09 34.9 0.2 1.3 1 0 0 1 1 1 1 START domain MoaE PF02391.12 GAK63650.1 - 1.9e-27 95.3 0.1 7.2e-27 93.5 0.1 1.8 1 1 0 1 1 1 1 MoaE protein Ribonuclease PF00545.15 GAK63651.1 - 2.6e-18 65.8 1.9 3.2e-18 65.5 1.3 1.1 1 0 0 1 1 1 1 ribonuclease Ustilago_mating PF05722.7 GAK63652.1 - 0.13 11.5 0.1 1.4 8.1 0.1 1.9 2 0 0 2 2 2 0 Ustilago B locus mating-type protein Frag1 PF10277.4 GAK63653.1 - 2.9e-36 124.9 20.4 3.5e-36 124.7 14.1 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 2TM PF13239.1 GAK63653.1 - 1.3 9.1 7.0 0.64 10.1 1.7 2.5 2 0 0 2 2 2 0 2TM domain Aminotran_1_2 PF00155.16 GAK63654.1 - 1.1e-16 60.7 0.0 1.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 GAK63654.1 - 1.9e-07 30.0 0.0 5.8e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase NCA2 PF08637.5 GAK63655.1 - 2.8e-93 311.9 0.0 2.1e-92 309.0 0.0 2.1 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Thioredoxin PF00085.15 GAK63656.1 - 1.1e-61 204.9 0.1 4.8e-31 106.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 GAK63656.1 - 7.1e-25 87.4 2.7 9.7e-25 87.0 0.4 2.4 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 GAK63656.1 - 6.5e-15 55.3 2.3 4.9e-08 33.1 0.0 3.5 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAK63656.1 - 1.8e-11 44.0 0.3 0.00024 21.1 0.0 3.9 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 GAK63656.1 - 1.2e-10 41.2 0.7 1.1e-06 28.5 0.1 2.8 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 GAK63656.1 - 9.5e-09 35.0 0.1 0.002 17.8 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_6 PF13848.1 GAK63656.1 - 2.1e-05 24.4 0.2 0.0004 20.2 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 GAK63656.1 - 2.3e-05 23.9 0.0 0.31 10.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 GAK63656.1 - 4.1e-05 23.1 0.1 0.22 11.0 0.0 2.5 2 0 0 2 2 2 2 Redoxin HyaE PF07449.6 GAK63656.1 - 0.00011 22.0 0.0 0.0048 16.7 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 GAK63656.1 - 0.00045 19.9 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Glutaredoxin PF00462.19 GAK63656.1 - 0.068 13.1 2.5 7.3 6.6 0.1 3.3 2 2 0 2 2 2 0 Glutaredoxin TetR_C_5 PF08360.6 GAK63656.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Thioredoxin_4 PF13462.1 GAK63656.1 - 0.14 12.2 8.1 0.36 10.8 0.1 3.7 3 2 1 4 4 4 0 Thioredoxin XPG_I_2 PF12813.2 GAK63657.1 - 1.8e-09 37.4 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 GAK63657.1 - 8e-05 22.8 0.0 0.0033 17.6 0.0 2.5 1 1 0 1 1 1 1 XPG N-terminal domain Lactamase_B PF00753.22 GAK63658.1 - 1.5e-18 67.1 0.6 4.5e-18 65.5 0.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAK63658.1 - 9.2e-06 25.3 0.1 1.3e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Evr1_Alr PF04777.8 GAK63659.1 - 3.6e-29 100.5 0.2 6.2e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Glyco_hydro_cc PF11790.3 GAK63660.1 - 7.6e-37 127.0 0.0 1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Macoilin PF09726.4 GAK63660.1 - 1.4e-06 26.9 14.5 1.6e-06 26.7 10.0 1.1 1 0 0 1 1 1 1 Transmembrane protein Polyoma_lg_T_C PF06431.6 GAK63660.1 - 0.13 10.8 0.1 0.13 10.8 0.1 2.1 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus Neur_chan_memb PF02932.11 GAK63660.1 - 0.3 10.9 2.4 0.49 10.2 1.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Menin PF05053.8 GAK63660.1 - 0.38 8.8 8.4 0.55 8.3 5.8 1.2 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 GAK63660.1 - 0.8 7.3 8.2 1 6.9 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Aldose_epim PF01263.15 GAK63661.1 - 1.2e-11 44.2 0.0 2.3e-09 36.7 0.0 2.8 1 1 0 1 1 1 1 Aldose 1-epimerase CIA30 PF08547.7 GAK63662.1 - 9e-22 77.6 0.0 3.3e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) His_Phos_2 PF00328.17 GAK63663.1 - 7.9e-15 55.0 0.0 1.7e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Acatn PF13000.2 GAK63664.1 - 1.8e-139 465.7 31.7 1.9e-68 231.3 10.5 4.7 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Peptidase_M48 PF01435.13 GAK63665.1 - 3.1e-32 111.9 0.0 5.6e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 HTH_1 PF00126.22 GAK63665.1 - 1.1 9.0 3.8 14 5.4 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family adh_short PF00106.20 GAK63666.1 - 3e-16 59.7 0.6 1.5e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAK63666.1 - 8.9e-06 25.4 0.1 1.8e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 KR domain FliG_N PF14842.1 GAK63666.1 - 0.057 13.5 0.1 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 FliG N-terminal domain SurA_N PF09312.6 GAK63666.1 - 0.1 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 SurA N-terminal domain FtsJ PF01728.14 GAK63667.1 - 3.7e-60 203.0 0.0 4.6e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase rRNA_processing PF08524.6 GAK63668.1 - 1e-09 38.3 9.1 3.3e-06 26.9 0.1 2.3 2 0 0 2 2 2 2 rRNA processing Methyltransf_PK PF05891.7 GAK63669.1 - 1.1e-60 204.6 0.0 4.6e-34 117.6 0.0 3.0 2 1 1 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 GAK63669.1 - 3.4e-09 36.6 0.0 5.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK63669.1 - 6.8e-06 26.4 0.0 0.0052 17.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 GAK63669.1 - 0.00017 21.8 0.0 0.0043 17.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK63669.1 - 0.00026 21.5 0.0 0.00053 20.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK63669.1 - 0.00088 19.7 0.0 0.02 15.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAK63669.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF295 PF03478.13 GAK63669.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF295) DUF1399 PF07173.7 GAK63670.1 - 2e-17 63.7 0.4 2.8e-14 53.5 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF1399) Glyco_transf_15 PF01793.11 GAK63672.1 - 2e-126 421.4 3.8 2.5e-126 421.1 2.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase adh_short PF00106.20 GAK63673.1 - 1.9e-31 109.2 2.6 2.6e-31 108.7 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK63673.1 - 1.1e-25 90.8 1.4 3.2e-25 89.3 1.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK63673.1 - 5e-14 52.3 0.8 7.5e-14 51.7 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAK63673.1 - 0.0036 16.9 0.9 0.0057 16.3 0.6 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 GAK63673.1 - 0.026 13.9 0.2 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.9 GAK63673.1 - 0.11 11.8 0.3 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.21 GAK63674.1 - 0.088 12.3 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Transp_Tc5_C PF04236.10 GAK63674.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain AAA_17 PF13207.1 GAK63675.1 - 3.8e-05 24.4 0.0 7.7e-05 23.5 0.0 1.8 2 1 0 2 2 1 1 AAA domain Torsin PF06309.6 GAK63675.1 - 5.3e-05 23.0 0.0 0.00029 20.7 0.0 2.0 2 0 0 2 2 2 1 Torsin MobB PF03205.9 GAK63675.1 - 9.3e-05 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 GAK63675.1 - 0.00023 20.3 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.17 GAK63675.1 - 0.00045 19.7 0.1 0.0013 18.2 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 GAK63675.1 - 0.00056 19.9 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 GAK63675.1 - 0.00061 19.6 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAK63675.1 - 0.0018 18.0 0.1 0.027 14.2 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAK63675.1 - 0.0031 17.1 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain LpxK PF02606.9 GAK63675.1 - 0.0031 16.5 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase APS_kinase PF01583.15 GAK63675.1 - 0.0043 16.7 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 GAK63675.1 - 0.0053 16.0 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 GAK63675.1 - 0.0053 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 NTPase ArgK PF03308.11 GAK63675.1 - 0.0066 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein ATP_bind_1 PF03029.12 GAK63675.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 GAK63675.1 - 0.011 15.5 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAK63675.1 - 0.014 15.7 0.0 0.031 14.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 GAK63675.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 GAK63675.1 - 0.021 14.3 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 GAK63675.1 - 0.021 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 GAK63675.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 GAK63675.1 - 0.026 14.1 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 6PF2K PF01591.13 GAK63675.1 - 0.031 13.3 0.0 0.42 9.6 0.0 2.0 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.12 GAK63675.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase ABC_tran PF00005.22 GAK63675.1 - 0.037 14.3 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.18 GAK63675.1 - 0.041 13.2 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 GAK63675.1 - 0.067 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 GAK63675.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SMC_N PF02463.14 GAK63675.1 - 0.088 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 GAK63675.1 - 0.095 12.4 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 GAK63675.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF938 PF06080.7 GAK63676.1 - 1.9e-32 112.4 0.0 6.3e-32 110.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Nucleo_P87 PF07267.6 GAK63678.1 - 0.38 9.3 0.5 1.3 7.6 0.4 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 His_Phos_2 PF00328.17 GAK63680.1 - 3.7e-24 85.6 0.0 4.8e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SPC12 PF06645.8 GAK63681.1 - 1.3e-24 85.8 0.1 1.4e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Polysacc_synt_3 PF13440.1 GAK63681.1 - 0.034 13.6 0.4 0.035 13.5 0.3 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ETRAMP PF09716.5 GAK63681.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4564 PF15169.1 GAK63681.1 - 0.14 11.9 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Fungal_trans PF04082.13 GAK63682.1 - 4.6e-22 78.1 0.9 1.4e-21 76.5 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK63682.1 - 7.3e-08 32.1 8.7 1.2e-07 31.4 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-L-AF_C PF06964.7 GAK63683.1 - 4.1e-28 98.3 0.0 8e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus EAF PF09816.4 GAK63683.1 - 1.1e-23 83.3 0.0 2.5e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CBM_4_9 PF02018.12 GAK63683.1 - 0.0008 19.4 0.7 0.0034 17.3 0.5 2.1 1 1 0 1 1 1 1 Carbohydrate binding domain NAD_binding_4 PF07993.7 GAK63685.1 - 1.2e-34 119.4 0.0 2.5e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAK63685.1 - 4.8e-31 107.5 0.0 1.1e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAK63685.1 - 1.8e-08 34.1 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAK63685.1 - 1.8e-05 24.4 0.4 4.1e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAK63685.1 - 3.3e-05 23.8 2.8 7.6e-05 22.6 0.6 2.6 2 1 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 GAK63685.1 - 0.00051 18.8 0.0 0.0013 17.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 GAK63685.1 - 0.0053 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site HAD_2 PF13419.1 GAK63686.1 - 2e-10 41.1 1.1 4e-09 36.9 0.7 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAK63686.1 - 3e-05 23.6 0.0 7.6e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAK63686.1 - 0.029 14.7 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-DHHC PF01529.15 GAK63689.1 - 1.4e-55 187.3 0.3 7.2e-55 185.0 0.0 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Hemagglutinin PF00509.13 GAK63689.1 - 0.075 11.1 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin DZR PF12773.2 GAK63689.1 - 5.3 6.9 11.1 0.23 11.2 3.6 1.7 2 0 0 2 2 2 0 Double zinc ribbon LIM PF00412.17 GAK63690.1 - 4.4e-21 74.7 16.4 1e-11 44.7 4.4 2.4 2 0 0 2 2 2 2 LIM domain Cytochrom_c3_2 PF14537.1 GAK63690.1 - 2.3 8.6 10.7 1.6 9.1 2.7 2.5 2 0 0 2 2 2 0 Cytochrome c3 PMSR PF01625.16 GAK63691.1 - 1.3e-55 187.5 2.2 1.7e-55 187.1 1.5 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Exo70 PF03081.10 GAK63692.1 - 6.6e-82 275.2 0.0 3.3e-81 272.9 0.0 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.7 GAK63692.1 - 0.51 10.1 2.9 7.2 6.4 0.2 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SLT PF01464.15 GAK63693.1 - 0.00025 20.5 1.3 0.11 11.9 0.0 3.0 3 0 0 3 3 3 2 Transglycosylase SLT domain DUF2589 PF11655.3 GAK63693.1 - 0.019 15.1 1.1 0.032 14.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) Thiolase_N PF00108.18 GAK63694.1 - 6.4e-73 244.9 0.2 9e-73 244.4 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAK63694.1 - 2.1e-42 143.4 0.1 3.9e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAK63694.1 - 0.011 15.2 2.1 0.013 15.0 0.4 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Nucleos_tra2_C PF07662.8 GAK63695.1 - 1.9e-63 213.7 7.0 1.9e-63 213.7 4.9 2.2 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 GAK63695.1 - 1.5e-07 31.6 6.3 1.5e-07 31.6 4.4 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 GAK63695.1 - 0.88 9.4 21.2 0.1 12.4 8.9 3.3 2 1 1 3 3 3 0 Nucleoside recognition DPM2 PF07297.7 GAK63696.1 - 2.1e-15 56.7 0.1 2.4e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 GAK63696.1 - 5.2e-07 29.3 0.0 5.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 PIG-P DUF1469 PF07332.6 GAK63696.1 - 0.029 14.1 2.0 0.034 13.8 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Peptidase_S24 PF00717.18 GAK63698.1 - 4e-06 26.3 0.1 0.00028 20.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 GAK63698.1 - 0.0039 16.7 0.0 0.093 12.2 0.0 2.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 DUF1517 PF07466.6 GAK63698.1 - 0.63 8.9 2.5 0.96 8.3 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3425 PF11905.3 GAK63699.1 - 1.2e-10 41.4 7.2 1.6e-10 40.9 0.8 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAK63699.1 - 1.1e-08 34.8 8.2 1.1e-08 34.8 5.7 2.2 2 1 0 2 2 2 1 bZIP transcription factor SprA-related PF12118.3 GAK63699.1 - 0.14 11.4 27.7 0.71 9.1 6.0 2.2 2 0 0 2 2 2 0 SprA-related family XAP5 PF04921.9 GAK63699.1 - 5.6 6.4 16.6 9 5.7 0.9 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator VHS PF00790.14 GAK63700.1 - 1.2e-26 93.0 0.0 2.8e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 GAK63700.1 - 1.8e-06 27.8 4.6 6.1e-06 26.1 1.4 2.5 2 0 0 2 2 2 1 GAT domain Asp-B-Hydro_N PF05279.6 GAK63701.1 - 1.7 8.4 22.9 45 3.7 14.7 2.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Carn_acyltransf PF00755.15 GAK63702.1 - 4.3e-167 556.7 0.0 5.4e-167 556.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1505 PF07403.6 GAK63703.1 - 0.041 13.8 1.5 0.43 10.5 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1505) zf-CHY PF05495.7 GAK63706.1 - 3.3e-15 56.0 15.8 4.4e-15 55.5 10.9 1.2 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_2 PF13240.1 GAK63706.1 - 0.0025 17.2 5.7 0.14 11.6 0.1 3.1 2 1 0 2 2 2 2 zinc-ribbon domain zf-FPG_IleRS PF06827.9 GAK63706.1 - 0.0031 17.1 0.9 0.0031 17.1 0.6 2.2 2 1 0 2 2 1 1 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.2 GAK63706.1 - 0.04 13.7 10.2 1.2 9.0 4.4 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cys_rich_KTR PF14205.1 GAK63706.1 - 0.15 11.5 5.2 3.7 7.0 2.4 2.3 1 1 1 2 2 2 0 Cysteine-rich KTR zf-ribbon_3 PF13248.1 GAK63706.1 - 0.18 11.0 8.3 9.4 5.5 5.8 2.6 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 GAK63706.1 - 0.48 10.4 14.2 0.7 9.9 2.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 GAK63706.1 - 0.59 9.9 10.8 2.7 7.8 7.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 GAK63706.1 - 1.1 8.9 8.8 0.062 12.9 0.9 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 GAK63706.1 - 1.1 8.9 9.3 1.4 8.6 3.7 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1 PF03811.8 GAK63706.1 - 4.7 6.7 11.5 1.4 8.4 1.1 3.1 3 0 0 3 3 3 0 InsA N-terminal domain Evr1_Alr PF04777.8 GAK63706.1 - 6 6.8 10.1 1.4e+02 2.4 7.0 2.7 1 1 0 1 1 1 0 Erv1 / Alr family C1_4 PF07975.7 GAK63706.1 - 6 6.9 11.8 2.4 8.2 2.5 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain zf-RING_3 PF14369.1 GAK63706.1 - 8 6.5 12.4 1.2 9.1 2.5 2.9 2 1 1 3 3 3 0 zinc-finger Ofd1_CTDD PF10637.4 GAK63707.1 - 1.7e-98 328.9 0.0 5.9e-93 310.8 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 GAK63707.1 - 4.8e-18 65.5 0.1 1.3e-17 64.1 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SCP2 PF02036.12 GAK63708.1 - 2e-17 63.3 0.0 3.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 GAK63708.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal GPI-anchored PF10342.4 GAK63709.1 - 6.6e-10 39.3 2.0 1.3e-09 38.3 0.0 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.27 GAK63709.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat Abhydrolase_1 PF00561.15 GAK63710.1 - 2.5e-18 66.4 0.1 4.7e-17 62.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK63710.1 - 2.1e-16 60.4 0.2 3.4e-16 59.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK63710.1 - 7.4e-07 29.0 0.0 0.0044 16.7 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 GAK63710.1 - 0.0022 17.2 0.1 0.0086 15.3 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAK63710.1 - 0.0032 16.7 0.0 0.031 13.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 GAK63710.1 - 0.14 11.8 0.0 0.52 9.9 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal EHN PF06441.7 GAK63711.1 - 1.4e-31 108.7 0.2 2.3e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAK63711.1 - 1.6e-08 34.6 1.0 2.5e-08 34.0 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK63711.1 - 1.3e-05 24.9 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PhzC-PhzF PF02567.11 GAK63712.1 - 2.9e-45 154.6 0.0 3.5e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein PhoD PF09423.5 GAK63713.1 - 2.4e-140 468.1 8.6 2.8e-140 467.8 6.0 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAK63713.1 - 0.052 13.3 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Phytase-like PF13449.1 GAK63714.1 - 1.5e-17 63.8 0.0 4.5e-17 62.3 0.0 1.8 2 1 0 2 2 2 1 Esterase-like activity of phytase Mito_carr PF00153.22 GAK63715.1 - 1.6e-29 101.4 20.1 9.1e-12 44.5 0.2 5.1 3 2 0 3 3 3 3 Mitochondrial carrier protein GIY-YIG PF01541.19 GAK63716.1 - 0.00034 20.9 0.0 0.0007 19.9 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Arginase PF00491.16 GAK63717.1 - 5.8e-82 275.1 0.1 8.3e-82 274.5 0.1 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 GAK63717.1 - 0.076 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 UPF0489 domain FGGY_C PF02782.11 GAK63718.1 - 7.1e-46 156.3 0.0 1.2e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAK63718.1 - 1.2e-19 70.6 0.9 1.2e-17 64.0 0.6 3.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 GAK63718.1 - 5.7e-07 29.1 0.9 1.8e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family PTH2 PF01981.11 GAK63719.1 - 5.2e-44 148.6 0.1 6.4e-44 148.3 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ADH_N PF08240.7 GAK63720.1 - 3.7e-23 81.3 8.7 3.7e-23 81.3 6.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK63720.1 - 3e-17 62.3 0.5 2.1e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK63720.1 - 1.3e-05 26.0 0.0 2.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAK63720.1 - 8.3e-05 21.8 0.1 0.00087 18.4 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 GAK63720.1 - 0.0061 15.2 0.0 0.0088 14.7 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NADH_4Fe-4S PF10589.4 GAK63720.1 - 0.058 12.5 0.9 0.14 11.3 0.6 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ApbA PF02558.11 GAK63720.1 - 0.086 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAK63720.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SBF PF01758.11 GAK63721.1 - 6.6e-46 156.0 13.4 6.6e-46 156.0 9.3 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family p450 PF00067.17 GAK63722.1 - 5.8e-55 186.6 0.0 2.5e-35 121.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DRMBL PF07522.9 GAK63723.1 - 1.1e-26 92.9 0.0 2.1e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 GAK63723.1 - 1.8e-07 30.9 0.0 3.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PRP21_like_P PF12230.3 GAK63723.1 - 0.18 11.2 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein PI-PLC-X PF00388.14 GAK63724.1 - 3.4e-47 159.5 0.0 5.1e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAK63724.1 - 1.8e-32 111.7 0.0 2.8e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 GAK63724.1 - 6.1e-05 22.7 0.6 0.0027 17.5 0.1 3.4 3 1 0 3 3 3 1 C2 domain Peptidase_M50B PF13398.1 GAK63725.1 - 0.0084 15.5 3.2 0.011 15.1 2.2 1.1 1 0 0 1 1 1 1 Peptidase M50B-like SET PF00856.23 GAK63726.1 - 1.4e-05 25.4 0.0 0.00044 20.5 0.0 2.8 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.12 GAK63726.1 - 0.47 10.4 6.4 0.37 10.8 1.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 GAK63727.1 - 3.5e-31 108.2 26.0 5.7e-16 58.1 2.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAK63727.1 - 2.2e-18 66.0 51.3 3.8e-12 45.6 19.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.1 GAK63728.1 - 1.7e-25 89.0 0.0 3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK63728.1 - 5e-18 64.8 0.0 1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAK63728.1 - 3.4e-10 39.9 0.0 5.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAK63728.1 - 0.00011 22.0 0.0 0.00033 20.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Abhydrolase_5 PF12695.2 GAK63729.1 - 2.2e-06 27.4 0.1 6.5e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK63729.1 - 2.6e-06 26.7 0.0 5.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAK63729.1 - 0.0024 17.4 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4115 PF13464.1 GAK63729.1 - 0.01 15.4 0.1 0.04 13.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) GMC_oxred_N PF00732.14 GAK63730.1 - 1.6e-74 250.7 0.0 2e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK63730.1 - 4.3e-38 130.8 0.1 7.6e-38 130.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAK63730.1 - 0.0016 17.4 0.4 0.0059 15.5 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK63730.1 - 0.0041 17.1 0.0 0.016 15.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAK63730.1 - 0.0059 15.5 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAK63730.1 - 0.07 11.9 0.1 0.07 11.9 0.1 2.4 3 0 0 3 3 3 0 FAD binding domain UPF0075 PF03702.9 GAK63730.1 - 0.13 11.1 0.0 0.83 8.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0075) Lactamase_B_2 PF12706.2 GAK63731.1 - 2.4e-29 102.2 0.0 7e-29 100.7 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_31 PF13847.1 GAK63731.1 - 1.5e-15 57.1 0.0 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK63731.1 - 1.2e-12 48.4 0.0 4e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK63731.1 - 8.5e-07 29.3 0.0 1.7e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK63731.1 - 2.6e-06 27.4 0.1 7.4e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Lactamase_B_3 PF13483.1 GAK63731.1 - 3e-06 27.0 0.0 9.4e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_32 PF13679.1 GAK63731.1 - 6.5e-05 22.6 0.0 9.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK63731.1 - 0.00076 19.8 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK63731.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAK63731.1 - 0.047 13.0 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.1 GAK63731.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain UPF0052 PF01933.13 GAK63732.1 - 1.3e-40 139.6 0.0 2.7e-27 95.9 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 GalP_UDP_transf PF01087.17 GAK63733.1 - 9.5e-68 227.8 0.9 1.5e-67 227.1 0.6 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 GAK63733.1 - 3.6e-45 153.4 0.0 7.4e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF2781 PF10914.3 GAK63733.1 - 5.3e-35 120.3 8.3 1e-34 119.4 4.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) HIT PF01230.18 GAK63733.1 - 0.0062 17.0 0.1 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 HIT domain BAF1_ABF1 PF04684.8 GAK63733.1 - 0.84 8.4 2.9 1.3 7.7 2.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zn_clus PF00172.13 GAK63734.1 - 1.4e-06 28.0 11.3 2.9e-06 27.0 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 GAK63736.1 - 5.5e-12 46.1 0.0 7.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1682 PF07946.9 GAK63737.1 - 6.2e-78 261.8 0.0 7.2e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) adh_short PF00106.20 GAK63738.1 - 9.5e-18 64.6 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK63738.1 - 2.5e-08 33.8 0.1 5.3e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK63738.1 - 1.5e-05 24.8 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAK63738.1 - 0.00073 19.0 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAK63738.1 - 0.0013 18.8 0.1 0.0025 17.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Pyr_redox_3 PF13738.1 GAK63738.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4302 PF14135.1 GAK63738.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) Pmp3 PF01679.12 GAK63739.1 - 5.4e-12 45.2 6.6 7.9e-12 44.6 4.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Thioredoxin_4 PF13462.1 GAK63740.1 - 3.8e-05 23.7 0.0 0.0011 18.9 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin DSBA PF01323.15 GAK63740.1 - 0.023 14.2 0.1 0.72 9.3 0.0 2.4 3 0 0 3 3 3 0 DSBA-like thioredoxin domain MFS_1 PF07690.11 GAK63741.1 - 3.6e-42 144.3 47.4 5.4e-41 140.4 30.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK63741.1 - 1.5e-15 56.7 12.1 1.5e-15 56.7 8.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAK63741.1 - 8.8e-13 47.3 11.7 8.8e-13 47.3 8.1 2.5 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) ADH_zinc_N PF00107.21 GAK63742.1 - 6.5e-19 67.7 0.2 1.1e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK63742.1 - 1.1e-17 65.0 0.5 1.5e-15 58.1 0.1 2.7 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK63742.1 - 2.3e-12 46.6 0.0 5.7e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 GAK63742.1 - 0.042 13.4 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PHBC_N PF12551.3 GAK63742.1 - 0.043 13.3 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal Peptidase_S10 PF00450.17 GAK63744.1 - 6.9e-115 384.5 0.5 9e-115 384.1 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 GAK63744.1 - 0.0012 18.7 0.0 0.015 15.1 0.0 2.5 3 1 0 3 3 3 1 Alpha/beta hydrolase family Fer2_BFD PF04324.10 GAK63745.1 - 0.1 12.6 5.5 1.3 9.1 0.5 2.3 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Peptidase_S10 PF00450.17 GAK63747.1 - 3e-86 290.1 0.5 4e-86 289.7 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.19 GAK63749.1 - 3.4e-79 266.5 12.8 4.6e-79 266.1 8.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter GTP_EFTU PF00009.22 GAK63749.1 - 3.3e-46 157.1 0.0 5.5e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 GAK63749.1 - 1.5e-36 124.5 0.3 2.7e-36 123.7 0.2 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus MFS_1 PF07690.11 GAK63749.1 - 4.4e-19 68.4 23.9 2.6e-12 46.1 5.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EFG_C PF00679.19 GAK63749.1 - 1.6e-17 63.1 0.0 2.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAK63749.1 - 7.6e-06 25.9 0.2 1.5e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAK63749.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II ICL PF00463.16 GAK63750.1 - 1.6e-186 620.5 0.1 1.9e-186 620.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 GAK63750.1 - 9.3e-11 41.3 0.1 5.6e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.4 GAK63750.1 - 0.034 14.0 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) JHBP PF06585.6 GAK63750.1 - 0.26 10.0 0.1 7.6 5.2 0.0 2.2 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) Methyltransf_16 PF10294.4 GAK63751.1 - 7.4e-16 58.0 0.0 1.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAK63751.1 - 8.5e-05 23.1 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK63751.1 - 0.0028 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAK63751.1 - 0.012 16.0 0.1 0.044 14.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAK63751.1 - 0.038 14.0 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 GAK63751.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_8 PF13450.1 GAK63751.1 - 0.079 12.9 0.1 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pet191_N PF10203.4 GAK63754.1 - 2e-26 91.8 3.2 2.3e-26 91.6 2.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Abhydrolase_5 PF12695.2 GAK63755.1 - 0.03 14.0 0.1 0.052 13.2 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_16 PF00722.16 GAK63756.1 - 4.5e-05 22.8 0.0 7.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 GAK63757.1 - 9.8e-32 110.0 38.8 9.8e-32 110.0 26.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAK63757.1 - 6.1e-06 24.7 0.7 9.4e-06 24.0 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acyl_transf_3 PF01757.17 GAK63758.1 - 2.9e-12 46.0 41.8 3.7e-12 45.7 27.6 2.0 2 0 0 2 2 2 1 Acyltransferase family DUF4381 PF14316.1 GAK63758.1 - 0.037 14.1 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Glyco_tranf_2_3 PF13641.1 GAK63759.1 - 3.2e-26 92.5 0.0 4.8e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAK63759.1 - 2.3e-20 73.1 0.9 2.3e-20 73.1 0.6 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 GAK63759.1 - 1.9e-09 37.0 0.0 3.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAK63759.1 - 2.7e-07 30.4 0.0 5.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 GAK63759.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CoA_binding PF02629.14 GAK63760.1 - 9.3e-20 70.9 1.3 1.6e-19 70.1 0.9 1.4 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 GAK63760.1 - 2.1e-11 43.6 0.0 5.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase GFO_IDH_MocA PF01408.17 GAK63760.1 - 0.00056 20.4 0.1 0.0011 19.4 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Succ_CoA_lig PF13607.1 GAK63760.1 - 0.00077 19.0 0.0 0.0019 17.7 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 GAK63760.1 - 0.015 15.4 0.1 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Ligase_CoA PF00549.14 GAK63761.1 - 1.7e-10 40.7 0.7 2.8e-10 40.0 0.5 1.3 1 0 0 1 1 1 1 CoA-ligase DUF4113 PF13438.1 GAK63761.1 - 0.26 10.8 1.5 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Peptidase_C12 PF01088.16 GAK63762.1 - 2.1e-60 203.5 0.0 2.5e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med10 PF09748.4 GAK63763.1 - 1.6e-20 73.1 0.0 2.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2216 PF10226.4 GAK63763.1 - 0.092 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) PIN_4 PF13638.1 GAK63763.1 - 0.093 12.8 0.0 0.45 10.6 0.0 1.9 1 1 1 2 2 2 0 PIN domain KorB PF08535.5 GAK63763.1 - 0.14 12.3 0.5 1.8 8.7 0.1 2.4 1 1 1 2 2 2 0 KorB domain DUF4593 PF15263.1 GAK63763.1 - 0.22 11.3 6.4 0.41 10.5 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) DUF3275 PF11679.3 GAK63763.1 - 0.33 10.5 1.8 0.56 9.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) CBFD_NFYB_HMF PF00808.18 GAK63764.1 - 2.5e-18 65.8 0.8 4.4e-18 65.0 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2236 PF09995.4 GAK63764.1 - 1.3e-13 50.7 0.1 2.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Histone PF00125.19 GAK63764.1 - 3.7e-09 36.5 0.1 6.9e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF605 PF04652.11 GAK63764.1 - 0.35 10.1 7.6 0.57 9.5 5.3 1.3 1 0 0 1 1 1 0 Vta1 like tRNA-synt_2 PF00152.15 GAK63765.1 - 4.5e-74 249.2 0.0 1.1e-73 247.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 GAK63765.1 - 8.6e-16 57.6 0.1 1.2e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 GAK63765.1 - 4.1e-07 29.7 0.1 1.2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAK63765.1 - 0.0057 15.8 0.3 0.41 9.7 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) His_Phos_1 PF00300.17 GAK63766.1 - 2.4e-16 60.1 0.1 3.5e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_zinc_N PF00107.21 GAK63767.1 - 2.3e-25 88.6 0.0 5.7e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK63767.1 - 7.3e-08 33.3 0.0 1.6e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AFOR_C PF01314.13 GAK63767.1 - 0.00043 19.0 0.2 0.00059 18.6 0.1 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 ELFV_dehydrog PF00208.16 GAK63767.1 - 0.027 14.0 0.3 0.041 13.4 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4384 PF14326.1 GAK63767.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) Orthopox_A47 PF06334.6 GAK63767.1 - 0.18 10.8 0.1 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A47 protein DUF500 PF04366.7 GAK63768.1 - 1.2e-30 105.5 0.0 2.6e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) HAD PF12710.2 GAK63768.1 - 3.4e-06 27.3 0.1 7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIRA_B PF09453.5 GAK63768.1 - 0.52 9.9 2.2 0.83 9.2 0.5 2.1 2 0 0 2 2 2 0 HIRA B motif Phasin PF05597.6 GAK63770.1 - 0.0041 16.8 0.2 0.0053 16.5 0.1 1.1 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3736 PF12540.3 GAK63770.1 - 0.021 15.0 3.8 0.021 15.0 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) ECH PF00378.15 GAK63771.1 - 3.6e-38 131.0 0.1 5.2e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pterin_4a PF01329.14 GAK63771.1 - 0.058 13.1 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase PWI PF01480.12 GAK63772.1 - 6.6e-30 103.0 0.0 9.3e-30 102.5 0.0 1.2 1 0 0 1 1 1 1 PWI domain Methyltransf_18 PF12847.2 GAK63773.1 - 0.0001 22.8 0.0 0.00016 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK63773.1 - 0.0091 15.5 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF4553 PF15090.1 GAK63774.1 - 0.044 12.7 2.0 0.062 12.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) Borrelia_P83 PF05262.6 GAK63774.1 - 0.33 9.1 10.3 0.46 8.6 7.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1682 PF07946.9 GAK63774.1 - 0.41 9.4 6.6 0.56 8.9 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PRP1_N PF06424.7 GAK63775.1 - 0.047 14.0 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF473 PF04322.7 GAK63775.1 - 0.068 12.8 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF473) dCMP_cyt_deam_1 PF00383.17 GAK63776.1 - 4.9e-15 55.0 0.0 1e-14 54.0 0.0 1.5 1 1 1 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 GAK63776.1 - 3.3e-11 43.2 0.4 1.6e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 GAK63776.1 - 0.0018 17.6 1.0 0.027 13.8 0.0 2.3 1 1 0 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases MFS_1 PF07690.11 GAK63777.1 - 5.6e-20 71.3 25.2 2.6e-14 52.7 9.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF427 PF04248.7 GAK63777.1 - 1.4e-14 53.5 0.0 2.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF427) ATG22 PF11700.3 GAK63777.1 - 5.7e-08 31.6 7.8 5.7e-08 31.6 5.4 2.7 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like Na_H_Exchanger PF00999.16 GAK63780.1 - 7.1e-50 169.6 19.2 9.3e-50 169.2 13.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 GAK63780.1 - 0.01 15.7 0.7 0.46 10.4 0.0 2.8 2 0 0 2 2 2 0 YrhC-like protein FGGY_C PF02782.11 GAK63781.1 - 1.1e-15 57.7 0.0 2.5e-15 56.6 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAK63781.1 - 5.1e-11 42.3 0.0 9.2e-06 25.1 0.0 3.7 2 1 1 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain NMO PF03060.10 GAK63782.1 - 7.8e-54 183.0 1.6 1.4e-53 182.2 1.1 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase CoA_transf_3 PF02515.12 GAK63783.1 - 4.9e-64 215.0 0.3 7.5e-64 214.4 0.2 1.3 1 0 0 1 1 1 1 CoA-transferase family III Got1 PF04178.7 GAK63784.1 - 3.5e-19 69.0 25.8 4.5e-19 68.6 17.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Zn_clus PF00172.13 GAK63785.1 - 0.00011 22.0 10.3 0.0002 21.1 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 GAK63785.1 - 0.0035 17.1 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 GAK63785.1 - 0.0072 16.6 0.0 0.024 14.9 0.0 1.8 2 0 0 2 2 2 1 PAS domain WPP PF13943.1 GAK63786.1 - 0.039 14.1 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 WPP domain Allantoicase PF03561.10 GAK63787.1 - 1.1e-84 281.4 0.0 2.1e-44 150.6 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 GAK63787.1 - 6.3e-46 155.7 0.1 9.1e-46 155.2 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase PAF-AH_p_II PF03403.8 GAK63788.1 - 2.1e-47 161.2 0.0 2.3e-43 147.9 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAK63788.1 - 3.8e-10 39.6 0.3 2.1e-09 37.2 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family HAD_2 PF13419.1 GAK63788.1 - 2.7e-09 37.4 0.0 9.6e-08 32.4 0.0 2.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.2 GAK63788.1 - 1.1e-08 35.3 0.3 1.1e-08 35.3 0.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAK63788.1 - 0.016 14.0 0.0 0.23 10.2 0.0 2.3 2 0 0 2 2 2 0 Chlorophyllase enzyme Hydrolase_4 PF12146.3 GAK63788.1 - 0.025 14.4 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 GAK63788.1 - 0.037 13.4 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase PRT_C PF08372.5 GAK63789.1 - 1.2 8.5 3.5 3.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal SNARE PF05739.14 GAK63790.1 - 1.6e-11 43.7 1.1 2.6e-11 43.0 0.8 1.4 1 0 0 1 1 1 1 SNARE domain MIP PF00230.15 GAK63792.1 - 4.7e-43 147.2 2.5 6.3e-43 146.8 1.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein AKNA PF12443.3 GAK63792.1 - 0.0024 17.8 0.8 0.0049 16.8 0.6 1.4 1 0 0 1 1 1 1 AT-hook-containing transcription factor UBN2 PF14223.1 GAK63792.1 - 0.065 13.0 0.7 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Rabaptin PF03528.10 GAK63792.1 - 0.2 11.5 4.0 0.35 10.8 2.8 1.3 1 0 0 1 1 1 0 Rabaptin DNA_pol_B PF00136.16 GAK63793.1 - 2.9e-92 309.9 0.0 4.2e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 GAK63793.1 - 7.3e-20 71.0 0.0 9.2e-11 41.1 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 GAK63793.1 - 2.9e-10 39.9 9.7 5.7e-10 39.0 6.7 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta PSP94 PF05825.6 GAK63793.1 - 3.3 8.0 7.3 2.2 8.6 0.8 2.4 1 1 1 2 2 2 0 Beta-microseminoprotein (PSP-94) MutL_C PF08676.6 GAK63794.1 - 3e-21 75.5 0.0 8.2e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 GAK63794.1 - 9.3e-20 70.2 0.0 2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAK63794.1 - 2.7e-12 46.5 0.0 5.7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAK63794.1 - 4.4e-11 42.4 0.0 1.6e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3585 PF12130.3 GAK63795.1 - 0.0011 18.8 3.9 0.0022 17.8 2.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3585) APG6 PF04111.7 GAK63795.1 - 0.017 14.1 0.6 0.02 13.9 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ScpA_ScpB PF02616.9 GAK63795.1 - 0.039 13.5 0.7 0.046 13.2 0.5 1.1 1 0 0 1 1 1 0 ScpA/B protein RRP7 PF12923.2 GAK63795.1 - 0.041 13.8 0.8 0.058 13.4 0.6 1.2 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) TruD PF01142.13 GAK63795.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) SPT6_acidic PF14632.1 GAK63795.1 - 0.12 12.5 2.5 0.2 11.8 1.7 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DASH_Dad2 PF08654.5 GAK63795.1 - 0.15 12.0 1.1 0.27 11.2 0.2 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 Mit_KHE1 PF10173.4 GAK63795.1 - 0.16 11.8 0.1 0.2 11.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Atg14 PF10186.4 GAK63795.1 - 0.17 10.7 1.2 0.23 10.3 0.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ERG2_Sigma1R PF04622.7 GAK63796.1 - 5.9e-98 326.4 0.1 6.8e-98 326.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Rhodanese PF00581.15 GAK63797.1 - 7.2e-08 32.7 0.0 1.8e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain KduI PF04962.7 GAK63797.1 - 0.014 14.4 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family AMP-binding PF00501.23 GAK63798.1 - 9.2e-79 264.7 0.3 1.5e-51 175.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 GAK63798.1 - 6.6e-09 36.5 0.0 3.5e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.23 GAK63799.1 - 1.4e-09 37.6 1.4 3.6e-09 36.3 1.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAK63799.1 - 0.00015 21.6 0.0 0.00071 19.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EHN PF06441.7 GAK63800.1 - 3e-32 110.8 0.1 5.4e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAK63800.1 - 5e-08 33.1 0.1 3.5e-07 30.3 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK63800.1 - 0.00097 18.7 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_L37 PF08561.5 GAK63801.1 - 6.5e-29 99.3 5.0 2.3e-27 94.3 3.4 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 NARP1 PF12569.3 GAK63801.1 - 0.13 10.9 8.3 0.17 10.6 5.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CUE PF02845.11 GAK63802.1 - 3.1e-11 42.5 0.0 6.3e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 CUE domain Peptidase_M19 PF01244.16 GAK63803.1 - 2.3e-85 286.3 0.0 3.2e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Abhydrolase_6 PF12697.2 GAK63803.1 - 4.7e-15 56.0 0.7 1.8e-14 54.2 0.5 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK63803.1 - 0.023 14.4 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_31 PF01055.21 GAK63804.1 - 2.1e-80 270.7 0.0 2.8e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAK63804.1 - 2.4e-08 33.6 0.0 7.6e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 GAK63805.1 - 9.7e-35 119.9 21.6 1.2e-34 119.6 15.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_32N PF00251.15 GAK63806.1 - 1.1e-86 290.9 7.0 1.7e-86 290.3 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAK63806.1 - 9.2e-07 29.1 0.1 2.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_88 PF07470.8 GAK63807.1 - 1.2e-67 228.3 1.1 1.6e-67 227.9 0.7 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 peroxidase PF00141.18 GAK63810.1 - 5.1e-50 170.1 0.0 7.7e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase PXA PF02194.10 GAK63811.1 - 2.8e-17 62.9 0.1 6.9e-16 58.3 0.0 2.9 4 0 0 4 4 4 1 PXA domain Nexin_C PF08628.7 GAK63811.1 - 0.0045 17.0 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal Acetyltransf_3 PF13302.1 GAK63812.1 - 2.4e-14 53.6 0.0 4.1e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAK63812.1 - 3.9e-05 23.6 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAK63812.1 - 0.0014 18.5 0.0 0.0046 16.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain UvdE PF03851.9 GAK63813.1 - 1.5e-85 286.5 0.0 2.1e-85 286.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE Hamartin PF04388.7 GAK63813.1 - 2.5 6.6 4.5 3.7 6.1 3.1 1.2 1 0 0 1 1 1 0 Hamartin protein RCC1 PF00415.13 GAK63814.1 - 1.1e-24 86.4 18.2 7.4e-11 42.0 0.0 8.5 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAK63814.1 - 3.1e-14 52.1 13.5 9e-09 34.7 0.3 6.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat NHL PF01436.16 GAK63814.1 - 0.25 11.3 1.6 2.5 8.2 0.4 2.7 2 0 0 2 2 2 0 NHL repeat 4HBT PF03061.17 GAK63816.1 - 3.1e-10 40.0 0.0 5.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily N6-adenineMlase PF10237.4 GAK63817.1 - 3.4e-31 108.0 0.0 6.7e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 GAK63817.1 - 0.068 13.1 0.2 0.13 12.2 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain PRELI PF04707.9 GAK63818.1 - 3.8e-40 137.0 0.0 4.7e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Glyco_hydro_47 PF01532.15 GAK63819.1 - 1.7e-125 419.2 0.0 2.1e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TMEM154 PF15102.1 GAK63820.1 - 0.25 11.0 2.0 0.35 10.5 0.1 2.1 2 1 0 2 2 2 0 TMEM154 protein family WES_acyltransf PF03007.11 GAK63821.1 - 9.2e-13 48.3 0.0 9.2e-13 48.3 0.0 2.4 2 2 1 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 GAK63821.1 - 0.031 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Mrr_cat_2 PF13156.1 GAK63821.1 - 0.038 13.8 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease DSBA PF01323.15 GAK63823.1 - 1.3e-05 24.8 0.1 3.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.20 GAK63824.1 - 4.5e-11 42.9 0.0 8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK63824.1 - 1.7e-05 24.7 0.0 2.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK63824.1 - 0.0069 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 GAK63824.1 - 0.027 13.5 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans_2 PF11951.3 GAK63825.1 - 1.9e-13 49.7 0.1 5.5e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK63825.1 - 1.4e-09 37.6 11.8 2.4e-09 36.9 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GalKase_gal_bdg PF10509.4 GAK63826.1 - 1.3e-21 75.5 0.0 2.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 GAK63826.1 - 5.1e-12 45.6 0.6 1.6e-11 44.0 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAK63826.1 - 7e-12 45.3 0.2 3.7e-10 39.8 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal Fungal_trans PF04082.13 GAK63827.1 - 4.4e-06 25.7 0.1 7.8e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK63827.1 - 1.6e-05 24.6 11.1 3.1e-05 23.7 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAK63828.1 - 1.6e-34 119.1 53.4 4.8e-34 117.6 36.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK63828.1 - 1.2e-10 40.5 26.5 1.4e-10 40.3 9.9 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter PsbT PF01405.12 GAK63828.1 - 0.057 13.0 0.3 0.25 10.9 0.2 2.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein FPN1 PF06963.7 GAK63829.1 - 9.5e-136 452.6 11.4 1.2e-135 452.2 7.9 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Acyl-CoA_ox_N PF14749.1 GAK63830.1 - 6e-20 71.8 0.9 1.2e-19 70.8 0.6 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.14 GAK63830.1 - 4e-19 68.7 0.0 7e-18 64.6 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 GAK63830.1 - 1.5e-08 34.0 0.3 3.3e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAK63830.1 - 2e-05 24.7 0.1 5.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.9 GAK63831.1 - 5e-10 39.6 1.5 0.00035 20.5 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK63831.1 - 1.6e-07 31.6 0.4 1.6e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAK63831.1 - 9.7e-06 24.7 0.1 3.2e-05 23.0 0.0 1.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAK63831.1 - 1.5e-05 24.0 5.5 0.002 17.0 0.2 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK63831.1 - 0.00042 18.9 3.9 0.11 10.9 0.1 3.3 3 1 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 GAK63831.1 - 0.00047 19.3 0.2 0.012 14.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 GAK63831.1 - 0.00055 20.0 0.4 0.37 10.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK63831.1 - 0.00064 18.7 1.2 0.095 11.5 0.1 2.9 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAK63831.1 - 0.021 14.8 1.0 0.07 13.1 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAK63831.1 - 0.03 12.9 0.3 0.03 12.9 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAK63831.1 - 0.34 10.6 3.5 35 4.1 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Arrestin_C PF02752.17 GAK63832.1 - 5.5e-19 68.6 0.0 3e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAK63832.1 - 5.3e-10 39.3 0.0 8e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Sgf11 PF08209.6 GAK63833.1 - 8.5e-15 53.7 0.5 1.7e-14 52.7 0.4 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 GAK63833.1 - 4.6 7.0 5.4 0.5 10.0 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF2418 PF10332.4 GAK63834.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) GFA PF04828.9 GAK63835.1 - 8.5e-21 73.7 0.2 1.1e-20 73.3 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 GAK63835.1 - 0.0064 16.2 2.4 0.07 12.9 0.0 2.2 2 0 0 2 2 2 1 Double zinc ribbon FdhE PF04216.7 GAK63835.1 - 0.012 15.3 1.3 0.21 11.2 0.1 2.1 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation Nudix_N_2 PF14803.1 GAK63835.1 - 0.034 13.8 0.1 0.034 13.8 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zf-LITAF-like PF10601.4 GAK63835.1 - 0.039 13.8 3.4 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Lar_restr_allev PF14354.1 GAK63835.1 - 0.04 14.2 2.5 1.4 9.2 0.1 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar NOB1_Zn_bind PF08772.6 GAK63835.1 - 0.065 13.0 0.1 0.065 13.0 0.1 2.5 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 GAK63835.1 - 0.079 12.1 0.3 0.079 12.1 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 GAK63835.1 - 0.084 12.5 0.9 0.084 12.5 0.7 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_2 PF13240.1 GAK63835.1 - 0.21 11.1 0.3 0.21 11.1 0.2 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 GAK63835.1 - 2.2 8.2 5.8 0.93 9.4 0.1 2.5 2 1 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 GAK63835.1 - 3.6 7.3 11.4 0.29 10.8 3.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 GAK63835.1 - 5.6 6.5 9.2 0.5 9.9 0.3 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_5 PF13719.1 GAK63835.1 - 6.2 6.4 11.8 0.52 9.9 3.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Cyanate_lyase PF02560.9 GAK63836.1 - 2.4e-33 113.4 0.0 3.9e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 GAK63836.1 - 0.00088 19.4 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 GAK63836.1 - 0.00095 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix DUF373 PF04123.8 GAK63836.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SNase PF00565.12 GAK63837.1 - 3.3e-43 146.3 0.2 3.1e-18 65.9 0.0 6.3 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 GAK63837.1 - 4.4e-17 62.0 0.0 9.7e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 GAK63837.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zn_clus PF00172.13 GAK63838.1 - 3.7e-07 29.9 6.7 7.3e-07 28.9 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.7 GAK63838.1 - 0.13 11.9 0.0 0.42 10.2 0.0 1.9 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Neur_chan_memb PF02932.11 GAK63839.1 - 0.065 13.1 0.4 0.091 12.6 0.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1183 PF06682.7 GAK63839.1 - 9.5 5.7 25.0 15 5.1 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) NAD_binding_2 PF03446.10 GAK63840.1 - 1.3e-36 125.8 2.4 2.2e-36 125.1 1.6 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAK63840.1 - 5.2e-32 110.4 2.4 6e-32 110.2 0.6 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Collagen PF01391.13 GAK63840.1 - 5.5e-10 38.6 84.6 0.00025 20.5 18.1 4.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) F420_oxidored PF03807.12 GAK63840.1 - 0.00015 22.0 0.6 0.00038 20.8 0.4 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAK63840.1 - 0.00029 20.5 1.0 0.00051 19.7 0.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAK63840.1 - 0.003 16.7 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CAP_N PF01213.14 GAK63840.1 - 0.97 8.6 5.6 1.2 8.3 3.3 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_26 PF13659.1 GAK63842.1 - 5.3e-13 49.0 0.3 8.3e-13 48.3 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK63842.1 - 3.3e-11 42.8 0.1 5.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 GAK63842.1 - 1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 GAK63842.1 - 8.5e-06 26.5 0.0 6.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK63842.1 - 5.5e-05 23.4 0.0 0.00023 21.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK63842.1 - 0.00027 21.4 0.1 0.00073 20.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK63842.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_7 PF03441.9 GAK63842.1 - 0.021 14.0 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase Gly_kinase PF02595.10 GAK63842.1 - 0.028 13.1 0.1 0.05 12.2 0.1 1.4 1 0 0 1 1 1 0 Glycerate kinase family PCMT PF01135.14 GAK63842.1 - 0.033 13.7 0.1 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 GAK63842.1 - 0.076 13.4 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 GAK63842.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) p450 PF00067.17 GAK63843.1 - 5.7e-61 206.4 0.0 1.4e-60 205.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 GAK63844.1 - 7e-16 58.4 1.8 1e-11 44.7 0.5 2.4 2 0 0 2 2 2 2 Acyl transferase domain MFS_1 PF07690.11 GAK63845.1 - 1.6e-35 122.4 75.5 1.6e-30 106.0 39.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 GAK63845.1 - 1.1 7.7 13.6 0.75 8.3 0.0 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Wzy_C PF04932.10 GAK63845.1 - 4.6 7.0 16.3 8 6.2 2.1 3.9 2 1 1 3 3 3 0 O-Antigen ligase CoA_transf_3 PF02515.12 GAK63846.1 - 0.15 11.3 0.8 0.36 10.0 0.3 1.8 2 0 0 2 2 2 0 CoA-transferase family III PIRT PF15099.1 GAK63846.1 - 0.36 10.0 3.8 1 8.5 2.6 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family ADH_N PF08240.7 GAK63847.1 - 4.6e-29 100.3 0.6 7.6e-29 99.6 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK63847.1 - 9.6e-27 93.0 0.5 1.5e-26 92.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK63847.1 - 4.1e-08 34.1 0.6 1.2e-07 32.6 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 GAK63850.1 - 3.2e-09 36.1 0.1 1.4e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAK63850.1 - 5.2e-09 35.5 0.3 9e-08 31.5 0.1 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAK63850.1 - 2.8e-05 23.7 2.9 0.00011 21.7 2.0 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 GAK63850.1 - 0.00075 19.1 4.4 0.0035 16.9 0.3 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 GAK63850.1 - 0.004 15.6 0.3 0.024 13.0 0.2 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 GAK63850.1 - 0.051 13.4 1.1 0.52 10.1 0.0 2.8 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain GFO_IDH_MocA PF01408.17 GAK63852.1 - 7.8e-22 78.0 0.0 1.3e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAK63852.1 - 0.026 14.8 0.0 0.069 13.4 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CRCB PF02537.10 GAK63853.1 - 3.9e-32 110.5 17.7 1.1e-18 67.2 4.3 2.6 2 1 0 2 2 2 2 CrcB-like protein Acetyltransf_8 PF13523.1 GAK63854.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAK63854.1 - 0.015 15.2 0.3 0.024 14.6 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family EB PF01683.13 GAK63855.1 - 4.7 7.3 13.9 1.5e+02 2.5 9.6 2.2 1 1 0 1 1 1 0 EB module zf-ZPR1 PF03367.8 GAK63856.1 - 0.011 14.9 0.5 0.02 14.0 0.4 1.3 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Methyltrans_RNA PF04452.9 GAK63856.1 - 0.12 11.5 0.2 0.67 9.0 0.0 1.9 2 0 0 2 2 2 0 RNA methyltransferase DDE_Tnp_4 PF13359.1 GAK63857.1 - 5.3e-17 61.8 0.0 7.2e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SNF2_N PF00176.18 GAK63859.1 - 7.8e-42 143.0 0.0 1.6e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 GAK63859.1 - 2.3e-06 27.1 9.9 4e-06 26.4 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK63859.1 - 2.1e-05 24.4 13.1 3.7e-05 23.6 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK63859.1 - 4.2e-05 23.1 12.9 7.2e-05 22.3 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 GAK63859.1 - 6.1e-05 22.8 0.0 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 GAK63859.1 - 0.00011 21.8 12.8 0.0002 21.0 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAK63859.1 - 0.00021 20.9 12.5 0.00035 20.2 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAK63859.1 - 0.13 12.1 10.4 0.25 11.2 7.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 GAK63859.1 - 0.56 9.7 5.7 1.9 8.0 3.9 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.1 GAK63859.1 - 0.57 9.9 4.1 1.5 8.6 2.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF4501 PF14946.1 GAK63859.1 - 0.76 9.2 4.5 1.6 8.2 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) DUF2890 PF11081.3 GAK63860.1 - 0.028 14.4 0.6 0.028 14.4 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2890) M20_dimer PF07687.9 GAK63861.1 - 2.1e-11 43.5 1.4 2.3e-11 43.4 0.1 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 GAK63861.1 - 5.2e-09 35.8 0.8 8.4e-09 35.1 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 NMO PF03060.10 GAK63862.1 - 0.073 12.2 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase NMO PF03060.10 GAK63863.1 - 6.1e-46 157.0 3.1 2.7e-45 154.9 2.2 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase DUF1275 PF06912.6 GAK63863.1 - 1.6e-25 89.5 10.1 3e-25 88.6 7.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) IMPDH PF00478.20 GAK63863.1 - 1e-08 34.4 1.1 0.00073 18.5 0.6 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DUF1109 PF06532.6 GAK63863.1 - 0.0021 17.5 2.2 0.0021 17.5 1.5 2.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1109) FMN_dh PF01070.13 GAK63863.1 - 0.0049 15.7 0.4 0.012 14.4 0.3 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 GAK63863.1 - 0.021 14.0 0.1 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.12 GAK63863.1 - 0.042 12.9 0.1 0.081 12.0 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Abhydrolase_4 PF08386.5 GAK63864.1 - 6.2e-21 74.2 0.0 1.2e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 GAK63864.1 - 3.7e-14 52.8 0.0 6.2e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK63864.1 - 7.7e-07 29.2 0.1 7.6e-06 25.9 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family F-box-like PF12937.2 GAK63865.1 - 6.3e-10 38.6 1.4 3e-09 36.4 0.9 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK63865.1 - 0.0018 17.8 0.1 0.014 15.0 0.1 2.3 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.11 GAK63866.1 - 6.9e-42 143.4 34.3 6.9e-42 143.4 23.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAK63866.1 - 1.1e-11 43.7 1.6 1.7e-11 43.0 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAK63866.1 - 3.2e-11 42.4 27.4 2.2e-09 36.4 18.8 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4042 PF13251.1 GAK63869.1 - 6.3e-14 51.8 10.9 6.8e-09 35.4 0.2 5.7 6 0 0 6 6 6 3 Domain of unknown function (DUF4042) HEAT PF02985.17 GAK63869.1 - 4.5e-05 23.1 16.9 0.29 11.3 0.0 7.9 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.18 GAK63869.1 - 0.55 10.1 4.5 61 3.6 0.2 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAK63869.1 - 0.78 10.0 52.7 0.22 11.8 0.8 7.8 5 2 2 7 7 7 0 HEAT repeats Pterin_4a PF01329.14 GAK63870.1 - 6e-27 93.2 0.4 8.4e-27 92.7 0.3 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Sulfate_tra_GLY PF13792.1 GAK63871.1 - 0.0034 17.0 0.1 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif LRR_6 PF13516.1 GAK63872.1 - 0.0022 17.8 7.3 13 6.2 0.0 5.7 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.2 GAK63872.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 GAK63872.1 - 0.073 12.7 8.1 4.2 7.1 0.1 4.8 5 1 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAK63872.1 - 0.11 12.5 6.7 8 6.9 0.1 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat Abhydrolase_5 PF12695.2 GAK63873.1 - 6.2e-18 64.9 0.3 9.6e-18 64.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK63873.1 - 3.1e-13 50.1 4.7 5.9e-13 49.2 3.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAK63873.1 - 9.8e-10 38.3 0.6 1.6e-09 37.6 0.4 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 GAK63873.1 - 3.7e-08 33.2 0.3 2.8e-07 30.3 0.1 2.2 2 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 GAK63873.1 - 0.0002 20.8 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 GAK63873.1 - 0.00033 19.9 1.2 0.0061 15.7 0.4 2.5 1 1 1 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 GAK63873.1 - 0.0026 16.5 0.2 0.0038 15.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.15 GAK63873.1 - 0.0073 15.7 0.4 0.049 13.0 0.2 2.0 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 GAK63873.1 - 0.015 15.1 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase BAAT_C PF08840.6 GAK63873.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.7 GAK63873.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) HMGL-like PF00682.14 GAK63874.1 - 1.8e-42 145.6 0.4 3.5e-42 144.7 0.3 1.4 1 1 0 1 1 1 1 HMGL-like PGG PF13962.1 GAK63875.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1018 PF06252.7 GAK63875.1 - 0.066 13.7 0.3 3 8.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) DUF3074 PF11274.3 GAK63876.1 - 4.4e-50 169.8 0.1 5.9e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ACC_epsilon PF13822.1 GAK63878.1 - 0.89 9.9 4.7 0.73 10.2 1.6 1.9 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ham1p_like PF01725.11 GAK63879.1 - 1.4e-50 171.3 0.0 1.6e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family MFS_1 PF07690.11 GAK63880.1 - 3e-26 91.9 24.1 3.8e-26 91.6 16.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DAHP_synth_2 PF01474.11 GAK63881.1 - 3.9e-157 523.1 0.0 4.6e-112 374.5 0.0 2.0 2 0 0 2 2 2 2 Class-II DAHP synthetase family PRT_C PF08372.5 GAK63883.1 - 4.7e-05 22.9 0.3 0.16 11.4 0.0 2.6 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal DUF3292 PF11696.3 GAK63883.1 - 0.00017 19.5 0.2 0.00017 19.5 0.1 2.9 5 0 0 5 5 5 1 Protein of unknown function (DUF3292) AAA_17 PF13207.1 GAK63883.1 - 0.00048 20.9 0.0 0.0052 17.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 GAK63883.1 - 0.012 14.4 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DUF2075 PF09848.4 GAK63883.1 - 0.022 13.7 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Reticulon PF02453.12 GAK63883.1 - 0.022 14.4 8.2 0.43 10.1 0.5 3.0 3 0 0 3 3 3 0 Reticulon AAA_18 PF13238.1 GAK63883.1 - 0.029 14.6 0.0 0.094 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAK63883.1 - 0.04 12.7 0.1 0.57 8.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 GAK63883.1 - 0.051 13.3 0.1 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 GAK63883.1 - 0.34 10.7 3.9 1.6 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Methyltransf_23 PF13489.1 GAK63884.1 - 8e-06 25.6 0.0 2.4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK63884.1 - 0.0037 16.8 0.0 3.8 7.0 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Rhodanese PF00581.15 GAK63884.1 - 0.021 15.1 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain Methyltransf_18 PF12847.2 GAK63884.1 - 0.028 14.9 1.2 0.74 10.4 0.8 2.8 1 1 0 1 1 1 0 Methyltransferase domain PRK PF00485.13 GAK63885.1 - 9.4e-53 178.6 0.0 1.9e-52 177.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 GAK63885.1 - 6.8e-44 149.5 0.1 1.2e-41 142.2 0.0 2.3 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 GAK63885.1 - 3e-08 34.0 0.0 5.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK63885.1 - 2.8e-06 28.1 0.0 5.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 GAK63885.1 - 0.00018 20.9 0.0 0.00045 19.6 0.0 1.6 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 GAK63885.1 - 0.00022 21.1 0.0 0.0007 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 GAK63885.1 - 0.0004 20.0 0.0 0.00082 19.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 GAK63885.1 - 0.0045 16.7 0.3 5.6 6.8 0.1 3.6 3 0 0 3 3 3 1 Part of AAA domain Zeta_toxin PF06414.7 GAK63885.1 - 0.069 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 GAK63885.1 - 0.14 12.1 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cyt-b5 PF00173.23 GAK63886.1 - 4e-10 39.3 0.0 6.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF667 PF05018.8 GAK63887.1 - 2.5e-10 39.9 0.0 0.00027 20.2 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF667) hSac2 PF12456.3 GAK63888.1 - 3.5e-29 100.5 0.0 5.9e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Glyco_hydro_108 PF05838.7 GAK63888.1 - 0.062 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase 108 Syja_N PF02383.13 GAK63889.1 - 4.7e-88 295.0 0.0 9.7e-88 293.9 0.0 1.5 1 1 0 1 1 1 1 SacI homology domain Macoilin PF09726.4 GAK63889.1 - 4 5.5 11.8 12 4.0 8.2 1.6 1 1 0 1 1 1 0 Transmembrane protein Polysacc_deac_1 PF01522.16 GAK63890.1 - 6.1e-30 103.4 0.0 1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Serglycin PF04360.7 GAK63890.1 - 6.3 6.5 6.6 1 9.0 0.6 2.2 2 0 0 2 2 2 0 Serglycin NUDE_C PF04880.8 GAK63890.1 - 7.6 6.8 11.7 0.18 12.1 0.5 2.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF2962 PF11176.3 GAK63891.1 - 5.6e-41 139.6 0.7 7.3e-40 136.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2962) RTA1 PF04479.8 GAK63892.1 - 5.3e-30 104.5 9.0 1.5e-25 89.9 2.2 2.3 2 0 0 2 2 2 2 RTA1 like protein DUF350 PF03994.9 GAK63892.1 - 0.0063 16.2 0.7 0.0063 16.2 0.5 3.6 3 1 0 3 3 3 1 Domain of Unknown Function (DUF350) Zn_clus PF00172.13 GAK63893.1 - 0.0036 17.1 7.7 0.0078 16.1 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 GAK63894.1 - 6.1e-42 143.7 0.1 1.1e-41 142.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK63894.1 - 1.6e-21 77.1 0.3 9.4e-21 74.6 0.0 2.3 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAK63894.1 - 2.7e-06 26.5 3.1 0.025 13.4 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 GAK63894.1 - 0.00014 21.0 0.6 0.00022 20.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAK63894.1 - 0.0011 18.8 0.4 0.014 15.2 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK63894.1 - 0.0021 17.0 3.2 0.26 10.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK63894.1 - 0.045 13.7 1.5 0.13 12.3 1.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 GAK63894.1 - 0.064 13.0 0.9 0.41 10.4 1.1 2.0 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 GAK63894.1 - 0.12 11.4 0.4 0.21 10.6 0.3 1.3 1 0 0 1 1 1 0 Thi4 family MatE PF01554.13 GAK63895.1 - 1.4e-52 177.5 26.8 2.1e-31 108.7 6.7 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 GAK63895.1 - 1.2e-07 31.6 9.5 1.2e-07 31.6 6.6 3.7 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MGC-24 PF05283.6 GAK63895.1 - 1.1 8.9 3.4 9.3 5.9 0.2 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Acetyltransf_1 PF00583.19 GAK63896.1 - 2.1e-12 46.8 0.1 3.1e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK63896.1 - 4e-11 42.9 0.0 5.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAK63896.1 - 2.7e-06 27.4 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAK63896.1 - 3.7e-05 23.9 0.0 4.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAK63896.1 - 0.00019 21.4 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAK63896.1 - 0.0068 16.2 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Amidohydro_2 PF04909.9 GAK63897.1 - 1.2e-40 139.8 1.5 1.2e-40 139.8 1.0 1.5 2 0 0 2 2 2 1 Amidohydrolase DUF2456 PF10445.4 GAK63898.1 - 0.13 12.1 0.2 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) SF3b1 PF08920.5 GAK63899.1 - 1.8e-27 96.1 0.1 1.8e-27 96.1 0.1 2.6 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 GAK63899.1 - 1.7e-16 60.2 5.5 2.5e-05 24.4 0.0 8.1 6 2 4 10 10 10 6 HEAT repeats HEAT_EZ PF13513.1 GAK63899.1 - 3.6e-09 36.8 6.6 0.34 11.4 0.0 8.1 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 GAK63899.1 - 4.1e-08 32.6 7.6 0.39 10.9 0.0 8.8 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.15 GAK63899.1 - 1e-06 27.3 1.4 0.093 11.0 0.0 3.9 2 2 2 4 4 4 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 GAK63899.1 - 7.6e-06 26.2 0.3 1.6 9.1 0.0 4.8 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAK63899.1 - 0.00037 19.9 0.4 0.25 10.6 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal Dopey_N PF04118.9 GAK63899.1 - 0.0095 14.7 0.4 0.069 11.9 0.0 2.5 3 0 0 3 3 3 1 Dopey, N-terminal TIP120 PF08623.5 GAK63899.1 - 0.025 14.1 0.6 2.5 7.6 0.0 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) MMS19_N PF14500.1 GAK63899.1 - 0.029 13.6 0.4 23 4.1 0.0 3.9 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II MOZ_SAS PF01853.13 GAK63900.1 - 2.6e-85 284.4 0.8 4e-85 283.8 0.5 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 GAK63900.1 - 5.3e-24 83.6 0.0 1.1e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 GAK63900.1 - 0.05 13.9 1.4 0.14 12.5 0.9 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2945 PF11160.3 GAK63901.1 - 0.0083 15.9 4.1 0.014 15.2 2.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) SIR2 PF02146.12 GAK63902.1 - 1.4e-30 106.3 0.0 2.4e-18 66.5 0.0 2.1 2 0 0 2 2 2 2 Sir2 family T2SJ PF11612.3 GAK63902.1 - 0.096 12.4 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J Na_Ca_ex PF01699.19 GAK63903.1 - 4.7e-30 104.0 11.5 7.5e-16 58.0 0.0 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2360 PF10152.4 GAK63903.1 - 2.1 8.5 11.7 0.49 10.6 0.1 2.4 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Ribosomal_S8e PF01201.17 GAK63905.1 - 3.7e-37 127.4 7.7 5.7e-36 123.5 5.3 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 GAK63905.1 - 0.056 13.3 3.5 0.058 13.3 0.9 1.8 1 1 1 2 2 2 0 Mer2 AAA_13 PF13166.1 GAK63905.1 - 0.67 8.3 5.7 0.83 8.0 4.0 1.0 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 GAK63905.1 - 5.6 5.1 10.9 7.4 4.7 7.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Yip1 PF04893.12 GAK63906.1 - 1.9e-09 37.2 11.7 3.7e-09 36.3 8.1 1.5 1 0 0 1 1 1 1 Yip1 domain DUF2428 PF10350.4 GAK63907.1 - 5.6e-53 179.5 0.1 1.5e-52 178.2 0.0 1.8 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) PIGA PF08288.7 GAK63907.1 - 7.7e-43 144.7 0.0 3.2e-42 142.8 0.1 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 GAK63907.1 - 2.3e-24 85.7 0.0 4.4e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAK63907.1 - 9.7e-15 54.7 3.9 1.5e-14 54.0 0.1 2.9 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 GAK63907.1 - 1.1e-11 44.9 0.0 3.4e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 HEAT PF02985.17 GAK63907.1 - 3.7e-05 23.4 9.3 1 9.5 0.1 6.0 5 0 0 5 5 5 2 HEAT repeat Glyco_trans_1_2 PF13524.1 GAK63907.1 - 0.0002 21.5 0.0 0.00075 19.7 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 HEAT_EZ PF13513.1 GAK63907.1 - 1.2 9.7 11.9 25 5.5 1.7 6.1 5 1 1 6 6 6 0 HEAT-like repeat DUF1767 PF08585.7 GAK63908.1 - 1.9e-14 53.6 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) tRNA-synt_2c PF01411.14 GAK63909.1 - 1.7e-212 706.6 0.0 2.2e-212 706.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAK63909.1 - 1e-16 60.4 0.2 2.5e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 GAK63909.1 - 3.1e-06 26.8 1.9 1.1e-05 24.9 1.3 2.0 1 0 0 1 1 1 1 DHHA1 domain IMD PF08397.6 GAK63909.1 - 0.28 10.4 5.8 0.059 12.6 1.1 1.9 2 0 0 2 2 2 0 IRSp53/MIM homology domain YscJ_FliF PF01514.12 GAK63910.1 - 0.0044 16.1 0.2 0.0044 16.1 0.2 1.8 2 0 0 2 2 2 1 Secretory protein of YscJ/FliF family PP2C PF00481.16 GAK63911.1 - 1e-54 185.6 0.0 2.5e-54 184.3 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 GAK63911.1 - 1.6e-52 174.3 69.0 4.6e-08 32.5 0.7 13.6 7 4 8 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK63911.1 - 3.5e-47 157.9 59.7 9.7e-09 34.8 1.4 8.9 5 2 1 8 8 8 7 Leucine rich repeat Guanylate_cyc PF00211.15 GAK63911.1 - 9.9e-25 86.9 0.0 1.9e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 GAK63911.1 - 2e-23 78.8 66.1 0.082 12.9 0.0 20.0 20 1 1 21 21 21 10 Leucine Rich Repeat RA PF00788.18 GAK63911.1 - 1.3e-10 41.5 0.0 3.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 GAK63911.1 - 2.5e-07 29.7 60.5 0.78 10.2 0.0 17.8 20 0 0 20 20 19 4 Leucine rich repeat LRR_6 PF13516.1 GAK63911.1 - 2.3e-05 23.9 56.3 3.3 8.0 0.0 16.4 19 1 0 19 19 17 2 Leucine Rich repeat LRR_9 PF14580.1 GAK63911.1 - 2.4e-05 23.9 19.8 0.24 10.9 0.5 5.5 2 1 3 6 6 6 5 Leucine-rich repeat LRR_5 PF13306.1 GAK63911.1 - 0.00028 20.6 0.5 9.8 5.8 0.1 4.3 3 1 1 4 4 4 1 Leucine rich repeats (6 copies) Integrin_beta PF00362.13 GAK63911.1 - 0.28 10.0 0.0 0.49 9.2 0.0 1.3 1 0 0 1 1 1 0 Integrin, beta chain PRA1 PF03208.14 GAK63912.1 - 7.9e-39 132.4 0.8 9.2e-39 132.2 0.6 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2306 PF10067.4 GAK63912.1 - 0.053 13.6 0.4 0.097 12.7 0.3 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) Tetraspannin PF00335.15 GAK63912.1 - 4.5 6.4 7.8 6.8 5.9 5.4 1.3 1 0 0 1 1 1 0 Tetraspanin family FAD_binding_3 PF01494.14 GAK63913.1 - 4.5e-22 78.5 0.0 1.5e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 GAK63913.1 - 4.3e-05 22.3 0.8 0.0018 16.9 0.0 2.1 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 GAK63913.1 - 0.00013 21.9 0.9 0.00034 20.5 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAK63913.1 - 0.00033 20.9 0.4 0.001 19.4 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK63913.1 - 0.0013 17.7 2.8 0.017 14.0 1.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK63913.1 - 0.0022 17.7 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAK63913.1 - 0.0029 16.5 2.2 0.005 15.7 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 GAK63913.1 - 0.0094 15.0 0.1 0.31 10.0 0.0 2.7 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 GAK63913.1 - 0.015 15.1 0.9 0.027 14.3 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK63913.1 - 0.046 12.1 0.8 0.069 11.5 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein SE PF08491.5 GAK63913.1 - 0.071 11.9 0.0 3.2 6.5 0.0 2.4 2 1 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.1 GAK63913.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAK63913.1 - 0.11 12.1 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 GAK63913.1 - 0.14 11.0 0.2 6 5.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 GAK63913.1 - 0.14 10.9 1.2 0.21 10.3 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAK63913.1 - 0.25 10.9 0.4 0.54 9.8 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_2 PF00703.16 GAK63914.1 - 0.0061 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 ubiquitin PF00240.18 GAK63915.1 - 8.4e-19 66.7 0.2 1.3e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 GAK63915.1 - 7.4e-18 63.8 8.8 2.5e-11 43.0 0.3 2.7 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.6 GAK63915.1 - 9.4e-17 60.2 5.2 1.8e-16 59.2 3.6 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 GAK63915.1 - 1.2e-06 28.0 0.4 2e-06 27.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 GAK63915.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 GAK63915.1 - 0.027 13.9 0.0 0.16 11.5 0.0 2.3 3 0 0 3 3 3 0 UBA-like domain UBA_3 PF09288.5 GAK63915.1 - 0.048 13.2 0.2 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain RAP1 PF07218.6 GAK63915.1 - 7.1 4.5 8.8 10 4.0 6.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NfeD PF01957.13 GAK63917.1 - 0.1 12.7 0.7 0.23 11.6 0.2 1.8 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding SAP PF02037.22 GAK63918.1 - 4.6e-12 45.1 0.3 1.2e-11 43.8 0.2 1.8 1 0 0 1 1 1 1 SAP domain CCT_2 PF09425.5 GAK63918.1 - 0.018 14.5 0.1 0.079 12.5 0.1 2.1 1 0 0 1 1 1 0 Divergent CCT motif Enkurin PF13864.1 GAK63918.1 - 0.43 10.8 8.8 0.79 9.9 3.3 2.4 2 0 0 2 2 2 0 Calmodulin-binding Muskelin_N PF06588.6 GAK63919.1 - 2.8e-53 180.5 0.2 8.7e-21 74.5 0.0 3.5 3 1 0 3 3 3 3 Muskelin N-terminus Kelch_3 PF13415.1 GAK63919.1 - 3e-20 71.8 12.1 1.5e-07 31.3 0.1 7.6 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 GAK63919.1 - 1.7e-17 62.9 8.0 1.7e-06 27.6 0.2 6.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 GAK63919.1 - 1.1e-14 53.9 3.4 0.004 17.0 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 GAK63919.1 - 3.1e-14 52.4 1.3 0.0094 16.0 0.0 7.2 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.20 GAK63919.1 - 2.2e-09 36.7 1.1 0.0042 16.6 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 GAK63919.1 - 0.00052 19.6 6.3 0.036 13.8 0.2 4.6 5 0 0 5 5 5 1 Kelch motif Glyco_hydro_30 PF02055.11 GAK63921.1 - 9.8e-23 80.1 0.9 1.5e-22 79.5 0.6 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 GAK63921.1 - 0.00094 18.2 0.0 0.022 13.7 0.0 2.1 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.10 GAK63921.1 - 0.0013 16.9 0.2 0.0024 16.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 59 PPTA PF01239.17 GAK63923.1 - 5.6e-40 133.0 17.6 7.3e-09 34.5 1.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.1 GAK63923.1 - 0.0052 17.0 0.8 0.037 14.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3366 PF11846.3 GAK63923.1 - 0.069 13.0 3.1 0.057 13.2 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) CDP-OH_P_transf PF01066.16 GAK63924.1 - 5.2e-17 62.0 4.2 5.2e-17 62.0 2.9 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Polysacc_synt_3 PF13440.1 GAK63924.1 - 0.72 9.2 8.6 0.25 10.7 3.6 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein ERO1 PF04137.10 GAK63925.1 - 1.8e-127 425.2 0.0 2.3e-127 424.9 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fer4_18 PF13746.1 GAK63925.1 - 0.032 14.6 0.3 0.13 12.7 0.2 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF3844 PF12955.2 GAK63927.1 - 8.5e-30 102.9 2.0 1.3e-29 102.2 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Peptidase_M17 PF00883.16 GAK63927.1 - 0.02 13.7 0.1 0.096 11.5 0.2 1.9 2 0 0 2 2 2 0 Cytosol aminopeptidase family, catalytic domain Pkinase PF00069.20 GAK63928.1 - 4.2e-39 134.2 0.0 2e-27 95.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63928.1 - 8.6e-24 83.9 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK63928.1 - 0.0024 16.8 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-HIT PF04438.11 GAK63929.1 - 2e-08 33.7 9.5 2.9e-08 33.2 6.6 1.3 1 0 0 1 1 1 1 HIT zinc finger DEAD PF00270.24 GAK63930.1 - 1.7e-45 154.5 0.0 2.9e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK63930.1 - 3.3e-27 94.1 0.0 8.3e-27 92.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BSP_II PF05432.6 GAK63930.1 - 0.0022 17.3 8.5 0.0034 16.6 5.9 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) ResIII PF04851.10 GAK63930.1 - 0.0038 17.0 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Nop14 PF04147.7 GAK63930.1 - 0.23 9.3 10.6 0.39 8.5 7.3 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAK63930.1 - 0.33 9.3 13.4 0.46 8.9 9.3 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 GAK63930.1 - 1.1 7.7 3.4 1.7 7.1 2.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ORC6 PF05460.8 GAK63930.1 - 2.4 7.1 8.7 3.7 6.5 6.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sigma70_ner PF04546.8 GAK63930.1 - 5 6.6 10.0 13 5.2 6.9 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region SWIRM PF04433.12 GAK63931.1 - 1.4e-15 57.1 0.0 3.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 GAK63931.1 - 1.8e-10 40.6 0.0 4.6e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 GAK63931.1 - 4.2e-09 35.8 6.6 7.4e-09 35.0 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 GAK63931.1 - 4.3e-07 29.9 0.0 1.3e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spore_coat_CotO PF14153.1 GAK63931.1 - 0.81 9.0 9.5 2.4 7.5 6.6 1.8 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 GAK63931.1 - 1.1 8.9 9.1 0.057 13.2 1.9 2.0 2 0 0 2 2 2 0 DDHD domain Ycf1 PF05758.7 GAK63931.1 - 1.9 6.0 7.8 2.7 5.6 5.4 1.1 1 0 0 1 1 1 0 Ycf1 Ras PF00071.17 GAK63932.1 - 3.5e-53 179.3 0.0 4.5e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK63932.1 - 8.6e-16 58.5 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK63932.1 - 3.4e-10 39.4 0.0 7e-10 38.4 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK63932.1 - 6.2e-05 22.9 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK63932.1 - 0.0016 17.9 0.0 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAK63932.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 GAK63932.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 GAK63932.1 - 0.19 10.8 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Methyltransf_16 PF10294.4 GAK63933.1 - 4.5e-39 133.6 0.0 7.8e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAK63933.1 - 6.6e-05 23.4 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK63933.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAK63933.1 - 0.0068 16.4 0.1 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain B12D PF06522.6 GAK63934.1 - 2.2e-05 24.0 0.0 9.6e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DASH_Dam1 PF08653.5 GAK63935.1 - 7.4e-24 83.2 0.4 1.2e-23 82.6 0.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Mucin PF01456.12 GAK63935.1 - 0.013 15.2 18.2 0.013 15.2 12.6 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein HTH_9 PF08221.6 GAK63935.1 - 0.1 12.4 0.1 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RPA_C PF08784.6 GAK63935.1 - 0.59 10.5 2.8 1.8 9.0 0.1 2.8 2 1 0 2 2 2 0 Replication protein A C terminal DUF3439 PF11921.3 GAK63935.1 - 0.84 9.3 19.0 2.1 8.1 13.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 GAK63935.1 - 1.1 8.9 14.1 0.28 10.8 6.8 2.0 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.7 GAK63935.1 - 2.8 5.5 6.2 3.9 5.1 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 GAK63935.1 - 4.9 6.2 23.3 0.64 9.1 1.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GF_recep_IV PF14843.1 GAK63936.1 - 0.074 12.6 0.3 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Growth factor receptor domain IV EBP PF05241.7 GAK63937.1 - 2e-57 193.3 11.4 3.6e-57 192.5 7.9 1.4 1 0 0 1 1 1 1 Emopamil binding protein Glycos_transf_1 PF00534.15 GAK63937.1 - 2.4e-14 53.0 0.0 3.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAK63937.1 - 5.1e-06 26.3 0.2 1.9e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 GAK63937.1 - 5.2e-06 26.6 0.0 4.5e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAK63937.1 - 0.00025 21.1 5.2 0.00025 21.1 3.6 2.9 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain 7tm_1 PF00001.16 GAK63937.1 - 0.0058 15.8 0.2 0.17 11.0 0.1 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DNA_mis_repair PF01119.14 GAK63938.1 - 3.9e-31 106.9 0.0 6.6e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAK63938.1 - 1.3e-11 44.2 0.0 3.3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAK63938.1 - 4e-10 39.3 0.0 3.3e-09 36.4 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CBFD_NFYB_HMF PF00808.18 GAK63939.1 - 5.5e-14 51.9 0.2 8.4e-14 51.3 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAK63939.1 - 5.3e-06 26.4 0.3 8.3e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DNA_pol3_alpha PF07733.7 GAK63939.1 - 0.045 12.1 0.6 0.059 11.8 0.4 1.1 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit Cwf_Cwc_15 PF04889.7 GAK63939.1 - 0.23 11.1 10.8 0.28 10.8 7.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.6 GAK63939.1 - 0.65 9.8 10.0 0.081 12.7 4.1 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RhoGEF PF00621.15 GAK63940.1 - 2.8e-16 59.9 0.0 5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Menin PF05053.8 GAK63940.1 - 2 6.5 3.1 3.4 5.7 2.2 1.3 1 0 0 1 1 1 0 Menin Zn_clus PF00172.13 GAK63941.1 - 0.0015 18.3 7.6 0.0036 17.1 5.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Poly_export PF02563.11 GAK63942.1 - 0.043 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein Asp PF00026.18 GAK63944.1 - 6.7e-36 124.1 0.0 5.4e-35 121.1 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAK63944.1 - 6.2e-05 23.0 0.1 0.00017 21.5 0.1 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAK63944.1 - 0.028 14.9 1.0 35 5.0 0.0 3.6 2 1 0 2 2 2 0 Aspartyl protease Oxysterol_BP PF01237.13 GAK63945.1 - 3.3e-124 413.9 0.0 5.8e-124 413.1 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Put_Phosphatase PF06888.7 GAK63945.1 - 2.1e-51 174.3 0.0 3.7e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Putative Phosphatase Ank PF00023.25 GAK63945.1 - 8.8e-19 66.3 0.5 6e-06 25.8 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 GAK63945.1 - 9.6e-18 64.3 3.6 5.2e-13 49.1 0.3 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAK63945.1 - 3.5e-17 62.0 2.2 4.1e-07 30.0 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK63945.1 - 2.9e-15 54.8 0.3 0.00013 21.8 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAK63945.1 - 8.2e-10 38.9 3.0 5.3e-05 23.6 0.2 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PH PF00169.24 GAK63945.1 - 4.1e-09 36.5 0.0 8.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAK63945.1 - 3.5e-08 33.6 0.2 9.9e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain HAD_2 PF13419.1 GAK63945.1 - 3.1e-07 30.7 1.8 1.4e-06 28.6 0.0 2.8 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase PH_8 PF15409.1 GAK63945.1 - 2.6e-06 27.3 0.1 7.6e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Zn_clus PF00172.13 GAK63946.1 - 0.21 11.4 8.3 1.3 8.9 0.6 2.7 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4583 PF15190.1 GAK63947.1 - 0.039 13.5 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) Ribonuclease PF00545.15 GAK63948.1 - 6.4e-10 38.9 0.6 4.7e-08 32.9 0.0 2.5 1 1 1 2 2 2 2 ribonuclease Tad PF13400.1 GAK63949.1 - 3.2 7.8 7.4 0.43 10.6 0.6 2.8 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like ERCC4 PF02732.10 GAK63950.1 - 3.8e-14 52.6 0.0 6.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain zf-PARP PF00645.13 GAK63951.1 - 5.2e-21 74.6 0.0 7.4e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.14 GAK63951.1 - 4.2e-19 65.7 110.5 0.063 12.9 0.6 11.5 11 0 0 11 11 11 11 AT hook motif Peptidase_C97 PF05903.9 GAK63952.1 - 9.7e-21 74.1 0.0 8.5e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 PPPDE putative peptidase domain LRAT PF04970.8 GAK63952.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase GNAT_acetyltr_2 PF13718.1 GAK63953.1 - 3.3e-75 251.7 0.0 5.6e-75 250.9 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 GAK63953.1 - 6.7e-65 218.0 0.0 1.2e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 GAK63953.1 - 1.2e-32 111.4 0.0 3e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 GAK63953.1 - 5.7e-28 96.9 0.9 1.6e-27 95.5 0.2 2.2 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 GAK63953.1 - 0.0013 18.7 0.0 0.0049 16.8 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK63953.1 - 0.0018 18.3 0.0 0.031 14.4 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Methyltransf_7 PF03492.10 GAK63955.1 - 4.8e-06 25.5 0.1 0.017 13.8 0.3 2.7 2 1 1 3 3 3 2 SAM dependent carboxyl methyltransferase DUF3670 PF12419.3 GAK63955.1 - 0.017 14.5 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 SNF2 Helicase protein WhiA_N PF10298.4 GAK63955.1 - 0.22 11.4 0.4 0.66 9.8 0.0 1.9 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain cNMP_binding PF00027.24 GAK63956.1 - 6.2e-37 125.2 0.0 1.6e-16 59.8 0.0 5.7 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Glycos_transf_2 PF00535.21 GAK63956.1 - 1.7e-20 73.4 0.0 3.8e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Patatin PF01734.17 GAK63956.1 - 2.6e-16 60.1 7.2 2.5e-15 56.9 3.2 3.4 2 1 0 2 2 2 1 Patatin-like phospholipase Glyco_tranf_2_3 PF13641.1 GAK63956.1 - 8.8e-08 32.2 3.3 7.5e-07 29.1 0.2 2.8 2 1 1 3 3 3 1 Glycosyltransferase like family 2 Peptidase_C1_2 PF03051.10 GAK63957.1 - 9e-143 475.9 0.0 2.7e-142 474.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 GAK63957.1 - 0.0004 20.3 0.8 0.52 10.1 0.0 2.7 2 1 0 2 2 2 2 Papain family cysteine protease 2-Hacid_dh_C PF02826.14 GAK63958.1 - 1.6e-52 177.2 0.0 3.2e-52 176.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAK63958.1 - 2.5e-32 111.1 0.0 3.7e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAK63958.1 - 0.00058 19.7 0.1 0.0015 18.3 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 GAK63958.1 - 0.0013 18.6 0.6 0.003 17.4 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 GAK63958.1 - 5.6 6.5 6.6 3.4 7.2 0.2 2.9 3 1 1 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SRP-alpha_N PF04086.8 GAK63963.1 - 5.4e-66 222.8 2.7 8.3e-66 222.2 1.9 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 GAK63963.1 - 2.1e-46 157.8 0.1 1.1e-45 155.5 0.1 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 GAK63963.1 - 3.3e-07 30.3 0.0 1.2e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 GAK63963.1 - 1.5e-05 24.5 0.1 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 GAK63963.1 - 5.4e-05 22.0 0.0 0.00016 20.5 0.0 1.7 1 1 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 GAK63963.1 - 0.0014 18.6 1.1 0.017 15.1 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAK63963.1 - 0.0037 17.3 0.0 0.029 14.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 GAK63963.1 - 0.026 14.2 0.0 0.077 12.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 GAK63963.1 - 0.045 13.2 0.4 0.21 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA-like domain Fer4_NifH PF00142.13 GAK63963.1 - 0.051 12.7 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Nucleoplasmin PF03066.10 GAK63963.1 - 0.095 12.2 6.8 0.17 11.3 4.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin ETF PF01012.16 GAK63963.1 - 0.13 11.9 2.6 0.24 11.0 0.1 2.5 2 1 1 3 3 3 0 Electron transfer flavoprotein domain Sigma70_ner PF04546.8 GAK63963.1 - 1.2 8.7 10.8 0.034 13.7 2.0 2.3 2 1 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 GAK63963.1 - 6.6 7.0 12.3 14 5.9 8.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ATP_bind_1 PF03029.12 GAK63964.1 - 2.7e-82 275.9 0.0 3.1e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAK63964.1 - 2.7e-07 31.4 0.1 5.6e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 GAK63964.1 - 4.5e-06 26.1 0.0 1.1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 GAK63964.1 - 0.00017 21.5 0.2 0.0042 17.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAK63964.1 - 0.00054 19.4 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 GAK63964.1 - 0.00071 18.4 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein T2SE PF00437.15 GAK63964.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 GAK63964.1 - 0.0012 18.9 0.0 0.0043 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAK63964.1 - 0.0012 19.1 0.0 0.0031 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAK63964.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain GTP_EFTU PF00009.22 GAK63964.1 - 0.0017 17.8 0.0 0.4 10.0 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 GAK63964.1 - 0.002 17.6 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 GAK63964.1 - 0.003 17.2 0.0 0.0076 15.9 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAK63964.1 - 0.003 17.7 0.0 0.041 14.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAK63964.1 - 0.0038 16.8 0.0 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAK63964.1 - 0.0045 16.8 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAK63964.1 - 0.0054 16.6 0.0 0.026 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAK63964.1 - 0.0072 15.7 1.2 0.055 12.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 GAK63964.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain MMR_HSR1 PF01926.18 GAK63964.1 - 0.0082 16.0 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 GAK63964.1 - 0.015 15.5 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 GAK63964.1 - 0.037 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAK63964.1 - 0.039 13.0 0.0 0.058 12.4 0.0 1.5 1 1 0 1 1 1 0 KaiC IstB_IS21 PF01695.12 GAK63964.1 - 0.041 13.3 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 GAK63964.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NTPase CobU PF02283.11 GAK63964.1 - 0.075 12.4 0.1 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NACHT PF05729.7 GAK63964.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 GAK63964.1 - 0.086 13.1 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Gtr1_RagA PF04670.7 GAK63964.1 - 0.1 11.7 0.1 4 6.5 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SRP54 PF00448.17 GAK63964.1 - 0.11 11.9 0.0 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MipZ PF09140.6 GAK63964.1 - 0.15 11.1 0.0 1.5 7.8 0.0 2.2 1 1 0 1 1 1 0 ATPase MipZ Zeta_toxin PF06414.7 GAK63964.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin zf-RING_2 PF13639.1 GAK63965.1 - 8.9e-14 51.0 4.0 1.4e-13 50.3 2.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 GAK63965.1 - 7.5e-09 35.2 0.1 5.3e-08 32.4 0.1 2.2 1 1 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 GAK63965.1 - 3.7e-07 30.0 4.2 6e-07 29.3 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK63965.1 - 3.1e-06 26.8 1.8 4.8e-06 26.2 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 GAK63965.1 - 3.8e-06 26.9 0.8 6.8e-06 26.1 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAK63965.1 - 2e-05 24.1 2.2 3e-05 23.5 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK63965.1 - 0.00035 20.1 1.3 0.00054 19.5 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAK63965.1 - 0.039 13.7 1.0 0.086 12.6 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 GAK63965.1 - 0.087 12.7 3.1 0.48 10.4 2.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 GAK63965.1 - 0.95 9.2 5.8 0.4 10.4 0.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Iso_dh PF00180.15 GAK63966.1 - 9.6e-116 386.5 0.0 1.1e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Cullin_binding PF03556.10 GAK63967.1 - 9.5e-34 116.0 1.5 1.7e-33 115.2 1.0 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 GAK63967.1 - 3.4e-07 29.6 0.1 7.4e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain TipAS PF07739.8 GAK63967.1 - 0.76 10.1 4.3 0.78 10.0 0.7 2.6 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Metal_resist PF13801.1 GAK63967.1 - 6.3 6.7 13.7 0.85 9.6 4.6 2.5 2 1 0 2 2 2 0 Heavy-metal resistance Ribosomal_L5_C PF00673.16 GAK63968.1 - 4.9e-06 26.1 0.0 1.6e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 GAK63968.1 - 0.0015 18.2 0.6 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 GAK63969.1 - 4.3e-18 64.6 1.0 5.7e-18 64.2 0.7 1.2 1 0 0 1 1 1 1 LSM domain MRJP PF03022.11 GAK63969.1 - 0.079 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Major royal jelly protein DUF1541 PF07563.6 GAK63969.1 - 0.13 11.9 0.1 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Aldedh PF00171.17 GAK63970.1 - 4.2e-108 361.6 0.0 5.2e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NOG1 PF06858.9 GAK63972.1 - 3.4e-28 97.2 0.1 6.3e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 GAK63972.1 - 1.3e-27 95.1 3.4 3.5e-27 93.8 2.4 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 GAK63972.1 - 9.7e-18 64.2 0.0 2.4e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK63972.1 - 4.1e-08 32.6 0.0 8.4e-08 31.6 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 GAK63972.1 - 0.00039 20.9 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 GAK63972.1 - 0.0084 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 GAK63972.1 - 0.011 14.9 0.0 0.1 11.7 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAK63972.1 - 0.046 13.5 0.9 2.3 7.9 0.0 3.1 2 1 1 3 3 3 0 Dynamin family Mito_carr PF00153.22 GAK63973.1 - 6.1e-55 182.9 8.2 2.7e-18 65.4 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TRAP-gamma PF07074.7 GAK63974.1 - 0.11 12.0 0.7 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) BAP PF06639.6 GAK63974.1 - 0.12 12.0 1.7 0.16 11.6 0.3 1.8 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) Glyoxalase_2 PF12681.2 GAK63976.1 - 3.4e-08 34.0 0.0 9.6e-07 29.3 0.0 2.6 1 1 0 1 1 1 1 Glyoxalase-like domain Cauli_VI PF01693.11 GAK63976.1 - 8.6e-05 22.4 0.1 0.00015 21.7 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Glyoxalase PF00903.20 GAK63976.1 - 0.00093 19.1 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sec16 PF12932.2 GAK63976.1 - 0.016 15.1 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region WD40 PF00400.27 GAK63978.1 - 1.7e-53 176.6 22.1 1.5e-10 40.5 0.5 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAK63978.1 - 4.9e-05 21.7 0.1 8.3e-05 21.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 GAK63978.1 - 0.025 14.8 4.4 10 6.5 0.3 4.5 4 0 0 4 4 4 0 PQQ-like domain DUF3312 PF11768.3 GAK63978.1 - 0.063 11.4 0.0 0.48 8.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Nup160 PF11715.3 GAK63978.1 - 0.087 10.9 2.2 5.3 5.0 0.2 2.8 1 1 0 2 2 2 0 Nucleoporin Nup120/160 GTP_EFTU PF00009.22 GAK63979.1 - 1.4e-50 171.3 0.1 3.1e-50 170.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 GAK63979.1 - 8.7e-14 51.1 0.0 2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 GAK63979.1 - 6.3e-09 35.5 0.0 2.2e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 GAK63979.1 - 1.6e-05 24.4 0.0 0.00062 19.3 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 GAK63979.1 - 2.5e-05 24.2 0.0 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 GAK63979.1 - 0.0027 17.7 0.0 0.01 15.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 GAK63979.1 - 0.13 12.0 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family DDHD PF02862.12 GAK63979.1 - 1.4 8.6 4.4 3.9 7.1 1.7 2.3 2 0 0 2 2 2 0 DDHD domain ADH_zinc_N_2 PF13602.1 GAK63982.1 - 8.8e-09 36.3 0.0 3.3e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK63982.1 - 2.8e-06 27.0 0.3 6.3e-06 25.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK63982.1 - 0.034 13.7 0.0 0.09 12.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_1 PF00076.17 GAK63983.1 - 4e-16 58.4 0.0 8.2e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK63983.1 - 1.3e-09 37.8 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK63983.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.6 GAK63984.1 - 4.2e-25 87.4 0.0 1.9e-24 85.3 0.0 2.1 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.8 GAK63984.1 - 0.075 12.3 0.0 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain FliT PF05400.8 GAK63984.1 - 0.42 11.0 9.5 0.92 9.9 0.4 3.7 3 0 0 3 3 3 0 Flagellar protein FliT HEAT_2 PF13646.1 GAK63984.1 - 0.66 10.2 17.4 0.033 14.4 1.8 4.4 3 3 0 3 3 3 0 HEAT repeats Abhydrolase_5 PF12695.2 GAK63985.1 - 2.3e-07 30.6 0.0 6.2e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK63985.1 - 1.5e-05 25.0 2.7 3e-05 24.0 1.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAK63985.1 - 0.00086 18.9 0.1 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 GAK63985.1 - 0.0074 15.5 0.2 0.75 9.0 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAK63985.1 - 0.017 14.7 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 GAK63985.1 - 0.032 14.4 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Cofilin_ADF PF00241.15 GAK63987.1 - 5.1e-11 42.5 0.0 5.5e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ox_reductase_C PF08635.5 GAK63988.1 - 4.9e-77 256.1 0.1 7.2e-77 255.6 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 GAK63988.1 - 4.4e-26 91.7 0.0 7.4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAK63988.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain RRM_1 PF00076.17 GAK63989.1 - 1.8e-23 81.9 0.0 2.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK63989.1 - 2.1e-18 66.0 0.0 2.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK63989.1 - 8.6e-11 41.5 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytadhesin_P30 PF07271.6 GAK63989.1 - 0.11 11.7 7.6 0.14 11.4 5.2 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 RPA_interact_C PF14768.1 GAK63990.1 - 0.029 14.7 0.2 0.046 14.1 0.1 1.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal OTU PF02338.14 GAK63991.1 - 1.2e-14 54.9 0.0 3.3e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Caprin-1_C PF12287.3 GAK63992.1 - 0.03 13.7 0.7 1.3 8.3 0.1 2.0 1 1 1 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term Pkinase PF00069.20 GAK63993.1 - 2.8e-45 154.4 0.0 1.1e-44 152.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK63993.1 - 1e-24 87.0 0.0 2.3e-24 85.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK63993.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Metallothio_11 PF02066.10 GAK63994.1 - 0.78 9.6 4.9 0.16 11.8 0.8 1.8 2 0 0 2 2 2 0 Metallothionein family 11 Glyco_transf_20 PF00982.16 GAK63996.1 - 2.7e-153 510.8 0.0 3.6e-153 510.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAK63996.1 - 3.3e-20 71.9 0.0 6.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase OPA3 PF07047.7 GAK63997.1 - 1.3e-31 109.1 0.6 2.7e-31 108.1 0.4 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF883 PF05957.8 GAK63998.1 - 0.036 14.4 3.4 0.097 13.0 2.4 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 GAK63998.1 - 0.048 13.6 1.3 0.097 12.6 0.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HSCB_C PF07743.8 GAK63998.1 - 2.9 8.4 4.7 21 5.6 0.9 2.6 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain NUDIX_2 PF13869.1 GAK63999.1 - 6.3e-43 146.2 0.0 8.6e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Cas_Csy1 PF09611.5 GAK63999.1 - 0.034 13.0 0.4 0.047 12.6 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) TBP PF00352.16 GAK64000.1 - 3.3e-67 221.8 0.2 6.9e-33 111.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 GAK64000.1 - 9.1e-05 22.4 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Ferric_reduct PF01794.14 GAK64001.1 - 3.5e-20 72.3 5.1 3.5e-20 72.3 3.6 3.2 3 1 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAK64001.1 - 6.3e-16 58.1 0.0 1.5e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAK64001.1 - 6e-15 55.4 0.0 1.8e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 GAK64001.1 - 4.9e-05 23.8 0.0 0.53 10.8 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain adh_short PF00106.20 GAK64002.1 - 6.4e-22 78.2 0.3 8.4e-22 77.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK64002.1 - 2.5e-13 50.3 0.0 3.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK64002.1 - 4.1e-05 23.3 0.1 6.6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF562 PF04763.7 GAK64002.1 - 0.0061 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF562) DUF1776 PF08643.5 GAK64002.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 GAK64002.1 - 0.11 12.1 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bap31 PF05529.7 GAK64003.1 - 5.6e-57 192.3 4.4 7.9e-57 191.8 3.1 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF4446 PF14584.1 GAK64003.1 - 0.0052 16.6 1.8 0.0079 16.0 0.3 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF4446) DUF4407 PF14362.1 GAK64003.1 - 0.14 11.0 1.7 0.18 10.7 1.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SE PF08491.5 GAK64005.1 - 1.1e-98 329.4 0.0 2e-98 328.5 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 GAK64005.1 - 1.9e-11 43.6 0.0 4.4e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAK64005.1 - 4.5e-11 42.2 0.2 4.4e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK64005.1 - 9e-05 22.4 0.3 0.00023 21.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK64005.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK64005.1 - 0.00058 19.0 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAK64005.1 - 0.00097 18.0 0.4 0.025 13.4 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 GAK64005.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 GAK64005.1 - 0.0031 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 GAK64005.1 - 0.0075 15.1 0.0 0.018 13.9 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 GAK64005.1 - 0.023 15.0 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAK64005.1 - 0.029 14.0 0.1 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 GAK64005.1 - 0.061 12.2 0.1 0.72 8.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 GAK64005.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 GAK64005.1 - 0.17 10.3 0.0 0.42 9.0 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 GAK64005.1 - 0.21 11.6 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Oxidored_molyb PF00174.14 GAK64006.1 - 5.4e-41 139.8 0.0 7.7e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAK64006.1 - 9.1e-16 57.6 1.5 3.8e-09 36.2 0.8 2.4 2 0 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain Bromo_TP PF07524.8 GAK64007.1 - 3.6e-12 45.8 0.1 1.3e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 GAK64007.1 - 0.013 15.5 0.0 0.037 14.0 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAK64007.1 - 0.013 15.5 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAK64007.1 - 0.019 15.1 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S RRM_1 PF00076.17 GAK64008.1 - 1.9e-17 62.6 0.0 3.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64008.1 - 3.7e-13 49.2 0.0 7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64008.1 - 1.8e-07 30.8 0.0 3.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tup_N PF08581.5 GAK64008.1 - 0.13 12.5 1.9 0.33 11.1 0.3 2.0 1 1 1 2 2 2 0 Tup N-terminal Complex1_LYR_1 PF13232.1 GAK64009.1 - 1.1e-16 60.7 0.3 1.5e-16 60.2 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAK64009.1 - 3.9e-09 36.1 7.8 2.2e-08 33.7 4.1 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 GAK64009.1 - 0.064 13.7 0.0 0.088 13.2 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like tRNA_int_endo PF01974.12 GAK64010.1 - 2.5e-21 75.2 0.0 5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 GAK64010.1 - 6.1e-06 25.7 0.0 0.00018 20.9 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain WD40 PF00400.27 GAK64011.1 - 9e-25 85.6 8.8 2e-06 27.4 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 GAK64011.1 - 4.9e-05 23.1 0.4 0.043 13.5 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 GAK64011.1 - 0.00064 19.3 0.5 0.37 10.5 0.1 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 GAK64011.1 - 0.0017 17.8 0.0 0.67 9.5 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MT-A70 PF05063.9 GAK64012.1 - 2.4e-42 144.4 0.0 3.2e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Pkinase PF00069.20 GAK64013.1 - 3e-74 249.4 0.1 3e-74 249.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64013.1 - 9.4e-53 178.9 2.2 1.1e-52 178.6 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 GAK64013.1 - 6.2e-21 74.5 0.0 2.2e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 GAK64013.1 - 1.2e-09 38.3 1.2 2.4e-09 37.3 0.9 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 GAK64013.1 - 7.2e-07 28.4 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 GAK64013.1 - 0.0003 21.0 0.8 0.022 15.0 0.2 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain APH PF01636.18 GAK64013.1 - 0.003 17.3 0.0 0.0098 15.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Vps35 PF03635.12 GAK64015.1 - 0 1146.8 0.0 0 1146.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Totivirus_coat PF05518.6 GAK64015.1 - 0.25 9.1 16.0 0.43 8.3 11.1 1.4 1 0 0 1 1 1 0 Totivirus coat protein Nop14 PF04147.7 GAK64015.1 - 1.8 6.3 3.2 3.3 5.5 2.2 1.3 1 0 0 1 1 1 0 Nop14-like family zf-primase PF09329.6 GAK64016.1 - 3.3e-14 52.1 1.8 7.1e-14 51.1 1.2 1.6 1 0 0 1 1 1 1 Primase zinc finger 2OG-FeII_Oxy_2 PF13532.1 GAK64018.1 - 1.7e-14 54.1 0.0 4.1e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAK64018.1 - 0.0001 22.5 0.1 0.087 13.1 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Antimicrobial14 PF08109.6 GAK64018.1 - 0.12 12.2 0.1 9 6.2 0.0 2.5 2 0 0 2 2 2 0 Lactocin 705 family RINGv PF12906.2 GAK64019.1 - 4.6e-07 29.7 6.7 8.8e-07 28.8 4.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 GAK64019.1 - 0.0021 18.1 4.0 0.0034 17.4 2.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAK64019.1 - 0.016 15.0 9.0 0.041 13.7 6.2 1.7 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 GAK64019.1 - 0.044 13.3 1.3 0.086 12.4 0.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tmpp129 PF10272.4 GAK64019.1 - 0.3 9.7 3.8 0.46 9.1 2.6 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C3HC4 PF00097.20 GAK64019.1 - 1.1 9.0 4.4 1.8 8.3 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK64019.1 - 1.3 8.7 7.4 4.7 6.9 5.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SRP9-21 PF05486.7 GAK64020.1 - 5.5e-19 67.6 0.4 9.6e-19 66.9 0.3 1.4 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Rrn6 PF10214.4 GAK64020.1 - 0.26 9.3 2.9 0.33 8.9 2.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1180 PF06679.7 GAK64020.1 - 7.9 6.3 7.0 14 5.4 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mito_carr PF00153.22 GAK64021.1 - 9e-66 217.6 5.2 3.6e-23 81.0 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HMG_box PF00505.14 GAK64022.1 - 2.1e-23 82.3 1.2 3.4e-23 81.6 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAK64022.1 - 1.2e-18 67.2 1.7 3e-18 65.9 1.2 1.7 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 GAK64022.1 - 0.036 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain PS_Dcarbxylase PF02666.10 GAK64023.1 - 9e-46 155.7 0.0 1.2e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Dehydratase_LU PF02286.10 GAK64023.1 - 0.2 9.8 0.0 0.29 9.3 0.0 1.1 1 0 0 1 1 1 0 Dehydratase large subunit AAA_12 PF13087.1 GAK64024.1 - 3.8e-55 186.3 0.0 5.9e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAK64024.1 - 7.5e-48 163.1 0.2 1.6e-47 162.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAK64024.1 - 8e-12 45.1 0.4 6.8e-09 35.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 GAK64024.1 - 1.7e-11 43.7 0.3 6.1e-11 41.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 GAK64024.1 - 0.00038 20.0 0.0 8.6 5.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 GAK64024.1 - 0.004 16.5 0.2 0.015 14.5 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 GAK64024.1 - 0.0087 15.3 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 GAK64024.1 - 0.018 15.0 2.5 1.6 8.6 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain IATP PF04568.7 GAK64025.1 - 6.2e-18 64.6 2.0 7.1e-18 64.4 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Rabaptin PF03528.10 GAK64025.1 - 4.6e-05 23.2 1.9 4.6e-05 23.2 1.3 1.1 1 0 0 1 1 1 1 Rabaptin UPF0449 PF15136.1 GAK64025.1 - 0.0031 17.6 1.4 0.0037 17.4 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 DUF1366 PF07104.6 GAK64025.1 - 0.0039 16.7 5.4 0.0057 16.2 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1366) DUF2968 PF11180.3 GAK64025.1 - 0.0091 15.3 4.0 0.009 15.4 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF16 PF01519.11 GAK64025.1 - 0.0099 16.0 1.7 0.0099 16.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF16 IncA PF04156.9 GAK64025.1 - 0.014 15.0 1.7 0.012 15.1 1.2 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 GAK64025.1 - 0.017 14.0 2.4 0.015 14.2 1.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HemX PF04375.9 GAK64025.1 - 0.02 13.4 3.7 0.022 13.3 2.5 1.0 1 0 0 1 1 1 0 HemX MOFRL PF05161.8 GAK64025.1 - 0.02 14.9 0.1 0.025 14.6 0.1 1.2 1 1 0 1 1 1 0 MOFRL family AAA_23 PF13476.1 GAK64025.1 - 0.033 14.4 2.3 0.03 14.6 1.6 1.1 1 0 0 1 1 1 0 AAA domain OSTbeta PF15048.1 GAK64025.1 - 0.055 13.5 1.2 0.052 13.6 0.8 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2730 PF10805.3 GAK64025.1 - 0.093 12.4 1.8 0.14 11.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4140 PF13600.1 GAK64025.1 - 0.15 12.5 5.2 0.21 12.0 3.6 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) NinG PF05766.7 GAK64025.1 - 0.39 10.4 4.8 0.47 10.1 3.4 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Vps5 PF09325.5 GAK64025.1 - 0.88 8.7 9.3 1.1 8.4 6.4 1.1 1 0 0 1 1 1 0 Vps5 C terminal like PspB PF06667.7 GAK64025.1 - 3.4 7.6 5.3 4.8 7.1 3.7 1.2 1 0 0 1 1 1 0 Phage shock protein B Bap31 PF05529.7 GAK64025.1 - 5.4 6.4 7.9 6.4 6.1 5.4 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4407 PF14362.1 GAK64025.1 - 9.8 5.0 7.9 12 4.7 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP_sub_h PF10775.4 GAK64026.1 - 1.1e-23 82.6 1.9 1.7e-23 82.0 1.3 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 GAK64026.1 - 0.018 14.9 0.1 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 eIF2_C PF09173.6 GAK64027.1 - 4.2e-38 129.2 0.1 1.1e-37 127.8 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 GAK64027.1 - 3.1e-37 127.8 0.0 5.4e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 GAK64027.1 - 2.6e-13 49.8 2.1 3.7e-13 49.3 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAK64027.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAK64027.1 - 0.07 12.9 0.3 0.21 11.3 0.2 2.1 1 1 0 1 1 1 0 Dynamin family muHD PF10291.4 GAK64028.1 - 1.9e-53 181.2 0.0 2.8e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 GAK64028.1 - 1.5e-10 41.1 0.0 1.5e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2335 PF10097.4 GAK64028.1 - 0.081 12.5 0.9 6 6.5 0.0 3.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) OGFr_III PF04680.8 GAK64028.1 - 2.5 8.3 11.9 8.6 6.6 3.2 3.5 3 0 0 3 3 3 0 Opioid growth factor receptor repeat Pkinase PF00069.20 GAK64029.1 - 6.7e-73 245.0 0.0 8.2e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64029.1 - 6.6e-32 110.6 0.0 8.4e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAK64029.1 - 0.00014 20.9 0.0 0.0005 19.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAK64029.1 - 0.00048 19.9 0.0 0.00098 18.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAK64029.1 - 0.002 17.1 0.0 0.015 14.2 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 GAK64029.1 - 0.017 14.4 0.0 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Glyco_hydro_35 PF01301.14 GAK64030.1 - 5.7e-72 242.7 0.0 8.2e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 GAK64030.1 - 1.8e-39 134.4 4.0 4.1e-21 75.3 0.2 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 GAK64030.1 - 1.6e-10 40.6 0.0 4.5e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 Cellulase PF00150.13 GAK64030.1 - 3.1e-05 23.3 0.0 0.00046 19.4 0.0 2.6 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) LSM PF01423.17 GAK64031.1 - 2.6e-17 62.1 0.2 3.2e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain DNA_repr_REX1B PF14966.1 GAK64032.1 - 1.4e-09 38.2 2.8 0.00064 20.0 0.6 2.9 3 0 0 3 3 3 2 DNA repair REX1-B LEH PF07858.7 GAK64032.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain DUF3618 PF12277.3 GAK64032.1 - 0.25 11.3 3.4 0.86 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) COMP PF11598.3 GAK64032.1 - 1.8 8.7 4.2 1.5 8.9 1.5 2.0 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein FliT PF05400.8 GAK64032.1 - 1.9 8.9 10.3 4.2 7.8 1.8 2.4 1 1 1 2 2 2 0 Flagellar protein FliT Ribosomal_S4 PF00163.14 GAK64033.1 - 4.6e-27 94.2 0.8 1e-26 93.1 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 GAK64033.1 - 4.5e-11 42.0 4.2 5.5e-11 41.7 0.6 2.7 2 0 0 2 2 2 1 S4 domain Ribosomal_L21e PF01157.13 GAK64034.1 - 3.7e-35 119.6 4.3 5.3e-35 119.1 2.7 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3708 PF12501.3 GAK64034.1 - 0.1 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Mito_carr PF00153.22 GAK64035.1 - 7.7e-73 240.2 11.1 1.8e-25 88.4 0.0 4.7 5 0 0 5 5 5 4 Mitochondrial carrier protein Cpn60_TCP1 PF00118.19 GAK64036.1 - 1.5e-149 498.7 2.3 1.7e-149 498.5 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF89 PF01937.14 GAK64037.1 - 1.6e-108 362.7 0.0 1.9e-108 362.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Got1 PF04178.7 GAK64037.1 - 9e-28 96.7 12.7 1.5e-27 96.0 8.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family RRM_1 PF00076.17 GAK64038.1 - 1.1e-73 242.7 3.6 8.8e-19 66.9 0.0 6.1 7 0 0 7 7 7 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64038.1 - 1.1e-68 227.1 0.4 1.5e-18 66.4 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64038.1 - 4.6e-38 128.8 2.8 1.8e-06 27.7 0.0 6.3 7 0 0 7 7 7 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 GAK64038.1 - 0.00039 20.3 0.0 0.93 9.5 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif 2 Limkain-b1 PF11608.3 GAK64038.1 - 0.0072 16.0 0.0 0.19 11.5 0.0 3.5 4 0 0 4 4 4 1 Limkain b1 HTH_CodY PF08222.6 GAK64038.1 - 0.15 11.4 0.1 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain AAA_13 PF13166.1 GAK64039.1 - 0.02 13.4 9.8 0.02 13.3 2.3 2.2 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.6 GAK64039.1 - 0.032 12.8 16.8 0.018 13.7 3.1 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 GAK64039.1 - 0.62 9.4 14.1 4.8 6.5 0.2 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) Atg14 PF10186.4 GAK64039.1 - 3 6.7 19.8 1.7 7.5 3.0 2.8 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 GAK64039.1 - 3.5 7.0 32.8 0.35 10.2 3.6 3.5 2 1 1 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.7 GAK64039.1 - 4.3 7.1 7.3 28 4.5 0.3 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.10 GAK64039.1 - 6 6.8 49.1 0.41 10.6 7.6 3.8 2 1 1 3 3 3 0 Fez1 GTP_EFTU PF00009.22 GAK64040.1 - 3.6e-34 117.8 3.9 2.4e-33 115.1 1.2 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAK64040.1 - 1.5e-23 82.7 1.5 3.3e-23 81.6 1.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 GAK64040.1 - 4.5e-06 26.6 0.1 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK64040.1 - 8.5e-05 21.8 0.1 0.00035 19.8 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D2 PF03144.20 GAK64040.1 - 8.9e-05 22.5 0.2 0.062 13.4 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 SRPRB PF09439.5 GAK64040.1 - 0.015 14.5 1.2 0.025 13.8 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MobB PF03205.9 GAK64040.1 - 0.033 13.8 0.4 0.092 12.4 0.3 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 GAK64040.1 - 0.033 13.6 0.4 3.2 7.2 0.0 3.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3983 PF13137.1 GAK64040.1 - 0.16 11.6 3.1 0.14 11.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) Noc2 PF03715.8 GAK64041.1 - 2.4e-104 348.3 0.5 3.7e-104 347.7 0.4 1.3 1 0 0 1 1 1 1 Noc2p family AAA_25 PF13481.1 GAK64042.1 - 0.0062 15.9 0.0 0.04 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAK64042.1 - 0.032 14.1 0.0 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAK64042.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC RNA12 PF10443.4 GAK64042.1 - 0.19 10.2 0.0 0.34 9.3 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein TFIIF_alpha PF05793.7 GAK64043.1 - 0.89 7.8 3.9 1.7 6.9 2.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UCH PF00443.24 GAK64044.1 - 2.7e-45 154.6 0.0 3.5e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK64044.1 - 1e-21 77.6 0.0 9.7e-21 74.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 GAK64044.1 - 4e-06 26.1 0.0 9.6e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Vfa1 PF08432.5 GAK64044.1 - 2.8 7.9 9.6 6 6.8 6.6 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_S4 PF00163.14 GAK64045.1 - 2.6e-12 46.9 0.6 4.5e-12 46.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 GAK64045.1 - 6.3e-11 41.5 0.0 1.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain Syntaxin_2 PF14523.1 GAK64046.1 - 8.7e-20 70.6 3.3 2.1e-19 69.4 0.8 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 GAK64046.1 - 2.3e-16 59.2 5.3 4.1e-16 58.4 1.1 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 GAK64046.1 - 0.07 13.3 15.1 1.3 9.1 8.9 3.2 1 1 1 2 2 2 0 Syntaxin WD40 PF00400.27 GAK64047.1 - 4.3e-12 45.4 2.3 1.3e-05 24.8 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4112 PF13430.1 GAK64048.1 - 2e-27 95.1 0.0 2.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Tyr_Deacylase PF02580.11 GAK64050.1 - 1.5e-39 135.2 0.0 5.5e-25 88.0 0.0 2.1 2 0 0 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase DUF959 PF06121.9 GAK64050.1 - 0.049 13.2 4.7 0.074 12.6 3.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) SKG6 PF08693.5 GAK64053.1 - 1.5 8.2 3.0 2.7 7.3 2.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase PF00069.20 GAK64054.1 - 6.2e-71 238.5 0.0 8.3e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64054.1 - 9e-29 100.3 0.0 1.9e-28 99.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK64054.1 - 8.7e-05 21.6 0.0 0.00065 18.7 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAK64054.1 - 0.024 13.7 0.2 0.043 12.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAK64054.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CBF PF03914.12 GAK64055.1 - 3.8e-39 133.7 1.5 5.7e-39 133.1 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family RR_TM4-6 PF06459.7 GAK64055.1 - 6.9 6.4 7.9 0.23 11.2 0.6 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TFIID_20kDa PF03847.8 GAK64057.1 - 5.3e-30 103.4 1.4 8.1e-30 102.9 1.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF4615 PF15393.1 GAK64057.1 - 0.0017 18.5 1.5 0.0017 18.5 1.1 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4615) APG5 PF04106.7 GAK64058.1 - 1.7e-45 154.9 0.0 2.9e-45 154.1 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Apg5 Peptidase_M22 PF00814.20 GAK64059.1 - 9.8e-78 261.3 0.1 2.5e-76 256.6 0.0 2.0 1 1 0 1 1 1 1 Glycoprotease family DUF2392 PF10288.4 GAK64060.1 - 2e-19 69.9 0.0 4.3e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Myb_DNA-binding PF00249.26 GAK64061.1 - 4.3e-16 58.6 0.0 4.1e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAK64061.1 - 4.4e-15 55.5 0.0 1.1e-07 31.8 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain MBOAT_2 PF13813.1 GAK64062.1 - 2.3e-14 53.1 3.5 2.3e-14 53.1 2.4 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RNA_pol_L_2 PF13656.1 GAK64063.1 - 2e-26 91.2 0.0 2.7e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAK64063.1 - 2.7e-13 48.8 0.0 3.5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pex14_N PF04695.8 GAK64064.1 - 1e-30 106.5 1.2 1.5e-29 102.7 0.0 3.0 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 GAK64064.1 - 1.6e-05 24.5 2.7 3e-05 23.7 1.9 1.4 1 0 0 1 1 1 1 IncA protein Spc7 PF08317.6 GAK64064.1 - 0.0037 15.9 3.1 0.0079 14.8 2.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3584 PF12128.3 GAK64064.1 - 0.0088 13.4 5.6 0.012 13.0 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3583 PF12126.3 GAK64064.1 - 0.0092 15.0 1.8 0.018 14.1 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) DUF1664 PF07889.7 GAK64064.1 - 0.021 14.6 3.4 0.08 12.7 2.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HALZ PF02183.13 GAK64064.1 - 0.022 14.4 6.9 0.13 11.9 0.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4631 PF15450.1 GAK64064.1 - 0.025 12.9 5.7 0.037 12.3 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) Baculo_PEP_C PF04513.7 GAK64064.1 - 0.028 14.2 0.9 0.047 13.5 0.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 GAK64064.1 - 0.029 12.1 11.0 0.035 11.8 3.3 2.0 1 1 1 2 2 2 0 Myosin tail DUF948 PF06103.6 GAK64064.1 - 0.032 14.1 2.8 1.4 8.8 1.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 GAK64064.1 - 0.048 12.8 1.3 0.1 11.7 0.9 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 GAK64064.1 - 0.081 11.9 6.9 0.13 11.3 4.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 GAK64064.1 - 0.082 11.3 1.4 0.11 10.9 1.0 1.1 1 0 0 1 1 1 0 AAA domain Phage_GPO PF05929.6 GAK64064.1 - 0.09 12.0 1.6 0.14 11.4 1.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_MLP1_2 PF07926.7 GAK64064.1 - 0.12 12.1 9.3 0.23 11.2 2.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 GAK64064.1 - 0.14 11.0 3.8 0.2 10.5 2.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 GAK64064.1 - 0.14 12.4 3.6 0.13 12.6 0.7 2.1 2 0 0 2 2 2 0 Spectrin repeat Mod_r PF07200.8 GAK64064.1 - 0.15 11.9 6.1 0.2 11.5 3.2 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2317 PF10079.4 GAK64064.1 - 0.17 10.4 3.8 0.24 9.9 2.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Laminin_II PF06009.7 GAK64064.1 - 0.19 11.5 5.6 0.5 10.1 3.8 1.7 1 1 0 1 1 1 0 Laminin Domain II Enkurin PF13864.1 GAK64064.1 - 0.2 11.8 3.5 0.16 12.1 0.6 2.0 1 1 1 2 2 2 0 Calmodulin-binding DUF2968 PF11180.3 GAK64064.1 - 0.2 10.9 6.7 0.56 9.5 4.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) EzrA PF06160.7 GAK64064.1 - 0.23 9.6 4.9 0.13 10.4 0.8 1.5 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.4 GAK64064.1 - 0.31 11.2 6.0 1.6 8.8 1.9 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 GAK64064.1 - 0.31 11.3 5.8 6.6 7.0 0.6 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 GAK64064.1 - 0.35 10.9 2.5 0.8 9.8 1.7 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 GAK64064.1 - 0.36 10.3 7.9 1.9 8.0 1.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sec20 PF03908.8 GAK64064.1 - 0.48 10.1 2.1 10 5.9 0.2 2.3 2 0 0 2 2 2 0 Sec20 Syntaxin PF00804.20 GAK64064.1 - 0.55 10.4 6.3 7.3 6.8 4.3 2.4 1 1 0 1 1 1 0 Syntaxin Apolipoprotein PF01442.13 GAK64064.1 - 0.56 9.6 8.1 1.7 8.1 5.6 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cluap1 PF10234.4 GAK64064.1 - 0.81 8.8 6.5 1.5 7.9 4.5 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 COG2 PF06148.6 GAK64064.1 - 1.4 8.8 7.3 2.5 8.0 1.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2408 PF10303.4 GAK64064.1 - 1.6 8.8 5.1 40 4.3 3.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Cortex-I_coil PF09304.5 GAK64064.1 - 1.7 8.7 11.5 6 6.9 2.5 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil Lectin_N PF03954.9 GAK64064.1 - 3.3 7.0 5.6 35 3.7 3.9 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain BAR PF03114.13 GAK64065.1 - 6.5e-20 71.6 0.1 9.9e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 BAR domain IncA PF04156.9 GAK64065.1 - 0.06 12.9 1.7 0.13 11.8 1.2 1.5 1 0 0 1 1 1 0 IncA protein DUF2203 PF09969.4 GAK64065.1 - 0.11 12.7 0.7 0.27 11.4 0.5 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) APG6 PF04111.7 GAK64065.1 - 0.14 11.1 3.8 0.29 10.1 2.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-B_dimeris PF09026.5 GAK64065.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.9 4 0 0 4 4 4 0 Centromere protein B dimerisation domain FemAB PF02388.11 GAK64065.1 - 1.4 7.5 7.5 0.1 11.2 2.0 1.4 2 0 0 2 2 2 0 FemAB family LCAT PF02450.10 GAK64066.1 - 1.2e-06 27.8 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 GAK64066.1 - 6.6e-06 26.1 2.2 7.6e-06 25.9 0.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAK64066.1 - 0.0024 17.5 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 GAK64066.1 - 0.037 13.5 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1748 PF08520.5 GAK64067.1 - 6.7e-28 96.1 0.0 7.6e-28 95.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Nup54 PF13874.1 GAK64068.1 - 1.3e-27 96.1 1.7 1.3e-27 96.1 1.2 2.8 4 0 0 4 4 4 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 GAK64068.1 - 0.51 10.5 102.0 4.7e+02 1.0 37.6 3.4 1 1 1 2 2 2 0 Nucleoporin FG repeat region Lactonase PF10282.4 GAK64069.1 - 1.4e-72 244.6 0.5 1.9e-72 244.2 0.4 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Pheromone PF08015.6 GAK64070.1 - 0.79 10.5 7.0 30 5.5 0.0 2.8 2 0 0 2 2 2 0 Fungal mating-type pheromone Coprogen_oxidas PF01218.13 GAK64071.1 - 3e-109 364.1 4.7 5.1e-37 127.0 0.0 3.3 4 0 0 4 4 4 3 Coproporphyrinogen III oxidase Mg_trans_NIPA PF05653.9 GAK64072.1 - 8.3e-64 215.3 4.7 1.2e-60 205.0 2.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 GAK64072.1 - 1.2e-07 31.9 9.3 6.4e-06 26.3 0.1 2.8 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 GAK64072.1 - 0.00089 19.2 5.4 0.00089 19.2 3.7 3.7 3 1 1 4 4 4 1 EamA-like transporter family Zip PF02535.17 GAK64072.1 - 3.1 6.7 12.0 26 3.6 6.1 3.2 3 0 0 3 3 3 0 ZIP Zinc transporter zf-C2H2 PF00096.21 GAK64073.1 - 6.8e-07 29.2 18.0 0.00021 21.4 0.6 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK64073.1 - 3.1e-06 27.1 5.4 3.1e-06 27.1 3.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAK64073.1 - 2.8e-05 24.1 10.5 0.0049 17.1 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAK64073.1 - 2.2 8.5 9.3 21 5.4 3.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CUE PF02845.11 GAK64074.1 - 1.5e-10 40.3 0.0 2.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.6 GAK64074.1 - 0.049 13.5 0.1 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Rsm22 PF09243.5 GAK64074.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DSPc PF00782.15 GAK64075.1 - 5.5e-27 93.9 0.9 8.2e-27 93.4 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAK64075.1 - 0.0029 17.0 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 GAK64075.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAK64075.1 - 0.026 14.7 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family TPR_11 PF13414.1 GAK64077.1 - 3.3e-15 55.4 9.5 5e-13 48.4 4.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAK64077.1 - 2.7e-10 39.3 10.4 2.6e-06 26.7 0.8 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAK64077.1 - 1.8e-09 36.8 12.7 0.00017 21.2 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAK64077.1 - 1.3e-08 34.6 10.9 9.1e-06 25.5 3.3 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAK64077.1 - 9.6e-08 31.7 2.4 9.6e-08 31.7 1.7 1.7 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAK64077.1 - 1.8e-06 27.7 6.4 0.0039 17.2 0.6 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK64077.1 - 7.3e-06 26.5 10.0 5.4e-05 23.7 5.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat NYD-SP12_N PF15015.1 GAK64077.1 - 8.9e-06 24.2 0.5 1.1e-05 23.8 0.3 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_14 PF13428.1 GAK64077.1 - 2.2e-05 24.7 4.7 0.013 16.0 0.2 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAK64077.1 - 2.3e-05 23.8 2.3 0.16 11.7 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 GAK64077.1 - 7e-05 22.8 2.3 0.00016 21.7 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAK64077.1 - 0.0002 20.5 2.3 0.1 11.6 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAK64077.1 - 0.00073 19.8 4.4 0.00073 19.8 3.1 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAK64077.1 - 0.0012 19.1 2.9 1.5 9.4 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAK64077.1 - 0.003 17.2 1.4 0.14 12.0 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 GAK64077.1 - 0.03 14.1 1.8 0.68 9.7 0.2 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.1 GAK64077.1 - 0.046 13.6 0.2 0.046 13.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Malic_M PF03949.10 GAK64078.1 - 2.1e-79 266.6 0.0 3e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 GAK64078.1 - 7.7e-67 224.3 0.0 1.2e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RhoGEF PF00621.15 GAK64079.1 - 4.4e-18 65.7 0.0 7.6e-14 51.9 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain SAP30_Sin3_bdg PF13867.1 GAK64080.1 - 0.004 16.9 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.24 GAK64081.1 - 3.6e-07 29.7 9.1 6.6e-07 28.9 6.3 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 GAK64081.1 - 0.027 14.1 4.6 0.053 13.2 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4206 PF13901.1 GAK64081.1 - 0.42 10.1 4.8 0.82 9.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Mitochondr_Som1 PF11093.3 GAK64083.1 - 3.2e-08 33.2 0.7 5.1e-08 32.6 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Alpha-amylase PF00128.19 GAK64084.1 - 2.4e-29 102.7 2.5 1.1e-24 87.4 0.1 2.7 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 GAK64084.1 - 8.4e-11 40.3 0.6 0.00059 17.7 0.0 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 GAK64084.1 - 0.00026 20.8 1.1 0.00095 19.0 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) RRM_1 PF00076.17 GAK64088.1 - 1.5e-38 130.2 0.0 9.9e-16 57.1 0.0 4.9 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64088.1 - 1e-33 115.1 0.0 1.5e-13 50.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64088.1 - 3.1e-16 58.9 0.0 9.9e-10 38.1 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAK64088.1 - 0.041 13.7 0.0 1.5 8.7 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif G_glu_transpept PF01019.16 GAK64089.1 - 1.1e-153 512.4 0.0 1.4e-153 512.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1664 PF07889.7 GAK64090.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) HisKA PF00512.20 GAK64090.1 - 0.045 13.7 1.9 1.1 9.3 0.0 2.7 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Syntaxin PF00804.20 GAK64090.1 - 0.064 13.4 2.3 0.18 11.9 0.9 1.8 2 0 0 2 2 2 0 Syntaxin Syntaxin-6_N PF09177.6 GAK64090.1 - 0.064 13.6 0.5 0.28 11.6 0.2 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Prominin PF05478.6 GAK64090.1 - 0.09 10.2 0.9 0.13 9.7 0.6 1.1 1 0 0 1 1 1 0 Prominin CHASE3 PF05227.8 GAK64090.1 - 0.12 12.0 3.4 0.067 12.8 0.4 2.0 2 1 0 2 2 2 0 CHASE3 domain FlaC_arch PF05377.6 GAK64090.1 - 0.24 11.3 1.5 0.58 10.0 0.2 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FlgN PF05130.7 GAK64090.1 - 0.42 10.8 7.1 0.16 12.2 1.2 2.0 2 0 0 2 2 2 0 FlgN protein UPF0183 PF03676.9 GAK64091.1 - 1.6e-29 102.7 0.8 2.4e-09 36.2 0.7 5.5 4 2 0 4 4 4 4 Uncharacterised protein family (UPF0183) zf-Apc11 PF12861.2 GAK64092.1 - 1.8e-32 111.0 11.0 2.4e-32 110.6 7.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAK64092.1 - 1.3e-28 98.8 11.3 1.6e-28 98.5 7.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAK64092.1 - 7.1e-08 32.1 16.3 2.5e-07 30.4 11.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAK64092.1 - 0.00026 20.9 12.0 0.01 15.8 7.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK64092.1 - 0.00059 19.4 13.3 0.0069 16.0 9.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK64092.1 - 0.00088 18.8 12.4 0.0039 16.8 8.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK64092.1 - 0.029 14.0 14.7 0.25 11.1 10.3 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Tax PF02959.11 GAK64092.1 - 0.072 12.5 1.7 0.088 12.2 1.2 1.1 1 0 0 1 1 1 0 HTLV Tax FANCL_C PF11793.3 GAK64092.1 - 0.56 10.2 13.5 2 8.4 9.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 GAK64092.1 - 0.6 10.1 8.7 0.71 9.8 5.6 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.1 GAK64092.1 - 0.62 9.7 16.5 4.1 7.0 8.6 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RRN7 PF11781.3 GAK64092.1 - 2.1 7.9 8.2 9.9 5.7 2.6 2.9 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-HC5HC2H PF13771.1 GAK64092.1 - 2.7 8.2 10.9 2 8.6 6.2 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 GAK64092.1 - 9.2 6.3 13.4 30 4.7 9.3 2.0 1 1 0 1 1 1 0 RING-like domain Ish1 PF10281.4 GAK64093.1 - 3e-56 187.0 25.0 7.3e-11 41.9 0.1 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein LEM PF03020.10 GAK64093.1 - 0.0056 16.1 0.0 19 4.7 0.0 4.6 6 0 0 6 6 6 1 LEM domain APC2 PF08672.6 GAK64093.1 - 0.013 15.7 0.0 57 4.0 0.0 4.5 5 0 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 SAP PF02037.22 GAK64093.1 - 0.048 13.1 0.0 56 3.4 0.0 4.1 5 0 0 5 5 5 0 SAP domain TryThrA_C PF12319.3 GAK64093.1 - 0.14 11.2 6.4 0.073 12.2 2.5 1.8 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Macoilin PF09726.4 GAK64093.1 - 3.1 5.9 15.0 4.4 5.4 10.4 1.3 1 0 0 1 1 1 0 Transmembrane protein PIG-F PF06699.6 GAK64094.1 - 2e-13 50.6 2.0 2.7e-13 50.3 1.4 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Na_H_Exchanger PF00999.16 GAK64095.1 - 1.2e-61 208.3 17.8 1.6e-61 207.9 12.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 GAK64095.1 - 0.052 13.5 0.6 0.31 10.9 0.0 2.3 2 0 0 2 2 2 0 YrhC-like protein DDE_3 PF13358.1 GAK64096.1 - 4.7e-31 107.5 0.0 7.8e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.13 GAK64096.1 - 4.8e-06 26.2 0.0 2.5e-05 24.0 0.0 2.1 3 0 0 3 3 3 1 'Paired box' domain HTH_28 PF13518.1 GAK64096.1 - 0.00087 19.2 0.0 0.0056 16.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_1 PF03184.14 GAK64096.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Ftsk_gamma PF09397.5 GAK64096.1 - 0.0018 17.9 0.0 0.0059 16.2 0.0 1.8 1 0 0 1 1 1 1 Ftsk gamma domain HTH_29 PF13551.1 GAK64096.1 - 0.023 14.8 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.1 GAK64096.1 - 0.067 12.8 0.1 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain MerR_1 PF13411.1 GAK64096.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein KAT11 PF08214.6 GAK64097.1 - 9.3e-30 103.8 0.0 1.1e-22 80.6 0.0 2.2 2 0 0 2 2 2 2 Histone acetylation protein Nt_Gln_amidase PF09764.4 GAK64098.1 - 8.7e-30 103.3 0.0 6.5e-13 48.3 0.0 3.1 2 1 0 2 2 2 2 N-terminal glutamine amidase DUF962 PF06127.6 GAK64099.1 - 7.3e-23 80.2 0.0 1.7e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DER1 PF04511.10 GAK64100.1 - 7.9e-49 165.8 1.8 1e-48 165.4 1.3 1.1 1 0 0 1 1 1 1 Der1-like family PRP1_N PF06424.7 GAK64100.1 - 9e-44 149.0 3.0 9e-44 149.0 2.1 1.8 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 GAK64100.1 - 2.9e-25 86.4 39.8 0.015 15.8 0.7 13.7 7 6 7 14 14 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 GAK64100.1 - 3.1e-14 53.1 36.1 0.034 14.8 2.8 9.1 7 2 2 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 GAK64100.1 - 4.1e-14 52.6 17.7 0.0016 18.7 0.1 9.8 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAK64100.1 - 8.9e-06 25.2 0.1 0.55 9.9 0.0 6.2 5 2 2 7 7 7 1 TPR repeat TPR_2 PF07719.12 GAK64100.1 - 0.00024 20.7 2.5 3.5 7.7 0.1 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat NRDE-2 PF08424.5 GAK64100.1 - 3.2 6.5 16.9 0.88 8.3 0.3 5.0 6 0 0 6 6 6 0 NRDE-2, necessary for RNA interference HSF_DNA-bind PF00447.12 GAK64101.1 - 1.4e-20 73.3 0.0 2.6e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Xpo1 PF08389.7 GAK64103.1 - 7.1e-19 68.1 0.4 7.9e-16 58.3 0.0 4.4 5 0 0 5 5 5 1 Exportin 1-like protein HEAT PF02985.17 GAK64103.1 - 0.006 16.5 1.0 1.2 9.4 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat Thi4 PF01946.12 GAK64104.1 - 1.6e-93 312.0 0.2 1.9e-93 311.8 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 GAK64104.1 - 8.3e-09 34.8 1.3 3.9e-08 32.5 0.5 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK64104.1 - 8.4e-08 32.1 0.1 2.5e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAK64104.1 - 4.6e-07 29.0 0.4 2.2e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAK64104.1 - 1.5e-06 27.2 1.3 2.3e-05 23.4 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 GAK64104.1 - 2.9e-06 27.1 0.1 6.2e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAK64104.1 - 3.7e-06 26.9 0.1 8.9e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK64104.1 - 0.00035 19.1 0.2 0.00053 18.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAK64104.1 - 0.0012 18.9 0.6 0.0047 17.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAK64104.1 - 0.0049 15.7 0.0 0.024 13.5 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAK64104.1 - 0.0054 15.4 0.1 0.0079 14.8 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 GAK64104.1 - 0.013 14.5 1.2 0.025 13.6 0.9 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAK64104.1 - 0.09 12.8 0.1 0.72 9.9 0.0 2.3 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF4387 PF14330.1 GAK64104.1 - 0.13 12.6 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4387) Amino_oxidase PF01593.19 GAK64104.1 - 0.14 11.1 0.0 0.32 10.0 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Ribosomal_L6e PF01159.14 GAK64106.1 - 2.1e-38 130.8 1.1 2.1e-38 130.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 GAK64106.1 - 0.0022 17.8 0.5 0.0022 17.8 0.3 2.5 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain Pet127 PF08634.5 GAK64107.1 - 7.4e-113 376.2 0.2 1.1e-112 375.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 CAF-1_p150 PF11600.3 GAK64107.1 - 1.2 8.4 6.2 3.2 7.0 4.3 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Scaffolding_pro PF11418.3 GAK64108.1 - 0.42 10.9 6.0 2 8.7 1.2 2.5 2 0 0 2 2 2 0 Phi29 scaffolding protein Las1 PF04031.8 GAK64111.1 - 6.3e-48 162.3 0.2 1.5e-47 161.1 0.1 1.6 1 0 0 1 1 1 1 Las1-like DnaJ-X PF14308.1 GAK64112.1 - 1.2e-42 145.4 2.8 1.2e-42 145.4 2.0 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 GAK64112.1 - 6.3e-26 89.9 1.1 1.8e-25 88.4 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain OmdA PF13376.1 GAK64112.1 - 0.053 13.1 2.5 0.19 11.4 1.8 2.0 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Zip PF02535.17 GAK64112.1 - 0.14 11.1 10.6 0.028 13.4 4.5 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Innate_immun PF12782.2 GAK64112.1 - 1.4 8.0 10.2 2.6 7.1 7.1 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SSP160 PF06933.6 GAK64112.1 - 4.3 5.1 23.0 9.7 4.0 15.9 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SelP_N PF04592.9 GAK64112.1 - 6 6.1 19.9 0.039 13.3 7.4 2.0 3 0 0 3 3 3 0 Selenoprotein P, N terminal region UCH PF00443.24 GAK64113.1 - 2.2e-44 151.6 0.0 2.7e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK64113.1 - 6.8e-18 65.1 0.0 9.7e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pantoate_ligase PF02569.10 GAK64113.1 - 0.35 9.5 1.3 0.38 9.4 0.1 1.5 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Fork_head PF00250.13 GAK64114.1 - 1.1e-10 41.4 0.0 3.3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Fork head domain PAT1 PF09770.4 GAK64114.1 - 1.4 7.0 85.2 0.17 10.1 36.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CTP_transf_1 PF01148.15 GAK64117.1 - 4.7e-70 236.2 25.8 1.8e-69 234.2 17.9 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family TFIIA PF03153.8 GAK64117.1 - 0.00061 19.7 17.3 0.00085 19.3 12.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 GAK64118.1 - 2.1e-64 217.1 0.0 2.8e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64118.1 - 2.6e-44 151.2 0.0 3.7e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK64118.1 - 4.1e-08 32.5 0.0 1.5e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 GAK64118.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family T2SF PF00482.18 GAK64120.1 - 0.027 14.3 0.1 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Peptidase_C15 PF01470.12 GAK64121.1 - 8.8e-10 38.7 0.0 0.00064 19.6 0.0 2.5 3 1 0 3 3 3 2 Pyroglutamyl peptidase CBF PF03914.12 GAK64122.1 - 6.7e-44 149.2 0.0 4.2e-43 146.6 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.15 GAK64122.1 - 0.021 13.1 0.2 1 7.6 0.0 2.6 3 1 0 3 3 3 0 Adaptin N terminal region DPBB_1 PF03330.13 GAK64123.1 - 7.6e-06 25.8 0.5 1.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SAPS PF04499.10 GAK64123.1 - 0.007 15.0 6.6 0.012 14.2 4.6 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Hid1 PF12722.2 GAK64123.1 - 0.88 7.1 18.2 1.1 6.9 12.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 GAK64123.1 - 2.3 6.3 22.4 3.1 5.9 15.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_3 PF13922.1 GAK64123.1 - 5 7.4 10.1 21 5.4 7.0 2.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Sporozoite_P67 PF05642.6 GAK64123.1 - 5.7 4.6 24.0 9.4 3.9 16.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4407 PF14362.1 GAK64123.1 - 6.1 5.6 14.1 7.4 5.4 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIF_alpha PF05793.7 GAK64123.1 - 7.6 4.7 23.9 11 4.2 16.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CLASP_N PF12348.3 GAK64125.1 - 1.3e-27 96.6 0.0 1.8e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal ABC_membrane PF00664.18 GAK64126.1 - 6.3e-43 147.1 2.3 6.3e-43 147.1 1.6 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 GAK64126.1 - 3.8e-32 111.4 0.0 7.4e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.4 GAK64126.1 - 0.0012 17.5 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_21 PF13304.1 GAK64126.1 - 0.003 17.5 0.0 0.32 10.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAK64126.1 - 0.0031 16.7 0.0 0.037 13.2 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAK64126.1 - 0.043 13.2 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAK64126.1 - 0.044 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PMSI1 PF15322.1 GAK64127.1 - 0.025 13.6 0.3 0.025 13.6 0.2 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Zn_clus PF00172.13 GAK64128.1 - 1.6e-06 27.9 10.2 1.6e-06 27.9 7.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 GAK64128.1 - 0.00056 20.1 0.0 0.00056 20.1 0.0 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK64128.1 - 0.0022 18.1 0.1 0.0022 18.1 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger PACT_coil_coil PF10495.4 GAK64129.1 - 8.4e-10 38.4 0.7 3.9e-09 36.3 0.5 2.3 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DDHD PF02862.12 GAK64130.1 - 1.4e-44 152.5 0.7 6.2e-43 147.2 0.0 2.8 2 0 0 2 2 2 1 DDHD domain Kri1_C PF12936.2 GAK64130.1 - 0.012 15.4 0.5 0.036 14.0 0.4 1.7 1 0 0 1 1 1 0 KRI1-like family C-terminal Abhydrolase_5 PF12695.2 GAK64130.1 - 0.022 14.5 0.0 0.081 12.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3498 PF12004.3 GAK64131.1 - 0.0023 17.1 1.5 0.0025 17.0 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) Aa_trans PF01490.13 GAK64132.1 - 3.2e-73 246.5 17.1 3.2e-73 246.5 11.9 1.7 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 GAK64132.1 - 0.00037 19.4 10.6 0.00037 19.4 7.3 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Hexapep PF00132.19 GAK64133.1 - 6.9e-06 25.3 3.4 0.00059 19.2 1.1 3.4 1 1 2 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAK64133.1 - 8.4e-05 22.6 1.5 0.0001 22.4 0.1 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 GAK64133.1 - 0.0043 16.3 0.0 0.035 13.4 0.1 2.2 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.1 GAK64133.1 - 0.0088 15.5 5.5 0.27 10.8 3.8 2.5 1 1 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 GAK64133.1 - 0.032 13.8 0.0 0.088 12.4 0.0 1.7 1 0 0 1 1 1 0 Cytidylyltransferase Sec1 PF00995.18 GAK64134.1 - 3e-150 501.5 0.0 3.4e-150 501.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Hydrolase_6 PF13344.1 GAK64135.1 - 2.2e-08 33.9 0.0 4.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hexapep PF00132.19 GAK64135.1 - 4e-08 32.3 15.5 3.8e-05 22.9 1.9 5.1 4 1 1 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hydrolase_like PF13242.1 GAK64135.1 - 2.1e-06 27.3 0.0 2.4e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hexapep_2 PF14602.1 GAK64135.1 - 0.00048 19.6 1.7 0.00048 19.6 1.2 4.3 4 1 1 5 5 5 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 GAK64135.1 - 0.027 13.0 0.2 0.044 12.3 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase Fungal_trans PF04082.13 GAK64136.1 - 7.1e-14 51.3 0.1 1.7e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK64136.1 - 1.8e-06 27.7 9.7 3.7e-06 26.7 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EamA PF00892.15 GAK64137.1 - 1.2e-26 93.2 32.2 1e-15 57.8 5.5 3.1 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 GAK64137.1 - 2e-06 27.9 4.7 2e-06 27.9 3.3 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter DUF1469 PF07332.6 GAK64137.1 - 0.0072 16.0 3.5 0.0072 16.0 2.4 4.5 3 1 2 5 5 5 1 Protein of unknown function (DUF1469) TPT PF03151.11 GAK64137.1 - 0.31 10.6 18.8 0.32 10.6 4.0 3.2 2 2 0 2 2 2 0 Triose-phosphate Transporter family WD40 PF00400.27 GAK64138.1 - 7.8e-47 155.5 20.5 4.8e-10 38.9 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Pkinase PF00069.20 GAK64139.1 - 1.3e-67 227.7 0.0 1.9e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64139.1 - 6.4e-56 189.2 0.0 1e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 GAK64139.1 - 2.5e-07 30.3 6.8 2.5e-07 30.3 4.7 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 GAK64139.1 - 3.4e-05 23.8 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Kinase-like PF14531.1 GAK64139.1 - 0.00014 20.9 0.0 0.0017 17.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like CDC24 PF06395.6 GAK64139.1 - 0.00015 21.7 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin RIO1 PF01163.17 GAK64139.1 - 0.0081 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 GAK64139.1 - 0.012 14.4 0.2 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CAMSAP_CH PF11971.3 GAK64139.1 - 0.045 13.4 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Herpes_gE PF02480.11 GAK64140.1 - 0.00037 18.8 0.2 0.00058 18.2 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 GAK64140.1 - 0.00063 19.4 0.5 0.0011 18.6 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF3404 PF11884.3 GAK64140.1 - 0.0079 15.1 0.3 0.092 11.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3404) Rifin_STEVOR PF02009.11 GAK64140.1 - 0.0086 15.7 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Rifin/stevor family CD34_antigen PF06365.7 GAK64140.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF1218 PF06749.7 GAK64140.1 - 0.037 14.4 1.3 0.099 13.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) EphA2_TM PF14575.1 GAK64140.1 - 0.06 13.7 0.3 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SCF PF02404.10 GAK64140.1 - 0.087 12.0 0.1 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Stem cell factor Epiglycanin_C PF14654.1 GAK64140.1 - 0.091 12.7 0.1 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Sua5_yciO_yrdC PF01300.13 GAK64141.1 - 4.6e-49 166.0 0.1 1.6e-48 164.3 0.0 1.9 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 GAK64141.1 - 3.2e-26 91.8 0.0 1.1e-25 90.1 0.0 1.9 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding GST_N_3 PF13417.1 GAK64142.1 - 6.5e-10 39.0 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAK64142.1 - 7e-10 38.9 0.0 1.8e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAK64142.1 - 1.5e-09 37.7 0.0 3.8e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAK64142.1 - 2.5e-09 36.8 0.0 6.9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAK64142.1 - 1.3e-07 31.5 0.0 3.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAK64142.1 - 0.00014 22.2 0.3 0.00096 19.5 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain DUF1242 PF06842.7 GAK64143.1 - 2.1e-17 62.2 0.5 3.5e-17 61.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Prenyltrans_2 PF13249.1 GAK64144.1 - 1.6e-38 131.6 7.3 4.8e-17 62.3 0.1 5.5 3 3 3 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 GAK64144.1 - 1.1e-33 114.4 9.3 1.9e-09 36.9 0.1 6.9 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 GAK64144.1 - 9.8e-28 96.3 0.3 5.1e-13 48.9 0.2 5.5 3 2 2 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 GAK64144.1 - 2.4e-08 33.4 0.3 0.33 10.0 0.0 4.9 2 1 2 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 GAK64144.1 - 1.4e-07 30.9 0.2 7.8e-05 22.0 0.0 3.4 3 1 1 4 4 4 1 A-macroglobulin complement component DUF1925 PF09094.6 GAK64144.1 - 0.023 14.6 0.1 11 6.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) MPLKIP PF15502.1 GAK64145.1 - 5.1 7.7 13.1 4.4 7.9 7.8 1.9 1 1 0 1 1 1 0 M-phase-specific PLK1-interacting protein DUF155 PF02582.9 GAK64146.1 - 2e-51 174.3 0.3 4e-51 173.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Nucleoplasmin PF03066.10 GAK64146.1 - 0.25 10.8 11.0 0.67 9.4 7.6 1.7 1 0 0 1 1 1 0 Nucleoplasmin Dus PF01207.12 GAK64147.1 - 1.5e-47 161.9 0.0 8.9e-33 113.4 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF3487 PF11990.3 GAK64147.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) ATP-synt_C PF00137.16 GAK64148.1 - 4.6e-28 96.8 33.9 2.3e-17 62.6 8.4 2.7 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 GAK64148.1 - 0.82 9.3 8.0 0.26 10.8 1.8 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ribosomal_L34 PF00468.12 GAK64149.1 - 2e-14 52.9 9.6 3e-14 52.4 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 DUF2637 PF10935.3 GAK64149.1 - 0.032 14.1 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) Aldedh PF00171.17 GAK64150.1 - 2.8e-14 52.3 6.1 1.4e-12 46.6 3.7 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family HSP70 PF00012.15 GAK64151.1 - 9.4e-161 535.7 0.3 1.4e-160 535.1 0.1 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAK64151.1 - 4.5e-12 45.1 0.0 1.2e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein zf-C3Hc3H PF13891.1 GAK64151.1 - 0.24 11.5 0.1 0.61 10.1 0.0 1.6 2 0 0 2 2 2 0 Potential DNA-binding domain FAD_binding_7 PF03441.9 GAK64152.1 - 3.7e-62 210.0 1.8 5.1e-62 209.5 1.2 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAK64152.1 - 9.8e-22 77.4 0.0 2.3e-21 76.2 0.0 1.5 1 1 0 1 1 1 1 DNA photolyase Flavoprotein PF02441.14 GAK64153.1 - 1.1e-37 128.6 0.2 2e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 Flavoprotein VPS9 PF02204.13 GAK64153.1 - 3.4e-27 94.5 0.0 6.1e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Phage_Nu1 PF07471.7 GAK64153.1 - 0.0096 15.4 0.1 0.029 13.8 0.1 1.8 1 0 0 1 1 1 1 Phage DNA packaging protein Nu1 GATase_4 PF13230.1 GAK64154.1 - 8.4e-20 70.5 0.0 2e-19 69.3 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAK64154.1 - 1.1e-10 41.5 0.0 6.6e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 GAK64154.1 - 1.6e-08 33.6 0.0 2e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 GAK64154.1 - 0.039 13.6 0.0 0.88 9.3 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase domain DUF1454 PF07305.7 GAK64154.1 - 0.15 11.1 0.0 0.34 9.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1454) Pkinase PF00069.20 GAK64155.1 - 6.4e-28 97.6 0.0 1.8e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64155.1 - 1.3e-12 47.3 0.0 2.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cyclin PF08613.6 GAK64156.1 - 5.1e-15 56.1 0.0 1.4e-12 48.2 0.0 2.5 2 1 0 2 2 2 2 Cyclin PNGaseA PF12222.3 GAK64157.1 - 2.2e-63 214.6 0.0 2.1e-62 211.4 0.0 2.0 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A COQ7 PF03232.8 GAK64157.1 - 3e-61 205.8 0.0 1.5e-60 203.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 FAD_binding_3 PF01494.14 GAK64157.1 - 3.8e-15 55.8 5.6 1.5e-08 34.0 0.1 3.5 4 0 0 4 4 4 2 FAD binding domain SE PF08491.5 GAK64157.1 - 0.0023 16.7 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 GAK64157.1 - 0.023 15.0 0.1 0.088 13.2 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XPG_N PF00752.12 GAK64158.1 - 7.4e-35 119.2 0.0 1.5e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 GAK64158.1 - 9.4e-29 99.3 0.0 2.5e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 GAK64158.1 - 4e-08 33.4 0.0 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF4192 PF13830.1 GAK64158.1 - 0.028 14.0 0.4 0.67 9.5 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) TniB PF05621.6 GAK64158.1 - 0.029 13.1 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein HHH_5 PF14520.1 GAK64158.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 GAK64158.1 - 0.049 13.1 0.0 0.17 11.4 0.0 2.0 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_2 PF12826.2 GAK64158.1 - 0.057 13.3 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif TMF_DNA_bd PF12329.3 GAK64159.1 - 6.2e-05 22.7 5.5 6.2e-05 22.7 3.8 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Macoilin PF09726.4 GAK64159.1 - 0.43 8.7 10.5 0.91 7.7 7.3 1.5 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 GAK64159.1 - 3.4 6.5 13.0 5.6 5.8 9.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PX PF00787.19 GAK64160.1 - 2.6e-25 88.4 0.1 3.6e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 PX domain DUF641 PF04859.7 GAK64161.1 - 0.1 12.3 11.7 0.38 10.5 0.4 3.7 4 0 0 4 4 4 0 Plant protein of unknown function (DUF641) Myosin_tail_1 PF01576.14 GAK64161.1 - 0.11 10.1 31.9 0.041 11.6 11.1 3.3 2 1 0 2 2 2 0 Myosin tail COG2 PF06148.6 GAK64161.1 - 7.1 6.5 14.7 3.2 7.6 0.2 4.3 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DAP3 PF10236.4 GAK64162.1 - 4.9e-72 242.4 2.2 6.4e-72 242.0 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 GAK64162.1 - 4.1e-08 33.2 0.8 3.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 GAK64162.1 - 2.2e-07 31.0 1.5 2.2e-07 31.0 1.0 2.6 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAK64162.1 - 0.0003 20.9 1.1 0.0014 18.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK64162.1 - 0.0052 16.5 0.0 0.019 14.6 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 GAK64162.1 - 0.006 16.0 0.8 0.014 14.8 0.1 1.9 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 GAK64162.1 - 0.02 14.5 4.7 0.02 14.5 0.0 3.0 3 1 0 3 3 3 0 Helicase AAA_14 PF13173.1 GAK64162.1 - 0.054 13.3 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain PEP-utilizers PF00391.18 GAK64162.1 - 0.088 12.3 2.0 8.9 5.9 0.1 3.5 4 0 0 4 4 4 0 PEP-utilising enzyme, mobile domain WD40 PF00400.27 GAK64163.1 - 1.9e-15 56.0 9.4 7.2e-06 25.6 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DPPIV_N PF00930.16 GAK64163.1 - 0.016 13.8 0.5 0.75 8.3 0.4 2.5 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Rax2 PF12768.2 GAK64163.1 - 0.044 12.9 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Pkinase PF00069.20 GAK64164.1 - 3.9e-46 157.3 0.0 8.2e-46 156.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64164.1 - 9e-17 60.9 0.0 3.7e-16 58.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK64164.1 - 3.3e-06 27.0 0.1 8.1e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAK64164.1 - 0.0008 18.4 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK64164.1 - 0.00088 18.3 0.2 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_q6 PF01058.17 GAK64165.1 - 5.2e-21 74.6 0.1 8.4e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit V-SNARE_C PF12352.3 GAK64166.1 - 5.1e-16 58.5 0.4 1.3e-15 57.1 0.3 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 GAK64166.1 - 4e-06 26.4 0.0 1.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Sec20 Mito_fiss_reg PF05308.6 GAK64166.1 - 0.0032 16.8 0.4 0.0041 16.5 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator PspA_IM30 PF04012.7 GAK64166.1 - 0.018 14.3 0.2 0.036 13.4 0.1 1.5 1 0 0 1 1 1 0 PspA/IM30 family Wbp11 PF09429.5 GAK64166.1 - 0.079 12.9 0.8 0.37 10.8 0.5 2.1 1 1 1 2 2 2 0 WW domain binding protein 11 Methyltransf_31 PF13847.1 GAK64167.1 - 1.3e-11 44.3 0.1 1.8e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAK64167.1 - 1.2e-09 37.7 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 GAK64167.1 - 3.6e-09 37.1 0.0 9.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK64167.1 - 1e-07 32.3 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK64167.1 - 1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 GAK64167.1 - 1.3e-07 30.9 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 GAK64167.1 - 2.9e-06 27.3 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK64167.1 - 8.1e-06 26.2 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAK64167.1 - 3.7e-05 22.6 0.0 5.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 GAK64167.1 - 0.00012 22.3 0.0 0.00026 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK64167.1 - 0.00018 20.8 0.2 0.00041 19.7 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 GAK64167.1 - 0.00047 19.3 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 GAK64167.1 - 0.0018 18.2 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 GAK64167.1 - 0.064 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 GAK64167.1 - 0.098 12.0 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 GAK64167.1 - 0.11 13.3 0.0 0.31 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 GAK64167.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 GAK64167.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.10 GAK64167.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-CCHC PF00098.18 GAK64168.1 - 3.8e-14 51.8 21.4 9.5e-05 22.1 1.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 GAK64168.1 - 9.7e-07 28.3 22.4 0.01 15.4 0.5 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 GAK64168.1 - 2.7e-06 26.7 13.6 0.0049 16.3 0.8 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_6 PF15288.1 GAK64168.1 - 0.048 13.3 0.5 0.048 13.3 0.3 3.4 3 0 0 3 3 3 0 Zinc knuckle Sar8_2 PF03058.9 GAK64168.1 - 7.6 6.9 6.4 24 5.3 0.1 2.7 1 1 1 2 2 2 0 Sar8.2 family DER1 PF04511.10 GAK64169.1 - 3.3e-31 108.3 0.1 4.3e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Der1-like family Peptidase_M20 PF01546.23 GAK64170.1 - 4.9e-24 84.8 0.5 8.2e-24 84.1 0.3 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAK64170.1 - 1.7e-12 47.0 0.0 7.1e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAK64170.1 - 0.038 13.7 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 Peptidase family M28 F-box-like PF12937.2 GAK64171.1 - 0.0026 17.4 1.8 0.019 14.6 1.3 2.5 1 1 0 1 1 1 1 F-box-like A_deamin PF02137.13 GAK64173.1 - 5.1e-50 170.7 0.0 6.8e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Lactamase_B_2 PF12706.2 GAK64174.1 - 1.9e-30 105.8 0.2 4e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAK64174.1 - 2.2e-07 30.7 0.1 6.5e-06 25.9 0.1 3.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain adh_short PF00106.20 GAK64175.1 - 3e-29 102.0 0.2 4e-29 101.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK64175.1 - 1.5e-14 54.4 0.0 1.8e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK64175.1 - 2.8e-09 36.8 0.1 4.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAK64175.1 - 0.0001 22.3 0.1 0.00035 20.6 0.0 1.9 2 1 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 GAK64175.1 - 0.00016 20.9 0.0 0.00063 18.9 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAK64175.1 - 0.00016 21.1 0.0 0.00035 20.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAK64175.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SIR2 PF02146.12 GAK64176.1 - 3.7e-53 179.8 0.0 6.2e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Sir2 family AAA_33 PF13671.1 GAK64177.1 - 2.5e-15 56.6 0.4 1.9e-14 53.7 0.2 2.3 1 1 1 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.6 GAK64177.1 - 1.1e-06 28.6 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 GAK64177.1 - 1.6e-05 25.7 0.0 2.7e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAK64177.1 - 3.9e-05 23.7 0.1 9.6e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAK64177.1 - 0.002 18.4 0.0 0.0051 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 GAK64177.1 - 0.0034 16.9 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 GAK64177.1 - 0.011 14.8 0.0 0.03 13.4 0.0 1.7 1 1 1 2 2 2 0 Zeta toxin AAA_16 PF13191.1 GAK64177.1 - 0.02 14.8 0.2 0.036 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 GAK64177.1 - 0.03 13.2 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 GAK64177.1 - 0.054 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 GAK64177.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 GAK64177.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 GAK64177.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 GAK64177.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 MRP-S28 PF10213.4 GAK64178.1 - 1.2e-38 132.0 0.1 1.7e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ammonium_transp PF00909.16 GAK64179.1 - 2.1e-112 375.5 29.9 2.4e-112 375.3 20.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YuiB PF14068.1 GAK64179.1 - 6.6 7.1 10.2 0.99 9.7 3.8 2.2 2 0 0 2 2 2 0 Putative membrane protein TFIIS_M PF07500.9 GAK64180.1 - 2.2e-29 101.8 1.4 2.2e-29 101.8 0.9 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 GAK64180.1 - 5.2e-19 67.5 9.2 8.1e-19 66.9 6.4 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 GAK64180.1 - 1.2e-13 50.3 0.1 3.5e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SOG2 PF10428.4 GAK64180.1 - 0.0019 16.9 2.3 0.0028 16.3 1.6 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein zinc_ribbon_5 PF13719.1 GAK64180.1 - 0.051 13.1 4.2 0.11 12.0 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain HTH_22 PF13309.1 GAK64180.1 - 0.061 13.0 0.3 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 HTH domain Myc_target_1 PF15179.1 GAK64180.1 - 0.073 12.6 2.8 0.13 11.8 1.9 1.4 1 0 0 1 1 1 0 Myc target protein 1 zinc_ribbon_4 PF13717.1 GAK64180.1 - 0.1 12.2 4.3 0.23 11.1 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain RAP1 PF07218.6 GAK64180.1 - 0.29 9.1 8.4 0.36 8.8 5.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3138 PF11336.3 GAK64180.1 - 3.1 5.8 13.2 4.5 5.3 8.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1180 PF06679.7 GAK64180.1 - 7.8 6.3 8.7 4.1 7.2 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) WD40 PF00400.27 GAK64181.1 - 1.8e-52 173.4 11.6 2.3e-08 33.5 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Bromodomain PF00439.20 GAK64181.1 - 1.8e-21 75.8 0.1 3.4e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Nup160 PF11715.3 GAK64181.1 - 0.58 8.2 0.6 9.8 4.1 0.1 2.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CDC45 PF02724.9 GAK64181.1 - 1.5 6.7 21.3 0.53 8.2 0.6 2.3 2 0 0 2 2 2 0 CDC45-like protein FA_hydroxylase PF04116.8 GAK64182.1 - 6.1e-16 58.8 18.5 6.1e-16 58.8 12.8 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1708 PF08101.6 GAK64183.1 - 5.3e-19 68.3 0.8 5.7e-13 48.4 1.7 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 GAK64183.1 - 7.2e-07 28.9 0.0 3.5e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 RhoGAP domain FAM117 PF15388.1 GAK64184.1 - 1.6 7.9 14.5 3.4 6.7 10.0 1.5 1 0 0 1 1 1 0 Protein Family FAM117 Ribosomal_S10 PF00338.17 GAK64187.1 - 1.7e-22 79.0 0.0 3.7e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e BTB_2 PF02214.17 GAK64188.1 - 0.00013 22.0 0.0 0.014 15.5 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain Longin PF13774.1 GAK64189.1 - 5.4e-28 96.3 0.1 8.1e-28 95.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 GAK64189.1 - 2.2e-15 56.0 0.1 4.7e-15 54.9 0.0 1.6 1 1 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 GAK64189.1 - 0.0072 16.1 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DEAD PF00270.24 GAK64190.1 - 2e-10 40.4 0.0 4.1e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK64190.1 - 0.00098 18.9 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ACPS PF01648.15 GAK64192.1 - 4.5e-29 100.5 0.2 1.6e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily PLA2_B PF01735.13 GAK64192.1 - 1.6e-16 59.5 0.0 8e-13 47.3 0.0 3.0 3 0 0 3 3 3 3 Lysophospholipase catalytic domain Evr1_Alr PF04777.8 GAK64193.1 - 1.3e-28 98.7 0.1 6.8e-28 96.4 0.0 2.1 2 0 0 2 2 2 1 Erv1 / Alr family COX16 PF14138.1 GAK64193.1 - 1.2e-26 92.7 0.2 2e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Mito_carr PF00153.22 GAK64194.1 - 2.9e-67 222.4 6.2 2.2e-23 81.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2347 PF09804.4 GAK64195.1 - 5.1e-42 144.0 0.0 4.4e-40 137.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 GAK64195.1 - 0.048 13.6 0.3 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4298 PF14131.1 GAK64195.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Avl9 PF09794.4 GAK64195.1 - 0.23 9.9 0.0 0.85 8.0 0.0 1.8 1 1 0 1 1 1 0 Transport protein Avl9 Gluconate_2-dh3 PF13618.1 GAK64196.1 - 0.011 15.8 0.4 0.029 14.5 0.3 1.9 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Nucleoplasmin PF03066.10 GAK64196.1 - 0.018 14.5 1.0 0.032 13.7 0.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 GAK64196.1 - 0.12 12.6 3.8 0.091 13.0 1.4 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 GAK64196.1 - 0.24 10.9 7.3 0.13 11.8 2.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.1 GAK64196.1 - 0.78 9.9 7.1 1.5 8.9 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Complex1_LYR_2 PF13233.1 GAK64197.1 - 4.6e-13 49.5 0.6 4.6e-13 49.5 0.4 1.5 2 0 0 2 2 2 1 Complex1_LYR-like PALP PF00291.20 GAK64198.1 - 5.3e-53 180.2 1.5 2.2e-52 178.2 1.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_6 PF12697.2 GAK64198.1 - 0.013 15.3 0.4 0.052 13.4 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family ABC_trans_N PF14510.1 GAK64198.1 - 0.028 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Abhydrolase_5 PF12695.2 GAK64198.1 - 0.04 13.6 1.4 0.14 11.9 0.6 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family TPR_11 PF13414.1 GAK64199.1 - 3.9e-45 151.3 24.2 7.8e-16 57.4 0.8 6.7 3 3 4 8 8 8 8 TPR repeat TPR_1 PF00515.23 GAK64199.1 - 4e-36 121.1 20.6 4.7e-06 25.9 0.0 10.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAK64199.1 - 9.2e-33 109.5 21.6 0.00015 21.4 0.6 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAK64199.1 - 4.4e-21 75.0 18.4 0.00021 21.8 0.1 6.6 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAK64199.1 - 4.3e-20 71.4 16.4 3.6e-05 23.6 0.7 6.4 4 2 4 8 8 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAK64199.1 - 5.3e-18 63.6 10.9 0.0038 17.2 0.0 9.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAK64199.1 - 5.2e-17 60.2 15.4 0.0035 16.9 0.0 9.7 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAK64199.1 - 9.1e-13 47.6 19.7 0.49 11.1 0.1 10.9 5 4 8 13 13 11 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAK64199.1 - 6.2e-11 41.2 11.4 0.018 14.7 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 GAK64199.1 - 6.8e-11 42.1 14.9 0.047 13.8 0.3 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAK64199.1 - 7.4e-09 35.8 20.5 0.00065 19.9 1.0 6.2 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAK64199.1 - 1.5e-06 27.9 3.5 0.0037 17.0 0.0 5.4 3 2 1 5 5 5 1 Tetratricopeptide repeat Methyltrans_RNA PF04452.9 GAK64199.1 - 0.08 12.0 2.3 0.18 10.9 0.2 2.3 2 0 0 2 2 2 0 RNA methyltransferase SHNi-TPR PF10516.4 GAK64199.1 - 0.28 10.4 7.3 11 5.3 0.0 4.7 5 0 0 5 5 5 0 SHNi-TPR TPR_6 PF13174.1 GAK64199.1 - 0.67 10.5 25.8 16 6.2 0.1 8.3 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_3 PF07720.7 GAK64199.1 - 8.9 6.2 11.6 1.3 8.9 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF759 PF05537.6 GAK64200.1 - 0.056 12.2 0.0 0.059 12.1 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Spidroin_MaSp PF11260.3 GAK64200.1 - 0.13 12.3 2.6 0.16 12.0 1.8 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Pardaxin PF07425.6 GAK64200.1 - 0.29 10.5 11.3 2 7.8 3.0 3.1 1 1 1 2 2 2 0 Pardaxin SseC PF04888.7 GAK64200.1 - 0.53 9.5 6.4 0.9 8.8 4.4 1.5 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Antimicrobial_8 PF08103.6 GAK64200.1 - 1.2 9.2 4.8 3.7 7.6 0.2 3.0 1 1 2 3 3 3 0 Uperin family Coiled PF05710.7 GAK64200.1 - 9.2 6.8 10.2 20 5.7 7.1 1.8 1 1 0 1 1 1 0 Coiled coil Rad60-SLD PF11976.3 GAK64201.1 - 3.5e-26 90.6 0.5 4.6e-26 90.2 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAK64201.1 - 1.4e-12 46.8 0.1 1.9e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF4115 PF13464.1 GAK64201.1 - 0.043 13.4 0.0 0.085 12.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4115) LAG1-DNAbind PF09271.6 GAK64202.1 - 1.2e-25 90.5 0.1 3.9e-24 85.7 0.1 2.5 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 GAK64202.1 - 3.4e-18 65.9 0.0 6.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF3545 PF12065.3 GAK64202.1 - 0.22 11.2 0.1 0.49 10.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Cu-oxidase_3 PF07732.10 GAK64203.1 - 7.9e-45 151.3 2.5 7.8e-44 148.1 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAK64203.1 - 3.8e-31 107.4 10.8 1.5e-24 86.0 1.3 4.2 4 0 0 4 4 4 4 Multicopper oxidase Cu-oxidase PF00394.17 GAK64203.1 - 4e-27 95.0 0.0 9.7e-27 93.8 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Proteasome PF00227.21 GAK64204.1 - 4.1e-28 97.9 0.0 5.4e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 GAK64204.1 - 0.03 13.8 0.5 0.69 9.5 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Phyto_Pns9_10 PF05878.6 GAK64204.1 - 0.061 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 zf-met PF12874.2 GAK64205.1 - 1.1e-06 28.5 1.2 3e-06 27.2 0.6 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 GAK64205.1 - 0.047 12.9 0.4 0.091 12.0 0.3 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Syja_N PF02383.13 GAK64206.1 - 5.7e-91 304.5 0.0 8.4e-91 304.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain CbiN PF02553.10 GAK64206.1 - 0.078 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Cobalt transport protein component CbiN Exo_endo_phos PF03372.18 GAK64207.1 - 1.4e-12 48.0 0.0 3.2e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SR-25 PF10500.4 GAK64207.1 - 0.091 12.2 10.3 0.043 13.2 2.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2388 PF09498.5 GAK64208.1 - 0.02 14.5 0.0 8.6 6.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) HSA PF07529.8 GAK64209.1 - 5.1e-18 64.6 3.9 5.1e-18 64.6 2.7 4.8 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.1 GAK64209.1 - 4.4e-07 29.9 0.2 4.4e-07 29.9 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Gti1_Pac2 PF09729.4 GAK64210.1 - 4.6e-58 195.8 0.0 9.9e-58 194.7 0.0 1.6 1 0 0 1 1 1 1 Gti1/Pac2 family Amino_oxidase PF01593.19 GAK64211.1 - 2.9e-46 158.4 4.7 1.3e-31 110.2 0.5 2.9 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAK64211.1 - 2.4e-12 46.7 0.3 8.9e-12 44.8 0.2 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK64211.1 - 6.8e-10 38.3 0.3 2e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK64211.1 - 7.7e-10 37.8 0.5 2.4e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 GAK64211.1 - 1.4e-08 34.0 0.1 2.6e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAK64211.1 - 2e-08 34.5 0.5 7e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAK64211.1 - 1.1e-07 31.9 0.0 2e-06 27.8 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK64211.1 - 5.9e-07 28.8 0.2 1e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAK64211.1 - 1e-06 28.9 0.0 5.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAK64211.1 - 4.5e-06 25.9 1.2 6.2e-05 22.2 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 GAK64211.1 - 4.6e-06 25.9 0.1 8.1e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAK64211.1 - 1.3e-05 24.3 0.5 0.00014 20.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAK64211.1 - 0.00017 21.3 0.6 0.012 15.3 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 GAK64211.1 - 0.00022 20.2 0.1 0.00022 20.2 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Hexapep_2 PF14602.1 GAK64213.1 - 1.3e-12 47.0 5.7 3e-10 39.4 2.2 2.2 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 GAK64213.1 - 1.9e-12 46.0 7.8 3.8e-10 38.7 3.2 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 GAK64213.1 - 2.1e-09 37.2 0.4 8.7e-09 35.2 0.3 1.9 2 0 0 2 2 2 1 Maltose acetyltransferase DinB_2 PF12867.2 GAK64213.1 - 0.048 14.0 0.1 0.071 13.4 0.1 1.2 1 0 0 1 1 1 0 DinB superfamily tRNA-synt_1b PF00579.20 GAK64214.1 - 7.7e-62 209.0 0.0 2e-61 207.7 0.0 1.7 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) MutS_V PF00488.16 GAK64215.1 - 8.7e-78 260.9 0.0 1.5e-77 260.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAK64215.1 - 4.3e-50 170.3 5.9 7.3e-50 169.5 4.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAK64215.1 - 3.4e-20 72.1 0.0 1e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 GAK64215.1 - 1.4e-08 34.8 0.0 3.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 GAK64215.1 - 0.0019 18.5 0.1 0.016 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAK64215.1 - 0.032 13.7 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3337 PF11816.3 GAK64216.1 - 1.3e-78 264.7 0.0 3.9e-77 259.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) Carb_kinase PF01256.12 GAK64216.1 - 1.1e-47 162.3 0.0 4.2e-47 160.4 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate kinase WD40 PF00400.27 GAK64216.1 - 1.8e-26 90.9 32.3 7.1e-09 35.2 0.1 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat EOS1 PF12326.3 GAK64217.1 - 1.3e-17 63.8 0.0 3.5e-17 62.4 0.0 1.7 1 1 0 1 1 1 1 N-glycosylation protein Mito_carr PF00153.22 GAK64218.1 - 1.5e-71 236.1 1.0 1.7e-25 88.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 GAK64219.1 - 3.2e-20 72.1 14.6 6.4e-15 54.7 5.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK64219.1 - 0.0025 16.4 4.3 0.0025 16.4 3.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRAPPC10 PF12584.3 GAK64220.1 - 1.2e-21 76.7 0.1 2e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DNA_ligase_A_M PF01068.16 GAK64221.1 - 1.2e-56 191.2 0.0 2e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAK64221.1 - 6.3e-53 179.2 0.2 9.9e-53 178.5 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAK64221.1 - 3e-24 85.2 0.0 7.9e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 GAK64221.1 - 0.026 14.2 0.2 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain eIF-3c_N PF05470.7 GAK64221.1 - 0.043 11.9 0.1 0.065 11.3 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pkinase PF00069.20 GAK64222.1 - 3.8e-70 236.0 0.3 7.2e-69 231.8 0.2 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64222.1 - 2.5e-36 125.0 0.1 1.5e-33 115.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 GAK64222.1 - 8.7e-18 63.5 0.3 8.7e-18 63.5 0.2 1.7 2 0 0 2 2 2 1 Kinase associated domain 1 Kdo PF06293.9 GAK64222.1 - 1.1e-05 24.5 0.1 3.6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAK64222.1 - 0.00018 20.6 1.3 0.00042 19.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like CAF-1_p150 PF11600.3 GAK64222.1 - 0.0015 17.9 31.4 0.0015 17.9 21.7 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal WaaY PF06176.6 GAK64222.1 - 0.098 11.8 0.3 0.16 11.2 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Spore_coat_CotO PF14153.1 GAK64222.1 - 1.1 8.6 13.7 2.3 7.6 9.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Seadorna_VP7 PF07387.6 GAK64222.1 - 1.3 7.7 0.0 2.1 7.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ycf1 PF05758.7 GAK64222.1 - 5.9 4.4 6.8 8.1 4.0 4.7 1.1 1 0 0 1 1 1 0 Ycf1 AAA_2 PF07724.9 GAK64223.1 - 1.2e-33 116.4 0.0 5.1e-33 114.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAK64223.1 - 7.8e-13 48.7 0.0 1.6e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK64223.1 - 2.3e-07 30.9 0.0 7.3e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAK64223.1 - 2.7e-06 27.5 0.0 9.8e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK64223.1 - 3.9e-05 24.4 0.0 7.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAK64223.1 - 4.6e-05 23.1 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.18 GAK64223.1 - 4.7e-05 22.3 0.0 8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family ClpB_D2-small PF10431.4 GAK64223.1 - 8.9e-05 22.3 0.0 0.54 10.2 0.0 2.5 2 0 0 2 2 2 2 C-terminal, D2-small domain, of ClpB protein AAA_33 PF13671.1 GAK64223.1 - 0.00026 20.8 0.1 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 GAK64223.1 - 0.0034 17.6 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 GAK64223.1 - 0.0044 16.5 0.1 0.0097 15.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 GAK64223.1 - 0.0048 16.7 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAK64223.1 - 0.0065 16.1 0.1 0.021 14.5 0.0 1.8 1 1 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 GAK64223.1 - 0.018 14.4 0.0 0.28 10.5 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 GAK64223.1 - 0.019 14.4 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 GAK64223.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAK64223.1 - 0.027 13.6 0.0 0.17 11.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAK64223.1 - 0.034 14.4 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAK64223.1 - 0.037 13.7 1.3 0.19 11.5 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 GAK64223.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 GAK64223.1 - 0.044 13.7 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAK64223.1 - 0.049 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 GAK64223.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.6 GAK64223.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAK64223.1 - 0.075 12.4 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain G-alpha PF00503.15 GAK64223.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.5 GAK64223.1 - 0.16 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.7 GAK64223.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Pirin PF02678.11 GAK64224.1 - 2.2e-29 101.4 1.1 5.2e-29 100.2 0.4 1.8 2 0 0 2 2 2 1 Pirin Cupin_2 PF07883.6 GAK64224.1 - 1.2e-09 37.4 0.7 3.8e-08 32.7 0.2 2.6 2 0 0 2 2 2 1 Cupin domain SMC_N PF02463.14 GAK64225.1 - 3.8e-67 225.7 0.0 1.1e-66 224.2 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAK64225.1 - 2.3e-22 79.2 1.2 7e-22 77.6 0.3 2.4 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAK64225.1 - 7.6e-13 49.0 7.8 4.6e-06 26.7 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 GAK64225.1 - 1.9e-06 28.3 38.2 1.9e-06 28.3 26.5 5.6 2 2 0 2 2 1 1 AAA domain AAA_29 PF13555.1 GAK64225.1 - 8.5e-05 21.9 0.1 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Spc7 PF08317.6 GAK64225.1 - 0.00021 20.0 31.8 0.00055 18.7 12.1 7.0 2 2 3 6 6 6 3 Spc7 kinetochore protein Reo_sigmaC PF04582.7 GAK64225.1 - 0.00025 20.3 24.5 0.0019 17.4 0.3 5.5 3 2 4 7 7 7 3 Reovirus sigma C capsid protein AAA_15 PF13175.1 GAK64225.1 - 0.00047 19.3 8.3 0.00047 19.3 5.7 1.9 2 0 0 2 2 2 1 AAA ATPase domain IncA PF04156.9 GAK64225.1 - 0.0011 18.6 8.6 0.0011 18.6 5.9 6.9 4 2 2 6 6 6 2 IncA protein Filament PF00038.16 GAK64225.1 - 0.0018 17.8 73.3 0.041 13.3 0.8 7.2 2 2 4 7 7 7 4 Intermediate filament protein GAS PF13851.1 GAK64225.1 - 0.0032 16.7 3.7 0.0032 16.7 2.6 6.9 3 2 4 7 7 7 2 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 GAK64225.1 - 0.0075 14.7 74.9 0.15 10.5 15.8 5.8 3 2 2 5 5 5 3 AAA domain DUF4200 PF13863.1 GAK64225.1 - 0.0097 15.8 6.3 0.0097 15.8 4.3 8.5 6 3 1 8 8 6 1 Domain of unknown function (DUF4200) ABC_tran PF00005.22 GAK64225.1 - 0.033 14.4 0.0 0.033 14.4 0.0 6.3 5 1 0 5 5 5 0 ABC transporter Fez1 PF06818.10 GAK64225.1 - 7.3 6.5 79.9 0.2 11.6 12.9 6.0 2 2 2 4 4 4 0 Fez1 ThiF PF00899.16 GAK64226.1 - 3.6e-05 23.6 0.0 8.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 GAK64226.1 - 0.015 14.9 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 MoeZ/MoeB domain Actin PF00022.14 GAK64227.1 - 7.7e-44 149.6 0.0 4.5e-41 140.5 0.0 3.0 2 1 0 2 2 2 2 Actin Cpn10 PF00166.16 GAK64228.1 - 1.3e-25 89.1 0.0 1.5e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.19 GAK64229.1 - 2.1e-119 399.3 5.6 2.5e-119 399.0 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Surp PF01805.15 GAK64230.1 - 0.0053 16.3 0.0 0.0093 15.5 0.0 1.4 1 0 0 1 1 1 1 Surp module Mago_nashi PF02792.9 GAK64231.1 - 5.6e-76 253.0 0.2 6.3e-76 252.9 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3368 PF11848.3 GAK64231.1 - 0.037 13.5 0.1 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Tubulin PF00091.20 GAK64232.1 - 1.8e-70 237.1 0.0 2.7e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAK64232.1 - 1.1e-47 161.2 0.2 1.8e-47 160.5 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAK64232.1 - 1.2e-07 31.8 0.0 2.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAK64232.1 - 0.0017 17.8 0.0 0.0041 16.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain TPR_11 PF13414.1 GAK64233.1 - 1.6e-11 43.6 26.3 2.4e-06 27.1 0.8 6.2 6 1 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 GAK64233.1 - 8.1e-09 34.7 26.9 0.0035 17.1 0.2 7.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAK64233.1 - 1.7e-06 28.1 43.6 0.01 16.3 0.8 9.5 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAK64233.1 - 5.3e-06 26.2 10.2 0.023 14.8 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAK64233.1 - 1e-05 24.8 14.6 0.018 14.6 0.1 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK64233.1 - 2.1e-05 25.0 13.5 3.4e-05 24.3 2.1 8.2 6 4 1 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAK64233.1 - 0.00052 19.5 5.0 0.54 10.1 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAK64233.1 - 0.015 15.0 6.8 1.9 8.5 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.5 GAK64233.1 - 0.056 12.2 2.0 0.043 12.5 0.3 1.5 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 GAK64233.1 - 0.44 10.5 33.7 0.74 9.7 3.1 7.0 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAK64233.1 - 0.46 10.8 31.5 0.071 13.4 1.1 6.7 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAK64233.1 - 0.89 9.4 23.7 2.1 8.2 0.2 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 GAK64234.1 - 1.7e-75 253.5 0.0 2.3e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64234.1 - 8.3e-37 126.6 0.0 1.3e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK64234.1 - 1.5e-08 33.9 0.0 2.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-C4H2 PF10146.4 GAK64234.1 - 0.0019 18.2 1.4 0.0083 16.1 0.9 2.0 1 1 0 1 1 1 1 Zinc finger-containing protein RIO1 PF01163.17 GAK64234.1 - 0.004 16.5 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.6 GAK64234.1 - 0.013 15.7 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YukC PF10140.4 GAK64234.1 - 0.26 9.7 0.0 0.42 9.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Na_Ca_ex PF01699.19 GAK64235.1 - 4e-40 136.6 34.1 2.3e-22 79.0 6.1 3.0 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 GAK64235.1 - 0.0073 16.1 3.7 0.0081 16.0 0.2 2.7 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) 4_1_CTD PF05902.8 GAK64237.1 - 0.0096 15.9 0.3 4.5 7.3 0.0 2.3 2 0 0 2 2 2 2 4.1 protein C-terminal domain (CTD) ResIII PF04851.10 GAK64238.1 - 6e-20 71.8 0.0 1.5e-19 70.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAK64238.1 - 3.6e-14 52.3 0.0 1e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK64238.1 - 7.9e-14 51.4 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 GAK64238.1 - 0.00011 21.0 0.1 0.0014 17.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain T2SE PF00437.15 GAK64238.1 - 0.00057 18.8 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 GAK64238.1 - 0.0011 19.1 0.0 0.0051 16.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 GAK64238.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 GAK64238.1 - 0.015 14.3 0.0 0.043 12.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 GAK64238.1 - 0.026 14.0 0.8 1.8 8.1 0.0 3.2 2 2 0 3 3 3 0 AAA domain Spore_SspJ PF09575.5 GAK64238.1 - 0.21 11.8 1.2 2.5 8.3 0.3 2.7 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) CENP-K PF11802.3 GAK64239.1 - 1.1e-06 28.1 7.8 4.2e-06 26.1 0.0 2.5 1 1 1 2 2 2 1 Centromere-associated protein K FeoC PF09012.5 GAK64239.1 - 0.013 15.1 0.1 0.045 13.4 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator Zn_clus PF00172.13 GAK64240.1 - 7.3e-05 22.5 14.3 0.00011 22.0 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Saccharop_dh PF03435.13 GAK64244.1 - 3e-112 375.4 0.0 4.9e-112 374.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 GAK64244.1 - 2.9e-89 298.2 0.0 4.6e-89 297.5 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 GAK64244.1 - 0.0019 18.5 0.1 0.0095 16.2 0.0 2.3 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAK64244.1 - 0.0049 15.5 0.0 0.0082 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAK64244.1 - 0.026 14.5 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Methyltransf_12 PF08242.7 GAK64244.1 - 0.033 14.6 0.1 0.47 10.9 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain Shikimate_DH PF01488.15 GAK64244.1 - 0.039 14.0 1.0 0.29 11.2 0.1 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF2325 PF10087.4 GAK64244.1 - 0.23 11.2 1.1 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) TAFII28 PF04719.9 GAK64245.1 - 3.6e-21 74.7 0.2 7.3e-17 60.9 0.0 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region AMP-binding PF00501.23 GAK64246.1 - 9e-80 268.0 0.0 1.1e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK64246.1 - 3.7e-11 43.8 0.0 8.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SKN1 PF03935.10 GAK64247.1 - 1.3e-182 607.4 0.2 1.6e-182 607.2 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Herpeto_peptide PF14409.1 GAK64247.1 - 0.065 13.0 0.2 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Herpetosiphon Rot1 PF10681.4 GAK64249.1 - 1.1e-60 204.5 0.2 1.4e-60 204.2 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal SKN1 PF03935.10 GAK64250.1 - 4.9e-189 628.6 5.1 5.7e-189 628.4 3.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 GAK64251.1 - 8.4e-181 601.4 1.6 1.1e-180 601.1 1.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GTP_EFTU PF00009.22 GAK64252.1 - 4.7e-56 189.2 0.1 8.9e-56 188.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAK64252.1 - 1.7e-34 117.9 0.1 5.4e-34 116.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 GAK64252.1 - 8.8e-31 105.5 0.0 2.3e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 GAK64252.1 - 5.7e-22 77.3 0.1 1.6e-21 75.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAK64252.1 - 5.5e-13 48.8 0.0 1.5e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 adh_short_C2 PF13561.1 GAK64252.1 - 0.01 15.6 0.3 0.022 14.5 0.2 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-C2H2 PF00096.21 GAK64253.1 - 2.4e-05 24.4 13.5 0.002 18.3 2.4 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK64253.1 - 0.0013 18.8 3.2 0.0013 18.8 2.2 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAK64253.1 - 0.0018 18.4 16.9 0.0098 16.1 1.7 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger Fer2 PF00111.22 GAK64254.1 - 1.2e-05 24.9 1.2 1.2e-05 24.9 0.8 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_12 PF13353.1 GAK64255.1 - 0.00016 21.8 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAK64255.1 - 0.00042 20.3 0.0 0.00087 19.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 GAK64255.1 - 0.033 14.3 0.0 0.087 12.9 0.0 1.8 1 1 0 1 1 1 0 Radical SAM superfamily Cu-oxidase_3 PF07732.10 GAK64256.1 - 4.2e-40 136.1 5.2 6.2e-39 132.3 1.2 3.5 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 GAK64256.1 - 5.8e-34 117.2 0.1 8.4e-33 113.5 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAK64256.1 - 6.7e-34 116.3 8.9 2.2e-30 104.9 0.2 4.2 3 1 0 3 3 3 2 Multicopper oxidase SpoIIE PF07228.7 GAK64257.1 - 1.2e-06 28.3 0.5 0.11 12.1 0.1 3.5 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 GAK64257.1 - 1.5e-05 24.5 0.1 0.00019 20.8 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 GAK64257.1 - 0.00022 20.6 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Fungal_trans PF04082.13 GAK64259.1 - 2.3e-40 138.1 0.1 3.7e-40 137.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAK64259.1 - 5.3e-08 32.7 10.6 0.0015 18.7 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK64259.1 - 0.00056 20.0 12.4 0.057 13.7 1.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAK64259.1 - 0.11 12.4 0.4 0.34 10.8 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAK64259.1 - 0.28 11.5 5.3 0.21 11.9 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain NOA36 PF06524.7 GAK64259.1 - 8.5 5.5 9.3 15 4.7 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein Peptidase_M48 PF01435.13 GAK64260.1 - 2.5e-39 135.1 0.1 5.7e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 GAK64260.1 - 0.013 14.5 0.0 0.013 14.5 0.0 2.9 4 0 0 4 4 4 0 BlaR1 peptidase M56 Peptidase_MA_2 PF13485.1 GAK64260.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily SprT-like PF10263.4 GAK64260.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M43 PF05572.8 GAK64260.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A FA_desaturase PF00487.19 GAK64261.1 - 1.4 8.2 8.9 0.95 8.8 5.3 1.3 1 1 0 1 1 1 0 Fatty acid desaturase PepSY_TM_2 PF13703.1 GAK64261.1 - 3.2 7.9 8.6 0.39 10.9 1.0 2.6 3 1 0 3 3 3 0 PepSY-associated TM helix DUF4246 PF14033.1 GAK64262.1 - 4.5e-181 602.8 0.0 5.7e-181 602.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 GAK64262.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF4066 PF13278.1 GAK64263.1 - 1.8e-28 98.9 0.5 2.6e-28 98.3 0.3 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAK64263.1 - 1.1e-15 57.3 0.1 1.6e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Abhydrolase_6 PF12697.2 GAK64264.1 - 2.6e-09 37.3 0.9 1.8e-08 34.5 0.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF333 PF03891.10 GAK64266.1 - 5.4e-23 80.5 0.0 8.7e-23 79.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF333) DUF3712 PF12505.3 GAK64267.1 - 3.7e-89 295.1 33.5 2.1e-15 56.8 0.0 9.9 11 1 1 12 12 12 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 GAK64267.1 - 3.9e-08 33.5 25.4 0.14 12.5 0.0 10.2 11 0 0 11 11 11 4 Late embryogenesis abundant protein GCR1_C PF12550.3 GAK64268.1 - 6.4e-18 64.3 0.0 1.2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes GMC_oxred_N PF00732.14 GAK64269.1 - 1.6e-60 204.7 0.0 2.1e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK64269.1 - 5.5e-34 117.5 0.0 9.5e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAK64269.1 - 5.4e-05 22.2 0.0 0.14 10.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAK64269.1 - 9.9e-05 21.4 0.2 0.0021 17.0 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK64269.1 - 0.0014 18.5 0.0 0.0035 17.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAK64269.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Fe_hyd_lg_C PF02906.9 GAK64270.1 - 6.6e-69 232.3 0.0 1.2e-68 231.4 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain ELFV_dehydrog PF00208.16 GAK64271.1 - 1.6e-80 270.2 2.1 2.3e-80 269.7 1.4 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 GAK64271.1 - 4.1e-44 149.3 0.0 7.4e-44 148.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 GAK64271.1 - 0.061 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding B12D PF06522.6 GAK64272.1 - 1.1e-18 66.7 0.1 1.4e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PS_Dcarbxylase PF02666.10 GAK64273.1 - 9.1e-50 168.7 0.0 1.7e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 GAK64273.1 - 1.1e-32 111.6 0.2 7.3e-14 51.3 0.0 3.7 3 0 0 3 3 3 3 C2 domain EF-hand_7 PF13499.1 GAK64273.1 - 6.7e-07 29.3 0.6 1.5e-06 28.2 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 GAK64273.1 - 0.00097 18.3 0.3 0.0056 15.9 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 GAK64273.1 - 0.0058 16.4 7.6 0.33 10.9 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain Daxx PF03344.10 GAK64273.1 - 0.025 13.1 1.4 0.04 12.4 1.0 1.2 1 0 0 1 1 1 0 Daxx Family CEP76-C2 PF15627.1 GAK64273.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain SDA1 PF05285.7 GAK64273.1 - 1.3 8.2 6.1 2 7.5 4.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 GAK64273.1 - 3.5 5.4 9.2 5.2 4.8 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 GAK64273.1 - 6.5 5.7 9.9 11 4.9 6.9 1.3 1 0 0 1 1 1 0 BUD22 DUF1764 PF08576.5 GAK64274.1 - 4.3e-14 53.1 16.1 1.9e-13 51.0 0.3 2.3 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) MIP-T3 PF10243.4 GAK64274.1 - 0.013 14.0 7.8 0.013 13.9 5.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 KAR9 PF08580.5 GAK64274.1 - 0.49 8.5 18.0 0.55 8.4 12.5 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ndc1_Nup PF09531.5 GAK64274.1 - 0.51 8.6 5.5 0.52 8.6 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4614 PF15391.1 GAK64274.1 - 2.1 8.0 15.9 3.2 7.4 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF566 PF04484.7 GAK64274.1 - 2.3 7.6 23.2 3.3 7.1 16.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2201_N PF13203.1 GAK64274.1 - 6 5.9 10.0 8.3 5.4 6.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Presenilin PF01080.12 GAK64274.1 - 6.2 5.5 9.5 7.4 5.2 6.6 1.1 1 0 0 1 1 1 0 Presenilin TPR_11 PF13414.1 GAK64275.1 - 5.2e-11 42.0 1.7 1.7e-08 34.0 1.4 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 GAK64275.1 - 3e-08 32.9 1.6 1.6e-05 24.3 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAK64275.1 - 9.6e-08 31.3 3.4 6.6e-05 22.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK64275.1 - 4.7e-06 27.1 6.5 1.1e-05 25.9 4.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAK64275.1 - 0.00011 22.5 6.5 0.0013 19.0 1.9 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAK64275.1 - 0.00012 21.9 3.8 0.00024 20.9 1.4 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAK64275.1 - 0.00056 20.0 0.1 0.0015 18.6 0.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAK64275.1 - 0.0031 18.0 5.3 0.0063 17.0 0.6 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAK64275.1 - 0.0046 16.7 2.2 0.0085 15.9 1.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAK64275.1 - 0.0072 16.7 7.3 0.094 13.2 0.2 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAK64275.1 - 0.0076 15.9 0.5 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAK64275.1 - 0.027 14.6 4.6 0.37 11.1 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAK64275.1 - 0.035 14.0 2.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAK64275.1 - 0.041 14.3 0.4 0.42 11.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAK64275.1 - 0.24 11.2 1.9 1.9 8.4 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC2_membrane PF01061.19 GAK64276.1 - 2e-74 249.3 78.2 1.5e-39 135.3 21.6 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAK64276.1 - 5.4e-36 123.8 0.0 1.6e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAK64276.1 - 2e-29 101.2 0.0 5.5e-24 83.8 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 GAK64276.1 - 2.6e-07 30.6 0.0 5.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_22 PF13401.1 GAK64276.1 - 7.7e-06 26.0 0.0 0.16 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAK64276.1 - 9.1e-06 25.1 0.8 0.0052 16.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAK64276.1 - 1.3e-05 24.4 0.5 0.0024 17.0 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 GAK64276.1 - 3.4e-05 23.0 59.2 0.0059 15.6 17.1 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 GAK64276.1 - 0.00012 22.1 0.0 0.22 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain cobW PF02492.14 GAK64276.1 - 0.00015 21.2 0.1 0.0081 15.6 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 GAK64276.1 - 0.00015 22.5 0.0 0.59 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAK64276.1 - 0.00031 20.6 0.1 1.2 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAK64276.1 - 0.0004 19.6 0.0 0.0059 15.8 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAK64276.1 - 0.00043 19.7 0.2 0.044 13.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAK64276.1 - 0.00087 18.8 0.1 0.36 10.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 GAK64276.1 - 0.0051 16.4 0.0 2.6 7.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 GAK64276.1 - 0.0061 16.5 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAK64276.1 - 0.007 16.6 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF3357 PF11837.3 GAK64276.1 - 0.019 14.8 0.1 0.08 12.7 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF3357) TMEM191C PF15194.1 GAK64276.1 - 0.031 14.1 0.1 0.099 12.5 0.1 1.8 1 0 0 1 1 1 0 TMEM191C family AAA_28 PF13521.1 GAK64276.1 - 0.043 13.7 0.2 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAK64276.1 - 0.059 13.3 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 GAK64276.1 - 0.078 13.4 0.1 8.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 GAK64276.1 - 0.093 12.9 0.0 17 5.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 GAK64276.1 - 0.096 12.3 0.5 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 GAK64276.1 - 0.11 11.3 0.5 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 GAK64276.1 - 0.17 12.0 0.0 29 4.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.4 GAK64276.1 - 0.26 10.7 0.7 1.2 8.6 0.2 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF221 PF02714.10 GAK64277.1 - 2.8e-42 144.7 21.0 4.1e-42 144.1 14.5 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAK64277.1 - 1.7e-15 56.8 1.9 1.7e-15 56.8 1.3 3.0 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAK64277.1 - 0.0032 17.9 0.2 0.13 12.8 0.1 3.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 GAK64277.1 - 0.014 15.4 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ALIX_LYPXL_bnd PF13949.1 GAK64277.1 - 0.056 12.3 0.4 0.098 11.6 0.3 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PALP PF00291.20 GAK64279.1 - 3.3e-53 180.8 0.0 2e-35 122.4 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme AA_permease_2 PF13520.1 GAK64280.1 - 2.3e-52 177.9 46.2 2.8e-52 177.6 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAK64280.1 - 2.8e-20 72.1 47.4 4.9e-20 71.3 32.8 1.3 1 1 0 1 1 1 1 Amino acid permease ADH_N PF08240.7 GAK64281.1 - 7e-30 103.0 0.2 1.5e-29 101.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK64281.1 - 1.9e-25 88.8 0.6 3e-25 88.2 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CPSF_A PF03178.10 GAK64282.1 - 3.8e-42 144.5 0.0 7.6e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 GAK64282.1 - 2.5e-27 95.1 0.0 4.5e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Trs65 PF12735.2 GAK64283.1 - 2.6e-05 23.6 0.0 0.0048 16.2 0.0 2.4 2 0 0 2 2 2 2 TRAPP trafficking subunit Trs65 Aminotran_4 PF01063.14 GAK64284.1 - 9.2e-17 61.2 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV vATP-synt_AC39 PF01992.11 GAK64285.1 - 8.4e-99 330.8 0.0 9.4e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Fungal_trans PF04082.13 GAK64286.1 - 1.4e-05 24.0 0.0 3.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK64286.1 - 2.5e-05 24.1 9.2 5.8e-05 22.9 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3681 PF12442.3 GAK64286.1 - 0.019 15.1 5.1 0.067 13.3 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) SEN1_N PF12726.2 GAK64287.1 - 1.7e-125 419.7 0.8 2.1e-125 419.4 0.6 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 GAK64287.1 - 3.5e-67 226.4 0.1 8.7e-67 225.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 GAK64287.1 - 1.3e-61 207.4 0.0 2.8e-61 206.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAK64287.1 - 1.7e-12 46.9 0.5 8.5e-12 44.6 0.3 2.3 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 GAK64287.1 - 7.7e-05 22.3 0.6 0.35 10.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 GAK64287.1 - 0.0027 17.1 0.1 0.0078 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 GAK64287.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 GAK64287.1 - 0.27 11.3 2.3 6.2 6.9 0.1 3.5 4 0 0 4 4 4 0 AAA domain AAA PF00004.24 GAK64287.1 - 0.41 10.8 1.6 1.8 8.7 1.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IDO PF01231.13 GAK64288.1 - 5.7e-06 25.0 0.0 0.0015 17.0 0.0 2.5 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase Sugar_tr PF00083.19 GAK64292.1 - 8.2e-27 93.8 32.2 4.1e-17 61.9 11.8 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAK64292.1 - 1.4e-16 60.1 36.3 1.3e-10 40.5 10.5 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily BT1 PF03092.11 GAK64292.1 - 0.021 13.5 11.3 0.33 9.6 0.1 2.9 2 2 0 2 2 2 0 BT1 family WTF PF03303.8 GAK64292.1 - 0.12 11.7 0.1 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 WTF protein Aldo_ket_red PF00248.16 GAK64294.1 - 7.9e-60 202.0 0.0 1.2e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Transket_pyr PF02779.19 GAK64294.1 - 4.5e-41 140.3 0.5 6.2e-40 136.5 0.0 2.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAK64294.1 - 1.6e-29 102.3 0.0 5.4e-29 100.6 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Ribosomal_L10 PF00466.15 GAK64294.1 - 4.1e-06 26.6 0.0 9.4e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 WD40 PF00400.27 GAK64295.1 - 8.3e-36 120.5 16.2 3.6e-09 36.1 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAK64295.1 - 8.6e-05 22.3 0.0 0.026 14.2 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAK64295.1 - 0.00066 17.9 1.4 0.00098 17.3 1.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 IKI3 PF04762.7 GAK64295.1 - 0.073 10.8 0.0 0.75 7.5 0.0 2.1 1 1 1 2 2 2 0 IKI3 family NDK PF00334.14 GAK64296.1 - 4e-57 191.7 0.0 4.9e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 GAK64296.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ NDT80_PhoG PF05224.7 GAK64297.1 - 1.9e-16 60.5 0.0 3.2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AOX PF01786.12 GAK64298.1 - 3.4e-93 310.7 0.3 4.2e-93 310.4 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Ribosomal_L34e PF01199.13 GAK64299.1 - 2.4e-35 120.5 6.1 6e-35 119.3 4.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L34e Gemini_C4 PF01492.12 GAK64299.1 - 0.19 11.4 3.1 2.6 7.8 0.2 2.9 3 0 0 3 3 3 0 Geminivirus C4 protein Ribosomal_L6 PF00347.18 GAK64300.1 - 3.4e-22 78.7 0.5 6.9e-14 52.1 0.0 3.7 3 1 0 3 3 3 2 Ribosomal protein L6 R3H-assoc PF13902.1 GAK64301.1 - 0.0018 18.2 0.3 0.0018 18.2 0.2 2.5 2 1 1 3 3 3 1 R3H-associated N-terminal domain DUF605 PF04652.11 GAK64303.1 - 0.2 10.9 16.3 0.25 10.7 11.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF953 PF06110.6 GAK64304.1 - 2e-15 56.3 0.0 2.2e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 GAK64304.1 - 7.6e-05 22.3 0.0 8.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 GAK64304.1 - 0.027 14.0 0.4 0.042 13.4 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin UDG PF03167.14 GAK64305.1 - 3.3e-22 78.5 0.0 1.2e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Aldedh PF00171.17 GAK64306.1 - 4e-184 612.2 0.4 4.5e-184 612.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK64306.1 - 2.2e-05 23.3 0.0 3.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 GAK64306.1 - 0.039 13.1 0.0 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Fungal_trans_2 PF11951.3 GAK64307.1 - 5.5e-14 51.5 0.0 9.9e-14 50.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK64307.1 - 0.00029 20.6 12.0 0.00068 19.4 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.10 GAK64308.1 - 2.4e-100 336.7 42.5 4.5e-100 335.9 29.5 1.4 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DNase_NucA_NucB PF14040.1 GAK64309.1 - 2.2e-29 101.8 1.8 2.9e-29 101.5 1.3 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Me-amine-dh_L PF02975.9 GAK64309.1 - 0.0067 16.3 3.3 0.0067 16.3 2.3 1.9 1 1 1 2 2 2 1 Methylamine dehydrogenase, L chain ADH_N PF08240.7 GAK64310.1 - 3.7e-23 81.3 0.3 6.2e-23 80.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK64310.1 - 1.4e-14 53.7 0.0 2.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase XdhC_C PF13478.1 GAK64310.1 - 0.035 14.4 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 GAK64310.1 - 0.036 13.2 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAK64310.1 - 0.08 12.5 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 GAK64310.1 - 0.09 13.6 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DNA_pol_E_B PF04042.11 GAK64311.1 - 1.2e-42 145.5 0.2 1.8e-42 144.9 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 GAK64311.1 - 0.022 14.6 0.1 0.071 12.9 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_18 PF00704.23 GAK64312.1 - 5.3e-11 42.5 1.1 7.7e-11 42.0 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Phage_CI_repr PF07022.8 GAK64312.1 - 0.077 13.0 0.0 0.096 12.7 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Zn_clus PF00172.13 GAK64313.1 - 5.1e-05 23.0 10.1 0.00011 22.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HbrB PF08539.6 GAK64315.1 - 1.8e-42 144.8 0.0 2.8e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 HbrB-like His_Phos_1 PF00300.17 GAK64315.1 - 8.3e-29 100.7 0.0 1.4e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ras PF00071.17 GAK64316.1 - 4.8e-20 71.5 0.0 6.1e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK64316.1 - 4.5e-11 43.2 0.1 1.2e-10 41.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Mg_chelatase PF01078.16 GAK64316.1 - 3.2e-05 23.1 0.1 5.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 GAK64316.1 - 5.1e-05 23.3 0.1 8.9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.21 GAK64316.1 - 0.00036 20.0 0.4 0.00072 19.0 0.2 1.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 GAK64316.1 - 0.00094 19.3 0.1 0.0026 17.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 GAK64316.1 - 0.011 15.4 0.1 0.05 13.2 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 GAK64316.1 - 0.011 14.8 0.9 0.022 13.8 0.2 1.8 2 0 0 2 2 2 0 Zeta toxin Arf PF00025.16 GAK64316.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family KAP_NTPase PF07693.9 GAK64316.1 - 0.015 14.3 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain UPF0079 PF02367.12 GAK64316.1 - 0.016 14.8 0.1 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Gtr1_RagA PF04670.7 GAK64316.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAK64316.1 - 0.023 13.3 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.4 GAK64316.1 - 0.046 13.2 0.2 0.25 10.7 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 GAK64316.1 - 0.058 12.9 0.2 0.39 10.2 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAK64316.1 - 0.072 13.9 0.1 0.14 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAK64316.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 GAK64316.1 - 0.083 12.6 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 GAK64316.1 - 0.09 11.9 0.4 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 GAK64316.1 - 0.091 13.0 0.4 0.21 11.9 0.1 1.7 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.1 GAK64316.1 - 0.11 12.1 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Caleosin PF05042.8 GAK64317.1 - 9.9e-46 155.4 0.0 1.4e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Caleosin related protein Pkinase PF00069.20 GAK64319.1 - 5.7e-20 71.5 0.0 3e-18 65.8 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64319.1 - 2.8e-07 29.9 0.0 9.4e-07 28.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAK64319.1 - 0.00027 20.7 0.6 0.00058 19.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAK64319.1 - 0.0076 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 GAK64319.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAK64319.1 - 0.055 12.8 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 RIO1 family WaaY PF06176.6 GAK64319.1 - 0.33 10.1 0.1 0.7 9.0 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) SCHIP-1 PF10148.4 GAK64320.1 - 0.0017 17.8 2.3 0.0047 16.3 1.6 1.7 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 Inositol_P PF00459.20 GAK64321.1 - 1.9e-64 217.6 0.2 2.3e-64 217.3 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family HLH PF00010.21 GAK64322.1 - 7.6e-09 35.1 0.4 2.4e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Topoisom_bac PF01131.15 GAK64324.1 - 2.9e-90 303.0 0.0 3.5e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 GAK64324.1 - 7.9e-24 83.3 9.4 1.2e-13 50.7 0.6 2.7 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.17 GAK64324.1 - 6.2e-19 67.8 0.0 9.7e-18 63.9 0.0 2.5 2 1 0 2 2 2 1 Toprim domain zf-CCHC PF00098.18 GAK64324.1 - 4.7e-13 48.3 15.7 8.3e-07 28.6 2.0 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 GAK64324.1 - 2.6e-07 30.2 8.1 0.00067 19.3 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.1 GAK64324.1 - 7.5e-06 25.3 10.3 0.0026 17.2 0.3 2.7 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 GAK64324.1 - 0.59 9.6 4.6 11 5.5 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 GAK64324.1 - 5.6 6.7 7.4 18 5.1 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle OPT PF03169.10 GAK64325.1 - 1.2e-146 489.7 15.1 1.4e-146 489.5 10.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ARL6IP6 PF15062.1 GAK64325.1 - 0.0095 15.8 0.0 0.074 12.9 0.0 2.4 2 0 0 2 2 2 1 Haemopoietic lineage transmembrane helix DUF3995 PF13160.1 GAK64325.1 - 0.023 14.7 0.7 0.023 14.7 0.5 4.5 5 1 1 6 6 6 0 Protein of unknown function (DUF3995) Lysis_S PF04971.7 GAK64325.1 - 5.5 6.7 7.9 13 5.6 0.2 3.4 2 1 1 3 3 3 0 Lysis protein S PALP PF00291.20 GAK64326.1 - 8.3e-29 100.7 0.0 3.6e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 GAK64326.1 - 0.00054 20.2 0.2 0.013 15.7 0.1 2.6 1 1 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 GAK64327.1 - 7.7e-55 185.8 0.2 2.5e-35 121.9 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64327.1 - 3.3e-24 85.3 0.3 1.1e-16 60.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK64327.1 - 0.0073 15.3 0.0 0.035 13.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PAP2 PF01569.16 GAK64327.1 - 0.073 12.7 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 PAP2 superfamily Glyco_hydro_31 PF01055.21 GAK64328.1 - 2.6e-158 527.4 3.3 3.4e-158 527.1 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 HAMP PF00672.20 GAK64329.1 - 5.2e-47 157.9 19.8 2e-08 34.2 0.3 8.4 8 0 0 8 8 8 7 HAMP domain HATPase_c PF02518.21 GAK64329.1 - 1.7e-27 95.3 0.1 6.1e-27 93.5 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAK64329.1 - 2e-26 92.1 0.9 2.3e-24 85.5 0.4 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAK64329.1 - 5.6e-17 61.4 0.3 3.9e-16 58.8 0.2 2.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 GAK64329.1 - 0.023 14.4 0.1 0.42 10.5 0.0 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF2365 PF10157.4 GAK64329.1 - 0.15 11.9 10.7 45 3.8 0.1 6.4 6 2 1 7 7 7 0 Uncharacterized conserved protein (DUF2365) Syntaxin PF00804.20 GAK64329.1 - 0.68 10.1 8.7 10 6.3 0.7 5.1 4 2 0 4 4 4 0 Syntaxin Yippee-Mis18 PF03226.9 GAK64331.1 - 1.6e-15 56.8 0.1 3.2e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SKG6 PF08693.5 GAK64331.1 - 3.3e-06 26.3 0.1 7.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain WD40 PF00400.27 GAK64332.1 - 7.1e-19 66.9 1.3 0.0064 16.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 GAK64332.1 - 2.6e-13 49.7 0.0 4.8e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Metallophos PF00149.23 GAK64332.1 - 8.8e-08 31.7 2.7 2.4e-07 30.3 1.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAK64332.1 - 3.9e-07 30.0 0.1 7.5e-06 25.8 0.1 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain CLTH PF10607.4 GAK64333.1 - 4.9e-18 65.2 0.0 1.2e-17 63.9 0.0 1.7 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 GAK64333.1 - 2.7e-17 62.2 0.7 5.4e-17 61.2 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAK64333.1 - 1.3e-05 24.9 0.5 2.7e-05 23.9 0.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAK64333.1 - 2.2e-05 24.0 0.8 3.7e-05 23.3 0.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAK64333.1 - 0.0003 20.5 0.7 0.00049 19.8 0.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAK64333.1 - 0.00046 19.8 0.6 0.00074 19.1 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK64333.1 - 0.00085 19.2 1.4 0.0014 18.5 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK64333.1 - 0.0037 16.8 1.2 0.0064 16.1 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 GAK64333.1 - 0.12 11.8 0.3 0.24 10.9 0.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 GAK64333.1 - 0.21 11.1 1.1 0.35 10.4 0.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sec16_C PF12931.2 GAK64334.1 - 2.3e-82 276.9 0.0 3.2e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 GAK64334.1 - 9.4e-34 115.9 0.0 2e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region XPA_C PF05181.7 GAK64335.1 - 1.5e-26 91.7 2.0 2.5e-26 91.0 1.4 1.4 1 0 0 1 1 1 1 XPA protein C-terminus DUF1451 PF07295.6 GAK64335.1 - 0.12 12.1 6.2 0.25 11.1 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1451) A2L_zn_ribbon PF08792.5 GAK64335.1 - 0.21 11.1 1.9 0.38 10.2 0.2 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DZR PF12773.2 GAK64335.1 - 0.22 11.3 3.9 15 5.4 0.0 2.7 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 GAK64335.1 - 0.45 10.2 5.3 8.6 6.1 0.1 3.3 3 0 0 3 3 3 0 Nudix N-terminal YhzD PF14120.1 GAK64335.1 - 2 8.4 4.4 0.7 9.8 0.2 2.4 3 0 0 3 3 3 0 YhzD-like protein zinc_ribbon_2 PF13240.1 GAK64335.1 - 2 7.9 6.2 7.1 6.2 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 GAK64335.1 - 4.9 6.4 8.0 12 5.3 0.5 2.8 2 1 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 GAK64335.1 - 9.1 5.6 7.0 38 3.7 0.0 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding Glyco_hydro_63 PF03200.11 GAK64336.1 - 6.5e-231 768.4 0.0 4.9e-230 765.5 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 GAK64336.1 - 3.3e-07 29.3 0.1 5.7e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 GAK64336.1 - 2.5e-05 23.1 0.1 9.2e-05 21.3 0.0 1.8 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 GAK64336.1 - 0.0026 16.0 0.0 0.0043 15.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase SMI1_KNR4 PF09346.5 GAK64337.1 - 2.8e-30 105.0 0.0 4.7e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) zf-met2 PF12907.2 GAK64338.1 - 1.5e-14 53.6 0.9 2e-14 53.2 0.6 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 GAK64338.1 - 0.00068 20.3 11.8 0.00068 20.3 8.2 1.9 2 0 0 2 2 2 1 4F5 protein family Rep_fac-A_C PF08646.5 GAK64338.1 - 0.06 13.0 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain Gpi16 PF04113.9 GAK64340.1 - 4.9e-96 321.9 0.0 2.8e-49 167.6 0.0 3.4 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component FAD_binding_8 PF08022.7 GAK64341.1 - 1e-16 60.6 0.0 7.2e-16 57.9 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAK64341.1 - 8.1e-14 51.8 0.0 4.4e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAK64341.1 - 9.4e-12 45.1 9.4 9.4e-12 45.1 6.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Peptidase_A22B PF04258.8 GAK64342.1 - 2.3e-72 243.9 6.9 2.9e-72 243.6 4.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 GAK64342.1 - 7.7e-07 28.5 5.6 1.4e-06 27.6 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1119) CENP-B_dimeris PF09026.5 GAK64342.1 - 0.0011 19.1 1.5 0.0055 16.9 0.0 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.1 GAK64342.1 - 0.055 13.1 3.9 0.25 11.0 0.0 2.5 2 1 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 GAK64342.1 - 0.06 13.6 0.5 0.06 13.6 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1049 PF06305.6 GAK64342.1 - 0.1 12.1 0.0 0.1 12.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Nucleoplasmin PF03066.10 GAK64342.1 - 0.7 9.4 3.9 26 4.3 0.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin CTDII PF01556.13 GAK64343.1 - 1.9e-21 75.7 1.4 1.9e-19 69.2 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 GAK64343.1 - 5.5e-21 74.0 1.7 9.7e-21 73.2 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAK64343.1 - 5.6e-15 55.1 19.8 9.6e-15 54.3 13.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAK64343.1 - 0.038 13.6 11.0 0.28 10.8 2.3 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Glyco_hydro_25 PF01183.15 GAK64344.1 - 4.2e-44 150.5 0.3 4.8e-44 150.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 SIS PF01380.17 GAK64346.1 - 1.2e-17 63.7 0.0 2.7e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 GAK64346.1 - 6.5e-08 32.3 0.0 0.002 17.8 0.0 2.4 1 1 1 2 2 2 2 SIS domain CytochromB561_N PF09786.4 GAK64346.1 - 0.92 7.8 4.1 1.3 7.3 2.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MFS_1 PF07690.11 GAK64347.1 - 3.2e-41 141.2 35.6 3.2e-41 141.2 24.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OAD_gamma PF04277.8 GAK64347.1 - 7.3 7.0 10.8 0.32 11.4 0.1 3.5 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain YTH PF04146.10 GAK64348.1 - 4.2e-46 156.0 0.0 6.2e-46 155.4 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain PapG_N PF03627.8 GAK64348.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 PapG carbohydrate binding domain ThiF PF00899.16 GAK64350.1 - 1.1e-39 135.4 0.1 1.9e-39 134.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family RabGAP-TBC PF00566.13 GAK64350.1 - 7.2e-33 113.8 0.0 9.3e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MoeZ_MoeB PF05237.8 GAK64350.1 - 1.9e-23 81.8 0.1 4.6e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 GAK64350.1 - 5.3e-07 29.9 0.0 1.9e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 GAK64350.1 - 2.4e-05 24.4 0.0 4.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 GAK64350.1 - 0.068 12.1 0.5 0.12 11.2 0.4 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 GAK64350.1 - 0.081 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding TFIIIC_delta PF12657.2 GAK64351.1 - 3.3e-12 46.4 3.6 3.8e-12 46.2 0.1 2.5 3 0 0 3 3 3 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 GAK64351.1 - 2.8e-08 33.5 1.7 6.4e-08 32.4 1.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex GATase PF00117.23 GAK64351.1 - 0.0012 18.3 0.0 0.0037 16.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 GAK64351.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DnaJ-X PF14308.1 GAK64352.1 - 4.8e-58 195.8 0.8 4.8e-58 195.8 0.5 3.0 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 GAK64352.1 - 1.5e-19 69.4 0.3 1.5e-19 69.4 0.2 2.3 2 1 0 2 2 2 1 DnaJ domain FLO_LFY PF01698.11 GAK64352.1 - 0.12 11.2 10.7 0.25 10.1 7.4 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 GAK64352.1 - 0.58 10.4 11.1 0.3 11.4 5.6 2.0 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 GAK64353.1 - 9.9e-62 208.9 0.7 5.8e-49 166.9 0.1 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 GAK64353.1 - 1.4e-20 73.7 0.0 2.8e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAK64353.1 - 1.7e-08 34.6 0.5 8.7e-08 32.3 0.0 2.4 4 0 0 4 4 2 1 AAA domain UvrD_C_2 PF13538.1 GAK64353.1 - 2.1e-05 24.6 0.0 0.00089 19.3 0.0 2.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 GAK64353.1 - 2.5e-05 23.9 0.8 6.2e-05 22.6 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 GAK64353.1 - 3.2e-05 24.0 1.1 0.00018 21.5 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 GAK64353.1 - 0.00015 21.4 0.2 0.018 14.5 0.0 3.1 3 1 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 GAK64353.1 - 0.00036 20.7 0.3 0.001 19.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAK64353.1 - 0.0017 17.2 0.0 0.0036 16.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 GAK64353.1 - 0.0032 17.7 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter DUF2075 PF09848.4 GAK64353.1 - 0.0046 15.9 0.0 0.012 14.6 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 GAK64353.1 - 0.005 16.7 0.0 0.024 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 GAK64353.1 - 0.0052 15.4 0.0 0.0093 14.6 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 GAK64353.1 - 0.0084 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_32 PF13654.1 GAK64353.1 - 0.015 13.9 0.0 0.031 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 GAK64353.1 - 0.017 14.8 0.1 0.67 9.6 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 GAK64353.1 - 0.018 14.5 0.2 0.42 10.1 0.0 2.7 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 GAK64353.1 - 0.019 14.2 0.0 0.058 12.6 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Herpes_Helicase PF02689.9 GAK64353.1 - 0.022 12.5 0.1 0.15 9.7 0.0 2.0 2 0 0 2 2 2 0 Helicase Sigma54_activat PF00158.21 GAK64353.1 - 0.023 14.1 0.1 0.094 12.1 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAK64353.1 - 0.025 13.7 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAK64353.1 - 0.027 14.6 0.0 0.084 13.0 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 GAK64353.1 - 0.033 13.9 0.3 0.43 10.3 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 GAK64353.1 - 0.039 13.6 0.1 0.11 12.1 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 GAK64353.1 - 0.067 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 GAK64353.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAK64353.1 - 0.11 11.7 0.1 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 GAK64353.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UvrD-helicase PF00580.16 GAK64353.1 - 0.18 11.0 1.0 0.19 11.0 0.1 1.6 2 0 0 2 2 1 0 UvrD/REP helicase N-terminal domain Cys_Met_Meta_PP PF01053.15 GAK64354.1 - 2e-55 187.6 0.1 1.6e-46 158.3 0.1 2.7 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAK64354.1 - 0.0031 16.5 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.21 GAK64355.1 - 0.098 13.0 0.2 0.33 11.3 0.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2420 PF10336.4 GAK64357.1 - 2.2e-26 91.6 0.0 4.3e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Thiolase_N PF00108.18 GAK64358.1 - 1.3e-80 270.2 5.0 1.7e-80 269.7 3.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAK64358.1 - 1.7e-42 143.6 0.7 1.7e-42 143.6 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 GAK64358.1 - 0.0031 17.4 0.1 0.013 15.5 0.1 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 GAK64358.1 - 0.043 13.2 0.3 0.043 13.2 0.2 2.3 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Myosin_N PF02736.14 GAK64358.1 - 0.44 10.2 2.6 0.49 10.1 0.7 1.9 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Histone PF00125.19 GAK64359.1 - 2.8e-29 101.0 0.8 4.9e-29 100.2 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAK64359.1 - 6.4e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAK64359.1 - 0.0029 17.6 0.1 0.0069 16.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAK64359.1 - 0.036 13.8 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 GAK64360.1 - 8.6e-14 51.4 0.1 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAK64360.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 GAK64360.1 - 0.00024 20.9 0.1 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 GAK64360.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 GAK64360.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Reprolysin_5 PF13688.1 GAK64361.1 - 8.3e-43 146.6 9.1 8.3e-43 146.6 6.3 3.2 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 GAK64361.1 - 1.4e-37 129.4 6.3 4.9e-37 127.6 4.4 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Cyclin PF08613.6 GAK64361.1 - 1.8e-35 122.5 0.1 4e-21 75.9 0.0 3.4 2 0 0 2 2 2 2 Cyclin Reprolysin_4 PF13583.1 GAK64361.1 - 5.5e-35 120.7 2.0 1.3e-34 119.5 1.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAK64361.1 - 7.4e-19 68.4 0.3 3.5e-18 66.3 0.2 2.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 GAK64361.1 - 4e-14 52.5 25.5 4e-14 52.5 17.7 4.3 2 1 2 4 4 3 1 Disintegrin Reprolysin PF01421.14 GAK64361.1 - 5.6e-09 35.8 8.0 2.6e-07 30.4 5.6 2.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 GAK64361.1 - 5.8e-09 35.8 0.5 1.4e-08 34.5 0.4 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M43 PF05572.8 GAK64361.1 - 0.029 13.9 0.2 0.072 12.6 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A PgaD PF13994.1 GAK64361.1 - 0.17 11.3 0.2 0.41 10.1 0.2 1.6 1 0 0 1 1 1 0 PgaD-like protein EFG_C PF00679.19 GAK64361.1 - 0.19 11.6 0.0 0.51 10.2 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G C-terminus HMG_box PF00505.14 GAK64363.1 - 3.5e-12 46.4 2.2 6e-12 45.6 1.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAK64363.1 - 0.001 19.4 0.2 0.0021 18.3 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain DHC PF09626.5 GAK64363.1 - 0.0036 17.9 0.8 0.26 11.9 0.0 2.7 2 0 0 2 2 2 1 Dihaem cytochrome c Ribosomal_S4e PF00900.15 GAK64364.1 - 8.6e-31 105.4 0.2 1.9e-30 104.3 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 GAK64364.1 - 2.3e-07 30.5 0.0 6e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 GAK64364.1 - 0.00017 21.1 1.1 0.00066 19.2 0.8 2.1 1 0 0 1 1 1 1 KOW motif S4 PF01479.20 GAK64364.1 - 0.0008 18.7 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain MobB PF03205.9 GAK64367.1 - 0.39 10.4 2.4 48 3.6 0.0 3.1 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B MFS_1 PF07690.11 GAK64368.1 - 8e-10 37.9 24.2 8e-10 37.9 16.8 4.0 4 1 0 4 4 4 2 Major Facilitator Superfamily PAH PF02671.16 GAK64369.1 - 5e-44 147.6 3.1 7.4e-18 63.9 0.8 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 GAK64369.1 - 2e-39 133.4 0.1 5.5e-39 132.0 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Ribosomal_S21e PF01249.13 GAK64370.1 - 9.2e-34 115.2 0.0 1.5e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21e MFS_1 PF07690.11 GAK64371.1 - 2.5e-29 102.0 30.3 3.7e-29 101.5 21.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MARVEL PF01284.18 GAK64372.1 - 0.00013 21.8 19.9 0.016 14.9 5.0 3.1 1 1 2 3 3 3 3 Membrane-associating domain Yip1 PF04893.12 GAK64372.1 - 0.13 11.7 21.1 0.43 10.0 8.3 2.2 2 0 0 2 2 2 0 Yip1 domain YrhC PF14143.1 GAK64372.1 - 0.95 9.4 3.1 33 4.5 0.0 3.6 3 1 1 4 4 4 0 YrhC-like protein DUF4064 PF13273.1 GAK64372.1 - 2.9 8.0 12.5 2.8 8.0 0.2 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF4064) Cytochrom_C PF00034.16 GAK64373.1 - 8.6e-10 39.3 0.0 1.3e-09 38.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 GAK64373.1 - 4e-09 36.4 1.6 2.6e-08 33.8 1.1 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 GAK64373.1 - 2.3e-05 23.8 1.1 0.00021 20.7 0.1 2.2 2 1 0 2 2 2 1 Cytochrome c-550 domain VanZ PF04892.7 GAK64374.1 - 7e-10 38.9 0.6 1.8e-09 37.6 0.4 1.6 1 1 0 1 1 1 1 VanZ like family Rot1 PF10681.4 GAK64375.1 - 1.2e-55 188.1 1.7 1.4e-55 187.9 1.2 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF2040 PF09745.4 GAK64376.1 - 9.6e-36 122.4 19.9 9.6e-36 122.4 13.8 2.9 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Vps55 PF04133.9 GAK64377.1 - 1.3e-46 157.2 4.1 1.4e-46 157.0 2.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 zf-RING_4 PF14570.1 GAK64379.1 - 3.6e-21 74.4 11.5 6e-21 73.7 8.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 GAK64379.1 - 7.1e-06 25.5 8.2 1.2e-05 24.8 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 GAK64379.1 - 0.0011 18.7 0.0 0.0039 17.0 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK64379.1 - 0.0021 17.6 0.1 0.0088 15.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 GAK64379.1 - 0.01 15.8 12.1 0.017 15.1 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 GAK64379.1 - 0.018 14.7 3.6 0.041 13.6 2.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 GAK64379.1 - 0.64 9.7 11.5 1.1 8.9 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 GAK64379.1 - 1.5 8.5 9.8 0.48 10.1 4.4 1.8 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) LpxK PF02606.9 GAK64379.1 - 1.9 7.3 6.3 0.089 11.7 0.3 1.7 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase SRP54 PF00448.17 GAK64380.1 - 7.9e-76 253.8 0.2 1.5e-75 252.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 GAK64380.1 - 3.7e-21 75.3 0.2 3.7e-21 75.3 0.1 4.9 4 2 2 6 6 5 1 Signal peptide binding domain SRP54_N PF02881.14 GAK64380.1 - 8.1e-12 45.0 0.1 2.3e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 GAK64380.1 - 2.3e-06 27.5 0.0 6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 GAK64380.1 - 4.4e-06 26.2 0.1 1.5e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 GAK64380.1 - 0.00042 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 GAK64380.1 - 0.0011 18.9 0.2 0.032 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAK64380.1 - 0.0025 17.9 0.1 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 GAK64380.1 - 0.0027 17.6 0.0 0.26 11.2 0.0 2.5 1 1 0 2 2 2 1 AAA domain CbiA PF01656.18 GAK64380.1 - 0.004 16.5 0.2 0.016 14.6 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 GAK64380.1 - 0.0084 16.9 0.0 0.017 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 GAK64380.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase GTP_EFTU PF00009.22 GAK64380.1 - 0.052 12.9 0.1 0.18 11.2 0.1 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TrwB_AAD_bind PF10412.4 GAK64380.1 - 0.068 11.7 0.9 1.4 7.5 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain ArsA_ATPase PF02374.10 GAK64380.1 - 0.069 12.1 0.8 6.5 5.6 0.0 2.9 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_18 PF13238.1 GAK64380.1 - 0.078 13.2 0.0 0.19 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 GAK64380.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.12 GAK64380.1 - 0.099 12.1 0.7 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.5 GAK64380.1 - 0.11 11.7 0.3 3.1 6.9 0.1 2.4 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 GAK64380.1 - 0.17 11.8 0.2 0.52 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Peptidase_M13_N PF05649.8 GAK64382.1 - 1.6e-95 320.4 0.0 2.1e-95 320.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 GAK64382.1 - 5.2e-57 192.3 0.0 7.6e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_MA_2 PF13485.1 GAK64382.1 - 0.04 13.9 0.2 0.084 12.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Cyclin_N PF00134.18 GAK64384.1 - 4.5e-13 48.8 0.0 8.9e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAK64384.1 - 1.9e-11 44.5 0.0 4.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin CDC45 PF02724.9 GAK64384.1 - 0.018 13.1 6.7 0.025 12.6 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein FBPase PF00316.15 GAK64386.1 - 1e-127 425.4 0.0 1.2e-127 425.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 GAK64386.1 - 0.009 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family IncFII_repA PF02387.10 GAK64386.1 - 0.22 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 IncFII RepA protein family BTB PF00651.26 GAK64387.1 - 0.0063 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CwfJ_C_1 PF04677.10 GAK64388.1 - 3.4e-24 84.8 0.0 5.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 GAK64388.1 - 2.1e-09 37.7 0.3 1.4e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 Protein similar to CwfJ C-terminus 2 DUF4070 PF13282.1 GAK64388.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) Aconitase PF00330.15 GAK64389.1 - 1.2e-155 518.5 0.0 2.7e-155 517.4 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAK64389.1 - 1.3e-33 115.9 0.0 2.5e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.4 GAK64389.1 - 1.8e-06 27.8 1.5 0.00014 21.6 0.3 2.4 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 RdRP PF05183.7 GAK64390.1 - 1.6e-110 370.5 0.0 2.3e-110 370.0 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase SAP PF02037.22 GAK64391.1 - 7.8e-05 22.0 0.2 0.00017 21.0 0.2 1.6 1 0 0 1 1 1 1 SAP domain Polysacc_deac_1 PF01522.16 GAK64392.1 - 1.3e-28 99.0 0.0 3.7e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Serglycin PF04360.7 GAK64392.1 - 0.0072 16.0 1.8 0.017 14.8 1.3 1.6 1 0 0 1 1 1 1 Serglycin Macoilin PF09726.4 GAK64392.1 - 1.2 7.3 10.5 1.6 6.9 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 GAK64392.1 - 5 5.8 6.1 6.8 5.4 4.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zds_C PF08632.5 GAK64395.1 - 3.1e-21 74.5 1.1 8e-21 73.1 0.8 1.7 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Gti1_Pac2 PF09729.4 GAK64396.1 - 1.9e-45 154.7 0.2 8.8e-35 120.0 0.0 2.6 1 1 1 2 2 2 2 Gti1/Pac2 family Ran_BP1 PF00638.13 GAK64399.1 - 9.3e-18 64.4 1.2 1.8e-17 63.5 0.8 1.4 1 0 0 1 1 1 1 RanBP1 domain HAT PF02184.11 GAK64400.1 - 1.9e-17 62.6 58.5 7.3e-09 35.2 0.0 13.6 14 1 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 GAK64400.1 - 3.8e-13 48.7 46.3 0.00057 20.2 0.0 13.0 9 3 7 16 16 14 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAK64400.1 - 1.5e-11 44.4 8.3 0.0072 16.6 0.1 7.5 5 1 4 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAK64400.1 - 5.9e-10 38.3 17.0 0.011 15.5 0.1 9.4 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK64400.1 - 1.1e-09 38.7 24.8 0.00026 21.5 0.0 8.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAK64400.1 - 1.7e-08 33.9 8.8 0.011 15.3 0.0 7.3 5 3 4 9 9 9 1 TPR repeat TPR_1 PF00515.23 GAK64400.1 - 1.7e-07 30.5 0.3 0.47 10.1 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAK64400.1 - 2.5e-07 30.3 0.0 0.0022 18.0 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAK64400.1 - 6.4e-07 28.7 3.8 0.016 14.9 0.0 6.4 6 1 1 7 7 6 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 GAK64400.1 - 8e-05 22.3 14.8 0.14 11.9 0.0 6.5 5 3 2 8 8 7 2 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.1 GAK64400.1 - 0.00025 20.8 2.6 0.26 11.1 0.0 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat Mad3_BUB1_I PF08311.7 GAK64400.1 - 0.0056 16.4 1.8 0.0056 16.4 1.3 5.1 4 2 1 5 5 5 1 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 GAK64400.1 - 0.73 9.7 30.1 0.97 9.3 0.0 9.5 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAK64400.1 - 1.4 8.9 33.1 0.72 9.8 0.4 8.2 8 3 0 8 8 6 0 Tetratricopeptide repeat SET PF00856.23 GAK64401.1 - 7.8e-26 91.3 0.0 7.8e-26 91.3 0.0 4.2 4 2 0 4 4 4 1 SET domain N-SET PF11764.3 GAK64401.1 - 1.4e-17 64.0 0.0 1.4e-17 64.0 0.0 4.9 5 1 0 5 5 5 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 GAK64401.1 - 1.4e-05 24.3 0.0 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Metallophos_2 PF12850.2 GAK64402.1 - 9.1e-20 71.0 0.1 1.4e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAK64402.1 - 3.9e-05 23.1 1.9 0.029 13.7 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase LSM PF01423.17 GAK64403.1 - 4.6e-16 58.1 0.1 5.8e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Arf PF00025.16 GAK64404.1 - 1.7e-72 242.2 0.0 2.2e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAK64404.1 - 1.2e-11 44.2 0.0 1.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAK64404.1 - 6.4e-11 41.8 0.0 9.2e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAK64404.1 - 1.3e-10 40.5 0.4 1.9e-06 26.8 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAK64404.1 - 4e-10 39.2 0.0 4.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAK64404.1 - 1.1e-06 29.1 0.0 1.5e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAK64404.1 - 0.00016 21.6 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 GAK64405.1 - 1.2e-33 116.3 0.0 2.5e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAK64405.1 - 1.7e-23 83.4 13.7 1.7e-23 83.4 9.5 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 GAK64405.1 - 7.4e-06 26.1 0.0 0.012 15.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 GAK64405.1 - 3.3e-05 23.2 0.1 0.0016 17.7 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAK64405.1 - 9e-05 22.5 0.5 9e-05 22.5 0.3 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAK64405.1 - 0.0021 18.1 0.1 0.016 15.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAK64405.1 - 0.0021 17.2 0.0 0.0044 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 GAK64405.1 - 0.007 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 GAK64405.1 - 0.0089 15.5 0.1 0.026 14.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 GAK64405.1 - 0.038 14.2 0.0 0.35 11.0 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAK64405.1 - 0.049 13.0 0.1 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2408 PF10303.4 GAK64406.1 - 1.5e-55 186.9 1.1 2.2e-38 131.3 0.0 4.5 3 1 1 4 4 4 4 Protein of unknown function (DUF2408) DUF972 PF06156.8 GAK64406.1 - 0.0015 18.8 0.1 0.13 12.6 0.0 3.3 4 1 0 4 4 4 1 Protein of unknown function (DUF972) PilJ PF13675.1 GAK64406.1 - 0.035 14.4 5.7 0.16 12.2 0.6 3.3 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF724 PF05266.9 GAK64406.1 - 0.14 11.7 1.8 0.22 11.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.5 GAK64406.1 - 0.18 11.9 2.3 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4446 PF14584.1 GAK64406.1 - 0.75 9.6 3.0 0.56 10.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Copper-fist PF00649.13 GAK64407.1 - 8.6e-13 47.2 1.8 8.6e-13 47.2 1.3 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain RED_N PF07808.8 GAK64408.1 - 2.7e-10 39.8 1.9 4e-10 39.3 1.3 1.2 1 0 0 1 1 1 1 RED-like protein N-terminal region Phos_pyr_kin PF08543.7 GAK64409.1 - 4.3e-11 42.4 0.0 6.4e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 GAK64409.1 - 1.4e-09 37.5 0.0 1.3e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DUF1690 PF07956.6 GAK64410.1 - 4.8e-15 55.7 5.5 6.1e-15 55.4 3.8 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) STAT_int PF02865.12 GAK64410.1 - 0.01 15.7 0.3 0.12 12.3 0.1 2.0 1 1 1 2 2 2 0 STAT protein, protein interaction domain T2SG PF08334.6 GAK64410.1 - 0.018 14.7 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Seryl_tRNA_N PF02403.17 GAK64410.1 - 0.029 14.3 4.9 0.053 13.5 3.4 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4510 PF14971.1 GAK64410.1 - 0.031 14.4 0.9 0.1 12.7 0.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) Mnd1 PF03962.10 GAK64410.1 - 0.032 13.9 5.7 0.035 13.7 3.9 1.3 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 GAK64410.1 - 0.07 12.0 4.3 0.086 11.7 3.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Piwi PF02171.12 GAK64410.1 - 0.11 11.4 0.1 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Piwi domain IncA PF04156.9 GAK64410.1 - 0.91 9.0 5.8 1.1 8.8 4.0 1.1 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 GAK64410.1 - 1.2 8.9 5.0 2.4 7.9 0.8 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4407 PF14362.1 GAK64410.1 - 1.8 7.4 5.9 1.9 7.3 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.9 GAK64410.1 - 1.9 8.4 8.7 1.2 9.1 4.8 1.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CENP-N PF05238.8 GAK64411.1 - 1.6e-67 228.3 0.0 2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like ArgJ PF01960.13 GAK64412.1 - 8e-133 442.5 0.3 9.7e-133 442.3 0.2 1.0 1 0 0 1 1 1 1 ArgJ family Aminotran_1_2 PF00155.16 GAK64413.1 - 8.5e-31 107.2 0.0 1.1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PCI PF01399.22 GAK64414.1 - 6.1e-19 68.2 0.9 1.3e-18 67.2 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 GAK64414.1 - 8.6e-05 23.0 10.3 0.05 14.2 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAK64414.1 - 0.06 13.1 6.0 15 5.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 GAK64414.1 - 0.47 10.6 4.3 1.1 9.4 0.1 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 GAK64414.1 - 0.65 9.9 3.3 4.9 7.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 GAK64415.1 - 1.7e-34 118.9 0.0 3.1e-34 118.1 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family DUF21 PF01595.15 GAK64416.1 - 3.2e-34 117.8 0.6 6e-34 116.9 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 GAK64416.1 - 2.2e-06 27.3 0.5 0.27 11.0 0.0 3.9 4 0 0 4 4 4 3 CBS domain DcpS_C PF11969.3 GAK64417.1 - 1.7e-12 47.5 0.9 5.4e-12 45.9 0.6 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 GAK64417.1 - 3e-12 46.9 1.1 4.2e-06 27.1 0.1 2.4 2 0 0 2 2 2 2 HIT domain MFS_1_like PF12832.2 GAK64418.1 - 8.8e-21 73.4 0.1 8.8e-21 73.4 0.1 2.3 2 0 0 2 2 2 1 MFS_1 like family CoA_trans PF01144.18 GAK64419.1 - 4.3e-108 359.4 1.5 1.2e-63 214.1 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 GAK64419.1 - 0.00048 19.8 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DeoRC PF00455.17 GAK64419.1 - 0.025 14.2 0.0 0.7 9.5 0.0 2.7 3 0 0 3 3 3 0 DeoR C terminal sensor domain SUI1 PF01253.17 GAK64420.1 - 1.6e-28 98.3 3.2 3e-28 97.4 2.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 GATA PF00320.22 GAK64420.1 - 2.4e-13 49.2 3.4 5.2e-13 48.1 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 GAK64420.1 - 3.6e-08 33.3 0.0 3.8e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 GAK64420.1 - 5.5e-08 33.1 0.2 3.7e-07 30.4 0.0 2.6 3 1 0 3 3 3 1 PAS domain PAS PF00989.19 GAK64420.1 - 1e-07 31.7 0.0 4.1e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 GAK64420.1 - 2.5e-06 27.4 0.0 1.3e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 GAK64420.1 - 0.0063 16.4 0.0 0.021 14.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain TF_Zn_Ribbon PF08271.7 GAK64420.1 - 0.33 10.3 0.3 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding UBX PF00789.15 GAK64421.1 - 4.6e-13 49.0 0.0 9.9e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 GAK64421.1 - 0.0098 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like OmpH PF03938.9 GAK64421.1 - 0.74 9.7 5.9 1.3 8.9 4.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1682 PF07946.9 GAK64421.1 - 0.85 8.4 15.7 1.3 7.8 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ARGLU PF15346.1 GAK64421.1 - 4.3 7.0 28.5 8.4 6.1 19.8 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 WD40 PF00400.27 GAK64422.1 - 4.3e-43 143.6 21.7 7.6e-10 38.2 0.1 11.3 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.7 GAK64422.1 - 9.2e-16 57.7 0.0 1.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 GAK64422.1 - 0.00033 18.9 0.1 0.98 7.4 0.0 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 GAK64422.1 - 0.00065 18.1 0.1 1.3 7.2 0.0 3.2 3 0 0 3 3 3 2 Cytochrome D1 heme domain DUF1513 PF07433.6 GAK64422.1 - 0.062 12.1 0.2 2.4 6.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) YjeF_N PF03853.10 GAK64424.1 - 3.9e-33 114.4 0.0 4.9e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus RabGAP-TBC PF00566.13 GAK64425.1 - 4.9e-31 107.8 0.6 9.7e-31 106.9 0.4 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 GAK64425.1 - 4.7e-05 22.7 0.0 0.0053 16.0 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) Cep57_MT_bd PF06657.8 GAK64426.1 - 6.8e-17 61.1 1.7 6.8e-17 61.1 1.2 3.4 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 PQQ_3 PF13570.1 GAK64427.1 - 0.00021 21.4 3.2 0.017 15.3 0.1 4.0 4 0 0 4 4 4 1 PQQ-like domain Nucleoplasmin PF03066.10 GAK64427.1 - 0.095 12.2 1.6 0.18 11.3 1.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 GAK64427.1 - 8.2 6.8 11.7 0.68 10.2 4.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NMT PF01233.14 GAK64428.1 - 1.1e-76 255.9 0.0 1.8e-76 255.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 GAK64428.1 - 2.5e-64 216.1 0.0 6e-63 211.6 0.0 2.5 2 1 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 GAK64428.1 - 9.8e-05 22.2 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAK64428.1 - 0.02 14.9 0.0 0.71 9.9 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family PBP1_TM PF14812.1 GAK64428.1 - 0.032 14.5 8.9 0.074 13.3 6.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Acetyltransf_7 PF13508.1 GAK64428.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nucleoplasmin PF03066.10 GAK64428.1 - 0.049 13.1 7.0 0.094 12.2 4.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF3258 PF11646.3 GAK64428.1 - 0.12 12.5 0.1 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF3258 DUF2457 PF10446.4 GAK64428.1 - 0.16 10.6 15.5 0.25 10.0 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SGT1 PF07093.6 GAK64428.1 - 0.63 8.3 12.1 0.93 7.7 8.4 1.2 1 0 0 1 1 1 0 SGT1 protein TraF PF13728.1 GAK64428.1 - 1.3 8.4 7.7 2.8 7.3 4.8 1.9 1 1 1 2 2 2 0 F plasmid transfer operon protein TFIIF_alpha PF05793.7 GAK64428.1 - 1.7 6.9 18.2 2.5 6.3 12.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.5 GAK64428.1 - 8.4 6.6 12.3 25 5.1 8.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SOG2 PF10428.4 GAK64429.1 - 5.5e-119 397.7 0.1 5.5e-119 397.7 0.1 4.3 3 1 2 5 5 5 1 RAM signalling pathway protein LRR_4 PF12799.2 GAK64429.1 - 7.6e-16 57.3 4.5 1.2e-05 24.7 0.3 3.8 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK64429.1 - 8.2e-15 54.3 5.4 5.3e-07 29.3 2.1 2.9 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 GAK64429.1 - 1.5e-09 36.5 1.1 0.33 11.1 0.1 5.8 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 GAK64429.1 - 1.4e-06 27.5 3.6 0.94 9.9 0.1 5.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 GAK64429.1 - 0.23 11.6 4.8 1.4 9.2 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat G-patch PF01585.18 GAK64430.1 - 1.8e-11 43.6 3.5 3.5e-11 42.6 2.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAK64430.1 - 1.2e-07 31.4 0.4 2.5e-07 30.4 0.3 1.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site RED_N PF07808.8 GAK64430.1 - 0.078 12.1 0.9 0.77 8.9 0.0 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region zf-C2H2_2 PF12756.2 GAK64430.1 - 0.098 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 GAK64430.1 - 0.11 12.8 0.4 0.2 12.0 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type SAM_2 PF07647.12 GAK64431.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glycos_transf_1 PF00534.15 GAK64432.1 - 6.3e-25 87.5 0.0 1.3e-24 86.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAK64432.1 - 1.8e-06 28.1 0.2 1.5e-05 25.1 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAK64432.1 - 1e-05 25.3 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 GAK64432.1 - 4.4e-05 23.6 0.3 0.0003 20.9 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 GAK64432.1 - 0.00055 20.1 0.1 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 FA_desaturase PF00487.19 GAK64434.1 - 7.8e-29 100.8 16.9 1.4e-28 100.0 11.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 GAK64434.1 - 2.4e-19 68.2 0.7 4.8e-19 67.3 0.5 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) WD40 PF00400.27 GAK64434.1 - 2.1e-16 59.0 3.9 9.2e-05 22.1 1.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Fungal_trans PF04082.13 GAK64435.1 - 1.3e-06 27.4 0.3 2.8e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK64435.1 - 1.4e-05 24.8 10.2 2.3e-05 24.2 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2407 PF10302.4 GAK64436.1 - 5e-13 49.0 0.0 3.7e-11 43.0 0.0 3.0 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 GAK64436.1 - 1.5e-12 47.6 8.4 6.8e-12 45.4 1.0 3.7 3 1 0 3 3 3 1 DUF2407 C-terminal domain ubiquitin PF00240.18 GAK64436.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family ChaC PF04752.7 GAK64438.1 - 1.9e-50 171.2 0.0 3.7e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.26 GAK64438.1 - 1.8e-25 88.4 3.6 4.9e-25 87.0 2.5 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 GAK64438.1 - 4.5e-10 39.3 3.6 2.1e-08 34.0 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAK64438.1 - 1.4e-07 31.5 2.6 2.7e-06 27.3 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAK64438.1 - 2.4e-06 27.5 0.2 0.013 15.6 0.0 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Staphylokinase PF02821.11 GAK64438.1 - 0.0009 19.0 4.9 0.00097 18.9 0.1 2.3 2 0 0 2 2 2 1 Staphylokinase/Streptokinase family zf-C2H2 PF00096.21 GAK64438.1 - 0.0086 16.3 3.1 0.57 10.6 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK64438.1 - 0.048 13.9 2.6 1.9 9.0 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger LUC7 PF03194.10 GAK64439.1 - 2.9e-72 243.2 2.2 2.9e-72 243.2 1.5 1.9 2 0 0 2 2 2 1 LUC7 N_terminus DIM1 PF02966.11 GAK64439.1 - 1e-64 216.0 0.1 1.6e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 TFIIA PF03153.8 GAK64439.1 - 0.0049 16.8 4.4 0.0049 16.8 3.1 3.8 5 0 0 5 5 5 1 Transcription factor IIA, alpha/beta subunit Nitroreductase PF00881.19 GAK64440.1 - 1.3e-08 34.8 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family COX6B PF02297.12 GAK64441.1 - 4e-16 58.7 4.3 4e-16 58.7 3.0 1.6 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 GAK64441.1 - 0.044 13.7 2.3 0.28 11.1 0.4 2.6 2 1 0 2 2 2 0 CHCH domain APOBEC_C PF05240.9 GAK64441.1 - 0.087 12.2 1.2 0.16 11.4 0.9 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Prp18 PF02840.10 GAK64442.1 - 1.6e-57 193.4 0.0 3.1e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 GAK64442.1 - 1.4e-11 43.4 5.5 1.4e-11 43.4 3.8 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DUF515 PF04415.7 GAK64442.1 - 1.2 7.3 5.7 2.4 6.2 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pex2_Pex12 PF04757.9 GAK64443.1 - 6.9e-40 136.8 2.3 9.7e-40 136.4 1.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 GAK64443.1 - 1.8e-05 24.4 2.7 3e-05 23.7 1.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAK64443.1 - 0.0086 16.1 1.4 0.015 15.3 1.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAK64443.1 - 0.064 12.9 2.0 0.11 12.1 1.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK64443.1 - 0.12 12.3 2.5 0.21 11.6 1.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 GAK64444.1 - 2.5e-09 36.5 0.1 4.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAK64444.1 - 1.5e-07 30.7 0.0 2.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAK64444.1 - 0.00039 19.8 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3431 PF11913.3 GAK64444.1 - 0.018 14.4 1.2 0.03 13.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) USP7_ICP0_bdg PF12436.3 GAK64446.1 - 1.1e-84 283.6 2.5 1.3e-84 283.3 1.1 1.6 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 GAK64446.1 - 2e-64 216.9 2.1 1.2e-63 214.3 0.6 2.4 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 GAK64446.1 - 7.5e-58 195.7 0.1 1.2e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK64446.1 - 1.3e-31 110.1 0.0 2e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 GAK64446.1 - 2.4e-08 34.2 0.5 4.8e-07 30.0 0.0 3.4 3 2 0 3 3 3 1 MATH domain SDP_N PF12278.3 GAK64446.1 - 0.044 13.4 0.8 0.082 12.5 0.5 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal Rad60-SLD PF11976.3 GAK64446.1 - 0.079 12.6 0.4 1.6 8.4 0.0 3.2 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Miro PF08477.8 GAK64448.1 - 5.6e-39 133.3 0.0 1.2e-19 70.9 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 GAK64448.1 - 3.3e-35 119.2 0.1 1.8e-34 116.8 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 GAK64448.1 - 6.3e-31 106.9 0.0 5.2e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_2 PF08356.7 GAK64448.1 - 9.4e-28 95.8 0.0 5.2e-27 93.4 0.0 2.1 1 1 0 1 1 1 1 EF hand associated MMR_HSR1 PF01926.18 GAK64448.1 - 5e-09 36.1 0.0 3.8e-06 26.8 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.1 GAK64448.1 - 5.6e-09 36.0 0.4 0.0052 16.8 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAK64448.1 - 3.4e-08 32.2 2.3 0.006 15.8 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAK64448.1 - 3.4e-07 29.5 2.7 0.0063 16.3 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAK64448.1 - 6.8e-06 25.1 4.9 0.037 13.3 0.2 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.16 GAK64448.1 - 1e-05 24.8 0.0 0.049 12.8 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 GAK64448.1 - 0.0001 22.4 0.0 0.83 9.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain SRPRB PF09439.5 GAK64448.1 - 0.00021 20.5 0.0 0.56 9.4 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit MobB PF03205.9 GAK64448.1 - 0.00029 20.5 0.2 0.08 12.6 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_8 PF13833.1 GAK64448.1 - 0.00056 19.4 2.5 0.074 12.6 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair GTP_EFTU PF00009.22 GAK64448.1 - 0.00062 19.2 0.0 0.87 8.9 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAK64448.1 - 0.001 18.5 0.0 0.082 12.3 0.0 2.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 GAK64448.1 - 0.0021 18.3 0.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 GAK64448.1 - 0.0033 17.2 0.2 2.2 8.1 0.0 2.5 2 1 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 GAK64448.1 - 0.0039 17.1 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAK64448.1 - 0.0048 16.5 0.0 0.49 10.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAK64448.1 - 0.0082 16.1 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 GAK64448.1 - 0.011 15.3 0.6 5.4 6.4 0.0 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 GAK64448.1 - 0.012 15.3 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 GAK64448.1 - 0.013 14.8 0.0 0.64 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 GAK64448.1 - 0.015 14.8 0.0 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 GAK64448.1 - 0.02 14.3 0.3 1.6 8.1 0.1 2.5 2 1 1 3 3 2 0 FtsK/SpoIIIE family NOG1 PF06858.9 GAK64448.1 - 0.026 14.4 0.1 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_19 PF13245.1 GAK64448.1 - 0.034 13.8 3.4 0.23 11.2 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain AAA_29 PF13555.1 GAK64448.1 - 0.04 13.4 0.1 3.2 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 GAK64448.1 - 0.045 12.9 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 GAK64448.1 - 0.066 12.4 0.1 0.37 10.0 0.0 2.3 3 0 0 3 3 3 0 Ferrous iron transport protein B RNA_helicase PF00910.17 GAK64448.1 - 0.068 13.3 0.0 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 GAK64448.1 - 0.074 13.2 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 GAK64448.1 - 0.077 12.4 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain EF-hand_10 PF14788.1 GAK64448.1 - 0.082 12.5 2.6 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 EF hand DAP3 PF10236.4 GAK64448.1 - 0.084 11.8 0.1 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 GAK64448.1 - 0.097 12.2 0.0 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAK64448.1 - 0.1 12.9 0.0 20 5.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter VirE PF05272.6 GAK64448.1 - 0.13 11.6 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Virulence-associated protein E NTPase_1 PF03266.10 GAK64448.1 - 0.14 11.9 0.5 0.77 9.4 0.0 2.3 2 1 1 3 3 3 0 NTPase SPARC_Ca_bdg PF10591.4 GAK64448.1 - 0.14 12.1 0.6 6.9 6.7 0.0 3.1 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_14 PF13173.1 GAK64448.1 - 0.14 12.0 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAK64448.1 - 0.15 11.4 2.3 2 7.8 0.1 3.2 4 1 1 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 GAK64448.1 - 0.19 10.6 0.1 0.78 8.6 0.0 1.9 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2075) G-alpha PF00503.15 GAK64448.1 - 0.26 9.9 0.1 4.1 5.9 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit Septin PF00735.13 GAK64448.1 - 0.3 10.0 0.0 4 6.3 0.0 2.2 2 0 0 2 2 2 0 Septin LsmAD PF06741.8 GAK64449.1 - 2e-26 91.8 1.5 2e-26 91.8 1.0 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 GAK64449.1 - 1.1e-18 66.8 0.0 2.3e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain NAD_binding_4 PF07993.7 GAK64450.1 - 3.2e-29 101.5 0.0 5.2e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAK64450.1 - 1.1e-26 93.2 0.1 1.8e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAK64450.1 - 3.1e-05 23.5 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAK64450.1 - 0.0001 22.4 0.0 0.00028 21.0 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Aminotran_5 PF00266.14 GAK64453.1 - 3.8e-31 108.1 0.0 5.4e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V HAD_2 PF13419.1 GAK64454.1 - 7.6e-19 68.6 2.9 1.8e-18 67.3 2.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAK64454.1 - 9.5e-09 34.8 0.0 3.1e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like zf-C3HC4_2 PF13923.1 GAK64455.1 - 9.2e-10 38.3 6.9 1.6e-09 37.6 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK64455.1 - 1.8e-09 37.1 2.6 4.4e-09 35.8 1.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK64455.1 - 4.5e-08 32.8 6.2 7.2e-08 32.1 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAK64455.1 - 1.7e-06 27.5 2.9 2.9e-06 26.8 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK64455.1 - 5.4e-06 26.0 3.9 1e-05 25.1 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAK64455.1 - 9.4e-05 22.2 4.2 9.4e-05 22.2 2.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAK64455.1 - 0.00017 21.1 2.8 0.00018 21.1 1.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger FYVE PF01363.16 GAK64455.1 - 0.059 13.2 0.4 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 GAK64455.1 - 0.27 10.7 3.9 0.56 9.7 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 GAK64455.1 - 7.8 6.1 9.9 18 4.9 6.8 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Gly_transf_sug PF04488.10 GAK64456.1 - 2.2e-05 24.7 0.1 4.6e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SSF PF00474.12 GAK64457.1 - 1.7e-18 66.4 20.4 1.7e-18 66.4 14.1 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family DUF912 PF06024.7 GAK64457.1 - 4.4 7.4 0.0 4.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pyr_redox_3 PF13738.1 GAK64458.1 - 9.7e-10 38.8 0.3 5.1e-05 23.4 0.1 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAK64458.1 - 4.2e-08 32.5 0.0 4.5e-05 22.5 0.0 2.6 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAK64458.1 - 1.4e-06 28.3 0.0 0.0032 17.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK64458.1 - 5.3e-05 22.2 0.1 5.3e-05 22.2 0.1 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK64458.1 - 0.0001 22.1 2.2 0.38 10.5 0.0 3.9 5 0 0 5 5 5 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAK64458.1 - 0.00042 19.4 0.2 0.0012 17.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAK64458.1 - 0.0036 16.2 0.2 2.6 6.8 0.0 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 GAK64458.1 - 0.094 11.1 0.1 1.2 7.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein DUF1654 PF07867.6 GAK64458.1 - 0.11 11.8 0.2 0.25 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) RNA_pol_Rpb1_5 PF04998.12 GAK64460.1 - 2.2e-88 296.1 0.0 4.2e-88 295.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAK64460.1 - 3.6e-60 202.6 0.1 8e-60 201.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAK64460.1 - 3.9e-37 127.4 0.0 7.5e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 GAK64460.1 - 2.5e-25 89.4 9.0 2.4e-21 76.3 0.0 4.7 6 1 0 6 6 6 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 GAK64460.1 - 1.6e-23 82.4 0.0 8.3e-23 80.1 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_clus PF00172.13 GAK64461.1 - 3.3 7.6 9.0 59 3.6 6.3 2.4 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhodopsin PF01036.13 GAK64462.1 - 4.2e-50 170.1 16.4 5.4e-50 169.7 11.4 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Arteri_Gl PF00951.13 GAK64462.1 - 0.25 10.9 6.7 0.091 12.3 1.7 2.1 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF2754 PF10953.3 GAK64462.1 - 1.2 9.2 7.5 3.4 7.7 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) DUF3452 PF11934.3 GAK64463.1 - 0.11 11.7 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Ribonuc_2-5A PF06479.7 GAK64463.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.6 1 1 0 1 1 1 0 Ribonuclease 2-5A NUDIX PF00293.23 GAK64464.1 - 4.6e-10 39.2 0.0 9.2e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Corona_nucleoca PF00937.13 GAK64464.1 - 2.8 6.8 23.0 0.61 8.9 4.4 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Ala_racemase_N PF01168.15 GAK64465.1 - 7.8e-34 117.1 1.2 1.2e-32 113.2 0.3 2.8 2 1 0 2 2 2 1 Alanine racemase, N-terminal domain MCM_bind PF09739.4 GAK64465.1 - 3.5e-23 81.4 0.0 7e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 GAK64465.1 - 5.6e-18 65.0 0.0 1.6e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 Putative alanine racemase CS PF04969.11 GAK64466.1 - 6.7e-20 71.4 0.2 1.1e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 CS domain Metal_resist PF13801.1 GAK64466.1 - 0.0026 17.7 3.4 0.37 10.7 0.0 2.1 2 0 0 2 2 2 2 Heavy-metal resistance 6PF2K PF01591.13 GAK64467.1 - 3.1e-71 238.9 0.0 5e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAK64467.1 - 1.4e-30 106.5 0.2 1.6e-29 103.0 0.0 2.5 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAK64467.1 - 1.4e-09 37.9 0.0 4.6e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK64467.1 - 0.0035 18.1 0.2 0.021 15.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAK64467.1 - 0.0091 15.1 0.0 0.031 13.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.5 GAK64467.1 - 0.013 14.7 0.2 0.068 12.3 0.0 2.3 3 0 0 3 3 3 0 Chromatin associated protein KTI12 RCC1 PF00415.13 GAK64468.1 - 1.8e-20 72.8 0.0 0.00054 20.1 0.0 5.9 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 GAK64468.1 - 5.5e-18 64.9 0.0 2.2e-08 34.0 0.0 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_4 PF13637.1 GAK64468.1 - 2.7e-08 34.0 0.4 2.9e-07 30.8 0.2 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAK64468.1 - 2.8e-08 33.7 0.8 6.9e-07 29.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 GAK64468.1 - 8.1e-06 25.3 16.5 0.0014 18.1 0.0 5.9 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 GAK64468.1 - 0.00056 20.2 0.1 0.002 18.4 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAK64468.1 - 0.0014 18.6 0.7 1.1 9.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat SRP-alpha_N PF04086.8 GAK64468.1 - 0.13 11.6 21.0 0.31 10.3 14.5 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ank PF00023.25 GAK64468.1 - 0.16 11.7 0.4 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat HAUS6_N PF14661.1 GAK64468.1 - 2.7 7.3 15.2 5.9 6.1 10.5 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Bromodomain PF00439.20 GAK64470.1 - 2.6e-56 187.5 0.3 1.1e-19 70.0 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 GAK64470.1 - 2.9e-06 26.6 0.1 0.0015 17.7 0.0 2.8 1 1 1 2 2 2 2 Peptidase family M1 HEAT_2 PF13646.1 GAK64470.1 - 0.033 14.4 7.3 0.37 11.0 0.0 4.1 4 0 0 4 4 4 0 HEAT repeats SKIP_SNW PF02731.10 GAK64471.1 - 7.1e-64 214.0 3.3 7.1e-64 214.0 2.3 2.4 3 0 0 3 3 3 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.7 GAK64471.1 - 2.1 7.9 18.8 0.015 15.0 6.8 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Dynamin_M PF01031.15 GAK64472.1 - 1.2e-103 345.9 0.0 5.5e-103 343.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 GAK64472.1 - 7.3e-54 182.0 0.0 1.3e-53 181.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 GAK64472.1 - 1e-24 86.2 5.4 1e-24 86.2 3.7 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAK64472.1 - 0.0041 17.0 0.8 0.023 14.6 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dus PF01207.12 GAK64472.1 - 0.044 12.6 0.0 0.078 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Baculo_p74 PF04583.7 GAK64472.1 - 0.21 10.7 2.0 13 4.8 0.0 3.5 3 2 0 3 3 3 0 Baculoviridae p74 conserved region Calreticulin PF00262.13 GAK64473.1 - 2.5e-156 519.9 8.2 3.1e-156 519.6 5.7 1.1 1 0 0 1 1 1 1 Calreticulin family NTF2 PF02136.15 GAK64474.1 - 4.5e-34 117.3 0.3 5.4e-34 117.0 0.2 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3402 PF11882.3 GAK64475.1 - 1.4e-157 525.0 0.0 1.1e-154 515.4 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 GAK64475.1 - 1e-38 132.8 0.0 1.8e-37 128.7 0.0 2.3 1 1 0 1 1 1 1 N1221-like protein Internalin_N PF12354.3 GAK64475.1 - 1.1 8.8 3.5 0.79 9.3 0.3 2.2 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal MFS_1 PF07690.11 GAK64476.1 - 1.8e-47 161.8 38.1 2.5e-47 161.3 26.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-DHHC PF01529.15 GAK64477.1 - 0.67 9.3 1.9 25 4.2 0.0 2.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Antimicrobial11 PF08106.6 GAK64477.1 - 0.75 9.7 4.1 15 5.5 0.2 3.0 1 1 1 2 2 2 0 Formaecin family Tetraspannin PF00335.15 GAK64477.1 - 1.5 8.0 12.5 0.026 13.7 0.5 2.4 2 0 0 2 2 2 0 Tetraspanin family HK PF02110.10 GAK64478.1 - 6e-63 212.2 3.4 1.9e-60 204.1 2.3 2.3 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 GAK64478.1 - 7.2e-45 152.3 0.0 1.8e-44 150.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 GAK64478.1 - 0.00021 20.6 0.1 0.00038 19.7 0.1 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PrsW-protease PF13367.1 GAK64478.1 - 0.023 13.9 0.1 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Protease prsW family tRNA-synt_1e PF01406.14 GAK64479.1 - 1.1e-121 405.5 0.0 1.7e-121 405.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 GAK64479.1 - 2.5e-09 36.3 0.5 6.7e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAK64479.1 - 4.5e-05 21.6 0.1 0.021 12.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 GAK64479.1 - 0.00068 19.8 1.7 0.0018 18.5 0.0 2.5 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 GAK64479.1 - 0.0096 14.6 0.6 0.022 13.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 GAK64479.1 - 0.043 12.4 0.0 2.4 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) Sec1 PF00995.18 GAK64480.1 - 6.3e-152 507.1 0.0 7.1e-152 506.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ribonuclease_T2 PF00445.13 GAK64481.1 - 2.8e-39 134.7 0.4 3.9e-39 134.2 0.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family GST_C_2 PF13410.1 GAK64482.1 - 7.8e-10 38.5 0.1 1.6e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAK64482.1 - 1.8e-09 37.6 0.0 4.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAK64482.1 - 9.5e-07 29.2 0.0 2.6e-06 27.8 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAK64482.1 - 0.0012 18.8 0.0 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.17 GAK64483.1 - 2e-15 56.1 0.0 2.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64483.1 - 5.7e-12 45.4 0.0 8.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64483.1 - 4.8e-08 32.7 0.0 8.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAK64483.1 - 0.031 14.1 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif THF_DHG_CYH PF00763.18 GAK64484.1 - 7.5e-17 61.4 0.0 7.7e-15 54.9 0.0 2.4 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 GAK64484.1 - 3.5e-15 55.4 0.1 4.9e-08 32.2 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 GAK64484.1 - 0.012 15.7 0.0 0.75 9.8 0.0 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 GAK64484.1 - 0.033 12.9 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family SBP_bac_5 PF00496.17 GAK64484.1 - 0.047 12.5 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle SNF2_N PF00176.18 GAK64485.1 - 1.5e-84 283.2 0.1 2.6e-84 282.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 GAK64485.1 - 2.6e-40 136.8 0.6 7.6e-40 135.3 0.1 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 GAK64485.1 - 1.7e-33 115.3 0.6 1.7e-33 115.3 0.4 3.5 4 0 0 4 4 3 1 HAND Helicase_C PF00271.26 GAK64485.1 - 3.4e-14 52.4 0.0 2e-13 50.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK64485.1 - 2.3e-07 30.4 0.0 5.9e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAK64485.1 - 3.4e-07 30.2 0.0 3.4e-07 30.2 0.0 3.3 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.26 GAK64485.1 - 0.002 18.1 0.1 0.026 14.5 0.0 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 GAK64485.1 - 0.0088 15.4 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.1 GAK64485.1 - 0.014 15.2 0.0 0.058 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAK64485.1 - 0.06 13.4 0.1 0.44 10.6 0.1 2.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 GAK64485.1 - 0.7 9.4 0.0 0.7 9.4 0.0 4.4 3 2 0 3 3 2 0 AAA domain Telomere_reg-2 PF10193.4 GAK64486.1 - 7.9e-25 87.3 0.0 2.5e-24 85.7 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein PHD PF00628.24 GAK64487.1 - 2.1e-07 30.5 10.5 3.5e-07 29.8 7.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAK64487.1 - 0.0022 17.2 7.1 0.004 16.4 4.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 GAK64487.1 - 0.0022 17.6 3.5 0.0053 16.4 2.4 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger AAA_13 PF13166.1 GAK64488.1 - 1.8e-06 26.7 107.8 0.00082 17.9 11.1 5.7 3 1 3 6 6 6 5 AAA domain Reo_sigmaC PF04582.7 GAK64488.1 - 0.00043 19.5 1.7 0.00043 19.5 1.2 5.9 3 1 2 6 6 6 4 Reovirus sigma C capsid protein Tropomyosin PF00261.15 GAK64488.1 - 0.00045 19.3 8.9 0.00045 19.3 6.2 9.4 3 3 4 7 7 7 1 Tropomyosin Tropomyosin_1 PF12718.2 GAK64488.1 - 0.00073 19.4 59.5 0.0022 17.8 21.7 10.8 4 3 6 11 11 11 2 Tropomyosin like Mto2_bdg PF12808.2 GAK64488.1 - 0.0043 17.1 11.1 0.0043 17.1 7.7 10.7 11 2 0 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region AlphaC_N PF08829.5 GAK64488.1 - 0.014 14.7 0.2 0.057 12.7 0.2 2.0 1 0 0 1 1 1 0 Alpha C protein N terminal LMSTEN PF07988.7 GAK64488.1 - 0.32 10.3 11.1 1.3 8.3 0.2 4.0 4 0 0 4 4 4 0 LMSTEN motif DUF948 PF06103.6 GAK64488.1 - 0.48 10.3 34.7 0.058 13.2 1.2 7.5 5 2 3 8 8 8 0 Bacterial protein of unknown function (DUF948) Zn_clus PF00172.13 GAK64489.1 - 8.2e-08 32.0 7.8 1.3e-07 31.3 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK64489.1 - 2.8e-07 29.6 0.8 1.5e-06 27.2 0.0 2.4 3 1 0 3 3 3 1 Fungal specific transcription factor domain PROL5-SMR PF15621.1 GAK64490.1 - 0.25 11.7 11.9 0.37 11.2 8.3 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Peptidase_M16_C PF05193.16 GAK64491.1 - 7.6e-44 149.5 0.0 1.4e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAK64491.1 - 5.6e-42 143.0 0.0 1.3e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Abhydrolase_6 PF12697.2 GAK64492.1 - 9.8e-21 74.6 0.2 1.6e-20 73.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK64492.1 - 7.3e-12 45.2 0.0 1.6e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK64492.1 - 4e-06 26.5 0.1 0.0031 17.1 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAK64492.1 - 0.00056 19.7 0.2 0.0011 18.7 0.2 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 GAK64492.1 - 0.00096 18.4 0.2 1.1 8.5 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 GAK64492.1 - 0.0089 15.4 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Putative esterase MFS_1 PF07690.11 GAK64493.1 - 1.3e-35 122.8 53.0 1.3e-35 122.8 36.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK64493.1 - 2.9e-12 45.8 7.4 2.9e-12 45.8 5.1 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter COX4 PF02936.9 GAK64493.1 - 0.07 12.8 0.6 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Asp PF00026.18 GAK64494.1 - 9.7e-70 235.3 0.5 1.2e-69 234.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAK64494.1 - 1.8e-08 34.4 0.1 5.3e-08 32.9 0.1 1.9 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAK64494.1 - 8.9e-07 29.3 1.9 0.0047 17.3 0.0 3.5 2 1 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 GAK64494.1 - 0.014 15.2 0.2 0.065 13.0 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 GAK64494.1 - 0.063 13.2 0.1 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Syja_N PF02383.13 GAK64496.1 - 1.3e-83 280.4 0.0 1.9e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 GAK64496.1 - 3.3e-28 99.2 0.8 6.7e-28 98.2 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family F-box-like PF12937.2 GAK64497.1 - 3.2e-10 39.5 0.9 3.2e-10 39.5 0.6 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAK64497.1 - 1.4e-05 24.5 0.2 6.8e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 F-box domain WD40 PF00400.27 GAK64497.1 - 0.049 13.5 0.0 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_2 PF13360.1 GAK64497.1 - 0.092 12.1 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain ATP_synt_H PF05493.8 GAK64498.1 - 1.3e-20 73.2 4.3 1.4e-20 73.0 3.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 GAK64498.1 - 0.1 11.9 0.8 0.1 11.9 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3093 PF11292.3 GAK64498.1 - 0.54 10.0 3.9 0.6 9.9 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) NAD_binding_2 PF03446.10 GAK64499.1 - 1e-18 67.6 0.0 1.8e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAK64499.1 - 1.3e-10 41.4 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 GAK64499.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAK64499.1 - 2e-05 24.9 0.0 8.2e-05 22.9 0.0 2.0 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 GAK64499.1 - 0.0073 16.5 0.0 0.09 13.0 0.0 2.5 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAK64499.1 - 0.041 13.0 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 GAK64499.1 - 0.048 12.4 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Rad21_Rec8_N PF04825.8 GAK64500.1 - 2.9e-42 143.1 0.1 5.2e-42 142.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 GAK64500.1 - 5.4e-16 57.5 0.0 1.5e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 GAK64500.1 - 0.0002 21.0 0.0 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 1 ScpA/B protein Macoilin PF09726.4 GAK64501.1 - 7.9 4.6 15.0 13 3.9 10.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Cyclin_N PF00134.18 GAK64504.1 - 6.6e-44 148.5 0.3 1e-41 141.4 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAK64504.1 - 3.3e-26 91.5 0.0 3.3e-26 91.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain zf-MYND PF01753.13 GAK64506.1 - 1.8e-06 27.6 16.0 4.4e-06 26.4 11.1 1.7 1 0 0 1 1 1 1 MYND finger Toxin_3 PF00537.13 GAK64506.1 - 0.27 11.1 6.2 0.54 10.1 4.3 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain CLPTM1 PF05602.7 GAK64507.1 - 1.7e-103 346.6 0.0 3.9e-103 345.5 0.0 1.5 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 GAK64507.1 - 7.7e-05 22.1 0.5 7.7e-05 22.1 0.3 2.2 3 0 0 3 3 3 1 PQ loop repeat DUF456 PF04306.8 GAK64507.1 - 0.03 14.3 3.6 0.1 12.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF456) MFS_1 PF07690.11 GAK64508.1 - 3.1e-27 95.2 30.4 3.1e-27 95.2 21.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK64508.1 - 1.1e-06 27.5 22.7 4.3e-06 25.5 15.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter AMP-binding PF00501.23 GAK64510.1 - 6e-73 245.6 0.0 7.7e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK64510.1 - 6.4e-08 33.4 0.1 1.4e-07 32.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PLU-1 PF08429.6 GAK64511.1 - 7.9e-83 278.1 3.3 4.1e-82 275.7 1.3 2.4 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 GAK64511.1 - 1.9e-42 144.1 0.4 3.7e-42 143.1 0.3 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 GAK64511.1 - 1.8e-26 91.5 37.7 1.5e-12 46.9 2.4 4.4 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 GAK64511.1 - 3.7e-19 68.3 0.0 7.9e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 GAK64511.1 - 5.9e-14 51.2 1.2 1.1e-13 50.4 0.8 1.5 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 GAK64511.1 - 5e-11 42.5 0.3 5e-11 42.5 0.2 2.4 3 0 0 3 3 2 1 C5HC2 zinc finger PHD_2 PF13831.1 GAK64511.1 - 7.1e-05 22.0 24.8 0.026 13.8 2.7 3.9 4 0 0 4 4 4 3 PHD-finger zf-HC5HC2H PF13771.1 GAK64511.1 - 0.0063 16.6 10.5 3.1 8.0 0.1 3.5 3 0 0 3 3 3 2 PHD-like zinc-binding domain Fe-ADH_2 PF13685.1 GAK64511.1 - 0.012 14.9 0.1 0.03 13.6 0.1 1.6 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase TusA PF01206.12 GAK64511.1 - 0.012 15.1 0.3 0.94 9.1 0.1 2.6 2 0 0 2 2 2 0 Sulfurtransferase TusA C1_1 PF00130.17 GAK64511.1 - 0.21 11.3 24.9 0.56 9.9 0.8 4.3 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Thg1 PF04446.7 GAK64511.1 - 0.23 11.0 0.0 0.5 9.9 0.0 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase E1-E2_ATPase PF00122.15 GAK64512.1 - 1.1e-66 224.1 6.9 4e-66 222.3 0.5 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 GAK64512.1 - 3.3e-24 86.5 0.8 1.1e-23 84.8 0.6 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAK64512.1 - 3.5e-13 50.1 0.0 6.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK64512.1 - 2.1e-10 39.9 0.0 4.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus YrvL PF14184.1 GAK64512.1 - 0.00087 19.0 4.2 0.00087 19.0 2.9 2.4 2 0 0 2 2 2 1 Regulatory protein YrvL Hydrolase_3 PF08282.7 GAK64512.1 - 0.00089 18.9 0.3 0.0023 17.5 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK64512.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Methyltransf_16 PF10294.4 GAK64513.1 - 2.4e-14 53.1 0.0 1.9e-13 50.2 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 GAK64513.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RPA_C PF08784.6 GAK64515.1 - 8e-16 58.3 1.8 8.3e-16 58.2 0.4 1.6 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 GAK64515.1 - 1.9e-08 34.0 0.1 3.2e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4402 PF14352.1 GAK64515.1 - 0.032 14.6 0.5 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) Het-C PF07217.6 GAK64516.1 - 2.5e-229 762.4 0.0 4.7e-229 761.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C OrfB_Zn_ribbon PF07282.6 GAK64516.1 - 0.025 14.2 0.3 0.071 12.7 0.2 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain 6PGD PF00393.14 GAK64517.1 - 6.8e-134 445.6 0.0 2e-133 444.0 0.0 1.7 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAK64517.1 - 1.8e-53 180.7 0.1 3.8e-53 179.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAK64517.1 - 0.048 14.0 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 GAK64517.1 - 0.099 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sterol-sensing PF12349.3 GAK64518.1 - 2.5e-47 160.1 10.8 4.3e-47 159.4 7.5 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 GAK64518.1 - 2.6e-17 62.0 5.3 3.7e-17 61.5 3.7 1.1 1 0 0 1 1 1 1 Patched family ADH_zinc_N PF00107.21 GAK64519.1 - 9.4e-12 44.6 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK64519.1 - 4e-08 32.9 0.0 9.5e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain JmjC PF02373.17 GAK64520.1 - 1.8e-09 37.8 0.0 4.2e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cript PF10235.4 GAK64520.1 - 0.7 10.2 12.4 0.068 13.5 1.1 2.9 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT UFD1 PF03152.9 GAK64523.1 - 8.5e-67 223.6 0.0 1.1e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Cpn60_TCP1 PF00118.19 GAK64524.1 - 1.2e-139 466.1 12.4 1.6e-139 465.7 8.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chitin_synth_2 PF03142.10 GAK64526.1 - 1.6e-290 964.0 0.0 2e-290 963.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 GAK64526.1 - 3e-17 62.9 1.1 7.5e-17 61.6 0.8 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK64526.1 - 1.6e-15 57.5 0.0 3.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAK64526.1 - 3.6e-06 26.3 0.0 0.00061 19.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Cyt-b5 PF00173.23 GAK64526.1 - 1.6e-05 24.6 0.0 3.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 GAK64526.1 - 0.00082 19.1 0.0 0.0031 17.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 4HB_MCP_1 PF12729.2 GAK64526.1 - 8.2 5.7 2.8 2.8 7.2 0.0 1.5 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction ABC_membrane PF00664.18 GAK64527.1 - 8.7e-74 248.3 21.7 4.6e-40 137.7 6.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAK64527.1 - 5.7e-51 172.4 0.1 2.2e-31 108.9 0.1 2.9 2 1 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 GAK64527.1 - 1.8e-05 24.8 2.8 0.0057 16.6 0.5 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAK64527.1 - 4e-05 22.9 0.3 0.47 9.6 0.1 3.9 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 GAK64527.1 - 0.00014 21.7 2.5 0.26 11.0 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 GAK64527.1 - 0.00016 21.6 0.1 0.31 11.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 GAK64527.1 - 0.0018 17.7 0.9 2.4 7.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 GAK64527.1 - 0.0024 16.8 0.2 0.26 10.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 GAK64527.1 - 0.0025 17.2 0.1 1.2 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 GAK64527.1 - 0.0027 17.5 3.5 0.06 13.1 0.0 2.9 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 GAK64527.1 - 0.0029 18.0 1.7 2.2 8.7 0.1 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 GAK64527.1 - 0.0046 16.1 0.2 1.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 GAK64527.1 - 0.012 15.5 0.0 7.9 6.3 0.0 3.5 2 2 0 3 3 3 0 AAA domain MpPF26 PF07666.6 GAK64527.1 - 0.039 13.8 0.4 0.2 11.5 0.3 2.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 DUF815 PF05673.8 GAK64527.1 - 0.11 11.4 0.7 2.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sre PF03125.13 GAK64527.1 - 0.13 11.1 3.7 0.3 9.9 0.1 2.9 3 1 1 4 4 4 0 C. elegans Sre G protein-coupled chemoreceptor AAA_10 PF12846.2 GAK64527.1 - 0.18 11.1 3.2 9.2 5.5 0.1 3.0 3 0 0 3 3 3 0 AAA-like domain Hat1_N PF10394.4 GAK64528.1 - 5.2e-38 130.6 0.0 1e-37 129.6 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 GAK64528.1 - 0.00043 20.3 0.0 0.0022 18.1 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 GAK64528.1 - 0.00071 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 GAK64528.1 - 0.00099 19.1 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK64528.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IMPDH PF00478.20 GAK64529.1 - 2e-136 454.5 0.0 1.2e-135 451.9 0.0 2.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 GAK64529.1 - 1.2e-19 69.8 0.1 4.9e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 GAK64529.1 - 1.6e-11 43.9 8.5 1.5e-08 34.2 5.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 GAK64529.1 - 1.1e-09 37.6 1.6 2.9e-09 36.2 1.1 1.7 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 GAK64529.1 - 1.8e-08 33.9 2.1 4.9e-08 32.5 1.4 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 GAK64529.1 - 0.00055 19.0 3.6 0.00059 18.9 1.6 1.7 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 GAK64529.1 - 0.0096 14.8 0.7 0.11 11.4 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF561) Dus PF01207.12 GAK64529.1 - 0.036 12.9 0.8 0.3 9.8 0.0 2.3 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) PcrB PF01884.12 GAK64529.1 - 0.093 11.9 1.6 3.6 6.7 0.0 3.3 4 0 0 4 4 4 0 PcrB family EAL PF00563.15 GAK64529.1 - 0.18 11.2 0.1 14 5.0 0.0 2.2 2 0 0 2 2 2 0 EAL domain DHO_dh PF01180.16 GAK64529.1 - 0.6 9.0 4.8 0.2 10.5 0.4 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase RRP7 PF12923.2 GAK64530.1 - 2.1e-33 115.1 1.1 1.5e-31 109.1 0.0 2.7 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 GAK64530.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64530.1 - 0.00016 21.5 0.0 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.1 GAK64530.1 - 0.38 11.2 5.3 0.13 12.7 0.7 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PBP1_TM PF14812.1 GAK64530.1 - 0.39 11.0 3.3 0.93 9.8 2.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim17 PF02466.14 GAK64531.1 - 8e-35 119.6 6.9 9.9e-35 119.3 4.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 GAK64531.1 - 0.08 12.9 0.5 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) AAA PF00004.24 GAK64532.1 - 3.4e-41 140.5 0.0 5.5e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAK64532.1 - 5.7e-07 29.7 0.3 0.00013 22.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAK64532.1 - 1.9e-05 24.6 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAK64532.1 - 4.6e-05 22.4 0.0 9.8e-05 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 GAK64532.1 - 0.0003 20.8 0.1 0.003 17.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 GAK64532.1 - 0.00032 20.4 0.3 0.0024 17.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAK64532.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAK64532.1 - 0.0031 17.4 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK64532.1 - 0.0061 17.3 1.0 0.013 16.2 0.2 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 GAK64532.1 - 0.0061 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAK64532.1 - 0.0065 16.0 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 GAK64532.1 - 0.0076 15.3 0.1 0.2 10.7 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_19 PF13245.1 GAK64532.1 - 0.0081 15.8 0.3 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 GAK64532.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 GAK64532.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAK64532.1 - 0.019 14.3 1.1 2.5 7.4 0.2 2.4 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 GAK64532.1 - 0.025 13.4 0.0 0.06 12.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 GAK64532.1 - 0.031 14.2 0.5 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAK64532.1 - 0.042 12.9 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 GAK64532.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 GAK64532.1 - 0.08 12.6 0.2 0.48 10.0 0.1 2.1 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.8 GAK64532.1 - 0.083 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 GAK64532.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Histone PF00125.19 GAK64532.1 - 0.092 12.8 0.2 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PhoH PF02562.11 GAK64532.1 - 0.16 11.2 0.2 0.45 9.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Nop PF01798.13 GAK64533.1 - 3.4e-58 195.2 0.6 7.6e-58 194.0 0.4 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAK64533.1 - 5e-27 93.4 0.0 9e-27 92.6 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAK64533.1 - 2.3e-15 56.5 0.3 2.3e-15 56.5 0.2 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF2992 PF11208.3 GAK64533.1 - 0.28 11.0 11.0 0.99 9.3 7.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF4446 PF14584.1 GAK64533.1 - 5.8 6.7 7.3 15 5.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) EMP24_GP25L PF01105.19 GAK64534.1 - 3.2e-47 160.6 0.0 3.6e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Apocytochr_F_C PF01333.14 GAK64534.1 - 0.071 12.9 0.1 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Apocytochrome F, C-terminal Ran_BP1 PF00638.13 GAK64535.1 - 2.9e-51 172.6 1.0 4.1e-51 172.1 0.7 1.2 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 GAK64535.1 - 3.7e-05 23.3 0.9 5.5e-05 22.7 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 GAK64535.1 - 0.00024 20.7 0.9 0.0011 18.6 0.6 1.9 1 1 0 1 1 1 1 WH1 domain Tau95 PF09734.4 GAK64536.1 - 8.2e-48 163.3 0.0 1e-47 162.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit SSDP PF04503.8 GAK64536.1 - 0.028 14.1 1.2 0.051 13.3 0.9 1.3 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP Pol_alpha_B_N PF08418.5 GAK64537.1 - 6.3e-54 183.1 0.0 8.8e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 GAK64537.1 - 2.1e-24 85.9 0.0 3e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B BTG PF07742.7 GAK64538.1 - 2.8e-24 84.9 0.0 4.6e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 BTG family DUF1162 PF06650.7 GAK64539.1 - 3.3e-73 246.2 0.0 1.9e-70 237.2 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAK64539.1 - 1.6e-39 134.0 0.2 4e-39 132.7 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 GAK64539.1 - 4.1e-07 30.0 0.0 1.4e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Methyltransf_16 PF10294.4 GAK64540.1 - 2.8e-17 62.7 0.0 6.8e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 GAK64540.1 - 0.069 13.9 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sec8_exocyst PF04048.9 GAK64541.1 - 3e-39 133.9 0.4 6.4e-39 132.8 0.3 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 GAK64541.1 - 3.2e-06 26.2 0.4 6e-06 25.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 GAK64541.1 - 0.0011 18.8 2.0 0.003 17.4 0.3 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 WIYLD PF10440.4 GAK64541.1 - 0.24 11.3 0.0 1 9.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Ribosomal_S5_C PF03719.10 GAK64542.1 - 5.1e-16 57.7 0.0 1.2e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 GAK64542.1 - 1.2e-13 50.6 0.7 2.2e-13 49.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF566 PF04484.7 GAK64542.1 - 6.4 6.1 15.5 11 5.4 10.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) RRM_1 PF00076.17 GAK64543.1 - 7.4e-35 118.4 0.0 2.8e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64543.1 - 1e-27 95.8 0.0 2.4e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64543.1 - 8.3e-09 35.1 0.0 0.00074 19.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.22 GAK64543.1 - 0.21 10.9 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.10 GAK64545.1 - 0.0014 18.3 0.7 0.0014 18.3 0.5 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAK64545.1 - 0.0051 16.9 3.2 0.0065 16.6 0.2 2.4 2 0 0 2 2 2 1 Complex1_LYR-like DHC PF09626.5 GAK64545.1 - 0.042 14.5 0.5 4.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Dihaem cytochrome c zf-C2H2 PF00096.21 GAK64546.1 - 0.00031 20.9 17.6 0.022 15.0 2.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK64546.1 - 0.026 14.8 23.1 0.037 14.3 2.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAK64546.1 - 0.4 10.9 9.6 0.14 12.3 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAK64546.1 - 5.8 6.9 8.9 0.51 10.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PX PF00787.19 GAK64547.1 - 3.9e-17 62.0 0.0 1.4e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 GAK64547.1 - 7.6e-08 31.9 0.1 4.2e-07 29.4 0.1 2.2 2 1 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.23 GAK64547.1 - 0.0092 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain HTH_27 PF13463.1 GAK64547.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Glyco_hydro_43 PF04616.9 GAK64548.1 - 2.7e-08 33.2 0.6 1.5e-07 30.7 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Sec62 PF03839.11 GAK64549.1 - 3.9e-45 153.9 4.3 1.2e-44 152.4 3.0 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 Cnd1 PF12717.2 GAK64550.1 - 1.5e-64 217.1 3.0 3.7e-58 196.2 0.0 3.2 3 1 1 4 4 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 GAK64550.1 - 2.8e-53 180.0 0.0 2.8e-53 180.0 0.0 3.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.17 GAK64550.1 - 1.7e-10 40.0 1.6 3.3 8.0 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 GAK64550.1 - 4.7e-10 39.6 3.6 0.00064 19.9 0.0 6.2 6 1 1 7 7 6 2 HEAT repeats Adaptin_N PF01602.15 GAK64550.1 - 4.5e-07 28.5 1.3 0.0012 17.2 0.4 3.5 3 1 0 3 3 3 2 Adaptin N terminal region Nop14 PF04147.7 GAK64550.1 - 2.9e-05 22.2 20.1 3.4e-05 22.0 9.9 3.1 4 0 0 4 4 4 1 Nop14-like family Cohesin_HEAT PF12765.2 GAK64550.1 - 0.00083 19.2 0.9 0.044 13.7 0.0 4.3 4 1 1 5 5 4 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 GAK64550.1 - 0.0017 17.4 0.9 0.01 14.8 0.1 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 GAK64550.1 - 0.0026 17.5 0.0 2.7 7.9 0.0 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2435) SDA1 PF05285.7 GAK64550.1 - 0.0027 17.0 18.6 0.0027 17.0 12.9 2.2 2 0 0 2 2 2 1 SDA1 Sigma70_ner PF04546.8 GAK64550.1 - 0.0053 16.3 12.2 0.025 14.1 8.5 2.2 1 0 0 1 1 1 1 Sigma-70, non-essential region SPX PF03105.14 GAK64550.1 - 0.008 15.9 0.6 0.014 15.2 0.4 1.4 1 0 0 1 1 1 1 SPX domain HEAT_EZ PF13513.1 GAK64550.1 - 0.036 14.5 15.6 0.062 13.8 0.3 6.3 5 1 1 6 6 5 0 HEAT-like repeat FANCI_S2 PF14676.1 GAK64550.1 - 0.06 13.2 0.5 5.5 6.8 0.0 3.6 3 0 0 3 3 3 0 FANCI solenoid 2 TFIIA PF03153.8 GAK64550.1 - 0.078 12.8 11.0 0.23 11.3 7.6 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 GAK64550.1 - 0.13 10.3 16.6 0.21 9.5 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 GAK64550.1 - 2 7.0 23.5 3.9 6.0 16.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 GAK64550.1 - 6.7 4.9 23.6 16 3.6 16.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPR_14 PF13428.1 GAK64551.1 - 0.066 13.8 7.1 2.7 8.8 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat CwfJ_C_1 PF04677.10 GAK64552.1 - 1.1e-13 50.9 0.0 2.1e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.1 GAK64552.1 - 1.8e-06 27.3 0.7 3.9e-06 26.2 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle CwfJ_C_2 PF04676.9 GAK64552.1 - 5.4e-05 23.6 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.18 GAK64552.1 - 0.0043 16.9 0.2 0.0043 16.9 0.2 2.2 3 0 0 3 3 3 1 Zinc knuckle DUF3420 PF11900.3 GAK64552.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) VMA21 PF09446.5 GAK64553.1 - 2e-10 40.4 5.4 2.8e-10 39.9 3.8 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1229 PF06797.6 GAK64553.1 - 0.079 11.7 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) ORC2 PF04084.9 GAK64554.1 - 1e-80 271.0 0.0 1.3e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Serglycin PF04360.7 GAK64554.1 - 0.047 13.4 4.1 0.051 13.3 1.5 2.0 2 0 0 2 2 2 0 Serglycin PIN_4 PF13638.1 GAK64555.1 - 1.3e-23 83.5 0.0 2.2e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 PIN domain DUF1572 PF07609.6 GAK64561.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) DLH PF01738.13 GAK64563.1 - 3.6e-24 85.2 0.1 6.2e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAK64563.1 - 0.0012 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK64563.1 - 0.065 13.0 0.0 3.8 7.3 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Phosphodiest PF01663.17 GAK64564.1 - 1.7e-71 241.5 0.3 2.1e-71 241.2 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SHNi-TPR PF10516.4 GAK64565.1 - 4.3e-11 41.8 0.2 1.1e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_11 PF13414.1 GAK64565.1 - 1.8e-06 27.5 5.6 0.0048 16.5 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 GAK64565.1 - 0.00023 21.0 11.5 0.0028 17.5 0.8 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAK64565.1 - 0.073 13.0 6.3 3.2 7.8 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glutaredoxin2_C PF04399.8 GAK64565.1 - 0.17 11.4 0.9 0.97 9.0 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain MSP1_C PF07462.6 GAK64565.1 - 0.17 10.2 7.7 0.15 10.4 4.3 1.7 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF177 PF02620.12 GAK64565.1 - 0.17 11.9 1.7 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized ACR, COG1399 CHASE3 PF05227.8 GAK64565.1 - 0.76 9.4 10.6 5.1 6.7 0.1 3.1 2 1 1 3 3 3 0 CHASE3 domain TPR_11 PF13414.1 GAK64567.1 - 1.3e-26 91.9 18.1 3.7e-13 48.9 0.1 4.0 3 1 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 GAK64567.1 - 1.5e-23 81.3 2.2 5.3e-08 32.1 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAK64567.1 - 1e-21 75.0 11.3 2.4e-06 27.0 0.1 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAK64567.1 - 1.5e-13 51.0 13.7 3.5e-08 33.8 0.1 5.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAK64567.1 - 1.9e-13 49.1 0.2 0.0047 16.6 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAK64567.1 - 2.2e-13 49.5 11.5 0.00065 20.1 0.0 6.4 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAK64567.1 - 2.8e-13 48.8 3.8 0.0005 20.0 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAK64567.1 - 1.5e-11 44.0 10.7 4.5e-06 26.5 0.0 4.5 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAK64567.1 - 1.7e-10 41.0 9.2 0.0019 18.4 1.2 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAK64567.1 - 1.5e-06 27.5 2.2 0.046 13.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAK64567.1 - 3.4e-06 27.1 5.8 0.67 10.5 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAK64567.1 - 0.00023 21.2 9.3 0.039 14.0 0.2 5.0 4 1 2 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 GAK64567.1 - 0.00023 21.2 3.8 0.0025 17.9 0.3 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 GAK64567.1 - 0.018 15.3 13.3 0.14 12.4 2.1 4.2 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 GAK64567.1 - 0.039 13.8 9.6 0.88 9.6 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 GAK64567.1 - 0.15 11.2 1.5 3.6 6.7 0.1 2.8 3 1 0 3 3 3 0 Coatomer epsilon subunit TPR_9 PF13371.1 GAK64567.1 - 0.18 11.6 8.4 2.6 7.9 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Glyco_transf_28 PF03033.15 GAK64568.1 - 3.9e-20 72.0 0.0 8.1e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 GAK64568.1 - 6.8e-05 22.3 0.0 0.00052 19.4 0.0 2.2 2 0 0 2 2 2 1 GRAM domain UDPGT PF00201.13 GAK64568.1 - 0.014 13.9 0.1 0.037 12.5 0.0 1.6 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase RNase_P_Rpp14 PF01900.14 GAK64569.1 - 2.9e-20 72.1 0.0 5.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Rpp14/Pop5 family IBR PF01485.16 GAK64570.1 - 6.8e-20 70.7 37.5 2.2e-12 46.6 2.9 4.3 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 GAK64570.1 - 6.1e-10 38.9 2.6 2.5e-09 36.9 1.8 2.0 1 1 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 GAK64570.1 - 2.7e-08 33.5 6.3 2.7e-08 33.5 4.3 4.7 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAK64570.1 - 8.7e-05 22.4 7.5 8.7e-05 22.4 5.2 4.5 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK64570.1 - 0.00033 20.2 6.5 0.00033 20.2 4.5 4.5 3 1 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK64570.1 - 0.0074 15.9 7.7 0.0074 15.9 5.4 4.2 4 0 0 4 4 4 1 zinc-RING finger domain DUF3025 PF11227.3 GAK64570.1 - 0.038 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Baculo_RING PF05883.6 GAK64570.1 - 4.2 7.2 7.1 0.71 9.7 0.6 2.4 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF3414 PF11894.3 GAK64572.1 - 0 1429.7 0.0 0 1429.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Glyco_hydro_45 PF02015.11 GAK64573.1 - 1e-51 175.8 12.3 1.4e-51 175.4 8.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Abhydrolase_3 PF07859.8 GAK64577.1 - 2.7e-36 125.1 0.2 5.4e-36 124.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 GAK64577.1 - 2.8e-06 26.3 0.8 5.1e-06 25.4 0.0 1.8 3 0 0 3 3 3 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAK64577.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 GAK64577.1 - 0.033 12.8 0.0 6.6 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2424) Spc97_Spc98 PF04130.8 GAK64578.1 - 4.2e-90 302.5 0.0 7.1e-90 301.8 0.0 1.3 1 1 0 1 1 1 1 Spc97 / Spc98 family Alg6_Alg8 PF03155.10 GAK64579.1 - 3.9e-114 382.0 20.5 6e-53 180.3 0.1 3.1 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family Ribosomal_L37ae PF01780.14 GAK64580.1 - 2e-40 136.5 7.7 2.7e-40 136.1 5.3 1.2 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-BED PF02892.10 GAK64580.1 - 0.017 14.8 2.4 1.5 8.6 1.7 2.5 1 1 0 1 1 1 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 GAK64580.1 - 0.024 14.4 2.2 0.04 13.7 1.5 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 GAK64580.1 - 0.17 11.8 1.3 0.91 9.5 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.5 GAK64580.1 - 0.51 9.8 2.4 0.61 9.6 0.1 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain Ribosomal_L44 PF00935.14 GAK64580.1 - 7.2 6.6 9.0 2.7 8.0 2.4 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Amidase PF01425.16 GAK64581.1 - 2.7e-68 230.8 2.5 7.8e-66 222.7 1.5 2.1 2 0 0 2 2 2 2 Amidase G-alpha PF00503.15 GAK64582.1 - 2e-115 385.5 0.6 2.5e-115 385.2 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAK64582.1 - 4.6e-13 48.7 0.1 4.9e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 GAK64582.1 - 0.0015 18.9 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAK64582.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAK64582.1 - 0.022 14.7 0.0 6.8 6.6 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2985 PF11204.3 GAK64582.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Gtr1_RagA PF04670.7 GAK64582.1 - 0.067 12.3 2.5 4.4 6.3 0.0 2.5 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 GAK64582.1 - 0.094 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MRP-L47 PF06984.8 GAK64583.1 - 1.7e-15 56.6 2.9 7.2e-15 54.6 1.9 2.1 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 GAK64583.1 - 0.043 13.5 1.0 0.17 11.6 0.2 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein Ribosomal_S24e PF01282.14 GAK64584.1 - 6e-32 109.2 0.0 1e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e HVSL PF09749.4 GAK64585.1 - 5.6e-32 110.6 0.0 8e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 GAK64585.1 - 0.00043 20.0 0.1 0.0009 18.9 0.1 1.6 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Pkinase PF00069.20 GAK64586.1 - 2.8e-55 187.2 0.0 8.2e-55 185.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64586.1 - 7.1e-25 87.5 0.0 1.5e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Borrelia_P83 PF05262.6 GAK64586.1 - 2.2 6.4 4.0 3.4 5.8 2.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PFK PF00365.15 GAK64587.1 - 1.4e-164 545.8 3.1 2.9e-96 321.7 0.6 3.2 3 0 0 3 3 3 3 Phosphofructokinase PapJ PF14855.1 GAK64587.1 - 0.039 13.4 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Cyclase PF04199.8 GAK64588.1 - 3.3e-14 52.9 1.9 5.9e-14 52.1 1.2 1.5 1 1 0 1 1 1 1 Putative cyclase DUF221 PF02714.10 GAK64589.1 - 2.4e-100 335.5 13.9 2.4e-100 335.5 9.6 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAK64589.1 - 3.2e-38 130.7 4.2 3.2e-38 130.7 2.9 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAK64589.1 - 4.4e-21 75.1 0.9 7.9e-21 74.3 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 GAK64589.1 - 1.6e-13 50.3 0.0 3.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein Glyco_hydro_28 PF00295.12 GAK64590.1 - 4e-111 371.0 18.9 4.6e-111 370.9 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TRAM_LAG1_CLN8 PF03798.11 GAK64592.1 - 2.9e-07 30.2 12.5 2.9e-07 30.2 8.7 1.6 1 1 1 2 2 2 1 TLC domain Aldedh PF00171.17 GAK64593.1 - 6e-182 605.0 0.2 6.8e-182 604.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK64593.1 - 0.00017 20.4 0.0 0.00026 19.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 GAK64593.1 - 0.00025 20.3 0.0 0.0018 17.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) GFA PF04828.9 GAK64595.1 - 1.4e-20 72.9 3.7 2e-20 72.5 2.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme OSTMP1 PF09777.4 GAK64595.1 - 0.024 13.8 1.4 0.034 13.3 1.0 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor COG7 PF10191.4 GAK64596.1 - 0.095 10.6 0.0 0.13 10.1 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF1816 PF08846.5 GAK64596.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) FAA_hydrolase PF01557.13 GAK64597.1 - 3.8e-64 216.1 0.0 6e-64 215.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 GAK64597.1 - 5e-35 121.4 2.4 7.5e-35 120.8 1.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK64597.1 - 2.5e-24 86.1 0.7 1.8e-17 63.6 0.4 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK64597.1 - 5.9e-16 58.5 2.1 1.9e-15 56.8 1.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAK64597.1 - 2.3e-05 23.0 0.0 3.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.8 GAK64597.1 - 6.5e-05 22.6 0.5 0.00094 18.8 0.2 2.2 1 1 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.3 GAK64597.1 - 0.0014 18.4 0.2 0.0045 16.8 0.1 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 GAK64597.1 - 0.0017 18.2 0.0 0.0053 16.6 0.0 1.9 1 0 0 1 1 1 1 TAP-like protein PGAP1 PF07819.8 GAK64597.1 - 0.025 14.1 1.1 0.092 12.3 0.6 2.0 2 1 0 2 2 2 0 PGAP1-like protein KH_2 PF07650.12 GAK64597.1 - 0.031 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 KH domain Esterase PF00756.15 GAK64597.1 - 0.039 13.3 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Grp1_Fun34_YaaH PF01184.14 GAK64598.1 - 2.9e-63 212.9 18.9 3.2e-63 212.8 13.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Sugar_tr PF00083.19 GAK64599.1 - 8.2e-105 350.9 28.0 9.7e-105 350.7 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK64599.1 - 3.9e-18 65.2 44.0 1.2e-16 60.3 9.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GWT1 PF06423.7 GAK64599.1 - 0.0036 17.4 3.2 0.3 11.1 0.1 3.1 2 1 1 3 3 3 2 GWT1 CAP59_mtransfer PF11735.3 GAK64600.1 - 1.1e-71 240.8 0.0 1.6e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MFS_1 PF07690.11 GAK64601.1 - 1.8e-26 92.7 33.3 2.6e-26 92.1 22.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2238 PF09997.4 GAK64601.1 - 0.34 10.2 4.5 0.24 10.8 0.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) Sulf_transp PF04143.9 GAK64602.1 - 2.8e-15 56.0 18.2 9.5e-10 38.3 4.3 4.4 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 GAK64602.1 - 6.1e-09 35.4 2.3 6.1e-09 35.4 1.6 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4341) HLH PF00010.21 GAK64603.1 - 5.1e-06 26.0 0.0 1.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CAF-1_p150 PF11600.3 GAK64603.1 - 0.02 14.2 3.2 0.035 13.4 2.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sugar_tr PF00083.19 GAK64604.1 - 1.3e-84 284.3 24.3 1.5e-84 284.1 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK64604.1 - 8.3e-16 57.6 44.5 3.3e-12 45.7 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transaldolase PF00923.14 GAK64606.1 - 1.1e-32 113.3 0.0 1.6e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Transaldolase His_Phos_2 PF00328.17 GAK64607.1 - 1.6e-31 109.9 0.0 1.9e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Exo_endo_phos PF03372.18 GAK64608.1 - 2.2e-06 27.7 0.5 2.8e-06 27.4 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rad1 PF02144.11 GAK64609.1 - 5.5e-95 317.2 0.0 6.7e-95 316.9 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF2236 PF09995.4 GAK64610.1 - 4.6e-26 91.5 4.8 7.8e-26 90.8 0.6 3.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) PriCT_2 PF08707.6 GAK64610.1 - 0.052 13.4 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) BP28CT PF08146.7 GAK64612.1 - 1.7e-37 128.4 0.3 2.3e-36 124.8 0.1 3.2 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 GAK64612.1 - 4.8e-18 65.2 5.5 4.8e-18 65.2 3.8 4.6 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.1 GAK64612.1 - 0.0022 18.4 30.2 0.019 15.4 0.0 8.9 8 0 0 8 8 8 3 HEAT-like repeat DASH_Spc19 PF08287.6 GAK64615.1 - 1e-26 93.3 4.9 1.8e-26 92.5 3.4 1.4 1 1 0 1 1 1 1 Spc19 SlyX PF04102.7 GAK64615.1 - 0.0054 17.0 5.9 2.9 8.3 0.0 3.2 3 0 0 3 3 3 2 SlyX Gp-FAR-1 PF05823.7 GAK64615.1 - 0.0069 16.3 1.9 0.14 12.1 0.0 2.2 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MscS_porin PF12795.2 GAK64615.1 - 0.0095 15.2 6.9 0.016 14.5 4.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain BRE1 PF08647.6 GAK64615.1 - 0.016 15.1 1.8 0.026 14.5 0.6 1.9 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase FUSC PF04632.7 GAK64615.1 - 0.042 12.2 9.6 0.05 12.0 6.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GPO PF05929.6 GAK64615.1 - 0.046 12.9 0.3 0.064 12.5 0.2 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Syntaxin_2 PF14523.1 GAK64615.1 - 0.066 13.2 2.6 0.14 12.1 0.5 2.5 2 1 1 3 3 3 0 Syntaxin-like protein YfcL PF08891.6 GAK64615.1 - 0.078 12.9 1.2 0.13 12.2 0.0 2.0 2 1 0 2 2 2 0 YfcL protein AAA_13 PF13166.1 GAK64615.1 - 0.093 11.1 0.5 0.13 10.6 0.3 1.3 1 1 0 1 1 1 0 AAA domain PilJ PF13675.1 GAK64615.1 - 0.22 11.8 4.6 0.33 11.2 2.4 1.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4515 PF14988.1 GAK64615.1 - 0.3 10.7 5.1 0.054 13.1 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) FlxA PF14282.1 GAK64615.1 - 0.47 10.4 3.0 0.71 9.8 0.4 2.1 2 0 0 2 2 2 0 FlxA-like protein DUF4140 PF13600.1 GAK64615.1 - 0.85 10.0 10.6 2.3 8.7 0.9 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG5 PF10392.4 GAK64615.1 - 0.95 9.4 5.9 0.51 10.2 2.3 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DivIC PF04977.10 GAK64615.1 - 1.2 8.6 7.1 2.9 7.4 0.5 2.4 2 0 0 2 2 2 0 Septum formation initiator Snapin_Pallidin PF14712.1 GAK64615.1 - 2.2 8.6 6.1 10 6.5 0.6 3.2 2 1 1 3 3 3 0 Snapin/Pallidin IncA PF04156.9 GAK64615.1 - 4.4 6.8 9.3 11 5.6 2.6 2.6 1 1 0 1 1 1 0 IncA protein GRAM PF02893.15 GAK64616.1 - 3.6e-17 61.6 0.0 7.9e-17 60.5 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Wbp11 PF09429.5 GAK64617.1 - 2.1e-11 43.6 17.1 2.1e-11 43.6 11.8 2.9 3 0 0 3 3 3 1 WW domain binding protein 11 Peptidase_C48 PF02902.14 GAK64617.1 - 8.9e-11 41.8 0.2 2.3e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain NpwBP PF12622.2 GAK64617.1 - 1.1e-10 41.8 9.9 1.1e-10 41.8 6.8 3.6 2 2 0 2 2 1 1 mRNA biogenesis factor DUF3450 PF11932.3 GAK64617.1 - 0.0043 16.3 8.1 0.0073 15.6 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Fungal_trans_2 PF11951.3 GAK64617.1 - 0.015 13.9 0.9 0.026 13.1 0.6 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain APG6 PF04111.7 GAK64617.1 - 0.32 10.0 5.2 0.5 9.3 3.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 GAK64617.1 - 0.36 10.3 7.6 0.71 9.4 5.3 1.4 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 GAK64617.1 - 1.6 8.2 7.6 2.8 7.5 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 GAK64617.1 - 2.6 5.7 4.6 3.6 5.3 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 GAK64617.1 - 4.3 6.9 11.0 8.2 6.0 7.6 1.4 1 0 0 1 1 1 0 Mnd1 family Tho2 PF11262.3 GAK64617.1 - 4.9 6.1 4.7 7.4 5.5 3.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 INCENP_ARK-bind PF03941.10 GAK64619.1 - 6.6e-07 29.0 0.1 6.6e-07 29.0 0.0 4.0 4 0 0 4 4 4 1 Inner centromere protein, ARK binding region Acyltransferase PF01553.16 GAK64621.1 - 1.3e-11 44.0 0.0 4e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Acyltransferase TTL PF03133.10 GAK64622.1 - 3.4e-46 157.5 0.0 7.5e-46 156.3 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Nro1 PF12753.2 GAK64622.1 - 0.0015 17.5 7.3 0.0022 17.0 5.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 CENP-B_dimeris PF09026.5 GAK64622.1 - 0.014 15.5 6.3 0.032 14.4 4.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Voldacs PF03517.8 GAK64622.1 - 0.082 12.7 2.1 1.5 8.6 1.5 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling ATP-grasp_4 PF13535.1 GAK64622.1 - 0.085 12.5 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Nucleoplasmin PF03066.10 GAK64622.1 - 0.25 10.8 6.5 0.41 10.1 4.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 GAK64622.1 - 0.87 8.2 7.0 1.8 7.2 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Dicty_REP PF05086.7 GAK64622.1 - 2.5 5.7 7.2 3.5 5.2 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SDA1 PF05285.7 GAK64622.1 - 3.7 6.7 6.2 5.8 6.1 4.3 1.2 1 0 0 1 1 1 0 SDA1 DUF4228 PF14009.1 GAK64623.1 - 0.13 12.3 0.2 0.13 12.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) OmpH PF03938.9 GAK64623.1 - 0.7 9.8 9.0 1.4 8.8 6.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.2 GAK64624.1 - 2e-13 50.4 0.3 2.7e-11 43.6 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAK64624.1 - 8.7e-10 37.9 0.2 0.011 15.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAK64624.1 - 1e-09 38.3 1.9 2.5e-05 24.3 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAK64624.1 - 1.2e-07 32.0 1.9 0.0013 19.1 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK64624.1 - 3.6e-06 26.6 0.8 0.2 12.0 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Nrap PF03813.9 GAK64625.1 - 6.6e-247 821.6 0.0 7.9e-247 821.4 0.0 1.0 1 0 0 1 1 1 1 Nrap protein NTP_transf_2 PF01909.18 GAK64625.1 - 0.054 13.8 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain PI31_Prot_N PF11566.3 GAK64626.1 - 4.8e-29 100.9 0.0 6.4e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 GAK64626.1 - 1.7e-08 34.9 32.2 1.7e-08 34.9 22.3 3.5 2 1 2 4 4 4 1 PI31 proteasome regulator Adaptin_N PF01602.15 GAK64627.1 - 2.9e-99 332.7 7.0 4.7e-99 332.0 4.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 GAK64627.1 - 6.9e-66 219.8 0.0 2e-65 218.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 GAK64627.1 - 5.8e-62 207.5 0.3 1.6e-61 206.1 0.1 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 GAK64627.1 - 5.2e-15 55.4 2.6 0.00025 21.2 0.0 5.0 2 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 GAK64627.1 - 1.8e-09 37.6 6.1 0.0009 19.1 0.0 4.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAK64627.1 - 5e-07 29.2 0.2 0.007 16.3 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 GAK64627.1 - 0.0013 19.1 0.1 3.4 8.2 0.0 4.7 4 1 0 4 4 3 1 HEAT-like repeat DUF3810 PF12725.2 GAK64627.1 - 0.0072 15.2 0.1 0.014 14.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Cullin PF00888.17 GAK64627.1 - 0.0098 14.4 1.4 0.087 11.3 0.1 2.2 2 0 0 2 2 2 1 Cullin family ParcG PF10274.4 GAK64627.1 - 0.013 15.3 2.9 0.47 10.3 0.0 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein Arm PF00514.18 GAK64627.1 - 0.76 9.7 4.3 84 3.2 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MutS_V PF00488.16 GAK64628.1 - 7.4e-78 261.1 0.1 1.2e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V Sec63 PF02889.11 GAK64628.1 - 2.2e-42 145.3 0.0 4.4e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain MutS_III PF05192.13 GAK64628.1 - 1.6e-38 132.5 0.1 1.6e-38 132.5 0.1 2.6 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.15 GAK64628.1 - 6.2e-34 116.4 0.0 2.4e-33 114.5 0.0 2.0 2 0 0 2 2 2 1 MutS domain I DEAD PF00270.24 GAK64628.1 - 3.2e-23 82.0 0.0 7.8e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK64628.1 - 4e-13 49.0 0.0 1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2_3 PF13878.1 GAK64628.1 - 1.7e-12 46.7 2.2 4.8e-12 45.2 1.5 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.1 GAK64628.1 - 2.2e-12 46.5 0.0 8.6e-12 44.6 0.0 2.0 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase MutS_II PF05188.12 GAK64628.1 - 3.3e-10 40.1 0.0 1.1e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 MutS domain II ResIII PF04851.10 GAK64628.1 - 7.3e-07 29.1 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MutS_IV PF05190.13 GAK64628.1 - 2.5e-06 27.5 0.0 5.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV HHH_5 PF14520.1 GAK64628.1 - 0.01 15.9 0.0 0.084 13.0 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain AAA_29 PF13555.1 GAK64628.1 - 0.091 12.3 0.1 4.6 6.8 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAK64628.1 - 0.29 11.4 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 GAK64629.1 - 1.6e-47 161.8 0.0 6.5e-47 159.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64629.1 - 3e-26 92.0 0.0 2.2e-25 89.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK64629.1 - 0.0091 14.9 0.1 0.17 10.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Enolase_C PF00113.17 GAK64630.1 - 1.4e-143 477.2 0.1 1.9e-143 476.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 GAK64630.1 - 4.5e-58 194.8 0.1 7.3e-58 194.2 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 GAK64630.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAK64630.1 - 0.0079 16.6 0.0 0.016 15.7 0.0 1.6 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 GAK64630.1 - 0.038 12.9 0.4 0.1 11.5 0.1 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus EMP24_GP25L PF01105.19 GAK64631.1 - 1.7e-40 138.6 0.1 2e-40 138.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Josephin PF02099.12 GAK64632.1 - 4.1e-53 179.2 0.1 7.4e-53 178.3 0.1 1.4 1 0 0 1 1 1 1 Josephin UIM PF02809.15 GAK64632.1 - 0.00028 20.2 30.0 0.038 13.5 0.9 4.7 5 0 0 5 5 5 3 Ubiquitin interaction motif DUF4654 PF15547.1 GAK64632.1 - 0.2 11.9 0.2 0.2 11.9 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4654) Spore_coat_CotO PF14153.1 GAK64632.1 - 7.1 6.0 9.2 17 4.8 6.4 1.7 1 0 0 1 1 1 0 Spore coat protein CotO DUF3708 PF12501.3 GAK64632.1 - 7.4 6.3 8.6 18 5.1 3.7 2.5 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter ATG27 PF09451.5 GAK64633.1 - 8.6e-79 264.5 0.0 1.2e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 ABC_tran PF00005.22 GAK64634.1 - 8e-34 116.8 0.1 2.6e-16 60.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 GAK64634.1 - 3.8e-14 51.9 5.8 3.8e-14 51.9 4.0 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 GAK64634.1 - 3.3e-13 50.2 7.0 0.0051 16.8 0.0 4.3 2 2 1 4 4 4 4 AAA domain SMC_N PF02463.14 GAK64634.1 - 4.4e-11 42.4 5.5 0.00017 20.9 0.4 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 GAK64634.1 - 1.3e-07 31.0 3.0 2 7.3 0.1 4.8 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 GAK64634.1 - 6e-07 29.6 0.0 0.00074 19.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 GAK64634.1 - 1e-05 25.7 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 GAK64634.1 - 1.9e-05 23.8 2.2 0.16 11.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAK64634.1 - 2.1e-05 23.9 0.8 0.04 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4 PF00037.22 GAK64634.1 - 4.9e-05 22.7 2.9 4.9e-05 22.7 2.0 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_17 PF13207.1 GAK64634.1 - 9.6e-05 23.1 0.7 0.8 10.5 0.2 2.8 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 GAK64634.1 - 0.00018 21.2 1.4 0.018 14.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 GAK64634.1 - 0.00024 21.5 0.0 0.4 11.2 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein AAA_16 PF13191.1 GAK64634.1 - 0.00025 21.0 0.0 0.097 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 GAK64634.1 - 0.0004 20.5 0.3 0.16 12.1 0.0 3.1 3 0 0 3 3 2 1 RNA helicase VirE PF05272.6 GAK64634.1 - 0.00042 19.8 0.0 0.39 10.1 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E AAA_33 PF13671.1 GAK64634.1 - 0.001 18.9 0.4 0.11 12.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 GAK64634.1 - 0.0011 18.6 0.9 0.34 10.6 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAK64634.1 - 0.0012 18.3 0.1 0.86 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 GAK64634.1 - 0.0022 17.7 11.0 0.007 16.1 1.5 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 GAK64634.1 - 0.0024 18.2 8.2 0.0084 16.4 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 GAK64634.1 - 0.0027 17.5 11.2 0.0061 16.3 7.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain SbcCD_C PF13558.1 GAK64634.1 - 0.003 17.4 0.0 2.2 8.2 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 GAK64634.1 - 0.0031 17.1 0.3 0.042 13.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 GAK64634.1 - 0.0056 16.1 2.8 0.23 10.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 GAK64634.1 - 0.006 16.8 3.1 1.1 9.6 0.1 3.2 2 2 1 3 3 3 1 AAA domain AAA_28 PF13521.1 GAK64634.1 - 0.0092 15.9 0.5 1.6 8.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.1 GAK64634.1 - 0.017 15.4 1.9 0.017 15.4 1.3 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAK64634.1 - 0.026 14.3 1.9 0.026 14.3 1.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 GAK64634.1 - 0.029 13.2 0.1 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 GAK64634.1 - 0.029 14.6 1.3 0.029 14.6 0.9 2.5 2 1 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 GAK64634.1 - 0.047 14.4 0.2 0.047 14.4 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_14 PF13173.1 GAK64634.1 - 0.052 13.4 1.7 13 5.6 0.0 3.4 3 1 1 4 4 3 0 AAA domain AAA_24 PF13479.1 GAK64634.1 - 0.055 13.0 0.6 0.98 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 GAK64634.1 - 0.075 12.4 0.7 4.5 6.5 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Rad17 PF03215.10 GAK64634.1 - 0.083 11.5 0.0 1.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 GAK64634.1 - 0.096 12.1 1.0 6 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain HflK_N PF12221.3 GAK64634.1 - 0.11 12.2 0.1 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal ArgK PF03308.11 GAK64634.1 - 0.16 10.7 0.2 1 8.0 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 GAK64634.1 - 0.16 11.6 1.4 2.4 7.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Fer4_8 PF13183.1 GAK64634.1 - 0.29 11.2 9.2 0.31 11.0 1.2 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 GAK64634.1 - 0.34 10.3 1.7 1.8 8.0 0.0 2.9 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 GAK64634.1 - 0.47 10.1 2.1 8.4 6.0 0.0 3.0 3 0 0 3 3 3 0 NTPase Fer4_2 PF12797.2 GAK64634.1 - 0.54 10.2 12.7 0.23 11.4 1.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain SAM_2 PF07647.12 GAK64637.1 - 1.8e-11 43.7 0.0 4.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAK64637.1 - 5.7e-07 29.6 0.2 2.6e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Mcp5_PH PF12814.2 GAK64638.1 - 1.6e-42 144.3 0.0 6.2e-42 142.3 0.0 2.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 GAK64638.1 - 9.2e-05 22.5 0.0 0.00042 20.4 0.0 2.2 2 0 0 2 2 2 1 PH domain ATG16 PF08614.6 GAK64638.1 - 0.00043 20.1 30.1 0.00043 20.1 20.8 11.3 2 2 7 10 10 10 3 Autophagy protein 16 (ATG16) HSF_DNA-bind PF00447.12 GAK64639.1 - 1.9e-35 121.1 0.1 3.7e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 GAK64639.1 - 4.6e-24 84.5 0.1 3.6e-23 81.7 0.0 2.5 3 0 0 3 3 3 1 Response regulator receiver domain RED_N PF07808.8 GAK64639.1 - 0.17 11.0 0.1 0.4 9.8 0.1 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region GCFC PF07842.7 GAK64640.1 - 2.8e-69 233.5 1.7 4e-69 233.0 1.2 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 GAK64640.1 - 9.9e-11 41.2 0.5 9.9e-11 41.2 0.4 1.9 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.3 GAK64640.1 - 1.1e-10 41.5 6.7 1.1e-10 41.5 4.6 3.5 2 1 2 4 4 4 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 GAK64640.1 - 0.00021 21.0 3.5 0.013 15.3 0.1 2.8 2 0 0 2 2 2 2 DExH-box splicing factor binding site zf-RING_2 PF13639.1 GAK64641.1 - 1.7e-11 43.7 4.8 4e-09 36.1 1.7 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 GAK64641.1 - 4.1e-10 39.6 0.8 3.4e-08 33.4 0.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAK64641.1 - 6.8e-06 25.6 2.5 3.1e-05 23.5 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK64641.1 - 1.1e-05 25.0 4.7 1.4e-05 24.6 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK64641.1 - 3.5e-05 23.7 1.5 3.5e-05 23.7 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK64641.1 - 0.00049 19.7 2.0 0.00065 19.3 0.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAK64641.1 - 0.00053 19.7 1.9 0.00074 19.3 0.6 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAK64641.1 - 0.056 13.1 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 GAK64641.1 - 0.12 11.9 2.5 0.087 12.4 0.3 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 GAK64641.1 - 0.33 10.9 2.4 0.61 10.1 1.7 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 GAK64641.1 - 0.42 10.6 3.0 0.83 9.6 0.6 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 GAK64641.1 - 1.8 8.6 6.0 0.42 10.6 1.4 1.9 2 0 0 2 2 2 0 RING-variant domain GAGA_bind PF06217.7 GAK64642.1 - 0.19 11.6 12.2 0.23 11.3 8.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 GAK64642.1 - 0.36 10.6 12.5 0.46 10.2 8.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Vfa1 PF08432.5 GAK64642.1 - 3 7.8 21.7 5.6 6.9 15.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FHA PF00498.21 GAK64643.1 - 4.2e-13 49.2 0.0 7.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 GAK64643.1 - 8.3e-08 31.9 13.7 1.3e-07 31.3 9.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAK64643.1 - 0.00019 21.4 6.8 0.00035 20.6 4.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAK64643.1 - 0.0081 15.8 12.7 0.013 15.1 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAK64643.1 - 0.013 15.3 5.0 0.023 14.5 3.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 GAK64643.1 - 0.1 12.3 11.8 0.17 11.5 8.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAK64643.1 - 0.71 9.9 14.9 1.1 9.2 10.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 GAK64643.1 - 1.1 9.0 7.9 2.1 8.1 5.5 1.4 1 0 0 1 1 1 0 PHD-finger YihI PF04220.7 GAK64643.1 - 1.6 8.0 5.8 6.6 6.0 0.6 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) ATG11 PF10377.4 GAK64644.1 - 7.3e-34 116.4 2.5 2.2e-33 114.8 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein 11 Ribosomal_L7Ae PF01248.21 GAK64645.1 - 5.1e-24 83.6 0.2 1e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 GAK64645.1 - 0.0016 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 NST1 PF13945.1 GAK64645.1 - 2.7 8.0 8.9 5.2 7.1 6.2 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Ribonuclease_P PF00825.13 GAK64646.1 - 0.0029 17.4 0.3 0.0029 17.4 0.2 1.9 2 0 0 2 2 2 1 Ribonuclease P PBP PF01161.15 GAK64648.1 - 2.8e-16 59.6 0.0 4.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.27 GAK64649.1 - 8.1e-26 88.9 19.0 6e-08 32.2 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 GAK64649.1 - 1.2e-05 23.6 0.0 0.025 12.7 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 GAK64649.1 - 0.007 15.8 0.3 0.043 13.2 0.1 2.1 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 GAK64649.1 - 0.65 10.3 4.8 46 4.4 0.0 4.3 6 0 0 6 6 6 0 PQQ-like domain Clr2 PF10383.4 GAK64651.1 - 1.5e-21 76.8 0.0 2.8e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 WW PF00397.21 GAK64651.1 - 2e-08 33.9 1.9 4.1e-08 32.9 1.3 1.6 1 0 0 1 1 1 1 WW domain DUF4611 PF15387.1 GAK64651.1 - 0.023 14.8 1.1 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-CHCC PF10276.4 GAK64651.1 - 0.18 11.6 2.2 2.5 7.9 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger domain DNA_primase_S PF01896.14 GAK64652.1 - 1.2e-52 177.5 0.0 2.3e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF928 PF06051.7 GAK64652.1 - 0.089 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Ist1 PF03398.9 GAK64653.1 - 1.4e-52 177.4 1.4 1.7e-52 177.1 1.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF3408 PF11888.3 GAK64653.1 - 3.2 7.6 6.7 7.3 6.5 4.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DnaJ PF00226.26 GAK64654.1 - 1.5e-21 75.9 1.0 4.8e-21 74.2 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain SAPS PF04499.10 GAK64654.1 - 0.024 13.3 2.7 0.033 12.8 1.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 GAK64654.1 - 3.1 7.5 4.4 5.8 6.7 3.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RrnaAD PF00398.15 GAK64655.1 - 1.2e-18 67.0 0.0 4.2e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pam17 PF08566.5 GAK64656.1 - 2.9e-69 232.2 0.0 3.6e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DEAD PF00270.24 GAK64657.1 - 4.4e-41 140.1 0.2 6.6e-41 139.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK64657.1 - 6.5e-24 83.6 0.1 1.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 GAK64657.1 - 0.0039 16.3 0.1 0.009 15.1 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF221 PF02714.10 GAK64658.1 - 1.3e-99 333.1 18.5 2.7e-99 332.1 12.8 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAK64658.1 - 2.8e-32 111.4 0.4 2.8e-32 111.4 0.3 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAK64658.1 - 4.5e-10 39.8 0.0 1.1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 GAK64658.1 - 0.16 11.9 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.16 GAK64661.1 - 2.5e-129 431.7 40.9 2.9e-129 431.5 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAK64661.1 - 5.7e-41 140.4 44.7 7.3e-41 140.0 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease IBR PF01485.16 GAK64662.1 - 4.7e-20 71.2 43.8 6.8e-12 45.0 3.0 4.5 3 1 1 4 4 4 2 IBR domain zf-RING_UBOX PF13445.1 GAK64662.1 - 0.00024 20.7 20.0 0.0018 17.9 0.5 3.7 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.1 GAK64662.1 - 0.00035 20.5 4.6 0.00035 20.5 3.2 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK64662.1 - 0.00072 19.3 5.3 0.00072 19.3 3.7 4.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 GAK64662.1 - 0.00091 18.8 5.3 0.00091 18.8 3.6 4.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) DUF1488 PF07369.6 GAK64662.1 - 0.062 13.1 0.1 1.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) zf-C3HC4_4 PF15227.1 GAK64662.1 - 0.17 11.7 25.5 0.14 12.0 0.3 4.4 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAK64662.1 - 2.2 8.0 40.7 0.067 12.9 3.8 4.3 3 1 1 4 4 4 0 zinc-RING finger domain Ribosomal_L18e PF00828.14 GAK64663.1 - 1.4e-32 112.7 0.1 2e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 FTHFS PF01268.14 GAK64664.1 - 2.6e-258 857.6 0.6 2.6e-258 857.6 0.4 1.3 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 GAK64664.1 - 4.8e-66 220.7 0.3 4.8e-66 220.7 0.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 GAK64664.1 - 2e-35 121.3 0.2 5.1e-35 120.0 0.1 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Hexapep PF00132.19 GAK64665.1 - 2.5e-11 42.5 13.3 8.6e-07 28.1 1.2 3.9 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAK64665.1 - 2.1e-05 23.9 9.8 0.017 14.7 0.2 3.1 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 GAK64665.1 - 0.017 13.6 2.5 0.26 9.8 0.2 2.3 1 1 1 2 2 2 0 L-fucokinase MPC PF03650.8 GAK64666.1 - 9.8e-40 135.2 0.2 1.1e-39 135.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ATP_transf PF09830.4 GAK64667.1 - 1.4e-14 53.5 0.0 3.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4134 PF13572.1 GAK64668.1 - 0.98 9.5 0.0 0.98 9.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) Metallophos PF00149.23 GAK64669.1 - 1.3e-08 34.4 0.0 2.6e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 GAK64670.1 - 4.8e-60 202.8 0.0 4.1e-35 121.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64670.1 - 3.2e-26 91.9 0.0 4.2e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 GAK64670.1 - 3.6e-14 53.0 1.5 2e-13 50.6 1.0 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain PX PF00787.19 GAK64670.1 - 0.056 13.2 0.1 0.38 10.5 0.0 2.4 2 1 0 2 2 2 0 PX domain Kdo PF06293.9 GAK64670.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 GAK64672.1 - 3.8e-30 103.3 0.0 3.3e-19 68.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64672.1 - 1.9e-20 72.5 0.1 3.5e-12 46.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64672.1 - 2.5e-12 46.4 0.0 0.00014 21.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 GAK64672.1 - 7.7e-10 38.3 2.0 1.3e-05 24.7 0.0 3.4 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 GAK64672.1 - 1.2e-05 24.9 0.1 0.05 13.3 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 Cytochrom_B561 PF03188.11 GAK64673.1 - 1.8e-12 47.2 8.0 1.8e-12 47.2 5.5 2.1 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF2306 PF10067.4 GAK64673.1 - 0.019 15.1 2.4 0.019 15.1 1.7 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Cytochrom_B_N PF00033.14 GAK64673.1 - 0.052 12.9 26.1 0.036 13.4 2.4 3.2 1 1 1 3 3 3 0 Cytochrome b(N-terminal)/b6/petB PepSY_TM_1 PF13172.1 GAK64673.1 - 0.075 12.8 0.2 0.075 12.8 0.1 3.0 3 1 0 3 3 3 0 PepSY-associated TM helix SecY PF00344.15 GAK64673.1 - 0.41 9.5 7.3 0.3 9.9 3.9 1.6 1 1 0 1 1 1 0 SecY translocase DUF2678 PF10856.3 GAK64673.1 - 0.77 9.5 3.3 0.3 10.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Grp1_Fun34_YaaH PF01184.14 GAK64674.1 - 8.4e-30 103.6 20.1 1.1e-29 103.2 13.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Peptidase_M17 PF00883.16 GAK64675.1 - 6.5e-111 370.1 0.0 9.7e-111 369.5 0.0 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain WD40 PF00400.27 GAK64675.1 - 5.4e-44 146.5 14.2 1.2e-09 37.6 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PFU PF09070.6 GAK64675.1 - 2.2e-43 146.9 0.2 3.9e-43 146.1 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 GAK64675.1 - 1.4e-29 102.7 0.0 7.4e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 PUL domain 5-FTHF_cyc-lig PF01812.15 GAK64676.1 - 1.2e-36 126.2 0.0 1.4e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Pribosyltran_N PF13793.1 GAK64677.1 - 1.8e-43 146.9 0.0 2.6e-42 143.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAK64677.1 - 9.6e-37 126.5 1.1 2.4e-32 112.2 0.3 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAK64677.1 - 2.7e-15 56.2 0.1 4.3e-09 36.1 0.1 3.0 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UPRTase PF14681.1 GAK64677.1 - 0.0068 15.6 0.1 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pkinase PF00069.20 GAK64678.1 - 1e-73 247.7 0.0 1.2e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64678.1 - 2.4e-34 118.5 0.0 6.1e-34 117.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK64678.1 - 0.00025 20.1 0.0 0.00058 18.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK64678.1 - 0.0055 15.7 0.1 0.014 14.5 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAK64678.1 - 0.0056 16.4 0.1 0.017 14.8 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.4 GAK64678.1 - 0.078 11.5 0.0 0.098 11.2 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.6 GAK64678.1 - 0.084 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SGT1 PF07093.6 GAK64679.1 - 0.19 10.0 5.7 0.24 9.7 3.9 1.0 1 0 0 1 1 1 0 SGT1 protein Spc97_Spc98 PF04130.8 GAK64680.1 - 3.1e-48 164.4 0.0 4.9e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF4050 PF13259.1 GAK64680.1 - 0.058 13.3 0.1 0.058 13.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) PIG-S PF10510.4 GAK64680.1 - 0.54 8.8 6.3 0.41 9.2 0.4 2.8 2 1 1 3 3 3 0 Phosphatidylinositol-glycan biosynthesis class S protein MOZ_SAS PF01853.13 GAK64681.1 - 9.4e-79 263.0 0.1 1.4e-78 262.4 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 GAK64681.1 - 1.3e-16 60.0 24.3 1.1e-09 37.8 6.1 3.2 2 1 1 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 GAK64681.1 - 5.2 6.3 15.3 0.81 8.9 3.4 2.8 2 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain SAPS PF04499.10 GAK64682.1 - 1.6e-170 567.8 0.0 1.3e-169 564.8 0.0 2.3 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein DUF342 PF03961.8 GAK64682.1 - 0.41 9.0 1.5 0.66 8.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 GAK64682.1 - 0.84 7.4 0.1 1.3 6.8 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ycf1 PF05758.7 GAK64682.1 - 0.91 7.1 0.2 1.3 6.6 0.1 1.1 1 0 0 1 1 1 0 Ycf1 Profilin PF00235.14 GAK64683.1 - 9.1e-37 125.8 0.1 1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Profilin TIM PF00121.13 GAK64684.1 - 3.7e-96 320.9 1.0 4.4e-96 320.6 0.7 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 GAK64684.1 - 0.00012 21.3 0.1 0.00064 19.0 0.0 1.9 1 1 1 2 2 2 1 CutC family Thiolase_N PF00108.18 GAK64685.1 - 3.5e-82 275.3 0.8 3.5e-82 275.3 0.6 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAK64685.1 - 2.1e-48 162.8 0.4 2.1e-48 162.8 0.3 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAK64685.1 - 1.8e-05 24.3 1.1 5.7e-05 22.7 0.8 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain bZIP_1 PF00170.16 GAK64686.1 - 0.00043 20.1 14.2 0.00075 19.4 9.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor Ribosomal_L27e PF01777.13 GAK64686.1 - 0.16 12.1 1.3 0.3 11.2 0.9 1.4 1 0 0 1 1 1 0 Ribosomal L27e protein family bZIP_Maf PF03131.12 GAK64686.1 - 0.67 10.2 12.2 1.1 9.5 8.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 GAK64686.1 - 1.6 6.5 2.2 2.2 6.0 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_S21 PF01165.15 GAK64687.1 - 0.031 13.7 0.4 0.061 12.7 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 Peptidase_M30 PF10460.4 GAK64687.1 - 0.53 9.0 2.4 0.86 8.4 1.7 1.2 1 0 0 1 1 1 0 Peptidase M30 HAD PF12710.2 GAK64689.1 - 3.2e-13 50.2 0.0 1.9e-12 47.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK64689.1 - 3.5e-11 42.9 0.0 2.5e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 GAK64689.1 - 4.6e-11 42.1 0.0 1.2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAK64689.1 - 1e-10 42.3 1.9 1.4e-05 25.6 0.1 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAK64689.1 - 0.00031 20.4 0.5 0.007 15.9 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tmemb_cc2 PF10267.4 GAK64689.1 - 0.028 13.0 0.0 0.073 11.6 0.0 1.6 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein zf-UBR PF02207.15 GAK64690.1 - 2.3e-12 46.4 8.2 2.3e-12 46.4 5.7 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 GAK64690.1 - 0.00011 21.8 1.4 0.00011 21.8 1.0 3.7 4 1 0 4 4 4 1 PHD-finger Pyrid_oxidase_2 PF13883.1 GAK64691.1 - 1.2e-23 83.7 0.1 1.6e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rad51 PF08423.6 GAK64692.1 - 3.8e-138 458.5 0.1 4.6e-138 458.2 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAK64692.1 - 3.4e-15 55.9 0.0 4.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 GAK64692.1 - 1.2e-08 34.4 0.1 1.7e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 GAK64692.1 - 1.9e-08 34.3 0.2 4.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 GAK64692.1 - 2.2e-07 30.2 0.0 3.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 GAK64692.1 - 0.026 13.4 0.0 0.073 11.9 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 GAK64692.1 - 0.048 12.4 1.0 0.17 10.7 0.4 1.8 1 1 1 2 2 2 0 PAXNEB protein HHH PF00633.18 GAK64692.1 - 0.062 13.0 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PNRC PF15365.1 GAK64693.1 - 7.5e-08 32.2 1.0 7.5e-08 32.2 0.7 3.2 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator CBFD_NFYB_HMF PF00808.18 GAK64694.1 - 1.5e-09 37.7 0.1 2.7e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VRR_NUC PF08774.6 GAK64695.1 - 9.6e-20 70.4 0.0 2.6e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain SAP PF02037.22 GAK64695.1 - 0.046 13.2 0.2 0.24 10.9 0.0 2.4 2 0 0 2 2 2 0 SAP domain Rho_N PF07498.7 GAK64695.1 - 0.092 12.5 0.1 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Myosin_head PF00063.16 GAK64696.1 - 1.8e-250 832.7 0.0 1.8e-250 832.7 0.0 3.6 2 1 2 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 GAK64696.1 - 5e-14 51.0 70.8 5e-14 51.0 49.1 5.3 3 1 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 GAK64696.1 - 8.9e-07 28.4 0.1 2e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 GAK64696.1 - 0.0054 16.4 0.1 0.028 14.1 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAK64696.1 - 0.18 11.9 0.0 0.18 11.9 0.0 4.8 5 0 0 5 5 5 0 AAA domain RabGAP-TBC PF00566.13 GAK64697.1 - 5.9e-18 65.1 0.0 1.4e-10 40.9 0.1 3.3 3 0 0 3 3 3 3 Rab-GTPase-TBC domain Chromo PF00385.19 GAK64698.1 - 2e-13 49.7 2.5 2e-13 49.7 1.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 GAK64698.1 - 5e-08 32.6 1.3 1.3e-06 28.1 0.0 2.9 3 1 0 3 3 3 1 Chromo shadow domain PBP1_TM PF14812.1 GAK64698.1 - 2.9e-05 24.3 6.3 2.9e-05 24.3 4.3 4.2 3 1 1 4 4 4 2 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3759 PF12585.3 GAK64699.1 - 2.5e-35 120.2 6.9 2.9e-35 120.0 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF4149 PF13664.1 GAK64700.1 - 0.17 11.9 3.6 0.26 11.3 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) PfkB PF00294.19 GAK64701.1 - 3.8e-08 32.8 0.0 0.00026 20.2 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase WD40 PF00400.27 GAK64703.1 - 3.7e-66 216.8 18.9 6.2e-11 41.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 GAK64703.1 - 2.1e-27 95.1 4.6 3.6e-27 94.3 3.2 1.4 1 0 0 1 1 1 1 Tup N-terminal Nucleoporin_N PF08801.6 GAK64703.1 - 3e-05 22.9 0.9 0.073 11.8 0.1 3.0 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 GAK64703.1 - 0.00011 20.5 3.2 0.93 7.5 0.0 3.5 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 GAK64703.1 - 0.00069 18.0 0.2 0.5 8.5 0.0 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 GAK64703.1 - 0.0013 17.8 0.2 1.1 8.2 0.0 3.7 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Striatin PF08232.7 GAK64703.1 - 0.0069 16.7 0.2 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Striatin family PQQ_2 PF13360.1 GAK64703.1 - 0.011 15.1 1.1 0.057 12.8 0.5 2.2 1 1 1 2 2 2 0 PQQ-like domain DUF812 PF05667.6 GAK64703.1 - 0.094 11.2 0.5 0.14 10.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3450 PF11932.3 GAK64703.1 - 0.17 11.1 1.2 0.29 10.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Bystin PF05291.6 GAK64704.1 - 3.2e-133 443.3 0.0 4.3e-133 442.8 0.0 1.1 1 0 0 1 1 1 1 Bystin GPP34 PF05719.6 GAK64705.1 - 3.7e-72 242.6 0.0 4.7e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) POP1 PF06978.6 GAK64706.1 - 3.2e-41 141.0 17.7 3.2e-41 141.0 12.3 3.5 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 GAK64706.1 - 2.1e-08 33.9 4.6 4.6e-08 32.7 0.5 3.0 2 1 0 2 2 2 1 POPLD (NUC188) domain Sec20 PF03908.8 GAK64707.1 - 0.094 12.4 1.0 0.21 11.3 0.7 1.5 1 0 0 1 1 1 0 Sec20 UreE_N PF02814.10 GAK64707.1 - 0.12 11.8 0.3 0.35 10.3 0.1 1.8 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain SRP40_C PF05022.7 GAK64708.1 - 8.5e-29 99.8 1.3 1.9e-28 98.7 0.9 1.6 1 0 0 1 1 1 1 SRP40, C-terminal domain adh_short PF00106.20 GAK64709.1 - 1.7e-22 80.1 0.3 2.4e-22 79.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK64709.1 - 1.3e-09 37.9 0.4 3.7e-09 36.4 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAK64709.1 - 0.11 11.9 0.1 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Med15 PF09606.5 GAK64710.1 - 0.03 12.5 124.1 0.05 11.8 86.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kelch_4 PF13418.1 GAK64711.1 - 3.7e-43 145.0 14.0 1e-07 31.5 0.1 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAK64711.1 - 9.7e-41 137.0 6.6 3.4e-09 36.6 0.1 6.9 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 GAK64711.1 - 2.9e-32 109.9 0.3 1.7e-05 24.2 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 GAK64711.1 - 1.1e-29 101.8 4.4 9.5e-06 25.4 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAK64711.1 - 4.5e-28 95.9 10.3 9.4e-07 28.3 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAK64711.1 - 5.4e-26 89.6 9.4 2.7e-05 24.1 0.0 6.5 4 1 2 6 6 6 5 Kelch motif PQQ_3 PF13570.1 GAK64711.1 - 0.012 15.8 0.5 2.6 8.4 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain Adaptin_N PF01602.15 GAK64712.1 - 3.7e-98 329.1 1.4 2.1e-84 283.7 1.5 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 GAK64712.1 - 1e-06 28.8 16.2 4.9e-05 23.5 0.3 6.3 5 1 1 6 6 6 2 HEAT repeats Cnd1 PF12717.2 GAK64712.1 - 0.00032 20.6 0.1 0.0035 17.1 0.0 2.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAK64712.1 - 0.0042 17.0 9.9 1.8 8.8 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat PPP4R2 PF09184.6 GAK64712.1 - 4 6.9 17.4 7.5 6.0 12.0 1.5 1 0 0 1 1 1 0 PPP4R2 DUF4189 PF13827.1 GAK64713.1 - 0.064 13.5 0.1 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4189) Gar1 PF04410.9 GAK64714.1 - 1.2e-31 109.2 0.0 1.2e-31 109.2 0.0 2.9 3 1 0 3 3 3 1 Gar1/Naf1 RNA binding region zf-AN1 PF01428.11 GAK64714.1 - 2e-14 53.1 18.2 2.8e-09 36.6 2.3 3.0 3 0 0 3 3 3 2 AN1-like Zinc finger Unstab_antitox PF09720.5 GAK64714.1 - 0.035 13.7 1.2 0.12 12.1 0.9 1.9 1 0 0 1 1 1 0 Putative addiction module component Nucleo_P87 PF07267.6 GAK64714.1 - 0.21 10.2 9.4 0.43 9.2 6.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Malate_synthase PF01274.17 GAK64715.1 - 4.9e-208 691.3 0.0 6.4e-208 690.9 0.0 1.1 1 0 0 1 1 1 1 Malate synthase Thioredoxin PF00085.15 GAK64715.1 - 1.8e-25 88.6 0.1 3.5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAK64715.1 - 7.3e-06 26.1 0.1 3.3e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAK64715.1 - 2.4e-05 24.3 0.0 0.00039 20.4 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 GAK64715.1 - 0.0013 18.3 0.1 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 GAK64715.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 GAK64715.1 - 0.004 16.8 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAK64715.1 - 0.011 15.2 0.2 0.38 10.3 0.0 2.3 1 1 1 2 2 2 0 Redoxin Bromodomain PF00439.20 GAK64715.1 - 0.059 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain HATPase_c PF02518.21 GAK64716.1 - 2e-29 101.5 0.1 1.8e-28 98.4 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAK64716.1 - 1.2e-25 89.6 0.1 4.6e-25 87.7 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.5 GAK64716.1 - 2.8e-21 75.6 3.2 1.7e-06 27.9 0.0 4.5 4 0 0 4 4 4 3 PAS fold HisKA PF00512.20 GAK64716.1 - 4.2e-19 68.3 0.1 1.3e-18 66.7 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 GAK64716.1 - 7.1e-15 55.2 0.0 4.9e-08 33.2 0.0 4.6 4 1 0 4 4 4 2 PAS domain PAS_3 PF08447.6 GAK64716.1 - 3.6e-13 49.4 2.8 3.6e-13 49.4 2.0 2.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 GAK64716.1 - 9.3e-12 44.7 1.0 0.0013 18.5 0.0 5.0 5 0 0 5 5 5 2 PAS fold PAS_8 PF13188.1 GAK64716.1 - 0.00036 20.2 0.0 4.1 7.4 0.0 4.0 4 0 0 4 4 4 2 PAS domain HATPase_c_3 PF13589.1 GAK64716.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_11 PF14598.1 GAK64716.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain DEAD PF00270.24 GAK64717.1 - 9.3e-40 135.8 0.0 1.1e-20 73.8 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF4217 PF13959.1 GAK64717.1 - 3e-21 74.7 0.0 8.3e-21 73.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 GAK64717.1 - 2.4e-18 65.7 0.0 6.2e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK64717.1 - 1.9e-06 27.8 2.1 2e-06 27.7 0.0 2.1 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 GAK64717.1 - 0.0094 15.2 4.7 0.089 12.0 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 GAK64717.1 - 0.016 14.9 0.0 0.063 13.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 GAK64717.1 - 0.055 13.6 0.0 0.48 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain SPX PF03105.14 GAK64718.1 - 3e-28 99.3 1.5 2.5e-26 93.1 1.1 2.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 GAK64718.1 - 6.7e-08 32.0 5.7 1.1e-07 31.3 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK64718.1 - 1.5e-06 27.8 8.6 2.5e-06 27.1 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAK64718.1 - 1.8e-06 27.7 6.4 3e-06 27.0 4.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 GAK64718.1 - 2.2e-06 27.2 4.6 3.7e-06 26.5 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK64718.1 - 8.4e-06 25.7 7.8 1.4e-05 25.0 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK64718.1 - 0.00014 21.5 5.6 0.00026 20.6 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAK64718.1 - 0.0042 16.7 4.1 0.011 15.3 2.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 GAK64718.1 - 0.0058 16.3 2.6 0.014 15.1 1.8 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 GAK64718.1 - 0.0074 15.8 2.0 0.015 14.8 1.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Psu PF07455.6 GAK64718.1 - 0.036 13.5 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) zf-rbx1 PF12678.2 GAK64718.1 - 0.41 10.7 5.6 1.3 9.1 3.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger GMC_oxred_N PF00732.14 GAK64719.1 - 6.7e-48 163.3 0.0 1e-47 162.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK64719.1 - 3.6e-40 137.5 0.1 5.7e-40 136.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAK64719.1 - 0.00026 20.9 0.1 0.0007 19.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK64719.1 - 0.00046 19.1 0.1 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK64719.1 - 0.0015 17.4 0.1 0.0027 16.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAK64719.1 - 0.0041 17.2 0.2 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK64719.1 - 0.0094 14.9 0.1 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAK64719.1 - 0.0096 15.0 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAK64719.1 - 0.13 10.7 0.2 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein COG5 PF10392.4 GAK64720.1 - 6.1e-19 68.2 3.4 1.5e-16 60.5 1.7 3.1 2 0 0 2 2 2 2 Golgi transport complex subunit 5 IncA PF04156.9 GAK64720.1 - 0.029 13.9 4.0 0.076 12.6 2.8 1.6 1 0 0 1 1 1 0 IncA protein dCMP_cyt_deam_1 PF00383.17 GAK64721.1 - 7.6e-25 86.5 2.3 1.3e-24 85.7 1.6 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_33 PF13671.1 GAK64721.1 - 8.7e-05 22.4 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK64721.1 - 0.00018 22.3 0.0 0.00045 21.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAK64721.1 - 0.018 15.3 0.0 0.055 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 GAK64721.1 - 0.02 15.1 0.1 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 GAK64721.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain APOBEC_N PF08210.6 GAK64721.1 - 0.12 11.9 0.8 0.21 11.1 0.5 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain AAA_5 PF07728.9 GAK64721.1 - 0.15 11.7 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TFIIIC_sub6 PF10419.4 GAK64723.1 - 6e-09 35.2 0.0 1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit Rpn3_C PF08375.6 GAK64724.1 - 5.7e-26 90.7 0.6 2.7e-25 88.5 0.4 2.2 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 GAK64724.1 - 7.5e-17 61.5 0.2 2e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 PCI domain NT-C2 PF10358.4 GAK64724.1 - 3.4e-09 36.3 0.0 0.017 14.5 0.0 3.7 3 1 0 3 3 3 3 N-terminal C2 in EEIG1 and EHBP1 proteins PH_9 PF15410.1 GAK64725.1 - 1.7e-08 34.6 0.1 8.8e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAK64725.1 - 2.1e-07 31.1 0.0 4.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAK64725.1 - 0.013 15.7 0.2 0.12 12.6 0.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Bestrophin PF01062.16 GAK64726.1 - 2e-21 76.1 0.1 8.4e-12 44.6 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel NUDIX PF00293.23 GAK64727.1 - 3.6e-08 33.1 0.0 5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Peptidase_M16 PF00675.15 GAK64728.1 - 3.4e-44 150.1 1.3 2.3e-41 140.9 0.0 3.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAK64728.1 - 4.4e-30 104.7 0.1 5.5e-20 71.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Aa_trans PF01490.13 GAK64728.1 - 2.4e-26 92.1 37.2 2.4e-26 92.1 25.8 1.5 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein S1-like PF14444.1 GAK64728.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 S1-like DUF2061 PF09834.4 GAK64728.1 - 0.41 10.8 9.1 0.13 12.5 0.3 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) tRNA-synt_1b PF00579.20 GAK64729.1 - 2.2e-73 246.9 0.0 3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FimP PF09766.4 GAK64730.1 - 2.5e-28 99.1 15.6 3.4e-28 98.7 10.8 1.1 1 0 0 1 1 1 1 Fms-interacting protein Ribosomal_L25p PF01386.14 GAK64730.1 - 0.086 12.9 0.4 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L25p family BAR_2 PF10455.4 GAK64730.1 - 1.6 7.5 10.9 3.2 6.5 7.5 1.6 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking AAA_23 PF13476.1 GAK64730.1 - 2.1 8.6 9.3 2.9 8.1 6.4 1.2 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.6 GAK64730.1 - 3.8 6.0 10.2 0.56 8.8 2.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) Afi1 PF07792.7 GAK64731.1 - 5.8e-41 139.8 0.0 1e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 GAK64731.1 - 1.4e-32 111.6 0.0 2.8e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAK64731.1 - 3.2e-08 32.4 0.0 0.018 13.5 0.0 3.7 3 2 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 GAK64731.1 - 0.001 18.4 0.0 0.39 9.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Peptidase_C50 PF03568.12 GAK64733.1 - 6e-81 272.0 0.0 1.7e-79 267.2 0.0 2.8 1 1 0 1 1 1 1 Peptidase family C50 TPR_7 PF13176.1 GAK64733.1 - 0.0015 18.1 0.2 0.8 9.6 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAK64733.1 - 0.56 10.7 10.3 0.67 10.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SNF2_N PF00176.18 GAK64734.1 - 1.6e-70 237.2 0.1 2.6e-70 236.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK64734.1 - 3.6e-12 45.9 0.0 7.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK64734.1 - 3.8e-09 36.6 0.0 1.4e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAK64734.1 - 4.9e-09 35.8 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 GAK64734.1 - 4.8e-07 29.3 5.5 4.8e-07 29.3 3.8 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK64734.1 - 1.4e-06 28.1 6.3 1.4e-06 28.1 4.3 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK64734.1 - 6.5e-06 25.7 6.4 6.5e-06 25.7 4.4 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK64734.1 - 4e-05 23.3 8.2 4e-05 23.3 5.7 2.6 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 GAK64734.1 - 0.00014 21.4 6.6 0.00014 21.4 4.6 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAK64734.1 - 0.0087 15.7 1.1 0.025 14.2 0.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 GAK64734.1 - 0.043 13.6 2.6 0.1 12.3 1.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 GAK64734.1 - 0.056 12.9 13.0 0.081 12.4 1.0 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Ald_Xan_dh_C2 PF02738.13 GAK64735.1 - 2.1e-186 620.4 0.1 2.8e-186 620.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 GAK64735.1 - 1.2e-38 132.2 0.0 3.9e-38 130.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 GAK64735.1 - 4.8e-35 119.9 0.1 1e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 GAK64735.1 - 6.6e-27 93.4 0.0 1.6e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 GAK64735.1 - 3.8e-25 87.5 0.1 1.3e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.22 GAK64735.1 - 1.6e-06 27.7 0.0 5.1e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Velvet PF11754.3 GAK64736.1 - 3.1e-24 85.7 0.6 8.2e-24 84.3 0.4 1.7 1 1 0 1 1 1 1 Velvet factor RXT2_N PF08595.6 GAK64737.1 - 0.4 10.4 4.2 0.74 9.6 2.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 GAK64737.1 - 4.6 6.4 6.1 8.3 5.5 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein Lgl_C PF08596.5 GAK64738.1 - 5.6e-23 81.0 0.0 2.5e-18 65.7 0.0 2.4 2 1 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 GAK64738.1 - 0.00014 21.6 0.6 0.0083 15.9 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF3312 PF11768.3 GAK64738.1 - 0.8 7.8 0.0 5.2 5.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Glyco_transf_20 PF00982.16 GAK64739.1 - 1.6e-152 508.3 0.0 2.6e-152 507.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAK64739.1 - 1.5e-68 230.2 0.0 2.7e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase ING PF12998.2 GAK64740.1 - 1.6e-14 54.0 0.0 6.9e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 GAK64740.1 - 1.2e-07 31.3 8.0 2e-07 30.5 5.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAK64740.1 - 0.022 14.0 1.4 0.038 13.2 1.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 GAK64740.1 - 0.45 10.5 5.8 0.69 9.9 4.0 1.3 1 0 0 1 1 1 0 RING-like domain SMC_N PF02463.14 GAK64741.1 - 2.6e-64 216.4 0.0 2.3e-63 213.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAK64741.1 - 2e-30 105.2 0.5 7.3e-30 103.4 0.1 2.2 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAK64741.1 - 1.8e-14 54.4 2.4 7.6e-09 35.9 1.3 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAK64741.1 - 1.7e-08 33.8 0.0 4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 GAK64741.1 - 2.2e-07 30.3 16.5 0.0053 15.9 0.2 5.1 5 0 0 5 5 5 2 Reovirus sigma C capsid protein AAA_15 PF13175.1 GAK64741.1 - 5.3e-06 25.7 2.7 0.00057 19.0 0.1 3.5 3 1 0 3 3 3 1 AAA ATPase domain IncA PF04156.9 GAK64741.1 - 0.0001 21.9 6.7 0.0001 21.9 4.6 7.2 4 2 1 7 7 6 3 IncA protein SbcCD_C PF13558.1 GAK64741.1 - 0.0012 18.7 0.0 0.0045 16.8 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit WEMBL PF05701.6 GAK64741.1 - 0.0018 16.8 1.1 0.0018 16.8 0.8 5.4 3 2 1 5 5 5 2 Weak chloroplast movement under blue light DUF3584 PF12128.3 GAK64741.1 - 0.0046 14.3 98.4 0.0051 14.2 24.5 3.0 2 2 1 3 3 3 2 Protein of unknown function (DUF3584) AAA_23 PF13476.1 GAK64741.1 - 0.015 15.6 82.2 0.06 13.6 34.6 5.7 3 2 0 3 3 2 0 AAA domain TetR_C_5 PF08360.6 GAK64741.1 - 0.023 14.6 0.1 0.29 11.0 0.0 2.5 2 0 0 2 2 2 0 QacR-like protein, C-terminal region Clavanin PF05452.6 GAK64741.1 - 0.13 12.3 0.1 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Clavanin NPV_P10 PF05531.7 GAK64741.1 - 0.15 12.3 23.8 13 6.1 0.1 6.8 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 GAK64741.1 - 2.5 6.4 71.4 0.025 13.0 15.4 6.3 4 2 1 5 5 4 0 AAA domain DUF3530 PF12048.3 GAK64742.1 - 0.019 13.9 3.0 0.037 13.0 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) KH_1 PF00013.24 GAK64743.1 - 6e-06 25.8 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 GAK64743.1 - 7.6e-05 22.2 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 GAK64743.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 KH domain CT47 PF15623.1 GAK64743.1 - 8.1 6.0 15.8 11 5.6 10.9 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 GRAB PF10375.4 GAK64744.1 - 9.4e-07 28.2 4.5 1.5e-06 27.5 0.3 2.4 2 0 0 2 2 2 1 GRIP-related Arf-binding domain SlyX PF04102.7 GAK64744.1 - 0.026 14.8 1.1 0.026 14.8 0.8 5.3 3 2 2 6 6 5 0 SlyX bZIP_1 PF00170.16 GAK64744.1 - 0.039 13.9 0.2 0.039 13.9 0.2 4.1 4 0 0 4 4 4 0 bZIP transcription factor IFT57 PF10498.4 GAK64744.1 - 0.12 11.0 19.0 1.3 7.6 7.0 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 GAK64744.1 - 0.21 10.7 14.9 0.7 9.0 3.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 GAK64744.1 - 0.34 10.4 18.9 0.028 13.9 2.7 3.3 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 GAK64744.1 - 0.39 10.9 3.6 7.5 6.8 0.4 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 GAK64744.1 - 0.4 11.0 0.1 0.4 11.0 0.0 4.9 4 1 0 4 4 3 0 Protein of unknown function (DUF904) Atg14 PF10186.4 GAK64744.1 - 0.9 8.4 32.5 0.15 10.9 11.3 2.7 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 GAK64744.1 - 4.4 7.1 33.1 0.76 9.6 1.2 5.2 3 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 GAK64744.1 - 6.3 6.6 7.6 3.7 7.3 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 GAK64744.1 - 6.6 5.2 23.9 0.057 12.0 5.3 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.6 GAK64744.1 - 8.1 6.3 17.1 4 7.3 1.0 3.7 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TPP_enzyme_N PF02776.13 GAK64745.1 - 3.7e-54 182.7 5.3 5.4e-54 182.2 0.0 3.2 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAK64745.1 - 1.7e-48 164.0 0.1 6.5e-47 158.9 0.0 2.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAK64745.1 - 8.3e-37 126.0 2.3 2e-36 124.7 0.1 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Med3 PF11593.3 GAK64745.1 - 0.069 12.3 5.0 0.11 11.7 3.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CO_dh PF02552.11 GAK64745.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Dor1 PF04124.7 GAK64746.1 - 3.9e-18 65.0 3.1 3.5e-14 52.0 1.5 2.7 2 1 0 2 2 2 2 Dor1-like family Ribosomal_S10 PF00338.17 GAK64747.1 - 2.2e-32 110.7 0.5 2.7e-32 110.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribophorin_II PF05817.9 GAK64748.1 - 1.2e-05 23.7 0.3 0.00024 19.4 0.2 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II BTB PF00651.26 GAK64749.1 - 4.4e-13 49.1 0.0 3.2e-10 39.9 0.0 3.4 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.20 GAK64749.1 - 8e-07 28.6 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Pkinase PF00069.20 GAK64750.1 - 2e-68 230.3 0.0 2.7e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64750.1 - 1.4e-41 142.3 0.0 2e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 GAK64750.1 - 3e-30 103.9 0.0 4.7e-15 55.2 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 GAK64750.1 - 3.4e-07 29.5 0.0 1.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 GAK64750.1 - 0.0017 17.9 0.0 0.55 9.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) Kdo PF06293.9 GAK64750.1 - 0.089 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BBS2_Mid PF14783.1 GAK64750.1 - 0.14 11.9 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Aldo_ket_red PF00248.16 GAK64751.1 - 1.1e-42 145.7 0.0 1.3e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.17 GAK64752.1 - 9.9e-17 60.3 0.0 2e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64752.1 - 9.5e-14 51.1 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64752.1 - 1.6e-07 31.0 0.0 3.4e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAK64752.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_PEP_C PF04513.7 GAK64753.1 - 0.072 12.9 9.2 2 8.2 2.0 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus E1-E2_ATPase PF00122.15 GAK64756.1 - 6e-16 58.1 0.1 1.3e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 GAK64756.1 - 4.4e-15 56.3 0.0 1.8e-13 51.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAK64756.1 - 1.7e-12 48.2 3.7 2.8e-10 40.9 2.5 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK64756.1 - 2.4e-11 43.4 0.0 5.8e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAK64756.1 - 0.0014 18.2 0.2 0.0092 15.5 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase adh_short PF00106.20 GAK64757.1 - 1.2e-09 38.3 6.8 2e-09 37.5 0.6 2.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK64757.1 - 0.00081 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAK64757.1 - 0.0053 16.2 0.2 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAK64757.1 - 0.0053 16.4 2.7 0.041 13.5 1.9 2.1 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 GAK64757.1 - 0.1 11.6 0.2 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.19 GAK64760.1 - 4.8e-40 137.5 1.0 7e-40 137.0 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK64760.1 - 5.1e-05 23.0 0.1 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAK64760.1 - 0.0021 18.1 0.0 0.59 10.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK64760.1 - 0.0055 16.6 0.4 0.021 14.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK64760.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK64760.1 - 0.065 12.1 0.1 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 GAK64760.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ECH PF00378.15 GAK64761.1 - 9.5e-25 87.1 0.3 1.2e-24 86.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Lumazine_bd PF12870.2 GAK64761.1 - 0.12 12.4 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Lumazine-binding domain Ctr PF04145.10 GAK64762.1 - 3.6e-34 117.8 0.8 4.2e-34 117.6 0.5 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Bromodomain PF00439.20 GAK64763.1 - 2.2e-36 123.6 0.6 1.3e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 Bromodomain Med15 PF09606.5 GAK64763.1 - 5.3e-05 21.6 66.2 5.3e-05 21.6 45.9 3.0 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal V_ATPase_I PF01496.14 GAK64763.1 - 2.3 5.9 13.8 3.3 5.4 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 GAK64763.1 - 8 4.9 4.4 12 4.3 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SCAMP PF04144.8 GAK64764.1 - 1.8e-50 171.2 4.0 2.2e-50 171.0 2.8 1.0 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.3 GAK64764.1 - 0.065 12.4 0.9 0.1 11.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1700 PF08006.6 GAK64764.1 - 0.5 9.6 2.7 0.9 8.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Septin PF00735.13 GAK64765.1 - 5.8e-113 376.5 1.1 7.2e-113 376.2 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 GAK64765.1 - 2.7e-08 33.7 0.0 1.3e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAK64765.1 - 2.9e-06 26.5 0.0 5.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAK64765.1 - 2.1e-05 24.4 0.4 0.052 13.3 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 GAK64765.1 - 2.5e-05 23.4 0.4 6.1e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 GAK64765.1 - 0.00024 20.6 0.3 0.0017 17.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 GAK64765.1 - 0.00025 20.5 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 GAK64765.1 - 0.00066 19.2 0.1 0.00066 19.2 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 GAK64765.1 - 0.0014 17.6 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IIGP PF05049.8 GAK64765.1 - 0.0014 17.5 0.0 0.0032 16.3 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 GAK64765.1 - 0.0015 18.8 0.3 0.0053 17.0 0.0 2.0 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 GAK64765.1 - 0.0025 18.3 0.2 0.026 15.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 GAK64765.1 - 0.0054 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 GAK64765.1 - 0.017 13.9 0.2 0.032 13.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 GAK64765.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 GAK64765.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 GAK64765.1 - 0.023 13.8 0.1 0.075 12.1 0.1 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAK64765.1 - 0.023 14.8 0.0 0.073 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAK64765.1 - 0.048 14.4 0.8 2.2 9.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 GAK64765.1 - 0.05 13.2 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 GAK64765.1 - 0.054 13.8 0.6 0.25 11.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAK64765.1 - 0.064 13.1 1.4 0.51 10.2 0.0 2.7 3 1 0 3 3 2 0 AAA domain Ras PF00071.17 GAK64765.1 - 0.073 12.4 0.1 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Ras family DUF87 PF01935.12 GAK64765.1 - 0.081 12.7 0.5 0.64 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 FAT PF02259.18 GAK64766.1 - 9.9e-125 416.1 2.8 9.9e-125 416.1 1.9 2.5 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 GAK64766.1 - 4e-56 190.1 0.1 7.2e-56 189.2 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 GAK64766.1 - 3.1e-52 176.7 0.1 4.1e-51 173.0 0.0 3.1 3 1 1 4 4 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 GAK64766.1 - 1.1e-40 137.7 0.2 1.1e-40 137.7 0.1 3.2 3 1 1 4 4 3 1 Rapamycin binding domain HEAT_2 PF13646.1 GAK64766.1 - 5.2e-22 77.9 11.8 0.00039 20.6 0.0 12.1 8 2 4 12 12 11 5 HEAT repeats FATC PF02260.15 GAK64766.1 - 1.7e-12 46.5 0.1 3.8e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 GAK64766.1 - 2.2e-11 42.8 11.0 0.51 10.5 0.1 11.1 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.1 GAK64766.1 - 6.8e-06 26.4 21.9 2.6 8.6 0.1 12.4 12 2 3 15 15 12 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAK64766.1 - 1.9e-05 24.9 0.1 15 6.0 0.0 6.0 6 1 0 6 6 4 0 Vacuolar 14 Fab1-binding region TPR_19 PF14559.1 GAK64766.1 - 0.00064 20.0 0.2 12 6.3 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat VHS PF00790.14 GAK64766.1 - 0.015 14.9 0.1 0.98 9.0 0.0 3.6 4 0 0 4 4 3 0 VHS domain TPR_11 PF13414.1 GAK64766.1 - 0.015 14.8 8.0 5.7 6.6 0.0 5.5 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.23 GAK64766.1 - 0.025 14.1 0.7 17 5.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Cnd1 PF12717.2 GAK64766.1 - 0.041 13.7 2.0 2 8.2 0.1 4.4 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 TSA PF03249.8 GAK64766.1 - 0.064 11.7 0.3 0.14 10.7 0.2 1.5 1 0 0 1 1 1 0 Type specific antigen TPR_7 PF13176.1 GAK64766.1 - 0.11 12.3 1.7 36 4.4 0.0 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.15 GAK64766.1 - 0.18 10.0 6.7 2.9 6.0 0.1 4.0 3 1 1 4 4 4 0 Adaptin N terminal region Sporozoite_P67 PF05642.6 GAK64766.1 - 2.5 5.8 0.1 3.9 5.2 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_2 PF07719.12 GAK64766.1 - 2.6 8.1 10.8 4.1 7.5 0.2 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat DHO_dh PF01180.16 GAK64767.1 - 2.9e-99 331.7 0.0 4e-99 331.3 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 GAK64767.1 - 6.1e-05 22.0 0.1 0.011 14.6 0.1 2.7 2 1 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.10 GAK64767.1 - 0.026 13.6 0.1 0.063 12.4 0.1 1.6 1 0 0 1 1 1 0 Nitronate monooxygenase LSM PF01423.17 GAK64768.1 - 5.3e-12 45.1 0.0 6.9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sel1 PF08238.7 GAK64769.1 - 8.7e-37 124.7 32.8 2.3e-06 28.0 0.4 7.8 7 0 0 7 7 7 7 Sel1 repeat DPBB_1 PF03330.13 GAK64770.1 - 1.1e-09 38.1 0.4 2.1e-09 37.2 0.3 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 GAK64770.1 - 0.027 14.1 0.4 0.042 13.5 0.1 1.4 1 1 0 1 1 1 0 Barwin family Glucodextran_B PF09136.5 GAK64770.1 - 0.075 13.1 1.5 0.18 11.9 0.1 2.0 1 1 1 2 2 2 0 Glucodextranase, domain B Toxin_1 PF00087.16 GAK64770.1 - 0.094 13.1 0.2 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Snake toxin AhpC-TSA PF00578.16 GAK64772.1 - 4.2e-24 84.5 0.0 6.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAK64772.1 - 4.9e-12 45.6 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 GAK64772.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme CKS PF01111.14 GAK64773.1 - 3.6e-30 103.5 0.2 5.1e-30 103.1 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Sec23_trunk PF04811.10 GAK64774.1 - 1.5e-74 250.4 0.0 2.5e-74 249.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAK64774.1 - 1.3e-22 79.1 0.3 3e-22 78.0 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 GAK64774.1 - 3.5e-16 58.4 8.9 6.7e-16 57.5 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 GAK64774.1 - 5e-16 59.0 0.0 1.4e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 GAK64774.1 - 6.6e-08 32.1 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 GAK64774.1 - 1.5e-05 24.7 1.3 3.1e-05 23.7 0.9 1.6 1 0 0 1 1 1 1 WW domain PWI PF01480.12 GAK64775.1 - 1.9e-08 34.2 0.1 4.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 GAK64775.1 - 2.1e-05 24.0 0.0 5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64775.1 - 0.09 12.7 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mpv17_PMP22 PF04117.7 GAK64776.1 - 5e-25 86.9 1.0 9.1e-25 86.0 0.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Thymidylate_kin PF02223.12 GAK64777.1 - 5.2e-43 146.5 0.0 8.6e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 GAK64777.1 - 0.0036 17.2 0.1 0.0036 17.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain PPK2 PF03976.9 GAK64777.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) TFIIF_alpha PF05793.7 GAK64778.1 - 3e-08 32.5 54.5 0.00039 18.9 0.0 3.7 3 1 1 4 4 4 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mre11_DNA_bind PF04152.9 GAK64778.1 - 0.48 10.2 5.2 7.9 6.2 0.5 2.8 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain Chitin_synth_2 PF03142.10 GAK64779.1 - 2.4e-241 801.7 0.3 3.2e-241 801.3 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 GAK64779.1 - 3.4e-150 501.3 0.0 5.2e-150 500.7 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 GAK64779.1 - 3e-17 62.1 0.1 1.2e-09 37.8 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 GAK64779.1 - 6e-17 61.9 0.9 1.7e-16 60.5 0.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DEK_C PF08766.6 GAK64779.1 - 1.4e-16 59.9 0.5 1.3e-15 56.8 0.2 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 GAK64779.1 - 3.7e-14 53.0 0.0 5.4e-12 46.0 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAK64779.1 - 0.0038 16.9 0.0 0.6 9.7 0.0 3.1 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAK64779.1 - 0.04 13.1 0.0 0.5 9.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Menin PF05053.8 GAK64780.1 - 9.7 4.2 15.7 11 3.9 10.9 1.1 1 0 0 1 1 1 0 Menin BRCA-2_OB1 PF09103.5 GAK64783.1 - 2e-31 108.1 0.0 3.4e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 GAK64783.1 - 8.7e-07 28.7 0.4 3.5e-06 26.7 0.6 1.7 2 0 0 2 2 2 1 BRCA2, helical BRCA2 PF00634.13 GAK64783.1 - 2.7e-06 26.5 0.2 5e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 BRCA2 repeat SIS PF01380.17 GAK64784.1 - 3e-59 198.2 0.1 6.8e-33 113.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 GAK64784.1 - 3.6e-28 98.3 0.0 7.6e-19 67.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAK64784.1 - 1.3e-18 67.2 0.0 3.1e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 GAK64784.1 - 9.6e-13 47.9 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 GAK64784.1 - 2.7e-07 29.5 0.0 4.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 GAK64784.1 - 0.01 15.5 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 0 SIS domain Plasmid_Txe PF06769.8 GAK64784.1 - 0.13 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Plasmid encoded toxin Txe 2-oxoacid_dh PF00198.18 GAK64785.1 - 3.9e-65 219.3 0.0 1e-64 217.9 0.0 1.7 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAK64785.1 - 5.2e-19 67.6 0.1 1.1e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 GAK64785.1 - 2.2e-17 62.3 0.4 9.9e-17 60.3 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain HlyD PF00529.15 GAK64785.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.7 1 0 0 1 1 1 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 GAK64785.1 - 0.058 13.0 0.0 1.6 8.4 0.0 2.8 1 1 1 2 2 2 0 Biotin-lipoyl like Helicase_C_2 PF13307.1 GAK64786.1 - 3.6e-54 183.1 0.0 8.7e-54 181.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 GAK64786.1 - 3.7e-44 150.1 0.0 5.6e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 GAK64786.1 - 0.062 13.1 0.0 4.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NUDIX-like PF09296.6 GAK64786.1 - 0.069 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain TPT PF03151.11 GAK64787.1 - 1.6e-23 83.0 12.1 1.6e-23 83.0 8.4 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family Sec61_beta PF03911.11 GAK64787.1 - 0.57 10.0 4.5 9.1 6.1 0.3 3.4 3 0 0 3 3 3 0 Sec61beta family PXA PF02194.10 GAK64788.1 - 9.6e-36 123.0 0.0 3.6e-35 121.1 0.0 2.1 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 GAK64788.1 - 1.3e-27 96.1 0.0 3.1e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 GAK64788.1 - 9.9e-15 54.3 0.0 3.4e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 PX domain RGS PF00615.14 GAK64788.1 - 1.4e-07 31.5 0.1 4.9e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF342 PF03961.8 GAK64788.1 - 1.5 7.1 2.7 0.58 8.5 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Mog1 PF04603.7 GAK64790.1 - 2.4e-30 105.3 0.1 3e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Sterol_MT_C PF08498.5 GAK64791.1 - 4.3e-29 100.2 0.9 7e-29 99.5 0.6 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 GAK64791.1 - 2.5e-20 72.6 0.0 3.9e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK64791.1 - 2.2e-18 66.5 0.0 4.1e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAK64791.1 - 1e-15 57.6 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 GAK64791.1 - 3.7e-15 56.0 0.0 5.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK64791.1 - 1.6e-13 51.2 0.0 7.8e-13 48.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK64791.1 - 2.2e-13 50.4 0.0 4.9e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK64791.1 - 1.7e-11 44.4 0.0 3.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK64791.1 - 2.5e-11 43.6 0.0 1.1e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK64791.1 - 3.4e-08 32.9 0.0 5.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 GAK64791.1 - 7.3e-06 25.1 0.0 1.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 GAK64791.1 - 2.9e-05 23.4 0.0 6.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 GAK64791.1 - 3.3e-05 23.5 0.1 5.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 GAK64791.1 - 7.1e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 GAK64791.1 - 0.00023 21.9 0.1 0.018 15.8 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain UPF0020 PF01170.13 GAK64791.1 - 0.00065 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.7 GAK64791.1 - 0.0043 16.4 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 GAK64791.1 - 0.0053 16.4 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAK64791.1 - 0.021 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.15 GAK64791.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 GAK64791.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 GAK64791.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DHFR_1 PF00186.14 GAK64792.1 - 4.2e-29 101.2 0.0 1.4e-28 99.5 0.0 1.7 1 1 0 1 1 1 1 Dihydrofolate reductase Cyclin_N PF00134.18 GAK64794.1 - 4e-13 49.0 0.1 1.1e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 GAK64794.1 - 3.5e-05 23.5 0.5 9.7e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 GAK64794.1 - 0.00025 20.9 0.3 0.38 10.6 0.1 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain DnaJ PF00226.26 GAK64795.1 - 6.9e-17 60.9 0.1 2.6e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain DUF2450 PF10475.4 GAK64795.1 - 0.026 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Cyclin_N PF00134.18 GAK64796.1 - 3.1e-08 33.2 2.2 4.8e-08 32.6 0.1 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAK64796.1 - 0.0086 15.9 1.2 0.36 10.7 0.3 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain SpoIIIAH PF12685.2 GAK64797.1 - 0.057 12.9 7.4 1.7 8.1 5.1 2.0 1 1 0 1 1 1 0 SpoIIIAH-like protein ATP-synt_ab PF00006.20 GAK64798.1 - 6e-61 205.6 0.0 1.1e-60 204.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 GAK64798.1 - 3.7e-24 84.7 4.3 9.7e-24 83.3 3.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 GAK64798.1 - 3.1e-23 82.4 0.1 5.1e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Arch_ATPase PF01637.13 GAK64798.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 GAK64798.1 - 0.02 13.9 0.2 0.035 13.2 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 GAK64798.1 - 0.022 14.1 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAK64798.1 - 0.13 11.9 0.3 4.1 7.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAK64798.1 - 0.15 11.7 0.1 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 GAK64798.1 - 0.15 11.1 0.1 0.28 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAK64798.1 - 0.18 11.9 0.0 0.6 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF463 PF04317.7 GAK64798.1 - 0.38 9.2 1.2 2.5 6.5 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 NB-ARC PF00931.17 GAK64798.1 - 0.65 8.7 1.5 1 8.1 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain ERCC4 PF02732.10 GAK64799.1 - 3.2e-27 95.0 0.0 9.3e-27 93.5 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain Pmp3 PF01679.12 GAK64800.1 - 5.7e-15 54.7 5.6 9e-15 54.1 3.9 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Glyco_transf_90 PF05686.7 GAK64801.1 - 9e-25 87.1 0.0 1.7e-24 86.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 XPG_I PF00867.13 GAK64802.1 - 3.6e-25 87.8 0.0 6.9e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAK64802.1 - 4.4e-23 81.4 0.0 9.7e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 GAK64802.1 - 0.00017 21.1 0.0 0.00059 19.4 0.0 1.9 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 GAK64802.1 - 0.005 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold LSM PF01423.17 GAK64803.1 - 1.8e-16 59.3 1.0 2.3e-16 59.0 0.7 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 GAK64803.1 - 0.029 14.1 0.1 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Redoxin PF08534.5 GAK64804.1 - 9.3e-10 38.2 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAK64804.1 - 7.8e-06 25.5 0.0 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family DUF899 PF05988.7 GAK64804.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Adap_comp_sub PF00928.16 GAK64805.1 - 1.2e-84 283.4 0.0 1.9e-84 282.8 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RNase_PH PF01138.16 GAK64805.1 - 6.1e-24 84.8 0.0 1.4e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Clat_adaptor_s PF01217.15 GAK64805.1 - 0.0015 18.2 0.7 0.0027 17.4 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Tim54 PF11711.3 GAK64806.1 - 3.4e-59 200.3 0.0 3.4e-59 200.3 0.0 2.9 1 1 1 2 2 2 1 Inner membrane protein import complex subunit Tim54 Adaptin_N PF01602.15 GAK64807.1 - 5.7e-104 348.3 0.0 1.4e-92 310.7 0.0 2.2 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 GAK64807.1 - 6.4e-09 35.9 5.6 0.0036 17.5 0.2 4.9 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 GAK64807.1 - 1.3e-07 31.5 0.0 0.00097 19.0 0.0 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 BLVR PF06375.6 GAK64807.1 - 3.8e-05 23.5 1.0 8.2e-05 22.4 0.7 1.6 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) HEAT PF02985.17 GAK64807.1 - 4.3e-05 23.2 3.3 6.4 7.1 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat TIP120 PF08623.5 GAK64807.1 - 0.014 15.0 4.4 0.14 11.7 0.1 3.2 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) ABC2_membrane PF01061.19 GAK64808.1 - 2.9e-30 105.0 19.1 2.9e-30 105.0 13.2 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 GAK64808.1 - 1.6e-26 93.2 0.0 2.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAK64808.1 - 3.3e-08 33.8 0.0 0.0028 17.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAK64808.1 - 4e-05 23.0 1.0 0.0084 15.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAK64808.1 - 8.9e-05 21.9 0.3 0.00029 20.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAK64808.1 - 0.00089 18.4 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAK64808.1 - 0.0011 18.9 0.2 0.0024 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAK64808.1 - 0.0053 16.8 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK64808.1 - 0.019 15.8 0.0 0.046 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAK64808.1 - 0.066 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAK64808.1 - 0.12 12.2 0.1 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAK64808.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 GAK64808.1 - 0.16 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 GAK64808.1 - 0.25 11.6 0.1 0.42 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_5 PF00266.14 GAK64809.1 - 1.5e-28 99.6 0.0 2.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V TPR_12 PF13424.1 GAK64810.1 - 1e-06 28.5 1.0 3.3e-06 26.9 0.7 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAK64810.1 - 0.14 12.8 2.9 0.3 11.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3235 PF11574.3 GAK64810.1 - 9.1 6.6 7.8 1.3 9.2 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) UAA PF08449.6 GAK64811.1 - 1.8e-69 233.9 3.2 1e-68 231.4 2.2 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAK64811.1 - 5.6e-10 39.3 19.7 6.6e-09 35.8 2.2 4.1 4 0 0 4 4 4 2 EamA-like transporter family TPT PF03151.11 GAK64811.1 - 1e-09 38.2 15.5 1.2e-08 34.7 3.8 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 GAK64811.1 - 2.4e-05 24.5 1.3 2.4e-05 24.5 0.9 3.5 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 GAK64811.1 - 0.0023 17.0 4.8 0.064 12.3 0.1 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter UPF0546 PF10639.4 GAK64811.1 - 0.054 13.3 2.8 2.7 7.8 0.3 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 OppC_N PF12911.2 GAK64811.1 - 0.097 12.0 1.7 0.16 11.3 0.3 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C PhyH PF05721.8 GAK64812.1 - 3.4e-05 23.9 0.0 6.5e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Lysine_decarbox PF03641.9 GAK64813.1 - 4.5e-32 110.6 0.1 8.8e-32 109.7 0.1 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase ABC_tran PF00005.22 GAK64813.1 - 1.1e-14 54.9 0.0 2.5e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAK64813.1 - 8.1e-10 39.1 0.2 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAK64813.1 - 2.7e-05 23.4 0.0 0.048 12.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAK64813.1 - 0.00046 19.6 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 GAK64813.1 - 0.0028 17.0 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAK64813.1 - 0.0048 16.9 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 GAK64813.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 GAK64813.1 - 0.024 13.8 0.0 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAK64813.1 - 0.041 14.6 0.4 0.097 13.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAK64813.1 - 0.049 12.8 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAK64813.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 GAK64813.1 - 0.071 12.5 0.1 1.2 8.6 0.0 2.5 1 1 1 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 GAK64813.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 GAK64813.1 - 0.1 11.8 0.1 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF4255 PF14065.1 GAK64813.1 - 0.13 11.7 0.1 0.27 10.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4255) Miro PF08477.8 GAK64813.1 - 0.15 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 GAK64813.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain L51_S25_CI-B8 PF05047.11 GAK64815.1 - 0.0003 20.4 0.0 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SH3_1 PF00018.23 GAK64816.1 - 1.3e-12 46.8 0.1 2.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAK64816.1 - 3.9e-10 39.1 0.0 6.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAK64816.1 - 1.5e-08 34.0 0.0 2.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kinesin PF00225.18 GAK64817.1 - 7.2e-100 333.9 0.4 2.4e-54 184.2 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain Filament PF00038.16 GAK64817.1 - 6.9 6.0 131.7 0.027 13.9 3.2 9.3 5 2 4 9 9 9 0 Intermediate filament protein TLV_coat PF00429.14 GAK64818.1 - 0.012 14.1 0.2 0.013 13.9 0.2 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) BSP_II PF05432.6 GAK64818.1 - 0.037 13.3 4.5 0.039 13.2 3.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.6 GAK64818.1 - 0.11 10.3 1.2 0.11 10.3 0.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med8 PF10232.4 GAK64818.1 - 0.12 11.8 1.9 0.13 11.7 1.3 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 AF1Q PF15017.1 GAK64818.1 - 0.15 11.9 3.1 2 8.3 2.4 2.0 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Nucleoplasmin PF03066.10 GAK64818.1 - 0.2 11.1 4.9 0.29 10.6 3.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 GAK64818.1 - 0.32 11.3 2.5 0.55 10.5 1.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BORG_CEP PF14957.1 GAK64818.1 - 0.67 10.8 3.2 0.45 11.4 1.1 1.4 1 1 0 1 1 1 0 Cdc42 effector RR_TM4-6 PF06459.7 GAK64818.1 - 0.68 9.7 4.5 0.93 9.3 3.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Myc_N PF01056.13 GAK64818.1 - 1.9 7.5 8.0 2.1 7.4 5.6 1.2 1 1 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 GAK64818.1 - 6.3 7.2 16.2 1.4 9.4 8.7 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein ECH PF00378.15 GAK64819.1 - 1.2e-39 135.9 0.0 1.6e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CBFD_NFYB_HMF PF00808.18 GAK64820.1 - 5.9e-19 67.9 0.2 5.9e-19 67.9 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAK64820.1 - 0.0068 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3753 PF12575.3 GAK64820.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DAHP_synth_1 PF00793.15 GAK64821.1 - 7e-93 310.2 0.0 8.5e-93 309.9 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family SRX PF09201.5 GAK64821.1 - 0.05 13.2 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 SRX zf-RING_2 PF13639.1 GAK64822.1 - 3.7e-13 49.0 6.2 6e-13 48.4 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAK64822.1 - 9.5e-09 34.8 5.8 1.5e-08 34.1 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK64822.1 - 2.8e-08 33.6 5.6 4.3e-08 33.0 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAK64822.1 - 3.2e-07 30.3 3.9 6e-07 29.4 2.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAK64822.1 - 1.3e-06 27.9 7.1 2.1e-06 27.3 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAK64822.1 - 5.2e-05 22.8 6.9 8.3e-05 22.1 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAK64822.1 - 0.00015 21.4 3.1 0.00032 20.3 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 GAK64822.1 - 0.37 10.4 3.8 0.66 9.6 2.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 GAK64822.1 - 0.59 10.0 3.2 1.3 8.9 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 GAK64822.1 - 8.3 6.3 5.4 15 5.5 3.8 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Peroxin-13_N PF04088.8 GAK64823.1 - 9.4e-54 181.6 0.1 1.8e-53 180.7 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 GAK64823.1 - 6.8e-13 47.9 0.1 2.5e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 GAK64823.1 - 1.3e-12 46.8 0.0 2.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAK64823.1 - 2.3e-11 43.0 0.0 3.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.9 GAK64823.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region WD40 PF00400.27 GAK64824.1 - 1.6e-71 233.8 20.4 1.2e-12 47.2 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAK64824.1 - 1e-13 50.3 10.6 5e-05 21.6 0.0 5.7 1 1 4 6 6 6 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAK64824.1 - 0.00033 19.5 1.6 0.89 8.2 0.1 3.8 1 1 0 3 3 3 3 Nup133 N terminal like LisH PF08513.6 GAK64824.1 - 0.0054 16.4 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 LisH IF-2B PF01008.12 GAK64825.1 - 2.6e-57 193.9 0.0 3.1e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DEAD PF00270.24 GAK64826.1 - 5.5e-47 159.3 0.0 3.8e-45 153.3 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK64826.1 - 3.5e-25 87.6 0.0 9.9e-25 86.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 GAK64826.1 - 0.0068 14.8 0.5 1.6 7.0 0.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF1253) Aminotran_3 PF00202.16 GAK64827.1 - 2.9e-109 365.0 0.0 4.3e-109 364.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAK64827.1 - 0.0014 17.6 0.0 0.0031 16.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAK64827.1 - 0.013 14.6 0.0 0.068 12.2 0.0 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase DUF2007 PF09413.5 GAK64827.1 - 0.054 13.3 0.1 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) DUF3128 PF11326.3 GAK64828.1 - 5.8e-24 84.0 0.8 5.8e-24 84.0 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) zf-H2C2_2 PF13465.1 GAK64829.1 - 3.2e-24 83.9 19.2 4.7e-07 29.7 0.1 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 GAK64829.1 - 3.6e-19 67.8 28.0 5.2e-06 26.4 1.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK64829.1 - 8.6e-11 41.3 24.8 0.013 15.7 1.1 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger Daxx PF03344.10 GAK64829.1 - 0.00013 20.6 10.7 0.00013 20.6 7.4 2.1 2 0 0 2 2 2 1 Daxx Family zf-C2H2_jaz PF12171.3 GAK64829.1 - 0.0014 18.6 6.9 0.37 11.0 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.5 GAK64829.1 - 0.003 18.0 11.8 0.003 18.0 8.2 2.9 3 0 0 3 3 2 1 Protein of unknown function (FYDLN_acid) zf-C2H2_6 PF13912.1 GAK64829.1 - 0.0095 15.8 14.8 0.036 13.9 0.7 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger Nop14 PF04147.7 GAK64829.1 - 0.019 12.9 18.3 0.031 12.1 12.7 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 GAK64829.1 - 0.022 14.0 11.8 0.041 13.1 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 GAK64829.1 - 0.16 10.7 27.4 0.32 9.6 19.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 GAK64829.1 - 0.19 10.9 18.9 0.36 10.0 13.1 1.4 1 0 0 1 1 1 0 SDA1 zf-TRAF PF02176.13 GAK64829.1 - 1 9.8 11.1 0.057 13.8 0.7 2.9 2 1 1 3 3 3 0 TRAF-type zinc finger zf-met PF12874.2 GAK64829.1 - 1.1 9.5 15.6 0.54 10.5 0.2 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type CDC45 PF02724.9 GAK64829.1 - 7.6 4.4 15.4 12 3.7 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_2b PF00587.20 GAK64832.1 - 1.2e-67 226.7 0.1 1.9e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAK64832.1 - 6.9e-21 73.9 0.1 2.6e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain DUF1465 PF07323.7 GAK64833.1 - 0.11 12.0 0.5 0.21 11.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) zf-H2C2_2 PF13465.1 GAK64834.1 - 1.9e-15 56.2 22.4 6.9e-07 29.2 0.1 5.1 4 1 1 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 GAK64834.1 - 6.8e-15 54.4 23.2 7.4e-05 22.8 1.1 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK64834.1 - 1e-05 25.4 24.6 0.0064 16.7 0.5 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger IGPD PF00475.13 GAK64834.1 - 0.053 13.3 0.6 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase IBR PF01485.16 GAK64834.1 - 1.4 8.8 9.2 0.56 10.1 1.3 2.5 1 1 1 2 2 2 0 IBR domain zf-TRAF PF02176.13 GAK64834.1 - 6.7 7.1 12.9 0.37 11.2 1.4 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger NUDIX PF00293.23 GAK64835.1 - 6.6e-18 64.6 0.1 3.1e-17 62.4 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain Sel1 PF08238.7 GAK64836.1 - 1.4e-08 35.0 19.4 4.9e-07 30.1 0.2 5.2 5 0 0 5 5 5 3 Sel1 repeat TPR_2 PF07719.12 GAK64836.1 - 0.0005 19.7 0.7 0.026 14.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAK64836.1 - 0.039 13.5 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAK64836.1 - 0.27 11.7 5.0 8.5 7.0 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAK64836.1 - 0.69 10.7 14.2 8.4 7.3 0.0 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat ATP-synt_10 PF05176.9 GAK64837.1 - 3.1e-58 197.0 0.0 3.8e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein GFO_IDH_MocA PF01408.17 GAK64839.1 - 3.4e-25 88.8 0.7 6.5e-25 87.9 0.5 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 GAK64839.1 - 0.00011 22.6 1.1 0.00018 21.8 0.8 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 GAK64839.1 - 0.00091 19.5 0.2 0.002 18.3 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Rossmann-like PF10727.4 GAK64839.1 - 0.0046 16.6 0.5 0.0077 15.9 0.4 1.4 1 0 0 1 1 1 1 Rossmann-like domain F420_oxidored PF03807.12 GAK64839.1 - 0.079 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Redoxin PF08534.5 GAK64840.1 - 2.6e-30 104.8 0.1 3.1e-30 104.6 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAK64840.1 - 4.3e-14 52.2 0.0 7.6e-14 51.4 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family RRM_1 PF00076.17 GAK64841.1 - 3.7e-07 29.6 0.0 4.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64841.1 - 8.4e-07 28.8 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64841.1 - 1.5e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAK64841.1 - 0.01 15.6 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif CC2D2AN-C2 PF15625.1 GAK64841.1 - 0.064 12.7 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Limkain-b1 PF11608.3 GAK64841.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 Fip1 PF05182.8 GAK64842.1 - 2.7e-20 71.3 3.4 2.7e-20 71.3 0.9 2.0 2 0 0 2 2 2 1 Fip1 motif PAS_9 PF13426.1 GAK64843.1 - 5.7e-26 90.9 0.0 6.1e-15 55.4 0.0 2.9 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 GAK64843.1 - 5.6e-16 58.3 0.0 3.7e-10 39.5 0.0 4.2 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.6 GAK64843.1 - 1.8e-14 53.6 0.0 4.9e-07 29.7 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.5 GAK64843.1 - 6.6e-08 32.5 0.0 0.00015 21.7 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 GAK64843.1 - 3.5e-06 26.6 0.0 0.0067 16.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 GAK64843.1 - 0.0011 18.9 0.0 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 PAS domain Med3 PF11593.3 GAK64844.1 - 5 6.2 5.9 5.8 6.0 3.7 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal TilS PF09179.6 GAK64845.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 TilS substrate binding domain SMC_N PF02463.14 GAK64846.1 - 2.6e-74 249.1 1.7 3.8e-73 245.3 1.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAK64846.1 - 2.8e-25 88.5 0.0 1.1e-24 86.6 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAK64846.1 - 1.1e-14 55.1 2.1 6.9e-07 29.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 GAK64846.1 - 7.6e-12 45.9 0.3 7.6e-12 45.9 0.2 6.5 4 2 1 5 5 5 1 AAA domain Reo_sigmaC PF04582.7 GAK64846.1 - 0.00044 19.5 27.1 0.022 13.9 0.1 4.5 2 2 1 4 4 4 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 GAK64846.1 - 0.00049 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF812 PF05667.6 GAK64846.1 - 0.0015 17.1 23.5 0.0015 17.1 16.3 4.8 4 1 1 5 5 5 1 Protein of unknown function (DUF812) DivIVA PF05103.8 GAK64846.1 - 0.0031 17.5 5.1 0.0031 17.5 3.5 8.5 4 3 6 10 10 10 2 DivIVA protein Pkinase PF00069.20 GAK64848.1 - 8.4e-61 205.3 0.0 3.6e-59 200.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64848.1 - 6e-29 100.9 0.0 5.8e-28 97.6 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK64848.1 - 3.8e-05 22.8 0.0 6.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Exo_endo_phos PF03372.18 GAK64849.1 - 1.2e-22 81.1 0.0 2e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 GAK64849.1 - 2.5e-13 49.3 5.3 4.6e-07 29.3 0.7 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK64849.1 - 9.2e-09 34.9 1.9 0.00022 20.9 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 GAK64849.1 - 4.9e-05 22.8 5.1 1.3 9.3 0.2 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 GAK64849.1 - 0.0028 17.5 5.8 4.3 7.9 0.2 4.3 4 0 0 4 4 4 2 Leucine rich repeat HSP90 PF00183.13 GAK64850.1 - 1.2e-246 819.2 27.7 1.5e-246 818.9 19.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 GAK64850.1 - 3.4e-12 46.0 0.0 7.1e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAK64850.1 - 1.8e-11 43.8 0.3 1.8e-11 43.8 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cellulase PF00150.13 GAK64851.1 - 7.7e-05 22.0 0.1 0.00012 21.4 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.8 GAK64852.1 - 2.3e-36 125.3 0.1 2.8e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK64852.1 - 1.2e-09 38.0 0.1 1.6e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK64852.1 - 4.9e-08 32.4 0.1 2.4e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAK64852.1 - 2.6e-06 27.4 3.8 2.7e-06 27.4 1.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK64852.1 - 0.0024 17.4 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAK64852.1 - 0.0043 16.3 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAK64852.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 GAK64852.1 - 0.0087 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 GAK64852.1 - 0.015 13.7 0.1 0.029 12.8 0.1 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.15 GAK64852.1 - 0.1 12.8 0.3 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain DUF2974 PF11187.3 GAK64852.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) adh_short PF00106.20 GAK64854.1 - 5.8e-23 81.6 0.2 7.9e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK64854.1 - 4.9e-10 39.3 0.1 8.8e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK64854.1 - 1e-06 28.7 0.0 1.5e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAK64854.1 - 0.00077 19.5 0.1 0.0037 17.2 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAK64854.1 - 0.033 12.8 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Erf4 PF10256.4 GAK64855.1 - 9.4e-10 38.3 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.1 GAK64855.1 - 7.8e-05 22.7 0.0 0.00019 21.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Esterase_phd PF10503.4 GAK64856.1 - 0.0001 21.6 0.1 0.00017 20.8 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.6 GAK64856.1 - 0.0026 17.4 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 GAK64856.1 - 0.0079 16.0 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK64856.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK64856.1 - 0.037 13.2 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pyridox_oxidase PF01243.15 GAK64857.1 - 0.0034 17.3 0.1 0.011 15.7 0.0 1.9 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Zn_clus PF00172.13 GAK64858.1 - 0.0012 18.7 7.3 0.0026 17.6 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 GAK64859.1 - 0.046 13.1 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 RTA1 like protein FMN_red PF03358.10 GAK64861.1 - 3.3e-24 85.1 0.0 5.8e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAK64861.1 - 0.0052 16.3 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold adh_short PF00106.20 GAK64862.1 - 1.3e-25 90.2 0.1 2.3e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK64862.1 - 2.2e-11 43.7 0.8 7.5e-11 42.0 0.6 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK64862.1 - 2.6e-06 27.3 0.4 3.8e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAK64862.1 - 0.0066 15.3 0.1 0.009 14.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAK64862.1 - 0.0076 16.2 0.4 0.021 14.8 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Abhydrolase_3 PF07859.8 GAK64863.1 - 2.8e-21 76.0 0.5 1.4e-19 70.5 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK64863.1 - 0.00065 19.4 0.1 0.0012 18.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1662 PF07878.6 GAK64863.1 - 0.18 11.5 1.5 1.7 8.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1662) NicO PF03824.11 GAK64864.1 - 1.8e-35 122.6 8.5 2.2e-31 109.2 0.0 3.5 3 1 0 3 3 3 2 High-affinity nickel-transport protein 4HBT_2 PF13279.1 GAK64865.1 - 1.4e-06 28.7 0.0 2.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HgmA PF04209.8 GAK64867.1 - 3.3e-175 582.5 0.2 3.8e-175 582.3 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Hemerythrin PF01814.18 GAK64868.1 - 6.3e-11 42.5 8.1 6.3e-11 42.5 5.6 1.7 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain CompInhib_SCIN PF11546.3 GAK64868.1 - 0.062 13.1 0.5 0.5 10.2 0.0 2.3 1 1 2 3 3 3 0 Staphylococcal complement inhibitor SCIN Tht1 PF04163.7 GAK64868.1 - 0.45 8.8 2.8 0.54 8.5 1.9 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Fungal_trans PF04082.13 GAK64869.1 - 3.8e-28 98.0 0.1 6.7e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK64869.1 - 1.4e-07 31.2 11.1 2.8e-07 30.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAK64870.1 - 1.2e-71 241.6 0.0 1.4e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 GAK64871.1 - 4.5e-46 157.0 0.0 6.4e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAK64871.1 - 3.1e-25 88.2 0.0 1.2e-24 86.3 0.0 2.0 2 1 1 3 3 3 1 Fumarylacetoacetase N-terminal PGAP1 PF07819.8 GAK64872.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein DIM PF08194.7 GAK64872.1 - 0.27 11.2 0.2 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 DIM protein Cyclin PF08613.6 GAK64873.1 - 2e-30 106.1 0.0 4.2e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAK64873.1 - 0.00019 20.9 0.1 0.00028 20.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Med24_N PF11277.3 GAK64873.1 - 0.13 9.7 1.0 0.17 9.3 0.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF59 PF01883.14 GAK64874.1 - 9.7e-09 35.0 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Nucleoporin_FG PF13634.1 GAK64876.1 - 1.5e-07 31.6 106.7 7.1e-06 26.2 34.0 3.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region AAA_13 PF13166.1 GAK64876.1 - 0.00021 19.9 2.7 0.036 12.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain Seryl_tRNA_N PF02403.17 GAK64876.1 - 0.0057 16.6 2.3 0.7 9.9 0.0 2.5 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 GAK64876.1 - 0.0097 15.4 2.9 1.6 8.2 0.4 3.0 2 1 1 3 3 3 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FUSC PF04632.7 GAK64876.1 - 0.01 14.3 5.2 0.018 13.5 3.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4618 PF15397.1 GAK64876.1 - 0.065 12.5 1.9 0.23 10.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF445 PF04286.7 GAK64876.1 - 0.12 11.8 1.3 0.17 11.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Mating_N PF12731.2 GAK64876.1 - 0.14 12.0 3.1 0.22 11.4 0.1 2.6 2 2 0 2 2 2 0 Mating-type protein beta 1 FlaC_arch PF05377.6 GAK64876.1 - 0.17 11.8 0.1 13 5.7 0.0 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Filament PF00038.16 GAK64876.1 - 0.3 10.4 4.7 2.3 7.6 0.4 2.2 2 0 0 2 2 2 0 Intermediate filament protein Ax_dynein_light PF10211.4 GAK64876.1 - 0.56 10.0 4.2 12 5.6 0.5 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain FlgN PF05130.7 GAK64876.1 - 1.2 9.3 6.4 3.3 7.9 0.7 3.1 2 1 1 3 3 3 0 FlgN protein DUF3722 PF12519.3 GAK64877.1 - 1.7e-92 309.3 0.6 3.5e-92 308.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 GAK64877.1 - 0.006 15.9 0.0 0.056 12.7 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic porin Ank_2 PF12796.2 GAK64878.1 - 1.1e-15 57.6 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAK64878.1 - 1.3e-12 47.8 0.5 4.8e-09 36.4 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 GAK64878.1 - 2.7e-12 45.8 0.1 2.9e-08 33.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 GAK64878.1 - 6.6e-11 42.0 0.4 7.3e-08 32.4 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK64878.1 - 1.2e-09 37.4 0.3 1.1e-05 25.2 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Methyltransf_18 PF12847.2 GAK64878.1 - 5.5e-05 23.7 0.0 0.0002 21.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK64878.1 - 0.04 14.4 0.0 0.25 11.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain SDA1 PF05285.7 GAK64878.1 - 0.19 11.0 0.1 0.44 9.7 0.0 1.5 2 0 0 2 2 2 0 SDA1 4HBT_3 PF13622.1 GAK64879.1 - 1.8e-35 122.8 0.6 2.2e-35 122.6 0.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily NTF2 PF02136.15 GAK64880.1 - 1.4e-26 93.2 0.6 4.7e-26 91.4 0.3 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 GAK64880.1 - 3.6e-05 23.3 0.0 7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64880.1 - 0.0002 21.2 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64880.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.1 GAK64880.1 - 0.016 14.2 0.4 0.024 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) RHD3 PF05879.7 GAK64881.1 - 1e-246 820.5 0.4 1.3e-246 820.1 0.3 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 GAK64881.1 - 3.8e-07 29.4 0.2 1.2e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 GAK64881.1 - 1.8e-05 24.6 0.0 4.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAK64881.1 - 2.7e-05 24.0 0.0 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 GAK64881.1 - 0.00011 22.7 0.0 0.00041 20.8 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 GAK64881.1 - 0.00029 20.8 0.0 0.001 19.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF2523 PF10734.4 GAK64881.1 - 0.029 14.5 0.1 0.069 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) Pyr_redox_2 PF07992.9 GAK64882.1 - 3.3e-18 66.2 0.0 3.7e-17 62.8 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK64882.1 - 2.2e-10 40.7 0.1 1.3e-09 38.2 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK64882.1 - 0.00041 20.4 0.0 0.0081 16.2 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK64882.1 - 0.18 10.6 2.1 0.43 9.4 0.1 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase HSP20 PF00011.16 GAK64883.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family MRP-S33 PF08293.6 GAK64884.1 - 5.1e-23 80.8 0.0 6.8e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Peptidase_C14 PF00656.17 GAK64885.1 - 3e-64 217.1 0.1 3.7e-64 216.7 0.1 1.0 1 0 0 1 1 1 1 Caspase domain MBOAT PF03062.14 GAK64886.1 - 1.3e-47 162.4 1.2 1.3e-47 162.4 0.8 2.3 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family FA_hydroxylase PF04116.8 GAK64887.1 - 1.4e-12 48.0 13.7 1.4e-12 48.0 9.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2013 PF09431.5 GAK64888.1 - 8.1e-51 171.4 0.2 1.3e-50 170.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Methyltransf_3 PF01596.12 GAK64889.1 - 1.1e-47 161.7 0.4 1.5e-47 161.2 0.3 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAK64889.1 - 5.8e-12 46.3 0.0 1.3e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK64889.1 - 1.5e-07 31.9 0.1 3.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK64889.1 - 8.1e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAK64889.1 - 0.0013 18.2 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 GAK64889.1 - 0.0037 16.8 0.1 0.0055 16.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAK64889.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.6 1 1 0 1 1 1 0 Conserved hypothetical protein 95 TBCC PF07986.7 GAK64890.1 - 1.2e-11 44.1 3.5 1.9e-11 43.3 2.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Chorismate_synt PF01264.16 GAK64891.1 - 4.9e-131 436.3 0.5 1.7e-64 217.5 0.1 2.0 2 0 0 2 2 2 2 Chorismate synthase EthD PF07110.6 GAK64892.1 - 5.5e-06 27.2 0.4 0.021 15.7 0.0 2.6 2 1 0 2 2 2 2 EthD domain DUF4286 PF14114.1 GAK64892.1 - 0.012 15.9 0.0 5.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Coatomer_WDAD PF04053.9 GAK64893.1 - 9.9e-156 518.9 0.0 2.2e-155 517.8 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 GAK64893.1 - 9.3e-50 164.8 11.5 2.1e-11 43.2 0.3 7.8 9 0 0 9 9 9 6 WD domain, G-beta repeat DUF4140 PF13600.1 GAK64893.1 - 0.042 14.3 0.4 0.11 12.9 0.3 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BBS2_Mid PF14783.1 GAK64893.1 - 0.053 13.3 0.0 12 5.7 0.0 3.7 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region TPR_2 PF07719.12 GAK64893.1 - 0.082 12.8 0.2 11 6.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MgtE_N PF03448.12 GAK64893.1 - 0.2 11.9 3.0 0.4 11.0 1.1 2.1 2 0 0 2 2 2 0 MgtE intracellular N domain TPR_4 PF07721.9 GAK64893.1 - 0.51 10.9 4.4 2.3 8.9 0.8 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAK64893.1 - 1 9.7 5.3 1.3 9.4 0.5 2.9 2 2 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 GAK64894.1 - 5.1e-12 45.6 0.6 1.1e-11 44.6 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAK64894.1 - 4.3e-08 33.1 0.8 1e-07 31.9 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Vps5 PF09325.5 GAK64895.1 - 1.5e-16 60.3 7.3 2.2e-16 59.8 5.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like DUF2422 PF10337.4 GAK64895.1 - 0.51 9.0 6.7 0.84 8.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) SWIB PF02201.13 GAK64896.1 - 9.1e-28 95.7 0.0 1.3e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 GAK64896.1 - 2.8e-06 26.9 0.1 1.7e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 DEK C terminal domain ORC6 PF05460.8 GAK64896.1 - 0.0098 15.0 4.2 0.011 14.8 2.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Bindin PF02084.10 GAK64896.1 - 0.11 12.5 3.5 0.15 12.0 2.4 1.1 1 0 0 1 1 1 0 Bindin CDC27 PF09507.5 GAK64896.1 - 6.4 5.8 14.3 10 5.2 9.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNase_T PF00929.19 GAK64897.1 - 1.9e-25 90.0 0.0 2.8e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease 2-Hacid_dh_C PF02826.14 GAK64898.1 - 2.4e-53 179.9 0.0 3.8e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAK64898.1 - 3.2e-14 52.5 0.0 4.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAK64898.1 - 1.2e-05 25.2 0.1 2.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 GAK64898.1 - 0.00069 19.7 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAK64898.1 - 0.0043 17.4 0.0 0.014 15.8 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Peptidase_M19 PF01244.16 GAK64898.1 - 0.034 13.0 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Pyr_redox PF00070.22 GAK64898.1 - 0.055 13.8 0.1 0.2 12.0 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.17 GAK64898.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.11 GAK64898.1 - 0.11 11.9 0.3 0.23 10.8 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pectate_lyase_3 PF12708.2 GAK64899.1 - 8.3e-84 281.2 5.5 1.9e-64 217.8 2.9 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAK64899.1 - 1.3e-07 30.9 1.0 0.015 14.7 0.3 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 GAK64899.1 - 3.5 7.3 12.5 0.99 9.1 5.5 2.5 2 1 0 2 2 2 0 Right handed beta helix region PP2C PF00481.16 GAK64900.1 - 3.5e-65 219.9 0.2 7.3e-52 176.2 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 GAK64900.1 - 0.031 13.9 0.2 0.32 10.6 0.1 2.4 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) HMG_box PF00505.14 GAK64901.1 - 5.1e-21 74.7 15.8 7.9e-11 42.0 3.0 3.0 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 GAK64901.1 - 2.2e-18 66.3 12.2 7.2e-09 35.8 0.8 2.6 2 0 0 2 2 2 2 HMG-box domain Methyltransf_16 PF10294.4 GAK64901.1 - 3.5e-17 62.4 0.1 5.6e-12 45.4 0.0 2.3 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 GAK64901.1 - 6e-05 23.5 0.0 0.00017 22.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK64901.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain YABBY PF04690.8 GAK64901.1 - 1.4 9.1 11.9 0.029 14.6 2.5 2.4 2 1 1 3 3 3 0 YABBY protein TATR PF03430.8 GAK64901.1 - 8.9 4.8 7.8 15 4.0 5.4 1.3 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF3275 PF11679.3 GAK64902.1 - 4.7 6.7 7.0 6.5 6.3 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) CRAL_TRIO PF00650.15 GAK64903.1 - 5.8e-36 123.3 0.1 9.1e-36 122.7 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAK64903.1 - 5.7e-12 45.5 1.0 1.5e-11 44.2 0.2 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CBF_beta PF02312.12 GAK64903.1 - 0.21 11.2 2.6 2.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Core binding factor beta subunit Acetyltransf_1 PF00583.19 GAK64904.1 - 1.1e-15 57.4 0.1 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAK64904.1 - 1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAK64904.1 - 2.8e-05 24.1 0.0 3.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAK64904.1 - 0.0004 20.2 0.0 0.00054 19.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAK64904.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAK64904.1 - 0.019 14.9 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNase_H PF00075.19 GAK64906.1 - 0.0027 18.0 0.0 0.012 15.9 0.0 2.0 2 0 0 2 2 2 1 RNase H Corona_nucleoca PF00937.13 GAK64907.1 - 1.9 7.3 16.1 0.65 8.8 4.8 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Prenyltransf PF01255.14 GAK64908.1 - 5.2e-75 251.4 0.0 6.6e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Peptidase_S26 PF10502.4 GAK64909.1 - 1.3e-06 28.0 0.0 0.00024 20.6 0.0 2.5 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 GAK64909.1 - 1.8e-05 24.2 0.0 0.00014 21.4 0.0 2.2 1 1 0 1 1 1 1 Peptidase S24-like RhoGEF PF00621.15 GAK64910.1 - 2.1e-24 86.3 0.0 4.3e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain PH PF00169.24 GAK64910.1 - 0.00059 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 PH domain DPBB_1 PF03330.13 GAK64912.1 - 0.0054 16.7 0.1 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Fer4_7 PF12838.2 GAK64912.1 - 0.027 14.8 0.1 0.074 13.4 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain CAP_GLY PF01302.20 GAK64914.1 - 2.5e-21 75.1 0.2 3.9e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 GAK64914.1 - 1.1e-13 50.4 9.4 1.7e-06 27.4 1.1 4.7 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK64914.1 - 1.7e-11 43.6 10.2 2.2e-07 30.5 0.6 4.1 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 GAK64914.1 - 7.8e-07 28.2 6.8 4.2 7.7 0.0 6.3 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 GAK64914.1 - 1.2e-05 24.7 8.2 8.9 7.0 0.0 6.5 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 GAK64914.1 - 0.00011 21.8 15.0 6.1 7.2 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.1 GAK64914.1 - 0.0033 16.9 0.1 0.18 11.3 0.0 2.6 1 1 1 2 2 2 2 Leucine-rich repeat HEAT_2 PF13646.1 GAK64915.1 - 0.023 14.9 0.4 0.3 11.4 0.1 2.2 1 1 1 2 2 2 0 HEAT repeats DUF3661 PF12400.3 GAK64917.1 - 6.4e-40 136.2 0.1 1.2e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein DUF4611 PF15387.1 GAK64917.1 - 4.6 7.4 6.8 1.3 9.2 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) GN3L_Grn1 PF08701.6 GAK64918.1 - 2.8e-24 84.8 16.3 2.8e-24 84.8 11.3 4.6 5 0 0 5 5 5 1 GNL3L/Grn1 putative GTPase CENP-B_dimeris PF09026.5 GAK64918.1 - 0.00058 20.0 2.8 0.00058 20.0 1.9 6.3 5 1 0 5 5 5 1 Centromere protein B dimerisation domain MMR_HSR1 PF01926.18 GAK64918.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Daxx PF03344.10 GAK64918.1 - 1.9 6.8 54.8 1.1 7.6 6.4 3.2 3 0 0 3 3 3 0 Daxx Family SGT1 PF07093.6 GAK64918.1 - 2 6.6 38.4 0.011 14.1 5.8 2.8 2 1 0 2 2 2 0 SGT1 protein RRN3 PF05327.6 GAK64919.1 - 1.2e-186 621.2 0.0 1.7e-186 620.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Thioredoxin PF00085.15 GAK64920.1 - 3e-24 84.6 0.3 3.7e-24 84.4 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAK64920.1 - 2.3e-09 37.4 0.2 9.4e-09 35.4 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAK64920.1 - 1.2e-08 34.8 0.1 4.4e-07 29.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 GAK64920.1 - 6.6e-06 26.0 0.1 8.7e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 GAK64920.1 - 4.7e-05 23.1 0.1 9.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 GAK64920.1 - 0.00012 21.7 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAK64920.1 - 0.00064 19.2 0.5 0.0073 15.8 0.2 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 GAK64920.1 - 0.0053 16.3 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin KaiB PF07689.7 GAK64920.1 - 0.021 14.3 0.1 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 KaiB domain DUF836 PF05768.9 GAK64920.1 - 0.021 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.6 GAK64920.1 - 0.037 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.1 GAK64920.1 - 0.051 13.0 0.1 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein PhaP_Bmeg PF09602.5 GAK64920.1 - 0.091 12.5 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Glutaredoxin PF00462.19 GAK64920.1 - 0.31 11.0 1.7 0.96 9.4 1.2 1.9 1 1 0 1 1 1 0 Glutaredoxin zf-CCHC PF00098.18 GAK64922.1 - 2.8e-28 96.4 38.9 1.1e-07 31.4 1.3 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 GAK64922.1 - 1.7e-07 30.8 26.6 0.037 13.6 0.3 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 GAK64922.1 - 9.6e-06 24.9 27.8 0.0069 15.8 0.6 4.9 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.1 GAK64922.1 - 0.0013 18.3 28.7 0.14 11.8 1.1 5.1 2 1 3 5 5 5 3 Zinc knuckle Adaptin_N PF01602.15 GAK64923.1 - 8.2e-122 407.1 11.7 1e-121 406.9 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 GAK64923.1 - 1.4e-39 134.5 0.0 4.3e-39 132.9 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 GAK64923.1 - 1.1e-15 57.9 0.0 2.7e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain 14-3-3 PF00244.15 GAK64924.1 - 6.8e-118 391.9 5.6 8.2e-118 391.6 3.9 1.1 1 0 0 1 1 1 1 14-3-3 protein Vma12 PF11712.3 GAK64924.1 - 0.041 13.6 2.9 5.2 6.7 0.6 2.5 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF837 PF05769.6 GAK64924.1 - 0.081 12.4 2.8 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Ras PF00071.17 GAK64925.1 - 3e-50 169.7 0.0 3.6e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK64925.1 - 4.2e-16 59.5 0.0 6.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK64925.1 - 2.1e-10 40.0 0.0 2.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAK64925.1 - 3.6e-05 23.0 0.0 4.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAK64925.1 - 0.0013 17.4 1.2 0.75 8.4 0.0 2.9 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 GAK64925.1 - 0.014 15.5 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 GAK64925.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 GAK64925.1 - 0.042 13.9 0.1 0.13 12.3 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAK64925.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 GAK64925.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain KaiC PF06745.8 GAK64925.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 KaiC SHS2_Rpb7-N PF03876.12 GAK64926.1 - 6.8e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF972 PF06156.8 GAK64927.1 - 4.5 7.6 8.1 0.26 11.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_60s PF00428.14 GAK64928.1 - 0.049 14.0 2.7 0.056 13.8 1.9 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein FUSC PF04632.7 GAK64930.1 - 1.2e-15 57.0 7.8 1.2e-15 57.0 5.4 3.3 4 0 0 4 4 4 1 Fusaric acid resistance protein family FUSC_2 PF13515.1 GAK64930.1 - 2.5e-14 53.3 7.6 2.5e-14 53.3 5.3 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 GAK64930.1 - 8.7e-09 34.5 1.9 8.7e-09 34.5 1.3 2.1 2 0 0 2 2 2 1 Aluminium activated malate transporter DUF2422 PF10337.4 GAK64930.1 - 6.7e-07 28.4 7.2 8.4e-06 24.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF939 PF06081.6 GAK64930.1 - 6e-06 26.1 2.9 6e-06 26.1 2.0 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF939) DUF2421 PF10334.4 GAK64930.1 - 1.1e-05 25.2 1.1 2.6e-05 23.9 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) PepSY_TM_3 PF13706.1 GAK64930.1 - 0.055 12.8 0.1 0.055 12.8 0.1 2.6 2 0 0 2 2 2 0 PepSY-associated TM helix TrmE_N PF10396.4 GAK64931.1 - 1.7e-30 105.2 0.1 4.7e-30 103.8 0.1 1.8 2 0 0 2 2 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 GAK64931.1 - 1.4e-20 73.4 0.4 4.2e-20 71.9 0.0 2.1 2 0 0 2 2 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 GAK64931.1 - 6.6e-19 67.9 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK64931.1 - 2.5e-05 23.6 0.0 3.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAK64931.1 - 0.00028 20.7 0.0 0.00062 19.6 0.0 1.5 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 GAK64931.1 - 0.00029 21.3 0.0 0.0007 20.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 GAK64931.1 - 0.00074 20.3 0.0 0.0017 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAK64931.1 - 0.00083 19.3 0.0 0.0077 16.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain cobW PF02492.14 GAK64931.1 - 0.0023 17.3 0.0 0.94 8.8 0.0 2.3 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 GAK64931.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Hydantoinase_A PF01968.13 GAK64931.1 - 0.016 14.3 0.2 0.49 9.4 0.0 2.3 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase AAA_22 PF13401.1 GAK64931.1 - 0.035 14.2 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAK64931.1 - 0.037 13.6 0.0 0.22 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain PTH2 PF01981.11 GAK64932.1 - 0.0011 18.6 0.4 0.0023 17.6 0.1 1.6 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 CotJB PF12652.2 GAK64932.1 - 0.044 13.8 0.5 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 CotJB protein Sybindin PF04099.7 GAK64933.1 - 3.8e-38 130.3 0.0 5e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 GAK64933.1 - 8.8e-08 32.0 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PCI PF01399.22 GAK64934.1 - 3.2e-11 43.4 0.0 7.3e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain Coatomer_E PF04733.9 GAK64936.1 - 9.3e-43 146.4 5.4 1.1e-42 146.2 3.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_11 PF13414.1 GAK64936.1 - 4e-05 23.1 5.5 0.00049 19.6 0.3 3.5 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 GAK64936.1 - 0.014 15.5 0.3 0.42 10.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAK64936.1 - 0.014 15.9 1.1 0.014 15.9 0.8 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 GAK64936.1 - 0.087 12.9 0.6 0.087 12.9 0.4 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAK64936.1 - 0.23 11.7 13.6 7.3 7.0 1.7 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 GAK64936.1 - 1.8 8.7 5.9 5.1 7.3 0.0 3.3 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Hist_deacetyl PF00850.14 GAK64937.1 - 4.3e-76 256.1 0.1 6.2e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ELYS PF13934.1 GAK64938.1 - 1.5e-27 96.8 0.2 2e-27 96.4 0.2 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF3237 PF11578.3 GAK64939.1 - 4.6e-30 103.9 0.0 5.1e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) CBS PF00571.23 GAK64941.1 - 1.4e-19 69.5 6.5 1.6e-05 24.6 0.2 5.1 5 0 0 5 5 5 4 CBS domain F-box-like PF12937.2 GAK64942.1 - 1.1e-11 44.2 3.6 1.1e-11 44.2 2.5 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 GAK64942.1 - 6.6e-08 32.0 1.2 0.089 12.4 0.0 5.6 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAK64942.1 - 9.2e-06 25.0 12.8 11 6.4 0.0 8.0 7 3 1 8 8 8 2 Leucine Rich Repeat F-box PF00646.28 GAK64942.1 - 1.5e-05 24.5 6.2 4.1e-05 23.0 0.8 3.5 4 0 0 4 4 4 1 F-box domain LRR_8 PF13855.1 GAK64942.1 - 0.00015 21.4 11.9 0.96 9.2 0.0 5.7 3 2 3 6 6 6 4 Leucine rich repeat Ste50p-SAM PF09235.5 GAK64942.1 - 0.13 12.3 1.5 32 4.6 0.0 3.6 3 0 0 3 3 3 0 Ste50p, sterile alpha motif Myb_DNA-binding PF00249.26 GAK64943.1 - 1.7e-09 37.6 1.4 1.9e-05 24.6 0.0 3.6 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAK64943.1 - 1e-05 25.5 1.2 0.022 14.8 0.0 4.0 2 2 1 3 3 3 2 Myb-like DNA-binding domain YrpD PF15493.1 GAK64943.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, YrpD DUF4611 PF15387.1 GAK64944.1 - 0.017 15.2 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3651 PF12371.3 GAK64944.1 - 0.04 13.9 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3651) P21-Arc PF04062.9 GAK64945.1 - 5.7e-75 250.8 0.0 6.4e-75 250.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Methyltransf_16 PF10294.4 GAK64946.1 - 1.7e-14 53.6 0.0 2.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAK64946.1 - 6.8e-07 29.8 0.1 1.3e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 GAK64946.1 - 0.00027 20.1 0.1 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAK64946.1 - 0.006 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAK64946.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 GAK64946.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NIF PF03031.13 GAK64947.1 - 2.6e-43 147.4 0.0 3.8e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MSP1_C PF07462.6 GAK64947.1 - 2.5 6.3 4.8 3.7 5.8 3.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Asp_protease PF09668.5 GAK64948.1 - 1.4e-60 202.2 0.0 2.1e-60 201.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 GAK64948.1 - 7e-12 45.6 0.0 2.4e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 GAK64948.1 - 5.7e-10 38.4 0.0 1.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 GAK64948.1 - 5.3e-07 29.3 0.0 1.9e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA_4 PF14555.1 GAK64948.1 - 0.00011 21.6 0.3 0.00027 20.4 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.6 GAK64948.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 GAK64948.1 - 0.00013 21.6 0.3 0.00064 19.4 0.0 2.4 3 0 0 3 3 3 1 UBA/TS-N domain RVP PF00077.15 GAK64948.1 - 0.00016 21.4 0.0 0.00044 20.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 GAK64948.1 - 0.00017 21.1 0.1 0.00037 20.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.6 GAK64948.1 - 0.00026 20.3 4.2 0.00076 18.8 2.9 1.8 1 0 0 1 1 1 1 XPC-binding domain Mob1_phocein PF03637.12 GAK64949.1 - 3.3e-56 189.6 0.2 4.1e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family ABC_tran PF00005.22 GAK64950.1 - 7.4e-45 152.6 0.0 3.7e-22 79.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 GAK64950.1 - 1.4e-20 72.8 2.9 1.4e-20 72.8 2.0 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 GAK64950.1 - 4.1e-19 69.6 0.7 0.00099 19.1 0.0 4.4 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 GAK64950.1 - 5.8e-09 35.3 0.6 0.0012 18.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 GAK64950.1 - 1.1e-07 31.3 2.3 0.47 9.6 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 GAK64950.1 - 1.1e-07 32.3 0.0 0.013 15.9 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 GAK64950.1 - 4.9e-07 30.2 18.0 0.00078 19.8 1.1 4.3 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 GAK64950.1 - 1.4e-06 29.1 0.1 0.067 14.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 GAK64950.1 - 3.9e-06 26.1 0.0 0.0018 17.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAK64950.1 - 4.8e-06 26.5 2.5 0.1 12.3 0.0 4.1 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 GAK64950.1 - 6.7e-06 26.2 1.0 0.28 11.3 0.1 4.0 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAK64950.1 - 1.1e-05 25.2 1.1 0.0064 16.4 0.2 3.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_25 PF13481.1 GAK64950.1 - 1.3e-05 24.6 0.1 0.66 9.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 GAK64950.1 - 4.9e-05 23.0 0.8 0.34 10.5 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 GAK64950.1 - 6.4e-05 22.1 9.1 0.28 10.2 0.0 4.7 4 1 1 5 5 5 2 AAA ATPase domain AAA_18 PF13238.1 GAK64950.1 - 0.00028 21.2 1.3 0.72 10.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 GAK64950.1 - 0.00028 20.9 0.5 0.17 11.8 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAK64950.1 - 0.00045 19.7 0.1 0.4 10.1 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 GAK64950.1 - 0.00068 19.1 0.4 0.44 9.9 0.1 3.0 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 GAK64950.1 - 0.00087 19.4 1.5 3.3 7.9 0.0 4.1 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 GAK64950.1 - 0.001 18.3 0.1 0.069 12.4 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_28 PF13521.1 GAK64950.1 - 0.0012 18.8 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 GAK64950.1 - 0.002 17.8 5.1 0.29 10.8 0.1 3.5 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 GAK64950.1 - 0.003 17.1 0.0 0.49 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK64950.1 - 0.003 17.2 0.2 1.6 8.5 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 GAK64950.1 - 0.0037 17.1 0.0 0.82 9.6 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 GAK64950.1 - 0.0097 15.5 1.2 4.6 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 GAK64950.1 - 0.01 15.7 0.1 16 5.3 0.0 4.0 4 0 0 4 4 4 0 AAA domain T2SE PF00437.15 GAK64950.1 - 0.013 14.4 0.2 3.5 6.4 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_5 PF07728.9 GAK64950.1 - 0.016 14.9 0.5 0.81 9.4 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAK64950.1 - 0.018 14.9 0.2 8.3 6.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.7 GAK64950.1 - 0.021 14.1 0.9 5.6 6.1 0.1 3.1 2 1 1 3 3 3 0 Poxvirus A32 protein cobW PF02492.14 GAK64950.1 - 0.023 14.1 0.1 4.1 6.8 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 GAK64950.1 - 0.028 13.2 0.0 4.8 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DAP3 PF10236.4 GAK64950.1 - 0.031 13.2 1.3 3.9 6.3 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.17 GAK64950.1 - 0.032 14.4 0.5 3.3 7.9 0.0 3.0 3 0 0 3 3 2 0 RNA helicase SRP54 PF00448.17 GAK64950.1 - 0.048 13.1 2.2 1.5 8.2 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 GAK64950.1 - 0.074 12.5 0.8 11 5.5 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 GAK64950.1 - 0.1 12.3 8.8 0.83 9.4 0.0 4.2 3 1 1 4 4 4 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 GAK64950.1 - 1.7 8.3 5.7 3.5 7.3 0.1 3.4 5 0 0 5 5 3 0 NTPase DivIC PF04977.10 GAK64950.1 - 4.8 6.7 16.1 1.2 8.6 1.2 3.1 3 0 0 3 3 3 0 Septum formation initiator Ribosomal_L23eN PF03939.8 GAK64950.1 - 7.9 6.5 8.8 27 4.8 6.1 1.9 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain MRP-L27 PF09809.4 GAK64951.1 - 6.4e-05 22.5 1.6 0.0033 17.0 1.1 2.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 Sugarporin_N PF11471.3 GAK64952.1 - 0.052 13.2 2.2 0.2 11.3 1.5 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension SPRY PF00622.23 GAK64953.1 - 3e-06 27.3 0.0 1.3e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 SPRY domain DEAD PF00270.24 GAK64955.1 - 4.3e-42 143.4 0.0 7.1e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK64955.1 - 2.7e-23 81.6 0.0 5.8e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK64955.1 - 0.0025 17.6 0.0 0.0096 15.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Erv26 PF04148.8 GAK64956.1 - 5.1e-11 42.3 4.5 5.4e-10 39.0 3.1 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Acyl-CoA_dh_N PF02771.11 GAK64957.1 - 1.1e-26 93.6 0.0 2.3e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 GAK64957.1 - 4.9e-25 88.3 0.0 7.4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAK64957.1 - 2.9e-19 68.3 3.6 5.2e-19 67.4 0.0 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAK64957.1 - 1.2e-09 38.5 0.6 2.4e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Mod_r PF07200.8 GAK64959.1 - 2.8e-19 69.5 7.4 1.3e-17 64.1 1.4 2.3 3 0 0 3 3 3 2 Modifier of rudimentary (Mod(r)) protein NUDIX PF00293.23 GAK64960.1 - 4.6e-14 52.1 0.0 7.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF2435 PF10363.4 GAK64961.1 - 6.1e-28 96.5 0.0 2.6e-27 94.5 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 GAK64961.1 - 0.0046 16.4 3.6 0.0054 16.2 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) HEAT PF02985.17 GAK64961.1 - 0.37 11.0 3.4 21 5.5 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat Iso_dh PF00180.15 GAK64962.1 - 7e-80 268.5 0.0 8.7e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase OppC_N PF12911.2 GAK64962.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Iso_dh PF00180.15 GAK64963.1 - 1.7e-100 336.3 0.0 2e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COesterase PF00135.23 GAK64964.1 - 4.2e-72 243.5 0.0 6.1e-71 239.7 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DnaJ PF00226.26 GAK64964.1 - 8.4e-14 51.0 0.0 1.7e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 GAK64964.1 - 3.8e-12 45.5 0.7 7.1e-12 44.6 0.5 1.5 1 0 0 1 1 1 1 CSL zinc finger Abhydrolase_3 PF07859.8 GAK64964.1 - 1.6e-05 24.6 0.0 0.00069 19.2 0.0 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold ZZ PF00569.12 GAK64964.1 - 0.06 12.8 0.2 0.49 9.9 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type RRM_1 PF00076.17 GAK64965.1 - 2.7e-14 52.5 0.0 3.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK64965.1 - 3.4e-12 46.1 0.0 5.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK64965.1 - 2.8e-09 36.6 0.0 4.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18e PF00828.14 GAK64966.1 - 9.7e-25 87.4 0.0 2.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Hyphal_reg_CWP PF11765.3 GAK64966.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal Isy1 PF06246.7 GAK64967.1 - 6.5e-79 264.9 0.6 1.2e-78 264.0 0.4 1.4 1 1 0 1 1 1 1 Isy1-like splicing family VID27 PF08553.5 GAK64968.1 - 0 1058.6 1.0 0 1058.3 0.7 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein eIF-3_zeta PF05091.7 GAK64969.1 - 9.1e-187 621.7 0.0 1.1e-186 621.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.20 GAK64970.1 - 3e-41 141.2 0.0 1.6e-23 83.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK64970.1 - 2e-12 46.7 0.0 1.4e-09 37.4 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 GAK64970.1 - 0.0021 17.8 2.3 0.032 13.9 0.0 3.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 GAK64970.1 - 0.074 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAP18 PF06487.7 GAK64971.1 - 6.6e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Rad60-SLD PF11976.3 GAK64971.1 - 0.12 12.0 0.4 16 5.2 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L7Ae PF01248.21 GAK64972.1 - 1e-28 98.6 0.8 1.3e-28 98.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Clathrin_lg_ch PF01086.12 GAK64973.1 - 1.2e-33 116.9 14.5 2e-31 109.6 10.1 2.2 1 1 0 1 1 1 1 Clathrin light chain Ribosomal_S17 PF00366.15 GAK64973.1 - 4e-29 100.4 2.7 7.5e-29 99.5 1.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Metallophos PF00149.23 GAK64974.1 - 2.2e-42 144.7 0.7 3.1e-42 144.2 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ACC_central PF08326.7 GAK64974.1 - 0.15 10.1 0.1 0.25 9.4 0.1 1.2 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region FAD-oxidase_C PF02913.14 GAK64975.1 - 1.4e-58 198.1 0.0 2e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAK64975.1 - 3.6e-35 120.4 1.1 6.2e-35 119.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Cid2 PF09774.4 GAK64975.1 - 1.1e-33 116.5 0.0 1.8e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Ilar_coat PF01787.11 GAK64975.1 - 0.02 14.4 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 Ilarvirus coat protein EpuA PF11772.3 GAK64975.1 - 0.11 11.9 0.3 0.33 10.4 0.2 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta SMP_2 PF10144.4 GAK64975.1 - 0.16 11.0 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin Clathrin PF00637.15 GAK64976.1 - 4.8e-24 84.5 0.2 3.2e-23 81.9 0.0 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 GAK64976.1 - 0.00072 19.3 0.9 0.084 12.7 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 GAK64976.1 - 0.21 11.4 0.4 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Ring finger domain GRIM-19 PF06212.7 GAK64977.1 - 1.1e-36 125.4 0.0 1.5e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein Coiled-coil_56 PF09813.4 GAK64977.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Nop14 PF04147.7 GAK64978.1 - 2.6e-255 849.3 18.7 4.8e-255 848.5 12.9 1.3 1 1 0 1 1 1 1 Nop14-like family TIP41 PF04176.8 GAK64979.1 - 3.8e-44 150.1 0.0 1.3e-39 135.2 0.0 2.8 2 1 0 2 2 2 2 TIP41-like family zf-CCCH PF00642.19 GAK64980.1 - 2.7e-05 23.7 1.3 4.8e-05 22.9 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Suf PF05843.9 GAK64980.1 - 0.23 11.1 4.6 0.32 10.6 3.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-CCCH_2 PF14608.1 GAK64980.1 - 0.58 10.2 6.0 1.3 9.1 4.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type UPF0560 PF10577.4 GAK64980.1 - 0.73 8.0 9.2 1 7.5 6.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 WD40 PF00400.27 GAK64981.1 - 1.3e-22 78.7 9.2 0.00029 20.6 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Transglut_core2 PF13369.1 GAK64982.1 - 9.3e-15 54.4 0.0 1.5e-13 50.5 0.0 2.8 2 1 0 2 2 2 1 Transglutaminase-like superfamily YccV-like PF08755.6 GAK64982.1 - 2.7e-14 52.8 0.0 3.3e-11 43.0 0.0 2.9 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.2 GAK64982.1 - 2.4e-08 33.5 0.0 7.5e-08 31.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK64982.1 - 4.2e-05 23.0 0.0 0.00022 20.7 0.0 2.3 2 0 0 2 2 2 1 F-box domain Phe_ZIP PF08916.6 GAK64982.1 - 0.55 10.5 5.1 1.1 9.5 0.3 3.4 2 1 1 3 3 3 0 Phenylalanine zipper NOB1_Zn_bind PF08772.6 GAK64983.1 - 2.6e-31 107.2 2.1 5.4e-31 106.2 1.4 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-TFIIIC PF12660.2 GAK64983.1 - 0.027 14.3 0.6 0.15 12.0 0.2 2.2 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex AF1Q PF15017.1 GAK64983.1 - 0.31 10.9 5.7 0.54 10.1 3.0 2.1 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator OGG_N PF07934.7 GAK64984.1 - 2.2e-24 85.6 0.0 4.5e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 GAK64984.1 - 6.3e-15 55.3 0.0 2.5e-14 53.4 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAK64984.1 - 0.013 15.2 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif GLE1 PF07817.8 GAK64985.1 - 7.5e-73 244.6 0.0 1.2e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein Spore_coat_CotO PF14153.1 GAK64985.1 - 2.3 7.6 9.0 5.5 6.3 6.2 1.7 1 0 0 1 1 1 0 Spore coat protein CotO GRP PF07172.6 GAK64986.1 - 2.2 8.8 21.0 4 7.9 14.5 1.5 1 0 0 1 1 1 0 Glycine rich protein family DUF4141 PF13605.1 GAK64987.1 - 0.0061 15.7 0.5 0.01 15.0 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4141) AAA PF00004.24 GAK64989.1 - 2.3e-92 306.0 0.0 1.9e-46 157.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAK64989.1 - 4.6e-15 55.3 0.0 5e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAK64989.1 - 1.4e-11 44.3 0.7 0.00073 19.2 0.1 4.5 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAK64989.1 - 2.8e-11 43.6 0.8 0.0024 18.0 0.0 4.9 2 2 1 4 4 3 2 AAA domain AAA_2 PF07724.9 GAK64989.1 - 9.7e-11 41.8 0.0 0.00049 20.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 GAK64989.1 - 4.3e-10 39.6 0.0 0.0027 17.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAK64989.1 - 9.5e-10 39.3 0.0 9.6e-05 23.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAK64989.1 - 1.8e-09 37.8 11.4 0.0012 18.9 0.0 5.1 3 2 2 5 5 4 2 AAA ATPase domain TIP49 PF06068.8 GAK64989.1 - 5.9e-09 35.1 0.5 0.00022 20.0 0.0 2.8 2 1 1 3 3 3 2 TIP49 C-terminus AAA_14 PF13173.1 GAK64989.1 - 1.1e-08 34.9 0.0 0.0033 17.3 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 GAK64989.1 - 1.2e-07 31.3 0.4 0.03 14.0 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain Zeta_toxin PF06414.7 GAK64989.1 - 1.4e-07 30.8 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 GAK64989.1 - 3.4e-07 29.6 0.4 0.029 13.5 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAK64989.1 - 8.4e-07 28.5 0.7 0.012 15.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 GAK64989.1 - 8.6e-07 28.7 2.1 0.064 12.9 0.1 4.3 3 1 1 4 4 4 2 NACHT domain RNA_helicase PF00910.17 GAK64989.1 - 1.5e-06 28.2 0.0 0.059 13.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 GAK64989.1 - 3.4e-06 27.1 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 GAK64989.1 - 8.2e-06 26.1 0.0 0.031 14.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.6 GAK64989.1 - 1.2e-05 24.8 0.0 0.025 14.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAK64989.1 - 1.4e-05 24.5 6.5 0.77 9.1 0.1 4.5 2 2 2 4 4 4 2 AAA domain Sigma54_activ_2 PF14532.1 GAK64989.1 - 6.6e-05 22.9 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 GAK64989.1 - 0.00012 21.3 0.1 1.2 8.2 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.1 GAK64989.1 - 0.00013 22.2 0.0 0.7 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 GAK64989.1 - 0.00019 20.9 0.0 0.34 10.3 0.0 3.6 3 1 0 3 3 3 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 GAK64989.1 - 0.00022 21.1 0.0 0.074 12.9 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Viral_helicase1 PF01443.13 GAK64989.1 - 0.00046 19.7 0.0 0.81 9.1 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 GAK64989.1 - 0.00048 19.0 0.1 0.32 9.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain SKI PF01202.17 GAK64989.1 - 0.00099 19.0 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase PhoH PF02562.11 GAK64989.1 - 0.0013 18.0 0.6 1.1 8.3 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein DUF815 PF05673.8 GAK64989.1 - 0.0013 17.7 0.0 0.028 13.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 GAK64989.1 - 0.0059 16.3 0.0 1.7 8.2 0.0 3.0 2 2 1 3 3 3 1 Archaeal ATPase Rad17 PF03215.10 GAK64989.1 - 0.0077 14.9 0.0 2 7.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AFG1_ATPase PF03969.11 GAK64989.1 - 0.01 14.6 0.0 1.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase ResIII PF04851.10 GAK64989.1 - 0.011 15.6 0.0 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 GAK64989.1 - 0.014 15.0 0.0 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAK64989.1 - 0.014 15.0 0.1 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAK64989.1 - 0.015 14.9 0.2 6.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 GAK64989.1 - 0.016 14.0 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 GAK64989.1 - 0.021 14.5 0.1 2.7 7.6 0.0 2.7 2 1 1 3 3 2 0 NTPase PduV-EutP PF10662.4 GAK64989.1 - 0.16 11.4 0.0 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 GAK64989.1 - 0.26 10.8 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein TB2_DP1_HVA22 PF03134.14 GAK64990.1 - 4e-07 29.6 0.4 4e-07 29.6 0.3 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family IMS PF00817.15 GAK64991.1 - 3.6e-39 133.9 0.0 9.8e-39 132.5 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family Cyt-b5 PF00173.23 GAK64991.1 - 1.4e-23 82.4 0.1 6.1e-23 80.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMS_C PF11799.3 GAK64991.1 - 1.6e-19 70.0 0.0 3.7e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 GAK64991.1 - 0.028 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 GAK64991.1 - 0.11 12.5 0.0 0.48 10.5 0.0 2.2 1 0 0 1 1 1 0 IMS family HHH motif PCI_Csn8 PF10075.4 GAK64993.1 - 2.7e-31 108.2 0.1 4.9e-31 107.4 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 GAK64993.1 - 3.1e-28 98.7 0.1 5.7e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HAUS6_N PF14661.1 GAK64993.1 - 0.0029 17.0 9.5 0.0058 16.0 6.6 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus TRAPP PF04051.11 GAK64994.1 - 3.9e-40 136.8 0.0 4.8e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component He_PIG PF05345.7 GAK64995.1 - 5.3e-07 29.5 26.7 0.0008 19.3 1.8 5.0 4 1 0 4 4 4 3 Putative Ig domain PP2C PF00481.16 GAK64998.1 - 9.7e-32 110.3 0.0 9.4e-29 100.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 GAK64998.1 - 0.021 14.2 0.0 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C BrkDBD PF09607.5 GAK64998.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain NUDIX PF00293.23 GAK64999.1 - 8.1e-13 48.1 0.1 1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.24 GAK65000.1 - 3.6e-54 182.5 0.0 5.6e-38 130.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAK65000.1 - 1.5e-09 38.0 2.1 0.00025 21.1 0.2 4.1 3 2 1 4 4 3 2 AAA domain CDC48_2 PF02933.12 GAK65000.1 - 5.1e-09 35.6 0.1 6.4e-08 32.1 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 GAK65000.1 - 2.5e-08 34.1 0.0 0.0083 16.1 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 GAK65000.1 - 3.1e-08 33.4 0.1 0.0014 18.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAK65000.1 - 3.7e-08 33.3 0.0 0.001 18.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAK65000.1 - 4.1e-08 33.3 0.1 0.00031 20.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 GAK65000.1 - 3e-07 31.2 0.0 0.021 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 GAK65000.1 - 3.1e-07 29.6 0.1 0.0099 14.9 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 GAK65000.1 - 3.1e-07 30.3 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 GAK65000.1 - 4.3e-07 28.9 0.0 0.0059 15.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 GAK65000.1 - 4.4e-07 29.5 6.1 0.0095 15.6 0.2 3.4 4 0 0 4 4 2 2 Part of AAA domain NACHT PF05729.7 GAK65000.1 - 4.8e-07 29.5 0.2 0.028 14.0 0.0 3.5 3 1 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.12 GAK65000.1 - 1.1e-06 28.2 0.5 0.022 14.1 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAK65000.1 - 1.7e-06 27.3 0.8 0.0085 15.2 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 GAK65000.1 - 4e-06 26.5 2.3 0.015 14.9 0.1 2.7 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAK65000.1 - 5.4e-06 26.5 0.0 0.025 14.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 GAK65000.1 - 5.8e-06 26.6 0.1 0.033 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 GAK65000.1 - 2.1e-05 24.8 0.6 0.16 12.3 0.1 3.3 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 GAK65000.1 - 3.8e-05 23.6 0.0 0.068 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 GAK65000.1 - 5.2e-05 22.4 0.1 0.067 12.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin PhoH PF02562.11 GAK65000.1 - 5.9e-05 22.3 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 GAK65000.1 - 7.2e-05 22.5 0.6 0.28 10.8 0.1 3.7 2 2 1 4 4 4 1 Archaeal ATPase AAA_25 PF13481.1 GAK65000.1 - 7.8e-05 22.1 6.2 0.26 10.6 0.2 3.9 2 2 1 3 3 3 2 AAA domain NB-ARC PF00931.17 GAK65000.1 - 0.00015 20.7 0.1 0.34 9.7 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 GAK65000.1 - 0.00023 20.6 0.0 0.5 9.8 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 GAK65000.1 - 0.00039 19.5 0.1 0.11 11.5 0.0 2.6 2 0 0 2 2 2 1 KaiC AAA_11 PF13086.1 GAK65000.1 - 0.00052 19.6 0.0 0.69 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 GAK65000.1 - 0.00053 18.9 0.0 0.48 9.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 GAK65000.1 - 0.00061 19.4 0.0 0.44 10.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 GAK65000.1 - 0.00097 18.7 0.0 0.47 10.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 GAK65000.1 - 0.0012 17.8 0.1 0.37 9.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 GAK65000.1 - 0.0022 18.0 0.4 1.7 8.6 0.1 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 GAK65000.1 - 0.0026 17.3 0.0 0.67 9.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 GAK65000.1 - 0.0046 15.9 0.0 1.2 7.9 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DEAD PF00270.24 GAK65000.1 - 0.0088 15.5 0.6 17 4.8 0.0 3.8 3 1 1 4 4 4 0 DEAD/DEAH box helicase KTI12 PF08433.5 GAK65000.1 - 0.01 15.0 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.14 GAK65000.1 - 0.013 14.9 0.2 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 GAK65000.1 - 0.02 14.3 0.0 6.7 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain CDC48_N PF02359.13 GAK65000.1 - 0.022 14.7 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Zot PF05707.7 GAK65000.1 - 0.19 11.1 0.1 7.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) ResIII PF04851.10 GAK65000.1 - 0.22 11.3 0.2 18 5.1 0.0 2.9 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit TCTP PF00838.12 GAK65001.1 - 6.7e-65 218.0 0.2 9.4e-65 217.6 0.2 1.2 1 0 0 1 1 1 1 Translationally controlled tumour protein Zn_clus PF00172.13 GAK65002.1 - 5.1 7.1 9.3 1.4 8.8 1.2 2.3 1 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP PF00616.14 GAK65003.1 - 3.2e-33 115.0 0.0 6e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 GAK65003.1 - 1.3e-09 38.1 0.8 6.1e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain BAF1_ABF1 PF04684.8 GAK65003.1 - 0.36 9.6 22.8 0.6 8.8 15.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor LisH PF08513.6 GAK65005.1 - 2.3e-05 23.9 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 LisH Ribosomal_S13 PF00416.17 GAK65006.1 - 6.5e-24 84.4 0.0 8.4e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 GAK65006.1 - 0.0002 20.0 0.0 0.00034 19.2 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) EF-hand_1 PF00036.27 GAK65007.1 - 2.8e-27 91.8 11.5 1e-07 30.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAK65007.1 - 1.5e-24 85.8 3.6 1.4e-11 44.3 0.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAK65007.1 - 2.9e-21 73.7 13.1 2.4e-07 29.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 GAK65007.1 - 1.2e-20 71.5 8.3 1.6e-05 24.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 GAK65007.1 - 4.7e-16 58.1 12.3 1.4e-05 24.5 0.7 4.6 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAK65007.1 - 6.7e-06 26.1 0.0 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAK65007.1 - 2.3e-05 24.0 6.9 0.0056 16.3 0.2 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAK65007.1 - 2.9e-05 23.8 0.1 0.074 12.9 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain VCBS PF13517.1 GAK65007.1 - 0.018 15.3 0.6 8.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Proteasome PF00227.21 GAK65008.1 - 1.2e-43 148.6 0.2 1.3e-43 148.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Vac14_Fig4_bd PF11916.3 GAK65009.1 - 9.5e-81 269.2 8.6 8e-80 266.2 5.2 2.3 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 GAK65009.1 - 2.7e-44 149.5 0.0 3.1e-40 136.4 0.0 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 GAK65009.1 - 2.8e-13 48.7 7.5 0.00018 21.3 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 GAK65009.1 - 8.3e-10 38.8 4.1 0.21 11.8 0.0 5.7 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 GAK65009.1 - 2.8e-05 24.4 4.4 2 9.0 0.0 5.9 6 1 0 6 6 6 2 HEAT-like repeat MMS19_C PF12460.3 GAK65009.1 - 0.0021 16.8 0.5 0.026 13.2 0.0 2.6 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 GAK65009.1 - 0.0044 16.3 0.8 11 5.2 0.0 4.4 4 1 1 5 5 5 1 CLASP N terminal Cnd1 PF12717.2 GAK65009.1 - 0.0076 16.1 2.5 1.7 8.4 0.1 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 GAK65009.1 - 0.019 14.8 0.1 3.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein UCH PF00443.24 GAK65010.1 - 1.3e-53 181.9 0.0 1.9e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK65010.1 - 4.8e-22 78.7 0.0 9.6e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 GAK65010.1 - 0.015 14.5 0.0 1.4 8.1 0.0 2.9 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TBCA PF02970.11 GAK65011.1 - 2e-22 79.0 1.0 3.4e-22 78.3 0.7 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A Orbi_VP5 PF00901.12 GAK65011.1 - 0.036 12.2 0.8 0.04 12.1 0.5 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Myosin_tail_1 PF01576.14 GAK65011.1 - 0.055 11.2 1.9 0.061 11.0 1.3 1.0 1 0 0 1 1 1 0 Myosin tail RRM_1 PF00076.17 GAK65012.1 - 1.9e-27 94.6 0.1 2.5e-16 59.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65012.1 - 3.2e-13 49.4 0.0 1e-08 34.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK65012.1 - 6.9e-12 45.0 0.0 1.5e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAK65012.1 - 0.00024 20.7 0.0 0.001 18.7 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAK65012.1 - 0.00084 19.1 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Cpn60_TCP1 PF00118.19 GAK65013.1 - 5.7e-144 480.3 10.9 6.5e-144 480.1 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 GAK65013.1 - 0.0055 15.9 0.1 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Telomere recombination ATP-synt_Eps PF04627.8 GAK65013.1 - 5.7 6.5 5.4 3.8 7.1 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain LSM PF01423.17 GAK65014.1 - 9.8e-20 69.8 0.0 1.1e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAK65014.1 - 0.0032 17.3 0.0 0.0038 17.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_2 PF13347.1 GAK65015.1 - 2e-12 46.2 6.8 2e-12 46.2 4.7 2.5 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 GAK65015.1 - 1.8e-09 36.7 13.3 1.8e-09 36.7 9.2 3.1 3 1 0 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.10 GAK65015.1 - 2.9e-05 22.9 4.0 6.9e-05 21.7 2.7 1.6 1 0 0 1 1 1 1 PUCC protein Sugar_tr PF00083.19 GAK65015.1 - 0.002 16.8 0.1 0.002 16.8 0.1 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter zf-C2H2 PF00096.21 GAK65017.1 - 7.4e-05 22.8 10.1 0.034 14.5 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK65017.1 - 7.6e-05 22.8 13.6 0.00011 22.2 0.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAK65017.1 - 0.056 13.7 9.5 2.1 8.8 1.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.7 GAK65017.1 - 1.5 9.0 5.2 12 6.2 0.5 2.4 1 1 1 2 2 2 0 CHORD Aminotran_5 PF00266.14 GAK65018.1 - 3.2e-34 118.2 0.5 1.7e-26 92.8 0.1 2.3 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAK65018.1 - 1e-06 27.3 0.1 6.5e-06 24.6 0.0 2.1 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme zf-met2 PF12907.2 GAK65019.1 - 1.7e-08 34.2 4.5 3.1e-08 33.4 3.1 1.5 1 0 0 1 1 1 1 Zinc-binding zf-Di19 PF05605.7 GAK65019.1 - 0.001 19.1 2.2 0.0016 18.5 1.5 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding 4F5 PF04419.9 GAK65019.1 - 0.01 16.5 12.2 0.018 15.7 8.5 1.4 1 0 0 1 1 1 0 4F5 protein family zf-C2H2_4 PF13894.1 GAK65019.1 - 0.019 15.2 0.6 0.034 14.4 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DNA_Pol PF08996.5 GAK65019.1 - 0.12 11.7 0.4 0.14 11.5 0.2 1.3 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF1644 PF07800.7 GAK65019.1 - 0.14 11.9 1.8 0.31 10.8 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) MDM31_MDM32 PF08118.6 GAK65020.1 - 2.5e-127 425.4 6.6 4.8e-62 210.0 0.2 3.0 2 1 1 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M24 PF00557.19 GAK65021.1 - 5.7e-44 150.1 0.0 7.9e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 GAK65021.1 - 8.1e-19 68.4 0.2 2e-16 60.6 0.0 3.0 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Glyoxal_oxid_N PF07250.6 GAK65023.1 - 1e-34 119.6 0.1 4.8e-31 107.6 0.1 3.8 2 2 1 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 GAK65023.1 - 4.9e-20 71.4 0.5 1.1e-19 70.3 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) EphA2_TM PF14575.1 GAK65023.1 - 0.72 10.2 0.0 0.72 10.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 GAK65023.1 - 3 7.2 4.9 6 6.2 3.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_4 PF13418.1 GAK65023.1 - 5.8 6.7 8.4 16 5.3 0.2 4.0 5 0 0 5 5 5 0 Galactose oxidase, central domain Peroxidase_2 PF01328.12 GAK65024.1 - 1.2 7.7 3.6 0.84 8.2 0.8 1.8 1 1 1 2 2 2 0 Peroxidase, family 2 Ribosomal_L11_N PF03946.9 GAK65025.1 - 2.6e-18 65.2 0.1 4.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 GAK65025.1 - 8.3e-12 45.0 0.4 1.4e-11 44.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HnRNP_M PF11532.3 GAK65025.1 - 0.44 10.6 2.4 0.86 9.7 1.6 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Thymidylat_synt PF00303.14 GAK65026.1 - 4.4e-112 373.4 0.0 7.1e-112 372.7 0.0 1.3 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 GAK65026.1 - 2e-28 99.4 0.0 1.6e-27 96.5 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Sec23_trunk PF04811.10 GAK65027.1 - 1.1e-58 198.5 0.0 3.3e-58 196.9 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAK65027.1 - 1.8e-25 88.3 0.1 3.2e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAK65027.1 - 6.6e-20 71.4 0.0 1.4e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAK65027.1 - 1.2e-17 63.1 2.7 2.4e-17 62.1 1.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAK65027.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat peroxidase PF00141.18 GAK65028.1 - 1.1e-47 162.4 0.0 1.8e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase IGPS PF00218.16 GAK65029.1 - 2.1e-92 308.8 0.0 1.7e-91 305.8 0.0 2.1 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 GAK65029.1 - 7.9e-51 172.4 0.0 9.7e-45 152.5 0.0 2.2 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 GAK65029.1 - 1.3e-45 155.1 0.0 2.4e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAK65029.1 - 1.7e-05 24.3 0.1 5.4e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.13 GAK65029.1 - 8e-05 21.6 0.4 0.026 13.3 0.1 3.5 3 1 0 3 3 3 1 FMN-dependent dehydrogenase QRPTase_C PF01729.14 GAK65029.1 - 0.0037 16.8 0.1 0.02 14.4 0.0 2.2 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 GAK65029.1 - 0.0044 16.0 0.1 2.2 7.2 0.0 2.6 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase SMP PF04927.7 GAK65029.1 - 0.011 15.7 7.2 0.011 15.7 5.0 3.4 4 1 1 5 5 5 0 Seed maturation protein HEAT PF02985.17 GAK65030.1 - 6.6e-20 69.3 14.3 0.00037 20.3 0.0 10.3 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.1 GAK65030.1 - 2.8e-18 65.9 16.6 4.2e-08 33.3 0.0 7.4 3 2 3 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 GAK65030.1 - 2.6e-16 59.5 22.9 2.3e-08 34.2 0.0 8.5 7 1 2 9 9 9 5 HEAT-like repeat IBN_N PF03810.14 GAK65030.1 - 1.3e-10 41.0 0.4 1.4e-08 34.5 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 GAK65030.1 - 7.7e-08 31.8 10.6 0.0095 15.7 0.0 5.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 GAK65030.1 - 0.005 15.2 0.3 0.18 10.1 0.0 3.3 3 2 1 4 4 4 1 Adaptin N terminal region HEAT_PBS PF03130.11 GAK65030.1 - 0.015 15.7 4.6 25 5.7 0.0 5.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TIP120 PF08623.5 GAK65030.1 - 0.03 13.9 0.5 0.43 10.1 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) CLASP_N PF12348.3 GAK65030.1 - 0.042 13.2 0.1 55 3.0 0.0 4.0 4 1 1 5 5 5 0 CLASP N terminal Proteasom_PSMB PF10508.4 GAK65030.1 - 0.067 11.4 0.0 5.2 5.2 0.0 2.6 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit MMS19_N PF14500.1 GAK65030.1 - 0.14 11.3 0.4 2.3 7.4 0.0 2.7 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 GAK65030.1 - 0.27 9.9 0.2 4.1 6.0 0.0 2.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal Sugar_tr PF00083.19 GAK65031.1 - 2.3e-75 253.9 13.0 2.8e-75 253.6 9.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK65031.1 - 5.6e-20 71.3 13.5 5.6e-20 71.3 9.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4233 PF14017.1 GAK65031.1 - 3.3 7.6 14.0 0.23 11.4 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) CBP4 PF07960.6 GAK65032.1 - 9.8e-13 47.8 0.0 1.2e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4414 PF14377.1 GAK65032.1 - 0.0022 17.9 0.3 0.0025 17.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) DUF3098 PF11297.3 GAK65032.1 - 0.023 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) SIP PF04954.8 GAK65032.1 - 0.061 13.7 0.5 0.068 13.5 0.3 1.0 1 0 0 1 1 1 0 Siderophore-interacting protein DUF4574 PF15141.1 GAK65032.1 - 0.088 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) Pantoate_ligase PF02569.10 GAK65033.1 - 7.8e-81 270.8 0.0 1.1e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UPF0139 PF03669.8 GAK65034.1 - 0.011 15.2 0.1 0.016 14.7 0.0 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) STE3 PF02076.10 GAK65036.1 - 4.5e-50 170.3 8.5 2.4e-47 161.3 2.6 2.4 1 1 1 2 2 2 2 Pheromone A receptor DUF3184 PF11380.3 GAK65037.1 - 0.00012 20.2 0.0 0.024 12.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3184) Sen15 PF09631.5 GAK65038.1 - 7.3e-12 45.4 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Sen15 protein Polysacc_deac_1 PF01522.16 GAK65039.1 - 1.3e-05 24.8 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DAHP_synth_1 PF00793.15 GAK65040.1 - 2e-94 315.2 0.0 2.4e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_S19 PF00203.16 GAK65041.1 - 2e-23 81.8 0.0 2.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 OPT PF03169.10 GAK65042.1 - 4.4e-152 507.6 44.0 5.1e-152 507.4 30.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein UBACT PF02134.16 GAK65043.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein P16-Arc PF04699.9 GAK65044.1 - 6.2e-48 162.6 0.0 6.9e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) AviRa PF11599.3 GAK65044.1 - 0.0099 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa DUF1296 PF06972.6 GAK65044.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Fungal_trans PF04082.13 GAK65045.1 - 1.2e-12 47.2 0.0 2e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65045.1 - 2.8e-06 27.1 8.8 5e-06 26.3 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YkyA PF10368.4 GAK65045.1 - 0.78 9.0 0.2 1.1 8.5 0.1 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DEC-1_N PF04625.8 GAK65046.1 - 0.8 8.3 13.9 1 7.9 9.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ArfGap PF01412.13 GAK65052.1 - 3.7e-36 123.4 0.4 7.4e-36 122.4 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 GAK65052.1 - 9.4e-11 41.8 0.0 2e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 PH domain tRNA-synt_1c PF00749.16 GAK65053.1 - 3.3e-80 269.0 0.0 4.9e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Rft-1 PF04506.8 GAK65054.1 - 9.3e-75 252.0 0.0 3.8e-74 250.0 0.0 1.7 1 1 0 1 1 1 1 Rft protein SR-25 PF10500.4 GAK65057.1 - 0.032 13.7 10.1 0.045 13.2 7.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HrpB2 PF09487.5 GAK65057.1 - 0.041 14.0 1.2 1.1 9.4 0.1 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) Hex_IIIa PF02455.11 GAK65057.1 - 0.24 10.0 3.0 0.26 9.9 2.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF1117 PF06547.7 GAK65057.1 - 6.8 6.8 7.7 23 5.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1117) Kelch_3 PF13415.1 GAK65058.1 - 1.1e-16 60.4 8.4 0.00012 22.1 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAK65058.1 - 1.3e-14 53.7 0.5 0.0015 18.4 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAK65058.1 - 3.3e-13 49.1 1.2 0.00041 20.0 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAK65058.1 - 3.5e-09 36.4 0.0 0.052 13.7 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 GAK65058.1 - 2.3e-07 30.2 0.0 0.23 11.0 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAK65058.1 - 0.0085 15.8 0.0 0.14 11.9 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Gram_pos_anchor PF00746.16 GAK65058.1 - 0.089 12.6 1.0 0.24 11.2 0.7 1.8 1 0 0 1 1 1 0 Gram positive anchor Glyoxal_oxid_N PF07250.6 GAK65058.1 - 0.096 11.7 0.0 2 7.4 0.0 2.4 2 1 0 2 2 2 0 Glyoxal oxidase N-terminus Peptidase_M3 PF01432.15 GAK65059.1 - 3.8e-119 398.7 0.0 5.2e-119 398.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 E1-E2_ATPase PF00122.15 GAK65060.1 - 2.3e-19 69.3 0.0 1.8e-18 66.4 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAK65060.1 - 1.4e-16 61.5 0.0 2.9e-15 57.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAK65060.1 - 6.7e-12 45.9 0.0 1.6e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK65060.1 - 1.3e-05 25.0 0.0 3.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAK65060.1 - 0.0073 15.9 0.1 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Complex1_LYR PF05347.10 GAK65061.1 - 1.4e-05 24.7 0.2 2.5e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAK65061.1 - 0.00039 20.5 0.2 0.00081 19.5 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like zf-C2H2_2 PF12756.2 GAK65063.1 - 1.6e-35 121.2 1.5 1e-27 96.1 0.0 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 GAK65063.1 - 1.2e-09 38.0 5.1 4e-09 36.3 1.6 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAK65063.1 - 3.1e-09 36.7 18.4 2.5e-08 33.8 3.0 4.5 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 GAK65063.1 - 0.002 17.7 0.5 0.0076 15.8 0.3 2.0 1 0 0 1 1 1 1 DBF zinc finger AKAP95 PF04988.7 GAK65063.1 - 0.022 14.5 0.7 4.9 6.9 0.0 2.5 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 GAK65063.1 - 0.023 14.5 7.5 0.032 14.1 0.6 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 GAK65063.1 - 0.22 11.9 13.5 6.7 7.2 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Med3 PF11593.3 GAK65063.1 - 2.2 7.4 13.4 3.2 6.9 9.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-C2H2 PF00096.21 GAK65063.1 - 2.9 8.4 21.3 0.26 11.7 0.3 4.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK65063.1 - 6.8 7.1 10.3 7.6 7.0 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger double domain ubiquitin PF00240.18 GAK65064.1 - 6.2e-35 118.4 0.7 8.2e-35 118.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 GAK65064.1 - 3e-31 106.7 9.3 4.8e-31 106.1 6.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 GAK65064.1 - 6.4e-20 70.6 0.7 8.8e-20 70.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAK65064.1 - 8.2e-06 25.9 0.1 3e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAK65064.1 - 0.00017 21.3 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAK65064.1 - 0.0086 15.9 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAK65064.1 - 0.016 15.3 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 GAK65064.1 - 0.31 10.8 1.7 0.84 9.4 0.0 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 GAK65064.1 - 0.81 9.0 3.0 1.2 8.5 2.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase EF1G PF00647.14 GAK65065.1 - 9.2e-46 153.9 0.0 1.6e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain CPDase PF07823.6 GAK65065.1 - 2.4e-27 95.6 0.0 3.9e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein GST_N PF02798.15 GAK65065.1 - 2.6e-12 46.7 0.0 6.9e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAK65065.1 - 9.2e-11 41.8 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAK65065.1 - 4.2e-10 39.4 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAK65065.1 - 2.3e-07 30.5 0.0 5.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAK65065.1 - 2.8e-06 27.2 0.0 5.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAK65065.1 - 0.00014 22.3 0.0 0.00033 21.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Neisseria_TspB PF05616.8 GAK65065.1 - 5 5.3 10.8 7.8 4.7 7.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Thioredoxin PF00085.15 GAK65066.1 - 1.1e-60 201.8 1.2 1.3e-30 105.0 0.0 4.1 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 GAK65066.1 - 4.3e-38 130.9 0.4 1.4e-27 96.7 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAK65066.1 - 5.9e-13 48.7 0.2 0.001 19.1 0.0 4.6 4 1 1 5 5 5 3 Thioredoxin-like Thioredoxin_2 PF13098.1 GAK65066.1 - 2.9e-11 43.5 0.9 0.00095 19.3 0.0 4.0 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAK65066.1 - 1.4e-10 41.0 0.1 0.00075 19.4 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 GAK65066.1 - 9.7e-10 37.7 1.1 1.8e-09 36.8 0.8 1.3 1 0 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.16 GAK65066.1 - 6.2e-07 29.1 0.1 0.054 13.1 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_4 PF13462.1 GAK65066.1 - 1.4e-06 28.3 0.8 0.037 14.0 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin Redoxin PF08534.5 GAK65066.1 - 6.2e-05 22.5 2.2 0.016 14.7 0.0 3.0 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 GAK65066.1 - 0.0039 16.9 0.0 0.24 11.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Apc1 PF12859.2 GAK65067.1 - 1.7e-12 47.4 0.8 5e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 GAK65067.1 - 5.3e-11 42.1 12.7 0.08 13.2 0.0 6.6 6 0 0 6 6 6 5 Proteasome/cyclosome repeat UQ_con PF00179.21 GAK65068.1 - 1.4e-45 154.1 0.0 1.9e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAK65068.1 - 0.046 13.4 0.1 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B CAF1 PF04857.15 GAK65069.1 - 4.6e-65 219.5 0.0 6.6e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease VWA_2 PF13519.1 GAK65070.1 - 7e-16 58.8 0.1 7e-16 58.8 0.1 1.9 2 1 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 GAK65070.1 - 1.6e-11 42.7 15.0 3.6e-05 22.9 1.0 4.1 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 GAK65070.1 - 2.3e-10 40.3 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 GAK65070.1 - 2e-06 27.6 0.1 4e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain YjeF_N PF03853.10 GAK65070.1 - 0.039 13.5 0.5 0.1 12.2 0.1 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF4362 PF14275.1 GAK65070.1 - 0.078 13.0 0.2 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) MSP1_C PF07462.6 GAK65070.1 - 0.092 11.1 6.9 0.16 10.2 4.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-RanBP PF00641.13 GAK65071.1 - 0.00037 19.5 3.0 0.00073 18.5 2.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RhoGEF PF00621.15 GAK65072.1 - 1e-43 149.3 0.1 2.3e-43 148.1 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 GAK65072.1 - 1.1e-40 138.4 0.0 2.4e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 GAK65072.1 - 3.4e-34 116.7 0.1 6.2e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 GAK65072.1 - 4.5e-08 32.6 0.0 1.2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 GAK65072.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 PH domain AAA PF00004.24 GAK65074.1 - 2.5e-61 205.6 0.0 7.2e-45 152.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAK65074.1 - 3.5e-08 34.2 0.0 0.0081 16.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 GAK65074.1 - 2e-07 31.1 8.6 0.0091 15.9 0.1 5.6 4 1 1 5 5 5 2 AAA ATPase domain AAA_5 PF07728.9 GAK65074.1 - 1e-06 28.5 0.1 0.017 14.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAK65074.1 - 3.4e-06 26.9 0.0 0.035 14.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 GAK65074.1 - 4.6e-06 26.7 0.5 0.0055 16.8 0.0 4.0 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 GAK65074.1 - 3.7e-05 22.8 0.0 0.0054 15.8 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 GAK65074.1 - 6.1e-05 22.5 0.7 0.002 17.5 0.1 3.2 2 1 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 GAK65074.1 - 6.5e-05 22.9 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.1 GAK65074.1 - 8.5e-05 22.4 0.0 0.2 11.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain SKI PF01202.17 GAK65074.1 - 8.9e-05 22.4 1.1 0.052 13.4 0.0 3.2 3 1 0 3 3 2 1 Shikimate kinase IstB_IS21 PF01695.12 GAK65074.1 - 0.00073 19.0 0.2 0.0032 16.8 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 GAK65074.1 - 0.00085 18.8 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 GAK65074.1 - 0.00099 19.1 0.0 0.19 11.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAK65074.1 - 0.0011 17.7 0.0 0.031 12.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 GAK65074.1 - 0.0013 18.4 9.7 0.0067 16.1 0.0 4.8 4 0 0 4 4 4 1 Part of AAA domain DUF815 PF05673.8 GAK65074.1 - 0.0018 17.2 0.0 1.6 7.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 GAK65074.1 - 0.002 17.3 0.1 0.046 12.8 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 GAK65074.1 - 0.0021 17.2 0.1 0.0058 15.7 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_2 PF07724.9 GAK65074.1 - 0.0024 17.8 0.0 0.015 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 GAK65074.1 - 0.0031 17.8 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAK65074.1 - 0.0032 17.1 0.1 3.1 7.4 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Vps4_C PF09336.5 GAK65074.1 - 0.0033 17.2 0.0 0.12 12.3 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 GAK65074.1 - 0.0051 16.9 0.0 0.079 13.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.12 GAK65074.1 - 0.0081 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 GAK65074.1 - 0.015 14.9 0.0 0.53 9.8 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 GAK65074.1 - 0.018 14.2 0.0 0.075 12.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 GAK65074.1 - 0.03 13.9 0.0 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 GAK65074.1 - 0.033 13.2 0.0 0.5 9.4 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin CDC48_2 PF02933.12 GAK65074.1 - 0.037 13.6 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 NB-ARC PF00931.17 GAK65074.1 - 0.047 12.5 0.0 1.4 7.6 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.1 GAK65074.1 - 0.052 13.1 0.2 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 GAK65074.1 - 0.074 12.9 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family OAD_gamma PF04277.8 GAK65074.1 - 0.31 11.4 8.3 0.4 11.0 2.3 2.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RRM_1 PF00076.17 GAK65075.1 - 5.9e-35 118.7 0.0 2.3e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65075.1 - 3.2e-28 97.5 0.0 1.6e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK65075.1 - 1.8e-10 40.5 0.0 9.6e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4446 PF14584.1 GAK65075.1 - 0.091 12.5 0.2 0.21 11.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) RhoGEF PF00621.15 GAK65078.1 - 2.8e-43 147.8 0.0 4.9e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 GAK65078.1 - 4.9e-18 64.8 10.2 8.6e-18 64.0 7.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 GAK65078.1 - 7.1e-10 39.0 0.0 1.5e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAK65078.1 - 0.22 11.8 0.0 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain FYVE_2 PF02318.11 GAK65078.1 - 1.4 8.8 6.4 2.9 7.8 4.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger SOBP PF15279.1 GAK65079.1 - 1.7 8.9 15.8 2.2 8.6 10.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.14 GAK65079.1 - 2.1 6.1 13.8 2.7 5.7 9.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 GAK65079.1 - 2.4 6.3 29.1 3 6.0 20.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 GAK65079.1 - 6.2 4.4 13.4 7.6 4.1 9.3 1.1 1 0 0 1 1 1 0 Ycf1 Fasciclin PF02469.17 GAK65079.1 - 6.4 6.8 10.3 6.5 6.7 6.0 1.9 2 1 1 3 3 3 0 Fasciclin domain ASF1_hist_chap PF04729.8 GAK65080.1 - 9.1e-66 220.2 0.1 1.1e-65 219.9 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Dus PF01207.12 GAK65081.1 - 4.1e-42 144.0 0.0 4.1e-22 78.4 0.0 3.2 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) Zn_clus PF00172.13 GAK65082.1 - 3.6e-09 36.3 11.4 5.8e-09 35.7 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSG PF02349.10 GAK65082.1 - 0.13 12.2 8.7 0.2 11.6 6.0 1.1 1 0 0 1 1 1 0 Major surface glycoprotein eIF-5a PF01287.15 GAK65083.1 - 2.8e-27 94.4 0.2 4e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 GAK65083.1 - 0.00034 20.2 0.5 0.00073 19.1 0.4 1.6 1 0 0 1 1 1 1 KOW motif HLH PF00010.21 GAK65084.1 - 1.1e-12 47.3 0.2 2.1e-12 46.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhaP_Bmeg PF09602.5 GAK65084.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1620 PF07774.8 GAK65085.1 - 1.8e-57 194.1 0.0 2.7e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 GAK65085.1 - 4.4e-10 39.4 5.3 4e-06 26.4 0.5 4.0 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 GAK65085.1 - 1.5e-05 24.2 0.0 1.1 8.8 0.0 5.1 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.1 GAK65085.1 - 0.32 11.3 5.8 4.5 7.6 0.0 5.4 6 0 0 6 6 6 0 PQQ-like domain Zn_clus PF00172.13 GAK65086.1 - 8.8e-09 35.1 10.8 1.6e-08 34.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb2_6 PF00562.23 GAK65087.1 - 1.7e-117 392.4 0.0 2.6e-117 391.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAK65087.1 - 6.3e-60 201.5 0.2 1.4e-59 200.4 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 GAK65087.1 - 6.9e-36 123.4 0.3 1.3e-35 122.5 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 GAK65087.1 - 1e-27 96.2 0.1 2.5e-27 94.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 GAK65087.1 - 2e-24 85.1 2.2 1e-23 82.8 0.5 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 GAK65087.1 - 1.1e-20 73.1 0.0 2.7e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 GAK65087.1 - 1.2e-11 44.4 1.0 2.9e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Metallophos PF00149.23 GAK65088.1 - 1e-42 145.7 0.1 1.7e-42 145.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RrnaAD PF00398.15 GAK65089.1 - 1.3e-55 188.3 0.0 1.7e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAK65089.1 - 7.3e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK65089.1 - 0.00021 20.7 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAK65089.1 - 0.00081 19.9 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK65089.1 - 0.0013 19.1 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAK65089.1 - 0.0036 16.5 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 GAK65089.1 - 0.0039 17.6 0.0 0.0081 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK65089.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAK65089.1 - 0.009 15.1 0.0 0.022 13.8 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 GAK65089.1 - 0.0099 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 GAK65089.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 GAK65089.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAK65089.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.15 GAK65090.1 - 2.6e-151 504.5 4.7 3.3e-151 504.1 3.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 GAK65090.1 - 4.9e-27 94.9 0.6 5.3e-24 85.0 0.0 3.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAK65090.1 - 4.4e-18 65.3 5.2 1e-05 25.7 0.0 5.6 2 1 1 4 4 4 4 HEAT repeats HEAT PF02985.17 GAK65090.1 - 4.2e-10 38.8 0.3 0.0087 16.0 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 GAK65090.1 - 2.3e-06 27.8 2.7 0.031 14.7 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 GAK65090.1 - 0.00096 18.5 0.0 2.1 7.6 0.0 3.0 3 0 0 3 3 3 2 CLASP N terminal Lyase_1 PF00206.15 GAK65091.1 - 2.7e-23 82.6 0.0 4.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 GAK65091.1 - 5e-16 58.4 0.0 1.1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Adaptin_binding PF10199.4 GAK65092.1 - 2.8e-24 85.9 0.0 6.9e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Sod_Fe_C PF02777.13 GAK65093.1 - 8.4e-36 122.0 0.1 1.4e-35 121.3 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 GAK65093.1 - 4.5e-32 110.1 3.7 7.3e-32 109.4 2.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Mus7 PF09462.5 GAK65094.1 - 7e-156 520.6 0.0 9.1e-156 520.2 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family DUF4140 PF13600.1 GAK65095.1 - 0.13 12.7 3.3 3.4 8.1 0.4 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Membr_traf_MHD PF10540.4 GAK65096.1 - 2.4e-18 66.2 0.7 1.8e-16 60.1 0.1 2.9 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 GAK65096.1 - 1.2e-07 31.4 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Nucleos_tra2_C PF07662.8 GAK65096.1 - 0.086 12.3 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus ATP-synt_E PF05680.7 GAK65096.1 - 3.5 7.6 10.1 1 9.3 0.0 3.4 3 0 0 3 3 3 0 ATP synthase E chain 60KD_IMP PF02096.15 GAK65098.1 - 7.9e-42 143.1 0.5 1.2e-41 142.6 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Aa_trans PF01490.13 GAK65100.1 - 1.2e-20 73.3 33.7 1.5e-20 73.0 23.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein F-box-like PF12937.2 GAK65101.1 - 2.3e-10 40.0 0.1 4.8e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF3506 PF12014.3 GAK65101.1 - 9e-09 35.2 0.0 3.2e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box PF00646.28 GAK65101.1 - 0.0003 20.3 0.0 0.0008 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 GAK65102.1 - 6.9e-16 57.4 5.2 0.00042 20.0 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat VHS PF00790.14 GAK65103.1 - 1.3e-14 54.0 0.0 2.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 VHS domain HTH_IclR PF09339.5 GAK65103.1 - 0.021 14.4 0.1 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ras PF00071.17 GAK65104.1 - 4.6e-59 198.4 0.0 5.5e-59 198.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK65104.1 - 2.5e-19 69.9 0.0 4.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK65104.1 - 2.7e-12 46.2 0.0 3.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAK65104.1 - 6e-07 29.0 0.0 1.1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAK65104.1 - 2.8e-06 26.6 0.0 3.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAK65104.1 - 1.8e-05 24.6 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAK65104.1 - 0.0045 17.1 0.1 0.57 10.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAK65104.1 - 0.026 14.4 0.8 0.11 12.4 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 GAK65104.1 - 0.049 12.8 0.1 0.12 11.5 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function, DUF258 SRPRB PF09439.5 GAK65104.1 - 0.12 11.5 0.1 0.39 9.8 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NIF3 PF01784.13 GAK65105.1 - 2.4e-63 213.9 0.0 3e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COPIIcoated_ERV PF07970.7 GAK65106.1 - 3.8e-36 124.8 0.1 5.9e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAK65106.1 - 1.5e-23 82.5 0.1 2.9e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RNA_pol_A_bac PF01000.21 GAK65107.1 - 3.6e-28 97.9 0.0 6.4e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAK65107.1 - 8.9e-16 56.7 0.0 1.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_C65 PF10275.4 GAK65108.1 - 3.3e-72 242.7 0.0 3.8e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 GAK65108.1 - 0.0021 18.6 0.0 0.023 15.2 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease Fungal_trans PF04082.13 GAK65109.1 - 1.8e-15 56.5 0.1 3.5e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65109.1 - 3.6e-05 23.5 11.0 5.5e-05 22.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_dim PF02852.17 GAK65110.1 - 4.6e-42 142.5 1.5 7.5e-42 141.8 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 GAK65110.1 - 9.7e-39 133.3 13.0 1.5e-28 100.0 2.9 3.5 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK65110.1 - 4.1e-19 68.7 9.2 4.6e-16 59.0 1.4 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAK65110.1 - 3.3e-11 42.9 4.3 9.9e-11 41.3 0.2 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAK65110.1 - 7.2e-10 39.2 4.7 5e-05 23.4 1.1 3.3 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAK65110.1 - 2e-08 33.5 8.4 8.3e-07 28.1 2.7 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 GAK65110.1 - 1.3e-07 30.9 3.2 0.00044 19.4 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 GAK65110.1 - 3e-07 29.6 2.3 3e-07 29.6 1.6 3.7 3 1 1 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.1 GAK65110.1 - 4e-07 29.9 4.9 0.00034 20.5 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAK65110.1 - 1.3e-06 27.1 13.1 0.00039 19.0 0.6 4.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.14 GAK65110.1 - 1.5e-05 24.2 8.6 0.049 12.6 0.0 3.3 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 GAK65110.1 - 1.9e-05 23.7 0.4 0.11 11.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAK65110.1 - 9.1e-05 21.5 12.4 0.0057 15.5 0.1 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 GAK65110.1 - 0.00018 21.1 3.5 0.056 13.0 0.1 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAK65110.1 - 0.97 8.2 7.4 0.68 8.7 0.5 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 GAK65110.1 - 4.4 6.9 9.6 0.099 12.2 0.7 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PsbI PF02532.9 GAK65111.1 - 0.73 9.5 2.9 0.97 9.1 0.0 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) UQ_con PF00179.21 GAK65113.1 - 5.4e-34 116.6 0.0 6.6e-34 116.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L18ae PF01775.12 GAK65114.1 - 4.1e-59 197.9 2.0 4.9e-59 197.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain RRM_6 PF14259.1 GAK65116.1 - 1.5e-09 37.7 0.0 2.3e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAK65116.1 - 8.5e-07 28.6 0.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.12 GAK65116.1 - 9.5e-07 28.8 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 GAK65116.1 - 1.5e-06 27.7 4.1 2.7e-06 26.9 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 GAK65116.1 - 2.4e-06 27.2 0.1 6.9e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK65116.1 - 0.00013 21.5 0.1 0.31 10.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Seryl_tRNA_N PF02403.17 GAK65116.1 - 0.43 10.6 13.4 0.027 14.4 3.5 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COX5A PF02284.11 GAK65117.1 - 3.7e-39 133.0 0.1 6.1e-39 132.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Adap_comp_sub PF00928.16 GAK65118.1 - 1.5e-20 73.4 0.0 2.3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAK65118.1 - 2.6e-05 23.9 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TT_ORF2 PF02957.10 GAK65118.1 - 0.19 12.4 1.0 0.35 11.5 0.1 1.8 1 1 1 2 2 2 0 TT viral ORF2 RRM_1 PF00076.17 GAK65121.1 - 1.9e-18 65.8 0.3 1.2e-09 37.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK65121.1 - 6.6e-16 57.9 0.0 6.8e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65121.1 - 1.4e-10 41.0 0.1 3.5e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAK65121.1 - 0.0015 18.2 0.1 0.088 12.5 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 GAK65123.1 - 2.9e-22 78.0 0.0 4.1e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65123.1 - 1.5e-18 66.4 0.0 2.7e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK65123.1 - 1.4e-11 44.0 0.0 2.8e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAK65123.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif GRP PF07172.6 GAK65123.1 - 4.3 7.8 10.8 9.8 6.7 7.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family RRM_1 PF00076.17 GAK65124.1 - 1.9e-12 46.6 0.0 3.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65124.1 - 6.3e-09 35.6 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK65124.1 - 7.5e-06 25.7 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAK65124.1 - 0.0029 17.3 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SET PF00856.23 GAK65125.1 - 1.2e-12 48.4 0.0 1.9e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 SET domain NST1 PF13945.1 GAK65126.1 - 2.9e-50 170.9 1.2 2.9e-50 170.9 0.8 5.7 3 2 1 5 5 5 3 Salt tolerance down-regulator SPX PF03105.14 GAK65126.1 - 4.5 6.9 0.0 4.5 6.9 0.0 3.7 2 1 1 3 3 3 0 SPX domain Mid1 PF12929.2 GAK65129.1 - 1.8e-71 241.1 3.6 2.3e-71 240.7 2.5 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component fn3 PF00041.16 GAK65129.1 - 0.043 13.9 0.9 0.27 11.4 0.0 2.5 3 0 0 3 3 3 0 Fibronectin type III domain Fz PF01392.17 GAK65129.1 - 0.05 13.9 2.1 0.16 12.3 0.2 2.3 2 0 0 2 2 2 0 Fz domain ABC1 PF03109.11 GAK65130.1 - 1.1e-29 102.8 0.0 2e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.4 GAK65130.1 - 6.5e-19 67.1 0.2 6.5e-19 67.1 0.2 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal PPV_E2_C PF00511.12 GAK65130.1 - 0.21 11.5 0.2 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 E2 (early) protein, C terminal Lipase_3 PF01764.20 GAK65131.1 - 3.2e-16 59.2 0.0 5.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 GAK65131.1 - 0.039 13.5 0.0 0.085 12.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 GAK65131.1 - 0.042 13.2 0.1 0.3 10.4 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) MFS_1 PF07690.11 GAK65133.1 - 7.4e-26 90.6 43.6 7.4e-26 90.6 30.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 GAK65133.1 - 7 4.5 11.2 0.18 9.8 0.8 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Gp_dh_C PF02800.15 GAK65134.1 - 1.3e-75 252.1 0.0 1.9e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 GAK65134.1 - 1.3e-53 181.0 0.1 2.6e-53 180.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TauD PF02668.11 GAK65135.1 - 1e-28 100.7 0.0 2.3e-28 99.5 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RNA_pol PF00940.14 GAK65136.1 - 2.4e-157 523.5 0.0 3.6e-157 523.0 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 GAK65136.1 - 3.9e-83 279.3 3.6 6.6e-83 278.5 2.5 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 GAK65136.1 - 0.0013 18.6 0.0 0.061 13.3 0.0 2.8 2 1 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 GAK65136.1 - 0.011 15.9 1.6 6.1 7.4 0.1 4.5 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Ras PF00071.17 GAK65137.1 - 2.1e-50 170.3 0.0 2.4e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK65137.1 - 4.1e-17 62.7 0.0 5.7e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK65137.1 - 3.5e-06 26.3 0.0 5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAK65137.1 - 0.021 14.2 0.0 0.089 12.2 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAK65137.1 - 0.032 13.7 0.0 4.2 6.8 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 GAK65137.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PCI PF01399.22 GAK65138.1 - 1.3e-10 41.4 0.0 4.1e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 PCI domain Amidohydro_3 PF07969.6 GAK65139.1 - 7.2e-66 223.0 3.0 1.1e-65 222.4 2.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Methyltransf_23 PF13489.1 GAK65139.1 - 4.7e-09 36.1 0.0 1.3e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK65139.1 - 1.1e-08 34.7 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK65139.1 - 4.3e-08 33.7 0.0 1.5e-07 31.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK65139.1 - 2e-07 31.3 0.0 3.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK65139.1 - 0.00015 22.0 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK65139.1 - 0.00019 21.8 0.0 0.00051 20.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK65139.1 - 0.00037 20.4 0.1 0.0011 18.9 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK65139.1 - 0.00088 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 GAK65139.1 - 0.0027 18.5 0.0 0.0095 16.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAK65139.1 - 0.0031 16.6 0.0 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Amidohydro_1 PF01979.15 GAK65139.1 - 0.038 13.6 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase family Amidohydro_5 PF13594.1 GAK65139.1 - 0.043 13.6 0.1 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase RrnaAD PF00398.15 GAK65139.1 - 0.084 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 GAK65139.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF444 PF04285.7 GAK65140.1 - 0.099 11.2 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DUF1289 PF06945.8 GAK65140.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) FA_desaturase PF00487.19 GAK65141.1 - 1.2e-30 106.7 26.9 3.2e-30 105.4 18.6 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAK65141.1 - 2.1e-12 46.6 0.0 5e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UPF0203 PF05254.7 GAK65142.1 - 0.00078 19.2 2.1 0.002 17.9 1.5 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) DUF3551 PF12071.3 GAK65142.1 - 0.037 13.5 0.9 0.045 13.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) CHCH PF06747.8 GAK65142.1 - 0.048 13.6 1.8 0.51 10.3 1.1 2.1 1 1 1 2 2 2 0 CHCH domain NDUF_B7 PF05676.8 GAK65142.1 - 0.081 12.3 1.0 2 7.8 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.12 GAK65142.1 - 0.1 12.6 2.5 0.15 12.0 1.7 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 GAK65142.1 - 0.11 12.3 0.5 0.14 12.1 0.4 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 GAK65142.1 - 0.17 11.7 4.0 0.52 10.1 2.8 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydrolase_6 PF12697.2 GAK65143.1 - 1.3e-15 57.8 1.7 1.9e-15 57.4 0.4 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK65143.1 - 1.8e-10 40.7 0.0 3.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK65143.1 - 0.00073 19.3 0.0 0.011 15.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 GAK65144.1 - 0.21 10.6 0.0 0.21 10.6 0.0 2.0 2 1 0 2 2 2 0 Protein kinase domain Pkinase_C PF00433.19 GAK65144.1 - 0.23 11.9 5.3 0.063 13.8 0.8 2.3 2 0 0 2 2 2 0 Protein kinase C terminal domain SET PF00856.23 GAK65145.1 - 9.6e-24 84.5 0.0 9.6e-24 84.5 0.0 3.4 2 2 0 2 2 2 1 SET domain SRI PF08236.6 GAK65145.1 - 1.3e-19 69.8 1.4 3.1e-19 68.7 0.9 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain DUF2217 PF10265.4 GAK65145.1 - 3.9 6.1 7.9 7.3 5.2 5.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) WD40 PF00400.27 GAK65146.1 - 5.8e-18 64.0 1.9 3.5e-08 33.0 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAK65146.1 - 0.006 16.0 0.0 0.042 13.3 0.0 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 GAK65146.1 - 0.038 13.6 0.4 1.4 8.6 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 GAK65146.1 - 0.043 12.9 0.1 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal MFS_1 PF07690.11 GAK65147.1 - 6e-18 64.6 33.3 6e-18 64.6 23.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 GAK65147.1 - 7e-15 54.8 5.9 1.8e-14 53.5 4.1 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Abhydrolase_3 PF07859.8 GAK65148.1 - 7.9e-50 169.3 0.0 1.1e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAK65148.1 - 5e-07 28.8 3.3 6.4e-06 25.1 2.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAK65148.1 - 1.4e-05 24.8 0.1 2e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK65148.1 - 9.1e-05 21.7 0.1 0.013 14.7 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAK65148.1 - 0.00092 19.1 1.4 0.0018 18.2 1.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 GAK65148.1 - 0.0031 16.8 0.1 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region AXE1 PF05448.7 GAK65148.1 - 0.0046 15.4 0.1 0.037 12.5 0.1 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) HsbA PF12296.3 GAK65149.1 - 6.2e-10 39.0 0.2 1.1e-09 38.2 0.2 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1045 PF06299.7 GAK65149.1 - 0.28 10.8 1.6 0.22 11.1 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) DUF4499 PF14934.1 GAK65150.1 - 0.087 12.7 0.9 0.19 11.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4499) DUF1929 PF09118.6 GAK65151.1 - 5.7e-22 77.6 0.5 1.7e-21 76.1 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.21 GAK65151.1 - 9.8e-18 63.6 23.4 2.9e-06 26.9 0.9 4.4 4 0 0 4 4 4 4 PAN domain PAN_4 PF14295.1 GAK65151.1 - 3.1e-11 42.7 31.8 0.00011 21.8 1.0 4.9 4 0 0 4 4 4 4 PAN domain Kelch_4 PF13418.1 GAK65151.1 - 7.2e-11 41.6 10.0 9.3e-05 22.1 0.4 5.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 GAK65151.1 - 8.4e-08 31.5 1.2 0.0093 15.0 0.0 2.9 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_6 PF13964.1 GAK65151.1 - 9.1e-08 31.9 14.6 0.00016 21.7 0.0 5.9 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.20 GAK65151.1 - 1.7e-07 30.6 9.6 0.00022 20.7 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAK65151.1 - 0.0013 18.3 7.0 0.65 9.8 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Prot_inhib_II PF02428.10 GAK65151.1 - 0.012 15.6 30.6 0.49 10.4 0.6 5.5 4 3 0 4 4 4 0 Potato type II proteinase inhibitor family Kelch_3 PF13415.1 GAK65151.1 - 0.018 15.1 9.1 2.2 8.5 0.1 5.5 6 0 0 6 6 6 0 Galactose oxidase, central domain Sugar_tr PF00083.19 GAK65152.1 - 8.7e-104 347.5 25.7 1e-103 347.3 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK65152.1 - 3.9e-20 71.8 35.8 1.4e-19 70.0 5.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.17 GAK65153.1 - 1.2e-34 119.3 0.0 1.4e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.13 GAK65154.1 - 5.2e-09 35.8 9.0 8.6e-09 35.1 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK65154.1 - 1.3e-08 34.0 0.0 2.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CheZ PF04344.8 GAK65154.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF2306 PF10067.4 GAK65155.1 - 5.8e-05 23.1 8.0 0.017 15.1 5.6 3.0 1 1 0 1 1 1 1 Predicted membrane protein (DUF2306) SdpI PF13630.1 GAK65155.1 - 0.15 11.8 2.0 0.99 9.1 0.2 3.0 3 0 0 3 3 3 0 SdpI/YhfL protein family ATG22 PF11700.3 GAK65156.1 - 9.3e-42 143.0 19.9 1.2e-41 142.7 13.8 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like PAN_4 PF14295.1 GAK65157.1 - 0.032 13.9 1.3 0.067 12.9 0.9 1.5 1 0 0 1 1 1 0 PAN domain Fungal_trans PF04082.13 GAK65159.1 - 6.6e-22 77.6 0.0 1.4e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65159.1 - 3.6e-09 36.3 11.0 6.9e-09 35.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 GAK65160.1 - 8.8e-11 42.2 0.0 2.2e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAK65160.1 - 4.3e-06 25.4 0.0 0.16 10.4 0.1 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 GAK65160.1 - 0.005 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.14 GAK65161.1 - 1.3e-18 67.1 2.0 9.9e-18 64.3 1.4 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAK65161.1 - 2.8e-15 56.1 3.2 5.9e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAK65161.1 - 2.5e-06 26.4 0.4 0.009 14.6 0.0 2.6 3 0 0 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.19 GAK65161.1 - 1.2e-05 24.5 0.7 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAK65161.1 - 3.8e-05 23.6 0.7 0.00015 21.7 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAK65161.1 - 0.00025 20.0 4.1 0.16 10.8 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAK65161.1 - 0.00046 19.1 1.9 0.001 18.0 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAK65161.1 - 0.00084 17.9 0.7 0.02 13.4 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAK65161.1 - 0.00091 19.1 0.0 0.0045 16.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK65161.1 - 0.002 18.2 0.1 0.011 15.8 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK65161.1 - 0.0067 16.7 0.2 0.39 11.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK65161.1 - 0.0085 15.2 0.0 0.037 13.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family SE PF08491.5 GAK65161.1 - 0.018 13.9 0.0 0.044 12.6 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.2 GAK65161.1 - 0.098 11.7 3.3 0.22 10.5 2.3 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 GAK65161.1 - 0.11 11.3 0.1 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 GAK65161.1 - 0.13 11.6 0.2 0.32 10.4 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 GAK65161.1 - 0.14 11.9 0.7 15 5.3 0.1 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 GAK65162.1 - 1.3e-25 89.8 36.9 2.1e-24 85.9 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK65162.1 - 3.8e-10 38.9 16.1 3.8e-10 38.9 11.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAK65162.1 - 1.7e-07 29.8 5.1 2.9e-07 29.0 3.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAK65163.1 - 3.2e-85 286.3 17.1 3.9e-85 286.1 11.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK65163.1 - 1.5e-20 73.2 24.5 6.8e-17 61.1 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAK65163.1 - 0.00047 18.6 2.0 0.00047 18.6 1.4 3.7 2 2 2 4 4 4 2 MFS/sugar transport protein Alpha-amylase PF00128.19 GAK65165.1 - 1.8e-100 336.3 0.4 2.7e-100 335.8 0.3 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_42C PF08533.5 GAK65165.1 - 0.0015 18.0 0.1 0.0049 16.3 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain hDGE_amylase PF14701.1 GAK65165.1 - 0.0016 17.4 0.1 0.0031 16.4 0.1 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 GAK65165.1 - 0.027 14.5 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Glyoxalase_2 PF12681.2 GAK65165.1 - 0.056 14.0 0.0 2.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Glyoxalase-like domain Gln-synt_C PF00120.19 GAK65166.1 - 1.3e-49 168.6 0.0 1.1e-48 165.5 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Mito_fiss_reg PF05308.6 GAK65166.1 - 1.7 7.9 4.2 2.8 7.2 2.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Aldedh PF00171.17 GAK65167.1 - 1.2e-129 432.6 0.1 1.3e-129 432.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK65167.1 - 0.00036 19.3 0.1 0.0047 15.6 0.1 2.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short PF00106.20 GAK65168.1 - 2.6e-26 92.5 1.1 3.4e-26 92.1 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK65168.1 - 1.1e-21 77.7 0.0 1.3e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK65168.1 - 5.3e-08 32.7 0.4 1e-07 31.8 0.3 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAK65168.1 - 0.00052 19.7 0.2 0.0019 17.8 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAK65168.1 - 0.082 12.2 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OPT PF03169.10 GAK65169.1 - 2.7e-134 448.9 47.5 3.1e-134 448.7 32.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 GAK65169.1 - 1.6 7.7 3.7 0.52 9.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) FAD_binding_3 PF01494.14 GAK65170.1 - 2.5e-20 72.8 0.0 4.9e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAK65170.1 - 2.1e-06 26.8 0.1 3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK65170.1 - 4e-06 26.7 0.9 9.6e-06 25.5 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAK65170.1 - 6.9e-06 25.2 0.0 9.2e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAK65170.1 - 2.4e-05 24.3 0.2 4.6e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAK65170.1 - 0.00045 19.1 2.3 0.0013 17.6 1.2 2.0 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 GAK65170.1 - 0.00067 18.8 0.0 0.00089 18.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAK65170.1 - 0.0061 16.9 0.2 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAK65170.1 - 0.04 12.5 0.3 0.29 9.6 0.2 2.2 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.11 GAK65170.1 - 0.049 13.0 0.9 8.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 GAK65170.1 - 0.07 13.1 0.0 0.29 11.1 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAK65170.1 - 0.079 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 GAK65170.1 - 0.1 11.4 3.7 0.075 11.8 1.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAK65170.1 - 0.14 10.5 0.6 0.25 9.7 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.13 GAK65171.1 - 3.6e-09 35.8 2.2 8e-09 34.7 1.5 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65171.1 - 3.9e-07 29.8 9.6 7e-07 29.0 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAK65171.1 - 0.42 10.7 7.6 1.1 9.4 5.2 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region EthD PF07110.6 GAK65172.1 - 5e-18 65.8 0.2 8.5e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 EthD domain COesterase PF00135.23 GAK65173.1 - 1.1e-94 318.1 1.5 1.8e-94 317.4 1.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAK65173.1 - 9.7e-07 28.5 0.3 4.2e-06 26.4 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAK65173.1 - 0.0039 16.4 0.2 0.0082 15.3 0.2 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 GAK65173.1 - 0.0091 14.6 0.0 0.029 13.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAK65173.1 - 0.015 15.0 0.2 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAK65173.1 - 0.025 13.4 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DNA_pol_A_exo1 PF01612.15 GAK65173.1 - 0.056 12.9 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease ELO PF01151.13 GAK65174.1 - 2.9e-62 210.2 18.3 3.4e-62 210.0 12.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CoA_transf_3 PF02515.12 GAK65175.1 - 1.3e-43 148.4 0.1 2.8e-43 147.3 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III GFO_IDH_MocA PF01408.17 GAK65176.1 - 4.2e-18 66.0 0.0 6.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAK65176.1 - 1.1e-05 25.2 0.0 0.00037 20.2 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Zn_clus PF00172.13 GAK65177.1 - 0.00029 20.6 8.3 0.00029 20.6 5.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAK65178.1 - 6.8e-77 258.9 22.6 9.1e-77 258.5 15.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK65178.1 - 7.4e-20 70.9 37.3 5.6e-15 54.9 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3767 PF12597.3 GAK65178.1 - 9.5 5.9 8.6 0.31 10.7 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3767) RAI1 PF08652.6 GAK65179.1 - 2.7e-19 68.6 0.0 6.5e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Acetyltransf_1 PF00583.19 GAK65179.1 - 3.4e-06 27.0 0.0 8.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK65179.1 - 0.012 15.7 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.21 GAK65180.1 - 6.2e-20 71.0 0.0 1.4e-19 69.8 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme TFIIA PF03153.8 GAK65180.1 - 3.7 7.3 5.4 5 6.9 3.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPT PF03151.11 GAK65181.1 - 8.9e-35 119.5 6.6 8.9e-35 119.5 4.6 2.9 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 GAK65181.1 - 8.6e-14 51.1 12.4 1.3e-13 50.6 8.6 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAK65181.1 - 1e-13 51.3 22.7 1.2e-07 31.8 6.9 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 GAK65181.1 - 1e-05 24.7 11.0 0.00041 19.5 0.4 2.9 2 1 0 2 2 2 2 Nucleotide-sugar transporter Plasmod_dom_1 PF09715.5 GAK65181.1 - 0.069 13.0 1.8 3.9 7.4 0.1 2.6 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) EmrE PF13536.1 GAK65181.1 - 0.16 12.1 22.6 0.75 10.0 2.3 2.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Multi_Drug_Res PF00893.14 GAK65181.1 - 0.29 11.6 7.1 0.084 13.3 2.0 2.3 2 0 0 2 2 2 0 Small Multidrug Resistance protein Orbi_VP6 PF01516.11 GAK65182.1 - 1.1 8.1 8.3 1.5 7.7 5.7 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 MBOAT_2 PF13813.1 GAK65183.1 - 0.00083 19.3 8.7 0.0019 18.2 0.4 2.8 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family DUF1129 PF06570.6 GAK65183.1 - 0.34 10.1 6.4 1.3 8.3 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ABC_tran PF00005.22 GAK65184.1 - 4.4e-21 75.6 0.0 2.1e-15 57.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAK65184.1 - 1.2e-07 32.0 0.0 0.097 12.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 GAK65184.1 - 3.3e-05 23.7 0.0 0.025 14.4 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 GAK65184.1 - 0.0014 18.1 0.0 0.0037 16.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 GAK65184.1 - 0.013 15.2 0.0 0.036 13.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 GAK65184.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAK65184.1 - 0.017 14.5 0.2 0.089 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAK65184.1 - 0.059 13.3 3.1 0.094 12.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 GAK65184.1 - 0.06 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 GAK65184.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 GAK65184.1 - 0.21 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 F_bP_aldolase PF01116.15 GAK65185.1 - 3.4e-70 236.3 0.0 3.9e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II WD40 PF00400.27 GAK65186.1 - 2.7e-43 144.3 16.5 6.1e-10 38.5 0.1 10.5 10 0 0 10 10 10 9 WD domain, G-beta repeat eIF2A PF08662.6 GAK65186.1 - 1.5e-06 28.0 0.1 0.14 11.8 0.0 3.7 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 GAK65186.1 - 5.7e-05 22.3 0.4 0.59 9.1 0.0 3.8 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 GAK65186.1 - 0.00029 19.7 0.1 0.027 13.2 0.0 3.1 3 0 0 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 GAK65186.1 - 0.0028 15.8 1.3 0.043 11.9 0.0 3.0 3 1 0 4 4 4 1 Nucleoporin Nup120/160 DUF3312 PF11768.3 GAK65186.1 - 0.2 9.8 0.0 0.44 8.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Asp_Glu_race PF01177.17 GAK65188.1 - 8e-23 81.4 0.3 9.9e-23 81.1 0.2 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.6 GAK65188.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 AroM protein FAD_binding_4 PF01565.18 GAK65189.1 - 5e-27 94.0 1.5 5e-27 94.0 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAK65189.1 - 7.1e-13 48.2 0.1 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAK65189.1 - 0.06 12.4 0.1 0.13 11.4 0.1 1.5 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding SH3_1 PF00018.23 GAK65189.1 - 0.079 12.3 0.5 0.17 11.2 0.4 1.5 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.12 GAK65189.1 - 0.32 10.5 1.0 1.7 8.2 0.3 2.1 2 0 0 2 2 2 0 Variant SH3 domain DUF1308 PF07000.6 GAK65191.1 - 4.1e-18 65.1 0.0 1.2e-16 60.3 0.0 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) LCCL PF03815.14 GAK65191.1 - 2.3e-16 59.5 0.0 4.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 LCCL domain ADH_N PF08240.7 GAK65192.1 - 1.1e-21 76.6 2.8 2.2e-21 75.6 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK65192.1 - 2.7e-17 62.5 0.0 6.1e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAK65192.1 - 0.00029 20.0 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAK65192.1 - 0.00087 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 GAK65192.1 - 0.0011 18.3 0.1 0.0031 16.9 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 GAK65192.1 - 0.0076 16.3 0.0 0.023 14.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAK65192.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 GAK65192.1 - 0.029 14.8 0.0 2.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold AlaDh_PNT_C PF01262.16 GAK65192.1 - 0.031 13.8 0.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 GAK65192.1 - 0.12 12.1 1.5 0.15 11.8 0.3 1.7 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.11 GAK65193.1 - 7.4e-18 64.3 72.5 1.8e-12 46.6 32.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Vac14_Fig4_bd PF11916.3 GAK65193.1 - 0.17 11.0 1.0 0.28 10.3 0.7 1.2 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Acetyltransf_7 PF13508.1 GAK65194.1 - 3.4e-06 27.1 0.0 6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAK65194.1 - 7e-06 25.9 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAK65194.1 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK65194.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 GAK65194.1 - 0.043 13.6 0.1 7.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-C3HC4_2 PF13923.1 GAK65195.1 - 9.4e-07 28.7 14.6 1.9e-06 27.7 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK65195.1 - 5.9e-06 25.8 8.1 1e-05 25.0 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK65195.1 - 0.0008 19.0 12.1 0.0014 18.2 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK65195.1 - 0.0016 18.2 14.0 0.0037 17.0 9.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAK65195.1 - 0.24 11.1 10.3 0.41 10.4 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 GAK65195.1 - 0.44 10.6 10.7 1.2 9.3 7.5 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger dCMP_cyt_deam_1 PF00383.17 GAK65196.1 - 2.2e-08 33.6 0.0 5.9e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Pirin_C PF05726.8 GAK65197.1 - 3e-24 85.0 0.1 5.5e-23 81.0 0.0 2.7 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.11 GAK65197.1 - 3.1e-18 65.6 0.3 7.3e-18 64.4 0.2 1.6 1 0 0 1 1 1 1 Pirin ECR1_N PF14382.1 GAK65198.1 - 0.032 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region zf-CCHC PF00098.18 GAK65198.1 - 0.16 11.9 1.5 0.46 10.4 1.1 1.8 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 GAK65199.1 - 1.6e-22 79.8 0.0 3.3e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 GAK65199.1 - 7.3e-08 32.6 0.4 1.4e-07 31.6 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAK65199.1 - 0.0047 16.5 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Pirin PF02678.11 GAK65200.1 - 6.2e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Pirin zf-C2H2 PF00096.21 GAK65201.1 - 4.4e-07 29.8 8.1 0.00073 19.7 0.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF3493 PF11998.3 GAK65201.1 - 0.00051 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3493) zf-H2C2_2 PF13465.1 GAK65201.1 - 0.003 17.7 0.3 0.003 17.7 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAK65201.1 - 0.0041 17.3 14.8 0.042 14.1 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAK65201.1 - 0.0047 16.7 0.4 0.015 15.1 0.3 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger RR_TM4-6 PF06459.7 GAK65201.1 - 0.23 11.3 0.6 0.49 10.2 0.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 adh_short PF00106.20 GAK65202.1 - 2.7e-28 98.9 0.0 8.9e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK65202.1 - 6.5e-10 39.1 0.0 9.3e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK65202.1 - 3.3e-07 30.1 1.0 2.3e-06 27.4 0.7 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAK65202.1 - 6.7e-06 26.2 0.1 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAK65202.1 - 1.7e-05 24.3 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK65202.1 - 0.00035 19.3 0.0 0.00049 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 GAK65202.1 - 0.0027 16.8 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAK65202.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 GAK65202.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 GAK65202.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.7 GAK65205.1 - 9.3e-18 64.5 0.0 2.5e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK65205.1 - 2.5e-08 34.2 0.0 7.6e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK65205.1 - 2.7e-08 33.6 0.0 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK65205.1 - 3.5e-08 33.7 0.0 1.2e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK65205.1 - 1e-07 32.5 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK65205.1 - 2.5e-07 30.3 0.0 8.3e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK65205.1 - 6.2e-07 29.4 0.0 2.8e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK65205.1 - 9e-06 24.9 0.0 1.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAK65205.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF4210 PF13915.1 GAK65206.1 - 5.2e-21 74.7 0.0 1.3e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 GAK65206.1 - 3.1e-16 58.9 0.0 6.8e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis Ribosomal_S19e PF01090.14 GAK65207.1 - 0.079 12.3 0.5 0.16 11.4 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S19e Sulfate_transp PF00916.15 GAK65209.1 - 1.3e-76 257.3 7.1 1.3e-76 257.3 4.9 1.9 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAK65209.1 - 9.3e-32 108.5 2.4 9.3e-32 108.5 1.6 3.1 2 1 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAK65209.1 - 4.3e-10 39.0 0.0 8.5e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain VIT1 PF01988.14 GAK65210.1 - 0.0023 17.4 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 VIT family Ion_trans_2 PF07885.11 GAK65214.1 - 7.2e-32 108.9 28.4 2.7e-16 59.0 6.2 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 GAK65214.1 - 0.0086 15.3 13.1 0.15 11.3 3.1 2.6 2 1 0 2 2 2 2 Ion transport protein ADK PF00406.17 GAK65215.1 - 2e-46 157.5 0.0 2.6e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 GAK65215.1 - 1.6e-13 50.0 0.0 2.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 GAK65215.1 - 2.9e-08 34.5 0.0 6.5e-08 33.4 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 GAK65215.1 - 3e-05 23.9 0.2 0.00065 19.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAK65215.1 - 5.4e-05 23.5 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 GAK65215.1 - 0.032 13.5 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 GAK65215.1 - 0.045 12.8 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin adh_short PF00106.20 GAK65216.1 - 9.5e-29 100.4 2.7 1.2e-28 100.1 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK65216.1 - 1.8e-20 73.7 0.0 2.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK65216.1 - 2e-13 50.4 1.3 2.7e-13 49.9 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAK65216.1 - 9.8e-05 21.8 0.1 0.00015 21.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_28 PF03033.15 GAK65216.1 - 0.013 15.2 0.2 0.024 14.4 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Eno-Rase_NADH_b PF12242.3 GAK65216.1 - 0.014 15.1 0.7 0.028 14.2 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAK65216.1 - 0.1 12.6 4.3 0.71 9.8 2.9 2.2 1 1 0 1 1 1 0 NADH(P)-binding Herpes_ICP4_N PF03584.10 GAK65217.1 - 0.066 12.7 0.1 0.078 12.4 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region SR-25 PF10500.4 GAK65217.1 - 1.4 8.3 16.5 1.7 8.0 11.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SLY PF12485.3 GAK65217.1 - 4.2 7.5 15.5 5.7 7.1 10.8 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Aldo_ket_red PF00248.16 GAK65219.1 - 2e-47 161.3 0.0 2.8e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_5 PF12695.2 GAK65220.1 - 0.00098 18.8 0.7 0.0037 17.0 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK65220.1 - 0.0017 18.2 0.1 0.0036 17.1 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fe-ADH PF00465.14 GAK65221.1 - 2.1e-92 309.5 0.0 2.9e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAK65221.1 - 1.7e-12 47.2 0.0 1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DNA_ligase_A_M PF01068.16 GAK65222.1 - 0.16 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 ATP dependent DNA ligase domain MAPEG PF01124.13 GAK65223.1 - 1.8e-11 43.7 6.9 2.3e-11 43.4 4.7 1.2 1 0 0 1 1 1 1 MAPEG family HupE_UreJ_2 PF13795.1 GAK65223.1 - 0.13 11.7 1.8 1.3 8.4 0.9 2.0 1 1 1 2 2 2 0 HupE / UreJ protein AMP-binding PF00501.23 GAK65224.1 - 1.6e-70 237.6 0.3 1.9e-70 237.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK65224.1 - 1.3e-16 61.2 0.1 4.7e-16 59.5 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GPP34 PF05719.6 GAK65224.1 - 0.093 12.7 0.2 0.6 10.1 0.0 2.4 3 0 0 3 3 3 0 Golgi phosphoprotein 3 (GPP34) Lipase_GDSL_2 PF13472.1 GAK65225.1 - 8.5e-24 84.6 0.5 1e-23 84.3 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAK65225.1 - 5.7e-11 42.6 0.1 6.7e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAK65225.1 - 0.037 13.7 0.1 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family ADH_zinc_N_2 PF13602.1 GAK65225.1 - 0.075 13.9 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MS_channel PF00924.13 GAK65226.1 - 2.3e-22 79.3 1.4 4.3e-22 78.4 1.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 GAK65226.1 - 0.0028 16.8 0.3 0.0051 16.0 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAK65226.1 - 0.0092 16.1 0.7 0.028 14.5 0.4 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAK65226.1 - 0.018 14.8 0.1 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain DUF4328 PF14219.1 GAK65226.1 - 5.2 6.3 22.3 0.34 10.2 10.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4328) IQ PF00612.22 GAK65233.1 - 7.1e-05 22.1 0.3 0.00018 20.8 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Sec1 PF00995.18 GAK65233.1 - 0.013 14.1 2.3 0.02 13.5 1.6 1.2 1 0 0 1 1 1 0 Sec1 family Urm1 PF09138.6 GAK65234.1 - 5.1e-35 119.4 0.1 5.8e-35 119.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 GAK65234.1 - 2.3e-06 27.9 0.1 2.9e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 ThiS family DUF3290 PF11694.3 GAK65234.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Glyco_hydro_47 PF01532.15 GAK65235.1 - 1.2e-151 505.4 0.0 1.4e-151 505.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CHCH PF06747.8 GAK65237.1 - 0.00079 19.2 2.5 0.015 15.2 0.4 3.0 2 1 1 3 3 3 2 CHCH domain UCR_hinge PF02320.11 GAK65237.1 - 0.0079 16.1 6.9 0.014 15.2 0.5 2.6 1 1 2 3 3 3 2 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 GAK65237.1 - 0.074 12.8 8.7 0.4 10.4 1.0 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 GAK65237.1 - 0.084 12.9 6.4 0.83 9.7 0.3 2.4 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF3128 PF11326.3 GAK65237.1 - 0.19 11.8 3.7 6.4 6.9 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3128) COX17 PF05051.8 GAK65237.1 - 0.37 10.8 3.3 6.6 6.8 0.3 2.6 1 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.6 GAK65237.1 - 1.9 8.6 4.4 21 5.3 0.2 2.6 1 1 2 3 3 3 0 GCK domain DUF1903 PF08991.5 GAK65237.1 - 3.4 7.8 9.9 5.8 7.1 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1903) zf-C2HC5 PF06221.8 GAK65238.1 - 6.6e-14 51.4 2.6 1e-13 50.7 1.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DZR PF12773.2 GAK65238.1 - 0.64 9.8 4.0 1.3 8.9 2.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF902 PF06001.8 GAK65238.1 - 0.91 9.7 3.0 1.5 9.0 2.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) zf-DHHC PF01529.15 GAK65239.1 - 1.2e-28 99.6 5.7 1.3e-28 99.5 1.9 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase His_Phos_2 PF00328.17 GAK65240.1 - 2.1e-18 66.7 0.0 5.4e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aa_trans PF01490.13 GAK65241.1 - 1.1e-77 261.3 14.3 1.3e-77 260.9 9.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF754 PF05449.6 GAK65241.1 - 0.1 12.6 3.2 5.9 6.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF754) IMS PF00817.15 GAK65242.1 - 3.4e-39 134.0 0.0 1.8e-38 131.7 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 GAK65242.1 - 5.5e-15 55.4 0.0 1.5e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 GAK65242.1 - 2.5e-05 24.1 6.2 0.21 11.5 0.1 3.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 GAK65242.1 - 4e-05 23.6 0.0 8.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 GAK65242.1 - 0.035 14.1 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif DUF1805 PF08827.6 GAK65242.1 - 0.077 12.8 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Claudin_2 PF13903.1 GAK65243.1 - 0.24 11.0 15.5 0.025 14.2 3.1 3.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction IFT43 PF15305.1 GAK65244.1 - 0.0074 16.3 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport protein 43 AraC_binding_2 PF14525.1 GAK65244.1 - 0.059 12.9 0.4 0.076 12.5 0.3 1.1 1 0 0 1 1 1 0 AraC-binding-like domain PALP PF00291.20 GAK65245.1 - 1.2e-47 162.6 0.0 1e-45 156.2 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1049 PF06305.6 GAK65245.1 - 0.18 11.3 0.6 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TFR_dimer PF04253.10 GAK65246.1 - 3.5e-14 52.4 0.0 6.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 GAK65246.1 - 2.9e-13 49.9 0.1 5.1e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAK65246.1 - 5.5e-10 38.8 0.5 1.2e-09 37.8 0.4 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 GAK65246.1 - 0.0024 17.4 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 GAK65246.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Mito_carr PF00153.22 GAK65247.1 - 1.2e-56 188.3 2.0 7.1e-20 70.5 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Vac14_Fig4_bd PF11916.3 GAK65247.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Bac_luciferase PF00296.15 GAK65248.1 - 7.5e-66 222.3 4.0 1e-65 221.9 2.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Trehalase PF01204.13 GAK65251.1 - 4.3e-116 388.5 1.9 6.3e-105 351.7 0.0 2.2 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 GAK65251.1 - 6.3e-05 21.8 0.3 0.0011 17.7 0.0 2.1 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase DFF-C PF09033.5 GAK65251.1 - 0.043 13.6 0.7 0.088 12.6 0.0 1.8 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain DUF566 PF04484.7 GAK65251.1 - 5.2 6.4 11.4 9.4 5.6 7.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) PNK3P PF08645.6 GAK65252.1 - 2.1e-45 154.0 0.0 3.1e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 GAK65252.1 - 2.9e-30 105.0 1.8 4.8e-30 104.3 0.2 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAK65252.1 - 4.9e-06 25.7 0.2 0.075 12.1 0.0 2.6 3 0 0 3 3 3 2 Zeta toxin KTI12 PF08433.5 GAK65252.1 - 0.019 14.2 1.5 0.64 9.1 1.0 2.1 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 GAK65252.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAK65252.1 - 0.058 14.2 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAK65252.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain G_glu_transpept PF01019.16 GAK65253.1 - 2e-146 488.5 0.6 2.2e-146 488.3 0.4 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ACOX PF01756.14 GAK65254.1 - 5.3e-39 133.5 0.4 1e-38 132.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 GAK65254.1 - 1.5e-23 83.4 0.1 2.9e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 GAK65254.1 - 9.8e-12 44.2 0.4 2.8e-11 42.7 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAK65254.1 - 0.00025 21.1 0.5 0.018 15.1 0.3 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.13 GAK65255.1 - 3.9e-06 26.6 11.0 6.7e-06 25.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.8 GAK65256.1 - 4.6e-15 55.4 1.4 8.3e-15 54.6 0.9 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 AMP-binding PF00501.23 GAK65256.1 - 4.4e-07 28.6 0.0 7.7e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PAN_4 PF14295.1 GAK65257.1 - 0.00028 20.5 0.4 0.00068 19.2 0.3 1.7 1 0 0 1 1 1 1 PAN domain Methyltransf_12 PF08242.7 GAK65258.1 - 1.9e-06 28.2 0.0 4.5e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK65258.1 - 3.3e-06 26.9 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK65258.1 - 8.5e-06 26.3 0.0 1.8e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK65258.1 - 5.2e-05 23.6 0.0 0.00044 20.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.12 GAK65258.1 - 0.027 13.8 0.0 0.056 12.8 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.1 GAK65258.1 - 0.062 12.8 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAK65258.1 - 0.08 12.9 0.2 0.68 9.9 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 GAK65258.1 - 0.097 13.5 0.1 0.2 12.5 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Lin0512_fam PF09585.5 GAK65258.1 - 0.16 11.5 0.1 0.65 9.5 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Sugar_tr PF00083.19 GAK65259.1 - 1.3e-106 356.8 17.3 1.7e-106 356.5 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK65259.1 - 1.3e-18 66.8 40.0 1.1e-15 57.2 13.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AgrB PF04647.10 GAK65259.1 - 0.045 12.8 0.1 0.045 12.8 0.0 3.0 3 0 0 3 3 3 0 Accessory gene regulator B YqhR PF11085.3 GAK65259.1 - 0.077 12.5 0.0 0.077 12.5 0.0 2.7 3 0 0 3 3 3 0 Conserved membrane protein YqhR Pox_A14 PF05767.7 GAK65259.1 - 0.48 10.4 0.0 0.48 10.4 0.0 3.1 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Zn_clus PF00172.13 GAK65260.1 - 0.029 14.2 8.3 0.15 12.0 5.8 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rsa3 PF14615.1 GAK65261.1 - 0.097 11.9 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Phage_integrase PF00589.17 GAK65262.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family R3H-assoc PF13902.1 GAK65262.1 - 0.11 12.5 3.6 0.41 10.6 0.1 2.6 2 0 0 2 2 2 0 R3H-associated N-terminal domain DUF1661 PF07877.6 GAK65264.1 - 0.018 14.5 0.8 0.047 13.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Vsr PF03852.10 GAK65264.1 - 0.13 11.9 0.4 0.28 10.8 0.3 1.5 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Glyco_hydro_42 PF02449.10 GAK65265.1 - 1.3e-116 389.8 4.8 1.7e-116 389.4 3.3 1.2 1 0 0 1 1 1 1 Beta-galactosidase Na_H_Exchanger PF00999.16 GAK65265.1 - 3.5e-40 137.6 17.2 4.9e-40 137.2 12.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_42M PF08532.5 GAK65265.1 - 5.5e-34 117.1 0.0 9.3e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42C PF08533.5 GAK65265.1 - 0.00098 18.5 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Cellulase PF00150.13 GAK65265.1 - 0.015 14.5 0.2 0.027 13.6 0.2 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) GRASP55_65 PF04495.9 GAK65266.1 - 4.4e-07 29.9 0.0 7.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 GAK65266.1 - 6.9e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 GAK65266.1 - 0.0009 19.3 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Abhydrolase_6 PF12697.2 GAK65267.1 - 8.6e-13 48.6 0.1 3.3e-12 46.7 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK65267.1 - 0.00064 19.5 0.0 0.0041 16.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK65267.1 - 0.019 14.5 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Nop25 PF09805.4 GAK65269.1 - 0.0025 17.8 6.6 0.0048 16.9 4.6 1.4 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) Bap31 PF05529.7 GAK65269.1 - 2.1 7.7 9.4 3.5 7.0 6.5 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Chromate_transp PF02417.10 GAK65270.1 - 8.9e-52 175.0 24.9 1.1e-27 96.6 4.9 3.8 4 1 0 4 4 4 2 Chromate transporter DUF2635 PF10948.3 GAK65271.1 - 0.063 12.5 0.1 0.31 10.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) Acetyltransf_3 PF13302.1 GAK65272.1 - 2.9e-09 37.2 0.0 3.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAK65272.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAK65272.1 - 0.00058 19.9 0.1 0.0009 19.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAK65272.1 - 0.00069 19.5 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK65272.1 - 0.00069 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 GAK65272.1 - 0.0015 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAK65272.1 - 0.017 14.7 0.1 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAK65272.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HPP PF04982.8 GAK65273.1 - 5.1e-38 129.5 4.9 7.8e-38 129.0 3.4 1.3 1 0 0 1 1 1 1 HPP family DUF202 PF02656.10 GAK65273.1 - 9.1 6.5 11.5 29 4.9 2.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) p450 PF00067.17 GAK65275.1 - 6e-68 229.4 0.0 8.4e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COX4 PF02936.9 GAK65276.1 - 0.085 12.5 1.6 0.47 10.1 0.0 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV bZIP_1 PF00170.16 GAK65277.1 - 3.4e-10 39.7 13.5 6.1e-07 29.2 3.6 2.3 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 GAK65277.1 - 6.2e-08 32.2 3.7 1.9e-07 30.7 2.5 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 GAK65277.1 - 1.4 8.7 15.5 0.14 11.9 2.1 2.8 3 0 0 3 3 3 0 Basic region leucine zipper SCF PF02404.10 GAK65278.1 - 0.38 9.9 2.9 0.27 10.4 0.6 1.6 1 1 1 2 2 2 0 Stem cell factor Peptidase_S64 PF08192.6 GAK65278.1 - 4.1 5.6 10.9 5.1 5.3 7.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 NAD_binding_2 PF03446.10 GAK65279.1 - 1.2e-34 119.4 0.3 1.8e-34 118.9 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAK65279.1 - 8.2e-30 103.3 0.0 1.9e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAK65279.1 - 0.028 14.8 0.5 0.2 12.1 0.1 2.3 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ribonuclease_3 PF00636.21 GAK65280.1 - 4.9e-15 55.9 0.0 1.3e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAK65280.1 - 0.021 14.7 0.1 0.22 11.4 0.1 2.3 1 1 0 1 1 1 0 Ribonuclease-III-like DUF3891 PF13030.1 GAK65280.1 - 0.039 13.4 1.4 0.048 13.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3891) DUF1839 PF08893.5 GAK65280.1 - 0.058 12.3 0.1 0.18 10.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1839) TTKRSYEDQ PF10212.4 GAK65280.1 - 0.19 10.5 1.8 0.28 10.0 1.3 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Pro_isomerase PF00160.16 GAK65282.1 - 5.2e-41 140.4 0.0 6e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DnaJ_CXXCXGXG PF00684.14 GAK65283.1 - 0.42 10.7 7.1 0.59 10.2 0.7 2.5 2 0 0 2 2 2 0 DnaJ central domain RCR PF12273.3 GAK65284.1 - 0.13 12.7 3.0 0.36 11.3 2.0 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF1669 PF07894.7 GAK65284.1 - 0.16 11.1 0.4 0.24 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) PBP1_TM PF14812.1 GAK65284.1 - 2.2 8.6 4.9 1.9 8.8 1.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallophos PF00149.23 GAK65285.1 - 8.3e-24 84.0 0.2 1.2e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAK65285.1 - 9.7e-16 57.6 0.1 2.3e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAK65285.1 - 1.7e-08 33.4 1.1 2.7e-08 32.8 0.8 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAK65285.1 - 0.00081 19.2 0.1 0.0025 17.6 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MRF_C2 PF13888.1 GAK65285.1 - 0.019 14.7 0.6 0.044 13.5 0.4 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 fn3 PF00041.16 GAK65285.1 - 0.35 11.0 4.7 1.7 8.8 1.5 2.6 2 1 0 2 2 2 0 Fibronectin type III domain AATF-Che1 PF13339.1 GAK65286.1 - 0.0044 17.1 5.3 0.02 15.0 2.7 2.5 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Prefoldin PF02996.12 GAK65288.1 - 9.7e-11 41.3 0.2 1.7e-10 40.6 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit FliD_N PF02465.13 GAK65288.1 - 0.017 15.4 2.0 0.052 13.9 0.1 2.3 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ATG16 PF08614.6 GAK65288.1 - 0.021 14.6 2.6 0.038 13.7 1.8 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 GAK65288.1 - 0.089 12.9 0.7 6.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MiaE PF06175.6 GAK65288.1 - 0.12 11.6 0.9 0.16 11.3 0.6 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) CCD PF07860.6 GAK65288.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 1 0 1 1 1 0 WisP family C-Terminal Region TFIID_90kDa PF04494.10 GAK65288.1 - 0.13 12.2 1.1 0.21 11.6 0.1 1.8 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit MerR-DNA-bind PF09278.6 GAK65288.1 - 4.8 7.6 7.3 10 6.5 0.5 2.9 2 1 1 3 3 3 0 MerR, DNA binding Complex1_LYR PF05347.10 GAK65289.1 - 1.6e-09 37.4 0.2 2.9e-09 36.5 0.0 1.6 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAK65289.1 - 4.3e-07 30.0 0.7 6.7e-07 29.4 0.0 1.7 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 GAK65289.1 - 0.00045 20.6 0.3 0.00064 20.1 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like adh_short PF00106.20 GAK65290.1 - 7.4e-20 71.5 0.3 1.6e-19 70.4 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK65290.1 - 2.3e-18 66.8 0.0 3.5e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK65290.1 - 7.8e-05 22.4 0.1 0.00013 21.6 0.0 1.4 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 GAK65290.1 - 0.014 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AA_kinase PF00696.23 GAK65290.1 - 0.067 12.7 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family Cofilin_ADF PF00241.15 GAK65291.1 - 8.1e-16 58.0 0.0 2.2e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF2985 PF11204.3 GAK65292.1 - 9.7e-26 89.3 0.9 9.7e-26 89.3 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) TraY PF05509.6 GAK65293.1 - 7.4 6.4 7.2 1 9.2 1.8 1.9 2 0 0 2 2 2 0 TraY domain Asp PF00026.18 GAK65294.1 - 6.8e-55 186.5 12.0 1.5e-54 185.4 8.3 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAK65294.1 - 2e-06 27.8 4.0 2e-06 27.8 2.7 3.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAK65294.1 - 0.00015 22.1 0.7 0.014 15.9 0.1 2.9 2 0 0 2 2 2 1 Aspartyl protease PseudoU_synth_2 PF00849.17 GAK65295.1 - 5.3e-26 91.4 0.0 1.1e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase Methyltransf_26 PF13659.1 GAK65295.1 - 3.1e-15 56.2 0.1 9.8e-15 54.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 GAK65295.1 - 4.4e-14 52.4 0.0 9.3e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 GAK65295.1 - 2.3e-05 24.0 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.3 GAK65295.1 - 0.00083 18.4 0.0 0.21 10.5 0.0 2.4 1 1 1 2 2 2 2 RRNA methyltransferase AviRa Methyltransf_18 PF12847.2 GAK65295.1 - 0.025 15.1 0.0 0.064 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 GAK65295.1 - 0.068 12.8 0.0 0.26 10.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.10 GAK65296.1 - 3.2e-12 46.0 0.1 6.7e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAK65296.1 - 6.7e-10 39.0 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 GAK65296.1 - 2e-06 28.2 0.8 4.3e-06 27.1 0.1 1.8 1 1 1 2 2 2 1 Complex1_LYR-like His_Phos_2 PF00328.17 GAK65297.1 - 7.8e-24 84.6 0.0 2.8e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Hexokinase_2 PF03727.11 GAK65298.1 - 8e-74 247.9 0.2 1.1e-73 247.4 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAK65298.1 - 6.3e-68 228.1 0.0 9.5e-68 227.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Epimerase PF01370.16 GAK65299.1 - 1e-22 80.7 0.0 1.6e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK65299.1 - 2.8e-12 45.9 0.0 1.4e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAK65299.1 - 4.3e-10 38.9 0.1 3.3e-09 36.0 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAK65299.1 - 5.4e-08 33.0 0.0 1.6e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAK65299.1 - 1.4e-07 30.6 0.0 3.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 GAK65299.1 - 0.0012 18.7 0.1 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 GAK65299.1 - 0.0031 16.5 0.1 0.0043 16.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 GAK65299.1 - 0.014 14.6 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 GAK65299.1 - 0.04 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 GAK65299.1 - 0.087 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 GAK65299.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RTA1 PF04479.8 GAK65300.1 - 2.9e-48 164.3 0.3 4e-48 163.8 0.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Rubis-subs-bind PF09273.6 GAK65301.1 - 0.0018 18.1 0.4 0.044 13.6 0.3 2.4 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 GAK65301.1 - 0.022 15.0 0.0 0.42 10.9 0.0 2.6 1 1 0 1 1 1 0 SET domain MIP PF00230.15 GAK65302.1 - 4.6e-22 78.6 9.5 6.8e-22 78.0 6.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Rod-binding PF10135.4 GAK65302.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Rod binding protein Pkinase PF00069.20 GAK65304.1 - 4e-39 134.3 0.0 2e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK65304.1 - 2.3e-15 56.3 0.0 4.8e-11 42.2 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK65304.1 - 5.1e-05 22.3 0.0 0.021 13.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAK65304.1 - 0.034 13.8 0.0 0.28 10.8 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 GAK65305.1 - 3e-22 79.2 0.7 1.8e-20 73.4 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK65305.1 - 3e-12 46.5 0.0 5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK65305.1 - 3.6e-12 46.6 0.2 4.7e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK65305.1 - 2e-08 33.7 0.2 1.8e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 GAK65305.1 - 0.00041 19.2 0.0 0.0014 17.4 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 GAK65305.1 - 0.0012 18.3 0.0 0.066 12.6 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIP PF03583.9 GAK65305.1 - 0.0055 15.9 0.0 0.0099 15.1 0.0 1.4 1 0 0 1 1 1 1 Secretory lipase Esterase_phd PF10503.4 GAK65305.1 - 0.0089 15.2 0.0 0.62 9.2 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.2 GAK65305.1 - 0.031 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF202 PF02656.10 GAK65306.1 - 9.8e-05 22.4 1.5 0.0021 18.2 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF202) RCC1 PF00415.13 GAK65308.1 - 9.1e-13 48.2 21.2 0.0075 16.4 0.0 8.3 7 5 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAK65308.1 - 5.2e-07 29.1 31.0 0.00051 19.5 0.5 7.2 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Sigma70_r4_2 PF08281.7 GAK65308.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Pyr_redox_2 PF07992.9 GAK65309.1 - 7.8e-25 87.9 0.0 6.5e-16 58.8 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK65309.1 - 1.1e-12 48.1 0.0 1e-11 45.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK65309.1 - 0.00094 19.3 0.1 0.06 13.3 0.0 3.2 3 2 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAK65309.1 - 0.072 13.3 0.1 2.4 8.4 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding TPPII_N PF12583.3 GAK65309.1 - 0.087 12.9 0.3 0.35 10.9 0.0 2.1 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal Acetyltransf_3 PF13302.1 GAK65311.1 - 3.5e-21 75.8 0.0 4.5e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAK65311.1 - 4.4e-10 39.7 0.0 5.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAK65311.1 - 0.005 16.8 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AstA PF04958.7 GAK65311.1 - 0.043 12.2 0.0 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit C2 PF00168.25 GAK65312.1 - 1.2e-18 66.7 0.0 6.7e-14 51.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain zf-TRAF PF02176.13 GAK65314.1 - 5.5e-09 36.2 14.9 3.9e-07 30.3 1.0 5.3 3 1 3 7 7 6 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 GAK65314.1 - 2.8e-07 30.4 8.7 2.8e-07 30.4 6.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK65314.1 - 4.2e-07 29.6 10.4 4.2e-07 29.6 7.2 3.2 2 1 1 3 3 1 1 Ring finger domain zf-RING_5 PF14634.1 GAK65314.1 - 5.9e-06 25.9 9.3 5.9e-06 25.9 6.4 3.0 3 1 0 3 3 1 1 zinc-RING finger domain zf-Nse PF11789.3 GAK65314.1 - 0.0004 19.8 4.2 0.0004 19.8 2.9 2.7 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 GAK65314.1 - 0.00046 19.7 8.9 0.00046 19.7 6.2 3.9 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAK65314.1 - 0.0018 17.9 7.0 0.0018 17.9 4.8 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAK65314.1 - 0.0046 16.6 3.9 0.0046 16.6 2.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger BMFP PF04380.8 GAK65314.1 - 0.21 11.7 0.9 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Membrane fusogenic activity zf-RING_6 PF14835.1 GAK65314.1 - 1.5 8.6 7.7 0.16 11.7 1.6 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Sina PF03145.11 GAK65314.1 - 3.8 7.1 20.3 0.54 9.8 2.0 3.9 1 1 3 4 4 4 0 Seven in absentia protein family Aa_trans PF01490.13 GAK65315.1 - 4.9e-61 206.4 11.6 6e-61 206.1 8.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 GAK65315.1 - 0.00014 20.7 9.5 0.00014 20.7 6.6 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Herpes_pp85 PF04637.7 GAK65315.1 - 0.28 9.4 1.4 0.59 8.3 0.9 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Peptidase_M20 PF01546.23 GAK65316.1 - 3.5e-33 114.6 0.0 7e-33 113.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAK65316.1 - 7.8e-12 44.9 0.0 2.7e-11 43.1 0.0 1.9 2 1 0 2 2 2 1 Peptidase dimerisation domain Sedlin_N PF04628.8 GAK65317.1 - 5.9e-34 116.7 0.0 7.1e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_7 PF03441.9 GAK65318.1 - 4.8e-88 294.9 0.0 6.3e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAK65318.1 - 7e-39 133.2 0.1 1.3e-38 132.3 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase MMgT PF10270.4 GAK65319.1 - 3.8e-24 85.1 0.2 4.2e-24 85.0 0.1 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter AA_permease_2 PF13520.1 GAK65320.1 - 1.6e-55 188.3 55.8 2e-55 188.0 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAK65320.1 - 8.5e-33 113.3 50.2 1.1e-32 113.0 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4342 PF14242.1 GAK65320.1 - 0.24 11.1 1.5 5 6.9 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF2614 PF11023.3 GAK65320.1 - 4.2 7.1 6.5 6.6 6.5 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2614) 4HBT PF03061.17 GAK65321.1 - 1.5e-17 63.4 8.4 7.5e-10 38.8 0.1 3.0 3 0 0 3 3 3 2 Thioesterase superfamily ABC_tran PF00005.22 GAK65322.1 - 1.5e-43 148.3 0.4 2.8e-22 79.4 0.0 4.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 GAK65322.1 - 8.2e-16 58.7 1.0 1.5e-05 25.1 0.0 3.9 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 GAK65322.1 - 1.2e-11 44.2 0.0 0.00015 21.0 0.0 3.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAK65322.1 - 5.5e-10 38.6 0.3 0.00034 20.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 GAK65322.1 - 6.2e-08 32.8 2.6 0.0015 18.5 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 GAK65322.1 - 9e-08 32.6 7.6 0.00055 20.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAK65322.1 - 7.5e-07 28.4 0.7 0.0054 15.9 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAK65322.1 - 2.1e-06 27.6 1.1 0.0044 16.9 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 GAK65322.1 - 2.3e-06 27.3 0.0 0.03 13.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 GAK65322.1 - 1.4e-05 25.2 0.0 0.057 13.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 GAK65322.1 - 1.7e-05 24.4 6.2 0.00045 19.8 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 GAK65322.1 - 3.5e-05 24.6 4.7 0.029 15.2 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 GAK65322.1 - 3.9e-05 23.1 0.9 0.28 10.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 GAK65322.1 - 6.6e-05 23.1 0.0 0.48 10.6 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 GAK65322.1 - 0.00011 21.9 0.4 0.057 13.1 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 GAK65322.1 - 0.00014 22.3 0.0 0.071 13.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein ABC_tran_2 PF12848.2 GAK65322.1 - 0.00024 20.8 5.7 0.00024 20.8 3.9 2.2 2 0 0 2 2 1 1 ABC transporter AAA_28 PF13521.1 GAK65322.1 - 0.00028 20.8 0.6 0.087 12.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAK65322.1 - 0.00061 18.9 4.5 0.64 8.9 0.0 3.9 5 0 0 5 5 4 2 AAA ATPase domain Dynamin_N PF00350.18 GAK65322.1 - 0.00077 19.3 0.1 0.19 11.5 0.0 2.9 2 0 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 GAK65322.1 - 0.0015 18.2 0.5 0.35 10.5 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 GAK65322.1 - 0.0019 18.1 0.0 1.3 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 GAK65322.1 - 0.0019 18.0 0.1 0.02 14.8 0.0 2.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 GAK65322.1 - 0.0037 16.9 1.7 4.8 6.8 0.1 3.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAK65322.1 - 0.0041 17.2 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.17 GAK65322.1 - 0.0087 14.9 0.1 2.5 6.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 GAK65322.1 - 0.014 15.2 4.5 0.85 9.4 0.0 3.4 3 1 0 3 3 3 0 AAA domain ATP-grasp_3 PF02655.9 GAK65322.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain SRP54 PF00448.17 GAK65322.1 - 0.017 14.6 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 GAK65322.1 - 0.017 14.5 1.7 4.3 6.7 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.4 GAK65322.1 - 0.027 13.0 7.8 0.075 11.5 0.0 3.4 4 0 0 4 4 4 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 GAK65322.1 - 0.031 13.9 3.0 1.2 8.8 0.1 2.8 3 0 0 3 3 2 0 NTPase AAA_10 PF12846.2 GAK65322.1 - 0.045 13.1 2.8 1.5 8.1 0.1 3.3 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 GAK65322.1 - 0.06 12.8 4.8 0.36 10.2 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 GAK65322.1 - 0.061 12.7 1.0 0.27 10.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 GAK65322.1 - 0.12 11.7 2.2 1.5 8.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 GAK65322.1 - 0.13 11.7 1.8 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 GAK65322.1 - 0.2 10.3 8.8 2.7 6.6 0.1 3.7 4 0 0 4 4 4 0 ArgK protein AAA_18 PF13238.1 GAK65322.1 - 0.42 10.9 9.5 0.32 11.3 1.4 3.2 3 1 0 3 3 2 0 AAA domain Med3 PF11593.3 GAK65322.1 - 0.54 9.4 8.4 1 8.5 5.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F-box-like PF12937.2 GAK65323.1 - 3.6e-10 39.3 0.1 1e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK65323.1 - 8.5e-08 31.6 0.0 2.2e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 GAK65323.1 - 4.8e-06 26.1 1.4 0.00064 19.3 0.7 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 GAK65323.1 - 0.00014 21.4 2.3 0.017 14.9 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAK65323.1 - 0.0013 18.2 1.7 0.0081 15.7 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAK65323.1 - 0.0023 17.7 3.5 0.0026 17.5 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAK65323.1 - 0.0055 16.4 0.2 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAK65323.1 - 0.0071 16.6 0.1 0.033 14.5 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAK65323.1 - 0.063 13.9 0.4 0.063 13.9 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAK65323.1 - 0.11 12.8 0.0 0.51 10.6 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAK65323.1 - 0.12 12.3 5.5 0.088 12.7 1.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat ADH_N PF08240.7 GAK65324.1 - 2.3e-26 91.6 2.5 2.3e-26 91.6 1.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK65324.1 - 1.1e-22 80.0 0.1 1.7e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 GAK65324.1 - 0.037 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 GAK65324.1 - 0.038 14.8 0.0 0.088 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 GAK65325.1 - 9.5e-24 84.5 0.0 4.7e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAK65325.1 - 7e-19 67.4 0.0 4.2e-18 64.8 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAK65325.1 - 8.3e-16 58.4 0.1 1.9e-09 37.6 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK65325.1 - 1.1e-10 41.3 2.7 6.1e-09 35.7 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK65325.1 - 1.3e-10 40.6 0.7 3.7e-09 35.9 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAK65325.1 - 1.1e-08 35.4 1.9 0.00098 19.4 0.2 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK65325.1 - 5.5e-07 29.4 5.7 9.9e-05 22.1 0.1 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAK65325.1 - 9e-07 28.1 0.2 0.0013 17.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 GAK65325.1 - 0.00011 22.3 0.0 0.63 10.1 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAK65325.1 - 0.00013 22.1 0.0 0.093 13.0 0.0 2.5 3 0 0 3 3 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 GAK65325.1 - 0.00018 20.6 1.3 0.046 12.7 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.13 GAK65325.1 - 0.00035 20.2 1.6 0.00055 19.6 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 GAK65325.1 - 0.0006 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 GAK65325.1 - 0.00098 18.7 0.8 0.65 9.5 0.1 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 GAK65325.1 - 0.0057 15.1 4.1 0.07 11.5 0.6 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAK65325.1 - 0.0066 15.5 1.2 0.17 10.9 0.1 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 GAK65325.1 - 0.014 14.2 0.4 0.014 14.2 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 GAK65325.1 - 0.044 12.8 0.1 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 GAK65325.1 - 0.045 12.6 4.2 0.83 8.4 0.2 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 GAK65325.1 - 0.063 12.6 0.6 0.13 11.6 0.4 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 GAK65325.1 - 0.068 13.1 1.2 3 7.8 0.2 2.3 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_2 PF03446.10 GAK65325.1 - 0.11 12.2 0.2 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 GAK65325.1 - 0.8 9.5 3.3 7.4 6.4 0.2 2.3 2 0 0 2 2 2 0 ThiF family AA_permease_2 PF13520.1 GAK65326.1 - 1.4e-67 228.1 53.2 1.7e-67 227.8 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAK65326.1 - 1.1e-08 33.8 50.8 4.1e-08 32.0 35.2 1.7 1 1 0 1 1 1 1 Amino acid permease Methyltransf_26 PF13659.1 GAK65327.1 - 4.3e-09 36.4 0.0 1e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 GAK65327.1 - 2.5e-08 33.7 0.0 0.00022 20.8 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 GAK65327.1 - 0.11 11.5 0.0 0.62 9.0 0.0 1.8 2 0 0 2 2 2 0 N-6 DNA Methylase Acetyltransf_1 PF00583.19 GAK65328.1 - 7.1e-06 25.9 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAK65328.1 - 0.0027 17.8 0.1 0.0061 16.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAK65328.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 GAK65329.1 - 2.4e-20 72.4 2.2 4.1e-20 71.6 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAK65329.1 - 0.0039 17.0 0.0 0.0097 15.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.4 GAK65330.1 - 1.8e-18 66.7 0.0 6.1e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.7 GAK65330.1 - 0.061 12.6 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region M_domain PF12938.2 GAK65331.1 - 0.052 13.3 2.2 0.12 12.1 1.5 1.6 1 0 0 1 1 1 0 M domain of GW182 S_tail_recep_bd PF14928.1 GAK65334.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain His_Phos_1 PF00300.17 GAK65336.1 - 2.1e-27 96.1 0.1 4.7e-27 95.0 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Peptidase_M50B PF13398.1 GAK65337.1 - 1.3e-59 200.9 15.3 1.7e-59 200.5 10.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Phage_holin_5 PF06946.6 GAK65338.1 - 0.037 14.1 0.1 0.09 12.9 0.1 1.7 1 0 0 1 1 1 0 Phage holin UPF0029 PF01205.14 GAK65339.1 - 4e-28 97.2 0.0 8.8e-28 96.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 GAK65339.1 - 1.3e-06 28.2 0.0 4.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 RWD domain Inhibitor_I9 PF05922.11 GAK65340.1 - 4.3e-08 33.6 0.1 1.1e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 Thioredoxin PF00085.15 GAK65341.1 - 0.043 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin PRCC PF10253.4 GAK65341.1 - 0.15 12.7 1.6 0.2 12.3 1.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting OCC1 PF15506.1 GAK65341.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 OCC1 family Cwf_Cwc_15 PF04889.7 GAK65341.1 - 5.2 6.7 10.8 1.3 8.7 5.4 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rhomboid PF01694.17 GAK65342.1 - 6e-21 74.9 4.5 6e-21 74.9 3.2 1.8 3 0 0 3 3 3 1 Rhomboid family DUF155 PF02582.9 GAK65343.1 - 4.8e-52 176.3 0.1 7.2e-52 175.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 VirionAssem_T7 PF11653.3 GAK65343.1 - 6.4 7.6 7.0 0.64 10.8 0.4 2.5 2 1 0 2 2 2 0 Bacteriophage T7 virion assembly protein Pyridoxal_deC PF00282.14 GAK65344.1 - 1.9e-64 217.4 0.0 2.4e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 GAK65344.1 - 5.4e-06 25.7 0.0 2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAK65344.1 - 0.00018 20.4 0.0 0.0014 17.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Methyltransf_31 PF13847.1 GAK65345.1 - 5.2e-19 68.3 0.0 9.5e-19 67.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK65345.1 - 8.7e-17 61.4 0.0 5e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK65345.1 - 4.4e-15 55.9 0.0 1.7e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK65345.1 - 5.7e-14 52.6 0.0 2.4e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK65345.1 - 7.9e-14 51.6 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK65345.1 - 9.1e-12 44.6 0.0 1.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 GAK65345.1 - 2.5e-11 43.1 0.0 8.2e-11 41.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAK65345.1 - 8.7e-10 38.8 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK65345.1 - 2.1e-08 34.2 0.1 4.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAK65345.1 - 6.9e-08 32.2 0.0 9.3e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 GAK65345.1 - 2.3e-06 26.8 0.0 3.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 GAK65345.1 - 5.6e-06 26.0 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAK65345.1 - 0.00021 20.4 0.0 0.00031 19.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 GAK65345.1 - 0.00073 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 GAK65345.1 - 0.00074 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 GCD14 PF08704.5 GAK65345.1 - 0.0012 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.8 GAK65345.1 - 0.0055 16.0 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 RrnaAD PF00398.15 GAK65345.1 - 0.0075 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 GAK65345.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 GAK65345.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.9 GAK65345.1 - 0.049 12.8 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 GAK65345.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase N6_Mtase PF02384.11 GAK65345.1 - 0.12 11.3 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Fibrillarin PF01269.12 GAK65345.1 - 0.13 11.1 0.1 0.52 9.1 0.0 1.9 2 0 0 2 2 2 0 Fibrillarin DEAD PF00270.24 GAK65346.1 - 2.5e-22 79.1 0.0 4.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 GAK65346.1 - 1.1e-12 48.3 1.3 5.1e-12 46.1 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 GAK65346.1 - 7.2e-12 45.0 0.0 2.2e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 GAK65346.1 - 4e-06 26.8 0.0 7.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like G10 PF01125.12 GAK65347.1 - 5.3e-30 103.8 0.4 5.8e-30 103.7 0.3 1.0 1 0 0 1 1 1 1 G10 protein Pkinase PF00069.20 GAK65348.1 - 2.2e-67 226.9 0.0 3.1e-58 196.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK65348.1 - 3.8e-32 111.3 0.0 2.6e-26 92.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK65348.1 - 0.0004 19.4 0.9 2 7.2 0.0 3.4 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.17 GAK65348.1 - 0.034 13.5 2.1 0.19 11.0 0.1 2.2 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 GAK65348.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase G_glu_transpept PF01019.16 GAK65349.1 - 4.2e-136 454.4 2.3 1.8e-134 449.0 1.6 2.0 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase GST_N_3 PF13417.1 GAK65351.1 - 5.1e-05 23.4 0.0 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK65351.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAK65351.1 - 0.093 12.7 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Uricase PF01014.13 GAK65352.1 - 0.0015 18.5 0.0 0.0039 17.2 0.0 1.7 2 0 0 2 2 2 1 Uricase Lipase_3 PF01764.20 GAK65353.1 - 5.9e-17 61.5 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) MR_MLE_C PF13378.1 GAK65354.1 - 6.3e-14 51.8 0.1 1.6e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAK65354.1 - 3.7e-12 46.6 0.1 1.1e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAK65354.1 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 GAK65354.1 - 0.0067 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Abhydrolase_3 PF07859.8 GAK65355.1 - 1e-10 41.5 0.1 5.2e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK65355.1 - 1.8e-10 40.7 0.0 2.8e-10 40.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK65355.1 - 5.9e-09 36.1 2.5 8.3e-09 35.6 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK65355.1 - 1.1e-05 24.7 0.1 0.00026 20.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.9 GAK65355.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase COesterase PF00135.23 GAK65355.1 - 0.19 10.3 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family LysM PF01476.15 GAK65356.1 - 2.7e-15 55.9 0.2 1.7e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 LysM domain RF-1 PF00472.15 GAK65358.1 - 2.5e-37 127.1 2.2 5.1e-37 126.1 1.5 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 GAK65358.1 - 3.6e-32 110.5 0.2 8.7e-32 109.2 0.1 1.7 1 0 0 1 1 1 1 PCRF domain Tail_P2_I PF09684.5 GAK65358.1 - 0.048 13.2 0.2 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) DUF3095 PF11294.3 GAK65358.1 - 0.05 12.6 0.9 0.21 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3095) HLH PF00010.21 GAK65359.1 - 3.2e-07 29.9 1.7 3.2e-07 29.9 1.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4098 PF13345.1 GAK65360.1 - 0.0063 16.4 0.4 3.8 7.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4098) CfAFP PF05264.6 GAK65361.1 - 0.082 12.6 0.5 0.19 11.4 0.4 1.5 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) Siva PF05458.7 GAK65361.1 - 0.26 10.8 3.9 0.48 9.9 2.7 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) ECH PF00378.15 GAK65363.1 - 2.4e-41 141.4 0.9 6.1e-40 136.8 0.6 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PS_Dcarbxylase PF02666.10 GAK65364.1 - 1.7e-76 256.0 0.0 4.1e-58 196.0 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase Pmp3 PF01679.12 GAK65364.1 - 2.4e-19 68.7 8.7 4e-19 68.0 6.0 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Nnf1 PF03980.9 GAK65365.1 - 1.9e-10 40.6 7.5 1.9e-10 40.6 5.2 2.3 2 1 0 2 2 2 1 Nnf1 Filament PF00038.16 GAK65365.1 - 0.0017 17.8 8.1 0.0017 17.8 5.6 1.9 2 1 0 2 2 2 1 Intermediate filament protein DUF2968 PF11180.3 GAK65365.1 - 0.0067 15.8 12.4 0.0067 15.8 8.6 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) Snapin_Pallidin PF14712.1 GAK65365.1 - 0.024 14.9 8.6 0.76 10.1 0.6 3.5 3 0 0 3 3 3 0 Snapin/Pallidin DUF342 PF03961.8 GAK65365.1 - 0.028 12.8 1.8 0.04 12.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Striatin PF08232.7 GAK65365.1 - 0.03 14.6 3.1 0.03 14.6 2.1 3.3 3 1 0 3 3 3 0 Striatin family Dynein_heavy PF03028.10 GAK65365.1 - 0.089 10.8 3.3 0.15 10.0 2.3 1.4 1 1 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor Laminin_II PF06009.7 GAK65365.1 - 0.097 12.4 6.3 0.11 12.1 3.0 2.2 2 0 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.7 GAK65365.1 - 0.22 11.3 6.4 0.23 11.2 3.1 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 GAK65365.1 - 0.26 9.1 5.5 0.38 8.5 3.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 GAK65365.1 - 0.39 10.8 17.6 0.12 12.5 5.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF948 PF06103.6 GAK65365.1 - 1.4 8.7 5.7 0.59 10.0 1.2 2.4 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 GAK65365.1 - 2.5 6.9 7.9 4.8 6.0 5.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 GAK65365.1 - 3.1 7.8 8.7 0.19 11.8 1.7 2.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 GAK65365.1 - 3.5 6.1 11.6 0.93 8.0 3.9 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3683 PF12447.3 GAK65365.1 - 3.7 7.4 6.6 9.1 6.1 0.6 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3683) Syntaxin PF00804.20 GAK65365.1 - 4.1 7.6 13.9 0.087 12.9 3.9 2.3 3 0 0 3 3 2 0 Syntaxin CorA PF01544.13 GAK65365.1 - 9.1 5.2 9.1 1.4 7.9 2.8 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Ank_2 PF12796.2 GAK65366.1 - 3.8e-30 104.0 0.7 7.3e-21 74.3 0.0 2.9 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAK65366.1 - 2.9e-29 100.4 1.8 4.6e-10 39.4 0.1 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 GAK65366.1 - 3.3e-28 96.0 0.7 3.9e-07 29.5 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 GAK65366.1 - 2.8e-26 91.4 1.5 1.9e-12 47.3 0.1 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) FYVE PF01363.16 GAK65366.1 - 5.9e-20 70.9 6.5 5.9e-20 70.9 4.5 2.8 2 1 0 2 2 2 1 FYVE zinc finger Ank_3 PF13606.1 GAK65366.1 - 6.7e-19 66.1 0.6 0.00023 21.0 0.0 5.3 5 0 0 5 5 4 4 Ankyrin repeat zf-RING_2 PF13639.1 GAK65366.1 - 1.9e-10 40.4 3.6 1.9e-10 40.4 2.5 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAK65366.1 - 0.00026 20.9 4.7 0.00026 20.9 3.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) HrpF PF06266.7 GAK65366.1 - 0.0028 17.7 2.2 0.2 11.8 0.2 3.3 2 0 0 2 2 2 1 HrpF protein zf-rbx1 PF12678.2 GAK65366.1 - 0.014 15.4 3.7 0.015 15.3 1.2 2.1 2 0 0 2 2 1 0 RING-H2 zinc finger FYVE_2 PF02318.11 GAK65366.1 - 0.045 13.6 1.1 0.15 11.9 0.7 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger RINGv PF12906.2 GAK65366.1 - 0.049 13.6 3.2 0.18 11.9 2.2 2.0 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 GAK65366.1 - 0.15 11.7 6.7 0.016 14.8 1.1 2.1 2 0 0 2 2 1 0 RING-type zinc-finger FANCL_C PF11793.3 GAK65366.1 - 0.42 10.5 5.6 0.22 11.4 1.6 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain Pex24p PF06398.6 GAK65366.1 - 0.44 9.2 0.3 0.72 8.5 0.2 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PepSY_TM_2 PF13703.1 GAK65367.1 - 0.022 14.9 0.2 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Hist_deacetyl PF00850.14 GAK65368.1 - 8.4e-95 317.6 0.0 1.3e-94 317.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 GAK65368.1 - 4.1e-21 75.1 0.0 9.4e-21 74.0 0.0 1.6 2 0 0 2 2 2 1 Arb2 domain Cutinase PF01083.17 GAK65368.1 - 0.017 14.8 0.2 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 Cutinase UPF0565 PF10561.4 GAK65368.1 - 0.03 13.2 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PTPA PF03095.10 GAK65369.1 - 8.3e-111 369.9 0.0 1e-110 369.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FIST PF08495.5 GAK65370.1 - 1.4e-05 24.3 0.8 0.00025 20.2 0.0 2.9 2 1 1 3 3 3 1 FIST N domain DUF1640 PF07798.6 GAK65371.1 - 2.2e-63 213.4 3.9 2.7e-63 213.2 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) T2SK PF03934.8 GAK65371.1 - 0.0081 15.3 0.2 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K DUF647 PF04884.9 GAK65371.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis HALZ PF02183.13 GAK65371.1 - 0.071 12.8 2.2 0.43 10.3 1.5 2.3 1 1 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 GAK65371.1 - 0.14 12.0 1.5 3.4 7.6 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Arf PF00025.16 GAK65372.1 - 6e-21 74.4 0.0 8.1e-18 64.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 GAK65372.1 - 2.3e-05 23.2 0.0 0.0014 17.3 0.0 2.1 1 1 0 2 2 2 1 G-protein alpha subunit Miro PF08477.8 GAK65372.1 - 3.6e-05 24.2 0.0 6.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAK65372.1 - 0.00011 21.6 0.0 0.00062 19.1 0.0 2.0 2 0 0 2 2 2 1 Ras family Apc13p PF05839.6 GAK65372.1 - 0.0053 16.7 0.0 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 Apc13p protein MMR_HSR1 PF01926.18 GAK65372.1 - 0.0064 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAK65372.1 - 0.023 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.7 GAK65372.1 - 0.024 14.2 0.0 0.44 10.1 0.0 2.3 2 1 1 3 3 3 0 NACHT domain AAA_16 PF13191.1 GAK65372.1 - 0.027 14.4 0.1 0.17 11.8 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAK65372.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAK65372.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 GAK65372.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 3HCDH_N PF02737.13 GAK65373.1 - 7e-45 152.8 5.0 5.9e-44 149.8 3.5 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAK65373.1 - 1.8e-33 114.8 0.0 3.3e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_3 PF13738.1 GAK65373.1 - 0.051 13.6 0.7 0.1 12.6 0.4 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cloacin PF03515.9 GAK65373.1 - 0.11 11.7 0.7 0.17 11.1 0.5 1.3 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain DAO PF01266.19 GAK65373.1 - 0.12 11.2 0.2 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RGS PF00615.14 GAK65374.1 - 2e-37 127.9 0.0 8.2e-37 125.9 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 GAK65374.1 - 2.3e-11 43.2 0.0 4.8e-05 23.0 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.1 GAK65374.1 - 0.02 14.7 0.2 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix SecE PF00584.15 GAK65375.1 - 0.47 10.0 2.1 0.8 9.3 1.4 1.2 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Lipase_3 PF01764.20 GAK65376.1 - 5.1e-28 97.4 0.0 7.8e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 GAK65376.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 GAK65376.1 - 0.086 12.5 0.8 0.14 11.9 0.4 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK65376.1 - 0.12 12.2 3.8 0.099 12.5 0.5 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_6 PF03737.10 GAK65377.1 - 6.8e-25 87.7 0.5 4.4e-23 81.8 0.3 2.4 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase SAP PF02037.22 GAK65377.1 - 3.9e-09 35.7 0.4 6.6e-09 35.0 0.3 1.4 1 0 0 1 1 1 1 SAP domain DsrH PF04077.7 GAK65377.1 - 0.032 13.8 0.0 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 DsrH like protein DUF1539 PF07560.6 GAK65377.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) UPF0172 PF03665.8 GAK65378.1 - 3.2e-41 141.0 0.8 1.2e-40 139.1 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 GAK65378.1 - 0.00042 20.0 0.0 0.00093 18.9 0.0 1.6 1 1 1 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPR_11 PF13414.1 GAK65379.1 - 2.8e-23 81.3 21.5 1e-10 41.1 0.6 7.3 4 1 2 7 7 7 5 TPR repeat TPR_1 PF00515.23 GAK65379.1 - 1.2e-17 62.7 10.5 0.015 14.9 0.0 8.0 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAK65379.1 - 3.4e-17 60.9 23.6 0.055 13.4 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAK65379.1 - 1.1e-13 51.4 40.2 0.00011 22.7 0.0 8.0 5 2 2 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAK65379.1 - 2.6e-12 46.2 27.0 0.034 14.7 0.2 9.5 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 GAK65379.1 - 5.7e-11 41.3 2.7 0.086 12.6 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAK65379.1 - 1.6e-09 37.2 1.7 0.62 10.4 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAK65379.1 - 3.7e-08 33.6 9.6 1.5 9.1 1.4 6.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAK65379.1 - 5.5e-07 29.4 23.1 0.00027 20.8 1.5 6.5 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAK65379.1 - 0.074 12.9 20.4 0.069 13.0 2.6 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAK65379.1 - 0.61 10.6 15.1 27 5.5 0.1 7.8 8 1 1 9 9 9 0 Tetratricopeptide repeat ADK PF00406.17 GAK65380.1 - 3.4e-57 192.5 0.0 4.3e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 GAK65380.1 - 6.6e-14 51.2 0.0 1.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 GAK65380.1 - 9.4e-05 22.3 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAK65380.1 - 0.00078 18.6 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 GAK65380.1 - 0.0085 16.2 0.1 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAK65380.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAK65380.1 - 0.014 16.1 0.0 0.03 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAK65380.1 - 0.045 13.9 0.1 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 GAK65380.1 - 0.062 13.0 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MT0933_antitox PF14013.1 GAK65380.1 - 0.086 12.9 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 MT0933-like antitoxin protein Thymidylate_kin PF02223.12 GAK65380.1 - 0.089 12.1 0.1 2.5 7.4 0.0 2.7 2 1 0 3 3 3 0 Thymidylate kinase Guanylate_kin PF00625.16 GAK65380.1 - 0.092 12.1 0.1 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase Fib_alpha PF08702.5 GAK65380.1 - 0.092 12.8 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family He_PIG PF05345.7 GAK65381.1 - 0.012 15.6 0.0 0.04 13.9 0.0 1.9 1 0 0 1 1 1 0 Putative Ig domain Arrestin_C PF02752.17 GAK65383.1 - 6.6e-17 61.8 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAK65383.1 - 0.015 15.1 0.0 2.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Galactosyl_T PF01762.16 GAK65384.1 - 4.6e-10 39.4 1.4 0.00013 21.6 0.0 3.7 3 1 1 4 4 4 3 Galactosyltransferase SNF2_N PF00176.18 GAK65385.1 - 1.4e-67 227.6 0.0 2.4e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 GAK65385.1 - 2.1e-53 181.0 0.6 4.4e-53 179.9 0.4 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 GAK65385.1 - 3.5e-12 45.9 0.0 1.6e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 GAK65385.1 - 1.8e-08 33.5 0.0 6.4e-08 31.7 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 GAK65385.1 - 6.8e-05 22.7 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAK65385.1 - 0.0039 17.3 0.1 0.3 11.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain L31 PF09784.4 GAK65386.1 - 9.7e-43 144.4 0.4 1.1e-42 144.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 E1-E2_ATPase PF00122.15 GAK65387.1 - 6.2e-65 218.4 1.6 6.2e-65 218.4 1.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAK65387.1 - 3.6e-44 150.4 4.5 4.4e-44 150.1 1.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAK65387.1 - 9.8e-34 117.6 0.0 1.1e-32 114.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK65387.1 - 3.3e-23 80.9 0.0 7.2e-23 79.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAK65387.1 - 2e-19 69.3 0.0 3.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAK65387.1 - 1.7e-18 67.4 0.0 5.1e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAK65387.1 - 6.1e-09 35.8 1.1 9e-06 25.4 0.7 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAK65387.1 - 0.011 16.0 0.1 0.074 13.2 0.0 2.3 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase MarR_2 PF12802.2 GAK65387.1 - 0.046 13.4 0.1 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 MarR family S10_plectin PF03501.10 GAK65390.1 - 6.5e-40 134.9 0.1 8e-40 134.6 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 GAK65390.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Snf7 PF03357.16 GAK65392.1 - 9.6e-23 80.4 13.2 1.5e-22 79.7 9.1 1.2 1 0 0 1 1 1 1 Snf7 DUF3359 PF11839.3 GAK65392.1 - 0.91 9.9 6.1 0.21 11.9 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) DUF948 PF06103.6 GAK65392.1 - 2 8.3 4.1 3.9 7.4 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2360 PF10152.4 GAK65392.1 - 4.4 7.5 11.1 3 8.1 5.5 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) HA2 PF04408.18 GAK65393.1 - 3.7e-16 58.9 0.1 1.2e-15 57.4 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAK65393.1 - 4.3e-13 49.0 0.0 1.2e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAK65393.1 - 4.3e-12 45.7 0.0 1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK65393.1 - 6.7e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAK65393.1 - 5.7e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAK65393.1 - 0.00066 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAK65393.1 - 0.0021 17.0 0.0 0.0056 15.6 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 GAK65393.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 GAK65393.1 - 0.032 13.9 0.3 0.15 11.8 0.2 2.2 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 GAK65393.1 - 0.092 13.0 0.0 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Calpain_III PF01067.17 GAK65394.1 - 3.2e-22 78.7 0.0 8.2e-12 44.9 0.0 5.2 3 2 0 3 3 3 3 Calpain large subunit, domain III Peptidase_C2 PF00648.16 GAK65394.1 - 1.3e-12 47.3 0.0 2.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 GAK65394.1 - 1.4e-07 31.2 0.2 2.4e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 GAK65395.1 - 7.3e-51 172.7 0.0 1.2e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK65395.1 - 1.7e-23 83.0 0.0 5.7e-22 78.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAK65395.1 - 0.0051 15.6 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RPA_interact_N PF14766.1 GAK65395.1 - 0.17 11.4 3.3 0.41 10.1 2.3 1.7 1 0 0 1 1 1 0 Replication protein A interacting N-terminal ubiquitin PF00240.18 GAK65396.1 - 1.8e-137 446.9 21.2 6.1e-34 115.2 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 GAK65396.1 - 1.2e-77 255.5 20.9 6.8e-19 67.3 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAK65396.1 - 3.3e-24 84.9 9.6 0.00019 21.6 0.1 5.7 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAK65396.1 - 4.5e-21 75.2 0.6 0.0016 18.1 0.0 4.1 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAK65396.1 - 6.9e-14 51.6 3.3 0.11 12.4 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAK65396.1 - 1.8e-13 50.4 1.8 0.17 12.0 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAK65396.1 - 1.9e-10 40.6 0.0 1.7 8.7 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 GAK65396.1 - 3.2e-07 30.0 4.9 3.9 7.2 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 GAK65396.1 - 1.3e-06 27.7 0.6 1.2 8.2 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 GAK65396.1 - 5.1e-06 26.2 4.8 7.4 6.5 0.0 4.2 4 0 0 4 4 4 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 GAK65396.1 - 0.00087 19.5 0.8 77 3.7 0.0 4.2 4 0 0 4 4 4 0 ACT domain Plexin_cytopl PF08337.7 GAK65396.1 - 0.0013 17.1 11.9 4.5 5.4 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 GAK65396.1 - 0.0015 17.9 0.0 44 3.4 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) CTDII PF01556.13 GAK65396.1 - 0.024 14.5 13.7 10 6.1 0.2 4.5 1 1 3 4 4 4 0 DnaJ C terminal domain DUF3861 PF12977.2 GAK65396.1 - 0.027 14.5 5.7 71 3.6 0.1 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Tash_PEST PF07708.6 GAK65396.1 - 0.04 13.8 29.1 3.9 7.5 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 GAK65396.1 - 0.078 12.9 7.0 61 3.6 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain MacB_PCD PF12704.2 GAK65396.1 - 0.15 11.5 4.6 48 3.4 0.2 5.0 1 1 4 5 5 5 0 MacB-like periplasmic core domain CDC48_2 PF02933.12 GAK65396.1 - 1.7 8.3 12.9 47 3.7 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 FERM_N PF09379.5 GAK65396.1 - 1.9 8.6 12.1 98 3.1 0.1 5.7 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 GAK65396.1 - 3.3 7.7 7.0 1.9e+02 2.0 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) DHC_N1 PF08385.7 GAK65397.1 - 9.8e-190 631.7 6.4 9.8e-190 631.7 4.5 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 GAK65397.1 - 1.9e-130 435.0 0.5 1.9e-130 435.0 0.4 3.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 GAK65397.1 - 1.3e-79 267.0 0.0 8.1e-79 264.3 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 GAK65397.1 - 5e-27 94.3 0.0 1.7e-14 53.7 0.0 5.5 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 GAK65397.1 - 2e-21 76.1 0.0 4.7e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 GAK65397.1 - 2.3e-19 69.5 0.0 1e-18 67.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 GAK65397.1 - 9.7e-13 48.4 0.0 0.019 15.1 0.0 5.7 4 0 0 4 4 4 3 AAA domain AAA PF00004.24 GAK65397.1 - 4.8e-12 46.2 0.0 0.0053 16.9 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK65397.1 - 2.9e-08 33.9 9.1 0.04 13.9 0.4 7.1 6 1 0 6 6 6 2 AAA ATPase domain AAA_33 PF13671.1 GAK65397.1 - 3.2e-08 33.5 0.2 0.24 11.2 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA_19 PF13245.1 GAK65397.1 - 6.8e-08 32.1 0.6 0.3 10.8 0.0 5.0 4 0 0 4 4 4 2 Part of AAA domain AAA_17 PF13207.1 GAK65397.1 - 1.3e-07 32.5 0.0 2.5 8.9 0.0 5.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 GAK65397.1 - 3.3e-07 30.6 0.0 0.22 11.8 0.0 4.9 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 GAK65397.1 - 5.4e-06 25.4 0.0 0.094 11.6 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 GAK65397.1 - 2.2e-05 23.6 0.8 0.47 9.5 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 GAK65397.1 - 0.00013 21.5 0.2 4.1 6.8 0.0 4.7 4 0 0 4 4 4 1 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 GAK65397.1 - 0.0003 20.8 0.0 12 5.9 0.0 4.7 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_14 PF13173.1 GAK65397.1 - 0.00038 20.3 0.0 0.54 10.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 GAK65397.1 - 0.00054 19.4 2.8 0.36 10.2 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.1 GAK65397.1 - 0.002 17.6 0.0 8.4 6.0 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 GAK65397.1 - 0.011 15.9 0.0 8.5 6.6 0.0 4.0 4 0 0 4 4 4 0 RNA helicase ABC_tran PF00005.22 GAK65397.1 - 0.025 14.8 3.0 22 5.3 0.0 4.8 5 0 0 5 5 4 0 ABC transporter AAA_11 PF13086.1 GAK65397.1 - 0.09 12.3 5.8 2.4 7.6 0.0 4.5 6 0 0 6 6 5 0 AAA domain ResIII PF04851.10 GAK65397.1 - 0.093 12.5 0.0 3.7 7.3 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 GAK65397.1 - 0.19 11.2 0.3 65 3.0 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation LOH1CR12 PF10158.4 GAK65397.1 - 1.2 8.9 9.8 1.4 8.7 0.5 4.2 4 0 0 4 4 4 0 Tumour suppressor protein DUF2346 PF09803.4 GAK65399.1 - 3.4e-06 26.8 5.4 1.8e-05 24.5 3.3 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2346) LMWPc PF01451.16 GAK65400.1 - 3.4e-29 101.9 0.0 3.9e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase adh_short_C2 PF13561.1 GAK65401.1 - 1.8e-09 37.7 0.0 2.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK65401.1 - 1.6e-08 34.6 3.8 3.6e-08 33.4 2.7 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 GAK65401.1 - 0.00055 19.6 0.8 0.00096 18.8 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 GAK65401.1 - 0.015 14.9 2.5 0.017 14.8 0.7 1.9 2 0 0 2 2 2 0 KR domain ApbA PF02558.11 GAK65401.1 - 0.06 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CTDII PF01556.13 GAK65403.1 - 7.1e-28 96.3 0.3 1e-21 76.6 0.0 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 GAK65403.1 - 7.8e-23 79.9 3.3 1.2e-22 79.3 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAK65403.1 - 9.3e-10 38.4 17.3 9.3e-10 38.4 12.0 2.3 3 0 0 3 3 3 1 DnaJ central domain GYF PF02213.11 GAK65404.1 - 1.7e-17 62.7 0.1 1.7e-17 62.7 0.1 1.9 2 0 0 2 2 2 1 GYF domain Hist_deacetyl PF00850.14 GAK65405.1 - 1.2e-80 271.1 0.0 1.7e-80 270.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ATP-synt_F PF01990.12 GAK65406.1 - 1.3e-29 102.3 0.2 1.5e-29 102.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit CorC_HlyC PF03471.12 GAK65406.1 - 0.14 11.9 0.1 1.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Transporter associated domain Abhydrolase_6 PF12697.2 GAK65407.1 - 1.7e-09 37.8 0.2 1.7e-09 37.8 0.2 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 GAK65407.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase MFS_1 PF07690.11 GAK65408.1 - 4e-47 160.6 46.4 2.4e-46 158.0 32.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAK65408.1 - 1.5e-16 59.7 18.2 2.7e-16 58.9 12.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 GAK65409.1 - 5.5e-66 222.9 0.0 6.1e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Suppressor_APC PF11414.3 GAK65409.1 - 0.088 12.5 0.2 33 4.3 0.0 3.5 4 0 0 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein Zn_clus PF00172.13 GAK65410.1 - 4e-07 29.8 10.0 7.5e-07 28.9 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALAD PF00490.16 GAK65411.1 - 7.2e-122 406.3 0.0 8e-122 406.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Amidohydro_2 PF04909.9 GAK65411.1 - 0.014 14.9 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Amidohydrolase Rab15_effector PF15208.1 GAK65411.1 - 0.056 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Rab15 effector RNA_pol_3_Rpc31 PF11705.3 GAK65412.1 - 1.8e-38 132.7 34.5 3.6e-37 128.5 23.9 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Glyco_transf_28 PF03033.15 GAK65413.1 - 6.7e-25 87.4 0.0 1.4e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 GAK65413.1 - 4.8e-14 51.6 0.0 4.1e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 GRAM domain PH PF00169.24 GAK65413.1 - 4.7e-11 42.8 0.1 1.4e-10 41.2 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 GAK65413.1 - 6.9e-07 29.3 0.0 3.7e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 GAK65413.1 - 0.0002 20.0 0.0 0.00036 19.2 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 GAK65413.1 - 0.0041 16.9 0.1 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAK65413.1 - 0.018 15.3 0.2 0.11 12.7 0.1 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Glyco_tran_28_C PF04101.11 GAK65413.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain TPR_11 PF13414.1 GAK65414.1 - 2.5e-53 177.6 30.6 1.6e-15 56.4 0.0 6.4 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 GAK65414.1 - 7.7e-48 158.2 31.7 1.3e-08 34.0 0.4 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAK65414.1 - 1.6e-36 121.2 30.1 4.1e-06 26.3 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 GAK65414.1 - 1.6e-19 70.0 27.9 1.3e-07 32.0 0.1 7.2 4 3 3 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAK65414.1 - 1.9e-19 69.3 25.1 5.6e-12 45.4 0.3 7.2 3 3 6 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAK65414.1 - 5e-18 63.9 23.0 0.02 15.5 0.0 10.5 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAK65414.1 - 1.8e-16 58.6 20.6 0.0036 16.9 0.1 9.4 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAK65414.1 - 1.9e-15 56.9 20.5 9.3e-05 22.6 0.0 7.5 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAK65414.1 - 2.2e-08 33.6 14.3 0.67 10.2 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 GAK65414.1 - 9.4e-08 32.0 16.3 7e-06 26.1 0.9 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAK65414.1 - 1.4e-07 31.2 11.3 0.026 14.3 0.0 7.3 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 GAK65414.1 - 6.8e-07 29.3 15.8 1.6 9.3 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAK65414.1 - 3.4e-06 26.4 29.6 0.033 13.9 0.1 9.4 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAK65414.1 - 0.00037 20.3 12.3 0.084 12.8 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat zf-C2H2_jaz PF12171.3 GAK65414.1 - 0.00073 19.6 0.9 0.025 14.7 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PAS_4 PF08448.5 GAK65414.1 - 0.073 13.1 2.3 2.3 8.3 0.0 3.5 3 0 0 3 3 3 0 PAS fold Inhibitor_I9 PF05922.11 GAK65414.1 - 0.83 10.2 0.0 0.83 10.2 0.0 3.0 4 0 0 4 4 1 0 Peptidase inhibitor I9 Suf PF05843.9 GAK65415.1 - 6.4e-85 285.2 0.2 2e-79 267.2 0.0 4.4 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 GAK65415.1 - 0.012 16.1 26.6 0.46 11.2 0.0 8.2 8 1 1 9 9 9 0 Tetratricopeptide repeat zf-DHHC PF01529.15 GAK65416.1 - 5.3e-16 58.4 0.0 7.4e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase IncA PF04156.9 GAK65416.1 - 0.043 13.4 0.4 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 IncA protein STAG PF08514.6 GAK65417.1 - 1.1e-26 92.7 2.1 4.3e-26 90.9 0.3 2.8 2 1 1 3 3 3 1 STAG domain HEAT PF02985.17 GAK65417.1 - 0.0015 18.4 0.2 1.6 9.0 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat PAS PF00989.19 GAK65418.1 - 4.1e-11 42.6 0.0 3.4e-09 36.4 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 GAK65418.1 - 1.1e-10 41.8 0.0 2.6e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 GAK65418.1 - 3.7e-10 39.8 0.0 1.1e-06 28.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 GAK65418.1 - 6.3e-08 32.6 0.0 1.8e-05 24.7 0.0 2.7 1 1 1 2 2 2 2 PAS fold PAS_11 PF14598.1 GAK65418.1 - 0.003 17.4 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain TauD PF02668.11 GAK65419.1 - 3.1e-38 131.9 0.0 6e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 GAK65419.1 - 6.5e-05 23.2 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 GAK65419.1 - 0.013 14.4 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 CsiD Apt1 PF10351.4 GAK65420.1 - 2e-118 396.1 0.0 2e-118 396.1 0.0 2.5 2 1 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 GAK65420.1 - 6.1e-105 351.3 0.5 6.1e-105 351.3 0.4 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 GAK65420.1 - 3.6e-45 153.6 0.0 7.4e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 GAK65420.1 - 8.8e-37 126.2 0.0 1.6e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 GAK65420.1 - 3.6e-21 75.5 0.0 1.2e-20 73.8 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain PcfK PF14058.1 GAK65422.1 - 0.1 12.7 3.1 0.19 11.8 2.1 1.4 1 0 0 1 1 1 0 PcfK-like protein DUF2360 PF10152.4 GAK65422.1 - 7.7 6.7 10.1 0.55 10.4 1.8 2.7 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Proteasome PF00227.21 GAK65423.1 - 6.1e-57 191.9 0.3 9.8e-57 191.3 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit Ras PF00071.17 GAK65423.1 - 1.1e-44 151.6 0.0 1.8e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK65423.1 - 1.8e-17 63.9 0.0 4.8e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Proteasome_A_N PF10584.4 GAK65423.1 - 1.2e-14 53.3 0.3 2.6e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Arf PF00025.16 GAK65423.1 - 4.7e-06 25.9 0.0 8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK65423.1 - 0.00042 20.2 0.1 0.00086 19.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK65423.1 - 0.00069 19.1 0.0 0.0015 18.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAK65423.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 tRNA-synt_1g PF09334.6 GAK65425.1 - 2.5e-108 362.2 0.3 1.7e-95 319.9 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAK65425.1 - 7.3e-16 57.2 0.0 4.6e-08 31.5 0.0 2.4 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 GAK65425.1 - 4.3e-07 29.3 0.2 0.015 14.4 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 GAK65425.1 - 0.00011 21.9 0.2 0.00045 19.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Peptidase_C28 PF05408.6 GAK65425.1 - 0.034 13.6 0.2 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase tRNA-synt_1f PF01921.13 GAK65425.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Asp PF00026.18 GAK65426.1 - 2.9e-71 240.3 7.6 4.6e-71 239.6 5.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAK65426.1 - 2.4e-08 34.0 1.9 2.4e-08 34.0 1.3 2.5 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal PPR_2 PF13041.1 GAK65427.1 - 1.7e-05 24.6 0.0 9.6e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 GAK65427.1 - 0.00067 19.7 9.9 0.0012 18.9 0.1 5.1 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 GAK65427.1 - 0.0051 16.7 0.0 0.032 14.2 0.0 2.5 1 0 0 1 1 1 1 PPR repeat UPF0261 PF06792.6 GAK65428.1 - 2.1e-116 388.7 0.0 2.9e-116 388.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 GAK65429.1 - 3.3e-128 426.3 0.2 3.8e-128 426.1 0.2 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 GAK65429.1 - 0.0091 15.1 0.2 0.016 14.3 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase SPOR PF05036.8 GAK65429.1 - 0.039 14.1 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain zf-C2H2 PF00096.21 GAK65430.1 - 2.1e-07 30.8 10.3 0.00069 19.8 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK65430.1 - 1.4e-05 25.1 3.8 1.4e-05 25.1 2.7 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAK65430.1 - 1.8e-05 24.7 9.4 0.014 15.7 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAK65430.1 - 0.41 10.6 2.2 0.46 10.4 0.5 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Sugar_tr PF00083.19 GAK65433.1 - 1.3e-114 383.2 22.0 1.5e-114 383.0 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK65433.1 - 9.8e-16 57.3 42.1 7.8e-13 47.8 14.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 GAK65433.1 - 0.1 12.5 3.0 0.38 10.7 2.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) zf-Tim10_DDP PF02953.10 GAK65434.1 - 1.4e-20 72.3 0.6 2e-20 71.8 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Abhydrolase_6 PF12697.2 GAK65435.1 - 1.1e-11 45.0 2.0 1.1e-11 45.0 1.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK65435.1 - 1.2e-11 44.5 0.0 2.6e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 GAK65435.1 - 3.4e-10 39.0 0.0 6.5e-10 38.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.15 GAK65435.1 - 9.2e-05 22.1 0.1 0.0027 17.3 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold MIF4G PF02854.14 GAK65436.1 - 1.4e-28 99.7 0.5 1.5e-27 96.3 0.0 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 GAK65436.1 - 1.4e-26 92.3 0.1 2.9e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 MA3 domain COX6B PF02297.12 GAK65436.1 - 1.1e-23 82.9 0.5 3e-23 81.6 0.4 1.8 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sigma70_ner PF04546.8 GAK65436.1 - 1.9 8.0 8.2 8.8 5.8 1.6 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region CTP_transf_2 PF01467.21 GAK65437.1 - 8.9e-30 103.8 0.0 1.3e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Pox_MCEL PF03291.11 GAK65438.1 - 2.4e-74 250.1 0.0 3.2e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 GAK65438.1 - 3.4e-08 33.3 0.0 8.7e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK65438.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK65438.1 - 3.2e-07 30.0 0.0 5.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK65438.1 - 6.5e-06 26.7 0.0 1.5e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK65438.1 - 7.9e-06 26.2 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK65438.1 - 0.00089 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAK65438.1 - 0.091 11.7 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family tRNA-synt_1 PF00133.17 GAK65439.1 - 1.6e-153 511.9 0.0 2.2e-153 511.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAK65439.1 - 4.5e-28 97.9 0.0 8.5e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAK65439.1 - 4.6e-23 81.5 0.1 3.9e-13 48.8 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAK65439.1 - 0.0012 18.1 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAK65439.1 - 0.21 10.6 0.0 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Zn_clus PF00172.13 GAK65442.1 - 5.1e-06 26.2 7.5 9.9e-06 25.3 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_trans_2_3 PF13632.1 GAK65444.1 - 8.4e-41 139.8 2.7 8.4e-41 139.8 1.8 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK65444.1 - 2.2e-08 34.1 0.0 6.1e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAK65444.1 - 3.5e-05 23.5 0.0 0.0037 16.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAK65444.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 GAK65446.1 - 1.8e-20 72.9 0.5 5.3e-20 71.4 0.2 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 GAK65446.1 - 0.31 10.3 4.5 0.47 9.8 3.1 1.2 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_16 PF00722.16 GAK65447.1 - 3.6e-22 78.5 1.0 6.8e-22 77.6 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 GAK65448.1 - 1.2e-41 142.5 2.0 1.2e-41 142.5 1.4 2.6 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK65448.1 - 2.1e-07 30.9 0.1 9e-07 28.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAK65448.1 - 0.0041 16.8 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cutinase PF01083.17 GAK65450.1 - 1.7e-17 63.7 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase PAP2 PF01569.16 GAK65453.1 - 2.9e-19 69.0 3.2 2.9e-19 69.0 2.2 2.8 3 1 1 4 4 4 1 PAP2 superfamily AAA PF00004.24 GAK65454.1 - 1.9e-85 283.6 0.0 3.7e-42 143.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAK65454.1 - 1.3e-13 50.8 0.0 3.3e-07 30.1 0.0 3.8 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAK65454.1 - 2.5e-12 47.1 1.9 8.4e-06 25.8 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain RuvB_N PF05496.7 GAK65454.1 - 3.8e-11 42.4 0.0 6.8e-05 22.0 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAK65454.1 - 8.3e-10 38.9 0.3 0.00036 20.6 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAK65454.1 - 2.7e-09 37.9 0.0 4.3e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 GAK65454.1 - 3.7e-09 35.7 0.0 0.0017 17.1 0.0 2.6 3 0 0 3 3 3 2 TIP49 C-terminus AAA_33 PF13671.1 GAK65454.1 - 1.2e-07 31.6 0.0 0.0001 22.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAK65454.1 - 1.9e-07 31.0 0.0 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAK65454.1 - 4.4e-07 29.4 2.9 0.011 15.1 0.1 4.3 2 2 1 4 4 4 1 AAA domain Zeta_toxin PF06414.7 GAK65454.1 - 5.2e-07 28.9 0.0 0.00025 20.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 GAK65454.1 - 2.2e-06 27.1 0.0 0.01 15.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.9 GAK65454.1 - 3.8e-06 26.9 0.0 0.16 11.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 GAK65454.1 - 9.1e-06 25.7 0.0 0.047 13.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 GAK65454.1 - 9.1e-06 25.3 2.1 0.0029 17.3 0.2 3.5 3 0 0 3 3 3 1 Part of AAA domain AAA_28 PF13521.1 GAK65454.1 - 1.3e-05 25.2 0.1 0.02 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAK65454.1 - 2e-05 24.7 0.0 0.091 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 GAK65454.1 - 4.4e-05 22.7 0.5 0.23 10.6 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAK65454.1 - 0.00028 21.1 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAK65454.1 - 0.00046 19.8 0.9 0.017 14.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 GAK65454.1 - 0.0011 18.6 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAK65454.1 - 0.0017 18.0 0.1 1.4 8.5 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase Sigma54_activat PF00158.21 GAK65454.1 - 0.0021 17.5 0.0 1.8 8.0 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 GAK65454.1 - 0.0026 16.5 0.0 0.14 10.8 0.0 2.6 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 GAK65454.1 - 0.0027 16.6 0.0 0.24 10.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.8 GAK65454.1 - 0.0027 16.6 0.0 0.04 12.8 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 GAK65454.1 - 0.0083 15.7 0.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 GAK65454.1 - 0.0084 15.7 0.1 0.52 9.9 0.0 3.1 3 1 0 4 4 3 1 NACHT domain DAP3 PF10236.4 GAK65454.1 - 0.016 14.1 0.0 0.036 13.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PhoH PF02562.11 GAK65454.1 - 0.017 14.3 0.3 0.71 9.0 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 GAK65454.1 - 0.018 15.3 0.0 0.92 9.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.1 GAK65454.1 - 0.018 14.6 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 GAK65454.1 - 0.025 13.6 0.0 2.9 6.9 0.0 2.6 2 0 0 2 2 2 0 KaiC SKI PF01202.17 GAK65454.1 - 0.035 13.9 0.1 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.1 GAK65454.1 - 0.041 14.1 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 GAK65454.1 - 0.054 12.6 0.2 1.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.10 GAK65454.1 - 0.11 12.1 0.8 3.5 7.3 0.0 3.1 2 2 2 4 4 3 0 NTPase GDI PF00996.13 GAK65455.1 - 7.8e-53 179.3 0.0 8.5e-51 172.6 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Sas10_Utp3 PF04000.10 GAK65456.1 - 1.5e-10 41.0 0.1 3.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Zn_clus PF00172.13 GAK65457.1 - 2.4e-05 24.1 9.2 6e-05 22.8 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKN1 PF03935.10 GAK65458.1 - 2e-202 672.8 0.0 2.5e-202 672.5 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 GAK65458.1 - 2.7e-06 26.8 0.9 0.00044 19.5 0.0 3.1 4 0 0 4 4 4 2 Glycosyl hydrolases family 16 zf-C2H2 PF00096.21 GAK65459.1 - 1.1e-12 47.4 14.0 7.3e-06 26.0 0.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK65459.1 - 9.3e-11 41.2 14.2 0.00043 20.4 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAK65459.1 - 1.4e-05 25.1 14.3 0.033 14.5 0.6 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 GAK65459.1 - 0.19 11.8 4.8 4.8 7.3 3.5 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.1 GAK65459.1 - 0.48 10.0 3.4 3.4 7.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.10 GAK65459.1 - 0.5 10.1 2.4 9.5 6.0 0.0 2.4 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_4 PF13717.1 GAK65459.1 - 0.78 9.4 4.0 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 GAK65459.1 - 1.9 8.7 5.2 3.8 7.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 GAK65459.1 - 3.8 7.4 9.4 7.8 6.3 0.8 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Thiolase_N PF00108.18 GAK65460.1 - 8.1e-94 313.4 4.9 4.7e-47 160.1 0.7 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAK65460.1 - 3.8e-45 152.2 3.4 2.1e-44 149.8 0.7 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAK65460.1 - 2.6e-05 23.8 7.2 0.00029 20.4 1.3 2.9 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain BcrAD_BadFG PF01869.15 GAK65460.1 - 0.0063 15.8 1.5 0.014 14.6 0.1 2.2 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family Seryl_tRNA_N PF02403.17 GAK65461.1 - 0.17 11.9 3.4 0.37 10.8 2.4 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AT_hook PF02178.14 GAK65462.1 - 1.1e-07 30.6 85.9 0.047 13.3 1.7 8.7 8 0 0 8 8 8 7 AT hook motif SlyX PF04102.7 GAK65462.1 - 0.08 13.3 1.6 0.21 11.9 1.1 1.7 1 0 0 1 1 1 0 SlyX CENP-F_N PF10481.4 GAK65462.1 - 3.5 6.8 9.0 6 6.1 1.3 3.2 2 1 1 3 3 3 0 Cenp-F N-terminal domain DUF1191 PF06697.7 GAK65463.1 - 0.00087 18.1 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) SKG6 PF08693.5 GAK65463.1 - 0.0027 16.9 0.1 0.0074 15.5 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 GAK65463.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 GAK65463.1 - 0.021 13.0 2.5 0.088 11.0 0.0 2.5 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 GAK65463.1 - 0.026 14.1 0.1 0.068 12.8 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain WBP-1 PF11669.3 GAK65463.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 IncA PF04156.9 GAK65463.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.1 3 0 0 3 3 3 0 IncA protein Shisa PF13908.1 GAK65463.1 - 0.35 11.0 0.0 0.35 11.0 0.0 3.5 2 1 0 3 3 3 0 Wnt and FGF inhibitory regulator DAP10 PF07213.6 GAK65463.1 - 2.9 7.7 7.2 0.3 10.8 0.1 2.6 2 0 0 2 2 2 0 DAP10 membrane protein Syndecan PF01034.15 GAK65464.1 - 0.012 15.2 0.3 0.023 14.3 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 GAK65464.1 - 0.089 12.1 0.3 0.22 10.8 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 GAK65464.1 - 0.09 12.3 0.1 0.22 11.0 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 GAK65464.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAD_binding_1 PF00667.15 GAK65465.1 - 1.8e-51 174.7 0.0 3e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAK65465.1 - 6.9e-08 33.0 0.1 3.1e-07 30.9 0.0 2.2 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAK65465.1 - 0.053 13.6 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain APG12 PF04110.8 GAK65466.1 - 1.3e-32 111.7 0.0 2e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 GAK65466.1 - 0.0026 17.7 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like HD-ZIP_N PF04618.7 GAK65466.1 - 0.069 13.6 0.8 3.6 8.1 0.5 2.4 2 0 0 2 2 2 0 HD-ZIP protein N terminus Ribosomal_L30_N PF08079.7 GAK65467.1 - 1.2e-24 86.0 18.6 1.9e-24 85.4 12.9 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 GAK65467.1 - 9.7e-18 63.5 1.6 2.5e-17 62.2 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e NinG PF05766.7 GAK65467.1 - 0.46 10.2 5.9 0.86 9.3 4.1 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Alk_phosphatase PF00245.15 GAK65468.1 - 8.1e-76 255.3 0.0 2.8e-66 223.9 0.0 2.1 2 0 0 2 2 2 2 Alkaline phosphatase Annexin PF00191.15 GAK65469.1 - 3.5e-57 190.1 2.7 3.3e-18 65.3 0.0 4.4 4 1 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 GAK65469.1 - 0.0024 18.0 0.3 2.3 8.5 0.0 3.5 4 0 0 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 LRR_4 PF12799.2 GAK65470.1 - 0.00046 19.7 0.4 0.39 10.4 0.0 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 GAK65470.1 - 0.11 12.7 1.4 30 5.4 0.0 4.1 5 0 0 5 5 5 0 Leucine rich repeat Y_phosphatase2 PF03162.8 GAK65471.1 - 5.2e-49 165.7 0.0 9.2e-49 164.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Prefoldin PF02996.12 GAK65471.1 - 1e-28 99.3 0.2 1.5e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Y_phosphatase3 PF13350.1 GAK65471.1 - 2.5e-08 34.3 0.0 2.6e-06 27.7 0.0 2.7 2 1 1 3 3 3 1 Tyrosine phosphatase family OHCU_decarbox PF09349.5 GAK65472.1 - 1.3e-30 106.8 2.2 1.3e-30 106.7 0.0 2.1 2 1 0 2 2 2 1 OHCU decarboxylase adh_short PF00106.20 GAK65473.1 - 1.8e-34 119.0 1.5 3.3e-34 118.2 1.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAK65473.1 - 2.1e-14 53.6 0.2 3e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK65473.1 - 2.1e-09 37.5 0.0 2.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAK65473.1 - 0.00011 21.7 0.1 0.00018 21.0 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAK65473.1 - 0.00011 21.9 0.1 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 GAK65473.1 - 0.00025 20.7 0.6 0.00049 19.8 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAK65473.1 - 0.00088 18.4 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAK65473.1 - 0.0012 18.8 4.0 0.0034 17.4 1.7 2.5 2 1 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 GAK65473.1 - 0.0019 17.3 0.0 0.0044 16.1 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 GAK65473.1 - 0.0089 15.0 0.2 0.012 14.6 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 GAK65473.1 - 0.028 13.8 0.7 0.057 12.8 0.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 GAK65473.1 - 0.06 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAK65473.1 - 0.072 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DASH_Dad3 PF08656.5 GAK65475.1 - 8e-21 73.5 0.7 1.2e-20 72.9 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad3 Abhydrolase_6 PF12697.2 GAK65476.1 - 2.6e-30 105.9 4.2 3.4e-30 105.6 2.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK65476.1 - 2.3e-16 60.0 0.2 3.3e-16 59.5 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK65476.1 - 8.5e-12 45.0 0.0 2.3e-11 43.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAK65476.1 - 1.3e-05 24.9 0.0 0.00012 21.8 0.0 2.2 1 1 1 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 GAK65476.1 - 0.012 14.1 0.0 0.026 12.9 0.0 1.5 2 0 0 2 2 2 0 Ndr family Prok-RING_4 PF14447.1 GAK65476.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PAE PF03283.8 GAK65478.1 - 2e-15 56.3 0.5 2.9e-15 55.7 0.3 1.1 1 0 0 1 1 1 1 Pectinacetylesterase RNA_pol_I_A49 PF06870.7 GAK65480.1 - 8.1e-126 419.6 0.7 1.3e-125 418.9 0.0 1.6 2 0 0 2 2 2 1 A49-like RNA polymerase I associated factor TMEM247 PF15444.1 GAK65480.1 - 0.85 9.4 0.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 247 PHP PF02811.14 GAK65481.1 - 4.1e-09 36.4 0.3 5.5e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 PHP domain FA_hydroxylase PF04116.8 GAK65482.1 - 5e-14 52.6 26.1 7.6e-14 52.0 15.3 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Mtc PF03820.12 GAK65483.1 - 9.8e-94 313.4 0.1 1.2e-93 313.1 0.1 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.27 GAK65484.1 - 1.4e-43 145.2 13.6 5.8e-09 35.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF2415 PF10313.4 GAK65484.1 - 0.0012 18.5 0.0 0.0099 15.5 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) DAZAP2 PF11029.3 GAK65484.1 - 0.11 12.9 3.6 0.27 11.6 2.5 1.6 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) gag_pre-integrs PF13976.1 GAK65484.1 - 0.13 11.9 1.2 5.6 6.6 0.4 2.9 3 0 0 3 3 3 0 GAG-pre-integrase domain p450 PF00067.17 GAK65486.1 - 1.5e-26 93.0 0.1 4.5e-26 91.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Septin PF00735.13 GAK65487.1 - 3.2e-113 377.4 0.2 3.2e-113 377.4 0.1 1.8 2 0 0 2 2 2 1 Septin ENTH PF01417.15 GAK65487.1 - 1.5e-50 170.2 0.2 3.4e-50 169.0 0.1 1.7 1 0 0 1 1 1 1 ENTH domain MMR_HSR1 PF01926.18 GAK65487.1 - 5.4e-08 32.7 0.0 1.8e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAK65487.1 - 7.1e-07 28.5 0.1 1.9e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 GAK65487.1 - 1.3e-05 24.6 5.0 4.6e-05 22.9 0.2 3.4 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Ras PF00071.17 GAK65487.1 - 0.00014 21.3 0.1 0.00043 19.7 0.1 1.9 1 0 0 1 1 1 1 Ras family AAA_24 PF13479.1 GAK65487.1 - 0.00036 20.1 0.0 0.0013 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 GAK65487.1 - 0.0011 18.1 0.1 0.0032 16.6 0.0 1.8 1 0 0 1 1 1 1 AIG1 family UIM PF02809.15 GAK65487.1 - 0.0027 17.1 11.1 0.01 15.3 1.0 3.7 3 0 0 3 3 3 1 Ubiquitin interaction motif AAA_10 PF12846.2 GAK65487.1 - 0.0031 16.9 0.0 0.0031 16.9 0.0 2.4 2 1 1 3 3 3 1 AAA-like domain MobB PF03205.9 GAK65487.1 - 0.0046 16.6 0.8 0.026 14.2 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 GAK65487.1 - 0.0056 17.1 0.2 0.0056 17.1 0.1 2.0 2 0 0 2 2 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAK65487.1 - 0.0058 15.7 0.0 0.018 14.1 0.0 1.9 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAK65487.1 - 0.017 15.2 0.0 0.017 15.2 0.0 2.8 4 0 0 4 4 2 0 AAA domain AAA_16 PF13191.1 GAK65487.1 - 0.019 14.9 0.0 0.019 14.9 0.0 3.5 5 0 0 5 5 3 0 AAA ATPase domain ABC_tran PF00005.22 GAK65487.1 - 0.022 15.0 0.0 0.022 15.0 0.0 3.3 2 1 0 2 2 1 0 ABC transporter PduV-EutP PF10662.4 GAK65487.1 - 0.03 13.8 2.1 0.28 10.6 0.1 2.7 2 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 GAK65487.1 - 0.033 13.8 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF3235 PF11574.3 GAK65487.1 - 0.053 13.7 3.3 0.16 12.2 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) AAA_29 PF13555.1 GAK65487.1 - 0.072 12.6 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 GAK65487.1 - 0.097 11.9 0.0 0.28 10.4 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 GAK65487.1 - 0.18 12.0 1.8 1.7 8.8 0.1 3.0 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAK65487.1 - 0.44 10.8 0.0 0.44 10.8 0.0 3.3 3 1 0 3 3 1 0 AAA domain RNA_helicase PF00910.17 GAK65487.1 - 0.63 10.2 0.0 0.63 10.2 0.0 3.1 3 0 0 3 3 2 0 RNA helicase zf-CSL PF05207.8 GAK65488.1 - 7.7e-25 86.1 1.6 7.7e-25 86.1 1.1 1.4 2 0 0 2 2 2 1 CSL zinc finger zf-RING_4 PF14570.1 GAK65488.1 - 0.0029 17.1 0.7 0.0047 16.4 0.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 GAK65488.1 - 0.0068 15.9 1.0 0.011 15.3 0.7 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.5 GAK65488.1 - 0.0086 16.0 0.4 0.015 15.2 0.3 1.5 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_4 PF13717.1 GAK65488.1 - 0.021 14.5 1.2 0.033 13.8 0.8 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF164 PF02591.10 GAK65488.1 - 0.074 12.8 0.1 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Putative zinc ribbon domain Ras PF00071.17 GAK65489.1 - 1.1e-55 187.4 0.1 1.3e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK65489.1 - 5.2e-18 65.6 0.0 6.7e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK65489.1 - 1.3e-16 60.3 0.0 1.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK65489.1 - 3.3e-05 23.8 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK65489.1 - 0.00045 19.6 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAK65489.1 - 0.00072 18.7 0.0 0.00087 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAK65489.1 - 0.0069 15.6 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 GAK65489.1 - 0.052 13.1 0.1 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAK65489.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 GAK65489.1 - 0.15 11.3 0.0 14 4.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Pil1 PF13805.1 GAK65490.1 - 1.1e-09 37.8 0.9 1.1e-09 37.8 0.6 2.2 2 0 0 2 2 2 1 Eisosome component PIL1 IMD PF08397.6 GAK65490.1 - 0.011 15.0 2.6 1.8 7.8 0.4 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain Glyco_hydro_32N PF00251.15 GAK65492.1 - 4.5e-49 167.4 0.0 6.6e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAK65492.1 - 2.7e-09 37.2 0.0 6.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 GAK65492.1 - 0.052 13.3 1.2 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 BNR/Asp-box repeat EPSP_synthase PF00275.15 GAK65497.1 - 1.5e-115 386.0 0.1 2.1e-115 385.5 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 GAK65497.1 - 5.5e-96 320.4 0.0 1.9e-95 318.7 0.0 1.9 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 GAK65497.1 - 2.6e-62 210.3 0.0 4.6e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 GAK65497.1 - 5.4e-27 94.5 0.0 1e-25 90.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 GAK65497.1 - 3.8e-26 90.9 0.0 1.3e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAK65497.1 - 1.4e-09 38.1 0.0 3.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 GAK65497.1 - 2.3e-05 23.8 0.1 0.0001 21.6 0.0 2.1 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase OCD_Mu_crystall PF02423.10 GAK65497.1 - 0.0038 16.0 0.5 0.098 11.3 0.1 2.4 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family SURF6 PF04935.7 GAK65498.1 - 3.2e-49 167.1 34.1 3.2e-49 167.1 23.6 3.2 3 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 GAK65498.1 - 7.7e-15 54.7 5.5 7.7e-15 54.7 3.8 6.1 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 WD40 PF00400.27 GAK65499.1 - 3.8e-80 261.1 28.7 2.3e-13 49.4 0.0 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 GAK65499.1 - 2.4e-07 29.2 2.4 0.0014 16.8 0.0 4.2 3 1 2 5 5 5 2 Nucleoporin Nup120/160 NLE PF08154.7 GAK65499.1 - 4.2e-06 26.6 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 GAK65499.1 - 0.00019 21.2 0.0 0.0017 18.0 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 GAK65499.1 - 0.032 13.8 0.3 1.2 8.9 0.0 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 GAK65499.1 - 0.038 13.0 0.2 2.8 6.9 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 GAK65499.1 - 0.07 12.4 1.4 6.4 6.2 0.1 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PAP2 PF01569.16 GAK65500.1 - 1.5e-20 73.1 2.9 1.5e-20 73.1 2.0 2.1 2 0 0 2 2 2 1 PAP2 superfamily TRAM_LAG1_CLN8 PF03798.11 GAK65501.1 - 2.9e-42 144.4 22.1 2.9e-42 144.4 15.3 2.7 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.6 GAK65501.1 - 4.5e-08 32.4 0.3 4.6e-07 29.2 0.0 2.7 3 0 0 3 3 3 1 TRAM1-like protein MFS_1 PF07690.11 GAK65502.1 - 5.5e-31 107.5 24.7 5.5e-31 107.5 17.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAK65505.1 - 2.3e-32 111.8 0.0 3.6e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65505.1 - 6.1e-10 38.8 8.8 1e-09 38.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CbiK PF06180.6 GAK65506.1 - 0.14 11.2 0.0 0.82 8.7 0.0 1.9 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) GMC_oxred_N PF00732.14 GAK65507.1 - 2e-56 191.3 0.0 2.6e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK65507.1 - 1.6e-37 128.9 0.1 3.7e-37 127.8 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAK65507.1 - 2.3e-05 23.4 0.6 0.068 12.0 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAK65507.1 - 0.00071 18.5 0.2 0.006 15.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAK65507.1 - 0.00087 19.3 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK65507.1 - 0.0014 17.6 0.1 0.0021 17.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAK65507.1 - 0.019 14.9 0.6 0.056 13.4 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAK65507.1 - 0.03 12.7 0.4 4.7 5.5 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 GAK65507.1 - 0.046 12.8 0.2 0.088 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Metallophos PF00149.23 GAK65509.1 - 5.6e-11 42.2 0.0 3.7e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAK65509.1 - 3.4e-05 23.7 0.0 0.00051 19.9 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Npa1 PF11707.3 GAK65510.1 - 5.5e-102 341.1 0.0 1.5e-101 339.6 0.0 1.8 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Phos_pyr_kin PF08543.7 GAK65511.1 - 7.6e-73 244.7 0.0 2.4e-55 187.4 0.0 2.9 2 1 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 GAK65511.1 - 2e-36 125.7 0.5 4.3e-36 124.6 0.1 1.8 2 0 0 2 2 2 1 TENA/THI-4/PQQC family MFS_1 PF07690.11 GAK65511.1 - 1.1e-26 93.4 27.7 2.4e-26 92.3 16.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HK PF02110.10 GAK65511.1 - 0.25 10.4 0.8 14 4.7 0.0 2.3 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Zn_clus PF00172.13 GAK65514.1 - 0.00046 20.0 8.9 0.00086 19.1 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 GAK65515.1 - 3.4e-15 56.7 0.3 2.8e-14 53.7 0.0 2.4 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 GAK65515.1 - 2.5e-06 27.3 0.0 1.1e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Nop14 PF04147.7 GAK65515.1 - 0.24 9.3 28.1 0.47 8.3 19.4 1.4 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.6 GAK65515.1 - 6.1 5.0 21.6 12 4.1 15.0 1.4 1 0 0 1 1 1 0 SGT1 protein Daxx PF03344.10 GAK65515.1 - 10 4.4 25.4 30 2.9 17.6 1.7 1 0 0 1 1 1 0 Daxx Family Steroid_dh PF02544.11 GAK65516.1 - 2.1e-34 118.4 5.1 2.8e-34 118.0 3.5 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 GAK65516.1 - 0.00017 20.8 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family PEMT PF04191.8 GAK65516.1 - 0.00051 20.0 1.3 0.0063 16.6 0.2 2.4 1 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAK65516.1 - 0.0014 17.9 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 GAK65516.1 - 0.0047 17.0 1.2 0.0081 16.3 0.2 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ubiquitin_2 PF14560.1 GAK65516.1 - 0.031 14.5 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UAE_UbL PF14732.1 GAK65516.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain EmrE PF13536.1 GAK65516.1 - 3.5 7.8 8.1 0.39 10.9 1.1 2.3 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Glyco_hydro_20 PF00728.17 GAK65517.1 - 8.2e-30 104.1 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain MMS19_N PF14500.1 GAK65518.1 - 2.4e-62 210.6 0.0 1.1e-49 169.1 0.0 3.9 3 1 0 3 3 3 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 GAK65518.1 - 6.4e-47 160.1 0.0 1.3e-45 155.9 0.0 2.9 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal Arm PF00514.18 GAK65518.1 - 0.0024 17.6 2.4 5.4 6.9 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAK65518.1 - 0.016 15.2 7.9 35 4.8 0.1 6.8 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 GAK65518.1 - 0.45 11.0 19.5 13 6.3 0.3 7.8 6 2 2 8 8 8 0 HEAT-like repeat DUF2360 PF10152.4 GAK65518.1 - 9.8 6.4 6.6 6.7 6.9 2.5 2.3 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) AT_hook PF02178.14 GAK65519.1 - 0.0022 17.4 11.4 0.072 12.7 1.8 3.3 2 0 0 2 2 2 2 AT hook motif Mito_fiss_reg PF05308.6 GAK65520.1 - 0.071 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Aminotran_5 PF00266.14 GAK65521.1 - 3.3e-26 91.8 0.0 7.1e-26 90.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 GAK65521.1 - 1.1e-20 73.5 0.0 2.4e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAK65521.1 - 1.1e-14 54.1 0.0 2.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Peptidase_S49 PF01343.13 GAK65522.1 - 1.5e-48 164.4 0.0 1.1e-27 96.6 0.0 3.2 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.18 GAK65522.1 - 3.8e-05 23.4 3.0 0.00052 19.7 0.0 3.1 4 0 0 4 4 4 1 Clp protease SDH_sah PF01972.11 GAK65522.1 - 0.015 14.0 0.0 0.051 12.3 0.0 1.8 2 0 0 2 2 2 0 Serine dehydrogenase proteinase CHCH PF06747.8 GAK65523.1 - 5.8e-08 32.4 4.2 1.1e-07 31.6 2.9 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 GAK65523.1 - 0.026 14.6 3.2 0.11 12.6 2.2 2.0 1 0 0 1 1 1 0 GCK domain Spc7 PF08317.6 GAK65523.1 - 1.1 7.8 15.1 5.4 5.5 10.4 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein CCDC-167 PF15188.1 GAK65523.1 - 6.7 6.7 14.2 0.41 10.6 5.3 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Sec6 PF06046.8 GAK65524.1 - 4.1e-159 530.2 0.0 5.4e-159 529.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 MutS_III PF05192.13 GAK65524.1 - 0.02 14.6 0.0 0.078 12.7 0.0 2.1 1 1 0 1 1 1 0 MutS domain III NPV_P10 PF05531.7 GAK65524.1 - 0.052 13.8 1.1 0.32 11.2 0.0 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fungal_trans PF04082.13 GAK65525.1 - 2.2e-25 89.0 0.0 3.7e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65525.1 - 4.6e-07 29.6 7.6 7.5e-07 28.9 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.17 GAK65527.1 - 1.3e-23 83.3 0.0 2.2e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 GAK65527.1 - 2e-22 79.2 0.0 2.8e-18 65.7 0.0 2.1 2 0 0 2 2 2 2 NAD synthase MFS_1 PF07690.11 GAK65528.1 - 1.5e-28 99.5 27.8 1.5e-28 99.5 19.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK65528.1 - 1.8e-12 46.5 3.1 1.8e-12 46.5 2.2 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2823 PF11034.3 GAK65528.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2823) DUF4385 PF14328.1 GAK65529.1 - 1.4e-53 180.7 0.5 2.3e-53 179.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) TROVE PF05731.6 GAK65529.1 - 0.037 12.7 1.3 0.05 12.3 0.9 1.1 1 0 0 1 1 1 0 TROVE domain GMC_oxred_N PF00732.14 GAK65530.1 - 4.9e-53 180.2 3.8 3.1e-52 177.5 2.7 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK65530.1 - 3.6e-30 105.1 0.0 6.9e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAK65530.1 - 5.7e-09 35.3 1.1 0.0012 17.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAK65530.1 - 2.2e-06 27.5 0.1 6.6e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK65530.1 - 1.3e-05 24.2 0.9 0.0023 16.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAK65530.1 - 2.8e-05 24.2 0.4 0.031 14.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Endotoxin_mid PF09131.5 GAK65530.1 - 5.4e-05 22.7 0.4 0.00013 21.4 0.2 1.6 1 0 0 1 1 1 1 Bacillus thuringiensis delta-Endotoxin, middle domain Lycopene_cycl PF05834.7 GAK65530.1 - 0.00015 20.8 0.1 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAK65530.1 - 0.018 14.9 0.1 0.018 14.9 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK65530.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 GAK65530.1 - 0.082 11.9 0.5 0.22 10.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family RNA_pol_A_bac PF01000.21 GAK65531.1 - 3.9e-27 94.6 0.0 1.4e-26 92.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAK65531.1 - 1.5e-14 52.8 0.0 2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 GAK65531.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 MIF4G PF02854.14 GAK65532.1 - 2.7e-47 160.9 0.0 2.2e-24 86.0 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 GAK65532.1 - 2.6e-13 50.0 22.4 2.6e-13 50.0 15.5 3.8 3 1 1 4 4 4 1 Up-frameshift suppressor 2 SAC3_GANP PF03399.11 GAK65534.1 - 9.2e-54 182.0 0.0 1.3e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family MFS_1 PF07690.11 GAK65535.1 - 4.4e-34 117.7 49.9 1.1e-28 99.9 21.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CDP-OH_P_tran_2 PF08009.6 GAK65535.1 - 1.4 8.6 7.5 0.11 12.2 0.7 2.5 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 DUF3671 PF12420.3 GAK65535.1 - 5.8 6.9 5.7 2.5 8.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function ApoLp-III PF07464.6 GAK65537.1 - 0.024 14.6 15.3 0.022 14.7 2.0 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Reo_sigmaC PF04582.7 GAK65537.1 - 0.13 11.4 2.2 0.13 11.4 0.2 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 GAK65537.1 - 6.4 6.3 7.4 20 4.7 1.3 2.9 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 GAK65538.1 - 2e-09 37.2 13.5 3.5e-09 36.4 9.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAK65538.1 - 1.7e-08 34.1 9.6 1.7e-08 34.1 6.6 2.3 1 1 1 2 2 2 1 Basic region leucine zipper TfuA PF07812.7 GAK65538.1 - 0.033 13.6 0.2 0.092 12.1 0.1 1.8 1 0 0 1 1 1 0 TfuA-like protein TSC22 PF01166.13 GAK65538.1 - 0.12 12.3 1.7 0.25 11.3 1.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family IncA PF04156.9 GAK65538.1 - 5 6.6 13.9 0.65 9.5 6.2 1.9 2 1 0 2 2 2 0 IncA protein Spt5_N PF11942.3 GAK65538.1 - 5.7 7.6 20.8 1.4 9.6 11.2 2.3 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_S8e PF01201.17 GAK65541.1 - 6.7e-50 168.6 1.7 8.1e-50 168.3 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e tRNA-synt_1 PF00133.17 GAK65542.1 - 4.7e-216 718.4 0.0 2.1e-215 716.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAK65542.1 - 5.9e-38 130.0 0.6 1.4e-37 128.7 0.4 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAK65542.1 - 5.1e-19 68.1 0.3 2e-09 36.6 0.1 4.5 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAK65542.1 - 8.8e-12 44.7 3.9 1.3e-07 31.0 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 GAK65542.1 - 0.0064 15.3 0.0 0.08 11.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 GAK65542.1 - 0.0073 15.4 0.0 0.57 9.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF3502 PF12010.3 GAK65542.1 - 0.017 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) tRNA-synt_1c PF00749.16 GAK65542.1 - 0.12 11.0 0.3 2.8 6.5 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Methyltransf_23 PF13489.1 GAK65543.1 - 4e-10 39.6 0.0 9e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK65543.1 - 5.2e-06 26.8 0.0 9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK65543.1 - 2.4e-05 24.7 0.0 5.4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK65543.1 - 0.00011 21.8 0.0 0.00037 20.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK65543.1 - 0.0026 18.3 0.0 0.0039 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 GAK65543.1 - 0.0039 16.7 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Fungal_trans PF04082.13 GAK65544.1 - 1e-12 47.4 0.0 2.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65544.1 - 9.7e-06 25.4 12.7 1.7e-05 24.5 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0261 PF06792.6 GAK65544.1 - 0.13 10.6 2.0 0.22 9.9 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Aminotran_1_2 PF00155.16 GAK65545.1 - 2.6e-41 141.7 0.0 4e-41 141.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAK65545.1 - 0.00098 17.5 0.0 0.0018 16.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAK65545.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pectinesterase PF01095.14 GAK65546.1 - 1.7e-33 115.4 0.1 8.6e-32 109.8 0.1 2.1 1 1 0 1 1 1 1 Pectinesterase NAD_binding_10 PF13460.1 GAK65547.1 - 8.4e-23 81.3 0.0 1.1e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAK65547.1 - 3.6e-05 23.3 0.0 4.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAK65547.1 - 0.0098 15.1 0.1 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 GAK65547.1 - 0.042 12.7 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein HAD_2 PF13419.1 GAK65548.1 - 1.4e-27 97.0 0.4 2.8e-27 96.0 0.3 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 GAK65548.1 - 7.6e-16 57.3 0.1 2.9e-07 30.0 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.2 GAK65548.1 - 2.8e-13 49.3 0.3 5.5e-13 48.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK65548.1 - 5.4e-10 38.6 0.2 1.8e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 F-box domain Hydrolase_like PF13242.1 GAK65548.1 - 0.016 14.9 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like TB2_DP1_HVA22 PF03134.14 GAK65549.1 - 1.7e-32 110.9 6.7 2.6e-32 110.4 4.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CENP-I PF07778.6 GAK65550.1 - 3.8e-20 71.5 0.7 1.1e-15 56.9 0.0 3.8 4 0 0 4 4 4 3 Mis6 AA_permease_2 PF13520.1 GAK65552.1 - 1.7e-55 188.2 56.1 2.1e-55 187.9 38.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAK65552.1 - 1.7e-19 69.5 51.2 2.4e-19 69.0 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 GAK65553.1 - 1.4e-178 593.9 0.3 1.6e-178 593.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK65553.1 - 7.5e-08 31.5 0.0 1.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 GAK65553.1 - 0.21 10.7 0.0 3.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Cu_amine_oxid PF01179.15 GAK65554.1 - 2e-160 534.0 0.3 2.4e-160 533.8 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAK65554.1 - 6.3e-15 55.0 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAK65554.1 - 9.1e-06 25.6 0.1 7.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Zn_clus PF00172.13 GAK65555.1 - 5e-05 23.1 10.1 8.3e-05 22.4 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain QCR10 PF09796.4 GAK65556.1 - 9.3e-23 79.6 0.5 1.3e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 GAK65556.1 - 0.04 13.6 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Gln-synt_C PF00120.19 GAK65557.1 - 1.2e-60 204.8 0.0 1.5e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 GAK65557.1 - 1.8e-18 65.8 0.0 2.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF676 PF05057.9 GAK65558.1 - 7.1e-06 25.4 0.0 1.4e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAK65558.1 - 0.011 15.5 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 GAK65558.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ribosomal_L3 PF00297.17 GAK65559.1 - 1.1e-32 113.4 2.5 2.8e-32 112.1 1.7 1.6 1 1 0 1 1 1 1 Ribosomal protein L3 Pam16 PF03656.8 GAK65560.1 - 1e-18 67.3 0.5 3.3e-17 62.4 0.3 2.2 1 1 0 1 1 1 1 Pam16 tRNA-synt_1g PF09334.6 GAK65561.1 - 1.2e-143 478.5 0.0 1.6e-143 478.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAK65561.1 - 2.6e-08 32.3 0.2 0.00032 18.8 0.0 3.9 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAK65561.1 - 0.00048 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA IncA PF04156.9 GAK65561.1 - 1 8.9 6.6 1.5 8.3 4.6 1.3 1 0 0 1 1 1 0 IncA protein DZR PF12773.2 GAK65561.1 - 1.1 9.1 10.1 6.6 6.6 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 GAK65561.1 - 1.9 8.1 5.9 4.2 7.1 0.5 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family F-box-like PF12937.2 GAK65562.1 - 0.029 14.0 0.4 0.056 13.1 0.2 1.5 1 0 0 1 1 1 0 F-box-like Ribosomal_L14 PF00238.14 GAK65563.1 - 2e-30 105.0 0.0 6.6e-30 103.3 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e F-box-like PF12937.2 GAK65564.1 - 0.01 15.5 0.3 0.032 13.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like zf-C2H2_4 PF13894.1 GAK65566.1 - 0.0046 17.1 14.6 0.026 14.8 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAK65566.1 - 0.11 12.8 2.4 0.68 10.3 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 GAK65566.1 - 1.2 9.5 16.8 0.23 11.8 0.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type OTCace PF00185.19 GAK65567.1 - 7.2e-42 142.9 0.0 1.2e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 GAK65567.1 - 5.6e-40 136.2 0.0 9.8e-40 135.4 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Aminotran_1_2 PF00155.16 GAK65567.1 - 7.4e-17 61.3 0.0 1.1e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II BAR_2 PF10455.4 GAK65568.1 - 8.6e-46 156.1 0.6 1.4e-45 155.4 0.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 GAK65568.1 - 3e-20 72.7 5.1 5.5e-16 58.7 1.8 2.1 2 0 0 2 2 2 2 BAR domain Telethonin PF09470.5 GAK65568.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Telethonin protein tRNA_NucTran2_2 PF13735.1 GAK65568.1 - 0.017 14.9 1.8 0.062 13.1 1.3 2.0 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Seryl_tRNA_N PF02403.17 GAK65568.1 - 0.033 14.2 4.8 18 5.4 0.0 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Phasin PF05597.6 GAK65568.1 - 0.058 13.1 3.3 0.27 11.0 0.0 3.0 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Uds1 PF15456.1 GAK65568.1 - 0.12 12.3 7.6 0.42 10.6 0.0 2.8 2 1 0 2 2 2 0 Up-regulated During Septation DUF16 PF01519.11 GAK65568.1 - 0.18 12.0 1.8 1.7 8.9 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF16 Atg14 PF10186.4 GAK65568.1 - 0.72 8.7 4.1 0.61 8.9 1.0 2.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 GAK65568.1 - 1 8.5 10.2 3.9 6.6 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spectrin PF00435.16 GAK65568.1 - 1.8 8.8 7.1 2.4 8.5 0.2 3.0 2 2 0 2 2 2 0 Spectrin repeat TPR_MLP1_2 PF07926.7 GAK65568.1 - 3 7.5 11.0 3.5 7.3 5.5 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 GAK65568.1 - 6.7 6.5 13.0 16 5.4 0.2 4.1 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding FliX PF10768.4 GAK65569.1 - 0.065 13.4 0.5 0.065 13.4 0.4 2.0 2 0 0 2 2 2 0 Class II flagellar assembly regulator DUF4451 PF14616.1 GAK65570.1 - 2.9e-30 104.5 0.8 4.7e-30 103.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) CMS1 PF14617.1 GAK65571.1 - 3.2e-52 177.1 6.7 1.8e-25 89.4 0.0 2.2 1 1 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DUF601 PF04642.7 GAK65571.1 - 0.0011 18.4 5.4 0.0011 18.4 3.8 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF601 GvpL_GvpF PF06386.6 GAK65571.1 - 0.33 10.4 4.0 0.54 9.8 2.8 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Med19 PF10278.4 GAK65571.1 - 0.84 9.2 9.1 0.52 9.9 3.8 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Apc15p PF05841.6 GAK65571.1 - 6 7.6 8.6 3.1 8.5 3.3 2.2 2 1 0 2 2 2 0 Apc15p protein ING PF12998.2 GAK65572.1 - 3.9e-10 39.9 0.4 5.2e-10 39.5 0.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 GAK65572.1 - 8.1e-09 35.0 7.2 1.2e-08 34.4 5.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAK65572.1 - 0.036 13.3 2.2 0.064 12.5 1.5 1.4 1 0 0 1 1 1 0 PHD-finger Med4 PF10018.4 GAK65572.1 - 0.051 12.9 0.1 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CPSase_L_D2 PF02786.12 GAK65573.1 - 4.3e-113 375.7 0.1 8.7e-83 276.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 GAK65573.1 - 3.2e-44 150.0 0.0 6.9e-44 148.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.17 GAK65573.1 - 5.1e-44 148.9 0.0 1.1e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 GAK65573.1 - 5.5e-43 146.6 0.0 1.8e-42 144.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 GAK65573.1 - 1.5e-42 144.1 0.0 9.6e-21 73.9 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 GAK65573.1 - 3.9e-42 142.8 0.2 8.8e-42 141.7 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 GAK65573.1 - 2.5e-36 125.1 0.2 4.6e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 GAK65573.1 - 1.1e-34 119.5 0.0 2.5e-34 118.4 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 GAK65573.1 - 4.3e-23 81.5 0.1 8.3e-12 44.4 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAK65573.1 - 2.7e-17 62.6 0.0 3.6e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAK65573.1 - 3.1e-15 56.1 0.0 2.3e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 GAK65573.1 - 3.8e-10 39.5 0.0 1.4e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.8 GAK65573.1 - 3.9e-07 29.7 0.1 1.3e-05 24.7 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 GAK65573.1 - 1.7e-05 24.7 0.1 0.088 12.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 GAK65573.1 - 0.00099 18.7 0.0 0.075 12.5 0.0 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CRAL_TRIO PF00650.15 GAK65574.1 - 5.8e-24 84.3 0.0 8e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAK65574.1 - 1.6e-06 28.1 0.1 3.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NADHdh_A3 PF14987.1 GAK65575.1 - 0.0023 17.8 0.3 0.0028 17.5 0.2 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 ADH_zinc_N PF00107.21 GAK65577.1 - 3.1e-24 84.9 0.0 6.3e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK65577.1 - 3e-05 24.8 0.0 0.0012 19.6 0.0 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAK65577.1 - 0.083 12.4 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PNP_UDP_1 PF01048.15 GAK65578.1 - 4.1e-23 81.5 0.1 5.6e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Band_7 PF01145.20 GAK65579.1 - 2.8e-24 85.9 4.8 7.2e-24 84.6 3.1 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family tRNA-synt_2b PF00587.20 GAK65580.1 - 1.8e-21 76.4 0.0 1.2e-20 73.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FLILHELTA PF10306.4 GAK65580.1 - 1.7e-20 72.8 0.0 4.3e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF4618 PF15397.1 GAK65580.1 - 0.0053 16.1 1.8 0.0053 16.1 1.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) DUF1279 PF06916.8 GAK65580.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DUF342 PF03961.8 GAK65580.1 - 0.4 9.0 1.6 0.71 8.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 GAK65580.1 - 3.4 6.5 6.3 6.3 5.6 4.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DNA_topoisoIV PF00521.15 GAK65581.1 - 2e-128 428.8 0.0 3.8e-128 427.9 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 GAK65581.1 - 2e-35 121.5 1.6 4.8e-35 120.3 1.1 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 GAK65581.1 - 1.7e-14 53.5 0.0 6.4e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 GAK65581.1 - 2e-09 37.1 0.0 4.6e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RabGAP-TBC PF00566.13 GAK65582.1 - 4.9e-58 196.1 0.3 7.5e-58 195.5 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Asn_synthase PF00733.16 GAK65583.1 - 7.2e-50 169.8 0.1 1.2e-49 169.1 0.1 1.4 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 GAK65583.1 - 1.8e-11 43.8 0.0 4.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAK65583.1 - 8.3e-09 35.5 0.0 1.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Methyltransf_26 PF13659.1 GAK65583.1 - 0.16 12.0 1.2 0.57 10.2 0.8 2.2 1 1 0 1 1 1 0 Methyltransferase domain Chs3p PF12271.3 GAK65584.1 - 6.4e-113 376.5 17.0 7.4e-113 376.3 11.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit WD40 PF00400.27 GAK65585.1 - 7.2e-47 155.6 10.5 8.7e-10 38.1 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 GAK65585.1 - 5.4e-09 34.7 3.1 0.00061 18.0 0.0 4.4 3 2 1 4 4 4 3 Nucleoporin Nup120/160 DUF869 PF05911.6 GAK65585.1 - 0.006 14.8 0.1 0.0085 14.3 0.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 GAK65585.1 - 0.066 13.0 5.1 0.14 11.9 3.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med3 PF11593.3 GAK65586.1 - 0.12 11.5 10.1 0.15 11.2 7.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_22 PF13401.1 GAK65587.1 - 8.2e-17 61.5 3.9 1.4e-16 60.8 0.0 3.0 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 GAK65587.1 - 2.5e-09 37.4 0.0 6.4e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAK65587.1 - 7.8e-09 35.4 0.9 2.3e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAK65587.1 - 6.9e-08 32.6 2.1 6.9e-08 32.6 1.5 3.7 3 2 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 GAK65587.1 - 0.0009 18.1 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 GAK65587.1 - 0.0021 17.8 0.0 0.0071 16.0 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 GAK65587.1 - 0.017 15.0 2.7 0.028 14.3 0.5 2.7 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 GAK65587.1 - 0.12 11.3 0.0 0.34 9.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KH_1 PF00013.24 GAK65588.1 - 4.5e-05 22.9 0.6 9.4e-05 21.9 0.4 1.5 1 0 0 1 1 1 1 KH domain RRM_1 PF00076.17 GAK65589.1 - 5.5e-76 250.1 0.4 1.3e-18 66.3 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65589.1 - 1.1e-53 179.1 0.2 5.8e-15 55.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK65589.1 - 1.4e-45 152.9 0.1 2.6e-11 43.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 GAK65589.1 - 3.9e-29 100.1 1.6 1.5e-28 98.2 1.0 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain CbiG_mid PF11761.3 GAK65589.1 - 0.0019 18.4 0.0 6.7 7.0 0.0 3.4 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 GAK65589.1 - 0.0044 16.7 2.5 0.55 10.0 0.2 3.5 4 0 0 4 4 4 1 Limkain b1 RRM_3 PF08777.6 GAK65589.1 - 0.01 15.6 3.6 1.3 8.9 1.0 3.4 4 0 0 4 4 4 0 RNA binding motif OB_RNB PF08206.6 GAK65589.1 - 0.03 13.8 0.7 13 5.3 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain GrpE PF01025.14 GAK65590.1 - 5.7e-43 146.3 0.1 7.2e-43 145.9 0.1 1.2 1 0 0 1 1 1 1 GrpE BicD PF09730.4 GAK65590.1 - 0.0044 15.4 0.5 0.0051 15.2 0.4 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF4201 PF13870.1 GAK65590.1 - 0.032 13.6 1.0 0.044 13.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Bap31 PF05529.7 GAK65590.1 - 2 7.8 5.6 2.8 7.3 3.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Choline_transpo PF04515.7 GAK65591.1 - 7.7e-35 120.1 13.7 1.2e-22 80.0 0.1 2.5 3 0 0 3 3 3 2 Plasma-membrane choline transporter PCI PF01399.22 GAK65592.1 - 1.8e-05 24.9 0.1 3.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain COG2 PF06148.6 GAK65592.1 - 0.014 15.2 1.4 0.027 14.3 1.0 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2669 PF10876.3 GAK65592.1 - 0.061 13.0 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2669) ParB PF08775.5 GAK65592.1 - 0.19 12.0 1.5 0.34 11.2 1.0 1.3 1 0 0 1 1 1 0 ParB family Pkinase PF00069.20 GAK65593.1 - 2.4e-59 200.6 0.0 1.1e-58 198.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK65593.1 - 1e-27 96.8 0.0 3.6e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK65593.1 - 4.6e-07 29.0 0.0 8e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK65593.1 - 0.0094 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAK65593.1 - 0.052 12.3 0.1 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Adap_comp_sub PF00928.16 GAK65594.1 - 5.5e-91 304.2 0.0 1.2e-90 303.1 0.0 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Oxysterol_BP PF01237.13 GAK65594.1 - 4e-82 275.5 0.0 8.8e-82 274.4 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein Clat_adaptor_s PF01217.15 GAK65594.1 - 1.7e-06 27.7 0.2 2.9e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PA_decarbox PF05870.6 GAK65595.1 - 2.4e-09 36.8 0.1 3.1e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Phage_lambda_P PF06992.6 GAK65595.1 - 0.024 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Replication protein P ParA PF10609.4 GAK65596.1 - 1.7e-33 114.3 0.0 3e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAK65596.1 - 4.6e-11 42.5 0.0 1.4e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAK65596.1 - 5.9e-06 26.2 0.0 5.6e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 GAK65596.1 - 6.2e-06 25.4 0.8 7.8e-05 21.8 0.2 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase zf-C4_ClpX PF06689.8 GAK65596.1 - 0.00039 19.8 0.4 0.00068 19.0 0.3 1.3 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA_26 PF13500.1 GAK65596.1 - 0.0055 16.3 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.6 GAK65596.1 - 0.0077 15.3 0.0 0.024 13.7 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ Cache_3 PF14827.1 GAK65596.1 - 0.0099 15.7 0.2 0.048 13.5 0.0 2.2 2 0 0 2 2 2 1 Sensory domain of two-component sensor kinase AAA_25 PF13481.1 GAK65596.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAK65596.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAK65596.1 - 0.073 13.2 0.1 0.38 10.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 GAK65596.1 - 0.19 11.7 0.9 3.9 7.4 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain EMP24_GP25L PF01105.19 GAK65599.1 - 1.2e-47 162.0 0.0 1.3e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Voltage_CLC PF00654.15 GAK65600.1 - 3.8e-91 305.7 28.9 5.5e-91 305.2 20.0 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel Pro_isomerase PF00160.16 GAK65600.1 - 6.3e-32 110.9 0.0 1.1e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 GAK65600.1 - 1.3e-15 56.8 0.0 2.9e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65600.1 - 6.7e-11 42.0 0.1 1.8e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.23 GAK65600.1 - 3e-08 33.3 0.1 1.2e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 CBS domain RRM_5 PF13893.1 GAK65600.1 - 7.8e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 GAK65600.1 - 0.013 14.0 27.3 0.025 13.0 18.9 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNA_pol_Rpc4 PF05132.9 GAK65601.1 - 0.17 11.9 1.3 0.23 11.4 0.9 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mem_trans PF03547.13 GAK65601.1 - 1.1 7.4 2.9 1.2 7.3 2.0 1.0 1 0 0 1 1 1 0 Membrane transport protein APC_CDC26 PF10471.4 GAK65601.1 - 1.9 9.3 6.6 2.7 8.8 4.6 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Sec3_C PF09763.4 GAK65601.1 - 2.4 6.1 5.1 2.8 5.9 3.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.4 GAK65601.1 - 4.7 5.3 6.4 5.3 5.2 4.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Linker_histone PF00538.14 GAK65602.1 - 9.2e-11 41.6 0.1 2.2e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family BatD PF13584.1 GAK65602.1 - 0.021 13.4 3.8 0.03 12.9 2.6 1.2 1 0 0 1 1 1 0 Oxygen tolerance Baculo_11_kDa PF06143.6 GAK65602.1 - 0.023 14.0 0.4 0.046 13.0 0.3 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF912 PF06024.7 GAK65602.1 - 0.026 14.5 0.4 0.071 13.1 0.2 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 GAK65602.1 - 0.026 14.8 0.3 0.059 13.7 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 GAK65602.1 - 0.043 13.5 0.3 0.066 12.9 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family SpoIIIAH PF12685.2 GAK65602.1 - 0.053 13.0 0.3 0.053 13.0 0.2 2.4 3 0 0 3 3 3 0 SpoIIIAH-like protein SP_C-Propep PF08999.5 GAK65602.1 - 0.058 12.8 1.3 0.11 12.0 0.9 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Rifin_STEVOR PF02009.11 GAK65602.1 - 0.076 12.6 8.3 0.025 14.2 3.5 1.8 1 1 1 2 2 2 0 Rifin/stevor family Herpes_gE PF02480.11 GAK65602.1 - 0.17 10.1 4.4 0.26 9.5 3.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF929 PF06053.6 GAK65602.1 - 0.24 10.4 1.2 0.38 9.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF3357 PF11837.3 GAK65602.1 - 0.56 10.0 5.6 0.5 10.2 1.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) Shisa PF13908.1 GAK65602.1 - 1.6 8.8 9.0 1.5 9.0 4.8 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator MutL_C PF08676.6 GAK65603.1 - 1.7e-09 37.4 0.2 3.5e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 MutL C terminal dimerisation domain PCI PF01399.22 GAK65607.1 - 8.3e-09 35.7 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain TIP120 PF08623.5 GAK65608.1 - 3.7e-49 166.5 3.6 9.6e-49 165.2 0.0 3.4 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 GAK65608.1 - 2.7e-15 56.4 36.2 0.00012 22.3 0.4 9.4 7 3 5 12 12 12 9 HEAT repeats HEAT_EZ PF13513.1 GAK65608.1 - 4.3e-12 46.1 42.0 0.026 14.9 0.1 12.8 11 2 4 15 15 15 6 HEAT-like repeat HEAT PF02985.17 GAK65608.1 - 1.4e-11 43.4 33.8 0.87 9.8 0.1 13.8 14 0 0 14 14 14 5 HEAT repeat Cohesin_HEAT PF12765.2 GAK65608.1 - 0.0035 17.2 0.4 0.03 14.2 0.1 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 GAK65608.1 - 0.0049 16.7 7.7 0.32 10.8 0.0 5.2 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 GAK65608.1 - 0.0092 14.9 3.2 0.26 10.2 0.1 4.2 4 2 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Ipi1_N PF12333.3 GAK65608.1 - 0.68 9.9 7.8 3.2 7.7 0.1 5.0 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation PHO4 PF01384.15 GAK65609.1 - 1.2e-114 382.3 15.9 1.4e-114 382.1 11.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.11 GAK65610.1 - 3.8e-31 108.0 42.9 4.1e-29 101.4 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BLVR PF06375.6 GAK65612.1 - 0.37 10.6 4.6 0.21 11.3 1.4 1.9 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) E1-E2_ATPase PF00122.15 GAK65613.1 - 2.3e-59 200.2 0.3 6.8e-59 198.6 0.2 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAK65613.1 - 5.9e-46 156.2 6.6 5.9e-46 156.2 4.6 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAK65613.1 - 8.2e-27 95.0 0.0 6.3e-26 92.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK65613.1 - 4e-18 65.1 0.1 1e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAK65613.1 - 5.6e-14 52.7 0.3 5.6e-13 49.4 0.1 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK65613.1 - 9.9e-08 31.3 0.3 2.1e-06 27.1 0.1 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAK65613.1 - 0.00052 19.6 0.3 0.012 15.2 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phosphodiest PF01663.17 GAK65615.1 - 9.5e-08 31.7 2.5 1.9e-07 30.7 1.7 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 GAK65615.1 - 0.021 14.2 2.5 0.035 13.4 1.7 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.18 GAK65615.1 - 0.085 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Sulfatase SUR7 PF06687.7 GAK65616.1 - 6.1e-21 74.9 4.2 8.6e-21 74.4 2.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 GAK65616.1 - 0.0046 16.6 3.9 0.0046 16.6 2.7 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction RseC_MucC PF04246.7 GAK65616.1 - 0.023 14.2 0.4 0.023 14.2 0.3 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC MscS_TM PF12794.2 GAK65616.1 - 0.13 10.8 3.0 0.23 10.0 2.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 PMP22_Claudin PF00822.15 GAK65616.1 - 0.15 11.7 3.9 0.44 10.1 2.7 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.7 GAK65616.1 - 1.6 7.9 8.4 0.091 12.0 1.9 1.7 2 0 0 2 2 2 0 Clc-like DUF4407 PF14362.1 GAK65616.1 - 3.4 6.5 8.1 5.5 5.8 5.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Amastin PF07344.6 GAK65616.1 - 3.6 7.1 8.4 0.7 9.5 2.7 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein FUSC_2 PF13515.1 GAK65616.1 - 3.9 7.3 14.0 1.3 8.9 6.8 2.1 2 1 0 2 2 2 0 Fusaric acid resistance protein-like Cyto_ox_2 PF02322.10 GAK65616.1 - 4.1 6.4 13.1 6.2 5.8 9.1 1.5 1 1 0 1 1 1 0 Cytochrome oxidase subunit II Ribosomal_S7 PF00177.16 GAK65617.1 - 1.6e-34 118.6 0.4 2.8e-34 117.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Myb_DNA-binding PF00249.26 GAK65617.1 - 4.6e-20 71.4 3.0 1.4e-11 44.2 0.2 5.5 5 1 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAK65617.1 - 1.7e-16 60.0 0.1 2.7e-07 30.5 0.0 4.3 3 1 2 5 5 5 2 Myb-like DNA-binding domain Peptidase_S10 PF00450.17 GAK65618.1 - 4.2e-98 329.2 0.0 5.7e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CN_hydrolase PF00795.17 GAK65619.1 - 5.3e-19 68.2 0.0 7.2e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LNS2 PF08235.8 GAK65620.1 - 2e-67 225.6 0.1 1.3e-53 180.7 0.0 2.7 3 0 0 3 3 3 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 GAK65620.1 - 1.7e-28 98.4 2.2 5e-19 68.0 0.0 3.1 3 0 0 3 3 3 2 lipin, N-terminal conserved region DUF4588 PF15251.1 GAK65621.1 - 2.6e-05 24.3 9.4 2.6e-05 24.3 6.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) Macoilin PF09726.4 GAK65621.1 - 1.4 7.1 5.4 1.9 6.6 3.7 1.2 1 0 0 1 1 1 0 Transmembrane protein IPP-2 PF04979.9 GAK65622.1 - 4.1e-14 52.9 4.2 5.6e-07 29.8 2.1 2.2 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Corona_nucleoca PF00937.13 GAK65622.1 - 0.071 12.0 3.3 0.11 11.4 2.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DLIC PF05783.6 GAK65623.1 - 1.4e-50 172.4 12.3 5.9e-27 94.4 0.0 6.7 4 2 3 7 7 7 6 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 GAK65623.1 - 0.001 19.1 3.2 0.0062 16.5 0.3 2.8 1 1 1 2 2 2 1 AAA ATPase domain MCM PF00493.18 GAK65623.1 - 0.0024 16.7 0.1 0.0045 15.8 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family Miro PF08477.8 GAK65623.1 - 0.0035 17.8 0.1 0.04 14.4 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 GAK65623.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK65623.1 - 0.024 14.0 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 GAK65623.1 - 0.036 13.5 0.3 0.1 12.1 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2813 PF11398.3 GAK65623.1 - 0.067 12.2 0.1 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Pkr1 PF08636.5 GAK65624.1 - 8.9e-16 57.7 2.9 1.2e-15 57.2 2.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 PRA1 PF03208.14 GAK65624.1 - 0.002 17.4 1.3 0.0023 17.2 0.9 1.1 1 0 0 1 1 1 1 PRA1 family protein UPF0154 PF03672.8 GAK65624.1 - 0.026 14.1 0.4 0.065 12.8 0.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF3329 PF11808.3 GAK65624.1 - 0.047 13.7 1.1 3.4 7.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) OAD_gamma PF04277.8 GAK65624.1 - 3.5 8.0 4.6 28 5.1 3.2 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4232 PF14016.1 GAK65627.1 - 0.36 10.4 8.3 0.92 9.1 1.1 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF4232) DUF676 PF05057.9 GAK65628.1 - 5.5e-31 107.5 0.0 2.8e-30 105.2 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAK65628.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK65628.1 - 0.00066 19.6 5.3 0.0015 18.4 3.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAK65628.1 - 0.0047 16.2 0.0 0.015 14.5 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family ABC_tran PF00005.22 GAK65629.1 - 3e-48 163.5 0.1 9.3e-24 84.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 GAK65629.1 - 3e-22 79.1 24.4 1.2e-12 47.5 2.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 GAK65629.1 - 1e-15 58.5 1.5 4.5e-06 26.8 0.0 4.3 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 GAK65629.1 - 9.6e-06 24.9 0.0 0.62 9.2 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAK65629.1 - 9.4e-05 21.8 1.7 0.0095 15.4 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 GAK65629.1 - 0.027 13.8 2.2 2.3 7.6 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 GAK65629.1 - 0.058 13.3 0.1 4.5 7.2 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAK65629.1 - 0.12 12.7 1.0 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAK65629.1 - 0.89 9.3 5.2 2.6 7.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 CN_hydrolase PF00795.17 GAK65630.1 - 5.7e-28 97.5 0.0 1e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LSM PF01423.17 GAK65632.1 - 1.9e-05 24.1 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAK65632.1 - 0.0025 17.6 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Glyco_transf_9 PF01075.12 GAK65632.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) NMO PF03060.10 GAK65633.1 - 1.1e-70 238.4 0.2 1.2e-70 238.2 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAK65633.1 - 2e-10 40.0 0.4 3.4e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAK65633.1 - 5.5e-05 22.1 0.8 8.2e-05 21.6 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 GAK65633.1 - 0.018 14.2 0.6 0.15 11.2 0.1 2.2 2 0 0 2 2 2 0 PcrB family Semialdhyde_dhC PF02774.13 GAK65635.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain AAA_18 PF13238.1 GAK65636.1 - 7.3e-21 74.8 0.0 2e-20 73.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK65636.1 - 2.6e-10 41.1 0.0 5.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAK65636.1 - 0.0047 16.8 3.0 0.0064 16.4 1.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAK65636.1 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 GAK65636.1 - 0.052 12.9 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain KTI12 PF08433.5 GAK65636.1 - 0.052 12.7 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 GAK65636.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 GAK65636.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 GAK65636.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 GAK65636.1 - 0.16 11.4 0.0 0.39 10.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF927 PF06048.6 GAK65636.1 - 0.18 11.0 0.4 0.79 8.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF927) AAA_33 PF13671.1 GAK65636.1 - 1.2 9.0 4.4 5.2 6.9 0.3 2.8 3 1 0 3 3 3 0 AAA domain Septin PF00735.13 GAK65637.1 - 4.9e-107 357.1 0.6 6.8e-107 356.6 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 GAK65637.1 - 2.2e-07 30.8 0.0 4.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK65637.1 - 0.00018 20.9 0.1 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 GAK65637.1 - 0.00067 20.4 2.6 0.002 18.9 0.1 2.5 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.18 GAK65637.1 - 0.00077 19.3 6.3 0.051 13.3 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 GAK65637.1 - 0.0011 18.1 0.4 0.0047 16.1 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAK65637.1 - 0.0015 18.9 0.3 0.0048 17.3 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 GAK65637.1 - 0.0015 18.0 0.2 0.0033 16.9 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gasdermin PF04598.7 GAK65637.1 - 0.0031 16.3 1.5 0.0043 15.8 1.0 1.1 1 0 0 1 1 1 1 Gasdermin family AIG1 PF04548.11 GAK65637.1 - 0.0038 16.3 0.0 0.0087 15.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_33 PF13671.1 GAK65637.1 - 0.0039 17.0 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAK65637.1 - 0.0048 16.8 2.1 0.046 13.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 GAK65637.1 - 0.0051 16.9 0.7 0.016 15.3 0.0 2.1 3 1 0 3 3 3 1 AAA domain IIGP PF05049.8 GAK65637.1 - 0.01 14.6 0.9 0.023 13.5 0.1 1.9 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MobB PF03205.9 GAK65637.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAK65637.1 - 0.024 14.0 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAK65637.1 - 0.03 14.6 0.4 0.11 12.8 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 GAK65637.1 - 0.066 13.1 1.7 0.076 12.9 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 GAK65637.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ras PF00071.17 GAK65637.1 - 0.075 12.4 0.3 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Ras family NACHT PF05729.7 GAK65637.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 GAK65637.1 - 0.11 12.2 0.1 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 GAK65637.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAK65637.1 - 0.13 12.5 4.9 0.21 11.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAK65637.1 - 2.7 7.7 7.3 2 8.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 TPK_B1_binding PF04265.9 GAK65638.1 - 1.6e-19 69.3 0.0 2.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 GAK65638.1 - 2.4e-19 69.1 0.0 4.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Lactamase_B_2 PF12706.2 GAK65638.1 - 1.9e-18 66.7 0.0 4.5e-18 65.5 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAK65638.1 - 5.7e-11 42.4 0.2 2.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 GAK65638.1 - 0.27 10.1 0.1 0.45 9.3 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Cortex-I_coil PF09304.5 GAK65639.1 - 2.9e-34 117.3 20.1 2.9e-34 117.3 13.9 1.9 2 0 0 2 2 2 1 Cortexillin I, coiled coil Spindle_Spc25 PF08234.7 GAK65639.1 - 8.7e-21 73.7 0.1 2.1e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Hrs_helical PF12210.3 GAK65639.1 - 0.0057 16.8 8.2 0.18 12.0 0.9 3.1 3 0 0 3 3 3 2 Hepatocyte growth factor-regulated tyrosine kinase substrate CALCOCO1 PF07888.6 GAK65639.1 - 0.0061 14.9 14.2 0.0081 14.4 9.8 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 GAK65639.1 - 0.016 13.8 12.8 0.027 13.1 8.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 GAK65639.1 - 0.69 7.6 6.4 0.94 7.2 4.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 GAK65639.1 - 0.86 9.1 20.6 0.07 12.6 7.3 2.8 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1515 PF07439.6 GAK65639.1 - 1.5 8.6 3.7 0.8 9.5 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) DUF342 PF03961.8 GAK65639.1 - 1.6 7.0 13.5 0.16 10.3 6.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 GAK65639.1 - 1.8 8.2 22.6 2.5 7.8 11.4 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 GAK65640.1 - 2.1e-56 190.9 0.0 6.8e-56 189.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK65640.1 - 2.9e-27 95.3 0.0 4.2e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK65640.1 - 6.8e-07 28.5 0.0 0.00043 19.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAK65640.1 - 0.0034 17.1 0.1 0.055 13.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAK65640.1 - 0.026 13.5 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAK65640.1 - 0.076 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-4CXXC_R1 PF10497.4 GAK65641.1 - 8.2e-16 58.0 13.1 1.6e-15 57.0 9.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 TF_Zn_Ribbon PF08271.7 GAK65641.1 - 0.43 9.9 4.6 1.4 8.2 3.2 2.0 1 0 0 1 1 1 0 TFIIB zinc-binding MAPEG PF01124.13 GAK65642.1 - 1.5e-27 95.7 2.2 1.8e-27 95.4 1.5 1.0 1 0 0 1 1 1 1 MAPEG family Ferrochelatase PF00762.14 GAK65643.1 - 7.9e-104 347.0 0.0 1e-103 346.6 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Synaptobrevin PF00957.16 GAK65643.1 - 8.6e-30 102.1 2.4 1.5e-29 101.4 1.6 1.3 1 0 0 1 1 1 1 Synaptobrevin CbiX PF01903.12 GAK65643.1 - 0.0016 18.5 0.1 2.1 8.5 0.0 2.5 2 0 0 2 2 2 2 CbiX UQ_con PF00179.21 GAK65644.1 - 8.9e-27 93.2 0.0 1.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAK65644.1 - 6.2e-05 22.7 0.0 7.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAK65644.1 - 0.0041 16.8 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 GAK65644.1 - 0.0057 16.5 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain HECT PF00632.20 GAK65645.1 - 1.6e-96 323.1 0.0 2.1e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fructosamin_kin PF03881.9 GAK65646.1 - 1.1e-61 208.4 0.0 1.3e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 GAK65646.1 - 1.2e-10 41.5 0.3 1.8e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phage_GPA PF05840.8 GAK65646.1 - 0.15 10.7 0.1 0.21 10.2 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) FH2 PF02181.18 GAK65647.1 - 0.19 10.5 13.2 0.2 10.4 2.2 2.2 1 1 0 2 2 2 0 Formin Homology 2 Domain DUF3584 PF12128.3 GAK65647.1 - 0.19 8.9 23.8 0.26 8.5 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 GAK65647.1 - 2.7 6.3 17.3 4.4 5.6 12.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 GAK65647.1 - 6.2 6.7 31.0 8.4 6.3 14.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Bromodomain PF00439.20 GAK65648.1 - 1.2e-33 114.8 0.3 3e-17 62.2 0.0 3.3 2 1 0 2 2 2 2 Bromodomain Abhydro_lipase PF04083.11 GAK65649.1 - 1.1e-15 56.6 0.0 1.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 GAK65649.1 - 1e-05 25.3 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK65649.1 - 0.031 13.8 0.1 0.083 12.4 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Rgp1 PF08737.5 GAK65650.1 - 5.6e-87 292.5 0.0 7.9e-87 292.0 0.0 1.2 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 GAK65650.1 - 0.00013 22.0 0.0 0.089 12.8 0.0 3.0 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAK65650.1 - 0.0023 17.7 0.0 0.069 12.9 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RFC1 PF08519.7 GAK65651.1 - 2.4e-53 180.0 0.0 1.6e-51 174.1 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 GAK65651.1 - 4.1e-12 46.0 0.0 7.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 GAK65651.1 - 6.4e-09 36.1 0.0 2.2e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAK65651.1 - 7e-07 28.2 0.1 5.1e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAK65651.1 - 0.00048 20.2 0.0 0.0016 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAK65651.1 - 0.001 19.1 0.1 0.003 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 GAK65651.1 - 0.0012 18.0 0.0 0.0024 16.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAK65651.1 - 0.0034 17.2 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK65651.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 GAK65651.1 - 0.0085 16.3 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK65651.1 - 0.01 16.6 1.1 0.022 15.5 0.0 2.2 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 GAK65651.1 - 0.019 14.6 0.0 0.16 11.5 0.0 2.2 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 GAK65651.1 - 0.029 13.9 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 GAK65651.1 - 0.083 12.5 0.1 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 GAK65651.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF1537 PF07005.6 GAK65652.1 - 0.0033 17.1 2.1 0.0033 17.1 1.5 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 PUF PF00806.14 GAK65653.1 - 3.3e-64 208.9 8.2 7e-09 34.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Cupin_2 PF07883.6 GAK65654.1 - 1.4e-05 24.5 0.0 2.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Cupin domain DUF1498 PF07385.7 GAK65654.1 - 0.026 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) SUA5 PF03481.8 GAK65654.1 - 0.074 13.1 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding AraC_binding PF02311.14 GAK65654.1 - 0.13 11.9 0.1 0.35 10.5 0.1 1.7 1 1 0 1 1 1 0 AraC-like ligand binding domain FMO-like PF00743.14 GAK65655.1 - 7.4e-45 153.1 0.0 4.8e-44 150.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAK65655.1 - 3.5e-24 86.0 0.1 9.3e-24 84.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAK65655.1 - 1.4e-15 57.7 0.0 1.2e-12 48.1 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK65655.1 - 1.9e-10 40.7 0.1 1.4e-06 28.2 0.1 3.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAK65655.1 - 2.3e-10 40.3 0.0 5.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK65655.1 - 5.7e-10 38.6 0.1 8.3e-08 31.5 0.0 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAK65655.1 - 4.4e-08 33.4 0.2 0.0006 20.1 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAK65655.1 - 3.5e-07 29.6 0.0 0.0029 16.7 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 GAK65655.1 - 6e-07 28.6 0.0 7.1e-06 25.1 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 GAK65655.1 - 6.5e-06 24.8 0.1 0.018 13.5 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 GAK65655.1 - 0.00043 19.4 0.0 0.0011 18.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_10 PF13460.1 GAK65655.1 - 0.00054 20.0 0.6 0.51 10.3 0.0 3.5 4 0 0 4 4 4 1 NADH(P)-binding GIDA PF01134.17 GAK65655.1 - 0.00088 18.2 0.5 0.7 8.6 0.0 3.2 3 1 1 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 GAK65655.1 - 0.0014 18.8 0.0 2.4 8.4 0.0 2.7 3 1 0 3 3 2 2 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 GAK65655.1 - 0.0032 16.8 0.1 0.013 14.9 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 GAK65655.1 - 0.0036 17.4 0.0 0.43 10.6 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 GAK65655.1 - 0.0037 16.2 0.0 1.2 7.9 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAK65655.1 - 0.035 12.9 0.1 0.11 11.2 0.1 1.9 1 1 1 2 2 2 0 FAD binding domain TrkA_N PF02254.13 GAK65655.1 - 0.061 13.3 0.1 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 GAK65655.1 - 0.069 12.8 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAK65655.1 - 0.073 12.1 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 GAK65655.1 - 0.08 12.6 0.5 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FF PF01846.14 GAK65656.1 - 4.3e-28 97.0 8.6 1.1e-07 31.6 0.2 6.6 5 2 0 5 5 5 5 FF domain WW PF00397.21 GAK65656.1 - 6.2e-09 35.5 7.1 1.3e-07 31.2 0.9 2.5 2 0 0 2 2 2 2 WW domain DUF3752 PF12572.3 GAK65657.1 - 4.6e-15 56.0 46.2 5.8e-12 45.9 10.3 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3752) Acetate_kinase PF00871.12 GAK65658.1 - 1.2e-72 244.6 0.0 1.4e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Polyketide_cyc2 PF10604.4 GAK65658.1 - 2.5e-11 43.9 0.0 1.2e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport XFP_N PF09364.5 GAK65659.1 - 2.9e-127 424.3 0.0 4.5e-127 423.7 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 GAK65659.1 - 1.6e-56 190.7 0.0 3.3e-56 189.7 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 GAK65659.1 - 3.4e-53 180.0 0.0 6.9e-53 179.0 0.0 1.5 1 1 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 GAK65659.1 - 0.017 14.7 0.2 0.039 13.5 0.1 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.19 GAK65659.1 - 0.07 12.6 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Pyr_redox_3 PF13738.1 GAK65660.1 - 9.3e-28 97.6 0.1 1.1e-26 94.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAK65660.1 - 2.8e-13 49.5 2.0 2.3e-10 39.9 0.3 3.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAK65660.1 - 8.7e-11 41.6 0.0 1.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAK65660.1 - 8e-10 37.5 0.1 3e-09 35.6 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 GAK65660.1 - 9.2e-06 25.5 0.0 0.012 15.4 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAK65660.1 - 1.6e-05 24.9 0.0 0.004 17.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK65660.1 - 8.5e-05 21.6 1.0 0.0038 16.1 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAK65660.1 - 0.00017 20.8 0.0 0.0026 16.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 GAK65660.1 - 0.00022 20.1 0.4 0.49 9.1 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAK65660.1 - 0.00045 19.1 0.0 0.032 13.0 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAK65660.1 - 0.0008 18.4 0.1 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 GAK65660.1 - 0.0011 18.1 0.1 0.0026 16.9 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 GAK65660.1 - 0.045 14.1 0.0 7.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK65660.1 - 0.076 11.4 0.6 0.17 10.3 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein Amidase PF01425.16 GAK65662.1 - 1.7e-78 264.4 0.0 1e-69 235.5 0.0 2.1 2 0 0 2 2 2 2 Amidase PBP1_TM PF14812.1 GAK65666.1 - 9 6.6 8.7 4.8 7.5 1.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOC3p PF07540.6 GAK65667.1 - 1.3e-21 76.6 0.0 2.8e-20 72.3 0.0 2.8 1 1 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 GAK65667.1 - 5.8e-18 64.8 0.3 2e-17 63.1 0.2 2.0 1 0 0 1 1 1 1 CBF/Mak21 family DnaJ PF00226.26 GAK65668.1 - 1.1e-14 53.8 0.0 2.7e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 GAK65669.1 - 4.3e-13 49.0 0.5 9.7e-13 47.8 0.4 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 GAK65669.1 - 2.8e-11 43.3 14.8 2.8e-11 43.3 10.3 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 GAK65669.1 - 0.00069 19.3 0.1 0.00069 19.3 0.1 2.3 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF973 PF06157.6 GAK65670.1 - 0.15 11.0 2.7 0.1 11.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Tetraspannin PF00335.15 GAK65670.1 - 0.18 11.0 3.6 8.1 5.6 1.2 2.2 2 0 0 2 2 2 0 Tetraspanin family TrbL PF04610.9 GAK65670.1 - 1 9.0 6.2 1.2 8.8 0.3 2.7 3 0 0 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein Abhydrolase_1 PF00561.15 GAK65671.1 - 9.9e-26 90.6 0.4 3.1e-13 49.8 0.1 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold SMC_N PF02463.14 GAK65672.1 - 6.9e-20 71.2 0.0 1.6e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAK65672.1 - 1.6e-17 64.5 10.1 1.6e-17 64.5 7.0 4.1 4 1 0 4 4 4 2 AAA domain AAA_21 PF13304.1 GAK65672.1 - 2.9e-08 34.0 0.1 0.0014 18.7 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAK65672.1 - 0.0016 17.9 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 GAK65672.1 - 0.0037 16.3 0.0 0.022 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.1 GAK65672.1 - 0.25 9.7 46.0 0.38 9.1 0.0 4.9 3 2 1 4 4 4 0 AAA domain AAA_17 PF13207.1 GAK65672.1 - 1.4 9.7 0.0 1.4 9.7 0.0 3.6 3 2 0 3 3 3 0 AAA domain Seadorna_VP6 PF07407.6 GAK65672.1 - 6.3 5.4 6.3 11 4.6 4.3 1.3 1 0 0 1 1 1 0 Seadornavirus VP6 protein Glyco_hydro_10 PF00331.15 GAK65673.1 - 7e-103 344.0 0.0 8e-103 343.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 GAK65673.1 - 0.025 14.1 0.1 0.093 12.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) Cellulase-like PF12876.2 GAK65673.1 - 0.032 14.6 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like MaoC_dehydratas PF01575.14 GAK65674.1 - 4.1e-10 39.1 0.0 1.3e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain p450 PF00067.17 GAK65675.1 - 9.3e-61 205.7 0.0 1.3e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 GAK65676.1 - 3.9e-05 23.2 0.7 0.00011 21.8 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK65676.1 - 0.00044 19.8 0.5 0.0044 16.6 0.2 2.8 3 0 0 3 3 3 1 F-box domain LIP PF03583.9 GAK65678.1 - 1.9e-56 191.3 0.1 2.8e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 GAK65678.1 - 0.055 12.6 0.1 4.1 6.5 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family Cutinase PF01083.17 GAK65678.1 - 0.082 12.6 0.3 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Cutinase Fungal_trans_2 PF11951.3 GAK65679.1 - 5.1e-11 41.7 1.6 1.6e-10 40.2 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65679.1 - 1.5e-07 31.2 9.8 3.4e-07 30.0 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 GAK65681.1 - 7.3e-43 146.8 0.0 1e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAK65681.1 - 0.048 12.9 0.1 0.096 11.9 0.1 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase peroxidase PF00141.18 GAK65682.1 - 1.3e-84 283.3 0.0 9.5e-45 152.8 0.0 2.2 2 0 0 2 2 2 2 Peroxidase AA_permease_2 PF13520.1 GAK65683.1 - 6.5e-45 153.4 44.7 8.4e-45 153.0 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAK65683.1 - 2.5e-16 59.1 40.7 2.5e-16 59.1 28.2 2.0 2 0 0 2 2 2 2 Amino acid permease Cu_amine_oxid PF01179.15 GAK65684.1 - 5.3e-160 532.6 0.0 6.4e-160 532.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 GAK65684.1 - 1.8e-07 31.1 0.2 3.7e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 GAK65684.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.7 1 1 0 1 1 1 0 Copper amine oxidase, N3 domain Fungal_trans PF04082.13 GAK65685.1 - 5.2e-17 61.5 0.4 1.1e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAK65685.1 - 9.3e-09 35.1 14.6 1.4e-05 25.1 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK65685.1 - 4.2e-07 29.8 11.6 0.0039 17.4 3.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.13 GAK65685.1 - 1e-06 28.5 8.9 1e-06 28.5 6.2 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 GAK65685.1 - 0.0048 16.7 18.5 0.012 15.4 0.4 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 GAK65685.1 - 0.0056 16.8 3.2 0.42 10.8 1.1 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAK65685.1 - 0.0067 16.5 6.3 1 9.5 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 GAK65685.1 - 0.02 15.1 11.0 0.28 11.5 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double domain CENP-B_dimeris PF09026.5 GAK65685.1 - 0.23 11.7 4.2 0.16 12.2 1.3 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Aldedh PF00171.17 GAK65687.1 - 3.3e-144 480.6 0.0 3.7e-144 480.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK65687.1 - 3.2e-07 29.4 0.0 1.3e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 GAK65688.1 - 9.5e-05 20.9 0.3 0.00019 19.9 0.2 1.5 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4336 PF14234.1 GAK65688.1 - 0.062 12.4 0.3 0.14 11.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) LigB PF02900.13 GAK65689.1 - 5.2e-27 94.5 0.0 5.8e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Creatininase PF02633.9 GAK65689.1 - 0.049 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Creatinine amidohydrolase Peptidase_S15 PF02129.13 GAK65691.1 - 6.1e-38 130.7 0.6 9.5e-38 130.1 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAK65691.1 - 2.2e-27 96.3 0.2 3.4e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 GAK65691.1 - 7e-05 22.6 0.1 0.00023 20.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK65691.1 - 0.00045 20.1 0.3 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 GAK65692.1 - 1.8e-12 47.0 0.5 6e-11 42.0 0.3 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAK65692.1 - 8.3e-06 25.7 0.0 1.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK65692.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK65692.1 - 0.016 14.1 1.1 0.045 12.6 0.2 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK65692.1 - 0.026 14.2 0.1 0.41 10.4 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAK65692.1 - 0.069 13.5 0.3 0.25 11.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAK65692.1 - 0.081 11.7 0.5 0.17 10.7 0.4 1.6 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 GAK65692.1 - 0.29 9.7 0.5 7.7 5.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_1 PF00232.13 GAK65693.1 - 6.6e-105 350.9 0.0 1e-104 350.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.13 GAK65693.1 - 0.0063 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAA_hydrolase PF01557.13 GAK65694.1 - 8.3e-40 136.5 0.0 1.1e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAK65694.1 - 6.5e-24 83.9 0.2 1.2e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.11 GAK65695.1 - 2.7e-23 82.2 33.2 5.3e-12 45.1 6.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAK65695.1 - 2.7e-06 26.4 0.2 4.8e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65695.1 - 0.0037 17.1 6.4 0.011 15.6 4.4 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_3 PF01764.20 GAK65695.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) AA_permease_2 PF13520.1 GAK65696.1 - 1.7e-60 204.7 45.4 2.2e-60 204.4 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAK65696.1 - 2.3e-21 75.7 40.6 3.1e-21 75.2 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 GAK65696.1 - 0.22 11.3 0.0 0.22 11.3 0.0 4.1 4 0 0 4 4 4 0 Gram positive anchor TFIIF_beta PF02270.10 GAK65697.1 - 2.2e-56 191.6 0.0 3.3e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF3245 PF11595.3 GAK65697.1 - 2.6 8.3 13.9 2.2 8.5 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Ribonuclease_3 PF00636.21 GAK65698.1 - 3.3e-09 37.1 0.0 6.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 GAK65698.1 - 6.2e-07 29.9 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 GAK65698.1 - 2.2e-06 27.6 0.0 0.036 14.0 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease-III-like HTH_Tnp_1 PF01527.15 GAK65698.1 - 0.053 13.4 0.1 8.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Transposase WD40 PF00400.27 GAK65699.1 - 7.4e-50 165.1 8.8 1.5e-11 43.6 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat DUF4078 PF13300.1 GAK65699.1 - 1.4e-10 41.1 4.3 1.4e-10 41.1 3.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) DUF3312 PF11768.3 GAK65699.1 - 0.026 12.7 0.0 0.043 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 GAK65699.1 - 0.095 11.4 0.0 8 5.0 0.0 3.3 1 1 0 2 2 2 0 Nup133 N terminal like VID27 PF08553.5 GAK65699.1 - 0.18 10.0 0.0 0.48 8.5 0.0 1.6 2 0 0 2 2 2 0 VID27 cytoplasmic protein HTH_9 PF08221.6 GAK65700.1 - 1.7e-16 59.8 0.7 5.8e-08 32.5 0.0 5.4 5 0 0 5 5 5 4 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 GAK65700.1 - 1.7e-15 57.2 0.1 4.3e-14 52.6 0.2 2.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 GAK65700.1 - 1.5e-05 24.4 0.3 6.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 TFIIE alpha subunit TruB_N PF01509.13 GAK65701.1 - 1.6e-38 132.1 0.0 1.2e-37 129.3 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Abhydrolase_6 PF12697.2 GAK65702.1 - 2.4e-19 70.1 0.0 3.5e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK65702.1 - 7.6e-16 58.1 0.0 1.3e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAK65702.1 - 5e-08 32.6 0.0 2.2e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 GAK65702.1 - 1.5e-06 27.9 0.1 0.00042 19.9 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAK65702.1 - 1.7e-05 24.5 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 GAK65702.1 - 0.0031 16.5 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 GAK65702.1 - 0.0083 15.4 0.1 0.056 12.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 GAK65702.1 - 0.048 13.2 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 GAK65702.1 - 0.048 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 GAK65702.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DcpS_C PF11969.3 GAK65703.1 - 6e-19 68.3 0.0 1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 GAK65703.1 - 8.1e-07 29.5 3.1 7.4e-06 26.4 2.1 2.0 1 1 0 1 1 1 1 HIT domain Methyltransf_23 PF13489.1 GAK65704.1 - 1e-21 77.2 0.0 1.8e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK65704.1 - 1e-18 67.6 0.0 1.8e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK65704.1 - 1.8e-14 53.6 0.0 4.8e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK65704.1 - 6e-13 49.1 0.0 1.6e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK65704.1 - 4.5e-11 43.3 0.0 8.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK65704.1 - 2.8e-07 30.5 0.1 8.6e-07 28.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK65704.1 - 3.1e-07 30.6 0.0 5.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAK65704.1 - 7.9e-05 21.4 0.0 0.00016 20.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 GAK65704.1 - 0.00016 20.8 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 GAK65704.1 - 0.00018 20.6 0.0 0.00058 19.0 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 GAK65704.1 - 0.0012 18.2 0.0 0.0052 16.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 GAK65704.1 - 0.0015 17.9 0.0 0.0047 16.3 0.0 1.6 1 1 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 GAK65704.1 - 0.0037 16.4 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 GAK65704.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mpp10 PF04006.7 GAK65705.1 - 1.2e-84 284.7 142.7 4.2e-78 263.2 37.1 3.9 1 1 0 3 3 3 3 Mpp10 protein RinB PF06116.7 GAK65705.1 - 0.42 10.2 3.4 1.8 8.2 2.4 2.1 1 0 0 1 1 1 0 Transcriptional activator RinB DENN PF02141.16 GAK65706.1 - 6.7e-20 71.5 0.0 1.2e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Methyltransf_16 PF10294.4 GAK65706.1 - 5.2e-12 45.5 0.0 9.4e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAK65706.1 - 0.0031 18.0 0.1 0.0031 18.0 0.0 3.1 4 1 0 4 4 4 1 Methyltransferase domain UPF0242 PF06785.6 GAK65706.1 - 0.008 14.9 5.0 0.013 14.2 3.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) FlxA PF14282.1 GAK65706.1 - 0.016 15.1 14.2 0.36 10.7 4.3 2.8 2 0 0 2 2 2 0 FlxA-like protein tRNA-synt_1c PF00749.16 GAK65706.1 - 0.053 12.1 1.1 0.1 11.2 0.7 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Methyltransf_23 PF13489.1 GAK65706.1 - 0.069 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain IFT57 PF10498.4 GAK65706.1 - 0.28 9.8 12.0 0.72 8.5 3.7 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TMF_TATA_bd PF12325.3 GAK65706.1 - 0.46 10.2 19.2 0.021 14.5 5.7 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.14 GAK65706.1 - 4.5 4.8 23.4 0.2 9.3 11.0 2.0 2 0 0 2 2 2 0 Myosin tail GAS PF13851.1 GAK65706.1 - 7.9 5.6 12.4 1.3 8.1 4.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 GAK65706.1 - 8.4 6.2 7.3 3.3 7.5 0.3 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ArfGap PF01412.13 GAK65709.1 - 5e-41 139.1 2.1 6.1e-41 138.8 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf SARA PF11409.3 GAK65709.1 - 0.045 13.6 0.8 0.045 13.6 0.6 3.4 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) SUI1 PF01253.17 GAK65712.1 - 1.1e-12 47.5 0.1 2.7e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 TnpV PF14198.1 GAK65712.1 - 0.00076 19.3 0.3 0.0011 18.8 0.2 1.2 1 0 0 1 1 1 1 Transposon-encoded protein TnpV SPATIAL PF15256.1 GAK65712.1 - 0.05 13.6 0.5 0.076 13.0 0.4 1.3 1 0 0 1 1 1 0 SPATIAL DUF1771 PF08590.5 GAK65713.1 - 2.4e-24 85.1 7.2 2.4e-23 81.9 5.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAK65713.1 - 4.5e-15 55.6 0.3 1e-14 54.4 0.2 1.7 1 0 0 1 1 1 1 Smr domain Peripla_BP_2 PF01497.13 GAK65713.1 - 0.032 13.3 0.2 0.051 12.7 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein HJURP_C PF12347.3 GAK65713.1 - 0.032 13.8 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Mg_trans_NIPA PF05653.9 GAK65714.1 - 9.7e-28 96.9 6.3 7.1e-14 51.4 1.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Mon1 PF03164.9 GAK65715.1 - 1.1e-76 258.1 0.0 8.6e-52 176.1 0.0 3.2 3 0 0 3 3 3 3 Trafficking protein Mon1 DUF77 PF01910.12 GAK65716.1 - 1.8e-25 88.4 0.0 2.4e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 GAK65716.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family MutS_V PF00488.16 GAK65717.1 - 4.2e-93 311.0 0.0 6.4e-93 310.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAK65717.1 - 4e-36 124.7 4.3 8.4e-36 123.6 0.6 2.3 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 GAK65717.1 - 2.7e-17 63.1 0.1 1.2e-16 61.0 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 GAK65717.1 - 8.1e-15 54.7 3.4 1.3e-14 54.1 0.3 2.7 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 GAK65717.1 - 6.2e-12 45.5 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain I zf-ZPR1 PF03367.8 GAK65717.1 - 0.013 14.6 0.1 0.11 11.6 0.0 2.6 4 0 0 4 4 4 0 ZPR1 zinc-finger domain Ribonuclease_T2 PF00445.13 GAK65718.1 - 1.9e-23 83.0 0.0 4.2e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease T2 family MutS_V PF00488.16 GAK65719.1 - 1.9e-26 92.9 0.0 2.3e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 MutS domain V Peptidase_S8 PF00082.17 GAK65721.1 - 6.1e-50 169.9 0.0 1.3e-49 168.9 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 GAK65721.1 - 1.6e-15 57.4 0.1 5.5e-14 52.5 0.1 2.7 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 GAK65721.1 - 1.8e-09 37.2 0.2 6.7e-09 35.3 0.1 2.2 1 1 0 1 1 1 1 PA domain BCIP PF13862.1 GAK65722.1 - 2.6e-56 190.2 0.0 3.2e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Mpv17_PMP22 PF04117.7 GAK65724.1 - 9.5e-23 79.6 0.2 1.5e-22 78.9 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family HIG_1_N PF04588.8 GAK65724.1 - 1.7 8.4 7.2 7.9 6.3 0.4 3.0 2 1 1 3 3 3 0 Hypoxia induced protein conserved region EVE PF01878.13 GAK65725.1 - 6e-45 152.7 0.0 1.1e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 EVE domain Ribosomal_S11 PF00411.14 GAK65726.1 - 3.5e-38 130.1 0.8 5.2e-38 129.6 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L38e PF01781.13 GAK65727.1 - 7e-33 112.1 1.4 8.5e-33 111.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family E6 PF00518.12 GAK65727.1 - 0.021 15.1 0.1 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Early Protein (E6) GPI-anchored PF10342.4 GAK65728.1 - 0.027 14.9 0.1 0.069 13.6 0.0 1.8 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family C2 PF00168.25 GAK65729.1 - 4.3e-22 77.7 0.0 2.5e-16 59.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain PITH PF06201.8 GAK65730.1 - 1.7e-38 131.7 0.0 2.2e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain HMG-CoA_red PF00368.13 GAK65731.1 - 9.2e-162 537.9 5.5 1.3e-161 537.4 3.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 GAK65731.1 - 9.1e-17 60.9 2.6 4.9e-08 32.5 0.1 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 GAK65731.1 - 1.7e-06 26.2 6.7 0.0015 16.5 0.0 2.6 3 0 0 3 3 3 2 Patched family HPIH PF13323.1 GAK65731.1 - 0.0064 16.1 0.3 0.019 14.6 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain with HPIH motif CLU PF13236.1 GAK65732.1 - 1.5e-74 250.1 0.0 2.4e-74 249.5 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAK65732.1 - 3.1e-43 147.6 0.0 8.2e-43 146.2 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 GAK65732.1 - 7.1e-19 67.5 3.6 1.8e-09 37.3 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAK65732.1 - 8.1e-11 41.4 9.1 0.00028 20.7 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.1 GAK65732.1 - 8.5e-05 22.6 0.0 0.00074 19.6 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term EAP30 PF04157.11 GAK65733.1 - 6.1e-52 176.0 0.0 8.1e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 GAK65733.1 - 1.4e-29 101.6 0.0 2.5e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 GAK65733.1 - 0.00033 19.6 9.6 0.035 13.2 0.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 GAK65733.1 - 0.01 15.6 4.8 1.1 9.1 0.3 2.3 2 0 0 2 2 2 2 Double zinc ribbon DUF1024 PF06260.7 GAK65733.1 - 0.012 15.7 0.2 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) Cript PF10235.4 GAK65733.1 - 0.084 13.2 0.6 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT GCC2_GCC3 PF07699.8 GAK65733.1 - 1.8 8.2 4.3 15 5.2 0.3 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 Internalin_N PF12354.3 GAK65734.1 - 0.11 12.0 0.3 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Amidohydro_3 PF07969.6 GAK65735.1 - 3.8e-55 187.7 0.2 4.5e-55 187.5 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAK65735.1 - 2.3e-10 40.1 0.1 1.3e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 GAK65735.1 - 2.2e-08 34.1 0.0 0.00024 20.8 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAK65735.1 - 1.7e-07 31.5 1.8 0.00037 20.6 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase Shisa PF13908.1 GAK65736.1 - 0.097 12.8 0.4 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tetraspannin PF00335.15 GAK65736.1 - 1.8 7.7 7.3 4.7 6.4 5.2 1.7 1 1 0 1 1 1 0 Tetraspanin family PNPOx_C PF10590.4 GAK65737.1 - 1.2e-22 79.0 0.3 2.3e-22 78.2 0.2 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 GAK65737.1 - 7e-19 67.6 0.0 1.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 GAK65737.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyt-b5 PF00173.23 GAK65738.1 - 1.4e-08 34.3 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_3 PF01494.14 GAK65739.1 - 7.1e-25 87.8 0.2 1.3e-24 86.9 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAK65739.1 - 2.7e-14 52.8 0.9 7.9e-07 28.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAK65739.1 - 1.3e-09 38.3 0.1 2.7e-05 24.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAK65739.1 - 6.8e-06 24.9 1.1 0.0025 16.4 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAK65739.1 - 1e-05 25.5 0.1 6.6e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK65739.1 - 1.8e-05 24.6 0.1 4.8e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAK65739.1 - 2.7e-05 24.3 0.2 0.0003 20.8 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK65739.1 - 0.00017 20.2 0.2 0.13 10.6 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 GAK65739.1 - 0.0007 18.5 1.2 0.02 13.7 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 GAK65739.1 - 0.0014 18.1 0.2 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAK65739.1 - 0.002 17.0 0.4 0.0047 15.8 0.3 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAK65739.1 - 0.0087 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 GAK65739.1 - 0.023 13.5 0.6 0.7 8.7 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 GAK65739.1 - 0.067 12.7 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TGS PF02824.16 GAK65740.1 - 3.6e-21 74.7 0.0 6.5e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 GAK65740.1 - 7.8e-18 64.5 0.1 2e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK65740.1 - 2.6e-09 36.5 0.1 8.9e-09 34.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAK65740.1 - 0.0097 15.7 0.4 0.38 10.5 0.0 2.5 1 1 0 2 2 2 1 Dynamin family ArgK PF03308.11 GAK65740.1 - 0.04 12.7 3.4 0.091 11.5 0.4 2.4 2 1 1 3 3 3 0 ArgK protein Aldo_ket_red PF00248.16 GAK65741.1 - 3.8e-72 242.4 0.0 4.3e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Beta-lactamase2 PF13354.1 GAK65741.1 - 0.13 11.7 0.0 0.85 9.0 0.0 2.1 2 1 0 2 2 2 0 Beta-lactamase enzyme family SCP2 PF02036.12 GAK65742.1 - 8.2e-25 87.0 2.0 9.5e-25 86.8 1.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 GAK65742.1 - 4.7e-05 23.3 0.6 6.2e-05 22.9 0.4 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Clat_adaptor_s PF01217.15 GAK65744.1 - 7.1e-55 184.6 1.0 8.4e-55 184.3 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MBOAT PF03062.14 GAK65745.1 - 6.9e-47 160.1 16.1 6.9e-47 160.1 11.2 1.9 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Claudin_2 PF13903.1 GAK65746.1 - 0.05 13.3 6.3 0.16 11.6 1.7 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1056 PF06341.6 GAK65746.1 - 3.7 7.6 8.8 0.3 11.1 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) DUF456 PF04306.8 GAK65746.1 - 9.1 6.3 12.3 1.5 8.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF456) Bot1p PF12298.3 GAK65748.1 - 9.9e-33 113.4 0.1 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 GAK65748.1 - 0.00026 20.9 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF106 PF01956.11 GAK65749.1 - 5.3e-59 198.5 0.2 7.4e-59 198.0 0.1 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 PrgI PF12666.2 GAK65749.1 - 4.6 7.4 6.3 0.53 10.4 0.1 2.2 2 1 0 2 2 2 0 PrgI family protein NPR3 PF03666.8 GAK65750.1 - 3.2e-115 385.2 9.9 6.4e-113 377.6 0.0 3.3 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S24 PF00717.18 GAK65750.1 - 0.0058 16.2 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 Peptidase S24-like NPR2 PF06218.6 GAK65750.1 - 0.026 13.2 0.1 4.9 5.7 0.0 2.7 3 0 0 3 3 3 0 Nitrogen permease regulator 2 PEMT PF04191.8 GAK65751.1 - 3.4e-53 178.2 10.3 9.3e-32 109.2 1.3 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase Mg_trans_NIPA PF05653.9 GAK65752.1 - 5e-109 363.8 14.8 7.1e-109 363.3 10.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA RRM_1 PF00076.17 GAK65752.1 - 2.1e-22 78.5 0.0 5.9e-11 41.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65752.1 - 4.2e-13 49.0 0.0 2.1e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EmrE PF13536.1 GAK65752.1 - 2.2e-07 31.0 0.1 2.2e-07 31.0 0.1 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 GAK65752.1 - 0.0011 19.0 4.6 0.0011 19.0 3.2 3.3 3 1 0 4 4 4 1 EamA-like transporter family RRM_5 PF13893.1 GAK65752.1 - 0.014 15.2 0.0 0.082 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAGE PF01454.14 GAK65753.1 - 7.3e-34 116.8 0.0 3.6e-30 104.7 0.0 2.5 2 1 0 2 2 2 2 MAGE family LRR_4 PF12799.2 GAK65754.1 - 3.8e-25 87.0 15.2 1.6e-07 30.8 2.1 5.6 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK65754.1 - 2e-17 62.6 22.0 1e-07 31.6 2.6 5.4 4 1 1 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 GAK65754.1 - 1.6e-13 48.6 17.4 0.21 11.7 0.0 8.2 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_7 PF13504.1 GAK65754.1 - 5.8e-10 37.7 18.2 0.24 11.7 0.1 8.3 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 GAK65754.1 - 3.2e-07 29.7 23.3 2.5 8.4 0.1 7.6 6 1 1 7 7 7 4 Leucine Rich repeat zf-CCCH PF00642.19 GAK65754.1 - 0.0001 21.9 6.5 0.0014 18.2 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_3 PF07725.7 GAK65754.1 - 0.0067 16.1 0.3 0.0067 16.1 0.2 2.4 3 0 0 3 3 3 1 Leucine Rich Repeat adh_short PF00106.20 GAK65755.1 - 3.7e-18 65.9 0.2 3.7e-18 65.9 0.1 2.4 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAK65755.1 - 2.7e-10 40.1 0.1 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK65755.1 - 1.3e-05 25.0 0.1 3.5e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF2018 PF09442.5 GAK65755.1 - 0.00015 22.2 0.1 0.00034 21.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2018) NAD_binding_10 PF13460.1 GAK65755.1 - 0.024 14.6 1.3 3.8 7.4 0.9 2.7 1 1 0 1 1 1 0 NADH(P)-binding MT-A70 PF05063.9 GAK65756.1 - 2.9e-49 167.0 0.0 1.3e-32 112.8 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Methyltransf_26 PF13659.1 GAK65756.1 - 0.002 18.1 0.0 0.0047 16.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 GAK65759.1 - 2.9e-47 156.9 28.0 2.2e-08 33.6 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 GAK65759.1 - 3.1e-10 39.6 0.3 8.5e-10 38.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK65759.1 - 0.00058 19.4 0.1 0.0022 17.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 GAK65759.1 - 0.0041 15.9 0.2 0.28 9.8 0.0 3.2 2 2 1 3 3 3 1 Nup133 N terminal like ADH_zinc_N PF00107.21 GAK65760.1 - 4e-12 45.7 0.1 6.4e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 GAK65760.1 - 0.00013 21.3 0.1 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Acyl-CoA_dh_2 PF08028.6 GAK65761.1 - 4e-16 59.4 3.0 6.9e-16 58.7 2.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAK65761.1 - 4.2e-08 33.7 0.5 3e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 GAK65761.1 - 0.017 15.2 1.7 0.09 12.8 1.2 2.1 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain zf-C2H2_2 PF12756.2 GAK65762.1 - 0.056 13.5 0.1 0.056 13.5 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PI-PLC-X PF00388.14 GAK65763.1 - 2e-56 189.4 0.0 3.5e-56 188.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAK65763.1 - 1.8e-38 131.1 0.0 3.5e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.1 GAK65763.1 - 7.5e-07 29.1 0.7 2.3e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_like PF09279.6 GAK65763.1 - 2.4e-06 27.4 0.1 9.3e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 GAK65763.1 - 8.5e-05 21.5 0.0 0.3 10.5 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAK65763.1 - 0.00032 20.3 0.2 0.15 12.0 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain C2 PF00168.25 GAK65763.1 - 0.0089 15.8 0.1 2.9 7.7 0.0 3.0 3 0 0 3 3 3 1 C2 domain EF-hand_10 PF14788.1 GAK65763.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 GAK65763.1 - 0.013 15.1 0.1 3.3 7.3 0.0 3.0 2 1 2 4 4 4 0 EF-hand domain pair CreD PF06123.7 GAK65763.1 - 0.39 9.1 0.6 0.68 8.4 0.4 1.3 1 0 0 1 1 1 0 Inner membrane protein CreD DPBB_1 PF03330.13 GAK65764.1 - 2.2e-07 30.7 0.1 7.2e-07 29.1 0.1 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel C6_DPF PF10170.4 GAK65764.1 - 0.086 12.8 0.4 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 Cysteine-rich domain ILVD_EDD PF00920.16 GAK65765.1 - 6.8e-201 668.2 1.6 7.8e-201 668.0 1.1 1.0 1 0 0 1 1 1 1 Dehydratase family Methyltransf_16 PF10294.4 GAK65766.1 - 2.8e-07 30.1 0.0 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 GAK65766.1 - 6.3e-05 22.6 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 GAK65766.1 - 0.0017 18.1 0.0 0.0057 16.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK65766.1 - 0.0024 18.1 0.0 0.02 15.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK65766.1 - 0.073 13.6 0.0 0.77 10.3 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAK65766.1 - 0.22 11.5 1.4 0.92 9.5 0.9 2.1 1 1 0 1 1 1 0 Methyltransferase domain GST_C_2 PF13410.1 GAK65767.1 - 1.2e-13 50.7 0.0 3.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAK65767.1 - 1e-07 32.0 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK65767.1 - 2.4e-05 24.2 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAK65767.1 - 0.0014 19.0 0.1 0.0076 16.7 0.0 2.2 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAK65767.1 - 0.0017 18.5 0.0 0.0043 17.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAK65767.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ATXN-1_C PF12547.3 GAK65767.1 - 0.28 11.1 4.8 1.9 8.5 0.0 3.0 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator RRM_1 PF00076.17 GAK65768.1 - 9.7e-08 31.5 0.2 4.1e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK65768.1 - 1.2e-07 31.4 0.0 8.4e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAK65768.1 - 0.00023 20.8 0.0 0.0006 19.5 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 GAK65768.1 - 0.00093 19.1 0.1 0.0041 17.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 GAK65768.1 - 0.013 15.1 5.4 0.024 14.3 3.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_6 PF13516.1 GAK65769.1 - 2.8e-13 48.4 19.6 0.53 10.5 0.0 10.6 11 0 0 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.2 GAK65769.1 - 2.4e-09 36.6 23.4 5e-05 22.8 0.4 7.2 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) GAT PF03127.9 GAK65769.1 - 4.4e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.28 GAK65769.1 - 0.0098 15.7 19.6 4.5 7.6 0.0 8.5 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.1 GAK65769.1 - 0.11 12.2 19.5 0.044 13.5 0.9 5.7 6 2 1 7 7 7 0 Leucine rich repeat LRR_7 PF13504.1 GAK65769.1 - 3.2 8.3 22.8 46 4.8 0.1 9.2 11 0 0 11 11 11 0 Leucine rich repeat Pal1 PF08316.6 GAK65770.1 - 1.9e-13 51.0 0.8 1.9e-13 51.0 0.6 2.5 3 0 0 3 3 3 1 Pal1 cell morphology protein HNH_3 PF13392.1 GAK65772.1 - 2.3e-09 36.4 0.3 5.2e-09 35.3 0.1 1.7 2 0 0 2 2 2 1 HNH endonuclease HNH_3 PF13392.1 GAK65773.1 - 7.5e-20 70.0 5.5 1.3e-11 43.6 0.3 2.4 2 0 0 2 2 2 2 HNH endonuclease ATG22 PF11700.3 GAK65774.1 - 1.2e-123 413.1 13.8 1.6e-123 412.7 9.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAK65774.1 - 4.9e-11 41.9 29.4 3.2e-06 26.1 4.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF4064 PF13273.1 GAK65774.1 - 1.2 9.2 12.6 1.1 9.4 2.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) LAMTOR PF15454.1 GAK65775.1 - 1.5e-06 28.4 1.1 2.3e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator zf-RING_2 PF13639.1 GAK65776.1 - 1.3e-12 47.3 7.1 2.1e-12 46.6 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAK65776.1 - 3.5e-09 36.5 2.8 8.8e-09 35.2 1.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAK65776.1 - 3.2e-08 33.5 3.6 5.6e-08 32.7 2.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAK65776.1 - 2.8e-07 30.0 4.7 4.9e-07 29.3 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK65776.1 - 6.5e-07 28.9 4.3 1.1e-06 28.2 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAK65776.1 - 3.6e-05 23.3 5.1 0.0001 21.9 3.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAK65776.1 - 0.00042 19.9 4.6 0.0013 18.4 3.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 GAK65776.1 - 0.00081 19.1 2.5 0.0015 18.2 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 GAK65776.1 - 0.0072 16.3 0.5 0.016 15.2 0.4 1.5 1 0 0 1 1 1 1 RING-like domain RINGv PF12906.2 GAK65776.1 - 0.044 13.8 4.1 0.11 12.5 2.9 1.7 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 GAK65776.1 - 0.065 12.7 3.6 0.12 11.8 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 GAK65776.1 - 0.076 12.9 4.8 0.52 10.3 3.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 GAK65776.1 - 0.12 12.3 0.4 0.12 12.3 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 GAK65776.1 - 0.17 11.5 5.2 0.7 9.5 3.7 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 GAK65776.1 - 0.7 9.4 2.9 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 GAK65776.1 - 1.4 8.5 7.0 0.36 10.4 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Acyl_transf_1 PF00698.16 GAK65777.1 - 1.4e-55 188.8 0.0 6.9e-55 186.5 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 GAK65777.1 - 6.5e-28 96.5 0.3 8.2e-27 93.0 0.0 2.5 2 0 0 2 2 2 1 MaoC like domain ketoacyl-synt PF00109.21 GAK65777.1 - 1.1e-26 93.8 0.6 2.6e-26 92.6 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF1729 PF08354.5 GAK65777.1 - 2.1e-25 88.2 0.1 5.5e-25 86.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) adh_short_C2 PF13561.1 GAK65777.1 - 1.4e-19 70.8 0.0 3.2e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 GAK65777.1 - 7.9e-16 57.9 0.8 7.9e-16 57.9 0.5 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 GAK65777.1 - 5.4e-12 45.5 0.0 1.5e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Thiolase_N PF00108.18 GAK65777.1 - 0.0017 17.4 0.0 0.0038 16.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Tenui_NS3 PF05310.7 GAK65777.1 - 1.6 8.5 0.0 3.3 7.5 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus movement protein UQ_con PF00179.21 GAK65778.1 - 1.7e-36 124.7 0.0 2.2e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Astro_capsid_p PF12226.3 GAK65778.1 - 0.026 13.7 0.5 0.039 13.2 0.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Bd3614_N PF14442.1 GAK65778.1 - 0.57 10.1 4.6 0.73 9.8 3.2 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal LSM PF01423.17 GAK65779.1 - 3.2e-15 55.4 0.9 4.2e-15 55.0 0.6 1.2 1 0 0 1 1 1 1 LSM domain NDK PF00334.14 GAK65780.1 - 5.4e-51 171.9 0.0 6.9e-51 171.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Sin_N PF04801.8 GAK65781.1 - 1e-24 87.2 0.0 1.2e-23 83.6 0.0 2.1 2 0 0 2 2 2 2 Sin-like protein conserved region Pex24p PF06398.6 GAK65782.1 - 2.4e-26 92.4 0.2 2.4e-26 92.4 0.2 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Gtr1_RagA PF04670.7 GAK65783.1 - 8.5e-28 97.0 1.9 4.4e-15 55.4 1.2 4.0 3 1 0 3 3 3 3 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAK65783.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase C1-set PF07654.10 GAK65783.1 - 0.053 13.5 0.2 0.18 11.8 0.0 2.0 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Arch_ATPase PF01637.13 GAK65783.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 GAK65783.1 - 0.13 12.7 0.0 15 6.1 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 GAK65783.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 GAK65783.1 - 0.16 11.2 0.1 1.8 7.7 0.1 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family RNase_P_pop3 PF08228.6 GAK65784.1 - 3.5e-05 23.6 0.0 8.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF2681 PF10883.3 GAK65784.1 - 5.3 7.3 6.7 16 5.8 4.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Oxysterol_BP PF01237.13 GAK65785.1 - 4.6e-64 216.1 0.0 1e-52 178.8 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein DNA_pol_viral_N PF00242.12 GAK65785.1 - 4.5 6.2 8.8 7.9 5.4 6.1 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ada3 PF10198.4 GAK65786.1 - 2.7e-37 127.4 1.7 2.7e-37 127.4 0.1 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 HEAT PF02985.17 GAK65787.1 - 4.1e-41 135.3 21.3 0.0014 18.4 0.0 13.6 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 GAK65787.1 - 3.9e-33 113.5 7.7 3.2e-09 36.9 0.0 6.8 2 1 5 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.2 GAK65787.1 - 1.8e-11 44.2 1.7 0.012 16.0 0.0 7.0 4 2 4 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAK65787.1 - 1.7e-08 34.6 14.0 0.63 10.6 0.0 8.5 7 2 1 8 8 8 3 HEAT-like repeat Adaptin_N PF01602.15 GAK65787.1 - 6.4e-07 28.0 7.2 0.084 11.1 0.1 4.8 3 1 1 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.3 GAK65787.1 - 0.0011 18.4 2.3 0.5 9.6 0.0 4.7 2 2 3 5 5 5 1 CLASP N terminal Arm PF00514.18 GAK65787.1 - 0.0017 18.0 0.7 6.9 6.6 0.0 5.8 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 GAK65787.1 - 0.051 12.7 0.4 0.66 9.0 0.3 2.8 1 1 0 1 1 1 0 V-ATPase subunit H HEAT_PBS PF03130.11 GAK65787.1 - 0.069 13.6 0.2 18 6.1 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF2435 PF10363.4 GAK65787.1 - 0.084 12.7 3.2 4.4 7.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) ACBP PF00887.14 GAK65788.1 - 2.3e-34 116.9 0.5 2.7e-34 116.6 0.3 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein SWIB PF02201.13 GAK65790.1 - 9e-17 60.5 0.0 1.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Memo PF01875.12 GAK65791.1 - 3.5e-75 252.4 0.0 5.8e-75 251.7 0.0 1.3 1 1 0 1 1 1 1 Memo-like protein Ribosomal_S3_C PF00189.15 GAK65792.1 - 2.4e-16 59.7 0.1 4.1e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 GAK65792.1 - 3.9e-13 48.7 0.0 6.4e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 GAK65792.1 - 0.049 13.9 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 HABP4_PAI-RBP1 PF04774.10 GAK65793.1 - 8e-10 39.1 7.4 8e-10 39.1 5.1 3.3 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Arrestin_N PF00339.24 GAK65794.1 - 4.9e-05 23.1 0.0 0.00034 20.4 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAK65794.1 - 0.00063 19.8 0.0 0.064 13.3 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 GAK65794.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein CAF-1_p150 PF11600.3 GAK65794.1 - 6.6 6.0 52.1 3.3e+02 0.5 36.1 2.7 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DZR PF12773.2 GAK65795.1 - 0.15 11.9 1.6 0.18 11.6 0.4 1.6 2 0 0 2 2 2 0 Double zinc ribbon SSF PF00474.12 GAK65796.1 - 2.4e-12 46.2 17.5 6.1e-12 44.8 12.1 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family RPAP2_Rtr1 PF04181.8 GAK65797.1 - 5.7e-16 58.3 0.0 1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family DAP3 PF10236.4 GAK65797.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NUDIX PF00293.23 GAK65798.1 - 3.3e-12 46.2 0.0 8.3e-12 44.9 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain TIMELESS PF04821.9 GAK65799.1 - 2.3e-32 112.3 10.8 1e-30 106.8 0.0 3.3 4 0 0 4 4 4 2 Timeless protein HLH PF00010.21 GAK65801.1 - 1.1e-18 66.6 0.0 3.2e-18 65.1 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF687 PF05095.7 GAK65801.1 - 2.2 6.5 4.2 3.4 5.9 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) DCP1 PF06058.8 GAK65802.1 - 9.7e-25 86.9 0.0 1.7e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family SR-25 PF10500.4 GAK65802.1 - 0.0032 16.9 12.8 0.0063 16.0 8.9 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BLVR PF06375.6 GAK65802.1 - 0.046 13.5 11.3 0.075 12.8 7.8 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Spore_coat_CotO PF14153.1 GAK65802.1 - 0.15 11.5 10.3 0.2 11.0 7.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RRN3 PF05327.6 GAK65802.1 - 0.22 9.5 1.8 0.27 9.2 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NARP1 PF12569.3 GAK65802.1 - 0.46 9.1 16.7 0.64 8.6 11.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 GAK65802.1 - 1.7 6.2 4.6 2.3 5.8 3.2 1.2 1 0 0 1 1 1 0 Ycf1 FancD2 PF14631.1 GAK65802.1 - 1.9 5.4 9.3 2.4 5.1 6.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF3987 PF13148.1 GAK65802.1 - 2.5 6.5 13.3 4.2 5.8 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rib_recp_KP_reg PF05104.7 GAK65802.1 - 3 8.3 29.5 1.3 9.4 18.8 1.6 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region DUF1510 PF07423.6 GAK65802.1 - 4.2 6.6 17.2 7 5.9 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 GAK65802.1 - 4.9 7.1 16.7 10 6.0 11.6 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paramyxo_ncap PF00973.14 GAK65802.1 - 5.2 5.6 8.2 7.6 5.0 5.7 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FLO_LFY PF01698.11 GAK65802.1 - 6.3 5.5 9.9 9.5 4.9 6.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Yippee-Mis18 PF03226.9 GAK65803.1 - 6.8e-20 70.9 0.0 1e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Redoxin PF08534.5 GAK65804.1 - 2.7e-34 117.7 0.1 3.8e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAK65804.1 - 2.1e-08 33.9 0.0 2.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Aa_trans PF01490.13 GAK65805.1 - 2.2e-80 270.1 33.4 2.6e-80 269.9 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Nucleoplasmin PF03066.10 GAK65805.1 - 0.045 13.2 3.6 0.17 11.4 2.4 1.8 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 GAK65805.1 - 0.65 10.2 9.7 1.8 8.8 6.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 GAK65805.1 - 2 6.3 3.9 3.7 5.4 2.7 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 GAK65805.1 - 9.2 5.4 6.3 15 4.6 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3395 PF11875.3 GAK65806.1 - 3.3e-34 117.6 0.0 6.1e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 GAK65806.1 - 6e-22 77.1 1.0 1.1e-21 76.3 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain Med5 PF08689.5 GAK65807.1 - 8.8e-31 106.4 0.0 2.1e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 Mediator complex subunit Med5 Amidohydro_1 PF01979.15 GAK65808.1 - 1.8e-36 126.4 0.0 1.5e-17 64.2 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.6 GAK65808.1 - 0.00085 18.6 0.1 0.15 11.2 0.1 3.0 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAK65808.1 - 0.0015 18.2 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase PAPS_reduct PF01507.14 GAK65809.1 - 2.6e-37 128.2 0.0 4e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF2849 PF11011.3 GAK65811.1 - 0.68 10.2 6.3 0.69 10.1 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) NTP_transferase PF00483.18 GAK65812.1 - 6.3e-45 153.4 0.0 9.4e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.13 GAK65812.1 - 1.3e-05 24.8 0.1 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Atg14 PF10186.4 GAK65813.1 - 6.7e-18 64.6 0.7 1.3e-17 63.7 0.5 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 GAK65813.1 - 3.8 5.2 4.8 5.5 4.7 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tim17 PF02466.14 GAK65814.1 - 0.03 14.3 1.4 0.03 14.3 1.0 2.9 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 GAK65814.1 - 5.7 6.6 9.4 15 5.2 1.4 2.9 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Ribosomal_L36 PF00444.13 GAK65815.1 - 1.5e-22 79.2 7.7 2.6e-22 78.5 5.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 VBS PF08913.5 GAK65815.1 - 0.075 13.2 1.7 0.087 13.0 1.2 1.1 1 0 0 1 1 1 0 Vinculin Binding Site RE_SacI PF09566.5 GAK65815.1 - 0.12 11.2 0.2 0.14 11.0 0.2 1.1 1 0 0 1 1 1 0 SacI restriction endonuclease Urb2 PF10441.4 GAK65816.1 - 9.2e-38 130.0 2.4 1.3e-36 126.2 0.0 3.1 3 0 0 3 3 3 2 Urb2/Npa2 family Ctf8 PF09696.5 GAK65817.1 - 3.2e-19 68.8 0.4 3.1e-11 43.1 0.0 2.4 2 1 0 2 2 2 2 Ctf8 PapD-like PF14874.1 GAK65819.1 - 4.9e-07 29.6 0.1 0.25 11.3 0.0 4.9 5 0 0 5 5 5 3 Flagellar-associated PapD-like PUF PF00806.14 GAK65821.1 - 4.1e-09 35.4 0.0 0.0015 17.8 0.0 5.8 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat Frag1 PF10277.4 GAK65822.1 - 1.2e-37 129.5 5.0 1.2e-37 129.5 3.5 2.4 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family TRAM_LAG1_CLN8 PF03798.11 GAK65825.1 - 1.5e-28 99.7 27.8 1.5e-28 99.7 19.3 2.1 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.6 GAK65825.1 - 1.3e-14 53.3 0.0 1.3e-14 53.3 0.0 2.6 3 1 0 3 3 3 1 TRAM1-like protein Succ_CoA_lig PF13607.1 GAK65825.1 - 0.028 14.0 1.8 0.06 12.9 1.3 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Herpes_capsid PF06112.6 GAK65825.1 - 4.8 7.2 7.9 19 5.2 4.4 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF1279 PF06916.8 GAK65827.1 - 9.5e-23 80.3 0.0 1.5e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Peroxin-3 PF04882.7 GAK65827.1 - 0.11 11.2 0.8 0.43 9.2 0.0 1.9 2 0 0 2 2 2 0 Peroxin-3 Ribosomal_L13e PF01294.13 GAK65829.1 - 1.8e-65 219.7 7.8 2.4e-65 219.3 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Herpes_US12 PF05363.7 GAK65829.1 - 0.78 10.2 3.3 5.6 7.5 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus US12 family NIR_SIR PF01077.17 GAK65830.1 - 9.6e-44 148.4 0.0 2.2e-39 134.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 GAK65830.1 - 1.5e-29 101.3 0.0 1.1e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 GAK65830.1 - 4.4e-26 91.5 0.0 8.8e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 GAK65830.1 - 3.4e-09 36.5 0.2 7.9e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg His_Phos_1 PF00300.17 GAK65832.1 - 7.8e-20 71.5 0.0 1.5e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Dus PF01207.12 GAK65833.1 - 2.3e-40 138.3 0.3 3.6e-40 137.7 0.2 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyridox_oxase_2 PF12766.2 GAK65833.1 - 8.9e-24 83.7 0.0 2e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Vps39_1 PF10366.4 GAK65834.1 - 5e-30 103.6 0.0 1.6e-29 102.0 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 GAK65834.1 - 5.7e-29 100.4 0.1 1.3e-28 99.3 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 GAK65834.1 - 2.8e-15 56.4 0.0 4.8e-05 22.9 0.0 3.3 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.15 GAK65834.1 - 8e-08 31.9 0.0 0.00067 19.2 0.0 3.6 3 1 0 3 3 3 2 Region in Clathrin and VPS Apc3 PF12895.2 GAK65834.1 - 0.015 15.3 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RHS PF03527.9 GAK65834.1 - 0.17 11.6 0.3 0.4 10.4 0.2 1.6 1 0 0 1 1 1 0 RHS protein TPR_12 PF13424.1 GAK65834.1 - 0.58 10.1 4.9 2.5 8.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Aminotran_3 PF00202.16 GAK65836.1 - 5e-40 137.3 0.0 8.8e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.1 GAK65836.1 - 4e-25 88.5 0.0 8.4e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain HemX PF04375.9 GAK65837.1 - 0.00049 18.8 0.6 0.00082 18.0 0.4 1.3 1 0 0 1 1 1 1 HemX DGCR6 PF07324.6 GAK65837.1 - 0.011 15.1 1.1 0.011 15.1 0.7 1.6 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.4 GAK65837.1 - 0.072 12.9 2.2 0.38 10.6 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) DLIC PF05783.6 GAK65837.1 - 0.14 10.8 0.2 0.22 10.1 0.2 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Nsp1_C PF05064.8 GAK65837.1 - 0.48 10.0 6.3 3.2 7.4 0.2 2.8 2 1 1 3 3 3 0 Nsp1-like C-terminal region THUMP PF02926.12 GAK65838.1 - 3.6e-08 33.3 0.0 8.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 THUMP domain ASD2 PF08687.6 GAK65838.1 - 0.15 11.3 1.7 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Adaptin_N PF01602.15 GAK65839.1 - 2.7e-05 22.7 2.4 0.008 14.5 0.0 4.1 4 1 1 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 GAK65839.1 - 0.0004 20.7 0.0 0.25 11.7 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 GAK65839.1 - 0.00063 19.4 0.4 0.017 14.9 0.1 3.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAK65839.1 - 0.00065 19.5 0.3 0.026 14.5 0.1 9.7 12 0 0 12 12 12 2 HEAT repeat Cnd1 PF12717.2 GAK65839.1 - 0.0083 15.9 0.0 3.7 7.3 0.0 4.1 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAK65839.1 - 0.009 16.2 38.7 0.032 14.5 0.0 10.1 9 3 1 10 10 10 3 HEAT repeats HEAT_EZ PF13513.1 GAK65839.1 - 0.0095 16.4 32.8 0.13 12.8 0.1 9.7 9 1 2 11 11 11 2 HEAT-like repeat UCH PF00443.24 GAK65840.1 - 2.1e-40 138.5 0.0 4.8e-40 137.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 GAK65840.1 - 6.9e-20 70.2 4.3 8e-19 66.8 1.2 2.9 2 0 0 2 2 2 1 A repeated domain in UCH-protein UCH_1 PF13423.1 GAK65840.1 - 1.7e-09 37.5 0.0 0.003 17.0 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase CENP-F_leu_zip PF10473.4 GAK65840.1 - 0.42 10.4 6.2 0.73 9.6 0.1 2.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 GAK65840.1 - 3.1 6.6 5.2 9.7 5.0 0.8 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Vps8 PF12816.2 GAK65842.1 - 2.4e-51 173.7 0.0 1.9e-50 170.8 0.0 2.2 1 1 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.27 GAK65842.1 - 0.12 12.3 0.3 0.4 10.6 0.2 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 GAK65842.1 - 0.82 9.7 0.1 2 8.5 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) dUTPase PF00692.14 GAK65843.1 - 8.8e-43 144.8 0.0 1.2e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase Dynamin_N PF00350.18 GAK65844.1 - 1.5e-42 145.2 0.0 6.1e-42 143.2 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 GAK65844.1 - 7.2e-07 28.2 0.0 6.5e-05 21.8 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 GAK65844.1 - 0.00042 20.2 0.0 0.0043 16.9 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAK65844.1 - 0.0061 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 GAK65844.1 - 0.0083 16.1 0.2 0.48 10.3 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 GAK65844.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cation_efflux PF01545.16 GAK65845.1 - 2.8e-78 262.8 9.0 1e-77 261.0 6.2 1.7 1 1 0 1 1 1 1 Cation efflux family VirB3 PF05101.8 GAK65845.1 - 9.7 6.2 8.3 0.65 10.0 0.8 2.6 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein PC_rep PF01851.17 GAK65846.1 - 3.1e-18 64.9 17.3 0.0033 17.5 0.0 8.6 8 0 0 8 8 8 5 Proteasome/cyclosome repeat Bac_surface_Ag PF01103.18 GAK65849.1 - 1.5e-35 123.1 0.1 6.2e-35 121.1 0.1 1.8 1 1 0 1 1 1 1 Surface antigen RNA_pol_Rbc25 PF08292.7 GAK65850.1 - 5e-40 136.4 0.0 6.6e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 GAK65850.1 - 3.5e-19 68.6 0.0 5.6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RhoGAP PF00620.22 GAK65851.1 - 3.8e-37 127.2 0.0 5.8e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 GAK65851.1 - 0.00068 18.5 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF1741 PF08427.5 GAK65854.1 - 3.6e-46 157.5 0.0 5.5e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) SEP PF08059.8 GAK65855.1 - 3.1e-26 91.4 0.0 5.6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 GAK65855.1 - 7.3e-18 64.4 0.0 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 GAK65855.1 - 1.3e-15 56.5 0.3 2.4e-15 55.7 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain PBP1_TM PF14812.1 GAK65855.1 - 2.2 8.6 6.4 0.87 9.9 2.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim17 PF02466.14 GAK65856.1 - 3.9e-14 52.7 12.4 5.7e-14 52.2 8.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 GAK65856.1 - 1.4 8.2 8.1 1.4 8.2 4.2 1.7 1 1 1 2 2 2 0 5TMR of 5TMR-LYT tRNA_bind PF01588.15 GAK65857.1 - 2.8e-27 94.3 0.0 6.6e-27 93.1 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 GAK65857.1 - 0.00025 20.9 2.2 0.00035 20.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAK65857.1 - 0.00041 20.7 0.3 0.0014 19.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAK65857.1 - 0.00069 19.4 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain U79_P34 PF03064.11 GAK65857.1 - 0.044 13.3 7.0 0.068 12.6 4.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNase_H2-Ydr279 PF09468.5 GAK65857.1 - 0.11 11.6 7.1 0.21 10.7 4.9 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 GAK65857.1 - 3.4 7.4 10.5 6.4 6.5 7.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 adh_short PF00106.20 GAK65858.1 - 8.5e-05 22.5 0.2 6.1 6.7 0.0 3.5 3 0 0 3 3 3 3 short chain dehydrogenase DUF3425 PF11905.3 GAK65861.1 - 3.9e-29 101.2 0.0 7.1e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAK65861.1 - 1.5e-05 24.8 8.4 3e-05 23.8 5.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAK65861.1 - 0.1 12.4 11.5 0.2 11.5 7.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Macoilin PF09726.4 GAK65861.1 - 9.7 4.3 12.4 19 3.4 5.7 2.1 2 0 0 2 2 2 0 Transmembrane protein UDPGP PF01704.13 GAK65862.1 - 5.4e-47 160.2 0.0 9.7e-47 159.3 0.0 1.3 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_L4 PF00573.17 GAK65863.1 - 8.2e-45 152.5 0.7 1.6e-44 151.6 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 GAK65863.1 - 2.5e-28 97.7 5.0 3.1e-28 97.4 0.8 2.6 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain CAP_N PF01213.14 GAK65864.1 - 0.062 12.5 0.3 0.062 12.5 0.2 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Aconitase PF00330.15 GAK65865.1 - 6.3e-176 585.4 0.1 1.4e-175 584.3 0.1 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAK65865.1 - 5.4e-43 146.2 0.0 1.1e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 GAK65865.1 - 0.042 12.4 0.0 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MFS_1 PF07690.11 GAK65866.1 - 4e-28 98.1 34.5 3.3e-25 88.5 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK65866.1 - 1.4e-20 73.3 12.3 5.7e-20 71.3 8.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Chalcone PF02431.10 GAK65867.1 - 2.8e-42 144.3 0.0 3.6e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Anti-adapt_IraP PF10796.4 GAK65867.1 - 0.088 13.1 0.5 0.63 10.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Acetyltransf_1 PF00583.19 GAK65868.1 - 1.3e-15 57.1 0.0 1.9e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK65868.1 - 5.3e-12 45.7 0.1 7.5e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAK65868.1 - 0.00071 19.4 0.0 0.00095 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK65868.1 - 0.002 17.8 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 GAK65868.1 - 0.0047 16.8 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAK65868.1 - 0.015 15.3 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAK65868.1 - 0.03 14.1 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Hemerythrin PF01814.18 GAK65869.1 - 0.49 10.5 3.0 0.71 10.0 0.5 2.1 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain ADH_N PF08240.7 GAK65871.1 - 7e-27 93.3 4.7 1.2e-26 92.5 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK65871.1 - 2.4e-14 53.0 0.0 8.1e-14 51.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK65871.1 - 0.11 13.3 0.0 0.19 12.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAK65871.1 - 0.12 11.4 0.2 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNARE PF05739.14 GAK65872.1 - 1.5e-06 27.8 0.6 1.5e-06 27.8 0.4 3.3 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 GAK65872.1 - 0.01 15.8 2.6 0.87 9.7 0.3 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF1490 PF07371.7 GAK65872.1 - 2.9 7.9 5.0 0.63 10.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Prefoldin_2 PF01920.15 GAK65873.1 - 1.7e-17 63.0 9.4 2.8e-17 62.4 6.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF4349 PF14257.1 GAK65873.1 - 0.05 12.8 11.6 0.62 9.2 1.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) EMP24_GP25L PF01105.19 GAK65873.1 - 0.052 13.2 5.3 0.79 9.4 0.4 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF904 PF06005.7 GAK65873.1 - 0.056 13.7 2.6 0.056 13.7 1.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) MscS_porin PF12795.2 GAK65873.1 - 0.076 12.3 25.2 0.023 14.0 6.7 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.6 GAK65873.1 - 0.54 10.1 2.7 4.4 7.2 0.2 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Suppressor_APC PF11414.3 GAK65873.1 - 0.7 9.7 11.1 0.05 13.3 2.3 2.4 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein RasGAP_C PF03836.10 GAK65873.1 - 0.88 9.2 12.0 0.04 13.6 2.7 2.3 2 1 0 2 2 2 0 RasGAP C-terminus Atg14 PF10186.4 GAK65873.1 - 2 7.3 15.6 0.96 8.3 2.5 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 GAK65873.1 - 2 8.8 7.9 6.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 GAK65873.1 - 2.3 8.5 8.9 5.1 7.4 1.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 GAK65873.1 - 2.3 8.7 13.7 6.3 7.3 1.1 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.2 GAK65873.1 - 3.2 7.6 14.5 0.26 11.1 4.0 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF3847 PF12958.2 GAK65873.1 - 3.3 7.5 9.4 1.4 8.7 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Baculo_PEP_C PF04513.7 GAK65873.1 - 5.7 6.7 11.2 69 3.2 6.7 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NTR2 PF15458.1 GAK65873.1 - 5.8 6.0 14.3 4.6 6.4 1.7 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 XhlA PF10779.4 GAK65873.1 - 7.8 6.5 8.1 0.41 10.5 0.8 2.3 2 1 1 3 3 3 0 Haemolysin XhlA DivIC PF04977.10 GAK65873.1 - 7.9 6.0 14.3 7.1 6.2 3.1 2.4 2 0 0 2 2 2 0 Septum formation initiator RhoGEF PF00621.15 GAK65874.1 - 3e-12 46.8 0.0 1.1e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CSTF2_hinge PF14327.1 GAK65875.1 - 6e-31 106.3 2.0 6e-31 106.3 1.4 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 GAK65875.1 - 2.2e-23 81.6 0.1 3.5e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK65875.1 - 2.8e-17 62.4 0.0 5.3e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 GAK65875.1 - 2e-11 42.9 6.4 2e-11 42.9 4.4 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 GAK65875.1 - 1.5e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2315 PF10231.4 GAK65876.1 - 4.5e-15 55.6 0.8 2.7e-10 40.1 0.5 2.4 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2315) Mis14 PF08641.7 GAK65878.1 - 1.4e-05 25.1 5.5 3.4e-05 23.9 3.8 1.7 1 1 0 1 1 1 1 Kinetochore protein Mis14 like HAUS5 PF14817.1 GAK65878.1 - 0.015 13.8 6.4 0.019 13.5 4.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Striatin PF08232.7 GAK65878.1 - 0.033 14.5 3.1 0.07 13.4 2.1 1.6 1 0 0 1 1 1 0 Striatin family Tir_receptor_C PF07489.6 GAK65878.1 - 0.083 12.6 0.6 0.12 12.1 0.4 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Atg14 PF10186.4 GAK65878.1 - 0.15 10.9 4.2 0.18 10.6 2.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pinin_SDK_memA PF04696.8 GAK65878.1 - 0.19 11.3 5.0 0.37 10.3 3.5 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region COG2 PF06148.6 GAK65878.1 - 1.7 8.4 5.7 0.83 9.5 1.2 2.3 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3087 PF11286.3 GAK65879.1 - 0.068 12.3 0.1 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) zf-CCHC PF00098.18 GAK65880.1 - 0.041 13.8 0.9 0.078 12.9 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4 PF00097.20 GAK65880.1 - 1.2 8.8 7.4 1.9 8.2 5.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1674 PF07896.7 GAK65881.1 - 6.8e-13 48.6 6.4 1.3e-12 47.6 4.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) APG6 PF04111.7 GAK65882.1 - 2.6 7.0 9.2 3.9 6.4 6.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CAF-1_p150 PF11600.3 GAK65882.1 - 3.4 7.0 21.9 0.029 13.7 9.0 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal IncA PF04156.9 GAK65882.1 - 6.4 6.3 13.9 11 5.5 9.6 1.3 1 0 0 1 1 1 0 IncA protein RQC PF09382.5 GAK65883.1 - 5.3e-24 83.9 0.6 1.2e-23 82.8 0.4 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 GAK65883.1 - 2.1e-21 76.1 0.0 5.5e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK65883.1 - 8.6e-19 67.1 0.0 7.4e-18 64.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 GAK65883.1 - 6.2e-06 25.8 0.0 1.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Sigma70_ner PF04546.8 GAK65883.1 - 0.00059 19.5 1.9 0.00059 19.5 1.3 2.2 3 0 0 3 3 3 1 Sigma-70, non-essential region Helicase_Sgs1 PF11408.3 GAK65883.1 - 0.031 14.0 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase Prenyltrans PF00432.16 GAK65884.1 - 0.027 14.0 0.4 3.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat B56 PF01603.15 GAK65885.1 - 4.5e-171 568.9 9.4 5.5e-171 568.6 6.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) LamB_YcsF PF03746.11 GAK65886.1 - 1.9e-69 233.4 0.0 3.8e-69 232.4 0.0 1.4 1 1 0 1 1 1 1 LamB/YcsF family AHS2 PF02626.10 GAK65887.1 - 6.7e-61 205.9 0.0 1e-60 205.3 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 GAK65887.1 - 1.1e-54 184.8 0.0 2e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 GAK65887.1 - 5.6e-32 110.8 0.0 1.5e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 GAK65887.1 - 3.2e-30 104.4 0.0 1e-29 102.8 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAK65887.1 - 9.2e-28 96.3 0.0 5.2e-27 93.9 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 GAK65887.1 - 2.8e-18 66.2 0.0 8e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAK65887.1 - 3.6e-13 48.9 0.4 8e-13 47.8 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 GAK65887.1 - 2e-09 37.1 0.0 4.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAK65887.1 - 8e-06 25.3 0.0 2.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAK65887.1 - 9.1e-06 25.2 0.0 2.5e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAK65887.1 - 0.00026 20.8 0.0 0.00052 19.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 GAK65887.1 - 0.0082 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAK65887.1 - 0.059 13.0 0.2 1.1 9.0 0.1 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.1 GAK65887.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Cornichon PF03311.9 GAK65888.1 - 3.8e-47 159.5 5.6 4.6e-47 159.3 3.9 1.1 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 GAK65888.1 - 0.017 14.6 1.2 0.022 14.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) PDCD2_C PF04194.8 GAK65889.1 - 2.5e-24 85.7 11.6 8.4e-24 84.0 0.0 4.7 4 1 0 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain Nop14 PF04147.7 GAK65889.1 - 0.047 11.6 7.8 0.068 11.0 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family MFS_2 PF13347.1 GAK65890.1 - 7.2e-06 24.6 4.4 7.2e-06 24.6 3.0 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAK65890.1 - 0.072 12.8 0.0 0.072 12.8 0.0 4.2 4 1 0 4 4 4 0 MFS_1 like family NIPSNAP PF07978.8 GAK65890.1 - 0.097 12.6 0.2 0.097 12.6 0.1 2.5 3 0 0 3 3 3 0 NIPSNAP GTP_EFTU PF00009.22 GAK65891.1 - 1.6e-43 148.3 0.0 2.2e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAK65891.1 - 7e-28 96.6 0.0 1.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAK65891.1 - 2.1e-19 69.1 0.0 4.6e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 GAK65891.1 - 7.3e-09 36.1 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAK65891.1 - 6.9e-07 29.2 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 GAK65891.1 - 6.3e-05 22.7 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 GAK65891.1 - 0.00014 21.9 0.1 0.0003 20.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 GAK65891.1 - 0.0022 17.8 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Ras PF00071.17 GAK65891.1 - 0.0032 16.8 0.0 0.0097 15.3 0.0 1.8 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 GAK65891.1 - 0.019 14.2 0.0 0.044 12.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CbiA PF01656.18 GAK65891.1 - 0.065 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glutaredoxin PF00462.19 GAK65892.1 - 1.7e-16 59.9 0.1 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin bZIP_1 PF00170.16 GAK65893.1 - 2.7e-06 27.2 10.1 2.7e-06 27.2 7.0 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAK65893.1 - 0.0027 17.4 5.9 0.006 16.3 4.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper MatP PF06303.7 GAK65893.1 - 0.2 11.5 1.3 0.43 10.4 0.9 1.4 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome bZIP_Maf PF03131.12 GAK65893.1 - 1.7 8.9 14.2 0.26 11.6 5.2 3.0 3 1 0 3 3 3 0 bZIP Maf transcription factor Fasciclin PF02469.17 GAK65894.1 - 3.6e-23 81.9 0.1 3e-14 53.1 0.0 3.4 3 0 0 3 3 3 3 Fasciclin domain DAG_kinase_N PF14513.1 GAK65894.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus COesterase PF00135.23 GAK65895.1 - 1.2e-76 258.5 0.0 3e-76 257.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAK65895.1 - 1.9e-07 30.8 4.1 0.0022 17.5 0.3 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold XPG_I PF00867.13 GAK65896.1 - 1.4e-20 73.1 0.0 6.1e-20 71.0 0.0 2.0 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAK65896.1 - 5.6e-05 23.3 0.0 0.00055 20.1 0.0 2.5 2 1 0 2 2 2 1 XPG N-terminal domain Abhydrolase_6 PF12697.2 GAK65897.1 - 3e-12 46.8 2.3 3e-12 46.8 1.6 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK65897.1 - 2.5e-07 30.5 0.1 5.4e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 GAK65897.1 - 0.00048 19.1 0.0 0.00077 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 GAK65897.1 - 0.00053 19.2 0.0 0.037 13.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAK65897.1 - 0.00084 18.9 0.0 0.003 17.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.6 GAK65897.1 - 0.025 13.6 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2423 PF10338.4 GAK65898.1 - 1.3e-15 57.0 4.1 2.2e-15 56.3 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Ank_2 PF12796.2 GAK65899.1 - 1.4e-43 147.1 5.3 1.4e-17 63.8 0.1 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAK65899.1 - 2.1e-36 121.9 11.5 1.4e-07 30.9 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 GAK65899.1 - 2.6e-33 113.7 2.6 8.3e-11 42.1 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 GAK65899.1 - 6.7e-32 111.3 7.1 1.6e-19 70.7 0.2 2.2 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 GAK65899.1 - 2e-26 91.3 9.9 5.3e-05 23.3 0.0 7.3 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK65899.1 - 1.8e-24 83.3 6.9 0.00048 20.0 0.0 8.0 8 0 0 8 8 8 4 Ankyrin repeat GDPD PF03009.12 GAK65899.1 - 1.9e-13 50.5 0.0 7.2e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CRM1_C PF08767.6 GAK65900.1 - 5.8e-128 426.2 1.8 1.4e-127 425.0 0.0 2.5 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 GAK65900.1 - 3.6e-41 140.5 0.8 3.6e-41 140.5 0.5 3.7 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 GAK65900.1 - 9.5e-15 54.2 1.5 4.5e-14 52.1 0.7 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain V-SNARE_C PF12352.3 GAK65901.1 - 3.2e-17 62.3 0.7 3.2e-17 62.3 0.5 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus CENP-Q PF13094.1 GAK65901.1 - 0.044 13.8 0.1 0.069 13.1 0.1 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 GAK65901.1 - 0.083 12.7 1.1 15 5.3 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nucleoporin_C PF03177.9 GAK65902.1 - 2.1e-86 290.7 1.4 3.1e-86 290.2 1.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal WD40 PF00400.27 GAK65902.1 - 8.5e-27 92.0 11.3 7.7e-08 31.9 0.5 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAK65902.1 - 8.3e-15 54.4 0.0 2.9e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Nup133 N terminal like Fungal_trans PF04082.13 GAK65902.1 - 9.9e-12 44.2 0.0 2.9e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain CLTH PF10607.4 GAK65902.1 - 0.00029 20.5 0.2 0.0007 19.3 0.1 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-C2H2 PF00096.21 GAK65902.1 - 0.033 14.5 6.7 0.011 16.0 0.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type LisH PF08513.6 GAK65902.1 - 0.28 11.0 0.2 0.84 9.4 0.1 1.9 1 0 0 1 1 1 0 LisH DUF1887 PF09002.6 GAK65902.1 - 0.79 8.0 0.1 1.3 7.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) zf-C2H2_4 PF13894.1 GAK65902.1 - 1.4 9.4 7.7 0.14 12.5 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAK65902.1 - 2.1 8.8 3.7 1.1 9.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Glyco_tranf_2_2 PF10111.4 GAK65902.1 - 7.9 5.4 0.1 15 4.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 HRDC PF00570.18 GAK65903.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 HRDC domain DUF2786 PF10979.3 GAK65909.1 - 1.6e-11 43.7 1.5 1.6e-11 43.7 1.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) Guanylate_kin PF00625.16 GAK65910.1 - 4.3e-58 195.7 0.0 5.3e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 GAK65910.1 - 2.7e-08 34.0 0.0 8.9e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAK65910.1 - 1.7e-05 24.9 0.0 0.00011 22.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAK65910.1 - 4e-05 23.9 0.0 0.00087 19.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain DUF258 PF03193.11 GAK65910.1 - 6.5e-05 22.1 0.0 9.7e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAK65910.1 - 0.0001 23.1 0.1 0.00027 21.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAK65910.1 - 0.00018 21.3 0.0 0.0033 17.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAK65910.1 - 0.00048 19.8 0.0 0.003 17.2 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 GAK65910.1 - 0.00075 19.0 0.1 0.0038 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 GAK65910.1 - 0.00081 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 GAK65910.1 - 0.00083 19.2 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAK65910.1 - 0.0023 18.2 0.0 0.0052 17.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 GAK65910.1 - 0.0024 17.5 0.0 0.0074 15.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 GAK65910.1 - 0.0028 17.8 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 GAK65910.1 - 0.003 17.2 0.0 0.0058 16.3 0.0 1.6 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.1 GAK65910.1 - 0.0035 17.3 0.1 0.043 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAK65910.1 - 0.0042 17.0 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 GAK65910.1 - 0.0071 16.0 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.12 GAK65910.1 - 0.0076 15.6 0.0 0.038 13.3 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase Miro PF08477.8 GAK65910.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA PF00004.24 GAK65910.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAK65910.1 - 0.033 12.8 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein T2SE PF00437.15 GAK65910.1 - 0.04 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 GAK65910.1 - 0.049 12.6 0.0 0.076 11.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 GAK65910.1 - 0.069 11.9 0.1 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF4072 PF13284.1 GAK65910.1 - 0.099 12.8 0.8 0.31 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) NB-ARC PF00931.17 GAK65910.1 - 0.12 11.2 0.0 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain PCMT PF01135.14 GAK65911.1 - 2.7e-67 226.3 0.0 3.1e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 GAK65911.1 - 5e-08 33.5 0.0 7.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK65911.1 - 1.7e-07 30.9 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK65911.1 - 3.6e-06 27.2 0.0 6.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK65911.1 - 3.1e-05 23.9 0.1 5.4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK65911.1 - 0.00016 22.0 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK65911.1 - 0.00017 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAK65911.1 - 0.0019 17.3 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 GAK65911.1 - 0.0027 17.4 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK65911.1 - 0.053 12.8 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.6 GAK65911.1 - 0.07 11.8 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) UQ_con PF00179.21 GAK65912.1 - 5.1e-38 129.6 0.1 7.2e-38 129.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 GAK65912.1 - 0.039 13.6 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 GAK65912.1 - 0.11 12.4 2.0 0.16 11.8 1.4 1.4 1 1 0 1 1 1 0 RWD domain Exo_endo_phos PF03372.18 GAK65913.1 - 1e-23 84.5 0.3 1.4e-23 84.1 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 GAK65914.1 - 3.3e-17 61.6 6.8 4.8e-05 23.0 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Vps54 PF07928.7 GAK65915.1 - 6e-54 181.8 0.9 1.5e-53 180.5 0.6 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 GAK65915.1 - 8.7e-08 31.4 1.2 3.1e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) PsaM PF07465.8 GAK65915.1 - 0.032 13.8 0.1 0.067 12.8 0.1 1.5 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) LEA_2 PF03168.8 GAK65916.1 - 0.00046 20.5 0.1 0.00088 19.6 0.1 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 GAK65916.1 - 0.0014 17.8 0.8 0.0028 16.9 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Shisa PF13908.1 GAK65916.1 - 8 6.6 6.1 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Peptidase_S8 PF00082.17 GAK65917.1 - 1.1e-56 192.1 1.9 1.5e-56 191.6 1.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 GAK65917.1 - 4.6e-28 96.8 0.1 1e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain P12 PF12669.2 GAK65917.1 - 0.37 11.0 1.4 0.8 9.9 0.4 1.9 2 0 0 2 2 2 0 Virus attachment protein p12 family MIP PF00230.15 GAK65918.1 - 8.9e-45 152.8 13.4 1.2e-44 152.4 9.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein hNIFK_binding PF12196.3 GAK65918.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK CPSF100_C PF13299.1 GAK65919.1 - 1.4e-23 83.8 0.0 3.5e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 GAK65919.1 - 2.9e-22 78.9 0.0 6.6e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 GAK65919.1 - 1.5e-05 24.6 0.0 3.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAK65919.1 - 0.015 14.9 0.3 0.12 11.9 0.2 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF3553 PF12073.3 GAK65919.1 - 0.018 14.3 0.0 9 5.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3553) DUF3740 PF12548.3 GAK65919.1 - 0.23 11.7 2.0 2.4 8.4 0.3 2.8 3 0 0 3 3 3 0 Sulfatase protein PTCB-BRCT PF12738.2 GAK65920.1 - 3.5e-05 23.5 0.2 9.5e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain fn3 PF00041.16 GAK65920.1 - 0.00064 19.8 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain BRCT PF00533.21 GAK65920.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 GAK65920.1 - 0.02 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF605 PF04652.11 GAK65920.1 - 2.7 7.3 30.4 3.9 6.7 21.1 1.2 1 0 0 1 1 1 0 Vta1 like F-box PF00646.28 GAK65921.1 - 1.3e-07 31.0 0.3 2.3e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAK65921.1 - 3.4e-07 29.8 0.7 6.4e-07 28.9 0.5 1.4 1 0 0 1 1 1 1 F-box-like Lactamase_B_3 PF13483.1 GAK65922.1 - 7.6e-07 28.9 0.0 4.8e-06 26.3 0.0 2.0 1 1 1 2 2 2 1 Beta-lactamase superfamily domain P34-Arc PF04045.9 GAK65923.1 - 1.2e-104 348.8 0.0 1.7e-104 348.3 0.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF2361 PF10153.4 GAK65924.1 - 0.098 12.8 0.1 0.098 12.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) FYDLN_acid PF09538.5 GAK65924.1 - 0.3 11.6 7.5 0.13 12.8 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TEA PF01285.13 GAK65926.1 - 6.1e-36 124.5 0.0 4.7e-35 121.5 0.0 2.3 1 1 0 1 1 1 1 TEA/ATTS domain family Pkinase PF00069.20 GAK65927.1 - 2.2e-50 171.2 0.0 3.2e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK65927.1 - 1.7e-45 155.1 0.0 2.3e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sec66 PF09802.4 GAK65928.1 - 2.9e-48 163.7 0.0 4.6e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Phage_Mu_F PF04233.9 GAK65928.1 - 0.036 14.5 1.8 0.15 12.5 0.7 2.2 2 0 0 2 2 2 0 Phage Mu protein F like protein DUF3708 PF12501.3 GAK65928.1 - 0.17 11.7 6.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter LcrG PF07216.7 GAK65928.1 - 0.86 9.6 6.6 0.77 9.8 0.1 2.5 2 0 0 2 2 2 0 LcrG protein PAT1 PF09770.4 GAK65928.1 - 2.4 6.2 22.4 3.4 5.8 15.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RasGEF PF00617.14 GAK65929.1 - 2.9e-63 213.0 0.8 1.4e-62 210.7 0.1 2.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 GAK65929.1 - 9.5e-29 99.5 0.2 2.1e-28 98.4 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 GAK65929.1 - 5e-14 51.4 0.0 1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAK65929.1 - 3.8e-12 45.5 0.1 7.3e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAK65929.1 - 7.2e-11 41.4 0.0 1.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAE2 PF08573.5 GAK65930.1 - 3e-10 40.6 5.9 1.1e-08 35.6 0.3 3.2 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HrpA_pilin PF09589.5 GAK65930.1 - 0.067 13.6 0.8 0.14 12.6 0.4 1.8 2 0 0 2 2 2 0 HrpA pilus formation protein UEV PF05743.8 GAK65931.1 - 6e-38 129.2 0.0 9e-38 128.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 GAK65931.1 - 2.1e-27 94.4 2.1 2.5e-27 94.2 0.3 1.9 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.21 GAK65931.1 - 0.0084 15.5 0.1 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-Mss51 PF13824.1 GAK65932.1 - 4.1e-22 77.7 1.0 8.6e-22 76.7 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Epimerase PF01370.16 GAK65933.1 - 4.4e-43 147.3 0.0 6.9e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAK65933.1 - 1.3e-09 37.3 0.1 7.9e-06 24.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 GAK65933.1 - 1.9e-09 36.6 0.0 2.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAK65933.1 - 2e-06 26.8 0.0 5.7e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAK65933.1 - 5.9e-05 22.1 0.1 0.0011 17.9 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAK65933.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 GAK65933.1 - 0.023 14.6 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Lactamase_B_2 PF12706.2 GAK65934.1 - 1.3e-25 90.0 0.1 5.8e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAK65934.1 - 2.7e-08 33.6 0.0 1.4e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 GAK65935.1 - 1.3e-21 76.6 0.0 2.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK65935.1 - 1.9e-06 27.6 8.7 3.9e-06 26.6 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4188 PF13826.1 GAK65936.1 - 8.6e-24 83.8 0.0 1.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) TPR_MLP1_2 PF07926.7 GAK65937.1 - 0.0015 18.2 2.4 0.14 11.9 0.1 2.9 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein Filament PF00038.16 GAK65937.1 - 0.0065 15.9 0.8 0.013 15.0 0.6 1.4 1 0 0 1 1 1 1 Intermediate filament protein FlgN PF05130.7 GAK65937.1 - 0.15 12.3 0.1 0.15 12.3 0.1 3.1 3 0 0 3 3 3 0 FlgN protein HAP1_N PF04849.8 GAK65937.1 - 0.22 10.4 5.5 0.66 8.8 0.1 2.7 3 0 0 3 3 3 0 HAP1 N-terminal conserved region DUF972 PF06156.8 GAK65937.1 - 3.3 8.0 3.5 85 3.5 1.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 GAK65937.1 - 3.9 7.0 11.7 2 7.9 0.3 3.0 2 1 1 3 3 3 0 Septum formation initiator CHORD PF04968.7 GAK65939.1 - 9.3e-48 160.3 11.0 1.1e-24 86.4 2.4 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 GAK65939.1 - 1.2e-06 28.9 0.0 2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 CS domain BTK PF00779.14 GAK65939.1 - 0.011 15.3 8.3 0.15 11.6 1.3 3.2 3 1 0 3 3 3 0 BTK motif DUF2733 PF10813.3 GAK65939.1 - 0.38 10.3 3.9 9 5.9 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Ribosomal_60s PF00428.14 GAK65939.1 - 4.8 7.6 12.7 28 5.1 8.8 2.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein AAA PF00004.24 GAK65940.1 - 8.1e-14 51.9 0.0 2.4e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAK65940.1 - 3.8e-05 22.5 0.2 0.26 9.9 0.0 2.8 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 GAK65940.1 - 0.0001 21.9 0.1 0.0005 19.7 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 GAK65940.1 - 0.00022 20.3 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAK65940.1 - 0.00028 20.7 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK65940.1 - 0.00029 21.6 0.3 0.0011 19.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 GAK65940.1 - 0.0016 17.8 0.0 0.48 9.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAK65940.1 - 0.0017 18.4 0.0 0.91 9.4 0.1 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAK65940.1 - 0.019 15.0 0.0 0.081 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAK65940.1 - 0.031 14.1 0.5 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAK65940.1 - 0.082 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAK65940.1 - 0.09 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.10 GAK65940.1 - 0.13 11.9 0.3 0.6 9.8 0.0 2.1 1 1 1 2 2 2 0 NTPase NB-ARC PF00931.17 GAK65940.1 - 0.2 10.4 0.0 0.39 9.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Carboxyl_trans PF01039.17 GAK65941.1 - 7e-146 486.4 0.3 9e-146 486.0 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 GAK65941.1 - 0.0055 15.9 0.0 0.36 10.0 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) AAA PF00004.24 GAK65942.1 - 1.9e-17 63.6 0.0 5.7e-17 62.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAK65942.1 - 1.6e-05 25.0 1.2 0.0019 18.3 0.2 3.7 4 1 0 4 4 4 1 AAA domain AAA_5 PF07728.9 GAK65942.1 - 4e-05 23.3 0.4 0.00028 20.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAK65942.1 - 0.00018 22.3 0.0 0.00043 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAK65942.1 - 0.00022 21.2 3.1 0.00048 20.1 0.4 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 GAK65942.1 - 0.00038 20.1 0.3 0.00038 20.1 0.2 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 GAK65942.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAK65942.1 - 0.012 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAK65942.1 - 0.023 13.8 0.0 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAK65942.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAK65942.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 GAK65942.1 - 0.052 12.2 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_2 PF07724.9 GAK65942.1 - 0.081 12.8 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Peptidase_S15 PF02129.13 GAK65943.1 - 5.4e-34 117.8 0.1 8.4e-33 113.9 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAK65943.1 - 2.4e-12 47.1 0.0 7.3e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Zip PF02535.17 GAK65944.1 - 7.6e-43 146.7 2.5 9.6e-43 146.3 1.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_ATPase_C PF00689.16 GAK65944.1 - 0.075 12.5 1.5 0.16 11.5 0.0 2.2 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus ERG4_ERG24 PF01222.12 GAK65946.1 - 1.7e-143 478.2 6.2 2e-143 478.0 4.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 GAK65946.1 - 2.2e-06 27.1 0.3 5.1e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 GAK65946.1 - 6.6e-05 22.9 0.6 0.00023 21.2 0.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 GAK65946.1 - 0.04 14.1 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ORC6 PF05460.8 GAK65946.1 - 4.3 6.3 10.9 5.8 5.9 7.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2012 PF09430.5 GAK65947.1 - 2e-37 127.7 0.0 2.8e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 GAK65947.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Atx10homo_assoc PF09759.4 GAK65948.1 - 1.2e-21 76.3 0.3 1e-18 66.9 0.0 3.6 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain APH PF01636.18 GAK65948.1 - 0.0051 16.5 1.5 0.31 10.7 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Glyco_trans_2_3 PF13632.1 GAK65949.1 - 3.1e-47 160.8 4.7 3.1e-47 160.8 3.3 2.6 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK65949.1 - 6.4e-12 45.7 0.1 4.2e-11 43.0 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAK65949.1 - 0.00016 21.3 0.0 0.0045 16.6 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAK65949.1 - 0.0025 17.1 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 GAK65950.1 - 1.6e-16 60.1 0.5 3.4e-16 59.0 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2404 PF10296.4 GAK65951.1 - 1.5e-07 31.4 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Cyt-b5 PF00173.23 GAK65952.1 - 3.8e-23 81.0 1.7 4.5e-23 80.8 0.0 2.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 GAK65952.1 - 4.6e-10 39.8 17.9 4.6e-10 39.8 12.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PBS_linker_poly PF00427.16 GAK65952.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Lactamase_B_2 PF12706.2 GAK65953.1 - 2.2e-31 108.9 1.8 4e-30 104.8 0.9 2.8 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 GAK65953.1 - 6.8e-13 47.8 0.0 2.6e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 GAK65953.1 - 6.8e-09 35.6 4.2 1.6e-08 34.4 2.9 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Plasmodium_Vir PF05795.6 GAK65955.1 - 1.5 7.9 5.6 11 5.0 0.7 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Cid2 PF09774.4 GAK65955.1 - 2.4 8.2 11.6 0.077 13.0 2.9 2.3 2 0 0 2 2 2 0 Caffeine-induced death protein 2 Dynamin_N PF00350.18 GAK65957.1 - 7.1e-20 71.5 0.0 1.5e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAK65957.1 - 2.5e-05 23.2 0.1 0.00043 19.1 0.0 2.5 2 1 0 2 2 2 1 Dynamin central region AAA_28 PF13521.1 GAK65957.1 - 0.015 15.2 0.2 0.052 13.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAK65957.1 - 0.023 15.1 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 GAK65957.1 - 0.059 13.3 0.1 1.5 8.7 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase GOLGA2L5 PF15070.1 GAK65957.1 - 0.27 9.6 0.1 6.1 5.2 0.0 2.1 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 RCC1 PF00415.13 GAK65958.1 - 2.8e-22 78.6 1.0 0.00058 20.0 0.0 7.0 5 4 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAK65958.1 - 2.9e-15 55.3 20.0 5.4e-05 22.6 0.2 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat DUF2732 PF10809.3 GAK65958.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) KH_1 PF00013.24 GAK65959.1 - 1.9e-38 129.8 9.0 1.8e-16 59.4 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 GAK65959.1 - 2e-29 100.6 10.7 6.2e-10 38.5 1.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 GAK65959.1 - 1.1e-10 40.8 6.5 0.0021 17.5 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 GAK65959.1 - 1.7e-07 30.7 0.2 0.39 10.3 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 GAK65959.1 - 0.0081 15.9 3.2 0.56 10.0 0.1 3.3 3 0 0 3 3 3 1 NusA-like KH domain dUTPase PF00692.14 GAK65959.1 - 0.067 12.6 0.3 0.58 9.6 0.0 2.4 3 0 0 3 3 3 0 dUTPase DUF202 PF02656.10 GAK65960.1 - 3.9e-15 55.8 2.1 6.3e-15 55.1 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Herpes_UL37_2 PF07413.6 GAK65960.1 - 0.0077 15.0 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Betaherpesvirus immediate-early glycoprotein UL37 PgaD PF13994.1 GAK65960.1 - 0.15 11.5 1.0 0.18 11.2 0.1 1.6 2 0 0 2 2 2 0 PgaD-like protein DnaJ PF00226.26 GAK65961.1 - 2.8e-19 68.6 1.6 5.4e-19 67.6 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 GAK65961.1 - 0.037 14.0 0.1 0.06 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 GAK65961.1 - 0.038 13.6 6.6 0.092 12.4 0.5 2.8 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 GAK65961.1 - 0.36 10.9 4.4 0.86 9.7 3.0 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 GAK65961.1 - 0.74 9.3 9.0 2.3 7.8 6.2 1.8 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 GAK65961.1 - 3.9 7.2 9.3 2 8.1 1.4 2.3 1 1 1 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAK65961.1 - 5.3 6.7 9.3 14 5.4 6.4 1.7 1 1 0 1 1 1 0 Glycine zipper PAN_4 PF14295.1 GAK65962.1 - 0.00018 21.1 1.7 0.00036 20.1 1.2 1.5 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 GAK65962.1 - 0.0015 17.7 1.1 0.0038 16.4 0.2 1.9 2 1 0 2 2 2 1 Fringe-like Acyltransferase PF01553.16 GAK65963.1 - 0.00031 20.1 0.0 0.019 14.4 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase FAR1 PF03101.10 GAK65964.1 - 2.2e-06 28.1 0.1 4.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 GAK65964.1 - 0.0068 16.5 0.1 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 GAK65964.1 - 0.028 13.9 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 MuDR family transposase DDE_Tnp_1_6 PF13751.1 GAK65964.1 - 0.053 13.5 0.5 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 Transposase DDE domain zf-CCHC_4 PF14392.1 GAK65964.1 - 0.19 11.4 0.6 0.47 10.1 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle TFIIA PF03153.8 GAK65964.1 - 0.75 9.6 20.3 1.1 9.0 2.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-CCHC PF00098.18 GAK65964.1 - 1.9 8.5 10.0 0.067 13.1 1.9 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF605 PF04652.11 GAK65964.1 - 3.2 7.0 41.7 3.4 6.9 19.0 2.2 2 0 0 2 2 2 0 Vta1 like BPL_LplA_LipB PF03099.14 GAK65967.1 - 5.4e-16 58.7 0.0 8.9e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Opy2 PF09463.5 GAK65968.1 - 0.003 17.5 17.6 0.0046 17.0 12.2 1.3 1 0 0 1 1 1 1 Opy2 protein DUF4381 PF14316.1 GAK65968.1 - 0.068 13.2 1.4 0.11 12.5 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) p450 PF00067.17 GAK65969.1 - 1.5e-75 254.5 0.0 2.1e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.10 GAK65970.1 - 5.3e-131 437.2 39.2 6.1e-131 436.9 27.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1338 PF07063.8 GAK65971.1 - 1.6e-78 263.8 0.0 2.1e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Aldedh PF00171.17 GAK65972.1 - 6.5e-119 397.2 0.1 7.5e-119 397.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK65972.1 - 0.011 14.4 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RRM_6 PF14259.1 GAK65973.1 - 1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK65973.1 - 6.5e-07 28.8 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK65973.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MgsA_C PF12002.3 GAK65974.1 - 1.2e-50 171.4 0.0 4.2e-50 169.7 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 GAK65974.1 - 3.7e-14 53.0 0.0 1.4e-13 51.2 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAK65974.1 - 7.1e-14 51.4 0.0 8.4e-13 47.9 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAK65974.1 - 8.6e-08 32.1 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAK65974.1 - 2.6e-07 30.8 0.7 5.4e-06 26.5 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 GAK65974.1 - 1.2e-06 28.6 2.9 0.00025 21.1 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 GAK65974.1 - 1.6e-06 27.8 0.2 1.2e-05 25.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAK65974.1 - 2.5e-05 23.5 0.2 0.027 13.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 GAK65974.1 - 5.3e-05 23.2 0.0 0.00016 21.7 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 GAK65974.1 - 0.00029 20.2 0.1 0.0043 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAK65974.1 - 0.00033 21.4 0.0 0.0011 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAK65974.1 - 0.00037 20.1 0.3 0.0017 18.0 0.1 2.3 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 GAK65974.1 - 0.00062 20.0 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 GAK65974.1 - 0.0015 18.0 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 GAK65974.1 - 0.0023 18.2 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 GAK65974.1 - 0.0035 17.3 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAK65974.1 - 0.0036 16.8 0.2 1.1 8.5 0.0 2.5 3 0 0 3 3 2 1 AAA-like domain Sgf11 PF08209.6 GAK65974.1 - 0.0043 16.3 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) AAA_30 PF13604.1 GAK65974.1 - 0.0056 16.2 0.9 0.02 14.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAK65974.1 - 0.0095 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 GAK65974.1 - 0.013 15.4 2.9 0.013 15.3 0.2 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 GAK65974.1 - 0.032 13.9 0.1 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 GAK65974.1 - 0.032 13.8 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 GAK65974.1 - 0.033 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 GAK65974.1 - 0.035 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 GAK65974.1 - 0.046 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 GAK65974.1 - 0.055 13.0 0.1 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 GAK65974.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 GAK65974.1 - 0.061 13.0 0.1 4.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase PhoH PF02562.11 GAK65974.1 - 0.097 11.8 0.1 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 GAK65974.1 - 0.17 10.6 0.0 0.39 9.5 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain Rer1 PF03248.8 GAK65975.1 - 2.6e-84 281.1 0.1 3e-84 280.9 0.0 1.0 1 0 0 1 1 1 1 Rer1 family Pyr_redox_2 PF07992.9 GAK65976.1 - 2.1e-20 73.4 0.0 3.6e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK65976.1 - 5.3e-14 52.3 0.0 1.4e-08 34.9 0.0 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 GAK65976.1 - 3.7e-12 44.6 3.2 1e-05 24.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 GAK65976.1 - 2.3e-11 43.6 0.2 7.7e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAK65976.1 - 1.3e-09 37.1 2.8 0.00018 21.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAK65976.1 - 1e-08 34.1 3.2 0.00038 19.6 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 GAK65976.1 - 1.2e-06 28.0 2.6 0.0074 15.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.1 GAK65976.1 - 3.9e-05 23.8 0.0 0.37 10.8 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAK65976.1 - 0.014 15.5 0.6 1 9.6 0.0 2.9 3 0 0 3 3 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 GAK65976.1 - 0.017 14.8 0.0 13 5.5 0.0 3.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding SWIRM PF04433.12 GAK65976.1 - 0.16 12.1 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 SWIRM domain DUF2611 PF11022.3 GAK65977.1 - 2.2e-18 66.1 0.8 8.4e-18 64.2 0.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) Yae1_N PF09811.4 GAK65978.1 - 5.8e-14 51.3 0.9 1.1e-13 50.4 0.6 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ATG16 PF08614.6 GAK65978.1 - 0.031 14.1 1.0 0.084 12.6 0.7 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DJ-1_PfpI PF01965.19 GAK65979.1 - 7.2e-29 100.1 0.0 9e-29 99.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 GAK65979.1 - 5e-17 61.6 0.0 6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 GAK65979.1 - 0.002 17.7 0.1 0.003 17.1 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 GAK65979.1 - 0.0057 16.2 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family TFIIA_gamma_C PF02751.9 GAK65980.1 - 2.5e-23 81.6 0.9 3.3e-23 81.2 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 GAK65980.1 - 5.3e-23 80.3 0.0 8e-23 79.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF2841 PF11001.3 GAK65981.1 - 4.2e-39 133.2 0.2 7.6e-39 132.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) CRAL_TRIO PF00650.15 GAK65982.1 - 1.2e-18 67.0 0.0 1.9e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain adh_short_C2 PF13561.1 GAK65983.1 - 1.9e-17 63.8 0.1 2.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK65983.1 - 9.3e-16 58.1 2.0 9.3e-16 58.1 1.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAK65983.1 - 8.4e-05 22.3 3.3 0.00038 20.1 2.3 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAK65983.1 - 0.012 15.6 0.5 0.025 14.6 0.4 1.6 1 0 0 1 1 1 0 NADH(P)-binding SNF2_N PF00176.18 GAK65984.1 - 5.7e-64 215.7 0.0 7.9e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK65984.1 - 1.2e-12 47.4 0.0 2.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK65984.1 - 3.5e-09 36.3 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 GAK65984.1 - 7.9e-06 24.9 0.1 1.4e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 GAK65984.1 - 0.00023 21.0 0.0 0.00076 19.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PH PF00169.24 GAK65985.1 - 8.9e-08 32.2 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF2664 PF10867.3 GAK65985.1 - 2.6 8.7 6.3 10 6.8 3.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) Glycos_transf_4 PF00953.16 GAK65986.1 - 8.4e-34 116.6 4.9 8.4e-34 116.6 3.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 SKG6 PF08693.5 GAK65986.1 - 0.078 12.3 1.4 8.9 5.7 2.0 3.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TFIIE_alpha PF02002.12 GAK65987.1 - 2.3e-11 43.1 1.7 4.1e-11 42.3 0.7 1.7 2 0 0 2 2 2 1 TFIIE alpha subunit DASH_Dam1 PF08653.5 GAK65987.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 Cupin_8 PF13621.1 GAK65988.1 - 3e-50 171.0 0.1 4.1e-49 167.3 0.1 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 GAK65988.1 - 0.0041 16.3 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein Zn_clus PF00172.13 GAK65989.1 - 9.8e-07 28.5 10.7 9.8e-07 28.5 7.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKD_channel PF08016.7 GAK65990.1 - 0.077 11.4 12.8 0.74 8.1 8.9 2.3 1 1 0 1 1 1 0 Polycystin cation channel Ion_trans PF00520.26 GAK65990.1 - 0.52 9.5 21.7 0.79 8.9 12.4 2.7 1 1 1 2 2 2 0 Ion transport protein UQ_con PF00179.21 GAK65991.1 - 2.4e-46 156.6 0.0 2.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAK65991.1 - 0.0013 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAK65991.1 - 0.0088 15.7 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 GAK65991.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain WH1 PF00568.18 GAK65992.1 - 4.8e-26 90.6 0.0 7e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 GAK65992.1 - 1.6e-08 34.7 0.1 1.6e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain WH2 PF02205.15 GAK65992.1 - 0.0086 15.6 0.9 0.034 13.7 0.6 2.1 1 1 0 1 1 1 1 WH2 motif DCP1 PF06058.8 GAK65992.1 - 0.077 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family Gly-zipper_OmpA PF13436.1 GAK65992.1 - 0.49 10.0 9.1 1.6 8.4 6.3 1.9 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DIOX_N PF14226.1 GAK65993.1 - 2.6e-21 76.2 0.0 4.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAK65993.1 - 3.6e-16 59.2 0.3 7.4e-16 58.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily dCMP_cyt_deam_1 PF00383.17 GAK65994.1 - 1e-12 47.6 0.1 1.9e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 GAK65994.1 - 0.14 11.9 0.4 0.37 10.5 0.1 1.8 1 1 1 2 2 2 0 Xanthomonas XOO_2897-like deaminase Xan_ur_permease PF00860.15 GAK65995.1 - 3.1e-59 200.4 37.8 5.1e-59 199.6 26.1 1.4 1 1 0 1 1 1 1 Permease family ATP1G1_PLM_MAT8 PF02038.11 GAK65995.1 - 7.3 5.6 6.1 0.82 8.7 0.1 2.6 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Ferric_reduct PF01794.14 GAK65996.1 - 5.8e-21 74.8 10.6 5.8e-21 74.8 7.4 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAK65996.1 - 1.9e-16 60.3 0.0 2.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAK65996.1 - 6.8e-14 51.6 0.0 1.9e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 GAK65996.1 - 4.7e-07 30.3 0.0 3.6e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAK65996.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain OAD_gamma PF04277.8 GAK65996.1 - 0.11 12.8 0.0 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ctr PF04145.10 GAK65997.1 - 3.6e-40 137.3 2.1 6.5e-40 136.5 1.5 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.1 GAK65997.1 - 0.016 14.8 3.0 0.068 12.7 0.1 2.1 2 0 0 2 2 2 0 Putative sensor AA_permease PF00324.16 GAK65998.1 - 1e-115 386.8 43.4 1.3e-115 386.5 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAK65998.1 - 1.1e-35 122.9 47.5 1.4e-35 122.6 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease PBP1_TM PF14812.1 GAK65998.1 - 9.7 6.5 7.3 3.1 8.1 2.9 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Alpha-amylase PF00128.19 GAK65999.1 - 1.8e-97 326.5 0.0 2.5e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 GAK65999.1 - 0.002 18.1 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.1 GAK65999.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF543 PF04418.7 GAK66000.1 - 1e-28 99.0 0.2 1e-28 99.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF543) DUF883 PF05957.8 GAK66000.1 - 0.00055 20.2 3.5 0.096 13.0 2.9 2.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) SAGA-Tad1 PF12767.2 GAK66000.1 - 0.028 14.0 0.1 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit MT0933_antitox PF14013.1 GAK66000.1 - 3.1 7.9 14.7 6 7.0 10.2 1.5 1 0 0 1 1 1 0 MT0933-like antitoxin protein ATP-synt_B PF00430.13 GAK66000.1 - 9.8 5.9 10.3 17 5.2 7.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Peroxidase_2 PF01328.12 GAK66001.1 - 1.1e-11 44.0 0.0 1.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 RNase_T PF00929.19 GAK66002.1 - 1.5e-18 67.5 0.1 3.3e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Exonuclease ThylakoidFormat PF11264.3 GAK66002.1 - 0.08 12.5 0.3 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Thylakoid formation protein PINIT PF14324.1 GAK66003.1 - 1.2e-27 96.7 0.0 2.2e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 GAK66003.1 - 8.8e-21 73.1 8.0 1.5e-20 72.4 5.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 GAK66003.1 - 0.00015 21.1 1.7 0.00031 20.1 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 GAK66003.1 - 1.3 8.9 6.8 2.4 8.0 4.7 1.4 1 0 0 1 1 1 0 Ring finger domain Whi5 PF08528.6 GAK66004.1 - 0.22 11.1 0.5 0.38 10.4 0.4 1.4 1 0 0 1 1 1 0 Whi5 like zf-H2C2_2 PF13465.1 GAK66005.1 - 1.6e-08 34.4 0.6 1.6e-08 34.4 0.4 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAK66005.1 - 5.9e-07 29.4 10.7 7.2e-06 26.0 0.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAK66005.1 - 2.6e-05 23.9 2.5 0.14 12.0 0.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 GAK66005.1 - 0.0008 19.5 0.4 0.0008 19.5 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 GAK66005.1 - 0.073 13.3 3.1 4.8 7.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DFP PF04127.10 GAK66006.1 - 9.5e-19 67.7 0.0 9.7e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein AA_permease PF00324.16 GAK66007.1 - 6.3e-112 374.3 35.1 7.7e-112 374.0 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAK66007.1 - 2.1e-34 118.8 38.0 3e-34 118.3 26.3 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3435 PF11917.3 GAK66008.1 - 0.00021 20.1 0.0 0.00057 18.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) CAP_N PF01213.14 GAK66008.1 - 0.36 10.0 3.8 0.87 8.8 2.6 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DSPc PF00782.15 GAK66009.1 - 3.5e-19 68.6 0.3 1.1e-15 57.4 0.5 2.8 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAK66009.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF904 PF06005.7 GAK66009.1 - 0.69 10.2 5.8 1.3 9.4 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) RNB PF00773.14 GAK66011.1 - 2.4e-89 299.8 0.0 3.3e-89 299.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 GAK66011.1 - 7e-09 35.8 1.2 4.1e-08 33.4 0.8 2.3 1 1 0 1 1 1 1 PIN domain OB_RNB PF08206.6 GAK66011.1 - 0.0074 15.7 0.0 0.027 13.9 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease B OB domain DUF572 PF04502.8 GAK66015.1 - 2.4e-43 148.5 0.5 2.7e-43 148.4 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1871 PF08958.5 GAK66015.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) GATA PF00320.22 GAK66017.1 - 2.3e-28 97.2 15.5 5.4e-15 54.4 2.5 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 GAK66017.1 - 2.5e-09 36.5 0.8 5e-09 35.5 0.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 GAK66017.1 - 7.7e-05 21.9 3.5 0.027 13.8 0.4 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 GAK66017.1 - 0.0067 16.2 4.6 0.087 12.6 2.7 2.6 1 1 2 3 3 3 3 Double zinc ribbon Zn-ribbon_8 PF09723.5 GAK66017.1 - 0.052 13.5 0.9 12 5.8 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 GAK66017.1 - 0.072 12.7 3.2 5.6 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-Sec23_Sec24 PF04810.10 GAK66017.1 - 0.097 12.2 4.6 0.13 11.8 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF2413 PF10310.4 GAK66017.1 - 0.21 10.3 4.0 0.4 9.4 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) HypA PF01155.14 GAK66017.1 - 1.7 8.3 2.3 6.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 GAK66017.1 - 2.2 7.6 9.5 1.2 8.4 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbon domain RRN7 PF11781.3 GAK66017.1 - 2.2 7.8 7.7 1.2 8.7 0.6 2.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 TRAPPC-Trs85 PF12739.2 GAK66018.1 - 2.7e-98 329.3 0.1 4.4e-98 328.6 0.1 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Foie-gras_1 PF11817.3 GAK66018.1 - 0.003 17.0 1.2 0.0067 15.9 0.9 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 Glyco_hydro_47 PF01532.15 GAK66019.1 - 1.1e-148 495.6 0.0 1.9e-148 494.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fungal_trans PF04082.13 GAK66020.1 - 4.6e-18 65.0 0.0 8.9e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK66020.1 - 1.9e-07 30.8 8.9 3.6e-07 29.9 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 GAK66020.1 - 0.26 10.8 4.0 0.51 9.8 2.8 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Peptidase_M28 PF04389.12 GAK66022.1 - 4.9e-33 114.3 0.0 1.2e-32 113.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAK66022.1 - 0.00017 21.1 0.0 0.00039 19.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 GAK66022.1 - 0.078 11.7 0.0 0.29 9.8 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SURF4 PF02077.10 GAK66024.1 - 1.5e-93 313.0 4.7 1.7e-93 312.8 3.3 1.0 1 0 0 1 1 1 1 SURF4 family Mito_carr PF00153.22 GAK66025.1 - 4.7e-54 180.0 5.0 3.9e-19 68.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 GAK66026.1 - 9e-69 231.5 0.0 1.7e-68 230.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66026.1 - 2.2e-49 167.8 0.0 3.9e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK66026.1 - 0.00094 18.2 0.0 0.0031 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like BAF1_ABF1 PF04684.8 GAK66026.1 - 7.8 5.2 16.6 16 4.1 11.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor COG2 PF06148.6 GAK66027.1 - 2.8e-37 127.5 1.1 6e-37 126.4 0.2 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 GAK66027.1 - 2.9e-07 30.6 0.0 0.00011 22.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3510) Vps51 PF08700.6 GAK66027.1 - 0.017 14.9 0.1 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 Vps51/Vps67 Tombus_movement PF05318.7 GAK66027.1 - 0.16 12.6 1.8 0.29 11.7 0.4 2.2 2 0 0 2 2 2 0 Tombusvirus movement protein adh_short PF00106.20 GAK66028.1 - 5.2e-20 72.0 1.4 9e-14 51.7 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAK66028.1 - 3.4e-12 46.4 0.9 1.8e-10 40.7 0.1 2.3 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAK66028.1 - 2e-06 27.9 1.0 5.4e-06 26.5 0.7 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 GAK66028.1 - 5e-05 22.4 0.0 7.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 GAK66028.1 - 0.001 19.4 0.3 0.0029 18.0 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.1 GAK66028.1 - 0.0013 18.5 0.1 0.0024 17.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 GAK66028.1 - 0.0016 17.5 0.1 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 GAK66028.1 - 0.0037 16.7 0.1 0.0066 15.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAK66028.1 - 0.0043 16.7 0.3 0.0077 15.8 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 GAK66028.1 - 0.016 14.8 0.1 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_2 PF03446.10 GAK66028.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Helicase_RecD PF05127.9 GAK66028.1 - 0.028 14.0 0.2 0.049 13.2 0.2 1.3 1 0 0 1 1 1 0 Helicase Polysacc_synt_2 PF02719.10 GAK66028.1 - 0.035 12.9 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAK66028.1 - 0.049 13.4 0.5 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 GAK66028.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase La PF05383.12 GAK66029.1 - 6.5e-19 67.4 0.0 2.5e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 GAK66029.1 - 7.6e-08 31.8 0.2 2.4e-07 30.2 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66029.1 - 6.3e-07 29.2 0.1 2.2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAK66029.1 - 2.6e-05 24.0 0.2 0.0048 16.7 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.1 GAK66029.1 - 0.0014 18.3 0.1 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb5_N PF03871.9 GAK66029.1 - 0.038 14.3 0.2 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Dabb PF07876.7 GAK66029.1 - 0.088 13.2 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF3149 PF11346.3 GAK66030.1 - 0.038 13.5 1.1 0.066 12.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Pro_isomerase PF00160.16 GAK66031.1 - 1.5e-47 161.7 0.2 1.7e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank PF00023.25 GAK66032.1 - 3.3e-21 73.9 5.6 2.8e-08 33.1 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 GAK66032.1 - 1e-20 73.6 1.3 9.7e-14 51.4 0.4 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAK66032.1 - 2.1e-19 69.6 0.5 2.2e-14 53.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAK66032.1 - 3.4e-17 62.0 4.2 5.3e-10 39.2 0.2 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK66032.1 - 8.2e-15 53.4 4.8 0.00075 19.5 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat IDO PF01231.13 GAK66033.1 - 1.3e-40 139.2 0.0 2e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Chorismate_bind PF00425.13 GAK66034.1 - 2.6e-75 253.0 0.0 4.1e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 GAK66034.1 - 2.7e-33 115.0 0.0 8.4e-23 80.8 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 GAK66034.1 - 4.5e-16 59.1 0.0 2e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 GAK66034.1 - 2.7e-08 33.5 0.0 4.7e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 ERAP1_C PF11838.3 GAK66035.1 - 0.0011 18.2 0.5 0.015 14.5 0.1 2.4 2 0 0 2 2 2 1 ERAP1-like C-terminal domain TPR_14 PF13428.1 GAK66035.1 - 1 10.1 11.2 13 6.7 0.3 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M24 PF00557.19 GAK66037.1 - 1.9e-42 145.1 0.0 2.9e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 GAK66037.1 - 2.4e-23 83.0 0.0 1.3e-21 77.4 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain AdoHcyase PF05221.12 GAK66038.1 - 4.2e-136 452.1 0.0 4.8e-136 451.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 GAK66038.1 - 4.3e-85 283.5 3.3 6.3e-85 282.9 2.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAK66038.1 - 1.6e-10 40.4 0.0 3.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 GAK66038.1 - 0.00031 20.1 0.1 0.00048 19.5 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 GAK66038.1 - 0.0018 18.2 0.1 0.004 17.1 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 GAK66038.1 - 0.042 12.9 0.5 0.2 10.7 0.4 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4448 PF14610.1 GAK66038.1 - 0.052 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) NAD_binding_7 PF13241.1 GAK66038.1 - 0.08 13.2 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Septin PF00735.13 GAK66039.1 - 6.4e-125 415.8 0.8 1.1e-124 415.0 0.5 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 GAK66039.1 - 2.7e-07 30.5 0.0 6.6e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAK66039.1 - 2.3e-06 26.9 0.0 6.3e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAK66039.1 - 0.00011 22.1 3.9 0.065 13.0 0.0 3.2 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 GAK66039.1 - 0.00013 21.4 0.3 0.0024 17.3 0.0 2.8 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Ras PF00071.17 GAK66039.1 - 0.00032 20.1 1.4 0.0044 16.4 0.0 2.7 2 1 0 2 2 2 1 Ras family AAA_10 PF12846.2 GAK66039.1 - 0.0013 18.2 0.1 0.0043 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 GAK66039.1 - 0.0019 18.3 0.2 0.014 15.5 0.0 2.4 3 1 0 3 3 3 1 AAA domain AIG1 PF04548.11 GAK66039.1 - 0.0023 17.0 0.8 0.0051 15.9 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Arch_ATPase PF01637.13 GAK66039.1 - 0.0031 17.2 1.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 GAK66039.1 - 0.0041 17.4 7.8 0.016 15.5 0.7 2.6 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 GAK66039.1 - 0.0067 16.9 0.1 0.06 13.8 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 GAK66039.1 - 0.011 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAK66039.1 - 0.022 14.7 0.2 0.097 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 GAK66039.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 GAK66039.1 - 0.054 13.0 0.4 0.13 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 GAK66039.1 - 0.092 12.2 0.3 9.6 5.6 0.0 3.1 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Phage_GPO PF05929.6 GAK66039.1 - 0.15 11.3 4.3 0.29 10.3 3.0 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YlqD PF11068.3 GAK66039.1 - 0.21 11.6 7.2 0.51 10.3 5.0 1.7 1 0 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.10 GAK66039.1 - 0.39 9.8 9.4 0.24 10.5 5.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.12 GAK66039.1 - 0.39 10.2 2.5 19 4.6 0.0 3.2 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein IncA PF04156.9 GAK66039.1 - 0.4 10.2 7.6 0.76 9.3 5.3 1.4 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 GAK66039.1 - 5.5 7.2 12.7 1.3e+02 2.7 8.8 2.3 1 1 0 1 1 1 0 AAA domain Tht1 PF04163.7 GAK66040.1 - 2e-06 26.5 1.3 2.5e-06 26.2 0.4 1.3 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Stork_head PF10264.4 GAK66040.1 - 0.15 12.2 0.1 0.64 10.2 0.0 2.1 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain MRG PF05712.8 GAK66041.1 - 6.7e-54 181.7 0.0 1.8e-53 180.3 0.0 1.6 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 GAK66041.1 - 1.5e-09 37.3 0.9 2.5e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 GAK66041.1 - 0.081 12.6 2.7 0.13 11.9 0.9 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain AMP-binding PF00501.23 GAK66042.1 - 2.1e-82 276.7 0.0 3e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sec63 PF02889.11 GAK66043.1 - 7.2e-184 610.1 0.0 3.5e-97 325.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 GAK66043.1 - 7.8e-51 171.9 0.0 5.7e-28 97.5 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 GAK66043.1 - 1.2e-14 54.5 0.0 7.1e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAK66043.1 - 2.3e-12 46.5 0.0 4.9e-08 32.7 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAK66043.1 - 7.3e-06 26.1 0.0 0.0031 17.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK66043.1 - 0.0029 17.3 0.0 0.11 12.2 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 GAK66043.1 - 0.011 15.0 0.0 0.26 10.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein PHD PF00628.24 GAK66044.1 - 3.3e-07 29.8 14.2 5.6e-07 29.1 9.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAK66044.1 - 0.0013 18.0 6.6 0.0024 17.1 4.6 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 GAK66044.1 - 0.091 13.0 0.0 0.091 13.0 0.0 5.4 3 2 0 3 3 3 0 SET domain RNA_pol_3_Rpc31 PF11705.3 GAK66045.1 - 3.4e-06 27.1 7.2 6.8e-06 26.1 5.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 HEAT_2 PF13646.1 GAK66045.1 - 0.0003 21.0 22.1 0.00037 20.7 0.2 6.3 5 2 0 5 5 5 2 HEAT repeats Anticodon_1 PF08264.8 GAK66045.1 - 0.0074 16.0 0.0 0.03 14.0 0.0 2.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA BSP_II PF05432.6 GAK66045.1 - 0.009 15.3 10.4 0.015 14.5 7.2 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) FLO_LFY PF01698.11 GAK66045.1 - 0.029 13.2 8.1 0.052 12.3 5.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Pox_Ag35 PF03286.9 GAK66045.1 - 0.14 11.6 13.8 0.32 10.4 9.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.13 GAK66045.1 - 0.37 9.9 9.2 1.5 7.9 5.2 2.2 2 0 0 2 2 2 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.7 GAK66045.1 - 1.1 8.8 16.8 0.19 11.4 8.7 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.6 GAK66045.1 - 1.5 8.5 12.7 6.1 6.6 7.7 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Cut8_N PF14482.1 GAK66045.1 - 2.1 8.4 5.1 5.5 7.0 3.5 1.7 1 0 0 1 1 1 0 Cut8 proteasome-binding domain PBP1_TM PF14812.1 GAK66045.1 - 3.4 8.0 20.1 11 6.3 13.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 GAK66045.1 - 5.8 6.0 11.5 9.3 5.3 8.0 1.3 1 0 0 1 1 1 0 NOA36 protein TLP-20 PF06088.6 GAK66045.1 - 6.4 6.4 8.2 1.4 8.5 2.8 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) zf-MYND PF01753.13 GAK66046.1 - 2.1e-12 46.6 9.0 2.1e-12 46.6 6.2 3.1 3 1 0 3 3 3 1 MYND finger SET PF00856.23 GAK66046.1 - 4.1e-10 40.2 0.0 9.9e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-Mss51 PF13824.1 GAK66046.1 - 0.049 13.4 8.6 1.1 9.1 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Aminotran_1_2 PF00155.16 GAK66048.1 - 1.5e-35 122.8 0.0 3.5e-35 121.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Myotoxins PF00819.12 GAK66048.1 - 0.13 12.3 0.1 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Myotoxin Aminotran_MocR PF12897.2 GAK66048.1 - 0.44 9.0 2.0 9.6 4.6 0.0 2.4 3 0 0 3 3 3 0 Alanine-glyoxylate amino-transferase CHCH PF06747.8 GAK66049.1 - 6e-09 35.5 3.4 8.9e-09 35.0 2.4 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 GAK66049.1 - 0.011 15.7 3.2 0.032 14.2 2.2 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Copper-fist PF00649.13 GAK66049.1 - 0.04 13.1 0.6 0.07 12.3 0.4 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain Cmc1 PF08583.5 GAK66049.1 - 0.06 13.1 3.7 0.63 9.8 2.7 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3991 PF13154.1 GAK66049.1 - 0.086 13.0 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) UPF0203 PF05254.7 GAK66049.1 - 0.35 10.7 2.6 1.3 8.9 0.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 GAK66049.1 - 1.3 9.0 5.3 7.4 6.6 0.6 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Actin PF00022.14 GAK66050.1 - 4.1e-36 124.2 0.0 9.6e-36 123.0 0.0 1.5 1 1 0 1 1 1 1 Actin CN_hydrolase PF00795.17 GAK66057.1 - 3.6e-12 46.0 0.0 1.4e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase BolA PF01722.13 GAK66058.1 - 1.1e-19 70.1 0.0 2.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 BolA-like protein Adeno_Penton_B PF01686.12 GAK66058.1 - 0.067 11.4 0.0 0.087 11.0 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein PT-VENN PF04829.8 GAK66058.1 - 0.4 10.2 0.1 0.4 10.2 0.1 2.1 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif UvrD-helicase PF00580.16 GAK66059.1 - 1.3e-14 54.2 0.0 6.7e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 GAK66059.1 - 7.3e-12 45.4 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 GAK66059.1 - 1.9e-10 40.7 0.0 5.3e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 GAK66059.1 - 1.7e-08 34.2 0.4 0.093 12.2 0.0 3.6 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 GAK66059.1 - 1.5e-07 31.1 1.3 0.002 17.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 GAK66059.1 - 4.3e-06 26.3 0.4 0.00015 21.4 0.0 3.5 4 0 0 4 4 4 1 Part of AAA domain AAA_22 PF13401.1 GAK66059.1 - 0.00015 21.8 0.1 0.14 12.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 GAK66059.1 - 0.0007 18.8 0.0 0.077 12.2 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_12 PF13087.1 GAK66059.1 - 0.015 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4050 PF13259.1 GAK66059.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Cyclin_N PF00134.18 GAK66061.1 - 1.2e-45 154.2 0.4 7.7e-43 145.0 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAK66061.1 - 2.1e-32 111.5 0.2 2.1e-32 111.5 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain JAB PF01398.16 GAK66062.1 - 1.7e-28 98.6 0.1 3.4e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 GAK66062.1 - 9.7e-07 28.3 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 GAK66062.1 - 0.029 13.8 0.5 0.055 12.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DSPc PF00782.15 GAK66063.1 - 0.0002 20.9 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAK66063.1 - 0.00029 20.8 0.0 0.00079 19.5 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 GAK66063.1 - 0.0047 17.1 0.2 0.035 14.3 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 GAK66063.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Aldedh PF00171.17 GAK66065.1 - 2.6e-119 398.5 0.1 3.1e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Viral_env_E26 PF11050.3 GAK66065.1 - 0.01 15.0 0.0 0.033 13.3 0.0 1.8 2 0 0 2 2 2 0 Virus envelope protein E26 WD40 PF00400.27 GAK66066.1 - 1.3e-30 104.1 3.0 4.2e-06 26.4 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAK66066.1 - 0.038 13.4 0.0 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Pyr_redox_2 PF07992.9 GAK66067.1 - 1.3e-28 100.2 0.1 2.2e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK66067.1 - 6.3e-18 64.9 0.6 4.5e-15 55.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK66067.1 - 3.8e-08 33.6 0.6 0.00053 20.0 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK66067.1 - 1.6e-05 24.1 0.1 0.0002 20.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 GAK66067.1 - 2.8e-05 24.0 0.1 0.001 19.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAK66067.1 - 0.00011 21.4 0.2 0.16 11.0 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK66067.1 - 0.00027 19.8 0.6 0.012 14.4 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 GAK66067.1 - 0.00069 18.5 2.5 0.012 14.5 0.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 GAK66067.1 - 0.0019 17.1 0.5 0.012 14.4 0.0 2.4 2 2 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAK66067.1 - 0.0032 16.4 0.0 0.038 12.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 GAK66067.1 - 0.0039 17.4 0.4 0.096 12.9 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.9 GAK66067.1 - 0.0075 14.7 0.3 0.026 13.0 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 GAK66067.1 - 0.012 14.3 0.1 0.094 11.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 GAK66067.1 - 0.02 14.9 0.2 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 GAK66067.1 - 0.034 13.1 1.9 0.11 11.4 0.1 2.4 2 1 0 2 2 2 0 FAD binding domain Glyco_transf_4 PF13439.1 GAK66067.1 - 0.09 12.4 1.1 0.22 11.2 0.8 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DEAD PF00270.24 GAK66068.1 - 6.1e-33 113.6 0.9 3.4e-32 111.2 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK66068.1 - 2e-26 91.6 0.2 3.6e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.9 GAK66068.1 - 8.4e-05 22.3 0.1 0.00021 21.0 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain Helicase_C_2 PF13307.1 GAK66068.1 - 0.00061 19.7 0.0 0.0023 17.8 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_30 PF13604.1 GAK66068.1 - 0.0039 16.7 0.1 0.03 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain CDC27 PF09507.5 GAK66069.1 - 1.2e-80 271.8 60.5 1.8e-79 268.0 41.9 2.3 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Gcd10p PF04189.8 GAK66071.1 - 1.1e-87 293.9 0.0 4e-87 292.1 0.0 1.7 2 0 0 2 2 2 1 Gcd10p family Lin-8 PF03353.10 GAK66072.1 - 0.038 13.2 7.5 0.046 13.0 5.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2052 PF09747.4 GAK66072.1 - 0.38 10.6 7.6 0.49 10.2 5.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TEX19 PF15553.1 GAK66072.1 - 0.44 10.3 3.5 0.55 10.0 2.4 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 Ku_C PF03730.9 GAK66072.1 - 0.49 10.9 5.2 1 9.9 3.6 1.6 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm UBN_AB PF14075.1 GAK66072.1 - 0.86 9.2 5.3 0.13 11.8 0.7 1.7 1 1 1 2 2 2 0 Ubinuclein conserved middle domain DUF2201_N PF13203.1 GAK66072.1 - 0.95 8.5 6.0 1.1 8.4 4.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.10 GAK66072.1 - 1.5 7.4 7.5 1.7 7.2 5.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 GAK66072.1 - 2 7.7 12.0 2.4 7.4 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 GAK66072.1 - 5.3 5.7 6.3 6.5 5.4 4.4 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.9 GAK66072.1 - 5.4 4.9 10.6 6.2 4.7 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 GAK66072.1 - 7.8 6.4 11.2 10 6.0 7.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ssu72 PF04722.8 GAK66073.1 - 7.3e-77 257.1 0.0 8.7e-77 256.8 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 GAK66073.1 - 0.013 15.8 0.3 0.047 14.0 0.1 1.9 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Ras PF00071.17 GAK66074.1 - 1.1e-53 180.9 0.0 1.3e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK66074.1 - 1.9e-15 57.3 0.0 3.6e-15 56.5 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAK66074.1 - 4.1e-07 29.4 0.0 7.2e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAK66074.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 GAK66074.1 - 0.11 11.9 0.3 1.2 8.6 0.2 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MerR-DNA-bind PF09278.6 GAK66075.1 - 0.0045 17.3 2.1 0.44 10.9 0.1 3.1 2 0 0 2 2 2 2 MerR, DNA binding TPR_2 PF07719.12 GAK66075.1 - 0.15 12.0 1.2 9 6.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.24 GAK66076.1 - 2.5e-42 144.2 0.0 6.4e-42 142.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK66076.1 - 8e-24 83.3 0.0 2.4e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAK66076.1 - 2.3e-05 23.3 0.0 4.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAK66076.1 - 0.00048 20.0 0.4 0.004 16.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAK66076.1 - 3.4 6.6 8.1 0.88 8.5 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Acyl-CoA_dh_1 PF00441.19 GAK66077.1 - 1e-31 110.0 1.2 1.5e-31 109.5 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAK66077.1 - 7.8e-17 60.5 0.2 1.3e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAK66077.1 - 4e-11 43.4 0.0 1.7e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAK66077.1 - 4.2e-09 36.7 0.8 6.2e-09 36.2 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_transf_8 PF01501.15 GAK66078.1 - 7.5e-15 54.9 0.0 1.7e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 SUZ PF12752.2 GAK66079.1 - 1.1e-14 54.7 5.4 1.1e-14 54.7 3.7 4.0 3 2 0 3 3 3 1 SUZ domain R3H PF01424.17 GAK66079.1 - 1.5e-08 34.1 0.4 4e-08 32.8 0.3 1.7 1 0 0 1 1 1 1 R3H domain UCH PF00443.24 GAK66080.1 - 1.2e-43 149.2 0.0 1.8e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK66080.1 - 4.5e-10 39.4 0.0 2.9e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TrbE PF11100.3 GAK66081.1 - 0.25 11.2 1.7 0.5 10.2 1.1 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbE NAD_binding_1 PF00175.16 GAK66082.1 - 5e-26 91.4 0.0 1.1e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAK66082.1 - 2.2e-19 69.4 0.0 4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAK66082.1 - 5.3e-05 23.1 0.0 0.00037 20.4 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAK66082.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain ABC_tran PF00005.22 GAK66083.1 - 1.8e-46 157.8 0.1 1.3e-21 77.3 0.0 3.3 3 1 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 GAK66083.1 - 2.3e-24 85.0 4.1 2.3e-24 85.0 2.9 3.8 4 1 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 GAK66083.1 - 3.8e-17 63.1 0.1 0.0015 18.5 0.0 4.5 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 GAK66083.1 - 6e-11 41.9 0.2 0.0013 17.9 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAK66083.1 - 1.5e-08 34.0 0.4 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAK66083.1 - 2.6e-08 34.6 0.7 0.0091 16.8 0.0 4.4 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 GAK66083.1 - 5.4e-08 32.7 0.0 0.0026 17.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.1 GAK66083.1 - 1.5e-06 28.4 0.4 0.15 12.2 0.0 3.9 4 1 0 4 4 3 2 AAA domain NACHT PF05729.7 GAK66083.1 - 1.7e-06 27.8 0.2 0.0035 17.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 GAK66083.1 - 2.8e-06 27.8 0.0 0.07 13.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 GAK66083.1 - 3.8e-06 26.4 0.0 0.024 14.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 GAK66083.1 - 6.2e-06 25.8 0.9 0.03 13.7 0.0 3.5 3 0 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 GAK66083.1 - 8.3e-06 25.0 0.0 0.063 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAK66083.1 - 2.9e-05 24.1 5.2 0.019 14.9 0.4 3.3 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.1 GAK66083.1 - 6.8e-05 23.1 0.7 1.5 9.1 0.0 3.9 4 0 0 4 4 3 2 AAA domain MobB PF03205.9 GAK66083.1 - 8e-05 22.3 0.0 0.07 12.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAK66083.1 - 0.00024 20.9 0.0 0.96 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAK66083.1 - 0.00064 19.8 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 GAK66083.1 - 0.00084 19.2 4.4 0.45 10.4 0.0 3.9 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 GAK66083.1 - 0.00092 19.4 0.1 0.3 11.2 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 GAK66083.1 - 0.0012 18.8 6.8 0.14 12.0 0.2 3.4 3 0 0 3 3 3 2 AAA domain ArgK PF03308.11 GAK66083.1 - 0.0019 17.0 0.2 1.4 7.6 0.0 2.6 2 0 0 2 2 2 2 ArgK protein Gly-zipper_OmpA PF13436.1 GAK66083.1 - 0.0034 17.0 7.1 0.0083 15.7 4.9 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain FtsK_SpoIIIE PF01580.13 GAK66083.1 - 0.0088 15.5 0.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MutS_V PF00488.16 GAK66083.1 - 0.018 14.4 0.1 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 MutS domain V DUF87 PF01935.12 GAK66083.1 - 0.023 14.5 4.4 0.12 12.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_23 PF13476.1 GAK66083.1 - 0.029 14.7 0.0 0.029 14.7 0.0 4.7 4 1 0 5 5 4 0 AAA domain Dynamin_N PF00350.18 GAK66083.1 - 0.038 13.8 3.9 0.61 9.8 0.0 3.3 4 0 0 4 4 4 0 Dynamin family AAA_15 PF13175.1 GAK66083.1 - 0.041 12.9 0.7 12 4.7 0.0 3.3 4 0 0 4 4 3 0 AAA ATPase domain NB-ARC PF00931.17 GAK66083.1 - 0.051 12.4 0.4 7.1 5.3 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 GAK66083.1 - 0.064 12.7 0.1 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 GAK66083.1 - 0.069 12.7 0.3 2.5 7.6 0.0 2.8 2 1 1 3 3 3 0 AAA domain Arch_ATPase PF01637.13 GAK66083.1 - 0.089 12.4 0.5 16 5.0 0.0 2.9 3 0 0 3 3 2 0 Archaeal ATPase NTPase_1 PF03266.10 GAK66083.1 - 0.098 12.3 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 GAK66083.1 - 0.12 11.8 0.0 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 GAK66083.1 - 0.23 11.3 10.8 0.3 10.9 0.0 3.6 4 1 0 4 4 3 0 AAA domain AAA_5 PF07728.9 GAK66083.1 - 0.91 9.2 4.1 15 5.2 0.0 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) Cyclase PF04199.8 GAK66084.1 - 5.6e-13 48.9 0.1 1.3e-12 47.7 0.1 1.6 1 1 0 1 1 1 1 Putative cyclase Mur_ligase_M PF08245.7 GAK66085.1 - 1.9e-06 28.0 0.0 5.1e-05 23.3 0.0 2.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 GAK66085.1 - 0.041 13.9 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain R3H PF01424.17 GAK66086.1 - 1.1e-12 47.4 0.1 2.7e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 GAK66086.1 - 3.8e-11 42.8 0.0 7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK66086.1 - 2.5e-08 33.4 0.0 5.6e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66086.1 - 3.9e-05 23.4 0.0 6.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2414 PF10309.4 GAK66087.1 - 4.1e-09 35.9 0.0 6.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) BTB PF00651.26 GAK66088.1 - 7.3e-10 38.8 0.2 0.00034 20.5 0.0 3.5 3 1 0 3 3 3 3 BTB/POZ domain SLX9 PF15341.1 GAK66088.1 - 0.14 12.6 2.6 0.14 12.6 0.5 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 WD40 PF00400.27 GAK66089.1 - 7.6e-49 161.9 2.4 1.4e-09 37.4 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 GAK66089.1 - 8.8e-46 155.5 0.1 8.8e-46 155.5 0.0 3.6 2 2 0 3 3 3 1 Striatin family Nucleoporin_N PF08801.6 GAK66089.1 - 6e-06 25.2 0.0 0.016 14.0 0.0 3.3 3 0 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 GAK66089.1 - 0.00074 17.7 1.8 0.21 9.6 0.0 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PAN_3 PF08277.7 GAK66089.1 - 0.0077 15.8 0.0 0.025 14.2 0.0 1.8 1 0 0 1 1 1 1 PAN-like domain Sulfate_transp PF00916.15 GAK66090.1 - 4.1e-42 144.1 2.1 7.6e-42 143.2 1.4 1.5 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 GAK66090.1 - 1.9e-14 53.2 0.0 3.9e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 GAK66090.1 - 4e-08 32.6 0.0 7.9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain Med26 PF08711.6 GAK66091.1 - 1.7e-07 30.6 0.0 4.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF1903 PF08991.5 GAK66092.1 - 4.8e-29 100.3 4.9 5.6e-29 100.0 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 GAK66092.1 - 0.33 10.9 5.3 0.52 10.2 3.7 1.4 1 0 0 1 1 1 0 CHCH domain Herpes_UL6 PF01763.11 GAK66094.1 - 0.0059 14.8 0.4 0.012 13.8 0.3 1.4 1 0 0 1 1 1 1 Herpesvirus UL6 like Abhydrolase_5 PF12695.2 GAK66095.1 - 2.6e-08 33.7 0.0 2.1e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAK66095.1 - 7.4e-05 21.6 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAK66095.1 - 0.0012 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAK66095.1 - 0.0053 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAK66095.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase R3H PF01424.17 GAK66096.1 - 5.5e-13 48.4 0.0 1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain AFOR_N PF02730.10 GAK66096.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain HSP70 PF00012.15 GAK66097.1 - 2.4e-267 887.7 8.1 2.7e-267 887.5 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAK66097.1 - 4.5e-16 58.3 0.2 2.8e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 GAK66097.1 - 0.0026 16.9 0.1 0.016 14.3 0.0 2.4 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 GAK66097.1 - 0.0074 16.1 1.5 0.12 12.2 0.1 3.3 2 1 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.11 GAK66097.1 - 0.0084 15.7 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RNA_pol PF00940.14 GAK66097.1 - 0.11 10.9 1.2 0.2 10.0 0.8 1.4 1 0 0 1 1 1 0 DNA-dependent RNA polymerase FlxA PF14282.1 GAK66097.1 - 8.2 6.4 12.1 0.25 11.3 0.6 2.4 1 1 1 2 2 2 0 FlxA-like protein WD40 PF00400.27 GAK66098.1 - 1.8e-17 62.4 11.4 2.4e-05 24.0 0.0 7.1 7 1 0 7 7 7 3 WD domain, G-beta repeat DUF3639 PF12341.3 GAK66098.1 - 4.6e-05 23.3 1.6 0.0067 16.3 0.1 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3639) eIF2A PF08662.6 GAK66098.1 - 0.096 12.3 0.0 1.5 8.4 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A SAGA-Tad1 PF12767.2 GAK66099.1 - 4.2e-50 170.7 2.0 2.6e-49 168.1 0.2 2.6 2 1 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit BRCT PF00533.21 GAK66101.1 - 0.0033 17.5 0.0 0.0084 16.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 GAK66103.1 - 1.2e-41 142.6 0.2 3.1e-23 82.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66103.1 - 8.1e-11 41.4 0.2 1.6e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAK66103.1 - 0.32 9.7 0.1 0.46 9.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 GAK66103.1 - 0.33 10.2 0.1 0.59 9.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family tRNA-synt_1b PF00579.20 GAK66105.1 - 1.2e-21 77.0 0.0 1.3e-20 73.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3860 PF12976.2 GAK66105.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) LSM PF01423.17 GAK66106.1 - 7.4e-12 44.6 0.0 1.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAK66106.1 - 5.2e-05 23.0 0.0 6.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain TAF PF02969.12 GAK66107.1 - 4.8e-27 93.7 0.4 9e-27 92.8 0.3 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 GAK66107.1 - 1.6e-12 47.3 0.0 5.3e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 GAK66107.1 - 6.9e-06 26.0 0.8 1.3e-05 25.2 0.5 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MSP1_C PF07462.6 GAK66107.1 - 0.0062 14.9 1.0 0.01 14.2 0.7 1.3 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus TFIID-31kDa PF02291.10 GAK66107.1 - 0.056 13.2 1.6 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF3306 PF11748.3 GAK66107.1 - 0.09 13.4 1.4 0.29 11.7 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Tubulin PF00091.20 GAK66108.1 - 7.4e-75 251.4 0.0 1.6e-74 250.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAK66108.1 - 5.2e-44 149.3 0.0 9.7e-44 148.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAK66108.1 - 6.2e-07 29.4 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAK66108.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Fibrillarin PF01269.12 GAK66110.1 - 8e-108 358.6 0.0 1e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 GAK66110.1 - 9.9e-06 25.2 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 GAK66110.1 - 0.0099 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAK66110.1 - 0.053 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Avl9 PF09794.4 GAK66111.1 - 1.4e-140 468.0 0.0 1.8e-140 467.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 GAK66111.1 - 1.1e-10 41.2 0.0 6.1e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 GAK66111.1 - 2.7e-10 39.9 0.0 4.4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.7 GAK66111.1 - 5.1e-05 23.3 0.2 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking uDENN PF03456.13 GAK66111.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 uDENN domain IATP PF04568.7 GAK66111.1 - 6.1 6.9 6.0 3.9 7.5 1.8 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Thaumatin PF00314.12 GAK66113.1 - 2.1e-05 24.0 0.2 2.9e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Thaumatin family CENP-H PF05837.7 GAK66115.1 - 6.2e-08 32.7 2.3 6.2e-08 32.7 1.6 2.7 2 2 1 3 3 3 1 Centromere protein H (CENP-H) PIP5K PF01504.13 GAK66116.1 - 4.5e-84 281.4 0.0 6.6e-84 280.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ras PF00071.17 GAK66117.1 - 1e-31 109.5 0.0 1.6e-29 102.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAK66117.1 - 1.5e-13 51.2 0.0 3.7e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK66117.1 - 2.1e-07 30.3 0.0 4.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAK66117.1 - 0.00015 21.0 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAK66117.1 - 0.00055 19.4 0.0 0.0086 15.5 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAK66117.1 - 0.0026 17.7 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAK66117.1 - 0.038 13.2 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Glucosamine_iso PF01182.15 GAK66118.1 - 7.3e-66 221.6 0.0 9.2e-66 221.3 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Na_H_Exchanger PF00999.16 GAK66119.1 - 1.8e-62 211.0 36.3 1.8e-62 211.0 25.2 1.7 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family DUF4366 PF14283.1 GAK66119.1 - 0.047 13.1 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2574 PF10836.3 GAK66119.1 - 0.11 12.2 1.0 0.33 10.6 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Nic96 PF04097.9 GAK66120.1 - 1.2e-183 611.6 0.4 1.7e-183 611.1 0.2 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Cation_efflux PF01545.16 GAK66121.1 - 1.8e-31 109.3 2.9 2.2e-31 109.0 2.0 1.1 1 0 0 1 1 1 1 Cation efflux family tRNA-synt_2b PF00587.20 GAK66122.1 - 1e-43 148.9 0.0 1.5e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAK66122.1 - 1.3e-12 47.4 0.1 5.2e-12 45.5 0.1 2.0 1 1 0 1 1 1 1 Anticodon binding domain RNA12 PF10443.4 GAK66123.1 - 1.2e-144 481.9 0.4 1.6e-144 481.5 0.3 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 GAK66123.1 - 4.5e-06 26.1 0.0 4.4e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 GAK66123.1 - 9.7e-05 22.1 0.0 0.00034 20.3 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 GAK66123.1 - 0.00042 20.3 2.1 0.0099 15.8 0.7 3.2 2 1 0 2 2 2 1 AAA ATPase domain RRM_5 PF13893.1 GAK66123.1 - 0.00054 19.7 0.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 GAK66123.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RRM_6 PF14259.1 GAK66123.1 - 0.024 14.6 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NB-ARC PF00931.17 GAK66123.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SAP25 PF15476.1 GAK66124.1 - 0.15 11.5 0.9 0.32 10.4 0.6 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 JTB PF05439.7 GAK66125.1 - 0.00092 18.9 3.2 0.0046 16.7 0.4 2.2 1 1 1 2 2 2 2 Jumping translocation breakpoint protein (JTB) Mito_carr PF00153.22 GAK66126.1 - 9.8e-05 21.9 0.6 0.0024 17.5 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial carrier protein Clathrin PF00637.15 GAK66127.1 - 1.9e-12 46.9 0.1 0.00021 20.9 0.0 3.3 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-RING_5 PF14634.1 GAK66127.1 - 0.0091 15.7 5.9 0.016 14.9 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAK66127.1 - 0.033 14.2 5.7 0.057 13.4 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK66127.1 - 0.12 12.2 7.0 0.23 11.3 4.9 1.5 1 0 0 1 1 1 0 Ring finger domain HypA PF01155.14 GAK66127.1 - 0.13 11.9 0.5 0.59 9.8 0.5 1.9 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 GAK66127.1 - 0.3 10.8 5.6 0.55 10.0 3.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.2 GAK66127.1 - 4.5 7.4 7.2 2.5 8.2 3.5 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger DUF2946 PF11162.3 GAK66130.1 - 0.035 14.3 4.5 0.067 13.3 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SOR_SNZ PF01680.12 GAK66132.1 - 3e-112 373.2 5.3 4.3e-112 372.7 3.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 GAK66132.1 - 2.8e-06 26.5 9.4 5.1e-06 25.7 0.1 2.9 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NanE PF04131.9 GAK66132.1 - 0.006 15.5 0.3 0.082 11.8 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 GAK66132.1 - 0.008 15.2 0.0 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 GAK66132.1 - 0.02 14.0 0.2 0.02 14.0 0.1 2.3 2 1 1 3 3 3 0 Nitronate monooxygenase Dus PF01207.12 GAK66132.1 - 0.033 13.0 0.3 0.71 8.6 0.0 2.3 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 GAK66132.1 - 0.044 13.0 0.1 0.27 10.4 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF2267 PF10025.4 GAK66132.1 - 0.052 13.6 0.0 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) UCR_TM PF02921.9 GAK66133.1 - 4.5e-19 68.4 2.5 9.3e-19 67.4 1.7 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 GAK66133.1 - 2.5e-16 59.0 1.1 5.5e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Dynactin PF12455.3 GAK66134.1 - 6.9e-79 264.5 1.0 6.9e-79 264.5 0.7 2.6 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 GAK66134.1 - 5.5e-21 74.0 0.7 1.2e-20 72.9 0.5 1.6 1 0 0 1 1 1 1 CAP-Gly domain ATG16 PF08614.6 GAK66134.1 - 0.00081 19.2 17.3 0.00081 19.2 12.0 5.8 3 1 2 6 6 6 2 Autophagy protein 16 (ATG16) Lyase_catalyt PF09093.6 GAK66134.1 - 0.023 13.6 0.4 0.043 12.7 0.3 1.4 1 0 0 1 1 1 0 Lyase, catalytic Fcf1 PF04900.7 GAK66135.1 - 5e-25 87.5 0.6 5e-25 87.5 0.4 1.8 2 0 0 2 2 2 1 Fcf1 Tocopherol_cycl PF14249.1 GAK66137.1 - 0.00024 19.9 0.0 0.00047 18.9 0.0 1.4 1 0 0 1 1 1 1 Tocopherol cyclase Cellulase PF00150.13 GAK66138.1 - 4.8e-11 42.3 0.0 1e-05 24.9 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF974 PF06159.8 GAK66139.1 - 8e-67 225.3 0.0 1.2e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) IDO PF01231.13 GAK66140.1 - 4.3e-149 496.5 0.0 5.5e-149 496.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ACPS PF01648.15 GAK66140.1 - 1.9e-11 43.7 0.0 4.4e-10 39.3 0.0 2.9 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily Astro_capsid_p PF12226.3 GAK66140.1 - 0.085 12.0 0.8 0.24 10.6 0.4 1.8 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Peptidase_S49 PF01343.13 GAK66140.1 - 0.15 11.8 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Peptidase family S49 Ras PF00071.17 GAK66141.1 - 9.6e-66 220.1 1.1 1.1e-65 219.9 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK66141.1 - 6.9e-21 74.9 0.0 1.1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK66141.1 - 5.4e-18 64.8 0.2 7e-18 64.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAK66141.1 - 1.4e-06 27.6 0.1 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAK66141.1 - 1.6e-06 27.7 0.2 3.3e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAK66141.1 - 2.8e-05 24.0 0.1 5e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAK66141.1 - 4e-05 22.8 0.0 7e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 GAK66141.1 - 0.00079 19.5 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 GAK66141.1 - 0.0027 17.9 0.1 0.53 10.4 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 GAK66141.1 - 0.0048 16.1 0.1 0.043 13.0 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 GAK66141.1 - 0.0099 15.8 0.2 0.048 13.6 0.2 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAK66141.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 GAK66141.1 - 0.012 14.8 0.2 0.055 12.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAK66141.1 - 0.031 14.5 0.4 0.087 13.1 0.3 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 GAK66141.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 GAK66141.1 - 0.07 12.1 0.1 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 GAK66141.1 - 0.075 12.5 0.1 1.1 8.7 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Nse4_C PF08743.5 GAK66142.1 - 5.7e-21 74.3 0.0 1.3e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 GAK66142.1 - 2e-13 49.9 0.8 2e-13 49.9 0.6 2.2 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE SRR1 PF07985.7 GAK66143.1 - 2.5e-12 46.5 0.6 6e-08 32.4 0.1 2.3 2 0 0 2 2 2 2 SRR1 DUF2201_N PF13203.1 GAK66143.1 - 0.097 11.8 2.7 0.16 11.0 1.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain CAP-ZIP_m PF15255.1 GAK66143.1 - 1.6 8.6 10.4 3.4 7.5 7.2 1.5 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region Erf4 PF10256.4 GAK66144.1 - 5.1e-36 123.1 0.0 9.2e-36 122.2 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb5_C PF01191.14 GAK66144.1 - 2.3e-32 110.3 1.1 3.6e-32 109.7 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 GAK66144.1 - 3.4e-31 107.4 1.2 7.3e-31 106.4 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 GAK66144.1 - 0.00038 20.2 0.0 0.0013 18.4 0.0 2.0 2 0 0 2 2 2 1 Restriction endonuclease S6PP_C PF08472.5 GAK66144.1 - 0.046 13.3 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal KH_1 PF00013.24 GAK66145.1 - 4.8e-31 106.1 0.7 1.8e-09 37.1 0.0 6.0 6 0 0 6 6 6 5 KH domain KH_3 PF13014.1 GAK66145.1 - 2.6e-22 77.9 2.2 2.9e-07 29.9 0.1 6.0 7 0 0 7 7 7 4 KH domain ArsA_ATPase PF02374.10 GAK66146.1 - 3e-110 368.0 0.3 3.4e-110 367.8 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 GAK66146.1 - 6.9e-15 54.9 0.0 1.1e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAK66146.1 - 7.6e-08 32.4 0.0 3.1e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 GAK66146.1 - 1.9e-05 24.0 0.2 0.00011 21.5 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 GAK66146.1 - 4.4e-05 23.0 0.2 0.00048 19.6 0.1 2.4 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 GAK66146.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.5 1 1 0 1 1 1 1 YhjQ protein AAA_19 PF13245.1 GAK66146.1 - 0.0072 16.0 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 GAK66146.1 - 0.0076 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.1 GAK66146.1 - 0.0095 15.3 0.4 0.052 12.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 GAK66146.1 - 0.022 13.8 0.1 0.053 12.6 0.1 1.7 1 1 1 2 2 2 0 ATPase MipZ NB-ARC PF00931.17 GAK66146.1 - 0.031 13.1 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF972 PF06156.8 GAK66146.1 - 0.043 14.1 1.0 0.11 12.8 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AAA_24 PF13479.1 GAK66146.1 - 0.088 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAK66146.1 - 0.092 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein BPL_N PF09825.4 GAK66147.1 - 1.3e-79 267.6 0.0 1.6e-78 264.0 0.0 2.3 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal RTC PF01137.16 GAK66147.1 - 6.9e-57 191.8 0.0 1.1e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 GAK66147.1 - 1.9e-28 98.4 0.0 3.8e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain BPL_LplA_LipB PF03099.14 GAK66147.1 - 4.1e-12 46.2 0.0 9.3e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ribonuc_2-5A PF06479.7 GAK66148.1 - 3e-47 159.6 0.2 4.9e-47 158.9 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 GAK66148.1 - 2.9e-41 141.3 0.0 4.5e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66148.1 - 4.2e-19 68.6 0.0 1.1e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 GAK66148.1 - 9.8e-07 28.4 0.4 2.6e-05 23.8 0.1 2.8 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 GAK66148.1 - 1.4e-05 24.4 0.0 0.00054 19.3 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.1 GAK66148.1 - 0.016 15.5 0.3 6.1 7.2 0.0 4.1 3 1 0 3 3 3 0 PQQ-like domain Kdo PF06293.9 GAK66148.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_gE PF02480.11 GAK66148.1 - 0.037 12.2 0.3 0.1 10.8 0.1 1.9 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E YrbL-PhoP_reg PF10707.4 GAK66148.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4006 PF13179.1 GAK66148.1 - 0.095 12.2 0.9 0.21 11.1 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF2011 PF09428.5 GAK66148.1 - 4.9 7.0 11.2 0.14 12.0 3.2 1.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) TPR_19 PF14559.1 GAK66149.1 - 5.8e-08 32.9 0.3 2.5 8.5 0.5 6.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAK66149.1 - 2.4e-07 30.7 22.5 42 5.1 0.0 12.9 10 3 4 14 14 14 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAK66149.1 - 5.2e-07 29.5 11.0 3.8 7.5 0.1 7.9 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAK66149.1 - 2.3e-05 23.9 6.1 2.3 7.9 0.0 7.0 8 0 0 8 8 8 1 TPR repeat Mad3_BUB1_I PF08311.7 GAK66149.1 - 0.006 16.3 11.0 0.012 15.3 0.2 5.6 7 1 1 8 8 8 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 GAK66149.1 - 0.023 14.4 3.2 14 5.7 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAK66149.1 - 0.025 14.4 22.1 8.6 6.5 0.0 8.9 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAK66149.1 - 0.67 10.3 8.1 1.5e+02 2.9 0.2 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Zn_clus PF00172.13 GAK66150.1 - 3.6e-08 33.1 6.8 3.6e-08 33.1 4.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.13 GAK66151.1 - 6.3e-54 182.5 0.0 9.2e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain CybS PF05328.7 GAK66152.1 - 3.1e-45 153.0 0.0 4e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 CybS Ribosomal_L3 PF00297.17 GAK66153.1 - 1.2e-120 401.7 8.3 1.5e-120 401.5 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Oxidored_molyb PF00174.14 GAK66154.1 - 1.2e-52 177.6 0.0 2.7e-52 176.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAK66154.1 - 1.3e-43 147.7 0.1 2.3e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 GAK66154.1 - 1.2e-28 99.8 0.0 2.5e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 GAK66154.1 - 2.8e-22 78.3 0.1 5.8e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 GAK66154.1 - 1.2e-21 76.7 0.0 5.7e-21 74.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAK66154.1 - 0.015 15.2 0.0 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF1137 PF06587.6 GAK66154.1 - 0.095 12.3 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) NIR_SIR PF01077.17 GAK66155.1 - 3.7e-30 104.3 0.1 6.6e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 GAK66155.1 - 1.1e-23 84.2 0.0 3.6e-23 82.5 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 GAK66155.1 - 8.7e-15 54.5 3.8 5.9e-12 45.4 1.8 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.22 GAK66155.1 - 2e-12 47.3 1.7 4.2e-12 46.3 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.12 GAK66155.1 - 2.5e-12 46.2 0.0 5.5e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske_2 PF13806.1 GAK66155.1 - 5.9e-12 45.2 0.0 1.7e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 GAK66155.1 - 1.3e-09 37.4 0.2 4.1e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.1 GAK66155.1 - 3.2e-05 23.7 0.7 0.47 10.2 0.0 3.6 2 2 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAK66155.1 - 0.00012 22.1 2.0 0.015 15.4 0.1 3.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAK66155.1 - 0.053 12.3 2.5 0.24 10.1 0.2 2.7 1 1 1 2 2 2 0 FAD binding domain TrkA_N PF02254.13 GAK66155.1 - 0.12 12.3 1.0 3.8 7.5 0.1 2.9 3 0 0 3 3 3 0 TrkA-N domain MFS_1 PF07690.11 GAK66156.1 - 4.4e-28 98.0 28.4 4.4e-28 98.0 19.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Glu_synthase PF01645.12 GAK66158.1 - 3.3e-160 533.0 0.1 6.3e-160 532.0 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 GAK66158.1 - 5.5e-137 456.2 0.0 7.5e-137 455.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 GAK66158.1 - 3.6e-119 397.3 0.0 6.8e-119 396.3 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 GAK66158.1 - 5.3e-66 221.4 0.6 8.8e-66 220.7 0.4 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 GAK66158.1 - 3e-22 78.3 0.1 6.4e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 GAK66158.1 - 7.7e-15 55.2 0.0 2.4e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK66158.1 - 3.6e-11 43.4 0.1 5.7e-05 23.2 0.1 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK66158.1 - 2.9e-09 36.8 0.9 8.4e-09 35.3 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAK66158.1 - 5.1e-09 36.4 0.1 3.7e-05 24.0 0.0 3.3 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK66158.1 - 9e-07 27.6 2.1 6e-06 24.9 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 GAK66158.1 - 3e-06 26.3 0.8 0.012 14.5 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 GAK66158.1 - 7.8e-06 25.2 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 GAK66158.1 - 1.4e-05 24.1 3.9 0.00021 20.2 0.2 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 GAK66158.1 - 2.3e-05 23.5 2.7 0.00013 20.9 0.2 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAK66158.1 - 8.5e-05 21.7 5.6 0.0012 18.0 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 GAK66158.1 - 0.00054 19.5 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 GAK66158.1 - 0.00085 19.5 0.1 1 9.6 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FMN_dh PF01070.13 GAK66158.1 - 0.0016 17.3 1.0 0.0095 14.8 0.6 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase AdoHcyase_NAD PF00670.16 GAK66158.1 - 0.0019 18.0 1.9 0.67 9.7 0.2 3.4 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Thi4 PF01946.12 GAK66158.1 - 0.0038 16.3 1.2 0.016 14.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 GAK66158.1 - 0.008 15.2 0.4 0.02 13.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 GAK66158.1 - 0.028 14.1 0.1 0.06 13.0 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 GAK66158.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Shikimate_DH PF01488.15 GAK66158.1 - 0.051 13.6 0.2 18 5.4 0.1 2.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 GAK66158.1 - 0.057 11.6 0.2 1.2 7.2 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.7 GAK66158.1 - 0.08 11.8 0.5 0.96 8.2 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 GAK66158.1 - 0.11 12.1 0.2 0.3 10.7 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 GAK66158.1 - 0.13 11.6 1.1 0.72 9.2 0.1 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Rib_recp_KP_reg PF05104.7 GAK66159.1 - 1.7 9.1 4.8 2 8.8 3.4 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Adenylsucc_synt PF00709.16 GAK66160.1 - 9.2e-163 541.7 0.0 1e-162 541.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DNA_primase_lrg PF04104.9 GAK66161.1 - 1.1e-83 280.5 0.0 1.6e-83 279.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Nucleoporin_C PF03177.9 GAK66162.1 - 3.5e-101 339.5 5.3 3.5e-101 339.5 3.6 1.6 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 GAK66162.1 - 2.8e-38 131.7 0.0 3.9e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like BC10 PF06726.7 GAK66162.1 - 0.052 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 E1_dh PF00676.15 GAK66163.1 - 2.8e-112 374.2 0.3 3.3e-112 374.0 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAK66163.1 - 0.00089 18.2 0.1 0.0015 17.5 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 GAK66163.1 - 0.0025 17.3 4.9 0.0025 17.3 1.7 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NADH_B2 PF14813.1 GAK66164.1 - 0.00093 18.8 2.1 0.00093 18.8 1.4 1.3 1 1 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SWIRM PF04433.12 GAK66165.1 - 6.2e-35 119.1 0.1 1.4e-34 118.0 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 GAK66165.1 - 1.2e-10 40.7 4.0 2.1e-10 39.9 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 GAK66165.1 - 1.2e-07 31.6 0.0 3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAK66165.1 - 4.1e-07 29.9 0.0 4.4e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Macoilin PF09726.4 GAK66165.1 - 4.6 5.3 12.3 5.8 5.0 0.6 2.1 2 0 0 2 2 2 0 Transmembrane protein PhoD PF09423.5 GAK66166.1 - 1.4e-40 139.2 0.0 5e-40 137.4 0.1 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase His_biosynth PF00977.16 GAK66167.1 - 3.7e-41 140.8 0.5 2.1e-24 86.0 0.3 2.8 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.23 GAK66167.1 - 9.5e-23 80.6 0.0 2.1e-22 79.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 GAK66167.1 - 1.2e-07 31.4 0.1 6.1e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 GAK66167.1 - 4.2e-07 29.7 0.0 1.4e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 GAK66167.1 - 0.096 12.1 0.1 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase C26 Asp PF00026.18 GAK66169.1 - 1.5e-41 142.6 0.0 3e-41 141.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAK66169.1 - 1e-08 35.2 1.8 8.1e-08 32.3 0.5 2.6 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAK66169.1 - 4.8e-06 26.9 0.1 0.066 13.7 0.0 3.7 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 GAK66169.1 - 0.0002 20.9 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 GAK66169.1 - 0.0034 17.1 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ABC_membrane PF00664.18 GAK66170.1 - 2.9e-45 154.8 13.2 4e-22 78.9 1.5 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 GAK66170.1 - 1.2e-44 151.9 0.0 1.3e-25 90.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 GAK66170.1 - 1.7e-09 37.2 0.6 8.2e-05 21.9 0.0 4.0 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAK66170.1 - 4.6e-07 30.0 0.2 2.4 8.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 GAK66170.1 - 4.6e-06 26.1 0.2 0.019 14.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAK66170.1 - 1.4e-05 24.5 0.1 0.063 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 GAK66170.1 - 1.5e-05 25.1 0.9 0.97 9.5 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 GAK66170.1 - 2.3e-05 24.4 3.0 0.026 14.5 0.1 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 GAK66170.1 - 0.00017 21.9 0.0 0.91 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 GAK66170.1 - 0.00031 19.7 0.0 0.14 11.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 GAK66170.1 - 0.0015 18.0 0.0 1.9 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 GAK66170.1 - 0.0045 16.6 0.3 0.45 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 GAK66170.1 - 0.0046 16.6 0.7 4.1 7.0 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 GAK66170.1 - 0.0057 16.5 0.4 4.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 GAK66170.1 - 0.006 16.1 0.1 3 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 GAK66170.1 - 0.011 16.2 0.1 5.5 7.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 GAK66170.1 - 0.011 15.1 2.2 0.044 13.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 GAK66170.1 - 0.017 14.8 2.8 0.34 10.6 0.1 3.7 3 0 0 3 3 2 0 Part of AAA domain MMR_HSR1 PF01926.18 GAK66170.1 - 0.018 14.9 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 GAK66170.1 - 0.027 15.2 4.9 2.5 8.9 1.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAK66170.1 - 0.034 13.5 0.0 11 5.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 GAK66170.1 - 0.036 13.9 0.1 3.9 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAK66170.1 - 0.045 12.9 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 GAK66170.1 - 0.081 12.7 0.2 0.27 11.0 0.0 2.0 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_14 PF13173.1 GAK66170.1 - 0.13 12.1 0.2 15 5.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 GAK66170.1 - 0.15 11.4 0.0 56 3.1 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 GAK66170.1 - 0.19 11.2 2.6 2.2 7.7 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 GAK66170.1 - 0.22 10.3 0.1 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 GAK66170.1 - 0.26 10.9 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 GAK66170.1 - 0.31 11.3 5.0 11 6.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 GAK66170.1 - 0.36 10.0 0.1 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.10 GAK66170.1 - 0.44 10.2 2.4 15 5.2 0.0 2.7 3 0 0 3 3 2 0 NTPase ATP11 PF06644.6 GAK66171.1 - 5.3e-81 272.0 2.8 8e-81 271.4 2.0 1.3 1 0 0 1 1 1 1 ATP11 protein Nefa_Nip30_N PF10187.4 GAK66171.1 - 3.5 7.8 8.4 1.4 9.1 1.1 2.7 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 U3_assoc_6 PF08640.6 GAK66172.1 - 9.5e-23 79.7 0.3 5.4e-22 77.3 0.1 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 GAK66172.1 - 0.0019 18.6 5.9 3.4 8.5 0.0 5.5 3 1 1 4 4 4 2 Tetratricopeptide repeat IFT20 PF14931.1 GAK66172.1 - 0.066 13.1 0.4 0.24 11.3 0.3 1.9 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Ras PF00071.17 GAK66173.1 - 7.1e-66 220.5 0.0 8.6e-66 220.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK66173.1 - 3e-19 69.6 0.0 4.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK66173.1 - 4.7e-14 52.0 0.0 5.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAK66173.1 - 1e-06 28.0 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAK66173.1 - 1.2e-05 24.8 0.1 3e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAK66173.1 - 4.4e-05 23.4 0.0 0.00014 21.8 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK66173.1 - 0.00031 20.0 0.0 0.0038 16.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 GAK66173.1 - 0.00051 19.3 0.0 0.00066 18.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 GAK66173.1 - 0.027 14.4 0.2 0.05 13.5 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 GAK66173.1 - 0.036 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 GAK66173.1 - 0.043 13.0 0.0 0.071 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAK66173.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 GAK66173.1 - 0.048 13.8 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAK66173.1 - 0.068 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Tox-PLDMTX PF15645.1 GAK66173.1 - 0.076 13.0 0.1 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold Septin PF00735.13 GAK66173.1 - 0.094 11.7 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_5 PF07728.9 GAK66173.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RhoGAP PF00620.22 GAK66174.1 - 8.5e-47 158.5 0.7 7.8e-46 155.4 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 GAK66174.1 - 3.6e-15 55.7 30.3 5.3e-09 36.0 5.4 3.4 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 GAK66174.1 - 5.7e-07 29.1 7.7 5.7e-07 29.1 5.3 4.1 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Rotamase_2 PF13145.1 GAK66174.1 - 2 9.0 13.4 1.3 9.6 1.2 3.5 3 0 0 3 3 3 0 PPIC-type PPIASE domain Filament PF00038.16 GAK66174.1 - 4.6 6.6 32.1 0.48 9.8 5.7 2.9 2 1 1 3 3 3 0 Intermediate filament protein RNA_pol_Rpb1_1 PF04997.7 GAK66175.1 - 5.2e-111 371.1 0.0 7.2e-111 370.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 GAK66175.1 - 2.8e-103 344.9 0.1 4.1e-103 344.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAK66175.1 - 2.3e-66 222.8 0.0 4.5e-66 221.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 GAK66175.1 - 3.9e-61 206.0 0.1 1.3e-60 204.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 GAK66175.1 - 1.7e-46 157.3 1.3 1.7e-46 157.3 0.9 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 GAK66175.1 - 1.9e-45 154.4 0.0 3.4e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 GAK66175.1 - 1.8e-36 124.1 0.0 4e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 GAK66175.1 - 5.2e-17 60.3 179.4 0.012 15.7 6.4 13.7 10 1 5 15 15 15 14 RNA polymerase Rpb1 C-terminal repeat VHS PF00790.14 GAK66176.1 - 1.9e-38 131.2 4.4 2.9e-38 130.6 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 GAK66176.1 - 5.3e-17 61.4 10.7 1.1e-16 60.4 7.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 GAK66176.1 - 1e-05 24.6 5.4 0.0071 15.8 0.3 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 GAK66176.1 - 0.0046 16.8 4.5 0.0089 15.9 3.1 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger ENTH PF01417.15 GAK66176.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ENTH domain zf-RING_5 PF14634.1 GAK66176.1 - 2.8 7.7 10.3 5.5 6.8 7.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain NmrA PF05368.8 GAK66177.1 - 2.9e-46 157.6 0.1 3.5e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAK66177.1 - 1.7e-14 54.2 0.0 2.8e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAK66177.1 - 1.6e-05 23.7 0.0 2.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAK66177.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.1 GAK66178.1 - 1.5e-15 58.2 0.0 4.8e-15 56.5 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAK66178.1 - 1.8e-15 56.6 0.1 4.9e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3176 PF11374.3 GAK66179.1 - 8.9e-05 22.3 0.5 0.00014 21.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) ESSS PF10183.4 GAK66179.1 - 0.13 12.6 0.1 0.13 12.6 0.1 1.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ABC_tran PF00005.22 GAK66180.1 - 2.5e-43 147.6 0.0 9.7e-22 77.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 GAK66180.1 - 8.7e-30 104.0 39.9 6.1e-22 78.3 7.1 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAK66180.1 - 6.8e-10 38.5 2.1 0.0064 15.7 0.2 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAK66180.1 - 9.4e-10 38.7 6.0 0.00022 21.2 2.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 GAK66180.1 - 1.4e-09 38.3 0.1 0.17 11.8 0.0 4.3 3 1 1 4 4 4 2 AAA domain DUF258 PF03193.11 GAK66180.1 - 1.2e-08 34.3 0.4 0.0035 16.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAK66180.1 - 3.6e-07 29.6 1.3 0.011 15.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAK66180.1 - 3.7e-06 26.4 0.3 0.015 14.6 0.1 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 GAK66180.1 - 3.4e-05 22.8 0.8 0.081 11.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 GAK66180.1 - 4.3e-05 23.4 0.0 0.019 14.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 GAK66180.1 - 7.6e-05 23.1 0.5 0.27 11.5 0.2 2.2 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 GAK66180.1 - 9.5e-05 21.9 0.1 0.35 10.3 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 GAK66180.1 - 0.0001 22.8 0.0 0.12 12.8 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 GAK66180.1 - 0.00013 22.1 0.1 1 9.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 GAK66180.1 - 0.00043 19.2 0.1 0.85 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Dynamin_N PF00350.18 GAK66180.1 - 0.0012 18.6 0.8 0.065 13.0 0.1 2.3 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 GAK66180.1 - 0.0016 18.2 3.5 0.22 11.4 0.1 3.7 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 GAK66180.1 - 0.0077 15.7 0.7 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 GAK66180.1 - 0.015 16.0 0.2 1.5 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAK66180.1 - 0.017 14.8 0.1 0.27 10.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 GAK66180.1 - 0.028 13.0 0.2 1.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 GAK66180.1 - 0.032 13.8 0.8 14 5.2 0.0 3.5 3 0 0 3 3 3 0 NACHT domain Viral_helicase1 PF01443.13 GAK66180.1 - 0.099 12.1 0.1 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 GAK66180.1 - 0.11 12.3 2.9 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 GAK66180.1 - 0.11 12.1 0.5 32 4.2 0.1 3.1 2 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAK66180.1 - 0.14 12.5 0.1 19 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAK66180.1 - 0.23 11.1 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 GAK66180.1 - 0.29 10.1 0.4 8.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin UPF0137 PF03677.8 GAK66180.1 - 0.32 10.4 0.0 0.66 9.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) IIGP PF05049.8 GAK66180.1 - 0.34 9.6 0.3 1.2 7.8 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AMP-binding PF00501.23 GAK66181.1 - 5.2e-47 160.1 0.0 8.7e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme 2-Hacid_dh_C PF02826.14 GAK66181.1 - 1.5e-37 128.4 0.0 3.1e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.16 GAK66181.1 - 2e-35 122.4 0.0 3.3e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II 2-Hacid_dh PF00389.25 GAK66181.1 - 1.8e-09 37.1 0.0 3.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Glyoxalase_4 PF13669.1 GAK66181.1 - 3.7e-06 26.8 0.1 1.8e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily XdhC_C PF13478.1 GAK66181.1 - 0.0073 16.6 0.1 0.079 13.2 0.0 2.8 3 0 0 3 3 3 1 XdhC Rossmann domain NAD_binding_2 PF03446.10 GAK66181.1 - 0.016 15.0 0.0 0.33 10.7 0.0 2.5 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 GAK66181.1 - 0.15 11.8 0.1 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 ThiF family Zn_clus PF00172.13 GAK66182.1 - 0.00059 19.6 8.0 0.0012 18.7 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF508 PF04370.7 GAK66182.1 - 0.32 10.6 1.8 3.1 7.3 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF508) Peroxidase_2 PF01328.12 GAK66184.1 - 2.3e-13 49.5 2.4 2.1e-12 46.3 1.7 2.2 1 1 0 1 1 1 1 Peroxidase, family 2 Pro_isomerase PF00160.16 GAK66185.1 - 1e-49 168.6 0.0 2.6e-49 167.4 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 GAK66185.1 - 6.8e-05 22.6 5.7 0.0014 18.3 0.3 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Mito_carr PF00153.22 GAK66186.1 - 1.7e-46 155.8 10.1 2.3e-15 56.0 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein CH PF00307.26 GAK66187.1 - 1.4e-40 137.6 0.0 1e-21 76.9 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 GAK66187.1 - 1.9e-20 72.6 0.0 4.9e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 GAK66187.1 - 2.3e-13 49.6 0.2 1.6e-09 37.2 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain Spectrin PF00435.16 GAK66187.1 - 2.6e-07 30.8 2.0 0.021 15.1 0.0 3.0 2 0 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.1 GAK66187.1 - 0.00012 21.6 0.0 0.00075 19.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 GAK66187.1 - 0.0035 16.5 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 EF hand Baculo_PEP_C PF04513.7 GAK66187.1 - 0.027 14.3 0.5 0.18 11.6 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AlkA_N PF06029.6 GAK66187.1 - 0.041 13.9 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AlkA N-terminal domain EF-hand_5 PF13202.1 GAK66187.1 - 0.082 12.2 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 EF hand Cofilin_ADF PF00241.15 GAK66189.1 - 7.1e-44 148.7 1.2 8.6e-44 148.4 0.8 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HLH PF00010.21 GAK66191.1 - 6.7e-15 54.5 0.3 1.2e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Prenylcys_lyase PF07156.9 GAK66192.1 - 3.9e-35 121.4 0.0 6.5e-17 61.4 0.0 2.5 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 GAK66192.1 - 2.2e-10 40.4 0.0 8.3e-10 38.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAK66192.1 - 1.1e-07 31.3 0.4 3.7e-06 26.2 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 GAK66192.1 - 0.00018 21.2 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAK66192.1 - 0.00052 20.1 0.1 0.003 17.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK66192.1 - 0.00059 18.8 0.3 0.0037 16.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAK66192.1 - 0.013 15.3 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK66192.1 - 0.031 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Na_H_Exchanger PF00999.16 GAK66193.1 - 2.1e-59 200.9 40.8 3.1e-59 200.4 28.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PP2C PF00481.16 GAK66194.1 - 2.5e-79 266.2 0.0 3.7e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.27 GAK66195.1 - 9.5e-30 101.3 0.0 2.3e-08 33.6 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Gmad1 PF10647.4 GAK66195.1 - 2.5e-05 23.7 0.2 4.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 GAK66195.1 - 0.00037 18.7 0.2 0.0038 15.4 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF1073 PF06381.6 GAK66195.1 - 0.051 12.0 0.0 0.069 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Nucleoporin_N PF08801.6 GAK66195.1 - 0.15 10.7 0.6 1.3 7.7 0.0 2.6 1 1 0 2 2 2 0 Nup133 N terminal like PH_5 PF15405.1 GAK66196.1 - 2.7 7.9 4.7 0.71 9.8 0.5 2.0 1 1 1 2 2 2 0 Pleckstrin homology domain PH_10 PF15411.1 GAK66197.1 - 2.3e-30 105.1 0.0 4.1e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 GAK66197.1 - 3.7e-06 26.6 1.0 8.2e-06 25.5 0.7 1.6 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 GAK66197.1 - 0.0017 18.0 0.0 0.74 9.5 0.0 2.9 2 0 0 2 2 2 2 von Willebrand factor type A domain zf-RING_5 PF14634.1 GAK66197.1 - 0.0031 17.1 1.3 0.014 15.1 1.2 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAK66197.1 - 0.0079 16.1 0.6 0.017 15.1 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK66197.1 - 0.018 14.6 0.2 0.038 13.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 GAK66197.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain zf-C3HC4_3 PF13920.1 GAK66197.1 - 0.075 12.7 1.1 0.21 11.2 0.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAK66197.1 - 0.079 13.0 0.2 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger Ribonuc_red_lgC PF02867.10 GAK66198.1 - 2.3e-216 719.5 0.0 3e-216 719.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 GAK66198.1 - 3.9e-25 87.4 0.0 1.2e-24 85.9 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 GAK66198.1 - 1.2e-16 60.8 0.3 1.2e-16 60.8 0.2 2.8 3 0 0 3 3 3 1 ATP cone domain NRDD PF13597.1 GAK66198.1 - 0.0067 14.5 0.0 0.01 13.9 0.0 1.3 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Na_Ca_ex PF01699.19 GAK66201.1 - 7.7e-28 96.8 24.7 4.6e-15 55.4 6.6 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF307 PF03733.8 GAK66201.1 - 2e-13 50.5 7.5 2e-13 50.5 5.2 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF307) DUF1556 PF07590.6 GAK66202.1 - 0.17 12.1 2.3 0.21 11.8 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1556) Ufd2P_core PF10408.4 GAK66203.1 - 1.8e-183 611.2 0.0 2.1e-183 610.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 GAK66203.1 - 2.4e-28 97.8 0.2 7.7e-28 96.2 0.1 2.0 1 0 0 1 1 1 1 U-box domain BCNT PF07572.7 GAK66204.1 - 8e-19 67.3 2.1 2.1e-18 66.0 1.4 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development COX4 PF02936.9 GAK66204.1 - 0.012 15.3 0.3 0.47 10.1 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Macoilin PF09726.4 GAK66205.1 - 5.5 5.1 5.6 6.3 4.9 3.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4505 PF14956.1 GAK66206.1 - 8.2e-27 94.0 0.0 1.4e-13 50.8 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4505) Yos1 PF08571.5 GAK66207.1 - 3e-28 97.7 0.9 5.1e-28 96.9 0.6 1.4 1 0 0 1 1 1 1 Yos1-like Ribosomal_S8 PF00410.14 GAK66207.1 - 5.7e-15 55.3 0.0 9e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 MDMPI_C PF07398.6 GAK66207.1 - 0.072 13.6 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 MDMPI C-terminal domain DnaJ PF00226.26 GAK66208.1 - 3.3e-26 90.7 1.9 4.7e-26 90.3 1.3 1.2 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAK66208.1 - 7.2e-14 51.4 1.0 3e-11 43.0 0.0 2.9 2 2 0 2 2 2 2 DnaJ C terminal domain UDG PF03167.14 GAK66210.1 - 1.9e-15 56.6 0.0 3.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Arrestin_N PF00339.24 GAK66211.1 - 0.0013 18.5 0.0 0.0034 17.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 GAK66211.1 - 0.034 13.6 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 Arrestin_N terminal like Aldedh PF00171.17 GAK66212.1 - 1.6e-156 521.2 0.1 1.9e-156 520.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAK66212.1 - 0.027 13.6 0.0 0.094 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ldh_2 PF02615.9 GAK66212.1 - 0.031 12.9 0.1 0.053 12.2 0.1 1.3 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase NDUFA12 PF05071.11 GAK66213.1 - 1.5e-25 89.6 1.6 1.9e-25 89.3 1.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 MIS13 PF08202.6 GAK66214.1 - 1.3e-18 67.1 9.9 1.3e-18 67.1 6.9 3.6 2 1 0 2 2 2 1 Mis12-Mtw1 protein family GAGE PF05831.6 GAK66217.1 - 0.0011 19.0 2.6 0.0034 17.4 1.8 1.9 1 0 0 1 1 1 1 GAGE protein Flavokinase PF01687.12 GAK66218.1 - 1.6e-35 121.7 0.0 3.5e-35 120.6 0.0 1.5 1 1 0 1 1 1 1 Riboflavin kinase DUF3678 PF12435.3 GAK66218.1 - 0.9 9.1 8.8 0.59 9.7 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Thr_synth_N PF14821.1 GAK66221.1 - 2.6e-26 91.4 0.0 6e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 GAK66221.1 - 4.2e-17 62.3 0.0 8.1e-16 58.1 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pox_A_type_inc PF04508.7 GAK66222.1 - 0.11 12.3 4.4 0.35 10.7 3.0 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CAP PF00188.21 GAK66223.1 - 2.9e-13 50.3 2.6 2.9e-13 50.3 1.8 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Mitofilin PF09731.4 GAK66223.1 - 0.46 9.0 6.0 0.58 8.7 4.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein XPG_I PF00867.13 GAK66224.1 - 1.9e-11 43.8 0.2 8.8e-11 41.7 0.0 2.3 2 1 0 2 2 2 1 XPG I-region XPG_N PF00752.12 GAK66224.1 - 3e-06 27.3 0.0 5.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 GAK66224.1 - 1.6e-05 25.0 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Remorin_C PF03763.8 GAK66224.1 - 0.014 14.9 1.5 0.027 13.9 1.0 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region HHH_5 PF14520.1 GAK66224.1 - 0.052 13.7 1.0 0.15 12.2 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH PF00633.18 GAK66224.1 - 0.058 13.1 0.1 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3135 PF11333.3 GAK66224.1 - 0.13 12.4 3.4 1.8 8.7 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) V-ATPase_G PF03179.10 GAK66225.1 - 3e-34 117.4 15.0 4.2e-34 117.0 10.4 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 GAK66225.1 - 0.0057 16.4 19.2 0.017 14.9 9.6 2.1 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) PAXIP1_C PF15364.1 GAK66225.1 - 0.031 14.1 6.3 0.05 13.5 4.4 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Seryl_tRNA_N PF02403.17 GAK66225.1 - 0.039 13.9 12.0 0.067 13.2 7.7 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rotamase_2 PF13145.1 GAK66225.1 - 0.41 11.2 7.2 0.7 10.5 5.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Prismane PF03063.15 GAK66225.1 - 0.58 8.4 3.3 0.72 8.1 2.3 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family ATP-synt_F6 PF05511.6 GAK66225.1 - 0.6 10.0 5.1 2 8.3 2.8 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Symplekin_C PF12295.3 GAK66226.1 - 2.2e-60 203.6 0.1 8.3e-60 201.8 0.0 2.1 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 GAK66226.1 - 1.1e-59 201.7 2.7 2.3e-59 200.7 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Exonuc_VIII PF06630.6 GAK66226.1 - 0.064 12.5 0.1 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII OPT PF03169.10 GAK66227.1 - 7.6e-172 572.9 55.4 8.7e-172 572.7 38.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_3 PF01494.14 GAK66229.1 - 3.6e-88 296.0 0.0 5.5e-88 295.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAK66229.1 - 4.6e-52 176.0 0.0 1e-51 174.8 0.0 1.6 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 GAK66229.1 - 4.7e-05 22.0 0.8 7.5e-05 21.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 GAK66229.1 - 0.00016 20.7 0.3 0.00046 19.2 0.2 1.8 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAK66229.1 - 0.00038 19.4 0.3 0.0023 16.8 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 GAK66229.1 - 0.00049 19.0 0.4 0.0061 15.5 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAK66229.1 - 0.0007 19.5 1.9 0.0011 18.9 0.1 2.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK66229.1 - 0.00081 19.3 0.1 0.0022 17.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAK66229.1 - 0.0019 17.3 0.1 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 GAK66229.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 GAK66229.1 - 0.028 13.0 0.1 0.05 12.2 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 GAK66229.1 - 0.034 14.5 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK66229.1 - 0.074 12.8 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 GAK66229.1 - 0.089 11.6 0.2 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 GAK66229.1 - 0.23 10.2 0.0 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase His_Phos_2 PF00328.17 GAK66230.1 - 1.1e-39 136.7 0.0 1.4e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sec7 PF01369.15 GAK66231.1 - 4.7e-63 212.2 0.0 1.2e-62 210.9 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 GAK66231.1 - 1e-56 190.9 4.8 1e-56 190.9 3.3 3.4 5 1 1 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAK66231.1 - 1.5e-31 107.7 6.1 8.7e-31 105.3 0.1 4.8 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Mob1_phocein PF03637.12 GAK66232.1 - 2.1e-73 245.6 0.2 2.5e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family E1-E2_ATPase PF00122.15 GAK66233.1 - 1.6e-51 174.5 5.6 1.6e-51 174.5 3.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAK66233.1 - 1.8e-23 84.0 0.3 8.7e-23 81.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 GAK66233.1 - 1.3e-16 60.7 8.5 1.3e-16 60.7 5.9 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 GAK66233.1 - 2.5e-15 55.6 0.0 5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAK66233.1 - 6.2e-15 55.8 0.4 3.6e-14 53.3 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK66233.1 - 2e-07 30.8 0.0 4.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAK66233.1 - 0.0011 18.5 0.0 0.0033 17.0 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF443 PF04276.7 GAK66233.1 - 0.04 13.3 3.9 2.2 7.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) NAD4L PF06235.6 GAK66233.1 - 0.72 9.6 8.3 0.03 14.0 1.4 1.9 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) Glyco_tranf_2_3 PF13641.1 GAK66234.1 - 1.1e-29 103.8 0.0 1.5e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAK66234.1 - 2.2e-17 63.3 5.8 2.2e-17 63.3 4.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 GAK66234.1 - 7.1e-08 31.9 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAK66234.1 - 1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF982 PF06169.7 GAK66234.1 - 0.019 14.7 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF982) PIG-P PF08510.7 GAK66234.1 - 0.1 12.2 3.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 PIG-P Acyl_transf_3 PF01757.17 GAK66235.1 - 1.8e-14 53.3 37.1 3.3e-14 52.4 25.7 1.4 1 0 0 1 1 1 1 Acyltransferase family Glyco_hydro_16 PF00722.16 GAK66235.1 - 1.5e-06 27.6 0.1 2.5e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sel1 PF08238.7 GAK66236.1 - 6.5e-25 86.9 41.0 9.2e-05 22.9 0.2 10.4 11 1 0 11 11 11 7 Sel1 repeat Med5 PF08689.5 GAK66236.1 - 0.36 8.4 0.0 0.54 7.8 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 TPR_8 PF13181.1 GAK66236.1 - 4.1 7.3 0.0 4.1 7.3 0.0 4.2 7 0 0 7 7 7 0 Tetratricopeptide repeat DRIM PF07539.7 GAK66237.1 - 5.7e-43 145.7 0.0 1.9e-42 144.0 0.0 2.0 1 0 0 1 1 1 1 Down-regulated in metastasis Glyco_hydro_30 PF02055.11 GAK66238.1 - 4.4e-21 74.6 0.1 7.6e-21 73.8 0.1 1.4 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 7TM-7TMR_HD PF07698.6 GAK66238.1 - 0.024 14.0 0.3 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase RskA PF10099.4 GAK66238.1 - 0.037 13.7 1.9 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA AMP-binding PF00501.23 GAK66240.1 - 9.1e-85 284.5 0.0 1.3e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK66240.1 - 1e-09 39.1 0.2 3.2e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Kri1 PF05178.7 GAK66242.1 - 6.3e-30 103.4 9.8 6.3e-30 103.4 6.8 4.0 4 0 0 4 4 4 1 KRI1-like family Kri1_C PF12936.2 GAK66242.1 - 2e-26 91.7 0.1 2e-26 91.7 0.1 3.0 3 0 0 3 3 3 1 KRI1-like family C-terminal DnaJ_CXXCXGXG PF00684.14 GAK66242.1 - 0.17 11.9 23.0 0.067 13.2 10.2 2.5 2 0 0 2 2 2 0 DnaJ central domain p450 PF00067.17 GAK66243.1 - 1.3e-20 73.4 0.1 5.1e-20 71.4 0.0 2.0 2 1 0 2 2 2 1 Cytochrome P450 GTP1_OBG PF01018.17 GAK66244.1 - 3.5e-39 133.9 2.3 6.8e-28 97.2 1.1 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 GAK66244.1 - 2.2e-17 63.0 0.0 5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.17 GAK66244.1 - 6.5e-06 25.6 0.0 1.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FeoB_N PF02421.13 GAK66244.1 - 0.00013 21.3 0.1 0.00036 19.8 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RRM_6 PF14259.1 GAK66244.1 - 0.00037 20.4 0.0 0.00086 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 GAK66244.1 - 0.0022 17.4 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 GAK66244.1 - 0.02 13.6 0.2 0.98 8.1 0.0 2.3 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 GAK66244.1 - 0.09 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RRM_5 PF13893.1 GAK66244.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cobW PF02492.14 GAK66244.1 - 0.096 12.1 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 GAK66244.1 - 0.098 11.7 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 GAK66244.1 - 0.11 12.2 0.0 8.3 6.2 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Arf PF00025.16 GAK66244.1 - 0.15 11.2 0.0 0.57 9.3 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Ashwin PF15323.1 GAK66244.1 - 1 9.2 7.0 0.17 11.8 0.8 2.5 3 0 0 3 3 3 0 Developmental protein Cellulase PF00150.13 GAK66245.1 - 1.5e-10 40.8 0.2 1.5e-10 40.8 0.1 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RCC1 PF00415.13 GAK66247.1 - 3.4e-40 136.0 5.8 1.9e-09 37.5 0.1 6.6 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAK66247.1 - 2.4e-22 77.9 23.3 2.5e-07 30.1 0.8 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 GAK66247.1 - 3.8e-10 39.3 7.5 8.5e-10 38.1 5.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-UDP PF14569.1 GAK66247.1 - 0.013 15.2 2.4 0.023 14.4 1.0 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING-like PF08746.6 GAK66247.1 - 0.078 12.9 4.0 0.22 11.5 2.8 1.8 1 0 0 1 1 1 0 RING-like domain PHD_2 PF13831.1 GAK66247.1 - 0.35 10.2 6.9 0.092 12.0 2.6 1.8 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 GAK66247.1 - 9.1 6.0 10.8 0.05 13.3 0.6 2.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 Glyco_trans_2_3 PF13632.1 GAK66248.1 - 4.3e-10 39.6 1.6 8.8e-10 38.6 1.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK66248.1 - 3.3e-09 36.8 0.0 7.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAK66248.1 - 1.8e-05 24.4 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAK66248.1 - 0.0012 18.1 0.1 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 PAN_4 PF14295.1 GAK66250.1 - 0.051 13.2 2.1 2.4 7.9 0.1 2.9 2 0 0 2 2 2 0 PAN domain Transp_cyt_pur PF02133.10 GAK66251.1 - 7.9e-91 304.8 33.7 9.2e-91 304.5 23.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_M28 PF04389.12 GAK66252.1 - 1.3e-28 99.9 0.0 2.1e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PrmA PF06325.8 GAK66253.1 - 2.8e-12 46.3 0.0 4.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 GAK66253.1 - 5.8e-12 45.4 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK66253.1 - 5.9e-11 42.9 0.2 3.4e-10 40.4 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK66253.1 - 5e-09 36.2 0.2 1.8e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAK66253.1 - 4e-08 32.8 0.0 7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 GAK66253.1 - 1e-07 31.2 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 GAK66253.1 - 1.2e-06 28.3 0.0 1.2e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK66253.1 - 3.4e-06 27.3 0.0 1.3e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK66253.1 - 4.1e-06 27.1 0.0 1.4e-05 25.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 GAK66253.1 - 8.1e-06 25.1 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 GAK66253.1 - 3.6e-05 23.2 0.0 5.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 GAK66253.1 - 6.9e-05 23.2 0.1 0.00047 20.5 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain PCMT PF01135.14 GAK66253.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 GAK66253.1 - 0.0018 19.0 3.4 0.0051 17.6 0.0 3.2 3 2 1 4 4 4 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAK66253.1 - 0.003 16.3 0.0 0.0079 14.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.10 GAK66253.1 - 0.003 16.9 0.1 0.0074 15.6 0.0 1.6 2 0 0 2 2 1 1 Conserved hypothetical protein 95 FtsJ PF01728.14 GAK66253.1 - 0.0058 16.6 0.1 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase UPF0020 PF01170.13 GAK66253.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 HIRA_B PF09453.5 GAK66253.1 - 0.023 14.2 0.1 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 HIRA B motif Methyltransf_32 PF13679.1 GAK66253.1 - 0.041 13.5 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pox_A_type_inc PF04508.7 GAK66253.1 - 0.33 10.8 4.5 0.51 10.2 0.5 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SQS_PSY PF00494.14 GAK66254.1 - 1.7e-34 119.3 0.0 2.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase SelB-wing_2 PF09106.6 GAK66254.1 - 0.046 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Prenyltrans PF00432.16 GAK66255.1 - 4.5e-34 115.6 11.7 3.5e-12 45.6 0.1 6.8 5 2 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAK66255.1 - 5.3e-25 88.0 0.1 4.8e-14 52.7 0.0 4.7 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAK66255.1 - 3.9e-12 46.1 0.0 1.8e-06 27.8 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 GAK66255.1 - 0.0014 17.9 0.0 0.64 9.2 0.0 3.4 2 2 2 4 4 4 1 A-macroglobulin complement component Dynein_heavy PF03028.10 GAK66257.1 - 7.2e-160 533.3 0.0 1.6e-159 532.2 0.0 1.5 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 GAK66257.1 - 1.2e-47 162.3 5.3 3.1e-47 160.9 3.6 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 GAK66257.1 - 2.2e-44 151.0 0.0 4.6e-44 149.9 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 Sipho_Gp157 PF05565.6 GAK66257.1 - 0.006 16.1 1.4 0.006 16.1 1.0 3.7 3 0 0 3 3 3 2 Siphovirus Gp157 DUF4250 PF14056.1 GAK66257.1 - 0.054 13.2 0.6 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Mod_r PF07200.8 GAK66257.1 - 0.22 11.4 16.0 0.4 10.5 0.5 3.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 GAK66257.1 - 9.4 5.1 29.6 0.13 11.2 1.6 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 eIF2A PF08662.6 GAK66258.1 - 9.8e-83 276.6 0.2 4.9e-81 271.0 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 GAK66258.1 - 0.15 11.9 3.6 4.2 7.3 0.0 4.5 5 1 0 5 5 5 0 WD domain, G-beta repeat CDV3 PF15359.1 GAK66258.1 - 0.27 11.3 8.8 0.04 13.9 1.2 2.9 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 TauD PF02668.11 GAK66259.1 - 4.4e-30 105.2 0.2 5.6e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidohydro_2 PF04909.9 GAK66260.1 - 1.1e-30 107.1 1.7 1.9e-30 106.3 1.2 1.4 1 1 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 GAK66261.1 - 1.7e-124 415.6 0.0 6.7e-124 413.7 0.0 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK66261.1 - 0.0025 16.6 0.0 0.0039 15.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DIOX_N PF14226.1 GAK66262.1 - 3.1e-24 85.7 0.1 4.9e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAK66262.1 - 1.7e-19 69.9 0.0 7.5e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily APG9 PF04109.11 GAK66263.1 - 7.8e-161 535.0 0.1 9.7e-161 534.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF2231 PF09990.4 GAK66263.1 - 0.0019 18.5 1.4 0.0019 18.5 1.0 2.8 2 1 1 3 3 3 1 Predicted membrane protein (DUF2231) SNF5 PF04855.7 GAK66264.1 - 8.7e-82 274.2 0.0 8.7e-82 274.2 0.0 3.7 3 1 0 3 3 3 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 GAK66264.1 - 0.0003 20.0 1.7 0.00058 19.1 1.1 1.5 1 0 0 1 1 1 1 GATA zinc finger CPSase_L_D2 PF02786.12 GAK66265.1 - 2.6e-75 252.3 0.0 5.1e-75 251.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAK66265.1 - 1.1e-41 141.3 0.1 3e-41 139.9 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAK66265.1 - 4.2e-34 116.7 0.0 4.1e-33 113.5 0.0 2.4 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 GAK66265.1 - 1.1e-15 57.8 0.1 3.1e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAK66265.1 - 4.7e-13 48.5 0.0 8.2e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 GAK66265.1 - 2.7e-11 42.9 0.2 6.3e-11 41.7 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 GAK66265.1 - 2.9e-10 39.8 0.0 6.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAK66265.1 - 3.4e-07 29.7 0.0 1.8e-06 27.3 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAK66265.1 - 4.5e-07 29.4 0.0 1.4e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 GAK66265.1 - 6.2e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 GAK66265.1 - 0.00081 19.0 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 GAK66265.1 - 0.0026 17.2 0.0 0.018 14.5 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain EMP24_GP25L PF01105.19 GAK66266.1 - 1.9e-43 148.2 0.0 2.2e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1903 PF08991.5 GAK66267.1 - 9e-06 25.7 2.7 1.3e-05 25.2 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 GAK66267.1 - 3.5e-05 23.5 4.8 4.9e-05 23.1 3.4 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.8 GAK66267.1 - 9.8e-05 21.7 2.6 0.00014 21.2 1.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.12 GAK66267.1 - 0.0019 18.1 3.5 0.0028 17.6 2.5 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 GAK66267.1 - 0.031 14.2 2.4 0.046 13.7 1.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 GAK66267.1 - 0.035 13.9 2.0 0.042 13.7 0.4 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) NuA4 PF09340.5 GAK66268.1 - 2.7e-22 78.1 0.1 5.9e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 GKAP PF03359.8 GAK66270.1 - 4.2 6.8 9.0 6.3 6.3 6.2 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein ER_lumen_recept PF00810.13 GAK66271.1 - 5.3e-58 195.6 7.6 7.4e-58 195.2 5.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 GAK66271.1 - 0.0001 21.7 4.2 0.64 9.6 0.0 4.0 3 1 1 4 4 4 2 PQ loop repeat DUF485 PF04341.7 GAK66271.1 - 0.29 10.8 7.0 0.52 10.0 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function, DUF485 DAGK_cat PF00781.19 GAK66272.1 - 2.1e-13 49.8 0.1 3.7e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 GAK66272.1 - 0.057 12.1 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase SMC_N PF02463.14 GAK66273.1 - 1.3e-69 233.8 0.0 1.9e-69 233.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAK66273.1 - 4.8e-29 100.7 0.3 1.6e-28 99.0 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAK66273.1 - 2.8e-16 60.3 3.6 5.5e-08 33.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAK66273.1 - 6.6e-12 45.1 1.8 6.6e-08 32.0 0.1 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 GAK66273.1 - 3.6e-08 33.9 42.1 3.6e-08 33.9 29.2 6.5 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 GAK66273.1 - 0.0027 17.2 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 GAK66273.1 - 0.45 9.6 26.2 0.28 10.3 2.3 5.5 3 2 2 6 6 6 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 GAK66273.1 - 3.8 7.8 25.6 0.56 10.5 1.2 5.7 3 2 0 3 3 3 0 ABC transporter RRM_1 PF00076.17 GAK66274.1 - 3.4e-06 26.6 0.0 7.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66274.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66274.1 - 0.0008 19.2 0.0 0.0027 17.5 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Toxin_51 PF15531.1 GAK66274.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 51 FHA PF00498.21 GAK66275.1 - 4.9e-15 55.4 0.9 9.8e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 FHA domain Spt20 PF12090.3 GAK66275.1 - 0.0075 15.6 3.2 0.0075 15.6 2.2 1.8 2 0 0 2 2 2 1 Spt20 family Tweety PF04906.8 GAK66275.1 - 0.06 11.7 6.2 0.047 12.1 0.4 2.2 2 0 0 2 2 2 0 Tweety DUF1664 PF07889.7 GAK66275.1 - 0.11 12.2 11.1 0.54 10.0 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Bul1_N PF04425.7 GAK66275.1 - 0.16 10.4 8.7 0.0066 15.0 1.3 2.0 2 0 0 2 2 2 0 Bul1 N terminus Mnd1 PF03962.10 GAK66275.1 - 0.38 10.3 25.3 0.015 15.0 1.9 3.2 2 1 1 3 3 3 0 Mnd1 family DUF4407 PF14362.1 GAK66275.1 - 1.4 7.8 30.6 0.0097 14.8 4.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) vMSA PF00695.14 GAK66275.1 - 4.7 6.3 4.3 9.4 5.3 3.0 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus IncA PF04156.9 GAK66275.1 - 8.7 5.8 39.7 0.3 10.6 7.1 3.4 3 1 0 3 3 3 0 IncA protein BRO1 PF03097.13 GAK66279.1 - 4.2e-14 52.0 0.0 5.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain BLOC1_2 PF10046.4 GAK66280.1 - 0.0051 16.9 2.0 0.0051 16.9 1.4 8.9 7 4 2 9 9 9 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 GAK66280.1 - 0.09 12.7 0.2 0.09 12.7 0.1 10.2 9 2 3 12 12 12 0 bZIP transcription factor HAD PF12710.2 GAK66281.1 - 9.4e-18 65.0 0.0 4.1e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAK66281.1 - 2.8e-16 59.2 0.0 5.5e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAK66281.1 - 3.3e-14 53.7 1.5 1e-12 48.9 1.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK66281.1 - 7.2e-14 51.5 0.0 1.8e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAK66281.1 - 0.0028 17.2 0.2 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAK66281.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Neurokinin_B PF03823.9 GAK66281.1 - 0.077 12.7 0.5 0.18 11.5 0.3 1.6 1 0 0 1 1 1 0 Neurokinin B Cut12 PF11500.3 GAK66281.1 - 3 7.5 6.0 31 4.2 0.0 3.0 3 0 0 3 3 3 0 Spindle pole body formation-associated protein Pinin_SDK_memA PF04696.8 GAK66282.1 - 5e-10 39.0 4.5 1.3e-08 34.5 3.7 2.1 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region vWA-TerF-like PF10138.4 GAK66283.1 - 1.4e-08 34.8 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 GAK66283.1 - 5.7e-05 22.9 0.0 0.00056 19.6 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 GAK66283.1 - 0.00076 19.6 0.2 0.0022 18.1 0.1 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain HEAT_EZ PF13513.1 GAK66284.1 - 5.5e-26 90.3 23.0 4.1e-10 39.8 0.0 10.7 9 3 5 14 14 11 6 HEAT-like repeat HEAT PF02985.17 GAK66284.1 - 2.3e-22 77.0 13.7 0.0016 18.3 0.0 10.3 11 0 0 11 11 10 5 HEAT repeat HEAT_2 PF13646.1 GAK66284.1 - 4.3e-19 68.5 4.4 1.5e-05 25.1 0.0 7.5 4 4 6 10 10 10 4 HEAT repeats Vac14_Fab1_bd PF12755.2 GAK66284.1 - 3.7e-11 43.2 0.0 0.00019 21.7 0.2 4.2 2 2 2 4 4 3 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 GAK66284.1 - 4.2e-07 29.7 0.1 2.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 GAK66284.1 - 3.5e-05 23.4 2.9 1.3 8.9 0.0 6.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 GAK66284.1 - 3.6e-05 23.7 1.7 0.056 13.2 0.1 4.9 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 GAK66284.1 - 0.00041 19.1 0.3 1 8.0 0.0 3.5 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 GAK66284.1 - 0.00063 19.1 0.2 9.5 5.4 0.1 5.1 4 2 2 6 6 6 0 CLASP N terminal Proteasom_PSMB PF10508.4 GAK66284.1 - 0.0053 15.0 0.0 0.026 12.8 0.0 1.9 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Cnd3 PF12719.2 GAK66284.1 - 0.0071 15.3 0.1 1.2 8.0 0.1 3.2 2 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Ecm29 PF13001.2 GAK66284.1 - 0.025 13.0 0.0 11 4.3 0.0 3.8 4 0 0 4 4 4 0 Proteasome stabiliser UNC45-central PF11701.3 GAK66284.1 - 0.047 13.3 0.1 0.43 10.2 0.0 2.6 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Homeobox PF00046.24 GAK66284.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox domain CENP-B_dimeris PF09026.5 GAK66284.1 - 0.37 11.0 8.0 1 9.6 5.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 GAK66284.1 - 1.4 8.4 6.2 2.5 7.6 4.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 GAK66284.1 - 3.1 8.1 7.6 7.1 7.0 5.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 GAK66284.1 - 7.4 6.1 6.9 15 5.1 4.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3245 PF11595.3 GAK66284.1 - 8 6.7 6.2 15 5.8 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) RRM_6 PF14259.1 GAK66285.1 - 8e-38 128.2 0.1 6.1e-09 35.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK66285.1 - 1.4e-32 111.1 0.1 1.5e-08 34.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66285.1 - 3.8e-25 87.5 0.0 1.8e-05 24.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAK66285.1 - 0.024 14.4 0.0 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Mito_carr PF00153.22 GAK66286.1 - 6.1e-66 218.1 2.6 5.6e-22 77.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.17 GAK66287.1 - 3.6e-48 164.1 9.1 5.6e-48 163.5 6.1 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 GAK66287.1 - 2.7e-11 43.8 0.0 5.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cpn60_TCP1 PF00118.19 GAK66288.1 - 2.6e-139 465.0 0.1 2.9e-139 464.8 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GIDA PF01134.17 GAK66289.1 - 4.9e-132 440.5 0.0 7.3e-132 439.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 GAK66289.1 - 2.2e-12 46.8 0.0 6e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 GAK66289.1 - 7.1e-08 32.5 0.1 1.9e-07 31.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAK66289.1 - 2.5e-06 26.8 0.7 4.2e-06 26.1 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK66289.1 - 0.00017 20.6 1.9 0.00061 18.7 1.4 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 GAK66289.1 - 0.00031 19.7 3.5 0.03 13.2 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK66289.1 - 0.0026 16.3 2.0 0.066 11.6 0.5 2.7 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 GAK66289.1 - 0.018 14.1 0.3 0.032 13.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 GAK66289.1 - 0.034 14.2 0.3 3.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK66289.1 - 0.13 11.1 0.5 0.94 8.3 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAK66289.1 - 0.14 11.9 0.8 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding PH PF00169.24 GAK66290.1 - 1.1e-06 28.7 0.0 2.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 PH domain SLD3 PF08639.5 GAK66291.1 - 1.3e-09 37.2 0.5 1.7e-09 36.8 0.4 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 Glyco_hydro_31 PF01055.21 GAK66292.1 - 7.9e-133 443.4 1.1 1.3e-132 442.8 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAK66292.1 - 6e-20 70.8 0.0 2.4e-19 68.9 0.0 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like TP_methylase PF00590.15 GAK66293.1 - 1.3e-16 60.9 0.0 3.5e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2335 PF10097.4 GAK66293.1 - 0.024 14.2 0.8 0.065 12.8 0.5 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Sad1_UNC PF07738.8 GAK66294.1 - 6.3e-28 97.2 0.0 1.1e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MFS_1 PF07690.11 GAK66295.1 - 3.2e-11 42.5 52.4 1.6e-09 36.9 35.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Myb_Cef PF11831.3 GAK66296.1 - 2.3e-54 184.0 3.3 2.3e-54 184.0 2.3 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 GAK66296.1 - 3.4e-22 78.2 5.3 2.2e-10 40.4 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAK66296.1 - 9.4e-19 67.2 8.2 3.4e-13 49.4 2.2 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain bZIP_1 PF00170.16 GAK66297.1 - 4.3e-05 23.3 1.6 4.3e-05 23.3 1.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor CRF1 PF10380.4 GAK66297.1 - 0.0022 18.3 0.7 0.0086 16.4 0.5 2.0 1 0 0 1 1 1 1 Transcription factor CRF1 bZIP_2 PF07716.10 GAK66297.1 - 1.5 8.6 9.4 0.11 12.3 2.7 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Uso1_p115_head PF04869.9 GAK66298.1 - 4.2e-57 193.2 0.0 5.3e-54 183.0 0.0 2.6 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Reo_sigmaC PF04582.7 GAK66298.1 - 0.34 10.0 34.6 0.42 9.7 4.9 3.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Spo12 PF05032.7 GAK66299.1 - 0.00024 20.6 0.4 0.00056 19.4 0.3 1.6 1 0 0 1 1 1 1 Spo12 family 3-PAP PF12578.3 GAK66299.1 - 0.053 13.3 0.6 0.14 11.9 0.2 1.9 2 0 0 2 2 2 0 Myotubularin-associated protein EcKinase PF02958.15 GAK66300.1 - 3.1e-26 92.2 0.0 1.9e-25 89.6 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 GAK66300.1 - 3.9e-12 46.4 2.4 7.1e-12 45.5 1.7 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 GAK66300.1 - 1.1e-07 30.8 0.0 1.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) SSrecog PF03531.9 GAK66301.1 - 1.6e-75 253.2 1.0 8e-75 250.9 0.7 1.9 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 GAK66301.1 - 4.6e-25 87.4 0.0 1.4e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF1900 PF08954.6 GAK66302.1 - 1.5e-45 154.1 0.0 2.9e-44 149.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 GAK66302.1 - 1.2e-31 108.1 0.5 2.5e-31 107.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 GAK66302.1 - 8.6e-18 63.4 3.4 4.3e-08 32.7 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PspA_IM30 PF04012.7 GAK66302.1 - 0.00022 20.6 0.7 0.00035 20.0 0.5 1.2 1 0 0 1 1 1 1 PspA/IM30 family NTR2 PF15458.1 GAK66302.1 - 0.03 13.5 0.4 0.046 12.9 0.3 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 TSC22 PF01166.13 GAK66302.1 - 0.21 11.5 0.5 0.41 10.6 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family RNase_T PF00929.19 GAK66303.1 - 8.3e-26 91.2 0.0 9.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease CRAL_TRIO PF00650.15 GAK66304.1 - 8.1e-30 103.4 0.0 1.3e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 GAK66304.1 - 1.8e-09 37.6 0.0 3.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAK66304.1 - 3.9e-08 33.3 0.1 8.6e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Pantoate_transf PF02548.10 GAK66305.1 - 5.6e-83 278.0 1.0 4.1e-78 262.0 0.2 2.6 2 1 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 GAK66305.1 - 0.0013 17.9 0.1 0.0025 17.0 0.0 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Hydrolase PF00702.21 GAK66305.1 - 0.011 16.1 0.0 0.04 14.3 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 GAK66306.1 - 8.1e-08 32.0 7.5 1.3e-07 31.3 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase PF05875.7 GAK66307.1 - 3.8e-80 268.8 4.5 4.4e-80 268.5 3.1 1.0 1 0 0 1 1 1 1 Ceramidase Glyco_hydro_10 PF00331.15 GAK66308.1 - 1.5e-50 172.0 0.0 1.8e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4120 PF13496.1 GAK66308.1 - 0.051 13.5 0.5 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) TrkH PF02386.11 GAK66309.1 - 1.6e-83 280.2 16.9 6.4e-83 278.2 2.6 2.1 2 0 0 2 2 2 2 Cation transport protein Herpes_DNAp_acc PF04929.7 GAK66310.1 - 0.0082 15.1 2.5 0.0071 15.3 1.8 1.1 1 0 0 1 1 1 1 Herpes DNA replication accessory factor RNase_H2-Ydr279 PF09468.5 GAK66310.1 - 0.011 14.9 5.0 0.0097 15.1 3.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Tim54 PF11711.3 GAK66310.1 - 0.021 13.4 3.2 0.022 13.3 2.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GAGA_bind PF06217.7 GAK66310.1 - 0.026 14.5 3.4 0.024 14.6 2.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 GAK66310.1 - 0.052 13.2 17.5 0.067 12.8 12.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.4 GAK66310.1 - 0.16 11.6 17.2 0.87 9.2 11.9 2.0 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AIF_C PF14721.1 GAK66310.1 - 0.61 10.3 5.1 0.69 10.1 3.5 1.3 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3381 PF11861.3 GAK66310.1 - 0.91 9.0 15.5 1.1 8.6 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Peptidase_S49_N PF08496.5 GAK66310.1 - 2.1 8.1 8.3 3.1 7.5 5.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0016 PF01169.14 GAK66311.1 - 1.6e-41 140.3 26.1 1.1e-20 73.5 6.2 2.9 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Saccharop_dh PF03435.13 GAK66311.1 - 1.8e-21 76.5 0.1 2.8e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 GAK66311.1 - 0.00035 20.4 0.0 0.00066 19.6 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAK66311.1 - 0.0087 16.3 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAK66311.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAK66311.1 - 0.018 15.0 0.1 0.059 13.3 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 GAK66311.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TerC PF03741.11 GAK66311.1 - 0.18 11.2 7.6 0.49 9.8 2.5 2.4 2 0 0 2 2 2 0 Integral membrane protein TerC family Frataxin_Cyay PF01491.11 GAK66313.1 - 5.3e-36 122.7 0.0 8e-36 122.1 0.0 1.3 1 0 0 1 1 1 1 Frataxin-like domain DUF3725 PF12523.3 GAK66313.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Aminotran_1_2 PF00155.16 GAK66314.1 - 1.9e-59 201.4 0.0 2.4e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Esterase PF00756.15 GAK66315.1 - 1.4e-48 165.5 0.0 1.6e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 GAK66315.1 - 5.7e-06 26.1 0.0 7.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAK66315.1 - 0.0021 17.0 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 GAK66315.1 - 0.0046 16.2 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAK66315.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 GAK66315.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK66315.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MIF4G PF02854.14 GAK66317.1 - 8.7e-58 195.1 0.7 1.3e-57 194.6 0.5 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 GAK66317.1 - 8.5e-21 73.6 1.1 1.9e-20 72.5 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 GAK66317.1 - 7.2e-09 35.3 0.2 2.2e-08 33.7 0.1 1.8 2 0 0 2 2 2 1 MA3 domain Hydrophobin PF01185.13 GAK66319.1 - 9.2e-17 61.2 11.6 5.8e-16 58.7 8.0 2.5 1 0 0 1 1 1 1 Fungal hydrophobin Cu_amine_oxidN1 PF07833.6 GAK66319.1 - 3 8.2 17.9 0.5 10.7 0.5 4.5 4 1 1 5 5 5 0 Copper amine oxidase N-terminal domain HSP70 PF00012.15 GAK66320.1 - 3.5e-236 784.8 4.1 4.4e-236 784.5 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAK66320.1 - 7.6e-18 64.1 0.6 1.4e-17 63.2 0.4 1.4 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.5 GAK66320.1 - 0.0024 16.7 1.0 0.017 13.9 0.3 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 GAK66320.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 GAK66320.1 - 0.052 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 StbA protein DUF743 PF05332.6 GAK66320.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF743) Ribosomal_S2 PF00318.15 GAK66321.1 - 5.4e-47 159.7 0.0 8.5e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S2 ABC_membrane PF00664.18 GAK66322.1 - 3.1e-68 230.1 17.6 2.3e-40 138.7 2.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAK66322.1 - 5.5e-60 201.6 0.0 8.1e-29 100.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 GAK66322.1 - 9.1e-14 51.2 2.1 0.00022 20.5 0.6 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAK66322.1 - 1.2e-09 38.4 10.6 2.2e-06 27.7 0.5 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 GAK66322.1 - 1.7e-09 38.0 0.0 0.012 15.6 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_22 PF13401.1 GAK66322.1 - 8.8e-09 35.5 0.2 0.075 13.1 0.3 4.8 4 1 0 4 4 4 2 AAA domain AAA_10 PF12846.2 GAK66322.1 - 1.2e-08 34.8 0.7 0.053 12.9 0.0 4.3 4 0 0 4 4 4 2 AAA-like domain AAA_17 PF13207.1 GAK66322.1 - 2.9e-08 34.5 0.0 0.0015 19.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAK66322.1 - 6.9e-07 28.6 0.0 0.023 14.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 GAK66322.1 - 5.5e-06 26.3 0.1 0.052 13.3 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_18 PF13238.1 GAK66322.1 - 1.4e-05 25.3 0.0 0.14 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 GAK66322.1 - 8.3e-05 22.4 0.5 0.51 10.2 0.1 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 GAK66322.1 - 0.00011 21.4 0.2 0.21 10.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_5 PF07728.9 GAK66322.1 - 0.00018 21.2 0.2 1.6 8.4 0.0 3.8 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAK66322.1 - 0.00032 20.1 1.4 3.7 6.9 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.1 GAK66322.1 - 0.00046 19.6 0.4 1.2 8.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 GAK66322.1 - 0.001 18.1 0.0 0.56 9.2 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.13 GAK66322.1 - 0.002 17.7 0.0 0.23 11.0 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 GAK66322.1 - 0.0029 17.5 3.8 1 9.2 0.1 3.3 3 1 0 3 3 2 2 AAA domain AAA_28 PF13521.1 GAK66322.1 - 0.0033 17.3 0.3 2 8.3 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA PF00004.24 GAK66322.1 - 0.0047 17.1 1.4 40 4.4 0.0 4.5 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAK66322.1 - 0.0048 17.0 0.0 3.6 7.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase APS_kinase PF01583.15 GAK66322.1 - 0.015 14.9 0.1 7.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Mg_chelatase PF01078.16 GAK66322.1 - 0.019 14.1 0.0 3 6.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI tRNA_lig_kinase PF08303.6 GAK66322.1 - 0.02 14.7 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 tRNA ligase kinase domain MobB PF03205.9 GAK66322.1 - 0.031 14.0 0.0 8 6.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 GAK66322.1 - 0.046 12.3 0.0 5.9 5.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.20 GAK66322.1 - 0.062 12.8 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 GAK66322.1 - 0.068 12.8 0.1 12 5.5 0.0 3.1 4 0 0 4 4 2 0 NACHT domain Miro PF08477.8 GAK66322.1 - 0.081 13.4 0.0 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein CbiA PF01656.18 GAK66322.1 - 0.12 11.8 0.0 15 4.9 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain KaiC PF06745.8 GAK66322.1 - 0.13 11.3 3.3 28 3.7 0.0 3.3 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.1 GAK66322.1 - 0.13 12.5 0.1 5.3 7.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain Cyclin PF08613.6 GAK66324.1 - 4.3e-10 40.1 0.1 1.2e-09 38.7 0.1 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAK66324.1 - 9.7e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain adh_short PF00106.20 GAK66328.1 - 6.3e-23 81.5 0.2 1.1e-22 80.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK66328.1 - 7e-10 39.0 0.1 1e-09 38.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK66328.1 - 9.8e-08 31.8 0.1 1.6e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAK66328.1 - 5.8e-05 23.1 0.1 0.0001 22.3 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAK66328.1 - 0.0065 15.4 0.1 0.0096 14.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAK66328.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4235 PF14019.1 GAK66328.1 - 3.7 7.4 6.5 3.9 7.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) tRNA-synt_2 PF00152.15 GAK66329.1 - 7.4e-71 238.6 0.0 9.7e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAK66329.1 - 1.1e-11 44.3 0.0 2.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HEAT_2 PF13646.1 GAK66330.1 - 1.2e-37 128.0 56.4 1.3e-09 38.2 0.0 16.2 8 5 10 18 18 18 12 HEAT repeats DUF3554 PF12074.3 GAK66330.1 - 1.8e-36 126.2 5.9 1.7e-34 119.7 1.8 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT PF02985.17 GAK66330.1 - 7.2e-32 106.5 31.8 0.097 12.8 0.0 20.5 23 0 0 23 23 21 8 HEAT repeat HEAT_EZ PF13513.1 GAK66330.1 - 1.8e-25 88.7 52.1 0.0001 22.6 0.0 20.3 18 3 2 20 20 18 8 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAK66330.1 - 6.9e-09 35.9 0.0 1.5 9.2 0.0 8.4 8 2 2 10 10 9 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 GAK66330.1 - 5.2e-07 29.4 3.7 0.44 10.1 0.0 6.3 5 0 0 5 5 4 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 GAK66330.1 - 2.4e-05 24.2 0.0 24 4.6 0.0 7.8 6 1 1 9 9 8 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 GAK66330.1 - 3e-05 22.5 8.1 0.024 12.9 0.0 6.1 6 2 1 7 7 7 2 Adaptin N terminal region Cohesin_HEAT PF12765.2 GAK66330.1 - 3.5e-05 23.6 1.8 1.1 9.2 0.1 4.8 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 GAK66330.1 - 0.00035 19.6 0.1 0.42 9.5 0.0 3.9 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 GAK66330.1 - 0.0027 17.4 16.7 31 4.5 0.0 9.9 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat Membr_traf_MHD PF10540.4 GAK66330.1 - 0.033 13.9 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain RasGEF_N_2 PF14663.1 GAK66330.1 - 0.047 13.6 0.3 42 4.1 0.0 4.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pox_RNA_Pol_19 PF05320.7 GAK66330.1 - 1.1 8.9 6.5 0.62 9.8 2.8 1.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Mito_carr PF00153.22 GAK66331.1 - 7.8e-48 160.1 0.1 5e-15 54.9 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 GAK66331.1 - 0.029 14.2 0.0 9.5 6.2 0.0 2.7 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF719 PF05334.8 GAK66331.1 - 0.092 12.7 0.2 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Anoctamin PF04547.7 GAK66332.1 - 1.1e-111 373.6 0.0 1.5e-111 373.2 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel LSM PF01423.17 GAK66333.1 - 7.8e-15 54.1 0.0 1.7e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 LSM domain GRP PF07172.6 GAK66333.1 - 1.6 9.2 15.4 2.5 8.6 10.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family zf-CCCH_2 PF14608.1 GAK66334.1 - 3.3e-10 39.5 32.9 0.0028 17.6 0.6 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 GAK66334.1 - 0.024 14.7 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Metallothio_Euk PF12749.2 GAK66334.1 - 9.7 6.3 11.3 0.24 11.4 1.6 2.3 2 0 0 2 2 2 0 Eukaryotic metallothionein EF-hand_6 PF13405.1 GAK66337.1 - 4.4e-11 41.7 1.8 5.2e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 GAK66337.1 - 1.9e-10 40.7 0.1 0.00015 21.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAK66337.1 - 9.3e-09 33.9 3.6 0.0001 21.3 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 GAK66337.1 - 1.6e-05 24.0 1.2 0.024 13.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 GAK66337.1 - 9.5e-05 21.9 0.8 0.61 9.7 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 GAK66337.1 - 0.085 12.7 0.0 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF605 PF04652.11 GAK66338.1 - 1.2 8.4 25.8 0.023 14.0 6.4 2.1 2 0 0 2 2 2 0 Vta1 like NAPRTase PF04095.11 GAK66339.1 - 4.3e-54 183.3 0.0 5.9e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family FCD PF07729.7 GAK66339.1 - 0.04 14.2 1.0 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 FCD domain Glyco_transf_90 PF05686.7 GAK66340.1 - 1.1e-27 96.7 1.9 7.9e-24 84.0 0.4 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 UBA_4 PF14555.1 GAK66340.1 - 0.04 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain Transket_pyr PF02779.19 GAK66342.1 - 2e-62 209.8 0.0 3.1e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 GAK66342.1 - 1.7e-60 204.3 0.0 2.2e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Y_phosphatase PF00102.22 GAK66343.1 - 1.6e-51 174.8 0.2 9.2e-27 93.8 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 GAK66343.1 - 0.0023 18.2 0.0 0.038 14.3 0.0 2.7 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 GAK66343.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAK66343.1 - 0.29 11.1 0.1 2.7 8.0 0.1 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate DSPc PF00782.15 GAK66343.1 - 0.31 10.6 0.4 0.66 9.5 0.2 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Cwf_Cwc_15 PF04889.7 GAK66344.1 - 2.2e-58 197.8 16.2 2.5e-58 197.6 11.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BSP_II PF05432.6 GAK66344.1 - 0.0087 15.3 10.2 0.011 15.0 7.1 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) SDA1 PF05285.7 GAK66344.1 - 0.016 14.5 17.1 0.019 14.2 11.9 1.2 1 0 0 1 1 1 0 SDA1 Upf2 PF04050.9 GAK66344.1 - 0.049 13.3 15.5 0.073 12.8 10.8 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Spore_coat_CotO PF14153.1 GAK66344.1 - 0.068 12.6 7.0 0.083 12.3 4.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 GAK66344.1 - 0.1 11.0 16.7 0.12 10.7 11.6 1.1 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 GAK66344.1 - 0.35 8.6 6.4 0.41 8.4 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HNF-1_N PF04814.8 GAK66344.1 - 0.56 10.2 6.1 0.83 9.7 4.2 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Cytomega_UL84 PF06284.6 GAK66344.1 - 0.85 7.9 4.8 0.99 7.7 3.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein NOA36 PF06524.7 GAK66344.1 - 0.9 8.7 13.1 1.3 8.2 9.0 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 GAK66344.1 - 0.97 7.2 22.9 1.2 6.9 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 GAK66344.1 - 1.2 7.6 6.9 1.3 7.6 4.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 GAK66344.1 - 1.6 6.3 4.1 1.6 6.3 2.9 1.1 1 0 0 1 1 1 0 Ycf1 DUF3381 PF11861.3 GAK66344.1 - 2.4 7.6 13.3 4.2 6.8 9.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DDHD PF02862.12 GAK66344.1 - 2.9 7.6 6.6 3.7 7.2 4.6 1.4 1 0 0 1 1 1 0 DDHD domain GET2 PF08690.5 GAK66344.1 - 4.2 6.5 6.8 5.2 6.2 4.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1510 PF07423.6 GAK66344.1 - 4.4 6.5 16.1 6 6.1 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 GAK66344.1 - 4.7 6.8 10.4 8.5 6.0 7.2 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 GAK66344.1 - 6.8 4.5 18.4 9 4.1 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 GAK66344.1 - 9.9 4.9 11.1 14 4.4 7.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FKBP_C PF00254.23 GAK66345.1 - 2.9e-35 120.1 0.0 3.6e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.20 GAK66346.1 - 1.4e-67 227.6 0.0 1.6e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66346.1 - 3.6e-36 124.5 0.0 4.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK66346.1 - 0.00043 19.3 0.0 0.00068 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK66346.1 - 0.011 14.7 0.0 0.031 13.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAK66346.1 - 0.048 13.3 0.6 0.24 11.1 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAK66346.1 - 0.13 11.5 0.1 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL LZ_Tnp_IS66 PF13007.2 GAK66346.1 - 0.44 11.2 4.9 1.1 9.9 3.4 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain UPF0220 PF05255.6 GAK66347.1 - 3.8e-56 188.9 0.4 1e-55 187.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0220) ApbA PF02558.11 GAK66347.1 - 2.3e-26 92.0 0.3 3.4e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAK66347.1 - 3e-25 88.6 0.0 5.3e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.19 GAK66347.1 - 0.04 12.8 0.8 0.12 11.2 0.4 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.16 GAK66347.1 - 0.064 13.0 0.3 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 GAK66347.1 - 0.081 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase polyprenyl_synt PF00348.12 GAK66348.1 - 1.1e-45 155.4 0.0 1.3e-44 151.9 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase DDE_Tnp_IS66_C PF13817.1 GAK66348.1 - 0.17 11.9 1.0 0.99 9.4 0.0 2.5 3 0 0 3 3 3 0 IS66 C-terminal element RNA_pol_Rpb8 PF03870.10 GAK66349.1 - 1.2e-36 125.8 0.4 8.3e-36 123.2 0.3 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb8 E1-E2_ATPase PF00122.15 GAK66350.1 - 2.8e-75 252.3 0.5 2.8e-75 252.3 0.3 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAK66350.1 - 1.1e-33 117.4 0.0 4.9e-33 115.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 GAK66350.1 - 2.3e-32 112.0 0.3 6.3e-32 110.5 0.2 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus HAD PF12710.2 GAK66350.1 - 8.1e-17 62.0 0.0 1.5e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK66350.1 - 2e-12 46.8 0.0 5e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAK66350.1 - 4.1e-12 45.3 0.0 9.4e-12 44.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAK66350.1 - 0.00076 19.1 3.6 0.0065 16.0 2.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAK66350.1 - 0.083 13.0 0.1 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LHC PF00556.15 GAK66350.1 - 0.1 12.4 0.0 0.46 10.3 0.0 2.2 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Med17 PF10156.4 GAK66351.1 - 2.8e-05 22.5 0.1 0.094 10.9 0.0 2.4 2 0 0 2 2 2 2 Subunit 17 of Mediator complex IBN_N PF03810.14 GAK66351.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain Lectin_leg-like PF03388.8 GAK66352.1 - 1.1e-63 214.4 0.1 2.4e-63 213.3 0.0 1.4 2 0 0 2 2 2 1 Legume-like lectin family Lectin_legB PF00139.14 GAK66352.1 - 0.0042 16.4 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain DUF4349 PF14257.1 GAK66352.1 - 0.093 11.9 0.8 0.14 11.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) FAD_binding_4 PF01565.18 GAK66353.1 - 5.4e-12 45.3 0.4 4.5e-05 22.9 0.1 2.8 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.7 GAK66353.1 - 2.5e-07 30.4 0.1 8e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like Bromodomain PF00439.20 GAK66354.1 - 2.7e-21 75.2 0.2 5.4e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 GAK66354.1 - 0.00017 21.2 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 1 Bromodomain associated adh_short_C2 PF13561.1 GAK66355.1 - 3.5e-11 43.3 0.0 2.1e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK66355.1 - 4.8e-11 42.8 0.2 2.3e-09 37.3 0.2 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK66355.1 - 0.00039 20.1 0.1 0.00089 18.9 0.1 1.5 1 0 0 1 1 1 1 KR domain Pyridox_oxidase PF01243.15 GAK66356.1 - 1.2e-11 44.4 0.0 6.2e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GIT_SHD PF08518.6 GAK66357.1 - 8e-27 92.2 7.7 6.6e-16 57.3 0.6 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Myosin_tail_1 PF01576.14 GAK66357.1 - 0.00097 16.9 22.9 0.00097 16.9 15.9 2.3 2 0 0 2 2 2 1 Myosin tail TBPIP PF07106.8 GAK66357.1 - 0.18 11.3 15.9 0.74 9.3 0.6 3.1 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 GAK66357.1 - 0.41 9.8 21.0 0.76 8.9 2.0 2.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 GAK66357.1 - 0.46 10.3 17.8 1.1 9.0 0.5 4.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 GAK66357.1 - 0.77 10.0 12.0 0.099 12.9 0.4 4.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 GAK66357.1 - 1 9.7 20.6 0.43 10.9 3.6 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 GAK66357.1 - 5.6 6.3 22.3 1 8.8 4.9 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) zf-C2H2 PF00096.21 GAK66358.1 - 1.2e-05 25.3 2.6 0.013 15.7 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK66358.1 - 0.0037 17.4 4.0 0.04 14.2 0.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger Alpha-amylase_C PF02806.13 GAK66359.1 - 4.1e-24 84.5 0.1 4.6e-23 81.1 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 GAK66359.1 - 5.3e-17 62.1 0.0 6.6e-14 52.0 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 GAK66359.1 - 8.8e-15 54.5 0.0 2.6e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 GAK66359.1 - 0.029 13.2 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme DUF3180 PF11377.3 GAK66360.1 - 0.059 13.2 0.4 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DUF2529 PF10740.4 GAK66360.1 - 0.086 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) G-patch PF01585.18 GAK66361.1 - 7.5e-09 35.2 1.3 2.1e-08 33.8 0.9 1.8 1 0 0 1 1 1 1 G-patch domain SprA-related PF12118.3 GAK66361.1 - 5.1e-05 22.7 43.8 0.0011 18.4 12.6 2.1 2 0 0 2 2 2 2 SprA-related family G-patch_2 PF12656.2 GAK66361.1 - 0.0061 16.3 0.9 0.0061 16.3 0.6 5.1 3 2 1 4 4 2 1 DExH-box splicing factor binding site TFIIF_alpha PF05793.7 GAK66361.1 - 0.028 12.7 63.0 0.09 11.1 14.6 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 GAK66361.1 - 0.33 9.3 78.0 0.63 8.4 30.5 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF966 PF06136.8 GAK66361.1 - 0.48 9.7 43.0 0.77 9.1 14.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) YL1 PF05764.8 GAK66361.1 - 1 8.9 61.5 1 8.9 19.6 2.3 2 0 0 2 2 2 0 YL1 nuclear protein SR-25 PF10500.4 GAK66361.1 - 1.7 8.0 100.0 0.013 15.0 17.2 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 GAK66361.1 - 4.6 5.4 44.1 1.2 7.3 16.2 2.1 2 0 0 2 2 2 0 Transmembrane protein PPP4R2 PF09184.6 GAK66361.1 - 4.6 6.7 47.8 0.23 10.9 7.9 2.2 2 0 0 2 2 2 0 PPP4R2 DUF572 PF04502.8 GAK66361.1 - 6.9 5.7 56.4 4.7 6.3 18.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Parvo_coat PF00740.13 GAK66361.1 - 8.6 5.1 17.0 2.6 6.9 3.7 2.1 2 0 0 2 2 2 0 Parvovirus coat protein VP2 WD40 PF00400.27 GAK66362.1 - 7.2e-14 51.0 22.3 5.2e-07 29.3 0.1 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 GAK66362.1 - 0.00052 19.8 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain G-alpha PF00503.15 GAK66363.1 - 2.3e-127 424.9 0.0 3.4e-127 424.3 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAK66363.1 - 3e-14 52.6 0.1 2.5e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAK66363.1 - 0.0012 18.0 0.2 0.97 8.5 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAK66363.1 - 0.015 15.8 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 GAK66363.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAK66363.1 - 0.12 12.6 0.0 3.9 7.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Mito_carr PF00153.22 GAK66365.1 - 1.2e-59 198.0 3.6 6.8e-21 73.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RhoGEF PF00621.15 GAK66366.1 - 5.4e-33 114.3 0.0 4e-29 101.7 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain BAR PF03114.13 GAK66366.1 - 4e-11 42.8 1.6 4.4e-11 42.7 0.2 1.6 2 0 0 2 2 2 1 BAR domain Sugar_tr PF00083.19 GAK66367.1 - 3.1e-104 349.0 22.9 3.5e-104 348.8 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK66367.1 - 1.3e-32 112.9 32.6 3.6e-31 108.1 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAK66367.1 - 4.7e-07 28.3 2.9 4.7e-07 28.3 2.0 2.4 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 GAK66368.1 - 8.1e-79 264.9 0.0 1.2e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ADH_N PF08240.7 GAK66368.1 - 7.4e-29 99.7 2.8 1.6e-28 98.6 2.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK66368.1 - 9.4e-14 51.0 0.0 2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding_C PF13193.1 GAK66368.1 - 4.6e-11 43.5 0.1 9.8e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 GAK66369.1 - 2.7e-24 85.0 1.6 4.6e-24 84.2 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK66369.1 - 2.9e-16 59.2 0.0 5.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 GAK66369.1 - 0.0027 18.2 0.0 0.0064 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 GAK66369.1 - 0.0048 16.0 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDZ_2 PF13180.1 GAK66369.1 - 0.021 14.7 1.0 0.18 11.7 0.1 2.8 3 1 1 4 4 4 0 PDZ domain Methyltransf_31 PF13847.1 GAK66369.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain XdhC_C PF13478.1 GAK66369.1 - 0.074 13.3 0.0 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain PDZ PF00595.19 GAK66369.1 - 0.089 12.9 0.1 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) ADH_zinc_N_2 PF13602.1 GAK66369.1 - 0.12 13.3 0.0 0.31 11.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 GAK66369.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Far-17a_AIG1 PF04750.9 GAK66370.1 - 1.1e-46 158.5 1.4 1.6e-46 158.0 1.0 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Abhydrolase_6 PF12697.2 GAK66370.1 - 2.1e-25 89.9 0.6 4.5e-25 88.8 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 GAK66370.1 - 0.0002 20.8 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 GAK66370.1 - 0.001 18.6 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK66370.1 - 0.0013 18.4 0.0 0.0034 17.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sulfatase PF00884.18 GAK66371.1 - 4.7e-56 190.2 0.0 6.3e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 GAK66371.1 - 3.2e-23 81.3 1.5 6.7e-23 80.2 1.0 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 GAK66371.1 - 2.2e-09 37.1 0.0 2.7e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 GAK66371.1 - 0.0038 17.5 0.0 0.0095 16.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 GAK66371.1 - 0.01 14.2 0.0 0.017 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TatD_DNase PF01026.16 GAK66372.1 - 4.3e-35 121.1 0.0 5.6e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Sulfatase PF00884.18 GAK66373.1 - 9.4e-56 189.2 0.2 1.2e-55 188.9 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAK66373.1 - 0.021 14.1 0.1 0.051 12.8 0.0 1.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Transferase PF02458.10 GAK66374.1 - 5.6e-22 77.7 0.0 8.2e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Transferase family DUF4267 PF14087.1 GAK66375.1 - 3.3e-28 97.5 5.0 3.8e-28 97.3 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DoxX_3 PF13781.1 GAK66375.1 - 0.6 10.4 6.4 0.25 11.7 2.1 2.1 2 1 0 2 2 2 0 DoxX-like family DUF2892 PF11127.3 GAK66375.1 - 3.6 7.4 8.3 0.32 10.8 1.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) OTU PF02338.14 GAK66376.1 - 3.6e-14 53.3 0.0 1.2e-13 51.7 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease Zn_Tnp_IS1595 PF12760.2 GAK66376.1 - 0.074 12.8 2.4 0.21 11.4 1.7 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Trypan_PARP PF05887.6 GAK66377.1 - 0.00052 19.8 19.1 0.001 18.9 13.2 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DcuC PF03606.10 GAK66377.1 - 0.0017 16.7 0.8 0.0019 16.4 0.6 1.0 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier EphA2_TM PF14575.1 GAK66377.1 - 0.003 17.9 0.1 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3366 PF11846.3 GAK66377.1 - 0.0059 16.5 0.3 0.0073 16.2 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3366) PgaD PF13994.1 GAK66377.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein DUF4366 PF14283.1 GAK66377.1 - 0.049 13.0 0.4 0.13 11.6 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4231 PF14015.1 GAK66377.1 - 0.051 13.5 0.5 0.066 13.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Vpu PF00558.14 GAK66377.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Vpu protein Herpes_gE PF02480.11 GAK66377.1 - 0.17 10.1 4.5 0.24 9.6 3.1 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF605 PF04652.11 GAK66377.1 - 2 7.7 7.3 1.8 7.8 5.0 1.2 1 0 0 1 1 1 0 Vta1 like PIRT PF15099.1 GAK66377.1 - 2.2 7.5 8.1 3.5 6.8 3.5 2.0 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family F-box PF00646.28 GAK66378.1 - 0.015 14.9 0.0 0.071 12.7 0.0 2.2 1 0 0 1 1 1 0 F-box domain DUF4243 PF14027.1 GAK66379.1 - 0.015 14.8 0.4 0.015 14.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) FAD_binding_4 PF01565.18 GAK66382.1 - 2.7e-27 94.9 0.0 5.7e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 GAK66382.1 - 6.9e-23 81.2 0.0 1.1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain RPE65 PF03055.10 GAK66383.1 - 5.5e-120 401.1 0.1 6.6e-120 400.9 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DEAD PF00270.24 GAK66384.1 - 6.1e-17 61.6 0.0 8.4e-16 57.9 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK66384.1 - 8.4e-17 60.8 0.1 7.4e-15 54.5 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAK66384.1 - 0.0019 18.0 0.0 0.006 16.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit mRNA_triPase PF02940.10 GAK66385.1 - 7.1e-52 176.2 0.3 8.5e-52 176.0 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain FAD_binding_4 PF01565.18 GAK66386.1 - 2.4e-24 85.4 0.9 3.8e-24 84.7 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAK66386.1 - 2e-09 37.1 0.0 3.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3945 PF13101.1 GAK66386.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) ABC_tran PF00005.22 GAK66387.1 - 3.6e-49 166.5 0.1 4.3e-29 101.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 GAK66387.1 - 1.3e-44 152.6 30.8 5.9e-25 88.2 5.7 4.1 5 0 0 5 5 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 GAK66387.1 - 9.2e-09 35.6 1.2 0.0064 16.4 0.1 4.2 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 GAK66387.1 - 2.8e-08 33.1 0.2 0.00092 18.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 GAK66387.1 - 3.5e-08 33.5 0.2 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 SMC_N PF02463.14 GAK66387.1 - 8.4e-08 31.7 7.8 0.013 14.7 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 GAK66387.1 - 1.1e-07 31.5 0.7 0.0016 17.9 0.1 2.9 2 1 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 GAK66387.1 - 1.7e-07 31.7 0.0 0.00019 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAK66387.1 - 2.8e-07 30.1 0.0 0.0082 15.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 GAK66387.1 - 1.6e-06 28.2 19.3 0.00014 21.8 0.3 5.0 4 2 0 4 4 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 GAK66387.1 - 7.5e-05 22.6 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 GAK66387.1 - 0.00012 22.9 0.0 0.18 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAK66387.1 - 0.00014 21.5 0.3 0.36 10.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.4 GAK66387.1 - 0.00019 20.1 0.1 0.23 10.0 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 GAK66387.1 - 0.0002 21.4 0.8 6.9 6.8 0.0 4.2 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 GAK66387.1 - 0.00041 20.0 0.1 1.6 8.4 0.0 2.9 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 GAK66387.1 - 0.00049 19.0 0.0 0.067 12.0 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 GAK66387.1 - 0.00063 20.2 0.6 1.5 9.3 0.1 3.0 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 GAK66387.1 - 0.0012 18.6 1.5 0.02 14.8 0.2 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 GAK66387.1 - 0.0023 17.1 0.0 0.51 9.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 GAK66387.1 - 0.0024 17.5 0.3 1.4 8.5 0.0 3.0 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 GAK66387.1 - 0.0028 17.1 0.0 0.71 9.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 GAK66387.1 - 0.0056 16.3 0.8 0.47 10.2 0.0 3.7 3 0 0 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 GAK66387.1 - 0.0061 16.8 0.0 4.7 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAK66387.1 - 0.0066 15.5 0.3 0.99 8.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 GAK66387.1 - 0.012 15.0 0.2 7.5 5.9 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.8 GAK66387.1 - 0.015 14.2 0.0 4.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 GAK66387.1 - 0.017 15.3 0.1 12 6.1 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 GAK66387.1 - 0.022 14.1 0.0 0.076 12.4 0.0 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 GAK66387.1 - 0.028 14.6 0.1 14 5.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 GAK66387.1 - 0.037 13.8 1.9 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 GAK66387.1 - 0.044 13.4 0.0 0.63 9.6 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase Telomerase_RBD PF12009.3 GAK66387.1 - 0.066 13.1 0.6 0.17 11.7 0.4 1.6 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain PduV-EutP PF10662.4 GAK66387.1 - 0.1 12.0 0.0 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 GAK66387.1 - 0.12 12.1 0.1 26 4.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAK66387.1 - 0.12 12.3 0.0 4 7.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain cobW PF02492.14 GAK66387.1 - 0.2 11.1 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAK66387.1 - 0.27 11.1 3.6 25 4.7 0.0 3.7 3 1 0 3 3 2 0 AAA domain AAA_24 PF13479.1 GAK66387.1 - 0.4 10.2 0.1 21 4.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ECR1_N PF14382.1 GAK66388.1 - 2.7e-05 23.3 0.0 4.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 GAK66388.1 - 0.041 13.8 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Myb_DNA-bind_2 PF08914.6 GAK66389.1 - 4.5e-05 23.1 2.7 0.002 17.8 0.0 2.9 2 1 0 2 2 2 2 Rap1 Myb domain Rap1-DNA-bind PF09197.5 GAK66389.1 - 0.023 15.2 0.8 0.023 15.2 0.5 2.9 2 0 0 2 2 2 0 Rap1, DNA-binding Shugoshin_C PF07557.6 GAK66390.1 - 3.9e-08 32.6 3.1 3.9e-08 32.6 2.1 3.2 3 1 1 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.6 GAK66390.1 - 2.4e-05 23.9 1.2 4.5e-05 23.0 0.8 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Rab5ip PF07019.7 GAK66391.1 - 2.9e-11 43.3 3.5 4.2e-08 33.2 0.1 2.1 2 0 0 2 2 2 2 Rab5-interacting protein (Rab5ip) DUF3099 PF11298.3 GAK66391.1 - 4.1 7.2 5.1 0.7 9.6 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) RRM_1 PF00076.17 GAK66392.1 - 7.4e-34 115.2 0.0 4.1e-18 64.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66392.1 - 1.8e-19 69.2 0.0 1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66392.1 - 2.8e-19 68.8 0.0 1.5e-08 34.4 0.0 2.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAK66392.1 - 0.00017 21.2 0.1 0.081 12.6 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 GAK66392.1 - 0.086 12.3 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain MFS_1 PF07690.11 GAK66393.1 - 3.3e-24 85.2 46.5 3.3e-24 85.2 32.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF829 PF05705.9 GAK66394.1 - 6.9e-25 88.1 0.0 6e-18 65.4 0.0 3.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Hydrolase_6 PF13344.1 GAK66395.1 - 3.7e-22 78.1 0.0 6.3e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAK66395.1 - 2.7e-18 65.4 0.0 6.5e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3617 PF12276.3 GAK66400.1 - 0.078 12.4 0.2 0.15 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) Esterase_phd PF10503.4 GAK66402.1 - 2.2e-15 56.5 0.3 4.1e-15 55.6 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAK66402.1 - 1.3e-14 53.9 1.7 2.1e-14 53.2 1.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAK66402.1 - 2.1e-06 27.5 0.3 3.9e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK66402.1 - 7.1e-05 22.7 0.1 7.1e-05 22.7 0.0 2.7 2 2 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 GAK66402.1 - 0.00072 19.0 0.3 0.0013 18.1 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 GAK66402.1 - 0.01 15.3 3.9 0.016 14.8 1.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Pkinase PF00069.20 GAK66405.1 - 1.8e-38 132.1 0.0 3.3e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66405.1 - 8.7e-13 47.9 0.0 1.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinetochor_Ybp2 PF08568.5 GAK66405.1 - 8.5e-07 27.6 0.0 0.00016 20.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin APH PF01636.18 GAK66405.1 - 1.9e-05 24.5 0.1 1.9e-05 24.5 0.0 3.5 5 0 0 5 5 5 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAK66405.1 - 0.0025 17.4 0.1 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 GAK66405.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAK66405.1 - 2.9 6.5 0.2 4.1 6.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DNA_ligase_A_N PF04675.9 GAK66406.1 - 3e-36 124.8 0.0 5.8e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 GAK66406.1 - 3.5e-34 117.9 0.0 3e-26 92.0 0.0 3.5 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 GAK66406.1 - 1.5e-17 63.7 0.0 6.3e-17 61.7 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region ParA PF10609.4 GAK66407.1 - 2e-30 104.4 0.0 3.5e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAK66407.1 - 7.7e-17 61.3 0.0 1.2e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAK66407.1 - 2.6e-08 33.9 0.0 3.8e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 GAK66407.1 - 2.2e-05 23.6 1.2 0.00014 21.0 0.2 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 GAK66407.1 - 0.00017 20.7 0.1 0.00093 18.3 0.0 2.0 1 1 1 2 2 2 1 ATPase MipZ AAA_26 PF13500.1 GAK66407.1 - 0.00034 20.2 0.2 0.0099 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 GAK66407.1 - 0.00059 19.1 0.1 0.014 14.5 0.0 2.2 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 GAK66407.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DHDPS PF00701.17 GAK66408.1 - 9e-43 145.9 0.0 1e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family 4HBT PF03061.17 GAK66409.1 - 2.2e-10 40.4 0.1 4.3e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 GAK66409.1 - 0.012 15.6 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) HA2 PF04408.18 GAK66410.1 - 2.1e-19 69.4 0.4 4.4e-18 65.1 0.0 3.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAK66410.1 - 4e-13 49.0 0.0 3.6e-12 45.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 GAK66410.1 - 2.5e-11 43.4 0.0 6.8e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 GAK66410.1 - 2.1e-06 27.9 0.0 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 GAK66410.1 - 1.2e-05 24.8 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase KaiC PF06745.8 GAK66410.1 - 0.02 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 GAK66410.1 - 0.024 14.9 0.0 0.024 14.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zip PF02535.17 GAK66411.1 - 0.56 9.1 4.2 1.3 8.0 2.9 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S19e PF01090.14 GAK66412.1 - 5.9e-55 184.5 0.0 7.7e-55 184.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e NRDE PF05742.7 GAK66413.1 - 2.9e-45 154.7 0.0 7.6e-45 153.3 0.0 1.6 1 1 0 1 1 1 1 NRDE protein TFIIS_C PF01096.13 GAK66414.1 - 7.5e-11 41.4 0.2 7.5e-11 41.4 0.2 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAK66414.1 - 1.8e-09 37.1 2.6 1.8e-09 37.1 1.8 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 GAK66414.1 - 0.038 13.8 4.2 1.9 8.3 1.3 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 GAK66414.1 - 0.048 13.9 2.1 7.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.2 GAK66414.1 - 0.052 13.3 3.6 0.68 9.7 0.9 2.2 2 0 0 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 GAK66414.1 - 0.19 11.5 6.1 2.5 7.9 0.0 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon IBR PF01485.16 GAK66414.1 - 0.2 11.5 3.7 0.78 9.6 1.2 2.1 2 0 0 2 2 2 0 IBR domain Elf1 PF05129.8 GAK66414.1 - 0.23 11.2 2.4 1.5 8.5 0.9 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like PHD PF00628.24 GAK66414.1 - 1.6 8.4 9.0 0.34 10.6 2.9 2.2 2 1 0 2 2 2 0 PHD-finger FGGY_N PF00370.16 GAK66415.1 - 2e-72 243.4 0.3 2.7e-72 243.0 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 GAK66415.1 - 7e-64 215.1 1.8 1.7e-63 213.8 0.8 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain WD40 PF00400.27 GAK66416.1 - 1.1e-61 202.5 24.7 2.7e-12 46.0 1.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat AAA PF00004.24 GAK66416.1 - 1.1e-49 167.9 0.0 3.4e-41 140.5 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK66416.1 - 3e-07 30.5 5.3 4.7e-05 23.4 0.0 4.2 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 GAK66416.1 - 2.9e-05 23.5 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 GAK66416.1 - 7e-05 22.8 0.0 0.00027 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 GAK66416.1 - 0.0003 20.6 0.7 0.043 13.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK66416.1 - 0.00068 19.3 0.2 0.0066 16.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 GAK66416.1 - 0.001 18.8 0.0 0.0078 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAK66416.1 - 0.0012 18.9 0.1 0.053 13.6 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 GAK66416.1 - 0.0027 18.0 0.0 0.085 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAK66416.1 - 0.0048 17.7 0.1 0.054 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 GAK66416.1 - 0.023 14.7 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Apc4_WD40 PF12894.2 GAK66416.1 - 0.039 13.4 0.0 0.94 9.0 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TIP49 PF06068.8 GAK66416.1 - 0.083 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 GAK66416.1 - 0.092 12.9 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 GAK66416.1 - 0.1 12.0 0.0 1.5 8.2 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 GAK66416.1 - 0.12 11.6 0.1 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.6 GAK66416.1 - 0.24 11.2 0.0 0.59 10.0 0.0 1.6 1 0 0 1 1 1 0 Torsin CRAL_TRIO_2 PF13716.1 GAK66418.1 - 2.3e-33 115.2 0.0 4e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 GAK66418.1 - 7.9e-25 87.2 0.0 1.9e-24 86.0 0.0 1.6 1 1 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.11 GAK66419.1 - 2.9e-19 68.9 40.7 2.9e-19 68.9 28.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK66419.1 - 8.3e-06 24.6 10.4 8.3e-06 24.6 7.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter LRR_9 PF14580.1 GAK66420.1 - 1.5e-53 180.9 0.3 2.1e-53 180.4 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 GAK66420.1 - 4.3e-14 51.9 12.9 2e-08 33.8 1.6 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 GAK66420.1 - 9.5e-14 50.6 12.4 5.9e-08 32.1 1.0 4.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAK66420.1 - 0.00031 20.4 4.8 0.54 10.4 0.1 4.2 3 2 1 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 GAK66420.1 - 0.057 13.4 5.4 14 6.1 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 GAK66420.1 - 0.094 12.9 2.2 1.4e+02 3.4 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat Suc_Fer-like PF06999.7 GAK66421.1 - 3.1e-24 86.2 0.0 5.5e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Radical_SAM PF04055.16 GAK66421.1 - 6.6e-12 45.9 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Dynein_light PF01221.13 GAK66423.1 - 1.2e-37 127.7 0.2 1.4e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 GAK66423.1 - 0.026 14.0 0.1 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 28 DUF1992 PF09350.5 GAK66424.1 - 8.1e-21 73.6 0.2 2.4e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Glyco_trans_1_4 PF13692.1 GAK66425.1 - 1.9e-18 66.9 1.1 9e-16 58.2 0.0 3.5 4 0 0 4 4 4 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAK66425.1 - 2.8e-11 43.8 11.4 2.8e-11 43.8 7.9 3.1 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 GAK66425.1 - 0.00023 21.3 0.0 0.00052 20.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAK66425.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Prefoldin_2 PF01920.15 GAK66426.1 - 4.1e-18 65.0 4.4 5.5e-18 64.6 3.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 GAK66426.1 - 0.00034 20.2 2.1 0.00049 19.7 1.5 1.3 1 1 0 1 1 1 1 Prefoldin subunit GvpK PF05121.7 GAK66426.1 - 0.00045 19.9 0.7 0.00045 19.9 0.5 2.0 1 1 0 2 2 2 1 Gas vesicle protein K Atg14 PF10186.4 GAK66426.1 - 0.048 12.6 1.0 0.056 12.3 0.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CAP_assoc_N PF14504.1 GAK66426.1 - 0.066 12.9 0.2 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 CAP-associated N-terminal DUF2746 PF10874.3 GAK66426.1 - 0.21 11.7 4.8 0.57 10.3 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2746) DivIC PF04977.10 GAK66426.1 - 0.77 9.2 5.1 2.8 7.4 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF465 PF04325.8 GAK66426.1 - 1.2 8.8 8.1 0.49 10.1 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) TMEM154 PF15102.1 GAK66427.1 - 0.073 12.7 15.0 4.8e+02 0.3 10.4 3.5 1 1 0 1 1 1 0 TMEM154 protein family YL1_C PF08265.6 GAK66429.1 - 1.8e-14 52.9 0.4 1.8e-14 52.9 0.3 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Trypan_PARP PF05887.6 GAK66429.1 - 0.027 14.3 10.0 0.04 13.7 7.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CENP-B_dimeris PF09026.5 GAK66429.1 - 0.27 11.4 3.2 0.47 10.7 2.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Adeno_terminal PF02459.10 GAK66429.1 - 2.2 6.3 6.3 2.5 6.1 4.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SOBP PF15279.1 GAK66429.1 - 3.1 8.0 9.1 3.6 7.8 6.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PI-PLC-X PF00388.14 GAK66430.1 - 8.2e-11 41.5 0.0 1.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Nop14 PF04147.7 GAK66432.1 - 0.041 11.8 2.5 0.051 11.5 1.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 GAK66432.1 - 1.1 8.4 5.0 1.6 7.9 3.4 1.2 1 0 0 1 1 1 0 SDA1 Ebola_NP PF05505.7 GAK66432.1 - 3.4 5.6 5.1 3.9 5.4 3.5 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Peptidase_S10 PF00450.17 GAK66433.1 - 5.1e-107 358.6 0.0 6.3e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 GAK66433.1 - 3.3e-06 27.1 0.0 0.082 12.7 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family PRCC PF10253.4 GAK66434.1 - 6.7e-06 26.9 4.0 6.7e-06 26.9 2.8 4.0 2 2 2 4 4 4 1 Mitotic checkpoint regulator, MAD2B-interacting Foie-gras_1 PF11817.3 GAK66435.1 - 1.3e-33 116.4 0.0 1.2e-32 113.3 0.0 2.6 2 2 1 3 3 3 1 Foie gras liver health family 1 Zn_clus PF00172.13 GAK66437.1 - 7.4e-07 28.9 6.1 0.00083 19.2 0.6 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BBP1_C PF15272.1 GAK66437.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TB2_DP1_HVA22 PF03134.14 GAK66438.1 - 2.6e-27 94.4 9.8 4e-27 93.7 6.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family UPF0227 PF05728.7 GAK66438.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) COesterase PF00135.23 GAK66439.1 - 2e-90 304.0 0.0 2.8e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAK66439.1 - 1.8e-05 24.3 2.5 0.0003 20.4 1.7 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAK66439.1 - 0.0071 15.5 0.1 0.029 13.6 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family EAP30 PF04157.11 GAK66440.1 - 2.6e-48 164.1 0.0 3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Rhomboid PF01694.17 GAK66441.1 - 0.00073 19.5 6.2 0.0082 16.1 1.8 2.4 1 1 1 2 2 2 2 Rhomboid family DER1 PF04511.10 GAK66441.1 - 0.0032 17.0 0.5 0.0045 16.5 0.3 1.2 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 GAK66441.1 - 0.074 13.3 1.6 0.1 12.9 0.2 1.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) HTH_8 PF02954.14 GAK66441.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family TPP1 PF10341.4 GAK66442.1 - 2.7e-11 43.3 0.0 6.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Nucleo_P87 PF07267.6 GAK66442.1 - 4.9 5.7 7.1 7.5 5.1 4.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_L15e PF00827.12 GAK66443.1 - 7.1e-83 276.8 12.9 1.2e-75 253.2 8.3 2.4 2 0 0 2 2 2 2 Ribosomal L15 Ribosomal_L18p PF00861.17 GAK66444.1 - 3.6e-42 143.3 0.4 1.2e-41 141.5 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 GAK66444.1 - 3.3e-31 107.6 3.4 7.7e-31 106.5 2.3 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_S19 PF00203.16 GAK66445.1 - 5.7e-30 102.7 0.2 9.4e-30 102.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 GAK66446.1 - 1.3e-28 99.2 15.5 1.8e-28 98.7 10.7 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 GAK66446.1 - 1.4 8.7 9.2 2 8.2 6.4 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Sigma70_ner PF04546.8 GAK66446.1 - 1.9 8.0 5.0 3.5 7.1 3.5 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 GAK66446.1 - 3.9 7.6 6.3 27 4.9 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cytochrom_C1 PF02167.10 GAK66447.1 - 4.5e-85 284.7 0.0 5.7e-85 284.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 GAK66447.1 - 0.00063 19.8 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 GAK66447.1 - 0.04 14.7 0.0 0.14 12.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c ERCC4 PF02732.10 GAK66448.1 - 3e-26 91.8 0.0 5e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 GAK66448.1 - 3.6e-07 30.2 0.0 1.3e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain ACC_central PF08326.7 GAK66449.1 - 6.2e-210 698.9 0.0 8.2e-210 698.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 GAK66449.1 - 3.3e-170 566.6 0.0 4.5e-170 566.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 GAK66449.1 - 2.3e-53 180.5 0.0 5.5e-53 179.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAK66449.1 - 2.8e-24 85.3 0.1 8e-24 83.8 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAK66449.1 - 3.6e-21 75.1 0.0 1e-19 70.4 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 GAK66449.1 - 5.8e-14 51.4 0.2 1.2e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 GAK66449.1 - 1e-13 51.4 0.0 3.1e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAK66449.1 - 4.9e-06 26.1 0.0 1.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 GAK66449.1 - 0.00033 20.1 0.0 0.00079 18.8 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAK66449.1 - 0.00051 19.4 0.1 0.0021 17.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 GAK66449.1 - 0.0023 17.8 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.1 GAK66449.1 - 0.011 15.4 0.5 0.035 13.8 0.0 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain RimK PF08443.6 GAK66449.1 - 0.023 14.1 0.0 0.18 11.2 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_2 PF12700.2 GAK66449.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Tubulin_C PF03953.12 GAK66449.1 - 0.31 11.0 0.0 0.77 9.8 0.0 1.6 1 0 0 1 1 1 0 Tubulin C-terminal domain Scm3 PF10384.4 GAK66450.1 - 2.3e-19 68.6 0.2 2.3e-19 68.6 0.2 2.1 2 0 0 2 2 2 1 Centromere protein Scm3 DUF1746 PF08508.5 GAK66451.1 - 1.2e-19 70.3 1.3 1.9e-19 69.7 0.9 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Ribosomal_L35Ae PF01247.13 GAK66452.1 - 1.9e-40 136.5 3.1 2.8e-40 135.9 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae zf-C2H2_jaz PF12171.3 GAK66453.1 - 2.1e-08 34.0 0.4 3.5e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAK66453.1 - 0.0053 16.8 0.0 0.0053 16.8 0.0 1.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 GAK66453.1 - 0.0075 16.4 0.2 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 GAK66453.1 - 0.051 13.9 0.4 0.051 13.9 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nucleopor_Nup85 PF07575.8 GAK66454.1 - 2.6e-85 286.7 0.1 1.1e-51 175.7 0.4 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin Frataxin_Cyay PF01491.11 GAK66454.1 - 0.72 9.6 3.3 5.2 6.9 0.2 2.7 2 0 0 2 2 2 0 Frataxin-like domain Rep_fac_C PF08542.6 GAK66455.1 - 4.2e-19 68.3 0.0 8.6e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 GAK66455.1 - 6.1e-17 62.0 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 GAK66455.1 - 1.4e-16 60.5 0.0 2e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 GAK66455.1 - 1e-11 44.2 0.0 1.3e-08 33.9 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAK66455.1 - 4e-06 26.9 0.1 0.028 14.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 GAK66455.1 - 2.1e-05 23.6 0.0 2.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 GAK66455.1 - 2.3e-05 23.5 0.0 5.5e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAK66455.1 - 2.4e-05 24.2 0.0 8.1e-05 22.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK66455.1 - 3.9e-05 23.3 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 GAK66455.1 - 5.9e-05 22.7 0.1 0.00021 20.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAK66455.1 - 8.7e-05 22.5 0.0 0.0025 17.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAK66455.1 - 0.0001 22.0 0.1 0.0014 18.3 0.0 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 GAK66455.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAK66455.1 - 0.0016 18.0 0.1 0.0066 16.0 0.1 1.9 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 GAK66455.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 GAK66455.1 - 0.0039 16.6 0.0 0.013 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAK66455.1 - 0.0044 16.5 0.3 2.9 7.2 0.0 2.9 2 1 1 3 3 3 1 AAA-like domain DEAD PF00270.24 GAK66455.1 - 0.008 15.6 0.1 0.13 11.7 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_3 PF07726.6 GAK66455.1 - 0.011 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAK66455.1 - 0.017 14.0 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 GAK66455.1 - 0.022 14.6 0.0 0.073 12.9 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 GAK66455.1 - 0.042 13.2 0.0 0.091 12.1 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAK66455.1 - 0.049 12.7 0.0 0.41 9.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 GAK66455.1 - 0.049 13.1 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 GAK66455.1 - 0.051 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAK66455.1 - 0.094 12.9 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase WGG PF10273.4 GAK66455.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 1 0 Pre-rRNA-processing protein TSR2 AAA_17 PF13207.1 GAK66455.1 - 0.14 12.9 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain A_deaminase PF00962.17 GAK66456.1 - 2.2e-110 368.6 0.1 2.9e-110 368.2 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DASH_Spc34 PF08657.5 GAK66457.1 - 3.1e-09 36.8 2.5 0.00015 21.5 0.0 2.9 3 0 0 3 3 3 2 DASH complex subunit Spc34 Cyt-b5 PF00173.23 GAK66458.1 - 1.6e-18 66.2 0.0 2.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF605 PF04652.11 GAK66458.1 - 0.99 8.7 9.9 1.3 8.3 6.9 1.1 1 0 0 1 1 1 0 Vta1 like Hamartin PF04388.7 GAK66458.1 - 1 7.9 7.5 1.2 7.6 5.2 1.1 1 0 0 1 1 1 0 Hamartin protein VHS PF00790.14 GAK66459.1 - 5.1e-31 107.1 0.2 1.2e-30 105.9 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 GAK66459.1 - 3.3e-16 58.5 0.1 6.3e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAK66459.1 - 7.1e-16 57.3 0.0 1.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAK66459.1 - 4.6e-12 45.2 0.0 1.2e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.9 GAK66459.1 - 0.00043 20.2 1.9 0.00077 19.3 0.1 2.3 2 0 0 2 2 2 1 GAT domain UIM PF02809.15 GAK66459.1 - 0.0063 15.9 2.8 0.0063 15.9 1.9 2.4 2 0 0 2 2 2 1 Ubiquitin interaction motif Hrs_helical PF12210.3 GAK66459.1 - 0.0079 16.4 1.7 0.012 15.9 0.2 2.0 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF2183 PF09949.4 GAK66460.1 - 8.5e-25 86.6 0.0 3.1e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 GAK66460.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) MTHFR PF02219.12 GAK66461.1 - 1.6e-111 372.0 0.0 2.5e-111 371.3 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3479 PF11965.3 GAK66461.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Skp1 PF01466.14 GAK66462.1 - 3.7e-36 122.9 0.3 6.7e-36 122.1 0.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 GAK66462.1 - 2.8e-24 84.9 0.1 7e-24 83.6 0.1 1.7 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Zn_clus PF00172.13 GAK66462.1 - 1.2e-05 25.1 10.4 2.3e-05 24.2 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Paf1 PF03985.8 GAK66463.1 - 9.2e-37 126.8 31.6 6e-36 124.1 0.0 4.7 2 2 2 4 4 4 2 Paf1 PseudoU_synth_1 PF01416.15 GAK66464.1 - 1.6e-20 73.4 0.0 3.7e-12 46.5 0.0 3.6 3 1 0 3 3 3 2 tRNA pseudouridine synthase DUF1771 PF08590.5 GAK66464.1 - 7.5e-15 54.7 4.2 3.1e-14 52.7 2.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAK66464.1 - 3.1e-07 30.4 0.1 8.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Smr domain HBS1_N PF08938.5 GAK66464.1 - 0.039 14.0 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus tRNA-synt_2 PF00152.15 GAK66465.1 - 8.2e-64 215.4 0.0 1.2e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Neugrin PF06413.6 GAK66465.1 - 1.6e-09 37.9 0.3 3.4e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 Neugrin Oligomerisation PF02410.10 GAK66465.1 - 4.5e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Oligomerisation domain tRNA_anti-codon PF01336.20 GAK66465.1 - 2.4e-06 27.2 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MRP-L20 PF12824.2 GAK66465.1 - 0.017 15.0 2.9 0.024 14.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 NADH-u_ox-rdase PF10785.4 GAK66466.1 - 5.8e-35 119.3 0.2 9.8e-35 118.6 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 GAK66466.1 - 1.4e-13 50.3 0.0 2.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit TPR_11 PF13414.1 GAK66467.1 - 1.5e-14 53.3 5.1 1.8e-08 33.8 0.9 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAK66467.1 - 1.9e-09 36.7 3.7 1.1e-05 25.0 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAK66467.1 - 4.9e-08 32.2 2.1 0.00012 21.5 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAK66467.1 - 7.8e-05 22.9 2.8 0.0039 17.6 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAK66467.1 - 0.00026 20.7 1.3 0.01 15.6 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAK66467.1 - 0.00037 21.0 4.7 0.065 13.9 0.7 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAK66467.1 - 0.00042 19.8 0.0 0.021 14.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAK66467.1 - 0.0052 17.1 0.4 6.2 7.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAK66467.1 - 0.0052 16.4 0.2 4.5 7.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAK66467.1 - 0.041 13.8 0.2 9.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAK66467.1 - 0.057 13.7 0.6 0.057 13.7 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Septum_form PF13845.1 GAK66467.1 - 0.061 12.8 0.1 0.072 12.5 0.1 1.2 1 0 0 1 1 1 0 Septum formation Clat_adaptor_s PF01217.15 GAK66468.1 - 3.7e-55 185.5 1.3 4.3e-55 185.3 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TPR_14 PF13428.1 GAK66469.1 - 4.4e-05 23.7 14.6 0.057 14.0 0.3 4.4 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAK66469.1 - 0.00042 20.9 1.8 0.00042 20.9 1.3 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAK66469.1 - 0.00086 18.9 2.5 2.9 7.5 0.0 3.7 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.1 GAK66469.1 - 0.0013 19.0 11.3 0.0075 16.5 1.6 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAK66469.1 - 0.0023 17.8 2.1 0.0064 16.4 0.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat LppC PF04348.8 GAK66469.1 - 0.0097 14.5 1.0 0.016 13.8 0.6 1.3 1 1 0 1 1 1 1 LppC putative lipoprotein TPR_2 PF07719.12 GAK66469.1 - 0.012 15.4 3.6 0.83 9.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 GAK66469.1 - 0.069 12.3 0.4 0.17 11.0 0.2 1.6 1 1 0 1 1 1 0 Coatomer epsilon subunit DUF2007 PF09413.5 GAK66469.1 - 0.07 12.9 0.6 0.29 10.9 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) TPR_4 PF07721.9 GAK66469.1 - 0.089 13.2 0.8 0.089 13.2 0.5 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAK66469.1 - 0.47 11.0 9.0 31 5.3 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAK66469.1 - 0.57 10.1 5.6 21 5.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Actin PF00022.14 GAK66470.1 - 1.1e-22 79.9 0.0 8.9e-12 44.1 0.0 3.1 3 0 0 3 3 3 3 Actin AA_permease PF00324.16 GAK66471.1 - 1.8e-64 217.8 31.0 2.2e-64 217.5 21.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4599 PF15371.1 GAK66472.1 - 5.4 7.1 10.7 15 5.7 1.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Ctr PF04145.10 GAK66473.1 - 5.8e-09 36.1 12.6 0.00041 20.4 0.2 2.1 1 1 1 2 2 2 2 Ctr copper transporter family PrgI PF12666.2 GAK66473.1 - 1.5 9.0 5.2 5.4 7.2 3.6 1.8 1 1 0 1 1 1 0 PrgI family protein DUF2985 PF11204.3 GAK66473.1 - 2.8 7.7 6.2 1.1 9.0 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) PRP38 PF03371.10 GAK66474.1 - 9.6e-58 194.6 0.0 1.2e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 PRP38 family KAR9 PF08580.5 GAK66474.1 - 5.9 5.0 7.9 7.4 4.7 5.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 WD40 PF00400.27 GAK66475.1 - 9.9e-19 66.4 14.0 5.2e-05 22.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat GHMP_kinases_N PF00288.21 GAK66476.1 - 2.5e-13 49.8 0.1 6.2e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAK66476.1 - 0.00012 22.2 0.0 0.0003 20.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal SAC3_GANP PF03399.11 GAK66477.1 - 2e-65 220.2 0.7 3.2e-65 219.5 0.5 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family BAG PF02179.11 GAK66477.1 - 3.5e-14 52.6 1.6 1.1e-13 51.0 0.9 2.0 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.18 GAK66477.1 - 0.00017 20.9 0.0 0.00046 19.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Frigida PF07899.6 GAK66477.1 - 0.0067 15.2 0.9 0.012 14.3 0.6 1.3 1 0 0 1 1 1 1 Frigida-like protein PCI_Csn8 PF10075.4 GAK66477.1 - 0.0094 15.7 0.1 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 COX5A PF02284.11 GAK66477.1 - 0.06 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Pkinase PF00069.20 GAK66478.1 - 1.8e-55 187.9 0.0 2.5e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66478.1 - 1.2e-19 70.4 0.0 1.9e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAK66478.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 GAK66478.1 - 0.22 11.0 0.2 0.4 10.2 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tim44 PF04280.10 GAK66479.1 - 8.3e-30 103.7 1.0 3.1e-29 101.8 0.0 2.2 2 0 0 2 2 2 1 Tim44-like domain DUF3446 PF11928.3 GAK66480.1 - 0.049 13.8 12.0 0.14 12.3 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF2419 PF10343.4 GAK66481.1 - 0.05 12.8 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2419) Zn_clus PF00172.13 GAK66482.1 - 1.9e-06 27.6 8.7 4.1e-06 26.5 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH_1 PF13423.1 GAK66483.1 - 3e-46 158.2 0.0 4.3e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 GAK66483.1 - 1.1e-24 87.5 0.0 2.2e-22 80.0 0.0 2.4 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 GAK66483.1 - 0.0006 18.9 0.0 0.049 12.7 0.0 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 GAK66483.1 - 0.0094 15.8 0.2 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4647 PF15504.1 GAK66483.1 - 0.25 10.1 9.3 0.38 9.5 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) BTV_NS2 PF04514.7 GAK66483.1 - 2.4 6.9 8.6 4.5 6.0 6.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDP-OH_P_transf PF01066.16 GAK66484.1 - 5.9e-12 45.7 2.7 5.9e-12 45.7 1.9 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Med4 PF10018.4 GAK66486.1 - 7.6e-21 74.3 6.1 1.2e-20 73.7 4.2 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ubiquitin PF00240.18 GAK66487.1 - 9.1e-35 117.8 0.7 1.4e-34 117.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 GAK66487.1 - 5.3e-24 83.7 0.9 9.1e-24 83.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 GAK66487.1 - 8.2e-20 70.2 0.7 1.5e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAK66487.1 - 1.3e-05 25.3 0.1 5e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAK66487.1 - 0.00024 20.8 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAK66487.1 - 0.0011 18.8 0.2 0.0024 17.7 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 GAK66487.1 - 0.003 17.4 0.5 0.0043 16.8 0.3 1.3 1 0 0 1 1 1 1 IBR domain DUF2407 PF10302.4 GAK66487.1 - 0.0087 16.2 0.3 0.012 15.7 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAK66487.1 - 0.071 13.1 0.4 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF2207 PF09972.4 GAK66487.1 - 0.085 11.4 0.1 0.091 11.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plexin_cytopl PF08337.7 GAK66487.1 - 0.11 10.7 1.5 2.6 6.2 0.0 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DEAD PF00270.24 GAK66488.1 - 6.8e-43 146.0 0.0 1.1e-41 142.1 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK66488.1 - 7.4e-23 80.2 0.0 2.9e-22 78.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC PF00098.18 GAK66488.1 - 0.0023 17.7 0.5 0.0039 17.0 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL32 PF06070.6 GAK66488.1 - 0.019 13.4 2.9 0.027 12.9 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 FdhE PF04216.7 GAK66488.1 - 0.044 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-CCHC_4 PF14392.1 GAK66488.1 - 0.084 12.5 0.5 0.18 11.4 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1253 PF06862.7 GAK66488.1 - 0.086 11.2 0.3 1 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Phage_endo_I PF05367.6 GAK66488.1 - 0.088 12.2 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 Phage endonuclease I DUF2608 PF11019.3 GAK66488.1 - 0.12 11.3 0.3 0.3 10.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) zf-CCHC_2 PF13696.1 GAK66488.1 - 0.15 11.6 0.3 0.38 10.2 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle RINGv PF12906.2 GAK66489.1 - 8.8e-15 54.4 10.7 1.5e-14 53.7 7.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 GAK66489.1 - 0.41 10.5 11.4 0.74 9.6 7.9 1.4 1 0 0 1 1 1 0 Ring finger domain Rad9 PF04139.8 GAK66490.1 - 3.3e-52 177.1 0.0 4.2e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 Trp_syntA PF00290.15 GAK66491.1 - 3.9e-88 294.3 0.1 6.7e-88 293.5 0.1 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 GAK66491.1 - 2.6e-46 158.2 0.1 4.5e-46 157.4 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 GAK66491.1 - 0.014 14.7 0.3 0.05 12.8 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein Pkinase PF00069.20 GAK66492.1 - 4e-72 242.5 0.0 5.1e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66492.1 - 5.6e-47 159.9 0.0 7.8e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAK66492.1 - 8.9e-22 77.2 0.0 2.3e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 GAK66492.1 - 9.5e-06 24.7 0.0 2.7e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 GAK66492.1 - 0.0064 16.2 0.3 0.19 11.4 0.2 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family DSHCT PF08148.7 GAK66492.1 - 0.028 13.6 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 GAK66492.1 - 0.15 11.1 0.3 0.79 8.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 GAK66492.1 - 0.16 11.1 0.1 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RhoGAP PF00620.22 GAK66493.1 - 5.3e-46 155.9 0.0 9.6e-46 155.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 GAK66493.1 - 2e-14 53.4 0.1 1.5e-13 50.7 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HLH PF00010.21 GAK66494.1 - 1.8e-08 33.9 0.6 3.8e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain NBP1 PF08537.5 GAK66494.1 - 0.00068 18.9 1.6 0.0011 18.2 1.1 1.2 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 DUF3135 PF11333.3 GAK66494.1 - 0.083 13.0 0.7 0.2 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) DUF202 PF02656.10 GAK66496.1 - 3.7e-12 46.2 0.6 3.7e-12 46.2 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PITH PF06201.8 GAK66497.1 - 4.7e-35 120.5 0.0 8.3e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 GAK66497.1 - 3.4e-21 74.8 0.2 1.1e-20 73.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAK66497.1 - 0.00059 19.9 0.1 0.12 12.6 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAK66497.1 - 0.00083 19.4 0.2 0.27 11.3 0.1 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 GAK66497.1 - 0.033 14.2 0.6 0.17 11.9 0.4 2.2 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 GAK66497.1 - 0.063 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Peptidase_C97 PF05903.9 GAK66498.1 - 4e-36 124.0 0.0 6.8e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 GAK66498.1 - 1.7e-22 79.4 0.4 3e-22 78.6 0.3 1.4 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 GAK66498.1 - 8.5e-10 38.2 0.0 2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAK66498.1 - 0.0013 18.8 0.0 0.0039 17.3 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain SSF PF00474.12 GAK66499.1 - 3.5e-22 78.6 32.3 5.1e-22 78.0 22.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family An_peroxidase PF03098.10 GAK66500.1 - 1.4e-82 277.8 0.0 8e-81 272.0 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 GAK66500.1 - 0.15 10.5 0.1 0.33 9.4 0.0 1.5 2 0 0 2 2 2 0 Cytochrome P450 zf-HIT PF04438.11 GAK66501.1 - 2.3e-09 36.7 10.1 3.7e-09 36.0 7.0 1.3 1 0 0 1 1 1 1 HIT zinc finger Gar1 PF04410.9 GAK66502.1 - 1.8e-39 134.6 0.3 1.8e-39 134.6 0.2 2.4 1 1 2 3 3 3 1 Gar1/Naf1 RNA binding region OPT PF03169.10 GAK66503.1 - 6.5e-162 540.1 35.6 7.4e-162 539.9 24.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein VIT1 PF01988.14 GAK66503.1 - 0.034 13.6 10.2 0.18 11.2 1.0 3.6 4 0 0 4 4 4 0 VIT family SET PF00856.23 GAK66504.1 - 0.17 12.2 3.6 0.19 12.0 2.5 1.1 1 0 0 1 1 1 0 SET domain TP2 PF01254.13 GAK66504.1 - 0.64 10.3 4.6 0.4 11.0 1.9 1.6 1 1 1 2 2 2 0 Nuclear transition protein 2 RR_TM4-6 PF06459.7 GAK66504.1 - 2.2 8.1 14.4 2.4 8.0 10.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.6 GAK66504.1 - 2.5 6.2 17.3 2.9 6.0 12.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DHHW PF14286.1 GAK66504.1 - 6.3 5.9 7.9 7.9 5.6 5.5 1.1 1 0 0 1 1 1 0 DHHW protein Herpes_LMP1 PF05297.6 GAK66504.1 - 8 5.2 6.7 9.1 5.0 4.6 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DnaJ PF00226.26 GAK66505.1 - 4.4e-23 80.8 0.2 7.1e-23 80.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain UQ_con PF00179.21 GAK66506.1 - 1.1e-20 73.4 0.0 1.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAK66506.1 - 0.0076 16.1 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain SHR3_chaperone PF08229.6 GAK66508.1 - 8.1e-28 96.7 0.0 1.1e-27 96.2 0.0 1.2 1 1 0 1 1 1 1 ER membrane protein SH3 SecG PF03840.9 GAK66508.1 - 0.027 14.1 0.3 0.027 14.1 0.2 1.7 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Pribosyltran PF00156.22 GAK66511.1 - 3.5e-16 59.0 0.1 5.3e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAK66511.1 - 0.001 18.3 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RPN7 PF10602.4 GAK66512.1 - 1.7e-54 183.8 1.5 3.2e-54 182.9 1.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 GAK66512.1 - 8.3e-16 58.2 0.1 3.4e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 PCI domain RRM_1 PF00076.17 GAK66512.1 - 1.9e-13 49.8 0.0 3.9e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66512.1 - 1.2e-11 44.4 0.1 7.5e-11 41.8 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66512.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP PF03399.11 GAK66512.1 - 0.035 13.6 0.4 0.056 12.9 0.3 1.3 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family efThoc1 PF11957.3 GAK66513.1 - 1.2e-94 317.5 1.9 2.6e-45 154.8 1.6 3.8 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor KTSC PF13619.1 GAK66514.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 KTSC domain PGG PF13962.1 GAK66515.1 - 0.66 9.6 4.9 1.5 8.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function PfkB PF00294.19 GAK66516.1 - 7.7e-36 123.7 0.2 9.2e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Aminotran_1_2 PF00155.16 GAK66517.1 - 7.5e-87 291.6 0.0 8.6e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.19 GAK66519.1 - 6.3e-86 288.7 20.5 7.7e-86 288.4 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK66519.1 - 1.1e-17 63.7 44.9 1.2e-16 60.4 12.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily SMC_Nse1 PF07574.8 GAK66520.1 - 1.3e-13 50.9 1.4 2.8e-11 43.4 0.1 2.2 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 GAK66520.1 - 1.8e-05 24.6 5.3 4.9e-05 23.2 3.7 1.7 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H_2 PF13832.1 GAK66520.1 - 0.001 19.0 1.2 0.0025 17.7 0.8 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAK66520.1 - 0.0011 19.0 2.9 0.0026 17.8 2.0 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING_2 PF13639.1 GAK66520.1 - 0.21 11.4 6.6 0.7 9.7 4.6 2.0 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 GAK66520.1 - 0.34 10.7 4.0 0.98 9.3 2.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 GAK66520.1 - 0.38 10.5 6.7 0.21 11.3 3.0 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 GAK66520.1 - 3.6 7.7 7.1 4.4 7.4 3.5 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger ubiquitin PF00240.18 GAK66521.1 - 1.9e-69 228.9 6.6 3.1e-34 116.1 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 GAK66521.1 - 1.6e-39 133.4 6.4 3.4e-19 68.3 0.5 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAK66521.1 - 1.5e-12 47.5 1.5 0.0001 22.4 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAK66521.1 - 3.5e-10 39.8 0.1 0.00081 19.1 0.0 2.2 2 0 0 2 2 2 2 Telomere stability and silencing zf-AN1 PF01428.11 GAK66521.1 - 2.2e-09 37.0 8.3 4.9e-09 35.9 5.7 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD_2 PF13881.1 GAK66521.1 - 3.2e-07 30.2 0.3 0.022 14.6 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAK66521.1 - 1.4e-06 28.4 0.4 0.035 14.3 0.1 2.3 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAK66521.1 - 9e-05 22.4 0.0 0.71 9.9 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 GAK66521.1 - 0.0017 18.0 0.5 2.3 8.0 0.0 2.4 2 0 0 2 2 2 2 FlgD Ig-like domain Methyltrans_RNA PF04452.9 GAK66521.1 - 0.0023 17.1 0.3 0.65 9.0 0.0 2.7 2 1 0 3 3 3 1 RNA methyltransferase TUG-UBL1 PF11470.3 GAK66521.1 - 0.0047 16.8 0.4 3.9 7.4 0.0 2.5 2 0 0 2 2 2 2 GLUT4 regulating protein TUG Plexin_cytopl PF08337.7 GAK66521.1 - 0.0088 14.4 2.7 2.5 6.2 0.2 3.3 3 1 0 3 3 3 1 Plexin cytoplasmic RasGAP domain IBR PF01485.16 GAK66521.1 - 0.071 13.0 3.4 0.12 12.2 2.4 1.3 1 0 0 1 1 1 0 IBR domain Tash_PEST PF07708.6 GAK66521.1 - 0.19 11.7 10.5 2.5 8.1 1.2 2.3 2 0 0 2 2 2 0 Tash protein PEST motif DUF2207 PF09972.4 GAK66521.1 - 0.27 9.7 2.5 6.6 5.1 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FERM_N PF09379.5 GAK66521.1 - 0.32 11.0 1.9 55 3.9 0.1 3.7 3 2 0 3 3 3 0 FERM N-terminal domain Myosin_head PF00063.16 GAK66522.1 - 2.7e-244 812.3 0.5 4.8e-244 811.5 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 GAK66522.1 - 4.2e-35 119.7 1.6 1.2e-34 118.2 1.1 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 GAK66522.1 - 2.5e-18 63.8 28.5 4.5e-05 22.7 0.1 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.1 GAK66522.1 - 0.0026 17.8 0.0 0.013 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain PIN PF01850.16 GAK66522.1 - 0.028 14.7 2.5 0.075 13.3 1.5 1.9 1 1 0 1 1 1 0 PIN domain TPR_MLP1_2 PF07926.7 GAK66522.1 - 0.043 13.5 18.5 0.078 12.7 3.0 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 GAK66522.1 - 0.24 11.2 16.1 0.078 12.8 3.6 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1192 PF06698.6 GAK66522.1 - 0.89 9.4 12.4 0.8 9.5 4.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF972 PF06156.8 GAK66522.1 - 1.6 9.0 8.5 8.9 6.7 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HEAT_EZ PF13513.1 GAK66523.1 - 4.3e-30 103.4 10.6 8.3e-06 26.1 0.0 11.5 10 2 1 11 11 11 6 HEAT-like repeat HEAT_2 PF13646.1 GAK66523.1 - 9.5e-25 86.7 14.8 5e-06 26.7 0.0 8.6 5 4 4 9 9 9 7 HEAT repeats HEAT PF02985.17 GAK66523.1 - 2.2e-19 67.7 14.6 0.0052 16.7 0.1 11.0 13 0 0 13 13 11 4 HEAT repeat UME PF08064.8 GAK66523.1 - 3.3e-10 39.8 0.1 0.00084 19.2 0.0 5.3 4 2 0 4 4 4 2 UME (NUC010) domain IBN_N PF03810.14 GAK66523.1 - 2.2e-09 37.0 0.0 1.2e-08 34.7 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 GAK66523.1 - 5.6e-09 36.2 0.0 0.039 14.3 0.0 5.4 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 GAK66523.1 - 3.8e-08 33.2 0.0 0.11 12.4 0.0 6.3 6 1 1 7 7 7 2 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 GAK66523.1 - 4.7e-08 31.8 2.6 0.33 9.2 0.2 4.6 4 1 0 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.3 GAK66523.1 - 9.7e-07 28.3 0.0 0.12 11.6 0.0 4.7 4 1 0 4 4 4 2 CLASP N terminal Xpo1 PF08389.7 GAK66523.1 - 3.2e-06 27.1 6.9 0.0085 16.0 0.4 6.1 5 1 0 5 5 5 1 Exportin 1-like protein Cohesin_HEAT PF12765.2 GAK66523.1 - 4.7e-05 23.2 1.7 0.01 15.8 0.1 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.3 GAK66523.1 - 0.00017 21.2 0.0 0.04 13.6 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Cnd1 PF12717.2 GAK66523.1 - 0.00078 19.3 0.0 0.93 9.3 0.0 4.2 3 3 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 GAK66523.1 - 0.0024 16.6 2.8 6.4 5.3 0.0 5.2 6 2 2 9 9 9 1 RNAPII transcription regulator C-terminal Arm PF00514.18 GAK66523.1 - 0.011 15.5 11.4 20 5.1 0.0 7.6 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Ric8 PF10165.4 GAK66523.1 - 0.032 13.0 0.5 0.31 9.7 0.0 2.6 3 0 0 3 3 3 0 Guanine nucleotide exchange factor synembryn DUF2435 PF10363.4 GAK66523.1 - 0.066 13.1 0.3 24 4.8 0.0 4.0 4 0 0 4 4 3 0 Protein of unknown function (DUF2435) Bax1-I PF01027.15 GAK66524.1 - 1.5e-32 112.9 9.6 2.2e-32 112.3 6.7 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Cyclin_N PF00134.18 GAK66525.1 - 1.6e-10 40.6 0.2 5.7e-08 32.3 0.0 3.0 3 0 0 3 3 3 2 Cyclin, N-terminal domain TFIIB PF00382.14 GAK66525.1 - 0.00021 21.0 0.0 1.5 8.6 0.0 3.4 2 1 0 2 2 2 2 Transcription factor TFIIB repeat MS_channel PF00924.13 GAK66526.1 - 1.5e-19 70.1 0.4 2.2e-19 69.6 0.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 GAK66526.1 - 0.00033 19.7 0.1 0.00067 18.7 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAK66526.1 - 0.0019 17.9 0.1 0.0051 16.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 GAK66526.1 - 0.0036 16.5 0.2 0.0081 15.4 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 GAK66526.1 - 0.0056 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 GAK66526.1 - 0.028 14.5 0.1 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair RNase_PH PF01138.16 GAK66527.1 - 6e-26 91.3 1.0 1.3e-24 86.9 0.7 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RPN7 PF10602.4 GAK66528.1 - 3.3e-50 169.8 0.0 5.8e-50 169.1 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 GAK66528.1 - 2.3e-12 47.1 0.1 9.7e-12 45.1 0.0 2.1 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 GAK66528.1 - 0.0053 16.5 0.3 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAK66528.1 - 0.01 15.5 0.1 1.4 8.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAK66528.1 - 0.016 14.8 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 0 TPR repeat DUF3703 PF12487.3 GAK66528.1 - 0.12 12.0 0.4 8.9 6.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) AAA PF00004.24 GAK66529.1 - 8.6e-41 139.2 0.0 1.6e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK66529.1 - 0.00012 22.1 0.1 0.0087 16.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 GAK66529.1 - 0.00043 20.2 0.6 0.0043 16.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAK66529.1 - 0.00049 19.8 0.1 0.0052 16.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 GAK66529.1 - 0.00059 19.1 0.4 0.01 15.0 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein RuvB_N PF05496.7 GAK66529.1 - 0.0011 18.0 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAK66529.1 - 0.0016 18.6 2.5 0.02 15.0 0.3 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAK66529.1 - 0.0019 18.9 0.1 0.0069 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAK66529.1 - 0.0083 15.5 1.1 0.14 11.5 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK66529.1 - 0.011 15.4 0.1 0.031 14.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 GAK66529.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAK66529.1 - 0.014 15.3 0.0 0.06 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 GAK66529.1 - 0.014 14.5 0.2 0.048 12.8 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAK66529.1 - 0.02 14.2 0.1 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 GAK66529.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CENP-F_leu_zip PF10473.4 GAK66529.1 - 0.036 13.9 0.7 0.085 12.7 0.5 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_24 PF13479.1 GAK66529.1 - 0.066 12.7 0.1 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 GAK66529.1 - 0.075 12.6 0.1 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0029 PF01205.14 GAK66530.1 - 2.1e-16 59.5 0.1 1.5e-15 56.7 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 Telomere_Sde2_2 PF13297.1 GAK66530.1 - 0.062 12.5 0.4 0.13 11.4 0.3 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal REV PF00424.13 GAK66530.1 - 6.6 6.7 11.2 3.3 7.6 3.1 3.2 2 1 1 3 3 3 0 REV protein (anti-repression trans-activator protein) TFIIF_alpha PF05793.7 GAK66530.1 - 9 4.5 33.2 21 3.3 0.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CLASP_N PF12348.3 GAK66531.1 - 2.1e-80 269.3 2.7 6.4e-69 231.7 0.0 3.4 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.17 GAK66531.1 - 3.6e-07 29.7 1.2 0.56 10.4 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Dopey_N PF04118.9 GAK66531.1 - 0.013 14.2 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Dopey, N-terminal DASH_Duo1 PF08651.5 GAK66532.1 - 0.093 12.3 0.5 11 5.6 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 Pkinase PF00069.20 GAK66533.1 - 2.1e-58 197.5 0.4 3.8e-58 196.6 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66533.1 - 5.5e-22 78.0 0.1 8.3e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAK66533.1 - 0.0093 14.8 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 GAK66533.1 - 0.03 13.6 0.2 0.098 11.9 0.2 1.8 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 GAK66533.1 - 0.11 11.9 0.5 0.62 9.6 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase vMSA PF00695.14 GAK66534.1 - 0.032 13.4 1.2 0.061 12.5 0.8 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus UQ_con PF00179.21 GAK66535.1 - 7.4e-47 158.2 0.0 8.4e-47 158.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAK66535.1 - 0.00083 19.1 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAK66535.1 - 0.12 12.2 0.5 0.14 12.0 0.3 1.5 1 1 0 1 1 1 0 RWD domain Rhodanese PF00581.15 GAK66536.1 - 8.6e-19 67.9 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF1014 PF06244.7 GAK66537.1 - 1.5e-27 96.2 6.6 6.8e-27 94.1 4.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF2852 PF11014.3 GAK66537.1 - 7.4 6.5 8.7 1.1 9.2 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) NAD_kinase PF01513.16 GAK66538.1 - 8.2e-54 182.2 0.0 1.1e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase MFS_1 PF07690.11 GAK66539.1 - 1.4e-28 99.6 24.9 9.4e-28 96.9 17.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.6 GAK66539.1 - 1.3 8.7 11.4 0.032 13.9 0.7 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) GPI2 PF06432.6 GAK66541.1 - 2e-42 145.4 0.1 2.5e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Peptidase_U4 PF03419.8 GAK66541.1 - 0.34 9.9 0.9 0.58 9.1 0.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Lamp PF01299.12 GAK66541.1 - 1.7 7.7 5.1 2.8 7.0 3.6 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Exo5 PF09810.4 GAK66542.1 - 5e-43 147.5 0.0 1.6e-37 129.5 0.0 2.1 1 1 1 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease FAD_binding_4 PF01565.18 GAK66544.1 - 9.7e-22 76.9 0.6 1.6e-21 76.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain PX PF00787.19 GAK66545.1 - 2.4e-20 72.3 0.0 6e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 GAK66545.1 - 8.8e-05 21.8 9.3 0.0013 18.0 0.5 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 GAK66545.1 - 0.1 12.0 7.6 0.05 13.1 0.4 2.2 2 0 0 2 2 2 0 BAR domain PRKCSH PF07915.8 GAK66546.1 - 2.7e-09 37.6 0.3 2.7e-09 37.6 0.2 4.1 4 1 0 4 4 4 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 GAK66546.1 - 0.028 13.8 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Orthopox_F8 PF05886.6 GAK66546.1 - 0.085 12.7 0.1 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Mito_carr PF00153.22 GAK66547.1 - 2.2e-28 97.8 3.7 5.9e-16 57.9 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DNA_pol_B PF00136.16 GAK66548.1 - 2.3e-112 376.1 0.0 3.1e-112 375.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 GAK66548.1 - 2.7e-60 202.9 0.4 4.8e-60 202.1 0.3 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 GAK66548.1 - 2.6e-27 95.5 0.0 3.9e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 GAK66548.1 - 1.8e-17 62.8 9.3 1.8e-17 62.8 6.5 3.1 4 0 0 4 4 4 1 DNA polymerase alpha subunit p180 N terminal Nop14 PF04147.7 GAK66548.1 - 0.016 13.1 7.8 0.024 12.5 5.4 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2841 PF11001.3 GAK66550.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) DUF2015 PF09435.5 GAK66551.1 - 8e-29 100.0 0.4 1.7e-27 95.7 0.0 2.0 1 1 0 2 2 2 2 Fungal protein of unknown function (DUF2015) Kinesin PF00225.18 GAK66552.1 - 4.6e-94 314.8 0.0 7.4e-94 314.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain NHase_beta PF02211.10 GAK66552.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Nitrile hydratase beta subunit DUF1664 PF07889.7 GAK66552.1 - 0.79 9.5 4.7 0.27 11.0 0.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ammonium_transp PF00909.16 GAK66553.1 - 7.8e-104 347.2 26.4 7.8e-104 347.2 18.3 1.9 2 0 0 2 2 2 1 Ammonium Transporter Family Cupin_8 PF13621.1 GAK66554.1 - 7.5e-07 28.9 0.0 2.9e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.24 GAK66554.1 - 1.1e-06 28.1 9.4 2.5e-06 27.0 6.5 1.6 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.17 GAK66554.1 - 2.2e-05 24.6 0.3 0.0013 18.9 0.2 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD_2 PF13831.1 GAK66554.1 - 0.0071 15.6 10.7 0.0071 15.6 7.4 1.8 2 0 0 2 2 2 1 PHD-finger Rad21_Rec8_N PF04825.8 GAK66555.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein HSP9_HSP12 PF04119.7 GAK66555.1 - 8.8 6.4 8.5 6.7 6.8 0.2 4.5 5 0 0 5 5 5 0 Heat shock protein 9/12 DEAD PF00270.24 GAK66557.1 - 2.9e-45 153.7 0.0 6.8e-45 152.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 GAK66557.1 - 7.7e-24 83.0 0.3 1.8e-23 81.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 GAK66557.1 - 3.5e-23 81.2 0.0 9.8e-23 79.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 GAK66557.1 - 0.024 14.6 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain HECT PF00632.20 GAK66558.1 - 3e-76 256.6 0.0 4.1e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3835 PF12927.2 GAK66559.1 - 0.012 16.5 3.1 0.012 16.5 2.1 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF3835) TPR_11 PF13414.1 GAK66560.1 - 1.8e-15 56.3 1.2 2.6e-08 33.3 0.1 5.5 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 GAK66560.1 - 1e-08 34.4 2.1 0.0098 15.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAK66560.1 - 1.6e-07 30.7 13.1 0.00074 19.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAK66560.1 - 9.7e-06 25.3 4.7 0.0013 18.5 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAK66560.1 - 2.1e-05 24.3 0.3 0.00032 20.5 0.1 5.5 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAK66560.1 - 2.7e-05 23.9 0.5 1.3 9.4 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 GAK66560.1 - 3.7e-05 23.7 1.0 0.00027 20.9 0.3 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 GAK66560.1 - 0.00052 19.6 1.9 0.21 11.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAK66560.1 - 0.00054 20.5 2.4 0.0014 19.2 1.6 7.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAK66560.1 - 0.0018 17.9 2.8 6.2 6.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAK66560.1 - 0.039 14.5 0.2 0.039 14.5 0.1 8.7 9 1 1 10 10 8 0 Tetratricopeptide repeat Gastrin PF00918.12 GAK66561.1 - 0.66 10.8 6.1 0.31 11.8 1.6 1.9 1 1 1 2 2 2 0 Gastrin/cholecystokinin family DUF566 PF04484.7 GAK66561.1 - 6.1 6.2 23.7 7.6 5.9 16.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF605 PF04652.11 GAK66561.1 - 7.6 5.8 16.2 9.1 5.5 11.2 1.0 1 0 0 1 1 1 0 Vta1 like Glyco_transf_22 PF03901.12 GAK66563.1 - 4.7e-44 151.0 12.8 5.9e-44 150.7 8.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_L2_C PF03947.13 GAK66564.1 - 1.8e-45 153.8 1.6 5.2e-45 152.4 1.1 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAK66564.1 - 7.3e-26 89.9 0.5 1.5e-25 88.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DnaJ PF00226.26 GAK66564.1 - 4.9e-21 74.2 0.1 1.2e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3166 PF11365.3 GAK66564.1 - 0.77 10.2 5.0 0.58 10.6 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Nsp1_C PF05064.8 GAK66566.1 - 1.2e-29 102.3 0.0 2.5e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 GAK66566.1 - 0.0007 19.8 189.8 0.0089 16.2 28.9 5.5 1 1 4 5 5 5 2 Nucleoporin FG repeat region Baculo_PEP_C PF04513.7 GAK66566.1 - 0.084 12.6 3.1 0.27 11.0 1.1 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TRAUB PF08164.7 GAK66567.1 - 2.7e-26 91.4 2.0 1.3e-25 89.3 0.0 2.8 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 GAK66567.1 - 5.5e-21 75.0 0.8 5.5e-21 75.0 0.6 2.5 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TFIIF_alpha PF05793.7 GAK66567.1 - 0.41 8.9 39.6 0.71 8.1 27.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Atg14 PF10186.4 GAK66567.1 - 4.1 6.2 7.1 13 4.5 2.6 2.3 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Kinesin PF00225.18 GAK66568.1 - 3.4e-96 321.8 0.0 3.4e-96 321.8 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain GAS PF13851.1 GAK66568.1 - 0.0056 15.9 1.9 0.0056 15.9 1.3 3.2 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 GAK66568.1 - 0.01 14.3 17.6 0.017 13.6 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UpxZ PF06603.6 GAK66568.1 - 0.017 15.1 0.0 0.26 11.3 0.0 2.7 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists DMPK_coil PF08826.5 GAK66568.1 - 0.032 14.1 0.3 0.032 14.1 0.2 3.8 3 1 1 4 4 4 0 DMPK coiled coil domain like AAA_24 PF13479.1 GAK66568.1 - 0.051 13.1 0.1 11 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 GAK66568.1 - 0.17 11.0 12.4 0.022 13.9 1.7 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 GAK66568.1 - 1.2 9.0 2.9 16 5.3 0.0 3.8 5 0 0 5 5 5 0 DASH complex subunit Dam1 GP41 PF00517.12 GAK66568.1 - 3.3 7.2 10.1 2 7.9 1.5 2.6 2 1 0 2 2 2 0 Retroviral envelope protein Fib_alpha PF08702.5 GAK66568.1 - 5.4 7.1 12.5 4.5 7.4 5.8 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 GAK66568.1 - 5.7 5.8 28.4 1.2 8.0 6.0 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 GAK66569.1 - 3.9e-41 140.2 25.3 7e-41 139.4 17.5 1.4 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 GAK66569.1 - 6e-09 35.3 23.6 1.6e-05 24.1 8.4 2.3 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 GAK66569.1 - 0.001 18.2 21.7 0.0016 17.7 15.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 GAK66569.1 - 0.0026 17.0 18.8 0.037 13.2 4.4 2.5 2 1 0 3 3 2 2 Protein of unknown function (DUF3450) CENP-K PF11802.3 GAK66569.1 - 0.0043 16.3 0.6 0.0043 16.3 0.4 2.0 1 1 1 2 2 2 1 Centromere-associated protein K SlyX PF04102.7 GAK66569.1 - 0.011 16.0 5.6 1.8 9.0 0.0 2.9 2 1 1 3 3 2 0 SlyX DUF4407 PF14362.1 GAK66569.1 - 0.019 13.9 10.1 0.028 13.3 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 GAK66569.1 - 0.022 14.3 20.8 0.041 13.4 14.4 1.4 1 0 0 1 1 1 0 IncA protein DUF3287 PF11690.3 GAK66569.1 - 0.03 14.4 8.7 0.081 13.0 0.4 2.8 1 1 2 3 3 2 0 Protein of unknown function (DUF3287) Borrelia_P83 PF05262.6 GAK66569.1 - 0.036 12.3 11.2 0.051 11.8 7.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein FlxA PF14282.1 GAK66569.1 - 0.038 13.9 12.5 0.063 13.2 1.0 3.0 1 1 2 3 3 3 0 FlxA-like protein Myosin_tail_1 PF01576.14 GAK66569.1 - 0.058 11.1 21.4 0.086 10.5 14.9 1.3 1 0 0 1 1 1 0 Myosin tail Mod_r PF07200.8 GAK66569.1 - 0.15 11.9 16.5 0.28 11.0 10.0 2.2 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 GAK66569.1 - 0.17 11.0 6.1 0.39 9.8 0.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 GAK66569.1 - 0.19 11.5 22.0 1 9.1 5.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF812 PF05667.6 GAK66569.1 - 0.41 9.0 19.7 1.3 7.4 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) bZIP_1 PF00170.16 GAK66569.1 - 0.42 10.6 15.5 0.47 10.4 2.0 3.5 2 1 1 3 3 3 0 bZIP transcription factor DUF2968 PF11180.3 GAK66569.1 - 0.6 9.4 15.6 0.45 9.8 6.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4140 PF13600.1 GAK66569.1 - 0.66 10.4 16.7 0.9 10.0 3.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LMBR1 PF04791.11 GAK66569.1 - 0.74 8.3 3.1 1.5 7.3 2.1 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein AAA_27 PF13514.1 GAK66569.1 - 0.74 7.4 19.6 0.27 8.8 11.4 1.4 1 1 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 GAK66569.1 - 0.8 9.8 12.2 4.7 7.4 1.7 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.3 GAK66569.1 - 0.88 6.8 20.0 13 2.8 13.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF641 PF04859.7 GAK66569.1 - 0.95 9.2 14.5 0.42 10.3 1.2 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Uso1_p115_C PF04871.8 GAK66569.1 - 1 9.3 23.3 0.14 12.0 13.0 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.4 GAK66569.1 - 1.2 9.0 30.8 0.062 13.1 1.1 3.2 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 GAK66569.1 - 1.2 7.7 18.7 1.1 7.8 11.2 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 GAK66569.1 - 1.2 8.0 24.0 1.9 7.4 7.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 GAK66569.1 - 1.3 9.1 9.3 3.6 7.6 5.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 GAK66569.1 - 1.5 7.1 14.2 1.9 6.8 9.8 1.1 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 GAK66569.1 - 1.7 8.2 17.1 1.3 8.6 9.7 2.0 1 1 1 2 2 2 0 Mnd1 family DUF4559 PF15112.1 GAK66569.1 - 1.9 7.5 12.5 3.4 6.7 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) NPV_P10 PF05531.7 GAK66569.1 - 2 8.6 7.8 2.9 8.2 0.9 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 GAK66569.1 - 2.4 7.6 18.8 4.9 6.6 4.9 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WXG100 PF06013.7 GAK66569.1 - 2.4 8.1 7.1 14 5.8 0.9 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Macoilin PF09726.4 GAK66569.1 - 2.6 6.2 17.7 3.9 5.6 12.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4200 PF13863.1 GAK66569.1 - 2.6 8.0 20.3 0.99 9.3 4.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HAP1_N PF04849.8 GAK66569.1 - 2.8 6.8 19.0 4.4 6.1 13.2 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.3 GAK66569.1 - 2.8 7.8 26.2 2.1 8.2 8.4 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.1 GAK66569.1 - 2.8 7.5 13.2 2.9 7.5 2.0 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.3 GAK66569.1 - 3 7.7 23.2 7.1 6.5 6.7 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.4 GAK66569.1 - 4.1 6.5 15.7 18 4.3 10.8 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 PspA_IM30 PF04012.7 GAK66569.1 - 4.1 6.7 21.7 5 6.4 3.6 2.8 1 1 1 2 2 2 0 PspA/IM30 family DUF4201 PF13870.1 GAK66569.1 - 4.3 6.7 17.8 2.7 7.4 5.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) YlqD PF11068.3 GAK66569.1 - 4.9 7.2 12.6 1.4 8.9 5.5 2.3 1 1 2 3 3 3 0 YlqD protein Spectrin PF00435.16 GAK66569.1 - 4.9 7.4 17.1 0.58 10.4 4.0 3.1 1 1 1 2 2 2 0 Spectrin repeat CCDC155 PF14662.1 GAK66569.1 - 5.2 6.6 23.1 13 5.3 16.0 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 V_ATPase_I PF01496.14 GAK66569.1 - 5.4 4.7 13.3 9.3 3.9 9.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 GAK66569.1 - 5.5 6.9 25.6 8.8 6.3 6.9 2.5 2 1 1 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_GP20 PF06810.6 GAK66569.1 - 5.6 6.3 17.3 8.2 5.8 10.0 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 LRS4 PF10422.4 GAK66569.1 - 5.8 6.1 13.2 9.2 5.5 9.2 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMF_TATA_bd PF12325.3 GAK66569.1 - 5.9 6.6 18.5 7.4 6.3 10.6 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GBP_C PF02841.9 GAK66569.1 - 7.3 5.6 16.6 15 4.6 11.2 1.5 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain HisKA_3 PF07730.8 GAK66569.1 - 8.5 6.8 11.8 27 5.1 2.3 3.8 2 1 1 3 3 2 0 Histidine kinase ERM PF00769.14 GAK66569.1 - 9 5.7 28.1 7.9 5.9 5.9 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3552 PF12072.3 GAK66569.1 - 9.8 5.3 21.3 75 2.4 14.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Response_reg PF00072.19 GAK66570.1 - 1.5e-15 57.1 0.0 2.4e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Amidase PF01425.16 GAK66571.1 - 5.6e-102 341.8 5.3 5.6e-102 341.8 3.7 2.2 2 1 0 2 2 2 1 Amidase FMN_dh PF01070.13 GAK66572.1 - 2.9e-115 384.9 0.0 3.6e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAK66572.1 - 0.00037 19.4 0.7 0.0007 18.5 0.5 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAK66572.1 - 0.00055 19.1 1.2 0.00084 18.5 0.8 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 GAK66572.1 - 0.001 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 GAK66572.1 - 0.0011 18.0 0.0 0.37 9.8 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 GAK66572.1 - 0.021 14.0 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF4646 PF15496.1 GAK66573.1 - 3.7e-34 117.4 0.0 6.8e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) SR-25 PF10500.4 GAK66573.1 - 2.4e-05 23.9 10.0 2.4e-05 23.9 7.0 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 GAK66573.1 - 1.5 6.7 5.0 2.5 6.0 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Phage_B PF02304.10 GAK66573.1 - 6.3 7.1 6.8 0.92 9.8 1.5 2.0 2 0 0 2 2 2 0 Scaffold protein B Melibiase PF02065.13 GAK66574.1 - 2.9e-14 52.5 0.0 1.7e-09 36.8 0.0 2.8 2 1 0 2 2 2 2 Melibiase DUF1971 PF09313.6 GAK66575.1 - 0.23 11.1 2.2 0.26 11.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1971) Coq4 PF05019.8 GAK66576.1 - 7.1e-62 208.2 0.0 8e-50 168.8 0.0 2.1 1 1 1 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ELMO_CED12 PF04727.8 GAK66577.1 - 2.1e-34 118.5 0.0 3e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 GAK66577.1 - 3.1e-08 33.5 0.0 2.7e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) PHF5 PF03660.9 GAK66578.1 - 8.3e-48 160.9 7.3 1e-47 160.6 5.1 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 GAK66578.1 - 0.14 11.9 9.4 1.1 9.1 0.9 2.3 1 1 0 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 GAK66578.1 - 0.79 9.5 12.6 2.5 7.9 0.4 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 GAK66578.1 - 1.3 8.7 12.1 2.8 7.6 0.3 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 GAK66578.1 - 1.5 8.6 8.3 2.9 7.6 4.9 2.3 2 1 0 2 2 2 0 PHD-finger DUF2039 PF10217.4 GAK66578.1 - 1.9 8.5 8.9 0.97 9.4 1.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.7 GAK66578.1 - 3.1 7.6 9.1 49 3.8 5.1 2.3 1 1 1 2 2 2 0 zinc-ribbons TF_Zn_Ribbon PF08271.7 GAK66578.1 - 4.1 6.8 12.4 2.3 7.5 1.1 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding Fungal_trans PF04082.13 GAK66579.1 - 6.2e-15 54.7 0.0 9.7e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK66579.1 - 0.00029 20.6 11.3 0.00054 19.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.14 GAK66580.1 - 1.6e-25 89.5 5.6 2.1e-25 89.2 3.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_L27 PF01016.14 GAK66581.1 - 6.5e-32 109.1 0.2 1e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein KAR9 PF08580.5 GAK66582.1 - 7.3e-05 21.2 0.0 7.3e-05 21.2 0.0 4.6 3 2 0 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.12 GAK66582.1 - 0.0078 15.9 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.16 GAK66582.1 - 0.11 12.8 4.4 5.1 7.4 0.1 3.8 4 0 0 4 4 4 0 Spectrin repeat Glyco_transf_21 PF13506.1 GAK66583.1 - 1.5e-19 69.9 0.3 9.7e-08 31.4 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 GAK66583.1 - 1.3e-10 41.5 0.3 7.6e-10 38.9 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Lyase_1 PF00206.15 GAK66584.1 - 1.2e-95 320.3 0.0 1.7e-95 319.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 GAK66584.1 - 3.5e-28 97.4 0.0 7.4e-28 96.4 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1772 PF08592.6 GAK66587.1 - 3.1e-28 98.2 8.6 3.1e-28 98.2 6.0 2.5 3 1 1 4 4 3 1 Domain of unknown function (DUF1772) Methyltransf_31 PF13847.1 GAK66587.1 - 1.1e-24 86.7 0.0 2.4e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK66587.1 - 1.4e-24 86.4 0.0 2.9e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK66587.1 - 2.3e-16 60.0 0.0 5.9e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK66587.1 - 1.9e-15 56.9 0.0 3.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK66587.1 - 2.2e-15 57.1 0.1 2.1e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK66587.1 - 2.4e-15 56.6 0.0 6.7e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK66587.1 - 6e-14 51.7 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAK66587.1 - 2.9e-09 36.9 0.1 3.4e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAK66587.1 - 6.9e-08 32.0 0.1 1.8e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 GAK66587.1 - 5.9e-07 29.2 0.0 9.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 GAK66587.1 - 0.00016 21.1 0.0 0.0068 15.8 0.0 2.2 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 GAK66587.1 - 0.0002 21.0 0.0 0.00047 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAK66587.1 - 0.00027 20.0 0.0 0.00044 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 GAK66587.1 - 0.00045 19.1 0.0 0.0014 17.5 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_9 PF08003.6 GAK66587.1 - 0.00074 18.3 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_MCEL PF03291.11 GAK66587.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_8 PF05148.10 GAK66587.1 - 0.0023 17.5 0.1 0.017 14.7 0.0 2.0 1 1 0 2 2 2 1 Hypothetical methyltransferase RrnaAD PF00398.15 GAK66587.1 - 0.0028 16.7 0.0 0.0068 15.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase CheR PF01739.13 GAK66587.1 - 0.0029 16.9 0.1 2.1 7.5 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain CMAS PF02353.15 GAK66587.1 - 0.0075 15.3 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 GAK66587.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.8 GAK66587.1 - 0.044 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 GAK66587.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RVT_2 PF07727.9 GAK66588.1 - 5.7e-43 146.6 0.0 1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 GAK66588.1 - 1.9e-27 95.7 0.0 4.4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 GAK66588.1 - 2.5e-13 49.8 0.1 6.2e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 GAK66588.1 - 3.9e-11 42.7 1.4 3.9e-11 42.7 1.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 GAK66588.1 - 4.8e-07 29.3 0.0 1.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotrans_gag PF03732.12 GAK66588.1 - 1e-06 28.6 0.3 3.1e-06 27.1 0.2 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 GAK66588.1 - 5.1e-05 23.0 3.4 5.1e-05 23.0 2.4 2.1 2 0 0 2 2 2 1 Zinc knuckle Alpha-E PF04168.7 GAK66588.1 - 0.00084 18.7 0.6 0.0017 17.8 0.1 1.7 2 0 0 2 2 2 1 A predicted alpha-helical domain with a conserved ER motif. rve_3 PF13683.1 GAK66588.1 - 0.00099 18.5 0.3 0.0039 16.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 GAK66588.1 - 0.0045 16.5 0.3 0.0045 16.5 0.2 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 GAK66588.1 - 0.089 12.3 2.4 0.21 11.0 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Cep57_CLD_2 PF14197.1 GAK66588.1 - 0.7 9.8 3.8 5.9 6.9 0.1 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 gpUL132 PF11359.3 GAK66589.1 - 0.16 11.3 0.5 0.17 11.1 0.4 1.0 1 0 0 1 1 1 0 Glycoprotein UL132 DUF3405 PF11885.3 GAK66590.1 - 1.9e-88 296.8 0.1 7e-47 159.7 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) DUF1361 PF07099.6 GAK66590.1 - 0.003 17.3 0.1 0.0051 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1361) ECH PF00378.15 GAK66591.1 - 1.3e-41 142.3 0.0 4.6e-38 130.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family CopD PF05425.8 GAK66592.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.8 3 1 0 3 3 3 0 Copper resistance protein D Sugar_tr PF00083.19 GAK66594.1 - 2e-75 254.0 15.4 3.1e-75 253.5 10.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK66594.1 - 7.1e-19 67.7 28.4 6.3e-12 44.8 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 GAK66595.1 - 8e-63 208.1 13.2 5.4e-23 80.5 0.3 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein RALF PF05498.6 GAK66595.1 - 0.077 13.8 0.0 3.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Rapid ALkalinization Factor (RALF) PrpF PF04303.8 GAK66596.1 - 6e-86 288.5 0.1 1.1e-85 287.6 0.0 1.3 1 1 0 1 1 1 1 PrpF protein DUF1667 PF07892.6 GAK66596.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Fungal_trans PF04082.13 GAK66597.1 - 4.1e-26 91.4 0.0 8.3e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK66597.1 - 4.5e-07 29.6 17.1 7.1e-07 29.0 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4140 PF13600.1 GAK66597.1 - 0.05 14.0 0.1 0.38 11.2 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AA_permease_2 PF13520.1 GAK66599.1 - 2e-48 165.0 54.3 2.6e-48 164.6 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAK66599.1 - 4.4e-27 94.5 51.5 5.9e-27 94.1 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.21 GAK66601.1 - 8.1e-24 83.6 0.5 1.3e-23 83.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK66601.1 - 4.6e-21 74.6 2.4 3.1e-20 71.9 0.7 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAK66601.1 - 0.089 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2567 PF10821.3 GAK66602.1 - 0.0087 15.5 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) Abhydrolase_5 PF12695.2 GAK66604.1 - 1.6e-22 79.8 0.0 3.6e-22 78.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK66604.1 - 2.7e-18 66.6 0.3 1e-16 61.5 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK66604.1 - 2.1e-11 43.8 0.0 1.1e-06 28.3 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold AXE1 PF05448.7 GAK66604.1 - 1e-06 27.5 0.0 0.002 16.7 0.0 2.4 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 GAK66604.1 - 0.0007 18.9 0.0 0.089 12.0 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAK66604.1 - 0.0041 16.3 0.0 0.045 12.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 GAK66604.1 - 0.0043 16.5 0.0 0.0094 15.4 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 GAK66604.1 - 0.0066 15.9 0.0 0.078 12.3 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 GAK66604.1 - 0.014 15.0 0.0 0.2 11.3 0.0 2.4 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 GAK66604.1 - 0.05 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Peptidase_M76 PF09768.4 GAK66605.1 - 9.3e-66 220.5 0.0 1.2e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 GAK66605.1 - 0.063 12.9 2.1 0.072 12.7 1.0 1.5 1 1 0 1 1 1 0 SprT-like family Rcd1 PF04078.8 GAK66606.1 - 4.9e-128 425.4 1.9 6.2e-128 425.1 1.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like NIT PF08376.5 GAK66606.1 - 0.011 15.2 0.3 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing CRA PF06589.6 GAK66606.1 - 0.088 12.1 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Cyto_heme_lyase PF01265.12 GAK66607.1 - 1.1e-71 241.4 7.1 2.7e-71 240.1 4.9 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PMM PF03332.8 GAK66608.1 - 1.3e-100 335.5 0.7 3.3e-100 334.1 0.5 1.6 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 GAK66608.1 - 2.1e-05 24.2 0.0 0.00027 20.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mre11_DNA_bind PF04152.9 GAK66609.1 - 1.8e-46 158.2 0.6 9.7e-46 155.8 0.0 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 GAK66609.1 - 1.6e-23 83.1 0.3 2.3e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAK66609.1 - 9.5e-07 28.7 0.1 4.2e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Siah-Interact_N PF09032.6 GAK66609.1 - 0.011 15.7 0.6 0.053 13.5 0.4 2.1 1 0 0 1 1 1 0 Siah interacting protein, N terminal MSP1_C PF07462.6 GAK66609.1 - 2.1 6.6 4.7 3.7 5.8 3.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF619 PF04768.8 GAK66610.1 - 1.1e-33 116.0 0.3 1.2e-21 76.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF619) Barstar PF01337.13 GAK66610.1 - 0.15 11.9 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Asparaginase_2 PF01112.13 GAK66612.1 - 1.4e-45 155.4 0.4 9.2e-38 129.7 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Pec_lyase_C PF00544.14 GAK66613.1 - 3.5e-19 69.0 1.0 5.6e-19 68.4 0.1 1.8 2 0 0 2 2 2 1 Pectate lyase Beta_helix PF13229.1 GAK66613.1 - 6.6e-05 22.7 1.0 0.00019 21.1 0.7 1.8 1 1 0 1 1 1 1 Right handed beta helix region Collagen PF01391.13 GAK66613.1 - 0.035 13.6 44.9 0.47 10.0 22.4 2.6 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) RR_TM4-6 PF06459.7 GAK66613.1 - 0.077 12.8 21.1 0.12 12.2 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.12 GAK66613.1 - 1.3 7.7 7.6 1.9 7.2 5.2 1.1 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.6 GAK66613.1 - 7.1 5.5 30.2 11 4.9 20.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Acetyltransf_7 PF13508.1 GAK66615.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain UBX PF00789.15 GAK66616.1 - 2.6e-08 33.7 0.0 4.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain DUF2422 PF10337.4 GAK66617.1 - 2.1e-81 274.0 17.9 5.9e-79 265.9 0.2 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 GAK66617.1 - 1.4e-58 198.2 0.0 2.8e-58 197.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 GAK66617.1 - 1.1e-09 38.2 12.8 1.1e-09 38.2 8.9 3.6 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 GAK66617.1 - 0.029 13.0 4.2 0.065 11.8 2.9 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter TnpV PF14198.1 GAK66617.1 - 0.061 13.2 0.0 9.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Transposon-encoded protein TnpV CMAS PF02353.15 GAK66618.1 - 1e-34 119.8 3.1 1.7e-34 119.1 2.2 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 GAK66618.1 - 9.4e-12 44.9 0.1 2.2e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK66618.1 - 1.4e-11 44.2 0.0 7.5e-11 41.8 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK66618.1 - 5.1e-11 42.9 0.0 1.3e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK66618.1 - 8.4e-10 39.2 0.0 6.8e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAK66618.1 - 1.9e-08 33.8 0.0 4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAK66618.1 - 1.5e-07 31.7 0.0 3.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK66618.1 - 3.9e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAK66618.1 - 0.00033 19.7 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 GAK66618.1 - 0.00047 19.3 0.0 0.00077 18.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 GAK66618.1 - 0.0035 17.3 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAK66618.1 - 0.01 15.2 0.0 0.035 13.4 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW RrnaAD PF00398.15 GAK66618.1 - 0.014 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 GAK66618.1 - 0.017 14.2 0.0 0.059 12.4 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family GidB PF02527.10 GAK66618.1 - 0.017 14.2 0.0 0.039 13.0 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G PCMT PF01135.14 GAK66618.1 - 0.026 14.0 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA_U5-meth_tr PF05958.6 GAK66618.1 - 0.072 11.7 0.1 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase DUF938 PF06080.7 GAK66618.1 - 0.078 12.5 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) FtsJ PF01728.14 GAK66618.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_17 PF12692.2 GAK66618.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase PTS_2-RNA PF01885.11 GAK66619.1 - 7.8e-54 181.8 0.0 1.9e-53 180.5 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family tRNA_int_end_N2 PF12928.2 GAK66619.1 - 2.2e-18 65.4 0.0 6.1e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 GAK66619.1 - 0.011 15.2 0.4 0.045 13.2 0.0 2.0 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain SET PF00856.23 GAK66620.1 - 4e-05 23.9 0.0 9.3e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 SET domain V-ATPase_C PF03223.10 GAK66621.1 - 1.1e-121 406.2 0.3 1.2e-121 406.0 0.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF4110 PF13422.1 GAK66621.1 - 0.022 14.5 0.6 0.066 13.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) PSII_Pbs27 PF13326.1 GAK66621.1 - 0.082 12.8 1.5 0.35 10.8 0.0 2.6 2 1 1 3 3 3 0 Photosystem II Pbs27 Imm29 PF15575.1 GAK66621.1 - 0.17 11.4 2.5 5 6.6 1.1 2.5 2 1 0 2 2 2 0 Immunity protein 29 DUF4404 PF14357.1 GAK66621.1 - 0.34 11.3 4.4 4.6 7.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Bacillus_HBL PF05791.6 GAK66621.1 - 0.62 9.4 6.2 0.78 9.0 0.0 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) RRM_1 PF00076.17 GAK66622.1 - 9.1e-16 57.2 0.0 1.9e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66622.1 - 5.8e-09 35.8 0.0 2.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66622.1 - 1.5e-06 27.9 0.0 0.0018 18.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 GAK66623.1 - 7.4e-23 81.2 8.0 1.6e-22 80.2 5.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK66623.1 - 6.1e-12 45.5 3.7 9.4e-12 44.9 2.6 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK66623.1 - 1.5e-09 37.9 0.1 1.8e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cupin_1 PF00190.17 GAK66624.1 - 1.7e-25 89.1 0.1 7.2e-14 51.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 GAK66624.1 - 8e-25 86.1 0.5 1.9e-13 49.6 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 GAK66624.1 - 9.3e-12 44.7 0.3 1.9e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 GAK66624.1 - 7.4e-06 25.2 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 GAK66624.1 - 6.8e-05 22.5 0.1 0.087 12.4 0.0 2.7 2 1 1 3 3 3 2 Cupin MannoseP_isomer PF01050.13 GAK66624.1 - 0.00046 19.8 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.9 GAK66624.1 - 0.014 15.3 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 GAK66624.1 - 0.02 14.3 0.0 4.9 6.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase 2OG-FeII_Oxy_5 PF13759.1 GAK66624.1 - 0.029 14.6 0.2 4.9 7.5 0.1 3.0 2 2 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase GPI PF06560.6 GAK66624.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) GST_N_3 PF13417.1 GAK66625.1 - 3.3e-16 59.2 0.0 6.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK66625.1 - 5.1e-11 42.4 0.0 9.7e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAK66625.1 - 2.8e-07 30.5 0.0 5.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 GAK66625.1 - 0.00056 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 GAK66625.1 - 0.0033 17.2 0.1 0.0056 16.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fasciclin PF02469.17 GAK66626.1 - 1.6e-33 115.4 3.3 3.1e-23 82.1 0.4 2.3 2 0 0 2 2 2 2 Fasciclin domain DUF2580 PF10824.3 GAK66626.1 - 0.034 14.5 1.4 0.034 14.5 1.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2580) Serglycin PF04360.7 GAK66626.1 - 0.93 9.2 14.4 2.5 7.8 10.0 1.8 1 1 0 1 1 1 0 Serglycin Rhomboid PF01694.17 GAK66628.1 - 1e-09 38.5 13.3 1e-09 38.5 9.2 2.0 2 1 0 2 2 2 1 Rhomboid family GHMP_kinases_N PF00288.21 GAK66628.1 - 0.084 12.9 1.5 0.3 11.1 1.0 2.0 1 0 0 1 1 1 0 GHMP kinases N terminal domain RNA_pol_Rpb4 PF03874.11 GAK66629.1 - 1.3e-12 47.7 0.7 4.4e-12 46.0 0.5 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.27 GAK66630.1 - 1.5e-56 186.3 20.6 4.7e-14 51.6 0.2 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 GAK66630.1 - 2.5e-09 37.1 3.0 2.6e-07 30.5 0.2 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAK66630.1 - 2.3e-07 29.3 15.7 0.0073 14.4 0.4 4.7 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 GAK66630.1 - 4.4e-05 22.4 0.1 0.17 10.6 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.1 GAK66630.1 - 0.00027 20.4 1.6 0.0084 15.5 1.1 2.3 1 1 0 1 1 1 1 PQQ-like domain DUF3312 PF11768.3 GAK66630.1 - 0.00083 17.7 1.2 0.023 12.9 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3312) Hira PF07569.6 GAK66630.1 - 0.023 13.8 3.9 0.19 10.9 0.1 3.3 3 1 1 4 4 4 0 TUP1-like enhancer of split DUF1295 PF06966.7 GAK66631.1 - 4.4e-37 127.6 3.7 7.3e-36 123.6 2.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Kinesin PF00225.18 GAK66632.1 - 3.9e-109 364.3 0.4 1.2e-108 362.7 0.3 1.9 1 0 0 1 1 1 1 Kinesin motor domain Baculo_PEP_C PF04513.7 GAK66632.1 - 2.7 7.8 34.6 0.32 10.8 0.2 7.4 2 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus SAICAR_synt PF01259.13 GAK66633.1 - 1.6e-80 269.8 0.0 2e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Kinesin PF00225.18 GAK66634.1 - 2.5e-80 269.7 0.0 4.2e-80 268.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain RIO1 PF01163.17 GAK66635.1 - 4.9e-41 140.1 0.2 1.2e-28 99.7 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 GAK66635.1 - 2e-33 114.3 0.1 4e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 GAK66635.1 - 7.2e-08 32.4 2.9 2e-05 24.4 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 GAK66635.1 - 0.00047 19.2 0.0 0.053 12.5 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family MarR_2 PF12802.2 GAK66635.1 - 0.001 18.6 0.0 0.016 14.8 0.0 2.5 2 0 0 2 2 2 1 MarR family CobT PF06213.7 GAK66635.1 - 0.0031 16.6 19.3 0.0031 16.6 13.4 2.5 2 1 1 3 3 2 1 Cobalamin biosynthesis protein CobT SDA1 PF05285.7 GAK66635.1 - 0.006 15.9 14.5 0.006 15.9 10.1 2.2 2 0 0 2 2 2 1 SDA1 HTH_Crp_2 PF13545.1 GAK66635.1 - 0.032 14.0 0.0 0.097 12.4 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Prothymosin PF03247.9 GAK66635.1 - 0.051 13.7 37.6 0.17 12.0 13.1 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family Phage_rep_O PF04492.8 GAK66635.1 - 0.14 12.4 0.0 0.97 9.6 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage replication protein O Merozoite_SPAM PF07133.6 GAK66635.1 - 0.74 9.6 25.9 0.46 10.3 8.6 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Daxx PF03344.10 GAK66635.1 - 2.7 6.3 31.1 0.19 10.1 11.7 2.3 2 0 0 2 2 2 0 Daxx Family E1_DerP2_DerF2 PF02221.10 GAK66636.1 - 4e-24 85.3 0.0 5.2e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF1180 PF06679.7 GAK66636.1 - 0.047 13.5 0.1 0.058 13.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) TRP_N PF14558.1 GAK66636.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 1 1 2 2 2 0 ML-like domain DUF4625 PF15418.1 GAK66636.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) DUF4098 PF13345.1 GAK66637.1 - 7.4e-11 41.8 1.3 5.5e-06 26.2 0.0 3.8 3 1 1 4 4 4 2 Domain of unknown function (DUF4098) OppC_N PF12911.2 GAK66637.1 - 0.04 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PPR_2 PF13041.1 GAK66638.1 - 1.3e-43 146.7 0.1 1.4e-08 34.5 0.0 6.9 6 1 0 6 6 6 6 PPR repeat family PPR_1 PF12854.2 GAK66638.1 - 5e-28 96.2 3.7 0.0012 18.3 0.0 9.5 9 0 0 9 9 9 7 PPR repeat PPR_3 PF13812.1 GAK66638.1 - 5.4e-27 91.7 22.1 0.0008 19.4 0.0 14.3 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR PF01535.15 GAK66638.1 - 6.4e-18 63.4 13.3 0.00018 21.2 0.0 11.2 12 0 0 12 12 12 3 PPR repeat TPR_19 PF14559.1 GAK66638.1 - 0.0011 19.2 2.5 0.93 9.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat MNE1 PF13762.1 GAK66638.1 - 0.093 12.8 0.0 23 5.0 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial splicing apparatus component TPR_14 PF13428.1 GAK66638.1 - 3.1 8.6 21.6 6.8 7.6 0.0 7.8 6 2 3 9 9 9 0 Tetratricopeptide repeat Snf7 PF03357.16 GAK66639.1 - 8.8e-34 116.3 10.0 1.1e-33 116.0 6.9 1.1 1 0 0 1 1 1 1 Snf7 Gluconate_2-dh3 PF13618.1 GAK66639.1 - 0.2 11.7 3.8 0.13 12.4 1.0 1.9 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF3560 PF12083.3 GAK66639.1 - 0.23 11.4 2.7 0.8 9.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Peptidase_M24 PF00557.19 GAK66642.1 - 8.6e-48 162.6 0.0 1.2e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAK66642.1 - 2.7e-35 120.6 0.0 5.2e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GST_N_3 PF13417.1 GAK66643.1 - 1e-09 38.4 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAK66643.1 - 1e-07 31.7 0.0 3.1e-07 30.1 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAK66643.1 - 1.8e-07 31.0 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAK66643.1 - 1.1e-06 28.5 0.0 6.3e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAK66643.1 - 3.3e-05 23.9 0.0 7.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAK66643.1 - 0.0078 16.6 0.1 0.038 14.4 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_31 PF13847.1 GAK66644.1 - 5.9e-19 68.1 0.0 8.7e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK66644.1 - 7.1e-19 68.1 0.0 2.3e-17 63.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK66644.1 - 1.5e-16 60.5 0.0 2.3e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK66644.1 - 2.2e-14 53.6 0.0 4.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK66644.1 - 2.8e-12 46.9 0.0 4.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK66644.1 - 3.1e-10 39.5 0.0 4.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAK66644.1 - 5.3e-09 36.6 0.1 2.9e-08 34.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK66644.1 - 3.5e-07 30.2 0.0 1.1e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK66644.1 - 0.0082 15.5 0.0 0.27 10.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 GAK66644.1 - 0.017 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 GAK66644.1 - 0.17 10.9 0.1 0.82 8.7 0.1 1.9 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) IlvN PF07991.7 GAK66645.1 - 3.9e-43 146.6 0.0 6e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 GAK66645.1 - 2.1e-42 144.4 0.0 3.5e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 GAK66645.1 - 0.0021 18.4 0.2 0.0071 16.7 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAK66645.1 - 0.042 13.6 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Band_7 PF01145.20 GAK66646.1 - 1.5e-27 96.6 0.6 2.6e-27 95.8 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family DHH PF01368.15 GAK66647.1 - 4.2e-07 29.7 0.0 1e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.9 GAK66647.1 - 1.4e-06 28.5 0.0 4.3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 DHHA2 domain 4HBT_3 PF13622.1 GAK66648.1 - 1.4e-36 126.5 0.5 1.7e-36 126.2 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily WD40 PF00400.27 GAK66649.1 - 5.4e-13 48.2 1.0 0.0032 17.3 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Corona_I PF03187.9 GAK66649.1 - 0.019 14.1 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Corona nucleocapsid I protein FMN_dh PF01070.13 GAK66650.1 - 2.6e-122 408.1 0.4 3.1e-122 407.8 0.3 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAK66650.1 - 2e-22 78.7 0.0 7.4e-22 76.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAK66650.1 - 1.8e-05 23.8 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAK66650.1 - 0.00018 20.5 0.2 0.00031 19.7 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Arm PF00514.18 GAK66650.1 - 0.0021 17.7 0.0 0.0081 15.9 0.0 2.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat ThiG PF05690.9 GAK66650.1 - 0.0028 16.7 0.0 0.85 8.6 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 GAK66650.1 - 0.035 13.3 0.4 0.41 9.8 0.1 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein KaiC PF06745.8 GAK66650.1 - 0.11 11.5 0.0 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 KaiC NAD_binding_8 PF13450.1 GAK66652.1 - 6.1e-10 38.9 0.0 2e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAK66652.1 - 4.1e-06 26.1 0.0 0.043 12.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 GAK66652.1 - 3.1e-05 23.0 0.3 0.011 14.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK66652.1 - 0.00021 21.0 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAK66652.1 - 0.0018 18.3 0.0 0.079 13.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RRS1 PF04939.7 GAK66654.1 - 1.5e-57 193.6 2.6 1.5e-57 193.6 1.8 1.5 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) CPSF100_C PF13299.1 GAK66654.1 - 0.38 10.9 5.5 0.1 12.7 1.3 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal WD40 PF00400.27 GAK66655.1 - 1.1e-46 155.0 17.3 4.7e-11 42.1 0.0 7.7 8 1 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 GAK66655.1 - 0.016 13.3 4.1 0.55 8.2 2.6 3.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TSKS PF15358.1 GAK66655.1 - 0.44 8.6 2.8 0.77 7.8 1.9 1.3 1 0 0 1 1 1 0 Testis-specific serine kinase substrate MIF4G PF02854.14 GAK66656.1 - 3.2e-24 85.5 0.0 2.3e-23 82.7 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 GAK66656.1 - 1.1e-13 50.8 0.0 2.8e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 MA3 domain DEAD PF00270.24 GAK66657.1 - 3.6e-39 133.9 0.0 1.2e-38 132.2 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK66657.1 - 4.8e-26 90.4 0.1 1.8e-25 88.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAK66657.1 - 5e-06 25.5 0.0 1e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAK66657.1 - 8.6e-05 22.4 0.6 0.00061 19.6 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 GAK66657.1 - 0.0027 17.4 0.0 0.014 15.1 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain Herpes_ori_bp PF02399.10 GAK66657.1 - 0.044 11.7 0.0 0.079 10.9 0.0 1.3 1 0 0 1 1 1 0 Origin of replication binding protein DUF1253 PF06862.7 GAK66657.1 - 0.075 11.4 0.0 0.33 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) F-box-like PF12937.2 GAK66658.1 - 8e-09 35.0 1.2 1.7e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 GAK66658.1 - 9.2e-06 25.3 5.6 2.4e-05 24.0 0.5 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat F-box PF00646.28 GAK66658.1 - 6.6e-05 22.4 0.2 0.0002 20.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 GAK66659.1 - 6.1e-64 215.6 0.0 1.1e-63 214.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66659.1 - 1e-40 139.4 0.0 3.3e-37 127.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK66659.1 - 1.3e-07 30.8 0.0 2.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK66659.1 - 0.02 14.6 0.2 0.27 10.9 0.1 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAK66659.1 - 0.045 12.5 0.2 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 GAK66659.1 - 0.046 13.0 0.1 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 GAK66659.1 - 0.065 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zip PF02535.17 GAK66659.1 - 0.38 9.7 7.8 0.83 8.5 5.4 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3534 PF12053.3 GAK66659.1 - 4 7.3 11.2 0.2 11.5 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3534) SelP_N PF04592.9 GAK66659.1 - 4.5 6.5 19.9 0.1 11.9 8.9 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region HTH_3 PF01381.17 GAK66660.1 - 4.1e-15 55.3 0.3 7.2e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 GAK66660.1 - 3.6e-10 39.7 1.7 4.7e-10 39.3 0.2 2.0 2 2 0 2 2 2 1 Multiprotein bridging factor 1 HTH_19 PF12844.2 GAK66660.1 - 9.6e-08 31.9 0.1 1.4e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 GAK66660.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 GAK66660.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Response_reg PF00072.19 GAK66661.1 - 1.7e-20 73.0 0.0 6.1e-20 71.3 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 GAK66661.1 - 1.3e-18 66.7 0.4 3e-18 65.5 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAK66661.1 - 1.7e-07 31.1 0.9 4.9e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 GAK66661.1 - 1e-05 25.6 0.0 0.0001 22.4 0.0 2.4 2 0 0 2 2 2 1 GAF domain DUF1664 PF07889.7 GAK66661.1 - 0.048 13.4 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-ZPR1 PF03367.8 GAK66662.1 - 1.5e-104 346.0 0.6 5.4e-52 175.1 0.0 3.1 3 0 0 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 GAK66662.1 - 0.0028 17.3 3.0 0.38 10.4 0.3 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 GAK66662.1 - 0.044 13.0 5.1 1.3 8.3 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 GAK66662.1 - 0.073 12.9 6.0 0.73 9.6 0.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon Cytochrome_C554 PF13435.1 GAK66662.1 - 0.1 12.6 1.8 10 6.1 0.4 2.5 2 0 0 2 2 2 0 Cytochrome c554 and c-prime TBCA PF02970.11 GAK66662.1 - 0.12 12.4 0.2 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A UPF0547 PF10571.4 GAK66662.1 - 0.17 11.6 2.4 2 8.2 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 GAK66662.1 - 0.45 10.2 4.2 7.4 6.3 0.2 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 GAK66662.1 - 0.62 9.6 7.8 0.74 9.3 0.3 3.2 2 1 1 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 GAK66662.1 - 0.7 9.8 6.7 9.6 6.2 0.1 3.8 4 0 0 4 4 4 0 Zinc ribbon domain Lar_restr_allev PF14354.1 GAK66662.1 - 1.2 9.4 6.5 30 4.9 0.1 3.8 3 1 0 3 3 3 0 Restriction alleviation protein Lar Pro_isomerase PF00160.16 GAK66663.1 - 6.2e-41 140.1 0.0 1.4e-40 139.0 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 GAK66663.1 - 1.5e-09 37.4 0.1 7.9e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger SPX PF03105.14 GAK66664.1 - 2e-55 188.5 2.6 3.4e-55 187.7 1.8 1.4 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 GAK66664.1 - 1.1e-29 103.6 37.5 1.5e-29 103.2 26.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 GAK66664.1 - 6.7e-19 67.6 36.6 4.2e-13 48.5 13.5 2.2 1 1 1 2 2 2 2 Citrate transporter WD40 PF00400.27 GAK66665.1 - 1.1e-37 126.5 7.3 1.8e-09 37.0 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAK66665.1 - 5.3e-32 109.5 1.4 1.1e-31 108.5 1.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 GAK66665.1 - 0.0005 19.5 0.0 0.031 13.7 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 GAK66665.1 - 0.14 10.2 1.1 1.1 7.3 0.0 2.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 NAP PF00956.13 GAK66666.1 - 3.7e-40 137.5 0.5 3.7e-40 137.5 0.3 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) YL1 PF05764.8 GAK66666.1 - 0.011 15.4 4.6 0.014 15.0 3.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoplasmin PF03066.10 GAK66666.1 - 0.032 13.7 6.7 0.08 12.4 4.1 1.9 2 0 0 2 2 2 0 Nucleoplasmin Nop14 PF04147.7 GAK66666.1 - 2.6 5.8 8.5 3.6 5.3 5.9 1.3 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 GAK66666.1 - 7.7 6.8 14.8 19 5.5 10.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 GAK66666.1 - 9.1 6.5 11.1 20 5.4 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3292 PF11696.3 GAK66667.1 - 0.00021 19.3 0.5 0.014 13.3 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) Methyltransf_4 PF02390.12 GAK66668.1 - 8.6e-50 168.5 0.0 2.5e-37 127.8 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 GAK66668.1 - 0.00064 20.2 0.1 0.0031 18.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK66668.1 - 0.0041 17.1 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK66668.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 GAK66668.1 - 0.048 13.0 0.0 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 GAK66668.1 - 0.055 13.9 0.0 6.6 7.2 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 GAK66668.1 - 0.059 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAK66668.1 - 0.082 12.4 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NDUFB10 PF10249.4 GAK66669.1 - 0.0033 17.5 0.2 0.0038 17.3 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF4456 PF14644.1 GAK66669.1 - 0.091 11.9 0.2 0.11 11.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) CheZ PF04344.8 GAK66669.1 - 0.11 12.1 0.3 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Prefoldin_2 PF01920.15 GAK66670.1 - 2e-19 69.3 4.2 2.8e-19 68.8 2.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 GAK66670.1 - 0.00043 19.9 1.8 0.00061 19.4 1.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.3 GAK66670.1 - 0.053 13.2 5.2 0.1 12.3 3.5 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 GAK66670.1 - 0.071 13.2 2.3 0.94 9.6 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NTR2 PF15458.1 GAK66670.1 - 0.092 11.9 3.2 0.067 12.4 0.9 1.6 1 1 0 1 1 1 0 Nineteen complex-related protein 2 HrpB7 PF09486.5 GAK66670.1 - 0.11 12.3 4.5 4.9 7.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FliJ PF02050.11 GAK66670.1 - 0.43 10.6 6.5 2.9 7.9 1.1 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein IncA PF04156.9 GAK66670.1 - 2.9 7.4 10.4 21 4.6 0.8 1.9 1 1 0 1 1 1 0 IncA protein CH PF00307.26 GAK66671.1 - 2.8e-68 226.7 0.0 3.1e-19 69.0 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAK66671.1 - 2.4e-09 36.7 0.0 0.31 10.7 0.0 4.4 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 GAK66671.1 - 1.4e-06 28.3 0.6 6.4e-06 26.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAK66671.1 - 0.00015 20.8 0.2 0.037 13.3 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 GAK66671.1 - 0.0024 17.6 0.3 11 6.2 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 GAK66671.1 - 0.091 12.3 0.1 0.34 10.5 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair Abhydrolase_6 PF12697.2 GAK66672.1 - 6.8e-20 71.9 0.0 9.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK66672.1 - 6.2e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK66672.1 - 4.5e-07 29.6 0.1 1.7e-06 27.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 GAK66672.1 - 0.055 12.9 0.2 0.61 9.4 0.1 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 GAK66672.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase TUDOR PF00567.19 GAK66673.1 - 2.9e-06 27.1 0.0 5.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 GAK66673.1 - 4.2e-06 26.0 0.3 4.2e-06 26.0 0.2 3.5 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) DUF3391 PF11871.3 GAK66673.1 - 0.028 14.6 0.5 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PWWP PF00855.12 GAK66673.1 - 0.08 13.1 0.1 0.39 10.9 0.1 2.0 1 1 0 1 1 1 0 PWWP domain PmbA_TldD PF01523.11 GAK66673.1 - 1.2 8.3 4.3 4.9 6.3 0.1 2.1 2 0 0 2 2 2 0 Putative modulator of DNA gyrase Na_H_Exchanger PF00999.16 GAK66674.1 - 6e-66 222.5 47.6 8.3e-66 222.0 33.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Proteasome PF00227.21 GAK66677.1 - 5.2e-50 169.3 0.1 7e-50 168.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAK66677.1 - 2.6e-12 45.8 0.2 4.3e-12 45.1 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RRM_1 PF00076.17 GAK66678.1 - 8.7e-18 63.7 0.0 1.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66678.1 - 1.3e-12 47.4 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 GAK66678.1 - 7.5e-09 35.8 6.9 8.3e-07 29.2 1.3 3.2 2 1 1 3 3 3 2 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 GAK66678.1 - 9.3e-07 28.6 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.1 GAK66679.1 - 1.2e-15 56.9 6.9 3.4e-07 30.2 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAK66679.1 - 1.5e-12 47.0 15.6 3.2e-05 24.0 0.1 4.1 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK66679.1 - 1.7e-12 46.7 11.8 7.3e-05 22.8 0.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAK66679.1 - 8.6e-07 28.9 0.9 0.21 11.7 0.0 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAK66679.1 - 0.0032 17.6 4.4 0.92 9.8 0.0 4.1 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAK66679.1 - 0.022 14.6 3.0 0.6 10.0 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 GAK66679.1 - 0.14 11.9 4.4 0.45 10.3 0.1 2.7 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.1 GAK66679.1 - 0.73 10.1 3.4 1.2 9.5 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 GAK66679.1 - 2.1 8.1 8.4 0.38 10.4 0.7 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Response_reg PF00072.19 GAK66680.1 - 3.9e-18 65.5 0.0 7.9e-10 38.7 0.0 3.5 3 0 0 3 3 3 3 Response regulator receiver domain HATPase_c PF02518.21 GAK66680.1 - 8.8e-18 64.0 0.2 1.8e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAK66680.1 - 1e-16 60.6 0.0 3.4e-16 58.9 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 GAK66680.1 - 1.5e-06 28.4 0.0 0.0005 20.2 0.0 3.5 3 0 0 3 3 3 1 GAF domain Rad60-SLD PF11976.3 GAK66683.1 - 0.018 14.7 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ACT PF01842.20 GAK66683.1 - 0.22 11.0 2.6 1.1 8.8 0.9 2.7 2 0 0 2 2 2 0 ACT domain LSM PF01423.17 GAK66685.1 - 8.2e-17 60.5 0.4 1.3e-16 59.9 0.3 1.3 1 0 0 1 1 1 1 LSM domain DUF3296 PF11726.3 GAK66685.1 - 0.0022 17.5 0.5 0.0027 17.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) tRNA-synt_1c PF00749.16 GAK66686.1 - 8.9e-107 356.3 0.0 1.4e-106 355.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAK66686.1 - 1.9e-34 118.8 0.2 3.8e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 GAK66686.1 - 2.9e-07 30.8 0.9 8.8e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAK66686.1 - 0.0009 19.1 0.6 0.01 15.7 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAK66686.1 - 0.011 15.5 0.1 0.031 14.1 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RNase_H2-Ydr279 PF09468.5 GAK66686.1 - 0.95 8.5 4.6 2.1 7.4 3.2 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) ubiquitin PF00240.18 GAK66687.1 - 0.0014 18.0 0.0 0.0034 16.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 GAK66687.1 - 0.0067 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAK66687.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like VPS28 PF03997.7 GAK66688.1 - 7.5e-58 195.2 3.4 8.7e-58 195.0 2.4 1.0 1 0 0 1 1 1 1 VPS28 protein Bestrophin PF01062.16 GAK66688.1 - 0.18 10.7 1.6 0.2 10.5 0.5 1.5 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel Hus1 PF04005.7 GAK66689.1 - 3.8e-86 288.6 0.5 4.3e-86 288.4 0.4 1.0 1 0 0 1 1 1 1 Hus1-like protein PCNA_N PF00705.13 GAK66689.1 - 0.00092 18.7 0.4 0.0023 17.4 0.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 GAK66689.1 - 0.0026 16.9 0.3 0.017 14.2 0.2 2.1 1 1 0 1 1 1 1 Rad9 PC_rep PF01851.17 GAK66690.1 - 8.1e-44 145.4 15.1 1.7e-08 34.2 0.0 9.6 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 GAK66690.1 - 1.5e-17 63.6 2.5 1.3e-10 41.4 0.0 4.8 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 GAK66690.1 - 1.7e-09 37.8 0.2 0.0014 19.0 0.0 4.8 3 0 0 3 3 3 3 HEAT-like repeat HEAT PF02985.17 GAK66690.1 - 1.8e-07 30.6 0.3 2.4 8.4 0.0 5.0 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 GAK66690.1 - 0.015 15.6 1.6 38 5.1 0.0 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Beta_elim_lyase PF01212.16 GAK66691.1 - 3.4e-67 226.6 0.0 4.7e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pcc1 PF09341.5 GAK66691.1 - 6.8e-17 61.2 0.2 1.5e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 Transcription factor Pcc1 DegT_DnrJ_EryC1 PF01041.12 GAK66691.1 - 0.00069 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 GAK66691.1 - 0.085 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GatB_N PF02934.10 GAK66692.1 - 2.2e-106 354.9 0.0 3.1e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 GAK66692.1 - 5e-26 91.1 0.1 2.5e-25 88.9 0.1 2.0 1 1 0 1 1 1 1 GatB domain zf-LYAR PF08790.6 GAK66693.1 - 1.4e-11 43.8 2.1 2.8e-11 42.9 1.4 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger RRM_6 PF14259.1 GAK66693.1 - 1.2e-07 31.6 0.0 5.8e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK66693.1 - 3.7e-05 23.2 0.0 0.00014 21.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 GAK66693.1 - 0.095 13.0 5.8 0.14 12.5 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cyclin_N PF00134.18 GAK66697.1 - 3.1e-36 123.7 0.3 5.5e-36 122.9 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAK66697.1 - 1.1e-05 25.3 0.1 1.1e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain SR-25 PF10500.4 GAK66697.1 - 0.0069 15.8 18.5 0.0069 15.8 12.8 2.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Aconitase PF00330.15 GAK66698.1 - 3.9e-72 243.2 0.5 3e-46 157.8 0.0 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAK66698.1 - 3.4e-19 69.2 0.4 3.9e-18 65.8 0.0 2.5 2 1 0 2 2 2 1 Aconitase C-terminal domain Svf1 PF08622.5 GAK66699.1 - 2e-99 332.6 0.0 2.5e-99 332.3 0.0 1.1 1 0 0 1 1 1 1 Svf1-like PQQ PF01011.16 GAK66699.1 - 0.042 13.3 0.2 0.43 10.1 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat TFIIB PF00382.14 GAK66700.1 - 1.5e-37 127.2 0.7 2.7e-22 78.3 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 GAK66700.1 - 6.1e-13 47.8 1.4 9.7e-13 47.2 1.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 GAK66700.1 - 0.00059 19.7 0.0 0.048 13.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain PG_binding_1 PF01471.13 GAK66700.1 - 0.058 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Cyclin_N PF00134.18 GAK66700.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Nup84_Nup100 PF04121.8 GAK66701.1 - 3.2e-107 358.9 0.0 3.2e-54 183.8 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 C2 PF00168.25 GAK66702.1 - 2.9e-18 65.4 0.0 6.9e-13 48.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain Ribul_P_3_epim PF00834.14 GAK66704.1 - 5.7e-64 214.9 0.1 8.2e-64 214.4 0.1 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 GAK66704.1 - 0.032 14.2 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 Predicted Peptidoglycan domain QRPTase_C PF01729.14 GAK66704.1 - 0.033 13.7 0.0 0.082 12.4 0.0 1.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain F-box-like PF12937.2 GAK66705.1 - 0.002 17.8 1.3 0.004 16.8 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK66705.1 - 0.13 11.9 0.2 0.41 10.3 0.2 1.9 1 1 0 1 1 1 0 F-box domain Mago-bind PF09282.5 GAK66706.1 - 2e-13 49.6 2.2 9.1e-13 47.5 1.5 2.2 1 0 0 1 1 1 1 Mago binding Dicty_REP PF05086.7 GAK66706.1 - 0.84 7.3 4.0 1 6.9 2.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2365 PF10157.4 GAK66706.1 - 4.9 7.0 5.6 11 5.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2365) MAPEG PF01124.13 GAK66707.1 - 8.8e-14 51.2 1.7 1.4e-13 50.5 1.2 1.4 1 0 0 1 1 1 1 MAPEG family GST_N PF02798.15 GAK66708.1 - 7.9e-16 57.9 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAK66708.1 - 1.3e-10 41.3 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAK66708.1 - 3e-08 33.4 0.2 4.8e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAK66708.1 - 4e-08 33.1 0.0 7.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAK66708.1 - 2.1e-07 30.8 0.0 3.4e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAK66708.1 - 6.4e-05 23.3 0.0 9.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain COX5B PF01215.14 GAK66710.1 - 2.5e-32 111.4 0.0 3.9e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb AMP-binding PF00501.23 GAK66711.1 - 3e-73 246.5 0.0 6.1e-73 245.5 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK66711.1 - 1.1e-08 35.8 0.1 3.2e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 GAK66713.1 - 5.2e-24 84.5 0.0 1.1e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK66713.1 - 2.4e-06 27.3 6.0 4.2e-06 26.5 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2380 PF09533.5 GAK66713.1 - 0.16 11.3 1.9 0.37 10.1 1.3 1.5 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Kelch_4 PF13418.1 GAK66714.1 - 1.3e-23 82.4 9.4 3.3e-06 26.7 0.0 6.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 GAK66714.1 - 2.9e-10 39.9 26.7 0.00014 21.9 0.3 7.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 GAK66714.1 - 6.3e-09 35.5 9.2 0.00028 20.7 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 GAK66714.1 - 9.5e-09 35.0 8.7 0.0024 17.9 0.0 5.3 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 GAK66714.1 - 4.3e-08 32.6 1.3 0.044 13.5 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 GAK66714.1 - 0.0061 16.0 0.0 1.7 8.2 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Pkinase PF00069.20 GAK66715.1 - 2.9e-49 167.5 0.0 4.3e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66715.1 - 4.3e-46 157.0 0.0 6e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 GAK66715.1 - 6.3e-07 29.0 2.1 1.3e-06 28.0 1.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 GAK66715.1 - 0.0078 15.9 0.1 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAK66715.1 - 0.018 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_3 PF07649.7 GAK66715.1 - 0.064 13.2 1.3 0.15 12.1 0.9 1.6 1 0 0 1 1 1 0 C1-like domain zf-HC5HC2H_2 PF13832.1 GAK66715.1 - 0.11 12.5 0.5 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_2 PF03107.11 GAK66715.1 - 0.18 11.9 2.9 0.32 11.1 2.0 1.4 1 0 0 1 1 1 0 C1 domain PHD PF00628.24 GAK66715.1 - 0.18 11.4 4.2 0.36 10.5 2.9 1.5 1 0 0 1 1 1 0 PHD-finger Ebp2 PF05890.7 GAK66716.1 - 8.2e-90 300.7 17.0 8.2e-90 300.7 11.8 2.1 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 ABC2_membrane PF01061.19 GAK66718.1 - 1.5e-34 119.0 18.4 1.5e-34 119.0 12.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 GAK66718.1 - 4.1e-23 82.1 0.0 7.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAK66718.1 - 2e-05 24.7 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAK66718.1 - 0.0047 16.9 0.1 0.0079 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 GAK66718.1 - 0.0099 15.0 0.4 0.022 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 GAK66718.1 - 0.044 12.8 28.0 0.12 11.3 19.4 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_25 PF13481.1 GAK66718.1 - 0.048 13.0 1.1 0.19 11.1 0.8 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAK66718.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAK66718.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAK66718.1 - 0.18 12.6 0.0 0.35 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAK66718.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAK66718.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Dynamin family Miro PF08477.8 GAK66718.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 GAK66718.1 - 0.22 11.2 0.1 0.41 10.3 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Med15_fungi PF05397.7 GAK66720.1 - 1.2e-32 112.2 1.7 1.2e-32 112.2 1.2 5.4 6 1 1 7 7 7 1 Mediator complex subunit 15 ARID PF01388.16 GAK66720.1 - 7.4e-18 64.1 2.6 1.4e-17 63.3 0.0 2.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PhoD PF09423.5 GAK66721.1 - 0.00012 20.7 0.1 0.00023 19.8 0.1 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase P3A PF08727.6 GAK66721.1 - 0.0058 15.9 6.3 0.11 11.8 0.0 3.7 4 0 0 4 4 4 2 Poliovirus 3A protein like ATP12 PF07542.6 GAK66721.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP12 chaperone protein Glyco_hydro_45 PF02015.11 GAK66723.1 - 7.2e-49 166.5 5.7 1.1e-48 165.9 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 PT PF04886.7 GAK66723.1 - 0.59 9.5 34.6 0.025 13.8 8.2 2.9 2 1 1 3 3 3 0 PT repeat DUF4106 PF13388.1 GAK66723.1 - 3.2 6.6 21.1 0.53 9.1 11.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) C2 PF00168.25 GAK66724.1 - 3.3e-48 161.4 0.2 4.6e-12 45.6 0.0 4.5 4 0 0 4 4 4 4 C2 domain NT-C2 PF10358.4 GAK66724.1 - 0.023 14.2 0.0 36 3.8 0.0 4.3 4 1 1 5 5 5 0 N-terminal C2 in EEIG1 and EHBP1 proteins Ubiq_cyt_C_chap PF03981.7 GAK66725.1 - 1e-27 96.7 0.1 1.3e-25 89.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone PP2C PF00481.16 GAK66726.1 - 1.9e-36 125.7 0.0 1.1e-32 113.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C WAC_Acf1_DNA_bd PF10537.4 GAK66727.1 - 1.1e-37 128.2 0.0 3.8e-37 126.5 0.0 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 GAK66727.1 - 2.8e-12 46.1 0.1 4.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 GAK66727.1 - 4.1e-05 23.3 0.0 0.00016 21.4 0.0 2.0 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 GAK66727.1 - 7.5e-05 22.4 0.0 0.00028 20.5 0.0 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 GAK66727.1 - 0.00093 19.0 0.1 0.0027 17.5 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF2985 PF11204.3 GAK66728.1 - 6.4e-31 105.9 1.9 1.1e-30 105.2 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Neur_chan_memb PF02932.11 GAK66728.1 - 0.3 10.9 9.3 1.1 9.0 0.1 3.4 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Molybdopterin PF00384.17 GAK66729.1 - 1e-76 258.4 0.0 4.5e-76 256.3 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 GAK66729.1 - 3.4e-18 64.5 0.0 1e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 GAK66729.1 - 4.5e-17 61.6 0.1 1.2e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 GAK66729.1 - 5e-17 61.7 0.1 1.4e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 GAK66729.1 - 7.9e-09 35.1 0.5 2.2e-08 33.7 0.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 GAK66729.1 - 0.00077 19.2 0.3 0.12 12.1 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Aha1_N PF09229.6 GAK66730.1 - 1.1e-31 109.4 0.0 1.6e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 GAK66730.1 - 1.7e-15 57.1 0.0 1.6e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Med3 PF11593.3 GAK66730.1 - 6 6.0 11.4 9.5 5.3 7.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal bZIP_2 PF07716.10 GAK66731.1 - 0.0057 16.4 6.3 0.012 15.4 4.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Nefa_Nip30_N PF10187.4 GAK66732.1 - 2e-20 72.8 7.9 2e-20 72.8 5.5 1.9 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Plasmodium_Vir PF05795.6 GAK66732.1 - 0.15 11.2 4.2 0.19 10.9 2.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Arm PF00514.18 GAK66733.1 - 6.1e-97 314.5 5.3 6e-13 48.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAK66733.1 - 8.5e-31 106.0 2.4 3.1e-08 33.7 0.0 6.3 1 1 6 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 GAK66733.1 - 2.8e-22 78.5 0.6 2.8e-08 34.0 0.0 6.1 5 2 1 6 6 5 3 HEAT-like repeat IBB PF01749.15 GAK66733.1 - 3.2e-20 72.0 8.3 5.5e-20 71.3 5.8 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 GAK66733.1 - 8.9e-19 65.8 1.2 2.7e-05 23.8 0.0 7.1 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.15 GAK66733.1 - 2.1e-07 29.6 0.0 4.4e-05 22.0 0.0 2.8 1 1 1 2 2 2 1 Adaptin N terminal region Arm_2 PF04826.8 GAK66733.1 - 6.2e-06 25.5 0.0 0.034 13.2 0.0 3.6 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.9 GAK66733.1 - 9.7e-05 21.6 0.0 1.2 8.1 0.0 3.3 1 1 1 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 GAK66733.1 - 0.00026 20.8 0.0 0.23 11.4 0.0 4.2 3 2 1 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.1 GAK66733.1 - 0.00072 19.4 3.5 0.29 11.0 0.0 4.2 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 GAK66733.1 - 0.0011 19.2 0.4 1.1 9.8 0.1 4.4 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 GAK66733.1 - 0.0093 14.2 0.0 1.9 6.6 0.0 2.8 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit DUF330 PF03886.8 GAK66733.1 - 0.013 14.8 0.1 0.081 12.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF330) Mo25 PF08569.6 GAK66733.1 - 0.041 12.9 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 Mo25-like GTP_cyclohydro2 PF00925.15 GAK66734.1 - 1.9e-65 219.2 0.1 1.2e-59 200.3 0.1 2.5 2 0 0 2 2 2 2 GTP cyclohydrolase II Metallophos PF00149.23 GAK66735.1 - 3.1e-41 140.9 0.2 4e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L7Ae PF01248.21 GAK66737.1 - 1.9e-23 81.7 0.0 2.2e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.23 GAK66737.1 - 0.025 14.5 0.0 0.054 13.5 0.0 1.5 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L37e PF01907.14 GAK66738.1 - 1.2e-24 85.8 11.7 1.2e-24 85.8 8.1 1.7 2 1 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 GAK66738.1 - 0.00073 19.2 2.1 0.0011 18.7 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 GAK66738.1 - 0.015 14.9 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 SelR domain HypA PF01155.14 GAK66738.1 - 0.1 12.2 1.0 0.14 11.8 0.7 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF1462 PF07315.6 GAK66738.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) zf-ribbon_3 PF13248.1 GAK66738.1 - 0.5 9.6 3.5 2.3 7.5 2.6 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 GAK66738.1 - 1.7 8.3 4.7 2.8 7.6 3.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Leo1 PF04004.8 GAK66739.1 - 1.6e-52 177.6 0.1 5.7e-52 175.8 0.0 2.0 1 0 0 1 1 1 1 Leo1-like protein SPT6_acidic PF14632.1 GAK66739.1 - 0.0035 17.4 16.0 0.0035 17.4 11.1 6.4 6 1 0 6 6 6 2 Acidic N-terminal SPT6 Mgm101p PF06420.7 GAK66740.1 - 9.9e-84 278.8 0.0 1.3e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Acyl-CoA_dh_1 PF00441.19 GAK66742.1 - 3.9e-44 150.3 2.5 6.9e-44 149.5 1.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAK66742.1 - 3.5e-36 124.2 0.0 6.8e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAK66742.1 - 1e-20 72.9 0.1 2.3e-20 71.8 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAK66742.1 - 4e-20 72.4 0.3 7.3e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 GAK66742.1 - 0.024 14.9 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Yae1_N PF09811.4 GAK66743.1 - 2.4e-10 39.7 6.5 4.2e-10 38.9 4.5 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.17 GAK66744.1 - 1.9e-12 46.6 0.7 2e-08 33.7 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66744.1 - 6.3e-06 25.9 0.0 0.001 18.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66744.1 - 1.1e-05 25.3 0.5 0.00062 19.6 0.0 3.1 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP PF03399.11 GAK66745.1 - 1.3e-34 119.5 0.0 1.8e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 GAK66745.1 - 2.5e-28 98.6 0.0 7.7e-28 97.0 0.0 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 NAM PF02365.10 GAK66745.1 - 0.083 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 No apical meristem (NAM) protein CLTH PF10607.4 GAK66745.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain NUDIX PF00293.23 GAK66746.1 - 1.1e-25 89.8 0.0 1.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L6 PF00347.18 GAK66747.1 - 3.5e-21 75.4 0.8 4.5e-09 36.6 0.1 3.2 3 0 0 3 3 3 3 Ribosomal protein L6 SR-25 PF10500.4 GAK66747.1 - 2.2 7.7 10.0 4.5 6.6 6.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PC-Esterase PF13839.1 GAK66749.1 - 0.0014 18.4 0.0 0.0046 16.7 0.0 1.8 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MFS_1 PF07690.11 GAK66750.1 - 5.1e-09 35.3 23.8 1.1e-08 34.2 16.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAK66750.1 - 0.0004 19.9 3.6 0.0004 19.9 2.5 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Cation_ATPase_C PF00689.16 GAK66750.1 - 0.41 10.1 12.9 0.29 10.6 0.3 3.5 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus Aminotran_1_2 PF00155.16 GAK66751.1 - 7.3e-56 189.6 0.0 9.6e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAK66751.1 - 0.00026 20.2 0.0 0.00044 19.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 GAK66751.1 - 0.011 14.2 0.0 0.062 11.8 0.0 1.9 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.15 GAK66751.1 - 0.015 13.5 0.0 0.026 12.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 GAK66751.1 - 0.078 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III zf-DHHC PF01529.15 GAK66752.1 - 8.8e-29 100.1 0.0 1.4e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase CobS_N PF12556.3 GAK66752.1 - 0.092 12.1 0.7 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Cobaltochelatase CobS subunit N terminal DUF2124 PF09897.4 GAK66752.1 - 0.26 10.9 0.0 0.52 9.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Formyl_trans_N PF00551.14 GAK66753.1 - 1.7e-19 70.0 0.0 2.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 GAK66753.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain AIG2 PF06094.7 GAK66754.1 - 4.8e-15 55.8 0.1 1.3e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 AIG2-like family Acyltransferase PF01553.16 GAK66754.1 - 1.7e-13 50.1 0.0 5.1e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Aminotran_5 PF00266.14 GAK66755.1 - 9.6e-10 37.7 0.0 2.4e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DUF3337 PF11816.3 GAK66756.1 - 0.015 14.7 0.7 0.022 14.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Hex_IIIa PF02455.11 GAK66756.1 - 0.33 9.5 8.4 0.032 12.9 1.5 2.0 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) CDC45 PF02724.9 GAK66756.1 - 2.7 5.9 6.8 3.2 5.6 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_2b PF00587.20 GAK66757.1 - 2.3e-43 147.7 0.0 4.5e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAK66757.1 - 3.9e-20 71.5 0.1 8.5e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 GAK66757.1 - 4.7e-14 51.9 0.0 5.2e-12 45.4 0.0 2.5 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 GAK66757.1 - 3.6e-10 39.5 0.0 6.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain SPX PF03105.14 GAK66758.1 - 0.039 13.7 0.2 0.048 13.4 0.2 1.2 1 0 0 1 1 1 0 SPX domain CENP-F_N PF10481.4 GAK66758.1 - 0.064 12.6 0.8 0.081 12.2 0.5 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain DUF724 PF05266.9 GAK66758.1 - 0.065 12.8 0.6 0.091 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF605 PF04652.11 GAK66758.1 - 0.64 9.3 19.4 0.76 9.1 13.4 1.2 1 0 0 1 1 1 0 Vta1 like PTPA PF03095.10 GAK66759.1 - 1.4e-94 316.6 0.0 2.9e-94 315.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SAC3_GANP PF03399.11 GAK66760.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family AhpC-TSA PF00578.16 GAK66761.1 - 7.6e-22 77.3 0.0 1e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAK66761.1 - 4.5e-11 42.4 0.0 6.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 GAK66761.1 - 0.015 15.1 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ank_2 PF12796.2 GAK66762.1 - 1.4e-28 99.0 1.5 1.4e-19 70.2 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAK66762.1 - 4.3e-17 60.9 4.4 5.9e-08 32.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAK66762.1 - 7e-16 58.2 0.6 1.1e-06 28.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK66762.1 - 7.1e-15 53.6 1.1 7.2e-05 22.6 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 GAK66762.1 - 8.1e-12 44.9 5.1 1.5e-06 28.2 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF4316 PF14195.1 GAK66763.1 - 0.08 13.0 0.2 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Suf PF05843.9 GAK66763.1 - 0.28 10.8 2.4 0.28 10.8 1.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 GAK66763.1 - 7.5 5.2 9.4 9.1 4.9 6.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.20 GAK66764.1 - 5.4e-52 176.5 0.0 7.3e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66764.1 - 3e-41 141.2 0.0 4.6e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK66764.1 - 0.0012 17.8 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK66764.1 - 0.017 14.8 0.9 0.032 13.9 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF2305 PF10230.4 GAK66765.1 - 1.1e-43 149.5 0.0 2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Chromo PF00385.19 GAK66765.1 - 2.8e-11 42.8 0.9 6.2e-11 41.8 0.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Abhydrolase_6 PF12697.2 GAK66765.1 - 4.5e-11 43.0 4.1 1e-10 41.9 2.8 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK66765.1 - 2.1e-07 30.7 0.4 5.3e-07 29.5 0.3 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chromo_shadow PF01393.14 GAK66765.1 - 0.00011 22.0 0.1 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain Lipase_3 PF01764.20 GAK66765.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 GAK66765.1 - 0.1 12.1 0.1 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Kei1 PF08552.6 GAK66766.1 - 2.1e-50 171.0 3.2 3.7e-50 170.2 2.2 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 KOW PF00467.24 GAK66766.1 - 2.2e-06 27.1 0.6 5e-06 26.0 0.4 1.6 1 0 0 1 1 1 1 KOW motif DUF4199 PF13858.1 GAK66766.1 - 0.24 11.3 6.9 0.4 10.5 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Cid2 PF09774.4 GAK66768.1 - 0.16 12.0 1.9 0.22 11.6 1.3 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Per1 PF04080.8 GAK66769.1 - 6e-109 363.5 0.3 8.3e-109 363.1 0.2 1.2 1 0 0 1 1 1 1 Per1-like DUF802 PF05650.6 GAK66769.1 - 0.022 14.8 1.1 0.047 13.8 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Methyltrn_RNA_3 PF02598.12 GAK66770.1 - 1.8e-79 267.1 0.0 2.3e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase RRM_6 PF14259.1 GAK66771.1 - 3e-11 43.1 0.0 4.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK66771.1 - 3.9e-11 42.4 0.1 1.3e-10 40.7 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66771.1 - 1.8e-06 27.7 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 GAK66771.1 - 5 4.9 9.2 8.1 4.2 6.4 1.3 1 0 0 1 1 1 0 Nop14-like family D123 PF07065.9 GAK66772.1 - 8.6e-76 254.8 0.0 1e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 GAK66772.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) EF-1_beta_acid PF10587.4 GAK66772.1 - 2.4 8.4 8.9 4.9 7.3 6.1 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region HLH PF00010.21 GAK66773.1 - 0.00028 20.5 0.1 0.00059 19.4 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.1 GAK66773.1 - 0.003 17.9 4.8 0.0097 16.3 3.4 1.9 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 Neur_chan_memb PF02932.11 GAK66773.1 - 1.8 8.3 5.2 3.6 7.4 0.5 2.7 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 GAK66774.1 - 1e-61 208.3 0.0 1.3e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66774.1 - 1.9e-35 122.2 0.0 3.3e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK66774.1 - 3.5e-09 36.0 0.0 6.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK66774.1 - 0.033 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAK66774.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 GAK66774.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Snf7 PF03357.16 GAK66775.1 - 4.2e-41 140.1 20.3 9.3e-41 139.0 13.3 1.8 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 GAK66775.1 - 0.062 11.1 1.5 0.075 10.8 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 GAK66775.1 - 0.089 12.1 3.5 0.13 11.7 2.4 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF1043 PF06295.7 GAK66775.1 - 0.22 11.1 3.6 0.38 10.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Pox_A_type_inc PF04508.7 GAK66775.1 - 0.35 10.7 4.7 1 9.3 3.3 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TPR_MLP1_2 PF07926.7 GAK66775.1 - 0.51 10.0 10.4 0.95 9.2 7.2 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2570 PF10828.3 GAK66775.1 - 1.4 8.5 6.1 0.3 10.7 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) COG2 PF06148.6 GAK66775.1 - 1.4 8.7 8.2 0.46 10.3 3.0 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PspA_IM30 PF04012.7 GAK66775.1 - 2.8 7.2 21.3 0.039 13.3 4.6 2.1 1 1 1 2 2 2 0 PspA/IM30 family YlqD PF11068.3 GAK66775.1 - 5.8 6.9 14.6 11 6.1 8.9 2.0 1 1 1 2 2 2 0 YlqD protein CLN3 PF02487.12 GAK66776.1 - 1.9e-62 211.3 13.6 2.4e-52 178.0 2.5 4.7 2 1 1 3 3 3 3 CLN3 protein Clp1 PF06807.9 GAK66777.1 - 5.6e-08 32.7 0.0 5.6e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 GAK66777.1 - 0.0027 17.3 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 GAK66777.1 - 0.0044 17.0 0.6 0.017 15.0 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain W2 PF02020.13 GAK66778.1 - 3.8e-17 62.0 1.1 3.8e-17 62.0 0.8 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 GAK66778.1 - 4.3e-13 48.1 5.9 1.3e-06 27.6 0.7 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 GAK66778.1 - 5.8e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 GAK66778.1 - 0.00053 20.0 0.0 0.00098 19.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 GAK66778.1 - 0.024 14.1 9.7 0.19 11.3 4.6 3.5 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 GAK66778.1 - 0.19 10.2 0.6 0.34 9.4 0.4 1.4 1 0 0 1 1 1 0 L-fucokinase RNA_pol_Rpc4 PF05132.9 GAK66779.1 - 3.9e-28 98.0 0.7 3.9e-28 98.0 0.5 3.9 4 1 0 4 4 4 2 RNA polymerase III RPC4 PGK PF00162.14 GAK66780.1 - 1e-147 491.7 0.8 1.2e-147 491.5 0.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Arginosuc_synth PF00764.14 GAK66781.1 - 1.3e-159 531.4 0.0 1.5e-159 531.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 GAK66781.1 - 0.00027 20.2 0.0 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 GAK66781.1 - 0.0031 17.0 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 GAK66781.1 - 0.021 13.3 0.0 0.057 11.9 0.0 1.6 1 1 1 2 2 2 0 tRNA methyl transferase Iso_dh PF00180.15 GAK66782.1 - 4.6e-91 305.3 0.0 6e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2 PF00096.21 GAK66784.1 - 8.2e-10 38.4 7.5 4.4e-05 23.5 0.3 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK66784.1 - 6.9e-09 35.5 2.5 2.1e-06 27.7 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAK66784.1 - 8.2e-09 35.1 2.4 0.00045 20.3 0.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAK66784.1 - 2.4e-05 24.3 2.3 0.13 12.4 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 GAK66784.1 - 0.0023 17.6 0.6 0.93 9.3 0.0 2.5 2 0 0 2 2 2 2 BED zinc finger PyrI_C PF02748.10 GAK66784.1 - 0.21 11.0 0.0 6.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.2 GAK66784.1 - 0.22 11.6 1.0 3.8 7.6 0.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) APC_CDC26 PF10471.4 GAK66784.1 - 0.83 10.4 11.1 3.4 8.4 4.8 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 zf-met PF12874.2 GAK66784.1 - 0.88 9.8 7.6 0.76 10.0 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAK66784.1 - 6.2 6.8 8.6 6.3 6.8 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger AAA_5 PF07728.9 GAK66788.1 - 2.8e-122 402.9 0.0 1.4e-21 76.6 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAK66788.1 - 8e-26 90.1 0.0 1.4e-06 27.9 0.0 8.1 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 GAK66788.1 - 8.3e-26 90.7 0.0 0.0047 17.1 0.0 7.4 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAK66788.1 - 5.5e-23 81.5 3.3 0.05 13.7 0.0 9.4 8 1 0 8 8 7 6 AAA domain AAA_17 PF13207.1 GAK66788.1 - 8.6e-22 78.2 0.0 0.19 12.5 0.0 7.5 6 0 0 6 6 6 6 AAA domain AAA_33 PF13671.1 GAK66788.1 - 1.8e-20 73.2 3.3 0.049 13.5 0.0 8.6 7 1 0 7 7 6 5 AAA domain AAA_18 PF13238.1 GAK66788.1 - 5e-17 62.4 6.9 0.1 12.8 0.0 7.8 7 0 0 7 7 6 4 AAA domain AAA_19 PF13245.1 GAK66788.1 - 2.2e-16 59.3 10.9 0.0029 17.3 0.2 7.4 6 0 0 6 6 6 3 Part of AAA domain Zeta_toxin PF06414.7 GAK66788.1 - 2.5e-16 59.4 2.0 0.083 11.9 0.0 7.7 7 1 0 7 7 7 5 Zeta toxin Sigma54_activ_2 PF14532.1 GAK66788.1 - 5.7e-16 58.8 2.3 0.0054 16.7 0.1 7.5 7 0 0 7 7 6 3 Sigma-54 interaction domain ABC_tran PF00005.22 GAK66788.1 - 8.5e-16 58.4 0.2 0.14 12.4 0.0 6.9 6 0 0 6 6 6 4 ABC transporter AAA_16 PF13191.1 GAK66788.1 - 9.3e-14 51.8 68.4 0.00017 21.6 1.8 13.6 13 2 1 14 14 11 5 AAA ATPase domain AAA_14 PF13173.1 GAK66788.1 - 3.1e-13 49.7 0.0 0.00083 19.2 0.0 6.7 8 0 0 8 8 6 2 AAA domain T2SE PF00437.15 GAK66788.1 - 4.7e-13 48.6 2.8 0.14 11.0 0.0 6.4 6 0 0 6 6 6 4 Type II/IV secretion system protein Sigma54_activat PF00158.21 GAK66788.1 - 4.4e-12 45.8 0.0 0.061 12.7 0.0 6.2 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_28 PF13521.1 GAK66788.1 - 6.2e-12 45.7 8.6 0.064 13.2 0.0 7.4 6 0 0 6 6 6 3 AAA domain AAA_29 PF13555.1 GAK66788.1 - 6.9e-12 44.7 3.4 0.41 10.1 0.1 6.2 6 0 0 6 6 6 3 P-loop containing region of AAA domain UPF0079 PF02367.12 GAK66788.1 - 3.3e-11 42.8 2.6 0.13 11.9 0.0 6.4 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 GAK66788.1 - 5.4e-10 38.9 6.0 0.18 11.2 0.1 6.9 7 0 0 7 7 7 3 AAA domain RNA_helicase PF00910.17 GAK66788.1 - 5.8e-10 39.3 0.5 2.2 8.5 0.0 6.6 6 0 0 6 6 6 1 RNA helicase MobB PF03205.9 GAK66788.1 - 6.3e-10 38.9 0.6 2.2 8.0 0.0 6.2 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 GAK66788.1 - 1.1e-09 37.7 4.5 0.18 10.9 0.1 7.1 8 0 0 8 8 7 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 GAK66788.1 - 2.3e-09 37.1 4.3 0.11 12.1 0.0 6.4 5 0 0 5 5 5 1 NACHT domain Miro PF08477.8 GAK66788.1 - 5.9e-08 33.2 0.6 13 6.3 0.0 6.6 6 0 0 6 6 6 0 Miro-like protein DUF258 PF03193.11 GAK66788.1 - 1.5e-07 30.7 2.4 3 7.0 0.0 5.7 6 0 0 6 6 5 1 Protein of unknown function, DUF258 DUF815 PF05673.8 GAK66788.1 - 7.1e-07 28.3 0.5 0.17 10.8 0.0 5.1 6 0 0 6 6 6 1 Protein of unknown function (DUF815) PduV-EutP PF10662.4 GAK66788.1 - 8.9e-07 28.4 1.6 3.8 6.9 0.1 5.4 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 GAK66788.1 - 2.4e-06 27.1 2.8 3.1 7.2 0.1 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 GAK66788.1 - 1.5e-05 24.8 0.1 0.5 10.3 0.0 5.4 6 0 0 6 6 5 1 50S ribosome-binding GTPase SRP54 PF00448.17 GAK66788.1 - 5.2e-05 22.7 3.3 1.4 8.2 0.1 4.9 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain ResIII PF04851.10 GAK66788.1 - 8.8e-05 22.4 0.0 9.4 6.0 0.0 4.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_21 PF13304.1 GAK66788.1 - 0.00067 19.7 0.0 2.4 8.0 0.0 4.8 6 0 0 6 6 5 1 AAA domain Rad17 PF03215.10 GAK66788.1 - 0.0012 17.6 1.2 12 4.4 0.0 4.5 5 0 0 5 5 5 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 GAK66788.1 - 0.0017 18.1 0.0 4.8 6.7 0.0 4.8 6 0 0 6 6 4 0 Archaeal ATPase ATP_bind_1 PF03029.12 GAK66788.1 - 0.0058 16.1 5.9 25 4.2 0.0 5.2 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 GAK66788.1 - 0.0075 16.0 6.7 1.8 8.2 0.0 5.1 6 0 0 6 6 4 1 NTPase Dynamin_N PF00350.18 GAK66788.1 - 0.024 14.4 6.5 7.8 6.2 0.1 6.2 6 0 0 6 6 6 0 Dynamin family PhoH PF02562.11 GAK66788.1 - 0.038 13.2 2.0 30 3.7 0.0 4.3 4 0 0 4 4 4 0 PhoH-like protein KTI12 PF08433.5 GAK66788.1 - 0.076 12.2 4.7 0.17 11.0 0.0 4.0 6 0 0 6 6 4 0 Chromatin associated protein KTI12 AAA_6 PF12774.2 GAK66788.1 - 0.082 12.4 0.0 38 3.6 0.0 4.6 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 TIP49 PF06068.8 GAK66788.1 - 0.13 10.9 3.4 3 6.4 0.1 4.0 5 0 0 5 5 5 0 TIP49 C-terminus PRK PF00485.13 GAK66788.1 - 0.15 11.5 1.4 59 3.1 0.0 4.1 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family Gtr1_RagA PF04670.7 GAK66788.1 - 0.3 10.1 1.4 13 4.8 0.0 3.7 4 0 0 4 4 4 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.2 GAK66788.1 - 0.5 9.4 0.0 12 4.8 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region D3 Adeno_IVa2 PF02456.10 GAK66788.1 - 1.8 7.1 0.0 19 3.7 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein KaiC PF06745.8 GAK66788.1 - 2.1 7.3 0.6 73 2.3 0.0 3.3 4 0 0 4 4 3 0 KaiC AAA_PrkA PF08298.6 GAK66788.1 - 2.4 6.7 0.7 1.2e+02 1.1 0.0 3.2 3 0 0 3 3 3 0 PrkA AAA domain PPV_E1_C PF00519.12 GAK66788.1 - 7.9 4.9 0.0 22 3.5 0.0 1.7 2 0 0 2 2 1 0 Papillomavirus helicase TFIIS_C PF01096.13 GAK66789.1 - 5.1e-17 61.2 6.2 3.3e-16 58.6 0.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAK66789.1 - 3.1e-07 29.9 8.2 0.00015 21.3 0.3 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.7 GAK66789.1 - 0.00038 19.7 9.2 0.064 12.5 0.5 2.8 2 1 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 GAK66789.1 - 0.0004 19.4 17.0 0.035 13.2 2.9 3.7 3 1 0 3 3 3 2 zinc-ribbon domain DZR PF12773.2 GAK66789.1 - 0.00046 19.9 9.4 0.061 13.1 0.4 3.0 1 1 0 2 2 2 2 Double zinc ribbon Lar_restr_allev PF14354.1 GAK66789.1 - 0.00086 19.5 10.2 0.0041 17.3 0.5 3.0 2 1 0 2 2 2 1 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 GAK66789.1 - 0.002 17.7 5.7 0.086 12.5 0.1 2.7 2 1 0 2 2 2 1 Putative transposase DNA-binding domain Terminase_GpA PF05876.7 GAK66789.1 - 0.0096 14.3 0.5 0.023 13.0 0.2 1.7 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) IBR PF01485.16 GAK66789.1 - 0.016 15.0 4.1 1.9 8.4 0.0 2.6 2 1 0 2 2 2 0 IBR domain zf-ISL3 PF14690.1 GAK66789.1 - 0.023 14.7 7.8 11 6.1 0.0 3.8 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-TFIIB PF13453.1 GAK66789.1 - 0.026 13.6 1.3 0.026 13.6 0.9 2.8 3 1 0 3 3 2 0 Transcription factor zinc-finger zinc_ribbon_2 PF13240.1 GAK66789.1 - 0.045 13.2 20.1 0.47 10.0 2.1 3.6 2 2 1 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 GAK66789.1 - 0.047 13.9 0.2 0.047 13.9 0.1 3.6 4 0 0 4 4 3 0 Zinc-finger double domain DUF2387 PF09526.5 GAK66789.1 - 0.053 13.4 4.2 1.9 8.4 0.2 2.7 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Prok-RING_1 PF14446.1 GAK66789.1 - 0.093 12.4 9.6 0.89 9.3 0.8 3.4 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 CpXC PF14353.1 GAK66789.1 - 0.11 12.4 5.4 23 4.9 0.0 3.7 3 1 0 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.5 GAK66789.1 - 0.15 12.0 15.9 7.4 6.6 0.6 4.2 2 2 1 4 4 4 0 Zinc ribbon domain Nudix_N_2 PF14803.1 GAK66789.1 - 0.18 11.4 7.6 1.8 8.3 0.0 3.9 4 0 0 4 4 4 0 Nudix N-terminal DUF164 PF02591.10 GAK66789.1 - 0.2 11.4 6.0 2.3 8.1 0.0 3.3 3 1 0 3 3 3 0 Putative zinc ribbon domain Zn_ribbon_recom PF13408.1 GAK66789.1 - 0.22 11.8 6.7 5 7.4 0.1 3.5 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 GAK66789.1 - 0.25 10.9 13.0 15 5.1 0.1 3.9 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-LSD1 PF06943.7 GAK66789.1 - 0.25 11.0 0.2 0.25 11.0 0.2 2.1 2 0 0 2 2 1 0 LSD1 zinc finger Baculo_LEF5_C PF11792.3 GAK66789.1 - 0.29 10.5 0.1 0.29 10.5 0.1 2.1 3 1 0 3 3 1 0 Baculoviridae late expression factor 5 C-terminal domain PolC_DP2 PF03833.8 GAK66789.1 - 0.3 8.7 1.9 0.62 7.6 0.3 1.8 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 Nop10p PF04135.7 GAK66789.1 - 0.36 10.5 3.5 1.6 8.5 0.0 3.3 4 0 0 4 4 4 0 Nucleolar RNA-binding protein, Nop10p family zinc-ribbons_6 PF07191.7 GAK66789.1 - 0.54 10.0 5.5 6.9 6.5 0.1 2.9 2 1 0 3 3 3 0 zinc-ribbons Ribosomal_S27e PF01667.12 GAK66789.1 - 0.58 9.7 7.5 2.9 7.4 0.0 3.7 3 1 1 4 4 4 0 Ribosomal protein S27 zf-DNA_Pol PF08996.5 GAK66789.1 - 0.79 9.0 4.4 0.17 11.2 0.2 1.9 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.2 GAK66789.1 - 0.87 9.4 11.7 4.4 7.1 1.7 3.6 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 GAK66789.1 - 1.2 8.8 14.0 6.5 6.4 0.4 4.1 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAK66789.1 - 1.4 8.7 13.6 8.4 6.1 0.4 4.1 3 1 1 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 GAK66789.1 - 1.5 8.4 5.0 19 4.8 0.0 3.5 4 0 0 4 4 4 0 InsA N-terminal domain zf-C2H2 PF00096.21 GAK66789.1 - 1.7 9.1 9.9 1 9.8 0.9 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LITAF-like PF10601.4 GAK66789.1 - 1.7 8.5 5.2 37 4.2 0.0 3.6 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Rpr2 PF04032.11 GAK66789.1 - 2 8.3 4.4 77 3.2 3.0 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain UPF0547 PF10571.4 GAK66789.1 - 2.3 8.0 19.5 0.49 10.1 0.2 3.8 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF3797 PF12677.2 GAK66789.1 - 2.4 7.8 14.0 4.1 7.1 1.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3797) Cys_rich_CPCC PF14206.1 GAK66789.1 - 2.5 7.7 5.6 20 4.8 0.2 3.1 3 0 0 3 3 3 0 Cysteine-rich CPCC Cys_rich_KTR PF14205.1 GAK66789.1 - 2.7 7.5 8.4 66 3.0 0.1 4.0 4 0 0 4 4 4 0 Cysteine-rich KTR zf-MYND PF01753.13 GAK66789.1 - 3.3 7.6 5.5 17 5.3 0.3 2.7 2 1 0 2 2 2 0 MYND finger NOB1_Zn_bind PF08772.6 GAK66789.1 - 3.3 7.5 10.7 5.9 6.7 0.0 3.4 3 1 1 4 4 3 0 Nin one binding (NOB1) Zn-ribbon like zf-Mss51 PF13824.1 GAK66789.1 - 3.9 7.4 10.5 1.5 8.7 1.4 3.0 2 2 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF35_N PF12172.3 GAK66789.1 - 4.1 7.4 9.2 13 5.8 0.0 3.6 4 0 0 4 4 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DNA_RNApol_7kD PF03604.8 GAK66789.1 - 4.8 6.7 12.2 2.1 7.9 0.9 3.5 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_3 PF14369.1 GAK66789.1 - 5.5 7.0 9.8 23 5.0 0.2 3.7 3 1 1 4 4 4 0 zinc-finger Rubredoxin PF00301.15 GAK66789.1 - 6.7 6.6 10.1 16 5.4 0.2 3.8 4 0 0 4 4 4 0 Rubredoxin DUF2296 PF10058.4 GAK66789.1 - 7.1 6.4 7.8 11 5.8 0.0 3.6 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) A2L_zn_ribbon PF08792.5 GAK66789.1 - 8.1 6.0 13.2 3.1 7.3 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain DNA_ligase_ZBD PF03119.11 GAK66789.1 - 8.6 6.1 10.6 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-tcix PF14952.1 GAK66789.1 - 9.4 5.6 14.5 22 4.5 0.2 4.1 4 0 0 4 4 4 0 Putative treble-clef, zinc-finger, Zn-binding Ogr_Delta PF04606.7 GAK66789.1 - 9.5 5.9 10.3 27 4.5 0.1 3.3 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger ThiF PF00899.16 GAK66790.1 - 6.8e-32 110.1 0.0 1.2e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 GAK66790.1 - 0.0002 21.4 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 GAK66790.1 - 0.14 11.3 0.0 2.5 7.2 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain mRNA_cap_enzyme PF01331.14 GAK66791.1 - 7.6e-44 149.7 0.0 9.7e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 GAK66791.1 - 1.1e-13 51.3 0.0 3.6e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 GAK66791.1 - 0.00014 21.3 0.0 0.0046 16.3 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Proteasome PF00227.21 GAK66792.1 - 2.5e-50 170.3 0.2 3.5e-50 169.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pex14_N PF04695.8 GAK66792.1 - 0.58 10.1 3.9 1.1 9.2 1.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cellulase PF00150.13 GAK66794.1 - 3.6e-11 42.7 4.9 1e-10 41.2 3.3 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SIR2 PF02146.12 GAK66795.1 - 1.4e-34 119.3 0.0 6.7e-34 117.1 0.0 2.1 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 GAK66795.1 - 9.8e-05 22.1 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Alpha-L-AF_C PF06964.7 GAK66797.1 - 4.7e-29 101.4 0.0 6.4e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus DUF3505 PF12013.3 GAK66798.1 - 1.8e-09 37.8 4.1 2.7e-09 37.2 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-C2H2_7 PF15269.1 GAK66798.1 - 0.016 15.0 0.4 0.031 14.1 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger zf-C2H2_jaz PF12171.3 GAK66798.1 - 0.03 14.4 1.0 0.065 13.3 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 GAK66798.1 - 0.041 14.1 4.4 0.041 14.1 3.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 GAK66798.1 - 0.62 10.5 9.6 0.15 12.4 2.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAK66798.1 - 0.71 10.0 8.3 1.2 9.2 4.0 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 GAK66798.1 - 1 9.6 4.9 0.5 10.6 1.3 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Bac_rhamnosid PF05592.6 GAK66800.1 - 7.8e-27 93.6 0.0 1.5e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 GAK66800.1 - 0.00017 20.4 0.7 0.00026 19.8 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 LacAB_rpiB PF02502.13 GAK66800.1 - 0.2 11.2 0.1 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase RTA1 PF04479.8 GAK66801.1 - 2.8e-30 105.5 7.6 1.9e-25 89.6 2.8 2.2 2 0 0 2 2 2 2 RTA1 like protein 2OG-FeII_Oxy_2 PF13532.1 GAK66801.1 - 3.1e-11 43.4 0.0 4.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAK66801.1 - 0.00015 22.0 0.0 0.00043 20.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pribosyltran PF00156.22 GAK66802.1 - 1.1e-09 38.1 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Vps51 PF08700.6 GAK66803.1 - 6.9e-18 64.2 0.1 1.4e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 FlgN PF05130.7 GAK66803.1 - 0.021 15.0 0.4 0.068 13.4 0.1 1.9 2 0 0 2 2 2 0 FlgN protein Dor1 PF04124.7 GAK66803.1 - 0.065 11.6 0.1 0.082 11.3 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family COG5 PF10392.4 GAK66803.1 - 0.1 12.5 1.5 0.17 11.8 1.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Usp PF00582.21 GAK66804.1 - 2.3e-22 79.6 0.5 2.3e-22 79.6 0.3 2.5 2 1 0 2 2 2 1 Universal stress protein family Renin_r PF07850.9 GAK66804.1 - 0.12 12.7 0.1 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Renin receptor-like protein Tho2 PF11262.3 GAK66806.1 - 8.5e-76 254.8 0.0 1.4e-75 254.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 GAK66806.1 - 9.2e-29 99.0 0.1 3.1e-28 97.3 0.1 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SSPI PF14098.1 GAK66806.1 - 0.14 12.0 0.0 0.55 10.1 0.0 2.0 1 0 0 1 1 1 0 Small, acid-soluble spore protein I RhoGEF PF00621.15 GAK66807.1 - 1.7e-31 109.5 0.0 3.9e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain RRM_1 PF00076.17 GAK66808.1 - 6.1e-32 109.0 5.2 8.6e-17 60.5 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66808.1 - 2.2e-27 94.7 0.1 1.1e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66808.1 - 4.5e-10 39.2 1.7 0.00079 19.2 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pput2613-deam PF14427.1 GAK66808.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Pput_2613-like deaminase LtrA PF06772.6 GAK66809.1 - 6.5e-15 54.8 24.7 6.3e-09 35.1 5.5 4.0 3 1 0 3 3 3 3 Bacterial low temperature requirement A protein (LtrA) RabGAP-TBC PF00566.13 GAK66810.1 - 2.7e-49 167.5 0.4 4.5e-49 166.8 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Luteo_coat PF00894.13 GAK66810.1 - 0.079 12.7 0.3 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Luteovirus coat protein PPR_2 PF13041.1 GAK66811.1 - 1.6e-18 66.3 0.0 5.7e-05 23.0 0.0 5.1 5 0 0 5 5 5 3 PPR repeat family PPR_1 PF12854.2 GAK66811.1 - 3.1e-16 58.5 1.9 1.5e-07 30.7 0.0 3.9 3 0 0 3 3 3 3 PPR repeat PPR PF01535.15 GAK66811.1 - 5.2e-09 35.4 3.7 0.0021 17.9 0.0 5.1 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 GAK66811.1 - 7.8e-09 35.1 6.3 0.0087 16.2 0.0 7.1 7 0 0 7 7 7 2 Pentatricopeptide repeat domain ABC2_membrane PF01061.19 GAK66812.1 - 6e-85 283.6 64.6 9.8e-44 149.0 15.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAK66812.1 - 1.8e-36 125.4 0.0 6.6e-18 65.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 GAK66812.1 - 2e-25 88.4 6.0 1.9e-20 72.4 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAK66812.1 - 6.5e-09 35.2 49.1 1e-05 24.7 7.1 3.7 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAK66812.1 - 1.2e-06 28.5 0.4 4e-06 26.8 0.3 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 GAK66812.1 - 8.3e-06 25.7 1.7 0.021 14.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 GAK66812.1 - 1e-05 24.9 0.1 0.0096 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAK66812.1 - 2.8e-05 23.6 0.3 0.022 14.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAK66812.1 - 3.2e-05 24.7 0.0 0.14 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 GAK66812.1 - 3.4e-05 23.9 0.0 0.039 13.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 GAK66812.1 - 8.7e-05 22.6 0.0 0.39 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 GAK66812.1 - 0.00027 20.4 0.0 0.26 10.7 0.0 2.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family DUF258 PF03193.11 GAK66812.1 - 0.00032 19.9 0.1 0.0063 15.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 GAK66812.1 - 0.00039 19.9 1.0 0.028 13.8 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 GAK66812.1 - 0.00068 18.9 0.1 0.0073 15.5 0.0 2.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAK66812.1 - 0.001 19.0 0.5 0.39 10.6 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 GAK66812.1 - 0.0045 16.9 0.3 0.12 12.3 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAK66812.1 - 0.005 17.1 2.0 0.65 10.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 GAK66812.1 - 0.0096 15.5 0.5 1.9 8.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 GAK66812.1 - 0.015 14.9 1.4 4 7.0 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 GAK66812.1 - 0.027 13.8 0.3 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 GAK66812.1 - 0.03 14.4 0.9 6.3 7.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase SbcCD_C PF13558.1 GAK66812.1 - 0.086 12.7 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 GAK66812.1 - 0.095 11.7 0.6 2.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 GAK66812.1 - 0.12 12.3 0.4 16 5.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 GAK66812.1 - 0.16 12.1 0.1 22 5.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAK66812.1 - 0.27 11.0 1.9 8.8 6.1 0.2 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 GAK66812.1 - 0.95 9.7 0.0 0.95 9.7 0.0 3.4 5 0 0 5 5 4 0 AAA domain Complex1_LYR_1 PF13232.1 GAK66813.1 - 1.4e-06 28.3 4.6 2.5e-06 27.5 3.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAK66813.1 - 2.6e-06 27.1 7.3 5.1e-06 26.1 5.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) WD40 PF00400.27 GAK66814.1 - 0.029 14.2 0.1 0.67 9.9 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat His_Phos_1 PF00300.17 GAK66815.1 - 3e-12 46.9 0.1 6.2e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF4610 PF15384.1 GAK66815.1 - 0.046 13.2 0.8 0.076 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) DUF3552 PF12072.3 GAK66815.1 - 0.23 10.6 9.6 0.05 12.8 4.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HhH-GPD PF00730.20 GAK66816.1 - 1.3e-08 35.1 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Palm_thioest PF02089.10 GAK66817.1 - 9.6e-57 192.0 0.0 1.3e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 GAK66817.1 - 2.8e-06 27.3 0.0 4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2910 PF11139.3 GAK66817.1 - 0.017 14.2 1.9 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) Abhydrolase_1 PF00561.15 GAK66817.1 - 0.03 13.8 0.1 0.079 12.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 GAK66817.1 - 0.03 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DCAF15_WD40 PF14939.1 GAK66817.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Clat_adaptor_s PF01217.15 GAK66818.1 - 1.1e-17 64.0 0.1 1.7e-15 56.9 0.0 2.2 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 GAK66819.1 - 1.9e-77 259.9 0.0 2.5e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66819.1 - 3.6e-43 147.4 0.0 5.1e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK66819.1 - 5.4e-12 45.2 0.0 1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK66819.1 - 0.0031 16.5 0.0 0.014 14.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sec6 PF06046.8 GAK66819.1 - 0.77 7.7 0.0 1.2 7.1 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Aldo_ket_red PF00248.16 GAK66820.1 - 7.7e-24 83.9 0.0 2.6e-15 55.9 0.0 2.5 2 1 0 2 2 2 2 Aldo/keto reductase family Chitin_synth_1 PF01644.12 GAK66821.1 - 9.9e-65 217.2 0.0 1.5e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 GAK66821.1 - 1.8e-26 92.6 0.2 3.8e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 GAK66821.1 - 3e-26 90.9 0.0 5.5e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 GAK66821.1 - 2.6e-15 56.6 5.4 1.2e-12 47.9 0.1 2.4 1 1 1 2 2 2 2 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK66821.1 - 2.8e-07 30.5 0.0 6.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3989 PF13150.1 GAK66821.1 - 0.25 10.8 0.7 13 5.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) RabGAP-TBC PF00566.13 GAK66822.1 - 2.4e-19 69.6 0.8 5e-16 58.8 0.6 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MFS_1 PF07690.11 GAK66823.1 - 1.5e-24 86.3 33.3 2.1e-24 85.8 23.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAK66823.1 - 0.00061 19.5 0.3 0.002 17.8 0.2 1.9 1 0 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.19 GAK66823.1 - 0.093 11.2 23.6 0.2 10.1 14.5 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter NifU_N PF01592.11 GAK66828.1 - 7.8e-52 174.5 0.1 1.2e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_L11 PF00298.14 GAK66829.1 - 1.4e-27 95.6 2.3 2.3e-27 94.8 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 GAK66829.1 - 3.8e-23 80.6 0.5 3.8e-23 80.6 0.3 2.2 4 0 0 4 4 4 1 Ribosomal protein L11, N-terminal domain NUC153 PF08159.7 GAK66830.1 - 4.5e-12 45.3 0.3 8.8e-12 44.4 0.2 1.5 1 0 0 1 1 1 1 NUC153 domain Ribosomal_S16 PF00886.14 GAK66830.1 - 0.052 13.2 0.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S16 Proteasome PF00227.21 GAK66831.1 - 7.2e-60 201.5 0.0 1.9e-59 200.1 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 GAK66831.1 - 2.8e-10 39.2 0.2 7.7e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RabGAP-TBC PF00566.13 GAK66832.1 - 1.8e-18 66.7 0.0 7e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ras PF00071.17 GAK66833.1 - 7.4e-46 155.4 0.6 9.4e-46 155.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK66833.1 - 5.2e-15 55.9 0.1 8.3e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK66833.1 - 1.7e-06 27.3 0.0 2.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK66833.1 - 3.1e-06 27.1 0.0 5.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK66833.1 - 0.00024 20.5 0.5 0.0012 18.3 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAK66833.1 - 0.0022 17.2 0.1 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAK66833.1 - 0.015 14.5 0.1 0.19 11.0 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 GAK66833.1 - 0.075 12.7 0.1 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase Rpr2 PF04032.11 GAK66834.1 - 8.9e-13 47.9 0.6 3e-12 46.2 0.1 2.0 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_hydro_cc PF11790.3 GAK66835.1 - 3.7e-54 183.6 10.4 5.5e-54 183.1 7.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 GAK66835.1 - 0.00021 20.2 0.2 0.00041 19.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Pol_alpha_B_N PF08418.5 GAK66835.1 - 0.0065 16.0 9.3 1.1 8.6 0.0 2.3 2 1 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal DUF3245 PF11595.3 GAK66835.1 - 1.5 9.0 15.5 0.087 13.0 7.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Macoilin PF09726.4 GAK66835.1 - 3.3 5.8 21.1 4.8 5.3 14.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 GAK66835.1 - 4.8 5.8 12.9 6.9 5.2 9.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SR-25 PF10500.4 GAK66835.1 - 5.2 6.4 31.9 9.3 5.6 22.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_pol_viral_N PF00242.12 GAK66835.1 - 8.3 5.3 14.8 13 4.6 10.2 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Cwf_Cwc_15 PF04889.7 GAK66835.1 - 8.3 6.0 11.5 16 5.1 8.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3818 PF12825.2 GAK66838.1 - 2.8e-77 259.7 0.0 3.5e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 GAK66838.1 - 5e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 PX-associated 3HBOH PF10605.4 GAK66841.1 - 0.015 13.4 0.3 0.017 13.2 0.2 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) PDGLE PF13190.1 GAK66841.1 - 0.018 14.7 0.3 0.028 14.1 0.2 1.5 1 1 0 1 1 1 0 PDGLE domain Peptidase_C13 PF01650.13 GAK66842.1 - 1.9e-40 138.8 0.0 2.5e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF4447 PF14590.1 GAK66842.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4447) RRM_1 PF00076.17 GAK66843.1 - 2.7e-27 94.2 0.0 5.2e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK66843.1 - 6.5e-22 77.3 0.0 2.2e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK66843.1 - 5.2e-12 45.4 0.0 3.7e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAK66843.1 - 0.00015 21.4 0.4 0.058 13.1 0.0 2.5 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 GAK66843.1 - 0.0018 18.1 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 GAK66843.1 - 0.057 13.1 0.0 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SH3_1 PF00018.23 GAK66844.1 - 4.6e-23 80.3 0.0 1.9e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 GAK66844.1 - 8.3e-15 54.1 0.0 2.6e-06 26.9 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 GAK66844.1 - 3.1e-14 52.2 0.0 2.7e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 GAK66844.1 - 3.9e-09 36.2 0.0 1.4e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 PX domain PB1 PF00564.19 GAK66844.1 - 0.095 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 PB1 domain Macoilin PF09726.4 GAK66844.1 - 5.4 5.1 5.3 8.1 4.5 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Adap_comp_sub PF00928.16 GAK66845.1 - 1.9e-43 148.4 0.0 2.6e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAK66845.1 - 0.0019 17.9 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DNA_RNApol_7kD PF03604.8 GAK66846.1 - 2.7e-07 29.9 1.4 5e-07 29.0 1.0 1.4 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2838 PF10998.3 GAK66847.1 - 3.3e-36 123.5 12.0 5.9e-35 119.5 6.7 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2838) DUF4618 PF15397.1 GAK66847.1 - 0.039 13.3 1.7 0.075 12.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) G-gamma PF00631.17 GAK66847.1 - 0.14 11.9 1.4 0.4 10.4 1.0 1.7 1 0 0 1 1 1 0 GGL domain DUF793 PF05633.6 GAK66847.1 - 0.29 9.8 3.6 0.091 11.5 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF793) Seryl_tRNA_N PF02403.17 GAK66847.1 - 3.6 7.6 10.3 0.37 10.8 3.8 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BOP1NT PF08145.7 GAK66848.1 - 1e-105 353.2 3.8 1.5e-105 352.6 2.6 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 GAK66848.1 - 1.9e-22 78.2 13.6 1.5e-06 27.8 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Actin PF00022.14 GAK66849.1 - 3.5e-113 378.0 0.0 6.1e-113 377.2 0.0 1.4 1 1 0 1 1 1 1 Actin adh_short_C2 PF13561.1 GAK66850.1 - 1.7e-30 106.6 0.1 2.2e-30 106.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK66850.1 - 2.7e-28 98.9 2.0 4.3e-28 98.3 1.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK66850.1 - 3.4e-17 62.6 1.8 6e-17 61.8 0.9 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAK66850.1 - 2.3e-05 23.9 0.1 3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAK66850.1 - 0.00027 20.9 0.4 0.0043 17.0 0.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding SBP_bac_5 PF00496.17 GAK66850.1 - 0.00032 19.6 0.0 0.00075 18.4 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Polysacc_synt_2 PF02719.10 GAK66850.1 - 0.0026 16.7 0.4 0.0036 16.2 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 GAK66850.1 - 0.0032 17.1 0.5 0.72 9.4 0.7 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAK66850.1 - 0.0053 17.1 0.8 4.4 7.8 0.2 3.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 GAK66850.1 - 0.0062 15.5 0.4 0.077 11.9 0.2 2.0 1 1 1 2 2 2 2 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 GAK66850.1 - 0.1 11.6 0.2 0.21 10.6 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 GAK66850.1 - 0.12 11.5 1.1 0.21 10.7 0.8 1.4 1 0 0 1 1 1 0 NmrA-like family CoA_binding PF02629.14 GAK66850.1 - 0.12 12.8 0.6 0.58 10.6 0.2 2.1 2 0 0 2 2 2 0 CoA binding domain Rot1 PF10681.4 GAK66852.1 - 1.7e-62 210.5 0.4 2.1e-62 210.2 0.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF2611 PF11022.3 GAK66852.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) SKN1 PF03935.10 GAK66853.1 - 8.5e-196 650.9 0.6 1.1e-195 650.6 0.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DAO PF01266.19 GAK66855.1 - 1.1e-18 67.2 0.0 4.1e-16 58.8 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAK66855.1 - 0.002 18.0 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK66855.1 - 0.0062 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK66855.1 - 0.01 15.8 0.1 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAK66855.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 GAK66855.1 - 0.044 12.8 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.1 GAK66855.1 - 0.084 13.1 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding 2OG-FeII_Oxy PF03171.15 GAK66856.1 - 1.9e-22 79.4 0.0 3.3e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAK66856.1 - 1.6e-18 67.3 0.0 2.7e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PMP1_2 PF08114.6 GAK66857.1 - 0.0011 18.4 0.3 0.0018 17.6 0.2 1.3 1 0 0 1 1 1 1 ATPase proteolipid family DUF262 PF03235.9 GAK66858.1 - 5.1e-13 49.5 0.0 9.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 Pkinase PF00069.20 GAK66859.1 - 4.5e-69 232.4 0.0 7e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66859.1 - 1.4e-30 106.2 0.0 2.2e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK66859.1 - 1.2e-10 40.8 0.6 1.1e-06 27.8 0.0 3.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 GAK66859.1 - 0.024 13.7 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAK66859.1 - 0.15 11.7 0.0 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sedlin_N PF04628.8 GAK66860.1 - 1.9e-33 115.1 0.0 6.5e-33 113.4 0.0 1.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 GAK66860.1 - 0.0001 22.0 0.0 0.00027 20.6 0.0 1.6 1 1 0 1 1 1 1 Sybindin-like family Gly_rich PF12810.2 GAK66860.1 - 0.0029 17.2 1.6 0.0035 16.9 1.1 1.1 1 0 0 1 1 1 1 Glycine rich protein Avl9 PF09794.4 GAK66860.1 - 0.092 11.2 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 bZIP_1 PF00170.16 GAK66861.1 - 2.1e-07 30.7 16.9 4.5e-07 29.7 11.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor eIF3_subunit PF08597.5 GAK66861.1 - 0.011 15.3 0.9 0.015 14.9 0.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF904 PF06005.7 GAK66861.1 - 0.024 14.9 3.0 0.024 14.9 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 GAK66861.1 - 0.026 14.3 24.5 0.12 12.2 8.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 GAK66861.1 - 0.093 13.0 18.4 0.4 10.9 13.0 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor Fib_alpha PF08702.5 GAK66861.1 - 0.15 12.2 4.3 0.2 11.7 3.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 GAK66861.1 - 0.16 11.8 0.4 0.33 10.8 0.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Fucose_iso_N2 PF07882.7 GAK66861.1 - 0.17 11.4 1.4 0.25 10.9 1.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain CENP-F_leu_zip PF10473.4 GAK66861.1 - 0.34 10.7 12.0 1.6 8.5 7.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RasGAP_C PF03836.10 GAK66861.1 - 0.45 10.1 5.3 0.63 9.7 3.3 1.5 1 1 0 1 1 1 0 RasGAP C-terminus DUF724 PF05266.9 GAK66861.1 - 0.5 9.9 10.8 0.76 9.3 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 GAK66861.1 - 0.56 7.9 2.6 0.71 7.6 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4239 PF14023.1 GAK66861.1 - 1.1 8.6 2.8 1.4 8.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF1640 PF07798.6 GAK66861.1 - 2.2 8.2 7.0 3 7.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CDC37_N PF03234.9 GAK66861.1 - 5.9 7.1 8.2 9.8 6.4 5.7 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding APG6 PF04111.7 GAK66861.1 - 8.2 5.3 10.2 11 4.9 7.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GTP_EFTU PF00009.22 GAK66862.1 - 1.7e-46 158.0 0.0 2.9e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAK66862.1 - 1.1e-26 92.9 0.2 4.4e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAK66862.1 - 1.2e-10 41.3 0.8 2.8e-10 40.1 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAK66862.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAK66862.1 - 0.0057 16.2 0.3 0.014 14.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 DNA_pol3_chi PF04364.8 GAK66862.1 - 0.014 15.2 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III chi subunit, HolC Miro PF08477.8 GAK66862.1 - 0.068 13.6 0.1 0.56 10.7 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DAD PF02109.11 GAK66863.1 - 3.6e-48 162.3 1.0 4.4e-48 162.0 0.7 1.0 1 0 0 1 1 1 1 DAD family Rho_GDI PF02115.12 GAK66864.1 - 1.5e-60 204.0 0.0 1.8e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor TauD PF02668.11 GAK66865.1 - 1e-58 199.0 0.5 2.4e-58 197.8 0.4 1.6 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UbiA PF01040.13 GAK66865.1 - 9.9e-24 83.9 26.6 9.9e-24 83.9 18.4 1.6 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF1640 PF07798.6 GAK66865.1 - 1.1e-16 61.4 0.4 1.9e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Cu_amine_oxidN1 PF07833.6 GAK66865.1 - 0.032 14.5 0.1 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain Fzo_mitofusin PF04799.8 GAK66865.1 - 0.37 10.1 2.2 0.68 9.2 1.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region OmpH PF03938.9 GAK66865.1 - 2.5 8.0 16.6 0.056 13.3 3.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pyr_redox PF00070.22 GAK66868.1 - 2.7e-15 56.5 0.1 7.2e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK66868.1 - 2e-12 47.6 0.1 1.1e-05 25.5 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAK66868.1 - 2.1e-12 47.3 0.0 9.5e-12 45.2 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK66868.1 - 2e-07 30.2 0.9 0.011 14.6 0.2 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAK66868.1 - 1.6e-05 24.0 0.2 0.00027 19.9 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 GAK66868.1 - 0.0011 19.2 0.0 0.5 10.6 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Trp_halogenase PF04820.9 GAK66868.1 - 0.0038 15.8 0.7 0.36 9.3 0.1 3.0 3 0 0 3 3 3 1 Tryptophan halogenase TrkA_N PF02254.13 GAK66868.1 - 0.0065 16.4 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.1 GAK66868.1 - 0.015 15.0 4.3 1.3 8.7 0.0 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAK66868.1 - 0.11 11.4 0.5 15 4.3 0.2 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein SRPRB PF09439.5 GAK66869.1 - 2.7e-12 46.2 0.1 6.4e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.16 GAK66869.1 - 3.7e-07 29.5 0.0 5.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK66869.1 - 2.1e-05 24.4 0.0 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK66869.1 - 2.5e-05 23.8 0.2 0.0013 18.2 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 GAK66869.1 - 7.6e-05 23.1 0.1 0.00055 20.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 GAK66869.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras family Proteasome PF00227.21 GAK66870.1 - 8e-46 155.7 0.0 9.8e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAK66870.1 - 2.3e-13 49.1 0.0 4.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF883 PF05957.8 GAK66871.1 - 0.0059 16.9 2.2 0.0059 16.9 1.5 3.5 2 1 2 4 4 4 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 GAK66871.1 - 0.0072 15.8 19.0 0.026 14.0 13.2 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoO PF09769.4 GAK66871.1 - 0.27 10.9 1.1 6.9 6.3 0.7 2.2 1 1 1 2 2 2 0 Apolipoprotein O DBINO PF13892.1 GAK66871.1 - 0.92 9.5 26.6 1.5 8.8 10.5 2.2 1 1 1 2 2 2 0 DNA-binding domain DUF2390 PF09523.5 GAK66871.1 - 1.8 8.7 6.3 0.14 12.3 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2390) ATP-synt_B PF00430.13 GAK66871.1 - 3.5 7.4 37.4 0.95 9.2 8.2 2.8 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) Smac_DIABLO PF09057.5 GAK66871.1 - 7.8 5.5 9.5 14 4.7 6.6 1.4 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases SART-1 PF03343.8 GAK66872.1 - 8.8e-138 460.3 47.7 1.3e-137 459.7 33.1 1.2 1 0 0 1 1 1 1 SART-1 family PQ-loop PF04193.9 GAK66873.1 - 2.9e-32 109.9 0.3 3e-17 61.9 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat UPF0113 PF03657.8 GAK66874.1 - 2.5e-09 37.0 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Utp14 PF04615.8 GAK66875.1 - 3.3e-155 518.1 42.7 3.3e-155 518.1 29.6 2.2 1 1 1 2 2 2 1 Utp14 protein RhoGAP PF00620.22 GAK66876.1 - 1.7e-24 86.1 0.0 3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M23 PF01551.17 GAK66877.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M23 Y_phosphatase PF00102.22 GAK66878.1 - 1.1e-39 136.2 0.0 1.5e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAK66878.1 - 0.0059 16.1 1.7 0.017 14.7 0.4 2.1 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain DSBA PF01323.15 GAK66879.1 - 9.5e-29 100.3 0.0 1.1e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain HpcH_HpaI PF03328.9 GAK66880.1 - 5e-40 136.7 0.2 6.9e-40 136.2 0.2 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 GAK66880.1 - 1.2e-10 40.7 0.3 0.00015 20.7 0.0 2.2 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Aminotran_1_2 PF00155.16 GAK66881.1 - 7e-48 163.4 0.0 1.1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PQ-loop PF04193.9 GAK66882.1 - 1.1e-21 76.1 6.4 4.8e-15 54.8 0.0 3.2 2 1 1 3 3 3 2 PQ loop repeat Pex14_N PF04695.8 GAK66882.1 - 6.1 6.8 8.5 50 3.9 0.0 2.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Endonuclease_NS PF01223.18 GAK66883.1 - 1.5e-50 171.7 0.0 2.5e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease E1_dh PF00676.15 GAK66884.1 - 2.3e-88 295.7 0.1 2.8e-88 295.4 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 GAK66884.1 - 1.7e-06 27.0 0.0 2.7e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 GAK66884.1 - 0.0018 17.2 0.0 0.0079 15.1 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Amidase02_C PF12123.3 GAK66884.1 - 0.11 12.1 0.5 0.25 10.9 0.3 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Aminotran_3 PF00202.16 GAK66886.1 - 4e-78 262.6 0.0 5.7e-78 262.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III TmoB PF06234.7 GAK66886.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) GFO_IDH_MocA PF01408.17 GAK66887.1 - 2.1e-19 70.2 0.1 3.2e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Big_5 PF13205.1 GAK66887.1 - 0.012 16.2 0.5 0.025 15.1 0.4 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain DXP_reductoisom PF02670.11 GAK66887.1 - 0.014 15.9 0.2 0.069 13.6 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Pex19 PF04614.7 GAK66888.1 - 8.9e-68 228.5 1.2 8.9e-68 228.5 0.9 1.6 2 0 0 2 2 2 1 Pex19 protein family HSBP1 PF06825.7 GAK66888.1 - 2.4 7.8 5.2 1.4 8.5 0.3 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 RasGAP_C PF03836.10 GAK66889.1 - 1.5e-46 157.5 5.8 3.8e-46 156.3 4.0 1.7 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 GAK66889.1 - 1.5e-42 145.5 0.0 3.9e-42 144.1 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 GAK66889.1 - 6e-24 81.3 45.2 0.011 15.2 0.1 12.3 12 0 0 12 12 12 11 IQ calmodulin-binding motif CH PF00307.26 GAK66889.1 - 4.7e-11 42.6 0.0 1.3e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Nipped-B_C PF12830.2 GAK66892.1 - 2e-49 167.7 0.6 7.8e-49 165.8 0.4 2.1 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 GAK66892.1 - 7.9e-09 35.2 1.9 7.9e-09 35.2 1.3 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 GAK66892.1 - 0.0036 17.2 0.6 3.6 7.8 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.2 GAK66892.1 - 0.0063 16.3 0.2 0.026 14.3 0.2 2.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Peptidase_M24 PF00557.19 GAK66893.1 - 3.9e-27 95.1 0.3 5.9e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 SH3_2 PF07653.12 GAK66893.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain p450 PF00067.17 GAK66894.1 - 5.7e-75 252.6 0.0 8.4e-59 199.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Ost4 PF10215.4 GAK66894.1 - 2.9 7.4 4.8 7 6.2 1.9 2.5 2 0 0 2 2 2 0 Oligosaccaryltransferase Endosulfine PF04667.12 GAK66895.1 - 3.1e-19 68.7 0.1 6.2e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Porin_3 PF01459.17 GAK66896.1 - 1.5e-67 227.8 0.5 1.7e-67 227.5 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Hpt PF01627.18 GAK66897.1 - 1.6e-09 37.6 0.4 3.4e-09 36.5 0.0 1.7 1 1 1 2 2 2 1 Hpt domain Paf1 PF03985.8 GAK66897.1 - 0.048 12.4 6.2 0.074 11.7 4.3 1.3 1 0 0 1 1 1 0 Paf1 DUF4407 PF14362.1 GAK66897.1 - 5.6 5.8 6.8 9.4 5.0 4.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Arrestin_C PF02752.17 GAK66898.1 - 7.6e-13 48.7 2.2 3.4e-12 46.6 1.2 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAK66898.1 - 1.2e-09 38.2 0.4 0.00072 19.4 0.2 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 GAK66898.1 - 0.019 14.0 1.0 3.7 6.5 0.3 2.4 2 0 0 2 2 2 0 Rgp1 DDHD PF02862.12 GAK66899.1 - 1.3e-46 159.1 0.0 1.3e-46 159.1 0.0 3.7 3 1 0 3 3 3 1 DDHD domain Cupin_8 PF13621.1 GAK66900.1 - 2.3e-21 76.4 0.0 4.5e-21 75.4 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 GAK66900.1 - 6.6e-09 35.4 0.0 3.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 GAK66900.1 - 0.01 16.0 0.0 0.075 13.2 0.0 2.3 1 1 0 1 1 1 0 JmjC domain, hydroxylase AraC_binding PF02311.14 GAK66900.1 - 0.033 13.8 0.0 0.58 9.8 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_2 PF07883.6 GAK66900.1 - 0.06 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Cupin domain DUF883 PF05957.8 GAK66901.1 - 0.086 13.2 4.3 0.22 11.9 3.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Tcp11 PF05794.8 GAK66902.1 - 3e-64 217.3 0.0 9.4e-47 159.7 0.1 3.8 3 1 0 3 3 3 3 T-complex protein 11 Ribosomal_60s PF00428.14 GAK66902.1 - 0.032 14.6 0.3 0.032 14.6 0.2 5.9 6 1 0 6 6 6 0 60s Acidic ribosomal protein NIF PF03031.13 GAK66903.1 - 1.7e-52 177.3 0.1 2.7e-52 176.6 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Macoilin PF09726.4 GAK66903.1 - 2.7 6.1 8.4 4.2 5.5 5.8 1.2 1 0 0 1 1 1 0 Transmembrane protein HLH PF00010.21 GAK66904.1 - 1e-17 63.5 1.5 2.4e-17 62.3 1.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AIP3 PF03915.8 GAK66904.1 - 0.45 9.3 7.8 2.1 7.1 1.8 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 DUF663 PF04950.7 GAK66905.1 - 1.8e-84 283.2 0.0 1.8e-84 283.2 0.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAK66905.1 - 7.6e-30 102.2 0.0 2e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 GAK66905.1 - 5.2e-07 29.2 0.1 4.2e-05 23.0 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAK66905.1 - 1.5e-05 25.1 0.0 5.2e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 GAK66905.1 - 5.2e-05 22.9 0.2 0.00015 21.4 0.1 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 GAK66905.1 - 0.00012 22.1 0.6 0.00052 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 GAK66905.1 - 0.00035 20.0 0.1 0.0012 18.3 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 GAK66905.1 - 0.0013 18.9 0.1 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAK66905.1 - 0.0027 17.8 0.0 0.0071 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 GAK66905.1 - 0.0036 16.9 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 GAK66905.1 - 0.0054 17.2 1.1 0.015 15.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 GAK66905.1 - 0.008 16.0 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAK66905.1 - 0.0091 16.3 2.4 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 GAK66905.1 - 0.012 15.5 0.2 0.047 13.6 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 GAK66905.1 - 0.014 16.1 0.0 0.014 16.1 0.0 4.5 3 1 1 4 4 1 0 AAA domain Arch_ATPase PF01637.13 GAK66905.1 - 0.02 14.5 0.0 0.02 14.5 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Zn_clus PF00172.13 GAK66906.1 - 0.00015 21.5 9.3 0.00028 20.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 GAK66906.1 - 0.026 14.8 0.0 0.069 13.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain PEMT PF04191.8 GAK66908.1 - 6.9e-33 112.9 4.9 1.6e-32 111.7 3.4 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Pkinase PF00069.20 GAK66909.1 - 1.7e-64 217.4 0.0 1.3e-63 214.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK66909.1 - 6.9e-34 117.0 0.0 1.3e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 GAK66909.1 - 9.5e-25 86.1 16.0 3.7e-14 52.2 7.1 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 GAK66909.1 - 5.7e-20 70.8 26.2 1.5e-10 40.6 6.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 GAK66909.1 - 5.7e-08 33.1 0.4 2e-07 31.3 0.3 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAK66909.1 - 0.0026 16.7 0.0 0.0057 15.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF2870 PF11069.3 GAK66909.1 - 0.37 10.8 3.5 0.69 9.9 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Uds1 PF15456.1 GAK66909.1 - 0.42 10.6 10.8 0.5 10.3 2.4 2.8 2 0 0 2 2 2 0 Up-regulated During Septation RhoGAP PF00620.22 GAK66910.1 - 3.8e-10 39.5 0.6 1.7e-09 37.4 0.0 2.4 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.18 GAK66910.1 - 8.4e-05 22.6 0.6 0.0011 19.1 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RIO1 PF01163.17 GAK66911.1 - 6.9e-69 230.9 0.0 6.9e-69 230.9 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Nop14 PF04147.7 GAK66911.1 - 0.42 8.4 38.9 0.0025 15.8 9.8 2.1 2 0 0 2 2 2 0 Nop14-like family Sigma70_ner PF04546.8 GAK66911.1 - 2.9 7.4 33.4 4.8 6.7 5.4 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Hist_deacetyl PF00850.14 GAK66912.1 - 1.7e-61 208.2 3.2 2.6e-61 207.5 2.2 1.3 1 0 0 1 1 1 1 Histone deacetylase domain PQ-loop PF04193.9 GAK66914.1 - 1.3e-34 117.4 3.5 3.6e-18 64.8 0.5 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF3185 PF11381.3 GAK66914.1 - 0.097 12.4 4.2 3.5 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF202 PF02656.10 GAK66914.1 - 0.2 11.9 3.4 0.36 11.0 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4199 PF13858.1 GAK66914.1 - 2.1 8.2 10.5 1.2 9.0 1.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) TBP-binding PF09247.6 GAK66915.1 - 0.056 13.6 0.1 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 TATA box-binding protein binding PHY PF00360.15 GAK66916.1 - 8.7e-25 86.9 0.0 1.7e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 GAK66916.1 - 1.6e-22 79.2 0.2 4e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 GAK66916.1 - 3.6e-15 56.4 0.0 1.2e-14 54.7 0.0 2.0 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.19 GAK66916.1 - 2.1e-14 53.4 0.1 8e-14 51.6 0.1 2.0 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAK66916.1 - 7.7e-12 45.0 0.8 2.5e-11 43.3 0.6 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 GAK66916.1 - 8.9e-10 39.0 0.0 2.4e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold Ras PF00071.17 GAK66918.1 - 1.8e-55 186.7 0.0 2.6e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK66918.1 - 1.3e-14 54.7 0.0 2.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK66918.1 - 8.4e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAK66918.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Asp PF00026.18 GAK66919.1 - 6.1e-17 61.8 0.1 2.1e-11 43.6 0.3 2.6 2 0 0 2 2 2 2 Eukaryotic aspartyl protease DUF4381 PF14316.1 GAK66919.1 - 3.6 7.6 6.7 0.39 10.8 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-C3HC4_3 PF13920.1 GAK66921.1 - 8.4e-10 38.1 16.4 1.5e-09 37.3 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK66921.1 - 8.2 6.5 18.4 15 5.7 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_N PF08240.7 GAK66922.1 - 5.5e-32 109.7 0.2 1e-31 108.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK66922.1 - 1.6e-19 69.7 0.4 4.4e-19 68.3 0.2 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAK66922.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.1 GAK66922.1 - 0.015 14.9 0.2 0.044 13.4 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 GAK66922.1 - 0.017 15.1 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_18 PF12847.2 GAK66922.1 - 0.12 12.9 0.1 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 GAK66923.1 - 9.6e-36 122.5 0.0 1.6e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family DAO PF01266.19 GAK66923.1 - 0.015 14.2 0.3 0.064 12.1 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAK66923.1 - 0.035 13.1 0.1 0.058 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PHZA_PHZB PF03284.8 GAK66923.1 - 0.065 12.3 0.1 0.27 10.3 0.1 2.0 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B ApbA PF02558.11 GAK66923.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3-PAP PF12578.3 GAK66923.1 - 1.1 9.0 7.8 0.071 12.9 1.0 2.3 2 0 0 2 2 2 0 Myotubularin-associated protein ILVD_EDD PF00920.16 GAK66924.1 - 1.4e-192 640.7 1.2 1.6e-192 640.5 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family Mucin PF01456.12 GAK66925.1 - 0.1 12.3 18.3 0.14 11.8 12.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein InvH PF04741.7 GAK66925.1 - 0.58 10.0 3.5 1 9.2 2.5 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF788 PF05620.6 GAK66926.1 - 4.4e-45 153.5 1.9 5.7e-45 153.2 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) HA2 PF04408.18 GAK66928.1 - 3.2e-26 91.3 0.8 1.3e-24 86.1 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAK66928.1 - 5.8e-26 90.5 0.0 1.5e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAK66928.1 - 6.3e-13 48.3 0.0 1.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK66928.1 - 1.8e-06 27.5 0.0 4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAK66928.1 - 1.3e-05 25.3 0.0 0.00044 20.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 GAK66928.1 - 0.00042 19.3 0.0 0.00086 18.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 GAK66928.1 - 0.026 13.9 0.1 0.091 12.1 0.0 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 GAK66928.1 - 0.037 13.7 0.1 0.19 11.4 0.1 2.3 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 GAK66928.1 - 0.12 11.2 0.0 0.8 8.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Atg14 PF10186.4 GAK66929.1 - 2e-25 89.3 0.7 2.6e-13 49.5 0.0 2.7 2 1 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 zf-rbx1 PF12678.2 GAK66930.1 - 0.0012 18.9 0.3 0.0019 18.2 0.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger WD40 PF00400.27 GAK66931.1 - 7.6e-44 146.0 24.9 1.2e-06 28.1 0.0 10.6 11 0 0 11 11 11 8 WD domain, G-beta repeat CTP_transf_2 PF01467.21 GAK66931.1 - 5.5e-08 33.0 0.0 4.6e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase ATE_C PF04377.10 GAK66932.1 - 2.5e-46 156.9 0.1 3.8e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 GAK66932.1 - 2.5e-24 84.9 0.8 2.5e-24 84.9 0.5 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus DSS1_SEM1 PF05160.8 GAK66933.1 - 5.4e-17 61.3 6.7 5.7e-12 45.2 1.1 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family WD40 PF00400.27 GAK66934.1 - 6.8e-16 57.4 10.7 0.02 14.7 0.0 6.3 6 1 1 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 GAK66934.1 - 1.6e-05 24.7 0.0 4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 GAK66934.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain CortBP2 PF09727.4 GAK66934.1 - 0.15 11.5 0.1 0.32 10.4 0.1 1.5 1 0 0 1 1 1 0 Cortactin-binding protein-2 DUF1681 PF07933.9 GAK66935.1 - 1.2e-56 190.6 0.0 1.5e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF3712 PF12505.3 GAK66936.1 - 8.4e-34 116.2 0.0 9.3e-22 77.3 0.0 5.0 5 0 0 5 5 5 3 Protein of unknown function (DUF3712) LEA_2 PF03168.8 GAK66936.1 - 7.7e-06 26.2 0.0 0.022 15.1 0.0 5.0 6 0 0 6 6 6 1 Late embryogenesis abundant protein Apc4 PF12896.2 GAK66937.1 - 2e-29 102.4 0.1 3.4e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ETF PF01012.16 GAK66938.1 - 1.7e-40 138.3 0.3 2.9e-40 137.6 0.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 GAK66938.1 - 2.2e-35 120.1 0.3 4.3e-35 119.1 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DHH PF01368.15 GAK66939.1 - 0.0031 17.1 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 DHH family Glyco_tranf_2_3 PF13641.1 GAK66939.1 - 0.0041 16.9 0.1 0.15 11.8 0.0 2.5 2 1 1 3 3 3 1 Glycosyltransferase like family 2 DHHA1 PF02272.14 GAK66939.1 - 0.0064 16.1 0.0 0.022 14.4 0.0 1.9 1 1 0 1 1 1 1 DHHA1 domain SIR2 PF02146.12 GAK66940.1 - 6.1e-26 91.2 0.0 2.6e-20 72.8 0.0 3.2 3 0 0 3 3 3 2 Sir2 family Rdx PF10262.4 GAK66941.1 - 2e-11 43.7 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Rdx family EB1 PF03271.12 GAK66945.1 - 2.5e-15 56.2 0.4 5.7e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 GAK66945.1 - 1.7e-05 24.8 0.1 3.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain PhaP_Bmeg PF09602.5 GAK66945.1 - 0.024 14.4 0.1 0.055 13.3 0.0 1.6 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF3138 PF11336.3 GAK66945.1 - 0.57 8.2 3.5 0.49 8.5 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Homeobox PF00046.24 GAK66946.1 - 4.6e-12 45.3 1.9 9.3e-12 44.3 1.3 1.5 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 GAK66946.1 - 0.028 14.0 0.1 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain BrkDBD PF09607.5 GAK66946.1 - 0.34 10.5 2.1 0.86 9.2 0.5 2.1 2 0 0 2 2 2 0 Brinker DNA-binding domain SLAC1 PF03595.12 GAK66947.1 - 2e-44 151.5 42.7 4.2e-30 104.5 13.7 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel Mito_carr PF00153.22 GAK66948.1 - 6.4e-31 105.9 6.6 7.3e-14 51.2 0.0 3.2 2 1 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb2_6 PF00562.23 GAK66948.1 - 0.15 10.7 0.1 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 NAD_binding_8 PF13450.1 GAK66949.1 - 3.7e-10 39.6 0.0 1.7e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAK66949.1 - 0.0081 15.9 0.3 0.11 12.2 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding HA2 PF04408.18 GAK66950.1 - 2.1e-16 59.7 0.4 6.4e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAK66950.1 - 3e-12 46.2 0.2 6.3e-12 45.1 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 GAK66950.1 - 1e-07 32.3 0.6 0.0058 17.1 0.0 3.2 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 GAK66950.1 - 2.3e-07 30.4 0.3 5e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 GAK66950.1 - 0.00014 21.6 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold GRP PF07172.6 GAK66950.1 - 1.2 9.6 56.4 6 7.4 1.8 3.8 3 0 0 3 3 3 0 Glycine rich protein family Fungal_trans PF04082.13 GAK66951.1 - 6.8e-10 38.2 0.9 1.3e-09 37.3 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK66951.1 - 0.0015 18.4 10.2 0.0024 17.7 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribophorin_I PF04597.9 GAK66952.1 - 1.2e-112 376.6 0.0 1.3e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I CDC45 PF02724.9 GAK66953.1 - 1.1e-208 694.2 0.0 1.3e-208 694.0 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein RasGEF PF00617.14 GAK66954.1 - 8.6e-44 149.5 0.0 1.4e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAK66954.1 - 3.9e-06 26.9 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 GAK66954.1 - 0.00022 21.6 0.0 0.00043 20.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK66954.1 - 0.046 12.9 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family MobB PF03205.9 GAK66954.1 - 0.099 12.3 0.2 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.17 GAK66954.1 - 0.13 11.6 0.1 0.26 10.6 0.0 1.6 1 1 0 1 1 1 0 Ras family GATA PF00320.22 GAK66955.1 - 4.2e-16 57.9 3.0 8.1e-16 57.0 2.1 1.5 1 0 0 1 1 1 1 GATA zinc finger p450 PF00067.17 GAK66956.1 - 4.5e-66 223.2 0.0 6.2e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIN_2 PF10130.4 GAK66956.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 PIN domain Fungal_trans PF04082.13 GAK66957.1 - 9.2e-10 37.8 0.1 1.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK66957.1 - 3.2e-08 33.3 9.7 5.8e-08 32.5 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH_BEACH PF14844.1 GAK66957.1 - 0.16 11.7 0.3 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH Tnp_zf-ribbon_2 PF13842.1 GAK66957.1 - 2.1 8.8 10.0 4.2 7.8 6.9 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Acetyltransf_1 PF00583.19 GAK66958.1 - 1.3e-15 57.1 0.0 2.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAK66958.1 - 5.6e-12 45.6 0.0 1.6e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAK66958.1 - 1.2e-07 31.9 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAK66958.1 - 3.4e-07 30.4 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAK66958.1 - 7.8e-07 29.1 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAK66958.1 - 1.2e-06 28.4 0.0 1.8e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAK66958.1 - 0.0001 21.9 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAK66958.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 GAK66958.1 - 0.0071 16.1 0.1 0.023 14.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4203 PF13886.1 GAK66958.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Arrestin_C PF02752.17 GAK66959.1 - 7e-12 45.6 0.6 7.1e-10 39.1 0.4 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAK66959.1 - 8e-06 25.7 0.2 0.001 18.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain PMEI PF04043.10 GAK66960.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Nuc_sug_transp PF04142.10 GAK66961.1 - 1.8e-44 151.7 3.9 1.8e-44 151.7 2.7 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 GAK66961.1 - 1.4e-06 28.5 0.5 1.4e-06 28.5 0.3 3.4 3 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 GAK66961.1 - 1.3e-05 24.9 0.6 1.3e-05 24.9 0.4 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 GAK66961.1 - 0.0044 17.0 0.5 0.0044 17.0 0.3 3.3 3 1 0 3 3 3 1 EamA-like transporter family Acyl_transf_3 PF01757.17 GAK66962.1 - 2.6e-11 42.9 32.6 3.7e-11 42.4 22.6 1.2 1 0 0 1 1 1 1 Acyltransferase family Glyco_transf_90 PF05686.7 GAK66963.1 - 6.9e-19 67.8 0.8 9.1e-16 57.5 0.1 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 DUF3315 PF11776.3 GAK66963.1 - 0.069 12.6 3.2 0.094 12.2 1.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3315) Glyco_transf_90 PF05686.7 GAK66964.1 - 1.5e-08 33.7 0.1 5.2e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L22 PF00237.14 GAK66967.1 - 1.5e-21 76.3 0.2 3.8e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e WLM PF08325.5 GAK66968.1 - 0.009 15.9 1.2 0.013 15.3 0.8 1.2 1 0 0 1 1 1 1 WLM domain zf-CHCC PF10276.4 GAK66969.1 - 3.4e-17 61.9 1.3 5.1e-17 61.4 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 GAK66969.1 - 0.00078 19.1 0.0 0.00095 18.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Aminotran_5 PF00266.14 GAK66970.1 - 5.7e-89 298.4 0.0 1.3e-88 297.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Ribosomal_S24e PF01282.14 GAK66970.1 - 0.05 13.3 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S24e DUF2423 PF10338.4 GAK66970.1 - 1.5 8.8 5.2 3 7.8 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) DUF1212 PF06738.7 GAK66971.1 - 2.1e-43 148.0 0.6 2.1e-43 148.0 0.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAK66971.1 - 2e-17 63.3 4.5 2e-17 63.3 3.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) HNH_3 PF13392.1 GAK66972.1 - 0.0011 18.3 0.2 0.0025 17.1 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease EPL1 PF10513.4 GAK66972.1 - 0.04 14.1 1.3 2.4 8.3 0.0 2.4 1 1 1 2 2 2 0 Enhancer of polycomb-like Peptidase_M43 PF05572.8 GAK66973.1 - 1.5e-13 50.6 0.2 2.6e-13 49.8 0.1 1.4 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 GAK66973.1 - 9.6e-08 32.1 1.5 1.3e-07 31.7 1.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 GAK66973.1 - 1.5e-06 28.4 0.8 2.5e-06 27.6 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAK66973.1 - 5.4e-06 26.9 0.8 9e-06 26.2 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 GAK66973.1 - 0.00032 20.3 2.8 0.00085 18.8 1.9 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 GAK66973.1 - 0.034 13.4 0.6 0.054 12.8 0.4 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 GAK66973.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin HNH_3 PF13392.1 GAK66975.1 - 2.6e-09 36.3 0.2 5.4e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease PyrI PF01948.13 GAK66975.1 - 0.051 13.6 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain HNH_3 PF13392.1 GAK66976.1 - 2.9e-16 58.5 5.5 6.1e-09 35.1 0.0 2.8 3 0 0 3 3 3 2 HNH endonuclease AP2 PF00847.15 GAK66976.1 - 0.00057 19.9 0.1 0.0065 16.5 0.0 2.8 3 0 0 3 3 3 1 AP2 domain PyrI PF01948.13 GAK66976.1 - 0.0063 16.5 0.0 0.053 13.5 0.0 2.2 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain Mito_fiss_reg PF05308.6 GAK66976.1 - 7.8 5.7 13.9 0.17 11.2 1.3 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Peptidase_S15 PF02129.13 GAK66977.1 - 1.6e-39 136.0 0.1 5.3e-38 130.9 0.0 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAK66977.1 - 3.6e-26 92.4 0.0 5.8e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Epimerase PF01370.16 GAK66977.1 - 6.1e-25 88.0 0.1 2.2e-24 86.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK66977.1 - 1.3e-13 50.2 0.0 2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAK66977.1 - 3.2e-12 46.6 0.2 6.7e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAK66977.1 - 1.6e-10 40.3 0.0 2.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAK66977.1 - 2.8e-09 37.2 0.0 5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAK66977.1 - 4e-08 33.1 0.1 7.5e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAK66977.1 - 2e-07 30.2 0.0 3.3e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Abhydrolase_6 PF12697.2 GAK66977.1 - 3.6e-07 30.3 0.4 4.6e-06 26.6 0.0 2.6 2 1 1 3 3 3 1 Alpha/beta hydrolase family NAD_binding_4 PF07993.7 GAK66977.1 - 4.9e-05 22.3 0.0 0.00042 19.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Abhydrolase_5 PF12695.2 GAK66977.1 - 0.00035 20.3 0.0 0.0062 16.3 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAK66977.1 - 0.012 15.4 0.0 0.069 13.0 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase NmrA PF05368.8 GAK66977.1 - 0.072 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Peptidase_S9 PF00326.16 GAK66977.1 - 0.16 11.1 0.0 0.52 9.5 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1479 PF07350.7 GAK66978.1 - 1.2e-08 33.8 0.1 0.00053 18.5 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.8 GAK66978.1 - 1.9e-07 31.3 0.0 9.8e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pou PF00157.12 GAK66978.1 - 0.13 11.9 0.1 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain MFS_1 PF07690.11 GAK66980.1 - 1.3e-48 165.5 46.5 1.1e-47 162.4 32.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAK66980.1 - 1.3e-20 73.1 19.6 2.3e-20 72.3 13.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAK66980.1 - 1.1e-11 43.9 13.1 1.1e-11 43.9 9.1 3.3 3 1 2 5 5 5 2 Sugar (and other) transporter UPF0233 PF06781.7 GAK66980.1 - 0.035 13.7 0.4 0.035 13.7 0.2 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) OATP PF03137.15 GAK66980.1 - 4.7 5.1 18.5 0.053 11.5 0.5 3.7 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 GAK66981.1 - 1.1e-21 76.9 22.9 1.1e-21 76.9 15.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK66981.1 - 6.2e-11 41.5 23.0 3.5e-10 39.0 16.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2721 PF11026.3 GAK66981.1 - 0.28 10.8 12.5 0.44 10.1 1.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) SecE PF00584.15 GAK66981.1 - 0.45 10.1 0.1 0.45 10.1 0.0 4.4 5 0 0 5 5 5 0 SecE/Sec61-gamma subunits of protein translocation complex Fungal_trans PF04082.13 GAK66982.1 - 2.8e-19 69.0 0.0 4.9e-19 68.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK66982.1 - 1e-09 38.1 11.4 1.7e-09 37.4 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1680 PF07944.7 GAK66983.1 - 3.9e-30 104.6 0.0 4.5e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Beta-lactamase PF00144.19 GAK66984.1 - 2.8e-34 118.6 0.0 5.2e-34 117.7 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Amino_oxidase PF01593.19 GAK66985.1 - 1.7e-24 86.6 1.2 7.4e-16 58.2 0.1 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAK66985.1 - 1.9e-15 56.5 0.1 1.7e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK66985.1 - 1.4e-07 30.7 0.7 0.0018 17.2 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK66985.1 - 0.00038 20.2 0.3 0.0091 15.7 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAK66985.1 - 0.0024 16.8 0.2 0.0058 15.5 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAK66985.1 - 0.015 15.6 0.1 0.028 14.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAK66985.1 - 0.038 12.8 0.1 0.059 12.2 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 GAK66985.1 - 0.061 13.2 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK66985.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAK66985.1 - 0.095 11.7 1.0 1.3 8.0 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain HALZ PF02183.13 GAK66986.1 - 0.017 14.8 0.7 0.017 14.8 0.5 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper AAA_13 PF13166.1 GAK66986.1 - 1.2 7.5 15.6 0.69 8.2 6.7 2.2 2 0 0 2 2 2 0 AAA domain Fzo_mitofusin PF04799.8 GAK66986.1 - 1.4 8.2 5.4 3.7 6.8 3.7 1.7 1 0 0 1 1 1 0 fzo-like conserved region XhlA PF10779.4 GAK66986.1 - 4.4 7.2 6.4 3.3 7.6 1.2 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Snf7 PF03357.16 GAK66987.1 - 6.2e-23 81.0 8.5 7.3e-23 80.7 5.9 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 GAK66987.1 - 0.00087 18.7 1.8 0.0014 18.1 1.3 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway IMP_cyclohyd PF07826.6 GAK66987.1 - 0.064 12.6 0.1 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein DUF724 PF05266.9 GAK66987.1 - 1.3 8.5 5.3 0.36 10.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) zf-U1 PF06220.7 GAK66988.1 - 2.6e-19 68.4 4.2 3.5e-19 68.0 2.9 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 GAK66988.1 - 0.02 14.9 2.1 0.035 14.2 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SPOB_a PF14689.1 GAK66988.1 - 0.054 13.0 0.5 0.073 12.6 0.3 1.1 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain WD40 PF00400.27 GAK66989.1 - 1.9e-08 33.8 1.9 0.0079 16.0 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Aldedh PF00171.17 GAK66990.1 - 3.6e-158 526.6 3.2 4.2e-158 526.4 2.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAK66990.1 - 0.029 13.6 0.0 0.12 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Mmp37 PF09139.6 GAK66992.1 - 3.8e-107 358.1 0.0 4.4e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Sugar_tr PF00083.19 GAK66993.1 - 4.7e-06 25.4 0.0 6.2e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sigma70_ner PF04546.8 GAK66993.1 - 0.0079 15.8 3.8 0.011 15.3 2.6 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Daxx PF03344.10 GAK66993.1 - 0.75 8.2 6.0 0.95 7.8 4.2 1.3 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 GAK66993.1 - 2.2 7.4 9.3 3.7 6.7 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 GAK66993.1 - 4.1 5.2 9.6 4.7 4.9 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 GAK66993.1 - 4.7 6.4 9.4 7.3 5.7 6.5 1.3 1 0 0 1 1 1 0 SDA1 Sugar_tr PF00083.19 GAK66994.1 - 1e-98 330.8 24.8 1.2e-98 330.6 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK66994.1 - 3.9e-20 71.8 27.7 1.5e-19 69.9 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAK66994.1 - 0.015 15.1 2.6 0.44 10.3 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family SGL PF08450.7 GAK66995.1 - 1.4e-15 57.4 0.1 2.6e-14 53.2 0.1 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region 3-HAO PF06052.7 GAK66998.1 - 4.4e-57 191.7 0.0 5.5e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 GAK66998.1 - 5.7e-06 25.7 0.0 9.4e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAK66998.1 - 0.0003 20.2 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 GAK66998.1 - 0.0075 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.14 GAK66998.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Zn_clus PF00172.13 GAK66999.1 - 0.00065 19.5 9.1 0.0012 18.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAK66999.1 - 0.089 12.9 6.4 0.21 11.8 4.5 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Aldedh PF00171.17 GAK67000.1 - 2.2e-145 484.5 0.0 2.6e-145 484.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAK67000.1 - 2.9e-05 23.4 0.1 8.2e-05 21.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Iso_dh PF00180.15 GAK67001.1 - 9.7e-96 320.7 0.0 1.1e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CHCH PF06747.8 GAK67002.1 - 6.1e-06 26.0 5.7 6.1e-06 26.0 3.9 2.4 2 0 0 2 2 2 1 CHCH domain Pet191_N PF10203.4 GAK67002.1 - 0.16 12.0 11.3 0.68 10.0 6.0 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 zf-C3HC4_2 PF13923.1 GAK67002.1 - 0.46 10.5 3.2 2 8.5 0.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) COX17 PF05051.8 GAK67002.1 - 0.47 10.5 4.5 0.25 11.3 0.9 2.2 1 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 GAK67002.1 - 0.81 9.5 13.0 0.91 9.3 2.8 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like PPR_2 PF13041.1 GAK67003.1 - 9.1e-13 47.9 0.0 3.6e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 GAK67003.1 - 5.7e-08 32.4 3.2 6e-06 26.1 0.0 4.2 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 GAK67003.1 - 6.4e-08 32.0 0.7 1e-05 25.1 0.0 3.6 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.2 GAK67003.1 - 9.9e-05 21.7 1.1 0.028 13.8 0.1 2.7 2 0 0 2 2 2 2 PPR repeat Dioxygenase_C PF00775.16 GAK67004.1 - 3.1e-46 156.9 0.0 4e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAK67004.1 - 6.5e-14 51.6 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 GAK67004.1 - 8.7e-07 28.9 0.0 3e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Sep15_SelM PF08806.6 GAK67005.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Sep15/SelM redox domain Mito_carr PF00153.22 GAK67006.1 - 1.6e-64 213.6 3.1 2.1e-21 75.4 0.3 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Epiglycanin_TR PF05647.6 GAK67006.1 - 4.4 7.1 17.1 0.22 11.3 3.0 2.6 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like AAA_5 PF07728.9 GAK67010.1 - 3.6e-61 204.9 0.0 8.8e-27 93.5 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) Response_reg PF00072.19 GAK67013.1 - 1.2e-21 76.7 0.5 8.2e-15 54.7 0.2 2.4 1 1 1 2 2 2 2 Response regulator receiver domain DUF202 PF02656.10 GAK67014.1 - 9.8e-12 44.9 5.2 9.8e-12 44.9 3.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2615 PF11027.3 GAK67014.1 - 0.46 10.4 0.1 0.46 10.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) LHC PF00556.15 GAK67014.1 - 1 9.2 5.1 0.55 10.1 0.2 2.4 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF3429 PF11911.3 GAK67016.1 - 7.6e-40 136.1 13.2 1.1e-39 135.6 9.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Med2 PF11214.3 GAK67016.1 - 0.37 10.8 10.9 0.75 9.8 7.6 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 RNA_polI_A34 PF08208.6 GAK67016.1 - 1.5 8.4 19.7 2.4 7.7 13.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 COX14 PF14880.1 GAK67017.1 - 0.0028 17.2 0.1 0.0047 16.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly RRM_5 PF13893.1 GAK67018.1 - 9.1e-15 54.2 0.0 9.4e-09 34.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK67018.1 - 3.1e-12 45.9 0.0 1.4e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK67018.1 - 1.1e-07 31.6 0.0 0.002 18.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LigA PF07746.6 GAK67018.1 - 0.055 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Calcipressin PF04847.7 GAK67018.1 - 0.11 12.0 0.3 0.41 10.1 0.0 2.0 2 1 0 2 2 2 0 Calcipressin UDPGP PF01704.13 GAK67019.1 - 2.8e-182 605.9 0.2 3.3e-182 605.6 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase F_actin_cap_B PF01115.12 GAK67020.1 - 2.8e-101 337.7 0.0 3.9e-101 337.2 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit LptE PF04390.7 GAK67020.1 - 0.027 14.2 0.9 0.17 11.5 0.1 2.4 1 1 1 2 2 2 0 Lipopolysaccharide-assembly Cys_Met_Meta_PP PF01053.15 GAK67021.1 - 2.7e-148 493.3 0.0 3.1e-148 493.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAK67021.1 - 8e-12 44.8 0.3 1.2e-11 44.2 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 GAK67021.1 - 1.8e-10 40.1 0.4 3.1e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAK67021.1 - 4.1e-08 32.5 0.1 6.3e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAK67021.1 - 2.7e-05 23.4 0.0 4.2e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 GAK67021.1 - 0.00095 17.5 0.1 0.0015 16.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 GAK67021.1 - 0.0057 15.3 0.0 0.0081 14.9 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 GAK67021.1 - 0.16 10.3 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Arf PF00025.16 GAK67022.1 - 2.6e-77 257.9 0.0 3.1e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAK67022.1 - 1e-12 47.7 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAK67022.1 - 9.5e-11 41.2 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAK67022.1 - 1e-10 40.8 1.2 6.8e-07 28.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAK67022.1 - 1e-09 37.8 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAK67022.1 - 2.3e-07 31.2 0.0 3.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAK67022.1 - 0.00016 21.6 0.0 0.00032 20.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 GAK67022.1 - 0.0012 17.9 0.1 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 GAK67022.1 - 0.044 13.2 0.0 0.25 10.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SPRY PF00622.23 GAK67023.1 - 1.6e-20 73.4 0.1 2.6e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 SPRY domain bZIP_1 PF00170.16 GAK67024.1 - 1.7e-05 24.6 6.9 4.1e-05 23.4 4.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAK67024.1 - 0.14 12.0 5.4 2.1 8.2 4.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper zf-HC5HC2H_2 PF13832.1 GAK67025.1 - 2.2e-20 72.6 24.6 2.6e-20 72.4 1.7 4.1 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAK67025.1 - 6.3e-16 58.3 4.0 6.3e-16 58.3 2.8 4.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.24 GAK67025.1 - 6.6e-14 51.3 24.4 6.9e-10 38.4 4.5 5.7 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 GAK67025.1 - 1.6e-08 33.6 4.3 1.6e-08 33.6 3.0 5.1 7 0 0 7 7 7 2 PHD-finger BAH PF01426.13 GAK67025.1 - 3.7e-08 33.1 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 BAH domain GATA PF00320.22 GAK67025.1 - 1.2e-06 27.7 2.4 1.2e-06 27.7 1.6 3.4 3 0 0 3 3 3 1 GATA zinc finger ELM2 PF01448.19 GAK67025.1 - 0.056 14.0 0.0 0.35 11.5 0.0 2.4 2 0 0 2 2 2 0 ELM2 domain WD40 PF00400.27 GAK67026.1 - 1.5e-07 31.0 5.4 1.8e-05 24.4 0.9 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 GAK67026.1 - 6.4e-06 25.7 0.2 2.1e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.7 GAK67026.1 - 0.0018 17.8 0.6 1 9.1 0.2 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 GAK67026.1 - 0.035 13.2 0.1 0.083 11.9 0.0 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 GAK67026.1 - 0.053 12.0 0.0 1.2 7.5 0.0 2.4 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cyclin PF08613.6 GAK67027.1 - 3.1e-16 60.1 0.0 8.4e-16 58.7 0.0 1.7 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAK67027.1 - 3.3e-07 29.8 0.0 5.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain FAM53 PF15242.1 GAK67028.1 - 1.8 7.9 9.8 1.1 8.7 6.0 1.3 1 1 0 1 1 1 0 Family of FAM53 DUF1880 PF08976.6 GAK67028.1 - 4.7 7.3 7.5 3.2 7.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Rod_cone_degen PF15201.1 GAK67030.1 - 0.085 12.7 0.2 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Progressive rod-cone degeneration AAA PF00004.24 GAK67031.1 - 1.8e-33 115.5 0.0 3.1e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK67031.1 - 4e-09 36.7 0.3 1.3e-08 35.0 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAK67031.1 - 7.4e-08 32.6 0.0 2e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK67031.1 - 1.1e-06 29.4 0.0 2.5e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAK67031.1 - 9.8e-06 25.4 0.0 3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAK67031.1 - 1.4e-05 24.7 0.0 0.00014 21.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 GAK67031.1 - 2.2e-05 24.7 0.0 4.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAK67031.1 - 9.1e-05 21.9 1.6 0.012 15.0 0.0 2.5 1 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAK67031.1 - 0.00011 22.0 0.5 0.0066 16.1 0.3 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_2 PF07724.9 GAK67031.1 - 0.00011 22.1 0.0 0.00029 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 GAK67031.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 GAK67031.1 - 0.00029 20.4 0.0 0.00053 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAK67031.1 - 0.00031 19.8 0.0 0.0006 18.9 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin NACHT PF05729.7 GAK67031.1 - 0.00061 19.4 1.0 0.0032 17.1 0.2 2.3 2 1 0 2 2 1 1 NACHT domain DUF815 PF05673.8 GAK67031.1 - 0.00063 18.7 0.0 0.017 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 GAK67031.1 - 0.00078 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 GAK67031.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 GAK67031.1 - 0.0011 18.6 0.4 0.0044 16.7 0.3 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAK67031.1 - 0.0015 18.6 0.0 0.0041 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 GAK67031.1 - 0.002 18.1 0.1 0.0055 16.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.4 GAK67031.1 - 0.002 17.1 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 GAK67031.1 - 0.0023 17.5 0.0 0.0057 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAK67031.1 - 0.0023 17.0 0.0 0.005 15.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 GAK67031.1 - 0.0033 16.4 0.1 2.1 7.2 0.0 2.2 1 1 1 2 2 2 2 KAP family P-loop domain Viral_helicase1 PF01443.13 GAK67031.1 - 0.0077 15.7 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 GAK67031.1 - 0.0085 15.6 0.1 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 GAK67031.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 GAK67031.1 - 0.013 14.2 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_23 PF13476.1 GAK67031.1 - 0.033 14.5 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAK67031.1 - 0.036 13.2 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 GAK67031.1 - 0.042 13.5 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 GAK67031.1 - 0.05 12.8 0.1 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.4 GAK67031.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 GAK67031.1 - 0.087 11.9 0.4 1 8.4 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.6 GAK67031.1 - 0.096 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAK67031.1 - 0.11 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Rad51 PF08423.6 GAK67031.1 - 0.14 11.0 0.4 2.9 6.7 0.2 2.1 1 1 0 2 2 2 0 Rad51 KTI12 PF08433.5 GAK67031.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Abhydrolase_6 PF12697.2 GAK67032.1 - 7.4e-33 114.3 0.2 9.5e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK67032.1 - 5.9e-16 58.7 0.0 1.1e-14 54.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK67032.1 - 1.6e-14 53.9 0.0 3.8e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAK67032.1 - 6.8e-07 28.7 0.3 0.0075 15.5 0.2 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAK67032.1 - 1.8e-05 24.0 0.1 0.16 11.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.15 GAK67032.1 - 0.00087 19.5 0.1 0.0018 18.5 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 GAK67032.1 - 0.0012 18.4 0.1 0.016 14.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 GAK67032.1 - 0.0015 17.9 0.0 0.0042 16.5 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.3 GAK67032.1 - 0.018 14.9 0.0 0.086 12.7 0.0 2.1 1 1 1 2 2 2 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 GAK67032.1 - 0.024 14.1 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 GAK67032.1 - 0.039 13.2 0.1 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2048 PF09752.4 GAK67032.1 - 0.047 12.5 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DNA_binding_1 PF01035.15 GAK67034.1 - 6.8e-23 80.2 0.0 8.7e-23 79.8 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Smr PF01713.16 GAK67034.1 - 0.16 12.1 0.5 0.54 10.4 0.1 1.9 1 1 1 2 2 2 0 Smr domain SPT16 PF08644.6 GAK67035.1 - 1.8e-55 186.9 0.0 4.4e-55 185.7 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 GAK67035.1 - 4.4e-50 169.3 0.3 1.3e-49 167.8 0.2 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 GAK67035.1 - 8.7e-26 90.7 0.3 2.4e-25 89.3 0.0 1.9 3 0 0 3 3 3 1 Metallopeptidase family M24 Rtt106 PF08512.7 GAK67035.1 - 3.4e-21 75.0 0.1 1.1e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Atg8 PF02991.11 GAK67036.1 - 7.5e-50 167.2 0.1 1.4e-49 166.3 0.1 1.5 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like HEAT_2 PF13646.1 GAK67036.1 - 1.2e-11 44.6 13.0 0.00021 21.5 0.0 5.0 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.17 GAK67036.1 - 1.5e-09 37.1 17.9 0.15 12.2 0.0 9.6 10 0 0 10 10 10 2 HEAT repeat APG12 PF04110.8 GAK67036.1 - 6.5e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Adaptin_N PF01602.15 GAK67036.1 - 0.0025 16.2 0.3 0.039 12.2 0.1 2.5 3 0 0 3 3 3 1 Adaptin N terminal region OPT PF03169.10 GAK67037.1 - 4.4e-183 610.1 50.6 5.2e-183 609.8 35.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CDK2AP PF09806.4 GAK67037.1 - 0.35 11.0 3.0 0.6 10.3 2.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein AChE_tetra PF08674.5 GAK67038.1 - 0.039 13.4 0.1 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain PDEase_II PF02112.10 GAK67039.1 - 3.3e-39 134.7 0.0 3.5e-23 82.0 0.0 3.2 3 1 0 3 3 3 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 GAK67039.1 - 0.00038 20.0 0.0 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF913 PF06025.7 GAK67040.1 - 1.2e-110 369.8 0.0 1.2e-110 369.8 0.0 4.3 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 GAK67040.1 - 6.3e-80 268.9 0.2 6.3e-80 268.9 0.1 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 GAK67040.1 - 2.1e-19 69.3 5.3 2.1e-19 69.3 3.6 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) UBA PF00627.26 GAK67040.1 - 4.9e-09 35.7 0.0 1.6e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain APG6 PF04111.7 GAK67040.1 - 3.8 6.4 9.4 7.4 5.5 6.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 GAK67040.1 - 8.2 4.7 2.6 13 4.0 1.8 1.2 1 0 0 1 1 1 0 AAA domain Cullin PF00888.17 GAK67041.1 - 1.4e-120 403.6 0.0 2e-120 403.1 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAK67041.1 - 6.7e-23 80.2 1.7 1.7e-22 79.0 1.2 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF2407 PF10302.4 GAK67041.1 - 0.0065 16.6 0.0 2.1 8.6 0.3 2.9 2 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Ferritin_2 PF13668.1 GAK67042.1 - 1.7e-44 151.0 1.3 2.8e-44 150.4 0.9 1.3 1 0 0 1 1 1 1 Ferritin-like domain MAPEG PF01124.13 GAK67043.1 - 6.9e-21 74.2 4.1 9.6e-21 73.7 2.8 1.2 1 0 0 1 1 1 1 MAPEG family eIF-5_eIF-2B PF01873.12 GAK67045.1 - 2.1e-39 134.0 0.0 3.2e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 GAK67045.1 - 3.4e-24 84.5 0.0 3.4e-24 84.5 0.0 2.7 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Lon_C PF05362.8 GAK67046.1 - 1.2e-68 230.5 0.0 1.8e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 GAK67046.1 - 6.2e-23 81.4 0.0 1.4e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 GAK67046.1 - 7.2e-11 42.1 0.0 3.1e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 GAK67046.1 - 1.1e-09 38.1 0.0 3e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 GAK67046.1 - 1.3e-08 34.3 0.0 2.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 GAK67046.1 - 4.4e-05 23.4 0.0 0.00026 20.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAK67046.1 - 0.00021 21.3 0.1 0.00021 21.3 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_19 PF13245.1 GAK67046.1 - 0.00023 20.8 0.1 0.00092 18.9 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAK67046.1 - 0.00034 21.4 0.0 0.00034 21.4 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 GAK67046.1 - 0.00037 20.4 0.1 0.0027 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAK67046.1 - 0.00053 20.1 0.0 0.0075 16.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAK67046.1 - 0.004 16.5 0.1 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 GAK67046.1 - 0.0044 16.6 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 GAK67046.1 - 0.0071 15.5 0.1 0.021 13.9 0.0 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 GAK67046.1 - 0.0072 15.0 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 GAK67046.1 - 0.0078 16.5 1.6 0.012 15.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 GAK67046.1 - 0.0082 15.2 0.0 0.084 11.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAK67046.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAK67046.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 GAK67046.1 - 0.024 14.8 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 GAK67046.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAK67046.1 - 0.026 14.0 0.1 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 GAK67046.1 - 0.036 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_PrkA PF08298.6 GAK67046.1 - 0.049 12.3 0.0 0.33 9.6 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain KaiC PF06745.8 GAK67046.1 - 0.075 12.1 0.0 22 4.0 0.0 3.1 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.1 GAK67046.1 - 0.075 13.3 0.5 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 GAK67046.1 - 0.085 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 GAK67046.1 - 0.1 12.5 1.6 0.34 10.8 0.1 2.5 2 1 1 3 3 2 0 AAA domain UPF0079 PF02367.12 GAK67046.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SinI PF08671.5 GAK67046.1 - 0.16 11.4 0.2 0.42 10.0 0.1 1.7 1 0 0 1 1 1 0 Anti-repressor SinI Rad17 PF03215.10 GAK67046.1 - 0.27 9.8 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ResIII PF04851.10 GAK67046.1 - 0.27 11.0 0.1 2.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Bromodomain PF00439.20 GAK67047.1 - 3.2e-17 62.2 0.0 8.1e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain BAH PF01426.13 GAK67047.1 - 5.1e-10 39.1 0.1 8.5e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 BAH domain LSM14 PF12701.2 GAK67048.1 - 2e-31 107.6 0.0 3.1e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 GAK67048.1 - 2.1e-08 34.6 2.0 3.4e-06 27.5 1.4 2.8 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.1 GAK67048.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.8 GAK67048.1 - 4.2 7.1 7.5 5.4 6.8 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1757 PF08560.5 GAK67049.1 - 0.013 15.2 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) LEA_4 PF02987.11 GAK67049.1 - 0.21 11.4 5.5 0.37 10.6 3.8 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF883 PF05957.8 GAK67049.1 - 0.68 10.3 3.2 0.44 10.9 0.7 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Gly-zipper_Omp PF13488.1 GAK67049.1 - 3.9 7.1 17.6 1.7 8.3 0.4 2.6 2 1 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 GAK67049.1 - 8.9 5.9 21.5 0.15 11.6 1.5 3.0 2 1 1 3 3 2 0 YMGG-like Gly-zipper Mannosyl_trans2 PF04188.8 GAK67050.1 - 5.7e-50 170.5 13.8 7.2e-50 170.1 9.6 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Arf PF00025.16 GAK67051.1 - 1.2e-62 210.2 0.0 1.9e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAK67051.1 - 2.2e-11 43.3 0.0 3.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 GAK67051.1 - 4.3e-11 43.3 0.0 1.4e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 GAK67051.1 - 9.3e-11 41.3 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAK67051.1 - 6.8e-10 38.1 0.5 4.5e-08 32.1 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit Methyltransf_23 PF13489.1 GAK67051.1 - 6.9e-10 38.8 0.0 1.4e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK67051.1 - 2.1e-09 37.7 0.0 4.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MMR_HSR1 PF01926.18 GAK67051.1 - 5.9e-08 32.6 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAK67051.1 - 1.5e-06 27.5 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Methyltransf_25 PF13649.1 GAK67051.1 - 9.4e-06 25.9 0.0 2.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GTP_EFTU PF00009.22 GAK67051.1 - 2.4e-05 23.8 0.0 0.0019 17.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Methyltransf_18 PF12847.2 GAK67051.1 - 2.6e-05 24.7 0.0 0.00013 22.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAK67051.1 - 4.4e-05 22.9 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAK67051.1 - 0.00015 21.8 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK67051.1 - 0.00015 21.3 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK67051.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 GAK67051.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) FeoB_N PF02421.13 GAK67051.1 - 0.023 13.9 0.1 0.047 12.9 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B TRAPP PF04051.11 GAK67052.1 - 1e-30 106.2 0.0 1.4e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF837 PF05769.6 GAK67053.1 - 0.0003 20.3 2.4 0.0003 20.3 1.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF837) PBP1_TM PF14812.1 GAK67053.1 - 0.26 11.6 5.1 1 9.6 3.5 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HOOK PF05622.7 GAK67054.1 - 7.9e-52 176.0 73.0 1.4e-50 171.9 36.6 3.6 1 1 1 2 2 2 1 HOOK protein CH PF00307.26 GAK67054.1 - 9.4e-05 22.4 0.1 0.0024 17.8 0.0 2.8 2 0 0 2 2 2 1 Calponin homology (CH) domain Sec20 PF03908.8 GAK67054.1 - 1.3 8.7 19.1 0.13 11.9 1.2 4.7 4 1 1 5 5 5 0 Sec20 Surfac_D-trimer PF09006.6 GAK67054.1 - 4.7 7.0 10.6 25 4.7 0.1 4.2 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation NAD_binding_5 PF07994.7 GAK67055.1 - 1.1e-109 366.4 0.0 1.5e-109 366.0 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 GAK67055.1 - 1.8e-43 146.9 0.0 3.2e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DHHA2 PF02833.9 GAK67055.1 - 0.035 14.2 0.1 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 DHHA2 domain LLC1 PF14945.1 GAK67055.1 - 0.093 13.0 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Cu-oxidase_3 PF07732.10 GAK67056.1 - 9.1e-32 109.2 0.3 2.2e-28 98.3 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAK67056.1 - 9.7e-21 74.3 0.0 1.7e-17 63.7 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAK67056.1 - 3.6e-15 55.6 9.2 9.8e-14 51.0 3.0 4.0 3 1 0 3 3 3 1 Multicopper oxidase DIE2_ALG10 PF04922.7 GAK67057.1 - 5.1e-72 243.0 16.4 7.5e-31 107.5 0.2 3.1 3 0 0 3 3 3 3 DIE2/ALG10 family RtcR PF06956.6 GAK67057.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Mito_carr PF00153.22 GAK67058.1 - 3.8e-49 164.3 3.1 3.3e-17 61.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DOT1 PF08123.8 GAK67059.1 - 6.4e-56 188.9 0.0 8.9e-56 188.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Selenoprotein_S PF06936.6 GAK67059.1 - 0.009 15.5 7.8 0.018 14.5 5.4 1.6 1 0 0 1 1 1 1 Selenoprotein S (SelS) Methyltransf_26 PF13659.1 GAK67059.1 - 0.016 15.2 2.6 0.021 14.8 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.20 GAK67060.1 - 4.9e-72 242.1 0.0 6e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67060.1 - 1.3e-32 112.9 0.0 1.6e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK67060.1 - 2.7e-08 33.1 0.0 9.4e-08 31.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 GAK67060.1 - 0.0018 17.4 0.0 0.0039 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAK67060.1 - 0.0067 15.7 0.1 0.014 14.7 0.1 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 GAK67060.1 - 0.017 14.8 0.8 0.028 14.1 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family 5_nucleotid PF05761.9 GAK67060.1 - 0.02 13.4 0.2 0.037 12.5 0.1 1.4 1 0 0 1 1 1 0 5' nucleotidase family Pkinase PF00069.20 GAK67061.1 - 5.8e-71 238.6 0.0 8e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67061.1 - 3.5e-49 167.2 0.0 4.9e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK67061.1 - 1.8e-06 27.1 0.0 1.4e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.11 GAK67061.1 - 0.054 13.4 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC1 family WW PF00397.21 GAK67063.1 - 1.3e-05 24.8 3.4 2.5e-05 24.0 2.4 1.5 1 0 0 1 1 1 1 WW domain Not1 PF04054.10 GAK67064.1 - 3.6e-107 358.5 0.0 1e-106 357.0 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 GAK67064.1 - 5.4e-55 185.1 4.1 1.7e-54 183.5 2.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DUF572 PF04502.8 GAK67064.1 - 0.05 12.8 1.8 0.098 11.8 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Suf PF05843.9 GAK67064.1 - 0.077 12.7 3.3 0.32 10.6 2.3 2.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DPBB_1 PF03330.13 GAK67065.1 - 0.005 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF399 PF04187.8 GAK67066.1 - 1e-19 70.8 4.3 1.6e-19 70.2 0.3 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF399 EF-hand_4 PF12763.2 GAK67067.1 - 1.4e-37 127.5 0.0 4.3e-15 55.3 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 GAK67067.1 - 8.5e-07 29.0 0.0 0.031 14.3 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.26 GAK67067.1 - 0.00018 21.2 0.0 0.00067 19.4 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain ERM PF00769.14 GAK67067.1 - 0.00051 19.6 23.4 0.001 18.6 16.2 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Macoilin PF09726.4 GAK67067.1 - 0.00067 18.0 10.0 0.0013 17.1 6.9 1.4 1 0 0 1 1 1 1 Transmembrane protein zf-C4H2 PF10146.4 GAK67067.1 - 0.0022 18.0 4.2 0.0022 18.0 2.9 5.0 5 2 0 6 6 4 1 Zinc finger-containing protein EF-hand_1 PF00036.27 GAK67067.1 - 0.0087 15.2 4.1 1.9 7.9 0.0 5.0 6 0 0 6 6 5 1 EF hand UBA_3 PF09288.5 GAK67067.1 - 0.037 13.6 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain CENP-Q PF13094.1 GAK67067.1 - 0.044 13.7 29.8 0.067 13.2 7.4 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.1 GAK67067.1 - 0.091 11.2 15.4 0.13 10.7 10.6 1.0 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 GAK67067.1 - 0.45 9.6 12.9 0.32 10.1 3.7 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMCO5 PF14992.1 GAK67067.1 - 0.53 9.3 19.0 0.89 8.6 13.1 1.3 1 0 0 1 1 1 0 TMCO5 family ATG16 PF08614.6 GAK67067.1 - 0.61 9.8 26.8 1.5 8.5 6.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.1 GAK67067.1 - 0.63 9.4 23.9 0.7 9.2 15.7 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CtIP_N PF10482.4 GAK67067.1 - 0.93 9.2 13.9 1.7 8.4 9.6 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Allexi_40kDa PF05549.6 GAK67067.1 - 1 8.5 6.9 2.1 7.6 4.8 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4201 PF13870.1 GAK67067.1 - 1.8 7.9 22.3 4.2 6.7 15.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Snapin_Pallidin PF14712.1 GAK67067.1 - 3.1 8.1 18.0 2.2 8.6 8.0 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Synaptobrevin PF00957.16 GAK67067.1 - 3.5 7.2 6.0 6.3 6.4 4.2 1.4 1 0 0 1 1 1 0 Synaptobrevin GAS PF13851.1 GAK67067.1 - 5.4 6.1 21.3 5.2 6.2 13.6 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 GAK67067.1 - 5.5 5.9 23.6 10 5.0 8.1 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 PAC2 PF09754.4 GAK67068.1 - 5.9e-25 88.4 0.0 8.1e-25 87.9 0.0 1.3 1 1 0 1 1 1 1 PAC2 family Proteasome PF00227.21 GAK67069.1 - 8.3e-50 168.7 0.1 1e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 GAK67069.1 - 1.1e-09 37.3 0.1 2.4e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DUF4520 PF15016.1 GAK67069.1 - 0.021 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF4116 PF13475.1 GAK67069.1 - 0.048 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Gp-FAR-1 PF05823.7 GAK67069.1 - 0.15 12.0 0.1 1.6 8.6 0.0 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Aminotran_4 PF01063.14 GAK67070.1 - 8e-23 81.1 0.0 4e-22 78.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class IV RNA_POL_M_15KD PF02150.11 GAK67071.1 - 8.8e-13 47.7 2.6 8.8e-13 47.7 1.8 3.2 4 0 0 4 4 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 GAK67071.1 - 1.2e-12 47.1 4.4 6.3e-11 41.7 0.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 GAK67071.1 - 0.0011 19.2 2.3 0.0085 16.3 0.0 2.5 2 1 0 2 2 2 1 Restriction alleviation protein Lar DZR PF12773.2 GAK67071.1 - 0.0025 17.6 2.8 0.65 9.8 0.3 3.1 3 0 0 3 3 3 1 Double zinc ribbon Elf1 PF05129.8 GAK67071.1 - 0.003 17.1 1.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like CpXC PF14353.1 GAK67071.1 - 0.0068 16.3 7.1 1.9 8.4 0.1 3.2 1 1 2 3 3 3 2 CpXC protein Zn-ribbon_8 PF09723.5 GAK67071.1 - 0.014 15.3 7.2 11 6.0 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Crust_neurohorm PF01147.12 GAK67071.1 - 0.058 12.7 2.8 0.41 10.0 0.0 2.3 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Zn_Tnp_IS1595 PF12760.2 GAK67071.1 - 0.11 12.2 8.5 1.8 8.4 1.2 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 GAK67071.1 - 0.13 12.3 8.9 0.88 9.6 0.8 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 GAK67071.1 - 0.18 12.0 3.9 1.3 9.2 0.2 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain GFA PF04828.9 GAK67071.1 - 0.28 11.1 4.5 7.2 6.6 0.1 2.8 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 GAK67071.1 - 0.35 10.1 9.2 1.6 7.9 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.17 GAK67071.1 - 0.66 9.7 4.0 0.8 9.4 0.3 2.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH_5 PF14279.1 GAK67071.1 - 0.72 9.9 3.8 19 5.3 1.2 2.8 2 1 0 2 2 2 0 HNH endonuclease PHD PF00628.24 GAK67071.1 - 0.72 9.5 7.1 0.72 9.5 0.1 2.7 2 1 0 2 2 2 0 PHD-finger DNA_RNApol_7kD PF03604.8 GAK67071.1 - 0.74 9.3 10.5 6.3 6.3 0.0 4.0 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Rubredoxin PF00301.15 GAK67071.1 - 0.82 9.5 6.6 40 4.1 0.0 3.6 4 0 0 4 4 4 0 Rubredoxin Auto_anti-p27 PF06677.7 GAK67071.1 - 0.86 9.4 0.1 0.86 9.4 0.0 2.9 5 0 0 5 5 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3795 PF12675.2 GAK67071.1 - 1 9.6 4.0 4.7 7.4 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) HypA PF01155.14 GAK67071.1 - 3.3 7.4 6.0 0.33 10.6 0.3 2.2 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-3CxxC PF13695.1 GAK67071.1 - 4.1 7.6 6.8 2.8 8.2 0.8 2.6 1 1 1 2 2 2 0 Zinc-binding domain eIF-5_eIF-2B PF01873.12 GAK67071.1 - 5.1 6.7 6.1 6.1 6.5 0.3 2.5 2 1 1 3 3 3 0 Domain found in IF2B/IF5 zf-TFIIB PF13453.1 GAK67071.1 - 5.4 6.2 8.2 11 5.3 0.3 2.8 2 1 1 3 3 3 0 Transcription factor zinc-finger Zn_Tnp_IS1 PF03811.8 GAK67071.1 - 8.2 6.0 7.3 1.9 8.0 0.8 2.7 2 1 0 2 2 2 0 InsA N-terminal domain zf-RING_3 PF14369.1 GAK67071.1 - 8.2 6.5 11.4 3.7 7.6 0.3 2.9 3 0 0 3 3 3 0 zinc-finger DUF3133 PF11331.3 GAK67071.1 - 8.6 6.0 8.7 11 5.6 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3133) zf-UBR PF02207.15 GAK67071.1 - 8.8 6.1 7.8 9.3 6.0 0.8 3.0 3 1 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) DUF2296 PF10058.4 GAK67071.1 - 9.6 6.0 12.9 8.6 6.1 0.2 3.4 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Sel1 PF08238.7 GAK67072.1 - 2.6e-12 46.9 20.7 4.3e-05 24.0 0.1 4.2 4 0 0 4 4 4 3 Sel1 repeat Med7 PF05983.6 GAK67073.1 - 2.9e-48 163.7 0.1 4.2e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 MED7 protein SpoVG PF04026.7 GAK67073.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 SpoVG bZIP_2 PF07716.10 GAK67073.1 - 0.38 10.5 5.1 1.2 9.0 3.6 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Aminotran_5 PF00266.14 GAK67074.1 - 2.6e-31 108.6 0.0 2.4e-30 105.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V RF-1 PF00472.15 GAK67075.1 - 6.2e-22 77.5 3.9 1.2e-21 76.6 2.7 1.4 1 0 0 1 1 1 1 RF-1 domain Chromo PF00385.19 GAK67076.1 - 2.7e-06 26.9 0.2 5.6e-06 25.9 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Y_phosphatase2 PF03162.8 GAK67077.1 - 1.9e-41 141.1 0.0 7.8e-41 139.1 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family E_Pc_C PF06752.7 GAK67077.1 - 1.5 8.3 9.7 2.3 7.6 6.7 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Slx4 PF09494.5 GAK67078.1 - 4.6e-15 55.1 0.0 7.9e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Glyco_hydro_cc PF11790.3 GAK67079.1 - 1.5e-58 198.0 7.6 1.9e-58 197.7 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.12 GAK67079.1 - 0.009 14.4 0.1 0.052 11.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 39 LAM_C PF12544.3 GAK67079.1 - 0.037 14.0 1.6 0.045 13.8 0.2 1.7 2 0 0 2 2 2 0 Lysine-2,3-aminomutase EamA PF00892.15 GAK67080.1 - 1.5e-08 34.7 33.4 4.3e-08 33.2 3.7 3.1 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 GAK67080.1 - 3.3e-08 33.7 4.0 3.3e-08 33.7 2.7 3.0 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Sec20 PF03908.8 GAK67081.1 - 1.1e-16 60.3 1.7 1.1e-16 60.3 1.1 2.5 3 0 0 3 3 3 1 Sec20 Syntaxin-6_N PF09177.6 GAK67081.1 - 0.21 12.0 9.3 0.28 11.6 0.6 3.6 3 2 1 4 4 4 0 Syntaxin 6, N-terminal ATP-synt_B PF00430.13 GAK67081.1 - 2.2 8.1 20.0 2.4 7.9 4.9 3.0 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) MSP1_C PF07462.6 GAK67081.1 - 2.8 6.2 4.5 5.4 5.2 3.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_L16 PF00252.13 GAK67082.1 - 6.6e-41 139.1 0.2 8.2e-41 138.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SNARE PF05739.14 GAK67083.1 - 0.031 13.9 0.0 0.049 13.3 0.0 1.4 1 1 0 1 1 1 0 SNARE domain DUF2803 PF10972.3 GAK67083.1 - 0.057 12.9 0.4 0.063 12.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) DUF3185 PF11381.3 GAK67083.1 - 0.075 12.7 0.1 0.44 10.3 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) HSCB_C PF07743.8 GAK67084.1 - 6.9e-15 55.2 5.3 1.1e-14 54.6 3.7 1.3 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 GAK67084.1 - 2.6e-08 33.4 0.0 6.2e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.2 GAK67084.1 - 0.078 12.7 0.7 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon cwf21 PF08312.7 GAK67084.1 - 0.081 12.7 2.8 0.16 11.8 1.9 1.4 1 0 0 1 1 1 0 cwf21 domain PSP1 PF04468.7 GAK67086.1 - 2.8e-31 107.3 0.4 4.3e-31 106.7 0.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF89 PF01937.14 GAK67087.1 - 2.2e-110 368.7 0.0 2.7e-79 266.5 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 Vma12 PF11712.3 GAK67088.1 - 2.2e-30 105.2 0.8 2.7e-30 104.9 0.1 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PAM2 PF07145.10 GAK67089.1 - 3.6e-06 26.1 5.8 0.14 11.7 0.0 5.3 5 0 0 5 5 5 3 Ataxin-2 C-terminal region SlyX PF04102.7 GAK67089.1 - 0.0029 17.9 4.6 0.0029 17.9 3.2 5.5 6 1 0 6 6 6 1 SlyX GATA PF00320.22 GAK67091.1 - 1.1e-06 27.8 2.5 1.8e-06 27.1 1.7 1.4 1 0 0 1 1 1 1 GATA zinc finger Zn_clus PF00172.13 GAK67092.1 - 5.3e-05 23.0 8.9 9.2e-05 22.2 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EBV-NA3 PF05009.7 GAK67092.1 - 0.06 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Far-17a_AIG1 PF04750.9 GAK67093.1 - 5.3e-06 25.7 12.4 5.3e-06 25.7 8.6 1.9 2 1 0 2 2 2 1 FAR-17a/AIG1-like protein Prp19_bind PF06991.6 GAK67094.1 - 4.5e-55 186.8 17.2 4.5e-55 186.8 11.9 3.3 2 1 1 3 3 3 2 Splicing factor, Prp19-binding domain zf-CCHC PF00098.18 GAK67094.1 - 0.52 10.3 2.8 1.5 8.9 1.9 1.8 1 1 0 1 1 1 0 Zinc knuckle Ras PF00071.17 GAK67095.1 - 1.2e-56 190.5 0.0 1.4e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK67095.1 - 8.8e-18 64.9 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK67095.1 - 2.5e-12 46.3 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK67095.1 - 1.6e-06 28.0 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAK67095.1 - 1.9e-05 23.9 0.0 2.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAK67095.1 - 3.7e-05 23.2 0.0 0.00071 19.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAK67095.1 - 0.00055 20.0 0.0 0.0014 18.7 0.0 1.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAK67095.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 GAK67095.1 - 0.0032 16.9 0.0 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 GAK67095.1 - 0.0038 16.2 0.1 0.053 12.5 0.0 2.2 2 1 0 2 2 2 1 Septin AAA_16 PF13191.1 GAK67095.1 - 0.0052 16.7 0.0 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 GAK67095.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAK67095.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 GAK67095.1 - 0.0086 15.5 0.0 0.029 13.8 0.0 1.7 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 GAK67095.1 - 0.0096 15.4 0.3 0.6 9.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 GAK67095.1 - 0.011 15.5 0.0 0.06 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 GAK67095.1 - 0.013 14.9 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 GAK67095.1 - 0.02 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 GAK67095.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 GAK67095.1 - 0.035 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAK67095.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 GAK67095.1 - 0.097 11.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ATG16 PF08614.6 GAK67096.1 - 9.8e-62 208.2 17.1 1.5e-61 207.6 11.8 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 GAK67096.1 - 0.09 12.6 1.2 14 5.7 0.2 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) UvrD_C_2 PF13538.1 GAK67096.1 - 0.11 12.6 0.2 5.7 7.1 0.0 2.8 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain CENP-H PF05837.7 GAK67096.1 - 0.31 11.2 18.0 0.8 9.9 1.5 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) IncA PF04156.9 GAK67096.1 - 0.84 9.1 21.6 1.7 8.1 14.4 2.0 1 1 0 1 1 1 0 IncA protein DUF3138 PF11336.3 GAK67096.1 - 1.1 7.3 9.1 0.081 11.0 2.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF972 PF06156.8 GAK67096.1 - 2.3 8.6 14.6 0.92 9.8 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4094 PF13334.1 GAK67096.1 - 2.7 8.4 5.9 3.6 8.0 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DASH_Dam1 PF08653.5 GAK67096.1 - 4 7.2 5.1 24 4.7 0.4 2.9 3 1 0 3 3 3 0 DASH complex subunit Dam1 TMF_TATA_bd PF12325.3 GAK67096.1 - 4.3 7.0 24.8 0.17 11.6 6.1 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Lectin_N PF03954.9 GAK67096.1 - 7.8 5.9 9.5 0.67 9.3 1.6 2.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Actin PF00022.14 GAK67097.1 - 1.2e-53 182.0 0.0 3.3e-26 91.6 0.0 2.4 2 1 0 2 2 2 2 Actin LMBR1 PF04791.11 GAK67097.1 - 0.87 8.0 6.2 2.4 6.6 0.6 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Nop52 PF05997.7 GAK67098.1 - 1.2e-69 234.0 0.0 2e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 GTP_EFTU PF00009.22 GAK67098.1 - 1e-23 83.7 0.0 2.1e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAK67098.1 - 4.5e-09 36.3 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAK67098.1 - 4.3e-06 26.7 0.9 1.2e-05 25.3 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 GAK67098.1 - 8.1e-05 22.1 2.3 0.00013 21.4 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 GAK67098.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2146 PF10220.4 GAK67098.1 - 9 4.1 5.5 13 3.6 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) MRP-L46 PF11788.3 GAK67099.1 - 2.8e-25 89.1 0.4 6e-25 88.0 0.3 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 GAK67099.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Med3 PF11593.3 GAK67099.1 - 0.054 12.7 0.0 0.054 12.7 0.0 2.3 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal V-ATPase_H_N PF03224.9 GAK67100.1 - 1.7e-102 342.7 0.0 2.9e-102 341.9 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 GAK67100.1 - 7e-40 135.6 0.0 1.5e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.18 GAK67100.1 - 0.014 15.1 7.0 0.41 10.5 0.3 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Synthase_beta PF11421.3 GAK67100.1 - 0.016 15.8 4.0 0.016 15.8 2.8 2.5 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Peptidase_A17 PF05380.8 GAK67100.1 - 0.035 13.9 0.0 0.073 12.9 0.0 1.6 1 1 0 1 1 1 0 Pao retrotransposon peptidase HEAT PF02985.17 GAK67100.1 - 0.042 13.9 0.0 0.71 10.1 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Adaptin_N PF01602.15 GAK67100.1 - 0.12 10.6 0.2 3.5 5.8 0.0 2.6 3 0 0 3 3 3 0 Adaptin N terminal region GSH_synth_ATP PF03917.12 GAK67101.1 - 1.4e-99 333.2 0.0 1.7e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 GAK67101.1 - 7.4e-33 112.7 0.0 1.4e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Med31 PF05669.7 GAK67102.1 - 3.6e-28 97.3 0.1 4.3e-28 97.0 0.1 1.1 1 0 0 1 1 1 1 SOH1 TPT PF03151.11 GAK67103.1 - 4.8e-31 107.4 5.1 4.8e-31 107.4 3.5 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 GAK67103.1 - 6.8e-10 39.0 24.3 5.1e-05 23.3 5.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 GAK67103.1 - 0.00014 20.9 17.3 0.0021 17.0 12.0 2.3 1 1 0 1 1 1 1 UAA transporter family eIF3_subunit PF08597.5 GAK67103.1 - 0.27 10.7 5.8 0.5 9.8 4.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit adh_short_C2 PF13561.1 GAK67104.1 - 1.2e-27 97.2 0.0 1.5e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK67104.1 - 1.1e-23 84.0 0.0 1.4e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK67104.1 - 2.3e-09 37.1 0.0 3.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 KR domain TraK PF06586.6 GAK67104.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 TraK protein TPR_1 PF00515.23 GAK67105.1 - 2.5e-55 181.9 26.3 6.3e-08 31.9 0.0 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAK67105.1 - 4.7e-51 166.6 19.6 7.1e-06 25.5 0.0 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 GAK67105.1 - 1.8e-47 158.8 40.6 9.9e-13 47.5 3.5 6.6 3 2 5 8 8 8 8 TPR repeat TPR_8 PF13181.1 GAK67105.1 - 1.2e-34 115.4 14.8 0.00018 21.0 2.4 10.4 7 2 3 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 GAK67105.1 - 3.9e-29 100.4 18.8 3.9e-06 26.6 2.0 6.6 1 1 4 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAK67105.1 - 7.3e-29 97.2 5.9 0.0039 16.8 0.0 9.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAK67105.1 - 9.3e-29 97.2 19.5 0.00013 21.8 0.3 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAK67105.1 - 9.5e-29 97.2 20.3 0.00048 20.5 0.0 10.6 4 3 7 11 11 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 GAK67105.1 - 1.1e-26 92.8 47.6 1e-07 32.3 0.3 9.7 6 2 4 10 10 9 7 Tetratricopeptide repeat TPR_6 PF13174.1 GAK67105.1 - 2.6e-22 77.6 12.3 0.0016 18.7 0.0 10.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAK67105.1 - 1.1e-21 76.9 21.3 2.7e-06 27.6 0.2 6.9 4 2 5 9 9 8 7 Tetratricopeptide repeat TPR_9 PF13371.1 GAK67105.1 - 8.5e-16 57.5 12.0 0.0025 17.6 0.1 6.3 1 1 6 8 8 8 8 Tetratricopeptide repeat Apc3 PF12895.2 GAK67105.1 - 2.8e-12 46.5 9.5 1.4e-06 28.3 1.3 4.5 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAK67105.1 - 9.9e-09 34.6 10.0 0.0023 17.0 1.3 5.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 GAK67105.1 - 0.00094 19.2 3.2 0.02 15.0 0.1 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAK67105.1 - 0.013 15.4 14.7 2.2 8.3 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TOM20_plant PF06552.7 GAK67105.1 - 0.016 14.7 0.6 9 5.8 0.2 3.4 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2225 PF09986.4 GAK67105.1 - 0.021 14.2 3.7 1.4 8.3 1.0 2.7 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 GAK67105.1 - 0.022 13.5 0.7 1.5 7.5 0.1 2.6 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Rapsyn_N PF10579.4 GAK67105.1 - 0.084 12.6 0.2 22 4.9 0.0 3.5 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.1 GAK67105.1 - 1.8 8.4 8.9 50 3.8 0.0 5.4 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 GAK67105.1 - 4.2 7.2 18.5 20 5.1 1.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1676 PF07898.8 GAK67106.1 - 0.0037 17.5 2.7 0.011 16.0 1.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) Cellulose_synt PF03552.9 GAK67106.1 - 2.3 6.4 2.2 1 7.5 0.0 1.4 2 0 0 2 2 2 0 Cellulose synthase Med15 PF09606.5 GAK67106.1 - 9.2 4.3 58.8 2.4 6.2 35.7 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Oxysterol_BP PF01237.13 GAK67107.1 - 2.4e-90 302.5 0.0 3.4e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Phage_stabilise PF11134.3 GAK67107.1 - 0.009 14.6 0.1 0.013 14.0 0.0 1.1 1 0 0 1 1 1 1 Phage stabilisation protein RNR_inhib PF08591.5 GAK67108.1 - 0.0026 18.6 2.7 0.0032 18.3 0.8 2.2 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor NTF2 PF02136.15 GAK67109.1 - 2.8e-08 34.1 0.1 6.3e-07 29.7 0.0 2.6 3 0 0 3 3 3 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 GAK67109.1 - 3.8e-08 33.2 0.0 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Cys_Met_Meta_PP PF01053.15 GAK67110.1 - 2.1e-120 401.5 0.0 3e-120 401.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 GAK67110.1 - 9.4e-19 67.2 2.4 6.7e-18 64.5 2.0 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAK67110.1 - 3.8e-07 30.2 0.9 1.4e-06 28.3 0.1 2.3 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 GAK67110.1 - 0.0057 15.9 1.4 0.019 14.1 0.1 2.4 2 0 0 2 2 2 1 Galactokinase galactose-binding signature DPBB_1 PF03330.13 GAK67111.1 - 2.5e-06 27.4 0.0 1e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel MIP-T3 PF10243.4 GAK67111.1 - 0.00015 20.4 20.6 0.00023 19.7 14.3 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Barwin PF00967.12 GAK67111.1 - 0.012 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Barwin family Totivirus_coat PF05518.6 GAK67111.1 - 0.027 12.3 11.4 0.035 11.9 7.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein Mitofilin PF09731.4 GAK67111.1 - 0.13 10.8 16.4 0.21 10.2 11.3 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.8 GAK67111.1 - 0.8 9.5 31.9 1.4 8.6 22.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 GAK67111.1 - 1.3 7.1 48.2 1.6 6.8 33.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec15 PF04091.7 GAK67112.1 - 5.5e-78 262.4 0.0 1.7e-77 260.7 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 GAK67112.1 - 5.4e-05 22.9 0.3 0.00014 21.6 0.1 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.9 GAK67112.1 - 8.6e-05 22.2 1.8 0.00015 21.4 0.3 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG5 PF10392.4 GAK67112.1 - 0.00058 19.8 1.2 0.002 18.0 0.2 2.4 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 GAK67112.1 - 0.0044 16.8 0.0 0.018 14.8 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DUF866 PF05907.8 GAK67114.1 - 2.8e-42 143.9 0.0 3.2e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 GAK67114.1 - 0.0061 16.1 0.7 0.01 15.4 0.5 1.4 1 0 0 1 1 1 1 Cytochrome c7 zf-CHY PF05495.7 GAK67114.1 - 0.0064 16.6 0.5 0.012 15.7 0.4 1.3 1 0 0 1 1 1 1 CHY zinc finger Ribosomal_L44 PF00935.14 GAK67114.1 - 0.051 13.5 0.7 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L44 Cytochrome_C554 PF13435.1 GAK67114.1 - 0.11 12.5 2.6 0.24 11.4 1.8 1.6 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 GAK67114.1 - 0.38 11.1 4.2 1.4 9.3 3.0 1.8 1 1 1 2 2 2 0 Cytochrome c3 Tyrosinase PF00264.15 GAK67115.1 - 2.4e-20 73.6 5.4 4e-20 72.9 3.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF423 PF04241.10 GAK67118.1 - 3.1e-26 91.1 1.0 2.3e-25 88.3 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Androgen_recep PF02166.11 GAK67118.1 - 0.07 11.9 0.3 0.079 11.8 0.2 1.1 1 0 0 1 1 1 0 Androgen receptor HLH PF00010.21 GAK67119.1 - 2e-12 46.5 0.0 5.7e-12 45.1 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AMP-binding_C PF13193.1 GAK67119.1 - 4e-05 24.4 0.0 9.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sporozoite_P67 PF05642.6 GAK67119.1 - 0.53 8.0 4.1 0.77 7.5 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tom22 PF04281.8 GAK67119.1 - 0.62 9.6 8.7 7 6.1 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 SNF2_N PF00176.18 GAK67120.1 - 2.9e-68 229.8 0.0 4.9e-68 229.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK67120.1 - 1.4e-15 56.9 0.0 4.3e-15 55.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 GAK67120.1 - 7.3e-12 44.9 10.1 7.3e-12 44.9 7.0 3.1 3 0 0 3 3 3 1 HSA HDA2-3 PF11496.3 GAK67120.1 - 0.044 12.6 0.1 7.2 5.3 0.0 2.6 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Dabb PF07876.7 GAK67121.1 - 8.3e-14 51.8 0.0 9.2e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Zn_clus PF00172.13 GAK67122.1 - 5.8e-09 35.7 8.4 9.9e-09 34.9 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP90 PF00183.13 GAK67122.1 - 0.095 11.0 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Hsp90 protein DEAD PF00270.24 GAK67123.1 - 1.2e-43 148.5 1.3 1.5e-43 148.2 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK67123.1 - 1.4e-27 95.3 0.5 1.4e-26 92.1 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 GAK67123.1 - 0.00021 20.9 0.2 0.00075 19.2 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 GAK67123.1 - 0.00096 19.0 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 GAK67123.1 - 0.021 14.4 0.1 0.06 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 GAK67123.1 - 0.023 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 GAK67123.1 - 0.059 13.5 0.3 0.19 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 GAK67123.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase zf-C3HC4_3 PF13920.1 GAK67124.1 - 3.4e-06 26.6 6.0 3.4e-06 26.6 4.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK67124.1 - 1.5 8.5 18.0 0.04 13.5 6.1 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Chitin_synth_2 PF03142.10 GAK67125.1 - 1.3e-240 799.2 0.1 2e-240 798.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase DASH_Dad1 PF08649.5 GAK67125.1 - 2.4e-18 65.5 0.0 4.5e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad1 Glyco_trans_2_3 PF13632.1 GAK67125.1 - 2.1e-14 53.6 4.5 2.1e-14 53.6 3.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK67125.1 - 9.7e-12 45.1 0.2 8.7e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAK67125.1 - 0.001 18.3 0.1 0.1 11.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 GAK67125.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 GAK67125.1 - 0.19 11.3 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 DSPc PF00782.15 GAK67127.1 - 1e-07 31.5 0.0 2.9e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 GAK67127.1 - 0.0022 17.4 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 GAK67127.1 - 0.004 16.5 0.4 0.019 14.2 0.3 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAK67127.1 - 0.078 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate BSD PF03909.12 GAK67128.1 - 4.3e-20 71.2 0.0 3e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 GAK67128.1 - 4.5e-16 58.2 0.0 1e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain ORC6 PF05460.8 GAK67128.1 - 0.54 9.2 6.0 1.2 8.1 4.2 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hid1 PF12722.2 GAK67129.1 - 8.5e-119 397.6 0.0 2.5e-104 349.7 0.0 3.8 2 1 1 3 3 3 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 GAK67129.1 - 4e-55 187.1 0.0 2.1e-53 181.5 0.0 2.2 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Inhibitor_G39P PF11417.3 GAK67129.1 - 0.094 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P PPP4R2 PF09184.6 GAK67129.1 - 0.18 11.2 6.6 0.28 10.6 4.6 1.2 1 0 0 1 1 1 0 PPP4R2 GET2 PF08690.5 GAK67130.1 - 0.0051 16.1 5.5 0.61 9.2 0.2 2.7 2 1 0 2 2 2 2 GET complex subunit GET2 PMT PF02366.13 GAK67131.1 - 3.6e-69 232.8 18.6 3.6e-69 232.8 12.9 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAK67131.1 - 1.9e-25 89.5 4.1 4.5e-25 88.3 2.8 1.6 1 1 0 1 1 1 1 MIR domain NAC PF01849.13 GAK67133.1 - 7.5e-21 73.4 0.0 1.4e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 GAK67133.1 - 0.00053 19.7 0.1 0.0012 18.5 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF399 PF04187.8 GAK67133.1 - 0.026 13.9 2.0 0.04 13.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF399 YbaB_DNA_bd PF02575.11 GAK67133.1 - 1.5 8.7 12.1 0.78 9.6 6.4 1.9 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Fe-S_biosyn PF01521.15 GAK67134.1 - 1.9e-14 53.5 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CDC37_N PF03234.9 GAK67135.1 - 8.4e-53 179.3 5.2 1.8e-52 178.1 3.1 2.0 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 GAK67135.1 - 1.1e-28 99.8 0.3 7.3e-23 80.9 0.0 2.5 2 0 0 2 2 2 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 GAK67135.1 - 1.2e-22 79.5 1.5 3.6e-22 78.0 0.2 2.4 2 0 0 2 2 2 1 Cdc37 C terminal domain HTH_22 PF13309.1 GAK67135.1 - 0.028 14.1 0.7 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 HTH domain DUF1993 PF09351.5 GAK67135.1 - 0.078 12.8 0.3 0.87 9.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Adeno_VII PF03228.9 GAK67135.1 - 0.18 12.4 5.4 0.38 11.3 0.0 3.5 4 0 0 4 4 4 0 Adenoviral core protein VII COG7 PF10191.4 GAK67136.1 - 3e-39 134.5 13.8 7.3e-36 123.4 8.3 2.4 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) MOFRL PF05161.8 GAK67136.1 - 0.025 14.6 0.1 0.11 12.6 0.1 2.1 1 0 0 1 1 1 0 MOFRL family RNase_PH PF01138.16 GAK67137.1 - 7e-23 81.3 0.2 1.4e-22 80.3 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAK67137.1 - 0.022 14.7 0.0 0.13 12.1 0.0 2.4 2 1 0 2 2 2 0 3' exoribonuclease family, domain 2 PUF PF00806.14 GAK67138.1 - 8.5e-17 59.6 0.0 8e-05 21.9 0.0 4.9 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat MyTH4 PF00784.12 GAK67138.1 - 0.042 13.7 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 MyTH4 domain SH3BGR PF04908.10 GAK67139.1 - 2.9e-08 33.5 0.0 6.9e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein COX4 PF02936.9 GAK67140.1 - 1.4e-28 99.3 1.2 7.7e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 Cytochrome c oxidase subunit IV HlyD PF00529.15 GAK67140.1 - 0.028 13.7 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein HMG_box_2 PF09011.5 GAK67140.1 - 0.55 10.6 2.9 5.1 7.5 0.1 2.6 1 1 1 2 2 2 0 HMG-box domain HAD_2 PF13419.1 GAK67141.1 - 1.2e-16 61.4 0.0 2.4e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAK67141.1 - 1.4e-06 28.9 0.0 2.8e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAK67141.1 - 2.3e-06 27.2 0.0 5.6e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Ion_trans PF00520.26 GAK67142.1 - 7.5e-103 341.9 63.2 2.7e-36 124.7 1.8 5.1 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 GAK67142.1 - 0.00065 18.2 7.5 0.00065 18.2 5.2 6.9 7 1 1 8 8 8 5 Polycystin cation channel Proteasome PF00227.21 GAK67143.1 - 7.7e-59 198.1 0.1 9.9e-59 197.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAK67143.1 - 1.2e-14 53.3 0.1 1.2e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SNARE_assoc PF09335.6 GAK67144.1 - 6.7e-13 48.9 2.2 2e-12 47.3 1.5 1.9 1 0 0 1 1 1 1 SNARE associated Golgi protein PCI PF01399.22 GAK67144.1 - 7.8e-10 39.0 0.5 3e-09 37.1 0.1 2.3 2 0 0 2 2 2 1 PCI domain Peptidase_M15_2 PF05951.8 GAK67144.1 - 0.14 11.6 2.1 0.45 9.9 0.0 2.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF882) DUF3439 PF11921.3 GAK67144.1 - 0.55 9.9 12.5 1.3 8.7 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF382 PF04037.8 GAK67145.1 - 5.8e-60 200.7 0.7 5.8e-60 200.7 0.5 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 GAK67145.1 - 3.5e-19 67.9 4.1 7.1e-19 66.9 2.8 1.5 1 0 0 1 1 1 1 PSP DSPc PF00782.15 GAK67147.1 - 4.2e-23 81.3 0.0 4.5e-19 68.3 0.1 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAK67147.1 - 0.00034 20.0 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MFS_1 PF07690.11 GAK67148.1 - 9.8e-24 83.7 41.3 3.3e-23 81.9 28.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_4 PF05105.7 GAK67148.1 - 0.076 12.6 0.3 0.19 11.4 0.2 1.6 1 0 0 1 1 1 0 Holin family AMP-binding PF00501.23 GAK67149.1 - 4e-65 219.8 0.0 5.2e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme JmjC PF02373.17 GAK67152.1 - 1.7e-38 131.3 0.1 1.7e-38 131.3 0.1 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 GAK67152.1 - 3.9e-15 55.0 0.1 9e-15 53.9 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.1 GAK67152.1 - 5.5e-10 39.2 1.8 1.6e-09 37.7 1.2 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAK67152.1 - 3.6e-09 36.6 2.5 9e-09 35.3 1.8 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.3 GAK67152.1 - 0.12 12.3 1.7 0.27 11.2 1.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain TPR_11 PF13414.1 GAK67153.1 - 2.9e-09 36.4 0.0 2.9e-09 36.4 0.0 3.2 4 0 0 4 4 4 1 TPR repeat UBA PF00627.26 GAK67153.1 - 4.9e-06 26.2 0.0 6.3e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.26 GAK67153.1 - 9e-06 25.3 0.7 2.2e-05 24.0 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain UPF0121 PF03661.8 GAK67154.1 - 4.1e-23 81.8 2.9 5.8e-23 81.3 2.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Abi PF02517.11 GAK67154.1 - 0.091 12.9 7.8 0.3 11.2 0.7 2.5 2 0 0 2 2 2 0 CAAX protease self-immunity Sororin PF09666.5 GAK67155.1 - 0.022 14.9 0.2 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 Sororin protein TPR_12 PF13424.1 GAK67156.1 - 1.7e-12 47.1 32.0 2.2e-05 24.3 0.4 8.9 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAK67156.1 - 6.3e-07 28.7 10.4 0.027 14.2 0.1 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat AAA_22 PF13401.1 GAK67156.1 - 4.4e-05 23.6 0.1 0.00096 19.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain TPR_14 PF13428.1 GAK67156.1 - 0.00027 21.2 10.1 0.12 13.1 0.1 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAK67156.1 - 0.0012 19.1 4.3 1.2 9.5 0.1 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAK67156.1 - 0.0026 18.3 5.0 0.012 16.2 0.3 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_18 PF13238.1 GAK67156.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.1 GAK67156.1 - 0.021 14.7 18.4 0.38 10.7 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAK67156.1 - 0.029 14.2 18.4 2.5 8.2 0.0 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAK67156.1 - 0.13 12.7 3.2 19 5.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAK67156.1 - 8 6.2 10.3 25 4.6 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_S30AE PF02482.14 GAK67158.1 - 0.054 13.9 0.1 0.08 13.3 0.1 1.3 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein MFS_1 PF07690.11 GAK67159.1 - 1.1e-17 63.8 95.9 2e-16 59.6 39.5 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily CMD PF02627.15 GAK67160.1 - 5.2e-20 71.0 0.2 3.7e-19 68.3 0.1 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Methyltransf_24 PF13578.1 GAK67160.1 - 3e-09 37.6 0.0 6.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_RNA PF04452.9 GAK67160.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Ribosomal_60s PF00428.14 GAK67160.1 - 4.1 7.8 8.7 0.24 11.8 1.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chitin_bind_3 PF03067.10 GAK67161.1 - 3e-46 157.9 0.8 3e-46 157.9 0.6 1.6 2 0 0 2 2 2 1 Chitin binding domain Tmemb_cc2 PF10267.4 GAK67161.1 - 0.55 8.7 6.5 0.69 8.4 4.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Hamartin PF04388.7 GAK67161.1 - 1.7 7.2 12.6 2 6.9 8.8 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.4 GAK67161.1 - 2.8 6.1 12.5 3.4 5.8 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Med3 PF11593.3 GAK67161.1 - 8.7 5.4 19.8 13 4.9 13.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nop25 PF09805.4 GAK67162.1 - 6.5e-24 84.5 14.3 6.5e-24 84.5 9.9 3.2 4 0 0 4 4 4 1 Nucleolar protein 12 (25kDa) RRM_6 PF14259.1 GAK67162.1 - 8.3e-05 22.4 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) KR PF08659.5 GAK67162.1 - 0.00019 21.1 0.3 0.0015 18.2 0.0 2.5 2 0 0 2 2 2 1 KR domain RRM_1 PF00076.17 GAK67162.1 - 0.0025 17.4 0.0 0.011 15.3 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_3 PF07859.8 GAK67164.1 - 3.3e-58 196.7 0.2 4.4e-58 196.3 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK67164.1 - 6.9e-08 32.3 0.4 1.2e-07 31.6 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK67164.1 - 6.2e-07 28.8 0.1 1.1e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 GAK67164.1 - 1.6e-06 27.1 0.6 1.9e-05 23.6 0.4 2.0 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 GAK67164.1 - 0.0012 17.5 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Esterase PF00756.15 GAK67164.1 - 0.0081 15.6 0.3 0.38 10.1 0.2 2.2 1 1 0 1 1 1 1 Putative esterase UBN2_3 PF14244.1 GAK67165.1 - 3.7e-16 59.0 0.1 7.2e-16 58.1 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 GAK67165.1 - 4.8e-12 45.7 1.1 7e-12 45.1 0.7 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 GAK67165.1 - 8.8e-07 28.9 0.1 1.7e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein TPR_MLP1_2 PF07926.7 GAK67165.1 - 0.00068 19.3 0.2 0.0047 16.6 0.0 1.9 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Alpha-E PF04168.7 GAK67165.1 - 0.0084 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. UBN2_2 PF14227.1 GAK67165.1 - 0.01 15.3 0.3 0.016 14.7 0.2 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1642 PF07852.6 GAK67165.1 - 0.03 14.6 0.3 0.12 12.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1642) DUF1319 PF07028.6 GAK67165.1 - 0.058 13.5 0.7 5 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Cyt-b5 PF00173.23 GAK67166.1 - 1.2e-18 66.6 0.1 1.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.17 GAK67167.1 - 3.1e-70 237.0 0.0 3.8e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.8 GAK67169.1 - 4e-16 59.4 14.4 4e-16 59.4 10.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1364 PF07102.7 GAK67170.1 - 0.015 15.1 0.7 0.032 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Abhydrolase_4 PF08386.5 GAK67171.1 - 1.8e-16 59.9 0.0 3.6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 GAK67171.1 - 8.1e-09 35.3 0.0 1e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK67171.1 - 6e-07 29.5 2.5 7.2e-06 26.0 1.1 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK67171.1 - 0.022 14.5 0.0 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Parecho_VpG PF06344.6 GAK67171.1 - 0.089 12.7 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 Parechovirus Genome-linked protein Hep_59 PF07052.6 GAK67172.1 - 1.3e-23 83.2 2.9 1.7e-23 82.9 0.3 2.5 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Glutaredoxin PF00462.19 GAK67172.1 - 2.3e-12 46.7 0.0 1.7e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 GAK67172.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK67172.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SBDS_C PF09377.5 GAK67173.1 - 7e-43 145.2 0.1 1.2e-42 144.4 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 GAK67173.1 - 1.2e-32 111.5 1.3 3.2e-32 110.1 0.4 1.9 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 GAK67173.1 - 0.12 12.1 0.6 0.36 10.5 0.1 2.2 2 1 0 2 2 2 0 Phage XkdN-like protein PMT PF02366.13 GAK67174.1 - 5.6e-76 255.1 17.1 9.2e-76 254.4 11.8 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAK67174.1 - 4.7e-21 75.2 0.3 8.6e-21 74.3 0.2 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 GAK67174.1 - 7e-06 26.0 13.4 7e-06 26.0 9.3 3.0 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 GAK67175.1 - 1.6e-58 192.6 8.5 2.6e-10 39.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 GAK67175.1 - 1.1e-12 46.9 6.5 2e-12 46.1 4.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 GAK67175.1 - 0.00055 18.2 3.5 0.12 10.4 0.5 3.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 GAK67175.1 - 0.013 14.6 0.1 0.45 9.5 0.0 3.1 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Bestrophin PF01062.16 GAK67176.1 - 1.2e-47 162.3 0.8 1.1e-45 155.8 0.6 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Zn_clus PF00172.13 GAK67177.1 - 0.00052 19.8 6.6 0.00096 19.0 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.19 GAK67178.1 - 1.1e-17 63.2 33.3 4.4e-05 23.0 0.5 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 GAK67178.1 - 1.2e-05 25.0 4.0 1.2e-05 24.9 0.9 2.7 2 0 0 2 2 2 1 Zinc knuckle Ribosomal_L24e PF01246.15 GAK67179.1 - 4.8e-29 100.0 3.0 1.1e-28 98.8 2.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Myb_DNA-bind_5 PF13873.1 GAK67180.1 - 0.095 12.6 1.1 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Amino_oxidase PF01593.19 GAK67181.1 - 1.9e-59 201.9 0.0 2.4e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAK67181.1 - 2.2e-13 50.0 0.1 5e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK67181.1 - 1.2e-07 31.0 2.8 3.6e-06 26.1 1.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK67181.1 - 5.1e-06 25.5 0.8 1e-05 24.5 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAK67181.1 - 1.2e-05 23.9 0.1 0.0001 20.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAK67181.1 - 1.5e-05 24.2 0.4 3e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAK67181.1 - 2e-05 24.8 0.2 5.7e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK67181.1 - 5.5e-05 23.3 0.3 0.00058 19.9 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAK67181.1 - 0.00023 20.3 0.1 0.0004 19.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAK67181.1 - 0.0003 19.9 0.9 0.00053 19.1 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 GAK67181.1 - 0.00087 18.2 0.4 0.018 13.9 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAK67181.1 - 0.0033 17.3 0.1 0.0083 16.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK67181.1 - 0.005 15.7 0.4 0.015 14.2 0.4 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAK67181.1 - 0.033 13.9 0.3 0.46 10.2 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding ECR1_N PF14382.1 GAK67181.1 - 0.034 13.4 0.0 0.076 12.3 0.0 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region GDI PF00996.13 GAK67181.1 - 0.28 9.4 0.1 0.49 8.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_binding_4 PF07993.7 GAK67182.1 - 1.9e-30 105.6 0.0 2.7e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAK67182.1 - 0.0003 20.3 0.1 0.0005 19.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAK67182.1 - 0.017 15.3 0.1 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAK67182.1 - 0.075 11.7 0.1 0.3 9.7 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 GAK67183.1 - 8.8e-35 120.0 43.7 2.6e-34 118.4 30.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK67183.1 - 8.6e-13 47.6 8.6 8.6e-13 47.6 5.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAK67183.1 - 8e-08 30.9 18.5 1.5e-07 30.0 12.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nramp PF01566.13 GAK67184.1 - 1.8e-91 306.6 12.1 7.3e-51 173.0 0.6 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein DUF1996 PF09362.5 GAK67185.1 - 2.3e-67 227.0 0.1 2.3e-67 227.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Mucin PF01456.12 GAK67185.1 - 0.94 9.2 22.2 5.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Zn_clus PF00172.13 GAK67186.1 - 0.0044 16.8 6.5 0.0077 16.1 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 GAK67187.1 - 2e-49 163.7 29.8 1.3e-11 43.8 0.2 9.5 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.2 GAK67187.1 - 1e-10 41.1 0.6 2.8e-10 39.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 GAK67187.1 - 3.1e-09 35.5 7.8 0.075 11.1 0.0 5.2 3 1 2 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 GAK67187.1 - 8.3e-05 22.1 1.3 0.00018 21.0 0.9 1.6 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 GAK67187.1 - 3 8.2 12.4 26 5.2 0.0 5.7 5 2 2 7 7 7 0 PQQ-like domain PseudoU_synth_1 PF01416.15 GAK67188.1 - 1.1e-17 64.4 0.0 1.4e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase EF-1_beta_acid PF10587.4 GAK67188.1 - 1.7 8.8 11.4 0.93 9.6 3.1 2.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region TPR_11 PF13414.1 GAK67189.1 - 5.9e-45 150.7 18.8 2.7e-16 58.9 0.3 5.4 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 GAK67189.1 - 7e-32 107.7 10.7 5.9e-06 25.6 0.1 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAK67189.1 - 8.8e-30 100.2 18.0 1.8e-05 24.3 0.0 8.5 9 0 0 9 9 8 6 Tetratricopeptide repeat DnaJ PF00226.26 GAK67189.1 - 1.2e-22 79.3 3.6 2.9e-22 78.1 2.5 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 GAK67189.1 - 8.6e-18 64.4 25.0 2.1e-06 27.9 0.8 6.5 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAK67189.1 - 1.2e-17 62.7 22.6 8.2e-05 22.9 0.4 7.9 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAK67189.1 - 9e-16 57.5 24.1 7.1e-05 22.6 2.0 6.0 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 GAK67189.1 - 3.4e-15 54.5 1.5 0.074 12.8 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAK67189.1 - 8.5e-14 51.7 31.2 6.2e-06 26.7 0.8 5.9 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAK67189.1 - 4.4e-12 45.1 5.9 0.013 15.6 0.0 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAK67189.1 - 4.9e-11 41.5 6.3 0.14 12.0 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAK67189.1 - 2.5e-10 40.0 20.9 4.2e-05 23.3 1.4 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 GAK67189.1 - 6.4e-09 35.8 10.1 0.00013 22.0 0.1 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAK67189.1 - 3.4e-07 30.2 7.1 1.3 9.6 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAK67189.1 - 0.0032 17.7 11.5 0.21 12.1 0.2 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAK67189.1 - 0.014 14.6 1.9 0.077 12.2 0.1 2.7 2 0 0 2 2 2 0 SHNi-TPR BTAD PF03704.12 GAK67189.1 - 0.015 15.6 25.3 0.03 14.6 7.9 4.8 3 2 0 3 3 3 0 Bacterial transcriptional activator domain Coatomer_E PF04733.9 GAK67189.1 - 0.089 11.9 0.1 0.089 11.9 0.1 3.8 3 1 2 5 5 5 0 Coatomer epsilon subunit DUF3856 PF12968.2 GAK67189.1 - 0.1 12.3 14.3 0.039 13.7 4.2 3.7 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 GAK67189.1 - 1.1 9.1 0.0 1.1 9.1 0.0 4.6 4 2 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat DUF982 PF06169.7 GAK67189.1 - 4.3 7.1 10.0 13 5.6 0.2 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF982) AP_endonuc_2 PF01261.19 GAK67190.1 - 4.5e-21 75.1 0.0 5.7e-20 71.5 0.0 2.2 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.6 GAK67191.1 - 2.8e-09 36.8 0.0 6.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAK67191.1 - 3.8e-09 36.7 0.0 8.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 GAK67192.1 - 1.7e-114 382.8 21.9 2e-114 382.6 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK67192.1 - 3.9e-29 101.4 27.1 3.9e-29 101.4 18.8 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Plus-3 PF03126.13 GAK67193.1 - 3.7e-13 49.4 0.0 7.5e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Beta-lactamase PF00144.19 GAK67193.1 - 0.41 9.6 6.8 0.045 12.7 0.6 2.3 3 0 0 3 3 3 0 Beta-lactamase Ebola_NP PF05505.7 GAK67195.1 - 0.085 10.9 0.0 0.094 10.7 0.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein PGA2 PF07543.7 GAK67195.1 - 3.3 7.4 4.8 34 4.2 3.5 2.1 1 1 0 1 1 1 0 Protein trafficking PGA2 MarR_2 PF12802.2 GAK67196.1 - 0.061 13.0 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 MarR family UCH PF00443.24 GAK67198.1 - 3.3e-67 226.4 0.0 5.4e-67 225.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK67198.1 - 1.4e-23 83.8 0.0 2.1e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 GAK67198.1 - 1.6e-06 28.0 0.3 3.6e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.15 GAK67198.1 - 0.00031 21.0 0.0 0.0014 19.0 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain DivIVA PF05103.8 GAK67198.1 - 0.019 14.9 2.2 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein zf-MIZ PF02891.15 GAK67198.1 - 0.056 12.9 0.6 0.11 11.9 0.4 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Aldedh PF00171.17 GAK67199.1 - 5.9e-161 535.8 0.0 6.7e-161 535.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK67199.1 - 0.0052 15.5 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Polysacc_deac_1 PF01522.16 GAK67200.1 - 2e-19 69.4 0.0 3.3e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 GAK67200.1 - 0.013 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 GAK67200.1 - 0.027 12.5 0.0 0.042 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) PX PF00787.19 GAK67201.1 - 5.5e-13 48.6 0.0 9.9e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 GAK67201.1 - 2.9e-11 42.8 4.6 4.9e-11 42.1 3.2 1.3 1 0 0 1 1 1 1 SNARE domain HrpB7 PF09486.5 GAK67201.1 - 0.032 14.1 1.7 0.057 13.3 1.2 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.7 GAK67201.1 - 2.9 8.2 6.5 1.8 8.8 1.8 2.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Actin PF00022.14 GAK67202.1 - 1.4e-116 389.2 0.0 1.7e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAK67202.1 - 0.017 13.7 0.0 0.061 11.9 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein Sec34 PF04136.10 GAK67203.1 - 3.3e-14 52.8 0.1 9e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family 4HBT_3 PF13622.1 GAK67204.1 - 0.022 14.5 1.1 0.021 14.5 0.8 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF2782 PF11191.3 GAK67204.1 - 0.15 12.0 0.9 4.4 7.3 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2782) Mito_fiss_reg PF05308.6 GAK67204.1 - 5.1 6.3 8.3 8.5 5.6 5.6 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.14 GAK67204.1 - 6.9 5.8 6.1 9.5 5.4 4.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PCNA_N PF00705.13 GAK67205.1 - 3.6e-48 162.2 2.2 5.2e-48 161.7 1.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 GAK67205.1 - 1.4e-43 147.9 0.6 2.8e-22 78.9 0.1 2.5 2 1 1 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 GAK67205.1 - 8.7e-05 21.7 0.0 0.00014 21.0 0.0 1.4 1 1 0 1 1 1 1 Rad9 DUF4236 PF14020.1 GAK67205.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) WD40 PF00400.27 GAK67206.1 - 3.2e-43 144.0 8.6 3e-07 30.0 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 GAK67206.1 - 4.7e-11 42.7 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.1 GAK67206.1 - 0.065 13.0 0.0 29 4.4 0.0 3.9 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region DUF3639 PF12341.3 GAK67206.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) Fungal_trans PF04082.13 GAK67207.1 - 1.1e-10 40.8 0.2 2.1e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK67207.1 - 0.00018 21.3 7.0 0.00031 20.5 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RCC1_2 PF13540.1 GAK67208.1 - 1.4e-12 46.8 18.0 9.9e-05 21.8 0.0 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 GAK67208.1 - 1.5e-09 37.8 7.2 1.5 9.0 0.0 6.8 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.28 GAK67208.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 GAK67208.1 - 0.075 12.7 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like Elongin_A PF06881.6 GAK67208.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MFS_1 PF07690.11 GAK67210.1 - 8.4e-30 103.6 22.3 2.3e-29 102.2 15.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK67210.1 - 2.1e-28 99.1 21.2 7.3e-27 94.0 14.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Polyketide_cyc PF03364.15 GAK67211.1 - 9.7e-27 93.5 0.1 1.6e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 GAK67211.1 - 1.6e-08 34.7 0.4 4e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Epimerase PF01370.16 GAK67211.1 - 1.2e-06 28.1 0.0 1.4e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAK67211.1 - 0.00032 20.6 0.0 0.0008 19.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAK67211.1 - 0.00062 19.8 0.1 0.0027 17.7 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding MFS_1 PF07690.11 GAK67212.1 - 2.3e-34 118.6 38.3 2.4e-34 118.5 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex2_Pex12 PF04757.9 GAK67212.1 - 0.01 15.2 0.5 0.01 15.2 0.3 1.5 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region RRM_1 PF00076.17 GAK67213.1 - 1.6e-08 34.0 0.2 0.00065 19.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK67213.1 - 8.8e-07 28.8 0.6 0.033 14.1 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4448 PF14610.1 GAK67214.1 - 5e-16 58.7 0.0 7.9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4083 PF13314.1 GAK67214.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Tim17 PF02466.14 GAK67215.1 - 5.2e-23 81.4 0.1 1.2e-22 80.2 0.0 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Phage_Coat_Gp8 PF05371.7 GAK67216.1 - 0.043 13.3 0.7 0.11 12.1 0.5 1.7 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Apt1 PF10351.4 GAK67216.1 - 0.19 10.5 16.1 0.27 10.0 11.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain AUX_IAA PF02309.11 GAK67216.1 - 0.47 10.1 5.4 0.97 9.1 3.8 1.4 1 0 0 1 1 1 0 AUX/IAA family Podoplanin PF05808.6 GAK67216.1 - 9.1 5.8 27.5 0.62 9.6 13.9 2.3 1 1 1 2 2 2 0 Podoplanin Ribosomal_L28e PF01778.12 GAK67217.1 - 5.5e-31 107.4 0.7 5.5e-31 107.4 0.5 2.2 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 GAK67217.1 - 2.6e-21 75.6 19.1 2.6e-21 75.6 13.2 3.0 1 1 2 3 3 3 1 Mak16 protein C-terminal region CENP-T PF15511.1 GAK67217.1 - 0.0081 15.4 15.9 0.011 15.0 11.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T SGT1 PF07093.6 GAK67217.1 - 0.014 13.8 16.3 0.021 13.2 11.3 1.4 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.7 GAK67217.1 - 0.029 12.3 27.7 0.039 11.8 19.2 1.2 1 0 0 1 1 1 0 Nop14-like family PYC_OADA PF02436.13 GAK67217.1 - 0.073 12.4 0.7 0.13 11.6 0.5 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain CDC45 PF02724.9 GAK67217.1 - 0.47 8.4 17.3 0.88 7.5 12.0 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 GAK67217.1 - 0.56 9.2 32.2 1 8.3 22.3 1.3 1 1 0 1 1 1 0 BUD22 G-alpha PF00503.15 GAK67219.1 - 2.2e-92 309.7 0.0 2.7e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAK67219.1 - 1.4e-11 43.9 0.0 3.8e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.22 GAK67219.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 GAK67219.1 - 0.0015 18.6 0.0 0.0055 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAK67219.1 - 0.0033 17.0 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 GAK67219.1 - 0.0056 16.2 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 GAK67219.1 - 0.011 15.1 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 GAK67219.1 - 0.026 13.9 0.0 0.64 9.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 GAK67219.1 - 0.033 13.9 0.0 0.16 11.7 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain Gtr1_RagA PF04670.7 GAK67219.1 - 0.06 12.4 0.0 8.5 5.4 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 GAK67219.1 - 0.13 12.7 0.0 0.48 10.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein DUF3317 PF11779.3 GAK67220.1 - 0.026 13.9 0.5 0.036 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) DUF4006 PF13179.1 GAK67220.1 - 0.19 11.3 2.4 0.28 10.7 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) START PF01852.14 GAK67221.1 - 6.3e-17 61.5 0.4 1.1e-07 31.4 0.1 3.5 3 0 0 3 3 3 3 START domain DUF3405 PF11885.3 GAK67222.1 - 8.2e-156 519.1 1.7 4.8e-94 315.3 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) R3H-assoc PF13902.1 GAK67223.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 R3H-associated N-terminal domain Vezatin PF12632.2 GAK67224.1 - 5.6e-12 45.2 0.1 6e-06 25.5 0.1 3.4 3 0 0 3 3 3 3 Mysoin-binding motif of peroxisomes Ribosomal_L21p PF00829.16 GAK67225.1 - 1.5e-13 50.6 1.4 3.3e-06 27.1 0.5 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein ATP-synt_ab PF00006.20 GAK67226.1 - 1.1e-69 234.2 0.0 1.6e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAK67226.1 - 2e-23 82.9 0.1 6.2e-23 81.4 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAK67226.1 - 3.7e-20 71.8 2.0 9.9e-20 70.5 1.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 GAK67226.1 - 2.1e-05 24.3 1.1 4.8e-05 23.1 0.8 1.7 1 0 0 1 1 1 1 HAS barrel domain Dynamin_M PF01031.15 GAK67227.1 - 8.2e-114 379.3 0.0 1.2e-113 378.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 GAK67227.1 - 2.9e-54 183.3 0.0 7.7e-54 182.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 GAK67227.1 - 3.8e-29 100.4 1.6 5.2e-29 99.9 0.4 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAK67227.1 - 0.0027 17.6 0.1 0.036 14.0 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAK67227.1 - 0.0078 16.6 0.3 0.076 13.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 GAK67227.1 - 0.044 12.8 0.1 3.2 6.7 0.0 2.5 2 0 0 2 2 2 0 AIG1 family AATase PF07247.7 GAK67228.1 - 2.5e-11 42.8 0.0 4.5e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 GAK67228.1 - 0.012 14.4 0.0 0.043 12.6 0.0 1.8 2 0 0 2 2 2 0 Condensation domain Sds3 PF08598.6 GAK67229.1 - 4.3e-27 94.9 3.4 9.2e-27 93.9 2.3 1.6 1 0 0 1 1 1 1 Sds3-like Flavodoxin_1 PF00258.20 GAK67230.1 - 9.9e-30 103.4 0.0 1.8e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 GAK67230.1 - 4.9e-25 88.2 0.0 1.9e-24 86.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAK67230.1 - 9.5e-13 48.6 0.0 1.6e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 GAK67230.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 GAK67230.1 - 0.045 13.1 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain HTH_43 PF09904.4 GAK67230.1 - 0.079 12.7 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Cas_APE2256 PF09651.5 GAK67230.1 - 0.2 11.3 0.0 0.74 9.5 0.0 1.9 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_APE2256) DUF1752 PF08550.5 GAK67232.1 - 6e-12 44.9 2.7 1.2e-11 43.9 1.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cellulase PF00150.13 GAK67234.1 - 7.4e-08 31.9 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Herpes_US9 PF06072.6 GAK67234.1 - 0.093 12.5 0.7 0.18 11.6 0.5 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 TPPK_C PF12555.3 GAK67234.1 - 0.5 10.1 5.4 0.091 12.5 1.1 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Zw10 PF06248.8 GAK67235.1 - 2.3e-14 52.4 0.1 1e-13 50.3 0.0 1.9 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 GAK67235.1 - 0.044 12.9 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal DegV PF02645.11 GAK67236.1 - 0.01 14.9 0.2 0.01 14.9 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 BBP1_C PF15272.1 GAK67236.1 - 0.11 12.0 1.2 0.19 11.2 0.8 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Myosin_HC-like PF07058.6 GAK67236.1 - 0.19 10.7 9.3 0.013 14.6 1.8 2.0 2 0 0 2 2 2 0 Myosin II heavy chain-like AATF-Che1 PF13339.1 GAK67236.1 - 1.5 9.0 5.8 0.2 11.8 0.4 2.2 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Ctr PF04145.10 GAK67237.1 - 2.7e-37 128.0 1.1 2.7e-37 128.0 0.8 2.6 2 0 0 2 2 2 1 Ctr copper transporter family VPS9 PF02204.13 GAK67237.1 - 3e-30 104.2 0.2 6.4e-30 103.2 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 GAK67237.1 - 2.6e-13 49.1 0.2 5.4e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 CUE domain LisH PF08513.6 GAK67238.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 LisH WD40 PF00400.27 GAK67241.1 - 4.4e-13 48.5 0.9 1 9.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat FF PF01846.14 GAK67242.1 - 4.3e-27 93.8 11.7 9.7e-10 38.2 0.0 5.8 6 0 0 6 6 6 4 FF domain WW PF00397.21 GAK67242.1 - 3.7e-11 42.6 11.9 8.2e-06 25.5 1.0 2.6 2 0 0 2 2 2 2 WW domain Creatininase PF02633.9 GAK67242.1 - 0.0068 15.5 1.7 0.012 14.7 0.6 1.9 2 0 0 2 2 2 1 Creatinine amidohydrolase U3_snoRNA_assoc PF08297.6 GAK67242.1 - 0.82 9.9 0.0 0.82 9.9 0.0 3.7 4 0 0 4 4 4 0 U3 snoRNA associated RRM_1 PF00076.17 GAK67243.1 - 8.4e-30 102.2 0.1 2.1e-15 56.0 0.0 5.1 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK67243.1 - 3.9e-18 65.2 0.0 1.1e-05 25.3 0.0 4.5 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK67243.1 - 7.7e-13 48.0 0.0 0.00087 19.1 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AIRS PF00586.19 GAK67243.1 - 0.014 15.5 0.1 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain HMG_CoA_synt_N PF01154.12 GAK67244.1 - 9.1e-86 285.8 0.1 1.8e-85 284.8 0.1 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 GAK67244.1 - 7.4e-84 281.5 0.1 9.7e-84 281.1 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.5 GAK67244.1 - 0.0023 17.9 0.0 0.026 14.5 0.0 2.5 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 GAK67244.1 - 0.025 14.2 0.4 0.077 12.6 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cu-oxidase_3 PF07732.10 GAK67245.1 - 2.3e-34 117.6 0.3 5.3e-34 116.4 0.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAK67245.1 - 1.8e-28 98.7 8.1 3.5e-23 81.6 0.5 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAK67245.1 - 3.2e-16 59.6 0.0 4.3e-12 46.2 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Amidase PF01425.16 GAK67246.1 - 2.1e-95 320.2 0.0 2.5e-95 319.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 GAK67247.1 - 7.2e-44 149.8 0.0 1.1e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67247.1 - 9.8e-15 54.3 0.0 1.8e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAK67247.1 - 0.00011 21.5 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 GAK67247.1 - 0.071 12.6 0.3 0.41 10.2 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase TPR_11 PF13414.1 GAK67248.1 - 4.3e-27 93.5 2.1 1e-17 63.5 1.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAK67248.1 - 3e-24 83.5 0.2 7.7e-09 34.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAK67248.1 - 3.9e-18 63.8 0.1 5.7e-07 28.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAK67248.1 - 2.8e-13 50.1 2.5 2.8e-06 27.8 0.1 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat Abhydrolase_2 PF02230.11 GAK67248.1 - 5e-13 48.9 0.0 1.1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase TPR_14 PF13428.1 GAK67248.1 - 7.9e-12 44.6 0.4 3.1e-05 24.2 0.0 4.5 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAK67248.1 - 2.5e-11 42.4 0.1 0.00041 19.9 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAK67248.1 - 1.1e-10 40.7 0.0 6.7e-05 22.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAK67248.1 - 8e-10 37.7 0.0 7.9e-06 25.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAK67248.1 - 1.9e-08 34.5 2.5 6.9e-05 23.1 0.0 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAK67248.1 - 1.9e-07 30.8 0.3 5.8e-06 26.1 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 GAK67248.1 - 3e-05 24.3 0.1 0.0046 17.2 0.0 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 GAK67248.1 - 0.00018 21.2 0.0 0.054 13.3 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAK67248.1 - 0.00023 21.4 1.5 2.9 8.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 GAK67248.1 - 0.0021 18.1 0.7 0.015 15.4 0.0 2.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAK67248.1 - 0.0035 16.4 1.0 0.0089 15.1 0.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAK67248.1 - 0.012 15.5 0.0 0.65 10.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat XPC-binding PF09280.6 GAK67248.1 - 0.076 12.4 8.6 0.053 12.9 3.4 2.4 2 0 0 2 2 2 0 XPC-binding domain HRDC PF00570.18 GAK67248.1 - 0.27 10.9 0.9 2 8.1 0.1 2.6 2 0 0 2 2 2 0 HRDC domain DHHA1 PF02272.14 GAK67248.1 - 2.9 7.6 9.3 1.3 8.8 0.0 3.1 2 1 1 3 3 3 0 DHHA1 domain MIT PF04212.13 GAK67248.1 - 5.4 6.9 10.3 1.4 8.8 0.2 3.0 3 1 0 3 3 2 0 MIT (microtubule interacting and transport) domain RNase_H2_suC PF08615.6 GAK67249.1 - 7.1e-24 84.2 0.0 1.4e-23 83.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CDC45 PF02724.9 GAK67249.1 - 0.014 13.4 3.1 0.017 13.1 2.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 GAK67249.1 - 0.084 11.7 3.2 0.11 11.3 2.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SAPS PF04499.10 GAK67249.1 - 0.31 9.6 3.8 0.42 9.1 2.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SAGA-Tad1 PF12767.2 GAK67249.1 - 0.47 10.0 5.3 0.71 9.4 3.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ebola_NP PF05505.7 GAK67249.1 - 1.2 7.1 6.8 1.4 6.8 4.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Hid1 PF12722.2 GAK67249.1 - 4.2 4.9 5.7 5 4.6 3.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1675 PF07897.6 GAK67249.1 - 4.6 7.0 10.1 0.16 11.7 2.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) HSP70 PF00012.15 GAK67250.1 - 5.7e-76 255.7 0.1 8.8e-76 255.0 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAK67250.1 - 8.3e-07 27.9 0.3 2.8e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 GAK67250.1 - 0.00058 19.0 0.3 0.0019 17.3 0.1 1.9 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase Actin PF00022.14 GAK67250.1 - 0.011 14.1 0.2 0.78 8.1 0.0 2.1 1 1 1 2 2 2 0 Actin PilM_2 PF11104.3 GAK67250.1 - 0.029 13.2 0.0 0.63 8.8 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; MBOAT PF03062.14 GAK67252.1 - 1.2e-35 123.1 3.9 1.2e-35 123.1 2.7 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 GAK67252.1 - 0.00061 19.8 3.8 0.0023 17.9 2.6 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Methyltransf_23 PF13489.1 GAK67253.1 - 2.5e-14 53.3 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK67253.1 - 2.6e-14 53.4 0.0 4.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK67253.1 - 4.2e-14 52.4 0.0 8e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK67253.1 - 9.3e-14 51.9 0.0 1.5e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK67253.1 - 1.9e-13 50.7 0.1 2.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAK67253.1 - 5.5e-07 29.1 0.0 8.6e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 GAK67253.1 - 2.6e-06 27.0 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAK67253.1 - 5.3e-06 26.4 0.0 1.1e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK67253.1 - 2.5e-05 23.5 0.0 0.00012 21.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 GAK67253.1 - 2.5e-05 23.4 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 GAK67253.1 - 9.5e-05 21.6 0.1 0.00018 20.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 GAK67253.1 - 0.00019 20.2 0.0 0.00026 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 GAK67253.1 - 0.00021 21.5 0.0 0.00033 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 GAK67253.1 - 0.0013 17.4 0.0 0.0022 16.7 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase FmrO PF07091.6 GAK67253.1 - 0.0021 17.0 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) NodS PF05401.6 GAK67253.1 - 0.0078 15.6 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 GAK67253.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 GAK67253.1 - 0.014 14.4 0.0 0.054 12.5 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase TehB PF03848.9 GAK67253.1 - 0.065 12.4 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.7 GAK67253.1 - 0.076 11.8 0.0 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase DUF640 PF04852.7 GAK67254.1 - 0.013 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF640) N-SET PF11764.3 GAK67254.1 - 0.042 13.7 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N TPR_12 PF13424.1 GAK67254.1 - 0.054 13.4 0.5 2.3 8.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.15 GAK67255.1 - 1.9e-26 91.7 0.2 6.9e-26 89.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 GAK67255.1 - 2.1e-07 31.1 0.5 2.1e-07 31.1 0.3 3.3 3 2 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAK67255.1 - 2.7e-05 24.1 0.1 0.00036 20.5 0.0 2.8 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 GAK67255.1 - 0.00011 22.2 0.4 0.00034 20.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 GAK67255.1 - 0.033 13.7 0.1 0.033 13.7 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin DUF4451 PF14616.1 GAK67256.1 - 2.3e-29 101.6 2.8 4.7e-29 100.6 1.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Lactamase_B_2 PF12706.2 GAK67260.1 - 1.3e-35 122.7 0.1 1.8e-35 122.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAK67260.1 - 3.9e-15 55.9 0.0 6.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAK67260.1 - 0.0015 18.2 0.0 0.0095 15.6 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Prenyltrans PF00432.16 GAK67261.1 - 6e-31 105.6 10.2 3.2e-07 29.7 0.0 6.4 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAK67261.1 - 4.4e-18 65.7 0.4 2.9e-15 56.6 0.0 3.2 3 0 0 3 3 3 2 Prenyltransferase-like Amidohydro_4 PF13147.1 GAK67262.1 - 1.1e-31 110.9 3.7 1.1e-31 110.9 2.6 2.8 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 GAK67262.1 - 2.2e-17 62.6 0.7 1.9e-12 46.8 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 GAK67262.1 - 1e-06 28.6 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family UNC-93 PF05978.11 GAK67263.1 - 9.4e-12 44.6 10.7 2.9e-11 43.1 6.3 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 GAK67263.1 - 1.1e-10 40.7 35.8 1.1e-10 40.7 24.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-CCCH PF00642.19 GAK67264.1 - 9.5e-14 50.6 24.2 5.8e-06 25.8 1.7 4.6 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAK67264.1 - 5.4 7.1 10.9 11 6.2 0.6 3.3 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF2235 PF09994.4 GAK67265.1 - 6e-58 196.4 0.0 7.9e-57 192.7 0.0 2.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2919 PF11143.3 GAK67267.1 - 0.66 9.8 4.5 1 9.1 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2919) RhoGAP PF00620.22 GAK67268.1 - 3e-37 127.5 0.1 6.3e-37 126.5 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 GAK67268.1 - 6.2e-27 93.4 33.7 2.5e-11 43.4 2.4 5.0 5 0 0 5 5 5 4 LIM domain SH3_9 PF14604.1 GAK67269.1 - 2.5e-28 97.4 1.0 2.1e-14 52.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAK67269.1 - 5.1e-24 83.3 1.9 1.1e-12 47.1 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAK67269.1 - 2.4e-16 58.9 0.3 6.4e-08 31.9 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 GAK67269.1 - 1e-13 51.2 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein His_Phos_1 PF00300.17 GAK67270.1 - 2.5e-40 138.1 0.0 2.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sortase PF04203.8 GAK67270.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Sortase family Ank_4 PF13637.1 GAK67271.1 - 3.9e-10 39.9 2.3 0.00042 20.7 0.4 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAK67271.1 - 1.6e-09 37.9 2.6 0.00034 20.9 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAK67271.1 - 1e-07 31.4 3.7 0.0079 15.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 GAK67271.1 - 3.4e-06 26.7 2.5 0.026 14.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAK67271.1 - 1.1e-05 25.4 4.1 0.014 15.6 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.8 GAK67271.1 - 1.3e-05 24.8 0.3 0.0001 21.8 0.2 2.1 1 1 0 1 1 1 1 KilA-N domain Fib_alpha PF08702.5 GAK67271.1 - 0.15 12.1 4.3 4.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.7 GAK67271.1 - 1.8 8.5 4.3 1 9.3 0.4 2.4 2 0 0 2 2 2 0 MbeD/MobD like SH3_1 PF00018.23 GAK67272.1 - 1.4e-38 130.0 9.0 3.6e-15 55.0 0.1 4.6 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 GAK67272.1 - 1.6e-37 126.8 12.3 5.6e-13 48.2 0.1 4.8 4 1 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 GAK67272.1 - 1e-31 108.3 0.0 1.9e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 GAK67272.1 - 1.4e-26 91.7 0.0 1.2e-07 31.1 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 GAK67272.1 - 0.00028 21.0 2.5 0.034 14.3 0.1 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain Rtf2 PF04641.7 GAK67273.1 - 2.1e-70 236.9 1.5 2.3e-70 236.7 1.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 GAK67273.1 - 0.00052 19.4 0.4 0.03 13.8 0.0 2.9 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 GAK67273.1 - 0.0034 17.2 2.8 0.0038 17.0 0.9 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 GAK67273.1 - 0.0055 16.2 1.4 0.0098 15.4 1.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 GAK67273.1 - 0.012 15.2 2.6 0.022 14.4 1.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK67273.1 - 0.016 15.0 2.9 0.03 14.1 2.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 GAK67273.1 - 0.075 12.7 2.6 0.13 11.9 1.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 GAK67273.1 - 0.38 10.2 2.5 0.64 9.5 0.9 1.9 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF2072 PF09845.4 GAK67273.1 - 0.62 10.0 4.7 1.1 9.1 3.3 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) SHS2_Rpb7-N PF03876.12 GAK67274.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 GAK67274.1 - 2.3e-09 37.1 0.3 7.5e-09 35.5 0.2 1.8 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 GAK67274.1 - 0.034 14.3 0.1 0.066 13.4 0.1 1.6 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Ribonuc_P_40 PF08584.6 GAK67275.1 - 3.3e-23 82.0 0.0 2.5e-21 75.9 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit zf-RING_2 PF13639.1 GAK67276.1 - 7.9e-12 44.8 1.4 1.5e-11 43.9 1.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAK67276.1 - 8.3e-09 35.3 1.3 1.5e-08 34.5 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK67276.1 - 5.4e-07 29.1 0.6 9.8e-07 28.3 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK67276.1 - 7.5e-07 28.7 0.7 1.3e-06 28.0 0.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 GAK67276.1 - 2.9e-06 27.2 0.7 6.1e-06 26.2 0.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAK67276.1 - 5.6e-05 22.7 0.4 9.5e-05 21.9 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 GAK67276.1 - 0.001 18.9 0.9 0.0022 17.8 0.6 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 GAK67276.1 - 0.0033 17.0 0.1 0.0076 15.9 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Reo_sigmaC PF04582.7 GAK67276.1 - 0.0077 15.4 2.8 0.0077 15.4 1.9 2.0 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Fib_alpha PF08702.5 GAK67276.1 - 0.055 13.5 11.3 0.062 13.4 6.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-Apc11 PF12861.2 GAK67276.1 - 0.16 11.8 0.2 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 GAK67276.1 - 0.18 11.6 1.1 0.57 10.0 0.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 GAK67276.1 - 0.19 11.8 0.6 0.5 10.4 0.4 1.8 1 0 0 1 1 1 0 RING-variant domain Lectin_N PF03954.9 GAK67276.1 - 0.44 9.9 9.4 0.31 10.4 2.6 2.6 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Spc7 PF08317.6 GAK67276.1 - 0.52 8.9 15.7 0.25 9.9 9.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein SYS1 PF09801.4 GAK67277.1 - 2.1e-23 82.9 6.1 2.3e-17 63.3 2.0 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network FMO-like PF00743.14 GAK67279.1 - 1.3e-34 119.3 0.0 5.9e-12 44.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAK67279.1 - 3.7e-20 72.8 0.0 1.5e-17 64.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK67279.1 - 2.3e-06 27.5 0.0 6e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAK67279.1 - 4.3e-06 26.5 0.0 2.9e-05 23.8 0.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAK67279.1 - 5.7e-06 25.4 0.0 0.077 11.8 0.0 3.8 3 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 GAK67279.1 - 0.00031 20.8 0.2 0.014 15.5 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 GAK67279.1 - 0.00035 20.5 0.0 1.7 8.4 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK67279.1 - 0.0011 19.3 0.3 0.45 10.9 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK67279.1 - 0.0056 15.8 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Thi4 family NAD_binding_7 PF13241.1 GAK67279.1 - 0.026 14.7 0.1 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 GAK67280.1 - 4.9e-10 39.2 0.0 1.4e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAK67280.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAK67280.1 - 0.0011 18.8 0.0 0.6 9.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK67280.1 - 0.0029 16.1 0.1 0.0083 14.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAK67280.1 - 0.0033 17.5 0.0 0.076 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAK67280.1 - 0.0045 15.9 0.2 0.014 14.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAK67280.1 - 0.075 12.8 1.2 0.24 11.1 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 GAK67280.1 - 0.077 12.5 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 GAK67280.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain SET PF00856.23 GAK67282.1 - 1.7e-23 83.6 0.3 1.8e-22 80.3 0.2 2.4 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 GAK67282.1 - 1.7e-15 57.1 1.4 1.7e-15 57.1 1.0 2.3 2 0 0 2 2 2 1 Pre-SET motif Sec7 PF01369.15 GAK67283.1 - 1.4e-36 125.9 0.0 2.4e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_10 PF15411.1 GAK67283.1 - 0.02 15.0 0.0 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4449 PF14613.1 GAK67284.1 - 3.8e-32 111.4 0.2 3.8e-32 111.4 0.1 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) TPR_6 PF13174.1 GAK67284.1 - 0.42 11.1 2.8 23 5.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BNR PF02012.15 GAK67285.1 - 6.8e-09 34.2 45.1 0.72 9.9 0.0 12.0 11 0 0 11 11 11 6 BNR/Asp-box repeat Fe_dep_repr_C PF02742.10 GAK67285.1 - 0.0012 18.4 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain F5_F8_type_C PF00754.20 GAK67285.1 - 0.0043 16.8 0.9 0.62 9.9 0.0 4.7 5 0 0 5 5 5 1 F5/8 type C domain PSII_BNR PF14870.1 GAK67285.1 - 0.018 14.0 2.9 4.3 6.2 0.0 4.0 4 1 1 5 5 5 0 Photosynthesis system II assembly factor YCF48 SRF-TF PF00319.13 GAK67286.1 - 3.6e-22 77.3 0.0 6.1e-22 76.5 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF2457 PF10446.4 GAK67286.1 - 1.3 7.7 7.2 2.3 6.8 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MS_channel PF00924.13 GAK67288.1 - 1.1e-21 77.1 1.4 1.8e-21 76.4 1.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 GAK67288.1 - 3.3e-06 25.9 0.1 6.7e-06 25.0 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAK67288.1 - 4.7e-05 22.9 0.0 0.00015 21.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 GAK67288.1 - 0.00031 19.9 0.2 0.0007 18.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAK67288.1 - 0.00039 20.5 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 GAK67288.1 - 0.002 17.7 0.1 0.0037 16.8 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair Tubulin PF00091.20 GAK67289.1 - 9.6e-62 208.6 0.0 1.5e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAK67289.1 - 1.7e-41 141.2 0.0 2.9e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAK67289.1 - 0.003 17.0 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.1 GAK67289.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Tubulin like KRE9 PF05390.6 GAK67290.1 - 0.053 13.8 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 MFS_1 PF07690.11 GAK67292.1 - 1.7e-38 132.2 48.9 1.7e-38 132.2 33.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAK67292.1 - 6.1e-10 37.9 24.7 9e-10 37.3 17.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAK67292.1 - 2e-08 33.2 9.1 2e-08 33.2 6.3 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter UPF0150 PF03681.10 GAK67299.1 - 0.036 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) DUF3921 PF13060.1 GAK67299.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) STT3 PF02516.9 GAK67301.1 - 1.6e-130 436.3 34.9 9.4e-125 417.3 22.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pep3_Vps18 PF05131.9 GAK67302.1 - 1.4e-41 141.3 0.0 3.2e-41 140.1 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 GAK67302.1 - 1.9e-12 47.0 1.9 8.9e-07 28.6 0.0 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.4 GAK67302.1 - 0.00057 20.0 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 GAK67302.1 - 0.0074 16.1 5.4 0.01 15.6 2.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAK67302.1 - 0.052 13.5 3.7 0.046 13.7 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 GAK67302.1 - 0.13 12.3 0.0 0.46 10.5 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3778 PF12620.3 GAK67302.1 - 0.15 11.6 0.0 0.51 9.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) zf-RING_5 PF14634.1 GAK67302.1 - 0.28 10.9 7.3 0.019 14.6 1.4 1.8 2 0 0 2 2 2 0 zinc-RING finger domain MTP18 PF10558.4 GAK67303.1 - 1.8e-61 206.4 0.5 2.6e-61 205.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Glyco_hydro_18 PF00704.23 GAK67304.1 - 0.00011 21.7 0.0 0.0042 16.5 0.0 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 ARL6IP6 PF15062.1 GAK67304.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Pkinase PF00069.20 GAK67305.1 - 1.1e-71 241.0 0.0 1.2e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67305.1 - 1.3e-31 109.6 0.0 1.6e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK67305.1 - 1e-05 24.6 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK67305.1 - 0.0028 17.4 0.0 0.0098 15.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAK67305.1 - 0.0054 15.6 0.0 0.0083 15.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Peptidase_S9_N PF02897.10 GAK67306.1 - 1.6e-84 283.9 3.8 2.2e-84 283.4 2.6 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 GAK67306.1 - 1.7e-52 177.7 0.1 2.7e-52 177.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family SAD_SRA PF02182.12 GAK67307.1 - 1e-47 161.2 0.2 2.1e-47 160.2 0.0 1.6 2 0 0 2 2 2 1 SAD/SRA domain Trypan_PARP PF05887.6 GAK67307.1 - 0.19 11.5 15.6 0.081 12.7 3.6 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Vps5 PF09325.5 GAK67308.1 - 1.2e-65 221.1 6.4 1.2e-65 221.1 4.4 3.2 2 1 1 3 3 3 1 Vps5 C terminal like RmlD_sub_bind PF04321.12 GAK67308.1 - 6.1e-53 179.5 0.0 1.8e-52 178.0 0.0 1.9 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 GAK67308.1 - 1.7e-25 89.8 0.0 3.7e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.19 GAK67308.1 - 4.7e-23 81.1 0.0 9.5e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 PX domain Polysacc_synt_2 PF02719.10 GAK67308.1 - 1e-07 31.1 0.2 4e-06 25.9 0.1 3.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAK67308.1 - 6.6e-06 25.2 0.1 0.00011 21.2 0.0 2.7 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 GAK67308.1 - 0.2 10.3 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SET PF00856.23 GAK67308.1 - 2.5 8.3 7.7 1.4 9.1 1.0 2.9 2 0 0 2 2 2 0 SET domain HAD_2 PF13419.1 GAK67309.1 - 8.3e-16 58.7 0.0 9.6e-11 42.2 0.0 2.3 1 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAK67309.1 - 2.1e-08 34.8 0.0 8.4e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAK67309.1 - 0.0035 17.0 0.2 0.027 14.1 0.1 2.5 3 1 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.2 GAK67309.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAK67309.1 - 0.13 12.2 0.0 19 5.2 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Metallophos PF00149.23 GAK67310.1 - 4.7e-30 104.4 0.0 6.2e-23 81.2 0.1 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TPR_11 PF13414.1 GAK67310.1 - 2.1e-21 75.3 3.2 5.4e-16 57.9 0.5 2.5 1 1 2 3 3 3 3 TPR repeat PPP5 PF08321.7 GAK67310.1 - 7.1e-13 48.3 0.0 1.6e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 GAK67310.1 - 8.2e-12 44.2 3.2 0.0002 20.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAK67310.1 - 1.9e-08 33.6 3.1 0.021 14.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK67310.1 - 3.3e-05 24.4 1.8 0.00018 22.0 0.4 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAK67310.1 - 0.0032 17.5 0.9 2.9 8.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAK67310.1 - 0.033 14.0 0.4 0.25 11.2 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAK67310.1 - 0.041 13.6 0.1 35 4.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat VitD-bind_III PF09164.5 GAK67310.1 - 0.11 12.0 0.2 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III TPR_12 PF13424.1 GAK67310.1 - 0.25 11.3 1.1 0.62 10.0 0.8 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAK67310.1 - 0.61 10.8 2.4 46 5.0 0.0 3.3 2 1 2 4 4 3 0 Tetratricopeptide repeat HMG_box_5 PF14887.1 GAK67311.1 - 0.028 14.1 0.3 0.079 12.7 0.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 BAR PF03114.13 GAK67312.1 - 4.1e-48 163.9 1.0 4.9e-48 163.6 0.7 1.1 1 0 0 1 1 1 1 BAR domain AAA_13 PF13166.1 GAK67312.1 - 0.0013 17.2 1.6 0.0017 16.9 1.1 1.1 1 0 0 1 1 1 1 AAA domain Arfaptin PF06456.8 GAK67312.1 - 0.0038 16.6 2.8 0.008 15.5 2.0 1.8 1 1 0 1 1 1 1 Arfaptin-like domain Laminin_I PF06008.9 GAK67312.1 - 0.019 14.3 0.8 0.019 14.3 0.6 2.2 3 0 0 3 3 3 0 Laminin Domain I HHH_8 PF14716.1 GAK67312.1 - 0.046 13.8 2.9 6.8 6.9 0.1 2.7 1 1 1 2 2 2 0 Helix-hairpin-helix domain TMPIT PF07851.8 GAK67312.1 - 0.052 12.6 1.1 0.13 11.3 0.1 1.8 1 1 1 2 2 2 0 TMPIT-like protein RNase_H PF00075.19 GAK67312.1 - 0.067 13.5 0.1 0.095 13.0 0.1 1.2 1 0 0 1 1 1 0 RNase H Myosin_tail_1 PF01576.14 GAK67312.1 - 0.079 10.6 4.5 0.12 10.0 3.1 1.3 1 1 0 1 1 1 0 Myosin tail DUF746 PF05344.6 GAK67312.1 - 0.097 12.2 0.0 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Laminin_II PF06009.7 GAK67312.1 - 0.21 11.3 1.9 2.1 8.1 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II Vps5 PF09325.5 GAK67312.1 - 0.28 10.4 4.3 1.6 7.9 3.0 2.0 1 1 0 1 1 1 0 Vps5 C terminal like Sec2p PF06428.6 GAK67312.1 - 0.32 10.8 5.0 1.9 8.3 0.5 3.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p GAS PF13851.1 GAK67312.1 - 0.33 10.1 5.0 0.32 10.1 0.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Sigma70_ner PF04546.8 GAK67312.1 - 0.43 10.1 4.6 0.84 9.2 1.6 2.5 1 1 2 3 3 3 0 Sigma-70, non-essential region APG6 PF04111.7 GAK67312.1 - 0.59 9.1 3.7 0.14 11.1 0.3 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 GAK67312.1 - 2.2 8.3 7.0 1.9 8.5 1.0 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Occludin_ELL PF07303.8 GAK67312.1 - 2.5 8.8 5.1 1.8 9.3 0.2 2.8 3 1 0 3 3 3 0 Occludin homology domain DivIC PF04977.10 GAK67312.1 - 3.1 7.3 6.8 0.24 10.9 0.5 2.3 3 0 0 3 3 3 0 Septum formation initiator Snf7 PF03357.16 GAK67313.1 - 3e-49 166.7 14.1 3.5e-49 166.4 9.8 1.0 1 0 0 1 1 1 1 Snf7 NuA4 PF09340.5 GAK67313.1 - 0.0014 18.2 0.8 0.0028 17.2 0.5 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 T4SS PF07996.6 GAK67313.1 - 0.008 16.0 7.7 0.014 15.2 5.3 1.4 1 0 0 1 1 1 1 Type IV secretion system proteins Soyouz_module PF14313.1 GAK67313.1 - 0.029 13.9 0.1 9.5 5.8 0.0 2.8 3 0 0 3 3 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Mod_r PF07200.8 GAK67313.1 - 0.03 14.2 9.5 0.019 14.8 5.0 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 GAK67313.1 - 0.11 12.2 12.2 1.1 8.9 8.4 2.2 1 1 0 1 1 1 0 Mnd1 family Prefoldin PF02996.12 GAK67313.1 - 0.11 12.1 9.8 7 6.3 0.8 3.5 4 0 0 4 4 4 0 Prefoldin subunit Prefoldin_2 PF01920.15 GAK67313.1 - 0.12 12.1 13.3 1.7 8.4 0.0 3.4 2 1 0 2 2 2 0 Prefoldin subunit PEP-utilisers_N PF05524.8 GAK67313.1 - 0.21 11.3 10.0 0.42 10.4 2.4 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal V_ATPase_I PF01496.14 GAK67313.1 - 0.27 9.0 2.9 0.37 8.5 2.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 GAK67313.1 - 0.28 11.0 2.3 29 4.6 0.0 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Hemerythrin PF01814.18 GAK67313.1 - 0.36 10.9 5.7 0.36 10.9 2.0 2.5 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF848 PF05852.6 GAK67313.1 - 0.49 10.2 9.9 0.41 10.4 5.1 2.1 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) FlxA PF14282.1 GAK67313.1 - 0.74 9.7 10.0 1.1 9.2 4.2 2.4 1 1 1 2 2 2 0 FlxA-like protein FoP_duplication PF13865.1 GAK67313.1 - 0.77 10.2 6.5 1.1 9.7 0.1 3.0 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 NPV_P10 PF05531.7 GAK67313.1 - 0.85 9.9 7.4 5.2 7.3 1.2 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Macoilin PF09726.4 GAK67313.1 - 1.1 7.4 7.2 1.4 7.1 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 GAK67313.1 - 1.6 7.6 8.2 2.4 7.0 5.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 GAK67313.1 - 5.9 6.8 18.1 2.9 7.8 1.8 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ssl1 PF04056.9 GAK67314.1 - 7e-68 228.0 0.0 1e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 GAK67314.1 - 1.7e-17 63.1 10.6 1.7e-17 63.1 7.3 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 GAK67314.1 - 6.8e-11 42.5 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tnp_zf-ribbon_2 PF13842.1 GAK67314.1 - 0.86 10.0 18.6 1.5 9.2 3.1 2.9 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Tfb4 PF03850.9 GAK67314.1 - 4.9 6.3 5.4 46 3.1 3.6 2.4 2 1 0 3 3 3 0 Transcription factor Tfb4 Collagen PF01391.13 GAK67315.1 - 1.7e-05 24.2 23.4 1.7e-05 24.2 16.2 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Nop53 PF07767.6 GAK67316.1 - 8e-85 285.1 19.9 9.8e-85 284.8 13.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ank PF00023.25 GAK67317.1 - 3.9e-16 57.9 2.7 2.3e-07 30.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 GAK67317.1 - 4.6e-16 58.9 1.3 5.3e-13 49.1 1.3 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAK67317.1 - 8.3e-16 58.0 4.7 1.7e-11 44.3 0.7 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK67317.1 - 1.2e-14 52.8 1.6 6.3e-06 25.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAK67317.1 - 1.9e-12 46.9 3.8 8.7e-06 25.8 0.1 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Mt_ATP-synt_B PF05405.9 GAK67318.1 - 9.8e-40 135.6 12.3 5.1e-27 94.3 6.3 2.1 2 0 0 2 2 2 2 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Virulence_fact PF13769.1 GAK67318.1 - 0.1 12.5 1.6 0.26 11.1 1.1 1.8 1 0 0 1 1 1 0 Virulence factor Cauli_DNA-bind PF03310.8 GAK67318.1 - 0.15 11.8 3.5 0.15 11.8 1.3 1.8 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein BCDHK_Adom3 PF10436.4 GAK67320.1 - 1.9e-67 225.8 0.0 3.3e-67 225.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAK67320.1 - 5e-19 68.0 0.0 9.9e-19 67.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAK67320.1 - 1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSF_DNA-bind PF00447.12 GAK67321.1 - 3.1e-34 117.2 0.8 4.9e-34 116.6 0.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding TPR_MLP1_2 PF07926.7 GAK67321.1 - 0.1 12.3 0.3 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 GAK67321.1 - 0.26 10.8 0.2 0.59 9.6 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator DPPIV_N PF00930.16 GAK67322.1 - 3.3e-73 246.2 0.0 7.8e-73 245.0 0.0 1.6 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 GAK67322.1 - 2.9e-45 154.1 3.5 4.6e-45 153.4 2.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAK67322.1 - 3.9e-09 36.4 0.9 1e-08 35.0 0.6 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK67322.1 - 2.3e-07 30.9 1.8 2.3e-07 30.9 1.2 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAK67322.1 - 2.9e-06 26.9 4.9 8.3e-06 25.4 2.8 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAK67322.1 - 1.4e-05 23.7 0.0 0.00087 17.8 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 GAK67322.1 - 0.0058 15.9 0.7 0.016 14.5 0.5 1.7 1 0 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.6 GAK67322.1 - 0.072 12.7 0.0 7.3 6.2 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.11 GAK67323.1 - 7.7e-23 80.7 34.9 2.4e-17 62.6 7.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLAC1 PF03595.12 GAK67324.1 - 4.6e-90 301.6 55.9 5.3e-90 301.4 38.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1349 PF07081.6 GAK67325.1 - 1.6e-17 63.4 0.0 2.1e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) E1-E2_ATPase PF00122.15 GAK67326.1 - 1.4e-27 96.2 0.2 2.3e-27 95.5 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 GAK67326.1 - 6.9e-27 93.6 0.1 1.8e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 GAK67326.1 - 5.2e-25 88.7 0.0 9.4e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAK67326.1 - 1.7e-22 80.9 0.0 2.4e-21 77.1 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK67326.1 - 8.4e-06 25.1 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAK67326.1 - 4.1e-05 23.4 0.0 9.9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAK67326.1 - 0.029 13.9 0.0 0.37 10.3 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Glyco_hydro_16 PF00722.16 GAK67326.1 - 0.12 11.6 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 Daxx PF03344.10 GAK67326.1 - 7.6 4.8 10.1 15 3.8 7.0 1.4 1 0 0 1 1 1 0 Daxx Family AA_permease PF00324.16 GAK67327.1 - 3e-96 322.6 43.6 3.4e-96 322.4 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAK67327.1 - 7.7e-27 93.8 48.4 1e-26 93.5 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease RA PF00788.18 GAK67328.1 - 2.1e-18 66.5 0.1 3.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 GAK67328.1 - 2.4e-13 49.2 0.3 3.7e-08 32.6 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SAM_1 PF00536.25 GAK67328.1 - 7.9e-13 48.3 0.0 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAK67328.1 - 9.9e-13 47.7 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 GAK67328.1 - 8.8e-11 41.2 2.7 1.5e-05 24.4 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 GAK67328.1 - 1.1e-08 34.4 1.5 3.5e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain DUF2205 PF10224.4 GAK67329.1 - 0.023 14.2 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) ADH_N PF08240.7 GAK67330.1 - 9.3e-27 92.9 1.4 1.8e-26 92.0 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 GAK67330.1 - 2.9e-09 36.3 0.2 7.9e-09 35.0 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 GAK67330.1 - 1.1e-07 31.4 1.5 0.0001 21.8 0.0 2.9 2 1 1 3 3 3 2 Zinc-binding dehydrogenase TF_Zn_Ribbon PF08271.7 GAK67330.1 - 0.00012 21.3 1.1 0.0003 20.0 0.8 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding ADH_zinc_N_2 PF13602.1 GAK67330.1 - 0.00049 21.0 0.0 0.0024 18.7 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-ribbon_3 PF13248.1 GAK67330.1 - 0.0029 16.7 0.5 0.0029 16.7 0.4 1.9 2 0 0 2 2 1 1 zinc-ribbon domain 2-Hacid_dh_C PF02826.14 GAK67330.1 - 0.012 14.8 0.0 0.037 13.1 0.0 1.8 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 GAK67330.1 - 0.048 13.5 0.0 0.048 13.5 0.0 2.5 3 1 1 4 4 3 0 short chain dehydrogenase PhnA_Zn_Ribbon PF08274.7 GAK67330.1 - 0.057 13.2 1.3 0.13 12.0 0.9 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DZR PF12773.2 GAK67330.1 - 0.12 12.1 3.3 0.84 9.4 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF1675 PF07897.6 GAK67330.1 - 4.8 6.9 18.7 0.21 11.4 8.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) SurE PF01975.12 GAK67332.1 - 9.9e-43 145.7 0.0 1.4e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Cation_ATPase_C PF00689.16 GAK67333.1 - 0.0035 16.8 3.7 0.0058 16.1 2.6 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus PIG-P PF08510.7 GAK67333.1 - 0.036 13.7 1.8 0.063 12.9 1.3 1.4 1 0 0 1 1 1 0 PIG-P Fijivirus_P9-2 PF06837.6 GAK67333.1 - 0.073 12.1 0.8 0.11 11.6 0.5 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein ALMT PF11744.3 GAK67333.1 - 0.44 9.1 2.3 0.84 8.2 1.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Sugar_tr PF00083.19 GAK67334.1 - 4e-17 61.9 27.1 1.2e-15 57.1 18.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.19 GAK67336.1 - 5e-53 180.2 1.5 5.7e-53 180.0 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAK67336.1 - 1.3e-05 25.5 0.8 0.0062 16.9 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAK67336.1 - 5.2e-05 23.2 4.2 0.0064 16.3 2.9 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAK67336.1 - 0.00026 20.2 1.1 0.00043 19.4 0.8 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK67336.1 - 0.00046 20.1 1.2 0.0012 18.7 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAK67336.1 - 0.0017 17.2 6.3 0.0073 15.1 4.4 1.9 1 1 0 1 1 1 1 FAD binding domain Mqo PF06039.10 GAK67336.1 - 0.0018 16.5 0.0 0.24 9.5 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.9 GAK67336.1 - 0.002 16.8 0.6 0.063 11.9 0.5 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 GAK67336.1 - 0.0032 17.2 0.8 0.76 9.5 0.1 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 GAK67336.1 - 0.0086 15.2 0.5 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.14 GAK67336.1 - 0.017 14.1 0.6 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 GAK67336.1 - 0.023 13.6 0.1 2.3 7.0 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 GAK67336.1 - 0.086 11.6 1.8 6.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 GAK67336.1 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 GAK67336.1 - 0.13 11.3 0.2 1.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 GAK67336.1 - 0.34 10.3 1.8 0.34 10.3 0.4 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Nup35_RRM PF05172.8 GAK67337.1 - 3.3e-08 33.2 0.0 7.2e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 GAK67337.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nucleoporin_FG PF13634.1 GAK67337.1 - 0.0037 17.4 44.5 0.0037 17.4 30.8 8.2 4 3 2 6 6 6 2 Nucleoporin FG repeat region Histone PF00125.19 GAK67338.1 - 1.1e-27 95.9 0.0 2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAK67338.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S CENP-T PF15511.1 GAK67338.1 - 0.26 10.5 1.3 0.63 9.2 0.9 1.7 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T ADIP PF11559.3 GAK67339.1 - 2.1e-25 89.3 7.3 2.1e-25 89.3 5.0 4.7 4 1 1 5 5 5 1 Afadin- and alpha -actinin-Binding Shugoshin_N PF07558.6 GAK67339.1 - 0.014 15.0 2.0 2.4 7.9 0.1 2.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Lipase_GDSL PF00657.17 GAK67339.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase TPR_MLP1_2 PF07926.7 GAK67339.1 - 0.21 11.3 32.5 0.42 10.3 0.0 4.8 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein Dabb PF07876.7 GAK67340.1 - 1.5e-19 70.2 0.2 1.7e-19 70.0 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Pyridox_oxidase PF01243.15 GAK67340.1 - 0.15 12.0 0.1 0.79 9.7 0.0 2.1 2 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase NAD_binding_10 PF13460.1 GAK67341.1 - 2.2e-10 40.8 0.0 4.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding ABC2_membrane PF01061.19 GAK67342.1 - 3.9e-68 228.7 54.5 2.5e-39 134.6 12.6 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAK67342.1 - 5.8e-38 130.2 0.1 8.4e-19 68.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 GAK67342.1 - 4.5e-22 77.6 3.5 3e-20 71.8 0.0 3.2 3 0 0 3 3 3 1 CDR ABC transporter AAA_25 PF13481.1 GAK67342.1 - 5e-07 29.3 0.3 0.00026 20.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain ABC_trans_N PF14510.1 GAK67342.1 - 9.4e-06 25.6 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 GAK67342.1 - 3.4e-05 23.2 2.7 0.013 15.0 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 GAK67342.1 - 4.4e-05 23.5 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAK67342.1 - 0.00048 20.4 0.9 0.13 12.5 0.2 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAK67342.1 - 0.0006 19.0 0.5 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAK67342.1 - 0.00074 19.6 2.3 1 9.5 0.2 3.4 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAK67342.1 - 0.003 18.3 0.1 0.16 12.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 GAK67342.1 - 0.0087 16.0 2.6 1.7 8.6 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase SMC_N PF02463.14 GAK67342.1 - 0.018 14.2 0.1 3.7 6.7 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 GAK67342.1 - 0.026 14.1 1.5 0.27 10.8 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 GAK67342.1 - 0.041 14.1 0.4 0.25 11.6 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 GAK67342.1 - 0.048 13.5 0.2 1.9 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAK67342.1 - 0.063 12.7 2.7 3.1 7.2 0.1 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 GAK67342.1 - 0.088 12.5 2.2 12 5.7 0.2 3.2 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 GAK67342.1 - 0.098 12.6 10.2 3.7 7.4 3.6 3.3 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 GAK67342.1 - 0.1 12.0 3.8 0.39 10.1 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.4 GAK67342.1 - 0.15 10.6 0.3 0.39 9.2 0.2 1.6 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_10 PF12846.2 GAK67342.1 - 0.24 10.7 1.0 15 4.9 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain KaiC PF06745.8 GAK67342.1 - 0.32 10.0 2.3 1.4 7.9 0.3 2.5 3 0 0 3 3 3 0 KaiC PduV-EutP PF10662.4 GAK67342.1 - 0.4 10.1 0.8 0.85 9.1 0.2 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 GAK67342.1 - 0.4 10.3 1.4 4.2 6.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain Pantoate_ligase PF02569.10 GAK67342.1 - 0.55 8.9 0.0 0.96 8.1 0.0 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase AAA_15 PF13175.1 GAK67342.1 - 1.3 8.0 0.0 3.4 6.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 GAK67342.1 - 1.4 8.4 7.1 3.7 7.0 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 GAK67342.1 - 2 8.3 10.3 0.047 13.6 0.9 2.8 3 0 0 3 3 3 0 AAA domain Fungal_trans PF04082.13 GAK67343.1 - 7.7e-18 64.3 0.0 1.6e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAK67344.1 - 1.4e-26 93.4 1.5 1.7e-26 93.1 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK67344.1 - 3.6e-26 92.4 0.4 4.5e-26 92.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK67344.1 - 1e-11 44.8 0.5 1.4e-11 44.4 0.4 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAK67344.1 - 0.0081 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_S31 PF05578.7 GAK67344.1 - 0.037 13.2 0.1 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 Epimerase PF01370.16 GAK67344.1 - 0.05 13.0 1.2 0.1 11.9 0.8 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SBP_bac_11 PF13531.1 GAK67344.1 - 0.058 13.0 1.0 0.1 12.2 0.7 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein S4 PF01479.20 GAK67344.1 - 0.073 12.5 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 S4 domain DUF1670 PF07900.6 GAK67344.1 - 0.08 12.1 0.1 0.94 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1670) ox_reductase_C PF08635.5 GAK67345.1 - 4.4e-49 165.5 0.0 6.2e-49 165.0 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 GAK67345.1 - 1.6e-12 48.0 0.0 3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAK67345.1 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF4535 PF15054.1 GAK67346.1 - 2 7.8 4.4 1.1 8.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) TFIIA PF03153.8 GAK67347.1 - 0.16 11.8 25.6 0.31 10.8 17.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Proteasome PF00227.21 GAK67350.1 - 2.5e-55 186.7 0.4 4.3e-55 185.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAK67350.1 - 5.1e-14 51.2 0.0 1.3e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Abhydrolase_5 PF12695.2 GAK67350.1 - 3.7e-05 23.5 0.1 0.00026 20.7 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAK67350.1 - 0.0045 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAK67350.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 GAK67350.1 - 0.039 13.5 0.1 0.16 11.5 0.0 2.1 3 0 0 3 3 3 0 Lipase (class 3) Chlorophyllase2 PF12740.2 GAK67350.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PAP_central PF04928.12 GAK67351.1 - 3.5e-105 350.3 0.0 5.3e-105 349.8 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 GAK67351.1 - 8.6e-48 161.8 0.0 1.5e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 GAK67351.1 - 3.9e-09 36.7 0.0 1.1e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Ribosomal_L22 PF00237.14 GAK67352.1 - 1.4e-27 95.6 0.1 2.8e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Herpes_gE PF02480.11 GAK67352.1 - 0.0023 16.2 0.0 0.0042 15.4 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF347 PF03988.7 GAK67352.1 - 0.046 13.6 0.4 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Shisa PF13908.1 GAK67352.1 - 0.058 13.5 0.4 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ELFV_dehydrog PF00208.16 GAK67354.1 - 1.3e-50 172.2 0.0 2e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 GAK67354.1 - 4.5e-24 84.0 0.0 1.5e-16 59.1 0.0 2.5 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 GAK67354.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Arrestin_N PF00339.24 GAK67355.1 - 9.2e-06 25.5 0.0 7.7e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Abhydrolase_6 PF12697.2 GAK67356.1 - 4.9e-32 111.6 4.4 8.8e-32 110.8 3.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK67356.1 - 3.4e-14 52.9 0.1 1e-13 51.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK67356.1 - 1.9e-11 43.9 0.4 4.1e-11 42.8 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family CMD PF02627.15 GAK67356.1 - 4.4e-09 36.0 0.3 1.2e-08 34.6 0.2 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Peptidase_S9 PF00326.16 GAK67356.1 - 1.8e-05 24.0 0.0 0.035 13.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.9 GAK67356.1 - 8.6e-05 21.1 0.0 0.00024 19.7 0.0 1.7 1 1 0 1 1 1 1 Ndr family Esterase PF00756.15 GAK67356.1 - 9.4e-05 21.9 0.1 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 GAK67356.1 - 0.013 15.2 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 GAK67356.1 - 0.054 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.13 GAK67356.1 - 0.072 12.3 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 GAK67356.1 - 0.086 12.5 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Dioxygenase_C PF00775.16 GAK67357.1 - 2.7e-09 36.5 2.1 7.7e-07 28.5 0.0 2.6 2 1 0 2 2 2 2 Dioxygenase DNA_methylase PF00145.12 GAK67358.1 - 3.3e-48 164.5 0.0 9.1e-48 163.0 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 GAK67358.1 - 0.071 12.8 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 BAH domain ENTH PF01417.15 GAK67359.1 - 1.8e-44 150.6 0.2 2.6e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 GAK67359.1 - 3.6e-05 22.6 0.0 5.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF3542 PF12061.3 GAK67359.1 - 0.027 13.4 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) GRP PF07172.6 GAK67359.1 - 0.21 12.0 14.1 0.47 10.9 9.8 1.5 1 0 0 1 1 1 0 Glycine rich protein family Peptidase_M16 PF00675.15 GAK67360.1 - 4e-56 188.9 0.2 8.9e-56 187.7 0.2 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAK67360.1 - 1.2e-42 145.6 0.0 1.7e-40 138.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain WD40 PF00400.27 GAK67361.1 - 2.3e-07 30.3 0.0 0.0035 17.1 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat EF-hand_7 PF13499.1 GAK67363.1 - 8.6e-09 35.4 0.1 8.6e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAK67363.1 - 3.8e-08 32.5 0.1 0.0075 16.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 GAK67363.1 - 3.3e-07 29.1 0.1 0.0028 16.8 0.0 2.6 2 0 0 2 2 2 2 EF hand RRM_1 PF00076.17 GAK67363.1 - 6.8e-07 28.8 0.0 1.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_5 PF13202.1 GAK67363.1 - 2e-06 26.8 0.1 0.0016 17.6 0.0 2.6 2 0 0 2 2 2 2 EF hand RRM_6 PF14259.1 GAK67363.1 - 5.3e-06 26.3 0.0 1.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EF-hand_8 PF13833.1 GAK67363.1 - 0.00015 21.3 0.2 0.0034 16.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair RRM_5 PF13893.1 GAK67363.1 - 0.003 17.3 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PepSY_2 PF13670.1 GAK67363.1 - 1.9 8.4 8.8 0.11 12.3 1.5 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Dioxygenase_C PF00775.16 GAK67364.1 - 0.02 14.1 0.3 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 Dioxygenase Aconitase PF00330.15 GAK67366.1 - 1.4e-184 613.9 0.1 1.7e-184 613.6 0.1 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAK67366.1 - 4.5e-44 149.7 0.0 8.5e-44 148.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Chitin_synth_1N PF08407.6 GAK67366.1 - 0.044 13.4 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Chitin synthase N-terminal ABC_membrane PF00664.18 GAK67367.1 - 5e-92 308.2 27.0 6.1e-50 170.1 11.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAK67367.1 - 2.7e-66 222.0 0.0 9.3e-33 113.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAK67367.1 - 1.9e-15 56.7 3.3 5.2e-06 25.8 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAK67367.1 - 1.4e-12 48.2 0.0 0.0018 18.3 0.0 4.2 2 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAK67367.1 - 5.5e-09 35.4 0.4 0.00031 20.2 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 GAK67367.1 - 7.9e-09 34.5 4.2 0.0012 17.5 0.2 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 GAK67367.1 - 4.2e-08 34.0 0.0 0.0044 17.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAK67367.1 - 5.7e-07 29.7 5.4 0.013 15.4 0.3 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAK67367.1 - 1.1e-05 25.5 1.8 0.3 11.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAK67367.1 - 1.9e-05 23.9 0.0 0.19 10.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 GAK67367.1 - 5.4e-05 23.0 2.7 0.18 11.7 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 GAK67367.1 - 6e-05 22.5 0.1 0.042 13.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 GAK67367.1 - 9.2e-05 22.3 0.0 0.58 10.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 GAK67367.1 - 0.00022 21.3 3.9 1.1 9.4 0.2 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAK67367.1 - 0.00094 19.0 0.0 2 8.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAK67367.1 - 0.0012 19.1 0.0 2.8 8.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 GAK67367.1 - 0.0013 19.1 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAK67367.1 - 0.0021 17.8 0.0 2.6 7.7 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 GAK67367.1 - 0.0037 16.3 0.0 1.2 8.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 GAK67367.1 - 0.0075 16.2 0.3 1.9 8.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 GAK67367.1 - 0.011 15.5 0.8 6.7 6.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF815 PF05673.8 GAK67367.1 - 0.012 14.5 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.13 GAK67367.1 - 0.022 14.3 0.0 3.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 GAK67367.1 - 0.024 14.3 0.1 9.2 5.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 GAK67367.1 - 0.031 14.4 0.3 4.7 7.4 0.0 3.4 4 0 0 4 4 3 0 RNA helicase NB-ARC PF00931.17 GAK67367.1 - 0.04 12.7 0.1 3.8 6.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Miro PF08477.8 GAK67367.1 - 0.042 14.3 0.0 8.8 6.8 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_10 PF12846.2 GAK67367.1 - 0.11 11.9 2.6 13 5.0 0.0 3.3 4 0 0 4 4 4 0 AAA-like domain Viral_helicase1 PF01443.13 GAK67367.1 - 0.11 11.9 0.0 2.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.15 GAK67367.1 - 0.12 11.0 8.0 1.1 7.8 0.0 3.0 3 0 0 3 3 2 0 G-protein alpha subunit Dynamin_N PF00350.18 GAK67368.1 - 3.7e-16 59.3 0.3 4.1e-15 56.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAK67368.1 - 4.5e-09 36.2 0.0 2.3e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAK67368.1 - 5.9e-06 25.8 0.0 0.0023 17.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 GAK67368.1 - 0.0027 18.1 0.1 0.2 12.1 0.1 2.8 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 GAK67368.1 - 0.0055 16.2 0.3 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Acylphosphatase PF00708.13 GAK67368.1 - 0.011 15.7 0.2 0.051 13.6 0.0 2.2 2 0 0 2 2 2 0 Acylphosphatase IIGP PF05049.8 GAK67368.1 - 0.027 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 GAK67368.1 - 0.034 13.3 0.1 0.15 11.2 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ABM PF03992.11 GAK67369.1 - 1.1e-06 28.5 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PQ-loop PF04193.9 GAK67370.1 - 1.1e-18 66.4 11.4 1.2e-13 50.3 2.3 2.7 3 0 0 3 3 3 2 PQ loop repeat DUF1301 PF06979.7 GAK67370.1 - 0.0058 16.7 0.0 0.041 14.0 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1301) PepSY_TM_2 PF13703.1 GAK67370.1 - 0.077 13.1 0.2 0.077 13.1 0.1 4.4 4 2 0 4 4 4 0 PepSY-associated TM helix DUF1183 PF06682.7 GAK67371.1 - 1.6e-60 205.3 8.1 4.8e-60 203.8 5.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) CPSase_L_D2 PF02786.12 GAK67372.1 - 7.5e-52 175.6 0.0 1.6e-51 174.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.17 GAK67372.1 - 1.5e-47 162.0 0.1 4.3e-47 160.6 0.1 1.7 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_chain PF00289.17 GAK67372.1 - 1.5e-32 111.9 0.1 1.6e-31 108.6 0.0 2.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAK67372.1 - 1.1e-24 86.4 0.0 3.3e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 GAK67372.1 - 3.3e-11 43.2 0.0 6.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAK67372.1 - 2.6e-10 39.7 3.3 6.1e-10 38.5 2.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 GAK67372.1 - 1.3e-08 33.9 0.0 3.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 GAK67372.1 - 0.00013 21.5 4.4 0.026 14.1 0.5 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 GAK67372.1 - 0.002 18.0 0.0 0.009 15.8 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAK67372.1 - 0.006 16.0 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.1 GAK67372.1 - 0.11 12.7 0.5 1.2 9.5 0.2 2.7 2 0 0 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 GAK67372.1 - 0.29 10.1 0.0 0.56 9.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp FHA PF00498.21 GAK67373.1 - 5.5e-08 32.8 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain HIT PF01230.18 GAK67374.1 - 4.4e-25 88.0 0.2 6.8e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAK67374.1 - 8.3e-14 51.8 0.1 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 GAK67374.1 - 4.3e-05 23.1 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rotamase PF00639.16 GAK67375.1 - 9.7e-24 83.9 0.0 1.8e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 GAK67375.1 - 1.5e-19 70.3 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 GAK67375.1 - 1.1e-06 29.2 0.0 1.8e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 GAK67375.1 - 2.1e-06 27.5 0.3 5.4e-06 26.1 0.2 1.7 1 0 0 1 1 1 1 WW domain Ribosomal_L4 PF00573.17 GAK67376.1 - 0.044 13.1 0.1 0.089 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family SPX PF03105.14 GAK67376.1 - 0.18 11.5 3.0 0.09 12.5 0.1 1.8 2 0 0 2 2 2 0 SPX domain YABBY PF04690.8 GAK67377.1 - 1.8e-08 34.8 0.1 2.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 YABBY protein DUF1014 PF06244.7 GAK67377.1 - 6e-05 23.2 1.1 7.5e-05 22.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box_2 PF09011.5 GAK67377.1 - 0.00059 20.1 1.3 0.00098 19.4 0.7 1.4 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.14 GAK67377.1 - 0.0024 18.1 1.2 0.0024 18.1 0.8 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box Pkinase PF00069.20 GAK67378.1 - 1.5e-25 89.8 0.0 6.1e-19 68.1 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67378.1 - 1.9e-06 27.1 0.0 5.3e-05 22.4 0.0 2.6 3 1 0 3 3 3 1 Protein tyrosine kinase WD40 PF00400.27 GAK67379.1 - 0.017 15.0 4.4 4.5 7.3 0.0 4.3 5 1 0 5 5 5 0 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAK67379.1 - 0.022 13.5 0.0 0.056 12.1 0.0 1.6 2 0 0 2 2 2 0 Nup133 N terminal like Ribosomal_L23eN PF03939.8 GAK67380.1 - 2e-18 66.1 13.7 2e-18 66.1 9.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 GAK67380.1 - 1.4e-15 56.9 0.1 2.5e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 AA_permease PF00324.16 GAK67381.1 - 1e-124 416.5 44.1 1.1e-124 416.3 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAK67381.1 - 1e-37 129.7 47.1 1.3e-37 129.3 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.15 GAK67384.1 - 6.8e-38 130.3 0.1 1.3e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 GAK67384.1 - 5.3e-19 67.3 1.0 3.7e-09 35.8 0.1 2.6 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.2 GAK67384.1 - 2.7e-16 59.2 0.0 8.1e-16 57.6 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.1 GAK67384.1 - 1.1e-15 56.8 1.5 2.4e-08 33.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 GAK67384.1 - 4.5e-11 42.0 0.0 7.2e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 GAK67384.1 - 1.3e-07 30.9 0.7 3.1e-07 29.7 0.2 1.9 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.1 GAK67384.1 - 0.00027 21.0 0.0 0.00068 19.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF1720 PF08226.6 GAK67384.1 - 0.0018 18.3 64.1 0.0018 18.3 44.4 5.8 2 1 1 3 3 3 1 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 GAK67384.1 - 0.017 14.4 0.7 0.78 9.1 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 GAK67384.1 - 0.083 12.8 0.0 18 5.5 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain DUF2665 PF11654.3 GAK67385.1 - 1.7e-19 69.0 0.1 2.5e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF2934 PF11154.3 GAK67385.1 - 0.092 12.1 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) zf-RING_2 PF13639.1 GAK67386.1 - 3.9e-12 45.8 10.5 6.2e-12 45.1 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAK67386.1 - 3.2e-10 39.9 2.8 5.5e-10 39.2 2.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAK67386.1 - 3.2e-06 27.0 8.2 4.9e-06 26.4 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK67386.1 - 5.3e-06 25.9 8.3 8.6e-06 25.3 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK67386.1 - 6.6e-06 25.7 7.3 1e-05 25.1 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAK67386.1 - 1.6e-05 24.6 4.1 3.6e-05 23.5 2.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 GAK67386.1 - 1.7e-05 24.4 7.8 2.8e-05 23.7 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 GAK67386.1 - 0.0029 17.5 8.9 0.0047 16.9 6.2 1.3 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H_2 PF13832.1 GAK67386.1 - 0.038 13.9 2.3 0.083 12.8 1.6 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.1 GAK67386.1 - 0.23 11.0 8.6 0.44 10.1 5.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.1 GAK67386.1 - 0.3 11.2 5.2 0.75 9.9 3.6 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain RINGv PF12906.2 GAK67386.1 - 1 9.4 11.1 1.7 8.7 7.7 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 GAK67386.1 - 7.2 6.5 5.3 25 4.8 3.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PTPlike_phytase PF14566.1 GAK67388.1 - 5.1e-122 403.0 0.0 2.1e-41 141.4 0.0 3.5 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 GAK67388.1 - 4.2e-09 36.0 0.0 0.17 11.4 0.0 4.0 4 0 0 4 4 4 3 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 GAK67388.1 - 1.6e-06 28.5 0.0 0.89 9.7 0.0 3.9 4 0 0 4 4 4 2 Tyrosine phosphatase family TFIIE-A_C-term PF11521.3 GAK67388.1 - 4e-05 23.4 0.0 0.35 10.8 0.0 3.6 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha Y_phosphatase PF00102.22 GAK67388.1 - 0.00045 19.6 0.1 1 8.6 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Creb_binding PF09030.5 GAK67388.1 - 3.4 7.8 7.1 0.3 11.2 0.6 2.3 2 0 0 2 2 2 0 Creb binding HisG PF01634.13 GAK67389.1 - 1.3e-46 158.1 0.1 2.4e-46 157.2 0.1 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 GAK67389.1 - 3.4e-26 91.0 0.1 7.6e-26 89.8 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 GAK67389.1 - 0.0098 15.4 0.0 0.9 9.0 0.0 2.4 2 0 0 2 2 2 2 NMT1/THI5 like Cation_efflux PF01545.16 GAK67390.1 - 3.6e-14 52.5 1.8 3.6e-14 52.5 1.2 1.6 2 0 0 2 2 2 1 Cation efflux family Pkinase PF00069.20 GAK67391.1 - 1.4e-70 237.4 0.0 1.8e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67391.1 - 1.9e-35 122.2 0.0 2.5e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short PF00106.20 GAK67391.1 - 4.7e-14 52.6 1.1 5.2e-13 49.2 0.7 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Kinase-like PF14531.1 GAK67391.1 - 2.5e-08 33.2 0.0 3.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 GAK67391.1 - 4.5e-05 22.8 0.0 8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 GAK67391.1 - 6.8e-05 22.0 0.1 0.00016 20.8 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KR PF08659.5 GAK67391.1 - 0.00012 21.7 1.0 0.00064 19.4 0.7 2.1 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAK67391.1 - 0.00059 19.0 0.0 0.00096 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) APH PF01636.18 GAK67391.1 - 0.00098 18.9 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family NmrA PF05368.8 GAK67391.1 - 0.069 12.3 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 GAK67391.1 - 0.083 12.8 1.6 0.23 11.4 0.2 2.2 2 0 0 2 2 2 0 NADH(P)-binding EcKinase PF02958.15 GAK67391.1 - 0.092 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 GAK67391.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 GAK67391.1 - 0.22 10.3 0.1 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DAGK_cat PF00781.19 GAK67392.1 - 3e-20 71.9 0.0 5.4e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RibD_C PF01872.12 GAK67393.1 - 7.9e-33 113.7 0.1 1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain HMG_box PF00505.14 GAK67394.1 - 6.4e-11 42.3 4.3 7.2e-10 38.9 3.0 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAK67394.1 - 0.0014 18.9 1.5 0.0033 17.7 1.0 1.6 1 0 0 1 1 1 1 HMG-box domain ubiquitin PF00240.18 GAK67395.1 - 8.3e-25 85.9 0.3 9.2e-25 85.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAK67395.1 - 6.2e-17 61.0 0.3 6.8e-17 60.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAK67395.1 - 0.00014 22.0 0.1 0.0004 20.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAK67395.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like tRNA-synt_His PF13393.1 GAK67396.1 - 5.6e-42 143.8 0.1 1e-35 123.3 0.0 3.1 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 GAK67396.1 - 1.5e-17 63.7 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAK67396.1 - 2e-08 34.0 0.2 6.5e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 GAK67396.1 - 0.00021 20.1 0.3 0.083 11.6 0.1 3.0 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 GAK67396.1 - 0.0014 17.8 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Ribosomal_60s PF00428.14 GAK67396.1 - 0.015 15.6 0.4 0.015 15.6 0.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein APG6 PF04111.7 GAK67396.1 - 0.068 12.2 0.5 0.11 11.5 0.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Use1 PF09753.4 GAK67397.1 - 9.8e-11 41.5 0.0 3.3e-10 39.8 0.0 1.8 2 1 1 3 3 3 1 Membrane fusion protein Use1 zf-HC5HC2H_2 PF13832.1 GAK67398.1 - 7.4e-34 116.0 6.4 7.4e-34 116.0 4.4 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAK67398.1 - 4.8e-25 87.5 4.2 4.8e-25 87.5 2.9 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 GAK67398.1 - 1.9e-23 83.4 0.3 1.9e-23 83.4 0.2 3.3 3 0 0 3 3 3 1 Enhancer of polycomb-like Bromodomain PF00439.20 GAK67398.1 - 1.3e-17 63.5 0.2 2.6e-17 62.5 0.2 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 GAK67398.1 - 1e-14 53.5 2.6 1e-14 53.5 1.8 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.12 GAK67398.1 - 7.6e-11 42.0 0.2 2.2e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 GAK67398.1 - 3e-10 39.6 21.1 3.9e-10 39.2 4.0 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 GAK67398.1 - 0.0013 18.7 14.3 0.0065 16.4 3.3 2.6 2 0 0 2 2 2 2 RING-like domain zf-PHD-like PF15446.1 GAK67398.1 - 0.0045 16.3 0.9 0.0045 16.3 0.6 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 GAK67398.1 - 0.013 15.1 0.4 0.013 15.1 0.3 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Coiled-coil_56 PF09813.4 GAK67399.1 - 6.1e-05 22.9 0.0 8.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Scramblase PF03803.10 GAK67400.1 - 6.8e-62 208.4 0.0 8.9e-62 208.0 0.0 1.1 1 0 0 1 1 1 1 Scramblase Romo1 PF10247.4 GAK67401.1 - 8.7e-25 86.7 8.9 1.1e-24 86.3 6.2 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Macro PF01661.16 GAK67402.1 - 3e-42 143.2 0.2 4.7e-42 142.6 0.1 1.3 1 0 0 1 1 1 1 Macro domain DUF1955 PF09205.5 GAK67402.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Peptidase_M24 PF00557.19 GAK67403.1 - 4.4e-42 144.0 0.4 5.7e-42 143.6 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TFIIF_alpha PF05793.7 GAK67403.1 - 0.0037 15.7 10.6 0.0052 15.2 7.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.8 GAK67403.1 - 0.014 15.0 8.3 0.022 14.3 5.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.6 GAK67403.1 - 0.018 14.0 6.3 0.033 13.1 4.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 GAK67403.1 - 0.018 13.0 8.3 0.026 12.4 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 GAK67403.1 - 0.049 12.9 10.3 0.068 12.4 7.1 1.1 1 0 0 1 1 1 0 SDA1 BAF1_ABF1 PF04684.8 GAK67403.1 - 0.14 10.9 16.2 0.021 13.6 7.6 1.9 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Sigma70_ner PF04546.8 GAK67403.1 - 0.36 10.4 7.9 0.93 9.0 5.5 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 GAK67403.1 - 0.38 10.2 7.8 0.78 9.2 5.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 GAK67403.1 - 0.5 8.3 7.2 0.69 7.8 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.9 GAK67403.1 - 1 7.8 12.2 1.5 7.1 8.4 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Tom37_C PF11801.3 GAK67403.1 - 2.6 7.8 5.8 2 8.2 2.1 1.9 2 0 0 2 2 2 0 Tom37 C-terminal domain GATase_2 PF00310.16 GAK67404.1 - 3.5e-25 88.4 0.0 4.5e-20 71.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAK67404.1 - 2.2e-15 56.7 0.0 8.2e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 GAK67404.1 - 1.5e-13 50.5 0.3 8.3e-13 48.1 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 GAK67404.1 - 2.7e-12 46.5 0.0 5.5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 GAK67404.1 - 2.5e-07 29.6 0.0 6.6e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Ribosomal_60s PF00428.14 GAK67404.1 - 0.18 12.2 5.9 0.54 10.6 4.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein cwf18 PF08315.7 GAK67405.1 - 1.5e-26 93.3 7.2 2.3e-26 92.7 5.0 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor YL1 PF05764.8 GAK67406.1 - 4.1e-49 167.3 16.8 4.1e-49 167.3 11.7 2.6 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 GAK67406.1 - 2.7e-14 52.3 0.4 4.5e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.1 GAK67407.1 - 0.0031 17.2 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK67407.1 - 0.059 13.7 0.0 0.2 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 GAK67407.1 - 0.06 13.9 0.0 1.2 9.7 0.0 2.7 1 1 0 1 1 1 0 Methyltransferase domain zf-RING_6 PF14835.1 GAK67408.1 - 0.18 11.5 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein SIMPL PF04402.9 GAK67408.1 - 0.23 11.3 3.3 0.51 10.1 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) zf-C2H2 PF00096.21 GAK67408.1 - 0.23 11.8 2.4 0.59 10.5 1.7 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK67408.1 - 2.6 8.5 5.9 5.3 7.6 4.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3808 PF10300.4 GAK67409.1 - 2.7e-74 250.4 0.6 4.6e-74 249.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.15 GAK67409.1 - 2.8e-34 117.9 0.1 5.1e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 GAK67409.1 - 4e-14 52.7 0.0 1.1e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAK67409.1 - 6.8e-12 45.3 0.5 2.7e-11 43.4 0.4 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPR_12 PF13424.1 GAK67409.1 - 4e-05 23.4 2.2 0.18 11.7 0.8 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAK67409.1 - 4.5e-05 22.9 6.8 0.076 12.6 1.1 5.1 3 2 1 4 4 4 1 TPR repeat DUF4366 PF14283.1 GAK67409.1 - 0.00073 19.0 2.1 0.00073 19.0 1.5 3.2 2 1 2 4 4 3 1 Domain of unknown function (DUF4366) Ribosomal_60s PF00428.14 GAK67409.1 - 0.00075 19.8 12.7 0.00075 19.8 8.8 5.6 4 1 1 5 5 2 1 60s Acidic ribosomal protein TPR_2 PF07719.12 GAK67409.1 - 0.004 16.9 10.5 0.98 9.4 0.7 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAK67409.1 - 0.092 13.2 4.3 1.3 9.6 0.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TctA PF01970.11 GAK67409.1 - 0.35 9.2 0.0 0.73 8.1 0.0 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family TPR_7 PF13176.1 GAK67409.1 - 0.81 9.6 3.3 2.9 7.9 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAK67409.1 - 3.4 7.4 8.4 0.6 9.8 0.2 4.1 7 0 0 7 7 7 0 Tetratricopeptide repeat DIOX_N PF14226.1 GAK67410.1 - 1.3e-10 41.8 0.0 2.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAK67410.1 - 3.3e-09 36.9 0.1 7.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.16 GAK67411.1 - 5.4e-44 150.7 0.9 1.5e-42 145.9 0.3 2.2 2 0 0 2 2 2 2 Amidase Amidohydro_1 PF01979.15 GAK67413.1 - 1.9e-59 201.9 0.8 3e-59 201.3 0.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 GAK67413.1 - 6e-56 187.7 0.3 1.2e-55 186.8 0.2 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 GAK67413.1 - 1.9e-39 133.6 1.1 3.2e-39 132.9 0.2 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.15 GAK67413.1 - 8.3e-34 115.4 0.0 2.7e-33 113.7 0.0 1.9 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.6 GAK67413.1 - 1.8e-06 27.4 0.3 1.6e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAK67413.1 - 1.9e-05 24.3 2.8 6.9e-05 22.5 1.9 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 GAK67413.1 - 0.00019 21.5 7.0 0.052 13.5 0.2 3.5 3 1 1 4 4 4 2 Amidohydrolase Flavin_Reduct PF01613.13 GAK67414.1 - 2.1e-32 112.1 0.4 2.6e-32 111.8 0.3 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_1 PF00561.15 GAK67415.1 - 2.6e-17 63.1 0.0 1e-12 48.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK67415.1 - 1.3e-11 44.8 3.8 1.5e-10 41.3 2.6 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAK67415.1 - 0.0015 18.0 0.1 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 GAK67415.1 - 0.0033 17.1 0.1 0.15 11.8 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Seipin PF06775.9 GAK67417.1 - 1e-63 214.4 0.0 1.6e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Suf PF05843.9 GAK67417.1 - 0.18 11.5 5.8 0.31 10.7 4.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 GAK67417.1 - 1.6 8.7 10.7 0.95 9.5 5.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_92 PF07971.7 GAK67418.1 - 3.4e-130 435.0 0.0 4.3e-130 434.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Aldo_ket_red PF00248.16 GAK67419.1 - 1.4e-39 135.5 0.0 1.8e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3128 PF11326.3 GAK67419.1 - 0.0036 17.3 0.3 0.0088 16.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) YflT PF11181.3 GAK67419.1 - 0.021 14.9 0.0 0.085 13.0 0.0 2.0 1 0 0 1 1 1 0 Heat induced stress protein YflT Cmc1 PF08583.5 GAK67419.1 - 0.037 13.8 0.4 0.071 12.8 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 GAK67419.1 - 0.086 12.8 0.7 0.21 11.5 0.5 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TAP42 PF04177.7 GAK67420.1 - 5.6e-78 262.2 0.0 7.1e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family RRXRR PF14239.1 GAK67420.1 - 0.011 15.2 0.0 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 RRXRR protein TMEM171 PF15471.1 GAK67420.1 - 0.019 13.7 0.7 0.042 12.6 0.5 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 PBP1_TM PF14812.1 GAK67420.1 - 0.42 10.9 4.7 8.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_fiss_reg PF05308.6 GAK67420.1 - 1.5 8.1 13.9 9.5 5.5 6.9 2.5 2 1 0 2 2 2 0 Mitochondrial fission regulator Ribosomal_L10 PF00466.15 GAK67422.1 - 1.8e-26 91.9 0.0 3.6e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 GAK67422.1 - 9e-22 77.2 9.8 8.9e-21 74.0 6.5 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF1021 PF06257.6 GAK67422.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) LIM PF00412.17 GAK67423.1 - 1e-12 47.8 31.9 2.1e-05 24.4 1.3 6.4 6 0 0 6 6 6 4 LIM domain OrfB_Zn_ribbon PF07282.6 GAK67423.1 - 0.16 11.6 0.1 0.16 11.6 0.1 6.4 6 2 1 7 7 7 0 Putative transposase DNA-binding domain Mut7-C PF01927.11 GAK67423.1 - 2.9 7.8 11.3 2.9 7.8 0.3 3.4 3 0 0 3 3 3 0 Mut7-C RNAse domain Epimerase PF01370.16 GAK67424.1 - 2e-41 141.9 0.0 2.6e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 GAK67424.1 - 8.9e-26 89.6 0.0 1.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit RmlD_sub_bind PF04321.12 GAK67424.1 - 2.4e-10 39.8 0.0 5.5e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAK67424.1 - 3.9e-10 38.8 0.0 1.2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAK67424.1 - 1.1e-07 31.0 0.0 1.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAK67424.1 - 1.5e-06 27.3 0.0 6.7e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAK67424.1 - 6.9e-06 26.0 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK67424.1 - 9.7e-05 22.0 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAK67424.1 - 0.0037 17.2 0.0 0.069 13.1 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 GAK67424.1 - 0.038 13.6 0.0 0.2 11.2 0.0 2.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrpF PF04303.8 GAK67425.1 - 8.1e-53 179.4 0.5 4e-38 131.1 0.1 2.4 2 1 0 2 2 2 2 PrpF protein Acyltransferase PF01553.16 GAK67426.1 - 9.9e-22 76.7 0.0 1.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase NatB_MDM20 PF09797.4 GAK67428.1 - 5.8e-74 248.9 0.0 9.7e-74 248.2 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit BTAD PF03704.12 GAK67428.1 - 0.00029 21.1 1.3 0.00029 21.1 0.9 4.3 4 1 0 4 4 4 1 Bacterial transcriptional activator domain TPR_16 PF13432.1 GAK67428.1 - 0.0034 17.9 5.0 0.14 12.8 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat RPOL_N PF14700.1 GAK67428.1 - 0.024 13.9 0.1 0.05 12.8 0.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal TPR_14 PF13428.1 GAK67428.1 - 3.6 8.4 11.2 1.5 9.6 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1708 PF08101.6 GAK67429.1 - 2e-14 53.3 0.0 3.8e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 GAK67429.1 - 5e-07 29.4 0.0 0.00035 20.2 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain Pyridoxal_deC PF00282.14 GAK67430.1 - 5.8e-63 212.5 0.0 8.4e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAK67430.1 - 0.0018 17.1 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF2195 PF09961.4 GAK67431.1 - 0.052 13.3 0.6 0.085 12.6 0.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) MarB PF13999.1 GAK67431.1 - 3.2 7.4 6.2 0.29 10.7 0.5 2.1 2 0 0 2 2 2 0 MarB protein DUF1510 PF07423.6 GAK67432.1 - 0.00066 19.1 3.1 0.00066 19.1 2.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1510) DUF2613 PF11021.3 GAK67432.1 - 0.099 12.3 0.6 0.22 11.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Daxx PF03344.10 GAK67432.1 - 0.94 7.8 40.4 0.16 10.4 15.8 2.1 2 0 0 2 2 2 0 Daxx Family IncA PF04156.9 GAK67432.1 - 2.3 7.7 6.3 5.8 6.4 0.0 2.2 2 0 0 2 2 2 0 IncA protein MTHFR PF02219.12 GAK67433.1 - 1.5e-102 342.5 0.0 4.7e-84 281.8 0.0 2.1 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase PLDc_2 PF13091.1 GAK67434.1 - 6.3e-16 58.2 0.0 5.5e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain Cpn60_TCP1 PF00118.19 GAK67435.1 - 6.1e-157 523.1 1.7 6.9e-157 522.9 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nol1_Nop2_Fmu PF01189.12 GAK67437.1 - 5.6e-16 58.7 0.1 3.1e-14 53.0 0.1 2.8 1 1 0 1 1 1 1 NOL1/NOP2/sun family Pyrophosphatase PF00719.14 GAK67438.1 - 1.4e-52 177.2 0.2 1.9e-52 176.8 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase COesterase PF00135.23 GAK67439.1 - 6.3e-88 295.7 0.0 7.8e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAK67439.1 - 1.4e-10 41.0 2.5 0.00018 21.1 0.3 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK67439.1 - 0.022 14.5 0.6 0.045 13.5 0.4 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family OTU PF02338.14 GAK67440.1 - 1.4e-09 38.6 0.0 2.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Glyco_hydro_3 PF00933.16 GAK67441.1 - 5.8e-78 261.9 0.0 8.9e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAK67441.1 - 1.6e-47 161.9 0.0 2e-46 158.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAK67441.1 - 9.4e-25 86.3 0.4 1.9e-24 85.3 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain zf-XS PF03470.9 GAK67442.1 - 0.61 10.1 2.6 23 5.1 0.0 2.6 2 0 0 2 2 2 0 XS zinc finger domain Sugar_tr PF00083.19 GAK67443.1 - 2.3e-106 356.0 26.8 3.6e-106 355.4 18.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK67443.1 - 8.1e-26 90.5 72.1 7.1e-24 84.1 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_76 PF03663.9 GAK67444.1 - 2.5e-48 165.3 6.3 3.1e-48 165.0 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Sda PF08970.5 GAK67444.1 - 0.037 13.5 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation inhibitor A C5-epim_C PF06662.8 GAK67444.1 - 0.065 12.5 0.0 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_17 PF00332.13 GAK67445.1 - 6.6e-07 28.6 0.9 1.4e-06 27.5 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF3357 PF11837.3 GAK67445.1 - 0.034 13.9 0.1 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Gypsy PF07253.6 GAK67445.1 - 0.1 10.9 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein DUF1043 PF06295.7 GAK67445.1 - 0.14 11.8 1.2 6.8 6.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) stn_TNFRSF12A PF12191.3 GAK67445.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EphA2_TM PF14575.1 GAK67445.1 - 0.29 11.5 0.1 0.29 11.5 0.1 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 GAK67445.1 - 0.46 10.6 0.1 0.46 10.6 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator FAD_binding_7 PF03441.9 GAK67446.1 - 2.6e-90 302.3 0.0 4.3e-90 301.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAK67446.1 - 2e-42 144.7 0.1 4.3e-42 143.6 0.1 1.5 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 GAK67446.1 - 0.12 12.5 1.7 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Universal stress protein family YbjN PF10722.4 GAK67446.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator Pribosyltran_N PF13793.1 GAK67447.1 - 4.6e-46 155.3 0.2 2.2e-45 153.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAK67447.1 - 7.4e-40 136.6 0.7 2.1e-32 112.3 0.2 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAK67447.1 - 3.4e-12 46.1 1.8 1.3e-11 44.2 0.2 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAK67447.1 - 0.025 13.7 0.1 0.053 12.7 0.0 1.6 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Pil1 PF13805.1 GAK67448.1 - 8.1e-17 61.2 0.5 8.1e-17 61.2 0.3 1.9 2 0 0 2 2 2 1 Eisosome component PIL1 Gp-FAR-1 PF05823.7 GAK67448.1 - 0.0044 16.9 3.9 0.0061 16.5 0.6 2.3 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) AAA_13 PF13166.1 GAK67448.1 - 0.016 13.6 2.6 0.024 13.1 1.8 1.1 1 0 0 1 1 1 0 AAA domain Vps51 PF08700.6 GAK67448.1 - 0.054 13.3 0.6 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Vps51/Vps67 FimP PF09766.4 GAK67448.1 - 0.14 11.2 2.5 0.26 10.2 1.7 1.4 1 0 0 1 1 1 0 Fms-interacting protein IncA PF04156.9 GAK67448.1 - 0.25 10.8 2.1 0.66 9.5 1.5 1.7 1 1 0 1 1 1 0 IncA protein DUF4515 PF14988.1 GAK67448.1 - 0.36 10.4 3.4 0.26 10.9 0.3 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4515) Spc7 PF08317.6 GAK67448.1 - 0.59 8.7 7.4 0.66 8.5 1.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein NIPSNAP PF07978.8 GAK67449.1 - 6.6e-37 125.5 2.7 4.1e-27 94.1 0.2 2.3 2 0 0 2 2 2 2 NIPSNAP Pyridoxal_deC PF00282.14 GAK67450.1 - 3.7e-93 311.9 0.0 6.5e-68 228.8 0.0 2.5 1 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Grp1_Fun34_YaaH PF01184.14 GAK67450.1 - 3.5e-13 49.3 16.4 6e-13 48.5 11.3 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Aminotran_1_2 PF00155.16 GAK67450.1 - 0.038 12.9 0.0 0.99 8.2 0.0 2.6 3 0 0 3 3 3 0 Aminotransferase class I and II Grp1_Fun34_YaaH PF01184.14 GAK67451.1 - 7.7e-69 231.1 18.0 9.2e-69 230.9 12.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BCDHK_Adom3 PF10436.4 GAK67452.1 - 3.3e-46 156.7 0.0 4.7e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAK67452.1 - 3.9e-13 49.1 0.0 1.2e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAK67452.1 - 1.5e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.24 GAK67453.1 - 1.4e-13 51.1 0.0 3.6e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK67453.1 - 5.8e-10 39.4 0.0 5.2e-09 36.3 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAK67453.1 - 4.3e-07 30.1 0.0 1.4e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK67453.1 - 2.1e-05 24.1 0.3 0.00021 20.9 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_11 PF13086.1 GAK67453.1 - 0.0072 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 GAK67453.1 - 0.01 14.7 0.0 0.075 11.9 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase NACHT PF05729.7 GAK67453.1 - 0.019 14.6 0.0 0.052 13.1 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Cdc6_C PF09079.6 GAK67453.1 - 0.084 12.6 0.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 CDC6, C terminal DUF2075 PF09848.4 GAK67453.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_transf_22 PF03901.12 GAK67454.1 - 1e-65 222.3 17.5 4.5e-64 216.9 11.5 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family SPC25 PF06703.6 GAK67455.1 - 5.6e-42 143.0 0.0 6.8e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RRM_1 PF00076.17 GAK67456.1 - 4.1e-11 42.3 0.0 7.3e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK67456.1 - 1.5e-10 40.8 0.0 2.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.6 GAK67456.1 - 0.009 14.8 44.1 0.007 15.1 28.7 2.2 1 1 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B SR-25 PF10500.4 GAK67456.1 - 0.24 10.8 18.7 0.44 9.9 13.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Metaviral_G PF09595.5 GAK67456.1 - 0.57 9.8 9.4 1.2 8.7 6.5 1.5 1 0 0 1 1 1 0 Metaviral_G glycoprotein DUF2417 PF10329.4 GAK67457.1 - 5.1e-12 45.6 0.2 1e-11 44.7 0.1 1.5 1 1 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 GAK67457.1 - 7.9e-05 22.6 0.6 0.00017 21.5 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cytochrom_B_N PF00033.14 GAK67457.1 - 0.096 12.0 7.1 0.58 9.4 5.0 2.1 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Nuc_sug_transp PF04142.10 GAK67458.1 - 6.7e-68 228.4 0.1 1.5e-67 227.2 0.1 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 GAK67458.1 - 2.1e-08 33.4 9.2 3.4e-05 22.9 0.5 2.3 2 0 0 2 2 2 2 UAA transporter family EmrE PF13536.1 GAK67458.1 - 1.7e-05 24.9 2.0 1.7e-05 24.9 1.4 3.2 2 1 2 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 GAK67458.1 - 0.00029 20.8 3.0 0.00029 20.8 2.1 2.7 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 GAK67458.1 - 0.0046 16.6 22.9 0.031 13.9 3.2 3.5 2 2 0 2 2 2 2 Triose-phosphate Transporter family KAR9 PF08580.5 GAK67461.1 - 1.8 6.7 13.4 2.7 6.1 9.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_M36 PF02128.10 GAK67462.1 - 1.5e-124 415.6 4.4 1.8e-123 412.1 3.0 2.5 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 GAK67462.1 - 1.3e-09 37.3 0.0 2.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Nup188 PF10487.4 GAK67463.1 - 3.1e-14 51.9 0.0 1.9e-05 22.8 0.0 3.6 4 0 0 4 4 4 3 Nucleoporin subcomplex protein binding to Pom34 ThiF PF00899.16 GAK67464.1 - 7.3e-40 135.9 0.0 1.2e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.5 GAK67464.1 - 4.3e-24 84.0 0.0 6.8e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 GAK67464.1 - 7.7e-24 83.0 0.3 1.4e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 GAK67464.1 - 8.2e-19 66.7 2.3 1.7e-18 65.6 1.6 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 GAK67464.1 - 0.00042 19.8 0.4 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 GAK67464.1 - 0.0038 17.3 0.0 0.0069 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 GAK67464.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Gmx_para_CXXCG PF09535.5 GAK67464.1 - 0.12 11.3 0.2 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Cellulase PF00150.13 GAK67465.1 - 1.3e-16 60.6 4.9 2e-16 60.0 3.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pex14_N PF04695.8 GAK67465.1 - 0.77 9.7 5.7 0.38 10.7 0.3 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PI3_PI4_kinase PF00454.22 GAK67466.1 - 8.9e-34 116.9 0.0 5.4e-33 114.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 GAK67466.1 - 4.5e-24 84.6 0.1 8.2e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ras PF00071.17 GAK67467.1 - 7.5e-60 200.9 1.1 1e-59 200.5 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK67467.1 - 9.2e-21 74.5 0.2 1.9e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAK67467.1 - 9.7e-16 57.4 0.2 1.2e-15 57.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAK67467.1 - 5.3e-08 32.5 0.3 2e-07 30.6 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAK67467.1 - 6.8e-06 25.3 0.3 9.2e-06 24.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAK67467.1 - 9.9e-06 24.8 0.1 1.5e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAK67467.1 - 4.3e-05 23.4 0.1 0.0001 22.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK67467.1 - 0.027 13.7 0.1 1 8.6 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.1 GAK67467.1 - 0.047 13.6 0.0 9.2 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAK67467.1 - 0.047 13.3 0.2 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 GAK67467.1 - 0.047 13.8 0.0 3.3 7.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.18 GAK67467.1 - 0.081 12.7 0.1 4.9 6.9 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Transket_pyr PF02779.19 GAK67469.1 - 2.3e-46 157.5 0.0 3.9e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAK67469.1 - 3.9e-37 126.9 0.3 1.2e-36 125.3 0.4 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Ser_hydrolase PF06821.8 GAK67469.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase CK_II_beta PF01214.13 GAK67470.1 - 1.1e-71 240.1 0.0 1.4e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Sporozoite_P67 PF05642.6 GAK67470.1 - 8.6 4.0 18.0 12 3.5 12.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PNP_UDP_1 PF01048.15 GAK67471.1 - 2.5e-40 137.9 1.3 3.4e-40 137.4 0.9 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily G-gamma PF00631.17 GAK67472.1 - 6.5e-21 73.8 0.5 1.8e-20 72.4 0.0 2.0 2 0 0 2 2 2 1 GGL domain Iso_dh PF00180.15 GAK67473.1 - 1.5e-71 241.1 0.0 1.8e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Condensation PF00668.15 GAK67473.1 - 0.00048 19.0 0.0 0.00068 18.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain DUF3435 PF11917.3 GAK67474.1 - 7.3e-20 71.0 0.0 1.1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF768 PF05589.6 GAK67474.1 - 0.15 12.0 0.1 0.54 10.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Chitin_synth_2 PF03142.10 GAK67475.1 - 1e-17 63.7 0.1 2.1e-15 56.0 0.1 2.4 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 GAK67475.1 - 6e-06 26.1 4.6 1.3e-05 25.0 3.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK67475.1 - 0.00097 18.9 2.5 0.0061 16.3 0.2 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CMV_1a PF12467.3 GAK67475.1 - 3.4 8.0 10.0 7.6 6.8 6.9 1.6 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family UDPG_MGDP_dh_N PF03721.9 GAK67476.1 - 8.2e-22 77.4 0.0 2e-20 72.9 0.0 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 GAK67476.1 - 2.1e-18 66.3 0.0 1.1e-17 64.0 0.0 2.3 3 0 0 3 3 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 GAK67476.1 - 6e-05 23.1 0.1 0.00029 20.9 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_18 PF12847.2 GAK67476.1 - 0.00057 20.4 0.0 0.0024 18.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_2 PF03446.10 GAK67476.1 - 0.00096 19.0 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 GAK67476.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_31 PF13847.1 GAK67476.1 - 0.0054 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK67476.1 - 0.0059 17.0 0.3 0.19 12.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain GFO_IDH_MocA PF01408.17 GAK67476.1 - 0.032 14.7 0.1 0.2 12.1 0.0 2.4 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold HEM4 PF02602.10 GAK67476.1 - 0.045 12.9 0.4 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD 2-Hacid_dh_C PF02826.14 GAK67476.1 - 0.053 12.6 0.0 2.6 7.1 0.0 2.6 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 GAK67476.1 - 0.058 12.8 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_26 PF13659.1 GAK67476.1 - 0.066 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Dynamin_M PF01031.15 GAK67476.1 - 0.087 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region Peptidase_M56 PF05569.6 GAK67477.1 - 0.19 10.6 2.3 4.6 6.1 1.3 2.2 2 0 0 2 2 2 0 BlaR1 peptidase M56 Consortin_C PF15281.1 GAK67477.1 - 1.3 8.5 3.8 0.31 10.5 0.1 1.7 2 0 0 2 2 2 0 Consortin C-terminus SOBP PF15279.1 GAK67477.1 - 2.3 8.5 31.6 3.9 7.7 21.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Cutinase PF01083.17 GAK67478.1 - 1.1e-29 103.4 2.3 1.6e-29 102.8 1.6 1.3 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 GAK67478.1 - 0.048 13.8 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain T_cell_tran_alt PF15128.1 GAK67479.1 - 0.065 12.6 0.5 0.18 11.2 0.0 1.8 1 1 1 2 2 2 0 T-cell leukemia translocation-altered DUF697 PF05128.7 GAK67479.1 - 0.88 9.0 7.9 0.059 12.8 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF697) YchF-GTPase_C PF06071.8 GAK67480.1 - 7.8e-33 112.1 1.9 8.9e-33 111.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 GAK67480.1 - 4.4e-14 52.4 0.0 4.3e-13 49.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAK67480.1 - 2e-05 23.9 0.0 3.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.1 GAK67480.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DNA_pol_A_exo1 PF01612.15 GAK67481.1 - 4.2e-40 137.0 1.8 1.2e-39 135.6 0.1 2.1 2 0 0 2 2 2 1 3'-5' exonuclease HRDC PF00570.18 GAK67481.1 - 2.6e-12 46.2 0.2 5.8e-12 45.1 0.2 1.6 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.7 GAK67481.1 - 8.7e-12 45.1 4.0 4.3e-10 39.7 0.7 2.9 2 1 0 2 2 2 1 PMC2NT (NUC016) domain RNase_HII PF01351.13 GAK67482.1 - 1.6e-43 148.6 0.0 1.3e-39 135.9 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII DUF3449 PF11931.3 GAK67483.1 - 5.7e-65 218.5 0.0 1.1e-64 217.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 GAK67483.1 - 2.4e-08 33.3 0.1 5.5e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 GAK67483.1 - 0.001 19.2 1.7 0.008 16.3 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAK67483.1 - 0.0027 17.7 0.1 2.9 8.0 0.1 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 GAK67483.1 - 0.0032 17.5 7.1 0.061 13.4 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DEAD PF00270.24 GAK67484.1 - 2e-42 144.5 0.3 7.6e-42 142.6 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK67484.1 - 1.4e-28 98.5 0.2 3.3e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 GAK67484.1 - 0.021 13.2 0.0 0.083 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) ResIII PF04851.10 GAK67484.1 - 0.03 14.1 0.1 0.14 11.9 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 GAK67484.1 - 0.17 11.6 0.4 0.53 10.0 0.2 1.8 1 1 0 1 1 1 0 Part of AAA domain TMPIT PF07851.8 GAK67487.1 - 0.42 9.6 1.3 0.87 8.5 0.9 1.5 1 0 0 1 1 1 0 TMPIT-like protein PAE PF03283.8 GAK67489.1 - 5e-16 58.2 0.3 1e-15 57.2 0.2 1.4 1 0 0 1 1 1 1 Pectinacetylesterase DUF4091 PF13320.1 GAK67489.1 - 0.018 14.9 0.9 0.062 13.2 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) DUF566 PF04484.7 GAK67489.1 - 0.4 10.1 23.8 0.7 9.3 16.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pro-kuma_activ PF09286.6 GAK67490.1 - 4.6e-34 117.5 0.1 8.5e-34 116.6 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAK67490.1 - 1.9e-08 33.8 1.3 2.9e-08 33.2 0.9 1.2 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_17 PF00332.13 GAK67491.1 - 3.9e-12 45.8 0.8 3.4e-09 36.1 0.1 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 LRR19-TM PF15176.1 GAK67491.1 - 0.039 13.6 0.1 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Wzz PF02706.10 GAK67491.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Chain length determinant protein Ribosomal_S11 PF00411.14 GAK67492.1 - 1.1e-11 44.8 0.0 3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S11 VirE2 PF07229.7 GAK67492.1 - 0.71 8.1 3.1 0.94 7.7 2.1 1.1 1 0 0 1 1 1 0 VirE2 COG6 PF06419.6 GAK67493.1 - 8e-120 400.8 0.0 5.4e-119 398.0 0.0 1.8 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 BT1 PF03092.11 GAK67493.1 - 0.13 10.8 0.1 0.22 10.1 0.1 1.3 1 0 0 1 1 1 0 BT1 family DUF92 PF01940.11 GAK67494.1 - 3.7e-51 173.4 11.5 6.4e-51 172.6 8.0 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF92 PTR2 PF00854.16 GAK67495.1 - 8.1e-38 130.1 11.4 9.4e-37 126.6 7.9 2.2 1 1 0 1 1 1 1 POT family FG-GAP PF01839.18 GAK67495.1 - 0.0015 18.1 1.1 0.0033 17.0 0.7 1.6 1 0 0 1 1 1 1 FG-GAP repeat DUF1469 PF07332.6 GAK67495.1 - 3.9 7.2 14.9 0.23 11.1 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) Cation_efflux PF01545.16 GAK67496.1 - 1e-58 198.6 6.4 1e-58 198.6 4.4 3.7 4 1 1 5 5 5 2 Cation efflux family EF-hand_1 PF00036.27 GAK67497.1 - 2.5e-22 76.4 0.0 1.5e-05 23.9 0.0 4.7 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 GAK67497.1 - 3.7e-18 63.7 0.0 4.4e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 GAK67497.1 - 8.1e-17 61.1 0.0 8.6e-08 32.2 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAK67497.1 - 1.1e-16 59.3 0.0 0.00071 18.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 GAK67497.1 - 5.5e-15 54.7 0.5 2.3e-08 33.4 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain pair Extensin_2 PF04554.8 GAK67497.1 - 0.25 11.2 32.2 0.074 12.9 14.4 3.0 1 1 2 3 3 3 0 Extensin-like region PEHE PF15275.1 GAK67498.1 - 0.0002 21.8 4.3 0.0002 21.8 3.0 4.7 5 1 1 6 6 6 2 PEHE domain SAS4 PF15460.1 GAK67498.1 - 0.0051 16.6 1.2 0.0051 16.6 0.9 2.0 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 Mad3_BUB1_I PF08311.7 GAK67499.1 - 5.9e-36 123.0 0.1 9.9e-36 122.3 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 GAK67499.1 - 1.3e-12 47.4 0.0 2.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_12 PF13424.1 GAK67499.1 - 0.64 9.9 5.1 0.39 10.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_viral_N PF00242.12 GAK67499.1 - 0.84 8.5 7.4 1.6 7.6 5.2 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PBP1_TM PF14812.1 GAK67499.1 - 6.9 7.0 48.6 0.075 13.3 4.3 6.7 6 0 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exo_endo_phos PF03372.18 GAK67500.1 - 3.1e-17 63.3 0.0 4.2e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAK67500.1 - 9.7e-05 21.9 0.0 0.00025 20.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Glyco_hydro_43 PF04616.9 GAK67502.1 - 2.2e-63 214.0 1.3 3.2e-63 213.4 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PolyA_pol PF01743.15 GAK67503.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Poly A polymerase head domain DHDPS PF00701.17 GAK67504.1 - 1.2e-39 135.6 0.0 1.4e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 GAK67505.1 - 1.6e-29 102.7 22.2 2.5e-29 102.1 15.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1469 PF07332.6 GAK67505.1 - 6.3 6.5 7.4 0.27 10.9 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) ESSS PF10183.4 GAK67505.1 - 8.7 6.7 7.2 72 3.8 0.1 4.1 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fungal_trans PF04082.13 GAK67506.1 - 1.2e-23 83.3 0.0 2.2e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK67506.1 - 1e-06 28.5 12.2 2.4e-06 27.3 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 GAK67507.1 - 1.4e-21 76.8 0.1 3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 adh_short PF00106.20 GAK67507.1 - 1.6e-18 67.1 0.5 1.6e-18 67.1 0.3 2.2 3 0 0 3 3 3 1 short chain dehydrogenase M20_dimer PF07687.9 GAK67507.1 - 2.3e-14 53.0 0.0 5.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain KR PF08659.5 GAK67507.1 - 7e-09 35.5 0.5 2.2e-08 33.9 0.3 1.8 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAK67507.1 - 2.1e-06 27.6 0.1 3.5e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 GAK67507.1 - 4.3e-06 25.8 0.0 6.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAK67507.1 - 0.00013 20.9 0.4 0.00018 20.4 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MHCassoc_trimer PF08831.5 GAK67507.1 - 0.00073 19.3 0.9 0.0016 18.2 0.6 1.5 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain Epimerase PF01370.16 GAK67507.1 - 0.00089 18.7 0.1 0.0029 17.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK67507.1 - 0.0013 17.4 0.3 0.0024 16.6 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAK67507.1 - 0.0083 16.1 1.4 0.024 14.6 1.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding PALP PF00291.20 GAK67508.1 - 8e-47 159.9 0.7 9.9e-47 159.6 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FA_hydroxylase PF04116.8 GAK67509.1 - 3.4e-12 46.7 14.6 3.4e-12 46.7 10.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Erg28 PF03694.8 GAK67509.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Erg28 like protein Tic20 PF09685.5 GAK67509.1 - 5.4 7.0 6.8 1.1 9.2 0.3 2.6 1 1 1 2 2 2 0 Tic20-like protein Rrn6 PF10214.4 GAK67510.1 - 3.6e-12 45.2 18.6 0.0007 17.8 0.0 4.7 4 1 0 4 4 4 3 RNA polymerase I-specific transcription-initiation factor Cation_efflux PF01545.16 GAK67511.1 - 1.6e-42 145.5 9.4 2.2e-42 145.0 6.5 1.2 1 0 0 1 1 1 1 Cation efflux family Myotub-related PF06602.9 GAK67512.1 - 7.2e-118 393.3 0.0 9.5e-117 389.7 0.0 2.0 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 GAK67512.1 - 0.014 14.7 0.1 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAK67512.1 - 0.022 15.0 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 GAK67512.1 - 0.044 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain V-SNARE PF05008.10 GAK67513.1 - 1.4e-21 76.3 10.6 3e-21 75.3 1.5 2.5 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 GAK67513.1 - 4.2e-17 61.9 6.0 4.2e-17 61.9 4.2 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus ApoLp-III PF07464.6 GAK67513.1 - 7.1e-05 22.8 5.7 0.003 17.6 0.4 2.1 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.8 GAK67513.1 - 0.00011 22.5 8.0 0.062 13.7 0.2 3.1 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF883) Sec20 PF03908.8 GAK67513.1 - 0.00023 20.8 0.4 0.00023 20.8 0.3 1.9 2 0 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 GAK67513.1 - 0.0072 14.4 0.6 0.0072 14.4 0.4 1.6 2 0 0 2 2 2 1 Fusion glycoprotein F0 DUF3391 PF11871.3 GAK67513.1 - 0.01 16.0 8.8 0.33 11.1 1.4 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3391) Prominin PF05478.6 GAK67513.1 - 0.01 13.4 2.6 0.016 12.7 1.8 1.4 1 1 0 1 1 1 0 Prominin YukC PF10140.4 GAK67513.1 - 0.019 13.5 0.7 0.023 13.3 0.0 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC PTS_IIA PF02255.11 GAK67513.1 - 0.031 14.1 1.7 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit HHV6-IE PF03753.8 GAK67513.1 - 0.043 11.3 0.0 0.063 10.7 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein YqjK PF13997.1 GAK67513.1 - 0.052 13.7 0.7 0.052 13.7 0.5 1.8 2 0 0 2 2 1 0 YqjK-like protein T2SF PF00482.18 GAK67513.1 - 0.059 13.2 1.6 0.46 10.3 0.9 2.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF607 PF04678.8 GAK67513.1 - 0.091 12.6 1.4 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF912 PF06024.7 GAK67513.1 - 0.092 12.7 0.2 0.092 12.7 0.2 2.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2130 PF09903.4 GAK67513.1 - 0.11 11.1 4.3 0.75 8.4 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) BLOC1_2 PF10046.4 GAK67513.1 - 0.13 12.4 5.5 0.79 9.9 0.3 2.4 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT57 PF10498.4 GAK67513.1 - 0.22 10.2 3.4 3.8 6.1 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Sec8_exocyst PF04048.9 GAK67513.1 - 0.22 11.1 5.6 0.43 10.2 1.2 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Trichoplein PF13868.1 GAK67513.1 - 0.28 9.5 13.5 0.058 11.7 2.8 2.0 2 0 0 2 2 2 0 Tumour suppressor, Mitostatin DUF4600 PF15372.1 GAK67513.1 - 0.38 10.9 7.2 0.74 10.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Fib_alpha PF08702.5 GAK67513.1 - 0.51 10.4 3.6 7.7 6.6 0.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CASP_C PF08172.7 GAK67513.1 - 0.72 8.8 7.8 2 7.3 0.4 2.3 1 1 1 2 2 2 0 CASP C terminal Apolipoprotein PF01442.13 GAK67513.1 - 0.76 9.2 10.6 3.2 7.2 0.5 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Sigma_reg_N PF13800.1 GAK67513.1 - 1.1 9.3 5.7 0.65 10.0 2.3 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal OmpH PF03938.9 GAK67513.1 - 1.2 9.0 13.6 1.1 9.1 1.8 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Flagellin_N PF00669.15 GAK67513.1 - 6.6 6.5 13.8 2.8 7.7 6.2 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Abhydrolase_6 PF12697.2 GAK67514.1 - 2.5e-30 106.0 2.0 5.9e-30 104.8 0.2 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK67514.1 - 5.7e-18 65.3 0.0 5.1e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK67514.1 - 1.1e-13 51.1 0.0 4.5e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 GAK67514.1 - 3.4e-06 26.6 0.0 7.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 GAK67514.1 - 1.6e-05 24.5 0.0 0.01 15.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 GAK67514.1 - 0.00012 21.8 0.0 0.051 13.2 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 GAK67514.1 - 0.0013 18.0 0.0 0.29 10.3 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 GAK67514.1 - 0.0015 18.1 2.0 0.0032 17.0 0.0 2.4 3 0 0 3 3 3 1 Serine hydrolase Ndr PF03096.9 GAK67514.1 - 0.0051 15.3 0.0 0.0094 14.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF2305 PF10230.4 GAK67514.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 GAK67514.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 GAK67514.1 - 0.081 12.3 0.0 2.7 7.3 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAK67514.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 GAK67514.1 - 0.14 11.2 0.0 0.51 9.3 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.7 GAK67514.1 - 0.15 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Fumble PF03630.9 GAK67515.1 - 9.5e-114 379.7 0.0 3.4e-86 289.2 0.0 3.1 3 0 0 3 3 3 3 Fumble MFS_1 PF07690.11 GAK67516.1 - 2.1e-34 118.7 19.2 3e-34 118.2 13.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_38 PF01074.17 GAK67517.1 - 2.4e-74 250.0 0.0 3.6e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAK67517.1 - 9.2e-46 156.5 0.0 1.4e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAK67517.1 - 5.6e-24 84.1 0.0 1.2e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 GAK67517.1 - 0.0022 16.9 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Methyltransf_23 PF13489.1 GAK67518.1 - 2.5e-09 37.0 0.0 4.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK67518.1 - 2.1e-07 31.5 0.0 6.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK67518.1 - 0.00058 20.3 0.0 0.012 16.0 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK67518.1 - 0.0017 18.6 0.0 0.0045 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK67518.1 - 0.0019 18.6 0.0 0.0047 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK67518.1 - 0.002 17.7 0.0 0.0049 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK67518.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1317 PF07026.6 GAK67518.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) ACOX PF01756.14 GAK67519.1 - 4.7e-19 68.4 0.1 1.6e-17 63.5 0.0 2.7 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 GAK67519.1 - 3.8e-14 53.0 0.2 1e-13 51.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 GAK67519.1 - 3.1e-10 39.4 0.3 6.4e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Eaf7 PF07904.8 GAK67520.1 - 9.8e-10 38.2 0.4 0.00096 19.0 0.0 3.2 2 1 0 2 2 2 2 Chromatin modification-related protein EAF7 SCO1-SenC PF02630.9 GAK67521.1 - 1.3e-56 190.9 0.0 1.9e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 GAK67521.1 - 0.062 12.9 0.0 0.24 11.1 0.0 2.0 1 1 0 1 1 1 0 AhpC/TSA family DUF4366 PF14283.1 GAK67521.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PIRT PF15099.1 GAK67521.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Tcf25 PF04910.9 GAK67522.1 - 8.1e-97 324.3 0.0 1.2e-96 323.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 NST1 PF13945.1 GAK67522.1 - 1.3 9.0 10.1 2.7 8.0 7.0 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Pro_isomerase PF00160.16 GAK67523.1 - 9.5e-44 149.3 0.1 1.5e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 GAK67523.1 - 2.4e-05 23.9 1.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAK67523.1 - 0.00036 20.2 3.3 0.015 15.1 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAK67523.1 - 0.013 15.1 0.2 0.013 15.1 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAK67523.1 - 0.058 13.3 0.6 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RdRP PF05183.7 GAK67524.1 - 1.1e-134 450.3 0.0 1.5e-134 449.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 GAK67524.1 - 0.0017 18.3 0.0 0.0058 16.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EutB PF06751.6 GAK67524.1 - 0.18 10.1 0.0 1.2 7.3 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine ammonia lyase large subunit (EutB) DUF544 PF04424.8 GAK67525.1 - 7.8e-17 61.2 0.0 2e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Aminotran_4 PF01063.14 GAK67525.1 - 2.4e-12 46.8 0.0 1.3e-11 44.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class IV Fungal_trans PF04082.13 GAK67526.1 - 1.2e-19 70.2 0.2 2.1e-19 69.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK67526.1 - 1.4e-08 34.4 10.0 2.4e-08 33.7 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK67527.1 - 5.8e-26 90.9 0.0 1.1e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK67527.1 - 6.4e-08 32.3 11.1 1.1e-07 31.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSF PF00474.12 GAK67529.1 - 5.2e-17 61.5 32.0 9.8e-17 60.6 22.2 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Kinesin PF00225.18 GAK67530.1 - 4.6e-106 354.2 0.0 6.9e-106 353.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 GAK67530.1 - 3.1e-39 133.8 0.0 1e-38 132.1 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 GAK67530.1 - 2.2e-11 43.8 0.0 7.9e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 GAK67530.1 - 1.3e-09 37.9 0.2 3e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 GAK67530.1 - 6.8e-07 29.3 0.0 1.5e-05 25.0 0.0 2.9 3 0 0 3 3 3 1 FHA domain PH_11 PF15413.1 GAK67530.1 - 5.2e-05 23.4 0.9 0.0001 22.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 GAK67530.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain AmoA PF05145.7 GAK67531.1 - 0.074 12.0 1.7 0.12 11.4 1.2 1.2 1 0 0 1 1 1 0 Putative ammonia monooxygenase PPR_2 PF13041.1 GAK67532.1 - 1.1e-48 162.9 0.2 1.5e-08 34.4 0.0 12.1 9 2 4 13 13 13 10 PPR repeat family PPR_3 PF13812.1 GAK67532.1 - 8.2e-35 116.1 20.8 0.0017 18.5 0.0 15.0 16 0 0 16 16 15 8 Pentatricopeptide repeat domain PPR PF01535.15 GAK67532.1 - 3.2e-32 108.2 14.7 0.00015 21.5 0.0 14.3 18 0 0 18 18 16 6 PPR repeat PPR_1 PF12854.2 GAK67532.1 - 6.3e-20 70.3 6.7 6e-05 22.4 0.0 8.8 8 0 0 8 8 8 4 PPR repeat Methyltransf_11 PF08241.7 GAK67532.1 - 6.5e-13 48.9 0.0 2.8e-12 46.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK67532.1 - 2e-10 40.6 0.0 5.7e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK67532.1 - 6.6e-10 39.3 0.0 2.4e-09 37.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK67532.1 - 5e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAK67532.1 - 4.5e-07 29.2 0.0 9.3e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAK67532.1 - 6.3e-05 23.2 0.1 0.0014 18.9 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK67532.1 - 0.0028 18.2 0.0 0.012 16.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain TPR_7 PF13176.1 GAK67532.1 - 0.0043 16.7 0.0 1.8 8.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Med13_C PF06333.7 GAK67533.1 - 0.00018 20.1 0.0 0.00018 20.1 0.0 3.8 4 1 0 4 4 4 1 Mediator complex subunit 13 C-terminal POP1 PF06978.6 GAK67534.1 - 0.084 12.5 0.6 0.088 12.4 0.4 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Glyco_hydro_cc PF11790.3 GAK67535.1 - 1.3e-62 211.3 8.4 1.7e-62 210.9 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 GAK67535.1 - 0.00077 18.3 0.2 0.00077 18.3 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 Glyco_hydro_2_C PF02836.12 GAK67535.1 - 0.002 17.0 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Mur_ligase_M PF08245.7 GAK67536.1 - 0.00052 20.1 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain DUF3347 PF11827.3 GAK67536.1 - 0.052 13.5 2.5 0.13 12.2 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Asp PF00026.18 GAK67537.1 - 1.5e-07 30.9 0.5 0.028 13.6 0.0 3.4 4 0 0 4 4 4 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAK67537.1 - 0.0018 18.2 0.6 0.0042 17.0 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAK67537.1 - 0.025 15.0 2.6 2.1 8.8 0.4 3.3 2 1 0 2 2 2 0 Aspartyl protease ADH_N PF08240.7 GAK67538.1 - 7.7e-27 93.2 2.4 7.7e-27 93.2 1.7 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAK67538.1 - 3.8e-22 78.2 0.9 7.2e-22 77.3 0.6 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAK67538.1 - 0.018 14.1 0.1 0.034 13.2 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 GAK67538.1 - 1.1 9.0 5.3 2.9 7.7 2.3 2.2 1 1 1 2 2 2 0 ThiF family SNF2_N PF00176.18 GAK67539.1 - 1.7e-66 224.0 0.0 4.4e-66 222.6 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK67539.1 - 5.9e-14 51.6 0.0 1.6e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNF-1A_C PF04813.7 GAK67540.1 - 0.11 12.8 3.2 0.26 11.5 2.3 1.6 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus PIG-X PF08320.7 GAK67541.1 - 9.6e-21 74.0 0.0 5.2e-11 42.2 0.0 2.0 2 0 0 2 2 2 2 PIG-X / PBN1 Ric8 PF10165.4 GAK67542.1 - 3.4e-101 339.2 0.0 1e-100 337.7 0.0 1.7 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn PIP5K PF01504.13 GAK67543.1 - 5.2e-43 146.9 0.0 2.1e-24 86.0 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase XPG_N PF00752.12 GAK67543.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain Glypican PF01153.14 GAK67543.1 - 0.44 9.0 1.1 0.89 8.0 0.8 1.4 1 0 0 1 1 1 0 Glypican CBFD_NFYB_HMF PF00808.18 GAK67544.1 - 1.6e-25 88.9 0.4 2.1e-25 88.5 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAK67544.1 - 8.8e-06 25.7 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 GAK67544.1 - 0.054 13.2 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF4611 PF15387.1 GAK67544.1 - 0.41 10.8 4.6 3.6 7.7 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SNO PF01174.14 GAK67545.1 - 1.6e-52 177.8 0.0 1.8e-42 145.1 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 GAK67545.1 - 2.3e-10 40.3 0.2 3.8e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 GAK67545.1 - 0.00018 21.0 0.1 0.0032 16.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 GAK67545.1 - 0.00021 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 GAK67545.1 - 0.0023 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family BPL_N PF09825.4 GAK67545.1 - 0.0048 15.7 0.0 0.12 11.1 0.0 2.0 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal DUF4066 PF13278.1 GAK67545.1 - 0.064 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative amidotransferase TPR_2 PF07719.12 GAK67546.1 - 5.6e-08 32.1 32.5 0.24 11.4 0.0 9.9 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAK67546.1 - 6.5e-06 26.6 0.8 6.5e-06 26.6 0.6 12.4 11 3 0 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAK67546.1 - 5.1e-05 22.8 44.6 0.00026 20.5 0.2 9.9 8 2 2 10 10 10 3 TPR repeat TPR_1 PF00515.23 GAK67546.1 - 0.00038 19.9 18.5 0.045 13.3 0.6 6.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAK67546.1 - 0.00065 19.3 12.8 18 5.3 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAK67546.1 - 0.14 12.5 57.8 0.12 12.7 0.4 12.1 12 1 0 12 12 12 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAK67546.1 - 0.23 12.2 0.1 0.1 13.2 0.5 13.0 13 3 2 15 15 15 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAK67546.1 - 0.67 10.5 26.6 0.62 10.6 0.1 10.3 10 0 0 10 10 10 0 Tetratricopeptide repeat DHBP_synthase PF00926.14 GAK67547.1 - 6.1e-77 257.2 0.0 7.1e-77 257.0 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Cpn60_TCP1 PF00118.19 GAK67548.1 - 2e-137 458.7 10.7 2.3e-137 458.5 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Proteasome PF00227.21 GAK67549.1 - 2.4e-47 160.6 1.6 4.7e-45 153.2 0.2 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 GAK67549.1 - 2.8e-15 55.2 0.4 5.3e-15 54.4 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nop PF01798.13 GAK67550.1 - 1e-58 196.8 0.1 2.2e-58 195.8 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAK67550.1 - 1.3e-25 88.9 0.0 4.1e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAK67550.1 - 2.6e-18 65.9 0.1 2.6e-18 65.9 0.1 2.6 2 1 0 2 2 2 1 NOP5NT (NUC127) domain SH3_1 PF00018.23 GAK67551.1 - 1.6e-10 40.2 0.4 2.5e-10 39.5 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAK67551.1 - 0.00013 21.3 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAK67551.1 - 0.00096 18.6 0.1 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Fork_head PF00250.13 GAK67552.1 - 4.4e-22 77.9 0.1 1.6e-21 76.1 0.1 1.9 1 1 0 1 1 1 1 Fork head domain VTC PF09359.5 GAK67554.1 - 8.1e-103 343.3 0.9 1.9e-102 342.0 0.0 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 GAK67554.1 - 2.9e-33 115.8 7.6 2.9e-33 115.8 5.3 3.5 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 GAK67554.1 - 6.3e-10 39.1 0.4 6.3e-10 39.1 0.3 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF202) DUF1154 PF06631.6 GAK67554.1 - 0.45 10.2 6.0 14 5.4 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1154) SDA1 PF05285.7 GAK67555.1 - 5.4e-89 298.6 39.5 5.4e-89 298.6 27.4 2.2 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 GAK67555.1 - 1.5e-19 70.0 0.1 3.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 NUC130/3NT domain DEAD PF00270.24 GAK67556.1 - 4e-38 130.5 0.0 4.3e-37 127.2 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK67556.1 - 2.9e-18 65.5 0.0 5.8e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAK67556.1 - 7e-16 57.5 0.1 1.5e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 GAK67556.1 - 3.9e-05 23.5 0.0 8.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DNA_pol_phi PF04931.8 GAK67556.1 - 2.1 6.0 3.3 3.2 5.3 2.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.26 GAK67557.1 - 0.029 14.4 0.2 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF346 PF03984.8 GAK67557.1 - 0.4 10.1 0.2 0.4 10.1 0.1 2.0 3 0 0 3 3 3 0 Repeat of unknown function (DUF346) CPSase_L_D2 PF02786.12 GAK67558.1 - 9.7e-106 351.7 0.0 4.5e-82 274.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 GAK67558.1 - 1.1e-40 138.1 0.9 2.1e-40 137.3 0.3 1.8 2 0 0 2 2 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 GAK67558.1 - 1.2e-36 126.1 0.1 1.2e-17 64.2 0.1 3.0 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 GAK67558.1 - 4e-35 120.2 0.0 4.4e-17 62.1 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 GAK67558.1 - 2.3e-26 92.3 0.0 4.1e-10 38.9 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAK67558.1 - 6.3e-18 64.7 0.0 1e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAK67558.1 - 2.1e-12 46.9 0.1 5.8e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 GAK67558.1 - 4.6e-11 42.5 0.0 5.1e-06 26.0 0.0 3.0 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAK67558.1 - 2.4e-07 30.7 0.0 8.6e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 GAK67558.1 - 1.6e-05 24.2 0.3 0.024 13.8 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 GAK67558.1 - 0.0046 16.8 0.0 0.019 14.8 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain Epimerase PF01370.16 GAK67558.1 - 0.0077 15.6 0.0 0.22 10.9 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ATP-grasp_2 PF08442.5 GAK67558.1 - 0.066 12.5 0.0 4.5 6.6 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain Sigma70_r4_2 PF08281.7 GAK67558.1 - 0.25 10.8 1.5 0.32 10.4 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Peptidase_M17_N PF02789.12 GAK67558.1 - 0.3 10.8 0.0 0.3 10.8 0.0 2.6 3 0 0 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain HLH PF00010.21 GAK67559.1 - 5.9e-15 54.7 0.1 1.1e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyoxalase PF00903.20 GAK67559.1 - 0.027 14.4 0.7 0.11 12.4 0.0 2.2 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2433 PF10360.4 GAK67561.1 - 7.5e-43 146.0 0.2 2.2e-42 144.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 GAK67561.1 - 2.6e-05 23.7 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 GAK67561.1 - 2.9e-05 23.5 0.0 0.012 15.2 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK67561.1 - 0.002 18.0 0.0 0.0057 16.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 GAK67561.1 - 0.073 12.9 0.2 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Cgr1 PF03879.9 GAK67562.1 - 1.1e-28 99.5 24.0 1.2e-28 99.3 16.6 1.0 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 GAK67562.1 - 0.14 11.5 22.7 0.16 11.3 15.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dynamin_N PF00350.18 GAK67562.1 - 0.55 10.0 3.4 0.62 9.8 2.3 1.1 1 0 0 1 1 1 0 Dynamin family Atg14 PF10186.4 GAK67562.1 - 0.77 8.6 13.2 0.93 8.3 9.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PEARLI-4 PF05278.7 GAK67562.1 - 0.79 9.0 11.2 0.89 8.8 7.8 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) APG6 PF04111.7 GAK67562.1 - 1.4 7.9 9.0 1.4 7.8 6.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 G-alpha PF00503.15 GAK67562.1 - 5.2 5.6 9.1 5.7 5.5 6.3 1.0 1 0 0 1 1 1 0 G-protein alpha subunit Borrelia_P83 PF05262.6 GAK67562.1 - 6 5.0 14.0 6.1 4.9 9.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hom_end_hint PF05203.11 GAK67562.1 - 7 6.3 7.7 7.8 6.1 5.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint RR_TM4-6 PF06459.7 GAK67562.1 - 7.8 6.3 13.9 9 6.0 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP_sp32 PF07222.7 GAK67562.1 - 8.1 5.5 9.7 8.9 5.4 6.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GTP_EFTU PF00009.22 GAK67563.1 - 4e-33 114.4 0.5 2.4e-32 111.9 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAK67563.1 - 1e-16 60.7 0.3 7.2e-16 58.0 0.0 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAK67563.1 - 1.1e-14 54.2 4.1 3.3e-10 39.9 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAK67563.1 - 8.5e-07 28.9 0.3 3.8e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAK67563.1 - 0.033 14.3 0.3 0.14 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain CENP-F_C_Rb_bdg PF10490.4 GAK67564.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Cation_ATPase_N PF00690.21 GAK67565.1 - 0.1 12.0 0.5 0.57 9.6 0.0 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Ribosomal_L2_C PF03947.13 GAK67567.1 - 4.1e-42 143.0 1.5 6.8e-42 142.3 1.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAK67567.1 - 5.1e-14 51.9 0.1 1.2e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Rad10 PF03834.9 GAK67568.1 - 1.5e-31 107.9 0.2 2.4e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 GAK67568.1 - 3.1e-09 36.8 0.2 4.8e-08 33.0 0.0 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain UIM PF02809.15 GAK67568.1 - 0.031 13.8 0.4 0.09 12.3 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif HHH_2 PF12826.2 GAK67568.1 - 0.089 12.6 0.0 0.82 9.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif SLT PF01464.15 GAK67569.1 - 4.9e-16 58.3 0.0 4.9e-16 58.3 0.0 2.7 2 2 1 3 3 3 1 Transglycosylase SLT domain Mem_trans PF03547.13 GAK67569.1 - 0.02 13.2 4.3 0.027 12.7 3.0 1.1 1 0 0 1 1 1 0 Membrane transport protein MIP-T3 PF10243.4 GAK67569.1 - 0.022 13.2 18.0 0.027 12.9 12.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 GAK67569.1 - 0.17 11.2 22.6 0.21 10.9 15.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF1675 PF07897.6 GAK67569.1 - 2.1 8.1 28.1 3.3 7.5 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Plasmodium_Vir PF05795.6 GAK67569.1 - 2.7 7.0 14.8 4.4 6.4 10.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Utp14 PF04615.8 GAK67569.1 - 2.9 5.9 21.5 3.8 5.5 14.9 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 GAK67569.1 - 6.9 4.8 40.2 9.1 4.4 27.9 1.1 1 0 0 1 1 1 0 Transmembrane protein BUD22 PF09073.5 GAK67569.1 - 7.8 5.4 32.6 11 4.9 22.6 1.1 1 0 0 1 1 1 0 BUD22 Actin PF00022.14 GAK67570.1 - 1.6e-157 523.9 0.0 2e-157 523.6 0.0 1.1 1 0 0 1 1 1 1 Actin His_biosynth PF00977.16 GAK67570.1 - 6.2e-34 117.2 0.0 1.7e-33 115.8 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein GST_N PF02798.15 GAK67570.1 - 1.5e-09 37.9 0.0 4.6e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAK67570.1 - 2.7e-06 27.4 0.1 7.6e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK67570.1 - 4.4e-06 26.5 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAK67570.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thioredoxin PF00085.15 GAK67571.1 - 1.2e-40 137.3 0.2 1.1e-21 76.4 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 GAK67571.1 - 1.7e-14 54.0 0.0 2e-07 30.9 0.0 3.7 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAK67571.1 - 4.1e-10 39.8 0.2 2.4e-05 24.4 0.0 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 GAK67571.1 - 2.9e-06 27.3 2.1 0.082 12.9 0.1 3.6 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_8 PF13905.1 GAK67571.1 - 3.1e-06 27.1 0.1 0.0034 17.4 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 GAK67571.1 - 6.3e-06 26.1 0.1 0.0002 21.3 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 GAK67571.1 - 9.8e-05 22.0 0.0 0.09 12.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.5 GAK67571.1 - 0.00029 20.4 0.4 0.74 9.3 0.0 2.7 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.16 GAK67571.1 - 0.0095 15.6 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Glutaredoxin PF00462.19 GAK67571.1 - 0.57 10.2 1.8 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Glutaredoxin RICTOR_N PF14664.1 GAK67572.1 - 7e-83 278.2 1.2 1.9e-82 276.7 0.8 1.8 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 GAK67572.1 - 8.8e-81 270.2 0.5 1.2e-78 263.2 0.1 2.9 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 GAK67572.1 - 4.1e-34 116.9 0.1 2.7e-33 114.3 0.0 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 GAK67572.1 - 1.1e-29 102.1 5.6 3e-29 100.7 0.2 3.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 GAK67572.1 - 1.1e-13 50.6 0.5 3.1e-13 49.2 0.3 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.17 GAK67572.1 - 0.013 15.5 4.4 13 6.2 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat AAA PF00004.24 GAK67574.1 - 0.00039 20.6 0.0 0.0011 19.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAK67574.1 - 0.031 14.0 0.6 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 GAK67574.1 - 0.13 12.4 0.8 1 9.4 0.1 2.8 3 1 0 3 3 3 0 AAA domain Rad17 PF03215.10 GAK67574.1 - 0.25 10.0 0.0 0.45 9.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 GAK67574.1 - 0.27 9.8 0.0 0.44 9.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 GAK67574.1 - 0.27 11.1 0.0 0.27 11.1 0.0 4.0 5 1 0 5 5 5 0 AAA ATPase domain Abi PF02517.11 GAK67575.1 - 2.9e-07 30.5 1.3 2.9e-07 30.5 0.9 2.1 3 0 0 3 3 3 1 CAAX protease self-immunity Cyclin_N PF00134.18 GAK67576.1 - 2.3e-14 53.0 2.9 8.6e-14 51.1 0.5 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAK67576.1 - 0.011 15.6 6.1 1.7 8.6 0.2 2.9 2 1 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.14 GAK67576.1 - 0.019 14.7 0.6 0.019 14.7 0.4 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Spt4 PF06093.8 GAK67577.1 - 1.2e-32 111.6 0.0 1.4e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-DHHC PF01529.15 GAK67577.1 - 0.072 12.4 0.7 0.088 12.1 0.5 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase MIF4G_like PF09088.6 GAK67578.1 - 1.4e-67 226.8 0.0 2.5e-67 226.0 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 GAK67578.1 - 3.5e-38 131.2 0.0 8e-38 130.1 0.0 1.6 1 1 0 1 1 1 1 MIF4G like Erythrovirus_X PF06795.6 GAK67578.1 - 0.054 13.5 0.2 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Erythrovirus X protein MIF4G PF02854.14 GAK67578.1 - 0.14 11.5 0.0 0.62 9.4 0.0 1.9 1 1 1 2 2 2 0 MIF4G domain DUF3546 PF12066.3 GAK67579.1 - 2.7e-16 59.5 3.2 6.5e-16 58.3 1.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 GAK67579.1 - 1.4e-11 45.0 0.0 3.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 LIM_bind PF01803.11 GAK67580.1 - 2.5e-37 128.2 0.0 1.4e-19 70.1 0.0 7.8 4 3 1 5 5 5 2 LIM-domain binding protein TAF4 PF05236.9 GAK67581.1 - 7.6e-30 104.0 0.5 2.9e-29 102.1 0.3 1.8 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Got1 PF04178.7 GAK67581.1 - 3.7e-19 68.9 14.5 5.9e-19 68.3 10.0 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family SAGA-Tad1 PF12767.2 GAK67581.1 - 0.022 14.4 4.7 0.023 14.3 1.7 2.1 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit ALG3 PF05208.8 GAK67582.1 - 2e-110 369.4 18.6 3e-110 368.9 12.2 1.8 2 0 0 2 2 2 1 ALG3 protein Gaa1 PF04114.9 GAK67582.1 - 1.4e-42 146.0 24.7 3.9e-42 144.6 2.9 4.3 3 1 0 3 3 3 2 Gaa1-like, GPI transamidase component TIP49 PF06068.8 GAK67583.1 - 4.2e-180 598.7 0.2 7.7e-180 597.8 0.1 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 GAK67583.1 - 1.3e-10 41.6 0.8 2.2e-06 27.9 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAK67583.1 - 9.4e-09 34.6 1.1 2.2e-05 23.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAK67583.1 - 8e-06 26.0 0.5 0.064 13.3 0.1 2.7 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 GAK67583.1 - 5.3e-05 22.9 0.1 0.00043 19.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 GAK67583.1 - 0.0001 22.3 0.0 0.0051 16.8 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 GAK67583.1 - 0.00028 20.6 0.1 0.089 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 GAK67583.1 - 0.00084 19.3 0.1 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAK67583.1 - 0.0021 17.4 0.3 0.005 16.2 0.2 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 GAK67583.1 - 0.0053 16.2 0.1 2.6 7.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 GAK67583.1 - 0.0063 15.6 0.7 0.013 14.5 0.5 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 GAK67583.1 - 0.0079 15.3 0.1 0.46 9.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAK67583.1 - 0.013 14.8 0.1 0.038 13.3 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Chlorosome_CsmC PF11098.3 GAK67583.1 - 0.032 13.9 0.1 0.8 9.4 0.0 2.7 3 0 0 3 3 3 0 Chlorosome envelope protein C DUF2075 PF09848.4 GAK67583.1 - 0.049 12.6 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 GAK67583.1 - 0.056 13.1 0.2 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 NTPase DnaB_C PF03796.10 GAK67583.1 - 0.08 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Peroxin-3 PF04882.7 GAK67584.1 - 4.9e-130 434.1 0.0 1.3e-129 432.7 0.0 1.5 1 1 0 1 1 1 1 Peroxin-3 PAM2 PF07145.10 GAK67584.1 - 0.012 15.0 0.5 0.038 13.4 0.4 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region PAT1 PF09770.4 GAK67584.1 - 4.4 5.4 27.1 6.7 4.8 18.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ACBP PF00887.14 GAK67585.1 - 6.3e-28 96.2 0.0 1.1e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein SH3_9 PF14604.1 GAK67587.1 - 9.1e-08 31.5 0.0 1.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAK67587.1 - 7.1e-07 28.5 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAK67587.1 - 0.00033 20.0 0.0 0.00056 19.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MoCF_biosynth PF00994.19 GAK67588.1 - 1.7e-57 192.8 0.7 3.3e-28 97.8 0.1 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 GAK67588.1 - 3.6e-31 107.7 0.3 5.5e-31 107.0 0.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 GAK67588.1 - 5.1e-10 39.1 0.8 2e-09 37.2 0.1 2.5 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) DUF2946 PF11162.3 GAK67588.1 - 0.0057 16.8 5.7 0.024 14.8 3.9 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) FERM_M PF00373.13 GAK67589.1 - 0.024 14.8 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 FERM central domain Ank_2 PF12796.2 GAK67590.1 - 2.5e-21 75.8 2.3 2.4e-09 37.4 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAK67590.1 - 1.1e-19 70.3 2.5 9.9e-11 41.8 0.1 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 GAK67590.1 - 3.8e-18 64.2 0.0 5.7e-08 32.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 GAK67590.1 - 2.7e-16 58.0 0.4 3.1e-05 23.7 0.0 5.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAK67590.1 - 2.4e-15 56.2 1.1 8e-08 32.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.8 GAK67590.1 - 3.4e-06 26.6 0.1 2.4e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain ATP-synt_B PF00430.13 GAK67590.1 - 6.5 6.5 6.2 6.5 6.5 2.2 2.5 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) EMG1 PF03587.9 GAK67591.1 - 6.1e-76 254.2 0.0 8.6e-76 253.7 0.0 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Golgin_A5 PF09787.4 GAK67591.1 - 5.8 5.3 7.8 8.1 4.8 5.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 NUDIX PF00293.23 GAK67592.1 - 4.3e-17 62.0 0.0 8.2e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 GAK67592.1 - 1.2e-10 41.5 0.2 5.3e-10 39.5 0.3 2.0 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain 7TM_GPCR_Str PF10326.4 GAK67592.1 - 0.15 11.1 0.0 2.1 7.3 0.0 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str RRM_1 PF00076.17 GAK67593.1 - 3.6e-40 135.4 0.0 5e-21 74.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK67593.1 - 7.9e-34 115.4 0.0 1.3e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK67593.1 - 6.7e-17 61.0 0.0 2.7e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 GAK67593.1 - 0.071 11.5 36.9 0.097 11.1 25.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 2-Hacid_dh_C PF02826.14 GAK67595.1 - 6.9e-26 90.4 0.1 1.1e-24 86.5 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 GAK67595.1 - 0.022 13.8 0.2 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_18 PF00704.23 GAK67596.1 - 2.1e-64 218.1 1.5 2.6e-64 217.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_66 PF13199.1 GAK67596.1 - 0.02 13.3 0.0 0.033 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 UBA_e1_C PF09358.5 GAK67598.1 - 1.6e-43 147.8 0.1 3e-43 146.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain ThiF PF00899.16 GAK67598.1 - 7.5e-43 145.6 0.1 2.9e-28 98.3 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 GAK67598.1 - 8.1e-37 124.6 0.1 1.8e-25 88.2 0.0 2.9 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 GAK67598.1 - 4.4e-26 89.9 1.1 1.6e-22 78.5 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site DSPn PF14671.1 GAK67599.1 - 4.6e-35 120.6 0.0 5e-34 117.2 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half adh_short_C2 PF13561.1 GAK67599.1 - 4.6e-20 72.4 0.1 8.2e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK67599.1 - 4.3e-17 62.5 1.1 1.4e-16 60.9 0.8 1.9 1 0 0 1 1 1 1 short chain dehydrogenase DSPc PF00782.15 GAK67599.1 - 5.6e-13 48.6 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAK67599.1 - 0.00013 21.3 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAK67599.1 - 0.031 14.3 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Acyl-CoA_dh_1 PF00441.19 GAK67600.1 - 4.8e-46 156.5 3.9 4.8e-46 156.5 2.7 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAK67600.1 - 9.4e-26 90.6 0.3 3.4e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAK67600.1 - 1.5e-23 83.5 1.3 1.5e-23 83.5 0.9 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAK67600.1 - 7.1e-18 63.8 0.0 1.5e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Snf7 PF03357.16 GAK67600.1 - 0.0018 17.7 1.3 0.0037 16.6 0.9 1.4 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 GAK67600.1 - 0.067 12.9 0.2 4.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit tRNA-synt_2b PF00587.20 GAK67601.1 - 4.2e-28 98.0 0.0 5.9e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAK67601.1 - 0.00032 20.5 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain RRM_1 PF00076.17 GAK67602.1 - 3.4e-16 58.6 0.0 2.2e-06 27.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK67602.1 - 8e-15 54.5 0.0 1.8e-07 31.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK67602.1 - 0.12 12.2 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 GAK67602.1 - 4 5.7 46.5 0.1 11.0 17.6 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 MAM33 PF02330.11 GAK67603.1 - 2.5e-28 99.2 0.1 3.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein PITH PF06201.8 GAK67604.1 - 4.7e-30 104.3 0.0 9.5e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 PITH domain Sec63 PF02889.11 GAK67605.1 - 1.8e-37 129.2 0.0 3e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 GAK67605.1 - 5.9e-16 57.9 1.1 1.5e-15 56.6 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain DDOST_48kD PF03345.9 GAK67605.1 - 0.029 12.9 0.1 6.5 5.1 0.0 2.4 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta Abhydro_lipase PF04083.11 GAK67606.1 - 1.7e-16 59.3 0.0 3.4e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 GAK67606.1 - 0.0002 21.3 0.2 0.00049 20.0 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK67606.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK67606.1 - 0.0011 18.5 1.1 0.0029 17.1 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold PMT PF02366.13 GAK67607.1 - 1e-73 247.6 12.3 1e-73 247.6 8.5 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAK67607.1 - 1.4e-44 151.9 0.5 1.1e-43 148.9 0.4 2.2 1 1 0 1 1 1 1 MIR domain SNARE PF05739.14 GAK67608.1 - 2e-18 65.8 3.5 2e-18 65.8 2.4 2.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 GAK67608.1 - 2.5e-08 34.0 8.3 3e-07 30.5 0.0 2.9 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 GAK67608.1 - 0.019 14.5 3.0 0.019 14.4 0.4 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Aida_N PF08910.5 GAK67608.1 - 0.04 14.1 2.9 0.097 12.9 0.2 2.3 2 0 0 2 2 2 0 Aida N-terminus DUF4211 PF13926.1 GAK67609.1 - 5.6e-09 35.5 0.1 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Pox_A_type_inc PF04508.7 GAK67609.1 - 0.76 9.7 4.8 8.1 6.5 0.6 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2638 PF10937.3 GAK67610.1 - 5.9e-09 36.9 1.4 7.5e-09 36.5 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) NDUF_B7 PF05676.8 GAK67611.1 - 1.9e-28 97.6 1.6 2.2e-28 97.4 1.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 GAK67611.1 - 8.4e-05 22.2 1.0 0.00012 21.8 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CGI-121 PF08617.5 GAK67612.1 - 7.7e-41 139.4 0.0 1.1e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF2834 PF11196.3 GAK67613.1 - 6.2e-05 23.0 14.9 0.0063 16.6 1.1 4.4 4 0 0 4 4 4 3 Protein of unknown function (DUF2834) Strabismus PF06638.6 GAK67613.1 - 0.43 8.8 1.3 0.7 8.1 0.9 1.2 1 0 0 1 1 1 0 Strabismus protein PMI_typeI PF01238.16 GAK67614.1 - 8.5e-110 367.2 0.0 9.9e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 GAK67614.1 - 2.9e-06 26.6 0.0 0.00054 19.4 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.2 GAK67614.1 - 0.0013 18.3 0.1 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 Cupin Cupin_3 PF05899.7 GAK67614.1 - 0.025 13.9 0.4 0.053 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 GAK67614.1 - 0.03 13.7 0.1 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.14 GAK67614.1 - 0.17 11.5 0.1 38 3.9 0.0 3.4 4 0 0 4 4 4 0 AraC-like ligand binding domain UPF0278 PF08745.6 GAK67615.1 - 0.13 11.4 0.1 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 UPF0278 family XRN_N PF03159.13 GAK67616.1 - 3.8e-106 353.8 0.9 5.7e-106 353.2 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 GAK67616.1 - 0.00028 20.6 1.2 0.00064 19.5 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Vfa1 PF08432.5 GAK67617.1 - 2.5e-36 125.3 4.5 4.1e-36 124.7 3.1 1.3 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.1 GAK67617.1 - 0.012 15.0 1.7 0.02 14.3 1.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO GHMP_kinases_N PF00288.21 GAK67617.1 - 0.49 10.4 3.1 1.9 8.6 0.0 2.6 3 0 0 3 3 3 0 GHMP kinases N terminal domain DUF566 PF04484.7 GAK67617.1 - 0.64 9.4 8.3 0.81 9.1 5.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) AMP-binding PF00501.23 GAK67619.1 - 6.9e-85 284.9 0.0 9e-85 284.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK67619.1 - 6.3e-10 39.8 0.4 2.1e-09 38.1 0.3 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3671 PF12420.3 GAK67621.1 - 8.1 6.4 4.9 2.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function Translin PF01997.11 GAK67622.1 - 2.9e-49 167.3 0.6 6.4e-49 166.2 0.1 1.7 2 0 0 2 2 2 1 Translin family DinB_2 PF12867.2 GAK67623.1 - 0.0027 18.0 0.1 0.0044 17.3 0.1 1.4 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.7 GAK67623.1 - 0.034 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 DinB family DUF3931 PF13082.1 GAK67623.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) HMG_box PF00505.14 GAK67625.1 - 1.5e-15 57.2 2.1 3.7e-15 55.9 1.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAK67625.1 - 1.5e-11 44.4 1.1 2.9e-11 43.5 0.8 1.4 1 0 0 1 1 1 1 HMG-box domain DUF3479 PF11965.3 GAK67625.1 - 0.083 12.6 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) KfrA_N PF11740.3 GAK67625.1 - 0.15 12.5 0.0 0.15 12.5 0.0 2.2 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term zf-CCCH PF00642.19 GAK67626.1 - 0.0048 16.5 5.0 0.0087 15.7 3.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PBP1_TM PF14812.1 GAK67626.1 - 0.39 11.0 1.7 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2422 PF10337.4 GAK67627.1 - 1.4e-110 370.2 1.1 1.4e-110 370.2 0.8 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 GAK67627.1 - 7.3e-23 81.3 0.4 8.1e-12 45.2 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 GAK67627.1 - 1.3e-07 31.6 21.1 1.3e-07 31.6 14.6 4.1 2 2 2 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.3 GAK67627.1 - 0.2 10.2 0.0 0.2 10.2 0.0 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Pkinase PF00069.20 GAK67628.1 - 2e-70 236.9 0.0 3e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_3 PF07859.8 GAK67628.1 - 3.5e-48 163.9 0.6 2.6e-47 161.1 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.12 GAK67628.1 - 1.7e-34 119.0 0.0 2.4e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2424 PF10340.4 GAK67628.1 - 2.1e-12 46.3 0.0 6e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) YrbL-PhoP_reg PF10707.4 GAK67628.1 - 4.2e-07 29.4 0.0 7.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 GAK67628.1 - 0.0057 15.7 0.4 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family GlnD_UR_UTase PF08335.6 GAK67628.1 - 0.017 14.9 0.1 0.044 13.6 0.1 1.6 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase Kinase-like PF14531.1 GAK67628.1 - 0.044 12.7 0.0 0.56 9.1 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 GAK67628.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Na_H_Exchanger PF00999.16 GAK67629.1 - 3.5e-28 98.2 32.9 3e-15 55.6 4.0 2.3 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family YfhO PF09586.5 GAK67629.1 - 2 6.3 3.4 0.55 8.1 0.1 1.6 2 0 0 2 2 2 0 Bacterial membrane protein YfhO RTA1 PF04479.8 GAK67630.1 - 2.1e-34 118.9 3.1 2.7e-34 118.6 2.2 1.0 1 0 0 1 1 1 1 RTA1 like protein URO-D PF01208.12 GAK67631.1 - 2e-133 444.5 0.0 2.3e-133 444.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF1793 PF08760.6 GAK67632.1 - 8.3e-69 230.8 0.4 8.3e-69 230.8 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) RNA_pol_Rpb1_5 PF04998.12 GAK67633.1 - 9.7e-94 313.6 0.3 1.5e-93 313.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 GAK67633.1 - 2.7e-88 296.4 0.0 3.8e-88 295.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 GAK67633.1 - 1.8e-66 223.1 0.0 3.4e-66 222.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 FAA_hydrolase PF01557.13 GAK67633.1 - 1.5e-50 171.6 0.0 3.3e-50 170.5 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RNA_pol_Rpb1_3 PF04983.13 GAK67633.1 - 1e-36 126.0 0.0 3.9e-36 124.1 0.0 2.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 GAK67633.1 - 7.1e-31 106.1 0.0 1.6e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 GAK67633.1 - 0.029 13.8 0.1 0.081 12.4 0.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain Baculo_ME53 PF06061.6 GAK67633.1 - 0.032 13.2 0.1 0.059 12.3 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 DUF2225 PF09986.4 GAK67633.1 - 0.078 12.4 0.4 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) UNC45-central PF11701.3 GAK67634.1 - 2.2e-08 33.9 0.3 9.6e-08 31.8 0.2 2.1 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Bac_rhamnosid PF05592.6 GAK67635.1 - 4.7e-25 87.7 0.4 9.2e-18 63.7 0.2 3.1 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase Pyr_redox PF00070.22 GAK67636.1 - 4.9e-10 39.6 0.0 1.5e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAK67636.1 - 1.2e-08 35.1 0.0 2.2e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK67636.1 - 0.00066 19.7 0.4 1.3 9.0 0.1 3.4 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 GAK67637.1 - 1.6e-19 69.8 38.7 4.4e-17 61.8 11.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.7 GAK67637.1 - 0.0096 15.8 4.0 0.019 14.9 0.3 3.1 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 ABC_membrane PF00664.18 GAK67638.1 - 7e-59 199.4 24.5 1.1e-31 110.3 6.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAK67638.1 - 1.9e-49 167.4 0.1 1.4e-27 96.7 0.0 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAK67638.1 - 7.2e-10 38.4 0.0 3e-05 23.3 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 GAK67638.1 - 8.5e-09 34.7 0.1 0.0043 16.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAK67638.1 - 2.4e-06 26.9 1.3 0.046 13.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAK67638.1 - 1e-05 25.0 3.9 0.031 13.6 0.2 3.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 GAK67638.1 - 1.4e-05 25.1 5.7 0.012 15.5 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 GAK67638.1 - 2e-05 24.5 0.1 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 GAK67638.1 - 3.4e-05 24.3 1.9 0.021 15.3 0.1 2.8 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 GAK67638.1 - 5e-05 23.5 0.3 0.11 12.7 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAK67638.1 - 5.7e-05 22.1 0.1 0.098 11.5 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 GAK67638.1 - 0.0002 20.8 0.1 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 GAK67638.1 - 0.00033 20.8 1.4 0.13 12.3 0.4 3.1 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 GAK67638.1 - 0.00068 19.3 1.2 0.56 9.9 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 GAK67638.1 - 0.00095 18.0 1.8 0.076 11.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 GAK67638.1 - 0.0013 19.5 0.1 1.3 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAK67638.1 - 0.0019 18.0 3.6 0.59 10.0 1.1 3.3 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAK67638.1 - 0.0032 16.9 0.1 0.38 10.1 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 GAK67638.1 - 0.0039 16.7 6.0 0.11 12.0 0.4 3.2 3 1 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 GAK67638.1 - 0.0039 16.7 5.0 1.8 8.0 0.4 3.3 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 GAK67638.1 - 0.0049 17.0 0.7 1.2 9.3 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Zeta_toxin PF06414.7 GAK67638.1 - 0.0052 15.9 2.2 1.4 7.9 0.1 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.1 GAK67638.1 - 0.0067 16.4 0.1 15 5.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.12 GAK67638.1 - 0.014 14.8 2.3 6.7 6.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.8 GAK67638.1 - 0.018 13.9 1.7 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 GAK67638.1 - 0.033 12.8 2.8 1.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 GAK67638.1 - 0.04 13.5 1.2 3.1 7.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 GAK67638.1 - 0.044 13.7 0.8 0.41 10.6 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 GAK67638.1 - 0.05 13.4 7.3 0.22 11.3 0.2 2.8 3 0 0 3 3 2 0 Dynamin family UPF0079 PF02367.12 GAK67638.1 - 0.06 12.9 2.0 6.4 6.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 GAK67638.1 - 0.085 12.5 0.6 1.4 8.5 0.0 2.9 4 0 0 4 4 3 0 Archaeal ATPase AAA_23 PF13476.1 GAK67638.1 - 0.13 12.5 0.9 7.1 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain GTP_EFTU PF00009.22 GAK67638.1 - 0.15 11.4 1.0 14 5.0 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.12 GAK67638.1 - 0.21 11.3 11.1 0.14 11.9 0.3 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 ABC_ATPase PF09818.4 GAK67638.1 - 0.3 9.6 2.0 8.6 4.8 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 GAK67638.1 - 0.33 11.2 1.8 11 6.3 0.3 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAK67638.1 - 0.97 9.3 6.6 2 8.3 0.3 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 GAK67638.1 - 1.4 8.3 5.5 7.1 6.0 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.14 GAK67638.1 - 2.8 7.3 7.6 8.3 5.8 0.3 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 GAK67638.1 - 6.5 6.4 6.7 2.2 7.9 0.1 2.9 3 0 0 3 3 3 0 NTPase Acetyltransf_8 PF13523.1 GAK67639.1 - 2.7e-25 89.0 0.0 7.4e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH PF00378.15 GAK67640.1 - 5.5e-58 195.9 0.0 7.1e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding PF00501.23 GAK67641.1 - 6.9e-219 726.3 1.9 8.7e-76 254.9 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAK67641.1 - 3e-149 495.8 0.3 1.4e-38 132.4 0.1 6.3 6 2 0 6 6 6 5 Condensation domain PP-binding PF00550.20 GAK67641.1 - 8.9e-39 131.6 3.6 6.2e-09 35.9 0.1 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAK67641.1 - 4.6e-15 56.3 0.1 4.1e-07 30.8 0.0 4.3 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain AATase PF07247.7 GAK67641.1 - 0.0012 17.4 0.0 7.7 4.9 0.0 4.6 5 0 0 5 5 5 2 Alcohol acetyltransferase DUF2306 PF10067.4 GAK67642.1 - 0.00087 19.3 14.2 0.0022 18.0 1.7 4.0 4 1 1 5 5 5 2 Predicted membrane protein (DUF2306) PepSY_TM_2 PF13703.1 GAK67642.1 - 0.049 13.8 7.6 3.6 7.8 0.1 3.6 3 0 0 3 3 3 0 PepSY-associated TM helix DUF420 PF04238.7 GAK67642.1 - 0.14 12.1 1.7 10 6.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF420) PepSY_TM_1 PF13172.1 GAK67642.1 - 4.3 7.2 12.3 6.3 6.6 1.2 3.9 3 0 0 3 3 3 0 PepSY-associated TM helix LigB PF02900.13 GAK67645.1 - 3.7e-24 85.1 0.1 3.9e-23 81.8 0.1 2.1 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase ABC1 PF03109.11 GAK67646.1 - 1e-30 106.1 0.2 2e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 GAK67646.1 - 0.0058 16.0 0.1 0.016 14.5 0.0 1.8 1 1 0 1 1 1 1 RIO1 family MFS_1 PF07690.11 GAK67647.1 - 2.4e-43 148.2 24.0 2.4e-43 148.2 16.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK67647.1 - 1.5e-15 56.7 13.5 3.7e-15 55.4 9.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 GAK67647.1 - 0.0012 17.0 5.2 0.14 10.2 3.6 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_2 PF00890.19 GAK67648.1 - 5.5e-89 298.8 0.1 5.5e-89 298.8 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.23 GAK67648.1 - 5.9e-21 74.0 0.1 1.8e-20 72.4 0.1 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 GAK67648.1 - 3e-14 52.7 0.8 2.4e-13 49.7 0.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK67648.1 - 6.8e-11 42.0 0.2 6.6e-10 38.8 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK67648.1 - 1e-10 41.8 0.0 1e-08 35.3 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAK67648.1 - 4.1e-09 36.0 0.2 8.1e-09 35.0 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK67648.1 - 6.6e-07 28.1 2.9 0.00011 20.8 0.1 3.1 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 GAK67648.1 - 6.9e-07 28.4 0.9 0.0047 15.8 0.3 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.12 GAK67648.1 - 3.6e-06 26.2 0.4 0.00094 18.3 0.2 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 GAK67648.1 - 1e-05 24.7 2.1 4e-05 22.8 1.5 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAK67648.1 - 2.9e-05 24.2 1.2 9.5e-05 22.5 0.1 2.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAK67648.1 - 3.7e-05 23.0 0.0 0.003 16.7 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAK67648.1 - 8.9e-05 22.8 0.9 0.0016 18.8 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAK67648.1 - 0.0049 16.4 0.1 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 GAK67648.1 - 0.009 15.7 0.3 0.093 12.5 0.2 2.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 GAK67648.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 GAK67648.1 - 0.02 13.8 0.2 0.04 12.8 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.13 GAK67648.1 - 0.037 12.3 0.0 0.06 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Nfu_N PF08712.6 GAK67649.1 - 5.9e-32 109.1 0.0 1.2e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 GAK67649.1 - 1.6e-21 75.7 0.1 3.5e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain DUF3295 PF11702.3 GAK67649.1 - 3.2 6.6 8.2 0.79 8.6 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3295) ECH PF00378.15 GAK67650.1 - 4.2e-79 265.1 2.2 5.4e-79 264.7 1.5 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAK67650.1 - 8.2e-05 22.4 0.3 0.045 13.5 0.0 2.8 2 2 0 2 2 2 2 Peptidase family S49 ECH_C PF13766.1 GAK67650.1 - 0.036 14.2 0.5 0.18 11.9 0.1 2.0 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Spc97_Spc98 PF04130.8 GAK67652.1 - 9.4e-64 215.6 0.0 1.5e-63 214.9 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DNA_pol_E_B PF04042.11 GAK67653.1 - 3.1e-40 137.6 0.0 6.1e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF572 PF04502.8 GAK67655.1 - 1.6e-81 274.0 7.6 3e-81 273.1 5.2 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) TOM20_plant PF06552.7 GAK67655.1 - 0.025 14.1 0.4 1.6 8.3 0.2 2.2 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Benyvirus_14KDa PF07255.6 GAK67655.1 - 0.059 13.2 0.3 0.56 10.0 0.0 2.1 1 1 1 2 2 2 0 Benyvirus 14KDa protein Ribosomal_60s PF00428.14 GAK67655.1 - 0.93 9.9 20.9 0.42 11.0 0.7 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein MARVEL PF01284.18 GAK67656.1 - 0.016 14.9 13.0 0.029 14.1 7.6 2.2 1 1 1 2 2 2 0 Membrane-associating domain DUF2583 PF10762.4 GAK67656.1 - 0.088 12.9 0.3 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) RAB3GAP2_N PF14655.1 GAK67657.1 - 0.048 12.6 4.8 0.057 12.4 3.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.3 GAK67657.1 - 0.09 12.1 3.6 0.11 11.8 2.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF4175 PF13779.1 GAK67657.1 - 0.34 8.5 11.5 0.4 8.3 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PNRC PF15365.1 GAK67657.1 - 0.47 10.5 0.3 0.47 10.5 0.2 2.4 2 1 0 2 2 2 0 Proline-rich nuclear receptor coactivator Suf PF05843.9 GAK67657.1 - 0.61 9.7 3.9 0.63 9.7 2.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TSA PF03249.8 GAK67657.1 - 2.2 6.7 13.6 2.5 6.5 9.4 1.0 1 0 0 1 1 1 0 Type specific antigen CRAL_TRIO PF00650.15 GAK67658.1 - 8.5e-41 139.0 0.0 1.3e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Hydrolase_6 PF13344.1 GAK67658.1 - 9.5e-29 99.2 0.0 1.9e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAK67658.1 - 8.7e-18 63.8 0.0 3.1e-17 62.0 0.0 2.0 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAK67658.1 - 4.1e-14 53.4 0.0 1.2e-13 51.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CRAL_TRIO_2 PF13716.1 GAK67658.1 - 7.4e-13 48.6 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HAD_2 PF13419.1 GAK67658.1 - 1.2e-05 25.5 1.9 0.039 14.1 0.1 3.1 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase CRAL_TRIO_N PF03765.10 GAK67658.1 - 1.4e-05 25.1 0.1 4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PGP_phosphatase PF09419.5 GAK67658.1 - 0.13 11.5 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DFF40 PF09230.5 GAK67659.1 - 0.091 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa CMD PF02627.15 GAK67660.1 - 3e-10 39.8 0.3 5.2e-09 35.8 0.1 2.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Mito_carr PF00153.22 GAK67661.1 - 1.4e-53 178.5 4.7 2.1e-18 65.7 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein PGM_PMM_I PF02878.11 GAK67663.1 - 8.6e-20 70.6 0.1 3.3e-10 39.5 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAK67663.1 - 1.1e-11 44.9 0.0 7.3e-11 42.3 0.0 2.4 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAK67663.1 - 3.1e-08 33.4 0.0 7.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 GAK67663.1 - 0.014 15.3 0.1 0.061 13.3 0.0 1.9 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ORMDL PF04061.9 GAK67664.1 - 1.3e-56 189.9 2.4 1.6e-56 189.6 1.7 1.1 1 0 0 1 1 1 1 ORMDL family DUF663 PF04950.7 GAK67665.1 - 1.7e-88 296.4 0.0 3.1e-88 295.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAK67665.1 - 4e-22 77.5 0.0 9e-22 76.4 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain eIF_4EBP PF05456.6 GAK67666.1 - 4.3e-13 48.9 0.4 4.7e-13 48.8 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Mito_carr PF00153.22 GAK67667.1 - 1.4e-66 220.1 0.3 6.1e-26 89.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad52_Rad22 PF04098.10 GAK67668.1 - 4.6e-57 192.0 0.1 2.2e-56 189.8 0.0 1.9 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein Pkinase PF00069.20 GAK67669.1 - 7.9e-70 234.9 0.0 1.6e-69 233.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67669.1 - 2.2e-37 128.5 0.0 6.3e-37 127.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK67669.1 - 2.3e-07 30.0 0.0 4.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 GAK67669.1 - 0.00033 20.0 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 GAK67669.1 - 0.013 14.8 0.3 0.031 13.6 0.2 1.5 1 0 0 1 1 1 0 RIO1 family DUF1687 PF07955.6 GAK67670.1 - 8.8e-08 32.2 0.0 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1687) F-box PF00646.28 GAK67671.1 - 2.2e-08 33.5 0.4 4.9e-08 32.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAK67671.1 - 4.2e-05 23.1 5.4 0.00011 21.8 3.7 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 GAK67671.1 - 0.015 15.1 0.0 3.2 7.7 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat DDOST_48kD PF03345.9 GAK67672.1 - 8.3e-101 337.5 0.0 5.4e-63 212.9 0.0 2.1 1 1 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta Gly_radical PF01228.16 GAK67672.1 - 0.0048 17.2 0.0 0.018 15.3 0.0 2.0 1 0 0 1 1 1 1 Glycine radical SynMuv_product PF06047.6 GAK67673.1 - 1.2e-50 169.6 1.6 3.2e-50 168.2 1.1 1.8 1 0 0 1 1 1 1 Ras-induced vulval development antagonist ATP_bind_4 PF01902.12 GAK67674.1 - 1.1e-39 136.0 0.0 4.1e-28 98.2 0.0 2.3 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 GAK67674.1 - 2.5e-15 56.3 0.0 3.4e-08 33.2 0.0 2.7 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.11 GAK67674.1 - 0.05 12.1 0.0 0.086 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Adeno_E3 PF06040.6 GAK67674.1 - 0.27 11.1 0.8 17 5.4 0.0 2.8 3 0 0 3 3 3 0 Adenovirus E3 protein SUV3_C PF12513.3 GAK67675.1 - 4.2e-13 48.4 0.1 8.9e-13 47.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 GAK67675.1 - 6.4e-12 45.1 0.0 1.7e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_4 PF13871.1 GAK67675.1 - 0.03 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase_C-like LrgB PF04172.11 GAK67676.1 - 9.7e-20 70.6 8.7 9.7e-20 70.6 6.0 2.7 3 1 0 3 3 3 1 LrgB-like family LrgA PF03788.9 GAK67676.1 - 0.00031 20.3 3.1 0.00031 20.3 2.1 3.0 3 1 0 3 3 3 1 LrgA family Myc_N PF01056.13 GAK67676.1 - 0.0024 17.1 5.2 0.0037 16.4 3.6 1.2 1 0 0 1 1 1 1 Myc amino-terminal region PAT1 PF09770.4 GAK67676.1 - 0.37 8.9 9.0 0.51 8.5 6.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 GAK67676.1 - 0.73 9.1 6.2 10 5.3 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PAS PF00989.19 GAK67677.1 - 0.17 11.6 0.1 0.49 10.1 0.0 1.7 2 0 0 2 2 2 0 PAS fold LCM PF04072.9 GAK67679.1 - 1.5e-18 67.0 0.0 2.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Scs3p PF10261.4 GAK67680.1 - 3.1e-62 209.7 0.5 3.8e-62 209.4 0.3 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Ribosomal_S17 PF00366.15 GAK67682.1 - 3.5e-16 58.9 2.7 4.5e-16 58.6 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S17 B-block_TFIIIC PF04182.7 GAK67683.1 - 1.9e-13 50.0 0.0 6.8e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC F-box-like PF12937.2 GAK67684.1 - 6.6e-10 38.5 0.6 1.5e-09 37.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 GAK67684.1 - 7e-07 28.8 0.2 0.059 13.2 0.0 3.2 2 1 0 2 2 2 2 WD domain, G-beta repeat F-box PF00646.28 GAK67684.1 - 3e-06 26.7 0.1 1e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 F-box domain Ribosomal_L28e PF01778.12 GAK67685.1 - 3.7e-31 107.9 2.1 3.7e-31 107.9 1.4 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family CD99L2 PF12301.3 GAK67685.1 - 0.047 13.3 0.1 6.4 6.4 0.0 2.3 1 1 1 2 2 2 0 CD99 antigen like protein 2 Hydrophobin PF01185.13 GAK67686.1 - 3.9e-16 59.2 12.0 4.9e-16 58.9 8.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_9 PF02819.10 GAK67686.1 - 2.1 8.5 7.5 4.1 7.5 0.5 2.3 2 0 0 2 2 2 0 Spider toxin Toxin_12 PF07740.7 GAK67686.1 - 5.2 7.6 6.8 2.2 8.8 0.5 2.5 2 0 0 2 2 2 0 Ion channel inhibitory toxin ApoO PF09769.4 GAK67687.1 - 4.6e-32 110.9 1.2 4.6e-32 110.9 0.8 1.8 2 0 0 2 2 2 1 Apolipoprotein O ATP-synt_B PF00430.13 GAK67687.1 - 0.43 10.3 4.3 0.47 10.2 2.1 1.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF972 PF06156.8 GAK67688.1 - 0.015 15.6 5.6 0.033 14.5 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Med9 PF07544.8 GAK67688.1 - 0.03 14.0 7.1 0.084 12.6 4.9 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Mod_r PF07200.8 GAK67688.1 - 0.15 11.9 8.2 0.27 11.1 5.7 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.6 GAK67688.1 - 0.33 9.5 5.7 0.42 9.2 3.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) IncA PF04156.9 GAK67688.1 - 0.66 9.5 9.5 1.2 8.7 6.6 1.3 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 GAK67688.1 - 7.6 6.4 13.1 0.048 13.4 1.0 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Mnd1 PF03962.10 GAK67688.1 - 9.2 5.8 11.7 11 5.5 7.7 1.4 1 1 0 1 1 1 0 Mnd1 family PAP_assoc PF03828.14 GAK67690.1 - 1.1e-14 54.0 0.1 2.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAK67690.1 - 7.1e-05 23.0 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.20 GAK67691.1 - 5.9e-50 169.8 0.0 8.4e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67691.1 - 8.5e-35 120.0 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAK67691.1 - 6.7e-08 32.8 0.0 2.8e-07 30.8 0.0 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 GAK67691.1 - 0.00027 20.0 0.0 0.00062 18.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 GAK67691.1 - 1 8.0 0.0 1.6 7.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 UBA_4 PF14555.1 GAK67694.1 - 2e-10 40.0 0.0 4.9e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.15 GAK67694.1 - 3.8e-06 25.9 9.3 0.0094 15.4 1.0 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif UCH PF00443.24 GAK67694.1 - 0.02 14.0 0.0 0.22 10.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 GAK67694.1 - 0.088 12.6 0.1 4.3 7.3 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain S4 PF01479.20 GAK67695.1 - 1.4e-12 46.8 0.0 2.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 GAK67695.1 - 0.038 13.5 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 S4 domain JSRP PF15312.1 GAK67695.1 - 0.16 11.9 1.3 0.61 10.0 0.9 2.0 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Rtf2 PF04641.7 GAK67695.1 - 0.57 9.3 6.6 0.96 8.5 4.6 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Sigma70_ner PF04546.8 GAK67695.1 - 3.1 7.3 12.0 5 6.6 8.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region S-AdoMet_synt_C PF02773.11 GAK67696.1 - 6.2e-74 246.2 0.5 1.1e-73 245.4 0.3 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 GAK67696.1 - 3.2e-48 162.6 0.0 6.3e-48 161.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 GAK67696.1 - 6.7e-44 148.1 0.2 6.7e-44 148.1 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain MFS_1 PF07690.11 GAK67697.1 - 1.7e-37 129.0 53.9 2.2e-24 85.8 18.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.17 GAK67698.1 - 7.8e-23 80.7 0.0 1.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 GAK67699.1 - 1e-13 50.7 42.7 1.1e-13 50.6 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.16 GAK67700.1 - 6.6e-115 384.1 48.3 7.9e-115 383.9 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAK67700.1 - 1.3e-32 112.9 52.4 1.9e-32 112.3 36.2 1.3 1 1 0 1 1 1 1 Amino acid permease ALS_ss_C PF10369.4 GAK67701.1 - 3.7e-22 77.8 0.1 1.7e-19 69.3 0.0 2.4 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 GAK67701.1 - 1.2e-11 43.8 0.0 2.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 GAK67701.1 - 7.7e-08 32.0 0.1 3e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 ACT domain Pkinase PF00069.20 GAK67703.1 - 3.1e-57 193.6 0.0 3.2e-56 190.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67703.1 - 2.1e-27 95.8 0.0 1.1e-26 93.4 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.1 GAK67703.1 - 2.8e-06 27.1 0.0 2.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 PH domain Kdo PF06293.9 GAK67703.1 - 1.8e-05 23.9 0.0 3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAK67703.1 - 2.6e-05 23.3 0.0 4.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK67703.1 - 0.0039 16.9 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sec_GG PF07549.9 GAK67703.1 - 0.12 11.6 0.1 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif Sugar_tr PF00083.19 GAK67704.1 - 4.4e-126 421.0 25.0 5.1e-126 420.8 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK67704.1 - 4.4e-24 84.8 39.5 8.8e-19 67.4 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.7 GAK67705.1 - 0.00015 22.1 0.0 0.00074 19.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK67705.1 - 0.00025 21.6 0.2 0.0069 16.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK67705.1 - 0.024 14.3 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAK67705.1 - 0.026 14.1 0.0 0.097 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 GAK67705.1 - 0.049 13.9 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 GAK67706.1 - 5.6e-16 57.7 7.7 6.8e-06 25.7 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nop14 PF04147.7 GAK67707.1 - 0.00069 17.6 31.3 0.0013 16.8 21.7 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 GAK67707.1 - 0.063 12.5 28.4 0.12 11.6 19.7 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 GAK67707.1 - 0.13 10.2 22.7 0.21 9.5 15.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 GAK67707.1 - 1.6 6.3 2.6 2.1 5.9 1.8 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 GAK67707.1 - 4.2 5.8 9.2 6.9 5.1 6.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.8 GAK67707.1 - 4.2 7.1 47.0 0.066 13.1 26.1 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.9 GAK67707.1 - 9.5 5.6 18.3 19 4.6 12.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_L1 PF00687.16 GAK67708.1 - 9.5e-53 178.7 5.0 1.1e-52 178.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Band_7 PF01145.20 GAK67709.1 - 1.6e-21 77.0 0.4 2.4e-21 76.4 0.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Actin PF00022.14 GAK67710.1 - 4.1e-34 117.6 0.0 4.3e-33 114.2 0.0 2.3 1 1 0 1 1 1 1 Actin AAA_12 PF13087.1 GAK67711.1 - 3.5e-45 153.8 0.0 7.4e-45 152.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain Dna2 PF08696.6 GAK67711.1 - 1.1e-41 142.4 0.1 4.4e-18 65.3 0.0 3.3 3 0 0 3 3 3 3 DNA replication factor Dna2 AAA_11 PF13086.1 GAK67711.1 - 4.5e-38 131.1 0.0 1.6e-18 67.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 GAK67711.1 - 4.8e-14 52.4 0.0 9.1e-13 48.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAK67711.1 - 2.3e-11 43.2 1.6 1.8e-10 40.3 0.1 2.9 2 1 1 3 3 2 1 Part of AAA domain PDDEXK_1 PF12705.2 GAK67711.1 - 1.8e-06 27.5 0.0 5.9e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Helicase_RecD PF05127.9 GAK67711.1 - 7.7e-06 25.6 0.1 6e-05 22.7 0.0 2.5 2 1 0 2 2 1 1 Helicase AAA_16 PF13191.1 GAK67711.1 - 1.4e-05 25.1 0.5 0.00072 19.5 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 GAK67711.1 - 8.4e-05 22.2 0.1 0.18 11.3 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 GAK67711.1 - 0.00021 20.7 0.1 0.0004 19.8 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 GAK67711.1 - 0.00026 20.4 0.0 0.00065 19.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.16 GAK67711.1 - 0.00042 19.7 0.0 0.00086 18.6 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain MobB PF03205.9 GAK67711.1 - 0.0045 16.6 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 GAK67711.1 - 0.0073 15.2 0.1 0.017 14.0 0.1 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 GAK67711.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 GAK67711.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Cas_Cas4 PF01930.12 GAK67711.1 - 0.02 14.8 0.8 0.057 13.3 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function DUF83 ArgK PF03308.11 GAK67711.1 - 0.024 13.3 0.0 0.046 12.4 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 GAK67711.1 - 0.037 14.1 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 GAK67711.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 GAK67711.1 - 0.048 13.6 0.8 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 GAK67711.1 - 0.072 12.4 1.7 0.19 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain UvrD_C PF13361.1 GAK67711.1 - 0.072 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 GAK67711.1 - 0.081 11.8 0.0 0.16 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 GAK67711.1 - 0.093 12.1 0.1 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain PIF1 PF05970.9 GAK67711.1 - 0.35 9.7 0.0 4.6 6.0 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase CytochromB561_N PF09786.4 GAK67712.1 - 0.19 10.1 15.5 0.3 9.4 10.8 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal E1-E2_ATPase PF00122.15 GAK67713.1 - 6.3e-52 175.9 9.2 1.4e-51 174.8 6.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAK67713.1 - 4.5e-37 127.3 14.5 1.8e-35 122.1 2.1 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAK67713.1 - 1.3e-30 107.3 0.0 5.3e-30 105.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK67713.1 - 9.1e-15 53.8 0.0 2e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAK67713.1 - 1.8e-13 51.0 0.4 1.1e-12 48.5 0.0 2.5 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK67713.1 - 4.9e-09 36.0 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAK67713.1 - 0.00019 21.1 0.1 0.00038 20.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4149 PF13664.1 GAK67713.1 - 0.0025 17.8 5.4 0.032 14.2 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF4270 PF14092.1 GAK67713.1 - 0.065 11.8 0.0 0.097 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) DUF4411 PF14367.1 GAK67713.1 - 0.13 11.9 0.1 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) DUF2231 PF09990.4 GAK67713.1 - 3 8.2 11.4 2.4 8.5 1.0 4.0 4 0 0 4 4 4 0 Predicted membrane protein (DUF2231) Ins_P5_2-kin PF06090.7 GAK67714.1 - 5.2e-51 173.5 0.0 6.2e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Cmc1 PF08583.5 GAK67715.1 - 1.3e-16 60.0 4.6 1.7e-16 59.7 3.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 GAK67715.1 - 0.00037 20.4 2.6 0.22 11.5 0.4 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 GAK67715.1 - 0.04 13.8 4.1 0.11 12.4 0.6 2.3 2 0 0 2 2 2 0 CHCH domain NDUF_B7 PF05676.8 GAK67715.1 - 0.11 11.9 1.1 0.18 11.2 0.8 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ribosomal_S3Ae PF01015.13 GAK67716.1 - 4.2e-82 274.1 3.7 5.2e-82 273.8 2.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 GAK67716.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ribosomal_S7e PF01251.13 GAK67718.1 - 2.2e-84 281.6 0.5 2.4e-84 281.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RasGAP PF00616.14 GAK67719.1 - 2.5e-27 95.8 0.0 5.4e-27 94.7 0.0 1.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Glyoxalase_3 PF13468.1 GAK67720.1 - 6.3e-26 91.3 0.0 1.2e-24 87.1 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase-like domain GYF PF02213.11 GAK67721.1 - 0.00048 19.6 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 GYF domain Pkinase PF00069.20 GAK67722.1 - 6.5e-64 215.5 0.0 2.9e-38 131.5 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67722.1 - 5.2e-36 124.0 0.0 6e-18 64.8 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 GAK67722.1 - 5.6e-18 65.0 0.1 5.6e-18 65.0 0.1 1.9 3 0 0 3 3 3 1 Histidyl-tRNA synthetase RWD PF05773.17 GAK67722.1 - 5.8e-13 48.7 0.0 1.2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.2 GAK67722.1 - 1.5e-09 37.3 5.3 2.6e-09 36.6 0.0 2.9 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Kinase-like PF14531.1 GAK67722.1 - 1.2e-06 27.7 0.0 0.0063 15.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAK67722.1 - 0.00095 18.9 3.6 0.0069 16.1 0.0 3.7 4 0 0 4 4 4 1 Phosphotransferase enzyme family CENP-B_dimeris PF09026.5 GAK67722.1 - 0.21 11.8 8.1 0.28 11.4 0.7 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ycf1 PF05758.7 GAK67722.1 - 0.27 8.8 0.9 0.38 8.4 0.6 1.1 1 0 0 1 1 1 0 Ycf1 DPBB_1 PF03330.13 GAK67723.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4243 PF14027.1 GAK67724.1 - 1.3e-68 231.8 5.4 2e-68 231.2 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3140 PF11338.3 GAK67725.1 - 6.6e-31 106.2 3.8 6.6e-31 106.2 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3140) Med22 PF06179.7 GAK67725.1 - 1.8e-09 37.5 1.5 1.8e-09 37.5 1.0 2.4 3 0 0 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3237 PF11578.3 GAK67726.1 - 3.2e-35 120.6 0.2 3.6e-35 120.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF167 PF02594.11 GAK67726.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 Zn_clus PF00172.13 GAK67727.1 - 2.2e-05 24.2 9.9 4.4e-05 23.2 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.10 GAK67728.1 - 1.2e-51 175.4 0.7 1e-25 90.7 0.0 3.7 2 2 1 3 3 3 2 Hypothetical methyltransferase Methyltransf_23 PF13489.1 GAK67728.1 - 2.6e-05 23.9 0.0 0.00064 19.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK67728.1 - 0.0019 18.6 0.1 0.031 14.7 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain NARP1 PF12569.3 GAK67728.1 - 5.5 5.6 10.8 1.8 7.2 5.3 1.7 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 DUF3275 PF11679.3 GAK67729.1 - 0.016 14.8 0.1 0.016 14.8 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF3275) Trp_repressor PF01371.14 GAK67729.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Trp repressor protein DUF924 PF06041.6 GAK67730.1 - 9.8e-49 165.6 0.7 1.3e-48 165.2 0.5 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Fork_head PF00250.13 GAK67731.1 - 2.8e-15 56.1 0.0 5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 GAK67731.1 - 0.24 11.5 0.0 2.7 8.1 0.0 2.3 1 1 0 1 1 1 0 FHA domain CDC45 PF02724.9 GAK67731.1 - 5.3 4.9 20.9 9.3 4.1 14.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.4 GAK67731.1 - 7.8 5.2 8.6 18 4.0 5.9 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ytp1 PF10355.4 GAK67734.1 - 2.6e-99 331.8 2.9 2.6e-99 331.8 2.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAK67734.1 - 8.7e-25 86.3 0.4 8.7e-25 86.3 0.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Abhydrolase_3 PF07859.8 GAK67735.1 - 8.8e-23 80.9 0.2 3e-22 79.2 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAK67735.1 - 2.6e-13 49.3 0.0 1e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) COesterase PF00135.23 GAK67735.1 - 0.017 13.8 0.0 0.23 10.1 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family SSB PF00436.20 GAK67736.1 - 5.3e-14 51.9 0.0 6.6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Aminotran_1_2 PF00155.16 GAK67737.1 - 4.2e-74 249.6 0.0 7.1e-74 248.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAK67737.1 - 7.5e-08 31.5 0.0 1.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAK67737.1 - 7.8e-05 21.1 0.0 0.00024 19.5 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 GAK67737.1 - 0.0042 16.2 0.4 0.011 14.8 0.2 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Preseq_ALAS PF09029.5 GAK67737.1 - 0.0097 15.8 1.2 0.025 14.5 0.9 1.7 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence DegT_DnrJ_EryC1 PF01041.12 GAK67737.1 - 0.013 14.6 0.1 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L12 PF00542.14 GAK67738.1 - 7.6e-19 67.4 10.3 1.9e-18 66.1 3.0 2.3 2 1 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 GAK67738.1 - 0.0087 16.4 8.5 0.0087 16.4 5.9 2.3 2 1 0 2 2 2 1 60s Acidic ribosomal protein DAO PF01266.19 GAK67739.1 - 5.5e-48 163.6 0.1 6.5e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAK67739.1 - 0.0012 19.2 0.1 0.0073 16.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK67739.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAK67739.1 - 0.0045 15.9 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAK67739.1 - 0.005 16.9 0.0 0.016 15.2 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAK67739.1 - 0.0054 15.6 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAK67739.1 - 0.013 14.6 0.1 0.051 12.6 0.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Mqo PF06039.10 GAK67739.1 - 0.02 13.0 0.0 0.041 12.0 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.13 GAK67739.1 - 0.12 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 GAK67739.1 - 0.12 11.4 0.1 0.54 9.3 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Lactate_perm PF02652.9 GAK67739.1 - 0.15 10.5 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 L-lactate permease Snf7 PF03357.16 GAK67740.1 - 1.1e-42 145.3 17.4 1.1e-42 145.3 12.1 2.0 1 1 1 2 2 2 1 Snf7 Atg14 PF10186.4 GAK67740.1 - 0.0051 15.7 6.5 0.0051 15.7 4.5 1.5 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Sfi1_C PF10638.4 GAK67740.1 - 0.043 14.2 1.9 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Spindle body associated protein C-terminus SBDS_C PF09377.5 GAK67740.1 - 0.13 11.9 1.7 0.31 10.7 1.2 1.7 1 1 0 1 1 1 0 SBDS protein C-terminal domain Birna_RdRp PF04197.7 GAK67740.1 - 0.23 9.4 5.6 0.25 9.3 3.9 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) MxiH PF09392.5 GAK67740.1 - 0.66 10.5 5.6 6 7.5 3.9 2.5 1 1 0 1 1 1 0 Type III secretion needle MxiH like Ribosomal_60s PF00428.14 GAK67740.1 - 0.78 10.1 9.2 1.2 9.6 1.6 2.7 2 1 1 3 3 3 0 60s Acidic ribosomal protein DUF2450 PF10475.4 GAK67740.1 - 1.7 7.5 7.3 3.9 6.2 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DUF724 PF05266.9 GAK67740.1 - 1.8 8.1 10.1 0.79 9.3 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2229 PF09989.4 GAK67740.1 - 3 7.2 6.0 2.6 7.4 2.7 1.8 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) TMCO5 PF14992.1 GAK67740.1 - 6 5.9 12.3 11 5.0 8.5 1.5 1 1 0 1 1 1 0 TMCO5 family RasGEF PF00617.14 GAK67741.1 - 1e-51 175.3 0.0 1.6e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAK67741.1 - 1.9e-16 60.0 0.2 5.6e-16 58.5 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif MCM PF00493.18 GAK67742.1 - 9.8e-142 471.6 0.1 1.2e-141 471.2 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAK67742.1 - 9.3e-18 64.8 0.0 2.6e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAK67742.1 - 1.7e-06 27.3 0.0 0.00079 18.6 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAK67742.1 - 0.00016 21.3 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAK67742.1 - 0.0015 18.1 0.1 0.0096 15.5 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 GAK67742.1 - 0.0092 16.3 0.2 0.027 14.8 0.1 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAK67742.1 - 0.061 12.8 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TIG PF01833.19 GAK67743.1 - 2.2e-12 46.7 4.2 9.2e-12 44.7 2.9 2.1 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 GAK67743.1 - 4.2e-12 45.2 0.6 4.1e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAK67743.1 - 4.7e-12 46.0 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAK67743.1 - 2.3e-09 37.2 1.7 7.4e-09 35.5 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK67743.1 - 1.5e-07 30.9 0.2 0.0074 16.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAK67743.1 - 3.1e-07 30.7 0.9 4e-06 27.2 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Glyco_transf_17 PF04724.8 GAK67744.1 - 1.6e-86 290.5 0.0 1.9e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 SnoaL_4 PF13577.1 GAK67745.1 - 8.5e-09 35.3 0.2 1.9e-08 34.2 0.2 1.6 1 1 0 1 1 1 1 SnoaL-like domain PALP PF00291.20 GAK67746.1 - 1.3e-26 93.5 0.0 2.1e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 GAK67747.1 - 4.5e-45 153.8 61.1 1.1e-37 129.6 29.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAK67747.1 - 5.5e-21 74.4 19.6 7.2e-21 74.0 13.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAK67747.1 - 8.7e-15 54.2 8.4 8.7e-15 54.2 5.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Tfb2 PF03849.9 GAK67750.1 - 5.4e-145 482.6 0.0 6.6e-145 482.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 GAK67750.1 - 0.00025 20.8 0.1 0.0014 18.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Diphthamide_syn PF01866.12 GAK67751.1 - 1.6e-57 195.0 0.0 2e-36 125.8 0.0 2.2 2 0 0 2 2 2 2 Putative diphthamide synthesis protein VIT1 PF01988.14 GAK67752.1 - 2e-78 262.7 3.1 2.7e-78 262.3 2.1 1.2 1 0 0 1 1 1 1 VIT family RecX PF02631.11 GAK67752.1 - 0.0022 18.1 1.2 0.0038 17.4 0.9 1.3 1 0 0 1 1 1 1 RecX family HemX PF04375.9 GAK67752.1 - 0.019 13.5 4.0 0.04 12.5 2.8 1.5 1 0 0 1 1 1 0 HemX MRC1 PF09444.5 GAK67753.1 - 1.6e-30 106.3 22.3 1.6e-30 106.3 15.4 5.7 5 1 0 5 5 5 1 MRC1-like domain RAMP4 PF06624.7 GAK67753.1 - 0.006 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Mito_carr PF00153.22 GAK67755.1 - 1.3e-63 210.6 0.2 2.3e-21 75.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_22 PF03901.12 GAK67756.1 - 4.5e-70 236.7 0.0 6.8e-53 180.1 0.0 3.0 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family WD40 PF00400.27 GAK67757.1 - 5.4e-15 54.6 6.0 4.7e-06 26.2 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Vps26 PF03643.10 GAK67759.1 - 2.6e-131 436.4 4.3 3e-131 436.2 3.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 GAK67759.1 - 0.0037 17.1 2.0 1.1 9.0 0.1 3.4 2 2 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAK67759.1 - 0.0063 16.6 0.5 0.053 13.6 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Trm112p PF03966.11 GAK67760.1 - 3.2e-19 69.0 0.5 5.7e-19 68.2 0.4 1.4 1 1 0 1 1 1 1 Trm112p-like protein GPI-anchored PF10342.4 GAK67761.1 - 5e-09 36.5 0.3 7.9e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNase_H PF00075.19 GAK67762.1 - 1.5e-27 96.5 0.0 2.3e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 GAK67762.1 - 2.7e-14 52.9 0.0 5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF2370 PF10176.4 GAK67762.1 - 0.0085 15.4 4.2 0.0085 15.4 2.9 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2370) RVT_3 PF13456.1 GAK67762.1 - 0.1 12.4 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like Aminotran_3 PF00202.16 GAK67762.1 - 0.14 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III F5_F8_type_C PF00754.20 GAK67763.1 - 1.3e-05 25.0 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain DUF1765 PF08578.5 GAK67765.1 - 1.1e-30 106.3 1.6 1.8e-30 105.5 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SQS_PSY PF00494.14 GAK67766.1 - 1.1e-77 260.9 5.4 1.8e-77 260.2 3.7 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase FAD_binding_1 PF00667.15 GAK67767.1 - 1.2e-56 191.6 0.0 1.8e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAK67767.1 - 8.8e-34 116.5 0.3 2.4e-33 115.1 0.2 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAK67767.1 - 5.8e-22 78.3 0.0 2.8e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF455 PF04305.9 GAK67767.1 - 0.011 15.0 0.0 0.06 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Flavodoxin_5 PF12724.2 GAK67767.1 - 0.04 13.9 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Abhydrolase_3 PF07859.8 GAK67768.1 - 2.5e-33 115.4 0.1 7.6e-24 84.4 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold LAT PF15234.1 GAK67768.1 - 0.0057 16.1 6.3 0.015 14.7 4.4 1.7 1 0 0 1 1 1 1 Linker for activation of T-cells DUF2424 PF10340.4 GAK67768.1 - 0.037 12.6 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) MSP1_C PF07462.6 GAK67768.1 - 2.7 6.2 4.0 1.2 7.4 0.9 1.8 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ArfGap PF01412.13 GAK67769.1 - 2.5e-41 140.1 2.2 4.8e-41 139.2 1.5 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Med11 PF10280.4 GAK67769.1 - 4.6e-06 26.6 0.1 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Mediator complex protein SPC22 PF04573.7 GAK67770.1 - 1.5e-40 138.2 0.5 1.7e-40 138.0 0.4 1.0 1 0 0 1 1 1 1 Signal peptidase subunit AT_hook PF02178.14 GAK67771.1 - 0.0025 17.2 59.2 1 9.2 1.5 6.6 5 0 0 5 5 5 5 AT hook motif PAS_3 PF08447.6 GAK67772.1 - 0.00015 21.7 2.0 0.0089 16.1 0.0 2.6 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 GAK67772.1 - 0.00026 20.8 8.7 0.00041 20.1 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 GAK67772.1 - 0.006 16.3 0.3 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 GAK67772.1 - 0.11 12.5 1.5 0.66 9.9 0.0 2.5 2 1 1 3 3 3 0 PAS domain BAF1_ABF1 PF04684.8 GAK67772.1 - 0.32 9.7 11.3 0.64 8.8 7.8 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3703 PF12487.3 GAK67774.1 - 5.5 6.6 6.9 14 5.4 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) LAG1-DNAbind PF09271.6 GAK67775.1 - 2.3e-38 131.8 3.1 4.2e-38 130.9 0.0 2.4 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 GAK67775.1 - 2.1e-19 69.8 0.0 1.3e-17 64.0 0.0 3.0 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain FSH1 PF03959.8 GAK67776.1 - 2e-56 190.8 0.0 2e-56 190.8 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Homeobox PF00046.24 GAK67776.1 - 9.1e-17 60.4 3.2 2e-16 59.3 2.2 1.6 1 0 0 1 1 1 1 Homeobox domain Cyt-b5 PF00173.23 GAK67776.1 - 1.8e-09 37.2 0.2 3.8e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ctr PF04145.10 GAK67776.1 - 1.1 9.2 5.9 20 5.2 0.0 2.9 2 0 0 2 2 2 0 Ctr copper transporter family CASP_C PF08172.7 GAK67777.1 - 5e-69 232.0 2.4 5e-69 232.0 1.7 4.6 2 1 1 3 3 3 1 CASP C terminal DUF904 PF06005.7 GAK67777.1 - 0.041 14.1 0.1 0.041 14.1 0.1 7.4 6 3 0 6 6 6 0 Protein of unknown function (DUF904) WD40_alt PF14077.1 GAK67777.1 - 0.41 10.3 4.2 0.62 9.7 0.3 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif HTH_1 PF00126.22 GAK67777.1 - 0.68 9.7 12.5 0.033 13.9 1.7 3.8 3 1 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family ADIP PF11559.3 GAK67777.1 - 1.5 8.7 78.9 0.35 10.7 11.8 7.1 3 3 2 6 6 6 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 GAK67777.1 - 2.2 8.0 60.5 0.31 10.7 2.1 6.2 2 2 3 5 5 5 0 TPR/MLP1/MLP2-like protein CPSase_sm_chain PF00988.17 GAK67778.1 - 2e-44 150.2 0.0 3.2e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 GAK67778.1 - 8.2e-39 133.0 0.0 3e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAK67778.1 - 6.5e-06 25.7 0.4 3.7e-05 23.2 0.3 2.0 1 1 0 1 1 1 1 Peptidase C26 Peptidase_M22 PF00814.20 GAK67778.1 - 0.047 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family DUF1749 PF08538.5 GAK67779.1 - 3.9e-62 209.8 0.0 4e-47 160.5 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 GAK67779.1 - 6.4e-09 36.0 1.4 1.1e-08 35.3 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK67779.1 - 7e-08 32.3 0.0 2.5e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAK67779.1 - 0.00091 18.1 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.8 GAK67779.1 - 0.001 18.6 0.1 0.0022 17.5 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase Peptidase_S9 PF00326.16 GAK67779.1 - 0.0012 18.0 0.1 0.47 9.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF900 PF05990.7 GAK67779.1 - 0.004 16.4 0.1 0.0059 15.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.3 GAK67779.1 - 0.05 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2305 PF10230.4 GAK67779.1 - 0.14 11.5 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DASH_Dam1 PF08653.5 GAK67780.1 - 0.021 14.6 0.6 0.5 10.1 0.4 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF972 PF06156.8 GAK67780.1 - 0.045 14.0 19.0 0.21 11.9 0.6 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF972) IncA PF04156.9 GAK67780.1 - 0.47 10.0 24.4 6.7 6.2 0.3 3.6 3 0 0 3 3 3 0 IncA protein Spectrin PF00435.16 GAK67780.1 - 1.4 9.2 21.7 1.8 8.9 0.6 4.0 4 0 0 4 4 4 0 Spectrin repeat TMF_DNA_bd PF12329.3 GAK67780.1 - 3.7 7.4 24.4 0.14 11.9 1.0 4.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 GAK67780.1 - 7.2 5.5 23.8 1.7 7.6 0.8 2.7 2 1 0 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 GAK67780.1 - 10 5.9 26.2 0.9 9.2 1.5 3.7 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein ABA_GPCR PF12430.3 GAK67781.1 - 1.7e-40 138.2 2.8 3e-40 137.4 1.9 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 GAK67781.1 - 2.2e-12 46.8 0.1 6.9e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) WEMBL PF05701.6 GAK67781.1 - 0.46 8.8 0.3 0.79 8.1 0.0 1.4 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DASH_Duo1 PF08651.5 GAK67782.1 - 5.4e-23 80.3 0.2 9.3e-23 79.6 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 APG6 PF04111.7 GAK67782.1 - 0.65 8.9 0.0 0.65 8.9 0.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF572 PF04502.8 GAK67782.1 - 1.9 7.6 10.1 3.6 6.7 7.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 GAK67782.1 - 6.4 5.7 10.7 18 4.1 7.7 1.5 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain CDC45 PF02724.9 GAK67783.1 - 4.2 5.2 8.7 0.35 8.8 0.9 2.2 2 0 0 2 2 2 0 CDC45-like protein TRP PF06011.7 GAK67785.1 - 8.5e-99 331.0 11.4 1.3e-98 330.4 7.9 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAK67785.1 - 7.9e-33 113.4 0.4 1.1e-32 112.9 0.3 1.2 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 GAK67785.1 - 0.0064 16.7 0.1 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 ML domain HemY_N PF07219.8 GAK67785.1 - 4.5 6.8 7.2 8.5 5.9 3.5 2.5 2 0 0 2 2 2 0 HemY protein N-terminus DUF3154 PF11351.3 GAK67785.1 - 5.8 6.6 8.1 46 3.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) DUF21 PF01595.15 GAK67786.1 - 3.7e-37 127.4 0.9 3.7e-37 127.4 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 GAK67786.1 - 5.8e-07 29.1 1.0 0.0097 15.6 0.0 2.8 3 0 0 3 3 3 2 CBS domain Aldo_ket_red PF00248.16 GAK67787.1 - 1.9e-65 220.5 0.0 2.2e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pept_tRNA_hydro PF01195.14 GAK67788.1 - 4e-24 85.1 0.0 5.6e-20 71.6 0.0 2.6 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase Methyltransf_26 PF13659.1 GAK67788.1 - 4.5e-14 52.4 4.7 7.6e-14 51.7 1.7 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK67788.1 - 8.9e-13 48.0 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK67788.1 - 1.5e-08 35.2 0.2 3.9e-08 33.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 GAK67788.1 - 6.9e-07 28.8 0.0 1.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAK67788.1 - 1.7e-06 28.3 0.0 8.3e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 GAK67788.1 - 3.1e-05 23.2 0.0 5.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.13 GAK67788.1 - 0.0022 17.5 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 GAK67788.1 - 0.0064 15.6 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 GAK67788.1 - 0.0086 15.4 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 GAK67788.1 - 0.026 15.0 0.0 0.078 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 GAK67788.1 - 0.034 13.8 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Eco57I PF07669.6 GAK67788.1 - 0.21 11.9 0.0 0.53 10.6 0.0 1.6 1 0 0 1 1 1 0 Eco57I restriction-modification methylase FliT PF05400.8 GAK67788.1 - 1.9 8.9 7.6 0.22 11.9 0.5 2.6 2 0 0 2 2 2 0 Flagellar protein FliT ATG13 PF10033.4 GAK67789.1 - 1.1e-52 178.7 0.0 1.7e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 Pkinase PF00069.20 GAK67791.1 - 2.4e-52 177.6 0.0 7.2e-52 176.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67791.1 - 3.7e-20 72.0 0.0 6.8e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK67791.1 - 0.0053 16.5 0.1 0.0053 16.5 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAK67791.1 - 0.019 14.2 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family FixO PF02433.10 GAK67791.1 - 2.9 7.1 6.7 7.7 5.8 4.6 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Ribosomal_S9 PF00380.14 GAK67794.1 - 2.6e-35 121.3 0.5 5e-35 120.3 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RFX_DNA_binding PF02257.10 GAK67796.1 - 9.4e-25 86.5 0.1 2.6e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 GAK67796.1 - 0.0099 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Poxvirus D5 protein-like NOA36 PF06524.7 GAK67798.1 - 0.13 11.4 5.1 0.28 10.4 3.5 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 GAK67798.1 - 0.4 8.5 14.3 0.62 7.9 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 GAK67798.1 - 1.7 8.2 11.6 6.3 6.3 8.0 1.9 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 GAK67798.1 - 3.6 7.1 12.6 7.1 6.1 8.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin BPL_LplA_LipB PF03099.14 GAK67799.1 - 9.5e-07 28.8 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PPR_2 PF13041.1 GAK67799.1 - 0.1 12.6 0.0 6.4 6.8 0.0 2.9 3 0 0 3 3 3 0 PPR repeat family PPR PF01535.15 GAK67799.1 - 0.11 12.5 0.0 12 6.1 0.0 3.9 5 0 0 5 5 5 0 PPR repeat DEAD PF00270.24 GAK67800.1 - 3.8e-38 130.6 0.0 8.6e-38 129.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK67800.1 - 2.6e-19 68.8 0.0 5.5e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK67800.1 - 0.00042 20.1 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 GAK67800.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Suf PF05843.9 GAK67801.1 - 0.31 10.7 1.6 0.37 10.4 1.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GWT1 PF06423.7 GAK67802.1 - 1.2e-39 135.5 0.1 3.2e-39 134.1 0.0 1.8 1 0 0 1 1 1 1 GWT1 Exo_endo_phos PF03372.18 GAK67803.1 - 4.1e-23 82.5 1.8 3.5e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family IF-2B PF01008.12 GAK67804.1 - 1.8e-67 227.3 0.0 2.5e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family MHYT PF03707.11 GAK67805.1 - 4.3e-10 39.5 20.5 7.8e-05 22.7 4.0 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Med14 PF08638.6 GAK67807.1 - 1.3e-49 168.0 0.0 2.5e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkinase PF00069.20 GAK67808.1 - 7.5e-09 35.1 0.0 1.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 GAK67808.1 - 1.1e-07 31.3 1.7 0.33 11.1 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.12 GAK67808.1 - 0.0069 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Vac14_Fab1_bd PF12755.2 GAK67808.1 - 0.097 13.0 0.0 4.5 7.7 0.0 2.7 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region DnaJ PF00226.26 GAK67809.1 - 6.3e-15 54.6 3.2 7.4e-15 54.4 0.5 2.3 2 0 0 2 2 2 1 DnaJ domain eIF-3c_N PF05470.7 GAK67810.1 - 2.6e-179 597.1 19.3 2.6e-179 597.1 13.4 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 GAK67810.1 - 6.1e-15 55.4 0.0 1.8e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain FeoC PF09012.5 GAK67810.1 - 0.075 12.7 0.0 0.3 10.8 0.0 2.0 1 0 0 1 1 1 0 FeoC like transcriptional regulator OSCP PF00213.13 GAK67811.1 - 1.5e-35 122.6 2.6 1.5e-35 122.6 1.8 1.6 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit GST_N_3 PF13417.1 GAK67812.1 - 2.5e-11 43.6 0.0 4.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAK67812.1 - 4.6e-10 39.5 0.0 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK67812.1 - 9.7e-10 38.3 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAK67812.1 - 2.9e-09 36.7 0.0 5.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAK67812.1 - 6.1e-08 32.4 0.1 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAK67812.1 - 0.004 17.6 0.0 0.0075 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.13 GAK67813.1 - 9e-50 169.1 0.0 1.3e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NUDE_C PF04880.8 GAK67814.1 - 1.3e-11 45.1 16.7 1.3e-11 45.1 11.6 4.5 2 1 1 4 4 1 1 NUDE protein, C-terminal conserved region Filament PF00038.16 GAK67814.1 - 0.0023 17.4 9.4 0.0023 17.4 6.5 2.5 1 1 1 2 2 2 1 Intermediate filament protein DUF3584 PF12128.3 GAK67814.1 - 0.0081 13.5 18.9 0.012 13.0 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) IncA PF04156.9 GAK67814.1 - 0.019 14.5 27.4 0.1 12.1 10.0 3.0 1 1 1 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 GAK67814.1 - 0.03 14.1 26.4 3.8 7.3 10.5 4.1 2 1 1 3 3 3 0 Prefoldin subunit Stn1 PF10451.4 GAK67814.1 - 0.084 11.7 1.6 0.14 10.9 1.1 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 TPR_MLP1_2 PF07926.7 GAK67814.1 - 0.097 12.4 27.4 0.28 10.9 3.8 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 GAK67814.1 - 0.12 12.7 27.1 0.029 14.6 5.6 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) MCPsignal PF00015.16 GAK67814.1 - 0.12 11.9 6.8 0.022 14.3 0.7 2.4 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WEMBL PF05701.6 GAK67814.1 - 0.16 10.4 30.6 0.013 13.9 17.5 1.7 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DMPK_coil PF08826.5 GAK67814.1 - 0.23 11.4 22.2 0.099 12.5 1.2 3.7 3 0 0 3 3 3 0 DMPK coiled coil domain like Mating_N PF12731.2 GAK67814.1 - 0.28 11.0 5.2 0.3 10.9 0.4 2.5 1 1 1 2 2 2 0 Mating-type protein beta 1 Prominin PF05478.6 GAK67814.1 - 0.33 8.4 8.3 0.46 7.9 5.8 1.1 1 0 0 1 1 1 0 Prominin Bacillus_HBL PF05791.6 GAK67814.1 - 0.33 10.3 8.4 0.045 13.1 2.3 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.10 GAK67814.1 - 0.39 10.2 13.1 0.38 10.2 0.2 3.6 2 1 1 3 3 3 0 Septum formation initiator DUF948 PF06103.6 GAK67814.1 - 0.43 10.4 9.4 5.2 6.9 0.6 3.9 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 GAK67814.1 - 0.45 8.9 13.8 0.84 8.0 9.6 1.4 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 GAK67814.1 - 0.66 9.1 12.8 0.13 11.4 0.7 3.1 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Atg14 PF10186.4 GAK67814.1 - 0.88 8.4 19.7 0.77 8.6 7.5 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4315 PF14193.1 GAK67814.1 - 0.92 9.4 16.5 4.2 7.3 0.3 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4315) HTH_Tnp_1 PF01527.15 GAK67814.1 - 0.96 9.4 10.2 0.097 12.6 0.4 3.6 3 1 1 4 4 4 0 Transposase Laminin_II PF06009.7 GAK67814.1 - 1.2 8.8 16.0 0.052 13.2 3.7 2.5 1 1 1 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.7 GAK67814.1 - 2 8.2 7.3 2.5 7.9 1.5 2.6 2 1 2 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 GAK67814.1 - 2.1 8.8 18.5 0.38 11.1 3.0 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MSA-2c PF12238.3 GAK67814.1 - 2.1 7.9 9.2 0.57 9.8 3.1 2.5 2 1 1 3 3 2 0 Merozoite surface antigen 2c NPV_P10 PF05531.7 GAK67814.1 - 2.2 8.6 6.9 4.1 7.7 0.1 3.1 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sas10_Utp3 PF04000.10 GAK67814.1 - 2.5 8.3 6.6 3.7 7.8 0.6 2.9 2 0 0 2 2 2 0 Sas10/Utp3/C1D family EzrA PF06160.7 GAK67814.1 - 4.9 5.2 21.0 1.4 6.9 2.0 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ERM PF00769.14 GAK67814.1 - 5.8 6.3 33.9 0.34 10.4 11.1 2.7 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF3287 PF11690.3 GAK67814.1 - 8.4 6.5 8.9 0.54 10.3 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) WXG100 PF06013.7 GAK67814.1 - 9.4 6.3 13.1 11 6.0 0.7 4.0 4 1 1 5 5 3 0 Proteins of 100 residues with WXG CLASP_N PF12348.3 GAK67815.1 - 1.4e-23 83.4 0.0 1.6e-06 27.6 0.0 5.1 4 1 0 4 4 4 4 CLASP N terminal HEAT PF02985.17 GAK67815.1 - 4.4e-18 63.6 16.8 0.0079 16.1 0.0 10.1 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.1 GAK67815.1 - 2.6e-15 56.4 24.4 0.0061 16.8 0.0 8.4 5 2 2 8 8 8 7 HEAT repeats Adaptin_N PF01602.15 GAK67815.1 - 9.8e-08 30.7 1.9 0.013 13.8 0.0 5.2 5 1 0 5 5 5 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 GAK67815.1 - 4.2e-06 25.3 0.1 0.0043 15.3 0.0 3.0 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 GAK67815.1 - 0.00011 22.5 27.5 0.29 11.6 0.0 8.7 9 0 0 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAK67815.1 - 0.00013 22.2 0.0 14 6.1 0.0 6.0 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 GAK67815.1 - 0.013 15.2 7.8 0.44 10.4 0.1 5.1 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Glycos_transf_2 PF00535.21 GAK67816.1 - 7.1e-26 90.8 0.0 9.5e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAK67816.1 - 2.2e-09 37.4 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyoxalase PF00903.20 GAK67817.1 - 3.4e-23 82.0 0.2 4.6e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAK67817.1 - 2.6e-17 63.3 0.0 3.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAK67817.1 - 3.6e-09 36.5 0.0 6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 GAK67817.1 - 1.6e-05 24.8 0.0 0.0094 15.8 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase-like domain WD40 PF00400.27 GAK67818.1 - 1.6e-31 107.0 6.5 1.7e-08 34.0 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 GAK67818.1 - 2e-24 86.1 0.1 3.9e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAK67818.1 - 8.9e-12 44.7 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.6 GAK67818.1 - 1.7e-07 30.3 0.5 0.0027 16.5 0.1 3.5 2 2 1 3 3 3 3 Nup133 N terminal like Sigma70_ner PF04546.8 GAK67818.1 - 2.2 7.8 3.7 6.1 6.3 1.9 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region RNA_pol_Rpc34 PF05158.7 GAK67819.1 - 2.3e-80 270.2 1.1 6.4e-70 235.9 0.1 2.2 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit TrmB PF01978.14 GAK67819.1 - 0.0013 18.4 0.9 0.0069 16.0 0.1 2.6 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 GAK67819.1 - 0.012 15.4 0.2 0.033 14.0 0.2 1.7 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MarR PF01047.17 GAK67819.1 - 0.022 14.4 0.1 0.059 13.0 0.1 1.7 1 0 0 1 1 1 0 MarR family Penicillinase_R PF03965.11 GAK67819.1 - 0.13 12.4 1.8 1.9 8.6 0.1 2.5 1 1 1 2 2 2 0 Penicillinase repressor Glyco_hydro_45 PF02015.11 GAK67822.1 - 3.5e-80 268.8 14.7 5.5e-80 268.1 10.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SR-25 PF10500.4 GAK67822.1 - 3.1 7.1 7.7 0.36 10.2 2.1 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.14 GAK67823.1 - 2.6e-21 76.0 0.9 1.3e-11 44.1 0.0 3.3 1 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 GAK67823.1 - 4.5e-07 30.1 0.0 4.5e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK67823.1 - 6.1e-05 22.9 0.0 0.00021 21.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK67823.1 - 9.9e-05 21.3 0.1 0.00018 20.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK67823.1 - 0.0003 19.3 0.0 0.00087 17.8 0.0 1.8 1 0 0 1 1 1 1 HI0933-like protein WD40 PF00400.27 GAK67823.1 - 0.0016 18.2 0.2 1.1 9.2 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat GIDA PF01134.17 GAK67823.1 - 0.0018 17.1 0.1 0.0034 16.2 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAK67823.1 - 0.0024 17.5 0.0 0.009 15.6 0.0 2.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAK67823.1 - 0.0085 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAK67823.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 GAK67823.1 - 0.096 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.5 GAK67823.1 - 0.11 11.3 0.0 0.57 8.9 0.0 2.2 2 1 1 3 3 3 0 Squalene epoxidase Thi4 PF01946.12 GAK67823.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family ARGLU PF15346.1 GAK67823.1 - 0.3 10.8 5.7 0.058 13.1 0.7 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF3534 PF12053.3 GAK67824.1 - 0.098 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) Acyl_transf_3 PF01757.17 GAK67825.1 - 4.2e-35 121.1 28.9 4.2e-35 121.1 20.0 3.1 3 0 0 3 3 3 1 Acyltransferase family Glyco_trans_2_3 PF13632.1 GAK67825.1 - 2.5e-27 95.8 3.1 2.5e-27 95.8 2.2 4.2 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK67825.1 - 1.4e-17 64.2 0.0 2.8e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fumarate_red_C PF02300.12 GAK67827.1 - 0.89 9.4 8.4 0.24 11.2 3.4 1.8 2 0 0 2 2 2 0 Fumarate reductase subunit C Cellulase PF00150.13 GAK67828.1 - 0.00024 20.4 0.1 0.57 9.3 0.0 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 GAK67829.1 - 1.9e-45 155.0 0.0 3.3e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67829.1 - 1.4e-28 99.6 0.0 5.5e-27 94.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase CAP_GLY PF01302.20 GAK67830.1 - 2.6e-17 62.2 0.2 4.2e-17 61.5 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain PI3_PI4_kinase PF00454.22 GAK67831.1 - 2.4e-36 125.3 0.0 3.9e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pkinase PF00069.20 GAK67832.1 - 8.4e-33 113.6 0.0 4.3e-26 91.6 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67832.1 - 1.7e-16 60.0 0.0 1.4e-13 50.4 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK67832.1 - 0.00021 20.3 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 GAK67832.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pex16 PF08610.5 GAK67833.1 - 2.2e-74 250.4 0.0 3.7e-46 157.6 0.0 2.8 1 1 1 2 2 2 2 Peroxisomal membrane protein (Pex16) Pkinase PF00069.20 GAK67834.1 - 1.4e-55 188.2 0.0 1.9e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK67834.1 - 1.3e-39 135.9 0.0 2.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK67834.1 - 4.4e-06 25.8 0.0 8.1e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Prominin PF05478.6 GAK67834.1 - 0.13 9.7 0.0 0.19 9.2 0.0 1.1 1 0 0 1 1 1 0 Prominin MmgE_PrpD PF03972.9 GAK67835.1 - 4.5e-149 496.4 0.0 6e-149 496.0 0.0 1.2 1 0 0 1 1 1 1 MmgE/PrpD family PALP PF00291.20 GAK67836.1 - 3.2e-65 220.3 0.1 4e-65 220.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3425 PF11905.3 GAK67837.1 - 1.2e-18 67.3 0.9 2.2e-18 66.4 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAK67837.1 - 1.4 8.8 7.5 2.8 7.9 5.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor PPR_2 PF13041.1 GAK67838.1 - 1.9e-10 40.5 0.0 0.0041 17.0 0.1 5.9 6 1 1 7 7 7 3 PPR repeat family PPR PF01535.15 GAK67838.1 - 1.7e-05 24.4 2.3 16 5.7 0.0 6.5 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.1 GAK67838.1 - 6.1e-05 22.9 4.9 7.6 7.1 0.0 8.1 10 0 0 10 10 10 1 Pentatricopeptide repeat domain KH_1 PF00013.24 GAK67839.1 - 2e-83 273.9 25.2 3e-12 45.9 0.0 14.6 15 1 0 15 15 15 10 KH domain KH_3 PF13014.1 GAK67839.1 - 1.9e-58 193.2 15.8 1.2e-07 31.1 0.7 14.4 14 0 0 14 14 14 8 KH domain KH_2 PF07650.12 GAK67839.1 - 1.4e-15 56.5 21.3 0.0066 15.9 0.6 9.8 9 1 1 10 10 10 5 KH domain KH_4 PF13083.1 GAK67839.1 - 1.1e-06 28.2 21.1 0.11 12.1 0.0 8.2 7 1 2 9 9 9 3 KH domain SLS PF14611.1 GAK67839.1 - 0.0023 17.3 14.7 0.36 10.2 0.3 7.5 8 1 1 9 9 9 1 Mitochondrial inner-membrane-bound regulator Phytoreo_P8 PF07124.6 GAK67839.1 - 0.11 11.0 0.5 0.21 10.2 0.4 1.3 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 CorA PF01544.13 GAK67839.1 - 0.35 9.8 0.0 0.88 8.5 0.0 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4112 PF13430.1 GAK67840.1 - 1.9e-27 95.2 0.6 4.9e-27 93.9 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MFS_1 PF07690.11 GAK67840.1 - 4.4e-20 71.6 43.5 1.1e-13 50.6 16.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Zip PF02535.17 GAK67840.1 - 0.0034 16.4 2.0 0.0034 16.4 1.4 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter OATP PF03137.15 GAK67840.1 - 0.11 10.5 8.6 0.097 10.7 1.6 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BAF1_ABF1 PF04684.8 GAK67840.1 - 2.1 7.0 11.5 3.7 6.2 8.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HUN PF08729.5 GAK67842.1 - 1.6e-12 47.0 1.4 1.6e-12 47.0 1.0 2.6 2 0 0 2 2 2 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 GAK67842.1 - 1.7e-08 34.4 0.8 1.7e-08 34.4 0.6 1.7 2 0 0 2 2 2 1 Ubinuclein conserved middle domain NOA36 PF06524.7 GAK67842.1 - 6.9 5.8 13.9 14 4.8 9.6 1.5 1 0 0 1 1 1 0 NOA36 protein DUF815 PF05673.8 GAK67843.1 - 0.012 14.6 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 GAK67843.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain NMD3 PF04981.8 GAK67844.1 - 1.7e-80 269.5 2.9 2.9e-80 268.7 2.0 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 GAK67844.1 - 0.0059 16.4 5.8 0.13 12.1 3.4 2.7 2 1 1 3 3 3 2 Double zinc ribbon zf-C3HC4_3 PF13920.1 GAK67844.1 - 2 8.1 5.9 0.32 10.7 0.4 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF2340 PF10209.4 GAK67845.1 - 3.3e-47 159.6 0.5 4.1e-47 159.3 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Whi5 PF08528.6 GAK67848.1 - 2.8e-11 42.7 0.0 4.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Whi5 like TRAPP PF04051.11 GAK67849.1 - 1.5e-36 125.1 0.0 2.3e-36 124.6 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Haemagg_act PF05860.8 GAK67849.1 - 0.061 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 haemagglutination activity domain dsDNA_bind PF01984.15 GAK67850.1 - 4e-29 100.7 3.1 6.1e-29 100.1 2.1 1.3 1 1 0 1 1 1 1 Double-stranded DNA-binding domain CT47 PF15623.1 GAK67850.1 - 0.12 12.0 1.5 0.15 11.7 1.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Steroid_dh PF02544.11 GAK67851.1 - 1.1e-25 90.1 6.2 3e-19 69.2 4.4 4.4 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 GAK67851.1 - 0.00027 20.3 0.3 0.00047 19.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) FKBP_C PF00254.23 GAK67852.1 - 1.5e-27 95.4 0.0 2.7e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase JmjC PF02373.17 GAK67852.1 - 7.6e-15 55.1 0.0 2.4e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 GAK67852.1 - 9.8e-05 21.9 0.0 0.092 12.2 0.0 2.4 2 0 0 2 2 2 2 Cupin-like domain zf-B_box PF00643.19 GAK67852.1 - 0.26 11.2 7.8 0.7 9.8 5.4 1.7 1 0 0 1 1 1 0 B-box zinc finger FYVE PF01363.16 GAK67852.1 - 2.9 7.8 15.3 2.1 8.3 7.4 2.5 2 0 0 2 2 2 0 FYVE zinc finger Inhibitor_Mig-6 PF11555.3 GAK67854.1 - 0.026 14.8 2.9 0.081 13.3 2.0 1.8 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 SPDY PF03771.11 GAK67854.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF317) Maf1 PF09174.5 GAK67855.1 - 1.8e-33 115.9 0.0 4.3e-27 95.1 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator TruD PF01142.13 GAK67856.1 - 7.2e-57 192.7 0.0 1e-53 182.4 0.0 4.5 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) OPT PF03169.10 GAK67857.1 - 4.4e-156 520.9 48.1 5.1e-156 520.7 33.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FA_hydroxylase PF04116.8 GAK67858.1 - 9.6e-16 58.1 11.7 9.6e-16 58.1 8.1 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_3 PF00933.16 GAK67859.1 - 3.9e-79 265.7 0.0 6.3e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAK67859.1 - 4.1e-50 170.4 0.9 8.4e-50 169.3 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAK67859.1 - 1.7e-18 66.2 0.0 4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PGAP1 PF07819.8 GAK67860.1 - 7.7e-56 189.1 0.0 1.1e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAK67860.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MutS_III PF05192.13 GAK67862.1 - 0.0056 16.4 0.0 0.016 15.0 0.0 1.9 2 1 0 2 2 2 1 MutS domain III His_Phos_2 PF00328.17 GAK67867.1 - 2.7e-74 250.5 0.0 3.8e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 GAK67867.1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TspO_MBR PF03073.10 GAK67868.1 - 1.4e-47 160.9 7.8 1.6e-47 160.7 5.4 1.0 1 0 0 1 1 1 1 TspO/MBR family AMMECR1 PF01871.12 GAK67869.1 - 4.2e-39 133.4 0.0 9.4e-29 99.7 0.0 2.1 2 0 0 2 2 2 2 AMMECR1 AhpC-TSA PF00578.16 GAK67870.1 - 5.6e-32 110.0 0.0 9.1e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAK67870.1 - 2.1e-10 40.2 0.0 3.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 GAK67870.1 - 1.2e-09 37.6 0.0 2.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 GAK67870.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ras PF00071.17 GAK67872.1 - 3.6e-43 146.7 0.2 6.7e-41 139.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAK67872.1 - 7.7e-20 71.5 0.1 1.5e-19 70.6 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK67872.1 - 2.4e-11 43.1 0.1 4.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAK67872.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAK67872.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAK67872.1 - 0.0017 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 GAK67872.1 - 0.095 11.8 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 GAK67872.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 GAK67873.1 - 1.1e-133 445.1 0.0 3.6e-133 443.4 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 GAK67873.1 - 7.5e-27 94.2 0.0 2.5e-26 92.5 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 GAK67873.1 - 3e-08 33.4 0.0 2.8e-06 27.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAK67873.1 - 2.4e-07 30.1 0.0 1.7e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAK67873.1 - 0.012 15.1 0.1 0.059 12.9 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAK67873.1 - 0.11 11.9 0.1 0.95 8.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Borrelia_lipo_2 PF06238.6 GAK67873.1 - 0.2 11.7 0.2 0.5 10.4 0.1 1.6 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein SLAC1 PF03595.12 GAK67874.1 - 9.5e-81 270.9 46.0 1.1e-80 270.7 31.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel U79_P34 PF03064.11 GAK67874.1 - 0.62 9.5 5.1 0.92 8.9 3.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Acyl-CoA_dh_1 PF00441.19 GAK67875.1 - 1.4e-26 93.4 4.5 2e-26 92.8 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAK67875.1 - 8.8e-15 53.9 0.1 3.2e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAK67875.1 - 3.8e-11 43.3 4.8 6.8e-11 42.5 3.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAK67875.1 - 9.3e-10 39.0 0.0 2.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain WLM PF08325.5 GAK67876.1 - 3.3e-25 89.0 0.0 6.2e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 GAK67876.1 - 0.0053 16.1 0.1 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin family DUF45 PF01863.12 GAK67876.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 Paralemmin PF03285.10 GAK67876.1 - 0.034 13.6 1.3 3.5 7.0 0.3 2.2 2 0 0 2 2 2 0 Paralemmin C2 PF00168.25 GAK67877.1 - 6.3e-11 41.9 0.0 1.5e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 C2 domain cwf21 PF08312.7 GAK67878.1 - 1.8e-14 53.2 11.3 1.8e-14 53.2 7.8 2.8 3 1 0 3 3 3 1 cwf21 domain MIP-T3 PF10243.4 GAK67878.1 - 0.013 13.9 51.2 0.017 13.6 35.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ribonuclease_3 PF00636.21 GAK67879.1 - 6.2e-29 100.7 0.0 5.4e-16 59.0 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAK67879.1 - 3e-18 66.0 0.5 2.1e-09 37.4 0.0 3.6 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 GAK67879.1 - 3.9e-16 58.6 0.0 1.1e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 GAK67879.1 - 2e-11 43.6 0.1 4.6e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK67879.1 - 2e-09 37.1 0.0 4.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAK67879.1 - 8.1e-06 25.7 0.0 2.5e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 GAK67879.1 - 0.00094 19.7 0.1 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif AAA_26 PF13500.1 GAK67879.1 - 0.088 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.6 GAK67880.1 - 5.3 5.0 9.2 10 4.0 6.4 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Not3 PF04065.10 GAK67881.1 - 4.6e-96 320.5 23.3 7e-96 320.0 16.2 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 GAK67881.1 - 1.8e-45 154.1 10.4 5.4e-45 152.5 7.2 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 GAK67881.1 - 0.0028 17.1 2.7 0.0083 15.6 1.9 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 GAK67881.1 - 0.084 12.8 6.7 0.057 13.3 1.1 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 COX15-CtaA PF02628.10 GAK67882.1 - 4.7e-78 262.1 18.0 9.8e-78 261.0 12.5 1.5 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosomal_L19 PF01245.15 GAK67882.1 - 2.4e-26 91.7 0.3 3.8e-26 91.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 MFS_1 PF07690.11 GAK67883.1 - 4.7e-29 101.1 35.2 3.1e-26 91.9 10.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK67883.1 - 8.8e-16 57.5 2.2 8.8e-16 57.5 1.6 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter SIP1 PF04938.7 GAK67884.1 - 2.4e-15 56.5 0.0 4.2e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TFIID-31kDa PF02291.10 GAK67885.1 - 2.7e-35 120.9 0.3 1.5e-24 86.1 0.0 2.6 3 0 0 3 3 3 2 Transcription initiation factor IID, 31kD subunit Ribosomal_S14 PF00253.16 GAK67885.1 - 9.2e-20 69.7 0.3 2e-19 68.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Bromo_TP PF07524.8 GAK67885.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated zf-CCHC PF00098.18 GAK67886.1 - 5e-10 38.8 12.0 1.4e-05 24.7 1.2 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 GAK67886.1 - 1.1e-07 31.4 0.6 1.9e-07 30.6 0.4 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 GAK67886.1 - 1.6e-06 27.6 10.6 0.00042 19.9 2.1 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 GAK67886.1 - 0.00021 20.8 0.1 0.00048 19.7 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 GAK67886.1 - 2 8.1 10.6 4.3 7.0 2.0 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 GAK67886.1 - 5.5 6.7 13.3 1.3 8.7 1.5 2.7 1 1 1 2 2 2 0 Zinc knuckle ABC_tran PF00005.22 GAK67887.1 - 3.6e-47 160.0 0.0 5.2e-26 91.5 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAK67887.1 - 3.6e-16 59.9 0.1 0.01 15.8 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 GAK67887.1 - 8.1e-12 44.8 0.2 0.00037 19.8 0.0 3.4 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 GAK67887.1 - 3.4e-08 33.0 0.6 6.8e-08 32.0 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 GAK67887.1 - 1.9e-06 27.2 0.5 0.053 13.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAK67887.1 - 5.7e-06 26.2 0.0 0.014 15.3 0.0 3.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_15 PF13175.1 GAK67887.1 - 6.6e-06 25.4 0.1 0.22 10.5 0.1 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 GAK67887.1 - 1.9e-05 25.1 4.0 0.077 13.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 GAK67887.1 - 3e-05 24.4 1.8 0.018 15.5 0.0 3.6 3 1 0 3 3 2 1 Miro-like protein AAA_28 PF13521.1 GAK67887.1 - 7.9e-05 22.6 0.0 0.2 11.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 GAK67887.1 - 0.00043 19.8 2.0 1.7 7.9 0.1 4.3 4 1 0 4 4 4 1 AAA-like domain DUF87 PF01935.12 GAK67887.1 - 0.00062 19.6 0.1 0.21 11.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 GAK67887.1 - 0.00095 18.3 0.1 0.03 13.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 GAK67887.1 - 0.001 17.8 0.7 0.16 10.7 0.1 2.7 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 GAK67887.1 - 0.0012 19.0 0.1 4.5 7.4 0.0 4.0 5 0 0 5 5 4 0 AAA domain SbcCD_C PF13558.1 GAK67887.1 - 0.0017 18.2 0.0 0.28 11.1 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Tudor-knot PF11717.3 GAK67887.1 - 0.0018 17.9 0.7 0.0042 16.7 0.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_17 PF13207.1 GAK67887.1 - 0.0018 19.0 0.2 1.3 9.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 GAK67887.1 - 0.0019 18.1 0.0 0.85 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain CLASP_N PF12348.3 GAK67887.1 - 0.0043 16.4 0.1 11 5.3 0.0 3.6 3 0 0 3 3 3 0 CLASP N terminal AAA_25 PF13481.1 GAK67887.1 - 0.011 15.1 0.8 2.6 7.4 0.0 3.6 4 0 0 4 4 3 0 AAA domain MobB PF03205.9 GAK67887.1 - 0.011 15.3 0.1 2 8.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arm PF00514.18 GAK67887.1 - 0.023 14.5 0.6 0.14 12.0 0.2 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat NACHT PF05729.7 GAK67887.1 - 0.033 13.8 0.2 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 GAK67887.1 - 0.036 13.7 0.1 7.6 6.1 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase Dynamin_N PF00350.18 GAK67887.1 - 0.037 13.8 0.0 0.39 10.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 GAK67887.1 - 0.056 13.7 0.4 8.2 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain GTP_EFTU PF00009.22 GAK67887.1 - 0.077 12.4 0.2 3.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 GAK67887.1 - 0.094 12.1 0.1 12 5.3 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 GAK67887.1 - 0.12 12.5 0.0 6.4 7.0 0.0 3.4 3 0 0 3 3 3 0 RNA helicase DUF3720 PF12517.3 GAK67887.1 - 0.27 11.9 7.8 0.094 13.4 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) HEAT_EZ PF13513.1 GAK67887.1 - 0.35 11.4 13.0 5.3 7.6 0.0 5.6 4 2 2 6 6 6 0 HEAT-like repeat AAA_16 PF13191.1 GAK67887.1 - 1.7 8.6 8.2 2.4 8.0 0.1 3.9 4 1 0 4 4 3 0 AAA ATPase domain TRAPPC9-Trs120 PF08626.6 GAK67889.1 - 3.9e-77 259.7 0.0 8.6e-62 208.8 0.0 2.7 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GATA PF00320.22 GAK67889.1 - 8.7e-18 63.3 1.8 1.7e-17 62.4 1.2 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 GAK67889.1 - 1.1e-13 50.5 2.6 2.1e-13 49.6 1.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF155 PF02582.9 GAK67890.1 - 2.5e-55 187.0 0.0 4.4e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ank_2 PF12796.2 GAK67891.1 - 1e-37 128.3 3.3 6.2e-10 39.2 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAK67891.1 - 1.1e-28 97.5 6.6 2.5e-07 30.1 0.2 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 GAK67891.1 - 4.8e-24 84.2 10.7 6.7e-08 32.8 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAK67891.1 - 5.2e-24 83.7 6.0 5e-09 36.1 0.0 5.4 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAK67891.1 - 2.9e-19 67.2 1.4 0.0001 22.2 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat zf-DHHC PF01529.15 GAK67891.1 - 3.9e-13 49.1 0.1 4.1e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 DHHC palmitoyltransferase Adaptin_N PF01602.15 GAK67892.1 - 1.8e-136 455.5 11.0 2.2e-136 455.2 7.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 GAK67892.1 - 6.7e-26 91.2 5.7 1.8e-24 86.5 0.9 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAK67892.1 - 2.7e-15 56.4 13.7 1e-09 38.5 0.4 5.2 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 GAK67892.1 - 8.1e-10 37.9 1.3 0.016 15.2 0.0 4.9 4 0 0 4 4 4 3 HEAT repeat CLASP_N PF12348.3 GAK67892.1 - 0.00013 21.3 0.2 2.5 7.4 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal Cnd3 PF12719.2 GAK67892.1 - 0.00042 19.4 0.4 0.11 11.5 0.0 2.5 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 GAK67892.1 - 0.00081 19.1 2.3 0.59 10.0 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAK67892.1 - 0.0023 18.3 6.5 0.66 10.5 0.1 5.8 5 1 1 6 6 6 1 HEAT-like repeat Collagen PF01391.13 GAK67893.1 - 2.7 7.6 13.5 2.1e+02 1.5 9.4 2.5 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) COesterase PF00135.23 GAK67894.1 - 1.7e-96 324.1 0.0 2.2e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAK67894.1 - 3.5e-12 46.3 0.2 6e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAK67894.1 - 0.00014 21.1 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAK67894.1 - 0.0025 17.5 2.6 0.022 14.5 0.3 2.8 2 1 1 3 3 3 2 Alpha/beta hydrolase family MIF4G PF02854.14 GAK67896.1 - 0.00058 19.3 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain Ribosomal_S21 PF01165.15 GAK67897.1 - 7.7e-13 47.6 6.3 1.2e-12 47.0 4.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Pheromone PF08015.6 GAK67897.1 - 0.9 10.4 5.8 0.35 11.7 2.1 1.8 2 1 0 2 2 2 0 Fungal mating-type pheromone Fungal_trans PF04082.13 GAK67899.1 - 5.4e-26 91.0 0.0 7.8e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK67899.1 - 1.5e-09 37.6 1.5 2.9e-09 36.6 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Solute_trans_a PF03619.11 GAK67901.1 - 1e-97 326.7 10.5 1.3e-97 326.4 7.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha eIF-1a PF01176.14 GAK67902.1 - 1.1e-27 95.2 0.1 1.6e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NOA36 PF06524.7 GAK67902.1 - 1.9 7.6 4.6 2.2 7.4 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein Sugar_tr PF00083.19 GAK67903.1 - 4.4e-107 358.4 22.1 5.6e-107 358.1 15.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK67903.1 - 8.6e-24 83.8 26.4 8.6e-24 83.8 18.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAK67903.1 - 1.7e-06 26.7 26.2 8.3e-05 21.1 1.6 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 GAK67903.1 - 6.8e-06 24.5 0.5 1.5e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 GAK67903.1 - 0.00013 20.8 2.2 0.00027 19.7 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) zf-CCCH PF00642.19 GAK67904.1 - 1.2e-12 47.1 14.3 1.1e-06 28.1 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 GAK67904.1 - 0.00018 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phos_pyr_kin PF08543.7 GAK67904.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DEAD PF00270.24 GAK67905.1 - 6.6e-38 129.8 0.0 1.1e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK67905.1 - 3e-23 81.4 0.0 3.3e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAK67905.1 - 0.00086 19.1 0.0 0.0048 16.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rxt3 PF08642.5 GAK67906.1 - 1.2e-19 70.5 0.9 3.1e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 MIP-T3 PF10243.4 GAK67906.1 - 4.6e-08 31.9 15.9 4.6e-08 31.9 11.0 2.7 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 LCCL PF03815.14 GAK67906.1 - 0.023 14.6 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 LCCL domain CAF-1_p150 PF11600.3 GAK67906.1 - 0.081 12.3 65.0 0.58 9.4 35.8 3.6 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAPS PF04499.10 GAK67906.1 - 0.094 11.3 2.3 0.14 10.7 1.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ESCRT-II PF05871.7 GAK67907.1 - 1.3e-47 161.2 0.0 1.8e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit UPRTase PF14681.1 GAK67908.1 - 4.9e-79 264.3 0.0 5.6e-79 264.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAK67908.1 - 4.3e-05 23.2 0.0 7.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PSCyt3 PF07627.6 GAK67909.1 - 0.017 14.9 1.6 0.11 12.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) zf-C2H2_2 PF12756.2 GAK67909.1 - 0.022 14.8 0.6 4.9 7.3 0.1 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.1 GAK67909.1 - 0.52 10.0 3.0 4 7.2 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 GAK67909.1 - 1.2 8.8 3.9 4.2 7.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain LSM PF01423.17 GAK67910.1 - 2.7e-16 58.8 0.0 3.7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.11 GAK67911.1 - 1.4e-27 96.3 27.0 1.4e-27 96.3 18.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK67911.1 - 5.2e-14 51.6 1.9 5.2e-14 51.6 1.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Abhydrolase_6 PF12697.2 GAK67913.1 - 7.6e-19 68.5 0.1 1.1e-18 68.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK67913.1 - 1.2e-17 63.9 0.0 6.8e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAK67913.1 - 2.7e-09 35.9 0.2 3.5e-08 32.3 0.0 2.3 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 GAK67913.1 - 3.4e-09 36.5 0.0 4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 GAK67913.1 - 1.6e-08 34.0 0.0 3.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 GAK67913.1 - 1.1e-07 31.3 0.0 1.5e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAK67913.1 - 3.9e-06 26.7 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.8 GAK67913.1 - 4.9e-05 21.7 0.3 0.17 10.1 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.15 GAK67913.1 - 0.00052 19.6 0.0 0.003 17.1 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAK67913.1 - 0.0011 18.5 0.0 0.0047 16.5 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.6 GAK67913.1 - 0.0093 14.5 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) PTCB-BRCT PF12738.2 GAK67914.1 - 1.2e-18 66.6 3.6 1.4e-14 53.7 0.1 5.2 6 0 0 6 6 6 2 twin BRCT domain BRCT PF00533.21 GAK67914.1 - 1.9e-16 59.9 0.0 7.5e-08 32.4 0.0 6.6 6 1 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.17 GAK67915.1 - 4.4e-13 48.6 0.0 6.7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK67915.1 - 7.9e-11 41.7 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK67915.1 - 4.9e-07 29.5 0.0 8.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 GAK67915.1 - 1.7e-05 25.1 9.3 1.7e-05 25.1 6.5 2.7 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 DUF221 PF02714.10 GAK67916.1 - 8e-86 287.8 23.3 1.3e-85 287.1 16.2 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAK67916.1 - 3.1e-38 130.8 0.3 1.1e-37 129.0 0.2 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAK67916.1 - 3.9e-18 65.7 0.0 8.5e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Beach PF02138.13 GAK67917.1 - 1.5e-103 345.9 0.0 4.8e-103 344.3 0.0 1.8 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.27 GAK67917.1 - 4.2e-11 42.2 8.3 1.7e-05 24.4 0.5 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat PH_BEACH PF14844.1 GAK67917.1 - 3.1e-09 36.6 0.0 7.4e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FYVE PF01363.16 GAK67917.1 - 2.6e-07 30.4 9.2 4.9e-07 29.5 6.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 GAK67917.1 - 6.5 6.7 9.5 25 4.8 6.6 1.9 1 1 0 1 1 1 0 IBR domain HSP20 PF00011.16 GAK67918.1 - 8e-17 60.9 0.3 1.4e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF1556 PF07590.6 GAK67918.1 - 0.042 14.0 1.2 0.092 12.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) GvpH PF05455.6 GAK67918.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 GvpH PI-PLC-X PF00388.14 GAK67919.1 - 0.0048 16.3 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PH PF00169.24 GAK67920.1 - 1.5e-06 28.3 0.0 3.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAK67920.1 - 0.029 14.5 0.2 0.068 13.4 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Helicase_C_3 PF13625.1 GAK67921.1 - 9e-28 96.6 0.0 2.3e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK67921.1 - 6.8e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAK67921.1 - 7e-13 48.0 0.1 1.2e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAK67921.1 - 7.2e-10 38.5 0.1 1.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK67921.1 - 1e-07 31.5 0.8 2.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ras PF00071.17 GAK67922.1 - 9.7e-49 164.8 0.0 1.1e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK67922.1 - 8.8e-16 58.4 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAK67922.1 - 5.3e-08 32.2 0.0 7.1e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CPT PF07931.7 GAK67922.1 - 0.0015 18.2 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Gtr1_RagA PF04670.7 GAK67922.1 - 0.0018 17.4 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAK67922.1 - 0.003 17.0 0.0 0.019 14.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAK67922.1 - 0.0068 15.6 0.0 0.0089 15.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 GAK67922.1 - 0.098 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 GAK67922.1 - 0.15 11.5 0.0 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UQ_con PF00179.21 GAK67923.1 - 2.4e-24 85.3 0.0 3.2e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Abhydrolase_3 PF07859.8 GAK67924.1 - 9.6e-24 84.1 0.0 2.1e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAK67924.1 - 4.6e-06 26.4 0.0 7.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 GAK67924.1 - 4.2e-05 22.3 0.0 6.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF1168 PF06658.7 GAK67925.1 - 1.8e-37 127.9 15.4 2.7e-37 127.4 10.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Vps16_C PF04840.7 GAK67926.1 - 2.5e-70 236.9 4.6 8.7e-47 159.6 2.1 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.8 GAK67926.1 - 1.3e-69 234.7 0.0 2.1e-43 148.3 0.0 3.3 3 0 0 3 3 3 3 Vps16, N-terminal region WLM PF08325.5 GAK67927.1 - 1e-46 159.1 3.8 1e-46 159.1 2.7 2.8 2 2 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 GAK67927.1 - 6.1e-06 25.2 3.5 1.1e-05 24.4 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 GAK67927.1 - 0.0057 16.4 0.2 0.019 14.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function DUF45 DUF2509 PF10713.4 GAK67927.1 - 0.12 12.1 1.8 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2509) GATA PF00320.22 GAK67929.1 - 4.9e-12 44.9 2.4 9.3e-12 44.0 1.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Sugar_tr PF00083.19 GAK67930.1 - 1.8e-85 287.2 20.4 2.3e-85 286.8 14.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK67930.1 - 7.2e-20 70.9 20.1 7.2e-20 70.9 13.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily GST_N PF02798.15 GAK67931.1 - 2.3e-13 50.1 0.0 4.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAK67931.1 - 7.4e-12 45.3 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAK67931.1 - 1.5e-11 44.1 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3028 PF11229.3 GAK67931.1 - 0.16 10.2 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) Ribosomal_L5_C PF00673.16 GAK67932.1 - 3.1e-22 78.1 0.0 5.1e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 GAK67932.1 - 2.7e-17 62.3 0.1 5.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 PI3_PI4_kinase PF00454.22 GAK67934.1 - 3.9e-46 157.4 0.0 6.9e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 GAK67934.1 - 9.1e-28 96.9 0.1 2.4e-27 95.6 0.0 1.8 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 GAK67934.1 - 1e-08 34.4 0.1 2.9e-08 33.0 0.1 1.8 1 0 0 1 1 1 1 FATC domain PDH PF02153.12 GAK67935.1 - 4.7e-15 55.1 0.0 1.2e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 GAK67935.1 - 1.1e-05 25.3 0.0 2.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAK67935.1 - 1.8e-05 25.0 0.1 0.0006 20.2 0.0 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 GAK67935.1 - 0.0039 17.2 0.1 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 GAK67935.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 GAK67935.1 - 0.012 15.1 0.0 0.026 13.9 0.0 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 GAK67935.1 - 0.012 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAK67935.1 - 0.11 12.0 0.4 0.48 10.0 0.0 2.2 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Remorin_C PF03763.8 GAK67935.1 - 0.12 11.8 2.2 0.24 10.9 1.5 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region DUF1777 PF08648.7 GAK67936.1 - 9.7e-24 84.0 47.4 6.5e-23 81.3 32.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) NDUF_B4 PF07225.7 GAK67937.1 - 7.9e-05 22.4 0.1 8.7e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Retro_M PF02813.9 GAK67937.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral M domain PX PF00787.19 GAK67938.1 - 2.3e-08 33.8 0.0 5.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Melibiase PF02065.13 GAK67939.1 - 7.3e-35 120.4 0.0 3.1e-19 68.9 0.0 2.1 2 0 0 2 2 2 2 Melibiase Raffinose_syn PF05691.7 GAK67939.1 - 0.00014 19.5 0.0 0.00024 18.8 0.0 1.3 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 CFEM PF05730.6 GAK67940.1 - 0.00036 20.2 10.0 0.00068 19.4 6.9 1.4 1 0 0 1 1 1 1 CFEM domain SNF2_N PF00176.18 GAK67942.1 - 1.3e-10 40.6 0.0 2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAK67942.1 - 0.036 13.8 0.2 0.2 11.4 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Nucleo_P87 PF07267.6 GAK67942.1 - 0.27 9.8 1.8 0.38 9.3 1.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HMA PF00403.21 GAK67943.1 - 4.3e-12 45.9 0.4 1.3e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 Heavy-metal-associated domain YtkA PF13115.1 GAK67943.1 - 0.031 14.6 0.5 0.053 13.8 0.1 1.6 2 0 0 2 2 2 0 YtkA-like HA2 PF04408.18 GAK67944.1 - 2.7e-25 88.3 0.0 1.2e-24 86.2 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAK67944.1 - 5.4e-22 77.7 0.0 3e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAK67944.1 - 3.6e-13 49.1 0.0 9.9e-13 47.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK67944.1 - 1.8e-08 34.0 0.0 4.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAK67944.1 - 1.6e-06 28.3 0.1 4.4e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAK67944.1 - 0.0011 17.9 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 GAK67944.1 - 0.0037 17.1 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_14 PF13173.1 GAK67944.1 - 0.011 15.6 0.1 0.074 12.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAK67944.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 GAK67944.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase SRP54 PF00448.17 GAK67944.1 - 0.017 14.5 0.1 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 GAK67944.1 - 0.024 14.9 0.4 0.064 13.5 0.0 2.0 2 0 0 2 2 1 0 ABC transporter Sigma54_activ_2 PF14532.1 GAK67944.1 - 0.024 14.6 0.1 0.22 11.5 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain KaiC PF06745.8 GAK67944.1 - 0.031 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 GAK67944.1 - 0.048 13.3 0.1 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Myosin_head PF00063.16 GAK67944.1 - 0.11 10.5 0.0 0.18 9.7 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) AAA_23 PF13476.1 GAK67944.1 - 0.12 12.7 0.1 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 GAK67944.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Miro PF08477.8 GAK67944.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SE PF08491.5 GAK67944.1 - 0.29 9.9 0.0 0.5 9.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase AAA_18 PF13238.1 GAK67944.1 - 1.3 9.3 3.6 0.86 9.9 0.0 2.6 2 1 0 2 2 1 0 AAA domain p450 PF00067.17 GAK67945.1 - 9.8e-60 202.3 0.0 2.5e-52 177.9 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Perilipin PF03036.11 GAK67946.1 - 1.3e-10 40.7 0.5 1.8e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Perilipin family LIF_OSM PF01291.12 GAK67946.1 - 0.083 12.8 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 LIF / OSM family AAA PF00004.24 GAK67947.1 - 4.8e-57 191.8 0.0 1.9e-43 147.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 GAK67947.1 - 6.3e-25 87.0 0.1 1.4e-24 85.8 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_25 PF13481.1 GAK67947.1 - 4e-10 39.4 4.2 0.0064 15.9 0.0 4.3 2 2 2 4 4 4 3 AAA domain AAA_16 PF13191.1 GAK67947.1 - 4.3e-10 39.8 11.3 6.1e-05 23.0 0.1 5.2 3 2 2 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 GAK67947.1 - 8.7e-10 39.4 0.0 0.0016 19.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAK67947.1 - 5.4e-08 33.0 0.9 0.012 15.7 0.1 4.2 3 2 0 3 3 2 2 AAA domain AAA_19 PF13245.1 GAK67947.1 - 8.6e-07 28.6 1.3 0.0024 17.5 0.2 3.2 2 1 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 GAK67947.1 - 1.3e-06 28.3 0.0 0.06 13.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAK67947.1 - 1.6e-06 28.0 0.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 GAK67947.1 - 3e-06 26.4 0.0 0.003 16.6 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 GAK67947.1 - 4.1e-06 27.1 0.0 0.038 14.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 GAK67947.1 - 5.2e-06 25.6 0.3 0.024 13.7 0.1 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_28 PF13521.1 GAK67947.1 - 9.4e-06 25.6 0.1 0.027 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 GAK67947.1 - 9.5e-06 24.8 0.0 0.0049 15.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 GAK67947.1 - 1.4e-05 24.3 0.5 0.1 11.7 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAK67947.1 - 2.3e-05 24.1 0.3 0.39 10.4 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAK67947.1 - 6e-05 23.1 0.0 0.53 10.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 GAK67947.1 - 0.00012 21.5 0.0 0.7 9.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 GAK67947.1 - 0.00014 21.8 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain UPF0079 PF02367.12 GAK67947.1 - 0.00015 21.4 0.0 0.035 13.7 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 GAK67947.1 - 0.00016 20.5 0.0 0.09 11.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus SKI PF01202.17 GAK67947.1 - 0.00029 20.7 0.0 0.78 9.5 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase NACHT PF05729.7 GAK67947.1 - 0.00068 19.3 1.5 0.73 9.4 0.1 3.7 3 1 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 GAK67947.1 - 0.00092 18.8 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 GAK67947.1 - 0.0015 18.4 0.0 0.047 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NB-ARC PF00931.17 GAK67947.1 - 0.0023 16.8 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 GAK67947.1 - 0.0024 17.4 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 GAK67947.1 - 0.007 15.5 0.0 2 7.4 0.0 2.4 2 0 0 2 2 2 1 KaiC Cytidylate_kin2 PF13189.1 GAK67947.1 - 0.0071 16.2 0.0 0.5 10.2 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.10 GAK67947.1 - 0.0088 15.7 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 1 NTPase PhoH PF02562.11 GAK67947.1 - 0.015 14.4 0.1 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein KTI12 PF08433.5 GAK67947.1 - 0.017 14.3 0.1 0.33 10.1 0.0 2.5 2 1 0 2 2 2 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 GAK67947.1 - 0.028 14.0 1.8 0.38 10.4 0.0 3.2 3 1 0 3 3 3 0 Adenylylsulphate kinase Zot PF05707.7 GAK67947.1 - 0.031 13.7 1.4 11 5.3 0.2 4.1 4 1 0 4 4 4 0 Zonular occludens toxin (Zot) ATP-synt_ab PF00006.20 GAK67947.1 - 0.045 13.2 0.0 7.1 6.0 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 GAK67947.1 - 0.045 14.0 0.2 18 5.6 0.1 3.2 2 1 0 3 3 2 0 ABC transporter AAA_24 PF13479.1 GAK67947.1 - 0.077 12.5 2.4 4.2 6.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.10 GAK67947.1 - 0.1 11.2 0.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_31 PF13614.1 GAK67947.1 - 0.11 12.4 0.0 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAK67947.1 - 0.16 11.4 0.4 6.3 6.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Bac_DnaA PF00308.13 GAK67947.1 - 0.29 10.7 0.0 21 4.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein eRF1_2 PF03464.10 GAK67948.1 - 2.3e-45 154.1 0.0 5.9e-45 152.8 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAK67948.1 - 1.6e-37 128.1 0.1 3.3e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 GAK67948.1 - 3.4e-26 91.3 0.0 6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 DUF1227 PF06777.6 GAK67949.1 - 5.7e-60 201.2 0.1 1e-59 200.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 GAK67949.1 - 1.8e-46 157.6 0.0 3.5e-41 140.5 0.0 2.4 2 0 0 2 2 2 2 DEAD_2 Helicase_C_2 PF13307.1 GAK67949.1 - 3.2e-45 154.1 0.0 7.3e-45 152.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 GAK67949.1 - 0.0021 17.5 0.0 0.99 8.8 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 GAK67949.1 - 0.0056 16.5 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YtxC PF08812.6 GAK67949.1 - 0.069 12.6 0.4 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 YtxC-like family Mitofilin PF09731.4 GAK67949.1 - 0.12 11.0 0.4 0.2 10.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SNF2_N PF00176.18 GAK67949.1 - 0.17 10.6 0.0 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF4604 PF15377.1 GAK67951.1 - 4.4e-17 62.7 19.3 8.4e-17 61.8 13.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) MRFAP1 PF15155.1 GAK67951.1 - 0.12 12.7 0.3 0.12 12.7 0.2 2.0 2 0 0 2 2 2 0 MORF4 family-associated protein1 K_channel_TID PF07941.6 GAK67951.1 - 0.77 10.0 6.3 0.065 13.4 0.9 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain EHN PF06441.7 GAK67952.1 - 1.9e-29 101.8 0.2 6.3e-29 100.1 0.0 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 GAK67952.1 - 2e-09 37.3 1.1 5.5e-09 35.9 0.0 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAK67952.1 - 4.1e-08 33.3 12.6 7.7e-08 32.4 6.4 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 GAK67952.1 - 0.00035 20.6 0.0 0.00061 19.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NUC173 PF08161.7 GAK67953.1 - 5.4e-51 172.7 0.1 6.3e-50 169.2 0.0 2.7 2 1 0 2 2 2 1 NUC173 domain Cnd1 PF12717.2 GAK67953.1 - 0.0033 17.2 0.4 0.27 11.0 0.1 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 GAK67953.1 - 0.43 9.2 5.2 0.56 8.8 0.2 2.8 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal HMGL-like PF00682.14 GAK67954.1 - 1.5e-61 208.1 0.0 2.5e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Rib_5-P_isom_A PF06026.9 GAK67954.1 - 7.8e-53 178.3 0.0 2.4e-52 176.7 0.0 1.8 2 0 0 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) LeuA_dimer PF08502.5 GAK67954.1 - 8.7e-20 70.8 0.8 9.4e-17 61.0 0.6 2.9 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Spo7 PF03907.8 GAK67955.1 - 4.8e-17 62.2 5.6 1.8e-16 60.3 3.9 1.7 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.4 GAK67955.1 - 0.023 14.6 2.4 0.037 14.0 0.2 2.0 2 0 0 2 2 2 0 Transmembrane protein 188 DUF2207 PF09972.4 GAK67955.1 - 0.14 10.6 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SOBP PF15279.1 GAK67955.1 - 0.79 10.0 7.6 1.3 9.3 5.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Sec10 PF07393.6 GAK67956.1 - 3.3e-82 276.8 0.0 7.3e-82 275.6 0.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec10 Mito_carr PF00153.22 GAK67956.1 - 2.3e-56 187.5 7.1 3.2e-24 84.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 GAK67956.1 - 7e-05 22.4 0.2 0.00018 21.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK67956.1 - 0.021 14.4 0.1 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain SET PF00856.23 GAK67957.1 - 1.2e-08 35.4 0.0 4.5e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF1365 PF07103.6 GAK67958.1 - 1.4e-23 83.3 1.8 2.4e-16 59.5 0.7 4.2 2 1 0 2 2 2 2 Protein of unknown function (DUF1365) Rep_fac-A_3 PF08661.6 GAK67959.1 - 2.1e-24 85.5 0.2 2.4e-24 85.3 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-like PF12869.2 GAK67959.1 - 0.026 14.0 0.2 0.033 13.6 0.2 1.2 1 0 0 1 1 1 0 tRNA_anti-like She9_MDM33 PF05546.6 GAK67960.1 - 4.1e-68 229.0 8.9 5.8e-68 228.5 6.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DRY_EERY PF09750.4 GAK67960.1 - 0.79 9.8 4.0 1.9 8.6 2.8 1.6 1 0 0 1 1 1 0 Alternative splicing regulator ATP-synt_D PF01813.12 GAK67961.1 - 3.9e-67 225.6 2.7 5.6e-67 225.1 1.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Sec62 PF03839.11 GAK67961.1 - 2.3 7.5 12.5 4.3 6.6 8.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Nop53 PF07767.6 GAK67961.1 - 4.9 6.0 21.7 0.16 10.8 10.8 1.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 GAK67961.1 - 5.1 5.0 14.9 8.1 4.3 10.3 1.3 1 0 0 1 1 1 0 CDC45-like protein GDC-P PF02347.11 GAK67962.1 - 4.8e-184 611.9 0.0 9.3e-170 564.9 0.0 3.0 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 GAK67962.1 - 1.1e-07 31.3 0.1 2.1e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase TRM PF02005.11 GAK67963.1 - 8.1e-37 127.0 0.4 7.1e-26 91.0 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Amino_oxidase PF01593.19 GAK67964.1 - 1.9e-15 56.8 0.0 4.9e-15 55.5 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAK67964.1 - 2e-13 49.9 1.2 1.2e-12 47.3 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAK67964.1 - 4.3e-12 45.8 0.6 1.3e-11 44.2 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAK67964.1 - 5.4e-06 25.5 1.2 0.00022 20.2 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAK67964.1 - 5.5e-06 26.3 0.1 0.0001 22.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK67964.1 - 1.4e-05 23.7 0.3 0.00039 19.0 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 GAK67964.1 - 0.0005 19.8 0.1 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 GAK67964.1 - 0.0016 17.6 0.0 0.0057 15.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 GAK67964.1 - 0.0023 17.3 1.2 0.0046 16.4 0.9 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 GAK67964.1 - 0.0036 17.4 0.4 0.46 10.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAK67964.1 - 0.0047 16.0 1.7 0.0062 15.6 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAK67964.1 - 0.01 16.2 10.1 0.031 14.6 0.2 2.9 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAK67964.1 - 0.02 13.5 3.5 0.81 8.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAK67964.1 - 0.033 13.9 2.8 0.055 13.2 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 GAK67964.1 - 0.035 13.1 0.3 0.069 12.2 0.2 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 GAK67964.1 - 0.039 13.9 0.2 0.091 12.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain GMC_oxred_N PF00732.14 GAK67964.1 - 0.073 12.2 0.2 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Rossmann-like PF10727.4 GAK67964.1 - 0.075 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_7 PF13241.1 GAK67964.1 - 0.078 13.2 0.3 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Glyco_trans_4_4 PF13579.1 GAK67964.1 - 0.092 12.8 0.1 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain F420_oxidored PF03807.12 GAK67964.1 - 0.096 13.1 0.3 0.27 11.6 0.2 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 GAK67964.1 - 0.11 12.4 1.0 0.27 11.2 0.7 1.6 1 0 0 1 1 1 0 NADH(P)-binding Lycopene_cycl PF05834.7 GAK67964.1 - 0.13 11.1 0.9 0.24 10.2 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.13 GAK67964.1 - 0.17 10.1 0.3 1.2 7.3 0.1 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 GAK67964.1 - 0.2 11.2 0.4 0.48 10.0 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 GAK67964.1 - 0.82 8.4 4.1 0.31 9.8 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Zn_clus PF00172.13 GAK67965.1 - 4.5e-07 29.6 11.2 8.4e-07 28.7 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK67965.1 - 3.2e-06 26.2 0.2 1.2e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain 4HBT PF03061.17 GAK67967.1 - 1.9e-09 37.4 0.0 3.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Amidohydro_5 PF13594.1 GAK67967.1 - 0.0025 17.5 0.0 0.008 15.9 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase 4HBT_3 PF13622.1 GAK67967.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Thioesterase-like superfamily Velvet PF11754.3 GAK67972.1 - 3.3e-26 92.1 0.0 4.9e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.3 GAK67973.1 - 1.5e-57 194.5 0.8 2.7e-57 193.6 0.0 1.8 2 1 0 2 2 2 1 Velvet factor UCH PF00443.24 GAK67975.1 - 1.6e-76 257.0 0.0 2.5e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAK67975.1 - 3.4e-17 62.8 0.0 3e-10 40.0 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 GAK67975.1 - 2.3e-16 60.0 0.0 6.6e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 GAK67975.1 - 0.0058 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal ubiquitin PF00240.18 GAK67975.1 - 0.18 11.2 0.1 0.42 10.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Zn-ribbon_8 PF09723.5 GAK67975.1 - 1.1 9.2 2.8 6.1 6.8 0.6 2.4 2 0 0 2 2 2 0 Zinc ribbon domain BCS1_N PF08740.6 GAK67976.1 - 8.7e-56 188.5 0.0 1.3e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAK67976.1 - 4.6e-17 62.4 0.0 8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAK67976.1 - 1.8e-05 25.5 0.0 3.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAK67976.1 - 0.00019 20.8 0.0 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAK67976.1 - 0.0052 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAK67976.1 - 0.0069 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 GAK67976.1 - 0.02 14.6 0.0 0.14 11.9 0.0 2.5 1 1 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 GAK67976.1 - 0.023 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 GAK67976.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 GAK67976.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 GAK67976.1 - 0.17 11.8 9.6 0.087 12.8 0.4 2.9 1 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 GAK67976.1 - 0.21 10.6 0.0 0.62 9.1 0.0 1.7 2 0 0 2 2 2 0 KaiC ATP_bind_3 PF01171.15 GAK67977.1 - 1.7e-15 56.9 0.0 3.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 PP-loop family DUF2616 PF11077.3 GAK67977.1 - 0.069 12.6 2.1 0.78 9.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) DUF4428 PF14471.1 GAK67977.1 - 0.073 12.8 1.0 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) WD40 PF00400.27 GAK67978.1 - 4.5e-15 54.8 15.5 7.7e-06 25.5 0.2 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_clus PF00172.13 GAK67979.1 - 1.3e-05 25.0 7.8 2.4e-05 24.1 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 GAK67980.1 - 5e-130 433.9 1.7 6.1e-130 433.6 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAK67980.1 - 8.5e-05 21.4 0.0 0.00012 20.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HORMA PF02301.13 GAK67981.1 - 1.5e-40 138.9 0.0 1.7e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Potex_coat PF06184.6 GAK67981.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Potexvirus coat protein zf-RING_2 PF13639.1 GAK67982.1 - 9.5e-10 38.1 9.7 9.5e-10 38.1 6.7 3.0 2 1 1 3 3 3 1 Ring finger domain zf-RING_3 PF14369.1 GAK67982.1 - 2.8e-09 36.8 0.8 2.8e-09 36.8 0.5 2.9 3 0 0 3 3 3 1 zinc-finger zf-rbx1 PF12678.2 GAK67982.1 - 3e-08 33.6 1.9 3e-08 33.6 1.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAK67982.1 - 4.3e-08 32.7 10.1 1.8e-05 24.3 0.3 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK67982.1 - 1.6e-05 24.8 1.2 1.6e-05 24.8 0.8 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK67982.1 - 0.0004 19.9 0.7 0.0004 19.9 0.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK67982.1 - 0.00042 19.9 14.7 0.00085 19.0 3.9 3.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAK67982.1 - 0.0016 18.2 3.2 0.0016 18.2 2.2 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 GAK67982.1 - 0.059 13.1 5.3 0.16 11.7 0.2 2.9 3 0 0 3 3 3 0 Double zinc ribbon zf-RING_4 PF14570.1 GAK67982.1 - 0.42 10.2 10.1 4.8 6.8 0.1 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-TFIIB PF13453.1 GAK67982.1 - 0.44 9.7 5.4 15 4.8 0.0 3.3 3 0 0 3 3 3 0 Transcription factor zinc-finger DUF4366 PF14283.1 GAK67982.1 - 0.55 9.6 3.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) HypA PF01155.14 GAK67982.1 - 0.8 9.4 3.1 0.87 9.2 0.1 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 GAK67982.1 - 1.3 9.0 7.7 5.3 7.0 0.5 3.2 3 0 0 3 3 3 0 Zinc ribbon domain His_Phos_1 PF00300.17 GAK67983.1 - 3.8e-18 66.0 0.0 6.5e-18 65.3 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GMP_synt_C PF00958.17 GAK67984.1 - 5e-40 135.1 0.0 1.1e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 GAK67984.1 - 3.4e-37 127.7 0.0 6.7e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 GAK67984.1 - 5.9e-12 45.0 0.1 1.4e-07 30.6 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 GAK67984.1 - 2.7e-10 40.0 0.0 5.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 GAK67984.1 - 6.1e-05 21.7 0.2 0.00011 20.8 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 GAK67984.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 GAK67984.1 - 0.00081 18.5 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 GAK67984.1 - 0.00095 18.7 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 GAK67984.1 - 0.0012 18.2 0.0 0.0077 15.5 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 GAK67984.1 - 0.012 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HOASN PF14515.1 GAK67984.1 - 0.065 13.6 0.7 0.16 12.3 0.2 1.8 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices DUF2392 PF10288.4 GAK67984.1 - 0.088 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 GAK67984.1 - 0.14 11.6 0.3 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 PP-loop family IF3_C PF00707.17 GAK67985.1 - 0.00013 21.6 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 GAK67985.1 - 0.0022 17.3 0.1 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.11 GAK67985.1 - 0.049 13.5 0.1 0.22 11.4 0.0 2.0 1 1 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain WD40 PF00400.27 GAK67986.1 - 1.7e-22 78.3 4.5 3.7e-07 29.7 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAK67986.1 - 0.0021 16.9 0.0 0.005 15.6 0.0 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Cys_Met_Meta_PP PF01053.15 GAK67987.1 - 8.2e-20 70.4 0.0 2.1e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme FliX PF10768.4 GAK67988.1 - 0.022 15.0 4.1 0.065 13.4 2.9 1.8 1 0 0 1 1 1 0 Class II flagellar assembly regulator MafB19-deam PF14437.1 GAK67988.1 - 0.076 12.6 3.3 0.17 11.4 2.3 1.6 1 0 0 1 1 1 0 MafB19-like deaminase ParA PF10609.4 GAK67989.1 - 6e-35 118.9 0.1 1.4e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAK67989.1 - 1.6e-10 40.7 0.6 0.00022 20.7 0.2 2.3 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 GAK67989.1 - 3e-05 23.2 0.2 0.0024 16.9 0.4 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_25 PF13481.1 GAK67989.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAK67989.1 - 0.03 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 VirE PF05272.6 GAK67989.1 - 0.084 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Virulence-associated protein E ABC2_membrane PF01061.19 GAK67990.1 - 2.8e-80 268.4 66.6 4.2e-43 146.9 18.0 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 GAK67990.1 - 3.6e-36 124.4 0.0 2.5e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAK67990.1 - 1.6e-34 117.6 2.3 6.9e-32 109.1 0.2 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 GAK67990.1 - 3.2e-12 46.3 0.1 3.8e-11 42.9 0.0 2.5 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAK67990.1 - 5e-07 29.3 0.1 0.0007 19.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAK67990.1 - 2e-05 23.8 0.1 6.7e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAK67990.1 - 0.00013 22.0 0.0 0.031 14.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 GAK67990.1 - 0.00026 20.6 0.3 0.095 12.3 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 GAK67990.1 - 0.00048 20.1 0.2 0.0093 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 GAK67990.1 - 0.0025 17.5 0.0 1.3 8.8 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain AAA_29 PF13555.1 GAK67990.1 - 0.0036 16.8 0.4 0.017 14.6 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 GAK67990.1 - 0.0079 15.8 0.1 0.3 10.7 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 GAK67990.1 - 0.011 15.6 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAK67990.1 - 0.014 14.8 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 GAK67990.1 - 0.021 14.2 0.7 0.14 11.5 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 GAK67990.1 - 0.034 13.1 61.8 0.19 10.7 17.9 4.4 3 2 0 3 3 3 0 ABC-2 family transporter protein AAA_17 PF13207.1 GAK67990.1 - 0.053 14.3 0.2 0.84 10.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 GAK67990.1 - 0.057 13.6 0.1 3 8.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 GAK67990.1 - 0.058 12.6 0.0 2.4 7.3 0.0 2.9 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 GAK67990.1 - 0.065 13.7 0.0 2.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 GAK67990.1 - 0.084 11.9 0.0 0.61 9.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 GAK67990.1 - 0.1 12.9 0.0 0.85 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAK67990.1 - 0.15 12.3 0.0 0.56 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 GAK67990.1 - 0.23 11.4 2.4 16 5.4 0.0 4.1 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit NAD_binding_4 PF07993.7 GAK67991.1 - 8e-14 51.1 0.1 5.9e-12 45.0 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAK67991.1 - 2.6e-13 49.9 0.2 7.9e-13 48.3 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK67991.1 - 6e-11 41.5 0.0 1.6e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAK67991.1 - 0.021 14.5 1.2 0.23 11.0 0.5 2.5 2 1 0 2 2 2 0 KR domain NmrA PF05368.8 GAK67991.1 - 0.05 12.8 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 2_5_RNA_ligase2 PF13563.1 GAK67992.1 - 5e-21 75.0 1.1 7e-21 74.5 0.8 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 GAK67992.1 - 0.0027 17.6 0.2 0.4 10.6 0.2 2.7 1 1 0 1 1 1 1 LigT like Phosphoesterase 2-Hacid_dh_C PF02826.14 GAK67993.1 - 3.6e-40 136.9 0.0 4.1e-39 133.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAK67993.1 - 2.5e-26 91.7 0.0 1.4e-25 89.3 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 GAK67993.1 - 5e-05 23.6 0.0 0.00014 22.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAK67993.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Mito_carr PF00153.22 GAK67994.1 - 4.9e-55 183.2 7.6 5.6e-20 70.8 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein Gly-zipper_OmpA PF13436.1 GAK67994.1 - 0.083 12.5 10.8 0.079 12.6 3.7 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF389 PF04087.9 GAK67994.1 - 2.2 8.1 6.7 0.14 12.1 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Zip PF02535.17 GAK67995.1 - 4.3e-32 111.3 20.6 4.3e-32 111.3 14.3 2.8 2 1 0 2 2 2 1 ZIP Zinc transporter DUF4514 PF14986.1 GAK67995.1 - 0.19 11.5 2.7 0.29 10.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) DUF3980 PF13140.1 GAK67995.1 - 4.6 7.5 10.1 0.38 11.0 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3980) ADC PF06314.6 GAK67996.1 - 1.8e-17 63.4 0.1 3e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Cupin_2 PF07883.6 GAK67997.1 - 3.4e-05 23.2 0.0 6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Peroxidase_2 PF01328.12 GAK67998.1 - 2.1e-16 59.5 0.0 2.9e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 HEAT_2 PF13646.1 GAK67999.1 - 0.0048 17.1 14.2 0.02 15.1 0.6 4.8 4 1 1 5 5 5 2 HEAT repeats TPR_19 PF14559.1 GAK67999.1 - 0.19 12.0 6.2 0.61 10.4 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat FoP_duplication PF13865.1 GAK68000.1 - 0.85 10.1 4.9 1.5 9.3 3.4 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Transferase PF02458.10 GAK68001.1 - 0.00059 18.3 0.0 0.055 11.8 0.0 2.1 2 0 0 2 2 2 2 Transferase family Condensation PF00668.15 GAK68001.1 - 0.073 11.9 0.0 2.6 6.8 0.0 2.5 1 1 2 3 3 3 0 Condensation domain MFS_1 PF07690.11 GAK68002.1 - 7.1e-36 123.6 53.8 1.8e-35 122.3 35.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAK68002.1 - 1.5e-10 40.2 14.9 1.5e-10 40.2 10.3 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAK68002.1 - 7.6e-07 27.7 22.0 1e-06 27.2 15.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Corona_S2 PF01601.11 GAK68002.1 - 5.1 5.0 5.4 2.1 6.3 1.8 1.7 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein Tri3 PF07428.6 GAK68003.1 - 0.015 14.0 0.2 0.024 13.3 0.2 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Con-6 PF10346.4 GAK68004.1 - 0.043 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Conidiation protein 6 Glyco_transf_28 PF03033.15 GAK68006.1 - 0.00074 19.2 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAK68006.1 - 0.033 12.7 0.0 0.13 10.7 0.0 1.8 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase FA_hydroxylase PF04116.8 GAK68007.1 - 1.7e-14 54.1 7.5 1.7e-14 54.1 5.2 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Thioredoxin_8 PF13905.1 GAK68007.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like SKN1 PF03935.10 GAK68011.1 - 3.4e-188 625.8 1.9 4.8e-188 625.3 1.3 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 GAK68011.1 - 1.5e-06 27.6 2.3 0.0038 16.5 0.1 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 4HBT PF03061.17 GAK68012.1 - 2.1e-07 30.9 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Actin PF00022.14 GAK68012.1 - 0.042 12.2 0.0 0.065 11.6 0.0 1.2 1 0 0 1 1 1 0 Actin GILT PF03227.11 GAK68013.1 - 5.6e-07 29.3 0.2 1.2e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) zf-RING_2 PF13639.1 GAK68015.1 - 3.1e-09 36.4 19.9 1.7e-07 30.9 2.1 3.4 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 GAK68015.1 - 7.7e-06 25.4 9.7 5e-05 22.8 0.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAK68015.1 - 1.3e-05 25.1 8.1 9.3e-05 22.4 0.1 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAK68015.1 - 0.0009 19.2 12.7 0.0027 17.6 1.1 3.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK68015.1 - 0.0035 16.9 11.4 0.062 12.9 0.5 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAK68015.1 - 0.0044 16.8 5.9 0.0044 16.8 0.3 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 GAK68015.1 - 0.012 15.3 10.6 0.025 14.2 0.3 3.2 3 0 0 3 3 3 0 zinc-RING finger domain RINGv PF12906.2 GAK68015.1 - 0.77 9.8 9.4 0.11 12.5 1.7 2.5 2 0 0 2 2 2 0 RING-variant domain UPF0547 PF10571.4 GAK68015.1 - 1.5 8.6 4.5 2.4 7.9 0.2 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Aa_trans PF01490.13 GAK68016.1 - 4e-05 22.2 5.7 0.00098 17.7 3.6 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF3533 PF12051.3 GAK68017.1 - 4.5e-100 335.0 15.2 5.2e-100 334.8 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) UPF0233 PF06781.7 GAK68017.1 - 0.099 12.2 2.5 14 5.4 0.0 3.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Aldolase_II PF00596.16 GAK68018.1 - 1.1e-23 83.8 0.0 1.5e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Abhydrolase_6 PF12697.2 GAK68019.1 - 2.2e-09 37.5 0.1 6.4e-09 36.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK68019.1 - 1.7e-07 31.1 0.0 2.9e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAK68019.1 - 0.00017 21.2 0.0 0.00031 20.3 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 GAK68019.1 - 0.00024 20.8 0.0 0.00056 19.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 GAK68019.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ribonuc_red_sm PF00268.16 GAK68020.1 - 3e-117 390.6 1.2 3.6e-117 390.3 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain 3Beta_HSD PF01073.14 GAK68021.1 - 1.3e-16 60.1 0.0 2.2e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAK68021.1 - 4.4e-16 59.0 0.0 7.8e-16 58.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAK68021.1 - 8e-14 52.0 0.1 2.2e-13 50.6 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAK68021.1 - 1.1e-13 50.6 0.0 4e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAK68021.1 - 8.7e-07 28.4 0.1 1.2e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 GAK68021.1 - 2.5e-05 24.2 0.1 6.7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAK68021.1 - 0.0018 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 GAK68021.1 - 0.0028 17.3 0.0 0.0086 15.7 0.0 1.8 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 GAK68021.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UPF0075 PF03702.9 GAK68024.1 - 7.7e-88 294.8 0.0 9e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) BcrAD_BadFG PF01869.15 GAK68024.1 - 0.04 13.2 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Sugar_tr PF00083.19 GAK68025.1 - 7.8e-87 291.7 24.0 9.3e-87 291.4 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK68025.1 - 1.5e-31 109.3 45.8 1.2e-24 86.7 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAK68026.1 - 6.7e-17 61.2 0.2 9.4e-17 60.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK68026.1 - 0.00017 21.4 8.9 0.00032 20.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb2_6 PF00562.23 GAK68027.1 - 7.4e-125 416.6 0.3 8.7e-125 416.4 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 GAK68027.1 - 2e-27 95.2 0.0 3.7e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 GAK68027.1 - 2e-09 37.2 0.4 4.5e-09 36.1 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 GAK68027.1 - 0.02 14.7 0.3 0.034 13.9 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Acetyltransf_1 PF00583.19 GAK68030.1 - 3.2e-10 39.9 0.0 4.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAK68030.1 - 7.2e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAK68030.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAK68030.1 - 0.0017 18.2 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAK68030.1 - 0.034 14.2 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Prenyltrans PF00432.16 GAK68031.1 - 1.6e-50 168.3 7.7 3.9e-11 42.2 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAK68031.1 - 6e-32 110.3 0.0 1.1e-12 48.3 0.0 3.7 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAK68031.1 - 9.3e-09 35.2 0.0 1e-06 28.6 0.0 3.0 1 1 2 3 3 3 1 Prenyltransferase-like MutS_V PF00488.16 GAK68032.1 - 2.2e-71 240.0 0.0 3.5e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAK68032.1 - 3.4e-36 124.9 2.9 8e-36 123.7 2.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAK68032.1 - 2.9e-21 75.5 0.0 9.5e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 GAK68032.1 - 2.2e-12 47.2 0.0 1.1e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 GAK68032.1 - 5.1e-11 42.6 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV Dicty_REP PF05086.7 GAK68032.1 - 2.1 6.0 2.9 3 5.4 2.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C2H2 PF00096.21 GAK68033.1 - 3e-08 33.5 14.4 2.6e-05 24.2 1.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAK68033.1 - 2e-06 27.7 3.0 2e-06 27.7 2.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 GAK68033.1 - 0.00038 20.5 3.0 0.011 15.9 0.2 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAK68033.1 - 0.002 18.2 0.1 0.002 18.2 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 GAK68033.1 - 0.0027 17.9 0.7 0.0027 17.9 0.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger ORC6 PF05460.8 GAK68034.1 - 0.054 12.5 6.7 0.33 10.0 4.7 1.8 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF566 PF04484.7 GAK68034.1 - 8.7 5.7 10.9 12 5.3 7.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) tRNA-synt_2 PF00152.15 GAK68035.1 - 8.4e-79 264.7 0.1 1.2e-78 264.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAK68035.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAK68035.1 - 0.048 12.8 0.3 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) RRM_6 PF14259.1 GAK68036.1 - 7e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK68036.1 - 0.00015 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidase02_C PF12123.3 GAK68036.1 - 0.032 13.8 0.1 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase RRM_5 PF13893.1 GAK68036.1 - 0.053 13.3 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 GAK68036.1 - 0.3 10.4 11.3 0.43 9.9 7.8 1.2 1 0 0 1 1 1 0 Vta1 like AlaDh_PNT_N PF05222.10 GAK68037.1 - 9.3e-27 93.6 0.0 1.5e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 GAK68037.1 - 4e-07 29.7 0.0 7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lung_7-TM_R PF06814.8 GAK68038.1 - 6.2e-51 173.0 14.1 1.4e-50 171.9 9.8 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor Ribosomal_L32p PF01783.18 GAK68038.1 - 2.8e-12 46.6 5.9 4.9e-12 45.8 4.1 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family ABC2_membrane_4 PF12730.2 GAK68038.1 - 5.6 6.0 27.7 0.17 11.0 13.0 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein GLTSCR1 PF15249.1 GAK68039.1 - 4.8e-09 36.2 0.6 4.8e-09 36.2 0.4 2.4 2 1 0 2 2 2 1 Glioma tumor suppressor candidate region PEMT PF04191.8 GAK68039.1 - 5e-05 23.3 2.3 9.5e-05 22.4 1.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Glyco_hydro_cc PF11790.3 GAK68039.1 - 0.34 10.2 0.0 0.55 9.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core TauD PF02668.11 GAK68042.1 - 6.1e-53 180.1 0.2 9.5e-53 179.4 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPP_enzyme_N PF02776.13 GAK68043.1 - 2.9e-35 121.2 0.1 4.2e-35 120.7 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAK68043.1 - 2.1e-27 95.5 0.0 4.4e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAK68043.1 - 4.6e-14 52.2 0.0 2.7e-13 49.7 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aldo_ket_red PF00248.16 GAK68044.1 - 1.1e-54 185.1 0.1 1.3e-54 184.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BRAP2 PF07576.7 GAK68045.1 - 2.6e-24 84.9 0.1 5.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 GAK68045.1 - 6.7e-19 67.7 5.2 6.7e-19 67.7 3.6 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 GAK68045.1 - 8.6e-09 35.0 10.3 8.6e-09 35.0 7.2 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 GAK68045.1 - 4.1e-05 23.2 8.2 4.1e-05 23.2 5.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAK68045.1 - 9e-05 22.0 8.8 9e-05 22.0 6.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK68045.1 - 0.00011 22.1 9.9 0.00011 22.1 6.8 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAK68045.1 - 0.00078 19.5 6.6 0.00078 19.5 4.6 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAK68045.1 - 0.0018 17.9 4.2 0.0054 16.4 1.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger RRM_6 PF14259.1 GAK68045.1 - 0.0027 17.6 0.1 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-Apc11 PF12861.2 GAK68045.1 - 0.016 15.0 5.2 0.043 13.6 3.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAK68045.1 - 0.045 13.3 5.8 0.12 11.9 4.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 GAK68045.1 - 0.095 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_13 PF13166.1 GAK68045.1 - 0.16 10.4 4.1 0.23 9.8 2.8 1.1 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.6 GAK68045.1 - 0.37 10.2 11.3 4.5 6.6 7.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 MbeD_MobD PF04899.7 GAK68045.1 - 0.6 10.0 6.3 0.57 10.1 0.2 2.7 2 0 0 2 2 2 0 MbeD/MobD like IncA PF04156.9 GAK68045.1 - 0.86 9.1 13.0 1.8 8.1 9.0 1.4 1 0 0 1 1 1 0 IncA protein DUF4200 PF13863.1 GAK68045.1 - 2.5 8.0 12.6 6.4 6.7 8.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 GAK68045.1 - 3 6.7 8.5 4.7 6.0 5.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 GAK68045.1 - 5.1 7.4 8.2 2.8 8.3 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CDC14 PF08045.6 GAK68046.1 - 0.00024 20.3 0.2 0.015 14.4 0.1 2.5 3 0 0 3 3 3 2 Cell division control protein 14, SIN component GCS PF03074.11 GAK68048.1 - 8.6e-164 544.9 0.0 4e-130 434.1 0.0 2.1 1 1 1 2 2 2 2 Glutamate-cysteine ligase UPF0278 PF08745.6 GAK68048.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 UPF0278 family DUF1769 PF08588.5 GAK68049.1 - 7.8e-25 86.5 0.2 2e-24 85.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) KH_1 PF00013.24 GAK68050.1 - 2.3e-09 36.7 0.0 9.3e-07 28.4 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 GAK68050.1 - 2.3e-05 23.8 3.9 0.00025 20.6 0.2 2.7 2 0 0 2 2 2 1 KH domain PALP PF00291.20 GAK68050.1 - 0.0028 16.9 1.1 0.0051 16.0 0.7 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_repressor PF01371.14 GAK68050.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein PGI PF00342.14 GAK68051.1 - 2.1e-210 699.2 0.4 2.5e-210 698.9 0.2 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase HNH_3 PF13392.1 GAK68053.1 - 1.1e-07 31.1 2.5 1.3e-07 30.9 0.1 2.3 2 1 0 2 2 2 1 HNH endonuclease MFS_1 PF07690.11 GAK68054.1 - 3.1e-23 82.0 43.2 5.9e-18 64.6 11.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2370 PF10176.4 GAK68054.1 - 1.4 8.1 7.9 1.1 8.5 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) GATA PF00320.22 GAK68055.1 - 3.8 6.9 7.0 2.2 7.7 0.2 2.7 2 0 0 2 2 2 0 GATA zinc finger VPS9 PF02204.13 GAK68056.1 - 3.7e-13 49.4 0.0 6.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF455 PF04305.9 GAK68057.1 - 2.1e-99 331.9 0.0 3.1e-99 331.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 GAK68057.1 - 2.4e-07 30.2 0.5 5.3e-07 29.1 0.3 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 GAK68057.1 - 0.027 14.1 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain zf-C3HC4_3 PF13920.1 GAK68058.1 - 2.7e-10 39.7 3.9 4.2e-10 39.1 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK68058.1 - 7.3e-06 25.9 2.4 1.5e-05 24.8 1.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAK68058.1 - 9.2e-06 25.2 3.2 1.6e-05 24.4 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAK68058.1 - 5.4e-05 22.9 5.7 9.8e-05 22.1 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAK68058.1 - 0.00034 20.2 3.4 0.00067 19.3 2.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain MKT1_C PF12246.3 GAK68060.1 - 2.7e-69 232.8 0.0 2.8e-68 229.5 0.0 2.0 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 GAK68060.1 - 3.4e-26 91.4 0.0 6.2e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 GAK68060.1 - 1.5e-07 31.3 0.0 3.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAK68060.1 - 2.7e-07 30.7 0.0 5.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Hydantoinase_A PF01968.13 GAK68061.1 - 1.5e-87 293.3 1.8 2.7e-87 292.5 1.3 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAK68061.1 - 1.1e-51 174.7 0.0 1.7e-49 167.6 0.0 2.7 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Pkinase PF00069.20 GAK68062.1 - 1.3e-31 109.7 0.0 2.6e-31 108.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68062.1 - 1.5e-14 53.6 0.0 1.1e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK68062.1 - 0.00028 19.9 0.0 0.0099 14.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF2249 PF10006.4 GAK68063.1 - 0.41 10.2 2.0 58 3.3 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2249) PAPA-1 PF04795.7 GAK68064.1 - 5.4e-15 55.8 8.8 5.4e-15 55.8 6.1 4.9 3 3 1 4 4 4 1 PAPA-1-like conserved region Ras PF00071.17 GAK68065.1 - 3.7e-35 120.7 0.1 4.5e-35 120.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAK68065.1 - 3e-22 79.3 0.0 1.3e-21 77.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAK68065.1 - 9.3e-08 31.5 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAK68065.1 - 3.8e-07 29.4 0.1 4.9e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAK68065.1 - 0.00023 20.6 0.0 0.0017 17.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAK68065.1 - 0.0068 16.3 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.6 GAK68065.1 - 0.031 12.9 0.4 0.58 8.7 0.0 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 GAK68065.1 - 0.057 12.0 0.2 0.14 10.8 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 GAK68065.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNB PF00773.14 GAK68066.1 - 1.3e-48 165.9 0.0 2.2e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 RNB domain LtrA PF06772.6 GAK68066.1 - 5.3e-18 65.0 11.1 3.7e-09 35.9 4.7 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF2207 PF09972.4 GAK68066.1 - 0.12 10.9 0.3 0.2 10.1 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pex14_N PF04695.8 GAK68067.1 - 1.8 8.6 7.6 4 7.4 5.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serglycin PF04360.7 GAK68067.1 - 2.5 7.8 17.9 9.7 5.9 12.4 2.2 1 1 0 1 1 1 0 Serglycin Macoilin PF09726.4 GAK68067.1 - 2.9 6.0 17.4 3.4 5.8 12.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 GAK68067.1 - 6.4 6.2 10.8 8.1 5.8 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal NUDIX PF00293.23 GAK68069.1 - 4.2e-10 39.3 0.0 1.6e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 NUDIX domain Exo_endo_phos PF03372.18 GAK68070.1 - 9.3e-25 87.9 0.1 2.2e-24 86.7 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 GAK68070.1 - 0.0001 22.0 2.5 0.017 14.9 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat CN_hydrolase PF00795.17 GAK68071.1 - 4.2e-26 91.4 0.0 6.8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sfi1 PF08457.5 GAK68073.1 - 3.6e-27 95.0 123.6 2.1e-24 85.8 67.6 2.7 1 1 1 2 2 2 2 Sfi1 spindle body protein PNK3P PF08645.6 GAK68075.1 - 0.049 13.0 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Pkinase PF00069.20 GAK68077.1 - 8.4e-67 225.0 0.0 1.3e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68077.1 - 1.7e-44 151.8 0.0 3e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 GAK68077.1 - 1.2e-24 86.2 0.0 2.3e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 GAK68077.1 - 9.6e-10 38.5 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAK68077.1 - 2.9e-08 33.4 0.0 6.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 GAK68077.1 - 6.2e-06 25.3 0.0 1.5e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAK68077.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RA PF00788.18 GAK68077.1 - 0.22 12.0 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Seadorna_VP7 PF07387.6 GAK68077.1 - 0.45 9.3 0.0 0.74 8.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4519 PF15012.1 GAK68077.1 - 1.3 8.9 3.9 2.4 8.1 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) ThuA PF06283.6 GAK68078.1 - 1.2e-69 234.3 2.9 1.7e-69 233.8 2.0 1.2 1 0 0 1 1 1 1 Trehalose utilisation UTP15_C PF09384.5 GAK68080.1 - 3.4e-48 163.0 0.0 5e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 GAK68080.1 - 2.4e-36 122.3 2.4 2e-10 40.1 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 GAK68080.1 - 0.0018 16.5 0.0 0.86 7.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Glyco_hydro_18 PF00704.23 GAK68081.1 - 8e-100 334.6 5.0 1.1e-99 334.2 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FAM101 PF15068.1 GAK68081.1 - 0.93 8.9 4.7 1.6 8.1 3.2 1.4 1 0 0 1 1 1 0 FAM101 family QRPTase_C PF01729.14 GAK68082.1 - 1.4e-43 148.3 0.1 2.4e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 GAK68082.1 - 1.2e-21 76.3 0.0 3.9e-21 74.6 0.0 2.0 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain TP6A_N PF04406.9 GAK68082.1 - 1.7e-16 59.6 0.0 3.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF1341 PF07071.6 GAK68082.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) PAP2 PF01569.16 GAK68083.1 - 1.7e-28 98.8 2.0 1.7e-28 98.8 1.4 1.9 2 1 0 2 2 2 1 PAP2 superfamily Colicin_V PF02674.11 GAK68083.1 - 0.047 13.5 3.7 1 9.1 0.2 2.6 3 0 0 3 3 3 0 Colicin V production protein TPPK_C PF12555.3 GAK68083.1 - 0.062 13.0 0.7 0.062 13.0 0.5 3.6 3 1 0 3 3 3 0 Thiamine pyrophosphokinase C terminal APG6 PF04111.7 GAK68084.1 - 1.3e-95 320.1 0.0 1.8e-95 319.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 HCMV_UL139 PF12507.3 GAK68084.1 - 0.029 14.5 1.6 0.064 13.4 1.1 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF812 PF05667.6 GAK68084.1 - 0.043 12.3 3.8 0.054 11.9 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ribonucleas_3_3 PF14622.1 GAK68085.1 - 3.9e-29 101.2 0.0 5.2e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAK68085.1 - 0.00024 21.5 0.0 0.00048 20.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain eIF3g PF12353.3 GAK68086.1 - 1.4e-44 151.1 5.8 2.2e-44 150.4 4.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 GAK68086.1 - 4.9e-19 67.7 0.0 9.2e-19 66.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK68086.1 - 1.8e-15 56.6 0.0 3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK68086.1 - 1.3e-09 37.7 0.0 4.2e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAK68086.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif vATP-synt_E PF01991.13 GAK68087.1 - 4.7e-59 199.0 14.0 5.5e-59 198.7 9.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Ran_BP1 PF00638.13 GAK68088.1 - 3.9e-22 78.5 0.1 8e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain DUF1188 PF06690.6 GAK68088.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) hDGE_amylase PF14701.1 GAK68089.1 - 2.9e-163 543.6 0.1 4e-163 543.2 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 GAK68089.1 - 4.1e-111 371.2 0.1 6.3e-111 370.6 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 GAK68089.1 - 1.3e-79 267.0 0.0 2.4e-79 266.2 0.0 1.5 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 GAK68089.1 - 3.1e-16 58.9 0.1 6.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 GAK68089.1 - 0.015 14.7 0.0 0.29 10.4 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, catalytic domain DUF3102 PF11300.3 GAK68089.1 - 0.088 12.8 0.6 1 9.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3102) Peptidase_S10 PF00450.17 GAK68090.1 - 1.2e-97 327.6 5.1 2.2e-97 326.8 3.5 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Ribosomal_L33 PF00471.15 GAK68090.1 - 5.7e-13 48.8 0.0 1.9e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 Ribosomal protein L33 ABC_membrane_2 PF06472.10 GAK68093.1 - 2.4e-98 328.7 4.6 3.4e-98 328.2 2.2 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAK68093.1 - 5.8e-16 59.0 0.0 1.8e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.7 GAK68093.1 - 0.0045 16.0 0.0 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 GAK68093.1 - 0.0069 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAK68093.1 - 0.02 15.6 0.0 0.061 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAK68093.1 - 0.021 14.7 0.0 0.072 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 GAK68093.1 - 0.023 14.2 0.0 0.072 12.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 GAK68093.1 - 0.026 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 GAK68093.1 - 0.029 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 GAK68093.1 - 0.055 13.7 0.3 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 GAK68093.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAK68093.1 - 0.079 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 GAK68093.1 - 0.093 10.0 0.0 0.16 9.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sigma54_activat PF00158.21 GAK68093.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.14 GAK68093.1 - 0.14 11.3 0.0 10 5.3 0.0 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain EGF_CA PF07645.10 GAK68094.1 - 0.059 13.3 0.5 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain Dockerin_1 PF00404.13 GAK68095.1 - 0.4 10.4 3.1 38 4.2 0.0 3.9 4 0 0 4 4 4 0 Dockerin type I repeat MFS_1 PF07690.11 GAK68096.1 - 4.6e-29 101.2 42.9 4.6e-29 101.2 29.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily His_Phos_2 PF00328.17 GAK68097.1 - 3.6e-43 148.2 0.0 5.1e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 GAK68098.1 - 1.4e-12 47.8 0.5 2.3e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK68098.1 - 6.3e-08 32.6 0.0 8.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 GAK68098.1 - 0.052 13.1 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol_Rpb6 PF01192.17 GAK68099.1 - 4.9e-24 83.8 0.2 7.1e-24 83.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Chitin_synth_1 PF01644.12 GAK68100.1 - 2.4e-73 245.2 0.2 3.5e-73 244.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 GAK68100.1 - 3.1e-23 81.9 0.0 3e-18 65.5 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 GAK68100.1 - 4.8e-23 80.6 0.0 1.3e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 GAK68100.1 - 1e-12 48.1 0.4 1e-12 48.1 0.3 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAK68100.1 - 3e-09 37.0 0.0 3.6e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Tautomerase_3 PF14832.1 GAK68101.1 - 1.9e-40 138.0 0.0 2.4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme DBD_Tnp_Mut PF03108.10 GAK68101.1 - 0.021 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase Zn_clus PF00172.13 GAK68102.1 - 8.8e-06 25.5 15.3 8.8e-06 25.5 10.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEX11 PF05648.9 GAK68103.1 - 3.1e-66 222.8 2.4 3.5e-66 222.6 1.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HemX PF04375.9 GAK68104.1 - 0.005 15.4 0.1 0.0057 15.2 0.1 1.1 1 0 0 1 1 1 1 HemX DUF4250 PF14056.1 GAK68104.1 - 0.13 12.0 1.6 3.6 7.3 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) WD40 PF00400.27 GAK68105.1 - 3.9e-20 70.9 11.5 1.7e-05 24.4 0.4 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat GTP_EFTU PF00009.22 GAK68106.1 - 1.8e-62 210.1 0.2 2.8e-62 209.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAK68106.1 - 1.4e-36 124.6 0.0 3.9e-36 123.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAK68106.1 - 9.8e-22 76.6 0.0 2.2e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 GAK68106.1 - 1.3e-13 50.5 0.0 3.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 GAK68106.1 - 2.6e-13 49.8 0.0 7.5e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAK68106.1 - 4.5e-06 26.6 0.1 8.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ECH PF00378.15 GAK68107.1 - 3.2e-21 75.5 3.8 3.3e-12 46.0 0.0 2.6 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAK68107.1 - 7.2e-16 58.4 0.0 2.9e-15 56.4 0.0 2.0 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region DMRL_synthase PF00885.14 GAK68110.1 - 6.7e-42 142.5 0.0 3.8e-24 84.9 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase GST_C PF00043.20 GAK68111.1 - 8.7e-13 48.0 0.0 1.9e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAK68111.1 - 1.2e-07 32.0 0.1 2.1e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAK68111.1 - 2.5e-07 30.8 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAK68111.1 - 6.4e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAK68111.1 - 6.8e-06 25.8 0.0 1.9e-05 24.4 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAK68111.1 - 0.0037 17.2 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NAC PF01849.13 GAK68112.1 - 2.6e-20 71.6 0.0 4.2e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 NAC domain ATP-synt_E PF05680.7 GAK68113.1 - 7.8e-26 89.8 0.4 8.1e-26 89.8 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain ABC_trans_N PF14510.1 GAK68113.1 - 0.084 12.9 0.1 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal OEP PF02321.13 GAK68113.1 - 0.23 11.0 1.9 0.3 10.6 1.3 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein BRCA2 PF00634.13 GAK68114.1 - 1 8.6 3.9 5.7 6.3 0.1 2.6 3 0 0 3 3 3 0 BRCA2 repeat WES_acyltransf PF03007.11 GAK68116.1 - 1.6e-14 54.0 0.0 1.6e-14 54.0 0.0 2.0 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain WD40 PF00400.27 GAK68117.1 - 1.8e-48 160.7 29.8 2.1e-11 43.2 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 GAK68117.1 - 2.5e-28 98.9 0.0 4.8e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 GAK68117.1 - 0.23 11.1 0.0 1.9 8.1 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Metallophos PF00149.23 GAK68118.1 - 1.4e-43 148.6 0.1 1.7e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rad51 PF08423.6 GAK68119.1 - 4.1e-10 39.0 0.2 2.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.1 GAK68119.1 - 7.2e-10 38.5 0.2 1.7e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAK68119.1 - 0.0014 17.7 0.3 0.0043 16.1 0.0 1.9 2 0 0 2 2 2 1 KaiC RecA PF00154.16 GAK68119.1 - 0.0017 17.4 0.5 0.057 12.4 0.1 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Amino_oxidase PF01593.19 GAK68120.1 - 1.2e-11 44.3 0.0 1.2e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAK68120.1 - 7.3e-10 38.7 0.1 1.5e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAK68120.1 - 1.9e-05 24.8 0.1 4.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK68120.1 - 0.025 14.3 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAK68120.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAK68120.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HtaA PF04213.8 GAK68120.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Htaa HI0933_like PF03486.9 GAK68120.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Hexokinase_2 PF03727.11 GAK68121.1 - 2.5e-77 259.3 0.0 3.6e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAK68121.1 - 3.8e-64 215.8 0.0 6.4e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase YjgF_endoribonc PF14588.1 GAK68121.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Aldo_ket_red PF00248.16 GAK68122.1 - 6.1e-48 163.0 0.0 7.7e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AA_permease PF00324.16 GAK68124.1 - 5.5e-129 430.5 38.0 6.8e-129 430.2 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAK68124.1 - 2.3e-36 125.2 41.2 3e-36 124.8 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_8 PF13621.1 GAK68124.1 - 1.9e-33 116.0 0.0 6.4e-33 114.2 0.0 1.8 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 GAK68124.1 - 2.1e-05 23.9 0.6 8.9e-05 21.8 0.0 2.2 2 1 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 GAK68124.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase G-patch_2 PF12656.2 GAK68125.1 - 1.5e-26 91.9 0.8 1.4e-25 88.9 0.4 2.8 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 GAK68125.1 - 3e-05 23.6 7.8 6.3e-05 22.6 5.4 1.5 1 0 0 1 1 1 1 G-patch domain SRF-TF PF00319.13 GAK68126.1 - 0.0081 15.3 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF747 PF05346.6 GAK68127.1 - 2e-122 408.3 3.4 2.6e-122 408.0 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family TypeIII_RM_meth PF12564.3 GAK68127.1 - 0.059 13.3 1.6 0.16 11.9 1.1 1.8 1 1 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit Pol_alpha_B_N PF08418.5 GAK68129.1 - 0.33 10.4 6.4 0.45 10.0 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF755 PF05501.6 GAK68129.1 - 3.7 7.6 13.6 0.081 12.9 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) tRNA_m1G_MT PF01746.16 GAK68130.1 - 2.9e-25 88.9 0.0 1.6e-20 73.5 0.0 2.5 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase PEHE PF15275.1 GAK68130.1 - 0.8 10.1 5.3 1.5 9.3 1.2 2.5 2 0 0 2 2 2 0 PEHE domain DUF2036 PF09724.4 GAK68131.1 - 3.2e-53 180.9 0.0 3.8e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF2893 PF11459.3 GAK68131.1 - 0.01 15.5 1.4 0.015 15.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) CAV_VP3 PF04771.7 GAK68131.1 - 0.071 13.0 1.2 8.5 6.3 0.1 2.5 2 0 0 2 2 2 0 Chicken anaemia virus VP-3 protein bZIP_1 PF00170.16 GAK68133.1 - 0.0016 18.3 22.5 0.0017 18.2 13.7 2.3 2 1 0 2 2 2 1 bZIP transcription factor Ldh_1_C PF02866.13 GAK68134.1 - 1.7e-42 145.0 0.0 2.7e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 GAK68134.1 - 1.1e-41 141.9 0.2 6.2e-28 97.3 0.0 2.2 2 0 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 GAK68134.1 - 0.017 14.4 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.14 GAK68134.1 - 0.024 13.3 0.0 0.038 12.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 GAK68134.1 - 0.12 11.4 0.7 1.6 7.8 0.1 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldo_ket_red PF00248.16 GAK68135.1 - 7e-56 189.1 0.0 9.1e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Dioxygenase_C PF00775.16 GAK68138.1 - 1.2e-09 37.6 0.0 2.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Dioxygenase p450 PF00067.17 GAK68139.1 - 1e-28 100.0 0.0 1.9e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAK68140.1 - 2e-12 46.5 22.8 2e-12 46.5 15.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3169 PF11368.3 GAK68140.1 - 0.26 10.4 4.9 0.14 11.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Lactamase_B_2 PF12706.2 GAK68141.1 - 2.4e-13 50.0 0.0 3.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAK68141.1 - 1.3e-09 37.9 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Sel1 PF08238.7 GAK68142.1 - 3e-16 59.4 9.7 0.00021 21.8 0.1 6.0 6 0 0 6 6 6 4 Sel1 repeat TPR_5 PF12688.2 GAK68142.1 - 0.062 13.3 0.7 9.4 6.3 0.0 2.8 3 0 0 3 3 3 0 Tetratrico peptide repeat Ipi1_N PF12333.3 GAK68143.1 - 1.9e-15 56.6 1.6 1.2e-09 37.9 0.0 4.9 4 0 0 4 4 4 3 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 GAK68143.1 - 0.035 14.5 0.1 0.035 14.5 0.1 3.4 3 0 0 3 3 3 0 HEAT-like repeat Complex1_LYR PF05347.10 GAK68144.1 - 0.11 12.2 2.0 0.48 10.2 1.2 2.1 2 1 0 2 2 2 0 Complex 1 protein (LYR family) eIF2A PF08662.6 GAK68145.1 - 3.1e-42 144.4 0.0 3.7e-37 127.9 0.0 4.4 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 GAK68145.1 - 6.7e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAK68145.1 - 2.8e-05 23.6 0.1 7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK68145.1 - 0.00036 20.3 0.1 0.00093 19.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 GAK68145.1 - 0.00077 19.2 3.3 0.23 11.3 0.0 5.3 7 0 0 7 7 7 1 WD domain, G-beta repeat 4HB_MCP_1 PF12729.2 GAK68145.1 - 0.59 9.4 8.6 0.97 8.7 5.9 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Spb1_C PF07780.7 GAK68146.1 - 1.5e-71 240.2 28.2 1.5e-71 240.2 19.6 4.5 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 GAK68146.1 - 1.4e-52 178.2 0.0 3.1e-52 177.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 GAK68146.1 - 2.2e-51 173.5 9.6 2.2e-51 173.5 6.6 5.4 3 2 1 4 4 4 1 Domain of unknown function (DUF3381) DUF1751 PF08551.5 GAK68147.1 - 8.8e-28 96.5 3.7 1.7e-27 95.6 2.5 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) LRR_6 PF13516.1 GAK68147.1 - 9.6e-11 40.6 8.3 0.49 10.6 0.0 7.8 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 GAK68147.1 - 1.2e-06 28.0 11.6 0.00075 19.0 0.9 6.1 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAK68147.1 - 0.003 17.2 9.8 0.099 12.4 0.2 5.7 4 2 1 5 5 5 1 Leucine rich repeat LRR_7 PF13504.1 GAK68147.1 - 0.004 17.1 4.0 45 4.9 0.1 5.9 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 GAK68147.1 - 0.053 13.5 8.4 32 5.0 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich Repeat Rhomboid PF01694.17 GAK68147.1 - 0.089 12.8 8.8 0.26 11.3 6.1 1.7 1 0 0 1 1 1 0 Rhomboid family Glutaredoxin PF00462.19 GAK68148.1 - 5.3e-14 51.9 0.0 7.6e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 GAK68148.1 - 0.00052 20.2 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 GAK68148.1 - 0.0019 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 GAK68148.1 - 0.0087 16.2 0.1 0.02 15.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 GAK68148.1 - 0.024 14.2 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 GAK68148.1 - 0.033 13.7 0.1 0.069 12.6 0.1 1.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF953 PF06110.6 GAK68148.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 GAK68148.1 - 0.067 12.7 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF4597 PF15366.1 GAK68149.1 - 0.084 12.4 0.9 0.47 10.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Pkinase PF00069.20 GAK68150.1 - 3.4e-68 229.6 0.0 4.3e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68150.1 - 5e-27 94.5 0.0 7e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Slu7 PF11708.3 GAK68151.1 - 2.8e-80 269.5 18.3 2.8e-80 269.5 12.7 2.0 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 GAK68151.1 - 0.15 11.7 1.0 0.27 10.9 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle MAD PF05557.8 GAK68154.1 - 1.1e-40 139.5 45.4 1.4e-39 135.8 31.5 2.1 1 1 0 1 1 1 1 Mitotic checkpoint protein IncA PF04156.9 GAK68154.1 - 0.0015 18.1 62.1 0.024 14.2 7.9 5.9 2 2 2 5 5 5 2 IncA protein DivIC PF04977.10 GAK68154.1 - 0.012 15.0 48.8 1 8.9 0.1 10.2 5 2 6 11 11 11 0 Septum formation initiator DUF972 PF06156.8 GAK68154.1 - 0.014 15.7 36.3 0.27 11.6 1.0 7.4 3 3 2 6 6 6 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 GAK68154.1 - 0.014 14.5 28.1 0.2 10.8 3.5 4.7 4 1 0 4 4 4 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 GAK68154.1 - 0.033 14.4 11.3 0.52 10.5 0.2 5.6 5 2 0 5 5 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 GAK68154.1 - 0.059 12.0 43.4 0.006 15.2 7.1 4.9 4 2 0 4 4 4 0 Spc7 kinetochore protein Shugoshin_N PF07558.6 GAK68154.1 - 0.06 13.0 1.3 21 4.8 0.0 4.4 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region FlaC_arch PF05377.6 GAK68154.1 - 0.12 12.2 9.5 18 5.3 0.1 6.1 6 2 2 8 8 8 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 GAK68154.1 - 0.24 11.1 59.6 0.4 10.4 1.9 6.2 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) HOOK PF05622.7 GAK68154.1 - 0.29 8.8 46.7 0.056 11.2 1.2 4.0 1 1 2 3 3 3 0 HOOK protein Fib_alpha PF08702.5 GAK68154.1 - 0.63 10.1 18.2 2 8.5 1.4 4.7 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family NYD-SP28_assoc PF14775.1 GAK68154.1 - 1.3 8.7 5.9 35 4.1 0.2 4.4 4 0 0 4 4 4 0 Sperm tail C-terminal domain APG6 PF04111.7 GAK68154.1 - 1.6 7.7 55.7 0.0093 15.0 4.4 5.1 2 2 3 5 5 5 0 Autophagy protein Apg6 WD40_alt PF14077.1 GAK68154.1 - 3.6 7.3 18.3 0.37 10.4 0.5 5.4 5 1 1 6 6 6 0 Alternative WD40 repeat motif bZIP_1 PF00170.16 GAK68154.1 - 7.5 6.5 50.7 8.6 6.4 0.1 9.8 6 3 4 10 10 10 0 bZIP transcription factor TBPIP PF07106.8 GAK68154.1 - 9.6 5.7 36.3 0.26 10.8 2.8 5.7 4 2 1 6 6 6 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BTB_2 PF02214.17 GAK68155.1 - 4.8e-06 26.6 0.0 0.065 13.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Prenyltrans PF00432.16 GAK68157.1 - 1.6e-50 168.3 7.7 3.9e-11 42.2 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAK68157.1 - 6e-32 110.3 0.0 1.1e-12 48.3 0.0 3.7 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAK68157.1 - 9.3e-09 35.2 0.0 1e-06 28.6 0.0 3.0 1 1 2 3 3 3 1 Prenyltransferase-like Acetyltransf_1 PF00583.19 GAK68158.1 - 3.2e-10 39.9 0.0 4.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAK68158.1 - 7.2e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAK68158.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAK68158.1 - 0.0017 18.2 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAK68158.1 - 0.034 14.2 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNA_pol_Rpb2_6 PF00562.23 GAK68160.1 - 3.6e-124 414.4 0.3 7e-124 413.4 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAK68160.1 - 2e-66 222.8 0.0 3e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 GAK68160.1 - 3.7e-49 166.7 0.0 1e-48 165.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 GAK68160.1 - 2.5e-27 94.9 0.0 1.2e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 GAK68160.1 - 1.2e-23 82.6 0.6 3.8e-23 81.0 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 GAK68160.1 - 3.7e-22 77.8 0.0 8.9e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 GAK68160.1 - 6e-19 67.7 0.3 1.3e-18 66.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 GAK68160.1 - 0.047 13.5 0.3 0.099 12.4 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain CWC25 PF12542.3 GAK68161.1 - 1.1e-25 89.9 1.3 1.1e-25 89.9 0.9 4.4 3 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 GAK68161.1 - 1.2e-11 44.4 13.1 1.2e-11 44.4 9.1 4.9 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR BTB PF00651.26 GAK68162.1 - 1.1e-08 35.0 0.0 0.00023 21.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain ABC2_membrane PF01061.19 GAK68163.1 - 4.8e-44 150.0 20.5 7.9e-44 149.3 14.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAK68163.1 - 3.6e-23 82.3 0.0 6e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 GAK68163.1 - 4.6e-07 29.1 15.3 4.6e-07 29.1 10.6 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAK68163.1 - 8.2e-05 22.7 0.1 0.35 10.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAK68163.1 - 0.00042 19.7 0.1 0.0015 17.9 0.0 1.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAK68163.1 - 0.0012 18.8 2.2 0.0051 16.8 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_15 PF13175.1 GAK68163.1 - 0.0053 15.8 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAK68163.1 - 0.014 15.5 0.0 0.15 12.1 0.0 2.6 4 0 0 4 4 3 0 AAA domain DUF258 PF03193.11 GAK68163.1 - 0.015 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 GAK68163.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAK68163.1 - 0.046 13.3 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 GAK68163.1 - 0.057 14.2 0.0 0.14 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 GAK68163.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAK68163.1 - 0.09 12.3 0.2 0.21 11.1 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 GAK68163.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAK68163.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF87 PF01935.12 GAK68163.1 - 0.23 11.2 0.3 0.46 10.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Zn_clus PF00172.13 GAK68165.1 - 0.13 12.1 13.6 0.047 13.5 3.9 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 GAK68166.1 - 2.5e-73 246.4 0.0 3e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68166.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK68166.1 - 0.0003 19.8 0.0 0.023 13.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAK68166.1 - 0.045 13.4 1.1 0.065 12.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAK68167.1 - 1.7e-35 122.5 0.0 2.5e-23 82.7 0.0 2.7 3 0 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.18 GAK68167.1 - 9.5e-06 25.5 0.2 0.0094 15.7 0.0 2.8 2 0 0 2 2 2 2 Phosphotransferase enzyme family Hira PF07569.6 GAK68169.1 - 6.6e-54 182.4 0.0 1.5e-53 181.2 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 GAK68169.1 - 2e-41 138.3 23.1 1.1e-09 37.8 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 GAK68169.1 - 4.4e-10 38.8 0.6 1.2e-09 37.4 0.4 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 GAK68169.1 - 0.047 13.3 1.0 2 8.1 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Semialdhyde_dhC PF02774.13 GAK68170.1 - 2.4e-44 151.3 0.0 3.7e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 GAK68170.1 - 7.6e-28 97.2 0.0 1.6e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAK68170.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 GAK68170.1 - 0.018 15.5 0.0 0.05 14.1 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Gp_dh_C PF02800.15 GAK68170.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain CTP_transf_1 PF01148.15 GAK68171.1 - 9.6e-17 61.4 1.6 1.8e-12 47.5 0.6 3.0 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_L35p PF01632.14 GAK68171.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L35 Glyco_hydro_43 PF04616.9 GAK68172.1 - 1.6e-16 60.2 0.0 1.9e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 tRNA_U5-meth_tr PF05958.6 GAK68173.1 - 3.4e-23 81.8 0.0 9.3e-22 77.1 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 GAK68173.1 - 2.6e-11 43.3 0.0 4.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 GAK68173.1 - 4.4e-06 26.3 0.0 8.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 GAK68173.1 - 5.5e-06 26.9 0.0 1.9e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAK68173.1 - 1.8e-05 24.1 0.0 3.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAK68173.1 - 2.3e-05 24.3 0.0 7.4e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAK68173.1 - 0.00044 19.3 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 GAK68173.1 - 0.00057 20.3 0.2 0.0016 18.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 GAK68173.1 - 0.00092 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 GAK68173.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 GAK68173.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 GAK68173.1 - 0.082 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 GAK68173.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family IF4E PF01652.13 GAK68177.1 - 7.5e-46 155.6 0.0 1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ADH_zinc_N PF00107.21 GAK68178.1 - 1.8e-27 95.4 0.0 7e-26 90.3 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAK68178.1 - 2.6e-12 47.7 0.1 1.1e-11 45.6 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAK68178.1 - 6.6e-12 45.1 0.5 1.5e-11 43.9 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CPSase_L_chain PF00289.17 GAK68178.1 - 0.00038 20.5 0.3 0.0047 17.0 0.1 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Peripla_BP_6 PF13458.1 GAK68178.1 - 0.008 15.5 0.1 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein adh_short PF00106.20 GAK68178.1 - 0.014 15.3 0.5 0.026 14.4 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ETF PF01012.16 GAK68178.1 - 0.036 13.7 0.6 0.075 12.7 0.4 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein domain AMP-binding PF00501.23 GAK68179.1 - 3.1e-95 319.0 0.1 3.9e-95 318.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAK68179.1 - 1.1e-24 87.1 1.1 1.2e-22 80.5 0.1 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ACC_epsilon PF13822.1 GAK68180.1 - 3 8.2 6.2 4.3 7.7 0.4 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit OCD_Mu_crystall PF02423.10 GAK68181.1 - 4.9e-27 94.5 2.7 1.3e-26 93.1 1.9 1.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NUT_N PF12881.2 GAK68181.1 - 0.028 13.5 1.5 0.04 13.0 0.4 1.6 2 0 0 2 2 2 0 NUT protein N terminus PI3_PI4_kinase PF00454.22 GAK68182.1 - 5e-32 111.2 0.0 7.4e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 GAK68182.1 - 4.3e-05 22.7 0.3 7.9e-05 21.8 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pik1 PF11522.3 GAK68182.1 - 0.0036 17.0 0.1 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 FAT PF02259.18 GAK68183.1 - 3.7e-70 236.6 7.0 3.7e-70 236.6 4.8 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 GAK68183.1 - 6.6e-22 78.1 0.0 1.8e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 GAK68183.1 - 0.00019 20.7 0.1 0.00056 19.2 0.1 1.8 1 0 0 1 1 1 1 FATC domain Rad4 PF03835.10 GAK68184.1 - 3.4e-28 97.8 0.2 1e-27 96.3 0.2 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 GAK68184.1 - 1.5e-25 88.7 0.1 3.6e-25 87.4 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 GAK68184.1 - 4.4e-14 51.7 0.0 1e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 GAK68184.1 - 2.6e-13 50.0 0.1 2.6e-13 50.0 0.1 2.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 GAK68184.1 - 2.6e-08 34.0 0.1 8.3e-06 25.9 0.0 3.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Transketolase_N PF00456.16 GAK68185.1 - 1.2e-12 47.2 0.1 1.3e-12 47.1 0.1 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DUF726 PF05277.7 GAK68186.1 - 2.7e-114 381.6 1.1 3.8e-114 381.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 GAK68186.1 - 0.0038 17.0 1.2 0.0085 15.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2203 PF09969.4 GAK68186.1 - 1.6 8.9 8.1 0.14 12.4 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) SRP14 PF02290.10 GAK68187.1 - 4.2e-23 81.0 0.1 4.2e-23 81.0 0.1 2.0 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Rota_VP2 PF05087.7 GAK68187.1 - 3.4 5.4 4.9 4.3 5.1 3.4 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein TPR_11 PF13414.1 GAK68189.1 - 4.6e-08 32.5 2.4 0.0049 16.4 0.2 3.0 2 1 1 3 3 3 3 TPR repeat Histone_HNS PF00816.16 GAK68189.1 - 0.0032 17.9 3.5 0.3 11.6 0.5 2.7 3 0 0 3 3 3 2 H-NS histone family TPR_2 PF07719.12 GAK68189.1 - 0.048 13.5 1.4 18 5.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAK68189.1 - 0.072 12.7 0.1 5.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAK68189.1 - 0.19 12.4 9.8 0.18 12.5 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Hepcidin PF06446.7 GAK68189.1 - 2.9 8.3 4.1 1 9.8 0.5 2.0 2 1 0 2 2 2 0 Hepcidin TPR_14 PF13428.1 GAK68189.1 - 6.3 7.7 7.7 0.82 10.4 0.5 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat IPK PF03770.11 GAK68190.1 - 2.8e-38 131.5 0.0 5.6e-37 127.3 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase PH_4 PF15404.1 GAK68191.1 - 3.9e-45 153.6 0.9 6.4e-44 149.6 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain DUF4484 PF14831.1 GAK68191.1 - 0.00014 22.0 1.1 0.00014 22.0 0.8 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4484) Rhodanese PF00581.15 GAK68191.1 - 0.028 14.7 0.0 0.2 12.0 0.0 2.4 3 0 0 3 3 3 0 Rhodanese-like domain Ribosom_S12_S23 PF00164.20 GAK68192.1 - 2.2e-46 156.2 1.2 2.6e-46 156.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ChAPs PF09295.5 GAK68193.1 - 1.9e-157 524.0 0.0 3e-157 523.4 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 GAK68193.1 - 1.5e-07 31.6 0.8 6.1e-05 23.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAK68193.1 - 5.3e-06 25.9 1.9 0.005 16.4 0.1 3.9 3 0 0 3 3 3 1 TPR repeat Apc3 PF12895.2 GAK68193.1 - 0.00013 22.0 1.1 0.36 11.0 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAK68193.1 - 0.0021 18.3 0.3 55 4.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAK68193.1 - 0.011 16.2 10.9 5.1 8.0 0.1 6.5 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAK68193.1 - 0.015 15.1 5.4 7.2 6.8 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat Flagellin_IN PF07196.8 GAK68193.1 - 0.19 11.7 3.8 5.8 6.9 1.1 2.6 2 0 0 2 2 2 0 Flagellin hook IN motif UPF0203 PF05254.7 GAK68195.1 - 7.6e-16 57.7 1.4 2.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) P33MONOX PF15302.1 GAK68195.1 - 0.0013 18.3 1.2 0.0015 18.1 0.8 1.2 1 0 0 1 1 1 1 P33 mono-oxygenase UCR_hinge PF02320.11 GAK68195.1 - 0.0018 18.1 0.2 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 GAK68195.1 - 0.1 12.5 0.7 9.7 6.2 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb COX17 PF05051.8 GAK68195.1 - 0.12 12.3 1.3 0.57 10.2 0.3 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Ndufs5 PF10200.4 GAK68195.1 - 0.13 12.3 0.1 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Herpes_capsid PF06112.6 GAK68195.1 - 2.4 8.1 17.1 0.042 13.8 2.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Arf PF00025.16 GAK68196.1 - 1e-66 223.4 0.0 1.2e-65 220.0 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 GAK68196.1 - 4.5e-10 40.0 0.1 9.4e-08 32.5 0.0 2.5 3 0 0 3 3 2 1 Miro-like protein G-alpha PF00503.15 GAK68196.1 - 3.4e-09 35.8 0.3 9.8e-06 24.4 0.0 3.0 2 1 1 3 3 3 2 G-protein alpha subunit SRPRB PF09439.5 GAK68196.1 - 3.8e-09 35.9 0.0 2.2e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAK68196.1 - 6.5e-08 32.1 0.1 1.6e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 GAK68196.1 - 1.2e-07 31.6 0.1 4.4e-06 26.6 0.0 2.6 3 0 0 3 3 2 1 50S ribosome-binding GTPase PRK PF00485.13 GAK68196.1 - 9.1e-07 28.6 0.0 2.4e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 GAK68196.1 - 2.6e-05 24.5 0.1 0.0024 18.1 0.2 3.0 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 GAK68196.1 - 6.2e-05 22.2 0.0 0.00011 21.3 0.0 1.4 2 0 0 2 2 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAK68196.1 - 8.2e-05 22.1 0.4 0.79 9.1 0.1 3.1 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 GAK68196.1 - 0.0004 20.6 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 GAK68196.1 - 0.00058 20.6 1.3 0.0065 17.2 0.1 2.8 2 2 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 GAK68196.1 - 0.0027 17.1 0.5 0.21 11.0 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 GAK68196.1 - 0.003 17.4 0.4 2.1 8.2 0.1 3.2 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 GAK68196.1 - 0.0031 17.2 0.2 1.6 8.4 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 GAK68196.1 - 0.0052 16.7 0.3 1.1 9.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 GAK68196.1 - 0.014 14.2 0.2 0.11 11.3 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.15 GAK68196.1 - 0.074 12.7 0.3 16 5.1 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_14 PF13173.1 GAK68196.1 - 0.11 12.4 0.0 19 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAK68196.1 - 0.11 11.8 1.1 7.5 5.9 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain CENP-M PF11111.3 GAK68196.1 - 0.15 11.3 0.0 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 Centromere protein M (CENP-M) AAA_29 PF13555.1 GAK68196.1 - 0.3 10.6 2.7 5.6 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IF4E PF01652.13 GAK68197.1 - 1.3e-50 171.1 0.0 1.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Bromo_TP PF07524.8 GAK68198.1 - 8.8e-07 28.5 0.1 1.4e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 GAK68198.1 - 0.008 16.2 7.7 0.017 15.1 1.8 2.7 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Rhodanese PF00581.15 GAK68199.1 - 5.8e-09 36.2 0.0 1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ECH PF00378.15 GAK68200.1 - 9.6e-37 126.4 0.5 2.6e-36 124.9 0.3 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Amidohydro_5 PF13594.1 GAK68202.1 - 0.085 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Amidohydrolase Amidohydro_2 PF04909.9 GAK68202.1 - 0.76 9.2 6.6 0.37 10.3 0.5 2.6 2 1 1 3 3 3 0 Amidohydrolase adh_short_C2 PF13561.1 GAK68203.1 - 3.2e-32 112.2 0.1 3.8e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAK68203.1 - 4.2e-10 39.8 4.0 5.5e-10 39.4 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAK68203.1 - 0.0008 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 GAK68203.1 - 0.0062 15.6 0.1 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 GAK68203.1 - 0.049 13.6 0.1 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding IlvN PF07991.7 GAK68203.1 - 0.052 12.9 0.4 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Eno-Rase_NADH_b PF12242.3 GAK68203.1 - 0.12 12.1 7.9 0.069 12.9 3.3 2.1 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 GAK68203.1 - 0.16 12.0 0.2 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.20 GAK68204.1 - 6.5e-61 205.7 0.0 5.2e-35 120.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68204.1 - 7e-21 74.4 0.0 7.4e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Elong_Iki1 PF10483.4 GAK68204.1 - 1.9e-14 53.7 0.0 7.1e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Elongator subunit Iki1 Kdo PF06293.9 GAK68204.1 - 0.0007 18.7 0.1 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-H2C2_2 PF13465.1 GAK68205.1 - 4.3e-09 36.2 16.6 1.4e-05 25.0 3.6 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAK68205.1 - 1.7e-05 24.9 23.1 0.0017 18.5 1.6 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAK68205.1 - 3.5e-05 23.8 12.1 0.017 15.4 0.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger eIF3_subunit PF08597.5 GAK68206.1 - 8.9e-53 179.3 29.1 1e-52 179.1 20.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit S1FA PF04689.8 GAK68206.1 - 0.19 11.6 4.5 1.3 8.9 0.7 3.0 3 0 0 3 3 3 0 DNA binding protein S1FA SR-25 PF10500.4 GAK68206.1 - 1.2 8.5 16.8 0.15 11.4 5.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein rRNA_processing PF08524.6 GAK68206.1 - 3.8 7.2 16.7 0.28 10.9 6.7 2.1 2 0 0 2 2 2 0 rRNA processing Nop53 PF07767.6 GAK68206.1 - 4.7 6.0 25.0 0.33 9.8 11.3 2.0 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) Response_reg PF00072.19 GAK68207.1 - 2.1e-18 66.3 0.1 6e-18 64.8 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 GAK68207.1 - 2.6e-15 56.0 0.0 5.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAK68207.1 - 0.0001 22.2 1.2 0.00036 20.4 0.8 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain F-box-like PF12937.2 GAK68208.1 - 1.5e-05 24.6 0.2 0.045 13.4 0.0 2.8 2 0 0 2 2 2 2 F-box-like TPR_11 PF13414.1 GAK68208.1 - 0.0005 19.6 0.7 0.0015 18.1 0.5 1.8 1 0 0 1 1 1 1 TPR repeat MIT PF04212.13 GAK68208.1 - 0.0021 17.9 0.2 0.0062 16.3 0.1 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 GAK68208.1 - 0.0027 17.5 0.3 0.0097 15.7 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.28 GAK68208.1 - 0.0028 17.2 2.2 0.29 10.8 0.2 2.4 2 0 0 2 2 2 2 F-box domain TPR_1 PF00515.23 GAK68208.1 - 0.01 15.3 0.2 0.077 12.6 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAK68208.1 - 0.034 14.7 1.1 0.15 12.7 0.7 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Tubulin_3 PF14881.1 GAK68209.1 - 1.4e-32 112.6 0.1 5.7e-32 110.6 0.1 1.9 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 GAK68209.1 - 2e-27 95.5 0.1 4.6e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 GAK68209.1 - 7.4e-05 22.6 0.0 0.51 10.1 0.0 3.4 3 1 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain UBX PF00789.15 GAK68210.1 - 2.5e-06 27.4 0.0 7.5e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 UBX domain zf-C2H2 PF00096.21 GAK68210.1 - 0.023 15.0 0.3 0.045 14.1 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type UBA PF00627.26 GAK68210.1 - 0.07 12.9 0.0 0.41 10.5 0.0 2.4 3 0 0 3 3 3 0 UBA/TS-N domain zf-C2H2_2 PF12756.2 GAK68210.1 - 0.14 12.2 0.1 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ycf1 PF05758.7 GAK68210.1 - 1.1 6.8 4.9 1.2 6.7 3.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF572 PF04502.8 GAK68210.1 - 5 6.2 22.7 3.9 6.6 14.2 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF572) SOBP PF15279.1 GAK68210.1 - 5.2 7.3 5.1 7.3 6.8 3.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CoaE PF01121.15 GAK68211.1 - 4.4e-51 172.8 0.0 5.9e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 GAK68211.1 - 5.3e-05 24.0 0.4 0.00083 20.1 0.3 2.2 1 1 0 1 1 1 1 AAA domain MFS_1 PF07690.11 GAK68212.1 - 7e-33 113.8 42.1 7e-33 113.8 29.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Cytochrom_B561 PF03188.11 GAK68213.1 - 6.7e-09 35.6 8.7 1.5e-08 34.5 6.0 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 GAK68213.1 - 1.2e-06 28.4 1.8 2.4e-06 27.4 1.3 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 GAK68213.1 - 2.8e-06 26.8 3.5 2.8e-06 26.8 2.4 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF4079 PF13301.1 GAK68213.1 - 0.0017 18.3 4.5 0.0017 18.3 3.1 2.8 3 1 1 4 4 4 2 Protein of unknown function (DUF4079) DUF3995 PF13160.1 GAK68213.1 - 0.0029 17.6 1.1 0.0029 17.6 0.8 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3995) PepSY_TM_2 PF13703.1 GAK68213.1 - 0.021 14.9 0.3 0.021 14.9 0.2 3.8 3 1 0 3 3 3 0 PepSY-associated TM helix Polysacc_synt_3 PF13440.1 GAK68213.1 - 0.88 8.9 16.1 0.47 9.8 0.2 2.6 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein SdpI PF13630.1 GAK68213.1 - 9.8 5.9 18.8 2.6 7.8 2.4 3.4 3 1 0 3 3 3 0 SdpI/YhfL protein family AAA_2 PF07724.9 GAK68214.1 - 1.1e-46 158.8 0.0 4.9e-45 153.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAK68214.1 - 3.7e-26 91.8 0.0 5.6e-16 58.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 GAK68214.1 - 1.7e-18 66.3 0.1 8.9e-18 63.9 0.1 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 GAK68214.1 - 5.8e-15 54.9 6.8 3e-07 30.2 0.3 4.2 3 0 0 3 3 3 2 Clp amino terminal domain AAA_5 PF07728.9 GAK68214.1 - 2.4e-14 53.2 0.0 9.7e-09 35.0 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAK68214.1 - 8.8e-12 45.3 10.3 1.7e-05 24.9 0.0 5.2 4 3 0 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.21 GAK68214.1 - 1.7e-09 37.3 0.0 1.2e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 GAK68214.1 - 2.1e-08 34.3 0.2 0.0055 16.8 0.0 4.6 3 2 1 4 4 4 2 AAA domain Zeta_toxin PF06414.7 GAK68214.1 - 2.6e-07 29.9 0.1 0.0012 17.9 0.0 4.0 3 1 1 4 4 4 1 Zeta toxin Mg_chelatase PF01078.16 GAK68214.1 - 0.00012 21.2 0.2 0.56 9.3 0.0 3.4 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAK68214.1 - 0.00035 20.8 0.1 0.9 9.8 0.0 3.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAK68214.1 - 0.00037 19.9 0.0 0.032 13.6 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 GAK68214.1 - 0.00064 19.6 1.5 0.9 9.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain TrwB_AAD_bind PF10412.4 GAK68214.1 - 0.0008 18.1 0.0 1.9 7.0 0.0 3.1 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 GAK68214.1 - 0.00082 20.1 8.2 2.5 8.9 0.0 4.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAK68214.1 - 0.00084 19.0 0.1 0.08 12.7 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain Torsin PF06309.6 GAK68214.1 - 0.0021 17.9 0.0 0.006 16.4 0.0 1.7 1 0 0 1 1 1 1 Torsin AAA_25 PF13481.1 GAK68214.1 - 0.0021 17.4 0.1 1.4 8.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAK68214.1 - 0.0022 18.1 0.1 5 7.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.1 GAK68214.1 - 0.0027 17.6 3.4 0.22 11.4 0.0 3.4 3 1 0 3 3 2 1 AAA domain NACHT PF05729.7 GAK68214.1 - 0.0033 17.1 0.0 2.1 7.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 GAK68214.1 - 0.0055 16.2 0.1 4 7.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 GAK68214.1 - 0.013 14.9 7.8 2.1 7.7 0.1 4.2 3 1 0 5 5 4 0 AAA-like domain DUF258 PF03193.11 GAK68214.1 - 0.015 14.5 0.0 0.83 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 GAK68214.1 - 0.015 14.7 0.1 13 5.2 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 GAK68214.1 - 0.029 14.0 4.3 0.23 11.1 0.0 4.0 4 1 0 5 5 5 0 Archaeal ATPase MobB PF03205.9 GAK68214.1 - 0.031 13.9 0.0 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 GAK68214.1 - 0.032 13.8 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 GAK68214.1 - 0.037 14.3 0.7 13 6.0 0.0 3.4 3 0 0 3 3 3 0 ABC transporter CbiA PF01656.18 GAK68214.1 - 0.038 13.3 0.4 0.87 8.9 0.0 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_3 PF07726.6 GAK68214.1 - 0.041 13.5 0.0 7.6 6.1 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 GAK68214.1 - 0.058 12.9 0.0 14 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain EMP24_GP25L PF01105.19 GAK68214.1 - 0.58 9.8 3.5 0.29 10.8 0.6 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD AAA_13 PF13166.1 GAK68214.1 - 3.4 6.0 10.0 15 3.8 5.9 2.2 2 0 0 2 2 2 0 AAA domain MoCF_biosynth PF00994.19 GAK68215.1 - 2.3e-33 114.6 0.0 3.6e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain His_Phos_2 PF00328.17 GAK68216.1 - 2.3e-29 102.8 0.0 2.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Kinesin PF00225.18 GAK68217.1 - 6.1e-55 186.2 0.0 1.1e-54 185.4 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain Glyco_hydro_3 PF00933.16 GAK68218.1 - 9e-56 189.0 0.0 1.4e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAK68218.1 - 1.9e-39 135.5 0.3 3.4e-39 134.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAK68218.1 - 7.6e-12 45.0 0.0 1.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 GAK68218.1 - 0.057 13.4 0.1 0.46 10.5 0.0 2.6 2 0 0 2 2 2 0 CARDB Acyltransferase PF01553.16 GAK68219.1 - 2.5e-34 117.5 0.0 3.9e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Plant_NMP1 PF06694.6 GAK68219.1 - 0.06 12.2 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) O-antigen_lig PF13425.1 GAK68219.1 - 0.25 11.3 4.5 0.51 10.3 3.2 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BTB PF00651.26 GAK68220.1 - 4.7e-10 39.4 0.0 4.6e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Aldedh PF00171.17 GAK68221.1 - 3.2e-75 253.2 0.0 3.9e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF677 PF05055.7 GAK68221.1 - 0.063 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) gpW PF02831.10 GAK68222.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 gpW CHRD PF07452.7 GAK68222.1 - 0.076 13.6 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 CHRD domain UbiD PF01977.11 GAK68222.1 - 0.15 10.5 0.0 0.47 8.8 0.0 1.8 2 0 0 2 2 2 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF2201_N PF13203.1 GAK68222.1 - 2.6 7.1 5.1 4.3 6.4 3.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Zn_clus PF00172.13 GAK68223.1 - 0.01 15.7 2.2 0.01 15.7 1.5 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3596 PF12167.3 GAK68223.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) ABC_tran PF00005.22 GAK68224.1 - 1.3e-36 125.8 0.0 1.1e-20 74.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAK68224.1 - 2.1e-36 125.7 22.4 3.2e-21 75.9 7.3 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAK68224.1 - 1.9e-10 40.3 0.0 0.00099 18.4 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAK68224.1 - 1.2e-05 24.6 1.5 0.0043 16.5 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 GAK68224.1 - 1.4e-05 25.2 0.6 0.018 15.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAK68224.1 - 6.7e-05 22.9 3.4 0.0053 16.7 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain T2SE PF00437.15 GAK68224.1 - 0.00044 19.2 0.2 0.075 11.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein ArgK PF03308.11 GAK68224.1 - 0.0013 17.6 0.1 0.0024 16.7 0.1 1.3 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 GAK68224.1 - 0.002 18.6 0.3 0.16 12.4 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 GAK68224.1 - 0.0035 16.8 0.5 0.56 9.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 GAK68224.1 - 0.0043 16.4 1.5 0.98 8.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 GAK68224.1 - 0.0078 15.9 0.7 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 GAK68224.1 - 0.008 16.9 0.4 0.067 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 GAK68224.1 - 0.0085 15.9 0.4 1.4 8.8 0.1 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 GAK68224.1 - 0.01 15.6 0.4 0.01 15.6 0.3 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 GAK68224.1 - 0.011 15.2 0.3 0.16 11.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 GAK68224.1 - 0.015 15.4 2.7 7 6.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_10 PF12846.2 GAK68224.1 - 0.026 13.9 1.2 1.1 8.5 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 GAK68224.1 - 0.03 14.6 0.7 0.8 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAK68224.1 - 0.03 13.7 3.1 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 GAK68224.1 - 0.035 12.7 0.9 0.91 8.0 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 GAK68224.1 - 0.037 13.8 0.2 2.8 7.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAK68224.1 - 0.056 13.3 1.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 GAK68224.1 - 0.074 12.2 0.4 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAK68224.1 - 0.14 12.0 1.6 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.12 GAK68224.1 - 0.15 11.5 0.9 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 GAK68224.1 - 0.15 12.3 1.0 1.8 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAK68224.1 - 0.16 11.6 1.2 8.5 6.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.7 GAK68224.1 - 0.24 10.6 1.5 15 4.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein DUF2370 PF10176.4 GAK68225.1 - 6e-77 258.1 0.1 2.4e-76 256.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) RINT1_TIP1 PF04437.8 GAK68226.1 - 1.9e-64 218.0 0.0 3.6e-63 213.8 0.0 2.9 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Cytochrom_B562 PF07361.6 GAK68226.1 - 0.29 11.5 2.1 0.56 10.6 0.0 2.5 3 0 0 3 3 3 0 Cytochrome b562 DUF4013 PF13197.1 GAK68227.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) WD40 PF00400.27 GAK68228.1 - 4.2e-08 32.7 10.3 0.14 12.0 0.1 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 GAK68228.1 - 0.00015 21.8 2.0 13 6.2 0.0 4.5 4 0 0 4 4 4 3 PQQ-like domain PQQ_2 PF13360.1 GAK68228.1 - 0.00018 21.0 0.3 0.029 13.8 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain SH3_9 PF14604.1 GAK68229.1 - 1.3e-14 53.4 0.1 2.5e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAK68229.1 - 3.4e-13 48.7 0.5 6.7e-13 47.8 0.3 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 GAK68229.1 - 1.8e-12 47.4 0.0 4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 GAK68229.1 - 3.2e-11 42.5 0.1 6.3e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 GAK68229.1 - 2.3e-06 27.3 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAK68229.1 - 0.00054 20.0 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 GAK68229.1 - 0.0096 15.9 0.3 0.017 15.1 0.2 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_11 PF15413.1 GAK68229.1 - 0.094 12.9 0.2 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain UPF0160 PF03690.8 GAK68230.1 - 1.1e-122 409.3 0.2 2.4e-122 408.3 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0160) cobW PF02492.14 GAK68230.1 - 6.9e-34 116.8 0.0 1.2e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SNARE_assoc PF09335.6 GAK68230.1 - 3.8e-14 52.9 4.9 8.2e-14 51.8 3.4 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein ArgK PF03308.11 GAK68230.1 - 0.005 15.6 1.5 0.018 13.8 1.1 1.8 1 1 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 GAK68230.1 - 0.011 16.5 0.1 0.26 12.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAK68230.1 - 0.012 15.5 2.2 1.6 8.6 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.1 GAK68230.1 - 0.04 14.2 1.0 0.12 12.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.7 GAK68230.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Arch_ATPase PF01637.13 GAK68230.1 - 0.18 11.4 0.0 0.94 9.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase KAP_NTPase PF07693.9 GAK68230.1 - 0.27 10.1 0.0 0.51 9.2 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain FSH1 PF03959.8 GAK68231.1 - 1.1e-19 70.7 0.0 3.2e-19 69.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.21 GAK68232.1 - 1.8e-47 161.9 0.0 4.2e-47 160.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAK68232.1 - 1.9e-42 145.7 0.0 3.4e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAK68232.1 - 2.4e-29 101.6 0.2 7.5e-29 100.0 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAK68232.1 - 7.2e-19 68.9 0.1 4.3e-18 66.3 0.0 2.3 1 1 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 GAK68232.1 - 5.1e-17 61.9 0.8 9.2e-17 61.1 0.1 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 GAK68232.1 - 1.1e-05 25.1 0.2 0.084 12.6 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAK68232.1 - 0.059 12.3 0.2 0.13 11.2 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Sod_Fe_C PF02777.13 GAK68233.1 - 7.1e-20 70.8 0.1 1.6e-08 34.3 0.1 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Ndc1_Nup PF09531.5 GAK68234.1 - 9.3e-65 219.2 1.3 1.2e-64 218.8 0.9 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup PTE PF02126.13 GAK68234.1 - 0.13 11.2 0.3 0.23 10.4 0.2 1.3 1 0 0 1 1 1 0 Phosphotriesterase family Spore_III_AB PF09548.5 GAK68234.1 - 0.19 11.4 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-RING_2 PF13639.1 GAK68235.1 - 1e-06 28.4 8.3 1e-06 28.4 5.8 1.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAK68235.1 - 9.2e-06 25.2 4.6 9.2e-06 25.2 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK68235.1 - 1.9e-05 24.2 5.0 1.9e-05 24.2 3.5 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAK68235.1 - 0.0008 19.3 11.6 0.0053 16.7 8.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAK68235.1 - 0.0024 17.5 4.5 0.0072 16.0 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 GAK68235.1 - 4.7 7.3 13.8 0.072 13.2 2.5 2.8 3 0 0 3 3 3 0 RING-H2 zinc finger NIF PF03031.13 GAK68237.1 - 1.4e-11 44.3 0.0 2.7e-05 23.8 0.0 3.3 2 1 0 2 2 2 2 NLI interacting factor-like phosphatase CLTH PF10607.4 GAK68238.1 - 1.7e-19 69.9 0.0 3.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAK68238.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 LisH WD40 PF00400.27 GAK68239.1 - 3.3e-35 118.7 11.1 1.3e-08 34.3 0.6 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nha1_C PF08619.5 GAK68239.1 - 0.011 15.0 3.2 0.019 14.2 2.2 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Nucleoporin_N PF08801.6 GAK68239.1 - 0.062 12.0 0.2 5 5.7 0.0 3.0 3 1 0 3 3 3 0 Nup133 N terminal like Autophagy_act_C PF03987.10 GAK68241.1 - 0.0039 17.3 0.3 0.029 14.5 0.2 2.3 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain WD40 PF00400.27 GAK68242.1 - 5e-06 26.2 3.0 0.0055 16.5 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat RF-1 PF00472.15 GAK68243.1 - 8e-17 61.0 1.2 1.1e-16 60.6 0.8 1.2 1 0 0 1 1 1 1 RF-1 domain KH_3 PF13014.1 GAK68243.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 KH domain WD40 PF00400.27 GAK68244.1 - 1.8e-06 27.5 12.6 0.0058 16.4 0.2 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat DNA_pol_A PF00476.15 GAK68245.1 - 1e-89 300.8 0.0 1.8e-89 300.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Exonuc_VII_L PF02601.10 GAK68246.1 - 3 6.9 17.4 4.3 6.4 12.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sdh_cyt PF01127.17 GAK68247.1 - 2.1e-25 88.8 4.1 2.8e-25 88.5 2.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_M16_C PF05193.16 GAK68248.1 - 1.4e-19 70.4 0.0 1.1e-12 47.9 0.0 3.2 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAK68248.1 - 2e-06 27.6 0.0 6.1e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) COX17 PF05051.8 GAK68249.1 - 1.2e-16 60.3 8.2 1.9e-16 59.7 5.7 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 GAK68249.1 - 0.035 13.9 3.8 0.06 13.1 2.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) TP_methylase PF00590.15 GAK68250.1 - 1.4e-31 109.8 0.2 2.9e-31 108.8 0.2 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 GAK68250.1 - 3.5e-11 43.2 0.6 1.3e-09 38.2 0.4 2.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 GAK68250.1 - 2.6e-08 33.0 0.3 8.1e-05 21.8 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 GAK68250.1 - 1.6e-05 23.8 0.1 2.9e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central LEAP-2 PF07359.6 GAK68250.1 - 0.039 13.6 0.1 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Abhydrolase_3 PF07859.8 GAK68253.1 - 6e-19 68.4 0.2 2.1e-16 60.1 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 GAK68253.1 - 3.1e-10 39.2 0.0 2.1e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAK68253.1 - 0.00022 21.0 0.5 0.00045 20.0 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAK68253.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3605 PF12239.3 GAK68254.1 - 6.8e-22 78.0 0.0 1.7e-06 27.9 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) GMC_oxred_N PF00732.14 GAK68255.1 - 2.9e-57 194.0 0.0 3.7e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK68255.1 - 6e-32 110.9 0.4 1.7e-31 109.4 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAK68255.1 - 1.7e-05 23.8 0.9 0.00036 19.5 1.8 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAK68255.1 - 2.1e-05 24.4 1.0 8.2e-05 22.5 0.7 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK68255.1 - 5.1e-05 22.3 0.1 0.00011 21.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAK68255.1 - 0.00043 20.4 2.3 0.013 15.5 0.9 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK68255.1 - 0.0016 17.4 0.1 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAK68255.1 - 0.002 17.2 0.4 0.004 16.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAK68255.1 - 0.026 14.3 2.9 0.043 13.6 1.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK68255.1 - 0.061 11.7 0.4 0.14 10.6 0.3 1.6 1 0 0 1 1 1 0 HI0933-like protein Solute_trans_a PF03619.11 GAK68256.1 - 1e-72 244.7 23.0 1.3e-72 244.3 16.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.6 GAK68256.1 - 3.9 7.3 11.0 0.06 13.2 2.0 2.2 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1713 PF08213.6 GAK68257.1 - 1e-09 37.8 25.2 1e-09 37.8 17.5 1.7 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) TIP49 PF06068.8 GAK68258.1 - 8.4e-181 600.9 0.8 9.9e-181 600.7 0.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 GAK68258.1 - 4.9e-08 33.2 1.4 2e-05 24.7 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAK68258.1 - 7e-07 28.5 2.2 0.00055 19.0 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 GAK68258.1 - 3.4e-06 26.1 0.4 6.3e-06 25.2 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 GAK68258.1 - 0.00043 19.5 1.6 0.0089 15.2 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 GAK68258.1 - 0.00092 19.3 0.2 0.71 10.0 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 GAK68258.1 - 0.0024 17.9 0.0 0.0096 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 GAK68258.1 - 0.0026 17.4 0.8 0.79 9.4 0.1 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAK68258.1 - 0.0085 15.5 1.3 0.013 14.9 0.2 1.8 2 1 0 2 2 2 1 AAA domain Sipho_tail PF05709.6 GAK68258.1 - 0.02 14.0 0.1 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein Zeta_toxin PF06414.7 GAK68258.1 - 0.062 12.3 0.2 0.17 10.9 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 GAK68258.1 - 0.084 12.8 0.1 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 GAK68258.1 - 0.089 12.6 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain COG4 PF08318.7 GAK68259.1 - 9.4e-56 188.9 0.0 1.2e-54 185.2 0.0 2.2 1 1 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.8 GAK68259.1 - 0.057 11.9 2.0 0.23 9.9 0.0 2.5 3 0 0 3 3 3 0 RINT-1 / TIP-1 family Nuf2 PF03800.9 GAK68260.1 - 2.5e-42 144.3 4.6 2.5e-42 144.3 0.0 2.9 2 1 1 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 GAK68260.1 - 0.0014 17.8 4.3 0.0014 17.8 3.0 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein GM_CSF PF01109.12 GAK68260.1 - 0.0023 17.8 1.2 0.0023 17.8 0.9 2.9 2 1 1 3 3 3 1 Granulocyte-macrophage colony-stimulating factor DUF3437 PF11919.3 GAK68260.1 - 0.031 13.9 0.8 0.32 10.7 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) DotA PF11388.3 GAK68260.1 - 0.073 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Baculo_PEP_C PF04513.7 GAK68260.1 - 1.3 8.8 19.3 0.6 9.9 2.2 3.9 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 GAK68260.1 - 5.1 7.1 45.3 0.7 9.9 8.2 4.3 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_G PF04718.10 GAK68260.1 - 5.3 7.7 10.7 0.83 10.3 0.5 4.0 1 1 3 4 4 4 0 Mitochondrial ATP synthase g subunit Methyltransf_16 PF10294.4 GAK68261.1 - 1.6e-18 66.8 0.0 3.4e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 GAK68261.1 - 1.3e-05 25.7 0.0 3.8e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK68261.1 - 1.7e-05 24.5 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK68261.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAK68261.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 GAK68261.1 - 0.029 13.3 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 GAK68261.1 - 0.03 14.7 0.0 0.076 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 GAK68261.1 - 0.042 13.0 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 GAK68261.1 - 0.044 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 GAK68261.1 - 0.095 13.1 0.1 0.85 10.1 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain DUF3466 PF11949.3 GAK68262.1 - 0.0053 15.3 0.0 0.0057 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3466) Glutaredoxin PF00462.19 GAK68264.1 - 7.7e-19 67.4 0.0 3.7e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 GAK68264.1 - 3.6e-15 55.5 0.0 6.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAK68264.1 - 0.0015 18.5 0.1 0.07 13.2 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 GAK68264.1 - 0.0044 16.8 0.1 0.075 12.8 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.6 GAK68264.1 - 0.0072 16.2 0.0 0.14 12.0 0.0 2.5 2 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.1 GAK68264.1 - 0.024 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.10 GAK68264.1 - 0.026 14.4 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein ArsC PF03960.10 GAK68264.1 - 0.075 13.1 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 ArsC family Thioredoxin_2 PF13098.1 GAK68264.1 - 0.13 12.4 0.0 7.1 6.8 0.0 2.9 2 1 0 2 2 2 0 Thioredoxin-like domain RabGAP-TBC PF00566.13 GAK68265.1 - 1.3e-43 148.9 0.0 1.8e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TatD_DNase PF01026.16 GAK68266.1 - 9.8e-06 24.9 0.0 9.8e-06 24.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase LETM1 PF07766.8 GAK68267.1 - 3.4e-95 318.1 2.3 3.4e-95 318.1 1.6 2.4 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 GAK68267.1 - 8.1e-07 29.0 0.3 7.6e-06 25.9 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 GAK68267.1 - 0.00014 21.4 0.4 0.0004 19.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAK68267.1 - 0.00046 19.2 0.6 0.35 10.2 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 GAK68267.1 - 0.009 15.8 0.6 8.4 6.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain DUF1682 PF07946.9 GAK68267.1 - 0.86 8.3 11.8 1.6 7.4 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) WD40 PF00400.27 GAK68268.1 - 5.3e-14 51.4 10.9 0.0072 16.1 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat B3_4 PF03483.12 GAK68269.1 - 3.7e-26 91.6 0.1 6.2e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 GAK68269.1 - 7e-18 64.2 0.0 2.4e-15 56.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 GAK68269.1 - 0.047 12.8 0.0 8.6 5.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) EST1_DNA_bind PF10373.4 GAK68270.1 - 1.5e-32 112.9 0.0 5.8e-32 111.0 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 GAK68270.1 - 3.2e-10 40.0 0.0 1.1e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 Piwi PF02171.12 GAK68271.1 - 8.9e-77 258.0 0.0 1.4e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 GAK68271.1 - 1.1e-16 60.4 0.0 1.8e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 GAK68271.1 - 1.4e-08 33.9 0.0 6.5e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) DUF2461 PF09365.5 GAK68272.1 - 1.3e-29 103.0 0.2 2e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Trypan_PARP PF05887.6 GAK68272.1 - 0.18 11.6 4.2 0.21 11.3 2.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 GAK68272.1 - 0.18 9.8 7.5 0.18 9.8 5.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 GAK68272.1 - 1.2 7.0 11.2 1.4 6.7 7.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 GAK68272.1 - 5.9 6.2 9.1 7.7 5.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4661 PF15576.1 GAK68272.1 - 7.1 6.1 7.4 8.5 5.9 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF2045 PF09741.4 GAK68273.1 - 0.081 12.0 0.0 0.096 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) PAPS_reduct PF01507.14 GAK68274.1 - 6.2e-21 74.9 0.2 5.2e-15 55.6 0.0 3.0 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family PRP3 PF08572.5 GAK68275.1 - 1.8e-61 207.4 0.9 3.6e-61 206.3 0.6 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 GAK68275.1 - 8.8e-29 99.7 0.0 1.5e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) zf-RING_2 PF13639.1 GAK68277.1 - 1e-12 47.6 7.5 2.1e-12 46.6 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAK68277.1 - 1e-11 44.7 5.4 2e-11 43.8 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAK68277.1 - 9.3e-08 31.6 7.5 1.9e-07 30.6 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAK68277.1 - 3e-07 30.1 3.4 7e-07 29.0 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 GAK68277.1 - 9.6e-07 28.3 4.1 1.7e-06 27.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAK68277.1 - 3.7e-06 26.8 6.7 6.8e-06 26.0 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAK68277.1 - 7.1e-06 25.6 5.6 1.3e-05 24.8 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAK68277.1 - 0.013 15.2 2.9 0.032 13.9 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 GAK68277.1 - 0.015 15.3 6.1 0.036 14.1 4.2 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 GAK68277.1 - 0.08 12.9 5.0 0.082 12.8 2.2 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 GAK68277.1 - 0.083 12.4 4.9 0.24 11.0 3.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 GAK68277.1 - 0.13 11.9 5.8 0.26 10.9 4.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 GAK68277.1 - 0.4 10.6 4.3 0.82 9.5 3.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.1 GAK68277.1 - 0.49 10.5 5.0 0.99 9.5 3.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Fes1 PF08609.5 GAK68278.1 - 3.5e-22 78.7 0.9 1.2e-21 76.9 0.6 2.0 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 GAK68278.1 - 1.1e-07 32.0 1.7 0.00024 21.2 0.2 3.0 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 GAK68278.1 - 8.2e-05 22.3 2.1 0.66 10.2 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 GAK68278.1 - 0.0008 19.8 3.5 0.002 18.5 0.0 3.3 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 GAK68278.1 - 0.0071 16.2 0.0 0.16 11.8 0.0 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 GAK68278.1 - 0.0096 14.2 0.1 0.049 11.9 0.1 2.0 1 1 1 2 2 2 1 Adaptin N terminal region Arm PF00514.18 GAK68278.1 - 0.032 14.0 0.1 4.2 7.3 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF448 PF04296.8 GAK68279.1 - 0.00015 21.3 0.3 0.049 13.2 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF448) Herpes_ICP4_N PF03584.10 GAK68279.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Cpn60_TCP1 PF00118.19 GAK68280.1 - 4.3e-144 480.7 0.4 4.9e-144 480.5 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans PF04082.13 GAK68281.1 - 2.5e-28 98.6 0.0 5.8e-28 97.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAK68281.1 - 2.4e-08 33.7 12.7 3.9e-08 33.0 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.16 GAK68282.1 - 1e-116 389.4 0.6 1.8e-116 388.6 0.4 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAK68282.1 - 1.5e-42 145.0 0.1 4.1e-42 143.6 0.1 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 GAK68282.1 - 2.6e-06 26.5 0.0 3.9e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 GAK68282.1 - 5.2e-06 26.3 0.0 1.6e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 GAK68282.1 - 4.6e-05 22.2 0.1 7.6e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 GAK68282.1 - 0.0042 16.6 0.8 0.021 14.3 0.5 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short PF00106.20 GAK68283.1 - 4e-27 95.1 5.6 5.9e-27 94.6 3.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK68283.1 - 1.9e-25 90.0 0.2 2.6e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK68283.1 - 2e-15 56.9 2.9 2.9e-15 56.3 2.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAK68283.1 - 0.00025 20.5 0.6 0.0006 19.3 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAK68283.1 - 0.00026 19.7 0.0 0.00063 18.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox PF00070.22 GAK68283.1 - 0.032 14.6 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_26 PF13659.1 GAK68283.1 - 0.08 12.9 1.6 0.46 10.5 1.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain HTH_Mga PF08280.6 GAK68283.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Cu-oxidase PF00394.17 GAK68284.1 - 1.6e-32 112.6 0.2 4.2e-30 104.7 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAK68284.1 - 1.3e-31 108.7 4.5 1.4e-19 69.9 0.2 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAK68284.1 - 1.6e-29 102.1 11.2 2.6e-29 101.5 2.3 3.3 3 0 0 3 3 3 1 Multicopper oxidase NaeI PF09126.5 GAK68285.1 - 0.094 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI Phosphoesterase PF04185.9 GAK68286.1 - 9.9e-76 255.3 2.5 1.4e-75 254.8 1.7 1.2 1 0 0 1 1 1 1 Phosphoesterase family FliC PF12445.3 GAK68286.1 - 0.0014 18.7 0.9 0.0043 17.1 0.6 1.8 1 0 0 1 1 1 1 Flagellin protein DAO PF01266.19 GAK68287.1 - 1.5e-40 139.2 4.1 1.7e-40 139.0 2.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAK68287.1 - 0.00038 20.5 0.1 0.0024 17.9 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK68287.1 - 0.00042 19.3 0.6 0.054 12.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAK68287.1 - 0.0022 17.7 1.7 0.96 9.2 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Saccharop_dh PF03435.13 GAK68287.1 - 0.0024 16.9 0.1 0.004 16.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase ThiF PF00899.16 GAK68287.1 - 0.0065 16.2 0.2 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.1 GAK68287.1 - 0.0084 16.1 0.2 0.02 14.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAK68287.1 - 0.019 14.8 0.2 0.64 9.8 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4057 PF13266.1 GAK68287.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) ApbA PF02558.11 GAK68287.1 - 0.061 12.7 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 GAK68288.1 - 2e-27 96.1 0.2 8.1e-20 71.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAK68288.1 - 5e-11 42.8 0.0 3.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK68288.1 - 7.3e-08 32.2 0.2 7.8e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 GAK68288.1 - 0.0022 17.7 0.1 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAK68288.1 - 0.026 13.9 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Spt20 PF12090.3 GAK68289.1 - 4.1e-37 127.2 0.0 4.1e-37 127.2 0.0 4.3 4 2 0 4 4 4 1 Spt20 family MIP-T3 PF10243.4 GAK68289.1 - 0.13 10.7 57.7 0.24 9.7 40.0 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NDK PF00334.14 GAK68290.1 - 2.9e-33 114.5 0.0 4e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Cnd2 PF05786.9 GAK68291.1 - 2.2e-144 482.7 4.4 2.3e-143 479.3 0.0 2.1 1 1 0 2 2 2 1 Condensin complex subunit 2 Peptidase_S64 PF08192.6 GAK68291.1 - 7.4 4.7 6.8 1.6 6.9 2.4 1.4 1 1 0 1 1 1 0 Peptidase family S64 Miff PF05644.6 GAK68291.1 - 8.4 5.9 7.3 8.7 5.8 4.3 1.6 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff PBP1_TM PF14812.1 GAK68291.1 - 9.2 6.6 36.4 1 9.7 7.2 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2462 PF09495.5 GAK68292.1 - 8.1e-22 77.7 12.8 8.1e-22 77.7 8.9 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Y_phosphatase2 PF03162.8 GAK68293.1 - 3.2e-58 195.7 0.0 5.4e-58 195.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAK68293.1 - 9.7e-08 32.4 0.0 2.9e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 GAK68293.1 - 0.0003 20.3 0.0 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAK68293.1 - 0.00071 18.9 0.0 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PolyA_pol PF01743.15 GAK68294.1 - 2.2e-21 76.3 0.0 4.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAK68294.1 - 0.00021 20.7 0.1 0.00055 19.4 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A SRP19 PF01922.12 GAK68295.1 - 9.8e-19 67.7 0.0 2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Pkinase PF00069.20 GAK68296.1 - 4.2e-63 212.9 0.0 5.4e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68296.1 - 2.4e-33 115.3 0.0 3.3e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK68296.1 - 1.1e-08 34.4 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAK68296.1 - 0.00088 19.0 0.6 0.0021 17.8 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAK68296.1 - 0.005 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Histidinol_dh PF00815.15 GAK68297.1 - 1.4e-161 537.7 4.4 1.5e-158 527.8 3.0 2.4 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 GAK68297.1 - 9.3e-24 82.8 0.2 1.7e-23 82.0 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 GAK68297.1 - 6e-11 42.4 2.1 7.1e-11 42.2 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Peptidase_S10 PF00450.17 GAK68298.1 - 7e-95 318.6 0.0 1.1e-94 317.9 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 GAK68298.1 - 3e-05 24.0 0.3 0.0001 22.3 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 GAK68299.1 - 2.7e-33 114.7 0.0 4.1e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAK68299.1 - 1.5e-11 44.2 0.5 3.3e-11 43.1 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NPBW PF15180.1 GAK68299.1 - 0.041 13.5 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Neuropeptides B and W AhpC-TSA_2 PF13911.1 GAK68300.1 - 7.7e-13 48.3 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAK68300.1 - 5.6e-08 32.5 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAK68300.1 - 2e-07 30.6 0.0 4.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin Asp PF00026.18 GAK68302.1 - 3.7e-106 354.9 0.1 4.4e-106 354.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAK68302.1 - 6.4e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAK68302.1 - 3.4e-05 24.2 0.1 0.029 14.8 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 GAK68302.1 - 0.00051 19.6 0.0 0.0048 16.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Pkinase PF00069.20 GAK68303.1 - 5.8e-71 238.6 0.0 7.7e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68303.1 - 7.3e-36 123.5 0.0 1e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK68303.1 - 3.5e-05 22.9 0.1 0.00011 21.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAK68303.1 - 0.012 14.7 0.3 0.034 13.2 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Complex1_49kDa PF00346.14 GAK68304.1 - 3e-127 423.2 0.0 4.1e-127 422.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 GAK68304.1 - 0.034 12.9 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Na_Ca_ex PF01699.19 GAK68305.1 - 1.3e-45 154.4 29.0 6.8e-26 90.5 4.8 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein BAF1_ABF1 PF04684.8 GAK68305.1 - 4.1 6.1 13.2 7.7 5.2 9.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.11 GAK68306.1 - 7.8e-30 103.7 32.6 7.8e-30 103.7 22.6 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 GAK68308.1 - 8.8e-07 28.7 8.3 1.6e-06 27.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAK68308.1 - 6.4e-05 21.9 0.1 0.0001 21.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1818 PF08848.6 GAK68308.1 - 0.21 11.6 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) DUF3535 PF12054.3 GAK68310.1 - 4.3e-89 299.1 0.1 4.8e-87 292.4 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) HEAT PF02985.17 GAK68310.1 - 1.3e-09 37.2 14.3 0.14 12.3 0.1 7.9 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 GAK68310.1 - 0.00033 20.8 14.8 2.7 8.3 0.5 6.5 6 2 0 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.2 GAK68310.1 - 0.12 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 GAK68310.1 - 0.15 11.6 0.2 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 GAK68310.1 - 9.7 6.8 22.2 21 5.7 0.2 8.2 10 0 0 10 10 10 0 HEAT-like repeat Ribosomal_L18e PF00828.14 GAK68311.1 - 3.6e-22 79.1 0.0 5.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 MerR_1 PF13411.1 GAK68311.1 - 0.16 11.7 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein Utp21 PF04192.7 GAK68312.1 - 1.2e-52 178.3 0.5 1.8e-52 177.8 0.0 1.5 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 GAK68312.1 - 6.9e-13 47.9 6.7 9.6e-05 22.1 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_2 PF13360.1 GAK68312.1 - 0.00077 18.9 0.9 0.033 13.6 0.1 2.8 2 2 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 GAK68312.1 - 0.038 12.2 0.5 0.27 9.4 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 GAK68312.1 - 0.063 12.7 0.0 5.6 6.5 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cut8_N PF14482.1 GAK68312.1 - 0.96 9.5 5.5 14 5.7 0.6 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain DEAD PF00270.24 GAK68313.1 - 7.4e-43 145.9 0.0 1.5e-42 144.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 GAK68313.1 - 9.2e-21 73.1 0.3 2.5e-20 71.7 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 GAK68313.1 - 1.7e-19 69.4 0.0 3.3e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hist_deacetyl PF00850.14 GAK68314.1 - 9.6e-69 232.0 0.0 1.3e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Zn_clus PF00172.13 GAK68315.1 - 8.6e-06 25.5 10.2 1.5e-05 24.7 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-T PF15511.1 GAK68315.1 - 0.00082 18.7 13.6 0.00082 18.7 9.5 2.1 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T Sporozoite_P67 PF05642.6 GAK68315.1 - 0.044 11.6 12.2 0.07 10.9 8.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YL1 PF05764.8 GAK68315.1 - 0.14 11.6 27.2 0.034 13.7 16.3 1.6 2 0 0 2 2 2 0 YL1 nuclear protein RRN3 PF05327.6 GAK68315.1 - 0.22 9.5 8.0 0.27 9.3 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 GAK68315.1 - 0.26 9.2 25.7 0.39 8.7 17.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 GAK68315.1 - 0.83 7.4 33.9 1.4 6.7 23.5 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 GAK68315.1 - 0.92 7.6 8.2 1.2 7.2 5.7 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2457 PF10446.4 GAK68315.1 - 2.1 6.9 44.2 0.44 9.2 25.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ebola_NP PF05505.7 GAK68315.1 - 2.9 5.8 16.9 3.6 5.5 11.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein WW PF00397.21 GAK68316.1 - 0.013 15.3 1.2 0.033 14.0 0.8 1.7 1 0 0 1 1 1 0 WW domain DUF2076 PF09849.4 GAK68316.1 - 1.9 8.4 25.8 0.023 14.7 7.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_OmpA PF13436.1 GAK68316.1 - 5 6.8 16.3 0.033 13.8 5.4 1.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ETC_C1_NDUFA5 PF04716.9 GAK68317.1 - 2.8e-16 58.7 2.0 5.9e-16 57.7 1.4 1.6 1 1 0 1 1 1 1 ETC complex I subunit conserved region DUF1115 PF06544.7 GAK68318.1 - 3e-07 30.1 0.2 0.0014 18.3 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1115) Slx4 PF09494.5 GAK68318.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Slx4 endonuclease HSP70 PF00012.15 GAK68318.1 - 0.09 10.6 0.5 0.13 10.1 0.4 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF719 PF05334.8 GAK68318.1 - 1.5 8.8 6.7 0.25 11.3 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF719) Sel1 PF08238.7 GAK68319.1 - 2.6e-41 139.1 22.7 4.3e-07 30.3 1.0 8.7 8 0 0 8 8 8 7 Sel1 repeat DAO PF01266.19 GAK68320.1 - 1.7e-45 155.5 0.7 2.6e-45 154.8 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK68320.1 - 5.3e-11 42.0 4.1 1.1e-06 27.7 0.1 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 GAK68320.1 - 4.2e-08 33.2 0.2 7.8e-05 22.6 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAK68320.1 - 7e-06 24.7 0.2 0.017 13.6 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 GAK68320.1 - 1.3e-05 25.1 0.5 7.1e-05 22.7 0.1 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAK68320.1 - 2.4e-05 23.3 0.1 0.064 12.1 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAK68320.1 - 6.4e-05 22.7 0.9 0.14 11.9 0.0 2.5 1 1 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAK68320.1 - 8.6e-05 21.7 0.0 0.0018 17.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 GAK68320.1 - 0.00013 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAK68320.1 - 0.00034 20.9 0.0 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAK68320.1 - 0.0014 18.7 0.1 1.6 8.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAK68320.1 - 0.0018 17.2 0.2 0.015 14.2 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 GAK68320.1 - 0.0054 15.8 0.0 0.0093 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 GAK68320.1 - 0.016 13.8 0.4 0.052 12.1 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase GDI PF00996.13 GAK68320.1 - 0.026 12.8 0.0 2.7 6.2 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_2 PF03446.10 GAK68320.1 - 0.028 14.2 0.0 0.079 12.7 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 GAK68320.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 GAK68320.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain HA2 PF04408.18 GAK68321.1 - 1.1e-28 99.1 0.2 4.6e-28 97.2 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAK68321.1 - 5.4e-28 97.0 0.0 1.2e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAK68321.1 - 4.4e-13 48.8 0.0 1.1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 GAK68321.1 - 5.2e-08 32.8 0.5 1.2e-07 31.6 0.3 1.8 1 1 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 GAK68321.1 - 7.1e-06 25.6 0.1 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAK68321.1 - 0.00031 20.8 0.0 0.00069 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAK68321.1 - 0.00041 19.3 0.2 0.0012 17.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 GAK68321.1 - 0.0036 17.6 0.1 1.2 9.4 0.0 3.4 2 1 1 3 3 3 1 ABC transporter AAA_19 PF13245.1 GAK68321.1 - 0.022 14.5 0.2 0.066 12.9 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 GAK68321.1 - 0.035 13.8 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.1 GAK68321.1 - 0.066 13.1 0.0 0.43 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 GAK68321.1 - 0.072 12.3 0.0 0.2 10.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 GAK68321.1 - 0.12 12.0 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DAGAT PF03982.8 GAK68322.1 - 3.2e-105 351.0 0.0 3.9e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CS PF04969.11 GAK68323.1 - 9.4e-07 29.2 0.0 1.7e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 CS domain Sporozoite_P67 PF05642.6 GAK68323.1 - 0.0037 15.2 0.8 0.0041 15.0 0.5 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen ProQ PF04352.8 GAK68323.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 ProQ/FINO family RskA PF10099.4 GAK68324.1 - 0.11 12.2 2.0 0.097 12.4 1.4 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Shadoo PF14999.1 GAK68324.1 - 0.12 12.2 7.1 0.11 12.3 4.9 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Porin_4 PF13609.1 GAK68324.1 - 0.38 10.2 6.3 0.32 10.4 4.3 1.1 1 0 0 1 1 1 0 Gram-negative porin K_channel_TID PF07941.6 GAK68324.1 - 0.89 9.8 10.5 1.3 9.2 7.3 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PepSY_2 PF13670.1 GAK68324.1 - 7.9 6.4 10.5 10 6.0 7.3 1.3 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain MFS_1 PF07690.11 GAK68325.1 - 4.3e-45 153.9 46.7 5.2e-43 147.1 34.0 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAK68325.1 - 2.8e-21 75.3 33.8 6.3e-21 74.2 23.3 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAK68325.1 - 2.7e-11 42.7 35.8 9e-11 40.9 7.6 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter DUF2370 PF10176.4 GAK68325.1 - 0.14 11.4 2.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) MFS_1_like PF12832.2 GAK68325.1 - 0.29 10.9 6.5 0.4 10.4 0.3 3.4 3 0 0 3 3 3 0 MFS_1 like family DUF3530 PF12048.3 GAK68325.1 - 2.7 6.9 5.9 0.11 11.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) DUF1049 PF06305.6 GAK68326.1 - 0.053 13.0 1.4 0.085 12.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) XPG_N PF00752.12 GAK68327.1 - 1.9e-29 101.8 0.0 3.9e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 GAK68327.1 - 2.5e-25 88.3 0.0 7.4e-25 86.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region API5 PF05918.6 GAK68327.1 - 2 6.8 8.3 3.1 6.1 5.7 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Y_phosphatase2 PF03162.8 GAK68328.1 - 2.7e-49 166.6 0.0 3.1e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAK68328.1 - 3.4e-05 24.1 0.0 0.00048 20.4 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 GAK68328.1 - 0.0054 16.3 0.0 0.009 15.6 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAK68328.1 - 0.046 13.0 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Voltage_CLC PF00654.15 GAK68329.1 - 1.2e-93 313.9 26.1 1.2e-93 313.9 18.1 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel DASH_Hsk3 PF08227.6 GAK68329.1 - 1.4e-11 44.4 0.8 1.4e-11 44.4 0.5 2.3 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like CBS PF00571.23 GAK68329.1 - 0.00017 21.3 0.0 0.00086 19.0 0.0 2.1 2 0 0 2 2 2 1 CBS domain Alk_phosphatase PF00245.15 GAK68330.1 - 5.3e-91 305.4 0.1 6.7e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase HMGL-like PF00682.14 GAK68331.1 - 2.7e-71 239.9 0.4 4.7e-71 239.2 0.3 1.4 1 0 0 1 1 1 1 HMGL-like OTU PF02338.14 GAK68332.1 - 1.1e-18 67.9 0.0 2.7e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 GAK68332.1 - 0.001 18.4 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain T2SM PF04612.7 GAK68332.1 - 0.016 15.0 0.4 1.2 8.9 0.8 2.5 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M TPR_20 PF14561.1 GAK68332.1 - 0.92 9.6 6.8 0.93 9.6 0.9 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat PAP2 PF01569.16 GAK68333.1 - 3.2e-16 59.1 3.6 5.8e-16 58.3 2.5 1.4 1 0 0 1 1 1 1 PAP2 superfamily dCMP_cyt_deam_1 PF00383.17 GAK68333.1 - 9.7e-11 41.2 0.0 1.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 GAK68333.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain EamA PF00892.15 GAK68334.1 - 6.9e-21 74.5 23.4 8e-12 45.3 2.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 GAK68334.1 - 0.0003 20.9 4.7 0.0003 20.9 3.3 3.1 2 1 0 3 3 3 2 Multidrug resistance efflux transporter MLANA PF14991.1 GAK68334.1 - 0.067 13.2 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein melan-A TPT PF03151.11 GAK68334.1 - 7.1 6.2 20.1 0.34 10.5 2.0 2.6 2 2 0 2 2 2 0 Triose-phosphate Transporter family DNA_methylase PF00145.12 GAK68335.1 - 3.2e-12 46.2 0.0 7.7e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase AIF-MLS PF14962.1 GAK68335.1 - 0.01 15.4 1.1 0.018 14.7 0.0 1.9 2 0 0 2 2 2 0 Mitochondria Localisation Sequence SHQ1 PF04925.10 GAK68336.1 - 7.3e-36 123.3 0.0 1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 SHQ1 protein WAPL PF07814.8 GAK68337.1 - 9e-09 34.5 1.8 3.5e-08 32.5 0.0 2.6 3 0 0 3 3 3 1 Wings apart-like protein regulation of heterochromatin BIR PF00653.16 GAK68338.1 - 5e-25 87.7 0.2 2.7e-20 72.5 0.3 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Meth_synt_2 PF01717.13 GAK68339.1 - 6.6e-24 84.4 0.0 9.9e-24 83.8 0.0 1.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAK68339.1 - 7.2e-08 32.0 0.0 0.031 13.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain adh_short PF00106.20 GAK68340.1 - 1.2e-19 70.8 2.1 2e-18 66.8 1.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAK68340.1 - 1.6e-18 67.4 0.6 6.5e-17 62.1 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAK68340.1 - 9.3e-09 35.1 1.2 1.4e-07 31.3 0.1 2.2 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 GAK68340.1 - 0.026 14.6 0.1 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAK68340.1 - 0.057 13.4 0.5 2.1 8.2 0.2 2.3 2 1 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAK68340.1 - 0.22 11.3 1.1 0.46 10.3 0.8 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_39 PF01229.12 GAK68341.1 - 2.9e-05 22.6 0.0 4.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Astacin PF01400.19 GAK68342.1 - 7.4e-10 38.5 0.2 1.7e-09 37.3 0.1 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 GAK68342.1 - 3.2e-06 26.9 1.6 0.00019 21.1 1.1 2.4 1 1 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 GAK68342.1 - 0.00072 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 GAK68342.1 - 0.038 13.5 0.1 0.072 12.6 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Alginate_lyase PF05426.7 GAK68343.1 - 3.8e-09 36.3 0.0 8.7e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Alginate lyase RTA1 PF04479.8 GAK68344.1 - 6.6e-35 120.6 9.5 1e-34 120.0 6.6 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4345 PF14248.1 GAK68345.1 - 3e-19 68.6 9.1 3.2e-19 68.5 6.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) DUF2583 PF10762.4 GAK68345.1 - 0.035 14.2 1.4 0.083 13.0 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) DUF2065 PF09838.4 GAK68345.1 - 0.047 13.4 2.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Ribosomal_L23 PF00276.15 GAK68346.1 - 9.3e-08 31.9 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 SKI PF01202.17 GAK68347.1 - 4.2e-12 46.2 0.0 5.1e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.1 GAK68347.1 - 5.2e-08 32.8 0.4 5.8e-07 29.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK68347.1 - 1.7e-07 32.0 0.0 5.4e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAK68347.1 - 6.8e-06 26.4 0.2 0.00021 21.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAK68347.1 - 0.0003 20.8 0.1 0.00058 19.8 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin2 PF13189.1 GAK68347.1 - 0.00053 19.9 0.0 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_22 PF13401.1 GAK68347.1 - 0.0014 18.8 0.8 0.2 11.7 0.1 2.8 1 1 1 3 3 3 1 AAA domain APS_kinase PF01583.15 GAK68347.1 - 0.0098 15.5 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF2075 PF09848.4 GAK68347.1 - 0.02 13.8 0.0 0.061 12.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 GAK68347.1 - 0.023 14.2 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.15 GAK68347.1 - 0.029 13.7 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase Herpes_Helicase PF02689.9 GAK68347.1 - 0.033 11.9 0.0 0.084 10.6 0.0 1.6 2 0 0 2 2 2 0 Helicase ABC_tran PF00005.22 GAK68347.1 - 0.034 14.4 0.1 0.059 13.6 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 GAK68347.1 - 0.042 13.8 1.1 0.4 10.6 0.3 2.4 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAK68347.1 - 0.067 12.6 0.9 0.067 12.6 0.6 2.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 GAK68347.1 - 0.083 13.0 0.2 0.22 11.7 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAK68347.1 - 0.14 11.5 2.2 0.35 10.2 0.2 2.3 1 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAK68347.1 - 0.19 11.1 1.2 2.7 7.3 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain NIF PF03031.13 GAK68349.1 - 1.6e-48 164.4 0.0 3.5e-48 163.2 0.0 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Sec1 PF00995.18 GAK68350.1 - 1.5e-161 538.8 0.0 2.3e-161 538.2 0.0 1.2 1 0 0 1 1 1 1 Sec1 family PAT1 PF09770.4 GAK68351.1 - 8.6e-73 245.9 33.1 1e-72 245.6 23.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SUZ PF12752.2 GAK68351.1 - 1.4 9.5 7.3 12 6.5 0.2 2.9 1 1 1 2 2 2 0 SUZ domain GTP_EFTU PF00009.22 GAK68352.1 - 1e-24 86.9 0.0 1.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 GAK68352.1 - 7.1e-09 35.6 0.4 3.4e-08 33.4 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 GAK68352.1 - 1.3e-08 34.8 0.1 2.9e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.1 GAK68352.1 - 4.1e-06 26.3 0.5 1.1e-05 24.9 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 HhH-GPD PF00730.20 GAK68353.1 - 1.1e-18 67.5 0.0 2.4e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAK68353.1 - 1.3e-08 34.0 0.0 4.9e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 GAK68353.1 - 0.038 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain OMPdecase PF00215.19 GAK68354.1 - 1.6e-75 253.4 0.0 2e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mit_ribos_Mrp51 PF11709.3 GAK68355.1 - 8.8e-14 51.4 0.1 2.1e-12 46.9 0.1 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF4526 PF15029.1 GAK68355.1 - 0.2 11.1 0.0 8.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) Cyclin PF08613.6 GAK68356.1 - 8.9e-10 39.1 0.4 2.6e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 Cyclin zf-NADH-PPase PF09297.6 GAK68359.1 - 0.0036 16.7 0.8 0.0094 15.4 0.5 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 GAK68359.1 - 0.04 13.7 4.6 0.17 11.7 3.2 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Rubredoxin PF00301.15 GAK68359.1 - 0.21 11.4 3.4 2.5 8.0 0.2 2.8 2 0 0 2 2 2 0 Rubredoxin DZR PF12773.2 GAK68359.1 - 0.35 10.7 3.3 1.1 9.1 2.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 GAK68359.1 - 0.74 9.5 4.5 4.6 6.9 0.2 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS CM_2 PF01817.16 GAK68360.1 - 6.5e-08 32.5 0.1 2.1e-05 24.4 0.0 3.5 2 1 1 3 3 3 2 Chorismate mutase type II NIF PF03031.13 GAK68361.1 - 1.2e-19 70.4 0.0 1.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 GAK68361.1 - 0.00012 21.3 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CO_deh_flav_C PF03450.12 GAK68361.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.5 1 1 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Kinesin PF00225.18 GAK68363.1 - 8.2e-113 376.4 0.0 8.2e-113 376.4 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain YqeY PF09424.5 GAK68363.1 - 8e-14 51.7 4.2 8e-14 51.7 2.9 3.5 4 0 0 4 4 4 1 Yqey-like protein DUF465 PF04325.8 GAK68363.1 - 5.9e-12 45.1 3.1 5.9e-12 45.1 2.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF465) Filament PF00038.16 GAK68363.1 - 0.0043 16.5 44.0 0.0043 16.5 30.5 4.3 3 1 1 4 4 4 1 Intermediate filament protein GTP_EFTU PF00009.22 GAK68364.1 - 1.2e-21 77.0 0.0 2e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 GAK68364.1 - 1.2e-10 41.3 4.2 2.2e-10 40.5 2.9 1.4 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 GAK68364.1 - 0.00066 19.6 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF1296 PF06972.6 GAK68364.1 - 0.022 14.7 0.2 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Septin PF00735.13 GAK68364.1 - 0.24 10.3 0.0 0.39 9.7 0.0 1.3 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 GAK68364.1 - 9.3 4.8 6.8 0.4 9.3 0.1 2.0 2 0 0 2 2 2 0 G-protein alpha subunit DUF4202 PF13875.1 GAK68365.1 - 8.1e-63 211.4 0.1 2e-62 210.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF1754 PF08555.5 GAK68365.1 - 1.6e-16 60.6 11.0 1.6e-16 60.6 7.6 2.4 3 0 0 3 3 3 1 Eukaryotic family of unknown function (DUF1754) Methyltransf_23 PF13489.1 GAK68365.1 - 6.2e-16 58.5 0.0 1.2e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK68365.1 - 7.6e-14 51.9 0.0 5e-13 49.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK68365.1 - 1.6e-10 41.3 0.0 7.4e-10 39.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAK68365.1 - 2.6e-10 40.1 0.0 4.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAK68365.1 - 3.4e-10 40.2 0.0 1.5e-09 38.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK68365.1 - 1e-09 38.9 0.0 3.4e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAK68365.1 - 1.3e-07 31.6 0.2 1.2e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 GAK68365.1 - 9.3e-05 23.2 0.0 0.00055 20.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAK68365.1 - 0.00045 19.6 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain ADK PF00406.17 GAK68366.1 - 5.6e-47 159.3 0.0 7.8e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 GAK68366.1 - 5.4e-09 36.4 0.0 9.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAK68366.1 - 1.2e-06 28.4 0.0 3.1e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAK68366.1 - 2.4e-06 28.3 0.0 5.3e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 GAK68366.1 - 5.6e-05 22.5 0.2 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 GAK68366.1 - 0.0093 15.0 0.0 0.017 14.1 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin Dynamitin PF04912.9 GAK68367.1 - 3.9e-34 118.0 11.1 2.9e-19 69.1 0.2 2.5 3 0 0 3 3 3 2 Dynamitin Fib_alpha PF08702.5 GAK68367.1 - 0.007 16.4 1.0 0.021 14.9 0.7 1.9 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Matrilin_ccoil PF10393.4 GAK68367.1 - 0.0085 15.4 1.5 0.92 8.9 0.1 3.6 2 1 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin PilJ PF13675.1 GAK68367.1 - 0.094 13.0 19.6 0.11 12.8 1.2 4.4 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term LPP20 PF02169.11 GAK68367.1 - 0.71 10.0 5.8 1.2 9.2 0.4 2.8 2 0 0 2 2 2 0 LPP20 lipoprotein Baculo_PEP_C PF04513.7 GAK68367.1 - 0.85 9.4 6.7 0.96 9.2 0.9 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 GAK68367.1 - 0.98 9.6 6.1 0.92 9.7 0.6 3.0 2 1 0 2 2 2 0 Syntaxin Transp_cyt_pur PF02133.10 GAK68368.1 - 1.6e-31 109.3 26.6 2.9e-31 108.5 18.4 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OST3_OST6 PF04756.8 GAK68369.1 - 1.7e-20 73.2 4.1 2.6e-20 72.5 2.9 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 GAK68369.1 - 3.5e-05 23.4 0.1 7.3e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin VIT1 PF01988.14 GAK68369.1 - 9.6e-05 21.9 3.3 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 2 VIT family HlyIII PF03006.15 GAK68369.1 - 0.0023 17.3 6.3 0.017 14.5 0.7 2.4 2 0 0 2 2 2 2 Haemolysin-III related DSBA PF01323.15 GAK68369.1 - 0.22 11.0 1.8 0.7 9.4 0.1 2.4 3 0 0 3 3 3 0 DSBA-like thioredoxin domain WD40 PF00400.27 GAK68370.1 - 4.5e-54 178.5 21.2 1.2e-08 34.4 0.1 8.4 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 GAK68370.1 - 1.4e-07 30.0 4.3 0.053 11.6 0.1 3.7 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Cse1 PF08506.5 GAK68371.1 - 7.8e-135 449.1 0.5 6.3e-133 442.9 0.3 2.3 2 0 0 2 2 2 2 Cse1 CAS_CSE1 PF03378.10 GAK68371.1 - 8.6e-117 390.0 0.0 2.5e-116 388.5 0.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 GAK68371.1 - 3.6e-11 42.8 3.9 8.3e-11 41.6 0.6 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAK68371.1 - 0.0018 18.1 4.4 0.0054 16.6 0.0 4.0 5 0 0 5 5 5 1 Exportin 1-like protein HEAT PF02985.17 GAK68371.1 - 0.025 14.6 0.3 25 5.3 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat NDUFA12 PF05071.11 GAK68372.1 - 7e-10 39.3 0.2 1.6e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF1421 PF07223.6 GAK68372.1 - 0.042 13.6 12.9 0.055 13.2 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) TPR_11 PF13414.1 GAK68373.1 - 5.1e-15 54.8 11.8 1.4e-12 47.0 2.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAK68373.1 - 3.7e-08 32.6 6.6 0.014 15.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAK68373.1 - 3.9e-07 29.4 6.9 0.0032 17.2 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAK68373.1 - 1.5e-05 25.2 11.6 0.00033 20.9 1.2 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAK68373.1 - 0.00055 20.3 9.5 0.094 13.4 0.1 3.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK68373.1 - 0.0023 18.5 16.3 0.0073 16.9 1.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAK68373.1 - 0.0035 17.0 2.1 0.15 11.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAK68373.1 - 0.011 15.8 5.6 0.03 14.4 3.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.7 GAK68373.1 - 0.068 12.7 1.6 2.3 7.7 0.0 2.2 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Alkyl_sulf_dimr PF14863.1 GAK68373.1 - 0.53 10.5 3.0 8.8 6.5 0.3 2.4 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_12 PF13424.1 GAK68373.1 - 1.1 9.2 11.3 0.55 10.2 0.1 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Surfac_D-trimer PF09006.6 GAK68374.1 - 0.047 13.4 1.6 4.2 7.1 0.1 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF836 PF05768.9 GAK68375.1 - 3.7e-12 46.3 0.1 4.6e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.16 GAK68375.1 - 0.0077 15.9 0.0 0.0096 15.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Robl_LC7 PF03259.12 GAK68376.1 - 2.7e-05 23.6 0.0 5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Roadblock/LC7 domain DLIC PF05783.6 GAK68376.1 - 0.028 13.0 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Zn_clus PF00172.13 GAK68377.1 - 0.019 14.8 10.8 0.21 11.5 7.5 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 GAK68378.1 - 4.9e-59 199.8 3.0 1.2e-57 195.2 0.2 2.8 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.15 GAK68378.1 - 5e-20 72.6 0.0 2.8e-19 70.2 0.0 2.4 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAK68378.1 - 8.6e-19 67.5 3.8 2.5e-09 37.2 0.5 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.17 GAK68378.1 - 3.7e-13 49.3 0.9 1.2e-12 47.7 0.7 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HA2 PF04408.18 GAK68379.1 - 1.6e-17 63.3 1.6 1.9e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAK68379.1 - 2e-16 59.5 0.1 4.2e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAK68379.1 - 3e-10 39.8 0.0 1.5e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 GAK68379.1 - 5.5e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 GAK68379.1 - 0.00011 22.3 0.0 0.00034 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAK68379.1 - 0.0043 16.1 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 GAK68379.1 - 0.01 14.7 0.0 0.073 11.9 0.0 2.3 2 1 1 3 3 3 0 Type II/IV secretion system protein DUF494 PF04361.8 GAK68379.1 - 0.086 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) PhoH PF02562.11 GAK68379.1 - 0.16 11.2 0.2 0.44 9.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Astacin PF01400.19 GAK68380.1 - 9e-08 31.7 0.0 2.6e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 GAK68380.1 - 0.054 13.2 3.8 0.32 10.7 2.6 2.1 1 1 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.8 GAK68380.1 - 0.066 12.8 0.0 0.24 10.9 0.0 2.0 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A WW PF00397.21 GAK68381.1 - 5e-11 42.2 0.4 1.1e-10 41.1 0.3 1.7 1 0 0 1 1 1 1 WW domain CPSF_A PF03178.10 GAK68382.1 - 4.6e-53 180.3 0.0 1.5e-52 178.6 0.0 1.8 1 1 0 1 1 1 1 CPSF A subunit region Ribosomal_S26e PF01283.14 GAK68383.1 - 2.1e-46 156.8 4.6 3.6e-46 156.0 3.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S26e LRR_6 PF13516.1 GAK68385.1 - 9.6e-07 28.2 0.3 41 4.6 0.1 7.0 7 0 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.1 GAK68385.1 - 0.00027 20.6 0.1 0.0077 15.9 0.0 3.1 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 GAK68385.1 - 0.002 17.7 0.1 2 8.1 0.1 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) AMP-binding PF00501.23 GAK68386.1 - 5.5e-77 258.9 0.0 7.6e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAK68386.1 - 2.9e-62 209.8 0.1 7e-58 195.4 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 GAK68386.1 - 1.3e-35 122.7 7.3 2.5e-32 112.0 1.9 3.3 3 1 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 GAK68386.1 - 3.6e-22 78.8 3.4 5.2e-18 65.3 1.7 2.7 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 GAK68386.1 - 1.4e-21 77.0 0.1 7.9e-11 41.8 0.0 3.1 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAK68386.1 - 5.5e-20 72.1 0.2 9.7e-19 68.0 0.3 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 GAK68386.1 - 2.5e-10 39.5 0.2 9e-06 24.5 0.0 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAK68386.1 - 1.3e-09 38.3 2.9 0.00046 20.2 1.6 4.3 3 1 0 3 3 3 2 NADH(P)-binding PP-binding PF00550.20 GAK68386.1 - 5e-08 33.0 0.0 1.4e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAK68386.1 - 3.1e-07 31.2 0.3 1.7e-06 28.8 0.1 2.5 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 GAK68386.1 - 1.4e-06 27.4 1.9 8.2e-05 21.6 0.1 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 GAK68386.1 - 0.0013 17.8 0.2 0.004 16.2 0.1 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 GAK68386.1 - 0.04 13.5 2.8 0.33 10.5 1.9 2.3 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_3 PF03447.11 GAK68386.1 - 0.058 13.7 2.6 7.1 7.0 0.0 3.5 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.8 GAK68386.1 - 0.17 11.1 1.3 7.2 5.7 0.3 3.3 4 0 0 4 4 4 0 NmrA-like family HRXXH PF13933.1 GAK68387.1 - 2.5e-32 112.2 0.6 2.5e-32 112.2 0.4 1.5 2 0 0 2 2 2 1 Putative peptidase family FH2 PF02181.18 GAK68388.1 - 2.9e-65 220.5 5.3 2.9e-65 220.5 3.6 2.7 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 GAK68388.1 - 1.3e-44 151.9 0.0 1.2e-43 148.8 0.0 2.3 1 1 1 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 GAK68388.1 - 2.9e-44 150.6 0.1 2.4e-43 147.6 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain IncA PF04156.9 GAK68388.1 - 4.5 6.8 20.1 0.13 11.8 6.3 2.9 2 1 0 2 2 2 0 IncA protein CorA PF01544.13 GAK68388.1 - 5.6 5.8 11.3 1 8.3 0.4 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CorA PF01544.13 GAK68389.1 - 7.8e-11 41.5 0.3 1.1e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UreD PF01774.12 GAK68390.1 - 8.5e-57 192.0 0.0 1.3e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 UreD urease accessory protein EI24 PF07264.6 GAK68390.1 - 0.0046 16.4 2.7 0.0087 15.5 1.9 1.4 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) UcrQ PF02939.11 GAK68391.1 - 2.8e-24 84.7 1.8 3.4e-24 84.4 1.3 1.1 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 GAK68391.1 - 0.035 14.2 0.2 0.064 13.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2741) Fe-ADH PF00465.14 GAK68392.1 - 1.1e-70 238.0 0.1 1.5e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAK68392.1 - 2.1e-17 63.2 0.0 9.5e-10 38.1 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Transposase_24 PF03004.9 GAK68392.1 - 0.017 15.0 0.4 0.11 12.3 0.3 1.9 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DCX PF03607.12 GAK68392.1 - 0.034 13.7 0.0 6.2 6.4 0.0 3.0 2 1 1 3 3 3 0 Doublecortin AAA_16 PF13191.1 GAK68392.1 - 0.077 12.9 0.1 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain DUF2296 PF10058.4 GAK68393.1 - 2.3e-24 84.8 0.2 3.7e-24 84.2 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Mu-like_Com PF10122.4 GAK68393.1 - 0.23 10.5 1.2 0.38 9.8 0.1 1.9 2 0 0 2 2 2 0 Mu-like prophage protein Com LIM PF00412.17 GAK68394.1 - 5.6e-28 96.7 35.5 1.1e-12 47.8 2.0 5.1 4 1 0 4 4 4 4 LIM domain tRNA-synt_2 PF00152.15 GAK68395.1 - 3.6e-103 344.8 0.0 1.9e-51 174.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAK68395.1 - 1.2e-05 25.0 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 GAK68395.1 - 0.00082 18.9 0.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 GAK68395.1 - 0.022 13.9 0.0 1.2 8.2 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) SNF5 PF04855.7 GAK68396.1 - 2.3e-67 227.0 1.5 9.4e-65 218.4 0.1 2.2 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 SBDS PF01172.13 GAK68397.1 - 8.8e-15 54.2 0.1 1.1e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Clp1 PF06807.9 GAK68401.1 - 3.8e-20 72.4 0.0 5.4e-19 68.7 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 DUF3435 PF11917.3 GAK68401.1 - 0.0021 16.8 2.3 0.028 13.1 1.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) MMR_HSR1 PF01926.18 GAK68401.1 - 0.025 14.5 0.0 12 5.8 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase MobB PF03205.9 GAK68401.1 - 0.025 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 GAK68401.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAK68401.1 - 0.41 11.1 0.0 0.89 10.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 GAK68401.1 - 0.44 10.0 0.0 1.5 8.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TOM13 PF08219.6 GAK68403.1 - 3.5e-10 39.4 0.9 7.2e-10 38.4 0.7 1.7 1 1 0 1 1 1 1 Outer membrane protein TOM13 DUF4462 PF14692.1 GAK68403.1 - 0.057 12.6 0.8 0.11 11.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) E1-E2_ATPase PF00122.15 GAK68404.1 - 2.3e-25 88.9 0.0 2e-24 85.9 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 GAK68404.1 - 5.7e-22 78.8 0.0 1.6e-21 77.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAK68404.1 - 1e-16 61.9 0.2 2e-14 54.5 0.0 3.9 3 2 1 4 4 4 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK68404.1 - 6.4e-08 32.4 0.0 2.1e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit P5-ATPase PF12409.3 GAK68404.1 - 1e-05 25.3 0.3 4e-05 23.4 0.0 2.2 3 0 0 3 3 3 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.21 GAK68404.1 - 2.9e-05 23.4 0.0 8.8e-05 21.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Tautomerase PF01361.16 GAK68404.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Tautomerase enzyme Docking PF08990.6 GAK68405.1 - 0.14 11.4 0.4 0.26 10.5 0.3 1.4 1 0 0 1 1 1 0 Erythronolide synthase docking DUF1712 PF08217.6 GAK68406.1 - 3e-08 32.3 0.0 4.5e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Coatomer_WDAD PF04053.9 GAK68407.1 - 8.7e-139 463.1 0.0 1.5e-138 462.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 GAK68407.1 - 6.4e-81 272.0 0.0 9.7e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 GAK68407.1 - 5.4e-55 181.4 8.1 3.1e-11 42.7 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Clathrin PF00637.15 GAK68407.1 - 0.019 14.5 0.1 0.097 12.2 0.0 2.2 3 0 0 3 3 3 0 Region in Clathrin and VPS Nup160 PF11715.3 GAK68407.1 - 0.022 12.9 5.9 0.27 9.3 0.0 3.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 p31comet PF06581.7 GAK68408.1 - 0.029 13.2 2.0 0.1 11.4 0.5 2.4 3 0 0 3 3 3 0 Mad1 and Cdc20-bound-Mad2 binding E1-E2_ATPase PF00122.15 GAK68409.1 - 9.5e-53 178.5 3.8 2e-52 177.5 2.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAK68409.1 - 1.6e-40 138.5 2.7 1.6e-40 138.5 1.9 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAK68409.1 - 5.2e-30 105.4 0.0 4.3e-29 102.4 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAK68409.1 - 2.8e-16 59.2 0.0 5.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAK68409.1 - 2.7e-14 53.7 0.2 9.6e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAK68409.1 - 1.3e-12 47.0 0.2 3.2e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAK68409.1 - 0.00086 18.9 0.8 0.0016 18.0 0.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_C32 PF05411.7 GAK68409.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase DUF2231 PF09990.4 GAK68409.1 - 1.1 9.5 7.9 0.48 10.7 0.3 3.6 4 0 0 4 4 4 0 Predicted membrane protein (DUF2231) SUR7 PF06687.7 GAK68409.1 - 4.7 6.7 10.8 0.5 9.8 0.4 3.1 3 0 0 3 3 3 0 SUR7/PalI family Orthoreo_P10 PF07204.6 GAK68410.1 - 0.0052 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.1 GAK68410.1 - 0.014 15.7 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 GAK68410.1 - 3.3 7.8 10.8 84 3.2 7.5 2.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Arginase PF00491.16 GAK68411.1 - 4.5e-80 268.9 0.1 5.3e-80 268.6 0.1 1.0 1 0 0 1 1 1 1 Arginase family DEAD PF00270.24 GAK68412.1 - 4.3e-37 127.1 0.2 1.3e-36 125.6 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAK68412.1 - 2.3e-25 88.2 0.0 7.5e-24 83.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAK68412.1 - 1.9e-06 27.8 0.0 4.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAK68412.1 - 0.0042 16.1 0.0 0.0078 15.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Methyltransf_31 PF13847.1 GAK68413.1 - 1.5e-06 27.9 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK68413.1 - 7.8e-06 26.4 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAK68413.1 - 0.00012 21.8 0.0 0.00064 19.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAK68413.1 - 0.00021 21.6 0.0 0.00051 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAK68413.1 - 0.00026 21.4 0.0 0.0011 19.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 GAK68413.1 - 0.003 17.0 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) BRO1 PF03097.13 GAK68414.1 - 7.7e-109 363.8 0.1 1.2e-108 363.2 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAK68414.1 - 4.5e-77 258.9 1.9 1.2e-76 257.5 1.3 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3475 PF11961.3 GAK68414.1 - 0.083 12.7 0.5 0.23 11.3 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) SPX PF03105.14 GAK68414.1 - 3.8 7.2 9.5 1.1 9.0 3.9 2.0 2 0 0 2 2 2 0 SPX domain WGG PF10273.4 GAK68415.1 - 3.7e-23 81.4 0.0 6.4e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Sugar_tr PF00083.19 GAK68417.1 - 4.4e-82 276.0 20.3 5.2e-82 275.8 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAK68417.1 - 3.2e-16 58.9 24.1 3.2e-16 58.9 16.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TPR_4 PF07721.9 GAK68417.1 - 0.046 14.1 0.5 0.12 12.8 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3917 PF13055.1 GAK68417.1 - 2.6 8.3 6.2 12 6.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3917) YIF1 PF03878.10 GAK68418.1 - 2.5e-78 262.5 0.5 3.5e-78 262.0 0.3 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 GAK68418.1 - 0.0078 15.7 11.7 0.028 13.9 8.2 1.8 1 1 0 1 1 1 1 Yip1 domain UCR_14kD PF02271.11 GAK68419.1 - 3e-40 136.2 1.3 3.5e-40 136.0 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Methyltransf_28 PF02636.12 GAK68420.1 - 1.4e-70 237.5 0.0 2.9e-70 236.5 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Amino_oxidase PF01593.19 GAK68420.1 - 1.5e-22 80.3 1.5 3.8e-22 78.9 1.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAK68420.1 - 3.5e-11 42.9 0.0 9.2e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAK68420.1 - 7.8e-11 41.4 0.0 8.4e-06 24.9 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAK68420.1 - 5e-06 25.2 0.0 0.0057 15.1 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 GAK68420.1 - 3.3e-05 23.6 0.1 0.084 12.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAK68420.1 - 0.00037 20.6 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAK68420.1 - 0.009 14.6 0.0 0.026 13.1 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAK68420.1 - 0.015 15.1 0.0 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAK68420.1 - 0.021 15.1 0.5 7.2 7.1 0.0 3.2 4 0 0 4 4 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAK68420.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NtA PF03146.10 GAK68420.1 - 0.062 12.9 0.0 8.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Agrin NtA domain TPR_14 PF13428.1 GAK68422.1 - 7.2e-09 35.5 8.6 0.0037 17.7 0.3 5.1 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAK68422.1 - 3.7e-07 30.6 5.6 0.22 12.2 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAK68422.1 - 4.4e-05 23.0 4.5 0.0039 16.8 3.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 GAK68422.1 - 6.4e-05 22.5 6.1 0.059 13.3 0.2 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAK68422.1 - 0.0001 22.2 1.2 0.72 10.2 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAK68422.1 - 0.0012 19.0 5.8 0.23 11.8 1.6 4.0 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAK68422.1 - 0.01 15.5 1.9 3 7.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAK68422.1 - 0.017 14.9 8.3 0.8 9.5 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAK68422.1 - 0.063 13.4 3.4 0.2 11.8 2.3 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAK68422.1 - 0.43 11.1 5.6 26 5.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TIM PF00121.13 GAK68424.1 - 1.5e-58 197.7 0.0 1.8e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 GAK68425.1 - 7.1e-43 145.6 0.6 8.1e-43 145.4 0.4 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.1 GAK68425.1 - 0.032 14.0 0.8 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) Arm PF00514.18 GAK68426.1 - 2.1e-05 24.1 1.0 0.00043 20.0 0.1 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Zn_clus PF00172.13 GAK68427.1 - 9.4e-07 28.6 12.7 1.8e-06 27.7 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 GAK68428.1 - 9.5e-10 38.3 0.0 3.1e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAK68428.1 - 1.7e-08 33.6 0.0 0.0022 16.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 GAK68428.1 - 1.9e-06 28.0 2.3 3e-05 24.0 1.5 2.7 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAK68428.1 - 0.00045 19.5 0.1 0.00074 18.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 GAK68428.1 - 0.00088 18.2 0.0 0.11 11.3 0.0 2.4 3 0 0 3 3 3 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAK68428.1 - 0.0015 17.3 0.1 0.042 12.5 0.0 2.7 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAK68428.1 - 0.0058 16.5 0.9 0.0058 16.5 0.6 2.5 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAK68428.1 - 0.023 14.3 1.4 0.34 10.5 0.2 2.2 1 1 0 2 2 2 0 KR domain Abhydrolase_6 PF12697.2 GAK68429.1 - 5.4e-31 108.2 0.1 8.2e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK68429.1 - 1.5e-10 40.9 0.0 3.5e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAK68429.1 - 8.8e-09 35.2 0.0 0.0081 15.7 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 GAK68429.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 GAK68429.1 - 0.004 16.9 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Rad60-SLD_2 PF13881.1 GAK68430.1 - 1.2e-13 50.9 0.3 4.2e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like WD40 PF00400.27 GAK68431.1 - 2e-27 94.0 0.4 1.6e-07 30.9 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 GAK68431.1 - 0.1 10.6 0.2 1.5 6.8 0.0 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Dopey_N PF04118.9 GAK68433.1 - 2e-110 368.4 0.0 4.7e-110 367.2 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal RRM_1 PF00076.17 GAK68434.1 - 3.3e-15 55.4 0.0 4.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK68434.1 - 1.1e-12 47.7 0.0 1.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK68434.1 - 3.5e-09 36.3 0.0 5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Uds1 PF15456.1 GAK68435.1 - 1e-18 67.4 3.1 1e-18 67.4 2.2 10.0 5 2 3 9 9 9 2 Up-regulated During Septation COPIIcoated_ERV PF07970.7 GAK68436.1 - 6.6e-69 231.9 0.2 1.1e-68 231.1 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAK68436.1 - 1.6e-33 114.5 0.2 6e-33 112.7 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) WD40 PF00400.27 GAK68437.1 - 5e-35 118.1 0.3 1e-06 28.3 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 GAK68437.1 - 4.4e-07 29.7 0.7 3.5e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Tox-GHH PF15636.1 GAK68437.1 - 0.57 9.8 3.2 26 4.5 0.0 3.7 4 0 0 4 4 4 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin HPP PF04982.8 GAK68438.1 - 5.3e-37 126.3 6.9 9.8e-37 125.4 4.8 1.5 1 0 0 1 1 1 1 HPP family YL1_C PF08265.6 GAK68438.1 - 0.023 14.2 0.3 0.062 12.8 0.1 1.8 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain CoA_binding_3 PF13727.1 GAK68438.1 - 0.066 13.0 0.3 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 CoA-binding domain Fis1_TPR_C PF14853.1 GAK68439.1 - 8.2e-25 86.4 0.6 1.3e-24 85.8 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 GAK68439.1 - 4.6e-17 61.0 0.0 9.1e-17 60.0 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 GAK68439.1 - 0.00032 20.3 0.2 0.0008 19.1 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAK68439.1 - 0.0031 18.1 0.0 0.0073 16.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAK68439.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.1 GAK68439.1 - 0.09 12.7 0.1 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat PX PF00787.19 GAK68440.1 - 2e-21 75.8 0.4 3.9e-21 74.9 0.3 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 GAK68440.1 - 2.7e-06 26.8 0.8 0.66 9.1 0.3 3.2 3 0 0 3 3 3 3 Vps5 C terminal like BAR PF03114.13 GAK68440.1 - 0.0028 17.1 0.1 0.01 15.3 0.1 1.9 1 1 0 1 1 1 1 BAR domain HMG_box PF00505.14 GAK68442.1 - 3.3e-20 72.1 13.5 6.8e-12 45.4 0.4 3.6 2 2 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 GAK68442.1 - 5.8e-18 65.0 12.4 4.4e-11 42.9 0.2 3.0 3 0 0 3 3 3 2 HMG-box domain Tol_Tol_Ttg2 PF05494.7 GAK68442.1 - 0.036 13.6 1.6 1 8.8 0.2 2.3 2 0 0 2 2 2 0 Toluene tolerance, Ttg2 KRAB PF01352.22 GAK68442.1 - 1.7 8.1 3.3 7 6.1 0.2 2.4 2 0 0 2 2 2 0 KRAB box GCV_T PF01571.16 GAK68444.1 - 2.8e-17 62.7 0.0 1e-16 60.9 0.0 1.9 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAK68444.1 - 1.4e-06 28.2 0.0 3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Poty_PP PF08440.5 GAK68444.1 - 0.091 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein DUF2416 PF10315.4 GAK68446.1 - 3.4e-10 40.1 0.5 5.9e-10 39.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2416) Chitin_synth_2 PF03142.10 GAK68447.1 - 2.4e-254 844.6 0.0 3.2e-254 844.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.23 GAK68447.1 - 1.4e-24 85.6 0.0 3.8e-16 58.6 0.0 2.5 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 GAK68447.1 - 8.8e-18 63.8 0.0 5.5e-15 54.8 0.1 2.4 2 0 0 2 2 2 2 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 GAK68447.1 - 8.3e-15 55.2 0.0 8.7e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAK68447.1 - 1.6e-14 54.0 6.1 1.6e-14 54.0 4.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAK68447.1 - 2.4e-06 27.3 0.1 0.0019 17.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAK68447.1 - 2.8e-05 23.4 0.0 8.4e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1622 PF07784.6 GAK68447.1 - 0.043 13.4 2.2 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) Jiv90 PF14901.1 GAK68447.1 - 0.15 12.0 0.3 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone PAT1 PF09770.4 GAK68447.1 - 5.7 5.0 13.9 8.1 4.5 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_63 PF03200.11 GAK68448.1 - 1.2e-07 30.0 2.7 4.2e-06 24.9 0.1 3.9 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase Pro_isomerase PF00160.16 GAK68449.1 - 1.1e-33 116.5 0.0 2.3e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 GAK68449.1 - 6.2e-05 23.2 1.2 6.2e-05 23.2 0.8 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4604) XAP5 PF04921.9 GAK68449.1 - 0.014 14.9 2.8 0.029 13.9 1.9 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator NUDIX PF00293.23 GAK68450.1 - 6.2e-11 42.0 0.0 9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RRM_1 PF00076.17 GAK68451.1 - 2.7e-15 55.7 0.1 4.2e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK68451.1 - 2.9e-12 46.3 0.0 4.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK68451.1 - 9.7e-10 38.1 0.1 1.7e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAK68451.1 - 0.043 13.5 0.6 3.2 7.5 0.0 2.6 2 1 1 3 3 3 0 Limkain b1 Cpl-7 PF08230.6 GAK68451.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain F-box-like PF12937.2 GAK68452.1 - 0.0023 17.5 0.1 0.0065 16.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAK68452.1 - 0.0046 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 GAK68452.1 - 0.069 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Nop14 PF04147.7 GAK68452.1 - 0.22 9.4 7.9 0.33 8.8 5.5 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAK68452.1 - 0.65 7.9 9.2 1.1 7.2 6.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2146 PF10220.4 GAK68452.1 - 2 6.2 4.8 3.1 5.6 3.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RRN3 PF05327.6 GAK68452.1 - 8.2 4.3 7.2 12 3.8 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EF-hand_1 PF00036.27 GAK68453.1 - 5.9e-42 137.7 12.6 3.8e-10 38.3 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAK68453.1 - 1.9e-37 127.2 3.4 1.9e-20 72.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAK68453.1 - 1.8e-33 113.9 11.6 8.4e-17 60.5 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 GAK68453.1 - 2.4e-31 104.7 7.4 1.2e-09 37.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAK68453.1 - 1.9e-28 96.4 7.7 3.2e-07 29.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 GAK68453.1 - 2.3e-14 53.0 0.1 1.8e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 GAK68453.1 - 2.4e-10 40.0 1.2 3.1e-05 23.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 GAK68453.1 - 4.3e-09 36.3 0.0 0.00041 20.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 GAK68453.1 - 7.2e-08 31.9 0.1 0.016 14.8 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 GAK68453.1 - 6.3e-06 26.0 1.0 7.4e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 GAK68453.1 - 0.00073 18.9 1.4 0.00085 18.7 1.0 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 GAK68453.1 - 0.00082 18.9 0.2 0.12 11.9 0.0 2.6 1 1 0 2 2 2 1 Caleosin related protein EF-hand_like PF09279.6 GAK68453.1 - 0.0018 18.2 0.7 0.014 15.3 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 GAK68453.1 - 0.0075 16.0 0.2 0.6 9.8 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB Poly_export PF02563.11 GAK68453.1 - 0.017 14.9 0.1 3.5 7.4 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.5 GAK68453.1 - 0.021 14.5 0.3 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain SapB_1 PF05184.10 GAK68453.1 - 0.047 13.5 0.6 33 4.4 0.0 3.6 4 0 0 4 4 4 0 Saposin-like type B, region 1 RNA_pol_Rpb4 PF03874.11 GAK68453.1 - 0.047 13.6 1.1 5.7 6.9 0.0 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 LNS2 PF08235.8 GAK68453.1 - 0.066 12.7 0.1 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 GAK68453.1 - 0.11 12.0 0.1 0.79 9.2 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 GAK68453.1 - 0.12 12.7 1.1 18 5.7 0.1 2.5 1 1 2 3 3 3 0 Toprim-like VCBS PF13517.1 GAK68453.1 - 1.9 8.9 5.9 16 5.9 0.3 2.5 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RloB PF13707.1 GAK68453.1 - 4.5 6.8 5.4 5.1 6.7 1.4 2.3 1 1 1 2 2 2 0 RloB-like protein Mito_carr PF00153.22 GAK68454.1 - 6.3e-67 221.3 2.4 2.9e-22 78.1 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein GPI-anchored PF10342.4 GAK68455.1 - 8.6e-11 42.1 0.2 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 GAK68455.1 - 0.036 13.5 0.2 0.054 12.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) AAA PF00004.24 GAK68456.1 - 1.8e-43 147.8 0.0 3e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAK68456.1 - 2.9e-07 30.6 0.0 8.1e-06 25.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 GAK68456.1 - 5.8e-07 29.5 0.0 4.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAK68456.1 - 5.9e-07 29.2 0.1 1.3e-05 24.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAK68456.1 - 2.8e-06 27.4 0.0 0.001 19.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 GAK68456.1 - 8.5e-06 24.9 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAK68456.1 - 0.00019 21.0 0.1 0.00048 19.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 GAK68456.1 - 0.00061 18.7 0.0 0.0016 17.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAK68456.1 - 0.0009 20.0 1.2 0.0028 18.4 0.3 2.4 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 GAK68456.1 - 0.0015 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAK68456.1 - 0.0024 17.0 0.0 0.0049 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 GAK68456.1 - 0.0031 16.2 0.0 0.0057 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 GAK68456.1 - 0.0032 17.3 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAK68456.1 - 0.0033 16.8 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 GAK68456.1 - 0.0048 17.0 0.0 0.0099 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 GAK68456.1 - 0.0055 16.3 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAK68456.1 - 0.0057 16.9 1.4 0.017 15.3 0.0 2.5 3 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 GAK68456.1 - 0.0076 15.7 0.0 0.028 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF4200 PF13863.1 GAK68456.1 - 0.0086 16.0 0.7 0.0086 16.0 0.5 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF4200) Zeta_toxin PF06414.7 GAK68456.1 - 0.0098 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 GAK68456.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YkyA PF10368.4 GAK68456.1 - 0.011 15.0 0.9 0.021 14.1 0.6 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Arch_ATPase PF01637.13 GAK68456.1 - 0.013 15.1 0.0 0.19 11.4 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 GAK68456.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 GAK68456.1 - 0.018 14.8 0.0 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 GAK68456.1 - 0.029 13.7 0.2 0.17 11.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 GAK68456.1 - 0.03 13.9 0.0 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 GAK68456.1 - 0.032 13.4 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 GAK68456.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAK68456.1 - 0.042 12.9 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 GAK68456.1 - 0.049 13.6 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 GAK68456.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 GAK68456.1 - 0.06 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.7 GAK68456.1 - 0.083 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 GAK68456.1 - 0.099 12.1 0.2 0.38 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAK68456.1 - 0.19 12.0 3.6 6.3 7.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain TPR_1 PF00515.23 GAK68456.1 - 7.2 6.4 6.8 0.6 9.8 0.6 2.3 3 0 0 3 3 1 0 Tetratricopeptide repeat Clathrin PF00637.15 GAK68457.1 - 7.3e-210 687.0 27.2 9.4e-33 112.8 0.1 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 GAK68457.1 - 2.6e-34 115.1 1.7 7.7e-06 25.8 0.0 7.6 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 GAK68457.1 - 3.2e-32 110.2 0.1 1.1e-31 108.5 0.0 2.0 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 GAK68457.1 - 4e-11 41.6 0.1 1.1e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 GAK68457.1 - 0.0028 16.5 5.2 0.16 10.7 0.0 4.7 5 0 0 5 5 5 1 Coatomer WD associated region TPR_1 PF00515.23 GAK68457.1 - 0.017 14.6 2.9 14 5.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAK68457.1 - 0.034 14.0 11.7 1.4 8.8 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAK68457.1 - 0.11 12.4 9.5 33 4.7 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAK68457.1 - 0.28 11.9 15.0 24 5.9 0.1 8.9 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAK68457.1 - 0.33 10.8 7.6 28 4.8 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Opi1 PF08618.5 GAK68458.1 - 4.6e-163 543.1 5.9 4.6e-163 543.1 4.1 3.5 3 1 0 4 4 4 1 Transcription factor Opi1 Perilipin PF03036.11 GAK68458.1 - 0.0013 17.6 2.9 0.0018 17.1 0.0 2.2 2 0 0 2 2 2 1 Perilipin family Cullin PF00888.17 GAK68459.1 - 9.1e-143 476.8 0.0 1e-133 446.9 0.0 2.3 3 0 0 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.4 GAK68459.1 - 6.8e-28 96.2 1.8 1.8e-27 94.9 1.3 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Ndufs5 PF10200.4 GAK68459.1 - 0.081 12.9 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa MarR PF01047.17 GAK68459.1 - 0.097 12.3 0.5 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 MarR family Zn_clus PF00172.13 GAK68461.1 - 1.8e-05 24.5 6.7 3.2e-05 23.7 4.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_10 PF05971.7 GAK68462.1 - 1.2e-37 129.6 0.0 2.3e-35 122.2 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF890) CENP-O PF09496.5 GAK68462.1 - 3.4e-25 88.0 0.0 6.2e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Methyltransf_18 PF12847.2 GAK68462.1 - 0.00049 20.6 0.2 0.0025 18.3 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain cNMP_binding PF00027.24 GAK68463.1 - 2e-40 136.4 0.0 9.3e-19 67.0 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 GAK68463.1 - 4.1e-15 54.9 0.3 7.9e-15 54.0 0.2 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.6 GAK68463.1 - 0.091 12.2 1.0 0.7 9.4 0.1 2.6 3 0 0 3 3 3 0 Cupin domain Mt_ATP-synt_D PF05873.7 GAK68464.1 - 3.3e-08 33.3 0.6 0.00058 19.5 0.1 2.2 2 0 0 2 2 2 2 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.4 GAK68464.1 - 0.055 13.5 0.7 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DivIC PF04977.10 GAK68464.1 - 0.33 10.4 3.3 2.5 7.6 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator EzrA PF06160.7 GAK68464.1 - 0.45 8.6 3.6 1.3 7.0 0.4 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HemX PF04375.9 GAK68464.1 - 0.69 8.4 7.1 0.38 9.2 3.3 1.6 2 0 0 2 2 2 0 HemX DUF2570 PF10828.3 GAK68464.1 - 0.92 9.1 4.6 0.47 10.0 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Ribosomal_S25 PF03297.10 GAK68465.1 - 9.5e-42 141.3 2.6 1e-41 141.1 1.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 GAK68465.1 - 0.014 14.7 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 GAK68465.1 - 0.062 13.0 0.1 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 MarR family BioT2 PF15368.1 GAK68465.1 - 0.063 13.0 0.4 0.065 13.0 0.3 1.2 1 0 0 1 1 1 0 Spermatogenesis family BioT2 MarR_2 PF12802.2 GAK68465.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 MarR family BolA PF01722.13 GAK68466.1 - 4.1e-15 55.4 0.0 5.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein GTP_cyclohydroI PF01227.17 GAK68467.1 - 6.5e-73 243.8 0.2 8.7e-73 243.4 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 GAK68467.1 - 0.003 17.4 0.0 0.0077 16.1 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 GAK68467.1 - 0.015 15.0 0.1 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MutS_II PF05188.12 GAK68468.1 - 5.3e-05 23.2 0.0 0.00011 22.2 0.0 1.5 2 0 0 2 2 2 1 MutS domain II WD40 PF00400.27 GAK68469.1 - 4.4e-39 130.9 20.9 2.9e-10 39.6 0.2 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF3312 PF11768.3 GAK68469.1 - 0.00051 18.4 0.0 0.0021 16.3 0.0 1.9 2 1 0 3 3 3 1 Protein of unknown function (DUF3312) IKI3 PF04762.7 GAK68469.1 - 0.0056 14.5 0.1 0.0074 14.1 0.1 1.3 1 0 0 1 1 1 1 IKI3 family PQQ_3 PF13570.1 GAK68469.1 - 0.09 13.0 11.8 0.19 12.0 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain DUF4613 PF15390.1 GAK68469.1 - 0.3 9.2 0.3 0.41 8.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF3543 PF12063.3 GAK68470.1 - 5e-57 192.8 0.0 7.7e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 GAK68470.1 - 3.8e-56 190.1 0.0 5.3e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68470.1 - 1.6e-40 138.8 0.0 4e-40 137.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK68470.1 - 0.013 14.5 0.0 0.039 12.9 0.0 1.8 1 1 0 1 1 1 0 Kinase-like DUF3425 PF11905.3 GAK68471.1 - 9.9e-14 51.3 0.1 2.2e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAK68471.1 - 0.00016 21.5 11.0 0.0003 20.6 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 GAK68471.1 - 0.0041 17.3 10.9 0.0077 16.5 7.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 GAK68471.1 - 0.0099 15.6 12.1 0.017 14.9 8.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF4140 PF13600.1 GAK68471.1 - 0.14 12.6 3.8 0.3 11.5 2.6 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DJ-1_PfpI PF01965.19 GAK68472.1 - 1.5e-12 47.1 0.0 3.2e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family RVT_1 PF00078.22 GAK68473.1 - 2.1e-09 37.0 0.0 4.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Trypan_PARP PF05887.6 GAK68473.1 - 0.056 13.2 12.0 0.095 12.5 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Arrestin_N PF00339.24 GAK68474.1 - 0.0018 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF218 PF02698.12 GAK68475.1 - 0.032 13.7 0.2 0.09 12.2 0.0 1.8 2 0 0 2 2 2 0 DUF218 domain Ribosomal_L7Ae PF01248.21 GAK68476.1 - 2.5e-27 94.1 0.1 3.2e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 GAK68476.1 - 0.0061 16.3 0.0 0.0073 16.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 HTH_Crp_2 PF13545.1 GAK68476.1 - 0.036 13.8 0.0 0.16 11.7 0.0 2.1 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain PELOTA_1 PF15608.1 GAK68476.1 - 0.041 13.6 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Phenol_Hydrox PF02332.13 GAK68476.1 - 0.061 12.6 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase MutS_V PF00488.16 GAK68477.1 - 2.4e-58 197.3 0.0 4.1e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAK68477.1 - 2.4e-14 53.5 1.0 2.4e-14 53.5 0.7 2.9 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.13 GAK68477.1 - 0.00025 21.1 0.3 0.00048 20.2 0.2 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 GAK68477.1 - 0.0011 18.5 0.0 0.0034 16.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 GAK68477.1 - 0.011 16.1 0.1 0.036 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAK68477.1 - 0.023 14.8 0.2 0.26 11.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 GAK68477.1 - 0.035 14.0 0.0 0.096 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAK68477.1 - 0.04 13.3 0.0 0.14 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAK68477.1 - 0.083 12.3 2.3 0.41 10.0 0.0 2.9 3 2 1 4 4 4 0 AAA-like domain G-alpha PF00503.15 GAK68477.1 - 0.35 9.5 2.6 1.3 7.6 0.0 2.8 3 1 0 3 3 3 0 G-protein alpha subunit zf-Tim10_DDP PF02953.10 GAK68478.1 - 3.1e-19 68.0 3.2 4.8e-19 67.4 2.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DFF-C PF09033.5 GAK68478.1 - 0.09 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain eIF-6 PF01912.13 GAK68479.1 - 4.4e-83 277.2 0.3 6.5e-83 276.7 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family PRKCSH-like PF12999.2 GAK68480.1 - 1e-51 174.9 4.6 1e-51 174.9 3.2 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 GAK68480.1 - 2.4e-31 108.2 0.2 9.7e-31 106.3 0.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 GAK68480.1 - 2.9e-10 40.7 0.6 6.2e-10 39.7 0.4 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein V_ATPase_I PF01496.14 GAK68480.1 - 0.0072 14.2 0.2 0.011 13.6 0.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DivIVA PF05103.8 GAK68480.1 - 0.13 12.3 6.8 5.1 7.1 4.3 3.2 2 1 0 2 2 2 0 DivIVA protein IFP_35_N PF07334.8 GAK68480.1 - 0.17 11.8 0.9 19 5.3 0.2 2.5 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ldl_recept_a PF00057.13 GAK68480.1 - 0.6 10.0 18.5 0.53 10.2 0.9 3.3 3 1 0 3 3 3 0 Low-density lipoprotein receptor domain class A Enkurin PF13864.1 GAK68480.1 - 0.81 9.9 4.6 1.9 8.7 0.3 2.7 1 1 1 2 2 2 0 Calmodulin-binding DivIC PF04977.10 GAK68480.1 - 1.4 8.4 7.4 7.1 6.1 1.2 2.5 1 1 1 2 2 2 0 Septum formation initiator EnY2 PF10163.4 GAK68482.1 - 1.2e-20 73.2 0.0 1.4e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 RecO_C PF02565.10 GAK68482.1 - 0.026 14.3 0.2 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal RNA_Me_trans PF04252.8 GAK68483.1 - 7e-23 81.0 0.0 5.1e-20 71.7 0.0 3.0 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Pkinase PF00069.20 GAK68484.1 - 1.2e-68 231.0 0.0 1.7e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68484.1 - 2.2e-34 118.6 0.0 3.6e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK68484.1 - 0.00035 20.3 0.0 0.0033 17.2 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAK68484.1 - 0.0057 15.7 0.0 0.0098 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAK68484.1 - 0.0096 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 GAK68484.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 GAK68484.1 - 0.16 11.3 0.0 0.54 9.5 0.0 1.6 1 1 0 1 1 1 0 RIO1 family HIG_1_N PF04588.8 GAK68485.1 - 9.7e-06 25.2 1.5 1.9e-05 24.3 1.1 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region NDUF_B8 PF05821.6 GAK68487.1 - 9.1e-09 35.2 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DGF-1_5 PF11038.3 GAK68487.1 - 0.11 11.7 0.9 0.27 10.4 0.6 1.6 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Metallophos PF00149.23 GAK68488.1 - 4.3e-38 130.7 0.8 3.9e-30 104.7 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase ELO PF01151.13 GAK68489.1 - 2e-59 200.9 17.4 2.7e-59 200.5 12.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2231 PF09990.4 GAK68489.1 - 0.13 12.6 2.2 1.3 9.4 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Methyltransf_16 PF10294.4 GAK68490.1 - 2.4e-16 59.6 0.0 7e-14 51.6 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 GAK68490.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAK68490.1 - 0.099 13.2 0.1 0.22 12.0 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 GAK68492.1 - 0.00014 21.8 0.3 0.00031 20.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family ABC_tran PF00005.22 GAK68494.1 - 3.8e-44 150.3 0.1 1.1e-21 77.5 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAK68494.1 - 3e-16 60.2 0.2 0.0051 16.8 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 GAK68494.1 - 9.3e-12 44.6 2.1 0.2 10.8 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAK68494.1 - 6.7e-10 38.3 0.4 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.1 GAK68494.1 - 3.6e-09 36.7 0.6 0.00014 22.0 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats AAA_17 PF13207.1 GAK68494.1 - 8e-07 29.9 0.0 0.0054 17.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain CLASP_N PF12348.3 GAK68494.1 - 1.3e-06 27.9 0.1 5.2e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 CLASP N terminal AAA_10 PF12846.2 GAK68494.1 - 1.8e-06 27.6 0.1 0.078 12.3 0.0 3.6 4 1 0 4 4 3 2 AAA-like domain AAA_22 PF13401.1 GAK68494.1 - 3.3e-06 27.2 0.0 0.076 13.1 0.0 4.0 5 0 0 5 5 3 2 AAA domain Miro PF08477.8 GAK68494.1 - 4.9e-06 27.0 0.0 0.03 14.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 GAK68494.1 - 7.1e-06 25.8 0.1 0.0055 16.6 0.0 3.5 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit Chromo PF00385.19 GAK68494.1 - 1.1e-05 24.9 0.0 3.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HEAT PF02985.17 GAK68494.1 - 2.6e-05 23.9 1.3 0.1 12.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat AAA_16 PF13191.1 GAK68494.1 - 5.5e-05 23.2 1.3 0.6 10.0 0.0 4.5 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.18 GAK68494.1 - 9.3e-05 22.3 0.0 0.12 12.3 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 GAK68494.1 - 0.00012 22.4 0.2 0.04 14.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAK68494.1 - 0.00024 21.3 0.1 3.2 7.9 0.0 4.7 5 1 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) HEAT_EZ PF13513.1 GAK68494.1 - 0.00026 21.3 1.9 0.089 13.3 0.0 4.6 4 2 2 6 6 5 1 HEAT-like repeat NACHT PF05729.7 GAK68494.1 - 0.00027 20.6 0.2 0.53 9.9 0.0 2.8 3 0 0 3 3 2 2 NACHT domain MobB PF03205.9 GAK68494.1 - 0.00038 20.1 0.1 0.77 9.4 0.1 3.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAK68494.1 - 0.00053 19.8 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAK68494.1 - 0.00081 19.3 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAK68494.1 - 0.00086 18.5 0.0 0.76 8.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 GAK68494.1 - 0.0013 17.8 3.6 7.3 5.5 0.0 4.5 4 1 0 5 5 5 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAK68494.1 - 0.0013 18.2 0.1 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 GAK68494.1 - 0.0015 18.8 0.6 0.042 14.1 0.0 3.7 3 1 0 3 3 2 2 AAA domain NB-ARC PF00931.17 GAK68494.1 - 0.0023 16.8 0.2 1.3 7.8 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain RNA_helicase PF00910.17 GAK68494.1 - 0.0035 17.5 0.0 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 GAK68494.1 - 0.0049 15.6 1.0 0.73 8.5 0.0 2.7 2 0 0 2 2 2 1 ArgK protein DUF87 PF01935.12 GAK68494.1 - 0.005 16.6 6.9 0.18 11.5 0.1 3.9 4 0 0 4 4 3 1 Domain of unknown function DUF87 Arm PF00514.18 GAK68494.1 - 0.0056 16.4 0.3 14 5.7 0.0 4.4 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat AAA_25 PF13481.1 GAK68494.1 - 0.0066 15.8 0.1 6.7 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 GAK68494.1 - 0.02 14.6 5.5 19 4.9 0.0 5.1 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAK68494.1 - 0.033 13.3 0.8 16 4.5 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 GAK68494.1 - 0.035 13.0 0.8 5.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAK68494.1 - 0.036 13.9 0.0 6.9 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 GAK68494.1 - 0.041 13.5 0.1 5.9 6.5 0.0 2.6 2 0 0 2 2 2 0 NTPase cobW PF02492.14 GAK68494.1 - 0.11 11.9 1.5 13 5.1 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 GAK68494.1 - 0.17 10.5 4.4 3.7 6.1 0.0 2.5 3 0 0 3 3 2 0 G-protein alpha subunit DUF3584 PF12128.3 GAK68494.1 - 0.19 8.9 8.3 0.44 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 GAK68494.1 - 0.47 8.8 8.6 1.3 7.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.12 GAK68494.1 - 0.48 9.9 2.7 8.7 5.7 0.1 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 GAK68494.1 - 1.9 8.1 11.0 6.6 6.3 0.6 4.1 4 1 0 4 4 3 0 Archaeal ATPase Pkinase PF00069.20 GAK68495.1 - 3.3e-09 36.2 0.0 5.1e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68495.1 - 1.1e-05 24.6 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HNH_2 PF13391.1 GAK68496.1 - 2.2e-06 27.3 2.6 1e-05 25.2 0.9 2.5 2 1 0 2 2 2 1 HNH endonuclease GMC_oxred_N PF00732.14 GAK68497.1 - 1.5e-71 240.9 0.1 2.1e-71 240.5 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAK68497.1 - 2.5e-33 115.3 0.0 5.9e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 GAK68497.1 - 2.6e-06 27.6 0.2 0.012 15.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAK68497.1 - 2e-05 24.5 0.1 8.4e-05 22.5 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAK68497.1 - 3.2e-05 23.0 0.1 5.7e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAK68497.1 - 3.7e-05 22.7 3.1 0.0004 19.4 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAK68497.1 - 0.00011 21.1 1.8 0.00044 19.2 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Collagen PF01391.13 GAK68497.1 - 0.0025 17.3 10.2 0.005 16.3 7.0 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Pyr_redox_2 PF07992.9 GAK68497.1 - 0.0057 16.5 1.0 0.0082 16.0 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAK68497.1 - 0.028 14.2 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 GAK68497.1 - 0.029 13.4 0.3 0.058 12.4 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.20 GAK68498.1 - 3.6e-61 206.5 3.5 1.6e-41 142.2 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68498.1 - 9.4e-24 83.8 9.1 6e-20 71.4 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 GAK68498.1 - 4.9e-05 22.4 0.1 0.00047 19.2 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 GAK68498.1 - 0.034 14.6 0.1 0.11 12.9 0.1 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.18 GAK68498.1 - 0.041 13.6 0.0 0.041 13.6 0.0 4.1 1 1 2 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAK68498.1 - 0.056 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 GAK68498.1 - 0.15 10.8 0.1 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 EIF4E-T PF10477.4 GAK68498.1 - 2 7.1 21.8 3 6.5 15.1 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Myosin_head PF00063.16 GAK68499.1 - 7.2e-229 761.3 4.0 1.2e-228 760.6 2.8 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAK68499.1 - 4.7e-43 146.8 0.0 8.2e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 GAK68499.1 - 9.2e-11 41.1 0.1 2.2e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAK68499.1 - 5.1e-10 38.5 2.1 6.7e-10 38.2 0.3 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 GAK68499.1 - 2.1e-09 36.7 0.1 4.4e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 GAK68499.1 - 0.0032 17.6 1.3 0.0079 16.3 0.9 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 GAK68499.1 - 0.0036 17.4 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAK68499.1 - 0.016 14.3 0.0 0.051 12.6 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 GAK68499.1 - 0.025 15.4 0.0 0.12 13.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 GAK68499.1 - 0.059 12.6 0.2 4.8 6.4 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 GAK68499.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 GAK68499.1 - 0.2 11.5 0.0 0.62 10.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Melibiase PF02065.13 GAK68500.1 - 6.1e-129 430.1 0.0 7.6e-129 429.8 0.0 1.1 1 0 0 1 1 1 1 Melibiase Pkinase PF00069.20 GAK68501.1 - 6e-51 173.0 0.0 9e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68501.1 - 1.3e-32 112.8 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK68501.1 - 3e-06 27.1 0.1 2.6e-05 24.1 0.0 2.2 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAK68501.1 - 0.018 13.9 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 GAK68501.1 - 0.036 12.8 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Apt1 PF10351.4 GAK68502.1 - 0.44 9.3 4.9 0.58 8.9 3.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDK2AP PF09806.4 GAK68502.1 - 2.7 8.1 9.9 0.82 9.8 4.4 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Period_C PF12114.3 GAK68502.1 - 5.6 6.5 15.2 9.2 5.8 10.5 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region AF-4 PF05110.8 GAK68502.1 - 5.7 4.6 26.3 8.1 4.1 18.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.4 GAK68502.1 - 6 5.0 9.3 8.3 4.5 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4614 PF15391.1 GAK68502.1 - 8.7 6.0 12.0 17 5.1 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) EXS PF03124.9 GAK68503.1 - 1.5e-78 264.2 18.4 2e-78 263.8 12.7 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 GAK68503.1 - 3.6e-46 158.1 0.0 6e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 SPX domain Plasmid_stabil PF05016.9 GAK68503.1 - 0.025 14.9 0.6 0.35 11.2 0.2 2.8 2 0 0 2 2 2 0 Plasmid stabilisation system protein Vps51 PF08700.6 GAK68504.1 - 1.5e-17 63.2 0.2 4e-17 61.8 0.2 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 GAK68504.1 - 0.002 18.0 2.0 0.0021 17.9 0.1 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Bac_rhodopsin PF01036.13 GAK68506.1 - 9.2e-46 155.9 12.6 1.2e-45 155.5 8.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Trep_Strep PF09605.5 GAK68506.1 - 0.28 10.8 7.4 0.13 11.9 2.6 1.9 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1304 PF06993.7 GAK68506.1 - 2.9 7.6 8.0 4.2 7.1 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) HEM4 PF02602.10 GAK68507.1 - 3.3e-15 55.9 0.1 1.3e-09 37.6 0.0 3.2 2 1 0 2 2 2 2 Uroporphyrinogen-III synthase HemD SNF2_N PF00176.18 GAK68512.1 - 8.6e-71 238.1 0.0 1.2e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.3 GAK68512.1 - 7.3e-42 143.5 0.2 1.9e-40 138.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Helicase_C PF00271.26 GAK68512.1 - 2.7e-13 49.5 0.0 7.5e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 GAK68512.1 - 6.3e-05 22.7 14.6 0.0044 16.9 0.3 5.0 5 1 1 6 6 6 2 HEAT repeat Vac14_Fab1_bd PF12755.2 GAK68512.1 - 0.008 16.5 0.1 0.037 14.4 0.0 2.1 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAK68512.1 - 0.02 15.3 16.6 2 9.0 0.2 5.1 4 1 1 5 5 5 0 HEAT-like repeat HHH PF00633.18 GAK68513.1 - 9.3e-05 21.9 0.1 0.00025 20.5 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif GTPase_Cys_C PF12631.2 GAK68513.1 - 0.082 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Syntaxin PF00804.20 GAK68514.1 - 4e-15 55.8 14.4 8.1e-15 54.8 2.8 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 GAK68514.1 - 3e-11 42.8 15.1 3.2e-11 42.7 5.3 2.8 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.6 GAK68514.1 - 0.0014 16.2 9.5 0.033 11.7 0.2 2.1 2 0 0 2 2 2 2 Prominin MCPsignal PF00015.16 GAK68514.1 - 0.002 17.6 12.8 0.0078 15.7 1.8 2.4 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Allexi_40kDa PF05549.6 GAK68514.1 - 0.0032 16.8 5.0 0.0058 15.9 0.7 2.1 2 0 0 2 2 2 1 Allexivirus 40kDa protein TB2_DP1_HVA22 PF03134.14 GAK68514.1 - 0.0035 17.0 0.1 0.0065 16.1 0.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3611 PF12263.3 GAK68514.1 - 0.0064 15.9 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Shisa PF13908.1 GAK68514.1 - 0.018 15.2 0.2 0.018 15.2 0.2 2.8 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF2077 PF09850.4 GAK68514.1 - 0.026 13.9 0.1 0.026 13.9 0.1 2.4 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2077) PBP1_TM PF14812.1 GAK68514.1 - 0.05 13.9 0.1 0.05 13.9 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2116 PF09889.4 GAK68514.1 - 0.059 13.1 0.5 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4094 PF13334.1 GAK68514.1 - 0.14 12.5 0.1 0.14 12.5 0.1 3.1 2 1 1 4 4 3 0 Domain of unknown function (DUF4094) Spectrin PF00435.16 GAK68514.1 - 0.52 10.6 11.1 0.5 10.6 0.1 3.0 3 1 0 3 3 3 0 Spectrin repeat DASH_Dam1 PF08653.5 GAK68514.1 - 0.6 9.9 2.5 0.83 9.4 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Syntaxin_2 PF14523.1 GAK68514.1 - 0.98 9.4 18.7 0.38 10.8 6.1 2.9 2 1 0 2 2 2 0 Syntaxin-like protein DUF3708 PF12501.3 GAK68514.1 - 1.1 9.0 6.0 1.1 9.1 0.4 2.5 1 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter Synaptobrevin PF00957.16 GAK68514.1 - 3.3 7.3 12.7 0.67 9.6 2.2 2.8 2 1 0 2 2 2 0 Synaptobrevin Tropomyosin PF00261.15 GAK68514.1 - 4.4 6.3 18.6 2.2 7.2 4.2 2.7 2 1 1 3 3 3 0 Tropomyosin TBPIP PF07106.8 GAK68514.1 - 6.4 6.3 15.5 3.6 7.1 2.6 2.6 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mis12 PF05859.7 GAK68515.1 - 1.9e-17 63.4 0.0 3.4e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 Mis12 protein Proteasome PF00227.21 GAK68516.1 - 8.1e-28 97.0 0.0 1.1e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SAMP PF05924.6 GAK68516.1 - 0.089 11.9 0.8 0.18 11.0 0.5 1.5 1 0 0 1 1 1 0 SAMP Motif DUF2461 PF09365.5 GAK68517.1 - 1.1e-35 122.9 0.1 2e-35 122.1 0.1 1.4 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) NAP PF00956.13 GAK68517.1 - 0.36 9.8 5.0 0.074 12.1 0.4 1.8 1 1 0 2 2 2 0 Nucleosome assembly protein (NAP) Ribosomal_60s PF00428.14 GAK68517.1 - 3.5 8.0 10.9 1.6 9.1 2.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Transaldolase PF00923.14 GAK68518.1 - 4e-94 314.9 0.3 5e-94 314.6 0.2 1.1 1 0 0 1 1 1 1 Transaldolase Pro_isomerase PF00160.16 GAK68518.1 - 1.1e-44 152.3 0.0 2.1e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.2 GAK68519.1 - 0.058 13.1 0.8 0.14 11.8 0.5 1.7 1 1 0 1 1 1 0 F-box-like F-box PF00646.28 GAK68519.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 F-box domain DUF3367 PF11847.3 GAK68519.1 - 0.15 10.0 2.1 0.22 9.4 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) TPR_2 PF07719.12 GAK68520.1 - 6.2e-27 91.3 19.5 0.00055 19.6 0.1 9.9 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 GAK68520.1 - 1.3e-23 82.3 16.9 1.6e-09 37.2 0.0 7.8 4 1 3 8 8 8 7 TPR repeat TPR_1 PF00515.23 GAK68520.1 - 5e-23 79.6 1.9 0.00041 19.8 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 GAK68520.1 - 4.3e-19 68.4 12.2 9e-09 35.3 1.1 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAK68520.1 - 1.7e-12 47.1 19.8 2.3e-05 24.2 0.0 7.3 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAK68520.1 - 1.6e-10 39.9 0.0 0.42 10.5 0.0 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAK68520.1 - 5e-09 36.5 6.1 2e-07 31.5 0.7 7.4 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAK68520.1 - 3.6e-08 32.9 0.9 0.68 10.2 0.0 6.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAK68520.1 - 4.7e-08 32.9 38.1 0.022 15.3 0.1 9.2 6 4 4 10 10 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 GAK68520.1 - 2.7e-05 24.3 17.1 0.34 11.4 0.0 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAK68520.1 - 0.00017 21.8 24.7 0.025 14.9 0.3 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAK68520.1 - 0.00075 19.3 18.5 8.3 6.4 0.4 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAK68520.1 - 0.0022 17.8 29.6 0.057 13.2 0.1 6.6 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAK68520.1 - 0.027 14.2 17.4 0.16 11.8 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAK68520.1 - 4.7 7.1 11.2 69 3.4 0.0 5.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Diphthamide_syn PF01866.12 GAK68521.1 - 1.1e-60 205.4 0.0 1.7e-30 106.3 0.0 3.1 2 1 0 3 3 3 3 Putative diphthamide synthesis protein Zn_clus PF00172.13 GAK68523.1 - 4e-09 36.2 12.5 6.8e-09 35.4 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 GAK68524.1 - 0.77 9.0 4.7 0.1 11.9 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator BMP2K_C PF15282.1 GAK68525.1 - 0.91 9.6 10.3 1.1 9.3 7.1 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus SEEK1 PF15357.1 GAK68526.1 - 0.033 14.0 0.7 0.059 13.2 0.5 1.5 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 Abhydrolase_6 PF12697.2 GAK68528.1 - 6.9e-19 68.6 2.6 9.7e-19 68.1 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK68528.1 - 4.2e-11 42.7 0.2 7.1e-11 42.0 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 GAK68528.1 - 7.8e-06 24.9 0.0 0.00016 20.6 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 GAK68528.1 - 3.6e-05 23.4 0.6 0.00087 18.9 0.1 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAK68528.1 - 5.9e-05 22.3 0.1 0.00031 20.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.6 GAK68528.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Peptidase_S15 PF02129.13 GAK68528.1 - 0.022 14.1 0.1 0.63 9.4 0.0 2.2 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Cupin_3 PF05899.7 GAK68529.1 - 0.0001 21.6 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_2 PF07883.6 GAK68529.1 - 0.00015 21.1 0.4 0.085 12.3 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_6 PF12852.2 GAK68529.1 - 0.0038 16.8 0.1 0.07 12.7 0.0 2.4 2 0 0 2 2 2 1 Cupin Cupin_8 PF13621.1 GAK68529.1 - 0.033 13.6 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Cupin_4 PF08007.7 GAK68529.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein PMI_typeI PF01238.16 GAK68529.1 - 0.087 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphomannose isomerase type I HAD PF12710.2 GAK68532.1 - 8.6e-15 55.4 0.0 1.1e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 GAK68532.1 - 1.3e-09 37.8 0.0 3.6e-09 36.3 0.0 1.6 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 GAK68532.1 - 2.3e-05 24.6 0.0 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAK68532.1 - 0.00018 20.7 0.2 0.0011 18.1 0.1 1.9 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 GAK68532.1 - 0.11 12.8 1.6 0.43 10.9 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.7 GAK68532.1 - 0.12 12.5 0.1 0.62 10.2 0.0 2.3 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Mem_trans PF03547.13 GAK68533.1 - 3.9e-33 114.2 6.7 8.4e-32 109.9 0.0 2.6 2 1 0 2 2 2 2 Membrane transport protein Gly-zipper_Omp PF13488.1 GAK68534.1 - 0.011 15.3 3.5 0.011 15.3 2.5 4.1 4 1 0 4 4 4 0 Glycine zipper Beta-APP PF03494.8 GAK68534.1 - 1.6 8.2 4.2 3.7 7.0 2.9 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Aft1_HRA PF11786.3 GAK68535.1 - 1.9e-16 60.0 10.9 1.9e-16 60.0 7.6 3.8 4 0 0 4 4 4 1 Aft1 HRA domain bZIP_1 PF00170.16 GAK68535.1 - 4.4e-10 39.3 6.5 8.6e-10 38.4 4.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAK68535.1 - 8.9e-07 28.6 8.7 3.1e-06 26.8 6.1 2.0 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 GAK68535.1 - 0.00065 20.1 1.4 0.00065 20.1 1.0 4.3 3 1 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.12 GAK68535.1 - 0.00074 19.7 5.6 0.0019 18.4 3.9 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor Shugoshin_N PF07558.6 GAK68535.1 - 0.046 13.4 0.3 0.087 12.5 0.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.13 GAK68535.1 - 0.51 10.0 2.4 0.32 10.7 0.4 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pox_MCEL PF03291.11 GAK68537.1 - 1.5e-07 30.5 0.0 3.3e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 mRNA capping enzyme BNIP3 PF06553.7 GAK68538.1 - 1.5 8.1 4.6 1.6 8.0 3.2 1.0 1 0 0 1 1 1 0 BNIP3 RRM_1 PF00076.17 GAK68540.1 - 2.5e-58 193.5 0.0 7.9e-19 67.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAK68540.1 - 2.7e-43 145.8 0.0 3.9e-15 55.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAK68540.1 - 1.4e-25 88.8 0.0 6.8e-11 41.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAK68540.1 - 2e-05 24.3 0.0 1 9.2 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 GAK68540.1 - 3e-05 23.6 0.0 0.82 9.4 0.0 3.6 3 1 0 3 3 3 3 Limkain b1 ATP-grasp_2 PF08442.5 GAK68540.1 - 0.0051 16.2 0.0 13 5.0 0.0 3.3 3 0 0 3 3 3 1 ATP-grasp domain bZIP_1 PF00170.16 GAK68541.1 - 9.7e-10 38.2 8.4 2.7e-09 36.8 5.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAK68541.1 - 7.5e-09 35.2 6.4 9.9e-09 34.8 4.0 1.5 1 1 0 1 1 1 1 Basic region leucine zipper Spc7 PF08317.6 GAK68541.1 - 0.002 16.8 1.1 0.0031 16.2 0.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Herpes_BLRF2 PF05812.7 GAK68541.1 - 0.017 14.9 3.4 0.022 14.5 0.1 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Phlebovirus_NSM PF07246.6 GAK68541.1 - 0.057 12.5 2.7 0.088 11.9 1.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF972 PF06156.8 GAK68541.1 - 0.064 13.6 0.3 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HAP1_N PF04849.8 GAK68541.1 - 0.071 12.0 5.2 0.13 11.1 3.6 1.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_Maf PF03131.12 GAK68541.1 - 0.14 12.4 4.6 0.3 11.4 3.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Herpes_UL6 PF01763.11 GAK68541.1 - 0.16 10.1 0.6 0.23 9.6 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.10 GAK68541.1 - 0.17 11.3 2.6 0.38 10.2 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.13 GAK68541.1 - 0.22 11.5 0.5 0.76 9.7 0.2 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family Atg14 PF10186.4 GAK68541.1 - 0.25 10.2 5.2 0.5 9.2 3.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PH PF00169.24 GAK68543.1 - 4.3e-05 23.6 0.0 0.27 11.4 0.0 3.2 3 0 0 3 3 3 2 PH domain PH_9 PF15410.1 GAK68543.1 - 0.0081 16.3 0.1 0.12 12.5 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain Pkinase PF00069.20 GAK68544.1 - 2.5e-65 220.1 0.0 3.5e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68544.1 - 1.2e-28 99.8 0.0 1.8e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAK68544.1 - 0.00012 21.1 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAK68544.1 - 0.042 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAK68544.1 - 0.076 12.7 0.2 2 8.0 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3012 PF11216.3 GAK68544.1 - 0.11 12.2 0.2 9.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) PAT1 PF09770.4 GAK68545.1 - 2.3e-127 426.4 0.5 2.8e-127 426.1 0.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF3847 PF12958.2 GAK68545.1 - 0.32 10.7 5.0 0.082 12.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) G6PD_C PF02781.11 GAK68546.1 - 2e-124 414.2 0.0 2.8e-124 413.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 GAK68546.1 - 9e-62 208.5 0.0 1.5e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 GAK68548.1 - 6.5e-17 62.1 2.0 1e-16 61.5 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAK68548.1 - 2.2e-05 24.2 0.0 5.7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAK68548.1 - 0.00024 20.6 0.0 0.00062 19.2 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Abhydrolase_1 PF00561.15 GAK68548.1 - 0.0016 18.0 0.0 0.077 12.5 0.0 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Trypan_PARP PF05887.6 GAK68549.1 - 0.0047 16.7 11.6 0.0063 16.3 8.0 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 GAK68549.1 - 0.082 12.0 20.2 0.099 11.7 14.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neisseria_TspB PF05616.8 GAK68549.1 - 4.1 5.6 19.0 4.6 5.4 13.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Aa_trans PF01490.13 GAK68550.1 - 6.9e-24 84.0 11.4 8.5e-24 83.7 7.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MMPL PF03176.10 GAK68550.1 - 0.031 12.9 3.8 0.052 12.2 2.6 1.2 1 0 0 1 1 1 0 MMPL family YadA_stalk PF05662.9 GAK68550.1 - 0.13 12.1 0.0 0.39 10.5 0.0 1.9 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin Glyco_hydro_15 PF00723.16 GAK68551.1 - 2.1e-81 273.7 1.7 3e-81 273.2 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 FA_hydroxylase PF04116.8 GAK68552.1 - 6.7e-12 45.8 9.9 6.7e-12 45.8 6.9 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2208 PF09973.4 GAK68552.1 - 0.023 13.9 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Sod_Fe_C PF02777.13 GAK68553.1 - 6.2e-35 119.2 0.1 1.3e-34 118.2 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 GAK68553.1 - 5.9e-32 109.7 5.4 7e-32 109.5 2.3 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 GAK68553.1 - 0.038 13.2 0.1 1.1 8.4 0.0 2.2 1 1 1 2 2 2 0 AsmA-like C-terminal region N2227 PF07942.7 GAK68554.1 - 2.1e-83 279.4 0.0 2.3e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 GAK68554.1 - 0.05 13.3 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Rot1 PF10681.4 GAK68557.1 - 9e-68 227.7 3.4 1.1e-67 227.4 1.5 1.7 2 0 0 2 2 2 1 Chaperone for protein-folding within the ER, fungal Acyl-CoA_dh_M PF02770.14 GAK68558.1 - 2.2e-13 49.4 2.1 2.5e-13 49.2 0.4 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 GAK68558.1 - 2.9e-10 40.5 0.1 9.4e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 GAK68558.1 - 1.4e-07 31.7 2.8 1.1e-06 28.7 1.9 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Transaldolase PF00923.14 GAK68561.1 - 8.1e-28 97.3 0.0 1.3e-27 96.7 0.0 1.4 1 1 0 1 1 1 1 Transaldolase Pkinase PF00069.20 GAK68562.1 - 6.2e-36 123.8 0.0 1.5e-35 122.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAK68562.1 - 8.4e-24 84.0 0.0 1.5e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAK68562.1 - 0.026 14.2 0.1 1.3 8.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 GAK68562.1 - 0.095 11.6 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Topoisom_I_N PF02919.10 GAK68562.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Aa_trans PF01490.13 GAK68563.1 - 0.00093 17.7 9.8 0.0013 17.3 6.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_43 PF04616.9 GAK68564.1 - 1.3e-07 31.0 0.0 1.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PSCyt3 PF07627.6 GAK68565.1 - 2.8 7.8 10.7 2.1 8.2 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) Histone PF00125.19 GAK68566.1 - 9e-31 105.8 0.4 1.4e-30 105.2 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAK68566.1 - 5.5e-06 26.4 0.0 8.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAK68566.1 - 0.0018 18.3 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAK68566.1 - 0.0036 16.9 0.1 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 GAK68566.1 - 0.14 11.3 1.0 0.22 10.7 0.7 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Ribosomal_S15 PF00312.17 GAK68567.1 - 1.8e-17 62.8 0.6 3e-17 62.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 HTH_Tnp_1 PF01527.15 GAK68568.1 - 2.4e-20 72.2 0.1 2.7e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.1 GAK68568.1 - 1.3e-06 28.2 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 GAK68568.1 - 1.8e-05 24.1 0.0 3.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 GAK68568.1 - 0.00023 21.2 0.1 0.00027 21.0 0.0 1.3 1 1 0 1 1 1 1 Winged helix-turn helix HTH_26 PF13443.1 GAK68568.1 - 0.041 14.0 0.2 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Vps8 PF12816.2 GAK68568.1 - 0.067 12.4 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 HTH_11 PF08279.7 GAK68568.1 - 0.088 12.4 0.0 0.36 10.5 0.0 1.9 2 1 0 2 2 2 0 HTH domain ICL PF00463.16 GAK68569.1 - 2.8e-151 504.2 0.0 3.2e-151 504.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 GAK68569.1 - 3.9e-10 39.3 0.0 4.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 GAK68569.1 - 0.026 13.9 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain NUDIX_4 PF14815.1 GAK68570.1 - 7.8e-20 70.4 0.1 1.7e-19 69.2 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain EndIII_4Fe-2S PF10576.4 GAK68570.1 - 0.00035 20.6 9.4 0.00035 20.6 6.5 2.4 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III Whib PF02467.11 GAK68570.1 - 0.014 15.7 3.0 0.063 13.5 0.4 2.6 2 0 0 2 2 2 0 Transcription factor WhiB DUF2800 PF10926.3 GAK68570.1 - 0.065 12.3 2.8 0.88 8.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) Nucleoplasmin PF03066.10 GAK68572.1 - 0.11 12.0 3.7 0.12 11.8 2.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin EXS PF03124.9 GAK68572.1 - 0.12 11.3 0.3 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 EXS family PBP1_TM PF14812.1 GAK68572.1 - 0.15 12.3 8.6 0.33 11.2 5.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.6 GAK68572.1 - 0.18 10.4 1.2 0.22 10.1 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.7 GAK68572.1 - 0.42 10.2 5.1 0.68 9.5 3.6 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 GAK68572.1 - 0.63 7.8 5.0 0.68 7.7 3.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAK68572.1 - 1.8 6.5 6.1 2.1 6.2 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Stm1_N PF09598.5 GAK68572.1 - 6.4 7.5 12.5 5.3 7.8 6.0 2.2 2 0 0 2 2 2 0 Stm1 NOA36 PF06524.7 GAK68572.1 - 8.6 5.5 7.7 12 5.0 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.1 GAK68572.1 - 9.7 6.4 8.9 34 4.6 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611)