# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- APH PF01636.23 KXX72774.1 - 1.9e-05 24.7 0.3 2.5e-05 24.3 0.3 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KXX72774.1 - 0.0009 18.7 0.0 0.00093 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KXX72774.1 - 0.037 13.6 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NACHT PF05729.12 KXX72775.1 - 1.6e-10 41.1 0.0 3.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX72775.1 - 1.6e-06 28.6 0.3 4.6e-06 27.1 0.3 1.7 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KXX72775.1 - 0.013 14.8 0.3 0.032 13.5 0.1 1.7 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 KXX72775.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.23 KXX72775.1 - 0.017 15.2 0.2 0.33 11.0 0.1 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain HTH_30 PF13556.6 KXX72775.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain AAA_18 PF13238.6 KXX72775.1 - 0.022 15.3 0.0 0.055 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXX72775.1 - 0.064 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KXX72775.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX72775.1 - 0.25 11.7 0.2 0.77 10.2 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF676 PF05057.14 KXX72776.1 - 0.0044 16.6 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KXX72776.1 - 0.034 14.8 0.0 0.044 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_11 PF08241.12 KXX72778.1 - 1.1e-23 83.6 0.1 1.7e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX72778.1 - 1.4e-22 80.1 0.0 1.8e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX72778.1 - 5e-22 78.4 0.1 8.1e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX72778.1 - 2e-15 56.8 0.0 2.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXX72778.1 - 1.2e-14 54.8 0.0 1.8e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX72778.1 - 1.4e-10 41.2 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX72778.1 - 4.9e-07 29.4 0.0 7.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXX72778.1 - 5e-05 22.7 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 KXX72778.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXX72778.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KXX72778.1 - 0.0037 17.0 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KXX72778.1 - 0.0051 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 KXX72778.1 - 0.0093 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 KXX72778.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF938 PF06080.12 KXX72778.1 - 0.018 14.8 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DREV PF05219.12 KXX72778.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CheR PF01739.18 KXX72778.1 - 0.038 13.5 0.0 1.7 8.1 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.16 KXX72778.1 - 0.081 11.5 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 KXX72778.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LRV PF01816.17 KXX72778.1 - 1.2 9.7 4.8 14 6.4 0.3 2.9 2 0 0 2 2 2 0 Leucine rich repeat variant AMP-binding PF00501.28 KXX72779.1 - 2.7e-80 270.0 0.0 3.4e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX72779.1 - 4.9e-17 62.7 0.1 1.9e-16 60.8 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 KXX72780.1 - 4.5e-21 75.4 0.0 7.8e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX72780.1 - 1.6e-05 24.4 0.0 0.00023 20.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX72780.1 - 0.054 12.8 0.0 5.8 6.1 0.0 2.5 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 KXX72780.1 - 0.091 12.7 0.1 0.22 11.4 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family ENTH PF01417.20 KXX72781.1 - 8.5e-50 168.0 1.0 9.2e-50 167.9 0.1 1.5 2 0 0 2 2 2 1 ENTH domain DUF1720 PF08226.11 KXX72781.1 - 0.00044 20.6 38.5 0.00044 20.6 38.5 6.2 2 1 3 5 5 5 1 Domain of unknown function (DUF1720) ANTH PF07651.16 KXX72781.1 - 0.0024 16.9 0.0 0.0024 16.9 0.0 1.9 3 0 0 3 3 3 1 ANTH domain UIM PF02809.20 KXX72781.1 - 0.0046 16.8 1.2 0.0046 16.8 1.2 3.0 2 0 0 2 2 2 1 Ubiquitin interaction motif VHS PF00790.19 KXX72781.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF4264 PF14084.6 KXX72781.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) NUDIX-like PF09296.11 KXX72782.1 - 9.8e-18 64.7 0.1 3.7e-17 62.8 0.1 2.0 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 KXX72782.1 - 5.2e-16 58.9 0.3 1.2e-15 57.7 0.2 1.6 2 0 0 2 2 2 1 NUDIX domain zf-NADH-PPase PF09297.11 KXX72782.1 - 2.3e-08 33.6 1.0 4e-08 32.8 1.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF58 PF01882.18 KXX72782.1 - 0.076 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF58 Ribosomal_L1 PF00687.21 KXX72783.1 - 4.5e-47 160.4 0.3 5.1e-47 160.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Fungal_trans PF04082.18 KXX72785.1 - 0.062 12.3 0.6 0.11 11.5 0.6 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain B5 PF03484.15 KXX72785.1 - 0.53 10.6 3.3 0.27 11.6 0.2 2.1 2 0 0 2 2 2 0 tRNA synthetase B5 domain zinc_ribbon_4 PF13717.6 KXX72786.1 - 0.033 14.1 0.3 0.072 13.0 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Mut7-C PF01927.16 KXX72786.1 - 0.11 12.5 0.5 0.22 11.6 0.5 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain UBZ_FAAP20 PF15750.5 KXX72786.1 - 0.39 10.7 2.2 0.88 9.6 2.2 1.5 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger TRP PF06011.12 KXX72787.1 - 5.2e-147 490.0 17.1 6.5e-147 489.7 17.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXX72787.1 - 1.7e-39 135.4 2.0 2.9e-39 134.6 2.0 1.4 1 0 0 1 1 1 1 ML-like domain DUF2663 PF10864.8 KXX72787.1 - 6 7.3 6.5 8.6 6.8 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2663) Ribonucleas_3_3 PF14622.6 KXX72788.1 - 5e-10 39.6 0.0 7.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXX72788.1 - 1.4e-05 25.6 0.0 4.4e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Reductase_C PF14759.6 KXX72788.1 - 0.0044 17.6 0.0 0.0085 16.6 0.0 1.4 1 0 0 1 1 1 1 Reductase C-terminal Methyltransf_25 PF13649.6 KXX72789.1 - 1e-11 45.4 0.0 8e-10 39.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX72789.1 - 2.1e-08 34.8 0.0 1.2e-07 32.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX72789.1 - 4.2e-08 33.7 0.0 4e-06 27.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX72789.1 - 4.4e-06 26.2 0.0 2.3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXX72789.1 - 0.00024 21.0 0.0 0.00034 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX72789.1 - 0.0035 17.2 0.0 0.014 15.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXX72789.1 - 0.033 13.8 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KXX72789.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) BSP_II PF05432.11 KXX72790.1 - 0.016 14.9 13.1 0.019 14.7 13.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BD_b_sandwich PF18820.1 KXX72790.1 - 0.11 12.5 0.0 1.2 9.1 0.0 2.4 2 1 1 3 3 3 0 Bdellovibrio Beta-sandwich DUF4746 PF15928.5 KXX72790.1 - 0.23 10.8 11.5 0.29 10.5 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Radial_spoke PF04712.12 KXX72790.1 - 0.29 10.0 10.4 0.34 9.8 10.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.14 KXX72790.1 - 0.36 9.1 8.0 0.45 8.8 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KXX72790.1 - 0.44 9.8 8.7 0.72 9.1 8.7 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KXX72790.1 - 0.56 8.3 12.5 0.56 8.4 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3449 PF11931.8 KXX72790.1 - 0.64 9.8 8.3 1 9.1 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Myc_N PF01056.18 KXX72790.1 - 0.93 9.3 6.6 1.3 8.9 6.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.11 KXX72790.1 - 1 7.4 4.5 1.1 7.2 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4637 PF15470.6 KXX72790.1 - 1.7 8.3 10.1 3 7.6 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Paf1 PF03985.13 KXX72790.1 - 1.9 7.4 12.1 2.4 7.1 12.1 1.1 1 0 0 1 1 1 0 Paf1 JCAD PF15351.6 KXX72790.1 - 3.5 5.3 8.7 4.6 4.9 8.7 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease DNA_pol_phi PF04931.13 KXX72790.1 - 3.9 5.5 13.1 4.6 5.2 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KXX72790.1 - 5.1 6.1 16.6 6.4 5.8 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 KXX72790.1 - 6.6 5.8 7.7 9.1 5.4 7.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_3_Rpc31 PF11705.8 KXX72790.1 - 7.7 6.7 17.0 13 5.9 17.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 KXX72790.1 - 8.2 5.5 12.4 11 5.1 12.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EMP24_GP25L PF01105.24 KXX72791.1 - 2.3e-46 158.0 5.2 2.6e-46 157.9 5.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EssA PF10661.9 KXX72791.1 - 0.039 13.8 0.3 0.064 13.1 0.3 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA PhoD PF09423.10 KXX72792.1 - 4.1e-47 160.9 0.2 8.1e-47 159.9 0.2 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase SelP_N PF04592.14 KXX72793.1 - 1.6 8.0 9.2 3.7 6.9 9.2 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RPE65 PF03055.15 KXX72794.1 - 1e-97 328.3 0.0 1.2e-97 328.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Forkhead PF00250.18 KXX72795.1 - 3.2e-34 117.1 0.1 6.2e-34 116.1 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain TPR_12 PF13424.6 KXX72796.1 - 1.9e-32 111.4 1.3 1.3e-18 67.1 0.2 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXX72796.1 - 2.6e-27 93.9 1.2 1.5e-14 53.3 0.1 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX72796.1 - 1.7e-09 37.1 0.1 0.00014 21.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX72796.1 - 1.3e-07 31.2 0.0 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXX72796.1 - 9.7e-06 25.6 0.1 0.02 15.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX72796.1 - 1.1e-05 26.0 0.1 0.012 16.3 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX72796.1 - 1.3e-05 24.9 0.1 0.007 16.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX72796.1 - 2.8e-05 24.0 0.1 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXX72796.1 - 3.8e-05 23.3 0.3 0.036 13.7 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_3 PF07720.12 KXX72796.1 - 8.2e-05 22.5 0.2 0.0063 16.5 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX72796.1 - 0.00015 21.3 0.1 0.00015 21.2 0.1 1.0 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 KXX72796.1 - 0.00032 21.1 0.0 0.049 14.1 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX72796.1 - 0.00044 20.4 0.1 0.02 15.1 0.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KXX72796.1 - 0.0012 19.3 0.0 0.26 12.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 KXX72796.1 - 0.0026 18.0 0.2 0.052 13.8 0.0 2.1 1 1 1 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 PPR PF01535.20 KXX72796.1 - 0.0067 16.6 0.0 0.36 11.2 0.0 2.2 2 0 0 2 2 2 1 PPR repeat TPR_14 PF13428.6 KXX72796.1 - 0.0084 16.9 0.0 0.25 12.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXX72796.1 - 0.01 15.0 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1897 PF09005.10 KXX72796.1 - 0.017 14.6 0.2 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) TPR_20 PF14561.6 KXX72796.1 - 0.045 14.1 0.0 1.6 9.1 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat PS-DH PF14765.6 KXX72797.1 - 1.2e-65 221.7 0.5 1.9e-65 221.0 0.5 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX72797.1 - 8e-54 183.3 0.0 1.3e-53 182.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX72797.1 - 2.5e-30 104.9 0.0 5e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXX72797.1 - 6.9e-20 71.6 0.0 1.8e-19 70.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain ketoacyl-synt PF00109.26 KXX72797.1 - 8.9e-20 71.3 0.7 1.9e-19 70.2 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 KXX72797.1 - 4.9e-19 68.8 0.0 1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXX72797.1 - 8e-16 58.5 0.0 2.5e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX72797.1 - 1.7e-13 51.0 0.0 5.1e-13 49.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX72797.1 - 2.6e-11 43.5 0.0 5.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX72797.1 - 1.4e-10 41.2 0.0 3.9e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KXX72797.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) ACP_syn_III PF08545.10 KXX72797.1 - 0.0012 18.7 0.1 0.0049 16.7 0.1 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF938 PF06080.12 KXX72797.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 KXX72797.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KXX72797.1 - 0.0097 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KXX72797.1 - 0.036 15.1 0.0 0.11 13.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain HET PF06985.11 KXX72798.1 - 2.9e-05 24.5 0.0 3.7e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 KXX72799.1 - 9.8e-29 100.6 0.1 1.3e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX72799.1 - 6.1e-18 65.4 0.0 8.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX72799.1 - 6.5e-05 22.5 0.2 0.00017 21.1 0.0 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX72799.1 - 0.0049 15.9 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HMGL-like PF00682.19 KXX72800.1 - 3.8e-81 272.5 0.0 6.2e-81 271.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KXX72800.1 - 3.2e-24 85.3 0.0 1.2e-23 83.5 0.0 2.0 2 1 0 2 2 2 1 LeuA allosteric (dimerisation) domain TMCO5 PF14992.6 KXX72802.1 - 0.015 14.9 3.9 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 TMCO5 family DUF2046 PF09755.9 KXX72802.1 - 0.023 13.9 2.3 0.025 13.8 0.9 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) APG6_N PF17675.1 KXX72802.1 - 0.077 13.5 2.4 2.2 8.8 0.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF1192 PF06698.11 KXX72802.1 - 0.14 12.2 0.3 0.42 10.7 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) KASH_CCD PF14662.6 KXX72802.1 - 0.2 11.4 5.4 5.1 6.9 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 KXX72802.1 - 0.21 12.2 6.3 5.4 7.7 2.3 2.4 2 0 0 2 2 2 0 SlyX K-box PF01486.17 KXX72802.1 - 0.22 11.7 6.6 6.8 7.0 1.7 2.4 2 0 0 2 2 2 0 K-box region Shugoshin_N PF07558.11 KXX72802.1 - 0.35 10.8 0.1 0.35 10.8 0.1 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 KXX72802.1 - 0.36 10.6 4.4 4.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 KXX72802.1 - 0.36 11.3 9.3 1.7 9.1 0.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB HAP1_N PF04849.13 KXX72802.1 - 1.3 8.1 7.3 0.22 10.7 0.4 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DAO PF01266.24 KXX72803.1 - 5.5e-62 210.4 3.3 6.4e-62 210.2 3.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX72803.1 - 2.2e-05 24.6 1.6 4.9e-05 23.5 1.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX72803.1 - 0.021 14.1 0.2 0.045 13.0 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX72803.1 - 0.023 15.3 0.1 0.074 13.6 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX72803.1 - 0.034 13.4 0.6 0.14 11.3 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KXX72803.1 - 0.32 10.3 3.0 2 7.7 3.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase ELFV_dehydrog PF00208.21 KXX72804.1 - 1.5e-66 224.6 0.0 2.4e-66 223.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KXX72804.1 - 1.5e-18 65.9 0.0 1.4e-13 49.4 0.0 2.4 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KXX72804.1 - 0.0043 16.9 0.0 0.039 13.8 0.0 2.4 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Spore_III_AB PF09548.10 KXX72804.1 - 0.22 11.6 0.0 0.47 10.5 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FAD_binding_4 PF01565.23 KXX72805.1 - 7e-25 87.4 2.2 1.5e-24 86.3 2.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX72805.1 - 1.2e-13 50.9 0.1 3e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KXX72806.1 - 1.8e-61 208.3 0.0 2.2e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KXX72807.1 - 2.8e-09 36.9 12.4 0.0084 16.5 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX72807.1 - 0.00032 21.3 8.6 1.1 10.2 1.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KXX72807.1 - 9.6 6.6 6.4 3.6 7.9 1.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SPX PF03105.19 KXX72808.1 - 1.1 9.2 8.7 1.2 9.0 8.7 1.0 1 0 0 1 1 1 0 SPX domain PIG-X PF08320.12 KXX72809.1 - 1.1e-69 234.6 0.0 1.9e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 Homeodomain PF00046.29 KXX72810.1 - 1.3e-09 37.7 0.3 7.9e-09 35.2 0.0 2.4 2 0 0 2 2 2 1 Homeodomain Rhodanese PF00581.20 KXX72810.1 - 7.5e-07 29.6 0.0 2.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DUF5390 PF17365.2 KXX72810.1 - 0.28 11.4 1.9 0.32 11.3 0.1 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF5390) DUF4611 PF15387.6 KXX72811.1 - 0.0075 16.5 14.2 0.55 10.5 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) PI3K_1B_p101 PF10486.9 KXX72811.1 - 0.42 8.3 1.8 0.65 7.7 1.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GP67 PF17634.2 KXX72811.1 - 0.67 10.4 13.4 2.5 8.6 13.4 2.0 1 0 0 1 1 1 0 Gene product 67 FAM176 PF14851.6 KXX72811.1 - 0.97 9.1 4.0 3.4 7.3 4.0 1.9 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 KXX72811.1 - 1.1 9.0 11.1 0.42 10.3 6.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KXX72811.1 - 2.2 6.4 5.9 3.3 5.8 5.9 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KXX72811.1 - 4.7 5.2 11.1 7.7 4.5 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 KXX72811.1 - 4.7 6.3 8.3 8.5 5.4 8.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pox_Ag35 PF03286.14 KXX72811.1 - 5.8 6.6 7.9 1.3 8.8 3.4 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 KXX72812.1 - 0.07 13.4 6.8 0.22 11.8 6.8 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 KXX72812.1 - 0.24 11.2 2.7 0.61 9.8 2.7 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PI3K_1B_p101 PF10486.9 KXX72812.1 - 0.39 8.4 1.8 0.59 7.8 1.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4611 PF15387.6 KXX72812.1 - 0.5 10.6 0.0 0.5 10.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 KXX72812.1 - 0.67 9.6 7.7 1.3 8.7 7.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 KXX72812.1 - 1.3 8.7 4.4 4 7.1 4.4 1.8 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 KXX72812.1 - 2.2 6.4 5.7 3.3 5.8 5.7 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KXX72812.1 - 4.3 5.3 11.1 7.1 4.6 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_S15 PF00312.22 KXX72815.1 - 1.2e-21 76.7 1.2 2.2e-21 75.8 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.16 KXX72816.1 - 3.3e-109 365.5 0.0 3.6e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S2 PF00318.20 KXX72817.1 - 1.2e-22 80.3 0.2 2e-15 56.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KXX72817.1 - 7.8e-05 24.0 14.7 0.00014 23.2 14.7 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus 2OG-FeII_Oxy_2 PF13532.6 KXX72819.1 - 0.0086 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP12 PF07542.11 KXX72820.1 - 6.6e-41 139.4 0.0 1.1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein JAB PF01398.21 KXX72821.1 - 6.2e-13 48.8 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KXX72821.1 - 5.3e-05 23.0 0.1 0.00015 21.5 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 KXX72821.1 - 0.00076 19.6 1.6 0.001 19.3 0.0 2.0 3 0 0 3 3 3 1 USP8 dimerisation domain Beta-lactamase PF00144.24 KXX72823.1 - 6.5e-35 120.9 0.0 1.4e-34 119.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXX72823.1 - 0.17 12.3 0.1 33 5.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) Prefoldin_2 PF01920.20 KXX72824.1 - 1.7e-22 79.4 10.6 2.1e-22 79.1 10.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit MIP-T3_C PF17749.1 KXX72824.1 - 0.0029 17.6 1.0 0.0029 17.6 1.0 2.2 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Prefoldin PF02996.17 KXX72824.1 - 0.0032 17.4 9.2 0.0065 16.4 0.5 2.2 2 0 0 2 2 2 1 Prefoldin subunit DUF5446 PF17522.2 KXX72824.1 - 0.0069 16.5 1.3 0.25 11.5 0.0 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5446) Spc7 PF08317.11 KXX72824.1 - 0.016 14.1 10.6 0.021 13.7 10.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Prefoldin_3 PF13758.6 KXX72824.1 - 0.017 15.2 2.6 0.022 14.8 2.6 1.2 1 0 0 1 1 1 0 Prefoldin subunit DivIC PF04977.15 KXX72824.1 - 0.019 14.7 15.0 1.3 8.9 0.5 3.1 2 1 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 KXX72824.1 - 0.019 15.2 8.8 0.31 11.3 2.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1732 PF08340.11 KXX72824.1 - 0.026 14.5 0.7 0.27 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) DUF5082 PF16888.5 KXX72824.1 - 0.026 14.8 0.3 0.026 14.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) GAS PF13851.6 KXX72824.1 - 0.073 12.4 12.6 0.24 10.7 12.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KXX72824.1 - 0.094 13.2 8.3 0.62 10.5 0.9 2.1 2 0 0 2 2 2 0 Fez1 BORCS8 PF10167.9 KXX72824.1 - 0.13 12.2 3.5 0.67 9.9 0.7 2.1 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 ERp29 PF07749.12 KXX72824.1 - 0.14 13.1 5.8 1.2 10.1 5.8 2.1 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain ABC_tran_CTD PF16326.5 KXX72824.1 - 0.14 12.4 8.0 1.7 8.9 0.3 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain Occludin_ELL PF07303.13 KXX72824.1 - 0.15 12.8 5.6 0.18 12.5 2.0 2.0 2 0 0 2 2 2 0 Occludin homology domain BRE1 PF08647.11 KXX72824.1 - 0.17 12.0 11.5 1.5 8.9 0.5 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.12 KXX72824.1 - 0.56 10.7 4.1 1.9 9.0 2.5 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 KXX72824.1 - 0.59 10.3 13.4 3.1 8.0 6.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Tektin PF03148.14 KXX72824.1 - 0.65 8.7 8.9 2.2 6.9 1.9 2.0 2 0 0 2 2 2 0 Tektin family FlaC_arch PF05377.11 KXX72824.1 - 0.68 10.4 6.0 17 5.9 0.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) PHM7_cyt PF14703.6 KXX72824.1 - 0.78 10.0 6.6 2.1 8.6 6.6 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Sas10_Utp3 PF04000.15 KXX72824.1 - 0.84 10.3 4.5 11 6.7 1.0 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DUF2408 PF10303.9 KXX72824.1 - 0.96 10.0 7.6 1.7 9.2 7.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Siah-Interact_N PF09032.11 KXX72824.1 - 1.5 9.2 9.9 4.3 7.7 2.6 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal Uso1_p115_C PF04871.13 KXX72824.1 - 1.8 8.9 12.7 2 8.8 4.9 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 KXX72824.1 - 1.8 8.6 6.6 5.7 7.0 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Com_YlbF PF06133.11 KXX72824.1 - 2.3 8.9 13.7 0.77 10.4 6.5 2.4 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA YabA PF06156.13 KXX72824.1 - 2.7 8.7 7.4 4.7 7.9 3.0 2.1 1 1 0 2 2 2 0 Initiation control protein YabA Cep57_MT_bd PF06657.13 KXX72824.1 - 2.8 8.4 9.2 7.1 7.2 0.6 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 OmpH PF03938.14 KXX72824.1 - 3.3 8.0 19.1 3.2e+02 1.6 19.1 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LPP PF04728.13 KXX72824.1 - 4.6 7.7 8.9 9.4 6.7 0.6 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4140 PF13600.6 KXX72824.1 - 6.5 7.3 8.1 21 5.7 2.9 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KXX72824.1 - 7.1 7.2 15.4 8.1 7.0 7.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 KXX72824.1 - 8.7 6.4 15.2 7.7 6.6 3.6 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HET PF06985.11 KXX72825.1 - 1.7e-29 103.0 0.0 3.2e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RPN7 PF10602.9 KXX72827.1 - 0.018 14.8 0.2 0.032 13.9 0.1 1.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 BTB PF00651.31 KXX72829.1 - 0.0012 19.1 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HSP70 PF00012.20 KXX72831.1 - 0.0042 15.3 0.0 0.0042 15.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXX72831.1 - 0.017 14.0 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Pectinesterase PF01095.19 KXX72831.1 - 0.03 13.1 0.1 0.035 12.8 0.1 1.1 1 0 0 1 1 1 0 Pectinesterase AIG1 PF04548.16 KXX72832.1 - 0.098 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family RSN1_7TM PF02714.15 KXX72833.1 - 2.8e-80 269.6 25.4 2.8e-80 269.6 25.4 2.5 4 0 0 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXX72833.1 - 7.7e-40 136.2 0.6 7.7e-40 136.2 0.6 3.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXX72833.1 - 2e-28 99.8 0.1 2e-16 60.7 0.2 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXX72833.1 - 7.9e-15 54.8 0.0 2.2e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter NRho PF16733.5 KXX72833.1 - 0.035 14.2 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 Rhomboid N-terminal domain FAD_binding_3 PF01494.19 KXX72834.1 - 3.4e-18 66.0 0.2 3.3e-17 62.7 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX72834.1 - 3.1e-06 27.3 0.4 6.7e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX72834.1 - 4.7e-06 26.0 0.5 0.018 14.3 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXX72834.1 - 0.0001 21.4 0.0 0.00038 19.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KXX72834.1 - 0.00024 20.8 1.2 0.0017 18.0 1.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX72834.1 - 0.0099 16.4 0.2 0.045 14.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX72834.1 - 0.011 14.8 0.4 0.029 13.5 0.5 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KXX72834.1 - 0.012 14.9 0.2 0.15 11.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXX72834.1 - 0.11 11.8 0.2 0.25 10.6 0.2 1.6 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.17 KXX72834.1 - 0.18 11.0 0.2 0.35 10.1 0.2 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KXX72834.1 - 0.31 10.1 0.9 0.46 9.5 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 KXX72836.1 - 9.7e-34 116.8 45.5 9.7e-34 116.8 45.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KXX72836.1 - 4.7e-06 25.6 0.3 4.7e-06 25.6 0.3 1.8 2 0 0 2 2 2 1 LacY proton/sugar symporter HET PF06985.11 KXX72837.1 - 7.8e-18 65.2 1.3 1.4e-17 64.4 1.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HLH PF00010.26 KXX72838.1 - 3e-10 39.9 0.0 1.1e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 KXX72839.1 - 1.4e-12 47.4 0.0 1.4e-12 47.4 0.0 1.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 KXX72839.1 - 0.033 14.4 0.7 0.23 11.7 0.1 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ret2_MD PF18528.1 KXX72839.1 - 0.12 12.8 0.7 0.33 11.4 0.3 1.8 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain RRXRR PF14239.6 KXX72839.1 - 0.27 11.1 5.8 0.47 10.3 0.7 2.1 2 0 0 2 2 2 0 RRXRR protein RSN1_7TM PF02714.15 KXX72840.1 - 4.4e-90 301.7 27.3 4.4e-90 301.7 27.3 2.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXX72840.1 - 5.3e-46 156.2 1.1 5.3e-46 156.2 1.1 3.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXX72840.1 - 9.5e-38 130.2 0.0 1.5e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXX72840.1 - 4.3e-28 97.3 0.1 1.6e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter MAGI_u1 PF16663.5 KXX72840.1 - 0.0041 17.2 0.5 0.0077 16.3 0.5 1.4 1 0 0 1 1 1 1 Unstructured region on MAGI EF-hand_5 PF13202.6 KXX72840.1 - 0.17 11.4 0.1 0.37 10.4 0.1 1.5 1 0 0 1 1 1 0 EF hand Kelch_6 PF13964.6 KXX72841.1 - 0.0017 18.6 6.1 2.7 8.4 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KXX72841.1 - 0.0042 17.0 3.0 6.4 6.9 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KXX72841.1 - 2.7 8.1 7.2 18 5.5 0.2 4.3 4 1 0 4 4 4 0 Galactose oxidase, central domain Mto2_bdg PF12808.7 KXX72842.1 - 2.7 8.3 8.9 0.58 10.5 0.6 3.1 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.15 KXX72842.1 - 3.1 7.9 8.9 3 8.0 0.8 2.5 1 1 1 2 2 2 0 Basic region leucine zipper OrsD PF12013.8 KXX72843.1 - 3.6e-09 37.1 0.0 6.4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D CENP-B_dimeris PF09026.10 KXX72843.1 - 1.3 9.5 15.7 0.25 11.8 3.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DEAD PF00270.29 KXX72844.1 - 0.00032 20.5 0.0 0.55 10.0 0.0 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase GLEYA PF10528.9 KXX72845.1 - 9.1e-15 54.9 0.1 1.9e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 GLEYA domain Drf_FH1 PF06346.12 KXX72845.1 - 0.15 11.8 8.2 0.24 11.1 8.2 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 Peptidase_M27 PF01742.17 KXX72845.1 - 0.26 10.4 0.3 0.5 9.4 0.1 1.5 2 0 0 2 2 2 0 Clostridial neurotoxin zinc protease zf-RING_2 PF13639.6 KXX72847.1 - 3.6e-11 43.2 3.3 7.9e-11 42.1 3.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXX72847.1 - 1.4e-08 34.9 2.5 1.4e-08 34.9 2.5 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXX72847.1 - 1.9e-06 27.8 0.5 4e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KXX72847.1 - 1.4e-05 25.0 1.8 1.4e-05 25.0 1.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXX72847.1 - 5.2e-05 23.0 1.5 0.00011 22.0 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXX72847.1 - 9.3e-05 22.2 3.4 0.00018 21.3 3.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXX72847.1 - 0.0001 22.1 5.6 0.00034 20.4 5.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX72847.1 - 0.00018 21.3 2.4 0.00031 20.5 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX72847.1 - 0.0022 18.0 4.5 0.0055 16.7 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXX72847.1 - 0.012 15.4 0.6 0.039 13.7 0.6 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 KXX72847.1 - 0.013 15.4 0.2 0.028 14.3 0.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 KXX72847.1 - 0.018 14.7 0.6 0.018 14.7 0.6 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KXX72847.1 - 0.02 15.1 3.3 0.51 10.6 3.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain IF4E PF01652.18 KXX72849.1 - 5.1e-38 130.4 0.3 6.8e-38 130.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NPV_P10 PF05531.12 KXX72851.1 - 0.13 12.8 1.1 6.7 7.3 1.1 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Form_Nir_trans PF01226.17 KXX72852.1 - 6.1e-66 222.1 14.9 8.1e-66 221.7 14.9 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter Spore_YtrH PF14034.6 KXX72852.1 - 0.028 14.6 0.4 0.57 10.4 0.0 2.5 2 1 0 2 2 2 0 Sporulation protein YtrH PIRT PF15099.6 KXX72852.1 - 0.2 11.3 3.3 0.15 11.6 0.4 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Cu-oxidase_3 PF07732.15 KXX72853.1 - 8.1e-14 51.7 0.1 2.1e-09 37.4 0.1 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXX72853.1 - 1.4e-13 50.7 0.0 2e-05 24.3 0.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXX72853.1 - 2.8e-05 24.1 0.0 0.018 15.2 0.0 2.3 2 0 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.20 KXX72853.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family HLH PF00010.26 KXX72854.1 - 5.9e-12 45.4 0.8 5.9e-12 45.4 0.8 3.0 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 KXX72854.1 - 0.0033 16.5 1.5 0.0047 16.0 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) MnmE_helical PF12631.7 KXX72854.1 - 0.0058 16.8 1.8 0.01 16.0 1.8 1.3 1 0 0 1 1 1 1 MnmE helical domain SlyX PF04102.12 KXX72854.1 - 0.01 16.5 6.3 0.021 15.4 1.2 2.9 1 1 0 2 2 2 0 SlyX Phage_GPO PF05929.11 KXX72854.1 - 0.011 15.4 1.2 0.018 14.7 1.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Taxilin PF09728.9 KXX72854.1 - 0.014 14.6 5.6 0.02 14.1 5.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Fib_alpha PF08702.10 KXX72854.1 - 0.027 14.6 6.3 0.064 13.4 5.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KXX72854.1 - 0.037 14.3 2.0 0.037 14.3 2.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) HeLo PF14479.6 KXX72854.1 - 0.039 13.8 1.8 0.068 13.0 1.8 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF641 PF04859.12 KXX72854.1 - 0.076 13.3 5.3 0.15 12.4 5.0 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 KXX72854.1 - 0.11 12.6 4.6 0.06 13.4 2.2 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.16 KXX72854.1 - 0.14 12.3 5.9 0.48 10.7 5.9 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein DUF745 PF05335.13 KXX72854.1 - 0.17 11.6 2.3 0.32 10.7 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KXX72854.1 - 0.17 11.9 0.8 0.28 11.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MetOD2 PF18548.1 KXX72854.1 - 0.21 11.7 1.3 0.47 10.6 1.3 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 DivIC PF04977.15 KXX72854.1 - 0.21 11.3 0.1 0.21 11.3 0.1 1.6 2 0 0 2 2 1 0 Septum formation initiator Golgin_A5 PF09787.9 KXX72854.1 - 0.26 10.7 9.3 0.41 10.1 9.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 YabA PF06156.13 KXX72854.1 - 0.3 11.7 1.6 0.56 10.9 0.6 1.8 1 1 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 KXX72854.1 - 0.64 10.1 7.3 0.73 9.9 6.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KXX72854.1 - 1.1 9.0 5.4 1.9 8.3 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 KXX72854.1 - 1.2 9.2 8.3 2.4 8.2 8.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 KXX72854.1 - 1.4 8.9 5.3 0.34 10.9 1.5 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 KXX72854.1 - 2.1 7.7 6.2 3.3 7.0 6.2 1.2 1 0 0 1 1 1 0 FAM76 protein Hydrolase_6 PF13344.6 KXX72855.1 - 1.3e-29 102.3 0.0 2.3e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX72855.1 - 6.9e-15 55.9 0.0 1.7e-07 31.7 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXX72855.1 - 1.4e-14 53.9 0.0 5.6e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 KXX72855.1 - 5e-06 26.7 0.0 0.059 13.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KXX72855.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) SET PF00856.28 KXX72856.1 - 1.5e-09 38.5 0.0 3.4e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.16 KXX72858.1 - 1.7e-31 109.5 32.9 2.1e-31 109.1 32.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX72858.1 - 2e-19 69.5 15.5 2.3e-19 69.3 15.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX72858.1 - 3.1e-11 42.8 14.0 3.1e-11 42.8 14.0 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 KXX72860.1 - 9.4e-28 97.2 0.4 6.8e-15 54.8 0.1 2.2 1 1 1 2 2 2 2 Cytochrome P450 DUF4938 PF16292.5 KXX72860.1 - 0.064 12.5 0.2 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4938) p450 PF00067.22 KXX72861.1 - 3.1e-43 148.2 0.0 4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KXX72862.1 - 1.6e-10 41.1 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX72862.1 - 0.0027 18.8 0.0 0.0059 17.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX72862.1 - 0.0036 17.2 0.3 0.03 14.2 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TPR_12 PF13424.6 KXX72863.1 - 2.2e-24 85.6 8.0 8.2e-18 64.5 2.2 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXX72863.1 - 9.5e-23 79.4 2.7 1.2e-11 44.1 0.2 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX72863.1 - 2.3e-06 27.2 0.3 0.071 13.0 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX72863.1 - 7.2e-05 22.6 1.4 0.3 11.3 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX72863.1 - 7.2e-05 23.4 0.1 0.064 13.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KXX72863.1 - 0.00018 21.4 0.5 0.57 10.2 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4763 PF15960.5 KXX72863.1 - 0.00026 20.4 4.0 0.00031 20.1 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) ANAPC3 PF12895.7 KXX72863.1 - 0.0013 18.9 0.2 1.2 9.4 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXX72863.1 - 0.0018 18.2 3.2 0.61 10.2 0.3 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXX72863.1 - 0.008 16.5 0.2 2.7 8.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX72863.1 - 0.0097 16.1 0.4 4 7.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Melibiase_2_C PF17450.2 KXX72863.1 - 0.032 14.5 0.0 6.6 7.0 0.0 2.0 1 1 1 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain kleA_kleC PF17383.2 KXX72863.1 - 0.04 14.2 4.4 2.1 8.7 0.3 2.1 1 1 0 2 2 2 0 Uncharacterized KorC regulated protein A NYD-SP28_assoc PF14775.6 KXX72863.1 - 0.12 12.5 8.8 2.2 8.5 1.2 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain PspB PF06667.12 KXX72863.1 - 0.22 11.6 3.6 3 7.9 0.4 2.1 2 0 0 2 2 2 0 Phage shock protein B DUF2680 PF10925.8 KXX72863.1 - 0.86 9.7 5.4 7.8 6.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) T2SSppdC PF12528.8 KXX72863.1 - 1.8 9.4 6.8 11 6.8 0.6 2.0 1 1 1 2 2 2 0 Type II secretion prepilin peptidase dependent protein C DUF4187 PF13821.6 KXX72863.1 - 2.7 7.8 5.7 16 5.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Nop10p PF04135.12 KXX72866.1 - 4e-19 68.4 0.1 4.5e-19 68.2 0.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Bys1 PF04681.12 KXX72868.1 - 3.8e-14 52.9 0.0 4.3e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NOB1_Zn_bind PF08772.11 KXX72869.1 - 3.8e-32 110.3 4.4 6.5e-32 109.5 4.4 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KXX72869.1 - 5.4e-32 110.1 0.6 1.4e-31 108.8 0.2 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease DNA_ligase_A_C PF04679.15 KXX72869.1 - 0.073 13.7 0.1 3.3 8.4 0.0 2.3 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region HypA PF01155.19 KXX72869.1 - 0.14 12.2 0.5 0.28 11.2 0.5 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WRNPLPNID PF15017.6 KXX72869.1 - 0.34 11.8 3.3 0.97 10.3 3.3 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box zf-NADH-PPase PF09297.11 KXX72869.1 - 0.52 10.0 6.9 0.26 11.0 1.0 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Tannase PF07519.11 KXX72870.1 - 1.5e-97 327.5 0.0 6.1e-97 325.5 0.0 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase DUF4350 PF14258.6 KXX72870.1 - 0.086 13.3 0.1 5.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) CLIP_SPH_mas PF18398.1 KXX72870.1 - 0.13 12.7 0.5 0.27 11.7 0.5 1.5 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade MFS_1 PF07690.16 KXX72871.1 - 2.7e-29 102.2 29.7 2.7e-29 102.2 29.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily CTP_synth_N PF06418.14 KXX72872.1 - 1e-118 395.5 0.0 1.3e-118 395.1 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KXX72872.1 - 1.7e-53 181.2 0.0 2.8e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXX72872.1 - 9.6e-05 22.2 0.0 0.00047 20.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 RVT_connect PF06815.13 KXX72872.1 - 0.097 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase connection domain Ank_2 PF12796.7 KXX72873.1 - 2.7e-37 127.2 0.0 2.7e-11 43.9 0.0 4.6 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXX72873.1 - 9.9e-31 104.8 3.0 0.00044 20.6 0.0 8.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 KXX72873.1 - 1.6e-29 101.9 0.0 8.4e-06 26.2 0.0 5.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX72873.1 - 1e-25 86.9 1.4 0.0027 18.0 0.0 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KXX72873.1 - 2.6e-25 88.2 2.6 2.2e-05 24.6 0.0 6.4 3 1 2 6 6 6 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KXX72876.1 - 0.00056 19.2 2.9 0.0036 16.6 2.9 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily ssDNA_TraI_N PF18272.1 KXX72876.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain NACHT PF05729.12 KXX72877.1 - 0.0078 16.1 0.1 0.021 14.8 0.1 1.7 1 1 1 2 2 2 1 NACHT domain RRM_1 PF00076.22 KXX72878.1 - 1.1e-09 37.9 0.1 2.6e-07 30.4 0.1 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.11 KXX72878.1 - 4.1 6.7 8.8 0.31 10.4 3.1 1.8 1 1 1 2 2 2 0 AAR2 protein Aldedh PF00171.22 KXX72879.1 - 4.8e-132 440.8 0.0 5.3e-132 440.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXX72879.1 - 1e-06 28.1 0.0 2.6e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) TPR_1 PF00515.28 KXX72881.1 - 7.4e-10 38.2 0.5 0.00095 18.9 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX72881.1 - 5.2e-09 36.3 2.0 1e-06 28.9 0.8 2.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX72881.1 - 5.5e-09 35.5 1.5 0.00062 19.7 0.1 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXX72881.1 - 1e-08 34.7 1.0 3.3e-06 26.7 0.2 3.1 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 KXX72881.1 - 9.9e-06 25.2 3.1 0.23 11.6 0.0 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX72881.1 - 0.00096 19.6 1.1 0.013 16.0 1.1 2.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX72881.1 - 0.0019 18.8 4.8 0.11 13.2 0.2 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX72881.1 - 0.0037 18.0 5.4 0.14 13.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX72881.1 - 0.0076 16.4 3.0 0.029 14.6 2.5 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXX72881.1 - 0.02 15.5 1.8 20 6.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX72881.1 - 0.028 14.3 6.1 3.3 7.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Aida_N PF08910.10 KXX72881.1 - 0.043 14.2 1.9 9.3 6.7 0.1 2.9 2 1 0 2 2 2 0 Aida N-terminus TPR_8 PF13181.6 KXX72881.1 - 0.095 13.0 0.6 5.7 7.4 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4295 PF14128.6 KXX72881.1 - 0.11 12.4 0.6 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) MIT PF04212.18 KXX72881.1 - 0.15 12.2 6.1 1.1 9.4 0.3 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain NMD3 PF04981.13 KXX72882.1 - 7.3e-78 261.4 1.8 1.1e-77 260.9 1.8 1.2 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 KXX72882.1 - 0.25 11.4 2.0 7.6 6.6 0.3 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KXX72882.1 - 0.46 10.6 3.8 1.8 8.6 2.6 2.3 2 1 0 2 2 2 0 Double zinc ribbon Peptidase_S8 PF00082.22 KXX72883.1 - 2e-12 47.0 1.4 2.5e-12 46.7 1.4 1.1 1 0 0 1 1 1 1 Subtilase family zf-C2H2_4 PF13894.6 KXX72885.1 - 3.8e-05 24.2 11.2 0.79 10.7 1.0 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KXX72885.1 - 0.39 11.2 7.8 0.26 11.8 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXX72885.1 - 0.48 10.8 5.8 1.2 9.5 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KXX72885.1 - 2.2 8.9 7.4 0.6 10.6 0.7 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 KXX72885.1 - 4.7 7.9 10.4 5.5 7.7 0.5 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Fungal_trans PF04082.18 KXX72886.1 - 1.2e-20 73.7 0.7 1.2e-20 73.7 0.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX72886.1 - 1.1e-07 31.8 12.7 2.1e-07 30.9 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KXX72887.1 - 4.4e-104 348.6 0.0 3.1e-103 345.8 0.0 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family PhoLip_ATPase_C PF16212.5 KXX72888.1 - 1.1e-75 254.6 26.7 1.1e-75 254.6 26.7 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXX72888.1 - 3.5e-20 71.4 1.3 8.2e-20 70.3 1.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXX72888.1 - 6.6e-14 51.8 0.0 3.1e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX72888.1 - 1e-12 48.8 3.2 2.7e-09 37.7 0.8 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXX72888.1 - 0.00016 21.3 0.3 0.0027 17.3 0.0 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXX72888.1 - 0.012 15.3 0.6 0.026 14.3 0.6 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.32 KXX72889.1 - 1.7e-22 79.3 4.6 5.6e-11 42.8 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX72889.1 - 1.5e-05 25.2 0.0 0.0002 21.6 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Invasin_D3 PF09134.10 KXX72889.1 - 0.00026 21.2 4.4 0.16 12.3 0.4 2.4 1 1 1 2 2 2 2 Invasin, domain 3 DUF642 PF04862.12 KXX72889.1 - 0.0099 15.7 0.2 0.09 12.6 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF642) Big_5 PF13205.6 KXX72889.1 - 0.012 16.3 0.7 1.1 9.9 0.3 2.0 1 1 1 2 2 2 0 Bacterial Ig-like domain DUF1216 PF06746.11 KXX72889.1 - 0.013 15.5 0.0 1.2 9.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) WD40_like PF17005.5 KXX72889.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.4 1 1 1 2 2 2 0 WD40-like domain dsrm PF00035.26 KXX72889.1 - 0.066 13.9 0.4 3.9 8.2 0.1 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding motif LXG PF04740.12 KXX72889.1 - 0.085 12.6 0.0 2 8.1 0.0 1.9 1 1 1 2 2 2 0 LXG domain of WXG superfamily Ge1_WD40 PF16529.5 KXX72889.1 - 0.12 11.4 0.1 1.7 7.6 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HATPase_c PF02518.26 KXX72890.1 - 8.2e-27 93.9 0.2 8.2e-27 93.9 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXX72890.1 - 7.3e-22 77.6 0.0 1.6e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 KXX72890.1 - 1.4e-20 73.3 0.4 1.6e-11 44.3 0.2 3.7 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 KXX72890.1 - 2.6e-20 72.2 0.1 6.3e-20 71.0 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KXX72890.1 - 1.4e-08 34.9 0.0 0.013 15.7 0.0 4.3 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 KXX72890.1 - 5.2e-07 29.6 0.0 0.033 14.2 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KXX72890.1 - 2e-06 28.0 0.5 7.2e-05 23.0 0.1 2.9 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 KXX72890.1 - 0.00046 20.1 0.0 0.28 11.3 0.0 2.6 2 0 0 2 2 2 2 PAS domain 2-Hacid_dh_C PF02826.19 KXX72891.1 - 4.4e-54 182.5 0.0 6.4e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXX72891.1 - 8.8e-35 119.3 0.2 1.1e-34 119.0 0.2 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 KXX72891.1 - 0.0044 17.5 0.0 0.0096 16.4 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 KXX72891.1 - 0.027 14.5 0.3 0.057 13.5 0.1 1.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF21 PF01595.20 KXX72892.1 - 7.9e-33 113.6 0.0 2.3e-32 112.1 0.0 1.8 2 1 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXX72892.1 - 7e-05 23.2 0.2 0.017 15.6 0.0 3.3 3 0 0 3 3 3 2 CBS domain Glyoxalase PF00903.25 KXX72893.1 - 1.2e-40 138.6 0.0 5.1e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXX72893.1 - 8.2e-17 61.5 0.0 1.9e-06 28.1 0.0 4.1 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXX72893.1 - 6.1e-08 33.4 0.0 0.00046 20.9 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KXX72893.1 - 1.3e-05 25.1 0.4 0.3 11.0 0.0 4.0 4 0 0 4 4 4 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KXX72893.1 - 4.3e-05 23.7 0.0 0.6 10.2 0.0 3.3 2 1 1 3 3 3 2 Glyoxalase-like domain MoaF PF10703.9 KXX72893.1 - 0.019 14.9 0.1 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 MoaF N-terminal domain CppA_N PF14506.6 KXX72893.1 - 0.044 13.9 0.0 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal DUF1338 PF07063.13 KXX72893.1 - 0.065 12.4 0.0 55 2.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1338) Tyrosinase PF00264.20 KXX72895.1 - 1.3e-50 172.7 0.7 1.3e-50 172.7 0.7 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXX72895.1 - 1.2e-33 116.4 0.0 1.9e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain DUF4424 PF14415.6 KXX72895.1 - 0.046 13.0 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) Ser_hydrolase PF06821.13 KXX72895.1 - 0.089 12.6 0.9 0.41 10.5 0.9 2.0 1 1 0 1 1 1 0 Serine hydrolase BtrH_N PF14399.6 KXX72896.1 - 5.7e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Butirosin biosynthesis protein H, N-terminal Peptidase_C39 PF03412.15 KXX72896.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family Erv26 PF04148.13 KXX72897.1 - 3.5e-96 320.9 0.1 3.9e-96 320.8 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.8 KXX72897.1 - 0.017 15.0 0.2 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) TMEM43 PF07787.12 KXX72897.1 - 0.33 10.3 3.1 0.53 9.6 3.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 WBS_methylT PF12589.8 KXX72898.1 - 4.6e-14 52.9 5.0 8.3e-14 52.1 5.0 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KXX72898.1 - 4.5e-11 43.2 0.0 8.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX72898.1 - 1.5e-09 38.5 0.0 3.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXX72898.1 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KXX72898.1 - 0.00018 22.2 0.0 0.00055 20.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX72898.1 - 0.00092 19.0 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXX72898.1 - 0.0029 17.0 0.0 0.028 13.7 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXX72898.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXX72898.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.21 KXX72899.1 - 4e-24 85.3 0.0 5.5e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sds3 PF08598.11 KXX72900.1 - 0.052 13.5 1.0 0.1 12.6 1.0 1.4 1 0 0 1 1 1 0 Sds3-like Rad60-SLD PF11976.8 KXX72900.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NOA36 PF06524.12 KXX72901.1 - 0.016 14.5 9.8 0.026 13.8 9.8 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KXX72901.1 - 0.03 13.8 5.2 0.046 13.1 5.2 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KXX72901.1 - 0.076 11.1 11.7 0.1 10.6 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KXX72901.1 - 0.09 11.1 6.0 0.14 10.4 6.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Cucumo_2B PF03263.13 KXX72901.1 - 0.15 12.5 0.6 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 Cucumovirus protein 2B RXT2_N PF08595.11 KXX72901.1 - 0.16 12.0 3.9 0.43 10.6 3.9 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Utp14 PF04615.13 KXX72901.1 - 0.7 8.4 3.7 1 7.8 3.7 1.3 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.12 KXX72901.1 - 0.84 7.8 6.2 1.2 7.3 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KXX72901.1 - 1 9.0 14.2 0.07 12.9 8.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KXX72901.1 - 1.9 7.7 8.0 2.7 7.2 8.0 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 KXX72901.1 - 2.9 7.7 7.5 5.2 6.9 7.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SnoaL_2 PF12680.7 KXX72903.1 - 0.00022 21.8 0.2 0.00031 21.3 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain YqgC PF17430.2 KXX72903.1 - 0.77 9.9 6.2 4.7 7.4 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized YqgC-like HTH_30 PF13556.6 KXX72905.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Beta-lactamase PF00144.24 KXX72906.1 - 7.3e-27 94.5 0.0 1.1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_43 PF04616.14 KXX72907.1 - 8.2e-16 58.2 1.3 1.3e-15 57.5 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KXX72907.1 - 0.014 15.0 0.3 0.17 11.4 0.0 2.1 1 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain DUF1996 PF09362.10 KXX72908.1 - 2.1e-81 273.4 1.1 2.6e-81 273.1 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Swi3 PF07962.12 KXX72909.1 - 1.2e-30 105.3 0.2 2.2e-30 104.4 0.2 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 MdcG PF10620.9 KXX72909.1 - 0.048 13.4 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG GFRP PF06399.13 KXX72909.1 - 0.25 11.3 1.1 11 6.0 0.1 2.9 1 1 2 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Snf7 PF03357.21 KXX72910.1 - 0.0033 17.0 25.0 0.0033 17.0 25.0 1.5 1 1 0 1 1 1 1 Snf7 DltD PF04914.12 KXX72910.1 - 0.59 9.5 14.0 0.85 8.9 14.0 1.1 1 0 0 1 1 1 0 DltD protein Bud13 PF09736.9 KXX72910.1 - 7.1 7.0 20.9 5.7 7.3 1.6 2.1 1 1 1 2 2 2 0 Pre-mRNA-splicing factor of RES complex DSHCT PF08148.12 KXX72911.1 - 5.2e-52 175.8 0.4 1.3e-51 174.6 0.4 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KXX72911.1 - 4.4e-39 133.4 0.0 5e-38 130.0 0.0 2.4 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KXX72911.1 - 1.6e-24 87.3 0.0 2.7e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KXX72911.1 - 7.2e-19 68.2 0.0 2.4e-18 66.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX72911.1 - 1.4e-06 28.6 0.0 7.8e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX72911.1 - 1.6e-05 25.0 0.0 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cut8 PF08559.10 KXX72911.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein NADH-u_ox-rdase PF10785.9 KXX72912.1 - 2.5e-30 105.0 0.8 4.2e-30 104.3 0.4 1.5 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KXX72912.1 - 1.5e-25 89.0 0.0 2.3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NTP_transf_9 PF04248.12 KXX72913.1 - 7.2e-22 77.1 0.0 9.3e-22 76.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.16 KXX72914.1 - 4.6e-47 160.7 37.6 4.6e-47 160.7 37.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX72914.1 - 1.6e-11 43.8 7.1 1.6e-11 43.8 7.1 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXX72914.1 - 1 7.6 5.3 0.6 8.3 2.7 2.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EI24 PF07264.11 KXX72915.1 - 0.013 15.7 3.7 0.031 14.5 3.7 1.6 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) FA_desaturase PF00487.24 KXX72915.1 - 0.41 10.5 2.4 8.9 6.1 0.3 2.4 2 0 0 2 2 2 0 Fatty acid desaturase F-box PF00646.33 KXX72916.1 - 0.00022 21.0 0.8 0.00063 19.6 0.8 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX72916.1 - 0.011 15.6 0.2 0.025 14.4 0.2 1.6 1 0 0 1 1 1 0 F-box-like Trypsin_2 PF13365.6 KXX72916.1 - 0.014 16.3 0.4 0.28 12.1 0.1 2.7 3 0 0 3 3 3 0 Trypsin-like peptidase domain Mito_carr PF00153.27 KXX72918.1 - 4.9e-71 234.7 4.5 1.8e-23 82.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXX72918.1 - 1.1e-05 24.7 0.8 0.0021 17.2 0.0 3.3 3 1 1 4 4 4 2 Gammaproteobacterial serine protease PrcB_C PF14343.6 KXX72918.1 - 0.13 12.4 0.2 2.7 8.2 0.0 2.6 3 0 0 3 3 3 0 PrcB C-terminal MBOAT PF03062.19 KXX72919.1 - 6.8e-33 114.5 15.1 6.8e-33 114.5 15.1 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXX72919.1 - 8.3e-06 26.0 4.6 2.1e-05 24.7 4.6 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ribosomal_L18 PF17135.4 KXX72920.1 - 1.7e-93 311.2 4.3 1.9e-93 311.1 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KXX72920.1 - 0.0017 19.0 0.1 0.0017 19.0 0.1 1.9 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TBPIP PF07106.13 KXX72920.1 - 0.058 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain RRM_1 PF00076.22 KXX72921.1 - 9.1e-12 44.6 0.0 1.2e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXX72921.1 - 8.2e-05 22.5 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FtsJ PF01728.19 KXX72922.1 - 8.7e-51 172.5 0.3 1.6e-50 171.7 0.3 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KXX72922.1 - 0.022 14.6 0.0 0.096 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXX72922.1 - 0.13 13.0 0.0 0.55 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXX72922.1 - 0.17 11.7 0.0 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain EF-hand_like PF09279.11 KXX72923.1 - 2.2e-11 44.1 15.1 0.013 16.0 0.8 4.5 1 1 5 6 6 6 6 Phosphoinositide-specific phospholipase C, efhand-like APA3_viroporin PF11289.8 KXX72923.1 - 0.0029 17.2 5.6 2.5 7.6 0.5 3.8 2 1 4 6 6 6 3 Coronavirus accessory protein 3a DUF4093 PF13331.6 KXX72923.1 - 0.013 15.9 2.6 0.23 11.9 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4093) DUF3519 PF12033.8 KXX72923.1 - 0.022 15.1 8.8 29 5.1 0.3 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3519) Pectinesterase PF01095.19 KXX72923.1 - 0.11 11.2 1.4 23 3.5 0.0 3.0 1 1 1 3 3 3 0 Pectinesterase FAM219A PF15260.6 KXX72923.1 - 0.29 11.5 11.1 6.6 7.1 1.1 3.8 1 1 3 4 4 4 0 Protein family FAM219A DUF3328 PF11807.8 KXX72924.1 - 0.003 17.4 3.4 0.0058 16.4 3.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Neurensin PF14927.6 KXX72924.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.4 1 1 0 1 1 1 0 Neurensin GFA PF04828.14 KXX72925.1 - 0.001 19.3 0.6 0.001 19.3 0.6 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.6 KXX72925.1 - 0.059 12.8 0.2 0.059 12.8 0.2 2.5 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KXX72925.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.5 3 0 0 3 3 3 0 A2L zinc ribbon domain DUF2318 PF10080.9 KXX72925.1 - 0.74 10.0 5.1 0.25 11.5 0.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) DUF2347 PF09804.9 KXX72928.1 - 1e-101 340.2 0.0 1.3e-101 339.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KXX72928.1 - 2e-65 220.8 0.0 3.5e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 KXX72928.1 - 0.00048 20.1 0.0 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KXX72928.1 - 0.016 13.9 0.0 0.094 11.4 0.0 1.9 2 0 0 2 2 2 0 Transport protein Avl9 WD40 PF00400.32 KXX72929.1 - 7.5e-52 172.2 7.4 1.6e-08 35.1 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Tup_N PF08581.10 KXX72929.1 - 5.3e-18 65.1 11.0 9.4e-18 64.3 11.0 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KXX72929.1 - 7.8e-13 48.5 0.0 0.00014 22.1 0.0 4.7 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXX72929.1 - 2.1e-05 24.0 0.0 0.13 11.6 0.0 3.7 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KXX72929.1 - 2.8e-05 23.3 0.1 0.19 10.7 0.0 3.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXX72929.1 - 8.6e-05 21.4 0.1 0.22 10.1 0.0 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KXX72929.1 - 0.0057 15.2 0.0 1.4 7.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain Golgin_A5 PF09787.9 KXX72929.1 - 0.069 12.6 5.8 0.11 12.0 5.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nbas_N PF15492.6 KXX72929.1 - 0.08 12.3 0.1 18 4.6 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Mcl1_mid PF12341.8 KXX72929.1 - 0.085 12.2 0.0 0.31 10.3 0.0 1.7 1 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region NACHT PF05729.12 KXX72930.1 - 3e-09 37.0 0.0 8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX72930.1 - 5.7e-07 30.1 0.1 3.5e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX72930.1 - 1.5e-05 25.3 0.1 0.00085 19.6 0.0 3.3 4 0 0 4 4 4 1 AAA domain SesA PF17107.5 KXX72930.1 - 0.007 16.6 0.1 0.045 13.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_29 PF13555.6 KXX72930.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ISG65-75 PF11727.8 KXX72930.1 - 0.03 13.5 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein ABC_tran PF00005.27 KXX72930.1 - 0.035 14.6 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KXX72930.1 - 0.058 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KXX72930.1 - 0.08 13.0 2.4 3 7.9 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 KXX72930.1 - 0.088 13.4 1.1 0.56 10.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXX72930.1 - 0.18 12.2 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 KXX72930.1 - 0.26 11.7 3.4 0.28 11.7 0.0 2.6 3 1 1 4 4 4 0 AAA domain CRR7 PF12095.8 KXX72930.1 - 0.57 10.7 4.8 2.5 8.6 0.2 3.4 4 0 0 4 4 2 0 Protein CHLORORESPIRATORY REDUCTION 7 NifW PF03206.14 KXX72930.1 - 2.8 8.5 6.6 2.2 8.9 0.5 3.5 4 0 0 4 4 4 0 Nitrogen fixation protein NifW Cation_ATPase_C PF00689.21 KXX72931.1 - 1.4e-44 152.0 6.7 1.7e-44 151.8 3.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXX72931.1 - 3.5e-34 117.9 0.1 3.5e-34 117.9 0.1 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXX72931.1 - 5.1e-22 77.8 0.0 1.3e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX72931.1 - 1e-10 42.2 0.1 2.6e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXX72931.1 - 0.012 15.3 0.2 4.6 6.9 0.1 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX72931.1 - 0.037 13.7 0.2 0.31 10.7 0.0 2.7 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus DUF4149 PF13664.6 KXX72931.1 - 0.12 12.6 1.6 0.57 10.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Phage_holin_1 PF04531.13 KXX72931.1 - 1.8 9.1 4.0 8.8 6.9 0.1 3.0 2 0 0 2 2 2 0 Bacteriophage holin BUD22 PF09073.10 KXX72932.1 - 4.3 6.6 28.9 4.9 6.4 28.9 1.0 1 0 0 1 1 1 0 BUD22 DUF3659 PF12396.8 KXX72934.1 - 6.9e-101 330.2 53.8 2.2e-22 78.7 2.2 5.2 5 0 0 5 5 5 5 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 KXX72934.1 - 0.002 18.0 0.8 16 5.5 0.0 4.5 4 0 0 4 4 4 2 Glycine cleavage T-protein C-terminal barrel domain Trypan_PARP PF05887.11 KXX72934.1 - 0.0051 16.8 0.3 0.0051 16.8 0.3 5.2 3 1 3 6 6 6 1 Procyclic acidic repetitive protein (PARP) AF-4 PF05110.13 KXX72934.1 - 4.5 5.2 35.0 6.3 4.8 35.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3659 PF12396.8 KXX72935.1 - 3.6e-16 58.8 2.3 4.2e-11 42.6 0.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) ORC6 PF05460.13 KXX72935.1 - 0.57 9.4 6.8 0.77 9.0 6.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4551 PF15087.6 KXX72935.1 - 3.9 6.2 4.8 4.6 6.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Fungal_trans_2 PF11951.8 KXX72937.1 - 0.027 13.3 0.2 0.073 11.9 0.0 1.7 1 1 1 2 2 2 0 Fungal specific transcription factor domain DUF5353 PF17304.2 KXX72938.1 - 6.3e-07 29.0 5.0 6.3e-07 29.0 5.0 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF5353) Osteoregulin PF07175.11 KXX72938.1 - 0.043 14.0 1.4 0.072 13.3 0.3 1.7 1 1 1 2 2 2 0 Osteoregulin CHCH PF06747.13 KXX72939.1 - 8e-07 29.0 6.0 1.3e-06 28.4 6.0 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KXX72939.1 - 0.18 12.2 1.9 0.35 11.3 1.9 1.5 1 0 0 1 1 1 0 GCK domain PepSY_TM PF03929.16 KXX72939.1 - 3.1 7.4 6.2 0.47 10.1 0.1 2.0 2 0 0 2 2 2 0 PepSY-associated TM region COX14 PF14880.6 KXX72940.1 - 5.5e-18 64.6 1.9 5.5e-18 64.6 1.9 2.4 2 0 0 2 2 2 1 Cytochrome oxidase c assembly MatB PF16449.5 KXX72942.1 - 0.14 11.9 0.1 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Fimbrillin MatB PAP1 PF08601.10 KXX72942.1 - 2.8 7.6 6.2 4.7 6.8 6.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Ribosomal_L50 PF10501.9 KXX72943.1 - 5.7e-19 68.3 0.0 1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Ribosomal_L13e PF01294.18 KXX72944.1 - 9.1e-76 253.7 1.4 1.2e-75 253.3 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e TPR_10 PF13374.6 KXX72946.1 - 1.7e-39 132.6 2.4 1.7e-11 43.6 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXX72946.1 - 3.9e-34 116.8 3.2 3.4e-14 52.9 0.1 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX72946.1 - 4.4e-11 42.0 0.2 0.0052 16.7 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX72946.1 - 4.4e-09 36.2 3.0 6.5e-09 35.6 3.0 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_4 PF07721.14 KXX72946.1 - 5.7e-09 35.7 0.3 0.27 12.0 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX72946.1 - 6.5e-08 33.1 0.2 1.7 9.4 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX72946.1 - 5.4e-07 29.2 0.7 0.52 10.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KXX72946.1 - 1.4e-05 24.4 0.0 3.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 KXX72946.1 - 4.5e-05 23.1 0.1 0.5 10.3 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX72946.1 - 8e-05 23.1 3.3 20 6.3 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXX72946.1 - 9.8e-05 22.5 0.0 0.42 11.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX72946.1 - 0.00036 21.0 0.1 5.8 7.5 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.12 KXX72946.1 - 0.0029 17.5 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ses_B PF17046.5 KXX72946.1 - 0.0074 16.2 0.4 0.013 15.4 0.4 1.4 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein TPR_8 PF13181.6 KXX72946.1 - 0.011 15.9 0.8 8.5 6.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 KXX72946.1 - 0.039 14.2 0.1 61 3.9 0.0 3.2 1 1 2 3 3 3 0 Tetratrico peptide repeat NDUF_B8 PF05821.11 KXX72947.1 - 5.2e-06 26.4 3.0 8.7e-06 25.7 3.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) MFS_1 PF07690.16 KXX72948.1 - 3.5e-40 138.0 64.3 1e-33 116.7 18.9 3.9 2 1 1 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 KXX72948.1 - 1e-09 37.4 26.6 1.5e-09 36.9 26.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) APH PF01636.23 KXX72951.1 - 1.1e-14 54.9 0.0 7e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXX72951.1 - 1.2e-08 34.9 0.1 2.2e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KXX72951.1 - 0.00092 18.5 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase p450 PF00067.22 KXX72952.1 - 2.5e-63 214.5 0.0 3.1e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.19 KXX72953.1 - 6.5e-41 140.2 3.9 8.3e-41 139.9 3.9 1.1 1 0 0 1 1 1 1 Pectate lyase RabGAP-TBC PF00566.18 KXX72954.1 - 2.4e-33 115.6 0.0 4e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_tranf_2_3 PF13641.6 KXX72955.1 - 6.2e-29 101.5 0.1 8.6e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXX72955.1 - 1.5e-08 34.3 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXX72955.1 - 1.4e-06 28.2 0.2 8.1e-06 25.7 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_64 PF09258.10 KXX72955.1 - 0.0084 15.4 0.3 0.014 14.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain HAD_SAK_2 PF18143.1 KXX72955.1 - 0.092 13.1 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins BCS1_N PF08740.11 KXX72956.1 - 1.3e-49 168.7 1.4 2e-49 168.2 1.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXX72956.1 - 2.2e-16 60.5 0.0 1.6e-07 31.8 0.0 2.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX72956.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXX72956.1 - 0.041 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXX72956.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX72956.1 - 0.073 13.4 0.4 0.36 11.2 0.1 2.1 1 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KXX72956.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC Tau95_N PF17682.1 KXX72957.1 - 2.2e-39 134.6 0.3 5.2e-39 133.3 0.0 1.8 2 0 0 2 2 2 1 Tau95 Triple barrel domain Tau95 PF09734.9 KXX72957.1 - 1.1e-36 126.7 0.1 2.3e-36 125.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain NAP PF00956.18 KXX72958.1 - 1.5e-22 80.0 1.9 9e-20 71.0 0.1 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Asparaginase PF00710.20 KXX72959.1 - 2.9e-57 193.3 0.0 4.2e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXX72959.1 - 5.8e-26 91.0 0.0 9.5e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank PF00023.30 KXX72959.1 - 7.4e-07 29.3 0.4 9.2e-05 22.7 0.2 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXX72959.1 - 0.00016 21.9 0.2 0.00052 20.3 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX72959.1 - 0.00029 21.4 0.1 0.0012 19.3 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX72959.1 - 0.0005 20.6 0.2 0.002 18.6 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX72959.1 - 0.029 14.9 0.3 0.56 10.9 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat DUF2461 PF09365.10 KXX72960.1 - 3.8e-79 265.5 0.0 1e-78 264.1 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) PBP1_TM PF14812.6 KXX72960.1 - 7.4 7.0 8.9 2.8 8.4 5.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NACHT_sigma PF17106.5 KXX72961.1 - 2.1e-15 56.6 15.1 3.1e-15 56.0 15.1 1.3 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases ABC_tran_CTD PF16326.5 KXX72962.1 - 0.023 14.9 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Ank_2 PF12796.7 KXX72964.1 - 2.2e-45 153.1 6.1 6.3e-11 42.7 0.6 6.6 4 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX72964.1 - 2.6e-43 141.0 5.5 0.0015 18.8 0.1 11.9 11 1 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 KXX72964.1 - 1.7e-41 139.7 11.9 6.1e-09 36.0 0.3 9.6 5 2 5 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX72964.1 - 1.5e-36 124.3 7.6 8.5e-09 35.8 0.1 8.7 6 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KXX72964.1 - 1.6e-36 123.1 14.6 2e-07 31.1 0.1 11.2 11 1 0 11 11 11 8 Ankyrin repeat DUF2384 PF09722.10 KXX72964.1 - 0.14 12.2 0.1 2 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) CDO_I PF05995.12 KXX72965.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXX72965.1 - 0.0017 17.8 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 PCO_ADO MFS_1 PF07690.16 KXX72966.1 - 3.8e-24 85.3 35.5 8.2e-24 84.2 35.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX72966.1 - 2.4e-16 59.3 10.0 3e-16 59.0 10.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX72966.1 - 6e-09 35.3 8.4 1.1e-08 34.5 8.4 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KXX72966.1 - 0.16 10.3 3.9 0.16 10.3 0.9 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ank_3 PF13606.6 KXX72967.1 - 0.0015 18.8 1.0 90 4.2 0.0 6.4 7 1 1 8 8 8 0 Ankyrin repeat Ank_4 PF13637.6 KXX72967.1 - 0.0042 17.6 0.1 1.5e+02 3.1 0.0 5.3 5 1 1 6 6 6 0 Ankyrin repeats (many copies) p450 PF00067.22 KXX72968.1 - 3.5e-74 250.2 0.0 4.3e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SET PF00856.28 KXX72970.1 - 1.2e-13 51.8 0.0 4.5e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 SET domain DIX PF00778.17 KXX72970.1 - 0.19 11.6 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 DIX domain DUF829 PF05705.14 KXX72971.1 - 3.7e-68 230.0 0.0 4.2e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Hexokinase_2 PF03727.16 KXX72973.1 - 1.9e-55 187.9 0.0 2.5e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXX72973.1 - 4e-44 150.9 0.0 6e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.20 KXX72974.1 - 1.3e-23 84.1 0.0 2e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NDT80_PhoG PF05224.12 KXX72975.1 - 3.3e-34 118.7 0.0 7.5e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family RGCC PF15151.6 KXX72976.1 - 0.044 14.0 0.3 0.075 13.3 0.3 1.6 1 1 0 1 1 1 0 Response gene to complement 32 protein family Plasmod_MYXSPDY PF07981.11 KXX72976.1 - 0.045 13.7 25.6 0.15 12.1 2.5 5.3 1 1 4 5 5 5 0 Plasmodium repeat_MYXSPDY Cullin PF00888.22 KXX72977.1 - 2.7e-24 85.7 0.0 4.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KXX72977.1 - 1.5e-21 76.7 0.2 3.5e-21 75.5 0.2 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.10 KXX72977.1 - 0.15 12.2 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator Baculo_PEP_C PF04513.12 KXX72978.1 - 0.032 14.3 0.5 11 6.0 0.2 4.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KXX72978.1 - 0.058 13.3 0.3 9.9 6.0 0.0 4.0 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain DUF148 PF02520.17 KXX72978.1 - 0.18 12.0 0.0 4.3 7.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF148 LEP503 PF15221.6 KXX72978.1 - 0.18 12.1 0.1 0.48 10.8 0.1 1.7 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 DUF1664 PF07889.12 KXX72978.1 - 0.6 10.2 8.0 3.3 7.8 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KXX72978.1 - 0.93 9.8 2.3 35 4.8 0.0 4.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 7TM_GPCR_Str PF10326.9 KXX72980.1 - 0.031 13.6 2.6 0.044 13.1 2.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str MgtE PF01769.16 KXX72980.1 - 0.059 13.7 1.5 0.096 13.1 1.5 1.4 1 0 0 1 1 1 0 Divalent cation transporter 7tm_7 PF08395.12 KXX72980.1 - 0.082 12.1 3.4 0.12 11.6 3.4 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor TPR_10 PF13374.6 KXX72981.1 - 3.8e-16 58.4 0.1 1.1e-07 31.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX72981.1 - 7.1e-14 51.9 1.2 2.1e-13 50.3 0.0 2.3 3 0 0 3 3 2 1 Tetratricopeptide repeat NB-ARC PF00931.22 KXX72981.1 - 3.2e-08 33.1 0.0 6.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 KXX72981.1 - 3.3e-07 29.9 0.1 0.014 15.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX72981.1 - 8.8e-06 25.5 0.1 0.018 15.1 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF676 PF05057.14 KXX72981.1 - 8.3e-05 22.2 0.0 0.015 14.8 0.0 2.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) TPR_16 PF13432.6 KXX72981.1 - 0.00022 21.8 0.0 0.0015 19.2 0.0 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXX72981.1 - 0.00097 19.5 0.0 1.7 9.5 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat PGAP1 PF07819.13 KXX72981.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein TPR_1 PF00515.28 KXX72981.1 - 0.0012 18.6 0.0 1.2 9.1 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXX72981.1 - 0.0016 18.7 0.0 0.0057 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.6 KXX72981.1 - 0.0061 17.0 0.1 0.06 13.9 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX72981.1 - 0.013 16.2 1.3 43 5.3 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX72981.1 - 0.059 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region Zeta_toxin PF06414.12 KXX72981.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KXX72981.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 KXX72981.1 - 0.12 12.7 0.0 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 KXX72981.1 - 0.22 11.3 0.0 1.1 9.0 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Git3 PF11710.8 KXX72982.1 - 1.7e-58 197.7 16.5 2.8e-58 197.0 16.5 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXX72982.1 - 9.5e-28 96.1 0.0 9.5e-28 96.1 0.0 3.6 4 0 0 4 4 4 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF4512 PF14975.6 KXX72982.1 - 0.41 11.4 7.9 25 5.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Mucin PF01456.17 KXX72982.1 - 0.48 10.4 51.6 0.069 13.1 43.4 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF572 PF04502.13 KXX72982.1 - 2 8.0 5.5 2.9 7.4 5.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GET2 PF08690.10 KXX72982.1 - 2.1 8.0 7.9 0.7 9.5 4.4 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 DUF4834 PF16118.5 KXX72982.1 - 4.4 8.3 6.4 35 5.5 2.8 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) CLP1_P PF16575.5 KXX72983.1 - 6.4e-32 110.9 0.0 1.5e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KXX72983.1 - 1.2e-25 89.5 0.0 1.9e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KXX72983.1 - 2.5e-24 86.0 0.0 4.7e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CbiA PF01656.23 KXX72983.1 - 0.0027 17.8 0.0 0.0057 16.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KXX72983.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXX72983.1 - 0.038 14.1 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KXX72983.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXX72983.1 - 0.088 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 KXX72983.1 - 0.11 12.0 0.1 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_18 PF13238.6 KXX72983.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXX72983.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX72983.1 - 0.17 12.3 0.1 0.43 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain IPK PF03770.16 KXX72984.1 - 1.5e-50 171.8 0.0 2.1e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.10 KXX72985.1 - 7.1e-17 61.7 0.2 7.2e-17 61.7 0.2 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Arb1 PF09692.10 KXX72986.1 - 5.6e-31 108.1 1.0 5.1e-18 65.4 0.1 2.5 2 1 0 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DNA_binding_1 PF01035.20 KXX72987.1 - 1.1e-28 99.2 0.0 1.5e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Endonuc-HincII PF09226.11 KXX72987.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease HincII ubiquitin PF00240.23 KXX72989.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KXX72989.1 - 0.018 15.7 0.0 0.03 15.0 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Exo_endo_phos PF03372.23 KXX72990.1 - 4.4e-08 32.9 0.2 8.9e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Nop PF01798.18 KXX72991.1 - 8.8e-79 264.2 0.1 8.8e-79 264.2 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin adh_short PF00106.25 KXX72993.1 - 2e-34 118.7 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX72993.1 - 2e-25 89.7 0.0 3.1e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX72993.1 - 1.8e-07 31.3 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX72993.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 KXX72993.1 - 0.053 13.4 0.2 0.087 12.7 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Hormone_recep PF00104.30 KXX72993.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor NmrA PF05368.13 KXX72994.1 - 3.2e-35 121.8 0.0 3.7e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX72994.1 - 4.3e-11 43.0 0.1 5.9e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX72994.1 - 0.00016 21.2 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX72994.1 - 0.044 12.8 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KXX72994.1 - 0.16 12.4 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Lipase_GDSL_2 PF13472.6 KXX72996.1 - 8.5e-19 68.6 0.2 1.3e-18 68.1 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX72996.1 - 2.4e-10 40.7 0.0 4.4e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PFL-like PF02901.15 KXX72996.1 - 0.083 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like Glyco_hydro_61 PF03443.14 KXX72997.1 - 4.8e-62 209.5 0.0 1.2e-61 208.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 KXX72998.1 - 8.6e-18 64.3 0.0 1.6e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX72998.1 - 5e-09 36.1 8.5 8.7e-09 35.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KXX72998.1 - 0.00089 19.3 2.9 0.003 17.6 2.9 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 KXX72998.1 - 3.7 7.5 11.1 6 6.7 11.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4551 PF15087.6 KXX72998.1 - 4.3 6.0 7.8 6.6 5.4 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Roughex PF06020.11 KXX72998.1 - 7.1 5.6 7.2 11 5.0 7.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 KXX72998.1 - 7.2 6.1 17.2 13 5.3 17.2 1.4 1 0 0 1 1 1 0 Spt20 family Senescence PF06911.12 KXX72999.1 - 1.1e-59 201.9 4.6 2.2e-59 200.8 4.6 1.6 1 0 0 1 1 1 1 Senescence-associated protein PQQ_3 PF13570.6 KXX72999.1 - 0.023 15.2 0.2 0.13 12.8 0.2 2.4 1 0 0 1 1 1 0 PQQ-like domain GCP_N_terminal PF17681.1 KXX73000.1 - 4.5e-23 82.3 0.0 1.4e-22 80.7 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXX73000.1 - 1.6e-18 67.2 0.0 1.8e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Glyco_hydro_18 PF00704.28 KXX73001.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 p450 PF00067.22 KXX73002.1 - 5.8e-22 78.1 0.0 7.1e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SQHop_cyclase_C PF13243.6 KXX73003.1 - 0.036 13.2 0.0 0.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain CVNH PF08881.10 KXX73004.1 - 3.2e-20 72.7 0.7 6.9e-11 42.7 0.2 2.1 2 0 0 2 2 2 2 CVNH domain Metallophos PF00149.28 KXX73006.1 - 5.3e-15 56.5 0.0 9.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX73006.1 - 2.1e-06 28.0 0.2 5e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.31 KXX73007.1 - 1.5e-18 66.6 2.1 3.3e-18 65.5 2.1 1.6 1 0 0 1 1 1 1 DnaJ domain RNA_pol PF00940.19 KXX73009.1 - 4e-188 625.4 0.0 5.8e-188 624.9 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KXX73009.1 - 1.2e-99 334.0 0.1 2.2e-99 333.0 0.1 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DHHA2 PF02833.14 KXX73010.1 - 2.5e-36 125.0 0.0 3.6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KXX73010.1 - 8.3e-11 42.0 0.0 3.4e-10 40.1 0.0 1.8 1 1 1 2 2 2 1 DHH family RsfS PF02410.15 KXX73011.1 - 2.8e-14 53.4 0.0 5.5e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation SH3_3 PF08239.11 KXX73012.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Glyco_hydro_47 PF01532.20 KXX73013.1 - 1.4e-111 373.6 0.0 1.8e-111 373.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_3 PF00933.21 KXX73014.1 - 3.6e-52 177.7 0.0 5.2e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXX73014.1 - 1.7e-46 158.8 0.4 3.8e-46 157.6 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXX73014.1 - 9.9e-24 83.2 1.1 9.9e-24 83.2 1.1 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 KXX73014.1 - 0.024 14.9 0.3 0.099 13.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF11 CARDB PF07705.11 KXX73014.1 - 0.12 12.6 0.2 0.35 11.2 0.2 1.8 1 0 0 1 1 1 0 CARDB Sugar-bind PF04198.13 KXX73014.1 - 0.16 11.1 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain Con-6 PF10346.9 KXX73015.1 - 5.8e-29 99.8 2.2 5.4e-14 51.9 0.2 2.5 2 0 0 2 2 2 2 Conidiation protein 6 P16-Arc PF04699.14 KXX73015.1 - 0.0087 16.6 0.3 0.46 11.0 0.1 2.2 2 0 0 2 2 2 2 ARP2/3 complex 16 kDa subunit (p16-Arc) TetR_C_28 PF17937.1 KXX73015.1 - 0.11 13.0 0.0 2.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HET PF06985.11 KXX73016.1 - 2.4e-14 53.9 4.9 3.2e-11 43.8 0.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.7 KXX73017.1 - 1.9e-22 79.5 1.6 3.7e-22 78.5 1.6 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) GMC_oxred_N PF00732.19 KXX73018.1 - 4.1e-58 197.1 0.0 5.9e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX73018.1 - 9e-29 100.9 0.2 1.6e-28 100.1 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXX73018.1 - 5e-06 25.8 0.2 1.1e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KXX73018.1 - 0.0012 18.2 0.1 0.0026 17.1 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXX73018.1 - 0.0021 18.2 0.0 0.0071 16.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX73018.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX73018.1 - 0.026 14.1 0.0 0.095 12.3 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX73018.1 - 0.084 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KXX73019.1 - 0.00054 19.8 0.8 0.001 18.9 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXX73019.1 - 0.0013 18.6 0.1 0.0032 17.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain Aldo_ket_red PF00248.21 KXX73020.1 - 1.5e-51 175.4 0.0 1.7e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 KXX73021.1 - 1.4e-05 24.6 0.0 3.2e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Sec2p PF06428.11 KXX73023.1 - 2.5e-29 101.1 16.9 2.5e-29 101.1 16.9 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.8 KXX73023.1 - 5.6e-05 20.9 19.1 7.6e-05 20.5 19.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF5401 PF17380.2 KXX73023.1 - 0.0039 15.4 15.8 0.006 14.7 15.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5401) Med9 PF07544.13 KXX73023.1 - 0.56 10.3 16.8 0.35 11.0 4.7 3.2 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 KASH_CCD PF14662.6 KXX73023.1 - 0.76 9.6 25.6 1.6 8.5 25.5 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Lar_restr_allev PF14354.6 KXX73023.1 - 1.8 9.0 3.1 0.82 10.1 0.2 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar HLH PF00010.26 KXX73024.1 - 3.5e-18 65.3 0.1 6.4e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 KXX73024.1 - 0.11 12.6 0.4 0.23 11.6 0.4 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation DMPK_coil PF08826.10 KXX73024.1 - 0.16 12.1 0.5 0.33 11.1 0.2 1.6 2 0 0 2 2 2 0 DMPK coiled coil domain like FAM220 PF15487.6 KXX73024.1 - 0.26 10.9 5.0 0.37 10.4 5.0 1.2 1 0 0 1 1 1 0 FAM220 family Hamartin PF04388.12 KXX73024.1 - 0.89 8.1 6.8 0.99 8.0 6.8 1.1 1 0 0 1 1 1 0 Hamartin protein Yip1 PF04893.17 KXX73025.1 - 0.019 14.7 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain Bacteriocin_IIc PF10439.9 KXX73025.1 - 0.72 10.0 8.6 1.1 9.5 8.6 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide CDH-cyt PF16010.5 KXX73026.1 - 4.2e-57 192.8 0.2 4.9e-57 192.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase UCR_TM PF02921.14 KXX73027.1 - 4.2e-09 36.8 1.2 4.2e-09 36.8 1.2 2.2 2 1 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region MMS1_N PF10433.9 KXX73028.1 - 1.2e-123 413.4 0.0 1.7e-123 412.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXX73028.1 - 2.5e-68 230.8 0.1 8e-67 225.8 0.0 3.1 3 1 1 4 4 4 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KXX73028.1 - 0.017 15.4 0.1 53 4.2 0.0 5.4 4 1 1 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 KXX73029.1 - 6.1e-36 124.2 0.1 3.5e-24 85.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Asp_protease_2 PF13650.6 KXX73030.1 - 0.032 14.9 0.0 0.048 14.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 KXX73032.1 - 0.019 15.0 0.3 0.049 13.8 0.3 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 KXX73032.1 - 0.036 14.1 0.1 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXX73032.1 - 0.079 13.3 0.2 0.31 11.3 0.1 2.0 1 1 0 2 2 2 0 RNase H-like domain found in reverse transcriptase EPSP_synthase PF00275.20 KXX73034.1 - 2.5e-130 434.9 0.1 4.6e-130 434.1 0.1 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KXX73034.1 - 3.5e-101 337.8 0.0 6e-101 337.0 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KXX73034.1 - 2e-57 195.1 0.0 3.6e-57 194.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KXX73034.1 - 1.6e-37 129.1 0.0 8.8e-36 123.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KXX73034.1 - 6.9e-25 87.1 0.0 1.8e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KXX73034.1 - 2.3e-07 30.8 0.0 4.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KXX73034.1 - 6e-06 25.9 0.6 1.8e-05 24.4 0.6 1.9 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXX73034.1 - 2.9e-05 24.2 0.1 9.8e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_18 PF13238.6 KXX73034.1 - 0.026 15.1 0.0 0.069 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX73034.1 - 0.076 13.4 0.3 0.6 10.5 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AA_permease PF00324.21 KXX73035.1 - 3e-136 454.8 39.0 3.7e-136 454.5 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX73035.1 - 2.7e-38 131.9 44.5 3.5e-38 131.5 44.5 1.1 1 0 0 1 1 1 1 Amino acid permease RVT_1 PF00078.27 KXX73036.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HisKA PF00512.25 KXX73036.1 - 3.9 7.6 5.7 9.1 6.4 0.5 3.3 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain TPR_2 PF07719.17 KXX73037.1 - 6.5e-21 72.7 13.3 1.9e-05 24.4 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXX73037.1 - 1.1e-19 69.3 10.7 2.5e-06 27.1 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXX73037.1 - 2.6e-15 56.8 13.3 1.7e-05 25.3 0.1 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXX73037.1 - 4.7e-15 55.0 9.6 1.1e-07 31.3 0.1 5.0 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 KXX73037.1 - 4.3e-14 52.0 11.7 0.00032 21.2 0.0 6.2 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX73037.1 - 5.9e-14 51.0 0.9 0.004 17.2 0.0 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXX73037.1 - 1.5e-12 47.0 7.5 0.0037 17.5 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXX73037.1 - 1.6e-12 47.7 9.3 0.00025 21.5 4.6 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXX73037.1 - 2e-11 43.8 1.3 0.0025 17.9 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX73037.1 - 2.3e-11 42.9 4.2 0.1 12.7 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX73037.1 - 8.5e-10 38.8 11.7 0.0072 16.6 3.2 4.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.6 KXX73037.1 - 5.1e-09 36.3 4.5 0.0054 17.0 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXX73037.1 - 6.7e-08 32.7 2.2 0.74 10.6 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXX73037.1 - 5.2e-05 22.6 1.3 0.25 10.5 0.5 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX73037.1 - 0.00075 19.7 6.0 0.033 14.4 0.7 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 CRISPR_Cse2 PF09485.10 KXX73037.1 - 0.029 14.9 0.9 0.029 14.9 0.9 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_3 PF07720.12 KXX73037.1 - 0.062 13.3 0.1 15 5.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1641 PF07849.11 KXX73037.1 - 0.11 12.4 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) MIT PF04212.18 KXX73037.1 - 0.41 10.7 3.2 20 5.4 0.1 3.5 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 KXX73037.1 - 0.5 10.4 3.2 0.96 9.5 0.1 2.9 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 KXX73037.1 - 1 9.4 14.2 0.7 9.8 0.9 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 KXX73038.1 - 5.1e-34 115.9 0.0 2.2e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KXX73038.1 - 0.0078 16.0 0.0 1.3 8.8 0.0 3.1 2 1 1 3 3 3 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KXX73038.1 - 0.015 15.4 0.0 7.5 6.8 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif SET PF00856.28 KXX73039.1 - 1.6e-10 41.6 0.0 3.9e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 KXX73039.1 - 5.7e-09 35.9 6.7 5.7e-09 35.9 6.7 2.3 2 0 0 2 2 2 1 MYND finger DUF2484 PF10658.9 KXX73039.1 - 0.032 14.5 0.8 0.074 13.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) TarH PF02203.15 KXX73039.1 - 0.093 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue RNase_T PF00929.24 KXX73040.1 - 6.6e-07 30.0 0.0 1.8e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Exonuclease Prefoldin PF02996.17 KXX73041.1 - 6.2e-25 87.4 0.5 8e-25 87.1 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXX73041.1 - 0.0012 18.7 2.3 0.44 10.5 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.13 KXX73041.1 - 0.024 15.1 0.3 0.055 13.9 0.2 1.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.11 KXX73041.1 - 0.05 13.7 0.3 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CLZ PF16526.5 KXX73041.1 - 0.27 11.6 1.2 5.6 7.4 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CDH-cyt PF16010.5 KXX73042.1 - 8.9e-14 51.6 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KXX73042.1 - 0.00047 20.3 7.0 0.00049 20.2 3.2 2.7 1 1 2 3 3 3 1 Eukaryotic cytochrome b561 DUF4184 PF13803.6 KXX73042.1 - 0.012 15.4 0.1 0.027 14.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) Ferric_reduct PF01794.19 KXX73042.1 - 0.26 11.4 12.2 1 9.5 1.1 3.1 2 1 2 4 4 4 0 Ferric reductase like transmembrane component DUF4079 PF13301.6 KXX73042.1 - 1.3 9.2 7.3 2.1 8.5 3.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF2306 PF10067.9 KXX73042.1 - 1.4 9.1 14.1 2.5 8.3 6.8 2.7 2 1 0 3 3 3 0 Predicted membrane protein (DUF2306) Glyco_hydro_43 PF04616.14 KXX73043.1 - 4.8e-11 42.5 3.4 9.1e-11 41.6 3.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 IgG_binding_B PF01378.17 KXX73043.1 - 0.084 12.9 1.2 0.72 9.9 0.4 2.9 3 0 0 3 3 3 0 B domain MFS_1 PF07690.16 KXX73046.1 - 1.9e-23 83.0 53.6 1e-21 77.3 43.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXX73046.1 - 0.0075 15.6 30.0 0.016 14.5 30.0 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 KXX73047.1 - 1e-06 27.9 2.3 1.1e-06 27.9 2.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PLDc_N PF13396.6 KXX73047.1 - 0.065 13.2 8.4 0.21 11.5 8.4 1.8 1 1 0 1 1 1 0 Phospholipase_D-nuclease N-terminal OATP PF03137.20 KXX73047.1 - 0.24 9.6 1.7 0.26 9.5 1.7 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_2 PF07992.14 KXX73048.1 - 0.00059 19.2 0.1 0.00079 18.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX73048.1 - 0.0026 17.1 0.1 0.0036 16.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX73048.1 - 0.0039 16.0 0.1 0.0053 15.5 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXX73048.1 - 0.007 15.5 0.1 0.0099 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX73048.1 - 0.021 15.1 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX73048.1 - 0.023 13.8 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXX73048.1 - 0.044 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXX73048.1 - 0.11 11.6 0.2 0.16 11.0 0.2 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXX73048.1 - 0.2 10.8 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N PF00107.26 KXX73049.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Acetyltransf_3 PF13302.7 KXX73050.1 - 2.1e-22 80.3 0.0 3e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX73050.1 - 2.5e-06 27.4 0.2 0.0048 16.8 0.2 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KXX73050.1 - 3.3e-06 26.9 1.3 0.25 11.0 0.0 3.2 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX73050.1 - 0.00068 20.0 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX73050.1 - 0.0062 16.8 0.6 0.051 13.8 0.5 2.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXX73050.1 - 0.032 14.4 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXX73050.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PALP PF00291.25 KXX73051.1 - 5.4e-55 186.9 0.3 6.7e-55 186.6 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DNA_pol_E_B PF04042.16 KXX73052.1 - 6.1e-50 169.5 0.0 8.1e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KXX73052.1 - 6.9e-39 132.9 0.0 1.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain WD40 PF00400.32 KXX73053.1 - 7.8e-23 80.3 11.1 7.4e-07 29.8 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat NLE PF08154.12 KXX73053.1 - 3e-16 59.7 0.1 4.9e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KXX73053.1 - 0.00033 19.4 1.2 0.062 11.9 0.1 3.3 2 1 1 4 4 4 2 Nucleoporin Nup120/160 PQQ PF01011.21 KXX73053.1 - 0.08 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat tRNA-synt_1g PF09334.11 KXX73054.1 - 1.9e-92 310.0 0.9 5.1e-91 305.3 0.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXX73054.1 - 1.5e-22 79.7 7.2 2.7e-09 35.8 0.6 4.0 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KXX73054.1 - 1.6e-09 37.6 0.0 0.00073 19.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KXX73054.1 - 0.0093 15.9 0.0 0.073 13.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DNA_pol_A_exo1 PF01612.20 KXX73055.1 - 2.9e-12 46.7 0.0 4.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.6 KXX73055.1 - 0.037 14.5 0.0 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4786 PF16027.5 KXX73055.1 - 1 9.9 7.5 0.07 13.7 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4786) Peptidase_S49_N PF08496.10 KXX73055.1 - 9.3 6.3 7.8 24 5.0 7.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LSM PF01423.22 KXX73056.1 - 5.3e-23 80.5 0.2 5.9e-23 80.3 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXX73056.1 - 0.05 13.8 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KXX73056.1 - 0.13 12.3 0.0 0.18 12.0 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain MFS_1 PF07690.16 KXX73057.1 - 1.6e-37 129.3 26.1 1.6e-37 129.3 26.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Helo_like_N PF17111.5 KXX73059.1 - 5.1e-62 209.0 12.6 9.9e-61 204.7 5.7 2.6 2 1 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXX73059.1 - 0.0015 18.7 1.8 0.0022 18.2 0.1 2.1 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases SLATT_5 PF18160.1 KXX73059.1 - 0.01 15.2 0.4 0.02 14.2 0.4 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Med10 PF09748.9 KXX73059.1 - 0.011 15.7 1.0 0.21 11.6 0.1 2.5 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex KxDL PF10241.9 KXX73059.1 - 0.034 14.4 4.9 0.17 12.2 0.4 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein Rx_N PF18052.1 KXX73059.1 - 0.071 13.4 4.2 0.74 10.1 0.2 3.2 3 0 0 3 3 3 0 Rx N-terminal domain Tuberin PF03542.16 KXX73059.1 - 0.11 11.6 0.4 0.46 9.5 0.1 2.0 2 0 0 2 2 2 0 Tuberin IPK PF03770.16 KXX73059.1 - 0.11 12.3 1.7 0.34 10.7 0.2 2.2 2 1 0 2 2 2 0 Inositol polyphosphate kinase Occludin_ELL PF07303.13 KXX73059.1 - 0.12 13.1 0.4 16 6.3 0.2 2.8 2 1 0 2 2 2 0 Occludin homology domain SpecificRecomb PF10136.9 KXX73059.1 - 0.18 10.1 2.1 0.3 9.3 0.2 1.9 2 0 0 2 2 2 0 Site-specific recombinase V-SNARE PF05008.15 KXX73059.1 - 0.18 12.2 5.3 0.77 10.2 0.2 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus PriC PF07445.12 KXX73059.1 - 0.22 11.4 9.1 0.63 10.0 0.1 3.2 3 0 0 3 3 3 0 Primosomal replication protein priC NPV_P10 PF05531.12 KXX73059.1 - 0.25 11.8 2.0 0.59 10.6 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PilO PF04350.13 KXX73059.1 - 0.32 11.1 2.1 7 6.8 0.1 2.5 2 0 0 2 2 2 0 Pilus assembly protein, PilO SlyX PF04102.12 KXX73059.1 - 6.8 7.4 6.8 8.3 7.1 0.1 3.3 3 0 0 3 3 3 0 SlyX Toxin_2 PF00451.19 KXX73059.1 - 7.4 7.0 5.6 51 4.3 0.2 3.0 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 FAD_binding_3 PF01494.19 KXX73060.1 - 1.5e-06 27.7 2.8 0.053 12.8 0.0 3.5 2 1 1 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 KXX73060.1 - 0.0024 18.4 1.5 0.0048 17.4 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX73060.1 - 0.0026 18.0 0.2 0.0075 16.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX73060.1 - 0.0032 16.8 0.1 0.007 15.6 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX73060.1 - 0.23 10.7 0.6 0.39 9.9 0.6 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC4_2 PF13923.6 KXX73061.1 - 5.3e-10 39.0 7.7 8.9e-10 38.3 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX73061.1 - 5.3e-09 35.8 3.7 8.2e-09 35.2 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX73061.1 - 8.5e-09 35.2 7.7 1.3e-08 34.5 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX73061.1 - 1.9e-07 30.9 6.0 2.9e-07 30.3 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXX73061.1 - 1.3e-06 28.6 8.9 2.1e-06 27.9 8.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXX73061.1 - 2.2e-05 24.7 5.5 4.6e-05 23.6 5.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXX73061.1 - 0.00021 21.1 7.6 0.00036 20.3 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXX73061.1 - 0.00074 19.5 6.9 0.0014 18.6 6.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXX73061.1 - 0.00083 19.5 8.1 0.0014 18.7 8.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 KXX73061.1 - 0.015 15.2 5.4 0.027 14.3 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 KXX73061.1 - 0.028 14.4 3.6 0.057 13.4 3.6 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 KXX73061.1 - 0.06 13.2 8.0 0.09 12.6 3.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KXX73061.1 - 0.07 12.8 4.8 0.28 10.9 0.8 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KXX73061.1 - 0.2 11.7 7.3 1.6 8.8 7.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Trm112p PF03966.16 KXX73061.1 - 0.34 11.5 0.1 0.34 11.5 0.1 1.9 2 0 0 2 2 2 0 Trm112p-like protein Pkinase PF00069.25 KXX73062.1 - 9.2e-28 97.3 0.0 8.9e-27 94.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73062.1 - 3.1e-06 26.7 0.1 0.00071 18.9 0.0 2.7 4 0 0 4 4 4 2 Protein tyrosine kinase Brr6_like_C_C PF10104.9 KXX73065.1 - 4.7e-37 126.7 0.4 6e-37 126.4 0.4 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Nairovirus_M PF07948.11 KXX73065.1 - 0.28 9.4 0.0 0.37 8.9 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Pkinase PF00069.25 KXX73066.1 - 1e-42 146.4 0.1 8.7e-24 84.3 0.2 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73066.1 - 5.8e-15 55.3 0.4 2.2e-10 40.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX73066.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Med26 PF08711.11 KXX73067.1 - 1.1e-11 44.5 0.0 2.6e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4079 PF13301.6 KXX73068.1 - 0.21 11.7 0.2 0.21 11.7 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) KR PF08659.10 KXX73069.1 - 3.7e-09 36.7 0.3 6e-09 36.1 0.3 1.4 1 0 0 1 1 1 1 KR domain PUF PF00806.19 KXX73073.1 - 1.4e-53 175.7 3.2 1.4e-08 33.9 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat WD40 PF00400.32 KXX73074.1 - 6.3e-18 64.8 12.2 0.00024 21.8 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX73074.1 - 3e-09 37.1 0.1 0.016 15.5 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KXX73074.1 - 0.03 14.1 0.1 0.29 10.8 0.0 2.5 3 0 0 3 3 3 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KXX73074.1 - 0.031 13.2 2.9 15 4.4 0.1 3.7 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SARS_X4 PF08779.10 KXX73074.1 - 0.17 12.1 0.1 22 5.4 0.0 2.7 2 0 0 2 2 2 0 SARS coronavirus X4 like PQQ PF01011.21 KXX73074.1 - 0.17 11.9 3.0 5.2 7.2 0.2 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat Gcd10p PF04189.13 KXX73074.1 - 0.24 10.5 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Gcd10p family Asp PF00026.23 KXX73075.1 - 1.4e-70 238.2 0.0 1.8e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX73075.1 - 4.8e-15 56.2 0.4 3.5e-11 43.6 0.6 3.2 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXX73075.1 - 8.1e-08 32.8 0.5 0.15 12.7 0.1 3.9 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.6 KXX73075.1 - 0.00034 20.4 0.0 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KXX73075.1 - 0.0024 18.4 0.2 2.9 8.5 0.0 3.6 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease ATP-synt_C PF00137.21 KXX73076.1 - 8e-29 99.8 29.1 1.1e-20 73.7 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 KXX73076.1 - 0.054 13.2 0.5 9.2 6.0 0.1 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain SH PF01445.17 KXX73076.1 - 0.3 11.1 1.6 5.1 7.1 0.5 2.2 2 0 0 2 2 2 0 Viral small hydrophobic protein Pep3_Vps18 PF05131.14 KXX73077.1 - 2.5e-47 160.4 0.0 8.7e-47 158.7 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KXX73077.1 - 2.2e-11 43.8 2.1 5.5e-08 32.8 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 KXX73077.1 - 0.00076 19.1 0.3 0.0017 17.9 0.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KXX73077.1 - 0.0035 17.1 0.7 0.0096 15.7 0.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX73077.1 - 0.0052 16.7 1.6 0.0052 16.7 1.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXX73077.1 - 0.0077 16.0 1.9 0.0077 16.0 1.9 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KXX73077.1 - 0.024 14.9 0.2 0.065 13.5 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXX73077.1 - 0.026 14.8 1.4 0.079 13.3 1.4 1.9 1 0 0 1 1 1 0 Ring finger domain Vps39_2 PF10367.9 KXX73077.1 - 0.043 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.9 KXX73077.1 - 0.053 13.8 0.4 0.23 11.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DinB_2 PF12867.7 KXX73077.1 - 0.082 13.4 0.3 3.9 8.0 0.0 3.1 3 1 0 3 3 2 0 DinB superfamily ChAPs PF09295.10 KXX73077.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Alk_phosphatase PF00245.20 KXX73077.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase TPR_7 PF13176.6 KXX73077.1 - 0.15 12.1 0.0 48 4.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3H2C3 PF17122.5 KXX73077.1 - 1 9.5 5.1 0.25 11.4 1.2 2.0 2 0 0 2 2 2 0 Zinc-finger zf-RING_UBOX PF13445.6 KXX73077.1 - 1.2 9.2 5.7 0.098 12.7 0.6 1.8 2 0 0 2 2 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KXX73077.1 - 3.9 7.4 5.2 0.87 9.5 1.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF676 PF05057.14 KXX73079.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXX73079.1 - 0.0053 16.5 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_30 PF13604.6 KXX73079.1 - 0.0087 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXX73079.1 - 0.024 14.4 0.0 0.099 12.4 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KXX73079.1 - 0.027 14.8 0.0 0.086 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXX73079.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXX73079.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KXX73079.1 - 0.1 13.1 0.0 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXX73079.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KXX73079.1 - 0.14 12.7 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KXX73079.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 KXX73079.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KXX73079.1 - 0.18 12.2 0.1 0.38 11.2 0.1 1.6 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 KXX73079.1 - 0.19 11.8 0.1 0.45 10.6 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Acetyltransf_7 PF13508.7 KXX73080.1 - 1.8e-07 31.5 0.7 7.5e-07 29.5 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX73080.1 - 1.3e-05 25.4 0.4 3.5e-05 24.0 0.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX73080.1 - 0.00088 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX73080.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 KXX73080.1 - 0.14 12.9 0.2 0.2 12.3 0.2 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.22 KXX73083.1 - 1.3e-60 205.5 0.0 1.7e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.6 KXX73084.1 - 2.6e-19 69.3 1.4 2.6e-19 69.3 1.4 2.8 4 0 0 4 4 4 1 Membrane bound O-acyl transferase family OrsD PF12013.8 KXX73085.1 - 1.3e-06 28.8 0.0 2.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D CENP-B_dimeris PF09026.10 KXX73085.1 - 0.1 13.0 3.7 0.21 12.0 3.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Helicase_C PF00271.31 KXX73086.1 - 4.9e-12 46.2 0.0 8.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX73086.1 - 0.00018 21.3 0.0 0.14 11.9 0.0 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KXX73086.1 - 0.011 16.4 0.0 0.031 15.0 0.0 1.7 1 0 0 1 1 1 0 RecQ zinc-binding DUF456 PF04306.13 KXX73086.1 - 0.29 11.4 8.2 0.12 12.6 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 KXX73086.1 - 0.84 9.4 36.5 1.6 8.5 33.5 2.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF1269 PF06897.12 KXX73086.1 - 2.8 8.3 11.4 76 3.7 9.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 KXX73086.1 - 4.9 7.1 38.0 14 5.6 0.0 3.8 2 1 1 3 3 3 0 Glycine zipper 2TM domain Ank_2 PF12796.7 KXX73089.1 - 1.5e-57 192.2 0.0 3.6e-15 56.3 0.0 5.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXX73089.1 - 2.5e-46 154.1 0.0 0.00018 21.8 0.0 9.0 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 KXX73089.1 - 3.9e-45 151.7 0.0 1.3e-10 41.6 0.0 6.2 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73089.1 - 4.6e-45 146.4 0.0 0.00043 20.5 0.0 8.9 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KXX73089.1 - 7.6e-34 115.3 0.0 8.5e-07 29.1 0.0 7.0 5 2 3 8 8 8 6 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXX73089.1 - 3.8e-09 37.1 0.0 1.3e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KXX73089.1 - 5.4e-07 29.1 0.0 5.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain TPR_12 PF13424.6 KXX73089.1 - 3.2e-05 24.1 0.6 0.097 13.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat HTH_18 PF12833.7 KXX73089.1 - 0.00014 22.1 0.2 22 5.4 0.0 6.9 1 1 7 8 8 8 0 Helix-turn-helix domain TPR_8 PF13181.6 KXX73089.1 - 0.00034 20.6 0.2 0.35 11.2 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ATPase_2 PF01637.18 KXX73089.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_2 PF07719.17 KXX73089.1 - 0.016 15.2 1.8 4.4 7.7 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXX73089.1 - 0.058 13.2 0.3 12 5.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX73089.1 - 0.06 14.0 4.6 1.4 9.7 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX73089.1 - 0.068 14.0 0.4 35 5.6 0.2 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FAT PF02259.23 KXX73089.1 - 0.076 12.2 0.2 0.34 10.1 0.1 1.9 2 0 0 2 2 2 0 FAT domain TPR_7 PF13176.6 KXX73089.1 - 0.12 12.5 0.1 11 6.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RecA PF00154.21 KXX73089.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DPRP PF04244.13 KXX73089.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein Patatin PF01734.22 KXX73090.1 - 2.3e-13 50.8 0.2 2.5e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase DEAD PF00270.29 KXX73091.1 - 5.8e-49 166.2 0.0 1.9e-48 164.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX73091.1 - 9.2e-24 83.9 0.0 6.4e-23 81.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KXX73091.1 - 8.6e-23 80.4 1.4 2.6e-22 78.9 1.4 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain COPI_C PF06957.11 KXX73091.1 - 0.12 11.1 2.1 0.21 10.3 2.1 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF202 PF02656.15 KXX73092.1 - 0.00038 20.8 2.9 0.0024 18.3 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) EutH PF04346.12 KXX73092.1 - 0.01 15.1 0.7 0.011 14.9 0.7 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH UCR_Fe-S_N PF10399.9 KXX73092.1 - 0.011 15.1 0.1 0.011 15.1 0.1 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Tetraspanin PF00335.20 KXX73092.1 - 0.38 10.4 3.7 0.17 11.6 1.7 1.3 2 0 0 2 2 2 0 Tetraspanin family DUF3180 PF11377.8 KXX73092.1 - 0.59 10.3 7.4 0.75 9.9 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) DnaJ PF00226.31 KXX73094.1 - 4.6e-15 55.5 0.9 1e-14 54.4 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain Afi1 PF07792.12 KXX73094.1 - 0.29 11.6 7.3 0.071 13.6 3.7 1.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking IBR PF01485.21 KXX73095.1 - 3.4e-12 46.4 40.6 3.4e-09 36.8 8.7 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Arm PF00514.23 KXX73096.1 - 0.0027 17.7 0.8 0.44 10.7 0.2 3.2 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat CD99L2 PF12301.8 KXX73096.1 - 0.15 12.3 4.5 0.33 11.2 4.5 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 Fungal_trans PF04082.18 KXX73097.1 - 6.8e-15 54.8 0.1 1.1e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXX73097.1 - 3.4e-06 27.2 8.7 3.7e-05 24.0 2.2 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 KXX73097.1 - 0.0017 18.6 5.5 0.0034 17.6 5.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KXX73097.1 - 0.2 12.2 14.9 0.39 11.3 7.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX73097.1 - 0.63 11.0 23.4 0.066 14.1 5.8 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX73097.1 - 0.88 9.9 4.2 9.2 6.7 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GDI PF00996.18 KXX73098.1 - 4.9e-151 503.1 0.0 6e-151 502.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KXX73098.1 - 0.0057 16.9 0.0 0.054 13.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXX73098.1 - 0.058 13.9 0.4 0.57 10.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Erythro_esteras PF05139.14 KXX73098.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Erythromycin esterase MRP-L47 PF06984.13 KXX73099.1 - 5.8e-25 87.2 0.6 9.2e-25 86.6 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4092 PF13322.6 KXX73103.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) C2 PF00168.30 KXX73104.1 - 2e-09 37.7 0.0 3.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF2076 PF09849.9 KXX73104.1 - 3.9 7.4 8.2 0.56 10.2 4.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.25 KXX73106.1 - 3e-66 223.5 0.0 4.2e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73106.1 - 2.6e-41 141.6 0.0 3.8e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX73106.1 - 3.5e-08 33.1 0.0 1.6e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXX73106.1 - 1.7e-05 23.9 0.1 1.7e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXX73106.1 - 0.062 12.7 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferlin_C PF16165.5 KXX73106.1 - 0.089 12.7 0.2 0.089 12.7 0.2 1.8 2 0 0 2 2 2 0 Ferlin C-terminus APH PF01636.23 KXX73106.1 - 0.26 11.2 3.3 0.94 9.4 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXX73106.1 - 5.8 6.5 4.9 0.68 9.5 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Proteasome PF00227.26 KXX73107.1 - 3e-48 163.9 0.1 3.4e-48 163.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Flavodoxin_1 PF00258.25 KXX73107.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin Evr1_Alr PF04777.13 KXX73108.1 - 5.8e-28 97.3 0.0 1e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Abhydrolase_4 PF08386.10 KXX73109.1 - 2.9e-22 78.7 0.0 5.1e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXX73109.1 - 4e-10 39.8 0.0 5.9e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Retro_M PF02813.14 KXX73109.1 - 0.13 12.7 0.0 75 3.8 0.1 3.2 3 0 0 3 3 3 0 Retroviral M domain HD PF01966.22 KXX73110.1 - 9.8e-06 25.8 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 HD domain DUF2014 PF09427.10 KXX73111.1 - 2.2e-113 378.0 8.1 3.2e-113 377.5 8.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KXX73111.1 - 9.9e-17 60.7 0.9 2e-16 59.7 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain hNIFK_binding PF12196.8 KXX73111.1 - 0.32 10.5 2.9 0.96 9.0 2.9 1.9 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK FAD_binding_4 PF01565.23 KXX73112.1 - 2e-22 79.5 5.2 7e-22 77.7 3.2 2.6 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 KXX73112.1 - 0.0016 18.5 0.1 0.0048 17.0 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like NmrA PF05368.13 KXX73113.1 - 5.6e-35 121.0 0.0 7e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX73113.1 - 1.5e-22 80.4 0.0 3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX73113.1 - 9.8e-10 38.3 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX73113.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KXX73113.1 - 0.011 16.3 0.0 0.034 14.7 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KXX73113.1 - 0.058 13.6 0.3 4.4 7.6 0.0 2.4 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PALP PF00291.25 KXX73113.1 - 0.06 12.8 0.2 0.089 12.2 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme p450 PF00067.22 KXX73114.1 - 1.2e-33 116.6 0.0 1.7e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KXX73115.1 - 2e-09 37.2 0.5 5.7e-09 35.7 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX73115.1 - 9e-07 28.6 2.0 9e-07 28.6 2.0 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KXX73115.1 - 0.03 14.2 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 F-box Cys_rich_VLP PF14194.6 KXX73116.1 - 0.049 13.7 1.1 0.089 12.9 1.1 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP AIM24 PF01987.17 KXX73117.1 - 2.9e-51 174.1 0.1 3.6e-51 173.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Androgen_recep PF02166.16 KXX73117.1 - 0.0032 16.4 0.5 0.0032 16.4 0.5 2.3 1 1 1 2 2 2 1 Androgen receptor Ndc1_Nup PF09531.10 KXX73117.1 - 0.0039 15.9 3.3 0.0047 15.7 3.3 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 KXX73117.1 - 8.1 6.3 29.2 11 5.9 29.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 KXX73118.1 - 0.0027 17.4 1.6 0.0029 17.3 1.6 1.2 1 0 0 1 1 1 1 FAM176 family Exotox-A_target PF09102.10 KXX73118.1 - 0.052 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A, targeting BUD22 PF09073.10 KXX73118.1 - 0.055 12.8 5.0 0.056 12.8 5.0 1.0 1 0 0 1 1 1 0 BUD22 Radial_spoke PF04712.12 KXX73118.1 - 0.12 11.3 4.5 0.11 11.4 4.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein RXT2_N PF08595.11 KXX73118.1 - 0.13 12.3 7.2 0.17 11.9 7.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 KXX73118.1 - 0.26 9.4 10.2 0.28 9.4 10.2 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 KXX73118.1 - 0.38 10.5 7.5 0.46 10.2 7.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 KXX73118.1 - 0.53 10.2 4.0 0.64 9.9 4.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4820 PF16091.5 KXX73118.1 - 0.68 9.3 2.7 0.83 9.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TRAP_alpha PF03896.16 KXX73118.1 - 0.91 8.7 5.5 1.1 8.4 5.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.18 KXX73118.1 - 1.1 9.1 6.7 1.4 8.8 6.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2457 PF10446.9 KXX73118.1 - 1.5 7.9 16.9 1.7 7.7 16.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 KXX73118.1 - 1.6 9.2 18.8 2.4 8.6 18.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFB6 PF17110.5 KXX73118.1 - 1.8 8.3 7.1 2.2 8.0 7.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Astro_capsid_p PF12226.8 KXX73118.1 - 2 7.5 12.4 2.1 7.4 12.4 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 KXX73118.1 - 2.2 8.0 14.2 2.6 7.7 14.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KXX73118.1 - 2.3 7.5 16.7 3 7.1 16.7 1.1 1 0 0 1 1 1 0 NOA36 protein Cytomega_UL84 PF06284.11 KXX73118.1 - 2.8 6.3 5.2 2.9 6.3 5.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SDA1 PF05285.12 KXX73118.1 - 3 7.2 13.1 3.5 6.9 13.1 1.0 1 0 0 1 1 1 0 SDA1 HTH_Tnp_Tc5 PF03221.16 KXX73119.1 - 1e-09 38.3 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PIF1 PF05970.14 KXX73120.1 - 8.3e-59 199.6 0.3 3.8e-46 157.9 0.0 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KXX73120.1 - 2.6e-22 79.5 0.0 5.3e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX73120.1 - 5.9e-12 46.1 0.0 1.4e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX73120.1 - 1.7e-06 28.3 0.0 6.2e-06 26.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KXX73120.1 - 5.9e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 KXX73120.1 - 0.00011 22.6 0.0 0.00034 21.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX73120.1 - 0.00027 21.4 0.0 0.00073 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 KXX73120.1 - 0.0003 18.9 0.1 0.0015 16.5 0.0 1.8 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KXX73120.1 - 0.00038 20.2 0.1 0.00085 19.1 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 KXX73120.1 - 0.0012 19.3 0.8 0.008 16.7 0.0 2.4 1 1 1 2 2 2 1 ABC transporter RNA_helicase PF00910.22 KXX73120.1 - 0.0051 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 KXX73120.1 - 0.0066 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KXX73120.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KXX73120.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KXX73120.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 KXX73120.1 - 0.018 14.5 0.1 0.051 13.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 KXX73120.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.8 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KXX73120.1 - 0.028 14.3 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 KXX73120.1 - 0.044 13.7 0.0 0.099 12.5 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 KXX73120.1 - 0.048 12.5 0.1 0.083 11.8 0.1 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_14 PF13173.6 KXX73120.1 - 0.049 13.7 0.0 0.17 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXX73120.1 - 0.06 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KXX73120.1 - 0.061 12.5 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 KXX73120.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KXX73120.1 - 0.074 12.8 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein TEX33 PF15400.6 KXX73120.1 - 0.077 13.5 0.4 0.2 12.2 0.4 1.7 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family DUF2075 PF09848.9 KXX73120.1 - 0.092 12.0 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KXX73120.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KXX73120.1 - 0.13 12.3 0.5 1.4 8.9 0.1 2.6 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) SH3_13 PF18335.1 KXX73120.1 - 0.18 11.7 0.0 0.51 10.2 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain YjeF_N PF03853.15 KXX73121.1 - 3e-41 141.1 0.0 4.7e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KXX73121.1 - 5.2e-13 49.8 0.2 1.6e-12 48.2 0.2 1.8 1 0 0 1 1 1 1 FDF domain DUF3181 PF11378.8 KXX73121.1 - 0.18 12.1 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) Abhydrolase_1 PF00561.20 KXX73123.1 - 1.2e-12 48.1 0.0 1.4e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX73123.1 - 1.7e-11 45.2 0.6 2e-11 44.9 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX73123.1 - 4.7e-08 32.6 0.0 5.3e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KXX73123.1 - 0.02 13.8 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme EHN PF06441.12 KXX73123.1 - 0.19 12.1 0.3 0.35 11.3 0.1 1.6 2 0 0 2 2 2 0 Epoxide hydrolase N terminus p450 PF00067.22 KXX73124.1 - 2.5e-41 141.9 0.0 3.2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KXX73125.1 - 3.7e-22 78.7 0.0 4.9e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73125.1 - 1.2e-12 47.9 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73125.1 - 1.4e-06 28.4 0.0 2.7e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXX73125.1 - 1.8e-06 27.6 0.1 1.8e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX73125.1 - 0.00024 20.6 0.4 0.00035 20.1 0.1 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXX73125.1 - 0.0022 17.9 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding TrkA_N PF02254.18 KXX73125.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DAHP_snth_FXD PF18152.1 KXX73125.1 - 0.13 12.1 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain DUF3425 PF11905.8 KXX73126.1 - 9.7e-12 45.0 0.0 2.8e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Pkinase PF00069.25 KXX73127.1 - 1.9e-25 89.8 0.0 2.7e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73127.1 - 1.6e-12 47.3 0.0 2.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX73127.1 - 0.00042 19.2 0.0 0.00059 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXX73127.1 - 0.00046 19.6 0.0 0.00071 19.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX73127.1 - 0.0041 17.1 0.1 0.0074 16.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXX73127.1 - 0.044 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Methyltransf_23 PF13489.6 KXX73128.1 - 1.6e-22 80.1 0.0 3.8e-22 78.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX73128.1 - 3.5e-14 53.2 0.0 7.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX73128.1 - 9.4e-14 51.9 0.0 2.4e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX73128.1 - 1.9e-07 31.0 0.0 0.0066 16.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXX73128.1 - 3.6e-07 30.9 0.0 2.7e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX73128.1 - 0.00019 20.9 0.0 0.005 16.2 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX73128.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXX73128.1 - 0.012 15.0 0.0 0.035 13.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 KXX73128.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXX73128.1 - 0.037 13.4 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXX73128.1 - 0.042 13.2 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KXX73128.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CorA PF01544.18 KXX73129.1 - 4.4e-06 26.2 0.2 9.4e-06 25.1 0.2 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NitrOD1 PF18549.1 KXX73129.1 - 0.08 12.9 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 VBS PF08913.10 KXX73129.1 - 0.17 12.3 0.4 0.49 10.9 0.4 1.7 1 0 0 1 1 1 0 Vinculin Binding Site CCDC53 PF10152.9 KXX73130.1 - 0.017 15.6 0.7 0.035 14.5 0.7 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2076 PF09849.9 KXX73130.1 - 0.17 11.9 3.9 0.25 11.4 3.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 KXX73130.1 - 1.1 9.8 7.9 2.1 9.0 7.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_11 PF08241.12 KXX73131.1 - 8.5e-13 48.8 0.0 8.4e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX73131.1 - 1e-11 45.4 0.0 4.1e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX73131.1 - 6e-09 35.6 0.0 9.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXX73131.1 - 2.7e-07 31.2 0.0 6.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX73131.1 - 6.5e-06 26.0 0.0 9.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX73131.1 - 0.0052 16.6 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Se-cys_synth_N PF12390.8 KXX73131.1 - 0.022 14.9 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Ifi-6-16 PF06140.13 KXX73132.1 - 1.1e-10 41.3 27.1 1.1e-10 41.3 27.1 2.3 1 1 1 2 2 2 1 Interferon-induced 6-16 family DUF883 PF05957.13 KXX73132.1 - 3.4 8.3 11.1 0.073 13.7 4.2 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Cyclin_N PF00134.23 KXX73133.1 - 2.2e-08 33.9 0.0 4.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Receptor_IA-2 PF11548.8 KXX73133.1 - 0.0066 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase receptor IA-2 Spy1 PF11357.8 KXX73133.1 - 0.092 13.0 0.3 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Cell cycle regulatory protein CECR6_TMEM121 PF14997.6 KXX73133.1 - 0.18 11.6 0.2 0.28 11.0 0.2 1.2 1 0 0 1 1 1 0 CECR6/TMEM121 family WD40 PF00400.32 KXX73135.1 - 0.018 15.9 0.6 0.066 14.1 0.0 2.3 2 2 1 3 3 3 0 WD domain, G-beta repeat HET PF06985.11 KXX73136.1 - 1e-22 81.1 0.0 2.7e-22 79.7 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 KXX73137.1 - 2.4e-06 27.5 0.1 5.2e-05 23.2 0.1 2.9 2 1 0 2 2 2 1 NACHT domain DUF676 PF05057.14 KXX73137.1 - 0.0017 17.9 0.0 0.0061 16.1 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) RNA_helicase PF00910.22 KXX73137.1 - 0.0038 17.6 0.0 0.0088 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KXX73137.1 - 0.004 16.4 0.0 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain PGAP1 PF07819.13 KXX73137.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AAA_22 PF13401.6 KXX73137.1 - 0.01 16.1 0.0 0.065 13.5 0.0 2.4 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KXX73137.1 - 0.012 16.1 0.0 0.031 14.6 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KXX73137.1 - 0.012 15.5 0.0 0.085 12.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Abhydrolase_6 PF12697.7 KXX73137.1 - 0.015 15.9 0.0 0.053 14.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA_19 PF13245.6 KXX73137.1 - 0.025 14.9 0.0 0.061 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXX73137.1 - 0.047 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXX73137.1 - 0.078 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX73137.1 - 0.088 12.5 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain UBA_2 PF08587.11 KXX73137.1 - 0.092 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) PPV_E1_C PF00519.17 KXX73137.1 - 0.11 11.3 0.0 0.33 9.7 0.0 1.6 2 0 0 2 2 2 0 Papillomavirus helicase AAA_14 PF13173.6 KXX73137.1 - 0.13 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KXX73138.1 - 3.4e-65 220.0 0.0 4.1e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73138.1 - 1.1e-25 90.4 0.0 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX73138.1 - 1.3e-06 28.0 0.0 7.8e-06 25.4 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KXX73138.1 - 0.0011 18.9 0.2 0.0074 16.2 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 KXX73138.1 - 0.0063 16.7 0.2 0.01 16.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Kdo PF06293.14 KXX73138.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXX73138.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KXX73138.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PAC4 PF16093.5 KXX73139.1 - 1.7e-23 82.6 0.0 2.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Speriolin_N PF15058.6 KXX73139.1 - 0.033 14.3 2.7 0.34 11.0 2.7 2.0 1 1 0 1 1 1 0 Speriolin N terminus Zn_clus PF00172.18 KXX73140.1 - 2.1e-08 34.1 11.8 3.3e-08 33.5 11.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX73140.1 - 2.9e-07 29.6 0.1 5.5e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Titin_Ig-rpts PF06582.12 KXX73140.1 - 0.35 10.8 2.0 0.72 9.8 2.0 1.5 1 0 0 1 1 1 0 Titin repeat HEAT_EZ PF13513.6 KXX73141.1 - 1.9e-28 98.4 15.7 4.1e-17 62.3 0.0 11.1 11 3 1 12 12 12 2 HEAT-like repeat HEAT PF02985.22 KXX73141.1 - 1.5e-21 74.6 15.6 8.2e-06 25.7 0.0 10.3 12 0 0 12 12 10 5 HEAT repeat HEAT_2 PF13646.6 KXX73141.1 - 2.9e-18 66.0 0.1 2.1e-05 24.8 0.0 7.4 4 3 2 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KXX73141.1 - 9.1e-08 32.3 0.0 0.64 10.0 0.0 4.8 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXX73141.1 - 1.4e-07 32.0 0.0 0.3 11.7 0.0 6.1 5 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KXX73141.1 - 8.7e-07 28.4 7.1 0.06 12.5 0.0 5.4 5 2 1 6 6 6 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KXX73141.1 - 5.2e-06 26.3 4.9 1.3e-05 25.0 0.6 4.0 4 1 0 4 4 4 1 Importin-beta N-terminal domain RIX1 PF08167.12 KXX73141.1 - 0.00014 21.7 0.2 4.8 6.9 0.0 5.6 7 1 0 7 7 7 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 KXX73141.1 - 0.00046 19.8 0.0 5.1 6.6 0.0 5.9 8 1 0 8 8 8 1 CLASP N terminal RTP1_C1 PF10363.9 KXX73141.1 - 0.0013 18.9 0.0 0.097 12.9 0.0 3.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 KXX73141.1 - 0.026 14.4 0.1 1.4 8.9 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) Arm PF00514.23 KXX73141.1 - 0.054 13.6 6.3 0.87 9.7 0.0 5.4 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KXX73141.1 - 0.084 13.2 0.0 15 6.0 0.0 3.7 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain HEAT_PBS PF03130.16 KXX73141.1 - 0.12 13.1 5.4 3.7 8.5 0.0 5.0 5 0 0 5 5 2 0 PBS lyase HEAT-like repeat Dynamin_N PF00350.23 KXX73142.1 - 1.1e-36 126.5 0.1 2e-36 125.6 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXX73142.1 - 5.6e-23 81.6 0.0 3e-22 79.2 0.0 2.0 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KXX73142.1 - 8.4e-05 22.6 0.0 0.00044 20.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Med9 PF07544.13 KXX73142.1 - 0.0014 18.7 1.6 0.025 14.6 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 GED PF02212.18 KXX73142.1 - 0.0033 17.5 0.4 0.021 14.9 0.1 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.27 KXX73142.1 - 0.056 14.0 0.0 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_15 PF13175.6 KXX73142.1 - 0.085 12.6 0.2 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KXX73142.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KXX73142.1 - 0.2 11.9 0.0 5.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Snapin_Pallidin PF14712.6 KXX73142.1 - 0.46 10.9 2.2 11 6.5 0.0 3.4 4 0 0 4 4 4 0 Snapin/Pallidin Aldolase_II PF00596.21 KXX73144.1 - 4.9e-32 111.4 0.0 6.1e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAD_binding_3 PF01494.19 KXX73145.1 - 3.6e-14 52.8 0.0 5.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_C PF05199.13 KXX73146.1 - 6.9e-32 110.9 0.0 1.1e-31 110.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXX73146.1 - 2.3e-29 102.7 0.0 7.1e-25 88.0 0.0 3.4 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KXX73146.1 - 0.00035 20.7 0.1 0.0012 19.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX73146.1 - 0.0061 15.7 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX73146.1 - 0.0065 15.7 0.1 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX73146.1 - 0.093 12.0 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXX73146.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KXX73146.1 - 0.15 11.4 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 KXX73146.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PH_8 PF15409.6 KXX73147.1 - 0.035 14.4 0.7 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1232 PF06803.12 KXX73147.1 - 0.073 12.9 1.9 0.27 11.1 1.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) ADH_zinc_N PF00107.26 KXX73148.1 - 7e-16 58.4 0.1 1.2e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX73148.1 - 6.2e-15 56.4 0.0 1.1e-14 55.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX73148.1 - 0.00019 21.2 0.2 0.0023 17.8 0.0 2.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Formyl_trans_N PF00551.19 KXX73149.1 - 2e-39 135.2 0.0 2.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Sas10 PF09368.10 KXX73150.1 - 5.5e-31 106.9 6.9 5.5e-31 106.9 6.9 3.3 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KXX73150.1 - 5.1e-11 43.0 0.2 4.1e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF3106 PF11304.8 KXX73150.1 - 0.95 10.0 14.9 0.41 11.1 7.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) adh_short PF00106.25 KXX73151.1 - 5.6e-28 97.7 0.0 7.2e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73151.1 - 1.6e-17 63.9 0.0 2.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73151.1 - 5.7e-08 32.9 0.2 1.3e-07 31.8 0.1 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 KXX73151.1 - 0.016 15.0 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2474 PF10617.9 KXX73151.1 - 0.046 13.6 0.4 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) THF_DHG_CYH_C PF02882.19 KXX73151.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Myc_N PF01056.18 KXX73152.1 - 0.26 11.1 4.6 0.46 10.3 4.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region WD40 PF00400.32 KXX73153.1 - 1.8e-22 79.2 2.2 2.5e-10 40.8 0.0 3.7 4 0 0 4 4 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXX73153.1 - 6.7e-10 38.4 0.0 0.00064 18.8 0.0 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KXX73153.1 - 1.6e-08 34.7 0.1 3.4e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KXX73153.1 - 3.6e-08 33.6 0.0 0.0053 17.0 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KXX73153.1 - 4.6e-07 30.4 0.3 1.1e-06 29.1 0.3 1.7 1 0 0 1 1 1 1 AAA ATPase domain Helo_like_N PF17111.5 KXX73153.1 - 8.8e-07 28.5 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Nup160 PF11715.8 KXX73153.1 - 0.00022 20.0 0.3 0.19 10.3 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 KAP_NTPase PF07693.14 KXX73153.1 - 0.0055 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain Nbas_N PF15492.6 KXX73153.1 - 0.016 14.5 0.1 6 6.1 0.0 2.6 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal APS_kinase PF01583.20 KXX73153.1 - 0.031 14.2 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Gmad1 PF10647.9 KXX73153.1 - 0.06 13.1 1.2 1.4 8.6 0.1 2.1 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain NB-ARC PF00931.22 KXX73153.1 - 0.064 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PD40 PF07676.12 KXX73153.1 - 0.065 13.2 2.7 7.1 6.7 0.0 3.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat AAA_30 PF13604.6 KXX73153.1 - 0.068 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXX73153.1 - 0.079 13.4 0.0 0.25 11.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXX73153.1 - 0.088 13.3 0.0 0.35 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KXX73153.1 - 0.096 12.7 0.2 0.33 11.0 0.2 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KXX73153.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3716 PF12511.8 KXX73154.1 - 6e-16 58.2 8.3 1e-15 57.5 8.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AT_hook PF02178.19 KXX73154.1 - 1.2 9.3 4.5 10 6.4 0.5 2.5 2 0 0 2 2 2 0 AT hook motif TFIIA PF03153.13 KXX73154.1 - 6.1 6.7 9.0 10 6.0 9.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4419 PF14388.6 KXX73155.1 - 2.2e-71 240.8 0.0 5.9e-71 239.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) FAD_binding_4 PF01565.23 KXX73156.1 - 3.3e-20 72.2 1.0 6.9e-20 71.2 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX73156.1 - 7.1e-08 32.4 0.1 1.7e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Erg28 PF03694.13 KXX73157.1 - 8.5e-15 55.1 0.2 9.7e-15 54.9 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein NCBP3 PF10309.9 KXX73157.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Nuclear cap-binding protein subunit 3 GST_N PF02798.20 KXX73158.1 - 5e-11 42.8 0.0 8.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXX73158.1 - 4.1e-07 30.1 0.0 6.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX73158.1 - 2e-06 27.9 0.0 3.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXX73158.1 - 9.5e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXX73158.1 - 3.4e-05 24.0 0.0 6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXX73158.1 - 5.8e-05 23.4 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LMBR1 PF04791.16 KXX73159.1 - 0.015 14.2 0.1 0.016 14.2 0.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Gtr1_RagA PF04670.12 KXX73159.1 - 0.076 12.3 0.2 0.088 12.1 0.2 1.0 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KXX73160.1 - 2.9e-18 66.7 0.0 1.1e-15 58.3 0.0 3.2 3 0 0 3 3 2 1 ABC transporter ABC_membrane PF00664.23 KXX73160.1 - 1.1e-08 35.1 11.6 2.3e-08 34.0 5.3 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KXX73160.1 - 6.6e-06 25.7 0.4 0.023 14.1 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KXX73160.1 - 0.00023 20.3 0.0 0.00048 19.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_21 PF13304.6 KXX73160.1 - 0.00044 20.2 0.1 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXX73160.1 - 0.0025 18.1 0.1 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXX73160.1 - 0.005 17.0 0.2 3 8.1 0.3 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CAMSAP_CH PF11971.8 KXX73160.1 - 0.013 15.3 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 CAMSAP CH domain AAA_33 PF13671.6 KXX73160.1 - 0.023 14.9 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXX73160.1 - 0.025 14.0 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXX73160.1 - 0.026 14.0 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KXX73160.1 - 0.046 14.1 0.5 0.89 10.0 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KXX73160.1 - 0.11 12.4 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RsgA_GTPase PF03193.16 KXX73160.1 - 0.15 11.9 0.1 0.58 10.0 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase Ank_4 PF13637.6 KXX73161.1 - 2e-08 34.6 0.0 7.4e-05 23.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX73161.1 - 1.1e-07 32.0 0.1 0.038 14.5 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXX73161.1 - 2.7e-07 31.1 0.1 3.7e-05 24.2 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX73161.1 - 3.5e-07 30.4 0.0 0.00025 21.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73161.1 - 0.00021 21.4 0.0 0.38 11.4 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Rad51 PF08423.11 KXX73162.1 - 4.1e-11 42.6 0.0 1.9e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 KXX73162.1 - 0.00054 19.4 0.2 0.0013 18.2 0.1 1.6 2 0 0 2 2 2 1 KaiC RecA PF00154.21 KXX73162.1 - 0.0054 16.2 0.5 0.062 12.8 0.1 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KXX73162.1 - 0.026 13.9 0.1 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KXX73162.1 - 0.039 13.7 0.0 0.19 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXX73162.1 - 0.049 13.2 0.2 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain zf-H2C2_2 PF13465.6 KXX73163.1 - 4.2e-08 33.3 15.7 2.4e-05 24.6 3.4 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXX73163.1 - 9.1e-06 25.9 22.6 0.0014 19.0 5.8 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX73163.1 - 0.0035 18.1 15.9 0.092 13.6 1.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXX73163.1 - 0.0066 16.4 1.6 3 8.0 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX73163.1 - 0.14 12.5 3.1 0.31 11.4 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXX73163.1 - 0.33 11.6 0.2 0.33 11.6 0.2 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KXX73163.1 - 2.1 8.2 12.3 3 7.7 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain GWT1 PF06423.12 KXX73165.1 - 4.3e-44 150.3 1.9 1.2e-43 148.8 1.9 1.8 1 0 0 1 1 1 1 GWT1 DUF4818 PF16089.5 KXX73165.1 - 0.0022 18.4 0.0 0.0022 18.4 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4818) Pkinase PF00069.25 KXX73166.1 - 1.4e-58 198.4 0.0 8.5e-57 192.5 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73166.1 - 5.1e-33 114.4 0.0 2.3e-27 95.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXX73166.1 - 9e-07 28.5 0.0 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXX73166.1 - 1.3e-05 25.2 0.1 9.3e-05 22.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXX73166.1 - 0.0021 17.4 0.1 0.0042 16.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXX73166.1 - 0.012 14.6 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KXX73166.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXX73166.1 - 1.4 7.6 2.9 0.8 8.4 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Tuberculin PF12198.8 KXX73167.1 - 9.4 6.4 9.5 16 5.7 0.3 2.3 2 0 0 2 2 2 0 Theoretical tuberculin protein Arrestin_N PF00339.29 KXX73168.1 - 0.091 12.8 0.0 0.34 11.0 0.0 2.1 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain PAF-AH_p_II PF03403.13 KXX73169.1 - 4.2e-07 28.8 0.0 0.0036 15.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DUF2434 PF10361.9 KXX73170.1 - 2.7e-138 459.9 8.7 3.4e-138 459.5 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.9 KXX73171.1 - 1.3e-40 138.6 1.4 1.3e-40 138.6 1.4 1.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF4407 PF14362.6 KXX73171.1 - 0.017 14.5 0.8 0.033 13.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 KXX73171.1 - 0.042 13.6 0.6 0.12 12.1 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) SKA1 PF07160.12 KXX73171.1 - 0.057 13.3 0.6 0.12 12.2 0.6 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 GrpE PF01025.19 KXX73171.1 - 0.08 12.6 0.6 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 GrpE LPP PF04728.13 KXX73171.1 - 0.13 12.7 0.9 0.59 10.6 0.9 2.1 1 0 0 1 1 1 0 Lipoprotein leucine-zipper FapA PF03961.13 KXX73171.1 - 0.13 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 KXX73171.1 - 0.79 10.0 4.1 1.1 9.5 2.1 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Erf4 PF10256.9 KXX73172.1 - 0.011 15.8 0.0 0.075 13.1 0.0 2.1 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family VPS13_C PF16909.5 KXX73174.1 - 2.2 8.0 4.7 0.96 9.2 1.8 1.7 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Esterase PF00756.20 KXX73175.1 - 4e-08 33.2 0.0 5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXX73175.1 - 0.00024 20.6 0.1 0.00042 19.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXX73175.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AA_permease_2 PF13520.6 KXX73176.1 - 5.7e-39 134.2 39.7 1.1e-38 133.2 39.7 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX73176.1 - 6.4e-09 34.9 32.3 9.2e-06 24.5 8.1 2.3 2 0 0 2 2 2 2 Amino acid permease OST3_OST6 PF04756.13 KXX73176.1 - 0.64 9.3 5.8 1.6 8.0 0.6 2.3 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family EcsB PF05975.12 KXX73177.1 - 0.018 13.9 0.7 0.025 13.5 0.7 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB PilM PF07419.12 KXX73179.1 - 0.026 14.7 0.0 0.11 12.6 0.0 2.0 2 1 1 3 3 3 0 PilM zf-C2H2 PF00096.26 KXX73181.1 - 0.0071 16.7 10.3 0.032 14.7 0.2 4.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX73181.1 - 0.013 16.3 0.2 0.013 16.3 0.2 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KXX73181.1 - 0.028 14.9 2.0 3.4 8.2 0.3 2.9 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DHC PF09626.10 KXX73181.1 - 0.03 15.2 1.3 0.03 15.2 1.3 2.0 2 0 0 2 2 2 0 Dihaem cytochrome c DUF629 PF04780.12 KXX73181.1 - 0.28 9.7 1.4 0.48 8.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Ank_2 PF12796.7 KXX73183.1 - 3.6e-19 69.1 5.0 1.3e-09 38.5 0.6 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX73183.1 - 1.2e-10 41.4 0.1 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX73183.1 - 1.5e-08 34.7 1.8 0.068 13.6 0.2 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXX73183.1 - 8.9e-08 32.5 0.1 0.0099 16.4 0.0 3.6 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73183.1 - 1.8e-07 30.9 0.1 0.11 13.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat vWA-TerF-like PF10138.9 KXX73183.1 - 0.0019 18.4 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus PNP_UDP_1 PF01048.20 KXX73184.1 - 1.8e-05 24.1 0.1 0.00011 21.6 0.1 2.0 1 1 1 2 2 2 1 Phosphorylase superfamily Peripla_BP_3 PF13377.6 KXX73184.1 - 0.028 14.8 0.1 0.058 13.7 0.1 1.6 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Sugar_tr PF00083.24 KXX73185.1 - 3.6e-112 375.5 23.8 4.3e-112 375.3 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX73185.1 - 5.1e-25 88.2 31.5 1.9e-16 60.0 6.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXX73185.1 - 0.044 12.1 3.1 0.059 11.6 2.2 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M43 PF05572.13 KXX73186.1 - 4.9e-17 62.2 0.2 7.8e-17 61.6 0.2 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXX73186.1 - 4.9e-07 30.1 0.1 7.1e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXX73186.1 - 8.5e-07 29.5 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXX73186.1 - 0.0001 22.0 0.3 0.00019 21.1 0.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXX73186.1 - 0.0028 17.6 0.2 0.0043 17.0 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXX73186.1 - 0.03 14.2 0.1 0.088 12.6 0.1 1.4 1 1 0 1 1 1 0 Matrixin DUF4953 PF16313.5 KXX73186.1 - 0.045 13.0 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 KXX73186.1 - 0.059 13.0 0.2 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 KXX73186.1 - 0.12 12.4 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.8 KXX73186.1 - 0.21 10.1 0.5 0.29 9.7 0.5 1.1 1 0 0 1 1 1 0 Putative peptidase family Dioxygenase_C PF00775.21 KXX73188.1 - 5.9e-06 25.8 0.1 1.1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Aminotran_5 PF00266.19 KXX73190.1 - 8.8e-14 51.2 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXX73190.1 - 0.0029 16.8 0.0 0.025 13.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 KXX73190.1 - 0.065 11.9 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS AAL_decarboxy PF03306.13 KXX73192.1 - 8.7e-79 263.9 0.2 9.9e-79 263.7 0.2 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Ank_2 PF12796.7 KXX73195.1 - 1.8e-22 79.7 0.5 1.8e-08 34.9 0.1 4.6 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX73195.1 - 2.4e-19 69.4 0.5 3e-06 27.7 0.0 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73195.1 - 9.5e-19 65.5 2.5 0.026 15.1 0.0 7.8 7 1 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KXX73195.1 - 1.2e-13 50.8 0.9 0.093 13.2 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXX73195.1 - 2.3e-11 43.7 2.7 0.00017 21.8 0.1 5.3 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KXX73195.1 - 3e-07 30.0 7.4 3.9e-07 29.6 0.5 3.5 2 1 1 3 3 3 1 Fungal N-terminal domain of STAND proteins DUF4988 PF16378.5 KXX73195.1 - 0.0061 16.2 0.0 0.92 9.1 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function Prp19 PF08606.11 KXX73195.1 - 0.13 12.3 1.7 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Prp19/Pso4-like DUF1664 PF07889.12 KXX73195.1 - 0.18 11.8 1.0 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KXX73195.1 - 3.8 8.0 5.4 1.5 9.3 0.2 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fungal_trans PF04082.18 KXX73196.1 - 7e-17 61.3 2.0 1.8e-16 60.0 2.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXX73196.1 - 2.1e-07 31.0 7.7 0.0053 17.2 3.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX73196.1 - 2e-05 25.0 7.5 0.011 16.5 2.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXX73196.1 - 7.1e-05 23.0 12.3 0.00025 21.3 2.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXX73196.1 - 0.093 13.1 0.4 0.75 10.2 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding VHS PF00790.19 KXX73197.1 - 2e-38 131.4 0.2 4.6e-38 130.3 0.2 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KXX73197.1 - 1.1e-15 57.0 0.0 2.1e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXX73197.1 - 2.8e-15 55.7 0.0 5.4e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXX73197.1 - 1.4e-14 53.6 0.1 2.7e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KXX73197.1 - 3.8e-10 39.9 3.7 4.8e-10 39.6 1.7 2.1 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KXX73197.1 - 0.0067 16.3 4.6 0.017 15.0 4.6 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif UNC45-central PF11701.8 KXX73197.1 - 0.31 11.0 1.9 0.35 10.8 0.2 1.8 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Pectate_lyase_3 PF12708.7 KXX73198.1 - 1.3e-94 316.0 14.6 2.1e-83 279.4 2.2 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXX73198.1 - 3.6e-05 23.4 0.9 0.016 14.9 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PhyH PF05721.13 KXX73199.1 - 1.1e-10 42.1 0.0 4.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) SET PF00856.28 KXX73200.1 - 8.2e-16 58.8 1.1 8.2e-16 58.8 1.1 2.8 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KXX73200.1 - 2e-06 27.7 6.3 4.9e-06 26.5 6.3 1.7 1 0 0 1 1 1 1 AWS domain PAXIP1_C PF15364.6 KXX73200.1 - 0.18 12.1 2.6 0.68 10.2 2.6 2.0 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DHHC PF01529.20 KXX73201.1 - 4.4e-27 94.8 1.1 4.4e-27 94.8 1.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase PBP1_TM PF14812.6 KXX73202.1 - 0.016 15.6 1.2 0.026 14.9 1.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 KXX73202.1 - 0.028 14.2 2.7 0.034 13.9 2.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KXX73202.1 - 0.056 12.8 1.3 0.066 12.5 1.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3245 PF11595.8 KXX73202.1 - 0.073 13.5 1.6 0.097 13.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) CENP-B_dimeris PF09026.10 KXX73202.1 - 0.12 12.8 4.5 0.18 12.2 4.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2423 PF10338.9 KXX73203.1 - 1.3e-06 28.5 1.5 1.3e-06 28.5 1.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) SPOUT_MTase PF02590.17 KXX73203.1 - 0.0046 16.9 0.1 0.005 16.8 0.1 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase Phosphodiest PF01663.22 KXX73204.1 - 6.7e-13 49.0 2.5 1.1e-10 41.7 2.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXX73204.1 - 6.1e-06 25.8 0.0 0.00036 20.0 0.0 2.2 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KXX73204.1 - 0.00017 21.0 0.0 0.00045 19.6 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily Flavi_NS4A PF01350.17 KXX73204.1 - 0.21 11.5 3.6 0.087 12.8 0.5 1.9 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF883 PF05957.13 KXX73204.1 - 0.3 11.7 1.1 4.2 8.1 0.4 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Auxin_canalis PF05703.11 KXX73204.1 - 4 7.3 4.8 22 4.8 0.1 2.2 2 0 0 2 2 2 0 Auxin canalisation PINIT PF14324.6 KXX73205.1 - 3.8e-44 150.6 0.2 7.8e-44 149.5 0.0 1.7 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 KXX73205.1 - 2.6e-22 78.3 6.3 4.6e-22 77.5 6.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 KXX73205.1 - 6.1e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 KXX73205.1 - 2.5e-06 27.2 2.1 5e-06 26.2 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 KXX73205.1 - 0.0056 16.7 2.0 0.014 15.5 1.2 2.0 1 1 1 2 2 2 1 Sec23/Sec24 zinc finger DUF3880 PF12996.7 KXX73205.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) zf-C3HC4_4 PF15227.6 KXX73205.1 - 0.27 11.4 5.6 0.51 10.6 5.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KXX73205.1 - 0.47 10.8 5.2 0.85 10.0 5.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KXX73205.1 - 0.52 10.3 4.5 1 9.4 4.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXX73205.1 - 1.1 9.3 4.8 0.8 9.8 1.2 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXX73205.1 - 1.8 8.5 5.7 3.4 7.6 5.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TRAPP PF04051.16 KXX73206.1 - 5e-47 159.3 0.0 6.5e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.8 KXX73206.1 - 0.11 12.9 0.2 0.52 10.7 0.0 1.9 2 0 0 2 2 2 0 Alpha helical Porin B Ribosomal_L28e PF01778.17 KXX73207.1 - 5.5e-34 117.4 0.1 7.9e-34 116.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family FA_hydroxylase PF04116.13 KXX73208.1 - 6.3e-26 91.3 22.2 9e-26 90.8 17.2 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Ldh_1_C PF02866.18 KXX73209.1 - 2.1e-47 161.2 0.0 2.9e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXX73209.1 - 4.1e-44 150.1 0.1 6e-44 149.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXX73209.1 - 0.0081 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2015 PF09435.10 KXX73210.1 - 1.4e-44 150.5 0.0 1.6e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) PCI PF01399.27 KXX73211.1 - 7e-21 74.7 0.0 2.4e-20 73.0 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KXX73211.1 - 2.7e-16 59.3 0.9 7.1e-16 58.0 0.9 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Phage_Nu1 PF07471.12 KXX73211.1 - 6.5 6.5 7.8 1.1 9.0 1.4 2.6 2 1 2 4 4 4 0 Phage DNA packaging protein Nu1 eIF-5a PF01287.20 KXX73212.1 - 3.1e-06 27.2 0.1 5.6e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold NFACT-C PF11923.8 KXX73213.1 - 3.7e-40 136.1 1.0 3.7e-40 136.1 1.0 3.0 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 KXX73213.1 - 1.8e-37 129.2 5.6 1.8e-37 129.2 5.6 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KXX73213.1 - 1.6e-31 109.1 0.0 3.9e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain Methyltransf_23 PF13489.6 KXX73214.1 - 0.0079 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXX73214.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NACHT PF05729.12 KXX73215.1 - 6.9e-11 42.3 0.3 2.3e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX73215.1 - 1.2e-06 29.0 0.2 1.2e-06 29.0 0.2 1.8 2 0 0 2 2 2 1 AAA ATPase domain SesA PF17107.5 KXX73215.1 - 0.00026 21.2 0.1 0.00072 19.7 0.1 1.8 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXX73215.1 - 0.00053 19.4 0.2 0.00092 18.6 0.2 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KXX73215.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rx_N PF18052.1 KXX73215.1 - 0.021 15.1 0.2 0.055 13.8 0.2 1.7 1 0 0 1 1 1 0 Rx N-terminal domain AAA_18 PF13238.6 KXX73215.1 - 0.034 14.7 0.0 0.085 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KXX73215.1 - 0.038 13.2 0.0 0.094 11.9 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain HTH_30 PF13556.6 KXX73215.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain AAA_22 PF13401.6 KXX73215.1 - 0.064 13.5 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KXX73215.1 - 0.085 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.23 KXX73215.1 - 0.12 12.4 0.1 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Utp13 PF08625.11 KXX73216.1 - 2e-51 173.7 0.3 3.1e-51 173.0 0.3 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KXX73216.1 - 2.9e-44 148.2 18.7 3.8e-07 30.7 0.0 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX73216.1 - 4.1e-14 52.6 2.9 0.12 12.7 0.0 8.8 6 2 3 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KXX73216.1 - 7.7e-05 21.6 5.5 7 5.3 0.0 6.1 4 3 2 7 7 7 3 Nup133 N terminal like Nup160 PF11715.8 KXX73216.1 - 0.00034 19.4 2.7 0.22 10.1 0.1 4.7 4 2 1 5 5 5 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXX73216.1 - 0.0019 17.2 0.0 0.52 9.2 0.0 3.6 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein UCH PF00443.29 KXX73217.1 - 2.8e-21 76.2 0.0 4.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXX73217.1 - 7.4e-12 45.4 0.1 1.6e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXX73217.1 - 0.0073 15.9 0.4 0.079 12.5 0.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CENP-S PF15630.6 KXX73218.1 - 3.4e-33 113.8 0.2 8.2e-33 112.6 0.1 1.6 1 1 1 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 KXX73218.1 - 4.2e-08 33.3 0.2 4.8e-08 33.1 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXX73218.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DUF2972 PF11186.8 KXX73218.1 - 0.052 13.5 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) TFIID-18kDa PF02269.16 KXX73218.1 - 0.062 13.3 0.1 0.078 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit MTHFR PF02219.17 KXX73220.1 - 8.4e-101 337.1 0.0 1.3e-100 336.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase IF4E PF01652.18 KXX73221.1 - 2.4e-55 186.7 0.0 3.9e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Coilin_N PF15862.5 KXX73221.1 - 0.038 13.8 7.1 0.061 13.1 7.1 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF4834 PF16118.5 KXX73221.1 - 5.6 8.0 9.0 12 7.0 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 KXX73222.1 - 0.016 15.2 1.6 0.016 15.2 1.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.12 KXX73222.1 - 0.11 13.0 0.6 0.18 12.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HLH PF00010.26 KXX73223.1 - 2.2e-11 43.6 0.1 2.2e-11 43.6 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3237 PF11578.8 KXX73224.1 - 2.5e-35 121.5 0.0 1.9e-34 118.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 KXX73224.1 - 0.0006 19.8 3.3 0.25 11.4 0.5 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 KXX73224.1 - 0.058 13.7 4.2 2.9 8.3 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 KXX73224.1 - 0.23 11.4 4.0 8.9 6.3 0.4 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_Tnp_IS91 PF14319.6 KXX73224.1 - 5.1 7.2 10.9 11 6.2 3.1 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain MFS_1 PF07690.16 KXX73225.1 - 1.6e-40 139.1 32.9 1.6e-40 139.1 32.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX73225.1 - 3e-07 29.2 2.9 4.4e-07 28.7 2.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3632 PF12311.8 KXX73226.1 - 1.2e-38 133.3 2.6 1.2e-38 133.3 2.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) DUF963 PF06131.11 KXX73226.1 - 0.16 11.4 0.7 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Ribonuclease PF00545.20 KXX73227.1 - 6.7e-11 42.8 0.0 1e-10 42.2 0.0 1.3 1 0 0 1 1 1 1 ribonuclease Glyco_hydro_47 PF01532.20 KXX73228.1 - 3.9e-154 513.9 0.0 4.6e-154 513.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Helicase_C PF00271.31 KXX73229.1 - 9e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXX73229.1 - 0.00023 20.0 0.0 0.0024 16.6 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Glyco_hydro_7 PF00840.20 KXX73231.1 - 1.4e-164 548.0 2.9 1.5e-164 547.8 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Beach PF02138.18 KXX73232.1 - 5.3e-119 396.7 0.0 9.7e-119 395.8 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KXX73232.1 - 1.4e-10 41.2 0.1 1.4e-10 41.2 0.1 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KXX73232.1 - 6.9e-10 39.3 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KXX73232.1 - 0.00012 22.8 0.5 4.4 8.4 0.1 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Prok_Ub PF14454.6 KXX73232.1 - 0.024 14.3 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic Ubiquitin DUF4704 PF15787.5 KXX73232.1 - 0.026 13.8 0.3 0.17 11.1 0.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4704) DUF4800 PF16057.5 KXX73232.1 - 0.029 13.6 2.3 0.054 12.8 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) DCAF17 PF15802.5 KXX73232.1 - 0.21 10.2 0.3 0.33 9.6 0.3 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 17 K_channel_TID PF07941.11 KXX73232.1 - 0.23 11.9 7.1 0.7 10.4 7.1 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DDOST_48kD PF03345.14 KXX73234.1 - 2.4e-166 553.7 0.0 2.8e-166 553.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Peptidase_S8 PF00082.22 KXX73235.1 - 1e-35 123.4 7.9 1.8e-35 122.6 7.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXX73235.1 - 1.5e-22 80.1 0.5 3.1e-22 79.0 0.5 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 PPR_2 PF13041.6 KXX73236.1 - 0.0029 17.7 0.0 1.9 8.7 0.0 3.6 4 0 0 4 4 4 1 PPR repeat family MOZART2 PF12926.7 KXX73236.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated PPR PF01535.20 KXX73236.1 - 0.17 12.2 0.1 32 5.1 0.0 2.9 2 0 0 2 2 2 0 PPR repeat PP2C PF00481.21 KXX73237.1 - 6.6e-84 281.6 0.0 1.1e-83 280.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.12 KXX73238.1 - 1.5e-12 47.4 7.5 0.00028 21.0 0.4 4.6 5 0 0 5 5 5 3 Putative Ig domain DUF4448 PF14610.6 KXX73238.1 - 0.061 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Methyltransf_16 PF10294.9 KXX73239.1 - 2.1e-43 148.0 0.0 2.8e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXX73239.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Chorion_2 PF03964.15 KXX73240.1 - 0.016 16.0 0.2 0.047 14.5 0.2 1.8 1 0 0 1 1 1 0 Chorion family 2 CAP_N PF01213.19 KXX73240.1 - 0.6 9.5 13.1 0.86 9.0 13.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1712 PF08217.11 KXX73241.1 - 1.9e-10 39.9 0.0 1.5e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) HET PF06985.11 KXX73242.1 - 1.8e-20 73.8 0.0 2.8e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HSP70 PF00012.20 KXX73243.1 - 1.2e-08 33.6 0.1 4.2e-08 31.8 0.1 1.9 1 1 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.25 KXX73243.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family MreB_Mbl PF06723.13 KXX73243.1 - 0.089 11.6 0.0 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein Tropomyosin_1 PF12718.7 KXX73245.1 - 0.01 16.0 10.7 0.026 14.7 10.7 1.6 1 0 0 1 1 1 0 Tropomyosin like DUF724 PF05266.14 KXX73245.1 - 0.013 15.4 7.5 0.013 15.4 7.5 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF724) T3SSipB PF16535.5 KXX73245.1 - 0.017 15.6 13.2 0.022 15.3 12.6 1.4 1 1 0 1 1 1 0 Type III cell invasion protein SipB Macoilin PF09726.9 KXX73245.1 - 0.022 13.4 5.3 0.026 13.1 5.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4200 PF13863.6 KXX73245.1 - 0.031 14.7 14.0 0.079 13.4 14.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF745 PF05335.13 KXX73245.1 - 0.07 12.8 11.3 0.12 12.1 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ATG16 PF08614.11 KXX73245.1 - 0.096 12.9 13.9 0.17 12.1 13.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ApoO PF09769.9 KXX73245.1 - 0.14 12.1 2.6 0.23 11.4 1.4 2.0 2 0 0 2 2 2 0 Apolipoprotein O FH2 PF02181.23 KXX73245.1 - 0.21 10.7 5.2 0.36 9.9 5.2 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Vps53_N PF04100.12 KXX73245.1 - 0.47 9.4 8.6 1 8.2 8.6 1.6 1 1 0 1 1 1 0 Vps53-like, N-terminal CorA PF01544.18 KXX73245.1 - 0.48 9.7 3.7 0.75 9.1 3.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Alanine_zipper PF11839.8 KXX73245.1 - 0.55 10.6 9.4 0.2 12.0 3.0 2.6 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein FAM76 PF16046.5 KXX73245.1 - 0.56 9.5 9.2 0.84 8.9 9.2 1.2 1 0 0 1 1 1 0 FAM76 protein Fmp27_WPPW PF10359.9 KXX73245.1 - 0.69 8.7 8.8 1.8 7.3 8.1 1.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.6 KXX73245.1 - 0.78 8.3 11.8 0.087 11.5 3.0 2.1 1 1 1 2 2 2 0 AAA domain Laminin_II PF06009.12 KXX73245.1 - 0.8 9.7 12.7 4.6 7.3 9.9 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF1690 PF07956.11 KXX73245.1 - 0.94 9.9 15.5 3.6 8.0 12.8 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) CCDC-167 PF15188.6 KXX73245.1 - 1.9 8.9 6.2 6 7.3 0.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 KXX73245.1 - 2.4 7.4 16.1 7.3 5.8 16.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 KXX73245.1 - 2.5 5.5 20.5 3.6 5.0 19.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) COG5 PF10392.9 KXX73245.1 - 2.5 8.3 9.6 1.8 8.8 7.5 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 TPR_MLP1_2 PF07926.12 KXX73245.1 - 2.7 8.1 18.5 0.87 9.7 15.7 1.6 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXX73245.1 - 3 6.6 16.2 0.88 8.4 13.3 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KXX73245.1 - 5.1 7.3 15.6 3.6 7.8 12.8 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cnn_1N PF07989.11 KXX73245.1 - 9.4 6.5 12.4 3.1 8.0 4.0 3.0 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 KXX73245.1 - 9.7 6.3 15.4 31 4.6 3.9 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Pec_lyase_C PF00544.19 KXX73246.1 - 2.7e-32 112.1 5.4 3.7e-32 111.6 5.1 1.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXX73246.1 - 0.0002 21.2 14.8 0.00045 20.1 5.2 2.8 1 1 2 3 3 3 2 Right handed beta helix region MctB PF11382.8 KXX73246.1 - 0.054 13.2 0.2 0.71 9.5 0.0 2.0 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB NosD PF05048.13 KXX73246.1 - 0.072 12.3 6.5 0.38 10.0 2.1 2.2 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) DHR10 PF18595.1 KXX73248.1 - 0.14 12.3 21.5 0.16 12.1 10.4 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain CDC27 PF09507.10 KXX73248.1 - 8.3 5.7 12.4 5.5 6.3 4.1 2.6 3 0 0 3 3 3 0 DNA polymerase subunit Cdc27 MFS_1 PF07690.16 KXX73249.1 - 4.8e-21 75.1 29.6 4.8e-21 75.1 29.6 2.7 1 1 1 3 3 3 3 Major Facilitator Superfamily NUDIX PF00293.28 KXX73250.1 - 9.3e-18 64.5 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KXX73251.1 - 4e-05 23.7 0.1 5.9e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_1 PF00561.20 KXX73253.1 - 2.5e-47 161.7 0.0 7.4e-47 160.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXX73253.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase GMC_oxred_N PF00732.19 KXX73255.1 - 8.6e-67 225.6 0.0 1.1e-66 225.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX73255.1 - 2.9e-34 118.7 0.0 5.2e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX73255.1 - 3.7e-08 32.9 0.4 0.0023 17.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXX73255.1 - 1.3e-05 25.0 3.0 0.00031 20.5 2.5 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX73255.1 - 6.2e-05 23.2 0.2 0.00014 22.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX73255.1 - 0.00012 21.5 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase XPC-binding PF09280.11 KXX73255.1 - 0.00092 18.9 0.2 0.0025 17.5 0.1 1.8 2 0 0 2 2 2 1 XPC-binding domain Pyr_redox_2 PF07992.14 KXX73255.1 - 0.0011 18.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX73255.1 - 0.0016 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXX73255.1 - 0.003 16.8 0.1 0.0059 15.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXX73255.1 - 0.025 13.3 0.1 0.052 12.2 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein ADH_N_2 PF16884.5 KXX73255.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase NAD_binding_9 PF13454.6 KXX73255.1 - 0.19 11.7 1.0 0.47 10.4 0.1 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXX73255.1 - 0.22 10.6 0.0 3.3 6.7 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_2 PF02230.16 KXX73257.1 - 0.00039 20.3 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KXX73257.1 - 0.00084 19.1 0.2 0.0061 16.2 0.2 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXX73257.1 - 0.084 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sugar_tr PF00083.24 KXX73258.1 - 7.5e-32 110.8 5.4 8.5e-32 110.6 5.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KXX73259.1 - 1.7e-51 175.5 10.5 1.7e-51 175.5 10.5 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX73259.1 - 1.5e-08 33.9 28.3 4.4e-08 32.4 28.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Erg28 PF03694.13 KXX73261.1 - 8.5e-15 55.1 0.2 9.7e-15 54.9 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein NCBP3 PF10309.9 KXX73261.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Nuclear cap-binding protein subunit 3 adh_short PF00106.25 KXX73262.1 - 2.8e-20 72.6 0.0 1.3e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73262.1 - 9.1e-16 58.1 0.2 1.5e-13 50.8 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73262.1 - 2.5e-05 24.2 0.1 4.5e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KXX73263.1 - 3.6e-39 134.8 0.0 4.7e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2448 PF10476.9 KXX73265.1 - 0.63 9.9 4.0 12 5.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function C-terminus (DUF2448) Metallophos PF00149.28 KXX73266.1 - 7.9e-11 42.8 1.1 1.3e-10 42.2 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX73266.1 - 4e-07 30.4 0.0 2.2e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EMP70 PF02990.16 KXX73267.1 - 1.7e-203 677.0 0.0 2e-203 676.8 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Peptidase_S9 PF00326.21 KXX73269.1 - 1.5e-53 181.4 0.0 5.4e-53 179.6 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXX73269.1 - 0.14 10.8 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) NuA4 PF09340.10 KXX73270.1 - 1.8e-23 82.2 0.0 3.4e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 E1-E2_ATPase PF00122.20 KXX73271.1 - 1e-45 155.5 0.1 3e-45 153.9 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXX73271.1 - 1.1e-43 149.1 0.2 1.1e-43 149.1 0.2 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KXX73271.1 - 1.1e-19 69.8 0.0 2.2e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KXX73271.1 - 4.9e-18 66.2 8.0 3.1e-17 63.6 5.9 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXX73271.1 - 3.3e-12 46.3 0.0 6.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXX73271.1 - 1.4e-05 25.0 1.9 2.6e-05 24.1 1.9 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 KXX73272.1 - 9.6e-34 115.9 0.0 2e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXX73272.1 - 2e-08 33.4 0.1 4.9e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Spt20 PF12090.8 KXX73272.1 - 0.34 10.5 5.2 1.1 8.8 0.8 2.3 2 0 0 2 2 2 0 Spt20 family SPAN PF02510.14 KXX73272.1 - 2.1 7.5 6.3 3.9 6.6 6.3 1.3 1 0 0 1 1 1 0 Surface presentation of antigens protein Methyltransf_23 PF13489.6 KXX73273.1 - 0.00027 20.8 0.0 0.00051 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GMC_oxred_N PF00732.19 KXX73275.1 - 8.8e-45 153.3 0.0 2.1e-44 152.1 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX73275.1 - 3.8e-22 79.4 0.0 6.2e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXX73275.1 - 0.03 13.6 0.4 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX73275.1 - 0.047 12.8 0.6 3 6.8 0.6 2.2 2 0 0 2 2 2 0 FAD binding domain Autoind_bind PF03472.15 KXX73275.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain GMC_oxred_N PF00732.19 KXX73276.1 - 8.8e-45 153.3 0.0 2.1e-44 152.1 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX73276.1 - 3.8e-22 79.4 0.0 6.2e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXX73276.1 - 0.03 13.6 0.4 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX73276.1 - 0.047 12.8 0.6 3 6.8 0.6 2.2 2 0 0 2 2 2 0 FAD binding domain Autoind_bind PF03472.15 KXX73276.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain HET PF06985.11 KXX73279.1 - 3e-23 82.8 0.4 3.9e-22 79.2 0.0 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Apt1 PF10351.9 KXX73281.1 - 3.2 6.5 5.7 4.9 5.9 5.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nup88 PF10168.9 KXX73282.1 - 0.018 12.9 3.9 1.4 6.7 1.1 2.8 2 2 0 2 2 2 0 Nuclear pore component Snapin_Pallidin PF14712.6 KXX73282.1 - 0.24 11.9 1.9 5.5 7.5 0.3 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Rootletin PF15035.6 KXX73282.1 - 0.52 10.3 5.5 0.35 10.9 3.4 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Cytochrom_C_2 PF01322.20 KXX73282.1 - 0.65 10.9 1.9 1.7 9.5 1.0 2.1 1 1 0 1 1 1 0 Cytochrome C' TPR_MLP1_2 PF07926.12 KXX73282.1 - 1.3 9.0 9.7 0.93 9.6 2.9 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Csm1_N PF18504.1 KXX73282.1 - 4 7.9 4.9 3.4 8.1 1.5 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Sedlin_N PF04628.13 KXX73283.1 - 2.6e-47 160.2 0.0 3e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXX73283.1 - 2.4e-05 24.3 0.0 0.00052 20.0 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family CENP-T_C PF15511.6 KXX73284.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXX73284.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KXX73284.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXX73284.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXX73284.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXX73284.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXX73284.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KXX73284.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KXX73284.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region RRM_1 PF00076.22 KXX73285.1 - 4.6e-16 58.4 0.0 6.5e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.9 KXX73286.1 - 1.1e-45 154.2 0.9 1.3e-45 154.0 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 MPS2 PF17060.5 KXX73286.1 - 0.0057 16.0 0.1 0.0059 15.9 0.1 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 DUF3605 PF12239.8 KXX73287.1 - 8.1e-58 195.1 0.0 9.7e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) TPR_2 PF07719.17 KXX73288.1 - 2.1e-35 118.0 30.2 7.9e-06 25.6 0.1 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXX73288.1 - 3.9e-34 115.1 19.6 1.2e-07 31.2 0.1 9.5 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX73288.1 - 3.9e-33 113.5 21.1 8.8e-26 90.0 0.1 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXX73288.1 - 2.4e-23 82.2 24.5 5.1e-05 23.5 0.2 8.4 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXX73288.1 - 6.3e-23 81.1 17.4 4e-08 33.7 3.3 7.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXX73288.1 - 1.2e-22 78.2 12.5 0.015 15.4 0.4 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXX73288.1 - 5.5e-21 73.5 23.1 0.012 16.4 0.1 10.3 4 1 7 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXX73288.1 - 5.7e-20 71.7 27.6 1e-06 29.3 0.7 8.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KXX73288.1 - 6.8e-17 60.9 12.4 6.7e-07 28.9 3.2 7.8 5 1 3 8 8 7 4 TPR repeat TPR_17 PF13431.6 KXX73288.1 - 4.1e-16 58.1 13.1 0.011 16.1 0.4 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXX73288.1 - 9e-16 56.7 12.6 0.0017 18.2 0.1 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXX73288.1 - 5.2e-11 42.4 15.6 0.3 11.8 0.5 9.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXX73288.1 - 9.8e-08 32.0 10.3 0.69 10.1 0.0 5.4 3 1 2 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 KXX73288.1 - 7.5e-06 25.4 10.4 0.09 12.0 2.1 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.9 KXX73288.1 - 0.0034 17.2 2.2 11 5.6 2.8 3.3 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) NARP1 PF12569.8 KXX73288.1 - 0.04 12.8 3.8 2.2 7.1 0.0 2.9 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KXX73288.1 - 0.068 13.1 12.6 12 6.0 0.0 6.6 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXX73288.1 - 0.12 12.8 5.5 1.2 9.6 1.4 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXX73288.1 - 0.28 11.9 7.4 3.8 8.4 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXX73288.1 - 5.5 7.1 8.7 26 5.0 0.1 4.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TMEM208_SND2 PF05620.11 KXX73289.1 - 7.1e-53 178.8 0.2 7.8e-53 178.7 0.2 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 LcnG-beta PF11632.8 KXX73289.1 - 0.15 12.0 3.1 0.3 11.1 3.1 1.5 1 0 0 1 1 1 0 Lactococcin G-beta TRAPPC10 PF12584.8 KXX73290.1 - 3.9e-27 94.9 0.0 9e-27 93.7 0.0 1.6 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 M20_dimer PF07687.14 KXX73291.1 - 3.5e-20 71.9 0.3 7.9e-20 70.8 0.1 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXX73291.1 - 1.6e-16 60.6 0.1 1.2e-15 57.8 0.1 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 IF-2B PF01008.17 KXX73292.1 - 4e-74 249.3 0.2 4.7e-74 249.1 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family adh_short PF00106.25 KXX73293.1 - 3.8e-19 68.9 0.1 1.5e-15 57.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73293.1 - 7.8e-09 35.4 0.7 3e-07 30.2 0.3 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73293.1 - 7.3e-05 22.8 0.4 0.00014 21.8 0.1 1.6 2 0 0 2 2 2 1 KR domain DUF1491 PF07372.12 KXX73293.1 - 0.075 13.4 0.0 27 5.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1491) Prenyltrans PF00432.21 KXX73294.1 - 1.6e-35 120.5 17.4 4.7e-11 42.2 0.2 6.9 8 0 0 8 8 8 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KXX73294.1 - 0.016 14.3 0.0 26 3.8 0.0 3.7 4 0 0 4 4 4 0 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 KXX73294.1 - 0.13 11.3 0.0 15 4.5 0.0 2.7 2 1 0 2 2 2 0 A-macroglobulin TED domain FAD_binding_4 PF01565.23 KXX73295.1 - 9.4e-27 93.4 0.7 1.7e-26 92.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX73295.1 - 0.0087 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cupin_2 PF07883.11 KXX73296.1 - 7e-08 32.1 0.1 1.2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Cupin domain ANAPC10 PF03256.16 KXX73297.1 - 4e-47 160.3 0.0 5.8e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 KXX73297.1 - 0.018 15.3 0.0 0.077 13.2 0.0 1.9 1 1 1 2 2 2 0 PITH domain UBX PF00789.20 KXX73297.1 - 0.11 12.7 0.0 22 5.3 0.0 2.9 3 0 0 3 3 3 0 UBX domain CTP_transf_like PF01467.26 KXX73298.1 - 0.0038 17.4 0.0 0.0074 16.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Peptidase_S28 PF05577.12 KXX73299.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Serine carboxypeptidase S28 2OG-FeII_Oxy_3 PF13640.6 KXX73300.1 - 1e-09 39.1 0.0 1.6e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KXX73301.1 - 0.00056 19.0 0.0 0.00077 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thioredoxin_6 PF13848.6 KXX73302.1 - 1.7e-21 76.9 0.0 7.7e-19 68.3 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KXX73302.1 - 3.6e-06 26.9 0.0 2.5e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin T2SSE_N PF05157.15 KXX73302.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Mre11_DNA_bind PF04152.14 KXX73303.1 - 6.5e-53 179.5 0.2 1.4e-52 178.4 0.2 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KXX73303.1 - 9.6e-16 58.9 1.0 2.5e-15 57.5 0.6 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX73303.1 - 0.00052 20.2 0.0 0.011 15.9 0.0 2.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain TIP120 PF08623.10 KXX73303.1 - 0.078 12.7 0.3 0.39 10.5 0.1 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) PBP1_TM PF14812.6 KXX73303.1 - 0.42 11.0 14.1 0.045 14.1 3.2 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORC6 PF05460.13 KXX73303.1 - 1.8 7.7 10.0 4.1 6.6 10.0 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TFIID_30kDa PF03540.13 KXX73304.1 - 2.9e-25 88.0 0.3 4.3e-25 87.4 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KXX73304.1 - 0.11 13.1 0.4 0.23 12.1 0.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Sugar_tr PF00083.24 KXX73305.1 - 4.1e-37 128.1 25.1 3.3e-30 105.3 10.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXX73305.1 - 3.6e-08 32.7 23.6 3.6e-08 32.7 23.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 KXX73306.1 - 0.43 9.8 2.3 0.44 9.8 0.1 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF3177 PF11375.8 KXX73306.1 - 3.3 7.4 11.5 0.34 10.7 6.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3177) Glyco_hydro_115 PF15979.5 KXX73307.1 - 9.6e-131 436.2 2.7 1.3e-130 435.8 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXX73307.1 - 3.1e-52 176.9 0.1 7.2e-52 175.7 0.1 1.7 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 KXX73307.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus adh_short PF00106.25 KXX73308.1 - 3.3e-12 46.3 0.0 8.1e-12 45.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX73308.1 - 0.00021 21.3 0.1 0.00035 20.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXX73308.1 - 0.0003 20.4 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3842 PF12953.7 KXX73308.1 - 0.015 15.7 0.1 0.027 14.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Semialdhyde_dh PF01118.24 KXX73308.1 - 0.024 15.1 0.0 0.053 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peripla_BP_6 PF13458.6 KXX73308.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein EII-Sor PF03609.14 KXX73309.1 - 0.53 9.6 3.1 0.56 9.6 1.8 1.6 1 1 0 1 1 1 0 PTS system sorbose-specific iic component Abhydrolase_6 PF12697.7 KXX73310.1 - 6.6e-12 46.5 0.2 9.8e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXX73310.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 KXX73310.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Aldedh PF00171.22 KXX73311.1 - 6.2e-146 486.5 0.0 7.1e-146 486.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PI-PLC-X PF00388.19 KXX73312.1 - 2.1e-47 160.4 0.0 3e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXX73312.1 - 2.6e-36 124.4 0.0 4.2e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF4701 PF15773.5 KXX73312.1 - 0.033 13.2 3.9 0.051 12.6 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) Med19 PF10278.9 KXX73312.1 - 0.05 13.5 0.3 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 IMUP PF15761.5 KXX73312.1 - 0.059 14.1 2.0 0.18 12.5 2.0 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Homeobox_KN PF05920.11 KXX73315.1 - 1e-19 70.1 0.2 1.9e-19 69.3 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXX73315.1 - 2e-08 34.0 0.8 6.6e-08 32.3 0.8 1.9 1 0 0 1 1 1 1 Homeodomain SKG6 PF08693.10 KXX73316.1 - 2.7e-06 26.7 3.3 2.7e-06 26.7 3.3 2.4 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 KXX73316.1 - 0.011 16.3 7.4 0.018 15.6 7.4 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J TMEM154 PF15102.6 KXX73316.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Rax2 PF12768.7 KXX73316.1 - 0.074 12.5 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity MGC-24 PF05283.11 KXX73316.1 - 0.91 10.0 5.5 1.4 9.4 5.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glycoprotein PF03409.15 KXX73316.1 - 3.3 6.4 8.4 4.6 6.0 8.4 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein Phospholip_A2_3 PF09056.11 KXX73317.1 - 2.4e-44 150.5 0.1 3.2e-44 150.1 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Fringe PF02434.16 KXX73318.1 - 2.7e-07 30.3 0.0 4.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KXX73318.1 - 0.006 16.5 1.5 0.013 15.4 1.5 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXX73318.1 - 0.022 14.7 0.7 0.045 13.7 0.7 1.4 1 0 0 1 1 1 0 PAN domain HAUS5 PF14817.6 KXX73318.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Cu-oxidase_2 PF07731.14 KXX73319.1 - 2e-28 98.8 3.2 1.3e-25 89.7 1.9 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXX73319.1 - 7.7e-20 71.1 0.8 2.7e-19 69.3 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXX73319.1 - 0.00016 21.8 0.0 0.018 15.2 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase TPR_1 PF00515.28 KXX73320.1 - 1.3e-07 31.2 9.1 5.6e-05 22.8 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX73320.1 - 1.6e-05 24.6 0.5 0.96 9.6 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXX73320.1 - 1.7e-05 24.5 17.0 0.00079 19.4 0.0 7.5 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX73320.1 - 9.4e-05 22.6 5.3 0.11 12.8 0.5 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXX73320.1 - 0.00014 21.8 2.9 0.12 12.7 0.0 5.7 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX73320.1 - 0.00018 22.1 14.4 3.3 8.8 0.0 7.6 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX73320.1 - 0.001 19.5 4.0 4.1 8.0 0.1 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXX73320.1 - 0.0019 17.8 5.2 0.9 9.3 0.0 5.5 6 0 0 6 6 6 1 TPR repeat TetR_C_15 PF17918.1 KXX73320.1 - 0.025 15.3 0.8 0.1 13.4 0.8 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TPR_6 PF13174.6 KXX73320.1 - 0.047 14.3 5.2 17 6.3 0.0 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXX73320.1 - 0.058 14.1 21.0 0.34 11.6 0.0 7.4 8 1 1 9 9 8 0 Tetratricopeptide repeat RTA1 PF04479.13 KXX73321.1 - 2.9e-16 59.7 1.0 2.3e-10 40.4 0.1 2.1 2 0 0 2 2 2 2 RTA1 like protein DUF5527 PF17665.1 KXX73321.1 - 0.014 14.9 2.1 0.024 14.2 2.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Glyco_hydro_3_C PF01915.22 KXX73322.1 - 5.7e-44 150.5 0.0 1.5e-43 149.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX73322.1 - 1.4e-41 142.9 0.0 2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX73322.1 - 1.4e-20 73.1 0.2 2.6e-20 72.3 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_M48_N PF16491.5 KXX73323.1 - 1.3e-65 220.7 9.0 1.3e-65 220.7 9.0 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KXX73323.1 - 1.3e-45 155.6 0.0 2.5e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KXX73323.1 - 0.003 16.8 0.7 0.006 15.8 0.7 1.5 1 1 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.6 KXX73323.1 - 0.082 12.7 0.8 0.24 11.2 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) SprT-like PF10263.9 KXX73323.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 SprT-like family PGA2 PF07543.12 KXX73324.1 - 1.1e-38 132.3 2.7 1.3e-38 132.1 2.7 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 WD40 PF00400.32 KXX73324.1 - 4.9e-05 24.0 0.7 0.17 12.8 0.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 KXX73324.1 - 0.006 15.3 0.1 0.0075 15.0 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SLY PF12485.8 KXX73324.1 - 0.062 14.0 3.1 0.1 13.4 3.1 1.3 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein PPTA PF01239.22 KXX73325.1 - 1.8e-37 126.0 15.7 2.6e-07 30.1 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.6 KXX73325.1 - 0.21 11.9 3.4 0.66 10.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX73325.1 - 0.42 11.3 2.2 2.3 9.0 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidase PF01425.21 KXX73325.1 - 2.7 6.9 9.3 0.93 8.4 6.2 1.6 2 0 0 2 2 2 0 Amidase TPR_7 PF13176.6 KXX73325.1 - 4.3 7.6 5.3 3 8.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 KXX73326.1 - 3.1e-15 56.2 0.0 6.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXX73326.1 - 2e-09 37.7 0.0 4.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KXX73326.1 - 0.0022 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature HTH_6 PF01418.17 KXX73326.1 - 0.015 15.3 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family ABM PF03992.16 KXX73327.1 - 4.9e-06 26.6 2.6 0.0023 18.0 0.1 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Ribosomal_L34 PF00468.17 KXX73328.1 - 2.3e-12 46.7 12.1 4.2e-12 45.8 12.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Ribosomal_L38e PF01781.18 KXX73329.1 - 3.9e-34 116.6 5.5 4.7e-34 116.3 5.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family ZapB PF06005.12 KXX73331.1 - 0.00018 21.9 5.1 0.00018 21.9 5.1 1.7 1 1 0 1 1 1 1 Cell division protein ZapB HALZ PF02183.18 KXX73331.1 - 0.0015 18.8 7.4 0.032 14.5 1.2 2.7 2 1 1 3 3 3 2 Homeobox associated leucine zipper Rootletin PF15035.6 KXX73331.1 - 0.0034 17.4 3.1 0.0034 17.4 3.1 1.2 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 KXX73331.1 - 0.0041 16.9 1.4 0.0041 16.9 1.4 1.8 2 0 0 2 2 2 1 Septum formation initiator Cep57_CLD_2 PF14197.6 KXX73331.1 - 0.0073 16.4 1.7 0.0073 16.4 1.7 1.7 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 JIP_LZII PF16471.5 KXX73331.1 - 0.009 16.2 4.8 0.032 14.4 1.0 2.0 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II KASH_CCD PF14662.6 KXX73331.1 - 0.022 14.6 2.4 0.022 14.6 2.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH APC_N_CC PF16689.5 KXX73331.1 - 0.037 14.1 2.8 1.7 8.8 1.0 2.5 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain bZIP_2 PF07716.15 KXX73331.1 - 0.047 13.8 1.4 0.047 13.8 1.4 2.8 2 1 1 3 3 3 0 Basic region leucine zipper Mto2_bdg PF12808.7 KXX73331.1 - 0.062 13.6 1.4 0.062 13.6 1.4 1.9 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GIT_CC PF16559.5 KXX73331.1 - 0.075 12.9 3.6 0.092 12.6 3.6 1.3 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 KXX73331.1 - 0.1 12.7 0.9 0.1 12.7 0.9 2.2 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 KXX73331.1 - 0.13 12.6 3.4 0.33 11.3 3.4 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family Cnn_1N PF07989.11 KXX73331.1 - 0.15 12.2 3.9 0.32 11.2 3.9 1.6 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF5082 PF16888.5 KXX73331.1 - 0.19 12.0 4.2 0.37 11.1 1.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) YabA PF06156.13 KXX73331.1 - 0.22 12.2 2.9 0.44 11.2 2.9 1.6 1 1 0 1 1 1 0 Initiation control protein YabA PikAIV_N PF18605.1 KXX73331.1 - 0.86 9.2 7.6 2.5 7.8 1.2 2.5 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain p450 PF00067.22 KXX73332.1 - 1.9e-24 86.3 0.0 2.5e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KXX73333.1 - 2.5e-39 135.2 59.5 2.5e-39 135.2 59.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX73333.1 - 4e-12 45.4 16.7 4e-12 45.4 16.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX73333.1 - 8.5e-09 34.8 13.3 8.5e-09 34.8 13.3 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3675 PF12428.8 KXX73333.1 - 0.18 12.4 0.2 0.36 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) p450 PF00067.22 KXX73334.1 - 1.7e-34 119.4 0.0 2.7e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_8 PF13450.6 KXX73335.1 - 2.2e-11 43.8 1.8 2.4e-11 43.7 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXX73335.1 - 1.5e-09 37.7 0.4 3.3e-09 36.6 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXX73335.1 - 2.5e-09 37.0 0.0 5.3e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXX73335.1 - 1.1e-05 25.2 0.6 3.1e-05 23.7 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX73335.1 - 1.8e-05 24.2 0.1 3.2e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX73335.1 - 2.8e-05 23.5 0.0 4.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX73335.1 - 3.9e-05 22.5 0.1 5.8e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXX73335.1 - 5.7e-05 22.4 0.6 5.7e-05 22.4 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KXX73335.1 - 0.00031 21.3 0.1 0.00073 20.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX73335.1 - 0.0011 18.2 0.2 0.0011 18.2 0.2 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXX73335.1 - 0.018 14.3 0.3 0.03 13.6 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KXX73335.1 - 0.053 12.6 0.2 0.083 12.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_4 PF01565.23 KXX73337.1 - 5.7e-21 74.7 0.3 1.3e-20 73.6 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX73337.1 - 0.039 14.1 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Berberine and berberine like GTP_EFTU PF00009.27 KXX73338.1 - 0.02 14.4 0.0 5 6.6 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ank_2 PF12796.7 KXX73339.1 - 6.1e-65 215.8 0.0 1.4e-15 57.6 0.0 6.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX73339.1 - 1.3e-35 121.0 5.0 2.5e-07 30.9 0.0 8.3 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73339.1 - 4.4e-33 109.6 0.0 0.00044 20.5 0.0 10.2 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 KXX73339.1 - 7.2e-33 112.5 0.3 1.8e-06 28.4 0.1 7.0 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXX73339.1 - 8.8e-28 95.5 0.6 0.0021 18.4 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat DUF3716 PF12511.8 KXX73340.1 - 2.1e-11 43.7 1.4 3.3e-11 43.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) MGC-24 PF05283.11 KXX73340.1 - 1.5 9.3 7.3 0.38 11.2 0.6 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SNARE PF05739.19 KXX73341.1 - 0.0002 21.3 0.4 0.0002 21.3 0.4 2.0 2 0 0 2 2 2 1 SNARE domain Lyase_8_N PF08124.11 KXX73341.1 - 0.06 12.3 0.4 0.11 11.4 0.1 1.6 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain CorA PF01544.18 KXX73341.1 - 0.095 12.0 0.2 0.095 12.0 0.2 2.4 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Flp1_like PF16982.5 KXX73341.1 - 0.17 11.3 3.8 0.27 10.7 3.8 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Fungal_trans PF04082.18 KXX73342.1 - 6.6e-11 41.7 0.1 9.1e-11 41.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX73342.1 - 0.0016 18.6 9.9 0.0026 17.8 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1b PF00579.25 KXX73343.1 - 8e-80 268.3 0.0 1.1e-79 267.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KXX73343.1 - 1.5e-47 160.3 0.0 5.1e-47 158.6 0.0 2.0 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain NPR2 PF06218.11 KXX73344.1 - 9.9e-118 393.7 0.0 1.2e-117 393.4 0.0 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Ribosomal_60s PF00428.19 KXX73344.1 - 0.32 11.6 1.5 0.74 10.4 1.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-RING_2 PF13639.6 KXX73345.1 - 4.2e-11 43.0 6.1 7.5e-11 42.2 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXX73345.1 - 5.6e-08 32.4 3.4 1.1e-07 31.5 3.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXX73345.1 - 7.2e-08 32.2 4.9 1.2e-07 31.4 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX73345.1 - 2.4e-06 27.4 3.6 4e-06 26.7 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXX73345.1 - 2.5e-06 27.7 3.7 3.7e-06 27.1 2.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXX73345.1 - 6.7e-06 25.9 6.1 1.1e-05 25.1 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX73345.1 - 3e-05 23.9 5.3 8e-05 22.6 5.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXX73345.1 - 0.00013 21.9 1.1 0.0003 20.8 0.7 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXX73345.1 - 0.0036 17.1 3.0 0.0062 16.4 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXX73345.1 - 0.0064 16.3 5.0 0.014 15.2 5.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXX73345.1 - 0.065 12.9 1.1 0.12 12.0 1.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KXX73345.1 - 0.091 12.7 2.0 0.16 11.9 2.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KXX73345.1 - 0.16 11.8 3.2 0.26 11.1 3.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YdjO PF14169.6 KXX73345.1 - 0.2 11.4 1.4 3.7 7.3 0.1 2.7 2 1 1 3 3 3 0 Cold-inducible protein YdjO zf-RING-like PF08746.11 KXX73345.1 - 0.23 11.8 0.2 0.57 10.5 0.2 1.6 1 0 0 1 1 1 0 RING-like domain DUF4083 PF13314.6 KXX73345.1 - 0.25 11.3 0.2 0.58 10.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) zf-C3HC4_4 PF15227.6 KXX73345.1 - 0.71 10.1 6.9 1.3 9.2 6.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KXX73345.1 - 0.76 9.9 2.7 1.4 9.1 2.7 1.5 1 0 0 1 1 1 0 RING-variant domain LapA_dom PF06305.11 KXX73345.1 - 1 9.3 3.9 0.21 11.4 0.4 1.6 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain Ada3 PF10198.9 KXX73346.1 - 5.2e-59 198.1 0.5 4.1e-57 192.0 0.0 2.7 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Phage_Gp23 PF10669.9 KXX73346.1 - 0.17 12.3 3.6 0.35 11.2 3.6 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF1682 PF07946.14 KXX73346.1 - 0.87 8.7 3.7 1.9 7.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3419 PF11899.8 KXX73347.1 - 1e-162 541.8 0.0 1.2e-162 541.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KXX73347.1 - 2e-14 53.7 0.0 3.8e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX73347.1 - 2.1e-09 38.0 0.0 1.1e-08 35.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX73347.1 - 2.3e-09 37.8 0.0 1.5e-06 28.9 0.0 3.5 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX73347.1 - 6.3e-09 35.5 0.0 0.00031 20.1 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXX73347.1 - 1.1e-07 32.4 0.0 6.2e-05 23.6 0.0 3.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX73347.1 - 4.8e-07 29.7 0.0 1.5e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXX73347.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CybS PF05328.12 KXX73348.1 - 7.5e-47 158.4 0.0 9.3e-47 158.1 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 KXX73348.1 - 0.065 13.3 0.5 0.54 10.3 0.1 2.0 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4238 PF14022.6 KXX73350.1 - 2.8e-66 223.8 0.3 3.8e-66 223.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Pec_lyase_C PF00544.19 KXX73351.1 - 6.5e-41 140.2 3.9 8.3e-41 139.9 3.9 1.1 1 0 0 1 1 1 1 Pectate lyase APH PF01636.23 KXX73352.1 - 1.2e-14 54.9 0.1 7.2e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXX73352.1 - 1.2e-08 34.8 0.1 2.2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KXX73352.1 - 0.00096 18.4 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase p450 PF00067.22 KXX73353.1 - 2.5e-63 214.5 0.0 3.1e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cytochrom_B561 PF03188.16 KXX73354.1 - 0.00021 21.5 7.8 0.00021 21.5 7.8 2.0 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4405 PF14358.6 KXX73354.1 - 0.087 13.4 7.8 1.7 9.3 1.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 KXX73354.1 - 0.23 11.0 12.2 0.023 14.3 4.1 2.3 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF2569 PF10754.9 KXX73354.1 - 0.32 11.4 6.5 2.6 8.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4079 PF13301.6 KXX73354.1 - 1.7 8.8 13.7 2.6 8.2 10.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Glyco_hydro_72 PF03198.14 KXX73355.1 - 7.5e-120 399.9 2.9 1e-119 399.5 2.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXX73355.1 - 2.8e-06 27.0 1.0 1.5e-05 24.5 1.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.25 KXX73357.1 - 8.6e-20 71.0 0.0 5.8e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73357.1 - 7e-16 58.5 0.0 2.6e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73357.1 - 1.7e-08 34.6 0.1 3.1e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX73357.1 - 0.0064 16.0 0.0 0.092 12.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KXX73357.1 - 0.072 12.3 0.2 0.17 11.0 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXX73357.1 - 0.096 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXX73357.1 - 0.14 12.8 0.6 0.24 12.0 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SMP PF04927.12 KXX73358.1 - 1.6e-10 41.3 12.8 5e-07 30.1 3.1 2.2 1 1 1 2 2 2 2 Seed maturation protein adh_short PF00106.25 KXX73359.1 - 3.8e-34 117.9 0.0 2.2e-33 115.4 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73359.1 - 2.5e-26 92.7 0.0 2.6e-25 89.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXX73359.1 - 8.6e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KXX73359.1 - 0.00038 20.4 0.0 0.0094 15.9 0.0 2.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXX73359.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 KXX73359.1 - 0.086 12.3 0.0 0.59 9.5 0.0 2.3 3 1 0 3 3 3 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX73359.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding ABC_tran PF00005.27 KXX73361.1 - 4.7e-06 27.2 0.0 6.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.6 KXX73361.1 - 5.6e-05 23.7 0.2 0.00019 22.0 0.1 1.9 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane PF01061.24 KXX73362.1 - 7.3e-38 130.1 48.8 1.4e-19 70.4 11.3 4.0 4 1 1 5 5 5 3 ABC-2 type transporter PDR_CDR PF06422.12 KXX73362.1 - 2.8e-30 104.1 13.0 1.1e-28 98.9 0.0 4.3 4 0 0 4 4 4 2 CDR ABC transporter ABC_tran PF00005.27 KXX73362.1 - 5.1e-09 36.8 0.0 0.00019 22.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXX73362.1 - 0.0055 16.2 0.0 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KXX73362.1 - 0.54 9.3 22.4 0.6 9.2 9.5 3.2 2 2 1 3 3 3 0 ABC-2 family transporter protein DUF4079 PF13301.6 KXX73362.1 - 3.7 7.7 12.6 0.04 14.1 3.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) DUF2070 PF09843.9 KXX73362.1 - 3.8 5.7 8.5 7.7 4.7 8.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SurE PF01975.17 KXX73363.1 - 1.4e-47 162.0 0.0 1.8e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_4 PF13439.6 KXX73363.1 - 0.073 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Methyltransf_16 PF10294.9 KXX73364.1 - 4.5e-08 33.0 0.0 1.3e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXX73364.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXX73364.1 - 0.17 12.6 0.0 7.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF3479 PF11965.8 KXX73364.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) SUIM_assoc PF16619.5 KXX73365.1 - 3.4 7.8 8.2 8 6.6 8.2 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SNF2_N PF00176.23 KXX73366.1 - 1.3e-68 231.3 1.4 1.4e-63 214.8 0.5 3.1 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX73366.1 - 2.8e-15 56.6 0.0 1.5e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX73366.1 - 3.8e-05 23.8 0.1 0.00012 22.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 KXX73366.1 - 2.4 7.7 5.1 1.3 8.6 0.0 2.5 2 1 0 2 2 2 0 DEAD_2 zf-primase PF09329.11 KXX73367.1 - 1.5e-17 63.1 3.1 2.5e-17 62.4 3.1 1.3 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 KXX73367.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.10 KXX73368.1 - 2.7e-44 151.2 0.0 7e-44 149.8 0.0 1.7 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KXX73368.1 - 7.9e-23 80.5 0.1 2e-22 79.3 0.1 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain TMA7 PF09072.10 KXX73368.1 - 0.063 14.1 6.2 0.17 12.7 6.2 1.8 1 0 0 1 1 1 0 Translation machinery associated TMA7 DUF501 PF04417.12 KXX73368.1 - 1.1 9.1 3.5 9.6 6.0 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DASH_Duo1 PF08651.10 KXX73369.1 - 4.4e-33 112.9 0.4 6.3e-33 112.4 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.14 KXX73369.1 - 0.0093 15.2 5.1 0.011 15.0 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Rrn6 PF10214.9 KXX73369.1 - 0.095 11.2 5.0 0.092 11.2 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BLM_N PF16202.5 KXX73369.1 - 0.11 11.6 2.9 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 N-terminal region of Bloom syndrome protein XRN_M PF17846.1 KXX73369.1 - 0.18 10.7 0.5 0.21 10.5 0.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DASH_Dad2 PF08654.10 KXX73369.1 - 0.36 11.3 4.7 0.9 10.0 4.7 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad2 FCP1_C PF09309.10 KXX73369.1 - 0.4 10.5 10.4 0.63 9.9 10.4 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Atrophin-1 PF03154.15 KXX73369.1 - 6 5.0 10.9 7.8 4.6 10.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family Glyco_hydro_64 PF16483.5 KXX73371.1 - 7.4e-114 380.8 0.0 8.5e-114 380.7 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase EcKinase PF02958.20 KXX73372.1 - 3.4e-16 59.4 0.0 2.5e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KXX73372.1 - 3.3e-10 40.3 0.1 1.8e-09 37.9 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXX73372.1 - 4.7e-06 25.7 0.0 1.7e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1679) RNA_pol_Rpb1_2 PF00623.20 KXX73373.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 DUF983 PF06170.12 KXX73375.1 - 5.9 7.4 10.4 0.44 11.0 2.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) DUF1996 PF09362.10 KXX73376.1 - 1.8e-78 263.8 0.1 2.2e-78 263.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CFEM PF05730.11 KXX73377.1 - 9.9e-12 44.8 7.3 1.3e-11 44.4 7.3 1.2 1 0 0 1 1 1 1 CFEM domain PRP3 PF08572.10 KXX73378.1 - 5.2e-74 248.7 8.5 8.7e-74 248.0 8.5 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KXX73378.1 - 1.4e-48 164.7 0.6 1.4e-48 164.7 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) CBP_BcsG PF11658.8 KXX73378.1 - 0.14 10.6 0.2 0.57 8.5 0.1 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG DEAD_2 PF06733.15 KXX73379.1 - 3e-56 189.8 0.6 5.5e-56 188.9 0.2 1.7 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KXX73379.1 - 9.9e-48 162.3 0.7 2e-43 148.3 0.1 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KXX73379.1 - 2.2e-44 151.7 0.0 9.1e-44 149.6 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KXX73379.1 - 0.00016 21.7 1.6 0.0031 17.5 0.2 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXX73379.1 - 0.00048 18.9 0.0 0.0017 17.1 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KXX73379.1 - 0.0031 17.3 0.0 0.85 9.4 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 KXX73379.1 - 0.096 13.0 0.2 12 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXX73379.1 - 0.61 9.8 4.0 0.99 9.1 0.2 2.5 2 1 0 2 2 2 0 AAA domain DSBA PF01323.20 KXX73380.1 - 1.9e-16 60.4 0.0 2.2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain RNA_pol_Rpb1_5 PF04998.17 KXX73381.1 - 1.1e-89 300.4 0.0 1.8e-89 299.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXX73381.1 - 4.2e-69 232.0 0.1 8.7e-69 231.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXX73381.1 - 8.9e-32 110.2 0.0 2.1e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KXX73381.1 - 1.5e-31 109.9 1.6 7.3e-30 104.4 1.5 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KXX73381.1 - 2.7e-18 65.9 0.0 1.6e-17 63.4 0.0 2.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF4857 PF16149.5 KXX73381.1 - 0.058 12.7 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4857) Histone PF00125.24 KXX73382.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXX73382.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KXX73382.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KXX73382.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXX73382.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXX73382.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXX73382.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNase_E_G PF10150.9 KXX73383.1 - 0.14 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family MMS19_N PF14500.6 KXX73384.1 - 3.3e-55 187.5 0.1 1e-54 185.9 0.1 1.9 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KXX73384.1 - 1.3e-18 67.4 0.1 1.4e-16 60.7 0.0 2.8 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal THF_DHG_CYH PF00763.23 KXX73385.1 - 6.1e-26 91.0 0.1 9.2e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KXX73385.1 - 7.7e-14 51.3 0.0 4.8e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EMC3_TMCO1 PF01956.16 KXX73386.1 - 9e-54 181.7 2.0 1.2e-53 181.3 2.0 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like AmpE PF17113.5 KXX73386.1 - 0.065 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE SPC25 PF06703.11 KXX73387.1 - 3.5e-51 173.2 0.1 4.3e-51 172.9 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RNA_pol_Rbc25 PF08292.12 KXX73388.1 - 2.8e-36 124.6 0.1 5.6e-36 123.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KXX73388.1 - 1.3e-09 38.3 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1_2 PF13509.6 KXX73388.1 - 0.059 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 S1 domain Apq12 PF12716.7 KXX73389.1 - 1.4e-14 53.7 18.0 2.2e-14 53.1 18.0 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF4220 PF13968.6 KXX73389.1 - 0.14 11.5 4.5 0.17 11.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) ATP_bind_1 PF03029.17 KXX73390.1 - 3.2e-74 249.8 0.0 5e-74 249.1 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KXX73390.1 - 0.00019 21.3 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KXX73390.1 - 0.00035 20.6 0.0 0.0012 18.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXX73390.1 - 0.00047 20.5 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KXX73390.1 - 0.00057 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXX73390.1 - 0.005 17.4 0.0 0.012 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXX73390.1 - 0.0099 16.0 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX73390.1 - 0.012 16.0 0.0 0.085 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXX73390.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KXX73390.1 - 0.016 15.3 0.0 0.025 14.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PPV_E1_C PF00519.17 KXX73390.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RsgA_GTPase PF03193.16 KXX73390.1 - 0.028 14.4 0.2 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 KXX73390.1 - 0.037 13.3 0.0 0.087 12.1 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 KXX73390.1 - 0.056 14.0 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KXX73390.1 - 0.058 12.9 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF463 PF04317.12 KXX73390.1 - 0.065 12.1 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 Cytidylate_kin PF02224.18 KXX73390.1 - 0.084 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_29 PF13555.6 KXX73390.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KXX73390.1 - 0.089 12.4 0.1 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.7 KXX73390.1 - 0.091 11.7 0.0 0.39 9.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 KXX73390.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 KXX73390.1 - 0.11 12.1 0.0 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase SRP54 PF00448.22 KXX73390.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KXX73390.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.27 KXX73390.1 - 0.16 11.5 0.0 8.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain S-AdoMet_synt_C PF02773.16 KXX73391.1 - 5.7e-66 220.7 0.3 1e-65 219.9 0.0 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KXX73391.1 - 6.9e-44 149.0 0.0 1.3e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KXX73391.1 - 1.4e-42 144.4 0.2 3.5e-42 143.1 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DUF1996 PF09362.10 KXX73392.1 - 6.4e-80 268.5 0.5 8.7e-80 268.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_12 PF13424.6 KXX73394.1 - 7e-05 23.0 1.4 0.0084 16.4 1.9 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXX73394.1 - 0.0047 16.9 0.3 0.024 14.7 0.3 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX73394.1 - 0.014 15.4 1.8 0.081 13.0 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXX73394.1 - 0.015 15.1 0.3 0.052 13.4 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX73394.1 - 0.21 12.5 4.2 1.3 10.0 0.5 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX73394.1 - 0.3 11.0 4.6 0.33 10.9 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Helicase_C PF00271.31 KXX73396.1 - 9e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXX73396.1 - 0.00023 20.0 0.0 0.0024 16.6 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain CCDC53 PF10152.9 KXX73397.1 - 0.014 15.8 0.7 0.032 14.7 0.7 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2076 PF09849.9 KXX73397.1 - 0.16 12.0 3.9 0.22 11.5 3.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 KXX73397.1 - 1 10.0 7.9 1.9 9.1 7.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cyclin_N PF00134.23 KXX73398.1 - 2e-08 34.0 0.0 4.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Receptor_IA-2 PF11548.8 KXX73398.1 - 0.0065 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase receptor IA-2 Spy1 PF11357.8 KXX73398.1 - 0.08 13.2 0.3 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Cell cycle regulatory protein CECR6_TMEM121 PF14997.6 KXX73398.1 - 0.17 11.7 0.2 0.26 11.1 0.2 1.2 1 0 0 1 1 1 0 CECR6/TMEM121 family CorA PF01544.18 KXX73399.1 - 3.7e-06 26.5 1.4 9.4e-06 25.1 1.4 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NitrOD1 PF18549.1 KXX73399.1 - 0.032 14.2 0.0 0.15 12.0 0.0 2.2 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 VBS PF08913.10 KXX73399.1 - 0.44 11.0 2.8 0.24 11.9 0.4 1.7 2 0 0 2 2 2 0 Vinculin Binding Site FBPase PF00316.20 KXX73401.1 - 1.8e-21 76.5 0.0 2.7e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain SUR7 PF06687.12 KXX73403.1 - 5e-14 52.4 0.8 7.2e-14 51.9 0.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Cupredoxin_1 PF13473.6 KXX73404.1 - 0.0075 16.4 0.2 2.5 8.2 0.1 2.7 2 1 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.20 KXX73404.1 - 0.0075 16.7 0.2 4.7 7.7 0.0 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KXX73404.1 - 0.11 12.5 0.5 12 6.0 0.0 3.0 2 1 0 2 2 2 0 Plastocyanin-like domain GSDH PF07995.11 KXX73407.1 - 3.3e-117 391.5 0.1 3.9e-117 391.3 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 KXX73407.1 - 0.01 15.8 0.0 0.31 11.2 0.0 2.9 3 0 0 3 3 3 0 NHL repeat Reg_prop PF07494.11 KXX73407.1 - 0.024 14.8 6.2 1.8 9.1 0.1 4.4 5 0 0 5 5 5 0 Two component regulator propeller SPC25 PF06703.11 KXX73408.1 - 1.8 8.3 3.9 0.92 9.3 0.4 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) HET PF06985.11 KXX73409.1 - 3.8e-20 72.7 0.0 5.5e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Smac_DIABLO PF09057.10 KXX73410.1 - 0.53 9.6 5.3 0.59 9.5 0.6 2.2 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases Bystin PF05291.11 KXX73411.1 - 5.9e-128 426.2 0.0 7.4e-128 425.9 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF5327 PF17261.2 KXX73411.1 - 0.39 11.5 1.7 1.5 9.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF383 PF04063.14 KXX73412.1 - 1.1e-64 217.6 0.0 4.8e-63 212.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KXX73412.1 - 4.7e-23 80.8 0.9 1e-22 79.7 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Adaptin_N PF01602.20 KXX73412.1 - 0.0094 14.6 0.0 0.017 13.7 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Proteasom_PSMB PF10508.9 KXX73412.1 - 0.031 12.8 0.0 0.58 8.6 0.1 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Sugar_tr PF00083.24 KXX73413.1 - 4.2e-43 147.9 15.8 5.2e-43 147.5 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX73413.1 - 2.9e-19 69.2 26.2 4.3e-19 68.6 26.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-Thr_ED PF08915.11 KXX73413.1 - 0.23 11.5 0.0 0.47 10.5 0.0 1.4 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Fungal_trans PF04082.18 KXX73414.1 - 2.8e-26 92.1 0.0 4.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX73414.1 - 1.4e-06 28.3 13.6 2.2e-06 27.7 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXX73415.1 - 2e-28 99.3 17.8 6.4e-19 68.1 1.4 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX73415.1 - 4.4e-09 35.7 0.8 4.4e-09 35.7 0.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXX73415.1 - 9.3e-05 21.5 0.0 0.004 16.1 0.0 2.8 1 1 1 2 2 2 2 MFS_1 like family dCMP_cyt_deam_1 PF00383.23 KXX73416.1 - 9.1e-11 41.5 0.1 1.5e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXX73416.1 - 0.00014 21.7 0.2 0.00037 20.3 0.1 1.7 2 0 0 2 2 2 1 MafB19-like deaminase Na_H_Exchanger PF00999.21 KXX73417.1 - 4.5e-11 42.2 5.3 1.9e-10 40.1 2.3 2.2 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Ank PF00023.30 KXX73417.1 - 0.062 13.8 0.0 13 6.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 KXX73418.1 - 1.2e-15 57.4 1.0 1.7e-12 47.3 0.4 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX73418.1 - 6.8e-12 45.8 0.1 1.2e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 KXX73418.1 - 3.3e-11 43.1 0.0 1.2e-10 41.3 0.1 2.0 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 KXX73418.1 - 1.2e-10 41.7 2.8 1.9e-06 28.3 0.5 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73418.1 - 5.6e-10 38.6 0.8 4e-06 26.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KXX73418.1 - 9e-10 38.6 2.8 7.1e-07 29.4 0.3 2.8 2 0 0 2 2 2 2 Ankyrin repeat Haem_degrading PF03928.14 KXX73418.1 - 0.051 13.6 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Haem-degrading Matrilin_ccoil PF10393.9 KXX73418.1 - 0.12 12.3 1.0 0.27 11.1 1.0 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin 6PF2K PF01591.18 KXX73420.1 - 4.8e-62 209.2 0.0 4.3e-40 137.4 0.0 3.2 2 1 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXX73420.1 - 2.2e-28 99.3 0.0 5.7e-25 88.2 0.0 2.6 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXX73420.1 - 0.0031 17.7 0.0 0.059 13.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain DDE_3 PF13358.6 KXX73420.1 - 0.028 14.2 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease KTI12 PF08433.10 KXX73420.1 - 0.048 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CARD PF00619.21 KXX73420.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Val_tRNA-synt_C PF10458.9 KXX73420.1 - 0.11 12.9 0.1 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm IPK PF03770.16 KXX73423.1 - 6.2e-57 192.7 0.0 1e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 KXX73423.1 - 0.034 14.0 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 ATG27 PF09451.10 KXX73424.1 - 1.5e-96 323.3 0.0 1.8e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 DUF4637 PF15470.6 KXX73424.1 - 0.073 12.8 1.8 0.078 12.7 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) ECH_1 PF00378.20 KXX73425.1 - 4.7e-19 68.7 0.0 5.3e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX73425.1 - 2.4e-05 24.0 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXX73425.1 - 0.073 13.0 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 TruB_C PF09142.11 KXX73426.1 - 0.16 11.8 2.6 0.46 10.3 2.6 1.8 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Spt20 PF12090.8 KXX73427.1 - 1.2e-52 178.9 0.0 1.2e-52 178.9 0.0 9.1 4 2 1 5 5 5 1 Spt20 family zf-RING_2 PF13639.6 KXX73428.1 - 2.8e-12 46.8 4.9 4.6e-12 46.1 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXX73428.1 - 2.6e-10 39.9 1.9 5.2e-10 38.9 1.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXX73428.1 - 3.6e-07 30.0 3.5 5.8e-07 29.3 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX73428.1 - 1.4e-06 28.1 4.6 2.2e-06 27.4 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX73428.1 - 1.2e-05 25.4 5.5 3.5e-05 24.0 5.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXX73428.1 - 3.7e-05 23.6 1.4 6.2e-05 22.9 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXX73428.1 - 8.6e-05 22.3 4.8 0.00015 21.6 4.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXX73428.1 - 0.0039 17.2 4.2 0.004 17.1 2.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXX73428.1 - 0.015 15.4 1.8 0.029 14.4 1.4 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXX73428.1 - 0.029 14.2 1.7 0.061 13.2 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KXX73428.1 - 0.16 12.3 1.0 0.26 11.6 1.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KXX73428.1 - 0.51 10.2 3.1 0.89 9.4 3.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Dicty_REP PF05086.12 KXX73428.1 - 2.6 5.9 3.1 3.7 5.4 3.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleo_P87 PF07267.11 KXX73428.1 - 8.8 5.0 8.0 13 4.5 8.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_cc PF11790.8 KXX73429.1 - 9.8e-58 195.5 0.2 1.3e-57 195.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1180 PF06679.12 KXX73429.1 - 1.4 9.3 3.1 2.8 8.3 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mito_fiss_reg PF05308.11 KXX73429.1 - 2 8.4 7.8 3 7.9 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KXX73429.1 - 4.7 7.3 13.3 8.2 6.5 13.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Zn_clus PF00172.18 KXX73430.1 - 2.4e-08 33.9 9.0 4.1e-08 33.2 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_GLY PF01302.25 KXX73431.1 - 4.5e-21 74.6 1.9 6.3e-21 74.2 1.9 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KXX73431.1 - 1.6e-17 63.7 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KXX73431.1 - 8.7e-06 25.4 0.0 2.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family T6_Ig_like PF18002.1 KXX73431.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 T6 antigen Ig like domain Saf_2TM PF18303.1 KXX73432.1 - 0.33 10.5 1.2 0.64 9.6 1.1 1.6 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain Bromodomain PF00439.25 KXX73434.1 - 2.9e-24 84.9 0.2 4.9e-24 84.2 0.2 1.3 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXX73434.1 - 1.4e-07 31.7 0.1 3.1e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX73434.1 - 6.9e-07 29.2 0.3 1.6e-06 28.1 0.2 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX73434.1 - 0.00041 20.7 0.1 0.00087 19.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_MOT1 PF16983.5 KXX73435.1 - 5.8e-62 207.0 33.1 2.9e-34 117.8 14.7 2.3 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KXX73435.1 - 5.2e-06 25.5 0.2 5.2e-06 25.5 0.2 2.5 2 1 0 2 2 2 2 Sulfate permease family DUF3638 PF12340.8 KXX73436.1 - 8.1e-87 290.3 0.0 1.3e-86 289.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXX73436.1 - 9.5e-16 56.9 0.1 2e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Fer4_19 PF06902.11 KXX73436.1 - 0.11 12.5 0.2 2.2 8.4 0.1 2.8 3 0 0 3 3 3 0 Divergent 4Fe-4S mono-cluster DUF4239 PF14023.6 KXX73437.1 - 0.1 12.3 0.2 0.1 12.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) eIF3_N PF09440.10 KXX73438.1 - 6.8e-49 165.7 1.8 2.6e-47 160.6 4.4 2.2 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KXX73438.1 - 1.8e-14 54.1 0.1 4.3e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 PCI domain Caprin-1_dimer PF18293.1 KXX73438.1 - 0.047 14.2 0.7 0.13 12.7 0.1 2.1 2 0 0 2 2 2 0 Caprin-1 dimerization domain ANAPC1 PF12859.7 KXX73439.1 - 1.1e-39 135.9 0.4 2.9e-39 134.6 0.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KXX73439.1 - 5.5e-06 26.5 0.1 0.035 14.6 0.0 4.3 3 0 0 3 3 3 1 Proteasome/cyclosome repeat ARID PF01388.21 KXX73440.1 - 3.5e-17 62.8 2.0 3.7e-17 62.8 0.1 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Img2 PF05046.14 KXX73441.1 - 6.1e-27 93.7 0.1 7.8e-27 93.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 KXX73441.1 - 0.00055 20.4 0.5 0.0014 19.1 0.5 1.7 1 1 0 1 1 1 1 Translation initiation factor SUI1 Hamartin PF04388.12 KXX73441.1 - 0.15 10.7 1.1 0.15 10.7 1.1 1.1 1 0 0 1 1 1 0 Hamartin protein Clathrin PF00637.20 KXX73442.1 - 1.6e-15 57.3 1.0 4.7e-15 55.7 0.2 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS Caldesmon PF02029.15 KXX73442.1 - 4.4e-05 22.4 31.2 6.9e-05 21.8 31.2 1.2 1 0 0 1 1 1 1 Caldesmon SDA1 PF05285.12 KXX73442.1 - 0.00051 19.6 49.6 0.001 18.6 49.6 1.4 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 KXX73442.1 - 0.015 13.6 36.3 0.04 12.2 36.3 1.6 1 0 0 1 1 1 0 CDC45-like protein zf-RING_5 PF14634.6 KXX73442.1 - 0.036 14.0 0.4 0.036 14.0 0.4 1.7 2 0 0 2 2 2 0 zinc-RING finger domain RR_TM4-6 PF06459.12 KXX73442.1 - 0.067 13.0 29.6 0.12 12.1 29.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.32 KXX73442.1 - 0.14 13.1 0.3 14 6.7 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Nop14 PF04147.12 KXX73442.1 - 0.19 9.9 59.3 0.41 8.8 59.3 1.5 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KXX73442.1 - 7.5 4.9 58.8 16 3.8 58.8 1.5 1 0 0 1 1 1 0 Mpp10 protein GST_N PF02798.20 KXX73443.1 - 7.1e-11 42.3 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXX73443.1 - 1.8e-07 31.3 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX73443.1 - 2.6e-07 30.7 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX73443.1 - 7.5e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX73443.1 - 0.00027 20.9 0.0 0.00042 20.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXX73443.1 - 0.0003 21.0 0.0 0.00058 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3686 PF12458.8 KXX73443.1 - 0.14 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 ATPase involved in DNA repair HET PF06985.11 KXX73444.1 - 5.9e-05 23.4 0.0 9.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cu-oxidase_2 PF07731.14 KXX73444.1 - 0.011 15.5 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase SKIP_SNW PF02731.15 KXX73445.1 - 4.5e-59 198.7 3.5 4.5e-59 198.7 3.5 2.9 3 0 0 3 3 3 1 SKIP/SNW domain DUF4603 PF15376.6 KXX73445.1 - 4 4.7 14.5 5.2 4.3 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Tim17 PF02466.19 KXX73447.1 - 1.7e-36 124.9 10.5 2.6e-36 124.4 10.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_16 PF00722.21 KXX73448.1 - 5.9e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BCDHK_Adom3 PF10436.9 KXX73449.1 - 6e-47 159.5 1.3 1.2e-46 158.5 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXX73449.1 - 1.2e-06 29.0 0.1 1.1e-05 25.9 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXX73449.1 - 0.026 14.3 0.1 0.081 12.8 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SR-25 PF10500.9 KXX73449.1 - 0.11 12.1 4.9 0.18 11.4 4.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein USP7_ICP0_bdg PF12436.8 KXX73450.1 - 3.9e-89 298.1 0.0 8e-87 290.5 0.0 2.9 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KXX73450.1 - 2.2e-76 256.2 2.2 2.1e-72 243.2 0.2 3.6 3 0 0 3 3 3 3 Ubiquitin-specific protease C-terminal UCH PF00443.29 KXX73450.1 - 1.6e-48 165.4 2.0 3.9e-48 164.2 1.7 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX73450.1 - 5e-21 75.6 0.4 1.2e-20 74.3 0.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KXX73450.1 - 9.1e-12 45.1 0.1 3e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 MATH domain Malt_amylase_C PF16657.5 KXX73450.1 - 0.037 14.2 0.1 8.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain WD40 PF00400.32 KXX73451.1 - 2.5e-45 151.5 24.3 1.5e-08 35.1 0.1 13.2 14 0 0 14 14 14 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX73451.1 - 1.6e-24 86.0 0.0 0.0013 19.0 0.0 9.9 5 1 5 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KXX73451.1 - 3.5e-15 56.2 0.0 5.4e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KXX73451.1 - 5.7e-10 38.7 2.1 0.43 9.5 0.0 6.0 4 3 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXX73451.1 - 2.2e-07 31.0 2.8 0.023 14.6 0.1 6.2 4 2 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXX73451.1 - 9.5e-06 25.1 0.0 0.084 12.2 0.0 3.6 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 KXX73451.1 - 0.00023 20.0 2.1 1.8 7.1 0.0 4.1 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXX73451.1 - 0.0012 18.2 0.3 9.3 5.5 0.0 4.2 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KXX73451.1 - 0.017 14.1 0.0 1.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 KXX73451.1 - 0.04 14.4 0.2 55 4.4 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain PD40 PF07676.12 KXX73451.1 - 0.048 13.6 1.3 22 5.1 0.0 4.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Septin PF00735.18 KXX73452.1 - 4.2e-115 383.9 0.4 5.9e-115 383.4 0.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXX73452.1 - 2.1e-07 31.0 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXX73452.1 - 4.1e-06 26.5 3.4 7.7e-05 22.3 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXX73452.1 - 6.3e-06 26.2 1.8 3e-05 24.0 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KXX73452.1 - 0.0017 18.6 0.7 0.0053 17.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KXX73452.1 - 0.0026 17.3 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KXX73452.1 - 0.0036 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXX73452.1 - 0.0077 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KXX73452.1 - 0.0087 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 KXX73452.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Casc1_N PF15927.5 KXX73452.1 - 0.017 14.8 10.5 0.047 13.4 10.5 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ras PF00071.22 KXX73452.1 - 0.019 14.5 0.6 0.062 12.9 0.5 1.9 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.6 KXX73452.1 - 0.027 14.8 1.8 0.086 13.2 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 KXX73452.1 - 0.034 13.4 0.0 0.044 13.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 KXX73452.1 - 0.042 12.9 0.4 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KXX73452.1 - 0.052 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FOXP-CC PF16159.5 KXX73452.1 - 0.055 14.1 1.0 0.055 14.1 1.0 2.4 2 1 0 2 2 1 0 FOXP coiled-coil domain ABC_tran PF00005.27 KXX73452.1 - 0.056 14.0 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KXX73452.1 - 0.079 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Val_tRNA-synt_C PF10458.9 KXX73452.1 - 0.086 13.1 1.0 0.086 13.1 1.0 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PduV-EutP PF10662.9 KXX73452.1 - 0.14 11.9 0.4 8.3 6.2 0.1 2.6 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KXX73452.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 KXX73452.1 - 0.37 10.8 6.4 4.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 KXX73452.1 - 0.98 10.0 6.0 7.8 7.1 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e DivIC PF04977.15 KXX73452.1 - 1.8 8.4 6.7 0.63 9.8 2.1 2.5 2 0 0 2 2 2 0 Septum formation initiator AAA_11 PF13086.6 KXX73452.1 - 2.4 7.8 6.3 22 4.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myc-LZ PF02344.15 KXX73452.1 - 7.1 6.8 11.7 11 6.2 5.4 3.3 2 1 0 2 2 2 0 Myc leucine zipper domain adh_short PF00106.25 KXX73454.1 - 3.5e-26 91.9 0.0 5.3e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73454.1 - 2.9e-14 53.2 0.0 4.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73454.1 - 0.028 14.3 1.6 0.069 13.1 1.6 1.6 1 1 0 1 1 1 0 KR domain AAA PF00004.29 KXX73455.1 - 1.7e-14 54.4 0.0 4.7e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX73455.1 - 0.0007 20.0 0.2 0.0024 18.3 0.1 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXX73455.1 - 0.0038 17.2 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX73455.1 - 0.023 15.0 0.6 0.4 11.0 0.3 2.6 1 1 1 2 2 2 0 AAA domain CPT PF07931.12 KXX73455.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 KXX73455.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Response_reg PF00072.24 KXX73456.1 - 5e-20 71.8 0.0 9.4e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KXX73456.1 - 4.2e-19 69.1 0.1 1.1e-18 67.7 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXX73456.1 - 4.9e-09 36.1 0.5 1.3e-08 34.7 0.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Senescence PF06911.12 KXX73458.1 - 0.0064 16.8 0.2 0.0074 16.6 0.2 1.0 1 0 0 1 1 1 1 Senescence-associated protein Ank_2 PF12796.7 KXX73459.1 - 2.9e-15 56.6 0.0 1.7e-08 34.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX73459.1 - 5.5e-12 45.9 0.0 0.00022 21.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73459.1 - 5.1e-09 35.7 4.3 0.0099 16.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXX73459.1 - 5.7e-08 32.9 7.8 0.00078 19.7 0.2 4.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KXX73459.1 - 1.6e-05 25.1 1.6 0.0073 16.7 0.0 4.2 5 0 0 5 5 5 1 Ankyrin repeat TetR_C_13 PF16925.5 KXX73460.1 - 0.076 12.9 0.5 0.1 12.6 0.5 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ketoacyl-synt PF00109.26 KXX73461.1 - 2.5e-19 69.9 0.0 1.3e-10 41.3 0.0 2.1 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_114 PF03537.13 KXX73462.1 - 8.4e-50 169.2 0.2 1e-49 169.0 0.2 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Helo_like_N PF17111.5 KXX73463.1 - 4.6e-09 35.9 1.5 7.4e-09 35.3 1.5 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SGTA_dimer PF16546.5 KXX73464.1 - 1.1e-26 92.4 0.5 2e-26 91.6 0.5 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KXX73464.1 - 2.9e-16 58.5 6.7 1.2e-06 28.0 0.7 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX73464.1 - 3.1e-14 51.8 9.1 8.5e-06 25.5 0.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXX73464.1 - 1.5e-09 37.4 4.7 4.5e-05 23.1 1.7 3.3 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KXX73464.1 - 1.3e-08 34.4 6.7 0.098 12.9 0.1 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXX73464.1 - 1.2e-07 32.0 11.5 0.0051 17.5 0.1 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXX73464.1 - 2.1e-07 31.3 4.2 3.8e-05 24.1 2.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXX73464.1 - 2.6e-07 30.5 5.1 0.00097 19.4 0.3 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX73464.1 - 5.5e-06 26.9 17.9 0.00031 21.3 4.6 3.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX73464.1 - 6.7e-06 25.8 0.9 0.006 16.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX73464.1 - 8.4e-06 26.0 5.9 3e-05 24.2 4.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 KXX73464.1 - 0.00042 20.2 7.7 0.00084 19.2 3.9 2.4 2 0 0 2 2 2 1 STI1 domain TPR_9 PF13371.6 KXX73464.1 - 0.00048 20.2 0.8 0.017 15.3 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 KXX73464.1 - 0.0018 18.8 2.7 1.1 9.7 0.4 2.5 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 KXX73464.1 - 0.0038 17.0 6.2 0.18 11.7 0.8 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.11 KXX73464.1 - 0.021 14.5 1.2 0.049 13.4 1.2 1.6 1 0 0 1 1 1 0 XPC-binding domain DUF3446 PF11928.8 KXX73464.1 - 0.028 14.7 1.0 0.028 14.7 1.0 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain TPR_6 PF13174.6 KXX73464.1 - 0.19 12.4 8.1 4.7 8.1 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FAA_hydrolase PF01557.18 KXX73465.1 - 3.2e-14 53.1 0.0 3.6e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 KXX73466.1 - 1.9e-25 89.2 0.0 2.1e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase TPP_enzyme_C PF02775.21 KXX73467.1 - 8.8e-51 171.7 0.5 1.3e-49 167.9 0.1 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXX73467.1 - 7.4e-41 139.1 1.5 1.5e-40 138.1 0.3 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 KXX73467.1 - 1.2e-38 132.4 1.6 4e-38 130.7 0.2 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain GATase_5 PF13507.6 KXX73468.1 - 5.7e-101 337.0 0.0 8.4e-101 336.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KXX73468.1 - 8.2e-36 123.5 1.2 8.6e-25 87.7 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KXX73468.1 - 4.7e-24 84.6 0.0 8.5e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KXX73468.1 - 3.6e-22 78.6 0.1 9.9e-22 77.2 0.1 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain SpdB PF05122.13 KXX73468.1 - 0.098 12.8 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Mobile element transfer protein zf-BED PF02892.15 KXX73469.1 - 0.028 14.4 0.8 0.094 12.8 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger DUF4451 PF14616.6 KXX73469.1 - 1.6 8.9 5.5 4.7 7.4 5.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-C2H2 PF00096.26 KXX73469.1 - 2.2 8.9 12.0 0.74 10.4 0.4 4.3 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 KXX73469.1 - 2.4 8.5 10.1 0.89 9.9 2.8 2.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GalKase_gal_bdg PF10509.9 KXX73470.1 - 8.1e-19 66.9 0.0 1.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KXX73470.1 - 7.6e-15 54.9 3.2 2.9e-14 53.0 2.5 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXX73470.1 - 7.9e-13 48.6 0.0 2.3e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.12 KXX73470.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 RINGv PF12906.7 KXX73471.1 - 6.4e-05 23.0 7.3 0.00011 22.2 7.3 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KXX73471.1 - 0.00022 21.4 4.0 0.0004 20.5 4.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KXX73471.1 - 0.00058 20.2 7.3 0.00094 19.5 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain Spt20 PF12090.8 KXX73471.1 - 0.15 11.6 4.2 0.23 11.0 4.2 1.2 1 0 0 1 1 1 0 Spt20 family PHD_Oberon PF07227.11 KXX73471.1 - 0.2 11.5 1.8 0.33 10.9 1.8 1.2 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein zf-RING_4 PF14570.6 KXX73471.1 - 0.41 10.5 4.4 0.76 9.6 4.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1180 PF06679.12 KXX73471.1 - 1.3 9.4 8.7 0.7 10.3 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Menin PF05053.13 KXX73471.1 - 2.4 6.4 4.1 3.6 5.8 4.1 1.2 1 0 0 1 1 1 0 Menin zf-C3HC4 PF00097.25 KXX73471.1 - 3.7 7.5 6.0 6 6.8 6.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX73471.1 - 6.4 6.7 6.6 17 5.3 6.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FNIP_N PF14636.6 KXX73472.1 - 3.7e-45 154.6 0.6 3.7e-45 154.6 0.6 4.5 4 0 0 4 4 4 1 Folliculin-interacting protein N-terminus Zn_clus PF00172.18 KXX73473.1 - 4.8e-09 36.2 7.9 4.8e-09 36.2 7.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactonase PF10282.9 KXX73474.1 - 3.6e-81 273.1 0.0 4.1e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NTPase_I-T PF01931.18 KXX73475.1 - 2.2e-55 186.9 0.0 2.5e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 GH43_C2 PF17851.1 KXX73476.1 - 2.1e-22 79.9 0.0 3.4e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_43 PF04616.14 KXX73476.1 - 5.3e-21 75.2 0.7 8.3e-21 74.5 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DnaJ PF00226.31 KXX73477.1 - 8.2e-20 70.7 2.1 1.3e-19 70.0 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KXX73477.1 - 0.034 14.4 0.5 0.052 13.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF4875 PF16175.5 KXX73477.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) Tyrosinase PF00264.20 KXX73478.1 - 2e-47 162.3 0.4 2.6e-47 162.0 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase GMC_oxred_N PF00732.19 KXX73479.1 - 4.3e-47 160.9 0.0 5.7e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KXX73479.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXX73479.1 - 0.002 18.3 0.2 0.036 14.3 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GMC_oxred_C PF05199.13 KXX73479.1 - 0.0046 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXX73479.1 - 0.0059 15.7 0.2 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXX73479.1 - 0.048 12.7 0.0 5.2 6.0 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain PRR20 PF15708.5 KXX73480.1 - 0.005 16.8 4.2 0.005 16.8 4.2 2.1 1 1 1 2 2 2 1 Proline-rich protein family 20 SpoIIP PF07454.11 KXX73480.1 - 0.0076 15.7 1.7 0.0076 15.7 1.7 1.5 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) DUF2722 PF10846.8 KXX73480.1 - 0.0091 15.0 10.2 0.013 14.5 10.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Plasmodium_Vir PF05795.11 KXX73480.1 - 0.23 10.9 0.7 0.3 10.4 0.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein UPF0524 PF15823.5 KXX73480.1 - 0.24 10.7 2.5 0.48 9.8 2.5 1.5 1 0 0 1 1 1 0 UPF0524 of C3orf70 Presenilin PF01080.17 KXX73480.1 - 0.3 9.8 6.8 0.44 9.3 6.8 1.2 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.6 KXX73480.1 - 0.45 11.0 6.8 0.6 10.6 6.8 1.2 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 KXX73480.1 - 0.59 9.9 2.0 0.99 9.1 2.0 1.3 1 0 0 1 1 1 0 Connexin BssS PF13991.6 KXX73480.1 - 1 9.5 6.3 0.36 10.9 1.6 2.6 2 1 1 3 3 3 0 BssS protein family LMBR1 PF04791.16 KXX73480.1 - 1.2 8.0 2.1 1.2 7.9 2.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spt20 PF12090.8 KXX73480.1 - 1.5 8.4 24.5 0.16 11.5 19.7 1.8 3 0 0 3 3 3 0 Spt20 family Terpene_synth_C PF03936.16 KXX73481.1 - 0.00016 21.1 0.2 0.00026 20.4 0.2 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ANTAR PF03861.14 KXX73481.1 - 0.12 12.3 1.3 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 ANTAR domain p450 PF00067.22 KXX73482.1 - 1.1e-43 149.7 0.0 1.1e-41 143.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.31 KXX73483.1 - 6.3e-10 39.0 0.7 1.3e-09 38.0 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4269 PF14091.6 KXX73484.1 - 0.023 15.0 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) YdaS_antitoxin PF15943.5 KXX73484.1 - 0.13 12.2 0.0 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Tho1_MOS11_C PF18592.1 KXX73485.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain Ank_4 PF13637.6 KXX73485.1 - 0.15 12.7 0.0 9.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) GATA PF00320.27 KXX73486.1 - 1.9e-16 59.4 2.3 3.6e-16 58.5 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KXX73486.1 - 2.3e-09 36.9 0.2 5.7e-09 35.7 0.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CFEM PF05730.11 KXX73487.1 - 0.0088 16.1 3.5 0.017 15.2 3.5 1.5 1 0 0 1 1 1 1 CFEM domain Pkinase PF00069.25 KXX73488.1 - 1.3e-60 205.0 0.0 9.9e-60 202.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73488.1 - 2.9e-28 98.9 0.2 4.4e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KXX73488.1 - 0.00038 21.1 3.7 0.00068 20.3 1.4 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXX73488.1 - 0.0041 16.5 0.3 0.016 14.5 0.0 2.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KXX73488.1 - 0.0053 16.7 0.1 0.13 12.2 0.1 3.0 3 1 1 4 4 4 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXX73488.1 - 0.042 12.8 0.0 0.077 11.9 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXX73488.1 - 0.042 13.2 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Wbp11 PF09429.10 KXX73489.1 - 1.1e-23 83.4 16.4 1.1e-23 83.4 16.4 2.0 3 0 0 3 3 3 1 WW domain binding protein 11 ICAT PF06384.11 KXX73489.1 - 0.048 13.9 2.3 0.37 11.1 0.6 2.3 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Lipoprotein_7 PF01540.16 KXX73489.1 - 0.089 12.1 5.4 0.13 11.5 5.4 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein FAD_binding_3 PF01494.19 KXX73490.1 - 9e-45 153.4 0.0 1.4e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX73490.1 - 3.8e-06 26.7 0.1 0.0033 17.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX73490.1 - 1.1e-05 24.8 0.0 3.2e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX73490.1 - 2.6e-05 24.3 0.1 6.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXX73490.1 - 0.00029 21.4 0.1 0.17 12.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX73490.1 - 0.0011 17.7 0.1 0.0037 16.0 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KXX73490.1 - 0.0068 15.5 0.2 0.019 14.0 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KXX73490.1 - 0.027 13.3 0.6 2.4 6.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KXX73490.1 - 0.033 13.4 0.1 0.078 12.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KXX73490.1 - 0.05 13.6 0.5 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXX73490.1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CFEM PF05730.11 KXX73491.1 - 2.5e-13 49.9 9.9 4.7e-13 49.0 9.9 1.4 1 0 0 1 1 1 1 CFEM domain COX4 PF02936.14 KXX73491.1 - 0.19 11.7 0.1 0.46 10.5 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF1857 PF08982.11 KXX73493.1 - 8.2e-55 184.7 0.2 9.9e-55 184.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Pro_CA PF00484.19 KXX73494.1 - 0.00017 21.9 0.1 0.00029 21.2 0.1 1.3 1 1 0 1 1 1 1 Carbonic anhydrase SAM_decarbox PF01536.16 KXX73495.1 - 7.7e-136 452.8 0.0 9.3e-136 452.5 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.9 KXX73497.1 - 2.1e-92 309.1 0.0 2.6e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXX73497.1 - 5.2e-11 42.7 0.0 1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KXX73497.1 - 1.3e-06 27.9 0.0 1.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KXX73497.1 - 6.2e-06 26.2 0.0 0.0003 20.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KXX73497.1 - 8.5e-06 25.2 0.6 1.6e-05 24.2 0.3 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 KXX73497.1 - 0.00029 19.9 0.4 0.00047 19.2 0.4 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KXX73497.1 - 0.0016 18.0 0.2 0.0033 17.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KXX73497.1 - 0.0044 16.5 0.1 0.014 14.9 0.1 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KXX73497.1 - 0.0056 16.5 0.4 3.9 7.2 0.3 2.4 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 KXX73497.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KXX73497.1 - 0.031 13.6 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KXX73497.1 - 0.036 14.4 0.2 0.085 13.2 0.2 1.6 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 KXX73497.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 KXX73497.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KXX73497.1 - 0.47 10.3 2.1 0.6 10.0 1.1 1.6 2 0 0 2 2 2 0 RsgA GTPase Transferase PF02458.15 KXX73498.1 - 1.3e-12 47.1 0.0 3.6e-06 25.9 0.0 3.0 2 1 1 3 3 3 3 Transferase family p450 PF00067.22 KXX73499.1 - 3.6e-91 306.3 0.0 4.1e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_1b PF00579.25 KXX73501.1 - 0.19 11.0 0.0 14 4.8 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Spherulin4 PF12138.8 KXX73503.1 - 8.6e-33 114.0 0.1 7.8e-31 107.6 0.1 2.0 1 1 0 1 1 1 1 Spherulation-specific family 4 NACHT PF05729.12 KXX73504.1 - 0.0033 17.3 0.1 0.26 11.2 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_29 PF13555.6 KXX73504.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KXX73504.1 - 0.015 15.8 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXX73504.1 - 0.021 15.3 0.1 0.22 12.0 0.0 2.3 2 1 1 3 3 3 0 ABC transporter RNA_helicase PF00910.22 KXX73504.1 - 0.028 14.8 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MeaB PF03308.16 KXX73504.1 - 0.047 12.7 0.0 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KXX73504.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KXX73504.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 KXX73504.1 - 0.23 11.8 0.9 2.8 8.3 0.1 2.8 2 1 1 3 3 3 0 AAA ATPase domain Glyco_hydro_43 PF04616.14 KXX73505.1 - 1.7e-64 217.9 3.0 2.2e-64 217.6 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXX73505.1 - 3.8e-20 72.5 0.0 9.7e-20 71.1 0.0 1.6 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain p450 PF00067.22 KXX73506.1 - 9.5e-33 113.6 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B_2 PF12706.7 KXX73507.1 - 7.5e-08 32.1 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXX73507.1 - 0.00028 20.9 0.0 0.0018 18.4 0.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.14 KXX73507.1 - 0.00029 21.0 0.0 0.00081 19.6 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 KXX73507.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Glyco_hydro_43 PF04616.14 KXX73508.1 - 0.0052 16.1 0.2 0.011 15.1 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KXX73508.1 - 0.13 11.8 0.0 0.54 9.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Zn_clus PF00172.18 KXX73509.1 - 1.7e-08 34.5 11.8 2.6e-08 33.8 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pantoate_transf PF02548.15 KXX73510.1 - 4.1e-108 360.7 0.3 4.7e-108 360.5 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KXX73510.1 - 3e-10 40.0 0.7 3.9e-10 39.6 0.1 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PA PF02225.22 KXX73510.1 - 0.13 12.3 0.8 0.56 10.3 0.3 2.1 2 0 0 2 2 2 0 PA domain APG12 PF04110.13 KXX73511.1 - 1.2e-25 89.7 0.0 1.6e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KXX73511.1 - 9.5e-05 22.5 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like DUF572 PF04502.13 KXX73512.1 - 2.3e-66 224.7 0.0 2.5e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1778 PF08681.11 KXX73512.1 - 0.012 15.5 0.3 0.032 14.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) DUF2526 PF10735.9 KXX73512.1 - 0.27 11.4 2.5 0.5 10.6 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) UQ_con PF00179.26 KXX73513.1 - 1.6e-35 121.8 0.1 2e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ApbA PF02558.16 KXX73514.1 - 2.9e-23 82.2 0.0 4.3e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXX73514.1 - 2e-21 76.5 0.0 3.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 KXX73515.1 - 2.8e-21 75.6 6.2 4.5e-21 74.9 6.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like EAP30 PF04157.16 KXX73515.1 - 0.0038 16.6 1.3 0.004 16.5 1.3 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family BBS2_C PF14782.6 KXX73515.1 - 0.015 14.1 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal MalF_P2 PF14785.6 KXX73515.1 - 0.049 13.7 0.2 0.055 13.5 0.2 1.0 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Rpr2 PF04032.16 KXX73516.1 - 1e-22 80.2 0.0 1.4e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.29 KXX73517.1 - 2e-39 135.2 0.0 3.3e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX73517.1 - 2.9e-25 88.8 0.2 1e-23 83.8 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX73517.1 - 1.6e-08 34.8 0.0 3.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KXX73517.1 - 0.1 13.2 0.4 0.26 11.8 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Cyclin PF08613.11 KXX73518.1 - 6.9e-06 26.5 0.1 6.9e-06 26.5 0.1 2.5 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KXX73518.1 - 0.0097 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain CDV3 PF15359.6 KXX73518.1 - 1.3 9.6 4.5 0.89 10.0 1.2 2.2 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 MFS_1 PF07690.16 KXX73519.1 - 1.4e-38 132.7 47.6 1.4e-38 132.7 47.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX73519.1 - 2e-11 43.4 12.0 2e-11 43.4 12.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KXX73519.1 - 9.3e-08 30.9 24.1 1.3e-07 30.4 24.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRAP-gamma PF07074.12 KXX73519.1 - 1.2 8.6 3.3 3.6 7.1 0.3 2.5 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) UbiA PF01040.18 KXX73520.1 - 1.6e-25 89.9 2.0 2.1e-25 89.5 1.5 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Flu_M2 PF00599.17 KXX73521.1 - 0.22 11.6 2.1 0.45 10.6 0.4 2.3 1 1 1 2 2 2 0 Influenza Matrix protein (M2) p450 PF00067.22 KXX73522.1 - 2.6e-55 188.0 0.0 3.2e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KXX73523.1 - 8.6e-60 202.6 0.0 1.2e-59 202.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX73523.1 - 2.2e-30 106.1 0.1 6.9e-30 104.5 0.1 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX73523.1 - 9.3e-10 38.1 0.0 1.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXX73523.1 - 5.4e-08 32.3 0.1 1.7e-07 30.7 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX73523.1 - 3.9e-05 23.0 0.0 0.00029 20.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX73523.1 - 5.6e-05 23.3 0.1 0.00018 21.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXX73523.1 - 0.00026 20.3 0.2 0.00049 19.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXX73523.1 - 0.00049 19.5 0.1 0.023 14.0 0.1 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX73523.1 - 0.00051 19.7 2.8 0.00051 19.7 2.8 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX73523.1 - 0.0017 17.1 0.3 0.0038 16.0 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.18 KXX73523.1 - 0.0026 18.0 0.6 0.015 15.6 0.1 2.4 3 0 0 3 3 3 1 TrkA-N domain Pyr_redox PF00070.27 KXX73523.1 - 0.0038 17.7 0.0 0.037 14.6 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX73523.1 - 0.013 14.8 0.0 0.08 12.2 0.0 2.1 2 1 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 KXX73523.1 - 0.016 14.4 0.0 0.044 12.9 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KXX73523.1 - 0.032 13.1 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KXX73523.1 - 0.038 14.0 1.0 0.16 11.9 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_4 PF01565.23 KXX73524.1 - 5.1e-25 87.8 1.6 9.3e-25 87.0 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain CNH PF00780.22 KXX73527.1 - 2.5e-76 256.9 0.0 8.8e-76 255.1 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KXX73527.1 - 2.1e-41 141.2 1.4 8.6e-41 139.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 KXX73527.1 - 4.8e-34 118.2 0.0 1e-33 117.1 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KXX73527.1 - 6.4e-16 58.2 0.1 1.2e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SH3_1 PF00018.28 KXX73528.1 - 7.1e-14 51.1 0.1 1.1e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX73528.1 - 3.6e-10 39.5 0.1 6.6e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX73528.1 - 5.3e-08 32.4 0.0 7.7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SHOCT PF09851.9 KXX73528.1 - 0.042 13.6 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Short C-terminal domain ATP-synt_C PF00137.21 KXX73530.1 - 4.2e-29 100.7 37.3 5.8e-18 65.0 14.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Metallophos PF00149.28 KXX73531.1 - 4.5e-09 37.1 3.5 9e-09 36.1 2.8 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase B12-binding PF02310.19 KXX73531.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain DLH PF01738.18 KXX73532.1 - 1.6e-20 73.6 0.1 4.7e-19 68.8 0.1 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KXX73532.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXX73532.1 - 0.14 11.8 0.0 0.96 9.0 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 KXX73533.1 - 1.7e-24 86.3 0.2 2.6e-24 85.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX73533.1 - 1.1e-22 81.5 0.0 1.8e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX73533.1 - 3.7e-09 36.4 0.0 6.2e-08 32.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain CDT1_C PF16679.5 KXX73534.1 - 7.7e-26 90.4 0.6 2.4e-25 88.8 0.6 1.9 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Isy1 PF06246.12 KXX73535.1 - 5.2e-88 294.9 0.4 6.4e-88 294.6 0.4 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 KXX73535.1 - 0.0033 17.4 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 YolD-like protein CybS PF05328.12 KXX73536.1 - 7.5e-47 158.4 0.0 9.3e-47 158.1 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 KXX73536.1 - 0.065 13.3 0.5 0.54 10.3 0.1 2.0 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ZZ PF00569.17 KXX73537.1 - 4.1e-11 42.5 6.7 6.9e-11 41.8 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KXX73537.1 - 3.8e-09 35.4 5.5 5.7e-05 22.4 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KXX73537.1 - 2.1e-07 31.3 8.8 4.5e-05 23.8 0.4 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KXX73537.1 - 3e-05 23.6 10.8 0.00012 21.7 0.8 3.4 3 0 0 3 3 3 2 EF-hand domain C1_2 PF03107.16 KXX73537.1 - 0.0046 17.3 5.7 0.0081 16.5 5.7 1.4 1 0 0 1 1 1 1 C1 domain EF-hand_8 PF13833.6 KXX73537.1 - 0.035 14.0 6.2 0.8 9.6 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair Dockerin_1 PF00404.18 KXX73537.1 - 0.039 14.2 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_4 PF12763.7 KXX73537.1 - 0.18 11.7 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KXX73537.1 - 3.6 7.2 6.5 1.5 8.5 0.2 2.9 2 0 0 2 2 2 0 EF hand CAP_N PF01213.19 KXX73538.1 - 8.9 5.7 11.1 0.2 11.1 2.6 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Vps53_N PF04100.12 KXX73539.1 - 5.9e-102 341.5 0.3 9.7e-102 340.8 0.3 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2451 PF10474.9 KXX73539.1 - 3.5e-05 23.7 0.3 7.6e-05 22.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KXX73539.1 - 9.4e-05 21.8 3.1 0.00018 20.9 3.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KXX73539.1 - 0.0013 17.4 2.0 0.0022 16.6 2.0 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 RINT1_TIP1 PF04437.13 KXX73539.1 - 0.0025 16.8 0.5 0.71 8.7 0.0 2.6 3 0 0 3 3 3 2 RINT-1 / TIP-1 family VPS53_C PF16854.5 KXX73539.1 - 0.0062 16.4 0.0 0.1 12.5 0.0 2.6 2 1 1 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Spc7 PF08317.11 KXX73539.1 - 0.017 14.0 1.0 0.034 13.0 1.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3510 PF12022.8 KXX73539.1 - 0.15 12.4 1.0 1.3 9.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) APG6_N PF17675.1 KXX73539.1 - 0.38 11.3 2.3 0.88 10.1 1.4 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region tRNA-synt_1b PF00579.25 KXX73540.1 - 8e-80 268.3 0.0 1.1e-79 267.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KXX73540.1 - 1.5e-47 160.3 0.0 5.1e-47 158.6 0.0 2.0 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain NPR2 PF06218.11 KXX73541.1 - 1e-125 420.0 0.0 1.3e-125 419.7 0.0 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Ribosomal_60s PF00428.19 KXX73541.1 - 0.34 11.5 1.5 0.78 10.4 1.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein NUDIX PF00293.28 KXX73543.1 - 0.0015 18.6 0.0 0.0037 17.3 0.0 1.7 2 1 0 2 2 2 1 NUDIX domain NAD_binding_8 PF13450.6 KXX73546.1 - 5.4e-10 39.4 0.0 1.7e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXX73546.1 - 2.1e-07 29.7 0.1 2.9e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Thi4 PF01946.17 KXX73546.1 - 1.1e-05 24.8 0.0 6.8e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXX73546.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX73546.1 - 0.00047 19.5 0.1 0.019 14.2 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX73546.1 - 0.0031 16.8 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX73546.1 - 0.0049 16.0 0.1 0.035 13.2 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 KXX73546.1 - 0.016 15.7 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXX73546.1 - 0.019 14.3 0.0 0.12 11.7 0.0 2.1 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXX73546.1 - 0.053 13.5 0.0 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXX73546.1 - 0.076 12.1 0.0 6.5 5.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SnoaL_4 PF13577.6 KXX73547.1 - 2.2e-49 166.8 5.3 6.3e-21 74.8 0.6 3.7 4 0 0 4 4 4 3 SnoaL-like domain Big_3_5 PF16640.5 KXX73547.1 - 0.0011 19.1 3.0 0.0011 19.1 0.3 2.5 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) Thioredoxin PF00085.20 KXX73547.1 - 0.2 11.7 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Glyco_hydro_31 PF01055.26 KXX73549.1 - 6.9e-104 348.5 2.7 1e-103 347.9 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXX73549.1 - 1.2e-07 32.0 0.9 6.9e-07 29.5 0.7 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXX73549.1 - 7e-06 26.2 0.5 0.00018 21.7 0.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF5110) AAA PF00004.29 KXX73550.1 - 5.8e-07 30.0 0.0 4.9e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PDZ_6 PF17820.1 KXX73551.1 - 0.0012 18.6 0.3 0.0029 17.4 0.3 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_M61 PF05299.12 KXX73551.1 - 0.023 15.1 1.9 0.087 13.2 1.9 1.9 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M1 PF01433.20 KXX73551.1 - 0.068 12.7 0.3 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 Peptidase family M1 domain Lipase_GDSL_2 PF13472.6 KXX73552.1 - 7.1e-12 46.1 2.2 2.6e-09 37.7 0.0 3.0 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family fn3 PF00041.21 KXX73552.1 - 2.6e-10 40.5 0.1 8.1e-05 22.9 0.0 3.9 3 1 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL PF00657.22 KXX73552.1 - 0.0012 18.8 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SAPS PF04499.15 KXX73553.1 - 1.5e-189 630.9 0.0 7.2e-189 628.6 0.0 2.2 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein adh_short PF00106.25 KXX73554.1 - 2.4e-24 85.9 0.1 3.7e-18 65.7 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73554.1 - 1.8e-13 50.6 0.1 1.8e-09 37.5 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73554.1 - 9.2e-10 38.7 0.4 8.4e-09 35.6 0.2 2.1 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KXX73554.1 - 0.0058 16.9 0.1 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXX73554.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 KXX73554.1 - 0.041 13.8 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.15 KXX73554.1 - 0.05 12.7 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_3 PF07859.13 KXX73555.1 - 1.3e-28 100.4 0.0 2.2e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXX73555.1 - 0.0018 17.3 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 KXX73555.1 - 0.005 17.0 0.0 0.0076 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 KXX73555.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 KXX73556.1 - 3.6e-06 26.2 20.0 2.4e-05 23.4 6.4 2.5 2 0 0 2 2 2 2 Major Facilitator Superfamily SET PF00856.28 KXX73558.1 - 3.4e-06 27.5 0.0 7.9e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 SET domain Peroxidase_2 PF01328.17 KXX73559.1 - 2.2e-35 122.9 0.1 2.7e-35 122.6 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.8 KXX73560.1 - 7.3e-06 25.0 1.1 1.2e-05 24.4 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.14 KXX73561.1 - 8e-56 189.2 0.0 9.1e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Mg_trans_NIPA PF05653.14 KXX73562.1 - 1.5e-90 303.3 25.6 2.1e-90 302.9 25.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXX73562.1 - 4.9e-06 26.7 7.3 4.9e-06 26.7 7.3 3.1 3 0 0 3 3 3 1 EamA-like transporter family Ndc1_Nup PF09531.10 KXX73562.1 - 0.0057 15.4 1.9 0.011 14.4 1.9 1.6 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF5362 PF17319.2 KXX73562.1 - 0.71 9.8 0.0 0.71 9.8 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5362) ST7 PF04184.12 KXX73562.1 - 1.3 7.4 4.2 2 6.8 4.2 1.2 1 0 0 1 1 1 0 ST7 protein Ank_2 PF12796.7 KXX73563.1 - 1.2e-18 67.5 1.2 3.7e-07 30.6 0.0 5.5 4 2 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX73563.1 - 9.8e-15 53.2 4.6 0.018 15.5 0.0 7.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KXX73563.1 - 1.1e-14 54.5 5.2 0.0002 21.8 0.0 5.3 4 2 1 5 5 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX73563.1 - 1.6e-14 53.8 4.3 0.00039 20.6 0.2 5.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXX73563.1 - 1.3e-12 47.6 6.4 0.0021 18.4 0.3 6.4 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.12 KXX73563.1 - 1.5e-11 44.5 0.0 8.7e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX73563.1 - 1e-05 26.0 0.0 4.2e-05 24.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX73563.1 - 7.5e-05 23.0 0.0 0.00022 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain HTH_IclR PF09339.10 KXX73563.1 - 0.024 14.4 0.8 0.18 11.6 0.0 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain Helo_like_N PF17111.5 KXX73563.1 - 0.044 13.1 0.4 0.1 12.0 0.4 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins AAA_14 PF13173.6 KXX73563.1 - 0.08 13.0 0.0 0.25 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KXX73563.1 - 0.1 11.9 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Torsin PF06309.11 KXX73563.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin SesA PF17107.5 KXX73563.1 - 0.21 11.8 0.5 1.5 9.1 0.2 2.5 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Myb_DNA-binding PF00249.31 KXX73564.1 - 2.4e-09 37.3 0.0 7e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KXX73564.1 - 2.6e-07 30.9 0.0 8.7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.17 KXX73564.1 - 0.00041 20.1 4.1 0.00077 19.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SHOCT PF09851.9 KXX73564.1 - 0.027 14.2 0.6 0.1 12.4 0.6 2.1 1 0 0 1 1 1 0 Short C-terminal domain adh_short PF00106.25 KXX73565.1 - 3.8e-18 65.6 0.0 6.4e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73565.1 - 2.1e-13 50.4 0.0 8e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73565.1 - 0.00031 20.7 0.0 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXX73565.1 - 0.00051 19.6 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX73565.1 - 0.0011 18.9 0.2 0.024 14.5 0.2 2.4 1 1 0 1 1 1 1 NAD(P)H-binding Mucin PF01456.17 KXX73566.1 - 0.17 11.8 21.5 0.25 11.3 21.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FeS_assembly_P PF01883.19 KXX73567.1 - 1.9e-08 34.4 0.0 7e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 KXX73568.1 - 4.3e-46 156.9 0.0 6.3e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KXX73568.1 - 7e-37 126.7 8.1 1.3e-36 125.8 8.1 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KXX73568.1 - 8.4e-25 86.9 0.0 2.6e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KXX73568.1 - 1.8e-18 66.3 0.0 5.5e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXX73568.1 - 5.1e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXX73568.1 - 1e-06 28.7 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXX73568.1 - 6.6e-06 26.2 0.1 1.2e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXX73568.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Ras family Thiolase_N PF00108.23 KXX73569.1 - 3.8e-88 295.2 1.7 6.4e-88 294.5 1.7 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX73569.1 - 6.5e-46 155.0 0.5 1.5e-45 153.8 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXX73569.1 - 0.00064 19.4 0.8 0.0016 18.1 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXX73569.1 - 0.42 10.5 4.8 2.1 8.3 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.32 KXX73570.1 - 2.8e-10 40.6 0.5 0.18 12.7 0.0 5.3 4 1 1 5 5 5 3 WD domain, G-beta repeat Sel1 PF08238.12 KXX73571.1 - 3.4e-43 145.1 42.9 4.1e-05 24.1 0.1 12.8 12 2 1 13 13 13 10 Sel1 repeat TPR_6 PF13174.6 KXX73571.1 - 0.00011 22.6 21.0 0.2 12.3 0.3 8.7 8 1 0 8 8 8 2 Tetratricopeptide repeat DUF2681 PF10883.8 KXX73571.1 - 0.0056 17.1 3.5 0.013 15.9 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) OPA3 PF07047.12 KXX73571.1 - 0.022 14.5 1.1 0.046 13.5 1.1 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) GRP PF07172.11 KXX73571.1 - 0.027 15.1 0.0 0.17 12.6 0.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family DUF1003 PF06210.11 KXX73571.1 - 0.21 11.7 0.8 0.47 10.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) FHIPEP PF00771.20 KXX73571.1 - 0.27 9.7 0.4 0.39 9.1 0.4 1.1 1 0 0 1 1 1 0 FHIPEP family Fer2_3 PF13085.6 KXX73573.1 - 1.5e-33 115.1 0.0 2.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KXX73573.1 - 1.4e-08 35.1 6.0 1.4e-08 35.1 6.0 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXX73573.1 - 3e-07 30.4 3.4 3e-07 30.4 3.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXX73573.1 - 3.3e-07 30.7 8.3 3.3e-07 30.7 8.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KXX73573.1 - 0.0041 17.0 0.2 0.0041 17.0 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 KXX73573.1 - 0.017 15.3 0.4 0.55 10.4 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXX73573.1 - 0.017 15.7 5.7 0.017 15.7 5.7 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 KXX73573.1 - 0.12 12.2 0.4 0.2 11.5 0.4 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DNA_pol3_tau_4 PF12168.8 KXX73573.1 - 0.26 11.9 1.6 0.61 10.7 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_9 PF13187.6 KXX73573.1 - 0.39 10.9 10.8 2.6 8.3 9.1 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Hist_deacetyl PF00850.19 KXX73575.1 - 3.9e-80 269.6 0.0 5.2e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RCC1 PF00415.18 KXX73576.1 - 1.7e-23 83.0 0.1 3.8e-08 33.8 0.2 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KXX73576.1 - 8.7e-11 42.1 0.1 1.9e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) BTB PF00651.31 KXX73576.1 - 1.5e-08 34.9 0.0 3.1e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain RCC1_2 PF13540.6 KXX73576.1 - 1.2e-07 31.4 6.1 1.8e-06 27.6 0.5 4.1 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KXX73576.1 - 2.2e-06 28.2 0.1 7.3e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX73576.1 - 2.2e-05 24.5 0.1 0.21 12.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXX73576.1 - 0.054 13.8 0.0 0.32 11.4 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ATG13 PF10033.9 KXX73577.1 - 9.1e-76 254.7 0.0 1.3e-75 254.2 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 UDPGP PF01704.18 KXX73578.1 - 2.5e-191 635.8 0.0 2.9e-191 635.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DAO_C PF16901.5 KXX73578.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase ING PF12998.7 KXX73579.1 - 2.7e-23 82.4 6.3 4.1e-23 81.9 6.3 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXX73579.1 - 0.00034 20.4 8.8 0.00057 19.7 8.8 1.3 1 0 0 1 1 1 1 PHD-finger DUF1704 PF08014.11 KXX73579.1 - 0.03 13.3 0.2 0.044 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) zf-HC5HC2H PF13771.6 KXX73579.1 - 0.033 14.4 0.2 0.068 13.4 0.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PP1_bind PF15276.6 KXX73579.1 - 0.12 12.7 0.8 0.51 10.7 0.8 2.1 1 0 0 1 1 1 0 Protein phosphatase 1 binding Tmemb_cc2 PF10267.9 KXX73579.1 - 0.83 8.7 5.3 0.77 8.8 4.1 1.7 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DivIC PF04977.15 KXX73579.1 - 2.1 8.2 4.7 22 4.9 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator Mito_carr PF00153.27 KXX73580.1 - 6.1e-65 215.2 3.5 5.8e-24 83.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pept_tRNA_hydro PF01195.19 KXX73580.1 - 0.05 13.6 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase Tim17 PF02466.19 KXX73580.1 - 0.14 12.6 4.0 0.21 12.0 1.6 2.7 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family zf-C3HC4_3 PF13920.6 KXX73581.1 - 0.002 17.9 11.0 0.0031 17.3 11.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXX73581.1 - 0.33 10.9 6.1 0.54 10.2 6.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KXX73581.1 - 8.1 6.5 12.6 13 5.8 12.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain FA_hydroxylase PF04116.13 KXX73582.1 - 2.9e-21 76.2 14.3 2.9e-21 76.2 14.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Dor1 PF04124.12 KXX73582.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family DUF4519 PF15012.6 KXX73582.1 - 0.24 11.6 1.3 0.63 10.2 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) SesA PF17107.5 KXX73584.1 - 1.9e-23 83.0 0.0 8e-23 80.9 0.1 2.0 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 KXX73584.1 - 5.8e-19 68.0 15.8 8.5e-19 67.4 15.8 1.3 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases DAGK_cat PF00781.24 KXX73584.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.9 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain NACHT_sigma PF17106.5 KXX73585.1 - 0.00013 22.0 1.3 0.00027 21.0 1.3 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases PPR_2 PF13041.6 KXX73586.1 - 1.1e-30 105.5 0.0 3e-08 33.7 0.0 7.3 6 1 1 7 7 7 6 PPR repeat family PPR_3 PF13812.6 KXX73586.1 - 3.2e-19 68.8 0.0 1.8e-06 27.9 0.0 5.7 4 2 3 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 KXX73586.1 - 2.9e-17 61.6 0.0 0.02 15.1 0.0 6.4 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.7 KXX73586.1 - 1.6e-11 43.7 0.1 0.052 13.3 0.0 5.5 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 KXX73586.1 - 4.3e-08 32.8 0.0 0.0011 18.4 0.0 3.4 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP CCDC24 PF15669.5 KXX73586.1 - 0.029 14.3 0.0 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Septin PF00735.18 KXX73587.1 - 2.4e-16 59.9 0.0 1.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 KXX73587.1 - 6.2e-05 23.1 0.0 0.00045 20.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX73587.1 - 0.00052 20.0 0.1 0.019 14.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 KXX73587.1 - 0.0034 17.8 0.0 0.0081 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KXX73587.1 - 0.0059 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KXX73587.1 - 0.0084 16.5 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 KXX73587.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 KXX73587.1 - 0.032 14.0 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 KXX73587.1 - 0.038 13.2 0.3 0.097 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXX73587.1 - 0.038 13.5 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KXX73587.1 - 0.04 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXX73587.1 - 0.047 14.2 0.0 0.099 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 KXX73587.1 - 0.087 12.0 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KXX73587.1 - 0.088 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXX73587.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX73587.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXX73587.1 - 0.15 12.4 0.1 0.26 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXX73587.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXX73587.1 - 0.17 11.1 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Gtr1_RagA PF04670.12 KXX73587.1 - 0.22 10.8 0.0 12 5.1 0.0 2.4 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 KXX73587.1 - 0.25 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 NTPase DUF3435 PF11917.8 KXX73588.1 - 3.1e-76 257.0 0.1 3.9e-76 256.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) WD40 PF00400.32 KXX73590.1 - 1e-21 76.8 0.9 1.1e-10 41.9 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX73590.1 - 0.0013 19.0 0.0 0.027 14.8 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXX73592.1 - 1.8e-13 50.8 1.4 3.8e-07 30.2 0.1 2.5 1 1 1 2 2 2 2 NACHT domain Mlp PF03304.13 KXX73592.1 - 0.0044 17.3 0.2 0.011 16.0 0.1 1.7 2 0 0 2 2 2 1 Mlp lipoprotein family AAA_19 PF13245.6 KXX73592.1 - 0.15 12.4 0.1 0.57 10.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain Cwf_Cwc_15 PF04889.12 KXX73593.1 - 4.6 6.9 27.0 0.12 12.1 6.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRM_1 PF00076.22 KXX73594.1 - 4.7e-10 39.2 0.1 8.6e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXX73594.1 - 1.3e-05 25.0 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXX73594.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif RP-C PF03428.13 KXX73594.1 - 0.056 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain p450 PF00067.22 KXX73595.1 - 4.7e-47 160.8 0.0 6.5e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_1 PF00036.32 KXX73596.1 - 3.8e-21 73.0 6.3 3.6e-07 29.2 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KXX73596.1 - 7.6e-20 71.1 1.9 2.2e-12 47.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXX73596.1 - 8.3e-19 65.9 4.8 8e-07 28.5 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KXX73596.1 - 1.6e-14 53.5 4.9 5.6e-09 35.7 0.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KXX73596.1 - 1.8e-11 43.0 8.4 7.6e-05 22.0 0.4 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KXX73596.1 - 3e-05 24.3 0.0 0.00089 19.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 KXX73596.1 - 0.0057 16.6 0.0 0.92 9.4 0.0 2.1 2 0 0 2 2 2 2 Caleosin related protein EF-hand_4 PF12763.7 KXX73596.1 - 0.028 14.4 0.1 0.73 9.8 0.0 2.3 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 KXX73596.1 - 0.03 14.4 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 KXX73596.1 - 0.046 14.1 0.0 1.4 9.2 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2958 PF11171.8 KXX73596.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) DUF2046 PF09755.9 KXX73597.1 - 0.0031 16.8 0.6 0.016 14.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Nnf1 PF03980.14 KXX73597.1 - 0.009 16.4 2.0 0.058 13.8 1.7 2.2 2 0 0 2 2 2 1 Nnf1 KIAA1430 PF13879.6 KXX73597.1 - 0.03 15.1 0.1 0.084 13.6 0.1 1.8 1 0 0 1 1 1 0 KIAA1430 homologue OrfB_IS605 PF01385.19 KXX73597.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Probable transposase DivIC PF04977.15 KXX73597.1 - 1.8 8.4 6.7 0.093 12.5 1.0 1.7 2 0 0 2 2 2 0 Septum formation initiator BUD22 PF09073.10 KXX73600.1 - 9.5e-100 335.0 41.6 3.1e-61 208.1 20.5 2.0 1 1 1 2 2 2 2 BUD22 ABC2_membrane PF01061.24 KXX73602.1 - 5.7e-76 254.6 52.8 8.1e-39 133.2 18.7 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXX73602.1 - 1.1e-38 132.8 0.0 3.4e-18 66.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXX73602.1 - 9.7e-24 83.1 6.5 2e-21 75.7 0.0 4.0 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 KXX73602.1 - 4.9e-19 68.7 0.0 2.4e-18 66.5 0.0 2.3 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXX73602.1 - 4.7e-07 30.4 0.6 0.016 15.6 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KXX73602.1 - 9.1e-07 29.1 0.1 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KXX73602.1 - 3.5e-06 27.0 0.0 0.073 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXX73602.1 - 3.1e-05 23.2 33.2 0.00027 20.2 10.2 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KXX73602.1 - 6.4e-05 23.5 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXX73602.1 - 0.00013 21.6 0.4 0.0095 15.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXX73602.1 - 0.00036 20.5 0.1 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_17 PF13207.6 KXX73602.1 - 0.00039 20.8 3.5 0.016 15.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KXX73602.1 - 0.0006 20.1 0.1 0.59 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KXX73602.1 - 0.00082 19.6 0.1 0.076 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXX73602.1 - 0.00087 18.9 0.1 0.019 14.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXX73602.1 - 0.0043 16.5 0.0 0.77 9.2 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 KXX73602.1 - 0.0045 16.6 2.8 0.26 10.8 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KXX73602.1 - 0.0092 16.3 0.6 0.43 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXX73602.1 - 0.0095 15.9 1.3 3 7.8 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 KXX73602.1 - 0.01 15.6 0.5 2 8.1 0.3 2.6 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KXX73602.1 - 0.026 13.9 0.1 2.6 7.3 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KXX73602.1 - 0.074 12.8 0.1 15 5.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXX73602.1 - 0.11 13.0 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 KXX73602.1 - 0.13 11.9 0.0 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KXX73602.1 - 0.14 12.5 0.2 17 5.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXX73602.1 - 0.28 11.2 1.9 6 6.9 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 KXX73603.1 - 2.5e-30 105.5 0.1 5.9e-15 55.5 0.1 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX73603.1 - 9.6e-21 74.2 0.0 3.2e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX73603.1 - 1.5e-05 25.0 0.0 6.4e-05 23.0 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AF-4 PF05110.13 KXX73603.1 - 0.0029 15.8 16.9 0.0029 15.8 16.9 2.1 2 0 0 2 2 2 1 AF-4 proto-oncoprotein HSP70 PF00012.20 KXX73604.1 - 5.3e-13 48.0 0.0 1.1e-10 40.4 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.20 KXX73604.1 - 0.0034 16.9 1.1 0.0054 16.3 0.0 1.8 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family NTP_transf_7 PF07984.12 KXX73604.1 - 0.037 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase Peptidase_M22 PF00814.25 KXX73604.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 1 0 1 1 1 0 Glycoprotease family Tropomyosin PF00261.20 KXX73605.1 - 0.00047 19.6 4.5 0.0006 19.2 2.3 2.0 2 0 0 2 2 2 1 Tropomyosin Csm1_N PF18504.1 KXX73605.1 - 0.6 10.5 3.9 36 4.8 1.6 3.1 3 1 0 3 3 3 0 Csm1 N-terminal domain SlyX PF04102.12 KXX73606.1 - 0.00063 20.3 0.3 0.0012 19.4 0.3 1.5 1 0 0 1 1 1 1 SlyX ATG16 PF08614.11 KXX73606.1 - 0.0023 18.2 1.5 0.0044 17.3 0.0 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF16 PF01519.16 KXX73606.1 - 0.0037 17.7 0.9 0.0056 17.1 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 Filament PF00038.21 KXX73606.1 - 0.0047 16.6 0.6 0.0062 16.2 0.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein TACC_C PF05010.14 KXX73606.1 - 0.011 15.5 0.6 0.016 15.0 0.6 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4407 PF14362.6 KXX73606.1 - 0.013 14.8 0.6 0.018 14.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 KXX73606.1 - 0.016 15.1 0.2 0.026 14.4 0.2 1.3 1 0 0 1 1 1 0 Spc19 BST2 PF16716.5 KXX73606.1 - 0.022 15.4 2.2 0.038 14.6 2.2 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 HAP1_N PF04849.13 KXX73606.1 - 0.031 13.5 1.4 0.043 13.0 1.4 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Spc7 PF08317.11 KXX73606.1 - 0.04 12.8 1.2 0.053 12.4 1.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 KXX73606.1 - 0.075 11.7 1.1 0.098 11.3 1.1 1.0 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 KXX73606.1 - 0.086 13.3 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cob_adeno_trans PF01923.18 KXX73606.1 - 0.091 12.9 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF1729 PF08354.10 KXX73606.1 - 0.16 10.8 0.2 0.23 10.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) DivIC PF04977.15 KXX73606.1 - 0.17 11.7 4.4 0.47 10.2 1.2 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF3987 PF13148.6 KXX73606.1 - 0.17 10.8 1.3 0.25 10.3 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TMF_DNA_bd PF12329.8 KXX73606.1 - 0.18 11.8 4.0 0.32 11.0 4.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 KXX73606.1 - 0.25 11.6 3.4 0.38 11.0 3.4 1.2 1 0 0 1 1 1 0 Haemolysin XhlA Csm1_N PF18504.1 KXX73606.1 - 0.28 11.6 3.3 0.48 10.8 3.3 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain LegC3_N PF18654.1 KXX73606.1 - 0.28 10.4 4.4 0.16 11.1 2.0 1.6 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain Fib_alpha PF08702.10 KXX73606.1 - 0.37 11.0 2.2 0.57 10.4 2.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tup_N PF08581.10 KXX73606.1 - 0.38 11.1 4.3 11 6.4 0.2 2.2 1 1 1 2 2 2 0 Tup N-terminal FlaC_arch PF05377.11 KXX73606.1 - 0.43 11.0 2.8 0.77 10.2 2.8 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HSP70 PF00012.20 KXX73607.1 - 1.7e-55 188.3 21.0 3.8e-54 183.9 8.9 3.7 2 1 0 2 2 2 1 Hsp70 protein Rx_N PF18052.1 KXX73607.1 - 4.3 7.7 10.9 20 5.5 0.2 3.8 2 1 1 3 3 3 0 Rx N-terminal domain IBR PF01485.21 KXX73608.1 - 2.5e-13 50.0 18.7 2.6e-11 43.6 2.5 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 KXX73608.1 - 0.026 14.2 2.2 2.1 8.2 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF2052 PF09747.9 KXX73608.1 - 0.043 13.9 15.1 0.084 13.0 15.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CAF-1_p150 PF11600.8 KXX73608.1 - 0.23 11.1 28.5 0.44 10.2 28.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SRP-alpha_N PF04086.13 KXX73608.1 - 1.2 9.1 14.9 0.068 13.1 9.2 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF3090 PF11290.8 KXX73608.1 - 1.2 8.9 8.5 0.98 9.2 6.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3090) zf-ribbon_3 PF13248.6 KXX73608.1 - 1.4 8.5 5.9 13 5.4 2.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Med19 PF10278.9 KXX73608.1 - 1.6 8.7 10.6 2.8 7.8 10.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 zf-C3HC4_3 PF13920.6 KXX73608.1 - 1.9 8.4 17.3 0.2 11.5 4.3 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) AAA_11 PF13086.6 KXX73608.1 - 2.4 7.9 8.7 4.1 7.1 8.7 1.3 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 KXX73608.1 - 3 6.0 13.3 4.4 5.5 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 KXX73608.1 - 4 5.8 8.3 6.4 5.1 8.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TERB2 PF15101.6 KXX73608.1 - 5.4 7.0 7.2 11 6.0 7.2 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PA26 PF04636.13 KXX73608.1 - 9.8 5.0 7.4 14 4.4 7.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Bromodomain PF00439.25 KXX73609.1 - 1.2e-08 34.9 0.0 7.5e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Bromodomain SH3_1 PF00018.28 KXX73610.1 - 4.1e-37 125.6 5.4 6.6e-13 48.1 0.4 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KXX73610.1 - 3.6e-35 119.6 7.4 1.2e-12 47.5 0.3 4.3 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 KXX73610.1 - 3.4e-34 116.5 0.0 6e-34 115.7 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KXX73610.1 - 2.5e-24 84.7 0.2 4.3e-08 32.7 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.11 KXX73610.1 - 4.9e-05 23.5 5.8 0.4 11.0 0.9 3.4 3 0 0 3 3 3 3 Bacterial SH3 domain SAM_4 PF18017.1 KXX73610.1 - 0.00027 20.9 0.0 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KXX73610.1 - 0.00054 20.0 0.3 2.7 8.1 0.0 3.5 3 0 0 3 3 3 2 SH3 domain DUF1720 PF08226.11 KXX73610.1 - 0.011 16.1 27.3 0.011 16.1 27.3 7.5 2 1 4 6 6 6 0 Domain of unknown function (DUF1720) Polysacc_deac_1 PF01522.21 KXX73611.1 - 1.6e-20 73.3 0.0 2.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KXX73611.1 - 0.098 11.8 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase DUF1877 PF08974.10 KXX73611.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) TRAM_LAG1_CLN8 PF03798.16 KXX73612.1 - 6.8e-53 179.4 14.1 1.1e-52 178.7 14.1 1.3 1 0 0 1 1 1 1 TLC domain DUF4360 PF14273.6 KXX73613.1 - 0.00033 20.6 0.7 0.00078 19.4 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4360) A_deaminase PF00962.22 KXX73614.1 - 8.8e-120 399.9 0.1 1.2e-119 399.5 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 KXX73614.1 - 3.4e-97 325.3 10.6 5.4e-97 324.6 10.6 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KXX73614.1 - 0.008 15.4 9.2 0.019 14.2 9.2 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter Tetraspanin PF00335.20 KXX73614.1 - 0.56 9.9 4.7 0.063 13.0 0.2 1.6 2 0 0 2 2 2 0 Tetraspanin family ABC_membrane PF00664.23 KXX73615.1 - 2.2e-22 80.0 2.5 2.2e-22 80.0 2.5 2.7 3 1 0 3 3 3 1 ABC transporter transmembrane region Tmemb_cc2 PF10267.9 KXX73615.1 - 1.4 8.0 2.6 1.9 7.5 2.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RTA1 PF04479.13 KXX73616.1 - 1.9e-66 223.6 8.9 1.9e-66 223.6 8.9 2.0 1 1 1 2 2 2 2 RTA1 like protein DUF485 PF04341.12 KXX73616.1 - 0.018 15.0 0.5 0.018 15.0 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 TPR_12 PF13424.6 KXX73617.1 - 5.1e-43 145.2 16.7 2.5e-15 56.5 1.7 4.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXX73617.1 - 1.1e-35 120.5 14.6 8e-13 47.8 0.0 5.8 6 1 0 6 6 6 4 Tetratricopeptide repeat Clr5 PF14420.6 KXX73617.1 - 3.1e-15 56.1 0.0 8e-15 54.8 0.0 1.7 2 0 0 2 2 1 1 Clr5 domain TPR_7 PF13176.6 KXX73617.1 - 2.3e-06 27.2 1.6 0.013 15.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX73617.1 - 5.3e-06 26.0 0.8 5.3e-06 26.0 0.8 1.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 KXX73617.1 - 8.1e-06 25.4 3.1 0.076 12.9 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX73617.1 - 0.00053 20.6 0.9 0.49 11.1 0.1 4.3 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXX73617.1 - 0.0007 19.8 1.3 1.4 9.5 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXX73617.1 - 0.0011 18.9 7.3 0.27 11.4 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX73617.1 - 0.0027 17.8 0.2 0.51 10.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 KXX73617.1 - 0.0079 16.2 3.5 2.8 8.0 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXX73617.1 - 0.0091 16.5 5.7 0.14 12.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX73617.1 - 0.012 16.1 3.0 0.055 14.0 0.8 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX73617.1 - 0.095 12.9 1.0 4.4 7.6 0.0 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 kleA_kleC PF17383.2 KXX73617.1 - 0.24 11.8 1.8 22 5.4 0.1 2.7 3 0 0 3 3 2 0 Uncharacterized KorC regulated protein A VIT PF08487.10 KXX73618.1 - 2.6e-36 124.2 0.0 6.3e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KXX73618.1 - 6.4e-27 94.4 0.0 1.5e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXX73618.1 - 1.4e-15 56.9 0.0 4.7e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KXX73618.1 - 1e-10 42.1 0.1 2e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXX73618.1 - 1.2e-08 35.5 0.0 3.1e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXX73618.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF2201 PF09967.9 KXX73618.1 - 0.066 13.4 0.0 0.37 11.0 0.0 2.1 1 1 0 1 1 1 0 VWA-like domain (DUF2201) DM PF00751.18 KXX73620.1 - 5.6 6.9 7.3 0.45 10.5 1.5 2.0 2 0 0 2 2 2 0 DM DNA binding domain HET PF06985.11 KXX73622.1 - 3.4e-07 30.7 0.0 3.1e-05 24.4 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Leu_leader PF08054.11 KXX73622.1 - 1.9 8.2 3.6 24 4.6 0.1 2.6 2 0 0 2 2 2 0 Leucine operon leader peptide FRG PF08867.11 KXX73623.1 - 0.18 12.8 0.5 0.41 11.6 0.5 1.6 1 0 0 1 1 1 0 FRG domain zf-CHCC PF10276.9 KXX73624.1 - 7.8e-17 61.0 1.1 1.2e-16 60.4 1.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain MPP6 PF10175.9 KXX73625.1 - 6.6e-05 23.4 0.2 6.6e-05 23.4 0.2 2.7 2 1 0 2 2 2 1 M-phase phosphoprotein 6 zf-CCHC PF00098.23 KXX73625.1 - 0.0019 18.2 2.5 0.0031 17.5 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXX73625.1 - 0.12 12.2 4.3 0.22 11.4 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M16_M PF16187.5 KXX73626.1 - 3.4e-93 312.0 0.5 5.7e-93 311.2 0.0 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXX73626.1 - 8.2e-34 117.2 0.2 4e-18 66.1 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXX73626.1 - 7.7e-29 100.6 1.4 2.5e-28 98.9 0.1 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HEAT PF02985.22 KXX73627.1 - 3.5e-39 129.5 9.9 0.056 13.7 0.0 12.9 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.6 KXX73627.1 - 3e-31 107.6 5.2 7.8e-09 35.8 0.0 8.2 4 2 4 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.7 KXX73627.1 - 2e-11 44.4 4.8 0.071 13.7 0.1 7.5 5 2 4 9 9 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXX73627.1 - 1.5e-10 41.3 14.2 0.047 14.2 0.0 8.9 9 3 2 11 11 10 2 HEAT-like repeat Cnd1 PF12717.7 KXX73627.1 - 1.9e-10 41.0 14.0 6.8e-06 26.2 0.3 6.0 4 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXX73627.1 - 1.8e-08 33.4 4.7 0.00036 19.2 0.2 4.2 3 1 2 5 5 5 3 Adaptin N terminal region RTP1_C1 PF10363.9 KXX73627.1 - 2.7e-05 24.3 4.7 0.018 15.2 0.1 4.7 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KXX73627.1 - 0.00011 21.8 2.2 0.86 9.1 0.1 4.7 3 3 1 4 4 4 2 CLASP N terminal Arm PF00514.23 KXX73627.1 - 0.0017 18.3 0.5 2.3 8.4 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Ecm29 PF13001.7 KXX73627.1 - 0.023 13.4 1.7 2.4 6.7 0.0 3.4 4 0 0 4 4 4 0 Proteasome stabiliser IFRD PF05004.13 KXX73627.1 - 0.088 11.9 0.9 2.3 7.2 0.0 3.1 2 2 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Nop52 PF05997.12 KXX73627.1 - 0.12 12.2 0.0 0.75 9.6 0.0 2.4 1 1 0 1 1 1 0 Nucleolar protein,Nop52 API5 PF05918.11 KXX73627.1 - 0.79 8.5 5.1 0.48 9.2 0.2 3.0 4 1 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) CdvA PF18822.1 KXX73628.1 - 0.012 15.4 0.2 0.029 14.2 0.2 1.6 1 0 0 1 1 1 0 CdvA-like coiled-coil domain CDC45 PF02724.14 KXX73628.1 - 1.7 6.9 7.5 3.1 6.0 7.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_31 PF13847.6 KXX73629.1 - 3.4e-17 62.6 0.0 5.7e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX73629.1 - 3.4e-12 46.9 0.1 6.7e-10 39.6 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX73629.1 - 9.9e-08 32.5 0.0 4.6e-06 27.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX73629.1 - 2.6e-07 30.6 0.0 5.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX73629.1 - 7.2e-06 26.7 0.0 3.6e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXX73629.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KXX73629.1 - 5.1e-05 22.7 0.0 0.00026 20.4 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX73629.1 - 6.8e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KXX73629.1 - 0.00028 20.9 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXX73629.1 - 0.0033 16.8 0.0 0.94 8.7 0.1 2.1 1 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KXX73629.1 - 0.016 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KXX73629.1 - 0.047 13.8 0.0 0.084 13.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase AdoMet_MTase PF07757.13 KXX73629.1 - 0.063 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase GCD14 PF08704.10 KXX73629.1 - 0.17 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KXX73629.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 KXX73629.1 - 0.25 10.4 0.0 0.58 9.2 0.0 1.5 2 0 0 2 2 2 0 mRNA capping enzyme SEP PF08059.13 KXX73630.1 - 5.6e-23 81.3 0.0 1.2e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 KXX73630.1 - 5e-13 48.6 0.5 7.9e-13 48.0 0.5 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXX73630.1 - 8.2e-09 35.6 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 KXX73630.1 - 0.033 13.8 0.1 0.056 13.1 0.1 1.3 1 0 0 1 1 1 0 TAP C-terminal domain TOM13 PF08219.11 KXX73631.1 - 3.5e-34 116.6 0.1 4.5e-34 116.3 0.1 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 KXX73632.1 - 2.3e-17 63.4 1.1 2.3e-17 63.4 1.1 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein DUF5604 PF18300.1 KXX73632.1 - 0.036 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5604) DUF349 PF03993.12 KXX73632.1 - 3.8 7.9 6.7 3.1 8.2 2.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Pro_CA PF00484.19 KXX73633.1 - 0.0043 17.4 0.0 0.0063 16.8 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase MFS_1 PF07690.16 KXX73634.1 - 1.7e-41 142.4 43.2 3.8e-41 141.2 43.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX73634.1 - 4.7e-06 25.3 14.8 7.2e-06 24.7 14.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.7 KXX73635.1 - 9.4e-39 131.9 12.1 1.8e-06 28.4 0.0 10.8 8 3 3 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX73635.1 - 3.9e-22 78.3 13.8 1.1e-05 25.9 0.0 10.3 10 2 2 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73635.1 - 3.6e-20 69.9 14.8 0.05 14.2 0.0 14.4 15 1 1 16 16 16 4 Ankyrin repeat Ank PF00023.30 KXX73635.1 - 2.6e-13 49.7 25.0 0.073 13.6 1.1 12.2 13 1 1 14 14 14 4 Ankyrin repeat Ank_5 PF13857.6 KXX73635.1 - 8.2e-12 45.1 8.7 0.0048 17.2 0.0 7.4 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Nodulin-like PF06813.13 KXX73635.1 - 0.13 11.7 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Nodulin-like Zn_clus PF00172.18 KXX73636.1 - 5.7e-08 32.8 7.3 1e-07 32.0 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.20 KXX73637.1 - 4.9e-15 56.0 0.0 8.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Erythro_esteras PF05139.14 KXX73638.1 - 3.1e-131 438.3 3.3 3.7e-131 438.0 3.3 1.1 1 0 0 1 1 1 1 Erythromycin esterase Gtr1_RagA PF04670.12 KXX73639.1 - 2.2e-98 328.2 0.0 2.8e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXX73639.1 - 2.3e-09 37.5 0.0 4.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX73639.1 - 6.9e-09 35.4 0.1 1e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXX73639.1 - 1.4e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KXX73639.1 - 2.3e-07 30.9 0.0 4.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX73639.1 - 0.0009 19.2 1.3 0.037 13.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 KXX73639.1 - 0.0029 16.8 1.7 0.46 9.6 0.8 2.6 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 KXX73639.1 - 0.003 17.3 0.4 0.032 14.0 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KXX73639.1 - 0.0094 16.5 0.1 0.022 15.3 0.1 1.5 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 KXX73639.1 - 0.011 15.0 0.1 0.022 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KXX73639.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain LRR_8 PF13855.6 KXX73641.1 - 6.9e-33 112.2 47.5 6e-06 25.9 0.1 8.3 6 2 2 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 KXX73641.1 - 6e-28 96.5 46.0 4.4e-06 27.0 4.8 10.2 6 4 2 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXX73641.1 - 4.9e-10 38.6 33.7 6.8 7.7 1.8 13.0 12 1 0 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.6 KXX73641.1 - 4.5e-08 32.5 37.3 2.4 8.4 0.0 11.2 12 0 0 12 12 12 6 Leucine Rich repeat LRR_9 PF14580.6 KXX73641.1 - 6.2e-05 22.6 13.9 0.048 13.2 0.0 5.3 2 2 3 5 5 5 3 Leucine-rich repeat DPM3 PF08285.11 KXX73642.1 - 6.9e-34 115.9 0.5 7.7e-34 115.8 0.5 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pribosyltran PF00156.27 KXX73643.1 - 2.5e-07 30.4 0.0 3.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.9 KXX73644.1 - 8.6e-25 86.2 3.5 8.6e-25 86.2 3.5 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal CDC27 PF09507.10 KXX73644.1 - 0.00082 18.9 11.9 0.001 18.6 11.9 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Mitofilin PF09731.9 KXX73644.1 - 4.9 5.9 16.0 6.5 5.5 16.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DAHP_synth_1 PF00793.20 KXX73646.1 - 2.3e-105 351.4 0.1 2.9e-105 351.1 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Zn_clus PF00172.18 KXX73648.1 - 0.023 14.8 14.2 0.046 13.8 14.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KXX73649.1 - 0.0026 17.8 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold TctB PF07331.11 KXX73650.1 - 0.19 12.0 12.6 3 8.1 0.0 2.6 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family 7TMR-DISM_7TM PF07695.11 KXX73650.1 - 0.26 11.2 14.5 0.13 12.1 12.2 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling Apt1 PF10351.9 KXX73650.1 - 0.84 8.4 2.9 1.1 8.0 2.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Thiolase_N PF00108.23 KXX73651.1 - 9e-16 58.0 0.1 6e-15 55.3 0.0 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX73651.1 - 5.7e-10 38.9 1.3 1.1e-09 38.0 0.2 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXX73651.1 - 8.4e-06 25.6 0.8 0.00012 21.8 0.2 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KXX73651.1 - 0.0012 18.5 0.2 0.0048 16.5 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KXX73651.1 - 0.0075 15.0 0.6 0.18 10.5 0.2 2.5 3 0 0 3 3 3 1 Stage V sporulation protein AD (SpoVAD) MRP-S25 PF13741.6 KXX73652.1 - 4.7e-25 88.5 5.2 1.8e-22 80.0 5.2 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.6 KXX73653.1 - 4.5e-14 52.4 3.2 0.00011 22.3 0.1 5.4 5 2 1 6 6 6 4 PPR repeat family PPR PF01535.20 KXX73653.1 - 3.7e-12 45.6 13.0 0.0022 18.1 0.0 7.3 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.7 KXX73653.1 - 0.00019 21.0 0.2 6.2 6.6 0.0 4.4 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 KXX73653.1 - 0.00023 21.2 0.1 0.31 11.2 0.0 3.9 3 1 0 4 4 4 1 Pentatricopeptide repeat domain Ald_Xan_dh_C2 PF02738.18 KXX73654.1 - 1.6e-208 693.6 0.6 2.3e-208 693.2 0.6 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXX73654.1 - 1.4e-50 171.3 0.0 2.8e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KXX73654.1 - 4.9e-32 110.2 1.5 5.9e-31 106.7 0.0 3.0 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KXX73654.1 - 1.1e-30 106.2 0.0 2.8e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KXX73654.1 - 5.8e-30 103.1 0.1 1.2e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KXX73654.1 - 3.1e-08 33.4 2.0 4.5e-08 32.9 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KXX73654.1 - 0.062 13.3 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 DUF218 domain Aldedh PF00171.22 KXX73656.1 - 5.3e-140 467.0 0.0 6.2e-140 466.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXX73656.1 - 6.8e-05 22.1 0.2 0.00034 19.8 0.2 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) GH3 PF03321.13 KXX73656.1 - 0.2 10.5 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter RIO1 PF01163.22 KXX73657.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KXX73657.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain HET PF06985.11 KXX73658.1 - 1.1e-16 61.4 0.0 1.6e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Metallophos PF00149.28 KXX73659.1 - 1e-08 35.9 0.0 2.2e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX73659.1 - 4.7e-08 33.4 0.1 4.9e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain p450 PF00067.22 KXX73661.1 - 4.9e-51 173.9 0.1 5.8e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Herpes_U30 PF04523.13 KXX73661.1 - 0.06 11.2 0.2 0.073 11.0 0.2 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 zf-met PF12874.7 KXX73662.1 - 0.025 15.0 2.0 0.22 11.9 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KXX73662.1 - 0.053 14.0 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KXX73662.1 - 0.16 12.3 0.9 0.68 10.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Dehydrin PF00257.19 KXX73662.1 - 0.8 10.2 8.6 0.044 14.3 1.7 2.2 2 0 0 2 2 2 0 Dehydrin zf-BED PF02892.15 KXX73662.1 - 1.8 8.6 5.6 1.1 9.4 3.0 1.9 2 0 0 2 2 2 0 BED zinc finger GMC_oxred_N PF00732.19 KXX73664.1 - 3.8e-28 98.7 0.0 6.4e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX73664.1 - 7.8e-23 81.6 0.1 1.4e-22 80.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX73664.1 - 6.8e-09 35.3 0.1 0.00044 19.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXX73664.1 - 7e-05 23.0 2.6 0.00012 22.2 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX73664.1 - 0.00058 19.2 0.0 0.0016 17.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX73664.1 - 0.015 14.0 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KXX73664.1 - 0.016 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KXX73664.1 - 0.021 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXX73664.1 - 0.041 13.1 0.2 0.076 12.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXX73664.1 - 0.054 12.8 0.0 0.58 9.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXX73664.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pho88 PF10032.9 KXX73665.1 - 3.3e-80 267.6 0.0 3.8e-80 267.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Asp PF00026.23 KXX73666.1 - 8.6e-76 255.4 2.1 1.1e-75 255.1 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX73666.1 - 1.2e-13 51.7 1.9 3.1e-06 27.6 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXX73666.1 - 0.0058 17.3 0.2 0.25 12.0 0.0 3.1 2 2 0 2 2 2 1 Aspartyl protease CENP-S PF15630.6 KXX73666.1 - 0.24 11.8 0.0 0.66 10.4 0.0 1.7 2 0 0 2 2 2 0 CENP-S protein PTR2 PF00854.21 KXX73667.1 - 4.7e-44 150.8 1.7 6.7e-44 150.3 1.7 1.2 1 0 0 1 1 1 1 POT family XPA_C PF05181.12 KXX73668.1 - 2.3e-26 91.5 3.1 4.9e-26 90.4 3.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KXX73668.1 - 0.00076 19.5 5.1 0.00076 19.5 5.1 2.4 3 0 0 3 3 3 1 XPA protein N-terminal ArfGap PF01412.18 KXX73668.1 - 1.6 8.9 5.9 0.34 11.0 1.5 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Striatin PF08232.12 KXX73669.1 - 3.2e-41 141.5 4.7 3.2e-41 141.5 4.7 1.8 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KXX73669.1 - 1.2e-26 92.5 14.4 6.9e-05 23.5 0.1 7.3 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX73669.1 - 2.8e-07 30.7 0.1 0.6 10.4 0.0 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain CALCOCO1 PF07888.11 KXX73669.1 - 0.022 13.6 4.2 0.042 12.7 4.2 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADH_N_2 PF16884.5 KXX73669.1 - 0.034 14.0 0.0 0.25 11.3 0.0 2.2 1 1 1 2 2 2 0 N-terminal domain of oxidoreductase DUF3450 PF11932.8 KXX73669.1 - 0.062 12.6 2.2 0.12 11.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ge1_WD40 PF16529.5 KXX73669.1 - 0.085 11.8 0.0 0.45 9.4 0.0 2.1 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4482 PF14818.6 KXX73669.1 - 7.3 7.5 9.8 0.48 11.3 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) FAR1 PF03101.15 KXX73670.1 - 3e-05 24.6 0.1 7.3e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF1319 PF07028.11 KXX73670.1 - 0.0035 17.5 0.5 0.012 15.9 0.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) Clr5 PF14420.6 KXX73671.1 - 7e-08 32.6 2.0 1.5e-07 31.5 2.0 1.5 1 0 0 1 1 1 1 Clr5 domain DUF2448 PF10476.9 KXX73671.1 - 0.071 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) AAA_6 PF12774.7 KXX73672.1 - 1.1e-125 419.0 0.0 5.4e-125 416.7 0.0 2.4 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KXX73672.1 - 1.6e-124 416.6 2.8 1.6e-124 416.6 2.8 5.0 5 1 1 6 6 6 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KXX73672.1 - 1.4e-117 393.2 7.1 1.4e-117 393.2 7.1 5.7 5 2 1 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KXX73672.1 - 1.2e-73 246.8 0.4 1.2e-73 246.8 0.4 3.6 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KXX73672.1 - 4.9e-65 219.4 0.0 4.9e-64 216.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KXX73672.1 - 7.8e-42 142.8 0.0 3.2e-36 124.6 0.0 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KXX73672.1 - 8e-39 133.6 13.4 2.2e-38 132.2 9.3 2.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KXX73672.1 - 1.2e-31 109.6 0.0 1.4e-11 44.5 0.0 6.6 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KXX73672.1 - 4.6e-30 104.2 0.0 4.2e-27 94.6 0.0 4.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KXX73672.1 - 2.8e-29 102.0 0.0 6.8e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KXX73672.1 - 7.1e-16 58.7 0.2 0.0096 16.2 0.0 6.9 7 0 0 7 7 6 3 AAA domain Dynein_AAA_lid PF17852.1 KXX73672.1 - 1e-14 54.7 0.0 4.4e-14 52.7 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KXX73672.1 - 3e-13 50.4 0.0 0.0023 18.4 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX73672.1 - 8.7e-10 38.9 2.6 0.11 12.7 0.0 5.2 5 0 0 5 5 4 3 AAA domain AAA_18 PF13238.6 KXX73672.1 - 1.6e-09 38.4 0.3 0.078 13.5 0.0 5.6 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KXX73672.1 - 4.7e-09 36.9 9.2 1.8 8.9 0.0 8.5 9 0 0 9 9 6 1 AAA ATPase domain AAA_lid_1 PF17857.1 KXX73672.1 - 7.3e-06 26.1 0.0 0.00052 20.2 0.0 3.7 3 0 0 3 3 2 1 AAA+ lid domain T2SSE PF00437.20 KXX73672.1 - 7.8e-06 25.1 0.0 0.016 14.3 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXX73672.1 - 1e-05 25.2 0.0 0.73 9.6 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXX73672.1 - 3.1e-05 23.5 1.1 0.67 9.3 0.0 4.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KXX73672.1 - 0.00022 21.8 0.1 4.6 7.8 0.0 4.6 3 0 0 3 3 3 0 ABC transporter AAA_19 PF13245.6 KXX73672.1 - 0.00024 21.5 0.5 0.28 11.5 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KXX73672.1 - 0.00042 19.9 0.1 0.24 11.0 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXX73672.1 - 0.00047 19.9 0.2 11 5.7 0.0 5.2 5 0 0 5 5 4 0 AAA domain FtsK_SpoIIIE PF01580.18 KXX73672.1 - 0.0012 18.2 2.6 2.4 7.5 0.0 4.3 4 0 0 4 4 4 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KXX73672.1 - 0.0014 18.4 0.3 39 3.9 0.0 4.6 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 KXX73672.1 - 0.0039 16.5 0.0 1.4 8.1 0.0 3.6 3 0 0 3 3 3 1 Zeta toxin IstB_IS21 PF01695.17 KXX73672.1 - 0.0054 16.5 0.5 0.65 9.7 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein Pox_A32 PF04665.12 KXX73672.1 - 0.0098 15.4 0.4 18 4.7 0.0 4.4 5 0 0 5 5 4 0 Poxvirus A32 protein RNA_helicase PF00910.22 KXX73672.1 - 0.014 15.7 0.1 41 4.6 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 KXX73672.1 - 0.063 13.2 1.2 6.7 6.6 0.0 3.9 5 0 0 5 5 3 0 Rad17 P-loop domain DUF4482 PF14818.6 KXX73672.1 - 0.082 13.8 9.1 17 6.3 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) NTPase_1 PF03266.15 KXX73672.1 - 0.12 12.3 0.0 39 4.1 0.0 3.9 3 0 0 3 3 2 0 NTPase MbeB_N PF04837.12 KXX73672.1 - 0.26 11.6 3.3 2.6 8.4 0.1 3.8 3 0 0 3 3 2 0 MbeB-like, N-term conserved region Spc7 PF08317.11 KXX73672.1 - 0.28 10.0 35.6 0.1 11.4 13.1 5.1 4 0 0 4 4 4 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KXX73672.1 - 0.87 9.4 19.5 0.65 9.8 6.6 4.0 3 0 0 3 3 2 0 Phage minor structural protein GP20 NACHT PF05729.12 KXX73672.1 - 1.9 8.4 7.3 31 4.4 0.0 4.8 5 0 0 5 5 3 0 NACHT domain LOH1CR12 PF10158.9 KXX73672.1 - 2.7 8.0 8.6 2.3 8.2 0.4 4.8 4 0 0 4 4 4 0 Tumour suppressor protein DUF3867 PF12983.7 KXX73672.1 - 4 7.4 10.9 0.36 10.8 1.7 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF3867) DUF1774 PF08611.10 KXX73673.1 - 2e-37 127.4 6.6 2e-37 127.4 6.6 2.6 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Exo_endo_phos PF03372.23 KXX73674.1 - 3.2e-06 26.8 0.1 8.8e-06 25.4 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXX73674.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase SPRY PF00622.28 KXX73677.1 - 1.5e-19 70.3 0.2 2.7e-19 69.4 0.0 1.5 2 0 0 2 2 2 1 SPRY domain Coilin_N PF15862.5 KXX73678.1 - 0.0047 16.7 0.0 4.8 7.0 5.4 2.4 2 1 0 2 2 2 1 Coilin N-terminus LPD23 PF18838.1 KXX73678.1 - 0.88 9.4 4.4 0.2 11.4 0.3 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 DUF2956 PF11169.8 KXX73678.1 - 2.8 8.2 11.3 8.5 6.6 6.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) But2 PF09792.9 KXX73680.1 - 0.014 15.8 0.0 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain Kinesin PF00225.23 KXX73681.1 - 3.3e-111 371.4 0.1 3.1e-110 368.2 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 KXX73681.1 - 2.9e-52 177.4 0.4 9.1e-52 175.8 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KXX73681.1 - 5.5e-36 124.4 14.3 2.8e-30 105.8 0.4 3.8 2 1 0 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KXX73681.1 - 8.1e-25 87.5 0.1 2.7e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 KXX73681.1 - 1.1e-07 32.2 0.2 1.1e-07 32.2 0.2 2.2 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 KXX73681.1 - 0.019 15.4 0.0 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 PH domain Yop-YscD_cpl PF16697.5 KXX73681.1 - 0.02 15.2 0.0 0.07 13.5 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain E2F_CC-MB PF16421.5 KXX73681.1 - 0.13 12.6 11.8 0.11 12.9 4.5 3.4 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain Peptidase_M1 PF01433.20 KXX73682.1 - 2.3e-43 148.3 0.1 3.5e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KXX73682.1 - 2.1e-40 137.3 0.0 5e-40 136.1 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KXX73682.1 - 8.7e-30 104.3 0.0 1.4e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KXX73682.1 - 0.0068 16.1 0.0 0.047 13.4 0.0 2.2 3 0 0 3 3 3 1 Peptidase MA superfamily Peptidase_M61 PF05299.12 KXX73682.1 - 0.38 11.2 2.3 9.5 6.6 2.4 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase PI3_PI4_kinase PF00454.27 KXX73683.1 - 2e-34 119.5 0.0 6.6e-34 117.8 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KXX73683.1 - 6e-20 71.0 0.0 1.3e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KXX73683.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 KXX73683.1 - 0.15 12.3 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal AA_permease_2 PF13520.6 KXX73684.1 - 3.6e-81 273.2 25.7 4.5e-81 272.9 25.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX73684.1 - 1e-09 37.5 22.6 1.5e-09 37.0 22.6 1.3 1 0 0 1 1 1 1 Amino acid permease Cyd_oper_YbgE PF09600.10 KXX73684.1 - 0.00073 19.9 1.9 0.00073 19.9 1.9 3.6 4 1 1 5 5 5 1 Cyd operon protein YbgE (Cyd_oper_YbgE) Lipase_GDSL_2 PF13472.6 KXX73685.1 - 4.2e-17 63.1 0.3 6.6e-17 62.5 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX73685.1 - 5.7e-10 39.5 0.0 6.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXX73685.1 - 0.0028 17.8 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family kleA_kleC PF17383.2 KXX73686.1 - 0.009 16.3 4.7 0.009 16.3 4.7 4.0 1 1 2 3 3 3 1 Uncharacterized KorC regulated protein A TAP35_44 PF07265.11 KXX73686.1 - 0.035 14.1 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 DUF4665 PF15679.5 KXX73686.1 - 3.1 8.5 13.5 0.86 10.3 2.7 3.4 3 2 1 4 4 4 0 Domain of unknown function (DUF4665) Filament PF00038.21 KXX73686.1 - 6.6 6.2 46.6 0.98 8.9 12.4 3.3 1 1 2 3 3 3 0 Intermediate filament protein FlxA PF14282.6 KXX73686.1 - 8.7 6.4 18.9 2.9 7.9 0.2 4.4 4 2 0 4 4 4 0 FlxA-like protein RasGAP_C PF03836.15 KXX73686.1 - 9.4 6.4 20.8 0.48 10.6 0.1 3.8 1 1 1 3 3 3 0 RasGAP C-terminus Alpha_kinase PF02816.18 KXX73688.1 - 5.7e-52 176.5 0.0 8.6e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KXX73688.1 - 8.3e-13 48.9 0.0 3.2e-12 47.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXX73688.1 - 3.1e-05 24.3 0.0 7.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain GAS PF13851.6 KXX73688.1 - 0.0055 16.1 9.9 0.38 10.1 0.6 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding RPA_interact_M PF14767.6 KXX73688.1 - 0.59 10.8 2.8 2.3 8.9 0.7 2.5 2 0 0 2 2 2 0 Replication protein A interacting middle MPS2 PF17060.5 KXX73688.1 - 0.98 8.6 2.7 1.7 7.9 2.7 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 FAD_binding_4 PF01565.23 KXX73690.1 - 1.1e-30 106.2 0.0 1.8e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DLH PF01738.18 KXX73691.1 - 1.7e-15 57.2 0.0 1e-14 54.6 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family OPT PF03169.15 KXX73692.1 - 2.5e-170 568.1 52.6 2.9e-170 567.9 52.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.25 KXX73694.1 - 3.8e-34 117.9 0.0 2.2e-33 115.4 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73694.1 - 2.5e-26 92.7 0.0 2.6e-25 89.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXX73694.1 - 8.6e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KXX73694.1 - 0.00038 20.4 0.0 0.0094 15.9 0.0 2.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXX73694.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 KXX73694.1 - 0.086 12.3 0.0 0.59 9.5 0.0 2.3 3 1 0 3 3 3 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX73694.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding ABC2_membrane PF01061.24 KXX73695.1 - 7.3e-38 130.1 48.8 1.4e-19 70.4 11.3 4.0 4 1 1 5 5 5 3 ABC-2 type transporter PDR_CDR PF06422.12 KXX73695.1 - 2.8e-30 104.1 13.0 1.1e-28 98.9 0.0 4.3 4 0 0 4 4 4 2 CDR ABC transporter ABC_tran PF00005.27 KXX73695.1 - 5.1e-09 36.8 0.0 0.00019 22.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXX73695.1 - 0.0055 16.2 0.0 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KXX73695.1 - 0.54 9.3 22.4 0.6 9.2 9.5 3.2 2 2 1 3 3 3 0 ABC-2 family transporter protein DUF4079 PF13301.6 KXX73695.1 - 3.7 7.7 12.6 0.04 14.1 3.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) DUF2070 PF09843.9 KXX73695.1 - 3.8 5.7 8.5 7.7 4.7 8.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC_tran PF00005.27 KXX73696.1 - 4.7e-06 27.2 0.0 6.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.6 KXX73696.1 - 5.6e-05 23.7 0.2 0.00019 22.0 0.1 1.9 2 0 0 2 2 2 1 ABC-transporter N-terminal adh_short PF00106.25 KXX73697.1 - 1e-19 70.7 0.0 6.5e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX73697.1 - 8.4e-16 58.2 0.0 2.9e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX73697.1 - 2e-08 34.4 0.1 3.4e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX73697.1 - 0.0074 15.8 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KXX73697.1 - 0.082 12.1 0.3 0.2 10.9 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXX73697.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXX73697.1 - 0.15 12.7 0.6 0.25 11.9 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SMP PF04927.12 KXX73698.1 - 1.6e-10 41.3 12.8 5e-07 30.1 3.1 2.2 1 1 1 2 2 2 2 Seed maturation protein PPR_2 PF13041.6 KXX73699.1 - 2.4e-44 149.3 8.9 6e-09 36.0 0.0 11.9 11 3 4 15 15 15 8 PPR repeat family PPR_3 PF13812.6 KXX73699.1 - 2.1e-34 117.4 0.0 0.0006 19.8 0.0 10.7 9 3 3 12 12 12 7 Pentatricopeptide repeat domain PPR PF01535.20 KXX73699.1 - 5.6e-27 92.1 20.9 0.00018 21.5 0.1 14.2 16 0 0 16 16 16 5 PPR repeat PPR_1 PF12854.7 KXX73699.1 - 2e-21 75.4 0.0 9.2e-08 31.7 0.0 9.3 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 KXX73699.1 - 3.3e-17 62.6 17.1 1.2e-07 31.4 0.1 7.6 5 2 4 9 9 9 7 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KXX73699.1 - 0.00053 20.4 0.0 0.0045 17.4 0.0 2.6 2 1 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 KXX73699.1 - 0.0014 18.5 0.2 0.022 14.6 0.1 3.1 1 1 1 2 2 2 1 Mitochondrial ATPase expression GHMP_kinases_N PF00288.26 KXX73700.1 - 2.3e-17 63.0 1.0 2.3e-17 63.0 1.0 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXX73700.1 - 2.8e-06 27.6 0.0 6.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal DDHD PF02862.17 KXX73702.1 - 3e-25 89.7 0.0 3e-24 86.4 0.0 2.1 1 1 0 1 1 1 1 DDHD domain Abhydrolase_1 PF00561.20 KXX73702.1 - 0.017 14.8 0.0 0.054 13.1 0.0 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX73702.1 - 0.059 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KXX73702.1 - 0.087 12.4 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Na_Ca_ex PF01699.24 KXX73703.1 - 4.6e-32 111.1 39.7 6.9e-18 65.0 17.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YL1 PF05764.13 KXX73703.1 - 0.023 14.8 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TMEM208_SND2 PF05620.11 KXX73703.1 - 0.3 10.8 4.1 13 5.6 0.8 2.7 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Nop14 PF04147.12 KXX73703.1 - 2.8 6.1 4.8 3.8 5.6 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family p450 PF00067.22 KXX73706.1 - 3.5e-65 220.6 0.0 4.3e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTV_P6 PF06706.11 KXX73706.1 - 0.068 12.9 0.4 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein TauD PF02668.16 KXX73707.1 - 1.3e-44 153.0 0.1 1.8e-44 152.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SIR2 PF02146.17 KXX73708.1 - 2.6e-25 89.4 0.5 7.9e-18 65.0 0.0 2.9 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KXX73708.1 - 0.017 14.8 0.0 4 7.2 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TauD PF02668.16 KXX73708.1 - 0.088 12.6 0.0 1.6 8.5 0.0 2.0 1 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family GRDP-like PF07173.12 KXX73709.1 - 2.2e-18 67.3 10.2 2.4e-14 54.2 0.3 4.0 3 1 1 4 4 4 3 Glycine-rich domain-containing protein-like Use1 PF09753.9 KXX73709.1 - 2.5 7.7 10.6 4 7.1 10.6 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DJ-1_PfpI PF01965.24 KXX73710.1 - 2.6e-16 59.9 0.0 3.2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family adh_short_C2 PF13561.6 KXX73711.1 - 2.2e-48 164.9 0.6 2.9e-48 164.5 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX73711.1 - 8.4e-44 149.4 4.0 9.9e-44 149.1 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX73711.1 - 8.7e-05 22.5 0.7 0.00011 22.2 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX73711.1 - 0.0022 17.5 0.3 0.0066 15.9 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX73711.1 - 0.016 15.1 0.8 0.022 14.7 0.8 1.2 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 KXX73711.1 - 0.045 13.6 1.1 0.082 12.8 1.1 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXX73711.1 - 0.056 14.2 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KXX73712.1 - 4.2e-40 137.7 50.4 4.5e-39 134.4 25.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX73712.1 - 2.7e-16 59.5 15.4 3.4e-16 59.2 0.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter PTR2 PF00854.21 KXX73712.1 - 0.00087 18.2 0.2 0.0021 16.9 0.2 1.6 1 0 0 1 1 1 1 POT family Presenilin PF01080.17 KXX73712.1 - 0.027 13.2 7.5 0.056 12.2 7.5 1.5 1 0 0 1 1 1 0 Presenilin DIT1_PvcA PF05141.12 KXX73713.1 - 7.1e-99 330.7 0.0 8.8e-99 330.4 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AltA1 PF16541.5 KXX73715.1 - 3.7e-26 92.2 2.8 5.9e-26 91.5 2.8 1.3 1 0 0 1 1 1 1 Alternaria alternata allergen 1 BsuPI PF12690.7 KXX73716.1 - 0.016 15.3 0.1 0.061 13.4 0.0 1.8 2 0 0 2 2 2 0 Intracellular proteinase inhibitor Glyco_hydro_79C PF16862.5 KXX73717.1 - 5e-22 78.7 0.9 5e-22 78.7 0.9 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain MMR_HSR1 PF01926.23 KXX73719.1 - 5.4e-08 32.9 0.0 7.1e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX73719.1 - 3.4e-06 27.1 0.0 7.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KXX73719.1 - 1.1e-05 25.6 0.8 0.1 12.7 0.2 2.8 2 1 1 3 3 3 2 Dynamin family Septin PF00735.18 KXX73719.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 KXX73719.1 - 1.9e-05 24.1 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 KXX73719.1 - 0.00021 21.7 0.1 0.0026 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXX73719.1 - 0.00097 19.7 0.0 0.004 17.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KXX73719.1 - 0.0011 19.2 0.1 0.0044 17.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXX73719.1 - 0.0015 18.1 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 KXX73719.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF815 PF05673.13 KXX73719.1 - 0.0017 17.6 0.0 0.0046 16.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 KXX73719.1 - 0.0069 16.5 0.2 0.016 15.3 0.1 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 KXX73719.1 - 0.0074 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 KXX73719.1 - 0.0092 15.9 0.1 0.027 14.4 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 KXX73719.1 - 0.0096 16.5 2.7 0.02 15.5 0.2 2.6 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KXX73719.1 - 0.01 15.6 0.2 0.33 10.7 0.3 2.2 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KXX73719.1 - 0.011 16.2 0.1 0.038 14.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXX73719.1 - 0.011 16.0 0.5 0.02 15.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_5 PF07728.14 KXX73719.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KXX73719.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Roc PF08477.13 KXX73719.1 - 0.022 14.9 0.1 0.086 13.1 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 KXX73719.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 KXX73719.1 - 0.023 14.8 0.3 0.083 13.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX73719.1 - 0.033 13.9 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KXX73719.1 - 0.036 13.2 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit CIDR1_gamma PF18562.1 KXX73719.1 - 0.047 13.8 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma SMC_N PF02463.19 KXX73719.1 - 0.048 13.1 0.0 0.52 9.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Gtr1_RagA PF04670.12 KXX73719.1 - 0.051 12.9 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KXX73719.1 - 0.07 12.7 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Ras family Ploopntkinase3 PF18751.1 KXX73719.1 - 0.079 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Pox_A32 PF04665.12 KXX73719.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein TsaE PF02367.17 KXX73719.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PPV_E1_C PF00519.17 KXX73719.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase IstB_IS21 PF01695.17 KXX73719.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_PrkA PF08298.11 KXX73719.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_23 PF13476.6 KXX73719.1 - 0.18 12.3 0.3 0.32 11.5 0.0 1.5 2 0 0 2 2 1 0 AAA domain AIG1 PF04548.16 KXX73720.1 - 1e-09 38.1 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KXX73720.1 - 1.9e-09 37.6 0.0 4.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXX73720.1 - 0.0042 17.1 5.6 0.64 10.1 0.0 3.1 2 2 1 3 3 3 2 Dynamin family ABC_tran PF00005.27 KXX73720.1 - 0.016 15.7 1.0 0.056 14.0 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KXX73720.1 - 0.058 13.1 0.1 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KXX73720.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXX73720.1 - 0.19 11.6 2.5 0.39 10.6 0.8 2.2 2 1 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KXX73720.1 - 0.24 11.9 6.9 1.9 8.9 3.5 2.2 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 KXX73720.1 - 0.31 11.4 2.8 0.51 10.7 2.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 KXX73720.1 - 3.2 7.8 7.3 0.69 10.0 0.8 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Sec8_exocyst PF04048.14 KXX73723.1 - 3.5e-50 169.6 0.3 8e-50 168.4 0.3 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KXX73723.1 - 5.2e-10 39.1 1.8 9.7e-10 38.2 1.8 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KXX73723.1 - 0.026 13.1 2.2 0.062 11.9 2.1 1.6 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 ATP-grasp_4 PF13535.6 KXX73723.1 - 0.085 12.4 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Swi5 PF07061.11 KXX73723.1 - 0.095 12.8 0.3 0.34 11.0 0.3 2.0 1 0 0 1 1 1 0 Swi5 Occludin_ELL PF07303.13 KXX73723.1 - 0.36 11.6 1.7 1.5 9.6 0.1 2.9 2 1 1 3 3 3 0 Occludin homology domain IZUMO PF15005.6 KXX73723.1 - 0.43 11.1 1.6 1.1 9.7 0.4 2.4 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Pkinase PF00069.25 KXX73724.1 - 2.4e-67 227.1 0.0 3.3e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73724.1 - 4.1e-47 160.6 0.0 6e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX73724.1 - 1.8e-05 23.8 0.2 4.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXX73724.1 - 0.0011 18.4 0.0 0.0043 16.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Chorion_2 PF03964.15 KXX73724.1 - 2.3 9.1 6.6 4.3 8.2 3.7 2.3 1 1 0 2 2 2 0 Chorion family 2 DUF676 PF05057.14 KXX73725.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXX73725.1 - 5.8e-05 22.5 0.1 0.00013 21.3 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 KXX73725.1 - 0.00024 21.1 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 KXX73725.1 - 0.00037 21.2 0.0 0.00044 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXX73725.1 - 0.00066 19.5 0.0 0.00081 19.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_9 PF10081.9 KXX73725.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Lipase_3 PF01764.25 KXX73725.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 KXX73725.1 - 0.016 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF726 PF05277.12 KXX73725.1 - 0.02 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) LIDHydrolase PF10230.9 KXX73725.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Palm_thioest PF02089.15 KXX73725.1 - 0.023 14.6 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_8 PF06259.12 KXX73725.1 - 0.047 13.3 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase SMI1_KNR4 PF09346.10 KXX73726.1 - 1.2e-32 113.1 0.0 2.3e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.11 KXX73727.1 - 3.5e-56 189.3 3.0 3.8e-56 189.2 3.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) BNIP3 PF06553.12 KXX73727.1 - 0.075 12.7 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 BNIP3 RAI1 PF08652.11 KXX73728.1 - 9e-28 96.3 0.0 3.2e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease RSRP PF17069.5 KXX73728.1 - 0.16 11.5 9.3 0.26 10.9 9.3 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Pap_E4 PF02711.14 KXX73728.1 - 1.5 9.8 8.3 3.1 8.8 8.3 1.4 1 0 0 1 1 1 0 E4 protein Transglut_core PF01841.19 KXX73729.1 - 1.2e-11 45.0 0.2 2.9e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KXX73729.1 - 2.1e-08 33.7 0.1 4.8e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXX73729.1 - 6.7e-05 22.4 0.1 6.7e-05 22.4 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXX73729.1 - 0.015 15.1 0.2 0.036 13.9 0.2 1.7 1 0 0 1 1 1 0 Variant SH3 domain ABC_tran PF00005.27 KXX73730.1 - 5.6e-15 56.1 0.0 1.2e-08 35.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXX73730.1 - 2.4e-10 40.7 0.3 0.00019 21.4 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KXX73730.1 - 0.00078 17.1 0.2 0.001 16.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KXX73730.1 - 0.0012 18.5 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXX73730.1 - 0.0017 17.9 0.0 0.94 8.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXX73730.1 - 0.0089 16.6 0.1 0.012 16.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXX73730.1 - 0.01 16.3 0.1 0.075 13.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXX73730.1 - 0.011 16.0 0.9 0.038 14.2 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX73730.1 - 0.011 16.1 1.5 0.046 14.1 1.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXX73730.1 - 0.023 15.0 0.1 0.059 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KXX73730.1 - 0.028 14.1 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXX73730.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 KXX73730.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KXX73730.1 - 0.05 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXX73730.1 - 0.053 13.7 0.2 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KXX73730.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXX73730.1 - 0.16 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.21 KXX73730.1 - 0.17 11.3 0.4 0.29 10.6 0.4 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.12 KXX73730.1 - 0.2 11.6 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 NACHT domain Aldedh PF00171.22 KXX73731.1 - 2.5e-132 441.7 0.0 2.8e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_2 PF12796.7 KXX73732.1 - 2.8e-50 168.8 4.5 3.6e-16 59.5 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX73732.1 - 5e-47 157.7 8.5 4e-09 36.8 0.0 6.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX73732.1 - 8.7e-39 131.1 7.0 3.4e-09 36.8 0.3 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX73732.1 - 5.9e-34 112.3 1.8 0.00052 20.2 0.0 7.5 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KXX73732.1 - 2.1e-32 110.1 4.8 1.5e-05 25.2 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat SPT_ssu-like PF11779.8 KXX73733.1 - 0.08 12.6 0.5 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Carb_bind PF10645.9 KXX73734.1 - 3.3e-22 78.4 5.8 8e-22 77.2 5.8 1.7 1 0 0 1 1 1 1 Carbohydrate binding CorA PF01544.18 KXX73737.1 - 6e-26 91.4 4.3 2.6e-22 79.5 1.8 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein WD40 PF00400.32 KXX73738.1 - 2.6e-106 344.5 74.1 2.3e-08 34.5 0.2 14.4 15 0 0 15 15 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX73738.1 - 1.8e-32 111.5 17.6 0.0083 16.4 0.0 13.4 3 1 12 15 15 14 10 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXX73738.1 - 1.2e-18 67.6 0.0 2.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KXX73738.1 - 4.1e-17 62.0 28.7 0.34 9.5 0.1 12.1 4 3 7 12 12 12 8 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXX73738.1 - 3.8e-09 36.0 23.1 1.5 7.7 1.0 9.7 2 2 6 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_2 PF12796.7 KXX73738.1 - 7.2e-06 26.5 0.0 0.00097 19.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) WD40_like PF17005.5 KXX73738.1 - 7.5e-06 25.5 0.0 0.11 11.7 0.0 4.1 4 0 0 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KXX73738.1 - 3.8e-05 22.6 14.6 0.092 11.5 0.2 6.0 1 1 2 6 6 6 2 Nup133 N terminal like PD40 PF07676.12 KXX73738.1 - 0.00057 19.8 0.4 21 5.2 0.0 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ank PF00023.30 KXX73738.1 - 0.00061 20.1 0.0 0.0041 17.5 0.0 2.5 2 0 0 2 2 1 1 Ankyrin repeat AAA_16 PF13191.6 KXX73738.1 - 0.0024 18.3 0.6 0.025 15.0 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Ank_5 PF13857.6 KXX73738.1 - 0.011 16.0 0.0 0.042 14.2 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AAA_19 PF13245.6 KXX73738.1 - 0.035 14.4 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_3 PF13606.6 KXX73738.1 - 0.059 14.0 0.0 1.1 10.1 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KXX73738.1 - 0.084 13.5 0.0 0.49 11.0 0.0 2.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Methyltransf_PK PF05891.12 KXX73739.1 - 3.1e-55 187.1 0.1 4.5e-54 183.3 0.1 1.9 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 KXX73739.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX73739.1 - 0.011 16.4 0.0 0.025 15.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KXX73739.1 - 0.043 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_11 PF08241.12 KXX73739.1 - 0.064 13.9 0.0 0.11 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain SAM_2 PF07647.17 KXX73742.1 - 1.4e-14 53.9 0.1 2.4e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KXX73742.1 - 8.2e-14 51.2 0.0 1.6e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXX73742.1 - 9e-12 44.4 0.0 1.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KXX73742.1 - 6.3e-08 33.1 0.0 3.3e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 KXX73742.1 - 0.00088 18.9 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KXX73742.1 - 0.021 15.2 0.1 0.072 13.5 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain DUF1704 PF08014.11 KXX73742.1 - 0.065 12.2 0.1 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1704) PH_8 PF15409.6 KXX73742.1 - 0.083 13.2 0.0 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.30 KXX73742.1 - 0.091 13.2 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pox_I6 PF04595.13 KXX73742.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family DUF952 PF06108.12 KXX73743.1 - 1.2e-24 86.1 0.0 1.5e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Nucleopor_Nup85 PF07575.13 KXX73744.1 - 3.1e-16 59.1 0.0 3e-14 52.5 0.0 2.8 1 1 0 1 1 1 1 Nup85 Nucleoporin zf-AN1 PF01428.16 KXX73745.1 - 2.5e-11 43.6 10.9 3.1e-11 43.2 9.7 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KXX73745.1 - 0.28 11.6 7.4 0.49 10.8 7.4 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain IBR PF01485.21 KXX73745.1 - 0.61 10.4 8.4 0.32 11.2 6.5 1.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain ADH_N PF08240.12 KXX73746.1 - 3.3e-26 91.3 1.2 7.5e-26 90.2 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX73746.1 - 2.5e-20 72.8 0.3 4.6e-20 71.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXX73746.1 - 0.002 17.4 0.3 0.0035 16.7 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXX73746.1 - 0.011 16.8 0.0 0.022 15.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KXX73746.1 - 0.012 15.2 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXX73746.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KXX73746.1 - 0.065 13.8 0.2 0.24 12.0 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KXX73746.1 - 0.075 13.3 0.7 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KXX73746.1 - 0.11 11.8 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF676 PF05057.14 KXX73747.1 - 3.1e-51 174.0 0.0 7.2e-51 172.8 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KXX73747.1 - 0.00024 21.8 1.1 0.0007 20.3 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KXX73747.1 - 0.02 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 KXX73747.1 - 0.021 14.5 0.0 0.16 11.7 0.0 2.0 1 1 0 1 1 1 0 PGAP1-like protein Lipase_2 PF01674.18 KXX73747.1 - 0.22 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) HhH-GPD PF00730.25 KXX73748.1 - 3.1e-16 59.8 0.0 5.6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXX73748.1 - 9.7e-08 31.5 0.0 2.5e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif TPR_10 PF13374.6 KXX73750.1 - 3.5e-95 309.7 13.0 7.2e-14 51.1 0.1 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KXX73750.1 - 9.3e-87 285.4 35.7 6.2e-17 61.7 0.2 6.3 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KXX73750.1 - 4.6e-25 85.8 13.1 0.0025 17.7 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KXX73750.1 - 4.1e-18 64.0 8.2 0.0064 16.6 0.1 7.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX73750.1 - 1.4e-17 62.7 16.3 0.0045 16.8 0.2 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat DUF1925 PF09094.11 KXX73750.1 - 1.2e-12 48.0 1.5 7.2 7.0 0.0 7.4 7 0 0 7 7 7 0 Domain of unknown function (DUF1925) NB-ARC PF00931.22 KXX73750.1 - 1.7e-08 34.0 0.0 4.7e-08 32.5 0.0 1.8 2 0 0 2 2 1 1 NB-ARC domain TPR_17 PF13431.6 KXX73750.1 - 3.7e-08 33.2 5.8 5.7 7.6 0.0 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX73750.1 - 4.6e-08 33.4 11.7 0.052 14.1 0.0 6.7 2 1 6 8 8 7 2 Tetratricopeptide repeat Get5_bdg PF16843.5 KXX73750.1 - 1.5e-07 30.8 0.1 12 5.5 0.0 5.3 5 0 0 5 5 5 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein TPR_2 PF07719.17 KXX73750.1 - 1.1e-06 28.3 14.5 4.3 7.7 0.2 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat Nro1 PF12753.7 KXX73750.1 - 1.2e-06 27.8 0.1 1 8.3 0.0 5.1 1 1 5 6 6 6 1 Nuclear pore complex subunit Nro1 TPR_MalT PF17874.1 KXX73750.1 - 2.6e-05 23.8 5.3 0.035 13.5 1.8 2.4 2 0 0 2 2 2 2 MalT-like TPR region Abhydrolase_6 PF12697.7 KXX73750.1 - 4.4e-05 24.2 0.1 0.00012 22.8 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3856 PF12968.7 KXX73750.1 - 8.1e-05 22.7 1.3 0.51 10.4 0.1 3.4 1 1 1 3 3 3 3 Domain of Unknown Function (DUF3856) AAA_16 PF13191.6 KXX73750.1 - 0.00015 22.2 0.5 0.00063 20.2 0.2 2.3 2 1 0 2 2 1 1 AAA ATPase domain Lactate_perm PF02652.14 KXX73750.1 - 0.00019 20.3 0.0 28 3.3 0.0 5.0 1 1 5 6 6 6 0 L-lactate permease kleA_kleC PF17383.2 KXX73750.1 - 0.0033 17.7 19.2 31 5.0 0.1 6.7 6 0 0 6 6 6 0 Uncharacterized KorC regulated protein A Wzy_C_2 PF11846.8 KXX73750.1 - 0.0066 16.4 3.9 0.85 9.5 0.0 4.0 1 1 2 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal TPR_14 PF13428.6 KXX73750.1 - 0.0078 16.9 12.9 7.3 7.7 0.0 8.1 8 1 1 9 9 8 0 Tetratricopeptide repeat PGAP1 PF07819.13 KXX73750.1 - 0.0099 15.6 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KXX73750.1 - 0.01 15.3 0.0 0.038 13.5 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) MLD PF11647.8 KXX73750.1 - 0.012 15.8 4.1 6.1 7.2 0.1 4.1 1 1 4 5 5 5 0 Membrane Localization Domain Hydrolase_4 PF12146.8 KXX73750.1 - 0.069 12.4 0.1 0.19 11.0 0.0 1.7 2 0 0 2 2 1 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KXX73750.1 - 0.097 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase CorA PF01544.18 KXX73750.1 - 0.12 11.7 10.0 16 4.7 0.2 4.4 2 1 3 5 5 5 0 CorA-like Mg2+ transporter protein CK2S PF15011.6 KXX73750.1 - 0.37 10.7 4.4 2e+02 1.8 0.0 4.8 5 0 0 5 5 5 0 Casein Kinase 2 substrate DUF2680 PF10925.8 KXX73750.1 - 1.3 9.1 13.4 1.6e+02 2.4 0.1 6.0 6 0 0 6 6 6 0 Protein of unknown function (DUF2680) TPR_16 PF13432.6 KXX73750.1 - 1.6 9.5 6.2 9.9 6.9 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXX73750.1 - 1.8 8.6 4.7 55 3.9 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.19 KXX73751.1 - 3.8e-60 203.6 0.0 5.1e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXX73751.1 - 0.00049 19.2 0.0 0.00078 18.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cwf_Cwc_15 PF04889.12 KXX73752.1 - 0.37 10.5 8.6 0.6 9.8 8.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 KXX73752.1 - 1.5 9.5 8.0 4.6 8.0 8.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CFEM PF05730.11 KXX73753.1 - 0.0042 17.2 2.9 0.0042 17.2 2.9 2.4 2 0 0 2 2 2 1 CFEM domain Peptidase_M24 PF00557.24 KXX73754.1 - 2.9e-50 170.9 0.2 3.9e-50 170.5 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXX73754.1 - 1.7e-35 121.4 0.0 2.6e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HLH PF00010.26 KXX73755.1 - 1.4e-15 56.9 0.1 7.7e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.6 KXX73755.1 - 0.05 14.0 1.9 0.091 13.2 1.9 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 PPE PF00823.19 KXX73755.1 - 0.2 11.7 0.1 0.35 11.0 0.1 1.3 1 0 0 1 1 1 0 PPE family T5orf172 PF10544.9 KXX73756.1 - 2.7e-15 56.8 0.8 3.5e-15 56.4 0.8 1.2 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KXX73756.1 - 1.6e-07 31.9 0.6 2.4e-07 31.3 0.6 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 zf-C2H2_4 PF13894.6 KXX73757.1 - 0.025 15.4 0.2 0.048 14.5 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger bVLRF1 PF18826.1 KXX73758.1 - 2.2e-63 212.6 0.0 3.8e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KXX73758.1 - 8.5e-08 32.3 0.1 2.2e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXX73758.1 - 0.00081 19.7 0.4 0.0021 18.4 0.4 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KXX73758.1 - 0.032 14.8 0.0 0.067 13.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RNA_pol_3_Rpc31 PF11705.8 KXX73758.1 - 0.032 14.5 1.2 0.032 14.5 1.2 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 F-box-like PF12937.7 KXX73759.1 - 0.0031 17.4 0.0 0.015 15.2 0.0 2.3 2 1 0 2 2 2 1 F-box-like ASCH PF04266.14 KXX73760.1 - 3.4e-12 46.9 0.0 4.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ASCH domain Methyltransf_2 PF00891.18 KXX73761.1 - 2.7e-24 85.6 0.0 4.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain PHO4 PF01384.20 KXX73763.1 - 8.2e-95 317.7 15.3 1e-94 317.3 15.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KXX73763.1 - 0.45 10.8 8.6 1.1 9.6 0.8 2.7 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 DUF4134 PF13572.6 KXX73763.1 - 0.99 9.7 9.6 0.87 9.9 2.9 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4134) Glyco_hydro_16 PF00722.21 KXX73764.1 - 1e-10 41.4 0.1 1.4e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.18 KXX73764.1 - 1e-08 35.0 10.0 3.2e-08 33.4 10.0 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain HET PF06985.11 KXX73767.1 - 6.9e-23 81.6 0.0 2.8e-22 79.6 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KXX73768.1 - 1e-13 50.9 70.3 1.2e-11 44.2 34.4 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KXX73768.1 - 7.7e-08 31.2 27.4 1.2e-07 30.6 27.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rhabdo_glycop PF00974.18 KXX73768.1 - 0.066 11.7 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Pyr_redox_2 PF07992.14 KXX73769.1 - 9.9e-33 113.6 0.0 7.7e-30 104.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX73769.1 - 1.1e-10 41.9 0.3 3.2e-09 37.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXX73769.1 - 0.00021 20.3 0.1 0.34 9.7 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase K_oxygenase PF13434.6 KXX73769.1 - 0.0027 16.9 0.1 0.0077 15.4 0.1 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXX73769.1 - 0.0044 17.0 0.9 10 6.1 0.0 4.2 5 0 0 5 5 5 1 FAD-NAD(P)-binding DAO PF01266.24 KXX73769.1 - 0.0081 15.8 0.5 3.5 7.1 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXX73769.1 - 0.019 14.0 0.3 1.1 8.3 0.0 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 KXX73769.1 - 0.025 13.3 0.0 2.7 6.6 0.0 3.2 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_2 PF00890.24 KXX73769.1 - 0.037 13.1 0.4 4.4 6.3 0.1 2.9 3 1 1 4 4 4 0 FAD binding domain NAD_binding_8 PF13450.6 KXX73769.1 - 0.052 13.8 0.0 2.6 8.3 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX73769.1 - 0.11 11.7 0.1 0.29 10.3 0.0 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX73769.1 - 0.12 11.6 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain CFEM PF05730.11 KXX73770.1 - 9.1e-11 41.7 5.0 1.3e-10 41.2 5.0 1.3 1 0 0 1 1 1 1 CFEM domain UPRTase PF14681.6 KXX73771.1 - 2.3e-34 118.6 0.1 4e-34 117.9 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 KXX73771.1 - 2.2e-21 77.1 0.4 6.5e-21 75.6 0.4 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KXX73771.1 - 8.2e-16 58.7 0.0 2.2e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX73771.1 - 1.7e-06 28.6 2.0 4.5e-06 27.2 0.4 2.4 2 1 1 3 3 2 1 AAA ATPase domain Pribosyltran PF00156.27 KXX73771.1 - 0.00032 20.3 0.1 0.0016 18.0 0.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_18 PF13238.6 KXX73771.1 - 0.00052 20.6 0.0 0.0016 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.26 KXX73771.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_22 PF13401.6 KXX73771.1 - 0.0023 18.2 0.4 0.014 15.6 0.0 2.5 2 1 1 3 3 3 1 AAA domain KAP_NTPase PF07693.14 KXX73771.1 - 0.0023 17.2 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain MeaB PF03308.16 KXX73771.1 - 0.0046 16.0 0.0 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KXX73771.1 - 0.011 15.5 0.1 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXX73771.1 - 0.017 15.6 0.0 0.15 12.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRTase_2 PF15609.6 KXX73771.1 - 0.031 13.8 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase Thymidylate_kin PF02223.17 KXX73771.1 - 0.052 13.2 0.3 1.5 8.4 0.0 3.0 2 1 1 3 3 3 0 Thymidylate kinase NB-ARC PF00931.22 KXX73771.1 - 0.06 12.5 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KXX73771.1 - 0.076 12.9 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KXX73771.1 - 0.11 12.4 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Peptidase_U4 PF03419.13 KXX73771.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA AAA_5 PF07728.14 KXX73771.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 KXX73771.1 - 0.16 11.4 0.0 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KXX73771.1 - 0.17 12.3 0.0 0.75 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KXX73771.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXX73771.1 - 0.34 11.1 2.4 0.59 10.3 0.0 2.6 3 1 1 4 4 2 0 AAA domain MatE PF01554.18 KXX73772.1 - 7.2e-51 172.0 33.6 2.9e-31 108.3 10.4 2.7 2 1 1 3 3 3 2 MatE YhhN PF07947.14 KXX73773.1 - 3e-39 134.6 17.9 4.7e-39 133.9 17.9 1.3 1 0 0 1 1 1 1 YhhN family TMEM219 PF14940.6 KXX73773.1 - 0.12 11.9 0.8 0.22 11.1 0.8 1.4 1 0 0 1 1 1 0 Transmembrane 219 DUF2070 PF09843.9 KXX73773.1 - 1.9 6.7 9.9 2.3 6.4 9.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PrgI PF12666.7 KXX73773.1 - 4.7 8.0 11.1 0.14 12.8 3.4 2.5 1 1 1 2 2 2 0 PrgI family protein Acetyltransf_1 PF00583.25 KXX73774.1 - 4.6e-07 30.1 0.0 8.7e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX73774.1 - 6.8e-07 29.3 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX73774.1 - 2.9e-06 27.6 0.1 1e-05 25.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXX73774.1 - 0.00098 19.2 0.2 0.0018 18.4 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LPMO_10 PF03067.15 KXX73775.1 - 9.6e-08 32.9 1.8 7.5e-05 23.5 0.0 2.1 1 1 1 2 2 2 2 Lytic polysaccharide mono-oxygenase, cellulose-degrading CDH-cyt PF16010.5 KXX73776.1 - 1.8e-51 174.4 2.9 2.1e-51 174.2 2.9 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase vATP-synt_E PF01991.18 KXX73777.1 - 1.2e-64 217.4 6.0 1.5e-64 217.1 6.0 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit ENTH PF01417.20 KXX73777.1 - 0.0056 16.7 0.4 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 ENTH domain DUF2255 PF10012.9 KXX73777.1 - 0.34 11.1 2.4 0.34 11.1 0.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) CdiI_2 PF18593.1 KXX73777.1 - 0.45 11.2 2.4 1.1 10.0 0.1 2.4 2 1 0 2 2 2 0 CdiI immunity protein SurA_N_3 PF13624.6 KXX73777.1 - 1.9 8.3 8.5 1.2 8.9 2.5 2.4 2 1 1 3 3 3 0 SurA N-terminal domain zf-C2H2 PF00096.26 KXX73779.1 - 2.8e-08 33.8 11.4 3.5e-05 24.0 0.8 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX73779.1 - 7.7e-07 29.3 16.4 4.5e-05 23.7 1.7 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX73779.1 - 9.7e-06 26.0 9.4 0.0013 19.4 0.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX73779.1 - 0.0012 19.1 3.2 0.04 14.2 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXX73779.1 - 0.012 15.6 5.5 1.4 9.1 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXX73779.1 - 0.39 10.5 2.4 19 5.2 0.1 3.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KXX73779.1 - 0.72 10.3 3.6 0.76 10.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KXX73779.1 - 2.3 8.7 9.3 1.5 9.3 2.0 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SRF-TF PF00319.18 KXX73780.1 - 4.5e-21 74.1 0.1 6.3e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MRI PF15325.6 KXX73780.1 - 7.1 7.8 5.9 1.7 9.8 0.3 2.3 2 1 0 2 2 2 0 Modulator of retrovirus infection Ctr PF04145.15 KXX73781.1 - 6.1e-30 104.8 0.4 8.3e-30 104.4 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Mg_trans_NIPA PF05653.14 KXX73782.1 - 2e-14 53.4 9.6 2.9e-14 52.9 9.6 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXX73782.1 - 0.00058 20.0 2.8 0.00058 20.0 2.8 2.8 3 1 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KXX73782.1 - 0.00098 18.4 0.4 0.00098 18.4 0.4 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 KXX73782.1 - 0.0042 16.4 0.2 0.0071 15.6 0.2 1.4 1 0 0 1 1 1 1 UAA transporter family Tetraspanin PF00335.20 KXX73783.1 - 0.0029 17.4 8.3 0.0081 15.9 8.3 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF2371 PF10177.9 KXX73783.1 - 0.15 12.3 0.4 16 5.7 0.0 2.4 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF4191 PF13829.6 KXX73783.1 - 1 8.6 0.0 1 8.6 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DUF3684 PF12449.8 KXX73784.1 - 0 1477.1 0.0 0 1476.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KXX73784.1 - 3.1e-05 23.8 0.0 7.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.6 KXX73784.1 - 0.0089 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 MMtag PF10159.9 KXX73785.1 - 8.4e-32 109.3 0.6 8.4e-32 109.3 0.6 2.0 2 0 0 2 2 2 1 Multiple myeloma tumor-associated adh_short_C2 PF13561.6 KXX73786.1 - 3.3e-57 193.7 3.9 1.1e-56 192.1 3.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX73786.1 - 2.7e-36 124.8 2.2 5.8e-26 91.2 0.6 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXX73786.1 - 2.3e-10 40.7 1.2 4.9e-09 36.4 0.2 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXX73786.1 - 0.00074 19.0 0.1 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KXX73786.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXX73786.1 - 0.046 14.0 0.1 0.08 13.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 KXX73786.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.15 KXX73786.1 - 0.097 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.19 KXX73786.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PALP PF00291.25 KXX73786.1 - 0.55 9.6 4.2 1.6 8.0 0.6 2.0 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme Metallophos PF00149.28 KXX73787.1 - 9.9e-38 130.7 0.1 1.8e-37 129.8 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAC3 PF10178.9 KXX73788.1 - 0.0002 21.5 0.0 0.00025 21.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 TauD PF02668.16 KXX73789.1 - 6.2e-20 72.1 0.0 7.7e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXX73789.1 - 0.088 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 CsiD HA2 PF04408.23 KXX73790.1 - 6.8e-26 90.7 0.0 6.8e-26 90.7 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXX73790.1 - 2.1e-12 47.2 0.0 4.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXX73790.1 - 1.4e-11 44.7 0.0 9e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX73790.1 - 1.1e-08 35.1 0.1 4.6e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KXX73790.1 - 0.00013 22.3 0.0 0.00033 21.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXX73790.1 - 0.00039 20.2 0.0 0.0013 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX73790.1 - 0.00059 20.1 0.2 0.0029 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KXX73790.1 - 0.0071 16.9 10.5 0.0099 16.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KXX73790.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KXX73790.1 - 0.045 12.8 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KXX73790.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC 2-Hacid_dh_C PF02826.19 KXX73791.1 - 2.6e-49 167.0 0.0 4.8e-49 166.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXX73791.1 - 1.1e-15 57.5 0.0 1.6e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXX73791.1 - 0.00099 19.3 0.0 0.0035 17.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KXX73791.1 - 0.0075 15.6 0.1 0.5 9.6 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_L27A PF00828.19 KXX73792.1 - 9.3e-21 74.8 0.0 1.5e-20 74.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Med6 PF04934.14 KXX73793.1 - 5.9e-36 123.2 0.0 9e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Phosphodiest PF01663.22 KXX73794.1 - 9.8e-15 55.0 0.4 2.6e-14 53.6 0.4 1.7 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXX73794.1 - 0.00065 19.2 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KXX73794.1 - 0.0044 16.4 0.6 0.0078 15.6 0.6 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Meth_synt_2 PF01717.18 KXX73795.1 - 5.8e-147 489.2 0.0 2.2e-143 477.4 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXX73795.1 - 7.7e-120 400.1 0.0 8.4e-114 380.3 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KXX73795.1 - 0.0025 17.1 0.0 0.86 8.7 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) Tli4_N PF18443.1 KXX73795.1 - 0.16 12.4 0.1 7 7.0 0.1 2.6 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain EF-hand_4 PF12763.7 KXX73796.1 - 1.9e-26 92.0 0.0 1.7e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KXX73796.1 - 9.7e-05 21.7 0.0 0.21 11.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXX73796.1 - 0.00024 21.5 0.6 0.42 11.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KXX73796.1 - 0.00099 18.9 0.0 6.2 7.0 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain E3_binding PF02817.17 KXX73796.1 - 0.12 12.7 0.2 0.43 11.0 0.2 2.0 1 0 0 1 1 1 0 e3 binding domain Trp_DMAT PF11991.8 KXX73797.1 - 1.6e-97 327.2 0.0 2e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase SnoaL_2 PF12680.7 KXX73798.1 - 0.096 13.3 0.0 0.31 11.7 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain AMP-binding PF00501.28 KXX73799.1 - 4.5e-76 256.1 0.0 8e-76 255.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXX73799.1 - 1.8e-67 228.0 0.0 4e-40 137.9 0.0 2.9 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KXX73799.1 - 6.1e-08 32.9 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site IgaA PF07095.11 KXX73800.1 - 0.012 13.6 0.1 0.015 13.3 0.1 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA LapA_dom PF06305.11 KXX73800.1 - 0.035 13.9 1.3 0.057 13.2 1.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2244 PF10003.9 KXX73800.1 - 0.042 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) EphA2_TM PF14575.6 KXX73800.1 - 0.11 13.3 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SRTM1 PF15872.5 KXX73800.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 DUF5527 PF17665.1 KXX73800.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Herpes_gE PF02480.16 KXX73800.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4083 PF13314.6 KXX73800.1 - 0.27 11.2 4.2 0.55 10.2 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF3377 PF11857.8 KXX73800.1 - 0.31 11.0 1.3 0.59 10.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) zf-C2H2 PF00096.26 KXX73801.1 - 2e-05 24.8 12.4 0.08 13.4 4.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type Glyco_hydro_3_C PF01915.22 KXX73801.1 - 0.006 16.6 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain zf-C2H2_4 PF13894.6 KXX73801.1 - 0.032 15.1 10.3 6.4 7.9 3.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3450 PF11932.8 KXX73801.1 - 0.039 13.2 7.6 0.059 12.7 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 KXX73801.1 - 0.063 12.3 1.5 0.093 11.8 1.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2_aberr PF17017.5 KXX73801.1 - 0.11 12.7 2.0 0.14 12.2 0.1 2.1 3 0 0 3 3 3 0 Aberrant zinc-finger TMF_DNA_bd PF12329.8 KXX73801.1 - 0.37 10.8 4.0 0.68 10.0 4.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-H2C2_5 PF13909.6 KXX73801.1 - 4.2 7.2 6.9 0.78 9.5 0.7 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Ribosomal_60s PF00428.19 KXX73801.1 - 8.1 7.1 10.6 0.31 11.6 3.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein PALP PF00291.25 KXX73802.1 - 2.5e-45 155.2 0.8 3e-45 154.9 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Na_Ala_symp PF01235.17 KXX73802.1 - 0.06 12.6 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Sodium:alanine symporter family Peripla_BP_4 PF13407.6 KXX73802.1 - 0.088 12.4 0.6 14 5.1 0.0 2.9 2 1 1 3 3 3 0 Periplasmic binding protein domain LYTB PF02401.18 KXX73802.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 LytB protein Pkinase PF00069.25 KXX73803.1 - 1e-72 244.7 0.0 2e-72 243.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73803.1 - 7.8e-49 166.3 0.0 1.6e-48 165.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX73803.1 - 0.00012 21.0 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXX73803.1 - 0.019 14.3 0.0 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like FPN1 PF06963.12 KXX73804.1 - 0.076 11.6 2.4 0.11 11.0 2.4 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) ERG4_ERG24 PF01222.17 KXX73805.1 - 6.3e-134 447.0 18.4 7.6e-134 446.7 18.4 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3989 PF13150.6 KXX73805.1 - 0.33 10.7 0.9 20 5.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF218 PF02698.17 KXX73806.1 - 1e-06 28.8 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain Mur_ligase_M PF08245.12 KXX73807.1 - 1.8e-06 28.1 0.0 2.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KXX73807.1 - 0.03 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain SCNM1_acidic PF15805.5 KXX73809.1 - 0.021 14.6 1.3 0.04 13.6 1.3 1.4 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DLH PF01738.18 KXX73809.1 - 0.1 12.1 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family LysM PF01476.20 KXX73811.1 - 2.2e-20 72.4 0.1 0.0029 17.6 0.0 6.2 6 0 0 6 6 6 6 LysM domain Astacin PF01400.24 KXX73812.1 - 0.00062 19.4 0.7 0.053 13.1 0.5 3.4 4 0 0 4 4 4 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KXX73812.1 - 0.027 14.3 0.4 0.21 11.4 0.8 2.2 2 1 0 2 2 2 0 Matrixin Reprolysin_5 PF13688.6 KXX73812.1 - 0.035 14.3 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXX73812.1 - 0.045 13.4 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXX73812.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KXX73812.1 - 0.19 10.6 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Pox_Ag35 PF03286.14 KXX73813.1 - 0.2 11.5 1.3 0.28 10.9 1.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DHR10 PF18595.1 KXX73813.1 - 1.2 9.2 3.0 23 5.1 0.0 2.7 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DUF3433 PF11915.8 KXX73814.1 - 9.8e-09 35.6 6.9 0.00031 21.1 2.6 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF3433) Chlorosome_CsmC PF11098.8 KXX73814.1 - 0.019 15.0 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C Glyco_hydro_18 PF00704.28 KXX73815.1 - 7.2e-66 223.0 0.0 8.7e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXX73815.1 - 1.1e-09 38.6 16.7 4.1e-09 36.8 8.0 2.6 2 0 0 2 2 2 2 Chitin recognition protein Fungal_lectin_2 PF18647.1 KXX73816.1 - 1.1e-39 134.9 0.6 1.1e-39 134.9 0.6 2.0 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 KXX73816.1 - 1.6e-14 54.7 0.1 9.1e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX73816.1 - 3.8e-07 30.3 0.0 1.2e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ADH_zinc_N PF00107.26 KXX73817.1 - 1.9e-09 37.6 0.3 3.1e-09 36.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX73817.1 - 9.5e-07 28.7 0.0 2.5e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.18 KXX73818.1 - 8.9e-12 44.6 0.1 1.3e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX73818.1 - 4.1e-09 36.4 7.4 4.1e-09 36.4 7.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXX73819.1 - 9.5e-06 24.8 19.2 9.5e-06 24.8 19.2 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXX73820.1 - 6e-19 68.2 14.3 1.1e-13 50.9 4.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX73820.1 - 2.5e-06 26.7 0.8 3.1e-06 26.3 0.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KXX73820.1 - 0.056 11.8 5.5 0.072 11.5 5.5 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector FAD_binding_3 PF01494.19 KXX73821.1 - 1.3e-13 51.0 0.5 2.4e-05 23.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXX73821.1 - 0.013 15.7 0.3 0.043 14.0 0.1 2.1 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KXX73821.1 - 0.04 13.2 0.3 0.073 12.4 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain VWA_2 PF13519.6 KXX73821.1 - 0.08 13.6 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4524 PF15025.6 KXX73821.1 - 0.25 11.1 0.8 0.81 9.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) Methyltransf_2 PF00891.18 KXX73822.1 - 8.5e-11 41.5 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HET PF06985.11 KXX73823.1 - 7.3e-10 39.4 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 KXX73824.1 - 1.3e-75 254.9 0.0 1.6e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXX73825.1 - 8.7e-17 61.4 5.3 2.3e-11 43.6 1.0 2.9 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXX73825.1 - 3.9e-06 26.2 0.0 6.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX73825.1 - 4.8e-06 26.0 3.2 3.8e-05 23.1 3.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX73825.1 - 3.3e-05 23.9 0.0 7e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 KXX73825.1 - 5.3e-05 23.0 7.6 0.00028 20.6 3.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX73825.1 - 0.0013 17.9 0.2 0.0025 17.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXX73825.1 - 0.0018 18.8 0.9 0.013 16.0 0.7 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXX73825.1 - 0.0023 16.8 3.5 0.076 11.9 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 KXX73825.1 - 0.0074 15.6 0.2 0.013 14.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXX73825.1 - 0.011 16.0 4.3 0.013 15.7 0.6 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXX73825.1 - 0.011 15.0 0.3 0.6 9.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KXX73825.1 - 0.036 13.3 0.0 0.79 8.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXX73825.1 - 0.043 12.9 0.3 0.062 12.4 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXX73825.1 - 0.15 10.7 0.5 0.23 10.1 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein ADH_zinc_N PF00107.26 KXX73826.1 - 9.2e-10 38.6 0.1 2.7e-09 37.1 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX73826.1 - 4e-07 29.9 0.1 1.1e-05 25.3 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain FAD_binding_4 PF01565.23 KXX73827.1 - 3.5e-18 65.7 0.5 4.4e-11 42.7 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.12 KXX73827.1 - 2.6e-08 33.8 0.0 6.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like BTB PF00651.31 KXX73828.1 - 0.065 13.5 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 BTB/POZ domain SRP19 PF01922.17 KXX73829.1 - 1.8e-32 112.2 0.0 2.9e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein SWI-SNF_Ssr4 PF08549.10 KXX73829.1 - 0.14 10.8 3.3 0.18 10.4 3.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) CCDC53 PF10152.9 KXX73829.1 - 1.3 9.4 4.7 2 8.8 4.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 KXX73829.1 - 3.8 7.1 7.1 5.2 6.6 7.1 1.1 1 0 0 1 1 1 0 Spt20 family OMPdecase PF00215.24 KXX73830.1 - 3.3e-99 331.1 0.1 4.8e-99 330.5 0.1 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Dak2 PF02734.17 KXX73830.1 - 0.098 12.5 3.6 0.17 11.8 3.6 1.5 1 0 0 1 1 1 0 DAK2 domain CDP-OH_P_transf PF01066.21 KXX73831.1 - 1.5e-12 48.1 0.2 1.5e-12 48.1 0.2 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cyt-b5 PF00173.28 KXX73832.1 - 3.9e-18 65.4 0.8 1.3e-17 63.7 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KXX73832.1 - 1.2e-12 48.3 18.5 1.2e-12 48.3 18.5 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KXX73832.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.22 KXX73833.1 - 0.00011 21.9 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Host_attach PF10116.9 KXX73833.1 - 7.8 7.1 19.3 0.11 13.0 5.1 2.7 1 1 2 3 3 3 0 Protein required for attachment to host cells PP2C PF00481.21 KXX73834.1 - 1.4e-35 123.2 0.0 3.3e-30 105.6 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXX73834.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein phosphatase 2C YrzK PF17449.2 KXX73834.1 - 0.12 12.7 0.1 0.36 11.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized YrzK-like Het-C PF07217.11 KXX73835.1 - 4.5e-286 949.8 0.0 5.5e-286 949.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Dynactin PF12455.8 KXX73836.1 - 2.3e-115 384.8 8.8 2.3e-115 384.8 8.8 3.6 5 0 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 KXX73836.1 - 1e-24 86.3 0.7 1.9e-24 85.4 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 KXX73836.1 - 0.00029 20.3 24.0 0.00029 20.3 24.0 4.6 4 1 0 5 5 5 2 Uncharacterized coiled-coil protein (DUF2353) Fungal_trans PF04082.18 KXX73837.1 - 2.7e-10 39.8 3.2 2.5e-07 30.0 0.0 3.7 4 0 0 4 4 4 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX73837.1 - 7.2e-07 29.2 11.5 1.3e-06 28.5 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX73838.1 - 2.6e-22 79.1 0.0 2.4e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX73838.1 - 8.4e-09 35.4 7.4 1.7e-08 34.5 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX73839.1 - 1.6e-50 172.0 0.0 2.1e-24 86.1 0.0 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX73839.1 - 0.00025 21.1 7.2 0.0005 20.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 KXX73839.1 - 4.4 7.3 55.5 0.54 10.2 48.9 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein SPESP1 PF15754.5 KXX73839.1 - 9.5 5.3 9.5 17 4.5 9.5 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Podoplanin PF05808.11 KXX73840.1 - 0.0057 16.8 2.0 0.013 15.6 2.0 1.5 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 KXX73840.1 - 0.019 15.8 0.2 0.049 14.5 0.2 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KXX73840.1 - 0.036 14.0 0.6 0.083 12.8 0.6 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4834 PF16118.5 KXX73840.1 - 0.89 10.6 1.8 2.5 9.1 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) FAD_binding_3 PF01494.19 KXX73842.1 - 4.7e-73 246.4 0.0 6.1e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXX73842.1 - 2.1e-40 138.4 0.1 4.8e-40 137.3 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KXX73842.1 - 0.00047 19.5 0.0 0.007 15.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX73842.1 - 0.0016 19.0 0.0 0.0044 17.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX73842.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX73842.1 - 0.018 14.7 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXX73842.1 - 0.026 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KXX73842.1 - 0.058 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.6 KXX73842.1 - 0.079 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 KXX73842.1 - 0.091 11.8 0.0 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXX73842.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Fasciclin PF02469.22 KXX73844.1 - 9.8e-15 54.9 0.0 1.1e-12 48.3 0.0 2.6 3 0 0 3 3 3 2 Fasciclin domain SnoaL_4 PF13577.6 KXX73845.1 - 1.9e-52 176.7 4.6 1.5e-19 70.4 0.1 3.6 4 0 0 4 4 4 3 SnoaL-like domain Big_3_5 PF16640.5 KXX73845.1 - 1.2e-05 25.3 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) SnoaL_3 PF13474.6 KXX73845.1 - 0.0061 16.8 0.3 0.24 11.7 0.0 3.2 2 1 0 2 2 2 1 SnoaL-like domain RSN1_7TM PF02714.15 KXX73846.1 - 2.1e-83 279.8 11.6 2.1e-83 279.8 11.6 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXX73846.1 - 1.2e-41 142.1 0.5 1.2e-41 142.1 0.5 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXX73846.1 - 8.1e-27 94.6 0.0 1.2e-26 94.0 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXX73846.1 - 3e-25 88.2 2.0 1.2e-24 86.3 0.1 2.6 3 0 0 3 3 3 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KXX73846.1 - 0.17 11.7 0.0 0.53 10.1 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4448 PF14610.6 KXX73850.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM240 PF15207.6 KXX73850.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 TMEM240 family Mito_fiss_reg PF05308.11 KXX73850.1 - 7 6.6 6.2 4.9 7.2 2.6 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator MFS_1 PF07690.16 KXX73851.1 - 1.4e-55 188.7 46.1 2.3e-43 148.5 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXX73851.1 - 1.1e-09 37.4 3.1 1.1e-09 37.4 3.1 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.20 KXX73851.1 - 1.5e-05 23.5 6.3 6.4e-05 21.4 2.7 2.6 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family RRP7 PF12923.7 KXX73852.1 - 6.3e-30 103.8 8.9 6.3e-30 103.8 8.9 1.7 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KXX73852.1 - 3.1e-18 66.1 0.0 6.3e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain ADIP PF11559.8 KXX73853.1 - 8e-44 149.4 8.7 8e-44 149.4 8.7 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KXX73853.1 - 0.02 14.4 9.4 0.016 14.7 7.6 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4472 PF14739.6 KXX73853.1 - 2.9 8.6 7.2 8.3 7.2 6.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Fez1 PF06818.15 KXX73853.1 - 6.7 7.1 14.4 0.53 10.7 7.8 2.4 2 1 1 3 3 3 0 Fez1 DivIVA PF05103.13 KXX73853.1 - 7.9 6.6 12.0 58 3.8 0.1 2.6 2 0 0 2 2 2 0 DivIVA protein NmrA PF05368.13 KXX73854.1 - 1e-08 35.0 0.0 5.8e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX73854.1 - 4.6e-07 29.9 0.0 4.8e-06 26.6 0.0 2.4 3 0 0 3 3 3 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXX73854.1 - 6.9e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXX73854.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KXX73854.1 - 0.079 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KXX73854.1 - 0.17 12.5 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CsbD PF05532.12 KXX73855.1 - 9.4e-19 67.1 19.8 3.2e-12 46.2 1.6 3.1 2 1 1 3 3 3 3 CsbD-like F-box PF00646.33 KXX73856.1 - 0.0019 18.0 0.7 0.0037 17.1 0.7 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX73856.1 - 0.84 9.6 3.3 0.41 10.6 0.6 2.0 2 0 0 2 2 2 0 F-box-like MOSC PF03473.17 KXX73857.1 - 1.8e-24 86.2 0.0 6.2e-24 84.5 0.0 2.0 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.27 KXX73857.1 - 6e-10 38.9 0.7 1.3e-09 37.8 0.7 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 KXX73857.1 - 1.9e-05 24.4 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 KXX73857.1 - 0.0023 18.6 0.1 0.12 13.0 0.0 3.0 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 KXX73857.1 - 0.088 12.6 2.2 0.19 11.5 2.2 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Aminotran_5 PF00266.19 KXX73858.1 - 5.8e-95 318.4 0.0 7e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXX73858.1 - 2.7e-06 26.9 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXX73858.1 - 6.7e-06 25.7 0.1 2.1e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KXX73858.1 - 0.0017 17.2 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KXX73858.1 - 0.056 12.0 0.0 0.085 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BAR PF03114.18 KXX73859.1 - 8.6e-69 231.8 10.0 1.1e-68 231.5 10.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KXX73859.1 - 5.6e-15 54.7 0.2 1.2e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXX73859.1 - 4.3e-11 42.5 0.0 7.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX73859.1 - 1.5e-08 34.2 0.1 1.1e-07 31.4 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain TMPIT PF07851.13 KXX73859.1 - 0.12 11.6 8.5 0.41 9.8 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Amidase PF01425.21 KXX73860.1 - 5.4e-30 104.7 0.6 1.8e-29 103.0 0.3 1.8 2 0 0 2 2 2 1 Amidase C1_1 PF00130.22 KXX73861.1 - 0.019 14.9 0.8 0.034 14.0 0.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Desulfoferrod_N PF06397.12 KXX73861.1 - 0.21 11.2 1.3 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF1168 PF06658.12 KXX73862.1 - 3.9e-38 130.4 12.8 5.2e-38 129.9 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4407 PF14362.6 KXX73862.1 - 0.031 13.6 2.4 0.033 13.5 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3292 PF11696.8 KXX73862.1 - 0.7 8.2 4.3 0.94 7.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) MFAP1 PF06991.11 KXX73862.1 - 0.74 9.6 21.2 1.1 9.1 21.2 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing RR_TM4-6 PF06459.12 KXX73862.1 - 0.87 9.4 7.6 1.2 8.9 7.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KXX73862.1 - 1.4 7.6 4.4 1.4 7.6 4.4 1.1 1 0 0 1 1 1 0 Presenilin Med19 PF10278.9 KXX73862.1 - 4.4 7.2 15.6 6.7 6.6 15.6 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.14 KXX73862.1 - 4.4 5.5 10.4 5.6 5.1 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol3_a_NII PF11490.8 KXX73862.1 - 8.3 6.3 11.7 12 5.9 11.7 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF5401 PF17380.2 KXX73862.1 - 9.4 4.2 21.1 13 3.7 21.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) 3Beta_HSD PF01073.19 KXX73863.1 - 6.7e-25 87.6 0.0 1.1e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXX73863.1 - 9.1e-13 48.2 0.1 7.5e-12 45.2 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXX73863.1 - 4.9e-09 35.7 0.0 3e-06 26.6 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 KXX73863.1 - 4.4e-05 23.5 0.0 9.3e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXX73863.1 - 0.00012 21.4 0.0 0.00022 20.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX73863.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KXX73863.1 - 0.0021 18.0 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 KR domain His_Phos_1 PF00300.22 KXX73864.1 - 7.1e-28 97.6 0.0 1.4e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KXX73864.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) P5-ATPase PF12409.8 KXX73864.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter SKG6 PF08693.10 KXX73865.1 - 5.3e-10 38.5 5.6 1e-09 37.6 5.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KXX73865.1 - 0.00027 20.9 0.1 0.00027 20.9 0.1 2.6 3 1 0 3 3 3 1 TMEM154 protein family CD34_antigen PF06365.12 KXX73865.1 - 0.006 16.2 0.0 0.0086 15.7 0.0 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4448 PF14610.6 KXX73865.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CcmD PF04995.14 KXX73865.1 - 0.05 13.7 0.5 0.083 13.0 0.5 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) EphA2_TM PF14575.6 KXX73865.1 - 0.12 13.2 0.0 0.22 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 KXX73865.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT IncD PF17628.2 KXX73865.1 - 0.21 11.4 0.4 0.32 10.8 0.4 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D DUF4381 PF14316.6 KXX73865.1 - 0.23 11.7 0.0 0.39 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PAP_PilO PF06864.12 KXX73865.1 - 0.23 10.3 0.0 0.23 10.3 0.0 2.4 2 0 0 2 2 2 0 Pilin accessory protein (PilO) HECT PF00632.25 KXX73866.1 - 2.9e-52 178.1 0.0 7.2e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Cpn60_TCP1 PF00118.24 KXX73867.1 - 3.3e-172 573.5 1.0 3.8e-172 573.3 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KXX73867.1 - 0.039 13.6 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 BRK domain NAD_binding_10 PF13460.6 KXX73869.1 - 1.2e-09 38.4 0.0 3.1e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX73869.1 - 9.4e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family SMP_LBD PF17047.5 KXX73870.1 - 2.9e-23 82.2 0.2 4e-23 81.8 0.2 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KXX73870.1 - 1.2e-20 73.7 0.0 8.2e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain Glycos_transf_N PF04413.16 KXX73870.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) NHL PF01436.21 KXX73871.1 - 3.6e-05 23.6 0.0 1.2 9.3 0.0 4.2 3 1 1 4 4 4 2 NHL repeat SBBP PF06739.11 KXX73871.1 - 9.4e-05 22.3 0.2 0.47 10.5 0.0 3.3 3 0 0 3 3 3 2 Beta-propeller repeat SGL PF08450.12 KXX73871.1 - 0.0002 21.1 0.0 0.12 12.0 0.0 3.1 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KXX73871.1 - 0.01 15.1 0.2 1.9 7.6 0.2 2.3 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller GSDH PF07995.11 KXX73871.1 - 0.021 14.2 3.1 0.58 9.4 0.1 3.2 4 0 0 4 4 4 0 Glucose / Sorbosone dehydrogenase RCC1_2 PF13540.6 KXX73871.1 - 0.059 13.2 2.0 5.7 6.9 0.1 3.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 KXX73873.1 - 1.8e-07 31.7 5.7 0.36 11.8 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat FAD_binding_3 PF01494.19 KXX73874.1 - 5.7e-15 55.4 0.2 2.2e-13 50.2 0.2 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX73874.1 - 0.047 13.9 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain p450 PF00067.22 KXX73875.1 - 6.2e-28 97.7 0.0 3.2e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 WD40 PF00400.32 KXX73876.1 - 5.3e-30 103.0 11.8 4.2e-09 36.9 0.3 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX73876.1 - 3.8e-12 46.3 2.6 3.5e-05 24.0 0.2 4.2 3 1 2 5 5 4 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXX73876.1 - 5.6e-09 36.1 0.1 3.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Nup160 PF11715.8 KXX73876.1 - 7.5e-08 31.5 3.6 0.093 11.4 0.3 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 AAA_16 PF13191.6 KXX73876.1 - 4e-06 27.3 0.9 1.5e-05 25.5 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 KXX73876.1 - 0.00011 21.6 0.2 0.00019 20.8 0.2 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Nbas_N PF15492.6 KXX73876.1 - 0.0045 16.4 4.2 4 6.7 0.1 3.4 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal AAA PF00004.29 KXX73876.1 - 0.013 16.0 0.1 0.044 14.2 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ge1_WD40 PF16529.5 KXX73876.1 - 0.017 14.1 2.8 0.47 9.4 2.8 2.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KXX73876.1 - 0.022 13.7 5.3 0.25 10.2 0.4 2.3 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain APS_kinase PF01583.20 KXX73876.1 - 0.041 13.8 0.1 0.096 12.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KXX73876.1 - 0.084 13.4 1.1 0.51 10.9 0.1 2.9 3 1 0 3 3 3 0 AAA domain CbiA PF01656.23 KXX73876.1 - 0.12 12.4 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KXX73876.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase KAP_NTPase PF07693.14 KXX73876.1 - 0.18 11.0 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain DUF1045 PF06299.12 KXX73877.1 - 0.093 12.7 0.4 0.18 11.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) OTU PF02338.19 KXX73878.1 - 1.2e-18 67.9 0.2 9e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXX73878.1 - 3.1e-06 26.8 0.0 0.00049 19.6 0.0 2.7 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF4407 PF14362.6 KXX73878.1 - 0.034 13.5 13.4 0.046 13.1 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short_C2 PF13561.6 KXX73879.1 - 1.7e-44 152.1 0.0 3.9e-44 151.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX73879.1 - 1e-41 142.6 0.0 1.9e-41 141.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX73879.1 - 2.1e-09 37.5 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 KR domain GST_N_4 PF17172.4 KXX73881.1 - 1.5e-15 57.7 0.0 1.6e-14 54.4 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXX73881.1 - 6.8e-07 29.0 0.0 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXX73881.1 - 2.9e-06 27.6 0.1 9.8e-06 25.9 0.1 1.9 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KXX73881.1 - 0.001 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 KXX73881.1 - 0.0023 17.9 0.5 0.0083 16.1 0.2 1.9 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Mcp5_PH PF12814.7 KXX73882.1 - 9.8e-47 158.1 0.0 1.9e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KXX73882.1 - 6.2e-05 23.5 15.5 6.2e-05 23.5 15.5 1.7 2 0 0 2 2 2 1 Fez1 GAS PF13851.6 KXX73882.1 - 0.011 15.1 13.3 0.017 14.5 13.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YkyA PF10368.9 KXX73882.1 - 0.11 12.2 12.2 0.0094 15.6 5.5 2.0 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.12 KXX73882.1 - 0.23 11.5 24.2 0.057 13.5 13.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.9 KXX73882.1 - 0.32 9.5 11.2 0.53 8.8 11.2 1.2 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 KXX73882.1 - 1.4 8.4 5.9 2.7 7.5 5.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4337 PF14235.6 KXX73882.1 - 2.2 8.4 3.5 4.1 7.5 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Seryl_tRNA_N PF02403.22 KXX73882.1 - 2.5 8.4 7.5 1.5 9.1 4.5 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 KXX73882.1 - 3.4 7.5 5.5 4.1 7.2 0.0 2.4 1 1 1 2 2 2 0 Septum formation initiator Spc7 PF08317.11 KXX73882.1 - 6.3 5.6 15.3 11 4.9 15.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 KXX73882.1 - 7.9 6.5 12.2 35 4.4 1.7 3.0 3 0 0 3 3 3 0 Prefoldin subunit DUF724 PF05266.14 KXX73882.1 - 8.2 6.2 11.5 1.4 8.7 7.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Hydrolase PF00702.26 KXX73883.1 - 7.3e-10 39.5 0.0 1.2e-09 38.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXX73883.1 - 7.8e-09 35.9 0.0 1.9e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXX73883.1 - 1.2e-07 31.6 0.1 2.9e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Voltage_CLC PF00654.20 KXX73884.1 - 1.8e-90 303.7 20.3 1.8e-90 303.7 20.3 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel Paf1 PF03985.13 KXX73885.1 - 8.3e-92 308.4 1.6 9.4e-92 308.2 1.6 1.0 1 0 0 1 1 1 1 Paf1 Herpes_UL49_2 PF04823.12 KXX73885.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Ribosomal_L7Ae PF01248.26 KXX73886.1 - 4.9e-28 96.7 0.7 6.3e-28 96.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KXX73886.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF1846 PF08903.11 KXX73886.1 - 0.17 10.4 0.1 0.21 10.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Rotamase_3 PF13616.6 KXX73887.1 - 7e-18 65.3 0.4 1.3e-17 64.4 0.4 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KXX73887.1 - 2.1e-16 60.6 0.3 3.6e-16 59.9 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KXX73887.1 - 4.6e-05 24.2 0.2 7.6e-05 23.5 0.2 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Glyco_transf_90 PF05686.12 KXX73888.1 - 0.12 11.3 7.7 1.7 7.5 4.0 2.9 2 1 0 2 2 2 0 Glycosyl transferase family 90 Ribosomal_S8 PF00410.19 KXX73889.1 - 2.2e-22 79.4 0.1 2.9e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 TCTP PF00838.17 KXX73891.1 - 2.8e-67 226.2 1.3 3.1e-67 226.1 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Herpes_UL46 PF03387.14 KXX73891.1 - 0.015 14.0 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL46 protein Neurochondrin PF05536.11 KXX73892.1 - 2.7e-107 359.6 0.0 4.6e-107 358.9 0.0 1.3 1 1 0 1 1 1 1 Neurochondrin RIX1 PF08167.12 KXX73892.1 - 0.0035 17.1 1.5 0.012 15.4 0.4 2.5 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Voltage_CLC PF00654.20 KXX73893.1 - 6.5e-90 301.9 27.2 6.5e-90 301.9 27.2 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXX73893.1 - 0.00068 20.0 0.0 0.043 14.3 0.0 2.5 2 0 0 2 2 2 1 CBS domain LacI PF00356.21 KXX73893.1 - 0.74 9.7 1.9 1.9 8.3 1.9 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family NRDE-2 PF08424.10 KXX73894.1 - 9.1e-93 310.9 0.0 1.6e-91 306.8 0.0 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KXX73894.1 - 0.0018 18.9 9.0 3.8 8.6 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat WW PF00397.26 KXX73895.1 - 0.35 11.0 5.7 1.2 9.3 5.7 1.9 1 0 0 1 1 1 0 WW domain DUF3439 PF11921.8 KXX73895.1 - 4.6 7.2 11.1 0.27 11.2 5.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Glyco_hydro_16 PF00722.21 KXX73896.1 - 4.4e-11 42.6 1.9 6.3e-11 42.1 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Prok-E2_E PF14462.6 KXX73896.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E ketoacyl-synt PF00109.26 KXX73897.1 - 6.3e-62 209.4 6.1 2.5e-60 204.2 0.6 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXX73897.1 - 1.6e-35 121.7 2.6 2.4e-35 121.1 1.8 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXX73897.1 - 2e-06 27.3 0.1 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX73897.1 - 0.0011 18.6 3.8 0.011 15.3 0.3 3.4 3 1 0 3 3 3 1 Thiolase, C-terminal domain DUF348 PF03990.14 KXX73897.1 - 0.012 15.3 0.2 1.4 8.8 0.4 2.8 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain KAsynt_C_assoc PF16197.5 KXX73897.1 - 0.16 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension PSI_PSAK PF01241.18 KXX73897.1 - 0.26 11.3 4.1 2.4 8.2 0.2 3.4 2 2 1 3 3 3 0 Photosystem I psaG / psaK OPT PF03169.15 KXX73898.1 - 1.1e-187 625.5 44.0 1.2e-187 625.3 44.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dioxygenase_C PF00775.21 KXX73899.1 - 2.3e-49 167.3 0.0 3.1e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXX73899.1 - 9.1e-26 89.5 0.2 1.4e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXX73899.1 - 1.5e-06 28.4 0.0 1e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.18 KXX73900.1 - 1.9e-24 86.2 0.0 3.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX73900.1 - 1.1e-05 25.5 16.3 2e-05 24.6 16.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Biotin_lipoyl PF00364.22 KXX73902.1 - 6.3e-21 74.0 0.5 1.2e-20 73.1 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXX73902.1 - 5.1e-10 39.5 0.1 2e-09 37.7 0.1 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KXX73902.1 - 0.00024 20.9 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXX73902.1 - 0.0048 17.6 0.3 1.2 9.9 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein QRPTase_N PF02749.16 KXX73902.1 - 0.16 12.1 0.0 0.59 10.2 0.0 1.9 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain CoA_transf_3 PF02515.17 KXX73903.1 - 3.2e-35 122.0 0.3 1.6e-32 113.1 0.1 2.3 2 0 0 2 2 2 2 CoA-transferase family III Spidroin_N PF16763.5 KXX73903.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Pkinase PF00069.25 KXX73904.1 - 7.3e-76 255.0 0.0 9.3e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73904.1 - 2.2e-37 128.7 0.0 3.2e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXX73904.1 - 0.0018 17.3 0.0 0.022 13.7 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXX73904.1 - 0.04 13.3 0.1 0.076 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SCA7 PF08313.12 KXX73905.1 - 1.8e-31 107.8 0.3 5.1e-31 106.4 0.3 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Omega-toxin PF06357.11 KXX73905.1 - 0.13 12.1 0.2 0.32 10.8 0.2 1.7 1 0 0 1 1 1 0 Omega-atracotoxin zf_C2HC_14 PF18574.1 KXX73905.1 - 0.16 11.8 2.1 0.28 11.0 2.1 1.3 1 0 0 1 1 1 0 C2HC Zing finger domain Acyltransferase PF01553.21 KXX73906.1 - 1.8e-14 53.5 0.0 2.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PH_9 PF15410.6 KXX73907.1 - 1.9e-09 37.9 0.0 2.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3099 PF11298.8 KXX73907.1 - 0.11 12.7 0.3 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) NTF2 PF02136.20 KXX73908.1 - 2e-25 89.7 0.2 3.3e-25 89.0 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KXX73908.1 - 5.7e-08 32.5 0.2 1e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXX73908.1 - 0.0027 17.7 0.0 0.011 15.8 0.0 2.1 1 0 0 1 1 1 1 RNA binding motif Nnf1 PF03980.14 KXX73909.1 - 8.9e-26 90.4 5.5 8.9e-26 90.4 5.5 1.9 2 0 0 2 2 2 1 Nnf1 TPR_MLP1_2 PF07926.12 KXX73909.1 - 0.0029 17.7 1.9 0.0029 17.7 1.9 2.3 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein YqjK PF13997.6 KXX73909.1 - 0.0065 16.7 1.0 0.1 12.8 0.0 2.3 2 0 0 2 2 2 1 YqjK-like protein DUF641 PF04859.12 KXX73909.1 - 0.011 16.1 1.8 0.022 15.1 0.7 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Syntaxin-6_N PF09177.11 KXX73909.1 - 0.019 15.5 1.1 0.13 12.9 1.1 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal SHE3 PF17078.5 KXX73909.1 - 0.059 13.1 0.4 0.087 12.5 0.4 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 RVT_3 PF13456.6 KXX73909.1 - 0.063 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DivIC PF04977.15 KXX73909.1 - 0.068 13.0 1.0 0.068 13.0 1.0 2.4 3 0 0 3 3 3 0 Septum formation initiator ZapB PF06005.12 KXX73909.1 - 0.075 13.5 1.4 0.075 13.5 1.4 2.6 3 0 0 3 3 3 0 Cell division protein ZapB PI3K_P85_iSH2 PF16454.5 KXX73909.1 - 0.11 12.1 3.0 0.16 11.6 3.0 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 KXX73909.1 - 0.12 11.7 3.0 0.16 11.3 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSNAXIP1_N PF15739.5 KXX73909.1 - 0.79 10.1 4.3 0.26 11.7 1.1 1.8 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus COMP PF11598.8 KXX73909.1 - 1.3 9.5 6.6 1.2 9.7 1.8 2.7 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein DUF5595 PF18077.1 KXX73909.1 - 1.7 8.8 3.8 1.1 9.4 0.3 2.3 2 1 2 4 4 4 0 Domain of unknown function (DUF5595) Med21 PF11221.8 KXX73909.1 - 2.8 8.2 9.6 0.19 12.0 0.7 2.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex APG6_N PF17675.1 KXX73909.1 - 3.8 8.0 8.5 5.4 7.5 7.3 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region zf-RING_UBOX PF13445.6 KXX73910.1 - 1.1e-08 34.9 10.0 1.4e-05 25.0 3.7 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 KXX73910.1 - 4.2e-08 33.2 0.0 1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 KXX73910.1 - 4.2e-06 26.6 6.8 4.2e-06 26.6 6.8 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXX73910.1 - 1e-05 25.7 17.9 2.9e-05 24.3 5.8 3.0 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 KXX73910.1 - 2.9e-05 23.8 15.5 0.00067 19.4 6.9 2.9 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXX73910.1 - 3.7e-05 23.2 8.6 3.7e-05 23.2 8.6 2.9 1 1 2 3 3 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 KXX73910.1 - 0.00036 20.3 20.4 0.0012 18.7 7.1 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 KXX73910.1 - 0.00094 19.0 3.1 0.14 12.1 0.0 3.0 3 0 0 3 3 3 2 Rad50 zinc hook motif Prok-RING_4 PF14447.6 KXX73910.1 - 0.0015 18.4 19.0 0.0015 18.3 3.2 3.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 FYVE PF01363.21 KXX73910.1 - 0.0032 17.6 13.4 0.012 15.7 8.1 2.9 2 1 1 3 3 3 2 FYVE zinc finger zf-C3HC4_4 PF15227.6 KXX73910.1 - 0.0038 17.4 16.0 0.0043 17.2 7.1 3.0 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-TFIIIC PF12660.7 KXX73910.1 - 0.016 15.2 4.5 0.1 12.5 0.9 2.4 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex zf-C3HC4_5 PF17121.5 KXX73910.1 - 0.026 14.4 4.6 0.059 13.3 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4554 PF15091.6 KXX73910.1 - 0.38 9.6 2.8 0.14 11.0 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) zinc-ribbons_6 PF07191.12 KXX73910.1 - 1.2 9.2 16.5 5 7.2 0.6 3.6 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 KXX73910.1 - 3.7 7.7 18.1 4.9 7.3 10.0 3.4 2 1 0 2 2 2 0 Double zinc ribbon Peptidase_M28 PF04389.17 KXX73912.1 - 3.9e-37 127.9 0.0 4.9e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Zn_clus PF00172.18 KXX73913.1 - 3.4e-08 33.5 8.9 6.6e-08 32.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX73913.1 - 1.4e-05 24.1 0.0 8e-05 21.6 0.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Mito_carr PF00153.27 KXX73914.1 - 3.5e-45 151.9 0.2 8.5e-14 51.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidoligase_2 PF12224.8 KXX73916.1 - 2e-16 60.4 0.0 3.8e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 Putative amidoligase enzyme Dynamin_N PF00350.23 KXX73917.1 - 6.5e-31 107.6 0.0 1.1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXX73917.1 - 2.2e-18 66.5 0.0 2.5e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KXX73917.1 - 3e-05 24.1 0.1 0.00092 19.3 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX73917.1 - 0.047 13.2 0.0 2 7.9 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Phage_tail_X PF05489.12 KXX73917.1 - 0.053 13.2 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Phage Tail Protein X GED PF02212.18 KXX73917.1 - 0.055 13.6 0.8 0.14 12.3 0.2 2.0 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_21 PF13304.6 KXX73917.1 - 0.085 12.7 1.3 0.37 10.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KXX73917.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ceramidase PF05875.12 KXX73918.1 - 0.067 12.6 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Ceramidase Ribonuc_L-PSP PF01042.21 KXX73919.1 - 8.5e-10 38.7 0.0 1.2e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP ZapB PF06005.12 KXX73920.1 - 0.011 16.2 8.4 0.011 16.2 8.4 2.0 1 1 1 2 2 2 0 Cell division protein ZapB HAUS-augmin3 PF14932.6 KXX73920.1 - 0.028 14.0 10.0 0.045 13.3 10.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Mei4 PF13971.6 KXX73920.1 - 0.18 11.3 2.5 0.25 10.8 2.5 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Nop25 PF09805.9 KXX73920.1 - 0.23 11.9 8.3 0.48 10.9 8.3 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) APG6_N PF17675.1 KXX73920.1 - 0.29 11.7 11.8 0.52 10.8 11.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 KXX73920.1 - 0.69 9.7 8.0 1.1 9.0 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Apt1 PF10351.9 KXX73920.1 - 0.81 8.5 7.1 1.2 7.9 7.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain UPF0242 PF06785.11 KXX73920.1 - 1.7 8.7 11.4 2.8 8.0 11.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tox-HNH-EHHH PF15657.6 KXX73920.1 - 2 8.8 5.9 1.7 9.1 0.1 2.6 2 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins TMA7 PF09072.10 KXX73920.1 - 2.3 9.1 5.7 2.3 9.1 3.8 2.1 2 1 0 2 2 2 0 Translation machinery associated TMA7 AA_permease PF00324.21 KXX73921.1 - 6.7e-120 400.9 42.7 8e-120 400.6 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX73921.1 - 9.7e-28 97.1 46.1 1.3e-27 96.8 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease Ldh_1_N PF00056.23 KXX73922.1 - 3.7e-42 143.8 0.8 7.2e-42 142.8 0.8 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXX73922.1 - 1.2e-20 74.2 0.0 2.1e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KXX73922.1 - 6.1e-06 25.9 2.3 0.011 15.3 0.1 3.1 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase ThiF PF00899.21 KXX73922.1 - 8.5e-05 22.0 0.2 0.00017 21.1 0.2 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 KXX73922.1 - 0.00039 20.8 1.3 0.00062 20.2 0.4 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KXX73922.1 - 0.00062 19.4 0.2 0.0012 18.4 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KXX73922.1 - 0.0015 18.2 3.6 0.0015 18.2 3.6 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX73922.1 - 0.0015 17.8 1.1 0.0065 15.7 0.2 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXX73922.1 - 0.0028 17.6 1.2 0.0043 16.9 0.4 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXX73922.1 - 0.0047 17.0 0.9 0.023 14.8 0.2 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KXX73922.1 - 0.0082 15.5 1.0 0.015 14.6 1.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KXX73922.1 - 0.02 14.5 0.9 0.05 13.3 0.5 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KXX73922.1 - 0.039 14.2 0.8 0.12 12.7 0.5 1.9 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 KXX73922.1 - 0.077 13.2 0.6 0.21 11.9 0.6 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Porin_OmpL1 PF11389.8 KXX73922.1 - 0.092 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 F420_oxidored PF03807.17 KXX73922.1 - 0.11 13.1 2.7 0.19 12.3 1.4 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KXX73922.1 - 0.33 11.2 2.5 0.65 10.3 0.4 2.3 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain CFEM PF05730.11 KXX73923.1 - 0.0044 17.1 2.6 0.0072 16.4 2.6 1.4 1 0 0 1 1 1 1 CFEM domain Glycophorin_A PF01102.18 KXX73923.1 - 0.063 13.5 0.4 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 Glycophorin A GCS PF03074.16 KXX73924.1 - 3.4e-174 579.4 0.0 4.8e-174 578.9 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase Glyco_hydro_72 PF03198.14 KXX73925.1 - 1e-71 241.8 2.2 1.9e-71 240.9 2.2 1.4 1 0 0 1 1 1 1 Glucanosyltransferase FCH PF00611.23 KXX73925.1 - 4.3e-24 84.6 0.1 4.3e-24 84.6 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KXX73925.1 - 2.1e-20 72.3 0.2 2e-13 50.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KXX73925.1 - 6.6e-15 54.7 5.6 6.6e-15 54.7 5.6 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 KXX73925.1 - 5e-11 42.0 0.0 4.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 KXX73925.1 - 0.00075 19.7 0.1 0.23 11.8 0.0 2.7 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_2 PF07653.17 KXX73925.1 - 0.0017 18.0 0.0 0.94 9.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cellulase PF00150.18 KXX73925.1 - 0.0054 16.2 0.4 0.058 12.8 0.4 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) C1_2 PF03107.16 KXX73925.1 - 0.013 15.8 4.8 0.026 14.8 4.8 1.5 1 0 0 1 1 1 0 C1 domain HypA PF01155.19 KXX73925.1 - 0.059 13.4 1.5 0.27 11.3 1.5 2.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LETM1 PF07766.13 KXX73925.1 - 0.059 12.7 9.3 0.25 10.6 0.6 2.4 2 0 0 2 2 2 0 LETM1-like protein SH3_10 PF17902.1 KXX73925.1 - 0.081 13.0 0.2 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 SH3 domain Allexi_40kDa PF05549.11 KXX73925.1 - 0.26 10.8 2.8 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein 7TM_GPCR_Sri PF10327.9 KXX73925.1 - 0.27 10.4 0.1 0.44 9.7 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri GATA PF00320.27 KXX73926.1 - 4.2e-16 58.2 3.5 7.5e-16 57.5 3.5 1.4 1 0 0 1 1 1 1 GATA zinc finger DEAD PF00270.29 KXX73927.1 - 1.9e-33 115.7 0.2 1e-32 113.3 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX73927.1 - 2.1e-24 86.0 0.0 7.8e-24 84.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX73927.1 - 9.8e-06 25.7 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXX73927.1 - 0.00025 20.8 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 KXX73927.1 - 0.035 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KXX73927.1 - 0.041 14.2 1.8 2.7 8.3 1.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXX73927.1 - 0.15 12.4 0.0 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain GCFC PF07842.12 KXX73928.1 - 1.6e-79 267.4 2.6 1.6e-79 267.4 0.5 1.9 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 KXX73928.1 - 7.8e-14 51.9 9.7 7.8e-14 51.9 9.7 3.3 2 1 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.23 KXX73928.1 - 4.4e-13 48.9 4.2 4.4e-13 48.9 4.2 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXX73928.1 - 1.1e-07 31.9 2.2 1.1e-07 31.9 2.2 3.2 4 0 0 4 4 4 1 G-patch domain FUSC PF04632.12 KXX73928.1 - 0.0081 14.8 2.2 0.015 13.8 2.2 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein family Epimerase PF01370.21 KXX73929.1 - 6.1e-14 52.1 0.9 1.6e-13 50.7 0.9 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX73929.1 - 4.5e-10 39.7 0.1 1.9e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXX73929.1 - 9.8e-07 28.0 0.0 2.1e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXX73929.1 - 5.7e-06 26.0 0.1 1.1e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXX73929.1 - 1.9e-05 24.2 0.1 0.0081 15.6 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXX73929.1 - 0.00058 19.1 0.0 0.00085 18.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXX73929.1 - 0.00064 19.0 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXX73929.1 - 0.0057 16.2 0.1 0.0095 15.5 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 KXX73929.1 - 0.053 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 KR domain Glyco_trans_4_4 PF13579.6 KXX73929.1 - 1.6 9.1 8.2 0.55 10.6 2.6 2.6 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain adh_short_C2 PF13561.6 KXX73930.1 - 2.1e-56 191.1 0.4 3.1e-56 190.6 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX73930.1 - 2.9e-49 167.2 1.9 4e-49 166.7 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX73930.1 - 1.2e-15 57.8 0.3 1.7e-15 57.4 0.3 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KXX73930.1 - 0.0012 18.8 1.0 0.034 14.1 0.3 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KXX73930.1 - 0.017 14.6 0.6 0.075 12.5 0.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1372 PF07116.11 KXX73930.1 - 0.051 13.8 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) THF_DHG_CYH_C PF02882.19 KXX73930.1 - 0.079 12.3 0.1 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pectinesterase PF01095.19 KXX73931.1 - 3.8e-50 170.3 2.0 5e-50 169.9 2.0 1.0 1 0 0 1 1 1 1 Pectinesterase Lyase_aromatic PF00221.19 KXX73932.1 - 2.2e-153 511.3 8.5 3e-153 510.8 8.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase EF-hand_1 PF00036.32 KXX73933.1 - 6.6e-36 119.2 11.4 1e-08 34.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXX73933.1 - 1.1e-32 112.2 3.9 4.1e-16 59.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXX73933.1 - 3.2e-31 104.6 8.6 1.4e-08 34.0 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXX73933.1 - 6.2e-27 93.2 10.2 2.4e-13 49.7 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXX73933.1 - 2.6e-25 86.8 12.3 3.2e-07 29.5 0.1 4.7 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXX73933.1 - 4e-16 59.1 0.2 6.2e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXX73933.1 - 7.8e-11 41.9 1.4 7.2e-05 22.7 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KXX73933.1 - 2.5e-08 34.7 0.0 0.001 19.9 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KXX73933.1 - 1.1e-07 32.2 0.3 0.017 15.4 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KXX73933.1 - 0.00021 21.2 1.2 0.23 11.4 0.0 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 KXX73933.1 - 0.0003 20.9 6.1 0.16 12.2 0.7 3.4 2 2 1 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KXX73933.1 - 0.0026 16.4 0.0 0.97 7.9 0.0 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 KXX73933.1 - 0.0032 17.8 0.3 3 8.2 0.0 2.5 1 1 2 3 3 3 2 EF-hand domain SurA_N_3 PF13624.6 KXX73933.1 - 0.0059 16.4 0.2 0.48 10.2 0.0 2.1 1 1 1 2 2 2 1 SurA N-terminal domain Phage_Arf PF17585.2 KXX73933.1 - 0.02 14.8 0.2 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Accessory recombination function protein Toprim_2 PF13155.6 KXX73933.1 - 0.025 15.0 0.4 0.89 10.0 0.0 2.2 2 1 0 2 2 2 0 Toprim-like EFhand_Ca_insen PF08726.10 KXX73933.1 - 0.032 14.3 0.1 0.088 12.9 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand SurA_N_2 PF13623.6 KXX73933.1 - 0.032 14.1 0.3 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 SurA N-terminal domain Caleosin PF05042.13 KXX73933.1 - 0.047 13.6 0.9 13 5.7 0.0 3.4 1 1 2 4 4 4 0 Caleosin related protein Toprim PF01751.22 KXX73933.1 - 0.064 13.5 0.1 0.38 11.0 0.0 2.0 1 1 0 2 2 2 0 Toprim domain Toprim_4 PF13662.6 KXX73933.1 - 0.12 12.9 0.3 1.8 9.1 0.0 2.3 2 1 0 2 2 2 0 Toprim domain PMBR PF09373.10 KXX73933.1 - 0.16 12.2 0.0 19 5.7 0.0 3.0 2 1 0 2 2 2 0 Pseudomurein-binding repeat HET PF06985.11 KXX73934.1 - 0.00044 20.6 0.0 0.00048 20.5 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1688 PF07958.11 KXX73935.1 - 3.3e-177 589.4 0.0 3.9e-177 589.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) GIY-YIG PF01541.24 KXX73937.1 - 1.1e-12 48.0 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 KXX73937.1 - 0.022 15.0 0.4 0.038 14.3 0.4 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KXX73937.1 - 0.026 14.7 0.7 0.044 13.9 0.7 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain T5orf172 PF10544.9 KXX73937.1 - 0.042 14.4 0.0 0.1 13.2 0.0 1.7 2 0 0 2 2 2 0 T5orf172 domain FANCL_C PF11793.8 KXX73937.1 - 0.077 13.2 1.3 0.13 12.5 1.3 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KXX73937.1 - 0.82 9.6 3.1 1.6 8.7 3.1 1.5 1 1 0 1 1 1 0 PHD-finger PLU-1 PF08429.11 KXX73938.1 - 2.2e-118 395.3 14.2 2.5e-115 385.3 11.7 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KXX73938.1 - 5.8e-44 149.2 0.2 1.3e-43 148.0 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KXX73938.1 - 8.5e-22 77.6 0.1 2.3e-21 76.3 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KXX73938.1 - 2.4e-17 62.5 29.1 8.6e-10 38.4 5.9 3.7 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 KXX73938.1 - 1.9e-14 53.3 1.3 4.6e-14 52.1 1.3 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KXX73938.1 - 5e-10 39.6 5.9 1.3e-09 38.3 5.9 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger C1_1 PF00130.22 KXX73938.1 - 0.0027 17.6 10.2 0.23 11.4 0.5 3.0 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Chloroplast_duf PF14476.6 KXX73938.1 - 0.51 9.3 2.1 0.91 8.4 0.1 2.0 2 0 0 2 2 2 0 Petal formation-expressed PHD_4 PF16866.5 KXX73938.1 - 0.54 10.4 19.5 0.57 10.3 5.6 3.4 2 1 1 3 3 3 0 PHD-finger zf-PHD-like PF15446.6 KXX73938.1 - 1.1 8.8 9.4 4 7.0 1.8 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Sugar_tr PF00083.24 KXX73939.1 - 3.6e-30 105.2 19.9 2.8e-27 95.7 19.9 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX73939.1 - 1.8e-29 102.8 24.5 1.8e-29 102.8 24.5 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily LacY_symp PF01306.19 KXX73939.1 - 0.00063 18.6 9.4 0.00063 18.6 9.4 1.8 2 1 0 2 2 2 1 LacY proton/sugar symporter Peptidase_A8 PF01252.18 KXX73939.1 - 1.2 9.3 6.6 0.15 12.3 0.8 2.4 2 1 0 2 2 2 0 Signal peptidase (SPase) II DUF3449 PF11931.8 KXX73940.1 - 3.8e-73 245.2 1.5 1.3e-72 243.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KXX73940.1 - 1e-25 90.1 1.7 1.1e-25 90.0 0.3 1.8 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KXX73940.1 - 2.2e-13 49.8 0.3 2.2e-13 49.8 0.3 2.4 3 0 0 3 3 3 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 KXX73940.1 - 5.6e-11 42.4 3.0 1.4e-08 34.8 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX73940.1 - 3.6e-10 39.9 1.2 4.4e-08 33.2 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXX73940.1 - 8.8e-05 22.8 0.2 0.062 13.6 0.0 3.6 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) PRP9_N PF16958.5 KXX73940.1 - 0.00044 20.3 9.8 0.066 13.2 0.2 3.0 2 1 1 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C4H2 PF10146.9 KXX73940.1 - 0.02 15.2 0.2 0.052 13.9 0.2 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein zf-DBF PF07535.12 KXX73940.1 - 0.023 14.8 0.3 0.023 14.8 0.3 2.7 2 1 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.6 KXX73940.1 - 0.058 14.3 1.0 15 6.8 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DEAD PF00270.29 KXX73941.1 - 6.1e-43 146.6 0.2 1e-42 145.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX73941.1 - 2.6e-33 114.7 0.0 9.6e-33 112.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXX73941.1 - 0.00043 20.0 0.1 0.00065 19.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXX73941.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXX73941.1 - 0.0016 18.8 0.1 0.012 16.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain DUF5393 PF17371.2 KXX73941.1 - 0.052 11.7 0.1 0.083 11.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Flavi_DEAD PF07652.14 KXX73941.1 - 0.057 13.4 0.2 0.19 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 KXX73941.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KXX73941.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KXX73941.1 - 0.15 12.4 0.9 0.67 10.2 0.9 2.0 1 1 0 1 1 1 0 AAA domain DUF373 PF04123.13 KXX73942.1 - 2.2 7.7 4.4 1.7 8.0 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Pkinase PF00069.25 KXX73943.1 - 5.7e-32 111.1 0.0 8.8e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73943.1 - 6.3e-20 71.5 0.0 9.2e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXX73943.1 - 0.046 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fringe PF02434.16 KXX73944.1 - 1.3e-07 31.3 0.6 1.3e-06 28.1 0.6 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KXX73944.1 - 0.0015 18.4 3.4 0.0043 16.9 3.4 1.7 1 0 0 1 1 1 1 PAN domain Peptidase_M28 PF04389.17 KXX73945.1 - 2.2e-39 135.2 0.0 4.5e-39 134.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KXX73945.1 - 1e-10 41.5 0.0 3e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXX73945.1 - 1.1e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Hemerythrin PF01814.23 KXX73946.1 - 1e-13 52.1 2.0 1.5e-13 51.5 2.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CENP-Q PF13094.6 KXX73946.1 - 0.11 12.7 1.8 0.18 12.0 1.8 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CTK3_C PF12350.8 KXX73946.1 - 0.53 10.5 4.8 1.9 8.7 0.3 2.2 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus p450 PF00067.22 KXX73947.1 - 9.5e-51 173.0 0.0 1.3e-50 172.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2196 PF09962.9 KXX73948.1 - 1.6e-22 79.3 2.2 2.4e-22 78.7 2.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Nop PF01798.18 KXX73950.1 - 3.6e-74 249.1 0.0 6.5e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KXX73950.1 - 3.1e-44 150.8 3.7 3.2e-44 150.7 1.7 2.1 2 0 0 2 2 2 1 Prp31 C terminal domain TPR_14 PF13428.6 KXX73952.1 - 7.6e-27 91.7 30.8 2.2e-05 24.9 0.2 12.6 8 3 7 15 15 15 5 Tetratricopeptide repeat HAT PF02184.16 KXX73952.1 - 9.4e-24 83.1 60.7 5.5e-10 39.0 1.4 12.6 13 0 0 13 13 13 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 KXX73952.1 - 3.9e-23 81.7 1.1 8.2e-08 32.7 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 KXX73952.1 - 1.4e-18 68.0 10.9 7.4e-06 26.2 0.1 6.7 3 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 KXX73952.1 - 2.9e-11 43.1 9.8 0.0018 17.5 1.3 5.9 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXX73952.1 - 1e-07 31.6 0.1 0.56 10.6 0.0 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX73952.1 - 4.5e-07 30.4 14.4 0.057 14.1 0.1 8.0 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXX73952.1 - 1.3e-06 28.6 16.8 0.62 10.8 0.0 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXX73952.1 - 4.4e-06 26.8 2.0 1 9.6 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXX73952.1 - 5.3e-06 26.4 3.7 0.72 10.0 0.0 5.6 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 KXX73952.1 - 2.3e-05 24.4 11.6 0.2 12.1 0.0 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXX73952.1 - 8.2e-05 22.4 23.0 0.0081 16.2 0.1 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat YfiO PF13525.6 KXX73952.1 - 0.0016 18.2 0.0 0.017 14.9 0.0 2.6 1 1 1 2 2 2 1 Outer membrane lipoprotein U3_assoc_6 PF08640.11 KXX73952.1 - 0.003 17.6 16.3 0.2 11.7 1.3 6.3 4 2 2 6 6 6 2 U3 small nucleolar RNA-associated protein 6 ANAPC3 PF12895.7 KXX73952.1 - 0.0075 16.5 1.4 1.3 9.3 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KXX73952.1 - 0.0098 16.2 13.6 6 7.2 0.0 7.4 9 0 0 9 9 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KXX73952.1 - 0.042 13.0 31.3 0.67 9.0 0.6 5.9 3 3 2 5 5 5 0 NRDE-2, necessary for RNA interference QIL1 PF15884.5 KXX73952.1 - 0.047 14.3 0.1 3.9 8.2 0.0 3.8 5 0 0 5 5 3 0 MICOS complex subunit MIC13, QIL1 TPR_1 PF00515.28 KXX73952.1 - 0.17 11.8 4.9 3.6 7.6 0.0 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX73952.1 - 5.7 6.9 21.7 14 5.7 0.2 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Glyco_tranf_2_3 PF13641.6 KXX73954.1 - 2.3e-10 40.7 0.1 4.9e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXX73954.1 - 6e-09 36.1 9.2 2.5e-08 34.1 9.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KXX73954.1 - 4.2e-08 32.9 0.1 8.6e-08 31.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KXX73954.1 - 1.4e-05 23.9 0.5 0.00028 19.7 0.5 2.3 1 1 0 1 1 1 1 Chitin synthase HRXXH PF13933.6 KXX73955.1 - 5.2e-69 232.5 0.2 5.7e-69 232.4 0.2 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KXX73955.1 - 4e-05 24.2 0.1 5.3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF423 PF04241.15 KXX73956.1 - 4.2e-19 68.6 3.1 1e-17 64.1 3.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF423) Zn_clus PF00172.18 KXX73957.1 - 1.5e-08 34.6 8.5 2.4e-08 34.0 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX73957.1 - 1.4e-07 30.7 6.3 2.5e-07 29.8 5.3 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_6 PF01341.17 KXX73958.1 - 3.1e-104 349.0 0.0 4e-104 348.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 GTP_cyclohydro2 PF00925.20 KXX73959.1 - 1.9e-60 203.1 0.0 2.7e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II YL1 PF05764.13 KXX73960.1 - 0.0011 19.2 10.7 0.0011 19.2 10.7 5.6 4 2 0 4 4 4 1 YL1 nuclear protein Nop14 PF04147.12 KXX73960.1 - 8.1 4.5 36.9 1.7 6.7 14.0 2.5 2 0 0 2 2 2 0 Nop14-like family Ribosomal_S24e PF01282.19 KXX73961.1 - 1.3e-36 124.4 0.1 2.3e-36 123.6 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e Abhydrolase_4 PF08386.10 KXX73962.1 - 4.2e-23 81.4 0.0 8.2e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXX73962.1 - 3.6e-19 69.4 0.1 5.4e-15 55.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold HEAT_PBS PF03130.16 KXX73962.1 - 0.12 13.1 0.1 1.5 9.7 0.0 2.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat SDF PF00375.18 KXX73963.1 - 5e-86 289.2 33.3 6.2e-86 288.8 33.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.6 KXX73963.1 - 0.016 15.0 0.1 0.13 12.2 0.1 2.6 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase FAM76 PF16046.5 KXX73964.1 - 0.98 8.7 2.8 1.6 8.0 2.8 1.2 1 0 0 1 1 1 0 FAM76 protein PGG PF13962.6 KXX73965.1 - 0.16 11.8 0.2 0.27 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function Methyltransf_16 PF10294.9 KXX73966.1 - 3.7e-17 62.6 0.0 6.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KXX73966.1 - 0.00023 21.8 0.1 0.001 19.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXX73966.1 - 0.00032 20.5 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXX73966.1 - 0.00098 19.0 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXX73966.1 - 0.0033 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXX73966.1 - 0.0056 16.5 0.1 0.012 15.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXX73966.1 - 0.0088 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KXX73966.1 - 0.027 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.12 KXX73966.1 - 0.04 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 KXX73966.1 - 0.062 14.0 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Mad3_BUB1_I PF08311.12 KXX73967.1 - 4.6e-44 149.4 0.5 1.3e-43 147.9 0.5 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KXX73967.1 - 1.8e-09 37.6 0.0 1.5e-08 34.7 0.0 2.5 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KXX73967.1 - 5.1e-09 35.9 0.0 2.2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX73967.1 - 0.0077 15.5 0.0 0.037 13.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXX73967.1 - 1.9 8.4 6.0 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family AP_endonuc_2 PF01261.24 KXX73968.1 - 7.1e-33 113.8 0.1 1e-32 113.3 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SNARE_assoc PF09335.11 KXX73970.1 - 5.3e-13 49.5 8.1 5.3e-13 49.5 8.1 2.4 2 1 2 4 4 4 1 SNARE associated Golgi protein DUF1771 PF08590.10 KXX73971.1 - 3.7e-15 56.1 12.1 1e-14 54.6 12.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KXX73971.1 - 5.5e-08 32.6 8.2 1.2e-05 25.1 0.8 3.0 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KXX73971.1 - 1.2e-06 28.7 0.0 6.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.24 KXX73971.1 - 8.3e-06 25.6 3.0 0.0049 16.8 0.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KXX73971.1 - 1.4e-05 25.4 3.8 0.059 13.9 0.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KXX73971.1 - 0.00016 21.4 9.7 0.002 17.9 0.3 3.2 2 1 0 2 2 2 1 CCCH-type zinc finger HBS1_N PF08938.10 KXX73971.1 - 0.0041 17.4 0.1 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 HBS1 N-terminus PAM2 PF07145.15 KXX73971.1 - 0.037 13.7 0.7 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Torus PF16131.5 KXX73971.1 - 0.062 14.0 4.9 1 10.1 0.6 2.5 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KXX73971.1 - 0.49 10.6 2.9 3.4 7.9 2.9 2.0 1 1 0 1 1 1 0 Zinc-finger containing family Cupin_8 PF13621.6 KXX73972.1 - 3.5e-19 69.5 0.0 9.7e-18 64.8 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXX73972.1 - 1.2e-10 41.8 0.0 2.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KXX73972.1 - 0.0012 18.7 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 KXX73972.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein RRM_1 PF00076.22 KXX73973.1 - 4.1e-17 61.8 0.0 9.2e-17 60.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXX73973.1 - 0.00025 21.5 18.2 0.00025 21.5 18.2 3.9 3 1 1 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 F-box-like PF12937.7 KXX73974.1 - 9.2e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.9 KXX73974.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) F-box_4 PF15966.5 KXX73974.1 - 0.24 11.3 0.1 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 F-box DEAD PF00270.29 KXX73976.1 - 3.1e-45 154.1 1.3 5.1e-45 153.4 1.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX73976.1 - 8e-32 109.9 0.3 8.8e-31 106.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX73976.1 - 3e-06 27.4 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXX73976.1 - 0.0004 20.1 0.1 0.00081 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX73976.1 - 0.0025 18.2 1.2 0.013 15.8 0.4 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXX73976.1 - 0.0088 16.3 0.3 0.031 14.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain IL17R_D_N PF16742.5 KXX73976.1 - 0.016 15.2 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CMS1 PF14617.6 KXX73976.1 - 0.045 13.1 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 KXX73976.1 - 0.089 12.3 0.1 0.14 11.7 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain fragilysinNterm PF16376.5 KXX73976.1 - 0.094 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 KXX73976.1 - 0.1 12.6 0.1 0.46 10.4 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.25 KXX73976.1 - 0.11 11.8 0.2 0.48 9.7 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.14 KXX73976.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Helicase Stb3 PF10330.9 KXX73978.1 - 3.7e-37 126.2 0.0 5.7e-37 125.6 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.20 KXX73979.1 - 5.9e-107 358.2 0.0 2.9e-101 339.5 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KXX73979.1 - 7.6e-20 71.1 0.0 1.5e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF2830 PF11125.8 KXX73980.1 - 1.5 8.8 3.9 0.78 9.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) DUF4149 PF13664.6 KXX73981.1 - 2.8e-24 85.4 2.3 2.8e-24 85.4 2.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) ECF_trnsprt PF12822.7 KXX73981.1 - 1.6 8.8 9.4 0.36 10.9 5.5 1.7 2 1 0 2 2 2 0 ECF transporter, substrate-specific component HET PF06985.11 KXX73982.1 - 2.6e-30 105.7 0.0 4.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3875 PF12991.7 KXX73982.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) Ku PF02735.16 KXX73983.1 - 4e-34 118.1 0.0 6.7e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KXX73983.1 - 1.5e-33 115.5 0.0 3.4e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KXX73983.1 - 6.6e-16 58.7 0.0 1.1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KXX73983.1 - 3e-05 24.3 0.1 8e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 KXX73983.1 - 0.064 14.0 1.3 0.2 12.4 0.0 2.5 3 1 0 3 3 3 0 Ku70/Ku80 C-terminal arm DUF2408 PF10303.9 KXX73983.1 - 0.13 12.8 0.5 0.36 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF1295 PF06966.12 KXX73984.1 - 1.9e-37 129.0 7.9 2.5e-37 128.6 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Pam16 PF03656.13 KXX73985.1 - 7.3e-06 26.0 0.0 8.8e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KXX73985.1 - 2.7e-05 24.2 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KXX73985.1 - 0.0025 17.4 0.8 0.0025 17.4 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3918) DUF374 PF04028.13 KXX73986.1 - 0.097 12.2 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Abhydrolase_6 PF12697.7 KXX73987.1 - 2.7e-08 34.7 0.0 5.3e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX73987.1 - 0.0012 18.2 0.1 0.01 15.1 0.1 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX73987.1 - 0.036 13.7 0.1 0.16 11.6 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold eRF1_1 PF03463.15 KXX73988.1 - 1.1e-32 112.7 0.1 1.8e-32 112.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KXX73988.1 - 3.5e-20 72.7 0.1 5.6e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXX73988.1 - 2e-18 66.9 0.1 4.9e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 3 Methyltransf_25 PF13649.6 KXX73989.1 - 8.2e-21 74.5 0.0 1.3e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX73989.1 - 1.3e-18 67.4 0.0 2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX73989.1 - 3e-12 47.1 0.0 5.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX73989.1 - 1.7e-10 41.0 0.0 2.9e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX73989.1 - 1.2e-09 38.1 0.0 1.5e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 KXX73989.1 - 1.9e-06 27.6 0.0 2.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 KXX73989.1 - 3.1e-06 26.7 0.0 5.7e-06 25.8 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KXX73989.1 - 6.8e-06 25.8 0.0 8.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KXX73989.1 - 2e-05 24.2 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXX73989.1 - 2.1e-05 23.9 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KXX73989.1 - 0.00043 19.7 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 KXX73989.1 - 0.00065 19.2 0.0 0.021 14.3 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain RrnaAD PF00398.20 KXX73989.1 - 0.0015 17.6 0.0 0.002 17.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 KXX73989.1 - 0.0019 16.8 0.0 0.0024 16.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KXX73989.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXX73989.1 - 0.19 11.1 0.1 0.31 10.4 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4246 PF14033.6 KXX73990.1 - 4.5e-160 533.7 0.2 5.4e-160 533.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) uDENN PF03456.18 KXX73990.1 - 0.082 13.7 0.0 0.8 10.5 0.0 2.6 2 0 0 2 2 2 0 uDENN domain WSC PF01822.19 KXX73991.1 - 2.5e-38 130.1 21.1 2.8e-19 69.1 6.3 2.1 2 0 0 2 2 2 2 WSC domain Thioredoxin PF00085.20 KXX73992.1 - 1.1e-21 76.7 0.0 1.7e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXX73992.1 - 9.7e-06 25.8 0.0 3.9e-05 23.9 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 KXX73992.1 - 1.3e-05 24.7 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXX73992.1 - 1.4e-05 25.0 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KXX73992.1 - 3.4e-05 24.3 0.1 0.00077 19.9 0.1 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.10 KXX73992.1 - 0.00048 19.9 0.0 0.0025 17.5 0.1 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 KXX73992.1 - 0.014 15.5 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KXX73992.1 - 0.014 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 KXX73992.1 - 0.015 15.4 0.0 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin domain DIM1 PF02966.16 KXX73992.1 - 0.041 13.7 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Glutaredoxin PF00462.24 KXX73992.1 - 0.075 13.3 0.1 0.15 12.3 0.1 1.6 1 1 0 1 1 1 0 Glutaredoxin HyaE PF07449.11 KXX73992.1 - 0.15 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE BCS1_N PF08740.11 KXX73993.1 - 2.9e-36 125.2 2.6 2.9e-36 125.2 2.6 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KXX73993.1 - 3.9e-19 69.4 0.1 1.1e-17 64.7 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX73993.1 - 5.7e-05 22.9 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX73993.1 - 0.0028 18.0 0.9 0.015 15.7 0.1 2.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXX73993.1 - 0.0048 16.9 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXX73993.1 - 0.0061 15.7 0.0 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXX73993.1 - 0.0076 16.8 2.4 0.025 15.1 0.0 2.7 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXX73993.1 - 0.012 15.3 0.0 0.04 13.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KXX73993.1 - 0.014 15.0 0.0 0.06 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXX73993.1 - 0.034 13.5 1.9 0.1 11.9 0.0 2.2 2 0 0 2 2 2 0 KaiC Tnp_22_trimer PF17489.2 KXX73993.1 - 0.036 14.0 0.9 0.13 12.2 0.9 2.0 1 0 0 1 1 1 0 L1 transposable element trimerization domain AAA_33 PF13671.6 KXX73993.1 - 0.05 13.8 0.2 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain CarD_CdnL_TRCF PF02559.16 KXX73993.1 - 0.11 13.2 4.6 0.27 12.0 4.6 1.6 1 0 0 1 1 1 0 CarD-like/TRCF domain AAA_22 PF13401.6 KXX73993.1 - 0.15 12.4 0.2 0.78 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXX73993.1 - 0.22 11.3 10.6 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Orn_Arg_deC_N PF02784.16 KXX73993.1 - 0.48 9.8 2.0 0.75 9.1 2.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain XRN_M PF17846.1 KXX73993.1 - 0.63 8.9 3.2 1.1 8.1 3.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain AAA_23 PF13476.6 KXX73993.1 - 4.8 7.6 8.8 55 4.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KXX73993.1 - 6.4 5.3 13.5 2.3 6.8 0.2 2.1 2 0 0 2 2 2 0 AAA domain Spt5_N PF11942.8 KXX73993.1 - 9.5 7.3 20.6 9.8 7.2 11.5 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Amidoligase_2 PF12224.8 KXX73994.1 - 2.4e-17 63.5 0.0 9.8e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme HGTP_anticodon PF03129.20 KXX73994.1 - 0.044 13.9 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Anticodon binding domain WD40 PF00400.32 KXX73995.1 - 7e-30 102.6 5.5 2.2e-06 28.3 0.0 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX73995.1 - 3.1e-06 27.4 0.1 0.26 11.6 0.0 4.1 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4875 PF16175.5 KXX73995.1 - 0.0064 16.6 0.4 1.2 9.3 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4875) Ge1_WD40 PF16529.5 KXX73995.1 - 0.015 14.3 0.1 1 8.3 0.0 3.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXX73995.1 - 0.033 14.1 0.1 33 4.6 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KXX73995.1 - 0.053 12.2 0.8 3.4 6.2 0.2 3.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Zn_Tnp_IS1595 PF12760.7 KXX73995.1 - 0.36 10.8 2.3 0.79 9.8 2.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Aldo_ket_red PF00248.21 KXX73996.1 - 4.3e-36 124.6 0.0 1.9e-26 93.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Dabb PF07876.12 KXX73997.1 - 1.3e-25 89.8 0.0 1.6e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF2461 PF09365.10 KXX73997.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) SOG2 PF10428.9 KXX73999.1 - 0.011 14.9 9.1 0.014 14.6 9.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mito_fiss_reg PF05308.11 KXX73999.1 - 0.035 14.2 13.9 0.053 13.6 13.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator ECH_1 PF00378.20 KXX74000.1 - 2.4e-39 135.2 0.2 5.1e-39 134.1 0.2 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX74000.1 - 6.6e-34 117.9 0.1 2.5e-32 112.7 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PEP_hydrolase PF09370.10 KXX74000.1 - 0.0021 17.3 0.1 0.0039 16.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like AMP-binding PF00501.28 KXX74001.1 - 2.2e-84 283.5 0.0 2.9e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX74001.1 - 1.3e-12 48.5 0.1 2.9e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tfb5 PF06331.12 KXX74002.1 - 2.3e-26 91.6 1.1 2.5e-26 91.4 1.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 NAD_binding_5 PF07994.12 KXX74003.1 - 4e-146 486.5 0.0 5.2e-146 486.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KXX74003.1 - 2.4e-46 156.5 0.5 5e-46 155.4 0.5 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase MFS_1 PF07690.16 KXX74004.1 - 7.3e-33 113.9 58.9 7e-30 104.1 39.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74004.1 - 2.5e-21 76.1 22.4 1e-17 64.2 7.4 2.4 2 1 1 3 3 3 3 Sugar (and other) transporter Pectate_lyase_3 PF12708.7 KXX74005.1 - 1e-48 166.0 6.2 9.6e-43 146.5 1.3 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.6 KXX74005.1 - 6.2e-06 26.1 1.8 8.4e-05 22.5 1.9 2.4 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 KXX74005.1 - 0.00046 19.5 0.4 0.00086 18.6 0.4 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Adeno_E1B_55K PF01696.17 KXX74005.1 - 0.21 10.2 0.7 0.34 9.6 0.7 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen DnaJ PF00226.31 KXX74006.1 - 2.1e-11 43.8 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain NIL PF09383.10 KXX74006.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 NIL domain CRISPR_Cse2 PF09485.10 KXX74006.1 - 0.047 14.2 0.0 0.16 12.4 0.0 1.9 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Ran_BP1 PF00638.18 KXX74007.1 - 6.1e-13 49.1 0.0 5e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 RanBP1 domain Nucleoporin_FG PF13634.6 KXX74007.1 - 7.4e-06 26.7 56.5 0.00013 22.7 20.1 10.9 2 1 7 9 9 9 5 Nucleoporin FG repeat region SCP2 PF02036.17 KXX74008.1 - 3.2e-24 85.3 0.6 3.7e-24 85.2 0.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KXX74008.1 - 8.1e-08 32.6 0.2 1e-07 32.3 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KXX74008.1 - 0.0005 20.4 0.1 0.00064 20.1 0.1 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain DUF3397 PF11877.8 KXX74010.1 - 0.019 15.2 0.3 0.019 15.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) BTB PF00651.31 KXX74011.1 - 0.007 16.6 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_23 PF13489.6 KXX74012.1 - 8.1e-19 68.1 0.0 1.1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74012.1 - 2e-16 60.4 0.1 5.6e-15 55.8 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74012.1 - 5.2e-16 59.1 0.0 2.7e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXX74012.1 - 9.5e-14 51.9 0.0 1.1e-12 48.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74012.1 - 1.2e-12 47.9 0.0 2e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXX74012.1 - 9e-05 21.9 0.1 0.1 11.9 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX74012.1 - 0.00064 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KXX74012.1 - 0.0013 17.9 0.0 0.052 12.6 0.0 2.1 2 0 0 2 2 2 1 DREV methyltransferase PrmA PF06325.13 KXX74012.1 - 0.0079 15.6 0.0 0.065 12.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KXX74012.1 - 0.011 15.4 0.0 0.6 9.7 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) RrnaAD PF00398.20 KXX74012.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 KXX74012.1 - 0.018 14.5 0.0 0.038 13.4 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 KXX74012.1 - 0.033 13.2 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_16 PF10294.9 KXX74012.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase Glyco_hydro_16 PF00722.21 KXX74013.1 - 9.2e-15 54.6 0.1 3.2e-14 52.8 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXX74013.1 - 3.6e-06 25.7 8.0 0.0017 16.9 0.6 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KXX74013.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Glyco_hydro_10 PF00331.20 KXX74015.1 - 3.9e-97 325.2 0.0 4.6e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KXX74015.1 - 6.9e-13 48.3 11.8 1.8e-12 47.0 11.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain AA_permease PF00324.21 KXX74016.1 - 8.3e-124 413.8 42.1 9.8e-124 413.5 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX74016.1 - 2.8e-31 108.8 46.1 3.8e-31 108.4 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease Egh16-like PF11327.8 KXX74017.1 - 2.2e-65 220.5 7.7 2.9e-65 220.1 7.7 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Loricrin PF15847.5 KXX74017.1 - 0.21 10.6 18.2 0.027 13.6 13.7 1.6 2 0 0 2 2 2 0 Major keratinocyte cell envelope protein adh_short PF00106.25 KXX74020.1 - 2.8e-20 72.6 0.0 1.3e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX74020.1 - 9.1e-16 58.1 0.2 1.5e-13 50.8 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX74020.1 - 2.5e-05 24.2 0.1 4.5e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KXX74021.1 - 3.6e-39 134.8 0.0 4.7e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_6 PF01341.17 KXX74022.1 - 1.3e-101 340.4 0.0 1.6e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KXX74022.1 - 2.9e-14 52.7 16.3 2.9e-14 52.7 16.3 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KXX74022.1 - 0.05 13.9 5.4 0.14 12.5 5.4 1.7 1 0 0 1 1 1 0 Toxin 7 GST_N PF02798.20 KXX74023.1 - 0.012 15.9 0.1 9.7 6.6 0.0 3.0 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain PLDc_2 PF13091.6 KXX74024.1 - 5.4e-22 78.1 0.0 1.1e-13 51.3 0.0 3.4 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXX74024.1 - 2.4e-05 24.3 0.3 0.021 15.0 0.1 2.8 3 0 0 3 3 3 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KXX74024.1 - 0.089 12.0 0.1 2.8 7.0 0.0 3.0 4 0 0 4 4 4 0 Archaeal transcriptional regulator TrmB ThuA PF06283.11 KXX74025.1 - 1.1e-55 189.1 0.0 1.3e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF2183 PF09949.9 KXX74026.1 - 7.6e-33 112.8 0.0 1.6e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Phenol_Hydrox PF02332.18 KXX74026.1 - 0.21 11.1 0.1 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Methane/Phenol/Toluene Hydroxylase UvdE PF03851.14 KXX74027.1 - 1.2e-115 385.5 0.0 1.6e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE PKD_channel PF08016.12 KXX74028.1 - 0.05 12.3 9.7 0.21 10.3 0.9 2.2 2 0 0 2 2 2 0 Polycystin cation channel CysG_dimeriser PF10414.9 KXX74028.1 - 0.94 9.2 3.5 3.5 7.4 3.5 1.9 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Pkr1 PF08636.10 KXX74029.1 - 1.7e-33 114.5 2.2 2.3e-33 114.2 2.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 CBF PF03914.17 KXX74031.1 - 1.7e-33 116.1 0.5 5e-33 114.5 0.0 2.0 2 1 0 2 2 2 1 CBF/Mak21 family DegT_DnrJ_EryC1 PF01041.17 KXX74031.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3201 PF11447.8 KXX74031.1 - 0.12 11.9 1.3 17 5.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3201) Enkurin PF13864.6 KXX74031.1 - 9.3 6.8 8.5 1.4 9.4 1.6 2.7 3 0 0 3 3 3 0 Calmodulin-binding bZIP_1 PF00170.21 KXX74032.1 - 1.1e-10 41.4 15.6 5.9e-10 39.1 11.4 2.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KXX74032.1 - 2e-07 31.5 11.1 5.8e-07 29.9 11.1 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KXX74032.1 - 1.3e-05 25.2 10.9 4.8e-05 23.4 9.9 2.4 2 0 0 2 2 2 1 Basic region leucine zipper PI_PP_I PF18363.1 KXX74032.1 - 0.022 14.9 1.0 0.049 13.8 1.0 1.6 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Exonuc_VII_L PF02601.15 KXX74032.1 - 0.035 13.7 7.0 0.074 12.6 7.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF737 PF05300.11 KXX74032.1 - 0.14 12.5 13.2 0.13 12.6 7.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF1664 PF07889.12 KXX74032.1 - 0.24 11.5 9.7 3.5 7.7 9.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 KXX74032.1 - 0.33 9.5 10.7 0.48 9.0 10.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 KXX74032.1 - 0.38 11.0 22.1 0.032 14.5 17.4 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2205 PF10224.9 KXX74032.1 - 0.42 10.6 7.0 0.38 10.8 5.3 1.9 1 1 0 1 1 1 0 Short coiled-coil protein CCDC-167 PF15188.6 KXX74032.1 - 5.4 7.4 10.9 14 6.1 10.9 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Mt_ATP-synt_B PF05405.14 KXX74033.1 - 9.5e-56 187.9 10.7 1.2e-55 187.6 10.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) LSM PF01423.22 KXX74034.1 - 2e-16 59.4 0.1 2.6e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXX74034.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 KXX74034.1 - 4.4 6.0 9.2 5.3 5.7 9.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MARVEL PF01284.23 KXX74037.1 - 2.5e-07 30.8 17.8 4.1e-07 30.1 17.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3708 PF12501.8 KXX74037.1 - 0.031 14.1 2.6 0.076 12.8 2.6 1.6 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF2070 PF09843.9 KXX74037.1 - 0.69 8.1 13.5 0.83 7.9 13.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Mrx7 PF10906.8 KXX74039.1 - 2e-09 37.6 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 AAA_16 PF13191.6 KXX74040.1 - 1.6e-05 25.4 0.0 5.4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX74040.1 - 0.00029 21.1 0.0 0.0028 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXX74040.1 - 0.00093 19.2 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 KXX74040.1 - 0.052 14.2 3.6 0.12 12.9 0.0 3.4 4 0 0 4 4 4 0 Alpha/beta hydrolase family RNA_helicase PF00910.22 KXX74040.1 - 0.062 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF3089 PF11288.8 KXX74040.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) ABC_tran PF00005.27 KXX74040.1 - 0.13 12.8 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KXX74040.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Glyco_transf_90 PF05686.12 KXX74041.1 - 1.4e-13 50.5 1.5 3.8e-10 39.2 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 90 Arginase PF00491.21 KXX74042.1 - 1.4e-76 257.7 0.2 1.7e-76 257.4 0.2 1.0 1 0 0 1 1 1 1 Arginase family NmrA PF05368.13 KXX74045.1 - 9.1e-10 38.5 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX74045.1 - 0.0022 17.9 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXX74045.1 - 0.18 12.1 0.0 0.73 10.1 0.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXX74045.1 - 0.19 11.8 0.0 17 5.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_23 PF13489.6 KXX74046.1 - 3.9e-19 69.1 0.0 6e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74046.1 - 4.6e-13 49.7 0.0 1.5e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74046.1 - 1.1e-12 48.4 0.0 2.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX74046.1 - 2.3e-09 37.9 0.0 1.4e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74046.1 - 5.7e-06 26.2 0.0 0.098 12.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXX74046.1 - 4e-05 23.1 0.0 0.00035 20.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX74046.1 - 0.007 15.9 0.0 0.18 11.3 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KXX74046.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KXX74046.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_PK PF05891.12 KXX74046.1 - 0.034 13.7 0.1 0.072 12.6 0.0 1.5 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase FtsJ PF01728.19 KXX74046.1 - 0.042 14.0 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KXX74046.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1996 PF09362.10 KXX74047.1 - 7.8e-75 251.9 0.4 9.1e-75 251.6 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DeoC PF01791.9 KXX74048.1 - 2.3e-12 47.0 0.3 3.1e-12 46.6 0.3 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase HET PF06985.11 KXX74049.1 - 1.6e-24 86.9 0.0 8.2e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ammonium_transp PF00909.21 KXX74050.1 - 9.4e-119 396.7 26.0 1.1e-118 396.5 26.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 KXX74050.1 - 1.3 9.1 8.8 1.8 8.6 0.4 3.6 3 0 0 3 3 3 0 Bacteriophage P21 holin S Con-6 PF10346.9 KXX74051.1 - 5.3e-18 64.7 0.6 1.9e-17 62.9 0.7 1.9 2 0 0 2 2 2 1 Conidiation protein 6 Ntox28 PF15605.6 KXX74051.1 - 0.057 13.7 0.2 0.069 13.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial toxin 28 Clr5 PF14420.6 KXX74053.1 - 2.8e-05 24.3 2.1 7.1e-05 22.9 2.1 1.8 1 0 0 1 1 1 1 Clr5 domain FCH PF00611.23 KXX74054.1 - 2.9e-18 65.9 0.0 8.5e-18 64.4 0.0 1.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SHE3 PF17078.5 KXX74054.1 - 0.0021 17.8 0.3 0.0026 17.5 0.3 1.2 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Vps5 PF09325.10 KXX74054.1 - 0.019 14.5 0.6 0.022 14.3 0.6 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DUF4075 PF13294.6 KXX74054.1 - 0.051 13.7 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) DUF922 PF06037.11 KXX74054.1 - 0.068 13.0 0.4 0.099 12.4 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) WD40 PF00400.32 KXX74056.1 - 4.3e-45 150.8 12.4 4.9e-13 49.3 0.3 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74056.1 - 4e-12 46.3 0.0 0.0017 18.6 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX74056.1 - 2.6e-05 23.3 3.3 0.072 12.0 1.1 3.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXX74056.1 - 0.00042 20.2 3.8 1.1 9.3 0.1 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KXX74056.1 - 0.037 13.8 0.1 5.6 6.6 0.0 2.6 1 1 2 3 3 3 0 Lipoprotein LpqB beta-propeller domain SWIM PF04434.17 KXX74056.1 - 0.053 13.2 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 SWIM zinc finger SRP9-21 PF05486.12 KXX74056.1 - 0.19 12.2 0.0 1.6e+02 2.8 0.0 3.2 2 1 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) NACHT_N PF17100.5 KXX74057.1 - 2.4e-73 246.6 0.2 4.5e-73 245.8 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KXX74057.1 - 6.1e-24 84.8 0.0 1.4e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Not1 PF04054.15 KXX74058.1 - 1.6e-119 399.1 1.7 2.9e-119 398.3 0.0 2.4 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KXX74058.1 - 8.7e-91 303.3 2.5 1.8e-90 302.3 2.5 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KXX74058.1 - 1e-49 168.2 0.6 3.3e-49 166.6 0.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KXX74058.1 - 4.9e-43 146.5 0.0 2e-42 144.5 0.0 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KXX74058.1 - 3.5e-39 134.3 0.0 1.3e-38 132.5 0.0 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat PUL PF08324.11 KXX74058.1 - 0.54 9.5 2.5 2.8 7.1 0.0 3.0 3 0 0 3 3 3 0 PUL domain UPF0029 PF01205.19 KXX74059.1 - 1.8e-24 86.1 0.0 3.9e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Methyltransf_23 PF13489.6 KXX74060.1 - 2.7e-17 63.1 0.0 6.3e-17 61.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74060.1 - 0.0038 17.9 0.0 0.65 10.7 0.0 3.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74060.1 - 0.011 16.3 0.0 6.4 7.5 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXX74060.1 - 0.017 15.9 0.0 0.17 12.6 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74060.1 - 0.16 11.7 0.0 0.82 9.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RasGAP PF00616.19 KXX74061.1 - 1.1e-33 116.7 1.2 4.9e-22 78.7 0.0 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KXX74061.1 - 2.3e-08 34.3 0.1 6.5e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mito_carr PF00153.27 KXX74061.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein Cytokin_check_N PF10407.9 KXX74061.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus XRN_M PF17846.1 KXX74062.1 - 4.4e-145 484.0 0.4 2e-144 481.9 0.0 2.1 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KXX74062.1 - 7.9e-100 333.2 0.0 1.1e-99 332.8 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 KXX74062.1 - 0.11 12.4 2.1 0.25 11.2 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.14 KXX74063.1 - 1.2e-113 379.4 0.0 2.8e-113 378.2 0.0 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KXX74063.1 - 1.3e-17 64.3 32.8 1.3e-17 64.3 32.8 3.6 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT PF02985.22 KXX74063.1 - 0.19 12.1 2.3 8.6 6.9 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Spc7 PF08317.11 KXX74063.1 - 0.4 9.5 45.3 0.007 15.3 18.4 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein TFIIA PF03153.13 KXX74063.1 - 0.53 10.2 26.1 0.83 9.6 26.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATG16 PF08614.11 KXX74063.1 - 0.6 10.3 52.8 0.05 13.8 27.5 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 KXX74063.1 - 0.88 8.9 49.5 0.46 9.8 46.7 1.9 1 1 1 2 2 2 0 Tropomyosin DUF3584 PF12128.8 KXX74063.1 - 1.2 6.6 44.1 1.8 6.0 44.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CT_C_D PF02682.16 KXX74063.1 - 3.3 7.4 4.8 9 6.0 4.8 1.8 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Methyltransf_25 PF13649.6 KXX74064.1 - 1.1e-11 45.3 0.0 3.4e-11 43.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 KXX74064.1 - 1.5e-10 41.0 0.0 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXX74064.1 - 1.9e-10 41.3 0.0 7e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74064.1 - 1.3e-09 38.0 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX74064.1 - 4.5e-07 29.8 0.0 7.7e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXX74064.1 - 3.7e-06 26.6 0.2 6.7e-06 25.7 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KXX74064.1 - 9.2e-06 25.7 0.1 1.6e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXX74064.1 - 0.0005 19.4 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KXX74064.1 - 0.00076 20.2 0.2 0.0029 18.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 KXX74064.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KXX74064.1 - 0.0095 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KXX74064.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KXX74064.1 - 0.033 15.2 0.0 0.11 13.5 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KXX74064.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 KXX74064.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0242 PF06785.11 KXX74064.1 - 0.087 12.9 2.0 0.14 12.3 2.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-B_dimeris PF09026.10 KXX74064.1 - 1.3 9.4 7.1 0.065 13.6 1.3 1.7 2 0 0 2 2 1 0 Centromere protein B dimerisation domain OPT PF03169.15 KXX74065.1 - 1e-148 496.8 25.3 1.2e-148 496.5 25.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peripla_BP_3 PF13377.6 KXX74065.1 - 0.093 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Epiglycanin_C PF14654.6 KXX74065.1 - 0.15 12.1 5.5 2.9 8.0 0.1 3.6 4 0 0 4 4 4 0 Mucin, catalytic, TM and cytoplasmic tail region Phage_holin_2_1 PF04971.12 KXX74065.1 - 0.47 10.5 4.9 0.6 10.2 0.1 3.3 3 0 0 3 3 3 0 Bacteriophage P21 holin S Rav1p_C PF12234.8 KXX74066.1 - 1.4e-284 945.4 0.0 1.8e-284 945.1 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal SpoIISB_antitox PF14185.6 KXX74066.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.6 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system Zds_C PF08632.10 KXX74067.1 - 1.6e-28 98.2 1.0 2.7e-28 97.5 1.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Nucleo_P87 PF07267.11 KXX74067.1 - 0.13 11.1 12.9 0.25 10.1 12.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2433 PF10360.9 KXX74068.1 - 2.5e-50 169.7 0.0 3.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KXX74068.1 - 0.00074 20.1 0.0 0.0015 19.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX74068.1 - 0.0043 17.3 0.0 0.019 15.2 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CCDC53 PF10152.9 KXX74068.1 - 0.12 12.8 2.4 0.54 10.7 2.4 2.0 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Smr PF01713.21 KXX74069.1 - 0.00036 20.8 0.6 0.0011 19.3 0.6 1.9 1 1 0 1 1 1 1 Smr domain CUE PF02845.16 KXX74069.1 - 0.0013 18.4 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain Amidase PF01425.21 KXX74070.1 - 2.2e-73 247.8 0.0 2.4e-72 244.3 0.0 1.9 1 1 0 1 1 1 1 Amidase CN_hydrolase PF00795.22 KXX74071.1 - 3.6e-25 88.8 0.0 1.2e-24 87.1 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Aha1_N PF09229.11 KXX74072.1 - 1.2e-41 142.1 1.4 2e-41 141.4 1.4 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KXX74072.1 - 2e-20 73.3 1.4 3.3e-20 72.6 0.5 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein NPC1_N PF16414.5 KXX74073.1 - 3.2e-83 279.0 6.5 4.6e-83 278.5 6.5 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KXX74073.1 - 4.5e-76 256.6 9.5 1.5e-75 254.9 9.5 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KXX74073.1 - 2.2e-50 170.5 7.7 2.2e-50 170.5 7.7 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KXX74073.1 - 7.3e-05 21.8 31.7 0.0013 17.8 9.0 2.5 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.14 KXX74073.1 - 0.00032 20.6 1.6 0.00068 19.5 1.6 1.5 1 0 0 1 1 1 1 Folate receptor family FAM176 PF14851.6 KXX74073.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.3 3 0 0 3 3 3 0 FAM176 family p450 PF00067.22 KXX74074.1 - 5.6e-36 124.3 0.0 1e-35 123.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXX74075.1 - 2.3e-54 184.9 0.0 1.8e-53 181.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.24 KXX74076.1 - 3.8e-36 125.0 0.2 4.7e-36 124.7 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KXX74076.1 - 0.042 13.5 0.1 2.2 7.8 0.0 2.7 3 0 0 3 3 3 0 Beta-lactamase enzyme family p450 PF00067.22 KXX74077.1 - 3.6e-28 98.5 0.0 4.1e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nse5 PF08691.10 KXX74078.1 - 0.0021 16.8 0.0 0.0026 16.5 0.0 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Cas_TM1802 PF09484.10 KXX74078.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) MFS_1 PF07690.16 KXX74079.1 - 9.9e-19 67.5 28.9 9.9e-19 67.5 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74079.1 - 4.4 6.0 21.2 0.052 12.4 9.7 2.4 2 1 0 2 2 2 0 Sugar (and other) transporter TRIQK PF15168.6 KXX74079.1 - 6.1 6.8 5.3 4.3 7.3 0.8 2.7 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family BRO1 PF03097.18 KXX74081.1 - 2.1e-123 412.0 0.2 2.1e-123 412.0 0.2 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXX74081.1 - 6.6e-83 278.4 1.7 6.6e-83 278.4 1.7 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV K-box PF01486.17 KXX74081.1 - 0.012 15.8 0.0 0.08 13.1 0.0 2.4 1 0 0 1 1 1 0 K-box region Lysyl_oxidase PF01186.17 KXX74081.1 - 0.081 12.6 1.0 0.14 11.8 1.0 1.3 1 0 0 1 1 1 0 Lysyl oxidase LprI PF07007.12 KXX74081.1 - 3.1 8.5 9.9 3.7 8.3 3.7 3.8 4 1 0 4 4 4 0 Lysozyme inhibitor LprI p450 PF00067.22 KXX74082.1 - 1.5e-31 109.7 0.0 2.4e-30 105.7 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DUF2768 PF10966.8 KXX74083.1 - 0.072 13.5 0.4 0.072 13.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) TMEM52 PF14979.6 KXX74083.1 - 0.091 12.7 0.1 0.091 12.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane 52 Fer4_5 PF12801.7 KXX74083.1 - 0.12 12.3 0.6 0.12 12.3 0.6 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Amidase PF01425.21 KXX74084.1 - 5.4e-30 104.7 0.6 1.8e-29 103.0 0.3 1.8 2 0 0 2 2 2 1 Amidase Ferric_reduct PF01794.19 KXX74085.1 - 1.3e-21 77.0 12.8 1.3e-21 77.0 12.8 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXX74085.1 - 5.3e-19 68.9 0.0 8.3e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXX74085.1 - 1.1e-10 41.6 0.0 2.1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXX74085.1 - 2e-06 28.4 0.0 4.9e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4018 PF13210.6 KXX74085.1 - 1.3 8.7 7.3 3 7.6 7.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Peptidase_S28 PF05577.12 KXX74086.1 - 8.2e-45 153.4 0.0 2.3e-44 151.9 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 3Beta_HSD PF01073.19 KXX74087.1 - 6.2e-25 87.7 0.0 1.1e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXX74087.1 - 8.6e-13 48.3 0.1 7.1e-12 45.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXX74087.1 - 4.6e-09 35.8 0.0 2.9e-06 26.6 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 KXX74087.1 - 4.3e-05 23.5 0.0 8.9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXX74087.1 - 0.00011 21.4 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX74087.1 - 0.00012 21.6 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KXX74087.1 - 0.0021 18.0 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Ctr PF04145.15 KXX74088.1 - 3.5e-41 141.3 0.1 4.6e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family EcsB PF05975.12 KXX74088.1 - 0.14 11.0 4.3 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Sensor PF13796.6 KXX74088.1 - 0.43 10.6 6.2 0.93 9.5 0.1 2.2 2 0 0 2 2 2 0 Putative sensor LapA_dom PF06305.11 KXX74088.1 - 1.4 8.8 3.7 5 7.0 0.3 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Fungal_trans_2 PF11951.8 KXX74089.1 - 2.7e-10 39.6 0.2 3.2e-10 39.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.12 KXX74090.1 - 4.2e-06 26.8 0.2 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX74090.1 - 0.00018 21.9 3.8 0.0004 20.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXX74090.1 - 0.00084 19.6 0.0 0.0031 17.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KXX74090.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_18 PF13238.6 KXX74090.1 - 0.016 15.8 0.2 0.44 11.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KXX74090.1 - 0.032 14.7 3.8 0.2 12.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXX74090.1 - 0.15 11.8 1.2 0.42 10.4 1.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXX74090.1 - 0.3 11.6 0.8 0.79 10.2 0.2 2.0 2 0 0 2 2 2 0 ABC transporter Carb_kinase PF01256.17 KXX74092.1 - 4.1e-55 186.9 0.1 5.6e-55 186.5 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KXX74092.1 - 0.0026 17.2 0.0 0.0057 16.1 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase ATP-synt_ab PF00006.25 KXX74093.1 - 2e-72 243.3 0.0 3.5e-72 242.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KXX74093.1 - 2.5e-47 160.3 0.5 4.2e-47 159.6 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KXX74093.1 - 4.2e-15 56.0 3.0 1.1e-14 54.7 3.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain YbjQ_1 PF01906.17 KXX74096.1 - 2.1e-28 99.0 0.3 2.5e-28 98.8 0.3 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding YobH PF13996.6 KXX74096.1 - 0.15 12.2 0.4 0.47 10.5 0.1 1.9 2 0 0 2 2 2 0 YobH-like protein GH131_N PF18271.1 KXX74097.1 - 3.1e-84 282.7 2.3 3.5e-84 282.5 2.3 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 KXX74097.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain DPPIV_N PF00930.21 KXX74098.1 - 1.7e-109 365.8 0.0 2.3e-109 365.4 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KXX74098.1 - 2.2e-55 187.4 2.1 3.8e-55 186.7 2.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXX74098.1 - 9.2e-06 25.4 0.6 0.00016 21.4 0.2 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 KXX74098.1 - 0.015 13.9 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 KXX74098.1 - 0.084 11.5 0.0 0.96 8.1 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Methyltranf_PUA PF13636.6 KXX74098.1 - 0.087 12.8 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF DLH PF01738.18 KXX74098.1 - 0.11 12.0 0.0 0.89 9.1 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family SDP_N PF12278.8 KXX74098.1 - 1.1 9.3 2.9 2.2 8.4 2.9 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal MFS_1 PF07690.16 KXX74100.1 - 2.5e-33 115.5 70.5 5.4e-31 107.8 39.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74100.1 - 2.5e-12 46.4 4.7 2.5e-12 46.4 4.7 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXX74100.1 - 5.6e-06 25.1 3.1 0.0011 17.5 0.8 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF4083 PF13314.6 KXX74100.1 - 0.057 13.4 0.0 18 5.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF1449 PF07290.11 KXX74100.1 - 0.28 10.8 3.1 0.26 10.9 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) TT_ORF1 PF02956.14 KXX74102.1 - 0.77 8.4 2.5 1.1 7.8 2.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 BRD4_CDT PF17105.5 KXX74102.1 - 0.83 9.3 10.3 2.4 7.8 10.3 1.8 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 PRA1 PF03208.19 KXX74103.1 - 4.2e-33 114.0 0.5 5.3e-33 113.6 0.5 1.1 1 0 0 1 1 1 1 PRA1 family protein Renin_r PF07850.14 KXX74103.1 - 0.04 14.5 0.0 0.04 14.5 0.0 1.7 2 0 0 2 2 2 0 Renin receptor-like protein DUF2207 PF09972.9 KXX74103.1 - 0.22 10.3 1.2 0.28 9.9 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNARE_assoc PF09335.11 KXX74104.1 - 0.21 12.1 0.3 0.52 10.8 0.0 1.7 2 0 0 2 2 2 0 SNARE associated Golgi protein Aldo_ket_red PF00248.21 KXX74105.1 - 8.6e-50 169.6 0.0 9.9e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Clathrin PF00637.20 KXX74105.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS p450 PF00067.22 KXX74106.1 - 4.8e-74 249.8 0.0 5.8e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KXX74108.1 - 3.6e-15 56.6 3.8 2.4e-12 47.4 0.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RibD_C PF01872.17 KXX74109.1 - 3.1e-09 37.0 0.0 3.5e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 KXX74109.1 - 1.8e-06 27.8 0.0 2.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase RTA1 PF04479.13 KXX74110.1 - 4.7e-65 219.1 7.5 5.8e-65 218.8 7.5 1.1 1 0 0 1 1 1 1 RTA1 like protein UNC-50 PF05216.13 KXX74110.1 - 0.06 12.9 0.4 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 UNC-50 family Tetraspanin PF00335.20 KXX74110.1 - 2.6 7.7 7.5 1.4 8.6 1.4 2.7 3 0 0 3 3 3 0 Tetraspanin family DUF3007 PF11460.8 KXX74110.1 - 3.1 8.1 6.4 0.66 10.3 1.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) Fungal_trans_2 PF11951.8 KXX74111.1 - 0.0011 17.8 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXX74113.1 - 9.7e-06 25.8 11.9 0.0032 17.8 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX74113.1 - 0.00029 21.1 3.8 0.00029 21.1 3.8 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX74113.1 - 0.0006 20.4 11.3 0.078 13.9 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Nucleo_P87 PF07267.11 KXX74113.1 - 0.38 9.5 5.5 1.1 8.0 5.2 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 zf-H2C2_5 PF13909.6 KXX74113.1 - 1.3 8.8 5.6 2.6 7.9 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Colipase PF01114.18 KXX74114.1 - 0.0059 16.2 3.6 0.01 15.5 3.6 1.3 1 0 0 1 1 1 1 Colipase, N-terminal domain MoaC PF01967.21 KXX74115.1 - 3.8e-43 146.8 0.0 6e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KXX74115.1 - 3.8e-34 117.4 0.0 7.8e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KXX74115.1 - 6e-26 91.8 0.0 1.1e-25 91.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXX74115.1 - 8e-06 26.2 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXX74115.1 - 0.14 12.3 0.1 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain dCMP_cyt_deam_1 PF00383.23 KXX74116.1 - 6.9e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXX74116.1 - 0.009 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase FolB PF02152.18 KXX74117.1 - 1.2e-35 122.4 0.0 1.3e-17 64.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase Fig1 PF12351.8 KXX74118.1 - 3.9e-23 82.3 2.0 4e-23 82.3 0.1 1.7 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KXX74118.1 - 7.6e-07 29.0 2.9 1.1e-06 28.4 2.9 1.3 1 1 0 1 1 1 1 SUR7/PalI family Virul_fac_BrkB PF03631.15 KXX74118.1 - 4.2e-05 23.3 3.0 4.2e-05 23.3 3.0 1.6 2 0 0 2 2 2 1 Virulence factor BrkB PTR2 PF00854.21 KXX74118.1 - 0.00037 19.5 0.5 0.00058 18.8 0.5 1.3 1 0 0 1 1 1 1 POT family TM140 PF14985.6 KXX74118.1 - 0.41 10.2 3.7 3.9 7.0 0.0 3.0 2 1 1 3 3 3 0 TM140 protein family FolB PF02152.18 KXX74119.1 - 4.2e-07 30.5 0.0 6.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Dihydroneopterin aldolase Epimerase PF01370.21 KXX74120.1 - 1.2e-09 38.0 0.0 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX74120.1 - 0.00021 20.4 0.0 0.0014 17.7 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXX74120.1 - 0.00096 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXX74120.1 - 0.0044 16.2 1.6 0.0048 16.1 0.4 1.7 2 1 0 2 2 2 1 Male sterility protein B12-binding PF02310.19 KXX74120.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain GDP_Man_Dehyd PF16363.5 KXX74120.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXX74120.1 - 0.054 13.0 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family PBP PF01161.20 KXX74122.1 - 3.9e-12 46.6 0.1 4.8e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Cation_efflux PF01545.21 KXX74123.1 - 4.3e-12 46.2 7.3 4.9e-12 46.0 7.3 1.1 1 0 0 1 1 1 1 Cation efflux family Gly_transf_sug PF04488.15 KXX74124.1 - 5.4e-11 43.0 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KXX74124.1 - 0.00061 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain CorA PF01544.18 KXX74125.1 - 1.8e-12 47.2 3.2 7.3e-11 41.9 3.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-C2H2 PF00096.26 KXX74126.1 - 1.6e-05 25.1 0.7 1.6e-05 25.1 0.7 2.8 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX74126.1 - 0.00021 21.9 0.5 0.00021 21.9 0.5 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXX74126.1 - 0.00046 20.1 0.7 0.00046 20.1 0.7 2.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KXX74126.1 - 0.004 17.5 1.0 0.004 17.5 1.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXX74126.1 - 0.02 15.2 9.5 0.19 12.1 1.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KXX74126.1 - 1.8 8.6 7.3 0.29 11.2 0.3 2.4 2 0 0 2 2 2 0 BED zinc finger zf-DBF PF07535.12 KXX74126.1 - 3.9 7.7 7.9 12 6.1 1.2 2.4 2 0 0 2 2 2 0 DBF zinc finger zf-H2C2_2 PF13465.6 KXX74126.1 - 5.8 7.5 12.2 0.21 12.1 0.9 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-HYPF PF07503.12 KXX74126.1 - 6.4 6.6 8.1 4.1 7.3 1.7 2.4 2 0 0 2 2 2 0 HypF finger Gram_pos_anchor PF00746.21 KXX74127.1 - 0.055 13.4 1.1 0.055 13.4 1.1 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Podoplanin PF05808.11 KXX74127.1 - 0.083 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Podoplanin Ribosomal_L23 PF00276.20 KXX74129.1 - 8.4e-11 42.1 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DJ-1_PfpI PF01965.24 KXX74130.1 - 2.5e-12 46.9 0.0 3.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXX74130.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like B_solenoid_dext PF18841.1 KXX74130.1 - 0.11 12.8 0.0 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 Beta solenoid repeat from Dextranase Hamartin PF04388.12 KXX74131.1 - 3.9e-21 75.4 0.0 3.9e-21 75.4 0.0 3.3 2 1 1 3 3 3 2 Hamartin protein LURAP PF14854.6 KXX74131.1 - 0.21 11.6 4.4 0.19 11.7 1.1 2.6 2 1 0 2 2 2 0 Leucine rich adaptor protein Spc7 PF08317.11 KXX74131.1 - 1.5 7.6 31.4 0.023 13.6 15.5 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein LCE PF14672.6 KXX74132.1 - 0.025 15.2 0.2 0.068 13.8 0.2 1.8 1 0 0 1 1 1 0 Late cornified envelope Mito_carr PF00153.27 KXX74133.1 - 6.9e-61 202.2 2.1 2.1e-21 75.6 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein MT-A70 PF05063.14 KXX74134.1 - 3.3e-28 98.7 0.0 4.5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 MT-A70 NMT1 PF09084.11 KXX74134.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like CDC73_C PF05179.14 KXX74135.1 - 4.6e-55 185.6 0.0 6.9e-55 185.0 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal RGS PF00615.19 KXX74136.1 - 6.2e-38 129.7 0.6 4.4e-37 127.0 0.0 2.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 KXX74136.1 - 1.3e-25 89.3 0.0 1.8e-21 75.9 0.0 3.4 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 KXX74136.1 - 0.028 14.5 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 Replication-relaxation ORC4_C PF14629.6 KXX74138.1 - 7.5e-69 231.4 0.0 1.2e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KXX74138.1 - 5.4e-14 52.9 0.1 1e-13 52.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.6 KXX74138.1 - 4.2e-13 48.6 2.8 7.4e-13 47.8 2.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KXX74138.1 - 6e-11 42.1 6.2 1e-10 41.3 6.2 1.4 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 KXX74138.1 - 5e-09 36.7 0.1 1.5e-08 35.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXX74138.1 - 5.8e-08 32.8 0.0 1.4e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXX74138.1 - 1.9e-06 28.2 0.0 4.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXX74138.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KXX74138.1 - 0.00028 20.2 0.1 0.00048 19.4 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF815 PF05673.13 KXX74138.1 - 0.00042 19.5 0.0 0.00069 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KXX74138.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX74138.1 - 0.0042 17.4 0.0 0.0075 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 KXX74138.1 - 0.0046 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain TniB PF05621.11 KXX74138.1 - 0.0062 16.0 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein KAP_NTPase PF07693.14 KXX74138.1 - 0.0076 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.6 KXX74138.1 - 0.0077 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain C1_1 PF00130.22 KXX74138.1 - 0.0077 16.1 0.4 0.015 15.2 0.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KXX74138.1 - 0.0086 16.0 3.0 0.0086 16.0 3.0 1.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 KXX74138.1 - 0.0093 16.2 1.3 0.02 15.1 1.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger ABC_tran PF00005.27 KXX74138.1 - 0.02 15.4 0.0 0.052 14.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter zf-PHD-like PF15446.6 KXX74138.1 - 0.043 13.5 0.8 0.075 12.6 0.3 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Sigma54_activat PF00158.26 KXX74138.1 - 0.045 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KXX74138.1 - 0.065 13.0 0.1 0.27 11.0 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KXX74138.1 - 0.073 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXX74138.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KXX74138.1 - 0.11 13.1 0.0 0.34 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KXX74138.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin IHO1 PF15771.5 KXX74138.1 - 0.41 9.3 5.7 0.59 8.8 5.7 1.2 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Zf_RING PF16744.5 KXX74138.1 - 0.55 10.4 4.3 1.2 9.2 4.3 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Prim_Zn_Ribbon PF08273.12 KXX74138.1 - 1.7 9.0 4.2 7.8 6.9 4.2 2.0 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Hamartin PF04388.12 KXX74139.1 - 2.2 6.8 14.8 2.8 6.5 14.8 1.1 1 0 0 1 1 1 0 Hamartin protein SPX PF03105.19 KXX74139.1 - 7.1 6.4 10.6 8.5 6.2 10.6 1.2 1 0 0 1 1 1 0 SPX domain FAD_binding_3 PF01494.19 KXX74141.1 - 3.5e-37 128.5 0.0 5.4e-36 124.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX74141.1 - 1.5e-05 24.8 0.0 0.06 12.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX74141.1 - 0.00095 19.4 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXX74141.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KXX74141.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXX74141.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein GIT_SHD PF08518.11 KXX74141.1 - 0.35 10.5 3.0 0.84 9.3 3.0 1.7 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Sulfotransfer_4 PF17784.1 KXX74143.1 - 2.3e-63 213.9 0.0 2.9e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXX74143.1 - 0.00041 20.8 0.4 0.14 12.5 0.1 2.7 1 1 1 2 2 2 2 Sulfotransferase family AltA1 PF16541.5 KXX74144.1 - 0.00024 21.9 0.2 0.032 15.1 0.2 2.4 2 0 0 2 2 2 2 Alternaria alternata allergen 1 Ig_GlcNase PF18368.1 KXX74145.1 - 1.4e-32 112.0 1.7 2.1e-32 111.4 0.3 2.1 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KXX74145.1 - 1.2e-11 45.3 0.7 1.3e-10 41.9 0.0 2.8 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KXX74145.1 - 1.1e-05 26.0 0.1 6.4e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KXX74145.1 - 0.0001 22.0 0.1 0.00027 20.6 0.1 1.7 1 0 0 1 1 1 1 Ig-fold domain Caleosin PF05042.13 KXX74146.1 - 1.4e-74 249.7 0.3 1.7e-74 249.4 0.3 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 KXX74146.1 - 2.1e-06 27.2 0.9 0.038 13.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KXX74146.1 - 0.00066 19.0 1.8 7.8 6.3 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KXX74146.1 - 0.00068 19.0 5.0 1.4 8.6 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KXX74146.1 - 0.016 15.6 0.0 12 6.4 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair Amidohydro_1 PF01979.20 KXX74147.1 - 6.4e-19 68.5 0.0 1.1e-18 67.7 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXX74147.1 - 2e-06 27.6 1.7 0.00067 19.2 0.1 2.9 2 1 1 3 3 3 2 Amidohydrolase family Glyco_hydro_43 PF04616.14 KXX74148.1 - 4.4e-10 39.4 0.2 2.2e-07 30.5 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KXX74148.1 - 0.00021 21.0 0.0 0.0021 17.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain ADH_zinc_N PF00107.26 KXX74149.1 - 9e-26 90.4 0.4 1.8e-25 89.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX74149.1 - 1.1e-14 55.6 0.0 3.1e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX74149.1 - 7.1e-12 45.2 0.1 3.1e-11 43.1 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KXX74149.1 - 0.00066 19.9 0.0 0.0019 18.5 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KXX74149.1 - 0.0026 17.1 4.0 0.02 14.2 0.9 2.2 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain RTBV_P12 PF06361.11 KXX74149.1 - 0.048 14.1 0.3 13 6.2 0.0 3.1 3 0 0 3 3 3 0 Rice tungro bacilliform virus P12 protein NAD_kinase PF01513.21 KXX74149.1 - 0.05 12.8 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase SIS_2 PF13580.6 KXX74149.1 - 0.058 13.4 0.1 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 SIS domain DUF4748 PF15932.5 KXX74150.1 - 7.8e-25 86.4 0.5 7.8e-25 86.4 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4748) CTD_bind PF04818.13 KXX74150.1 - 1.8e-12 47.9 0.2 3.9e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. B56 PF01603.20 KXX74151.1 - 2.8e-09 36.4 0.4 3.3e-09 36.2 0.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.20 KXX74152.1 - 1.5e-174 580.9 3.8 1.8e-174 580.6 3.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KXX74152.1 - 6e-06 26.3 1.2 0.0036 17.2 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Questin_oxidase PF14027.6 KXX74153.1 - 4.3e-98 329.0 1.0 5.1e-98 328.7 1.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like DUF3669 PF12417.8 KXX74153.1 - 0.21 11.8 1.5 7.5 6.8 0.2 2.5 1 1 1 2 2 2 0 Zinc finger protein Exo_endo_phos PF03372.23 KXX74154.1 - 2.8e-10 40.1 0.2 7.5e-10 38.7 0.1 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BCDHK_Adom3 PF10436.9 KXX74155.1 - 6e-47 159.5 1.3 1.2e-46 158.5 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXX74155.1 - 1.2e-06 29.0 0.1 1.1e-05 25.9 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXX74155.1 - 0.026 14.3 0.1 0.081 12.8 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SR-25 PF10500.9 KXX74155.1 - 0.11 12.1 4.9 0.18 11.4 4.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein USP7_ICP0_bdg PF12436.8 KXX74156.1 - 3.9e-89 298.1 0.0 8e-87 290.5 0.0 2.9 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KXX74156.1 - 2.2e-76 256.2 2.2 2.1e-72 243.2 0.2 3.6 3 0 0 3 3 3 3 Ubiquitin-specific protease C-terminal UCH PF00443.29 KXX74156.1 - 1.6e-48 165.4 2.0 3.9e-48 164.2 1.7 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX74156.1 - 5e-21 75.6 0.4 1.2e-20 74.3 0.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KXX74156.1 - 9.1e-12 45.1 0.1 3e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 MATH domain Malt_amylase_C PF16657.5 KXX74156.1 - 0.037 14.2 0.1 8.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain WD40 PF00400.32 KXX74157.1 - 3.1e-42 141.7 25.2 1.7e-08 35.0 0.1 12.5 14 0 0 14 14 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74157.1 - 4.9e-24 84.5 0.0 0.0014 18.8 0.0 9.8 5 1 5 11 11 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KXX74157.1 - 6.2e-24 84.4 0.0 9.4e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KXX74157.1 - 8.1e-09 34.9 1.0 0.48 9.3 0.0 5.1 3 3 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXX74157.1 - 1.5e-07 31.5 0.8 0.027 14.4 0.1 5.8 4 3 2 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXX74157.1 - 1.4e-05 24.6 0.0 0.095 12.0 0.0 3.6 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 KXX74157.1 - 0.00031 19.5 2.0 2 7.0 0.0 4.0 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXX74157.1 - 0.0019 17.6 0.3 10 5.4 0.0 4.1 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KXX74157.1 - 0.023 13.7 0.0 1.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 KXX74157.1 - 0.07 13.6 1.3 61 4.3 0.0 4.6 5 0 0 5 5 5 0 PQQ-like domain PD40 PF07676.12 KXX74157.1 - 0.13 12.2 0.6 25 5.0 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Utp13 PF08625.11 KXX74157.1 - 0.19 11.6 0.4 0.61 10.0 0.4 2.0 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Septin PF00735.18 KXX74158.1 - 4.2e-115 383.9 0.4 5.9e-115 383.4 0.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXX74158.1 - 2.1e-07 31.0 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXX74158.1 - 4.1e-06 26.5 3.4 7.7e-05 22.3 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXX74158.1 - 6.3e-06 26.2 1.8 3e-05 24.0 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KXX74158.1 - 0.0017 18.6 0.7 0.0053 17.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KXX74158.1 - 0.0026 17.3 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KXX74158.1 - 0.0036 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXX74158.1 - 0.0077 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KXX74158.1 - 0.0087 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 KXX74158.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Casc1_N PF15927.5 KXX74158.1 - 0.017 14.8 10.5 0.047 13.4 10.5 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ras PF00071.22 KXX74158.1 - 0.019 14.5 0.6 0.062 12.9 0.5 1.9 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.6 KXX74158.1 - 0.027 14.8 1.8 0.086 13.2 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 KXX74158.1 - 0.034 13.4 0.0 0.044 13.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 KXX74158.1 - 0.042 12.9 0.4 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KXX74158.1 - 0.052 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FOXP-CC PF16159.5 KXX74158.1 - 0.055 14.1 1.0 0.055 14.1 1.0 2.4 2 1 0 2 2 1 0 FOXP coiled-coil domain ABC_tran PF00005.27 KXX74158.1 - 0.056 14.0 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KXX74158.1 - 0.079 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Val_tRNA-synt_C PF10458.9 KXX74158.1 - 0.086 13.1 1.0 0.086 13.1 1.0 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PduV-EutP PF10662.9 KXX74158.1 - 0.14 11.9 0.4 8.3 6.2 0.1 2.6 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KXX74158.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 KXX74158.1 - 0.37 10.8 6.4 4.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 KXX74158.1 - 0.98 10.0 6.0 7.8 7.1 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e DivIC PF04977.15 KXX74158.1 - 1.8 8.4 6.7 0.63 9.8 2.1 2.5 2 0 0 2 2 2 0 Septum formation initiator AAA_11 PF13086.6 KXX74158.1 - 2.4 7.8 6.3 22 4.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myc-LZ PF02344.15 KXX74158.1 - 7.1 6.8 11.7 11 6.2 5.4 3.3 2 1 0 2 2 2 0 Myc leucine zipper domain Tim17 PF02466.19 KXX74159.1 - 5.8e-39 132.9 11.9 7.6e-39 132.5 11.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HemY_N PF07219.13 KXX74161.1 - 0.019 15.1 0.6 0.78 10.0 0.0 2.4 2 0 0 2 2 2 0 HemY protein N-terminus DUF4834 PF16118.5 KXX74161.1 - 0.073 14.0 0.1 0.073 14.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 KXX74161.1 - 0.1 13.5 0.1 4.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2749 PF10907.8 KXX74161.1 - 0.27 11.4 1.0 3.7 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) OAD_gamma PF04277.13 KXX74161.1 - 0.71 10.5 0.0 0.71 10.5 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain AAA_22 PF13401.6 KXX74163.1 - 2.4e-08 34.3 0.0 6.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXX74163.1 - 4.9e-08 32.5 0.0 0.0001 21.6 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain TPR_12 PF13424.6 KXX74163.1 - 9.5e-08 32.2 0.1 6.3e-07 29.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXX74163.1 - 6.7e-06 25.8 2.7 0.057 13.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_25 PF13481.6 KXX74163.1 - 0.043 13.4 0.1 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXX74163.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KXX74163.1 - 0.1 13.0 0.0 0.57 10.5 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KXX74163.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Raptor_N PF14538.6 KXX74164.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.4 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain cwf18 PF08315.12 KXX74164.1 - 0.2 12.3 0.7 0.28 11.9 0.7 1.4 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor NPP1 PF05630.11 KXX74167.1 - 8.5e-61 205.5 0.5 9.9e-61 205.3 0.5 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF1996 PF09362.10 KXX74169.1 - 1.4e-81 273.9 0.4 1.8e-81 273.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DNase_NucA_NucB PF14040.6 KXX74170.1 - 2.5e-07 31.1 0.0 2.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB AltA1 PF16541.5 KXX74171.1 - 0.00054 20.8 7.7 0.0049 17.7 1.5 2.8 2 2 0 2 2 2 2 Alternaria alternata allergen 1 Fasciclin PF02469.22 KXX74172.1 - 7.6e-19 68.2 0.0 1.9e-15 57.2 0.0 3.0 3 0 0 3 3 3 3 Fasciclin domain Gln-synt_C PF00120.24 KXX74174.1 - 3.7e-70 236.6 0.0 5.8e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KXX74174.1 - 5.3e-15 56.0 1.9 8.1e-15 55.4 0.6 2.2 2 1 0 2 2 2 1 Amidohydrolase MR_MLE_C PF13378.6 KXX74174.1 - 0.018 14.6 0.7 0.034 13.7 0.7 1.4 1 0 0 1 1 1 0 Enolase C-terminal domain-like Semialdhyde_dhC PF02774.18 KXX74175.1 - 0.15 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Pneumo_att_G PF05539.11 KXX74175.1 - 4.4 6.8 7.3 5.8 6.4 7.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G COPIIcoated_ERV PF07970.12 KXX74176.1 - 1.9e-34 119.4 0.0 3.1e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXX74176.1 - 1.6e-21 76.4 0.0 2.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AhpC-TSA_2 PF13911.6 KXX74177.1 - 1.1e-17 64.2 0.0 2.5e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXX74177.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family WD40 PF00400.32 KXX74178.1 - 1.6e-16 60.4 4.9 0.0045 17.8 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74178.1 - 5.9e-06 26.5 0.0 0.0077 16.5 0.0 4.4 1 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXX74178.1 - 5.7e-05 22.6 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain CTP_transf_like PF01467.26 KXX74179.1 - 8.9e-25 87.5 0.0 1e-20 74.4 0.0 3.3 3 0 0 3 3 3 3 Cytidylyltransferase-like Oxysterol_BP PF01237.18 KXX74179.1 - 2.8 6.7 4.3 3.9 6.2 4.3 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Aminotran_4 PF01063.19 KXX74181.1 - 3.4e-25 89.2 0.0 4.4e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV NERD PF08378.11 KXX74182.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Nuclease-related domain UPF1_Zn_bind PF09416.10 KXX74183.1 - 2.1e-71 238.8 4.8 6.6e-71 237.2 1.7 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KXX74183.1 - 4e-62 209.4 0.0 1.1e-61 207.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXX74183.1 - 3.1e-54 184.5 4.5 6.5e-31 108.1 0.4 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KXX74183.1 - 7.7e-34 115.8 0.0 1.5e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KXX74183.1 - 7.2e-13 48.7 0.5 1.1e-11 44.8 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX74183.1 - 1.7e-10 41.4 0.2 1.4e-09 38.5 0.2 2.5 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KXX74183.1 - 9.1e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXX74183.1 - 2.2e-05 24.4 0.1 5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 KXX74183.1 - 3.7e-05 23.6 0.4 0.35 10.6 0.0 3.2 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXX74183.1 - 0.00019 20.8 0.3 0.0058 15.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KXX74183.1 - 0.00029 20.5 0.1 0.0071 15.9 0.2 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KXX74183.1 - 0.00029 20.1 0.2 0.22 10.7 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase DEAD PF00270.29 KXX74183.1 - 0.0057 16.4 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KXX74183.1 - 0.0063 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ATPase PF06745.13 KXX74183.1 - 0.0082 15.5 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.6 KXX74183.1 - 0.012 15.8 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KXX74183.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ribosomal_S13_N PF08069.12 KXX74183.1 - 0.07 13.2 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA PF00004.29 KXX74183.1 - 0.11 13.0 0.0 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXX74183.1 - 0.15 11.5 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.14 KXX74183.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PBP1_TM PF14812.6 KXX74183.1 - 0.3 11.5 1.5 0.83 10.1 1.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3435 PF11917.8 KXX74184.1 - 4.6e-68 230.1 0.2 6.1e-68 229.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) SEEEED PF14797.6 KXX74184.1 - 0.00052 20.2 17.9 0.0011 19.2 17.9 1.4 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex CCSAP PF15748.5 KXX74184.1 - 2.2 8.4 12.5 0.081 13.1 2.7 2.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated AF-4 PF05110.13 KXX74184.1 - 9 4.2 22.3 0.015 13.4 10.8 1.9 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Astro_capsid_p PF12226.8 KXX74184.1 - 9.7 5.2 8.0 17 4.5 8.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Retrotrans_gag PF03732.17 KXX74186.1 - 6.3e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Paf67 PF10255.9 KXX74188.1 - 1.8e-154 514.7 0.1 2.1e-154 514.4 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KXX74188.1 - 0.016 15.2 0.2 0.16 12.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HBS1_N PF08938.10 KXX74188.1 - 0.026 14.8 1.0 0.062 13.6 1.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus Usp PF00582.26 KXX74189.1 - 2.3e-14 54.1 0.0 7.1e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family DUF1871 PF08958.10 KXX74189.1 - 0.19 12.1 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) RRM_1 PF00076.22 KXX74190.1 - 8.4e-10 38.3 0.0 1.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 KXX74190.1 - 0.28 11.2 10.7 0.43 10.6 10.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hamartin PF04388.12 KXX74190.1 - 4.7 5.7 7.8 5.6 5.5 7.8 1.1 1 0 0 1 1 1 0 Hamartin protein RR_TM4-6 PF06459.12 KXX74190.1 - 5.3 6.8 8.5 8 6.2 8.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KXX74190.1 - 9.9 4.8 5.7 15 4.2 5.7 1.5 1 0 0 1 1 1 0 Presenilin GTP_EFTU PF00009.27 KXX74191.1 - 2.1e-55 187.3 0.0 3.3e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXX74191.1 - 3.8e-16 58.9 0.0 9.4e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXX74191.1 - 1.8e-10 41.0 0.0 4.5e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KXX74191.1 - 3e-07 30.2 0.0 1.5e-05 24.7 0.0 3.2 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.6 KXX74191.1 - 4.3e-06 26.7 0.0 8.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXX74191.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase LXG PF04740.12 KXX74192.1 - 0.029 14.1 0.0 0.033 13.9 0.0 1.0 1 0 0 1 1 1 0 LXG domain of WXG superfamily FAD_binding_4 PF01565.23 KXX74193.1 - 6.6e-18 64.8 1.5 1.4e-17 63.8 1.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX74193.1 - 1.2e-10 41.3 0.7 2.2e-10 40.5 0.7 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1772 PF08592.11 KXX74197.1 - 5.5 7.3 8.5 0.92 9.8 2.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) SUR7 PF06687.12 KXX74198.1 - 0.0055 16.4 1.8 0.0057 16.3 1.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3341 PF11821.8 KXX74200.1 - 1.3 8.7 7.3 6.9 6.3 1.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) Sulfotransfer_4 PF17784.1 KXX74201.1 - 1.2e-67 227.9 0.2 1.4e-67 227.7 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXX74201.1 - 0.00073 20.0 1.1 0.75 10.1 0.2 2.2 1 1 1 2 2 2 2 Sulfotransferase family adh_short PF00106.25 KXX74202.1 - 8.7e-20 71.0 0.0 2.8e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX74202.1 - 7.3e-13 48.6 0.0 1.1e-11 44.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXX74202.1 - 0.00018 21.0 0.1 0.00053 19.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXX74202.1 - 0.014 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 KR domain TIR-like PF10137.9 KXX74202.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Antimicrobial23 PF16048.5 KXX74202.1 - 0.4 10.4 3.5 0.76 9.5 3.5 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide GMC_oxred_N PF00732.19 KXX74203.1 - 3.3e-45 154.7 0.0 4.7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX74203.1 - 8.5e-34 117.1 0.0 1.4e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase HET PF06985.11 KXX74204.1 - 4.6e-30 104.9 0.0 1.6e-29 103.2 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HD_3 PF13023.6 KXX74206.1 - 4.8e-50 169.7 0.1 6.2e-50 169.3 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KXX74206.1 - 2.1e-10 40.7 0.0 2.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KXX74206.1 - 0.027 14.7 0.0 0.077 13.2 0.0 1.8 1 1 0 1 1 1 0 HD domain HET PF06985.11 KXX74207.1 - 9.9e-12 45.4 1.3 8.2e-11 42.4 1.3 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kindlin_2_N PF18124.1 KXX74207.1 - 0.0095 16.1 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain Tyosinase_C PF18132.1 KXX74208.1 - 0.063 13.9 0.0 0.91 10.2 0.0 2.1 1 1 1 2 2 2 0 Tyosinase C-terminal domain FAA_hydrolase PF01557.18 KXX74209.1 - 4.4e-67 225.9 0.0 5.2e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 KXX74209.1 - 0.0024 18.7 0.1 0.0071 17.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) Collar PF07484.12 KXX74209.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Collar Domain DUF3433 PF11915.8 KXX74211.1 - 5.9e-37 126.0 17.3 4.4e-20 71.9 7.1 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Alpha-L-AF_C PF06964.12 KXX74213.1 - 8.1e-21 74.9 0.0 1.4e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyoxalase PF00903.25 KXX74214.1 - 2.6e-08 34.1 7.9 1.4e-07 31.8 2.7 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXX74214.1 - 0.0008 19.7 0.1 0.051 13.9 0.1 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 KXX74215.1 - 5.1e-78 262.8 0.0 7.1e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 KXX74215.1 - 6.4e-72 242.8 0.0 9e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 KXX74215.1 - 0.0036 16.6 0.1 0.0067 15.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX74215.1 - 0.025 13.7 0.5 0.043 12.9 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KXX74215.1 - 0.033 14.4 1.3 0.076 13.3 1.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX74215.1 - 0.037 13.1 0.3 0.062 12.3 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KXX74215.1 - 0.063 12.5 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.6 KXX74215.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain GIDA PF01134.22 KXX74215.1 - 0.65 9.0 1.7 0.97 8.4 1.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PilM PF07419.12 KXX74217.1 - 0.026 14.7 0.0 0.11 12.6 0.0 2.0 2 1 1 3 3 3 0 PilM PNP_UDP_1 PF01048.20 KXX74218.1 - 1.8e-05 24.1 0.1 0.00011 21.6 0.1 2.0 1 1 1 2 2 2 1 Phosphorylase superfamily Peripla_BP_3 PF13377.6 KXX74218.1 - 0.028 14.8 0.1 0.058 13.7 0.1 1.6 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Ank_2 PF12796.7 KXX74220.1 - 1e-45 154.2 2.9 3.3e-17 62.8 0.1 4.5 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXX74220.1 - 3.4e-30 103.1 0.3 2e-05 24.8 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 KXX74220.1 - 3.9e-30 100.5 0.2 0.00033 20.9 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 KXX74220.1 - 2.7e-29 101.1 0.3 9.9e-07 29.2 0.0 5.6 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX74220.1 - 1.6e-26 92.0 0.8 5.7e-05 23.3 0.0 6.5 2 1 5 7 7 7 7 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.6 KXX74220.1 - 0.013 16.2 0.2 0.013 16.2 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX74220.1 - 0.033 14.6 0.2 0.033 14.6 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF629 PF04780.12 KXX74220.1 - 0.26 9.8 1.4 0.5 8.8 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Ank_2 PF12796.7 KXX74221.1 - 3.6e-19 69.1 5.0 1.3e-09 38.5 0.6 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX74221.1 - 1.2e-10 41.4 0.1 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX74221.1 - 1.5e-08 34.7 1.8 0.068 13.6 0.2 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXX74221.1 - 8.9e-08 32.5 0.1 0.0099 16.4 0.0 3.6 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX74221.1 - 1.8e-07 30.9 0.1 0.11 13.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat vWA-TerF-like PF10138.9 KXX74221.1 - 0.0019 18.4 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus Lebercilin PF15619.6 KXX74223.1 - 0.014 15.0 13.0 0.014 15.0 13.0 3.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.12 KXX74223.1 - 0.082 11.1 42.3 0.13 10.4 42.3 1.2 1 0 0 1 1 1 0 HOOK protein DUF3584 PF12128.8 KXX74223.1 - 0.12 9.9 42.4 0.17 9.4 42.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4250 PF14056.6 KXX74223.1 - 1.9 8.5 18.2 1.3 9.1 0.4 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4250) DUF3618 PF12277.8 KXX74223.1 - 5.7 7.3 13.4 2 8.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) SurA_N PF09312.11 KXX74223.1 - 6.2 6.9 12.9 0.57 10.3 0.7 3.2 3 0 0 3 3 3 0 SurA N-terminal domain NACHT PF05729.12 KXX74227.1 - 3.7e-18 66.0 0.1 6.8e-18 65.1 0.1 1.5 1 1 0 1 1 1 1 NACHT domain SesA PF17107.5 KXX74227.1 - 2.9e-10 40.4 0.0 2.7e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_19 PF13245.6 KXX74227.1 - 0.0092 16.3 0.1 0.014 15.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX74227.1 - 0.0095 16.3 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX74227.1 - 0.028 14.7 0.1 0.073 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXX74227.1 - 0.031 14.0 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KXX74227.1 - 0.034 13.0 0.0 0.071 12.0 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase DUF2075 PF09848.9 KXX74227.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rad51 PF08423.11 KXX74228.1 - 7.4e-38 130.3 0.0 1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KXX74228.1 - 5.1e-10 39.3 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KXX74228.1 - 4.3e-06 26.4 0.1 0.00097 18.7 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 KXX74228.1 - 6.2e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 KXX74228.1 - 0.04 13.7 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXX74228.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Caskin1-CID PF16600.5 KXX74228.1 - 4.1 8.1 9.4 12 6.6 0.9 3.2 3 0 0 3 3 3 0 Caskin1 CASK-interaction domain RNA_pol_Rpb2_6 PF00562.28 KXX74229.1 - 1.9e-99 333.4 0.0 3e-99 332.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXX74229.1 - 1.5e-50 171.6 0.0 2.3e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KXX74229.1 - 3.7e-33 113.8 1.5 8.7e-33 112.6 1.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KXX74229.1 - 4.1e-28 98.3 0.0 1.6e-27 96.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KXX74229.1 - 7.6e-22 77.4 0.1 1.9e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KXX74229.1 - 1.8e-20 72.9 0.0 3.4e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KXX74229.1 - 1.5e-12 47.8 0.4 4.4e-12 46.4 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.19 KXX74230.1 - 2e-61 200.4 11.1 5.6e-08 32.0 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KXX74230.1 - 0.0057 17.0 1.1 7.6 6.9 0.0 3.9 1 1 2 3 3 3 2 CPL (NUC119) domain Prefoldin_2 PF01920.20 KXX74230.1 - 0.3 11.1 4.6 0.32 11.0 3.3 1.7 2 0 0 2 2 2 0 Prefoldin subunit BAR PF03114.18 KXX74230.1 - 7.8 6.1 9.3 4.5 6.8 5.9 2.0 2 0 0 2 2 2 0 BAR domain Ribosomal_L15e PF00827.17 KXX74231.1 - 7.7e-90 299.8 8.9 9.4e-90 299.5 8.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Carn_acyltransf PF00755.20 KXX74233.1 - 4e-212 706.0 0.0 2.2e-184 614.4 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase MacB_PCD PF12704.7 KXX74234.1 - 3 8.1 5.7 1.5 9.2 0.5 2.2 1 1 1 2 2 2 0 MacB-like periplasmic core domain DUF2205 PF10224.9 KXX74236.1 - 4.7e-36 122.6 1.2 5.4e-36 122.4 1.2 1.0 1 0 0 1 1 1 1 Short coiled-coil protein DUF3450 PF11932.8 KXX74236.1 - 0.016 14.6 0.2 0.017 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AA_permease_2 PF13520.6 KXX74237.1 - 1e-58 199.2 33.0 1.3e-58 198.9 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX74237.1 - 3.4e-21 75.4 35.2 2.4e-20 72.6 35.1 1.9 1 1 0 1 1 1 1 Amino acid permease ECH_1 PF00378.20 KXX74238.1 - 4.9e-18 65.3 2.3 1.5e-10 40.8 0.6 4.1 3 1 1 4 4 4 4 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX74238.1 - 0.00033 20.2 0.3 0.11 12.0 0.1 2.9 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase RCDG1 PF15725.5 KXX74238.1 - 3.2 8.2 9.9 1.8 9.1 7.5 1.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Sugar_tr PF00083.24 KXX74239.1 - 2.7e-79 267.1 22.4 3.2e-79 266.9 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX74239.1 - 1.1e-28 100.2 22.3 1.1e-28 100.2 22.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXX74239.1 - 0.0024 16.5 8.4 0.0024 16.5 8.4 2.6 3 1 0 3 3 3 1 MFS/sugar transport protein HET PF06985.11 KXX74240.1 - 9.9e-26 90.8 0.0 2e-25 89.9 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KXX74241.1 - 2.7e-37 127.2 0.0 2.7e-11 43.9 0.0 4.6 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXX74241.1 - 9.9e-31 104.8 3.0 0.00044 20.6 0.0 8.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 KXX74241.1 - 1.6e-29 101.9 0.0 8.4e-06 26.2 0.0 5.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX74241.1 - 1e-25 86.9 1.4 0.0027 18.0 0.0 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KXX74241.1 - 2.6e-25 88.2 2.6 2.2e-05 24.6 0.0 6.4 3 1 2 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.12 KXX74242.1 - 0.0078 16.1 0.1 0.021 14.8 0.1 1.7 1 1 1 2 2 2 1 NACHT domain PNP_UDP_1 PF01048.20 KXX74243.1 - 0.00056 19.2 2.9 0.0036 16.6 2.9 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily ssDNA_TraI_N PF18272.1 KXX74243.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Ank_2 PF12796.7 KXX74246.1 - 2.4e-13 50.5 0.0 3.6e-12 46.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX74246.1 - 2.7e-13 50.1 0.0 1.2e-07 32.1 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX74246.1 - 1.4e-10 40.4 0.0 0.00022 21.4 0.0 5.2 6 0 0 6 6 4 2 Ankyrin repeat Ank PF00023.30 KXX74246.1 - 5.2e-08 33.0 0.0 0.00022 21.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXX74246.1 - 3e-07 30.6 0.0 1.2e-06 28.6 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NACHT PF05729.12 KXX74246.1 - 9.9e-07 28.8 0.1 4e-06 26.8 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX74246.1 - 5e-05 23.8 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KXX74246.1 - 0.0019 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX74246.1 - 0.0039 17.5 0.0 0.0096 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXX74246.1 - 0.059 13.1 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KXX74246.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KXX74246.1 - 0.1 13.1 0.0 0.3 11.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 KXX74246.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HflK_N PF12221.8 KXX74246.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal AAA_18 PF13238.6 KXX74246.1 - 0.15 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX74246.1 - 0.16 11.7 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Glyco_hydro_3 PF00933.21 KXX74247.1 - 8e-39 133.9 0.0 1.3e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXX74247.1 - 3.7e-38 131.5 0.0 8.9e-38 130.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXX74247.1 - 2.7e-23 81.9 0.1 4.5e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CN_hydrolase PF00795.22 KXX74248.1 - 6.5e-60 202.7 0.0 7.4e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_10 PF00331.20 KXX74249.1 - 1.5e-88 297.0 0.0 1.7e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.24 KXX74249.1 - 0.026 13.9 0.1 0.3 10.5 0.0 2.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel DpaA_N PF16924.5 KXX74249.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain RuvC_1 PF18516.1 KXX74249.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 RuvC nuclease domain OrsD PF12013.8 KXX74250.1 - 1.1e-09 38.8 0.1 2.1e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Uds1 PF15456.6 KXX74251.1 - 4.7e-31 107.7 9.6 4.7e-31 107.7 9.6 1.9 2 0 0 2 2 2 1 Up-regulated During Septation Stathmin PF00836.19 KXX74251.1 - 0.022 14.7 0.6 0.022 14.7 0.6 2.6 3 0 0 3 3 3 0 Stathmin family G-alpha PF00503.20 KXX74252.1 - 1.6e-110 369.6 0.1 1.9e-110 369.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXX74252.1 - 1.2e-13 50.9 0.6 1.8e-08 34.1 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXX74252.1 - 5.7e-05 22.6 0.4 0.0081 15.5 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KXX74252.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 KXX74252.1 - 0.026 14.7 0.3 6 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KXX74252.1 - 0.032 13.9 0.1 0.04 13.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXX74252.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KXX74252.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Spermine_synth PF01564.17 KXX74253.1 - 1.6e-73 246.1 0.0 3e-73 245.3 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KXX74253.1 - 9e-27 92.7 0.1 1.5e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KXX74253.1 - 9.2e-05 23.1 0.0 0.00016 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 KXX74253.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 KXX74253.1 - 0.0017 19.0 0.3 0.0081 16.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXX74253.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KXX74253.1 - 0.061 12.6 0.2 0.26 10.5 0.1 1.8 1 1 1 2 2 2 0 O-methyltransferase domain Methyltransf_30 PF05430.11 KXX74253.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 KXX74253.1 - 0.1 13.6 0.0 0.23 12.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF4848 PF16140.5 KXX74253.1 - 0.13 11.8 0.0 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4848) Zn_clus PF00172.18 KXX74255.1 - 3.9e-07 30.1 7.4 5.8e-07 29.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 KXX74255.1 - 0.5 10.8 3.4 0.88 10.1 3.4 1.4 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family DUF202 PF02656.15 KXX74256.1 - 3.6e-05 24.1 2.7 6.7e-05 23.3 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ycf4 PF02392.16 KXX74256.1 - 3.6 7.1 5.4 0.41 10.2 0.6 1.8 2 1 0 2 2 2 0 Ycf4 DAD PF02109.16 KXX74257.1 - 6.1e-45 152.0 0.5 7.6e-45 151.7 0.5 1.1 1 0 0 1 1 1 1 DAD family MCPVI PF02993.14 KXX74257.1 - 4.6 7.0 8.6 6.7 6.5 8.6 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DEC-1_N PF04625.13 KXX74257.1 - 8.3 5.3 9.2 9.6 5.1 9.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GRASP55_65 PF04495.14 KXX74258.1 - 4.7e-48 163.0 0.0 1e-46 158.6 0.0 2.1 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KXX74258.1 - 0.0025 17.6 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain zf-HIT PF04438.16 KXX74260.1 - 5.1e-08 32.6 9.9 7.3e-08 32.1 9.9 1.2 1 0 0 1 1 1 1 HIT zinc finger Barwin PF00967.17 KXX74260.1 - 0.11 12.4 3.8 0.22 11.4 3.8 1.4 1 0 0 1 1 1 0 Barwin family Spem1 PF15670.5 KXX74260.1 - 4.8 6.7 8.2 15 5.1 3.0 2.8 2 1 0 3 3 3 0 Spermatid maturation protein 1 CENP-Q PF13094.6 KXX74261.1 - 0.23 11.7 1.4 0.35 11.0 1.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Thioredoxin PF00085.20 KXX74262.1 - 3.7e-62 206.7 5.5 2.3e-31 107.8 0.3 3.8 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KXX74262.1 - 2e-47 161.5 2.3 4e-35 121.4 0.3 3.5 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXX74262.1 - 3.3e-08 33.7 0.1 0.034 14.5 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KXX74262.1 - 5.7e-08 32.8 0.1 0.0037 17.4 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 KXX74262.1 - 6.6e-08 32.4 3.5 0.0059 16.3 0.0 3.6 3 0 0 3 3 3 3 Redoxin AhpC-TSA PF00578.21 KXX74262.1 - 9.8e-08 32.0 2.0 0.01 15.8 0.1 3.4 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KXX74262.1 - 1.2e-07 32.1 0.6 0.0062 17.0 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXX74262.1 - 2.6e-07 30.3 1.1 0.011 15.1 0.1 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KXX74262.1 - 2.8e-06 26.6 1.6 5.8e-06 25.6 1.6 1.5 1 0 0 1 1 1 1 Calsequestrin ERp29_N PF07912.13 KXX74262.1 - 6.5e-05 23.1 4.3 0.32 11.2 0.2 4.5 3 2 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 KXX74262.1 - 0.22 11.6 0.7 0.88 9.7 0.0 2.3 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_4 PF13462.6 KXX74262.1 - 0.35 11.0 7.3 2.4 8.3 0.5 3.7 3 2 0 3 3 3 0 Thioredoxin Mon1 PF03164.14 KXX74263.1 - 4.2e-152 506.9 0.0 4.9e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 KXX74264.1 - 3.3e-116 387.7 0.0 9.3e-116 386.2 0.0 1.8 1 0 0 1 1 1 1 Dopey, N-terminal APC1_C PF18122.1 KXX74264.1 - 0.04 13.9 1.4 9.8 6.1 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain Methyltransf_15 PF09445.10 KXX74265.1 - 3.3e-45 153.6 0.0 5.6e-45 152.9 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KXX74265.1 - 2.9e-05 23.9 0.0 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KXX74265.1 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 KXX74265.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_3 PF01596.17 KXX74265.1 - 0.021 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.14 KXX74265.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.18 KXX74265.1 - 0.068 12.9 0.1 0.19 11.4 0.1 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_5 PF01795.19 KXX74265.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Methyltransf_18 PF12847.7 KXX74265.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DNA_methylase PF00145.17 KXX74265.1 - 0.22 10.8 0.1 0.33 10.2 0.1 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Aminotran_5 PF00266.19 KXX74266.1 - 2.2e-26 92.7 0.0 2.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DASH_Dad2 PF08654.10 KXX74267.1 - 1.3e-28 99.3 4.0 6.1e-28 97.2 4.0 1.9 1 1 0 1 1 1 1 DASH complex subunit Dad2 APG6_N PF17675.1 KXX74267.1 - 0.018 15.6 0.3 0.021 15.3 0.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region p450 PF00067.22 KXX74268.1 - 7.3e-68 229.4 0.0 8.4e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CRM1_C PF08767.11 KXX74269.1 - 3.2e-131 437.3 2.3 3.2e-131 437.3 2.3 3.0 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KXX74269.1 - 1.8e-41 141.7 6.4 1.8e-41 141.7 6.4 3.3 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KXX74269.1 - 4.1e-34 116.0 4.7 1.4e-33 114.4 4.7 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KXX74269.1 - 9.8e-28 96.0 1.2 9.8e-28 96.0 1.2 3.3 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KXX74269.1 - 1.6e-19 69.1 1.4 5.1e-19 67.5 1.4 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KXX74269.1 - 1.5e-11 44.1 0.0 6.4e-11 42.0 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KXX74269.1 - 0.02 15.5 0.7 1.2 9.8 0.0 4.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region BID PF06393.11 KXX74269.1 - 0.062 12.8 0.3 0.19 11.2 0.3 1.8 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF3385 PF11865.8 KXX74269.1 - 0.064 13.2 2.9 0.3 11.0 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Prolamin_like PF05617.11 KXX74269.1 - 0.14 12.3 1.5 3.1 8.0 0.0 3.6 3 0 0 3 3 3 0 Prolamin-like IBR PF01485.21 KXX74270.1 - 3.7e-12 46.3 28.5 9e-09 35.4 7.3 4.6 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain COesterase PF00135.28 KXX74272.1 - 5e-75 253.3 0.0 8e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX74272.1 - 3.3e-07 30.4 0.7 1.4e-06 28.3 0.2 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold TMEM135_C_rich PF15982.5 KXX74273.1 - 0.00043 20.9 0.5 0.0028 18.2 0.1 2.5 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 DUF1616 PF07760.11 KXX74273.1 - 0.061 12.7 0.2 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF2798 PF11391.8 KXX74273.1 - 5 7.2 10.0 2.4 8.3 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2798) IMS PF00817.20 KXX74274.1 - 1.1e-32 113.1 0.0 1.7e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXX74274.1 - 5.6e-13 49.6 0.0 1.2e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXX74274.1 - 0.0098 16.2 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif UPF0547 PF10571.9 KXX74274.1 - 0.063 13.4 0.3 3.2 7.9 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 HLH PF00010.26 KXX74275.1 - 2.5e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nucleo_P87 PF07267.11 KXX74275.1 - 1.1 8.0 5.2 1.5 7.5 5.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC27 PF09507.10 KXX74275.1 - 1.3 8.4 12.2 2.1 7.6 12.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Shugoshin_N PF07558.11 KXX74276.1 - 1.3e-17 63.3 4.5 2.5e-17 62.5 4.5 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KXX74276.1 - 2.4e-11 43.2 5.6 2.4e-11 43.2 5.6 2.3 2 0 0 2 2 2 1 Shugoshin C terminus CCDC85 PF10226.9 KXX74276.1 - 0.017 14.8 0.5 0.062 13.0 0.5 1.9 1 0 0 1 1 1 0 CCDC85 family TMCO5 PF14992.6 KXX74276.1 - 0.2 11.2 1.7 0.36 10.4 1.7 1.3 1 0 0 1 1 1 0 TMCO5 family GIT_CC PF16559.5 KXX74276.1 - 0.26 11.2 1.6 0.61 10.0 1.6 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1465 PF07323.12 KXX74276.1 - 1.5 8.7 6.4 0.15 11.9 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Cep57_CLD PF14073.6 KXX74276.1 - 5.5 7.0 11.7 0.084 12.9 3.7 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Bac_rhamnosid_C PF17390.2 KXX74277.1 - 0.017 14.9 0.4 0.048 13.5 0.1 1.9 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain Rad54_N PF08658.10 KXX74277.1 - 0.024 14.8 0.1 0.031 14.4 0.1 1.1 1 0 0 1 1 1 0 Rad54 N terminal Metallophos_2 PF12850.7 KXX74278.1 - 6.1e-13 49.3 0.0 7.6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KXX74278.1 - 0.01 16.3 0.0 0.058 13.9 0.0 1.9 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase RPEL PF02755.15 KXX74279.1 - 4.9e-20 70.6 4.5 2.8e-10 39.5 0.2 2.5 3 0 0 3 3 3 2 RPEL repeat GMC_oxred_N PF00732.19 KXX74280.1 - 2.2e-50 171.7 0.0 3.5e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX74280.1 - 5.3e-30 104.8 0.1 8.6e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXX74280.1 - 0.093 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX74280.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_18 PF00704.28 KXX74281.1 - 2.9e-64 217.8 0.0 3.3e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PALP PF00291.25 KXX74283.1 - 3.4e-80 269.6 0.5 4.2e-80 269.3 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXX74283.1 - 7.1e-38 128.3 0.0 1.2e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase FKBP_C PF00254.28 KXX74284.1 - 2.1e-31 108.1 0.0 3e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Tannase PF07519.11 KXX74285.1 - 2.6e-99 333.3 0.3 3.3e-99 332.9 0.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXX74285.1 - 0.046 13.0 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 IMS PF00817.20 KXX74286.1 - 1.3e-42 145.4 0.0 2.8e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXX74286.1 - 4.4e-13 49.9 0.2 1.3e-12 48.4 0.2 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXX74286.1 - 8.5e-06 25.8 0.0 2.7e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Syntaxin PF00804.25 KXX74287.1 - 1.7e-19 70.3 17.3 4.1e-19 69.1 17.3 1.6 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 KXX74287.1 - 1.3e-11 44.3 2.2 2.9e-11 43.2 2.2 1.6 1 0 0 1 1 1 1 SNARE domain SARAF PF06682.12 KXX74287.1 - 0.00032 20.4 0.4 0.00077 19.2 0.0 1.7 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis GRA6 PF05084.13 KXX74287.1 - 0.016 15.2 4.6 0.016 15.2 4.6 2.3 3 0 0 3 3 3 0 Granule antigen protein (GRA6) Syntaxin_2 PF14523.6 KXX74287.1 - 0.065 13.6 7.4 0.66 10.4 6.9 2.6 1 1 0 1 1 1 0 Syntaxin-like protein DASH_Dad3 PF08656.10 KXX74287.1 - 0.24 11.5 2.8 4 7.6 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad3 RRT14 PF17075.5 KXX74287.1 - 0.35 11.0 8.1 0.11 12.7 2.1 2.4 1 1 0 2 2 2 0 Regular of rDNA transcription protein 14 ETRAMP PF09716.10 KXX74287.1 - 0.53 10.4 0.0 0.53 10.4 0.0 2.2 2 0 0 2 2 1 0 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 KXX74287.1 - 1.9 8.9 12.6 0.064 13.6 0.9 3.0 2 1 1 3 3 3 0 Orf78 (ac78) Chordopox_A13L PF05961.11 KXX74287.1 - 4.2 7.7 5.3 12 6.2 5.3 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Chorion_3 PF05387.11 KXX74287.1 - 5.4 6.6 13.0 0.92 9.1 4.5 2.3 2 0 0 2 2 2 0 Chorion family 3 Allexi_40kDa PF05549.11 KXX74287.1 - 7.5 6.0 7.2 1.2 8.6 2.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein Memo PF01875.17 KXX74288.1 - 2.4e-74 249.9 0.0 2.9e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Rhodanese PF00581.20 KXX74289.1 - 3.1e-19 69.5 0.0 5.7e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain HAD_2 PF13419.6 KXX74289.1 - 0.21 11.6 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TLD PF07534.16 KXX74290.1 - 2.7e-28 99.0 0.0 8.5e-28 97.3 0.0 1.8 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 KXX74290.1 - 4.6e-16 59.6 2.1 5.1e-16 59.5 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function HIG_1_N PF04588.13 KXX74291.1 - 3.9e-21 75.0 0.5 7.2e-21 74.2 0.5 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3824 PF12868.7 KXX74291.1 - 0.59 10.8 16.7 1.4 9.6 3.2 2.4 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF4407 PF14362.6 KXX74291.1 - 0.89 8.8 9.7 1.1 8.5 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KXX74291.1 - 1.4 6.8 5.1 1.6 6.6 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 KXX74291.1 - 9.8 4.8 7.8 12 4.5 7.8 1.2 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 KXX74293.1 - 1.4e-11 44.0 21.9 1.6e-11 43.7 21.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74293.1 - 1.7e-09 37.1 10.1 2.1e-09 36.8 10.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1749 PF08538.10 KXX74294.1 - 2.9e-83 279.4 0.0 3.2e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KXX74294.1 - 2.8e-07 31.4 0.0 3.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX74294.1 - 0.0011 18.3 0.0 0.035 13.4 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX74294.1 - 0.0075 15.9 0.0 0.04 13.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX74294.1 - 0.044 13.3 0.0 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family SnoaL_2 PF12680.7 KXX74299.1 - 6.7e-06 26.7 0.2 9e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXX74299.1 - 0.0027 17.5 0.2 0.013 15.3 0.1 1.8 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase Ig_C19orf38 PF17737.1 KXX74299.1 - 0.049 14.0 0.1 0.15 12.4 0.1 1.7 1 1 1 2 2 2 0 Ig domain in C19orf38 (HIDE1) DUF1917 PF08939.10 KXX74301.1 - 0.00011 22.2 0.0 0.00013 22.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Ank_2 PF12796.7 KXX74302.1 - 1.8e-39 134.2 6.6 1.8e-11 44.4 0.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX74302.1 - 5.7e-31 106.5 1.1 5e-08 33.3 0.0 7.2 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX74302.1 - 6.4e-29 99.6 5.2 1.1e-09 38.3 0.0 6.0 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX74302.1 - 8.5e-22 74.9 1.4 0.0015 18.9 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 KXX74302.1 - 1.3e-21 76.0 3.3 0.00067 20.0 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat SesA PF17107.5 KXX74302.1 - 9.1e-05 22.6 0.6 9.1e-05 22.6 0.6 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Raptor_N PF14538.6 KXX74303.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.4 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain cwf18 PF08315.12 KXX74303.1 - 0.2 12.3 0.7 0.28 11.9 0.7 1.4 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor TPR_12 PF13424.6 KXX74304.1 - 9.7e-08 32.2 0.1 6.2e-07 29.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXX74304.1 - 6.9e-06 25.8 2.7 0.056 13.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KXX74304.1 - 3.9e-05 23.0 0.0 0.0001 21.6 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain DUF1996 PF09362.10 KXX74306.1 - 1.5e-81 273.9 0.7 1.8e-81 273.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fungal_trans PF04082.18 KXX74307.1 - 0.00042 19.4 0.1 0.00061 18.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX74307.1 - 0.0039 17.3 5.0 0.0068 16.5 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leu_Phe_trans PF03588.14 KXX74307.1 - 0.2 11.2 0.0 0.5 9.9 0.0 1.6 2 0 0 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase Opy2 PF09463.10 KXX74307.1 - 0.72 10.2 4.4 1.8 9.0 4.4 1.6 1 0 0 1 1 1 0 Opy2 protein Pectate_lyase_3 PF12708.7 KXX74310.1 - 3.7e-29 102.1 1.1 4.8e-20 72.3 0.2 3.0 2 1 0 2 2 2 2 Pectate lyase superfamily protein DUF3328 PF11807.8 KXX74311.1 - 5e-29 101.7 2.1 6e-29 101.4 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Mid2 PF04478.12 KXX74312.1 - 0.011 15.5 0.0 0.045 13.6 0.0 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor adh_short PF00106.25 KXX74313.1 - 5e-18 65.3 1.2 2.6e-16 59.7 0.3 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX74313.1 - 1.3e-12 47.8 1.6 7.8e-11 42.0 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX74313.1 - 8e-06 25.9 0.2 1.2e-05 25.3 0.2 1.2 1 0 0 1 1 1 1 KR domain DSBA PF01323.20 KXX74314.1 - 4.9e-29 101.5 0.0 9.4e-27 94.0 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KXX74314.1 - 0.004 17.2 0.2 0.43 10.7 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin domain TPR_1 PF00515.28 KXX74314.1 - 0.16 11.8 0.2 0.3 11.0 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn_clus PF00172.18 KXX74315.1 - 5.7 7.2 19.5 0.095 12.8 12.1 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 KXX74317.1 - 1.4e-85 287.6 0.0 2.1e-85 287.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXX74317.1 - 3e-06 26.0 0.0 4.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXX74317.1 - 9.1e-06 24.9 0.5 2.1e-05 23.7 0.0 1.8 3 0 0 3 3 3 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXX74317.1 - 0.0046 16.3 0.2 0.011 15.1 0.2 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family EP400_N PF15790.5 KXX74317.1 - 0.05 12.4 0.3 0.2 10.5 0.2 1.9 2 0 0 2 2 2 0 E1A-binding protein p400, N-terminal Ank_4 PF13637.6 KXX74318.1 - 3e-12 46.8 0.0 1.2e-05 25.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX74318.1 - 1.9e-10 40.7 0.2 0.021 15.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KXX74318.1 - 9.1e-10 39.0 0.0 2.4e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX74318.1 - 3.8e-09 36.6 1.6 8.6e-05 22.8 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX74318.1 - 4.8e-07 29.6 0.1 1 10.2 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat APH PF01636.23 KXX74319.1 - 8.6e-13 48.8 0.0 1.3e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXX74319.1 - 0.00077 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Lyase_1 PF00206.20 KXX74320.1 - 1.8e-21 76.8 0.2 2.8e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KXX74320.1 - 4.2e-17 62.5 0.1 5.9e-16 58.8 0.0 2.6 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HK PF02110.15 KXX74321.1 - 5.4e-75 252.0 0.2 8.3e-75 251.4 0.2 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KXX74321.1 - 2.3e-56 190.0 0.3 3.5e-56 189.4 0.3 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KXX74321.1 - 0.00034 20.2 0.1 0.00053 19.5 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KXX74321.1 - 0.005 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Glyco_hydro_3_C PF01915.22 KXX74321.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Isochorismatase PF00857.20 KXX74322.1 - 6.8e-27 94.8 0.1 8.9e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.6 KXX74323.1 - 3.2e-19 70.0 0.0 4.6e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX74323.1 - 1.3e-14 54.7 0.0 1.6e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_59 PF02057.15 KXX74324.1 - 2.4e-13 50.0 3.7 4.5e-13 49.1 3.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KXX74324.1 - 5.1e-13 49.4 0.1 5.1e-13 49.4 0.1 1.9 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 KXX74324.1 - 3.8e-12 46.3 3.3 1.3e-11 44.5 3.3 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 KXX74324.1 - 4.6e-10 39.0 0.3 6.9e-10 38.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain SNF2_N PF00176.23 KXX74325.1 - 4e-43 147.5 0.0 7e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX74325.1 - 8.1e-20 71.2 0.2 2e-19 70.0 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX74325.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXX74325.1 - 0.0028 16.9 0.0 0.0066 15.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TFIIS_M PF07500.14 KXX74325.1 - 0.0057 17.1 0.1 0.032 14.7 0.1 2.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain GSH_synth_ATP PF03917.17 KXX74326.1 - 2.3e-57 194.5 0.0 2.9e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain tRNA-synt_1c PF00749.21 KXX74329.1 - 1.3e-97 326.5 0.0 1.7e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXX74329.1 - 1.8e-32 112.6 0.0 4.9e-32 111.2 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Macro PF01661.21 KXX74330.1 - 1.2e-36 125.4 0.0 1.7e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Macro domain CsbD PF05532.12 KXX74331.1 - 1.3e-08 34.6 3.2 0.00017 21.4 0.1 2.2 2 0 0 2 2 2 2 CsbD-like ABC_tran PF00005.27 KXX74332.1 - 5.9e-47 159.6 0.1 5.6e-24 85.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KXX74332.1 - 2.3e-31 107.7 1.4 4.7e-31 106.7 0.1 2.3 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 KXX74332.1 - 5.1e-18 65.9 0.0 0.002 18.0 0.0 5.0 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX74332.1 - 8.1e-16 58.1 0.1 2.2e-05 24.0 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXX74332.1 - 8.7e-09 35.0 0.2 0.0043 16.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXX74332.1 - 7.1e-08 32.5 0.0 0.0012 18.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXX74332.1 - 2.2e-07 31.0 0.0 0.0029 17.7 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KXX74332.1 - 2.2e-07 31.6 10.2 0.0012 19.4 0.1 3.3 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.6 KXX74332.1 - 3e-07 30.8 0.1 0.014 15.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXX74332.1 - 8.8e-07 29.3 0.0 0.023 15.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 KXX74332.1 - 7.5e-06 26.1 0.0 0.00066 19.8 0.0 2.9 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 KXX74332.1 - 9.5e-06 24.8 0.9 0.11 11.5 0.0 3.1 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KXX74332.1 - 1.3e-05 25.7 0.0 0.23 12.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KXX74332.1 - 1.4e-05 25.0 0.1 0.07 12.8 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain AAA_16 PF13191.6 KXX74332.1 - 1.6e-05 25.4 1.3 0.21 11.9 0.0 4.2 5 0 0 5 5 4 1 AAA ATPase domain AAA PF00004.29 KXX74332.1 - 2e-05 25.0 0.3 0.48 10.9 0.0 4.4 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX74332.1 - 5.4e-05 23.4 0.0 0.57 10.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain PduV-EutP PF10662.9 KXX74332.1 - 0.00011 22.0 0.0 0.082 12.7 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 KXX74332.1 - 0.00015 21.4 0.0 0.12 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXX74332.1 - 0.00016 22.0 0.0 1.3 9.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Adaptin_N PF01602.20 KXX74332.1 - 0.00026 19.7 2.1 0.00047 18.9 2.1 1.4 1 0 0 1 1 1 1 Adaptin N terminal region AAA_24 PF13479.6 KXX74332.1 - 0.00064 19.5 0.1 1.7 8.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KXX74332.1 - 0.00069 19.6 0.1 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ParcG PF10274.9 KXX74332.1 - 0.00069 19.8 0.8 4.9 7.2 0.1 3.2 1 1 2 3 3 3 0 Parkin co-regulated protein DUF87 PF01935.17 KXX74332.1 - 0.0012 19.0 1.6 0.9 9.6 0.0 3.9 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_30 PF13604.6 KXX74332.1 - 0.0014 18.4 0.4 3.8 7.2 0.0 3.6 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 KXX74332.1 - 0.0015 18.5 0.0 2.5 8.0 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain G-alpha PF00503.20 KXX74332.1 - 0.0019 17.5 0.0 1.4 8.0 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit AAA_14 PF13173.6 KXX74332.1 - 0.0023 18.0 0.0 5.3 7.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KXX74332.1 - 0.0025 17.4 0.1 3.3 7.3 0.0 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 KXX74332.1 - 0.0057 16.9 0.0 1.1 9.6 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 KXX74332.1 - 0.0071 16.1 0.0 5.6 6.7 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 KXX74332.1 - 0.0084 15.3 0.1 0.38 9.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 KXX74332.1 - 0.0087 16.3 0.0 11 6.3 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase HEAT PF02985.22 KXX74332.1 - 0.012 15.8 0.7 7.2 7.2 0.1 4.2 4 0 0 4 4 3 0 HEAT repeat ATP_bind_1 PF03029.17 KXX74332.1 - 0.013 15.3 0.2 7.8 6.2 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KXX74332.1 - 0.013 15.4 0.0 3.7 7.4 0.0 3.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 KXX74332.1 - 0.016 14.9 0.2 7.9 6.1 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CLP1_P PF16575.5 KXX74332.1 - 0.016 15.0 0.9 0.8 9.5 0.0 2.8 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PRK PF00485.18 KXX74332.1 - 0.016 14.9 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 KXX74332.1 - 0.028 13.7 0.4 4.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Septin AAA_7 PF12775.7 KXX74332.1 - 0.034 13.7 0.1 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 KXX74332.1 - 0.051 13.3 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 KXX74332.1 - 0.057 13.3 0.1 15 5.4 0.1 2.9 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 KXX74332.1 - 0.061 12.6 0.1 11 5.2 0.0 2.9 2 0 0 2 2 2 0 Zeta toxin HEAT_2 PF13646.6 KXX74332.1 - 0.065 13.6 8.7 0.55 10.7 4.5 3.5 1 1 3 4 4 4 0 HEAT repeats T2SSE PF00437.20 KXX74332.1 - 0.071 12.2 0.1 8.1 5.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.13 KXX74332.1 - 0.1 11.7 0.0 13 4.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 KXX74332.1 - 0.12 11.9 0.2 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Mg_chelatase PF01078.21 KXX74332.1 - 0.13 11.6 0.1 8.8 5.6 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.6 KXX74332.1 - 0.36 9.4 6.6 2.8 6.4 0.0 3.9 4 1 0 4 4 4 0 AAA domain HEAT_EZ PF13513.6 KXX74332.1 - 1.3 9.7 9.5 19 5.9 1.1 4.7 5 0 0 5 5 3 0 HEAT-like repeat Ank_2 PF12796.7 KXX74333.1 - 2.6e-45 152.9 0.5 6.1e-08 33.2 0.0 7.6 5 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX74333.1 - 3e-36 119.3 18.5 2.5e-07 30.5 0.0 13.0 14 1 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.6 KXX74333.1 - 2.5e-33 114.0 10.4 8.7e-05 23.0 0.0 9.4 9 2 2 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 KXX74333.1 - 6e-33 111.8 21.5 3.8e-07 30.2 0.0 10.9 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KXX74333.1 - 1.9e-31 107.7 5.5 2.5e-07 30.9 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeats (many copies) F-box-like PF12937.7 KXX74333.1 - 0.034 14.0 1.0 0.13 12.2 0.6 2.1 2 0 0 2 2 2 0 F-box-like SAS4 PF15460.6 KXX74334.1 - 6.1e-33 112.9 0.5 1.4e-32 111.7 0.2 1.8 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 SDA1 PF05285.12 KXX74334.1 - 0.003 17.1 8.3 0.0059 16.1 8.3 1.4 1 0 0 1 1 1 1 SDA1 DUF4719 PF15843.5 KXX74334.1 - 5.1 7.2 8.6 1.6 8.8 3.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4719) BTB PF00651.31 KXX74335.1 - 6.9e-08 32.7 0.0 2.5e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain ANAPC_CDC26 PF10471.9 KXX74338.1 - 7.8e-12 45.9 0.4 7.8e-12 45.9 0.4 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex APC subunit CDC26 DUF4677 PF15726.5 KXX74338.1 - 0.0043 17.2 1.2 0.0083 16.3 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4677) K_channel_TID PF07941.11 KXX74338.1 - 0.0085 16.5 12.4 0.0085 16.5 12.4 4.6 3 1 0 3 3 3 2 Potassium channel Kv1.4 tandem inactivation domain DUF4407 PF14362.6 KXX74338.1 - 1.4 8.2 5.4 2 7.7 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myc_N PF01056.18 KXX74338.1 - 1.8 8.4 6.9 0.22 11.4 0.6 2.1 1 1 1 2 2 2 0 Myc amino-terminal region GREB1 PF15782.5 KXX74338.1 - 4 4.4 3.9 5.4 4.0 3.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_M1_N PF17900.1 KXX74339.1 - 2.8e-06 27.7 0.2 0.034 14.3 0.0 2.9 3 0 0 3 3 3 2 Peptidase M1 N-terminal domain HEAT PF02985.22 KXX74339.1 - 0.15 12.4 0.1 34 5.1 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat Aldedh PF00171.22 KXX74340.1 - 6.4e-135 450.2 0.0 7.8e-135 449.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HATPase_c PF02518.26 KXX74341.1 - 2.5e-29 102.1 0.1 4.5e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXX74341.1 - 1.1e-20 73.8 0.2 2.2e-20 72.9 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 KXX74341.1 - 1.8e-20 73.0 0.1 1.1e-19 70.5 0.2 2.3 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 KXX74341.1 - 4e-20 71.6 0.1 1.1e-19 70.2 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KXX74341.1 - 1.3e-19 70.5 0.1 2.9e-08 33.9 0.0 4.6 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 KXX74341.1 - 1.4e-15 57.4 0.0 6.9e-08 32.7 0.0 4.4 4 0 0 4 4 4 3 PAS domain PAS PF00989.25 KXX74341.1 - 5.4e-15 55.4 0.0 0.0015 18.5 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 KXX74341.1 - 1.3e-05 25.0 0.1 0.0066 16.4 0.0 3.7 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 KXX74341.1 - 0.0023 17.8 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MLTR_LBD PF17765.1 KXX74341.1 - 0.0056 16.8 0.7 0.084 13.0 0.1 2.6 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain PAS_11 PF14598.6 KXX74341.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain GRIP PF01465.20 KXX74341.1 - 0.15 12.0 0.1 0.97 9.4 0.0 2.3 2 0 0 2 2 2 0 GRIP domain Asp PF00026.23 KXX74343.1 - 2e-68 231.2 0.0 2.3e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX74343.1 - 8.1e-11 42.5 0.4 4.6e-05 23.7 0.0 2.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KXX74343.1 - 0.045 13.5 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal WLM PF08325.10 KXX74344.1 - 1.6e-33 116.4 0.0 2.1e-33 116.0 0.0 1.5 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KXX74344.1 - 1.1e-05 24.6 0.8 1.9e-05 23.9 0.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KXX74344.1 - 0.00033 20.8 0.1 0.00065 19.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 AMP-binding PF00501.28 KXX74346.1 - 5.5e-71 239.4 0.0 6.6e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX74346.1 - 2.5e-19 70.0 0.1 7.7e-19 68.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OKR_DC_1_N PF03709.15 KXX74346.1 - 0.064 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain GFA PF04828.14 KXX74347.1 - 0.016 15.5 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_1 PF00232.18 KXX74348.1 - 3.4e-152 507.0 0.0 4.1e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AID PF18767.1 KXX74348.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Activation induced deaminase Xpo1 PF08389.12 KXX74349.1 - 2e-39 135.0 2.6 3.6e-38 131.0 0.0 3.7 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 KXX74349.1 - 0.0055 16.8 1.4 3.3 8.2 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KXX74349.1 - 0.19 12.3 1.0 77 4.0 0.1 4.7 4 1 1 5 5 5 0 HEAT-like repeat POB3_N PF17292.2 KXX74350.1 - 6.9e-31 106.5 0.8 2.5e-29 101.5 0.2 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KXX74350.1 - 1.3e-29 101.9 0.1 1e-28 99.0 0.0 2.5 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KXX74350.1 - 6e-23 81.1 0.0 3.3e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like KIX_2 PF16987.5 KXX74351.1 - 0.00022 21.1 0.6 0.00022 21.1 0.6 2.7 2 0 0 2 2 2 1 KIX domain Peptidase_M18 PF02127.15 KXX74352.1 - 1.3e-174 581.0 0.0 1.6e-174 580.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KXX74352.1 - 6.4e-05 22.1 0.0 0.00041 19.5 0.0 2.2 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Pkinase PF00069.25 KXX74353.1 - 3.7e-65 219.9 0.0 4.5e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74353.1 - 9.1e-30 103.8 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX74353.1 - 3e-06 26.8 0.0 4.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXX74353.1 - 0.00034 20.6 0.2 0.026 14.5 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXX74353.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KXX74353.1 - 0.022 13.5 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RabGAP-TBC PF00566.18 KXX74354.1 - 1.3e-45 155.8 0.0 1.9e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KXX74354.1 - 5.7e-06 25.8 0.4 0.0048 16.7 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXX74354.1 - 0.00079 18.8 1.1 0.46 10.2 0.8 3.4 3 0 0 3 3 3 2 EF hand GRAM PF02893.20 KXX74354.1 - 0.0039 17.1 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 KXX74354.1 - 0.0074 16.7 0.6 0.12 12.9 0.4 2.9 1 1 1 2 2 2 2 EF-hand domain pair WSC PF01822.19 KXX74355.1 - 3.8e-18 65.5 16.1 8.1e-17 61.2 3.9 4.1 4 0 0 4 4 4 3 WSC domain K_channel_TID PF07941.11 KXX74355.1 - 0.43 11.1 2.3 0.34 11.4 0.4 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain UPF0139 PF03669.13 KXX74357.1 - 5.6e-09 35.8 0.0 6.8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) HET PF06985.11 KXX74358.1 - 1.1e-24 87.4 0.0 2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) S1-P1_nuclease PF02265.16 KXX74359.1 - 3.6e-75 253.1 0.0 4.1e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.14 KXX74360.1 - 7.4e-37 124.9 13.9 7.7e-20 70.4 0.4 2.9 3 1 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KXX74360.1 - 0.02 15.7 0.0 1.2 10.0 0.0 2.4 2 0 0 2 2 2 0 ER lumen protein retaining receptor Med12 PF09497.10 KXX74361.1 - 2.2e-29 101.5 0.3 5e-29 100.4 0.3 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 TAN PF11640.8 KXX74361.1 - 0.00044 20.4 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Med12-LCEWAV PF12145.8 KXX74361.1 - 0.014 14.3 0.0 0.043 12.7 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic Mediator 12 subunit domain LEA_6 PF10714.9 KXX74361.1 - 0.89 9.7 2.5 16 5.7 0.1 2.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Methyltransf_23 PF13489.6 KXX74362.1 - 1.8e-15 57.2 0.0 2.6e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74362.1 - 7.9e-08 32.9 0.0 2e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74362.1 - 3.6e-06 26.9 0.0 0.046 13.5 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74362.1 - 3.9e-06 27.4 0.0 6.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXX74362.1 - 0.0014 17.9 0.0 0.0069 15.7 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KXX74362.1 - 0.0045 17.7 0.0 0.022 15.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX74362.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KXX74362.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) WSC PF01822.19 KXX74363.1 - 0.0082 16.3 1.8 0.027 14.7 1.8 2.0 1 0 0 1 1 1 1 WSC domain FAD_binding_4 PF01565.23 KXX74364.1 - 7.8e-16 58.1 1.0 1.1e-15 57.6 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXX74364.1 - 8.3e-11 42.2 0.6 4.4e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Dehydratase_LU PF02286.15 KXX74365.1 - 0.0039 15.8 0.2 0.0055 15.3 0.2 1.1 1 0 0 1 1 1 1 Dehydratase large subunit ANAPC4_WD40 PF12894.7 KXX74366.1 - 0.0011 19.2 0.0 0.37 11.1 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX74366.1 - 0.029 15.2 2.8 3.2 8.8 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KXX74366.1 - 0.047 14.2 0.4 0.21 12.1 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 KXX74366.1 - 0.062 13.2 0.0 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat EccE PF11203.8 KXX74367.1 - 0.064 13.6 2.5 0.4 11.0 1.5 2.4 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE QSregVF PF13652.6 KXX74367.1 - 0.089 12.8 0.8 0.15 12.1 0.8 1.4 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor PEPCK_ATP PF01293.20 KXX74368.1 - 8.2e-217 720.4 0.0 9.9e-217 720.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KXX74368.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXX74368.1 - 0.19 11.9 0.1 0.36 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Tyrosinase PF00264.20 KXX74369.1 - 3.8e-46 158.1 0.1 4.9e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.10 KXX74369.1 - 0.16 12.6 0.0 0.32 11.6 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain p450 PF00067.22 KXX74370.1 - 8.5e-64 216.0 0.0 1.1e-63 215.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CK_II_beta PF01214.18 KXX74371.1 - 7.1e-75 250.8 0.0 1.2e-74 250.1 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PTPRCAP PF15713.5 KXX74371.1 - 0.11 12.8 5.9 4.1 7.7 2.2 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Spt5_N PF11942.8 KXX74371.1 - 0.13 13.3 10.0 0.095 13.7 4.3 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 KXX74371.1 - 0.15 10.6 1.3 0.24 9.9 1.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 KXX74371.1 - 0.84 10.1 10.6 7.6 7.0 0.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCIP PF13324.6 KXX74371.1 - 2.1 7.9 4.0 0.79 9.3 1.1 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KXX74371.1 - 9.9 5.4 9.0 3.3 7.0 4.7 2.0 2 0 0 2 2 2 0 NOA36 protein Cupin_8 PF13621.6 KXX74372.1 - 2.7e-17 63.4 0.0 1.2e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXX74372.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 KXX74372.1 - 0.096 12.4 2.3 0.19 11.5 0.0 2.6 3 0 0 3 3 3 0 Cupin domain JmjC PF02373.22 KXX74372.1 - 0.13 12.6 0.0 2.7 8.5 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase DUF924 PF06041.11 KXX74373.1 - 7.2e-24 84.9 0.0 1e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Mito_carr PF00153.27 KXX74374.1 - 3e-22 78.3 1.7 4.6e-14 52.1 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein NPR3 PF03666.13 KXX74374.1 - 0.006 15.4 0.4 0.008 15.0 0.4 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Spt20 PF12090.8 KXX74374.1 - 0.38 10.3 6.1 0.58 9.7 6.1 1.2 1 0 0 1 1 1 0 Spt20 family SAGA-Tad1 PF12767.7 KXX74374.1 - 0.43 10.3 5.1 0.19 11.5 2.4 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF702 PF05142.12 KXX74374.1 - 1 9.9 6.3 0.2 12.1 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Complex1_LYR PF05347.15 KXX74375.1 - 0.013 15.5 2.2 0.03 14.4 0.1 2.3 2 0 0 2 2 2 0 Complex 1 protein (LYR family) AAA PF00004.29 KXX74376.1 - 3.3e-20 72.9 0.0 6.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX74376.1 - 0.0028 17.9 2.6 0.031 14.5 0.0 2.6 2 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KXX74376.1 - 0.0053 16.7 0.1 0.02 14.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXX74376.1 - 0.05 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX74376.1 - 0.052 13.9 0.2 0.052 13.9 0.2 2.7 2 1 1 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 KXX74376.1 - 0.073 13.6 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KXX74376.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KXX74376.1 - 0.079 12.5 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 KXX74376.1 - 0.12 12.0 0.0 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Chs7 PF12271.8 KXX74377.1 - 1.7e-109 365.6 0.6 2e-109 365.4 0.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Cytochrom_B561 PF03188.16 KXX74378.1 - 7e-17 61.8 6.0 7e-17 61.8 6.0 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXX74378.1 - 0.0092 16.1 12.3 1.7 8.8 0.1 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF4079) DUF588 PF04535.12 KXX74378.1 - 0.013 15.3 0.9 0.021 14.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) SLATT_3 PF18184.1 KXX74378.1 - 0.26 11.4 2.5 9.6 6.3 0.4 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 DUF2162 PF09930.9 KXX74378.1 - 0.33 10.3 8.5 0.11 11.9 3.0 2.2 1 1 1 2 2 2 0 Predicted transporter (DUF2162) Allantoicase PF03561.15 KXX74379.1 - 9.6e-93 307.7 0.1 1.9e-47 160.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Acetyltransf_3 PF13302.7 KXX74380.1 - 2.1e-08 34.9 0.0 2.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX74380.1 - 5.7e-06 26.6 0.0 8.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ilar_coat PF01787.16 KXX74380.1 - 0.0061 16.4 0.0 0.0081 16.0 0.0 1.1 1 0 0 1 1 1 1 Ilarvirus coat protein HET PF06985.11 KXX74381.1 - 6.5e-28 97.9 0.0 1.2e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EcKinase PF02958.20 KXX74382.1 - 1.1e-16 61.1 0.0 1.6e-11 44.1 0.4 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 KXX74382.1 - 3e-08 33.0 0.1 4.9e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 KXX74382.1 - 3.2e-08 33.8 2.0 4.8e-08 33.2 2.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DIL PF01843.19 KXX74383.1 - 1e-32 112.5 0.8 2.1e-32 111.5 0.8 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KXX74383.1 - 6.4e-14 52.3 0.0 2.4e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX74383.1 - 3.7e-13 49.7 0.1 1.6e-07 31.7 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX74383.1 - 7.7e-11 42.0 0.1 2.3e-06 27.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXX74383.1 - 2.9e-08 33.8 0.6 0.0082 16.5 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KXX74383.1 - 1.4e-06 28.2 0.1 0.28 11.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Sugar_tr PF00083.24 KXX74384.1 - 1.4e-100 337.3 16.0 1.8e-100 336.9 16.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX74384.1 - 1.4e-28 99.9 15.7 1.4e-28 99.9 15.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXX74384.1 - 6.3e-08 31.6 21.4 6.5e-07 28.3 5.6 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 KXX74384.1 - 0.011 14.6 1.8 0.017 14.0 1.8 1.3 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM p450 PF00067.22 KXX74385.1 - 2.9e-21 75.8 0.0 1.1e-20 73.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Beta_elim_lyase PF01212.21 KXX74386.1 - 3.5e-52 177.5 2.2 8.3e-28 97.5 0.1 2.0 2 0 0 2 2 2 2 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXX74386.1 - 4.1e-06 26.4 1.5 0.00013 21.4 0.1 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXX74386.1 - 8.5e-06 25.2 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXX74386.1 - 0.085 11.8 0.0 4.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V MFS_1 PF07690.16 KXX74387.1 - 8e-25 87.5 26.2 8e-25 87.5 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74387.1 - 1.9e-14 53.4 3.8 1.9e-14 53.4 3.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXX74387.1 - 0.00015 20.3 0.5 0.0014 17.1 1.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4360 PF14273.6 KXX74388.1 - 6.1e-34 117.4 0.0 7.4e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) bZIP_Maf PF03131.17 KXX74389.1 - 0.052 14.1 1.4 0.26 11.8 0.0 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Acetyltransf_7 PF13508.7 KXX74390.1 - 4.5e-06 27.0 0.0 7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX74390.1 - 9.3e-05 22.4 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX74390.1 - 0.0058 16.9 0.0 0.0082 16.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family F-box-like PF12937.7 KXX74392.1 - 0.00039 20.3 0.1 0.00075 19.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX74392.1 - 5.4 7.0 5.1 0.85 9.6 0.1 2.3 2 0 0 2 2 2 0 F-box domain FAD_binding_4 PF01565.23 KXX74393.1 - 3.4e-22 78.7 5.4 5.4e-22 78.0 5.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX74393.1 - 9.6e-12 44.8 0.3 2.6e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like ING PF12998.7 KXX74394.1 - 2.9e-07 31.0 0.0 0.00028 21.4 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXX74394.1 - 1.8e-06 27.7 7.4 3e-06 27.0 7.4 1.4 1 0 0 1 1 1 1 PHD-finger CENP-B_dimeris PF09026.10 KXX74394.1 - 0.23 11.8 4.3 0.22 12.0 1.8 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-HC5HC2H PF13771.6 KXX74394.1 - 0.31 11.3 1.5 0.71 10.2 1.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Rhomboid PF01694.22 KXX74395.1 - 9.3e-06 25.7 2.2 2.3e-05 24.4 2.2 1.7 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KXX74395.1 - 9.6e-05 22.9 0.2 0.00018 22.0 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Gly-zipper_Omp PF13488.6 KXX74395.1 - 0.012 15.6 0.6 0.58 10.2 0.1 2.5 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 KXX74395.1 - 0.14 11.9 3.6 3 7.7 0.5 2.3 2 0 0 2 2 2 0 Glycine-zipper domain Transgly_assoc PF04226.13 KXX74395.1 - 7.7 6.9 9.1 4.4 7.6 0.2 3.3 3 0 0 3 3 3 0 Transglycosylase associated protein Uds1 PF15456.6 KXX74396.1 - 1.4e-40 138.5 9.2 1.4e-40 138.5 9.2 7.7 4 3 2 6 6 6 1 Up-regulated During Septation HMG_box PF00505.19 KXX74396.1 - 0.35 11.3 2.5 1.2 9.6 2.5 2.0 1 0 0 1 1 1 0 HMG (high mobility group) box Baculo_PEP_C PF04513.12 KXX74396.1 - 2.2 8.3 35.5 0.37 10.8 1.5 6.8 6 2 0 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus TAF4 PF05236.14 KXX74397.1 - 9.5e-05 22.3 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 KXX74398.1 - 2.4e-87 292.0 0.0 3.3e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KXX74398.1 - 1.8e-30 105.4 0.0 5.6e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KXX74398.1 - 4.6e-18 65.4 0.1 7.7e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KXX74398.1 - 7.4e-18 65.3 0.7 1.3e-17 64.4 0.7 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KXX74398.1 - 5.4e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KXX74398.1 - 4.1e-06 26.5 0.9 2e-05 24.2 0.7 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXX74398.1 - 6.6e-06 26.1 0.1 1.7e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CHB_HEX_C PF03174.13 KXX74398.1 - 0.057 13.4 0.0 0.81 9.7 0.0 2.8 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain TAF4 PF05236.14 KXX74399.1 - 4.7e-21 75.8 0.4 6.8e-21 75.2 0.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family LEA_3 PF03242.13 KXX74399.1 - 0.054 14.2 2.7 0.52 11.1 1.5 3.0 3 1 0 3 3 3 0 Late embryogenesis abundant protein Tcp11 PF05794.13 KXX74400.1 - 2.9e-108 362.8 0.0 3.5e-108 362.5 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 V_ATPase_I PF01496.19 KXX74401.1 - 0 1043.2 0.0 0 1043.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KXX74401.1 - 0.08 12.9 2.0 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF1664 PF07889.12 KXX74401.1 - 0.1 12.7 2.1 8.3 6.5 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SesA PF17107.5 KXX74401.1 - 0.12 12.5 1.1 1.4 9.2 0.1 2.6 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF639 PF04842.12 KXX74401.1 - 0.15 11.5 0.6 0.36 10.2 0.6 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3584 PF12128.8 KXX74401.1 - 0.29 8.6 5.0 0.12 9.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Nup54 PF13874.6 KXX74401.1 - 0.32 11.1 2.1 4.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 KXX74401.1 - 0.32 9.8 2.7 3.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 KXX74401.1 - 0.44 10.1 10.0 1.1 8.7 0.5 2.6 2 1 0 2 2 2 0 Intermediate filament protein CLZ PF16526.5 KXX74401.1 - 0.46 10.9 5.1 15 6.0 0.4 2.8 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SKA2 PF16740.5 KXX74401.1 - 0.49 10.2 2.1 26 4.7 0.2 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 KXX74401.1 - 0.57 10.0 7.2 0.5 10.2 0.1 3.2 3 0 0 3 3 3 0 Septum formation initiator Laminin_II PF06009.12 KXX74401.1 - 0.94 9.5 5.1 13 5.8 1.2 2.3 2 0 0 2 2 2 0 Laminin Domain II DHR10 PF18595.1 KXX74401.1 - 1.1 9.4 7.5 2.4 8.2 1.9 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain LXG PF04740.12 KXX74401.1 - 1.5 8.5 4.0 10 5.8 0.3 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DASH_Dad2 PF08654.10 KXX74401.1 - 1.8 9.0 3.8 19 5.7 0.8 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad2 Snapin_Pallidin PF14712.6 KXX74401.1 - 4.3 7.8 5.3 23 5.5 0.8 2.9 2 1 0 2 2 2 0 Snapin/Pallidin Prefoldin_2 PF01920.20 KXX74401.1 - 5.5 7.0 6.5 23 5.0 2.9 2.8 2 1 0 2 2 2 0 Prefoldin subunit DUF1515 PF07439.11 KXX74401.1 - 6.5 6.8 7.6 1.7 8.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) F-box-like PF12937.7 KXX74402.1 - 0.0041 17.0 0.1 0.012 15.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KXX74402.1 - 0.018 15.1 1.6 13 6.1 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Prenyltransf PF01255.19 KXX74403.1 - 2e-83 279.3 0.0 1.2e-82 276.8 0.0 1.8 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Zn_clus PF00172.18 KXX74404.1 - 3e-07 30.5 9.0 3e-07 30.5 9.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KXX74405.1 - 1.3e-75 254.2 0.0 1.7e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74405.1 - 1.8e-37 129.0 0.0 2.6e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KXX74405.1 - 2.1e-20 73.3 2.6 4.3e-17 62.6 2.6 3.2 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KXX74405.1 - 1.5e-15 57.0 0.3 3.5e-15 55.8 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KXX74405.1 - 2.3e-05 23.9 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXX74405.1 - 0.0008 19.1 0.2 0.0017 18.0 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXX74405.1 - 0.0039 16.2 0.3 0.007 15.3 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KXX74405.1 - 0.0089 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KXX74405.1 - 0.069 13.1 1.0 0.31 10.9 0.5 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Hydantoinase_B PF02538.14 KXX74406.1 - 1.1e-219 730.2 0.6 1.7e-219 729.5 0.6 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXX74406.1 - 2.4e-104 348.7 1.1 3.8e-104 348.0 1.1 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXX74406.1 - 6.9e-14 51.9 3.9 3.8e-13 49.5 0.4 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF92 PF01940.16 KXX74408.1 - 1.5e-88 296.2 2.7 1.9e-88 295.9 2.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Fungal_trans PF04082.18 KXX74409.1 - 0.0006 18.9 0.4 0.0016 17.6 0.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain FCP1_C PF09309.10 KXX74410.1 - 0.05 13.5 1.6 0.059 13.2 0.3 1.7 2 0 0 2 2 2 0 FCP1, C-terminal WD40 PF00400.32 KXX74411.1 - 1.3e-18 67.0 16.5 3.7e-06 27.6 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74411.1 - 3.5e-06 27.2 0.1 0.15 12.4 0.0 4.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX74411.1 - 0.0089 14.7 0.1 1.4 7.5 0.0 3.0 2 1 0 3 3 3 2 Nucleoporin Nup120/160 YpzI PF14140.6 KXX74412.1 - 5.4 6.9 11.3 16 5.4 0.2 4.2 4 0 0 4 4 4 0 YpzI-like protein MARVEL PF01284.23 KXX74413.1 - 7.3e-18 65.0 17.2 8.8e-18 64.7 17.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.8 KXX74413.1 - 0.12 12.1 3.5 0.18 11.6 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Pox_A14 PF05767.12 KXX74413.1 - 0.44 10.7 3.1 0.4 10.8 0.2 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 ABC2_membrane_5 PF13346.6 KXX74413.1 - 0.58 9.7 6.2 0.74 9.3 6.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF5632 PF18646.1 KXX74414.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5632) DUF4449 PF14613.6 KXX74415.1 - 2.6e-05 24.4 0.0 2.6e-05 24.4 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) ALMS_repeat PF18727.1 KXX74415.1 - 0.1 12.5 0.7 0.7 9.8 0.1 2.5 2 0 0 2 2 2 0 Alstrom syndrome repeat Patatin PF01734.22 KXX74416.1 - 4.1e-14 53.2 0.0 1.4e-13 51.5 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.8 KXX74417.1 - 1.2e-12 47.4 0.0 2.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX74417.1 - 0.00011 22.2 14.8 0.00021 21.3 14.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.12 KXX74418.1 - 4.9e-48 163.7 0.0 1.4e-47 162.2 0.0 1.5 1 1 0 1 1 1 1 Autophagy protein Apg5 Zn_clus PF00172.18 KXX74419.1 - 6e-07 29.5 13.6 9.2e-07 28.9 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KXX74420.1 - 2.7e-27 95.8 0.0 3.7e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74420.1 - 5.1e-14 52.2 0.0 6.8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX74420.1 - 9.3e-07 28.0 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EMP24_GP25L PF01105.24 KXX74421.1 - 1.3e-51 175.2 0.0 1.4e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5631 PF18645.1 KXX74422.1 - 0.42 11.0 11.2 0.97 9.9 0.4 4.0 2 1 2 4 4 4 0 Family of unknown function (DUF5631) TraQ PF09679.10 KXX74422.1 - 4.8 7.2 4.7 1.8 8.5 0.3 2.7 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF745 PF05335.13 KXX74422.1 - 6.6 6.4 70.3 0.047 13.4 30.3 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Mac PF12464.8 KXX74423.1 - 7e-13 48.6 0.1 1.9e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KXX74423.1 - 7.8e-13 47.6 15.7 1.1e-07 31.2 0.4 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 KXX74423.1 - 4.4e-09 36.3 8.2 9.1e-09 35.3 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.6 KXX74423.1 - 1.3e-07 31.2 15.6 0.0025 17.5 0.1 3.4 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Spt20 PF12090.8 KXX74423.1 - 0.01 15.5 16.1 0.025 14.2 16.1 1.6 1 0 0 1 1 1 0 Spt20 family SANT_DAMP1_like PF16282.5 KXX74424.1 - 1.3e-31 108.7 0.9 2.2e-31 107.9 0.9 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Adap_comp_sub PF00928.21 KXX74426.1 - 4.3e-73 245.9 0.0 5.7e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Glyco_hydro_6 PF01341.17 KXX74427.1 - 1.3e-100 337.1 0.1 1.7e-100 336.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF4536 PF15055.6 KXX74428.1 - 4.8e-08 33.1 0.6 7e-08 32.6 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) OST3_OST6 PF04756.13 KXX74429.1 - 2e-104 349.1 0.0 2.5e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KXX74429.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin CPBP PF02517.16 KXX74429.1 - 0.13 12.6 3.2 0.31 11.4 3.0 1.6 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease DUF4267 PF14087.6 KXX74431.1 - 1.7e-15 57.1 3.7 1.9e-15 56.9 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Peptidase_M28 PF04389.17 KXX74432.1 - 2.4e-25 89.4 0.1 4.5e-17 62.4 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M28 Peptidase_M20 PF01546.28 KXX74432.1 - 0.0011 18.8 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SF1-HH PF16275.5 KXX74434.1 - 3.5e-44 149.7 1.4 8e-44 148.6 1.4 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KXX74434.1 - 1.4e-11 43.9 12.6 1.7e-05 24.7 1.7 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KXX74434.1 - 1.8e-08 34.1 0.1 3.8e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KXX74434.1 - 5.5e-06 26.3 7.3 0.002 18.1 3.6 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KXX74434.1 - 0.002 18.0 8.7 0.08 12.8 0.5 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KXX74434.1 - 0.0035 17.1 6.5 0.45 10.3 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KXX74434.1 - 0.0083 15.9 1.5 0.0083 15.9 1.5 2.4 2 0 0 2 2 2 1 Zinc knuckle BBE PF08031.12 KXX74435.1 - 1.1e-10 41.4 0.1 2.6e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FKBP_C PF00254.28 KXX74436.1 - 8.6e-38 128.6 0.0 1.1e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Flavin_Reduct PF01613.18 KXX74437.1 - 1.1e-32 113.2 0.0 1.4e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.18 KXX74438.1 - 0.00017 21.7 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Vps5 PF09325.10 KXX74439.1 - 7.4e-88 294.1 7.8 7.4e-88 294.1 7.8 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KXX74439.1 - 2.9e-26 91.7 0.3 5.5e-26 90.8 0.1 1.6 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KXX74439.1 - 0.0005 19.8 6.7 0.0026 17.5 3.6 2.5 1 1 1 2 2 2 1 BAR domain of APPL family Lipase_GDSL PF00657.22 KXX74439.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase BAR_2 PF10455.9 KXX74439.1 - 0.013 14.6 6.1 0.023 13.8 5.6 1.6 2 1 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.9 KXX74439.1 - 0.019 14.4 0.7 0.12 11.8 0.6 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.13 KXX74439.1 - 0.1 12.2 3.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Arfaptin-like domain HBM PF16591.5 KXX74439.1 - 0.15 11.5 11.6 2.3 7.5 0.3 2.5 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF713 PF05218.14 KXX74439.1 - 0.23 11.2 4.7 0.26 11.0 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF713) BAR PF03114.18 KXX74439.1 - 1.7 8.2 10.5 3.2 7.3 9.4 2.1 2 1 0 2 2 2 0 BAR domain MBOAT PF03062.19 KXX74440.1 - 9.6e-40 137.0 14.7 3.7e-38 131.8 13.6 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 KXX74441.1 - 7.7e-43 146.7 0.0 1.7e-41 142.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74441.1 - 9.9e-27 93.8 0.0 1.7e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX74441.1 - 0.015 14.1 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase HSP90 PF00183.18 KXX74442.1 - 2.7e-224 745.9 31.3 3.7e-224 745.4 31.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KXX74442.1 - 2.4e-16 60.3 0.2 4.4e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXX74442.1 - 9.9e-10 38.4 0.3 9.9e-10 38.4 0.3 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 KXX74442.1 - 0.21 11.6 6.8 0.43 10.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Cofac_haem_bdg PF04187.13 KXX74442.1 - 0.31 11.0 1.2 1.4 8.9 0.0 2.6 2 1 1 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN LOH1CR12 PF10158.9 KXX74442.1 - 0.4 10.7 2.8 0.29 11.2 0.2 2.1 2 0 0 2 2 2 0 Tumour suppressor protein GST_N_3 PF13417.6 KXX74443.1 - 6.8e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXX74443.1 - 8.4e-14 51.7 0.0 1.8e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXX74443.1 - 9.7e-12 45.0 0.0 2.3e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX74443.1 - 1.6e-11 44.3 0.0 4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXX74443.1 - 3.6e-10 40.0 0.0 7.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX74443.1 - 2.3e-06 27.5 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATPgrasp_YheCD PF14398.6 KXX74443.1 - 0.093 12.0 0.4 0.7 9.1 0.1 2.4 2 1 1 3 3 3 0 YheC/D like ATP-grasp Med11 PF10280.9 KXX74444.1 - 7.7e-44 149.5 8.5 2.2e-43 148.0 8.5 1.7 1 1 0 1 1 1 1 Mediator complex protein Spt20 PF12090.8 KXX74444.1 - 0.068 12.8 8.5 0.1 12.2 8.5 1.3 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 KXX74444.1 - 0.08 11.9 2.4 0.098 11.6 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 KXX74444.1 - 0.48 11.4 2.5 0.73 10.8 1.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 KXX74444.1 - 9.1 6.2 15.0 11 5.8 15.0 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIID_NTD2 PF04494.15 KXX74445.1 - 8.5e-42 142.5 0.1 1.2e-41 142.0 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 KXX74445.1 - 6.3e-39 131.3 24.4 3.4e-07 30.9 0.2 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74445.1 - 2e-13 50.4 0.4 0.073 13.4 0.0 5.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXX74445.1 - 0.00023 21.1 0.1 0.0089 15.9 0.0 2.9 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KXX74445.1 - 0.0057 16.6 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 KXX74445.1 - 0.0064 15.5 1.3 1.3 7.9 0.6 3.5 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXX74445.1 - 0.023 13.3 0.8 2.9 6.4 0.1 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXX74445.1 - 0.18 10.5 0.0 14 4.2 0.0 3.1 3 1 1 4 4 4 0 Nup133 N terminal like PAN_4 PF14295.6 KXX74446.1 - 1.7e-06 27.9 0.2 3.1e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 PAN domain MANEC PF07502.14 KXX74446.1 - 0.043 14.1 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 MANEC domain PAN_1 PF00024.26 KXX74446.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 PAN domain Beta-lactamase PF00144.24 KXX74447.1 - 6.5e-39 134.1 0.0 9.7e-38 130.2 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase F-box-like PF12937.7 KXX74448.1 - 2.4e-07 30.5 0.2 2.1e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 KXX74448.1 - 0.027 14.2 0.2 0.18 11.6 0.3 2.4 2 1 0 2 2 2 0 Leucine rich repeat F-box PF00646.33 KXX74448.1 - 0.031 14.2 1.4 0.17 11.8 1.4 2.3 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KXX74448.1 - 3.2 8.3 8.1 51 4.5 1.1 4.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) APH PF01636.23 KXX74450.1 - 4.6e-13 49.7 0.1 9.7e-13 48.6 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXX74450.1 - 0.0012 18.2 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXX74450.1 - 0.022 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CBM_19 PF03427.13 KXX74451.1 - 0.57 10.2 8.6 2.1 8.4 8.6 2.0 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) SPX PF03105.19 KXX74452.1 - 0.065 13.1 17.5 0.087 12.7 17.5 1.1 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 KXX74452.1 - 0.079 12.9 11.8 0.12 12.4 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 KXX74452.1 - 4.8 6.3 19.3 7 5.7 19.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein LUC7 PF03194.15 KXX74453.1 - 1.7e-67 227.7 0.1 2.1e-67 227.4 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 KXX74453.1 - 0.0087 15.2 0.4 0.012 14.7 0.4 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Occludin_ELL PF07303.13 KXX74453.1 - 0.012 16.3 0.4 0.069 13.9 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain Bcr-Abl_Oligo PF09036.10 KXX74453.1 - 0.059 13.4 0.3 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DHR10 PF18595.1 KXX74453.1 - 0.14 12.2 1.6 0.49 10.5 0.1 2.2 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Gpi16 PF04113.14 KXX74454.1 - 3.8e-244 811.3 0.0 4.7e-244 811.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF3716 PF12511.8 KXX74455.1 - 4.6e-15 55.4 4.8 4.6e-15 55.4 4.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) Nuc_deoxyri_tr2 PF15891.5 KXX74457.1 - 6e-36 123.0 0.0 6e-35 119.8 0.0 2.0 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase like Sushi PF00084.20 KXX74457.1 - 0.024 15.3 0.1 0.05 14.2 0.1 1.5 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) DUF434 PF04256.12 KXX74457.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Abhydrolase_4 PF08386.10 KXX74459.1 - 1.6e-21 76.3 0.0 3.2e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXX74459.1 - 1.5e-19 70.6 0.0 4.4e-16 59.3 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold adh_short PF00106.25 KXX74460.1 - 8e-07 28.7 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX74460.1 - 0.00022 20.9 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Esterase_phd PF10503.9 KXX74461.1 - 5.8e-07 29.2 0.1 2e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KXX74461.1 - 5e-06 26.5 0.0 7.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXX74461.1 - 1.4e-05 24.6 0.1 2.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXX74461.1 - 1.9e-05 24.5 0.1 5.5e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KXX74461.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 KXX74461.1 - 0.068 12.7 0.1 0.18 11.3 0.0 1.6 1 1 1 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXX74461.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 KXX74462.1 - 1.4e-17 64.0 0.0 1.4e-10 41.0 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74462.1 - 1.8e-05 24.2 0.0 0.15 11.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Glyco_hydro_3_C PF01915.22 KXX74463.1 - 2.9e-35 122.1 0.0 4.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX74463.1 - 7.8e-33 114.2 0.0 1.1e-32 113.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX74463.1 - 5.2e-06 26.5 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4232 PF14016.6 KXX74463.1 - 0.36 11.0 1.8 0.62 10.2 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4232) DUF3328 PF11807.8 KXX74465.1 - 1.8e-21 76.9 0.6 8.3e-21 74.8 0.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) HET PF06985.11 KXX74466.1 - 1e-21 77.8 0.0 2.3e-21 76.7 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GRIM-19 PF06212.12 KXX74467.1 - 5.6e-22 78.1 0.0 1.3e-21 76.9 0.0 1.6 1 1 0 1 1 1 1 GRIM-19 protein NIF PF03031.18 KXX74468.1 - 1.9e-26 92.7 0.0 4.2e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KXX74468.1 - 0.00013 21.8 0.0 0.00075 19.4 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KXX74468.1 - 0.0074 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.22 KXX74468.1 - 0.022 14.6 0.0 8.4 6.3 0.0 2.9 1 1 1 2 2 2 0 Biotin-requiring enzyme DUF3606 PF12244.8 KXX74468.1 - 0.078 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) NACHT PF05729.12 KXX74469.1 - 3e-09 37.0 0.0 8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX74469.1 - 5.7e-07 30.1 0.1 3.5e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX74469.1 - 1.5e-05 25.3 0.1 0.00085 19.6 0.0 3.3 4 0 0 4 4 4 1 AAA domain SesA PF17107.5 KXX74469.1 - 0.007 16.6 0.1 0.045 13.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_29 PF13555.6 KXX74469.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ISG65-75 PF11727.8 KXX74469.1 - 0.03 13.5 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein ABC_tran PF00005.27 KXX74469.1 - 0.035 14.6 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KXX74469.1 - 0.058 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KXX74469.1 - 0.08 13.0 2.4 3 7.9 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 KXX74469.1 - 0.088 13.4 1.1 0.56 10.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXX74469.1 - 0.18 12.2 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 KXX74469.1 - 0.26 11.7 3.4 0.28 11.7 0.0 2.6 3 1 1 4 4 4 0 AAA domain CRR7 PF12095.8 KXX74469.1 - 0.57 10.7 4.8 2.5 8.6 0.2 3.4 4 0 0 4 4 2 0 Protein CHLORORESPIRATORY REDUCTION 7 NifW PF03206.14 KXX74469.1 - 2.8 8.5 6.6 2.2 8.9 0.5 3.5 4 0 0 4 4 4 0 Nitrogen fixation protein NifW Cation_ATPase_C PF00689.21 KXX74470.1 - 1.4e-44 152.0 6.7 1.7e-44 151.8 3.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXX74470.1 - 3.5e-34 117.9 0.1 3.5e-34 117.9 0.1 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXX74470.1 - 5.1e-22 77.8 0.0 1.3e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX74470.1 - 1e-10 42.2 0.1 2.6e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXX74470.1 - 0.012 15.3 0.2 4.6 6.9 0.1 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX74470.1 - 0.037 13.7 0.2 0.31 10.7 0.0 2.7 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus DUF4149 PF13664.6 KXX74470.1 - 0.12 12.6 1.6 0.57 10.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Phage_holin_1 PF04531.13 KXX74470.1 - 1.8 9.1 4.0 8.8 6.9 0.1 3.0 2 0 0 2 2 2 0 Bacteriophage holin BNR_2 PF13088.6 KXX74471.1 - 0.0017 17.7 0.7 0.093 12.0 0.1 2.1 1 1 0 2 2 2 2 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KXX74471.1 - 0.093 11.5 0.0 3.4 6.4 0.0 2.0 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, IBN_N PF03810.19 KXX74472.1 - 9.1e-16 57.5 0.5 4.1e-15 55.5 0.4 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXX74472.1 - 0.00033 20.8 1.1 0.019 15.0 0.0 3.7 4 0 0 4 4 4 1 Exportin 1-like protein tRNA-synt_1g PF09334.11 KXX74473.1 - 3.5e-09 35.9 0.0 1.2e-08 34.1 0.0 1.9 3 0 0 3 3 3 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXX74473.1 - 2.3e-05 24.4 0.3 4.3e-05 23.5 0.1 1.5 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXX74473.1 - 6.8e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 KXX74473.1 - 0.00015 20.2 0.0 0.00021 19.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) YopD PF05844.12 KXX74473.1 - 0.065 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 YopD protein Pex2_Pex12 PF04757.14 KXX74474.1 - 2.1e-38 132.2 0.2 3.2e-38 131.6 0.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KXX74474.1 - 0.0013 18.8 4.2 0.0025 17.9 4.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXX74474.1 - 0.033 14.2 0.9 0.087 12.9 0.9 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXX74474.1 - 7.4 6.5 9.4 7.9 6.4 5.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NAD_binding_6 PF08030.12 KXX74475.1 - 1.6e-24 86.8 0.0 2.7e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXX74475.1 - 4.2e-23 81.5 0.0 9e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXX74475.1 - 1.6e-20 73.5 16.6 2e-20 73.2 10.6 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KXX74475.1 - 0.037 14.7 0.0 2.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain LrgA PF03788.14 KXX74475.1 - 0.14 12.1 1.4 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 LrgA family FAD_binding_6 PF00970.24 KXX74475.1 - 0.15 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain 3HCDH_N PF02737.18 KXX74476.1 - 2.7e-22 79.5 0.0 5.8e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXX74476.1 - 0.047 13.3 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KXX74476.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hemerythrin PF01814.23 KXX74477.1 - 6.2e-11 43.0 0.3 8.2e-11 42.6 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Lactamase_B PF00753.27 KXX74478.1 - 1.2e-06 28.7 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_transf_90 PF05686.12 KXX74479.1 - 2e-09 36.9 0.3 0.0074 15.2 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 DHHC PF01529.20 KXX74480.1 - 5.3e-33 114.0 0.2 5.3e-33 114.0 0.2 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Myosin_head PF00063.21 KXX74481.1 - 1.1e-238 793.9 4.2 1.3e-238 793.7 4.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KXX74481.1 - 2.6e-48 164.2 0.0 4.6e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KXX74481.1 - 4.4e-12 45.4 0.2 8.3e-12 44.5 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX74481.1 - 2.9e-09 36.6 0.0 6.8e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX74481.1 - 1.7e-07 30.8 0.0 3.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KXX74481.1 - 0.0032 17.1 10.7 0.16 11.8 2.3 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 KXX74481.1 - 0.01 15.4 0.2 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KXX74481.1 - 0.036 14.3 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX74481.1 - 0.1 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KXX74481.1 - 0.13 12.2 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain SepF PF04472.12 KXX74481.1 - 0.14 12.4 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Cell division protein SepF DUF4913 PF16259.5 KXX74481.1 - 0.24 11.5 1.5 0.66 10.1 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Cytochrom_B558a PF05038.13 KXX74482.1 - 0.003 17.1 0.5 0.0079 15.8 0.4 1.8 1 1 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit COesterase PF00135.28 KXX74483.1 - 3.3e-66 224.2 0.0 7.6e-66 223.0 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX74483.1 - 8.2e-07 29.1 0.1 5.1e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX74483.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Gly_kinase PF02595.15 KXX74486.1 - 1.4e-125 419.1 0.6 1.6e-125 418.9 0.6 1.0 1 0 0 1 1 1 1 Glycerate kinase family PucR PF07905.11 KXX74486.1 - 0.064 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family DUF5558 PF17713.1 KXX74486.1 - 2.2 8.6 5.2 0.49 10.8 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5558) MFS_1 PF07690.16 KXX74487.1 - 3.9e-42 144.4 17.9 3.9e-42 144.4 17.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74487.1 - 3e-13 49.5 0.3 3e-13 49.5 0.3 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXX74487.1 - 2.8e-07 29.2 2.6 2.8e-07 29.2 2.6 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KXX74487.1 - 0.00068 18.2 0.8 0.00099 17.6 0.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HET PF06985.11 KXX74488.1 - 8.9e-29 100.7 0.0 1.7e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cyanate_lyase PF02560.14 KXX74488.1 - 0.074 12.9 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Cyanate lyase C-terminal domain Glyco_hydro_61 PF03443.14 KXX74489.1 - 1.8e-59 201.2 0.1 2.1e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CAS_CSE1 PF03378.15 KXX74491.1 - 1.5e-184 613.7 0.0 2.6e-184 612.8 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KXX74491.1 - 4.3e-153 509.5 2.9 2.3e-152 507.1 3.7 1.8 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 KXX74491.1 - 1.1e-13 50.8 0.0 3.4e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXX74491.1 - 0.023 14.8 0.3 1.7 8.7 0.0 3.3 2 1 0 2 2 2 0 Exportin 1-like protein V-ATPase_H_N PF03224.14 KXX74491.1 - 0.12 11.6 1.0 0.47 9.7 0.3 2.3 1 1 2 3 3 3 0 V-ATPase subunit H ACDC PF14733.6 KXX74491.1 - 0.14 12.5 0.1 1.4 9.3 0.0 2.8 2 1 0 2 2 2 0 AP2-coincident C-terminal DUF3384 PF11864.8 KXX74492.1 - 9.4e-145 483.2 2.0 1.9e-144 482.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KXX74492.1 - 1.6e-52 177.8 0.0 4e-52 176.5 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KXX74492.1 - 1.4e-40 139.5 1.2 8.6e-36 123.8 0.0 3.6 4 0 0 4 4 4 3 Tuberin WD40 PF00400.32 KXX74493.1 - 9.5e-17 61.1 13.5 0.00017 22.3 0.0 6.8 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74493.1 - 1.4e-14 54.1 0.2 0.0014 18.9 0.0 5.7 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXX74493.1 - 6.1e-07 29.5 0.1 2.2e-05 24.4 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KXX74493.1 - 0.0001 22.2 0.0 0.19 11.7 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KXX74493.1 - 0.014 15.1 0.0 6.2 6.6 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature CLTH PF10607.9 KXX74493.1 - 0.051 13.5 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain ParBc_2 PF08857.11 KXX74493.1 - 0.11 12.6 0.1 0.48 10.5 0.1 1.9 2 0 0 2 2 2 0 Putative ParB-like nuclease WD40_like PF17005.5 KXX74493.1 - 0.23 10.8 0.0 7.1 5.9 0.0 2.6 2 1 0 3 3 3 0 WD40-like domain Dynamin_M PF01031.20 KXX74494.1 - 9.4e-103 343.3 0.0 1.8e-102 342.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXX74494.1 - 2.6e-57 193.5 0.0 5e-57 192.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXX74494.1 - 9.6e-30 102.6 4.8 9.6e-30 102.6 4.8 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXX74494.1 - 7.3e-06 26.0 0.3 7.5e-05 22.8 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KXX74494.1 - 0.021 14.5 2.0 2.3 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain PNISR PF15996.5 KXX74495.1 - 0.38 11.0 3.7 0.86 9.8 3.7 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Pkinase PF00069.25 KXX74496.1 - 1.3e-51 175.5 0.0 3.7e-37 128.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74496.1 - 3.3e-23 82.3 0.0 2.4e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXX74496.1 - 5.8e-05 22.5 0.6 0.0059 15.9 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXX74496.1 - 9.6e-05 21.5 0.0 0.00032 19.8 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 KXX74496.1 - 0.00012 22.7 1.4 0.00027 21.6 1.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KXX74496.1 - 0.0016 18.4 1.0 0.22 11.4 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXX74496.1 - 0.012 15.0 0.1 0.029 13.7 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actino_peptide PF14408.6 KXX74496.1 - 0.041 14.0 4.6 0.087 12.9 4.6 1.4 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes Choline_kinase PF01633.20 KXX74496.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 KXX74496.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase G_glu_transpept PF01019.21 KXX74497.1 - 4.7e-131 438.1 0.0 7e-131 437.5 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CoA_transf_3 PF02515.17 KXX74498.1 - 3.9e-66 223.7 0.0 5.6e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III DUF2484 PF10658.9 KXX74498.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) Glutaredoxin PF00462.24 KXX74499.1 - 1.2e-15 57.4 0.0 2.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin OPT PF03169.15 KXX74500.1 - 5.8e-134 448.0 46.7 6.7e-134 447.8 46.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein p450 PF00067.22 KXX74501.1 - 2.2e-51 175.1 0.0 2.9e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.20 KXX74502.1 - 6.8e-37 126.7 25.7 6.5e-32 110.5 1.4 3.7 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXX74502.1 - 3.8e-29 101.7 0.9 3.8e-29 101.7 0.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KXX74502.1 - 2.6e-17 62.2 0.0 7.2e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KXX74502.1 - 3.8e-14 53.5 0.0 1.2e-13 51.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXX74502.1 - 4e-13 49.3 0.0 8.5e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXX74502.1 - 1.1e-05 25.3 2.6 2.6e-05 24.1 1.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IncE PF17627.2 KXX74502.1 - 0.045 13.8 1.9 0.12 12.4 1.1 2.2 1 1 0 1 1 1 0 Inclusion membrane protein E DUF2463 PF09591.10 KXX74502.1 - 0.11 12.4 2.9 0.28 11.0 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) ABC_tran PF00005.27 KXX74503.1 - 4e-06 27.4 0.1 6.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXX74503.1 - 0.016 14.7 0.3 0.019 14.4 0.3 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RTA1 PF04479.13 KXX74504.1 - 1.2e-49 168.7 8.9 2e-49 168.0 8.9 1.3 1 0 0 1 1 1 1 RTA1 like protein RRP14 PF15459.6 KXX74504.1 - 0.21 12.2 5.9 0.38 11.4 5.9 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Cyto_heme_lyase PF01265.17 KXX74505.1 - 1.6e-42 146.1 10.0 2.3e-41 142.3 10.0 2.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase S36_mt PF10937.8 KXX74506.1 - 7.6e-41 140.3 0.8 9.1e-41 140.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF4695 PF15766.5 KXX74506.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) MDD_C PF18376.1 KXX74507.1 - 2.5e-64 216.5 0.0 3.4e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KXX74507.1 - 1.9e-08 34.4 1.9 1.9e-08 34.4 1.9 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF647 PF04884.14 KXX74508.1 - 7.5e-99 330.2 1.1 9.9e-99 329.8 1.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TauE PF01925.19 KXX74508.1 - 0.059 13.0 2.0 0.12 12.0 2.0 1.5 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE UbiA PF01040.18 KXX74509.1 - 8.5e-23 80.9 5.2 8.5e-23 80.9 5.2 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family p450 PF00067.22 KXX74510.1 - 4.8e-39 134.4 0.0 5.9e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_8 PF08022.12 KXX74511.1 - 2.5e-08 34.0 0.0 4.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXX74511.1 - 0.00011 22.4 0.6 0.00011 22.4 0.6 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXX74511.1 - 0.00077 19.6 0.0 0.012 15.8 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 KXX74511.1 - 0.04 14.5 0.1 0.04 14.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF3392 PF11872.8 KXX74511.1 - 0.059 13.6 1.0 7 7.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Acyl-CoA_dh_N PF02771.16 KXX74512.1 - 8.9e-25 87.6 0.1 1.9e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXX74512.1 - 6e-24 85.0 0.3 1.1e-23 84.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXX74512.1 - 1.4e-18 66.9 0.0 2.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXX74512.1 - 1.7e-06 28.3 0.3 3.2e-06 27.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TPR_10 PF13374.6 KXX74513.1 - 8.2e-89 289.4 10.9 5.9e-13 48.2 0.0 8.5 7 1 1 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KXX74513.1 - 8.5e-69 227.8 13.9 2.9e-15 56.3 0.0 7.1 1 1 5 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KXX74513.1 - 1.1e-26 90.8 5.6 0.0032 17.4 0.0 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXX74513.1 - 1.3e-18 65.6 6.5 0.65 10.3 0.0 8.5 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXX74513.1 - 8.3e-17 61.6 5.8 0.0016 19.0 0.0 8.3 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 KXX74513.1 - 3.2e-16 58.2 6.2 0.34 11.7 0.0 8.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX74513.1 - 1.1e-15 56.6 0.7 0.72 9.8 0.0 7.9 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXX74513.1 - 1.1e-14 54.7 0.2 0.038 14.5 0.0 7.0 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX74513.1 - 2.7e-14 53.3 13.5 2.2e-09 37.1 3.3 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_17 PF13431.6 KXX74513.1 - 5e-13 48.5 2.7 0.71 10.4 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_5 PF12688.7 KXX74513.1 - 1.2e-09 38.5 0.9 0.089 13.0 0.0 5.2 1 1 4 5 5 5 2 Tetratrico peptide repeat NB-ARC PF00931.22 KXX74513.1 - 4.8e-09 35.8 0.0 1.9e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain TPR_14 PF13428.6 KXX74513.1 - 2.7e-08 34.0 11.3 8.5 7.5 0.0 8.9 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX74513.1 - 5.1e-07 29.4 4.3 12 6.4 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.20 KXX74513.1 - 6.8e-05 22.9 3.4 39 4.8 0.0 6.6 7 0 0 7 7 6 0 PPR repeat NACHT PF05729.12 KXX74513.1 - 0.00094 19.1 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 KXX74513.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ses_B PF17046.5 KXX74513.1 - 0.01 15.8 0.4 0.019 14.9 0.4 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein DUF1897 PF09005.10 KXX74513.1 - 0.023 14.2 7.4 11 5.6 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) AAA_16 PF13191.6 KXX74513.1 - 0.023 15.1 0.1 0.13 12.6 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain Ntox35 PF15534.6 KXX74513.1 - 0.05 14.0 2.4 28 5.2 0.0 4.4 4 1 0 5 5 5 0 Bacterial toxin 35 RPN6_N PF18055.1 KXX74513.1 - 0.071 13.5 2.0 2.5 8.5 0.2 3.3 1 1 3 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain SnoaL_4 PF13577.6 KXX74513.1 - 0.099 12.8 2.8 4.3 7.5 0.1 3.3 2 1 1 3 3 3 0 SnoaL-like domain TPR_6 PF13174.6 KXX74513.1 - 1.6 9.5 14.0 99 3.9 0.1 7.1 7 1 0 7 7 6 0 Tetratricopeptide repeat UQ_con PF00179.26 KXX74514.1 - 3e-53 179.2 0.0 3.3e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXX74514.1 - 0.0089 16.3 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXX74514.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 KXX74514.1 - 0.024 14.3 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Helo_like_N PF17111.5 KXX74516.1 - 1.5e-16 60.4 0.4 1.8e-16 60.2 0.4 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins FAA_hydro_N_2 PF18288.1 KXX74516.1 - 0.12 12.8 0.5 17 5.9 0.1 2.7 1 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 NAD_binding_6 PF08030.12 KXX74517.1 - 5.7e-31 107.8 0.0 1.1e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXX74517.1 - 6.7e-20 71.2 0.8 1.3e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KXX74517.1 - 7.5e-19 68.1 20.1 3.1e-18 66.1 12.1 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component XPG_I PF00867.18 KXX74518.1 - 2.1e-31 108.1 1.8 4.2e-31 107.1 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KXX74518.1 - 5e-25 87.9 0.0 5e-25 87.9 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KXX74518.1 - 2.9e-05 24.6 0.4 0.00025 21.6 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KXX74518.1 - 0.064 13.9 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain TACC_C PF05010.14 KXX74519.1 - 0.14 11.9 27.8 0.07 12.9 6.1 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal p450 PF00067.22 KXX74519.1 - 0.18 10.5 8.2 0.19 10.4 1.1 2.2 1 1 0 2 2 2 0 Cytochrome P450 DUF724 PF05266.14 KXX74519.1 - 0.2 11.4 23.1 0.036 13.9 2.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Ribonuc_red_lgN PF00317.21 KXX74519.1 - 0.24 11.4 1.3 6.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain TMF_DNA_bd PF12329.8 KXX74519.1 - 0.37 10.8 22.7 0.64 10.0 0.1 4.4 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding Nas2_N PF18265.1 KXX74519.1 - 2 8.4 13.3 3.8 7.5 2.4 3.8 3 0 0 3 3 3 0 Nas2 N_terminal domain Filament PF00038.21 KXX74519.1 - 2.6 7.5 31.1 14 5.1 10.0 2.4 1 1 1 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 KXX74519.1 - 2.8 7.2 20.5 0.17 11.2 9.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5446 PF17522.2 KXX74519.1 - 5.4 7.3 14.7 8.3 6.7 5.3 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5446) Cas6b_C PF17262.2 KXX74519.1 - 7.5 6.7 6.1 1.2 9.2 0.6 2.3 3 0 0 3 3 3 0 Cas6b C-terminal domain DnaJ PF00226.31 KXX74521.1 - 3e-10 40.1 0.1 0.00069 19.7 0.0 3.9 5 0 0 5 5 5 2 DnaJ domain Pheromone PF08015.11 KXX74521.1 - 2.6 9.2 6.1 2.2 9.4 0.0 3.7 3 1 0 3 3 3 0 Fungal mating-type pheromone Methyltransf_23 PF13489.6 KXX74522.1 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX74522.1 - 0.00073 20.2 0.0 0.0014 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Mt_ATP-synt_D PF05873.12 KXX74524.1 - 4.2e-23 81.9 2.2 5.1e-23 81.6 2.2 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) APG6_N PF17675.1 KXX74524.1 - 0.47 11.0 6.0 1.2 9.7 6.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region NAC PF01849.18 KXX74525.1 - 2.3e-23 81.9 0.5 7.7e-23 80.2 0.1 2.0 2 0 0 2 2 2 1 NAC domain CCDC106 PF15794.5 KXX74525.1 - 0.083 12.6 6.1 0.46 10.2 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Myc_N PF01056.18 KXX74525.1 - 0.35 10.7 8.9 0.49 10.2 8.8 1.3 1 1 0 1 1 1 0 Myc amino-terminal region PGA2 PF07543.12 KXX74525.1 - 0.43 10.6 12.2 3.1 7.8 0.6 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_L14e PF01929.17 KXX74526.1 - 1.8e-32 111.7 0.8 2.5e-32 111.2 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 Acetyltransf_9 PF13527.7 KXX74527.1 - 1.2e-05 25.4 0.1 2.8e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX74527.1 - 0.0026 17.7 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX74527.1 - 0.0031 17.9 0.0 0.0076 16.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX74527.1 - 0.0035 17.6 0.3 0.01 16.0 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 KXX74527.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PFK PF00365.20 KXX74528.1 - 8.4e-188 622.5 0.3 1e-105 353.1 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KXX74528.1 - 0.15 11.7 0.1 0.74 9.4 0.1 2.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain SKG6 PF08693.10 KXX74529.1 - 2.7e-05 23.5 2.0 5.1e-05 22.6 2.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 KXX74529.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Lipoprotein_1 PF00820.19 KXX74529.1 - 0.036 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein Podoplanin PF05808.11 KXX74529.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Podoplanin Romo1 PF10247.9 KXX74529.1 - 0.17 12.3 1.4 0.38 11.1 1.4 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 SNF2_N PF00176.23 KXX74531.1 - 2e-54 184.7 0.2 3.9e-54 183.7 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX74531.1 - 1e-17 64.5 0.0 2.4e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXX74531.1 - 2.3e-08 33.7 1.6 2.3e-08 33.7 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX74531.1 - 4.3e-08 33.1 1.3 7.8e-08 32.2 0.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXX74531.1 - 8.8e-08 31.9 2.5 1.9e-07 30.8 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX74531.1 - 1.9e-07 31.3 3.8 4.1e-07 30.2 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX74531.1 - 4.5e-07 29.6 4.5 8.9e-07 28.7 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXX74531.1 - 4.6e-07 30.0 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KXX74531.1 - 1.4e-06 28.1 3.3 2.8e-06 27.2 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXX74531.1 - 0.00012 22.2 5.4 0.00027 21.0 5.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING PgaD PF13994.6 KXX74531.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 PgaD-like protein Flavoprotein PF02441.19 KXX74531.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Flavoprotein Prok-RING_4 PF14447.6 KXX74531.1 - 0.026 14.4 6.4 0.12 12.3 6.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXX74531.1 - 0.065 13.0 0.6 0.17 11.7 0.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KXX74531.1 - 0.071 12.9 3.9 0.29 11.0 4.1 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.20 KXX74531.1 - 0.098 12.4 1.6 0.26 11.0 1.6 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Baculo_IE-1 PF05290.11 KXX74531.1 - 0.12 12.3 0.9 0.31 11.0 0.9 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Cwf_Cwc_15 PF04889.12 KXX74531.1 - 0.34 10.6 30.1 0.031 14.0 10.7 3.2 4 0 0 4 4 3 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_Rpc4 PF05132.14 KXX74531.1 - 1.4 9.3 4.5 5.3 7.5 4.5 2.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 DZR PF12773.7 KXX74531.1 - 2.1 8.4 7.0 1 9.4 3.9 2.0 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_6 PF14835.6 KXX74531.1 - 7.5 6.5 5.9 46 4.0 5.9 2.2 1 1 0 1 1 1 0 zf-RING of BARD1-type protein CDC45 PF02724.14 KXX74531.1 - 10 4.3 14.5 1.3 7.2 10.1 1.7 2 0 0 2 2 2 0 CDC45-like protein Phosphodiest PF01663.22 KXX74532.1 - 8.8e-97 324.9 1.2 1.2e-96 324.4 1.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXX74532.1 - 0.00098 18.6 0.3 0.072 12.5 0.3 2.3 1 1 0 1 1 1 1 Sulfatase DUF948 PF06103.11 KXX74532.1 - 0.043 14.1 0.1 3.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Apo-CIII PF05778.12 KXX74532.1 - 0.15 11.7 1.9 0.33 10.6 1.9 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Isochorismatase PF00857.20 KXX74533.1 - 1.6e-10 41.4 0.0 2.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family ATP-cone PF03477.16 KXX74533.1 - 0.17 12.5 0.0 0.39 11.3 0.0 1.5 1 1 0 1 1 1 0 ATP cone domain zf-C2H2 PF00096.26 KXX74534.1 - 0.0023 18.3 4.8 0.16 12.5 0.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX74534.1 - 0.31 12.0 7.7 3.6 8.7 0.9 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger Kinetochor_Ybp2 PF08568.10 KXX74535.1 - 4.6e-119 398.7 0.0 6.5e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DUF1840 PF08895.11 KXX74535.1 - 0.49 10.7 2.0 0.95 9.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) SET PF00856.28 KXX74536.1 - 7.4e-14 52.5 0.1 3.4e-13 50.3 0.1 2.0 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KXX74536.1 - 0.031 14.9 0.1 0.9 10.2 0.0 2.5 2 0 0 2 2 2 0 SAF domain 2OG-FeII_Oxy_3 PF13640.6 KXX74537.1 - 0.0016 19.3 0.0 0.0055 17.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_28 PF03033.20 KXX74538.1 - 1.1e-14 54.6 0.0 9.8e-14 51.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXX74538.1 - 1.4e-06 27.4 0.0 2.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KXX74538.1 - 0.0048 17.2 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KXX74538.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Utp13 PF08625.11 KXX74538.1 - 0.16 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain UPF0767 PF15990.5 KXX74538.1 - 0.64 10.2 3.2 0.39 10.9 0.1 2.3 2 0 0 2 2 2 0 UPF0767 family Adeno_E3_CR2 PF02439.15 KXX74539.1 - 5.4 6.9 8.6 0.2 11.5 2.1 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Zn_clus PF00172.18 KXX74540.1 - 1.3e-05 25.2 7.7 2.3e-05 24.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TTRAP PF14203.6 KXX74540.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein DSPc PF00782.20 KXX74542.1 - 3.5e-10 39.8 0.0 7.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXX74542.1 - 0.0037 17.5 0.0 0.0075 16.6 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain TMEM154 PF15102.6 KXX74542.1 - 0.15 11.9 6.3 0.035 14.0 2.8 1.6 2 0 0 2 2 2 0 TMEM154 protein family THOC2_N PF16134.5 KXX74543.1 - 1.8e-226 753.7 0.0 5e-226 752.2 0.0 1.7 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KXX74543.1 - 1.3e-97 326.6 0.4 1.9e-97 326.1 0.4 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KXX74543.1 - 3.2e-27 94.4 0.1 6.9e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Ribosomal_S17e PF00833.18 KXX74544.1 - 2.6e-59 198.5 0.1 3e-59 198.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 KXX74545.1 - 1.1e-126 423.4 0.0 1.3e-126 423.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit TTSSLRR PF12468.8 KXX74545.1 - 0.067 13.4 0.7 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Abhydrolase_1 PF00561.20 KXX74546.1 - 3.1e-48 164.7 0.0 5e-48 164.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX74546.1 - 0.0045 17.6 7.0 0.014 16.0 7.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family WSC PF01822.19 KXX74547.1 - 2.8e-11 43.5 3.8 5.1e-11 42.6 3.8 1.4 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.11 KXX74547.1 - 0.0011 19.0 0.5 0.0018 18.4 0.5 1.3 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 KXX74547.1 - 0.002 18.7 0.3 0.002 18.7 0.3 2.1 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Adeno_E3_CR2 PF02439.15 KXX74547.1 - 0.003 17.3 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Gram_pos_anchor PF00746.21 KXX74547.1 - 0.0075 16.2 0.4 0.019 14.9 0.4 1.7 1 0 0 1 1 1 1 LPXTG cell wall anchor motif Yip1 PF04893.17 KXX74547.1 - 0.048 13.4 0.2 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Yip1 domain VSP PF03302.13 KXX74547.1 - 0.073 11.9 0.2 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF5518 PF17647.1 KXX74547.1 - 1.1 9.5 10.3 2.9 8.1 10.3 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5518) Hist_deacetyl PF00850.19 KXX74548.1 - 3.1e-51 174.7 0.1 4.9e-51 174.0 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Spo7 PF03907.13 KXX74550.1 - 2.4e-94 315.0 0.1 3.5e-94 314.4 0.1 1.3 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 KXX74551.1 - 4.7e-21 75.6 0.0 8.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX74551.1 - 1.9e-15 58.1 2.3 4.2e-14 53.7 0.6 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX74551.1 - 4.3e-15 55.6 0.0 1.5e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KXX74551.1 - 1.7e-05 24.3 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KXX74551.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KXX74551.1 - 0.0093 16.1 0.0 0.028 14.6 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 KXX74551.1 - 0.049 13.4 0.0 0.91 9.3 0.0 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KXX74551.1 - 0.095 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KXX74551.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 KXX74551.1 - 0.17 10.8 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme TGT PF01702.18 KXX74553.1 - 3.7e-139 463.8 0.0 4.3e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase XTBD PF11952.8 KXX74553.1 - 0.045 13.5 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD Dabb PF07876.12 KXX74554.1 - 0.13 12.9 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Methyltransf_2 PF00891.18 KXX74556.1 - 8.1e-23 80.8 0.0 1.4e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXX74556.1 - 0.021 15.5 0.0 0.064 14.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KXX74556.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HATPase_c PF02518.26 KXX74557.1 - 7.1e-22 78.0 0.0 1.5e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 KXX74557.1 - 1.3e-10 41.5 0.5 0.13 12.6 0.0 5.7 5 1 1 6 6 6 3 PAS fold PAS_9 PF13426.7 KXX74557.1 - 4.2e-10 39.8 0.0 0.016 15.5 0.0 4.0 3 1 0 3 3 3 2 PAS domain HisKA PF00512.25 KXX74557.1 - 1.9e-09 37.4 0.0 1.3e-08 34.7 0.0 2.5 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 KXX74557.1 - 8.7e-07 28.8 0.0 0.0044 17.0 0.0 3.7 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KXX74557.1 - 8.9e-07 28.9 0.0 0.0063 16.5 0.0 4.0 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.12 KXX74557.1 - 1.7e-05 25.0 0.0 0.44 10.9 0.0 3.4 2 1 0 2 2 2 2 PAS fold Response_reg PF00072.24 KXX74557.1 - 0.042 14.0 0.6 0.21 11.8 0.0 2.5 2 0 0 2 2 2 0 Response regulator receiver domain Response_reg PF00072.24 KXX74558.1 - 4.2e-09 36.6 0.0 5.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain G-patch PF01585.23 KXX74559.1 - 1.3e-11 44.2 1.9 2.9e-11 43.1 1.9 1.7 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KXX74559.1 - 1.8e-09 36.8 0.4 4.8e-09 35.4 0.4 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KXX74559.1 - 2.4e-08 33.7 0.1 0.00041 20.1 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KXX74559.1 - 0.0008 19.5 5.4 0.0028 17.7 3.5 2.6 2 0 0 2 2 2 1 G-patch domain RED_N PF07808.13 KXX74559.1 - 0.023 14.3 1.1 0.051 13.2 1.1 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF35_N PF12172.8 KXX74559.1 - 0.052 13.4 2.3 0.12 12.3 2.3 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 KXX74559.1 - 2.8 8.1 4.9 1.2 9.2 1.7 2.1 3 0 0 3 3 3 0 Double zinc ribbon Asp PF00026.23 KXX74561.1 - 1.1e-60 205.7 0.0 1.9e-60 204.9 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX74561.1 - 5.8e-13 49.5 4.7 8.6e-12 45.7 2.1 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXX74561.1 - 1.2e-06 29.0 0.8 0.078 13.6 0.5 3.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KXX74561.1 - 7.9e-05 23.1 0.8 1.7 9.3 0.0 3.9 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Hydrolase_6 PF13344.6 KXX74562.1 - 5.5e-18 65.0 0.0 1.4e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXX74562.1 - 2e-16 59.8 0.1 5.6e-16 58.4 0.1 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXX74562.1 - 2.6e-05 24.6 0.0 1.2 9.4 0.0 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXX74562.1 - 0.021 14.9 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Med8 PF10232.9 KXX74563.1 - 0.17 11.5 6.3 0.063 12.9 3.1 1.8 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 MoaE PF02391.17 KXX74564.1 - 2.7e-39 134.0 0.1 3.3e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 MoaE protein OPT PF03169.15 KXX74565.1 - 1.5e-188 628.3 57.3 1.7e-188 628.2 57.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PALP PF00291.25 KXX74566.1 - 3.4e-80 269.6 0.5 4.2e-80 269.3 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXX74566.1 - 7.1e-38 128.3 0.0 1.2e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 KXX74567.1 - 3.9e-21 75.0 0.5 7.2e-21 74.2 0.5 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3824 PF12868.7 KXX74567.1 - 0.59 10.8 16.7 1.4 9.6 3.2 2.4 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF4407 PF14362.6 KXX74567.1 - 0.89 8.8 9.7 1.1 8.5 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KXX74567.1 - 1.4 6.8 5.1 1.6 6.6 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 KXX74567.1 - 9.8 4.8 7.8 12 4.5 7.8 1.2 1 0 0 1 1 1 0 Presenilin TLD PF07534.16 KXX74568.1 - 2.7e-28 99.0 0.0 8.5e-28 97.3 0.0 1.8 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 KXX74568.1 - 4.6e-16 59.6 2.1 5.1e-16 59.5 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function RPEL PF02755.15 KXX74569.1 - 4.9e-20 70.6 4.5 2.8e-10 39.5 0.2 2.5 3 0 0 3 3 3 2 RPEL repeat FKBP_C PF00254.28 KXX74570.1 - 2.1e-31 108.1 0.0 3e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Tannase PF07519.11 KXX74571.1 - 2.7e-20 72.7 0.0 2.9e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase IMS PF00817.20 KXX74572.1 - 1.3e-42 145.4 0.0 2.8e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXX74572.1 - 4.4e-13 49.9 0.2 1.3e-12 48.4 0.2 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXX74572.1 - 8.5e-06 25.8 0.0 2.7e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Memo PF01875.17 KXX74573.1 - 2.1e-30 105.8 0.0 2.9e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Tannase PF07519.11 KXX74574.1 - 4.2e-64 217.2 0.3 5.9e-64 216.7 0.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase NAD_binding_4 PF07993.12 KXX74575.1 - 7.4e-34 117.1 0.0 1.3e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXX74575.1 - 9.3e-25 87.1 0.0 1.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXX74575.1 - 1.3e-11 44.5 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXX74575.1 - 3.7e-08 33.6 0.0 2.8e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 KXX74575.1 - 0.016 15.1 0.0 0.18 11.7 0.0 2.4 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KXX74575.1 - 0.041 14.3 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXX74575.1 - 0.17 12.0 0.4 6 7.0 0.0 2.6 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus PS-DH PF14765.6 KXX74576.1 - 2e-61 207.8 0.1 3.2e-61 207.2 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXX74576.1 - 2.9e-58 196.7 0.0 5e-58 196.0 0.0 1.4 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 KXX74576.1 - 3e-58 197.4 0.0 5.9e-58 196.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXX74576.1 - 3.2e-54 184.6 0.0 6.3e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX74576.1 - 7.9e-39 132.3 0.0 1.6e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXX74576.1 - 9.1e-23 80.9 0.1 1.9e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KXX74576.1 - 1.8e-20 73.5 0.0 7.4e-20 71.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74576.1 - 8.9e-12 45.6 0.0 3e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX74576.1 - 1.1e-10 41.6 0.0 2.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74576.1 - 5.9e-10 39.1 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74576.1 - 1.6e-08 35.0 0.0 6.2e-08 33.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXX74576.1 - 3.7e-08 33.6 0.0 9.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 KXX74576.1 - 5.1e-07 29.7 0.0 2.9e-06 27.3 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase SAT PF16073.5 KXX74576.1 - 3.5e-06 26.9 0.9 9.2e-05 22.3 0.9 2.5 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short PF00106.25 KXX74576.1 - 0.0002 20.9 0.0 0.00049 19.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_16 PF10294.9 KXX74576.1 - 0.0016 18.2 0.0 0.006 16.3 0.0 1.8 1 1 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KXX74576.1 - 0.0052 16.2 0.0 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_zinc_N_2 PF13602.6 KXX74576.1 - 0.0092 17.0 0.0 0.087 13.9 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF938 PF06080.12 KXX74576.1 - 0.023 14.5 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Lipase_GDSL_2 PF13472.6 KXX74577.1 - 4.6e-15 56.5 0.2 6.2e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX74577.1 - 9.4e-07 29.0 0.0 3.2e-05 24.0 0.0 2.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase tRNA-synt_2c PF01411.19 KXX74577.1 - 0.034 12.7 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) AMP-binding PF00501.28 KXX74579.1 - 2.9e-101 339.1 0.0 4.8e-101 338.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KXX74579.1 - 1.4e-83 280.4 0.2 5.4e-83 278.4 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX74579.1 - 3.5e-58 196.5 2.3 3.1e-57 193.4 1.3 2.8 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KXX74579.1 - 5.9e-55 187.0 0.0 1.1e-54 186.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KXX74579.1 - 1.5e-51 175.0 0.0 7.2e-51 172.8 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KXX74579.1 - 4.2e-44 149.3 1.1 1.1e-43 148.0 1.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KXX74579.1 - 2e-22 79.3 0.0 4.3e-11 43.0 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXX74579.1 - 3.8e-13 49.9 0.0 1.1e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KXX74579.1 - 1.2e-08 34.8 0.2 9.3e-07 28.5 0.0 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KXX74579.1 - 8.1e-07 29.9 0.0 2.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 KXX74579.1 - 4.8e-06 26.1 0.1 1.2e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KXX74579.1 - 8.1e-06 25.5 0.0 0.031 13.7 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXX74579.1 - 2.1e-05 24.1 0.0 9.3e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase LRAT PF04970.13 KXX74579.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase NmrA PF05368.13 KXX74579.1 - 0.12 11.9 0.2 7.5 6.0 0.0 2.5 2 0 0 2 2 2 0 NmrA-like family NmrA PF05368.13 KXX74580.1 - 5.1e-13 49.1 0.0 7.1e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KXX74580.1 - 5.6e-05 23.1 0.0 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXX74580.1 - 0.0014 18.2 0.0 0.067 12.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX74580.1 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXX74580.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PhyH PF05721.13 KXX74582.1 - 1.6e-36 126.6 0.0 2e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXX74582.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) DJ-1_PfpI PF01965.24 KXX74583.1 - 6.3e-16 58.6 0.0 4.9e-15 55.7 0.0 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXX74583.1 - 7.7e-08 32.3 0.0 9.4e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like DZR PF12773.7 KXX74584.1 - 0.0013 18.7 0.9 0.0026 17.8 0.9 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KXX74584.1 - 0.0057 16.3 3.7 0.54 10.0 0.3 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 KXX74584.1 - 0.015 14.9 7.4 0.7 9.6 1.4 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 KXX74584.1 - 0.039 13.4 5.8 0.095 12.1 5.8 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KXX74584.1 - 0.37 10.7 5.5 5.1 7.1 0.6 2.4 2 0 0 2 2 2 0 Nudix N-terminal Acyl_transf_3 PF01757.22 KXX74585.1 - 1.6e-30 106.4 35.1 1.9e-30 106.1 35.1 1.1 1 0 0 1 1 1 1 Acyltransferase family zf-CCHC PF00098.23 KXX74586.1 - 3.8e-06 26.7 5.1 0.001 19.1 1.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KXX74586.1 - 0.14 12.0 6.0 2.2 8.2 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle NAPRTase PF04095.16 KXX74586.1 - 0.16 11.6 1.9 0.17 11.5 0.4 1.8 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) family AAR2 PF05282.11 KXX74586.1 - 0.34 10.3 3.6 0.63 9.4 3.6 1.5 1 0 0 1 1 1 0 AAR2 protein YqaJ PF09588.10 KXX74586.1 - 0.61 10.2 3.3 1.3 9.2 1.8 2.1 2 0 0 2 2 2 0 YqaJ-like viral recombinase domain Gly_transf_sug PF04488.15 KXX74588.1 - 8.2e-11 42.4 2.0 9.9e-11 42.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Acetyltransf_6 PF13480.7 KXX74588.1 - 0.032 14.4 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2052 PF09747.9 KXX74588.1 - 0.26 11.4 22.4 0.4 10.8 22.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpc4 PF05132.14 KXX74588.1 - 0.56 10.6 15.4 1 9.8 15.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 KXX74588.1 - 2.9 6.7 26.0 4.3 6.1 26.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.16 KXX74588.1 - 6.1 6.8 9.1 9.4 6.2 9.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 KXX74588.1 - 6.2 6.6 29.2 9.3 6.0 29.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 KXX74588.1 - 6.5 5.8 20.3 9.2 5.3 20.3 1.2 1 0 0 1 1 1 0 SprA-related family Ion_trans PF00520.31 KXX74589.1 - 1.1e-10 41.2 21.5 1.3e-09 37.6 21.5 2.2 1 1 0 1 1 1 1 Ion transport protein PNTB_4TM PF12769.7 KXX74589.1 - 0.034 14.6 0.3 0.095 13.2 0.3 1.7 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch zf-C2H2_4 PF13894.6 KXX74590.1 - 0.0029 18.3 12.5 0.11 13.4 0.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf_UBZ PF18439.1 KXX74590.1 - 0.1 12.2 1.8 2.6 7.7 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 KXX74590.1 - 1.9 8.8 4.1 6.7 7.1 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon Zn_ribbon_SprT PF17283.2 KXX74590.1 - 3.3 7.7 6.1 0.32 10.9 1.1 1.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_2 PF13465.6 KXX74590.1 - 3.5 8.2 8.2 0.55 10.7 1.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain SKG6 PF08693.10 KXX74591.1 - 0.13 11.7 0.4 0.27 10.7 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cellulase PF00150.18 KXX74592.1 - 1.3e-24 87.1 1.7 3e-24 85.9 0.1 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL_2 PF13472.6 KXX74592.1 - 6.1e-21 75.6 0.8 9.6e-20 71.7 0.2 2.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX74592.1 - 7.7e-10 39.1 0.0 1.8e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_2_C PF02836.17 KXX74592.1 - 3.9e-05 22.9 0.0 8.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain OSK PF17182.4 KXX74592.1 - 0.00055 19.2 0.0 0.00087 18.6 0.0 1.2 1 0 0 1 1 1 1 OSK domain Glyco_hydro_42 PF02449.15 KXX74592.1 - 0.013 14.9 0.1 0.054 12.8 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase Fungal_trans PF04082.18 KXX74594.1 - 1.6e-31 109.3 0.0 2.4e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX74594.1 - 5e-07 29.7 10.5 8.8e-07 28.9 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.19 KXX74595.1 - 3e-73 242.0 65.7 1.8e-19 69.7 10.4 4.7 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.23 KXX74595.1 - 1e-23 84.3 0.1 2.3e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Peroxidase Lipase_3 PF01764.25 KXX74596.1 - 9e-32 109.9 0.0 1.3e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KXX74596.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXX74596.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PhrC_PhrF PF11131.8 KXX74596.1 - 0.33 10.6 2.9 0.27 10.9 0.3 2.2 2 0 0 2 2 2 0 Rap-phr extracellular signalling GAS2 PF02187.17 KXX74597.1 - 5.7e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain FXR_C1 PF16096.5 KXX74597.1 - 0.99 9.7 5.6 0.75 10.0 2.7 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 IBR PF01485.21 KXX74598.1 - 1.8e-21 76.1 37.6 2.1e-16 59.9 3.9 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KXX74598.1 - 2.3e-19 69.8 0.0 4.4e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KXX74598.1 - 0.00049 20.4 9.9 0.00049 20.4 9.9 3.8 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KXX74598.1 - 0.00092 19.2 7.3 0.00092 19.2 7.3 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXX74598.1 - 0.0012 18.6 6.6 0.0038 16.9 6.6 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXX74598.1 - 0.0059 16.5 9.8 0.0059 16.5 9.8 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX74598.1 - 0.007 16.3 9.9 0.007 16.3 9.9 3.8 3 1 1 4 4 4 1 zinc-RING finger domain RXT2_N PF08595.11 KXX74598.1 - 2 8.4 4.7 2.8 7.9 0.9 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal PAP2 PF01569.21 KXX74599.1 - 1.9e-14 53.6 6.7 8.4e-14 51.5 6.7 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KXX74599.1 - 0.041 14.0 1.9 0.91 9.7 0.0 2.8 2 1 1 3 3 3 0 Divergent PAP2 family Transmemb_17 PF09799.9 KXX74599.1 - 0.82 10.3 5.1 2.9 8.5 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein EphA2_TM PF14575.6 KXX74600.1 - 1.2 10.1 0.0 1.2 10.1 0.0 2.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain MARVEL PF01284.23 KXX74600.1 - 1.5 8.9 19.2 3.3 7.7 19.3 1.5 1 1 0 1 1 1 0 Membrane-associating domain SURF6 PF04935.12 KXX74601.1 - 3.9e-50 170.4 42.8 3.9e-50 170.4 42.8 4.3 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KXX74601.1 - 1.7e-17 63.8 1.5 1.7e-17 63.8 1.5 6.8 4 2 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 XPG_I PF00867.18 KXX74602.1 - 1.1e-22 80.2 0.0 2.6e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXX74602.1 - 1.8e-20 73.3 0.0 3.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KXX74602.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KXX74602.1 - 0.015 15.9 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Methyltransf_2 PF00891.18 KXX74603.1 - 3.9e-11 42.7 0.0 6.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain GPP34 PF05719.11 KXX74604.1 - 6.7e-69 232.0 0.1 8.4e-69 231.7 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) LCCL PF03815.19 KXX74605.1 - 7.4e-23 80.5 0.0 1.2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 LCCL domain Questin_oxidase PF14027.6 KXX74606.1 - 1.6e-40 139.7 0.0 1.9e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Pyridoxal_deC PF00282.19 KXX74607.1 - 6.3e-73 245.6 0.0 5.3e-72 242.6 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXX74607.1 - 0.0011 18.3 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXX74607.1 - 0.0037 16.3 0.0 0.0054 15.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V HNH PF01844.23 KXX74609.1 - 0.00068 19.8 1.3 0.0012 18.9 1.3 1.4 1 0 0 1 1 1 1 HNH endonuclease Thi4 PF01946.17 KXX74610.1 - 4e-112 373.1 0.0 4.9e-112 372.9 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXX74610.1 - 1.2e-08 34.9 0.8 1.4e-06 28.1 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX74610.1 - 4.6e-06 26.8 0.2 1.3e-05 25.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX74610.1 - 2.3e-05 23.7 0.8 0.0011 18.2 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXX74610.1 - 5.5e-05 22.4 0.3 9.9e-05 21.5 0.3 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX74610.1 - 7.3e-05 22.1 0.0 9.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX74610.1 - 0.00043 20.3 0.8 0.0016 18.4 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXX74610.1 - 0.011 14.5 0.1 0.015 14.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXX74610.1 - 0.023 14.0 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX74610.1 - 0.031 14.8 0.1 0.098 13.2 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXX74610.1 - 0.048 13.0 0.3 0.073 12.4 0.3 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KXX74610.1 - 0.071 12.2 0.1 0.22 10.6 0.0 1.7 2 1 0 2 2 2 0 Glucose inhibited division protein A Mqo PF06039.15 KXX74610.1 - 0.072 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) AMMECR1 PF01871.17 KXX74612.1 - 1.3e-45 155.0 0.0 3e-45 153.8 0.0 1.6 1 1 0 1 1 1 1 AMMECR1 PAP1 PF08601.10 KXX74612.1 - 0.0084 15.9 7.7 0.011 15.5 7.7 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 DUF1897 PF09005.10 KXX74612.1 - 0.056 12.9 0.4 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) DUF5342 PF17277.2 KXX74612.1 - 0.063 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5342) Ras PF00071.22 KXX74613.1 - 1.1e-38 132.4 0.0 5.5e-25 87.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXX74613.1 - 3.3e-11 43.4 0.0 7.2e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXX74613.1 - 0.0065 16.5 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXX74613.1 - 0.027 13.9 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.18 KXX74613.1 - 0.22 11.2 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Tma16 PF11176.8 KXX74614.1 - 8e-45 152.3 5.0 1e-44 152.0 5.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 HTH_32 PF13565.6 KXX74614.1 - 0.0026 18.3 3.1 0.26 11.9 0.1 2.2 2 0 0 2 2 2 2 Homeodomain-like domain MAM33 PF02330.16 KXX74615.1 - 1.3e-73 247.4 0.1 1.7e-73 247.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Polysacc_synt_4 PF04669.13 KXX74616.1 - 3.9e-14 52.6 0.4 1.4e-11 44.3 0.1 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis AChE_tetra PF08674.10 KXX74616.1 - 0.026 14.2 1.5 0.058 13.1 1.5 1.6 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Phageshock_PspG PF09583.10 KXX74617.1 - 0.06 13.6 1.3 0.06 13.6 1.3 3.4 4 0 0 4 4 4 0 Phage shock protein G (Phageshock_PspG) PQQ_3 PF13570.6 KXX74619.1 - 0.0033 17.8 2.3 4.2 8.0 0.1 4.6 4 1 0 4 4 4 2 PQQ-like domain ABC_membrane PF00664.23 KXX74620.1 - 1.5e-65 221.6 30.6 5e-38 131.3 11.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXX74620.1 - 2.4e-55 186.8 0.0 1.8e-26 93.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXX74620.1 - 9.4e-16 58.5 0.0 0.00044 20.1 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX74620.1 - 6e-15 55.3 0.1 1.3e-05 24.8 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXX74620.1 - 1.8e-09 38.0 0.0 0.0031 17.8 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KXX74620.1 - 3.4e-07 29.9 1.4 0.012 15.4 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXX74620.1 - 3.5e-06 27.5 1.7 0.07 13.5 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 KXX74620.1 - 3.1e-05 23.8 0.0 0.32 10.6 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KXX74620.1 - 4.2e-05 24.1 0.1 0.21 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXX74620.1 - 0.00013 22.0 0.1 0.35 10.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXX74620.1 - 0.0013 18.8 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 KXX74620.1 - 0.0013 18.3 5.3 2.2 7.8 0.1 3.9 4 0 0 4 4 4 2 AAA domain DUF3987 PF13148.6 KXX74620.1 - 0.0014 17.7 0.0 0.74 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_30 PF13604.6 KXX74620.1 - 0.0023 17.7 0.1 0.29 10.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXX74620.1 - 0.0038 17.4 0.1 4 7.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXX74620.1 - 0.0063 17.1 0.0 4.6 7.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXX74620.1 - 0.0072 16.3 0.3 3.1 7.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KXX74620.1 - 0.014 15.5 1.8 0.94 9.5 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_ATPase PF09818.9 KXX74620.1 - 0.022 13.6 0.1 0.24 10.2 0.0 2.6 3 1 0 3 3 3 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 KXX74620.1 - 0.023 13.9 0.1 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase3 PF18751.1 KXX74620.1 - 0.029 14.3 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KXX74620.1 - 0.057 13.8 0.1 6.5 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 KXX74620.1 - 0.069 13.0 0.1 39 4.1 0.0 3.2 3 0 0 3 3 3 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KXX74620.1 - 0.09 12.0 0.1 14 4.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF4438 PF14505.6 KXX74620.1 - 0.1 11.6 1.4 0.16 10.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) AAA PF00004.29 KXX74620.1 - 0.11 12.9 0.1 80 3.7 0.0 4.2 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXX74620.1 - 0.17 11.8 0.2 24 4.8 0.0 2.7 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 KXX74620.1 - 0.19 11.4 0.2 19 4.9 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein PRK PF00485.18 KXX74620.1 - 0.21 11.3 0.1 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family HET PF06985.11 KXX74622.1 - 1.4e-18 67.7 0.0 2.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 KXX74623.1 - 2.1e-48 165.0 0.1 2.4e-48 164.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 mRNA_triPase PF02940.15 KXX74624.1 - 2.5e-49 168.0 0.0 5.6e-49 166.8 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain DUF1769 PF08588.10 KXX74625.1 - 2.7e-28 97.9 0.6 5.2e-28 97.0 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) MFS_1 PF07690.16 KXX74626.1 - 2.8e-29 102.1 30.9 1.8e-26 92.9 15.4 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74626.1 - 1.7e-10 40.4 2.6 1.7e-10 40.4 2.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXX74626.1 - 2.5 6.3 6.9 0.64 8.2 1.1 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PRIMA1 PF16101.5 KXX74626.1 - 6.8 6.7 13.0 1.3 9.1 6.4 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF463 PF04317.12 KXX74627.1 - 0.018 14.0 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 RPN2_C PF18004.1 KXX74628.1 - 1e-57 194.5 4.7 1e-57 194.5 4.7 1.7 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KXX74628.1 - 7.3e-37 124.0 23.0 1.2e-08 35.0 0.0 8.8 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXX74628.1 - 9e-23 80.5 0.5 1.1e-14 54.5 0.0 5.5 6 0 0 6 6 6 3 HEAT repeats HEAT PF02985.22 KXX74628.1 - 7.9e-07 28.8 1.0 1.1 9.8 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KXX74628.1 - 2.9e-06 27.6 1.7 0.0023 18.4 0.0 5.1 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KXX74628.1 - 0.011 15.8 0.2 1.5 8.9 0.1 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 KXX74628.1 - 0.12 13.0 2.5 31 5.2 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF913 PF06025.12 KXX74628.1 - 7 5.5 6.0 26 3.6 4.8 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) adh_short_C2 PF13561.6 KXX74629.1 - 1.7e-49 168.5 0.0 2.3e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX74629.1 - 1e-37 129.5 0.0 1.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX74629.1 - 1.2e-06 28.6 0.3 1.9e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 KR domain HET PF06985.11 KXX74630.1 - 9.5e-35 120.1 0.1 1e-33 116.7 0.1 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_M23 PF01551.22 KXX74630.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 MR_MLE_C PF13378.6 KXX74631.1 - 1.3e-43 149.1 0.0 1.9e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXX74631.1 - 4.5e-10 39.8 0.0 7.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.15 KXX74631.1 - 0.19 11.0 0.0 0.68 9.2 0.0 1.7 2 0 0 2 2 2 0 Beta-galactosidase DUF3431 PF11913.8 KXX74632.1 - 3.8e-89 298.1 0.0 5.7e-89 297.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Methyltransf_25 PF13649.6 KXX74633.1 - 2e-09 38.1 0.1 3.9e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74633.1 - 1.9e-08 34.8 0.1 3.4e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74633.1 - 4.1e-08 33.2 0.0 5.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX74633.1 - 8e-07 29.0 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX74633.1 - 0.007 17.1 0.0 0.014 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX74633.1 - 0.0091 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXX74633.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) KR PF08659.10 KXX74633.1 - 0.014 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Tyrosinase PF00264.20 KXX74634.1 - 2.4e-46 158.8 0.0 4e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.18 KXX74635.1 - 2.6e-23 82.4 0.1 4e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX74635.1 - 1.8e-07 31.2 11.6 3e-07 30.4 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.26 KXX74636.1 - 3.9e-07 29.9 0.5 3e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Abhydrolase_1 PF00561.20 KXX74637.1 - 1.5e-13 51.0 0.0 1.7e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXX74637.1 - 5.5e-10 39.3 0.1 1.9e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein DUF5305 PF17231.2 KXX74638.1 - 0.0064 15.9 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) DUF2681 PF10883.8 KXX74638.1 - 0.016 15.6 0.3 0.027 14.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Med13_C PF06333.12 KXX74638.1 - 0.027 13.8 1.1 0.033 13.5 1.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF1772 PF08592.11 KXX74638.1 - 0.043 14.1 0.1 0.073 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) SKG6 PF08693.10 KXX74638.1 - 0.053 12.9 1.0 0.11 12.0 1.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF347 PF03988.12 KXX74638.1 - 0.063 13.5 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Med3 PF11593.8 KXX74638.1 - 0.61 9.2 6.4 0.83 8.8 6.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ZapB PF06005.12 KXX74639.1 - 0.0051 17.2 2.9 0.0051 17.2 2.9 3.9 4 1 0 4 4 4 1 Cell division protein ZapB Tropomyosin_1 PF12718.7 KXX74639.1 - 0.0079 16.4 26.6 0.019 15.1 22.4 2.8 1 1 2 3 3 3 1 Tropomyosin like Tropomyosin PF00261.20 KXX74639.1 - 0.14 11.5 28.2 0.067 12.6 20.8 2.3 1 1 1 2 2 2 0 Tropomyosin HAP1_N PF04849.13 KXX74639.1 - 0.6 9.3 34.1 2.7 7.1 0.4 3.2 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Phage_GP20 PF06810.11 KXX74639.1 - 0.77 9.6 12.8 0.84 9.4 1.3 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 Laminin_II PF06009.12 KXX74639.1 - 1.9 8.5 10.8 4 7.4 2.6 3.4 2 1 1 3 3 3 0 Laminin Domain II GAS PF13851.6 KXX74639.1 - 7.4 5.9 25.1 0.19 11.0 14.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KXX74639.1 - 7.7 6.7 24.6 4.6 7.4 1.7 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2293 PF10056.9 KXX74642.1 - 3.9e-31 107.1 0.4 3.9e-31 107.1 0.4 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) PROCN PF08083.11 KXX74643.1 - 4e-233 773.4 10.8 4e-233 773.4 10.8 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KXX74643.1 - 1.1e-126 421.1 1.3 2e-126 420.3 1.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KXX74643.1 - 3e-88 293.8 3.2 1e-87 292.0 1.9 2.6 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KXX74643.1 - 4.4e-79 263.7 2.7 4.4e-79 263.7 2.7 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KXX74643.1 - 4.2e-71 237.3 0.1 9e-71 236.2 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KXX74643.1 - 1e-46 157.8 0.6 2.8e-46 156.5 0.1 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 KXX74643.1 - 1.5e-46 156.7 0.1 4e-46 155.3 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Ribosomal_S11 PF00411.19 KXX74644.1 - 2e-46 156.9 1.2 2.4e-46 156.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KXX74644.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) BKACE PF05853.12 KXX74644.1 - 0.11 11.8 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme eIF-3c_N PF05470.12 KXX74645.1 - 5.8e-177 589.6 20.5 5.8e-177 589.6 20.5 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KXX74645.1 - 5.4e-14 52.6 0.7 6.6e-13 49.1 0.0 2.7 2 0 0 2 2 2 1 PCI domain Dynactin_p22 PF07426.11 KXX74645.1 - 0.00084 19.2 0.7 0.0039 17.1 0.7 2.2 1 0 0 1 1 1 1 Dynactin subunit p22 Ribosomal_L30_N PF08079.12 KXX74646.1 - 1.7e-28 98.7 18.3 2.9e-28 97.9 18.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KXX74646.1 - 5.6e-17 61.4 2.4 5.6e-17 61.4 2.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e MDM10 PF12519.8 KXX74647.1 - 1.2e-166 555.2 0.0 1.7e-139 465.7 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KXX74647.1 - 0.083 12.3 0.0 2.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic porin Fe-S_biosyn PF01521.20 KXX74648.1 - 1e-11 45.0 0.0 3.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Scytalone_dh PF02982.14 KXX74649.1 - 4.8e-92 306.0 1.0 5.4e-92 305.8 1.0 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KXX74649.1 - 3.1e-06 27.3 0.2 5.5e-06 26.5 0.2 1.4 1 1 0 1 1 1 1 SnoaL-like domain Ank_2 PF12796.7 KXX74650.1 - 2.5e-07 31.2 0.0 6.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX74650.1 - 9.7e-07 29.0 0.1 1.1e-05 25.6 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX74650.1 - 7.7e-05 23.2 0.0 0.00025 21.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXX74650.1 - 9.1e-05 22.7 0.1 0.001 19.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KXX74650.1 - 0.0025 18.2 0.0 0.021 15.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ribosomal_S19e PF01090.19 KXX74651.1 - 6.4e-59 197.6 0.6 7.4e-59 197.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e YkyA PF10368.9 KXX74651.1 - 0.02 14.6 1.2 0.034 13.8 1.2 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein SesA PF17107.5 KXX74652.1 - 6.2e-36 123.3 0.0 8.1e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 KXX74652.1 - 1.3e-11 44.4 12.2 2.2e-11 43.7 12.2 1.3 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases DUF2802 PF10975.8 KXX74652.1 - 0.032 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) SesA PF17107.5 KXX74653.1 - 1.2e-17 64.2 0.0 2.1e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 KXX74653.1 - 1.2e-06 28.6 6.9 2e-06 27.8 6.9 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases MCPVI PF02993.14 KXX74654.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Ricin_B_lectin PF00652.22 KXX74655.1 - 5.1e-15 55.9 0.0 3.7e-05 24.0 0.0 4.3 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain FIST_C PF10442.9 KXX74655.1 - 0.13 12.3 0.0 10 6.1 0.0 2.4 2 0 0 2 2 2 0 FIST C domain CDtoxinA PF03498.14 KXX74655.1 - 0.15 11.6 0.5 1.8 8.1 0.1 2.9 2 1 2 4 4 4 0 Cytolethal distending toxin A/C domain zf-C2H2_4 PF13894.6 KXX74658.1 - 0.006 17.3 3.1 2.3 9.3 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXX74658.1 - 0.0096 16.2 0.7 0.021 15.1 0.7 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon Phage_Gp23 PF10669.9 KXX74659.1 - 0.15 12.4 0.1 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DJ-1_PfpI PF01965.24 KXX74660.1 - 6.5e-13 48.8 0.0 9e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family p450 PF00067.22 KXX74662.1 - 4.6e-54 183.9 0.0 6.1e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CZB PF13682.6 KXX74662.1 - 0.16 12.4 0.1 0.53 10.8 0.1 1.8 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain CitMHS PF03600.16 KXX74663.1 - 1.4e-13 50.8 3.4 1.4e-13 50.8 3.4 1.7 2 1 0 2 2 2 1 Citrate transporter ArsB PF02040.15 KXX74663.1 - 4.3e-11 42.8 19.8 1.6e-07 31.0 8.1 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein HemY_N PF07219.13 KXX74663.1 - 4.6 7.5 11.1 3.6 7.8 0.2 3.6 3 0 0 3 3 3 0 HemY protein N-terminus Asp PF00026.23 KXX74664.1 - 1.4e-59 202.1 0.0 1.7e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX74664.1 - 1.4e-12 48.3 0.0 1.6e-08 35.0 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KXX74664.1 - 0.00013 21.8 0.1 0.028 14.2 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KXX74664.1 - 0.033 14.8 0.2 39 5.0 0.0 3.5 3 0 0 3 3 3 0 Aspartyl protease DUF2235 PF09994.9 KXX74665.1 - 1.2e-47 162.7 0.0 3.1e-47 161.3 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) EMG1 PF03587.14 KXX74666.1 - 3.9e-78 261.6 0.0 4.5e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase 2-oxoacid_dh PF00198.23 KXX74667.1 - 3e-81 272.3 0.1 4e-81 271.9 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXX74667.1 - 1.8e-17 63.0 1.0 4e-17 61.8 1.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KXX74667.1 - 0.00088 19.9 0.1 0.35 11.6 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KXX74667.1 - 0.001 18.8 0.1 0.19 11.6 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like DUF3614 PF12267.8 KXX74667.1 - 0.094 13.2 1.4 0.56 10.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) CCDC53 PF10152.9 KXX74667.1 - 0.57 10.6 4.9 1 9.7 4.9 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ndc1_Nup PF09531.10 KXX74667.1 - 1.1 7.9 3.1 1.4 7.6 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AA_permease PF00324.21 KXX74668.1 - 9.2e-60 202.6 33.6 2.5e-59 201.1 33.6 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX74668.1 - 5.6e-25 88.0 30.2 8.3e-25 87.5 30.2 1.2 1 0 0 1 1 1 1 Amino acid permease Focal_AT PF03623.13 KXX74668.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region Histone_H2A_C PF16211.5 KXX74669.1 - 2.2e-21 75.3 3.1 3.8e-21 74.5 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXX74669.1 - 7e-17 62.0 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXX74669.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXX74670.1 - 7.7e-21 74.8 1.6 9.7e-21 74.5 1.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXX74670.1 - 4.6e-05 23.6 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXX74670.1 - 0.00025 21.4 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 KXX74670.1 - 0.043 14.8 0.3 0.071 14.1 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 KXX74670.1 - 0.059 13.0 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 KXX74671.1 - 1.6e-13 50.4 0.0 3.5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KXX74671.1 - 1.3e-10 41.0 1.8 2.6e-10 40.0 1.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXX74671.1 - 0.76 9.9 4.6 0.15 12.2 0.5 2.0 2 0 0 2 2 2 0 G-patch domain Peptidase_C54 PF03416.19 KXX74672.1 - 2.6e-93 312.4 0.0 3.2e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.31 KXX74673.1 - 2.9e-23 81.8 0.4 2.9e-23 81.8 0.4 2.8 3 0 0 3 3 3 1 DnaJ domain zf-met PF12874.7 KXX74673.1 - 8.4e-11 41.9 10.0 5.4e-09 36.1 2.7 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXX74673.1 - 1.4e-10 41.1 4.4 1.4e-10 41.1 4.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXX74673.1 - 1.1e-07 32.2 7.4 0.00037 20.8 2.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXX74673.1 - 1.7e-05 25.2 6.4 0.039 14.8 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX74673.1 - 1.8e-05 24.9 9.2 0.042 14.3 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Actin_micro PF17003.5 KXX74673.1 - 0.001 18.3 2.2 0.0028 16.9 0.2 2.0 2 0 0 2 2 2 1 Putative actin-like family zf-C2H2_6 PF13912.6 KXX74673.1 - 0.0013 18.6 9.6 0.14 12.2 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KXX74673.1 - 0.011 16.4 1.0 7.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF2256 PF10013.9 KXX74673.1 - 0.013 15.6 5.0 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) RPT PF13446.6 KXX74673.1 - 0.019 14.9 0.0 0.088 12.7 0.0 2.1 1 1 1 2 2 2 0 A repeated domain in UCH-protein zf-H2C2_2 PF13465.6 KXX74673.1 - 0.098 13.1 2.0 5.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain SPX PF03105.19 KXX74674.1 - 2.5e-38 133.0 2.5 4.8e-25 89.3 1.0 2.1 1 1 1 2 2 2 2 SPX domain zf-C3HC4 PF00097.25 KXX74674.1 - 1e-05 25.3 13.8 2e-05 24.4 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX74674.1 - 4.6e-05 23.2 11.1 7.3e-05 22.6 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXX74674.1 - 0.0013 18.8 12.8 0.0024 18.0 12.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KXX74674.1 - 0.0014 18.9 14.0 0.0028 17.9 14.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXX74674.1 - 0.0022 17.9 11.3 0.0047 16.9 11.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain DUF4983 PF16356.5 KXX74674.1 - 0.011 16.5 0.1 0.029 15.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4983) zf-C3HC4_2 PF13923.6 KXX74674.1 - 0.013 15.3 13.7 0.023 14.6 13.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX74674.1 - 0.02 14.9 9.7 0.04 14.0 9.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KXX74674.1 - 0.023 14.5 4.5 0.05 13.4 4.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXX74674.1 - 0.03 14.2 10.2 0.061 13.2 10.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NOB1_Zn_bind PF08772.11 KXX74674.1 - 0.29 11.3 4.0 0.72 10.1 4.0 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Cys_Met_Meta_PP PF01053.20 KXX74675.1 - 7.1e-31 107.1 0.0 9.6e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Complex1_LYR PF05347.15 KXX74677.1 - 2e-10 40.6 2.1 2.7e-10 40.1 2.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) TFR_dimer PF04253.15 KXX74679.1 - 1.1e-33 115.9 0.1 2.5e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXX74679.1 - 7.9e-19 68.1 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXX74679.1 - 9.6e-11 41.6 0.4 2.6e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KXX74679.1 - 0.094 12.2 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Nicastrin BLOC1_2 PF10046.9 KXX74679.1 - 0.15 12.4 0.1 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RasGAP PF00616.19 KXX74680.1 - 3.6e-52 177.1 0.0 1e-51 175.6 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KXX74680.1 - 2e-48 164.0 2.9 2e-48 164.0 2.9 2.5 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 KXX74680.1 - 5.9e-18 62.9 31.8 0.073 12.9 0.7 13.5 14 0 0 14 14 14 7 IQ calmodulin-binding motif CH PF00307.31 KXX74680.1 - 3.4e-06 27.2 0.0 1.5e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain Ead_Ea22 PF13935.6 KXX74680.1 - 4.7 7.9 6.0 4.1 8.0 1.0 3.0 2 0 0 2 2 2 0 Ead/Ea22-like protein Sec7 PF01369.20 KXX74681.1 - 6.4e-29 100.9 0.3 1.2e-28 100.1 0.0 1.5 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KXX74681.1 - 9e-19 68.0 0.0 1.9e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DHHA1 PF02272.19 KXX74681.1 - 0.052 14.0 1.1 0.11 12.9 1.1 1.4 1 0 0 1 1 1 0 DHHA1 domain CTU2 PF10288.9 KXX74682.1 - 0.1 12.8 2.0 0.12 12.6 2.0 1.5 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 BUD22 PF09073.10 KXX74682.1 - 5.1 6.3 18.1 6 6.1 18.1 1.1 1 0 0 1 1 1 0 BUD22 IMPDH PF00478.25 KXX74683.1 - 1.9e-128 428.3 3.1 2.2e-128 428.1 3.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KXX74683.1 - 8.5e-16 58.2 0.1 1.1e-07 32.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KXX74683.1 - 5.7e-10 38.8 1.5 1.1e-07 31.2 0.8 2.4 2 0 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 KXX74683.1 - 1.3e-08 34.6 2.9 0.0028 17.1 4.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KXX74683.1 - 0.00027 20.5 2.7 0.01 15.3 0.4 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein YpsA PF06908.11 KXX74683.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family PK PF00224.21 KXX74683.1 - 0.057 12.3 0.0 0.26 10.1 0.0 2.0 2 1 1 3 3 3 0 Pyruvate kinase, barrel domain ThiG PF05690.14 KXX74683.1 - 0.12 11.6 2.2 0.11 11.8 0.5 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG AlaDh_PNT_N PF05222.15 KXX74684.1 - 3.6e-26 92.1 0.0 5.9e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KXX74684.1 - 0.0042 16.4 0.0 0.01 15.2 0.0 1.5 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain RP-C_C PF11800.8 KXX74685.1 - 0.13 12.3 0.2 0.29 11.2 0.1 1.5 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF4355 PF14265.6 KXX74685.1 - 0.18 12.1 0.4 0.32 11.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) MFS_1 PF07690.16 KXX74686.1 - 2.1e-33 115.7 35.9 3.9e-23 81.9 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74686.1 - 3.9e-09 35.9 5.2 3.9e-09 35.9 5.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXX74686.1 - 0.017 13.5 0.6 0.028 12.8 0.6 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Cnn_1N PF07989.11 KXX74687.1 - 6.7e-21 74.2 7.5 6.7e-21 74.2 7.5 11.8 9 4 2 11 11 11 4 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KXX74687.1 - 5.2e-09 36.3 11.7 5.2e-09 36.3 11.7 12.2 13 1 1 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region EzrA PF06160.12 KXX74687.1 - 2.3e-06 26.1 25.0 2.3e-06 26.1 25.0 5.2 3 2 1 5 5 5 1 Septation ring formation regulator, EzrA COG5 PF10392.9 KXX74687.1 - 0.00098 19.3 1.8 0.00098 19.3 1.8 8.0 6 4 2 8 8 8 1 Golgi transport complex subunit 5 DUF1640 PF07798.11 KXX74687.1 - 0.0084 16.2 14.0 0.0084 16.2 14.0 8.0 3 2 3 6 6 6 1 Protein of unknown function (DUF1640) NPV_P10 PF05531.12 KXX74687.1 - 0.082 13.4 0.0 0.082 13.4 0.0 7.2 7 2 1 8 8 8 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KXX74687.1 - 0.3 11.1 40.3 0.87 9.6 2.9 6.7 4 1 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus 2OG-FeII_Oxy PF03171.20 KXX74692.1 - 6.1e-15 55.5 0.0 1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXX74692.1 - 2.9e-09 37.7 0.0 4.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Amidohydro_3 PF07969.11 KXX74693.1 - 7.1e-13 48.8 0.2 3.4e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXX74693.1 - 3.2e-09 36.6 0.0 9.4e-08 31.7 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Neurensin PF14927.6 KXX74694.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Neurensin Fungal_trans PF04082.18 KXX74696.1 - 0.00018 20.6 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_TAF50 PF03326.13 KXX74696.1 - 1.6 7.3 7.6 2.4 6.7 7.6 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) p450 PF00067.22 KXX74697.1 - 1.5e-71 241.5 0.0 2e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KXX74698.1 - 6.1e-19 68.4 0.0 9.2e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74698.1 - 3e-08 34.2 0.0 7.2e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX74698.1 - 3.6e-08 34.1 0.0 1.2e-07 32.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74698.1 - 6.1e-06 26.1 0.0 0.0001 22.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74698.1 - 0.0014 19.2 0.0 0.0034 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXX74698.1 - 0.0023 17.4 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KXX74698.1 - 0.0027 17.1 0.0 0.032 13.6 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX74698.1 - 0.038 13.6 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.12 KXX74698.1 - 0.04 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF1735 PF08522.10 KXX74698.1 - 0.16 12.6 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Holin_2-3 PF13272.6 KXX74698.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative 2/3 transmembrane domain holin PLA2G12 PF06951.11 KXX74699.1 - 0.00016 21.6 4.3 0.00026 21.0 4.3 1.3 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) PIP49_C PF12260.8 KXX74699.1 - 0.011 15.3 1.0 0.021 14.5 1.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 FAD_binding_3 PF01494.19 KXX74700.1 - 8.8e-17 61.4 3.4 8.1e-16 58.2 3.4 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX74700.1 - 3.5e-13 49.9 0.8 3.3e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX74700.1 - 3.9e-07 29.6 0.0 0.0053 16.0 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX74700.1 - 7e-07 29.7 0.2 0.0039 17.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX74700.1 - 0.00061 20.0 0.2 0.00061 20.0 0.2 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KXX74700.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KXX74700.1 - 0.066 12.1 2.0 1.2 7.9 0.1 2.2 1 1 1 2 2 2 0 Tryptophan halogenase p450 PF00067.22 KXX74701.1 - 1.3e-46 159.4 0.0 2e-41 142.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CorA PF01544.18 KXX74702.1 - 1.3e-12 47.7 3.6 2.7e-12 46.6 3.6 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 KXX74702.1 - 0.00034 20.2 1.0 0.00059 19.4 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXX74702.1 - 0.027 13.7 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ni_hydr_CYTB PF01292.20 KXX74702.1 - 0.085 12.4 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Fib_alpha PF08702.10 KXX74702.1 - 0.45 10.7 5.1 1.6 8.9 5.1 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Surp PF01805.20 KXX74703.1 - 3.1e-11 43.1 0.0 7.3e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Surp module DAO PF01266.24 KXX74704.1 - 5.5e-41 141.3 0.9 6.7e-41 141.0 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXX74704.1 - 3.1e-06 27.3 0.1 0.0038 17.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXX74704.1 - 0.00022 20.6 0.0 0.43 9.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX74704.1 - 0.00036 20.7 0.1 0.0018 18.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXX74704.1 - 0.00049 19.3 0.0 0.0026 16.9 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXX74704.1 - 0.0016 17.4 0.0 0.3 9.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 KXX74704.1 - 0.01 16.4 0.0 0.029 14.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX74704.1 - 0.013 14.8 1.7 1.9 7.6 0.0 2.9 4 0 0 4 4 4 0 FAD binding domain FAD_binding_2 PF00890.24 KXX74704.1 - 0.02 14.0 0.1 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KXX74704.1 - 0.032 13.3 0.1 0.54 9.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 KXX74704.1 - 0.039 14.2 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ETF_QO PF05187.13 KXX74705.1 - 3.5e-47 158.8 0.6 5.9e-47 158.1 0.6 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KXX74705.1 - 2.6e-07 30.5 0.7 0.00011 22.0 0.5 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX74705.1 - 4.3e-07 30.1 0.0 1.3e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX74705.1 - 3.3e-05 23.3 0.0 8.1e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX74705.1 - 0.00021 20.5 0.4 0.0029 16.7 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXX74705.1 - 0.00021 20.1 0.4 0.00032 19.5 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KXX74705.1 - 0.0003 20.3 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXX74705.1 - 0.00093 18.1 0.0 0.17 10.7 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 KXX74705.1 - 0.00095 18.5 0.0 0.0046 16.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXX74705.1 - 0.0012 18.2 0.2 0.002 17.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXX74705.1 - 0.0018 18.3 0.1 0.0063 16.5 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXX74705.1 - 0.0031 18.0 0.2 4.2 8.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX74705.1 - 0.0074 15.6 0.3 0.01 15.1 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KXX74705.1 - 0.0081 16.7 1.1 0.022 15.3 1.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 KXX74705.1 - 0.022 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXX74705.1 - 0.033 13.3 0.2 0.053 12.6 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KXX74705.1 - 0.089 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 KXX74705.1 - 0.15 12.3 0.7 0.44 10.7 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain TBP PF00352.21 KXX74707.1 - 8.4e-68 224.4 0.1 7.1e-33 112.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KXX74707.1 - 0.00011 22.2 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KXX74707.1 - 0.13 12.1 0.1 0.68 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Metallothio_PEC PF02068.16 KXX74708.1 - 0.041 14.2 1.8 0.041 14.2 1.8 3.7 5 0 0 5 5 5 0 Plant PEC family metallothionein SUIM_assoc PF16619.5 KXX74709.1 - 3.4 7.8 8.2 8 6.6 8.2 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_16 PF10294.9 KXX74710.1 - 4.5e-08 33.0 0.0 1.3e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXX74710.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXX74710.1 - 0.17 12.6 0.0 7.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF3479 PF11965.8 KXX74710.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) SNF2_N PF00176.23 KXX74711.1 - 1.3e-68 231.3 1.4 1.4e-63 214.8 0.5 3.1 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX74711.1 - 2.8e-15 56.6 0.0 1.5e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX74711.1 - 3.8e-05 23.8 0.1 0.00012 22.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 KXX74711.1 - 2.4 7.7 5.1 1.3 8.6 0.0 2.5 2 1 0 2 2 2 0 DEAD_2 AA_permease_2 PF13520.6 KXX74712.1 - 5.5e-25 88.1 7.8 6.7e-25 87.8 7.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX74712.1 - 9e-08 31.1 4.9 1.2e-07 30.8 4.9 1.1 1 0 0 1 1 1 1 Amino acid permease EcsB PF05975.12 KXX74713.1 - 0.018 13.9 0.7 0.025 13.5 0.7 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Esterase PF00756.20 KXX74714.1 - 4e-08 33.2 0.0 5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXX74714.1 - 0.00024 20.6 0.1 0.00042 19.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXX74714.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PNP_UDP_1 PF01048.20 KXX74715.1 - 6.7e-14 51.7 2.2 3e-13 49.6 2.2 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT_sigma PF17106.5 KXX74715.1 - 0.012 15.7 17.4 0.012 15.7 17.4 2.4 3 0 0 3 3 3 0 Sigma domain on NACHT-NTPases NUP PF06516.11 KXX74715.1 - 0.049 12.9 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) NACHT PF05729.12 KXX74716.1 - 1.8e-09 37.8 0.1 6e-09 36.0 0.1 1.9 1 1 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 KXX74716.1 - 0.0002 21.9 0.0 0.0007 20.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXX74716.1 - 0.00051 20.5 0.0 0.0019 18.6 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain Ank_2 PF12796.7 KXX74716.1 - 0.0011 19.5 0.0 0.0033 18.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXX74716.1 - 0.0029 18.0 0.0 0.026 14.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.6 KXX74716.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX74716.1 - 0.03 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KXX74716.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXX74716.1 - 0.042 13.0 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KXX74716.1 - 0.095 13.3 0.0 0.26 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXX74716.1 - 0.1 12.2 0.1 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KXX74716.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.14 KXX74716.1 - 0.12 11.6 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 KXX74716.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT_sigma PF17106.5 KXX74716.1 - 0.17 12.1 18.2 0.41 10.8 18.2 1.6 1 0 0 1 1 1 0 Sigma domain on NACHT-NTPases DAP3 PF10236.9 KXX74716.1 - 0.19 10.9 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 BtrH_N PF14399.6 KXX74717.1 - 5.7e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Butirosin biosynthesis protein H, N-terminal Peptidase_C39 PF03412.15 KXX74717.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family Tyrosinase PF00264.20 KXX74718.1 - 1.3e-50 172.7 0.7 1.3e-50 172.7 0.7 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXX74718.1 - 1.2e-33 116.4 0.0 1.9e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain DUF4424 PF14415.6 KXX74718.1 - 0.046 13.0 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) Ser_hydrolase PF06821.13 KXX74718.1 - 0.089 12.6 0.9 0.41 10.5 0.9 2.0 1 1 0 1 1 1 0 Serine hydrolase WBS_methylT PF12589.8 KXX74719.1 - 4.6e-14 52.9 5.0 8.3e-14 52.1 5.0 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KXX74719.1 - 4.5e-11 43.2 0.0 8.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74719.1 - 1.5e-09 38.5 0.0 3.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXX74719.1 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KXX74719.1 - 0.00018 22.2 0.0 0.00055 20.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74719.1 - 0.00092 19.0 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXX74719.1 - 0.0029 17.0 0.0 0.028 13.7 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXX74719.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXX74719.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FMO-like PF00743.19 KXX74720.1 - 3.2e-16 58.9 0.0 2.5e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXX74720.1 - 3.9e-10 39.4 0.0 2.6e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX74720.1 - 1.8e-08 34.4 0.3 2.2e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXX74720.1 - 8.1e-08 32.4 0.3 1.5e-06 28.3 0.1 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXX74720.1 - 1.6e-06 27.5 0.0 4.4e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXX74720.1 - 3.1e-06 26.7 0.0 0.00077 18.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX74720.1 - 0.00028 20.6 0.1 0.0063 16.1 0.0 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX74720.1 - 0.011 16.3 0.2 5.9 7.5 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX74720.1 - 0.012 14.4 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.24 KXX74720.1 - 0.013 14.8 0.0 0.053 12.8 0.0 2.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXX74720.1 - 0.034 13.4 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KXX74720.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain 7tm_2 PF00002.24 KXX74721.1 - 3e-12 46.4 9.3 5.2e-12 45.6 9.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KXX74721.1 - 7e-09 35.2 7.8 1.5e-08 34.1 7.8 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KXX74721.1 - 1.4e-06 28.3 12.4 2.7e-06 27.3 12.4 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 TMEM190 PF15431.6 KXX74721.1 - 0.075 13.2 3.2 0.34 11.1 0.7 2.8 2 1 1 3 3 3 0 Transmembrane protein 190 TMEMspv1-c74-12 PF11044.8 KXX74721.1 - 0.23 11.5 0.3 9.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TPR_10 PF13374.6 KXX74722.1 - 1.2e-53 177.6 0.8 3.6e-12 45.7 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXX74722.1 - 5.4e-43 145.2 5.0 2.8e-14 53.1 0.0 4.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXX74722.1 - 1.1e-16 59.5 1.4 0.0056 16.6 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KXX74722.1 - 2.1e-12 46.8 0.1 3.8e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_2 PF07719.17 KXX74722.1 - 1.9e-08 33.8 1.5 0.079 13.1 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXX74722.1 - 2.4e-08 33.8 6.5 0.15 12.8 0.1 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXX74722.1 - 2.8e-08 34.1 0.0 6.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 KXX74722.1 - 5e-08 32.4 0.1 0.79 9.7 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXX74722.1 - 1.2e-06 28.5 0.0 2.6 8.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX74722.1 - 9.3e-06 25.2 3.2 3.3e-05 23.4 3.2 1.9 1 1 0 1 1 1 1 MalT-like TPR region AAA_16 PF13191.6 KXX74722.1 - 0.00012 22.6 0.8 0.001 19.5 0.8 2.7 1 1 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.6 KXX74722.1 - 0.0018 18.8 1.3 64 4.2 0.1 5.0 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX74722.1 - 0.003 17.7 0.1 12 6.4 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXX74722.1 - 0.0038 17.8 0.2 0.62 10.7 0.0 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 KXX74722.1 - 0.0062 15.7 0.0 0.047 12.9 0.0 2.4 3 0 0 3 3 3 1 NB-ARC domain N1221 PF07923.13 KXX74722.1 - 0.022 14.0 0.3 1.4 8.0 0.1 2.4 1 1 1 2 2 2 0 N1221-like protein IstB_IS21 PF01695.17 KXX74722.1 - 0.023 14.4 0.2 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXX74722.1 - 0.039 13.3 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KXX74722.1 - 0.13 12.7 0.0 3.7 8.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.20 KXX74723.1 - 5.6e-21 74.5 0.0 6.2e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXX74723.1 - 0.0014 18.9 0.1 0.03 14.6 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXX74723.1 - 0.0034 17.8 0.1 0.25 11.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXX74723.1 - 0.0044 16.4 0.0 0.0049 16.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KXX74723.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KXX74723.1 - 0.024 14.8 0.0 0.032 14.4 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KXX74723.1 - 0.11 12.1 0.3 0.32 10.7 0.3 1.7 1 1 1 2 2 2 0 Redoxin Erv26 PF04148.13 KXX74725.1 - 3.5e-96 320.9 0.1 3.9e-96 320.8 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.8 KXX74725.1 - 0.017 15.0 0.2 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) TMEM43 PF07787.12 KXX74725.1 - 0.33 10.3 3.1 0.53 9.6 3.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 DnaJ PF00226.31 KXX74726.1 - 2.9e-23 81.8 0.4 2.9e-23 81.8 0.4 2.8 3 0 0 3 3 3 1 DnaJ domain zf-met PF12874.7 KXX74726.1 - 8.4e-11 41.9 10.0 5.4e-09 36.1 2.7 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXX74726.1 - 1.4e-10 41.1 4.4 1.4e-10 41.1 4.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXX74726.1 - 1.1e-07 32.2 7.4 0.00037 20.8 2.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXX74726.1 - 1.7e-05 25.2 6.4 0.039 14.8 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX74726.1 - 1.8e-05 24.9 9.2 0.042 14.3 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Actin_micro PF17003.5 KXX74726.1 - 0.001 18.3 2.2 0.0028 16.9 0.2 2.0 2 0 0 2 2 2 1 Putative actin-like family zf-C2H2_6 PF13912.6 KXX74726.1 - 0.0013 18.6 9.6 0.14 12.2 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KXX74726.1 - 0.011 16.4 1.0 7.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF2256 PF10013.9 KXX74726.1 - 0.013 15.6 5.0 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) RPT PF13446.6 KXX74726.1 - 0.019 14.9 0.0 0.088 12.7 0.0 2.1 1 1 1 2 2 2 0 A repeated domain in UCH-protein zf-H2C2_2 PF13465.6 KXX74726.1 - 0.098 13.1 2.0 5.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain 2-oxoacid_dh PF00198.23 KXX74727.1 - 3e-81 272.3 0.1 4e-81 271.9 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXX74727.1 - 1.8e-17 63.0 1.0 4e-17 61.8 1.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KXX74727.1 - 0.00088 19.9 0.1 0.35 11.6 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KXX74727.1 - 0.001 18.8 0.1 0.19 11.6 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like DUF3614 PF12267.8 KXX74727.1 - 0.094 13.2 1.4 0.56 10.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) CCDC53 PF10152.9 KXX74727.1 - 0.57 10.6 4.9 1 9.7 4.9 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ndc1_Nup PF09531.10 KXX74727.1 - 1.1 7.9 3.1 1.4 7.6 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Complex1_LYR PF05347.15 KXX74728.1 - 2e-10 40.6 2.1 2.7e-10 40.1 2.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) AA_permease PF00324.21 KXX74730.1 - 9.2e-60 202.6 33.6 2.5e-59 201.1 33.6 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX74730.1 - 5.6e-25 88.0 30.2 8.3e-25 87.5 30.2 1.2 1 0 0 1 1 1 1 Amino acid permease Focal_AT PF03623.13 KXX74730.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region R3H PF01424.22 KXX74731.1 - 1.6e-13 50.4 0.0 3.5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KXX74731.1 - 1.3e-10 41.0 1.8 2.6e-10 40.0 1.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXX74731.1 - 0.76 9.9 4.6 0.15 12.2 0.5 2.0 2 0 0 2 2 2 0 G-patch domain Peptidase_C54 PF03416.19 KXX74732.1 - 2.6e-93 312.4 0.0 3.2e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone_H2A_C PF16211.5 KXX74733.1 - 2.2e-21 75.3 3.1 3.8e-21 74.5 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXX74733.1 - 7e-17 62.0 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXX74733.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXX74734.1 - 7.7e-21 74.8 1.6 9.7e-21 74.5 1.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXX74734.1 - 4.6e-05 23.6 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXX74734.1 - 0.00025 21.4 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 KXX74734.1 - 0.043 14.8 0.3 0.071 14.1 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 KXX74734.1 - 0.059 13.0 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain OTU PF02338.19 KXX74735.1 - 3.1e-06 27.7 0.0 5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 KXX74735.1 - 0.003 18.0 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UBX PF00789.20 KXX74735.1 - 0.0032 17.6 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain PB1 PF00564.24 KXX74735.1 - 0.037 13.9 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 PB1 domain Bromodomain PF00439.25 KXX74736.1 - 6.2e-43 144.8 0.3 3.9e-20 71.7 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KXX74736.1 - 1.3e-18 67.0 1.6 1.9e-18 66.5 0.3 2.1 2 0 0 2 2 2 1 BAH domain AT_hook PF02178.19 KXX74736.1 - 1.1 9.3 11.7 0.21 11.6 1.0 3.2 2 0 0 2 2 2 0 AT hook motif Mito_carr PF00153.27 KXX74738.1 - 2.9e-45 152.1 3.2 8.5e-19 67.3 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Rad54_N PF08658.10 KXX74739.1 - 2.9e-58 197.0 1.5 1e-57 195.2 1.5 1.9 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 KXX74739.1 - 3e-58 197.2 0.0 5.7e-58 196.3 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX74739.1 - 4.3e-15 56.0 0.0 1.1e-14 54.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX74739.1 - 2.7e-08 34.0 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXX74739.1 - 9.6e-05 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KXX74739.1 - 0.0015 17.8 0.0 0.0066 15.6 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KXX74739.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Glyco_transf_24 PF18404.1 KXX74740.1 - 1.2e-148 493.7 2.5 1.8e-148 493.2 2.5 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KXX74740.1 - 9.6e-66 222.3 0.0 2.2e-64 217.9 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KXX74740.1 - 4.8e-55 186.8 0.4 2.4e-53 181.2 0.3 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KXX74740.1 - 1.1e-46 159.1 0.1 2.5e-46 158.0 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KXX74740.1 - 1.8e-46 157.4 0.2 2.3e-45 153.8 0.1 2.8 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KXX74740.1 - 3.6e-43 146.1 0.0 7.1e-43 145.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KXX74740.1 - 0.00012 21.7 0.2 0.00026 20.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 adh_short PF00106.25 KXX74741.1 - 1.5e-33 115.9 0.4 5.5e-33 114.1 0.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX74741.1 - 4.6e-24 85.3 3.8 2.4e-23 82.9 3.8 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX74741.1 - 2e-07 31.1 0.0 3.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX74741.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KXX74741.1 - 0.34 10.7 2.2 0.78 9.5 0.5 2.4 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Apt1 PF10351.9 KXX74742.1 - 0.28 10.0 12.6 0.43 9.4 12.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KXX74742.1 - 0.37 9.5 0.9 0.66 8.7 0.9 1.3 1 0 0 1 1 1 0 Presenilin Coatomer_WDAD PF04053.14 KXX74743.1 - 1.8e-145 485.4 0.0 2.7e-145 484.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KXX74743.1 - 2.4e-97 326.3 0.0 3.2e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KXX74743.1 - 9.3e-37 124.4 15.5 1.7e-07 31.8 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74743.1 - 3.1e-09 37.0 0.9 0.00014 22.0 0.0 5.6 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX74743.1 - 0.048 12.3 5.6 5.4 5.5 0.0 3.9 3 1 1 4 4 4 0 Nucleoporin Nup120/160 CSN8_PSD8_EIF3K PF10075.9 KXX74744.1 - 7.1e-17 61.7 0.0 1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Sel1 PF08238.12 KXX74745.1 - 9.6e-22 76.9 29.8 5.5e-07 30.1 0.2 7.5 7 0 0 7 7 7 6 Sel1 repeat TPR_1 PF00515.28 KXX74745.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KXX74745.1 - 4.1 7.6 6.7 25 5.0 0.8 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KXX74745.1 - 6.7 7.6 8.9 6.2 7.7 0.1 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 KXX74746.1 - 6.4e-45 151.0 4.4 9.1e-15 54.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_A25 PF03418.14 KXX74746.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Germination protease Myb_DNA-bind_2 PF08914.11 KXX74747.1 - 9.4e-27 93.0 9.6 2e-17 63.1 2.1 2.6 2 0 0 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 KXX74747.1 - 1.9e-21 75.9 1.0 1.2e-16 60.6 0.0 3.7 3 0 0 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.10 KXX74747.1 - 4.4e-08 33.7 4.1 0.0016 19.0 0.3 2.9 2 0 0 2 2 2 2 Rap1, DNA-binding BRCT_2 PF16589.5 KXX74747.1 - 1.4e-06 28.6 0.0 4e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain ARID PF01388.21 KXX74747.1 - 0.00062 20.4 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Myb_DNA-binding PF00249.31 KXX74747.1 - 0.19 12.0 5.5 1.1 9.5 0.2 4.0 4 0 0 4 4 4 0 Myb-like DNA-binding domain IQ PF00612.27 KXX74747.1 - 0.32 10.9 20.6 0.79 9.7 3.5 3.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif HET PF06985.11 KXX74749.1 - 1.2e-23 84.1 0.0 2e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CytadhesinP1 PF12378.8 KXX74749.1 - 0.36 11.0 1.8 0.58 10.4 0.3 2.0 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein MFS_1 PF07690.16 KXX74750.1 - 8.1e-25 87.5 28.6 8.1e-25 87.5 28.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74750.1 - 1.3e-05 24.3 6.0 1.3e-05 24.3 6.0 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KXX74750.1 - 0.023 13.0 3.1 0.027 12.8 0.2 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SAYSvFN PF10260.9 KXX74750.1 - 0.28 11.1 2.9 0.48 10.4 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) ADH_zinc_N PF00107.26 KXX74751.1 - 2e-15 56.9 0.0 3.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX74751.1 - 7.7e-15 56.1 0.0 1.5e-14 55.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX74751.1 - 7.4e-05 22.6 0.2 0.012 15.5 0.1 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 KXX74751.1 - 0.017 15.0 0.4 0.029 14.2 0.4 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Complex1_LYR_2 PF13233.6 KXX74752.1 - 3.1e-22 79.1 0.1 3.6e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXX74752.1 - 0.017 15.1 0.4 0.036 14.1 0.4 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DHHC PF01529.20 KXX74753.1 - 8e-30 103.7 4.9 8e-30 103.7 4.9 2.2 3 1 0 3 3 3 1 DHHC palmitoyltransferase MMR_HSR1 PF01926.23 KXX74754.1 - 1e-15 57.8 0.0 3.4e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXX74754.1 - 4.9e-08 32.8 0.1 2e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXX74754.1 - 8e-05 22.2 0.0 0.0048 16.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXX74754.1 - 8.2e-05 22.6 0.0 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KXX74754.1 - 0.00026 21.1 0.0 0.18 11.9 0.0 2.6 3 0 0 3 3 3 2 Dynamin family TniB PF05621.11 KXX74754.1 - 0.03 13.7 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KXX74754.1 - 0.038 13.7 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 KXX74754.1 - 0.046 13.1 0.0 6.2 6.1 0.1 2.2 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.27 KXX74754.1 - 0.055 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 KXX74754.1 - 0.069 12.4 0.0 0.68 9.2 0.0 2.0 1 1 0 1 1 1 0 Septin Roc PF08477.13 KXX74754.1 - 0.19 11.9 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase tRNA-synt_1 PF00133.22 KXX74756.1 - 9.1e-197 655.0 0.0 1.2e-196 654.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXX74756.1 - 2.6e-24 85.9 0.0 6.6e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXX74756.1 - 2.9e-15 55.9 0.7 2.3e-05 23.4 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KXX74756.1 - 0.00039 19.9 0.0 0.0056 16.1 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF463 PF04317.12 KXX74757.1 - 0.27 10.1 0.0 0.41 9.5 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 HET PF06985.11 KXX74758.1 - 1.4e-23 83.9 0.1 7.7e-23 81.5 0.1 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRN3 PF05327.11 KXX74758.1 - 0.076 11.5 0.2 0.1 11.1 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HD PF01966.22 KXX74759.1 - 0.00022 21.4 0.1 0.00033 20.9 0.1 1.4 1 0 0 1 1 1 1 HD domain Glyco_hydro_2_C PF02836.17 KXX74760.1 - 2.1e-25 89.5 0.0 1.1e-24 87.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 KXX74760.1 - 1.3e-11 44.3 0.0 1.4e-10 40.9 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 KXX74760.1 - 4.6e-08 33.1 0.0 1.8e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.6 KXX74760.1 - 0.1 13.2 0.0 0.61 10.7 0.0 2.3 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain AA_permease_2 PF13520.6 KXX74761.1 - 2.9e-49 168.0 48.3 3.8e-49 167.7 48.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX74761.1 - 1.4e-29 103.1 42.3 1.7e-29 102.8 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease UQ_con PF00179.26 KXX74763.1 - 4.1e-13 49.2 0.0 8.1e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.7 KXX74763.1 - 0.0005 19.9 0.4 0.0048 16.8 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXX74763.1 - 0.0025 17.6 0.5 0.0063 16.4 0.5 1.7 1 0 0 1 1 1 1 F-box domain TilS PF09179.11 KXX74763.1 - 0.084 13.4 0.7 53 4.4 0.1 3.9 4 0 0 4 4 4 0 TilS substrate binding domain PBP PF01161.20 KXX74765.1 - 0.00017 21.9 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_7 PF00840.20 KXX74766.1 - 1.8e-185 616.8 9.8 2e-185 616.6 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF2985 PF11204.8 KXX74767.1 - 2.1e-20 72.6 3.7 4e-20 71.7 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) ketoacyl-synt PF00109.26 KXX74769.1 - 4e-67 226.5 0.0 4.8e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXX74769.1 - 3.4e-08 33.5 0.1 1.1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXX74769.1 - 7.4e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KXX74769.1 - 0.0002 21.1 0.6 0.00047 20.0 0.6 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III KR PF08659.10 KXX74770.1 - 5.6e-60 202.3 0.2 1.5e-59 201.0 0.2 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXX74770.1 - 1.6e-48 165.9 0.0 2.7e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXX74770.1 - 3.5e-43 147.9 0.1 5.7e-43 147.3 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 KXX74770.1 - 1.6e-16 60.9 0.0 5e-16 59.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXX74770.1 - 1.6e-14 54.3 0.1 1e-07 32.4 0.0 3.8 4 0 0 4 4 3 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KXX74770.1 - 3.1e-14 53.0 0.0 9.7e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXX74770.1 - 2.2e-13 50.1 0.0 5.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KXX74770.1 - 5.8e-12 46.8 0.0 2.4e-11 44.8 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KXX74770.1 - 2.1e-11 43.9 0.0 4.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74770.1 - 1.3e-08 35.4 0.0 1.1e-07 32.5 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain adh_short_C2 PF13561.6 KXX74770.1 - 1.4e-08 34.6 0.0 4.8e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KXX74770.1 - 5.1e-08 32.9 0.0 9.6e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74770.1 - 1.5e-07 32.0 0.0 6.6e-07 29.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXX74770.1 - 5.1e-07 29.9 0.0 1.9e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KXX74770.1 - 0.00052 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NmrA PF05368.13 KXX74770.1 - 0.0037 16.8 0.0 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family DREV PF05219.12 KXX74770.1 - 0.024 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.17 KXX74770.1 - 0.037 13.7 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PK_C PF02887.16 KXX74770.1 - 0.049 13.8 0.1 2.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain NodS PF05401.11 KXX74770.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF915 PF06028.11 KXX74770.1 - 0.13 11.5 0.0 1 8.6 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Tautomerase_2 PF14552.6 KXX74770.1 - 0.2 11.8 0.1 7.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Tautomerase enzyme p450 PF00067.22 KXX74771.1 - 2.4e-55 188.1 0.0 3.9e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 KXX74772.1 - 3.2e-22 78.8 0.0 4.3e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family Pyr_redox_2 PF07992.14 KXX74774.1 - 1.5e-48 165.6 2.2 2.1e-48 165.0 2.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXX74774.1 - 8.3e-16 57.7 0.0 1.9e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KXX74774.1 - 3.5e-13 49.9 1.3 1.7e-11 44.5 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX74774.1 - 6.9e-07 28.8 0.0 0.0072 15.6 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KXX74774.1 - 6.7e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KXX74774.1 - 5.9e-05 23.0 0.0 0.00022 21.1 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 KXX74774.1 - 0.0058 16.6 0.9 3.7 7.5 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXX74774.1 - 0.007 15.5 0.0 1.6 7.8 0.1 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_3 PF07859.13 KXX74775.1 - 1.5e-41 142.6 0.0 2e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXX74775.1 - 2.3e-06 26.8 0.9 2.1e-05 23.6 0.9 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXX74775.1 - 0.00025 21.7 1.2 0.00038 21.1 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXX74775.1 - 0.033 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1989 PF09347.10 KXX74776.1 - 6.2e-53 178.8 0.0 1.8e-28 99.3 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1989) Sugar_tr PF00083.24 KXX74778.1 - 2.3e-80 270.7 24.4 2.6e-80 270.5 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX74778.1 - 9.4e-27 93.8 19.6 9.4e-27 93.8 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX74778.1 - 0.0002 19.9 1.7 0.0003 19.3 1.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TFIIB PF00382.19 KXX74779.1 - 0.055 13.5 0.0 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Dynamin_N PF00350.23 KXX74780.1 - 7.5e-15 55.4 1.7 1.6e-13 51.1 0.0 2.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXX74780.1 - 0.00053 20.1 0.0 0.0082 16.2 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXX74780.1 - 0.00093 19.7 0.2 0.013 16.0 0.0 2.7 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KXX74780.1 - 0.01 15.8 0.0 0.095 12.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Prominin PF05478.11 KXX74780.1 - 0.016 13.2 5.6 0.27 9.2 0.1 2.8 3 0 0 3 3 3 0 Prominin LPP PF04728.13 KXX74780.1 - 0.066 13.6 8.9 0.45 10.9 0.1 4.5 4 0 0 4 4 4 0 Lipoprotein leucine-zipper AAA_22 PF13401.6 KXX74780.1 - 0.12 12.7 0.0 2 8.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX74780.1 - 0.26 11.7 5.5 0.42 11.0 0.0 3.9 4 1 0 4 4 4 0 AAA ATPase domain DUF3450 PF11932.8 KXX74780.1 - 0.79 9.0 11.2 9.5 5.4 7.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KXX74780.1 - 0.86 10.1 22.2 1.2 9.7 9.9 4.5 4 0 0 4 4 4 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KXX74780.1 - 0.92 10.0 4.2 25 5.5 0.0 3.8 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.12 KXX74780.1 - 2.8 8.3 7.9 50 4.2 0.6 4.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 KXX74780.1 - 3.5 7.7 14.9 31 4.6 2.7 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) ZapB PF06005.12 KXX74780.1 - 4.8 7.7 13.7 32 5.1 0.0 3.9 3 0 0 3 3 3 0 Cell division protein ZapB ARL2_Bind_BART PF11527.8 KXX74780.1 - 4.9 7.3 6.3 0.77 9.9 0.1 2.9 5 0 0 5 5 4 0 The ARF-like 2 binding protein BART RR_TM4-6 PF06459.12 KXX74780.1 - 6.8 6.4 11.8 20 4.9 11.8 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fungal_trans PF04082.18 KXX74781.1 - 2.6e-30 105.3 0.0 6.9e-30 104.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX74781.1 - 1.4e-08 34.7 8.6 2.3e-08 34.0 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX74781.1 - 0.023 13.5 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain TAF4 PF05236.14 KXX74781.1 - 0.62 9.8 10.9 2.3 7.9 9.2 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Sugar_tr PF00083.24 KXX74782.1 - 1e-121 407.0 27.2 1.2e-121 406.8 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX74782.1 - 2.6e-20 72.7 47.8 2.5e-15 56.3 18.7 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily DUF2781 PF10914.8 KXX74782.1 - 0.013 15.9 3.2 0.013 15.9 3.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2781) Mucin PF01456.17 KXX74783.1 - 0.0047 16.9 17.9 0.0047 16.9 17.9 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein DAGK_cat PF00781.24 KXX74784.1 - 5.3e-10 39.0 0.1 1.1e-09 37.9 0.1 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain GGDEF PF00990.21 KXX74784.1 - 0.013 15.2 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Diguanylate cyclase, GGDEF domain SH3_4 PF06347.13 KXX74784.1 - 0.58 10.0 6.4 4 7.4 0.3 2.6 1 1 1 2 2 2 0 Bacterial SH3 domain ABC_tran PF00005.27 KXX74785.1 - 7.7e-45 152.8 1.3 1.5e-20 74.1 0.0 3.7 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KXX74785.1 - 1.5e-13 51.2 6.2 0.0003 20.7 0.0 4.6 5 0 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX74785.1 - 7.5e-10 38.6 0.0 0.0014 18.1 0.0 4.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KXX74785.1 - 3.7e-09 36.5 5.4 8.8e-09 35.3 5.4 1.6 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 KXX74785.1 - 3.9e-09 36.6 0.3 0.00079 19.5 0.0 3.2 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXX74785.1 - 2.5e-08 33.5 0.2 0.00032 20.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX74785.1 - 5.9e-06 26.6 0.4 0.11 12.7 0.1 3.4 3 2 0 3 3 2 2 AAA domain NACHT PF05729.12 KXX74785.1 - 8.3e-06 25.8 0.0 0.013 15.5 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 KXX74785.1 - 2.1e-05 25.1 11.2 0.0062 17.1 0.6 3.5 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXX74785.1 - 2.2e-05 24.4 2.0 0.25 11.2 0.1 3.1 3 1 0 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 KXX74785.1 - 7.8e-05 23.0 0.8 0.057 13.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 KXX74785.1 - 9e-05 22.7 2.8 0.53 10.3 0.0 3.4 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_33 PF13671.6 KXX74785.1 - 0.0001 22.4 2.5 0.65 10.2 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KXX74785.1 - 0.00011 22.8 1.0 0.95 10.0 0.0 3.2 4 1 0 4 4 2 2 AAA domain AAA_16 PF13191.6 KXX74785.1 - 0.00022 21.7 7.7 0.14 12.5 0.8 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 KXX74785.1 - 0.00026 19.8 1.8 1.4 7.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain MeaB PF03308.16 KXX74785.1 - 0.00067 18.7 0.5 0.61 9.0 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KXX74785.1 - 0.00093 19.0 1.8 0.044 13.5 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain cobW PF02492.19 KXX74785.1 - 0.0025 17.4 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KXX74785.1 - 0.0061 16.9 0.0 1.6 9.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 KXX74785.1 - 0.0071 16.6 0.0 3.3 8.0 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 KXX74785.1 - 0.014 15.0 6.5 0.035 13.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain ABC_ATPase PF09818.9 KXX74785.1 - 0.015 14.1 0.0 0.071 11.9 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class G-alpha PF00503.20 KXX74785.1 - 0.019 14.1 0.3 0.72 8.9 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit Viral_helicase1 PF01443.18 KXX74785.1 - 0.027 14.2 0.0 10 5.8 0.0 2.9 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KXX74785.1 - 0.028 13.6 5.2 1.1 8.4 0.0 3.5 4 0 0 4 4 3 0 NB-ARC domain AAA_14 PF13173.6 KXX74785.1 - 0.029 14.4 0.1 4.7 7.3 0.0 3.2 4 0 0 4 4 2 0 AAA domain Zeta_toxin PF06414.12 KXX74785.1 - 0.031 13.6 0.1 1.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 KXX74785.1 - 0.032 14.3 1.6 4.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Dynamin family Arf PF00025.21 KXX74785.1 - 0.037 13.5 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF815 PF05673.13 KXX74785.1 - 0.04 13.1 0.1 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 KXX74785.1 - 0.045 14.2 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KXX74785.1 - 0.052 13.5 0.0 3.1 7.7 0.0 2.9 3 0 0 3 3 3 0 NTPase ATPase_2 PF01637.18 KXX74785.1 - 0.052 13.4 0.4 1.9 8.4 0.0 2.5 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KXX74785.1 - 0.054 13.5 0.1 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 KXX74785.1 - 0.069 12.9 0.5 0.73 9.6 0.0 2.6 2 1 1 3 3 3 0 MukB N-terminal AAA_5 PF07728.14 KXX74785.1 - 0.089 12.8 0.2 1.8 8.6 0.0 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXX74785.1 - 0.11 12.2 0.0 9.8 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXX74785.1 - 0.11 12.2 8.4 0.94 9.2 0.0 4.0 4 1 0 4 4 3 0 AAA domain AAA_25 PF13481.6 KXX74785.1 - 0.14 11.7 2.5 1.5 8.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Adeno_IVa2 PF02456.15 KXX74785.1 - 0.15 10.8 0.3 4.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein Thymidylate_kin PF02223.17 KXX74785.1 - 0.24 11.0 2.9 8.8 6.0 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase FtsK_SpoIIIE PF01580.18 KXX74785.1 - 0.27 10.6 4.1 1.9 7.8 0.1 3.2 2 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.6 KXX74785.1 - 0.32 11.4 7.4 6.1 7.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain DNA_topoisoIV PF00521.20 KXX74786.1 - 8.4e-123 410.4 0.0 1.5e-122 409.5 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KXX74786.1 - 1.7e-43 147.9 4.6 1.7e-43 147.9 4.6 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KXX74786.1 - 1.3e-24 86.7 1.3 2.5e-24 85.7 1.3 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KXX74786.1 - 3.1e-13 50.2 0.0 1.1e-12 48.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KXX74786.1 - 9.4e-06 25.8 0.0 3.5e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 KXX74786.1 - 0.00011 22.1 0.3 0.00032 20.5 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_transp_aux PF09822.9 KXX74786.1 - 0.072 12.5 1.3 0.39 10.1 0.1 2.4 2 0 0 2 2 2 0 ABC-type uncharacterized transport system TRM PF02005.16 KXX74787.1 - 1.2e-100 337.3 0.0 5.1e-100 335.3 0.0 1.9 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase SPATA3 PF15662.5 KXX74787.1 - 0.72 10.5 5.1 1.5 9.5 5.1 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family TPR_1 PF00515.28 KXX74788.1 - 6.8e-09 35.2 4.3 0.011 15.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX74788.1 - 8.7e-08 31.7 5.8 0.12 12.6 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX74788.1 - 0.0039 17.4 2.4 0.0096 16.1 2.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXX74788.1 - 0.012 16.1 3.9 0.047 14.2 3.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX74788.1 - 0.019 15.2 0.5 0.71 10.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SAPIS-gp6 PF16722.5 KXX74788.1 - 0.15 12.4 0.4 0.37 11.2 0.4 1.6 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus TPR_17 PF13431.6 KXX74788.1 - 0.27 11.7 2.4 0.49 10.9 0.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KXX74790.1 - 6.8e-08 32.2 0.0 1.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74790.1 - 2.7e-05 23.6 0.0 0.00017 21.0 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase p450 PF00067.22 KXX74791.1 - 5.2e-58 196.9 0.0 7.1e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KXX74792.1 - 0.32 11.1 7.4 0.99 9.6 7.4 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Hva1_TUDOR PF11160.8 KXX74793.1 - 1.4e-13 50.8 1.8 1.7e-13 50.5 1.8 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain HNH PF01844.23 KXX74793.1 - 0.4 10.9 2.8 2.8 8.2 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease VID27 PF08553.10 KXX74794.1 - 3.9e-192 638.0 0.0 5.5e-192 637.5 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KXX74794.1 - 2.7e-77 258.5 0.2 2.7e-77 258.5 0.2 2.6 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KXX74794.1 - 6.3e-44 148.7 1.0 1.2e-43 147.8 0.5 1.8 2 0 0 2 2 2 1 VID27 PH-like domain DNA_pol_phi PF04931.13 KXX74794.1 - 1.1 7.3 10.8 1.7 6.6 10.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi PEP_hydrolase PF09370.10 KXX74795.1 - 3.3e-133 442.9 0.1 3.7e-133 442.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 KXX74795.1 - 0.0053 16.2 0.2 0.0087 15.5 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Radical_SAM PF04055.21 KXX74795.1 - 0.2 12.0 0.0 0.43 10.9 0.0 1.5 1 1 0 1 1 1 0 Radical SAM superfamily VSP PF03302.13 KXX74796.1 - 0.0077 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Myc_target_1 PF15179.6 KXX74796.1 - 0.044 13.7 0.1 0.089 12.7 0.1 1.5 2 0 0 2 2 2 0 Myc target protein 1 Cu_amine_oxid PF01179.20 KXX74798.1 - 0.082 11.8 0.4 0.1 11.5 0.4 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain HCV_capsid PF01543.17 KXX74798.1 - 0.92 9.7 0.0 0.92 9.7 0.0 2.8 1 1 2 3 3 3 0 Hepatitis C virus capsid protein UPF0261 PF06792.11 KXX74799.1 - 3.6e-147 490.5 0.0 1.3e-145 485.4 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0261) TPR_12 PF13424.6 KXX74801.1 - 9.2e-40 134.8 20.3 2.2e-12 47.1 0.1 6.5 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXX74801.1 - 1.5e-22 78.7 20.5 0.00012 21.8 0.1 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX74801.1 - 2e-13 50.4 17.0 4.8e-10 39.3 8.9 3.5 1 1 2 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 KXX74801.1 - 9.1e-08 31.7 8.3 0.21 11.9 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX74801.1 - 2e-07 31.4 17.6 0.69 10.5 1.2 6.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 KXX74801.1 - 1e-06 28.8 29.9 0.046 14.4 0.3 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX74801.1 - 4.8e-05 23.2 25.5 0.91 9.8 0.4 8.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX74801.1 - 0.00083 20.0 13.9 0.31 11.7 0.0 6.5 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXX74801.1 - 0.001 19.5 14.8 1.9 9.3 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat NACHT PF05729.12 KXX74801.1 - 0.0016 18.4 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX74801.1 - 0.0025 18.2 0.0 0.015 15.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX74801.1 - 0.0039 17.5 0.1 0.026 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain TPR_7 PF13176.6 KXX74801.1 - 0.011 15.7 13.0 0.3 11.2 0.1 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX74801.1 - 0.014 16.1 29.1 8 7.6 0.3 9.2 8 2 2 10 10 8 0 Tetratricopeptide repeat NB-ARC PF00931.22 KXX74801.1 - 0.039 13.1 0.0 0.27 10.4 0.0 2.3 1 1 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KXX74801.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_1 PF00515.28 KXX74801.1 - 1.8 8.5 18.4 5.7 6.9 0.1 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Ank_4 PF13637.6 KXX74802.1 - 6.8e-35 119.0 0.0 3.3e-08 33.9 0.0 5.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX74802.1 - 7.4e-33 113.0 0.0 1.3e-10 41.7 0.0 4.9 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXX74802.1 - 2.7e-27 94.0 0.0 4.8e-05 23.6 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXX74802.1 - 1.1e-21 76.6 0.0 1.3e-05 25.4 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX74802.1 - 9.6e-21 71.7 0.0 0.053 14.1 0.0 7.4 6 0 0 6 6 6 5 Ankyrin repeat NACHT PF05729.12 KXX74802.1 - 0.00014 21.8 0.0 0.00041 20.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXX74802.1 - 0.00018 21.8 0.0 0.0021 18.3 0.0 2.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KXX74802.1 - 0.00066 20.1 0.0 0.0086 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KXX74802.1 - 0.0059 17.2 0.1 0.022 15.4 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXX74802.1 - 0.017 14.7 0.0 0.076 12.5 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) KAP_NTPase PF07693.14 KXX74802.1 - 0.034 13.4 0.2 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 KXX74802.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX74802.1 - 0.055 13.9 0.0 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Hydrolase_4 PF12146.8 KXX74802.1 - 0.12 11.6 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TauD PF02668.16 KXX74803.1 - 1.8e-32 113.2 0.1 2.6e-32 112.7 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_M66 PF10462.9 KXX74803.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Amidase PF01425.21 KXX74804.1 - 2.1e-72 244.5 0.0 2.7e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Amidase HET PF06985.11 KXX74805.1 - 0.00012 22.5 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Esterase PF00756.20 KXX74806.1 - 0.00055 19.7 0.2 0.0053 16.4 0.2 2.0 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KXX74806.1 - 0.004 16.7 0.0 0.0094 15.5 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KXX74806.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KXX74806.1 - 0.061 12.9 0.3 4.1 6.9 0.1 2.2 1 1 1 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.16 KXX74807.1 - 4.7e-27 94.9 37.2 2.1e-15 56.5 28.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4407 PF14362.6 KXX74807.1 - 7.7 5.8 7.6 11 5.2 2.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) AflR PF08493.10 KXX74808.1 - 1.6e-12 47.5 1.4 2.3e-12 47.0 1.4 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Astacin PF01400.24 KXX74809.1 - 0.00062 19.4 0.7 0.053 13.1 0.5 3.4 4 0 0 4 4 4 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KXX74809.1 - 0.027 14.3 0.4 0.21 11.4 0.8 2.2 2 1 0 2 2 2 0 Matrixin Reprolysin_5 PF13688.6 KXX74809.1 - 0.035 14.3 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXX74809.1 - 0.045 13.4 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXX74809.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KXX74809.1 - 0.19 10.6 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 LysM PF01476.20 KXX74810.1 - 2.2e-20 72.4 0.1 0.0029 17.6 0.0 6.2 6 0 0 6 6 6 6 LysM domain HET PF06985.11 KXX74812.1 - 0.0004 20.8 0.0 0.001 19.5 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.22 KXX74813.1 - 7.6e-09 35.2 0.1 1e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Subtilase family Response_reg PF00072.24 KXX74813.1 - 0.057 13.6 0.0 0.25 11.5 0.0 1.8 1 1 1 2 2 2 0 Response regulator receiver domain Glyco_hydro_43 PF04616.14 KXX74814.1 - 8.4e-53 179.5 4.9 1e-52 179.2 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KXX74814.1 - 3.5e-40 137.2 0.8 6.1e-40 136.4 0.8 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 KXX74814.1 - 4.3e-08 33.3 0.5 8.1e-08 32.4 0.5 1.4 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KXX74814.1 - 0.003 17.2 0.7 0.0046 16.6 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF2252 PF10009.9 KXX74815.1 - 7.3e-120 400.6 0.5 8.8e-120 400.3 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.23 KXX74815.1 - 3.6e-05 23.8 0.4 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family zf_Hakai PF18408.1 KXX74815.1 - 0.067 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain Glyco_hydro_18 PF00704.28 KXX74816.1 - 7.2e-66 223.0 0.0 8.7e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KXX74816.1 - 1.1e-09 38.6 16.7 4.1e-09 36.8 8.0 2.6 2 0 0 2 2 2 2 Chitin recognition protein Fungal_lectin_2 PF18647.1 KXX74817.1 - 1.1e-39 134.9 0.6 1.1e-39 134.9 0.6 2.0 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 KXX74817.1 - 1.6e-14 54.7 0.1 9.1e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX74817.1 - 3.8e-07 30.3 0.0 1.2e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Abhydrolase_1 PF00561.20 KXX74818.1 - 3.8e-09 36.6 0.0 7.9e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX74818.1 - 4.3e-05 24.2 20.0 4.3e-05 24.2 20.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX74818.1 - 0.0033 16.7 0.0 0.034 13.4 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 KXX74818.1 - 0.26 10.3 0.0 0.34 9.9 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 SnoaL_4 PF13577.6 KXX74819.1 - 1.1e-44 151.6 3.5 3.6e-19 69.1 0.0 3.3 3 0 0 3 3 3 3 SnoaL-like domain bMG3 PF11974.8 KXX74819.1 - 0.03 14.4 0.1 0.066 13.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Big_3_5 PF16640.5 KXX74819.1 - 0.032 14.4 1.2 0.032 14.4 1.2 2.3 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) SnoaL_2 PF12680.7 KXX74819.1 - 0.043 14.4 2.2 2.5 8.8 0.0 3.7 4 1 0 4 4 4 0 SnoaL-like domain HBM PF16591.5 KXX74821.1 - 0.034 13.6 2.9 0.045 13.2 2.9 1.3 1 1 0 1 1 1 0 Helical bimodular sensor domain EzrA PF06160.12 KXX74821.1 - 0.037 12.2 0.4 0.048 11.8 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Abhydrolase_3 PF07859.13 KXX74822.1 - 2.1e-20 73.5 0.1 5.5e-20 72.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXX74822.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family MFS_1 PF07690.16 KXX74823.1 - 3.4e-36 124.9 57.0 3.1e-35 121.7 57.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily KGG PF10685.9 KXX74824.1 - 2.5e-27 94.3 14.4 1.8e-11 43.9 0.5 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif TPR_12 PF13424.6 KXX74825.1 - 9.6e-24 83.5 23.6 3.7e-10 40.0 2.7 3.6 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXX74825.1 - 2.9e-19 68.3 10.8 7.8e-06 25.6 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 KXX74825.1 - 2.5e-11 43.3 0.0 6.5e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_8 PF13181.6 KXX74825.1 - 8.2e-11 41.2 0.6 0.33 11.3 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXX74825.1 - 1.2e-08 35.0 2.8 0.85 10.6 0.1 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX74825.1 - 5.2e-08 32.4 3.3 0.089 12.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX74825.1 - 7.6e-08 32.5 0.9 0.086 13.1 0.6 4.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXX74825.1 - 4.6e-06 27.0 6.9 0.085 13.4 0.2 4.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX74825.1 - 6e-06 25.9 0.3 8.3 6.7 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX74825.1 - 7.7e-05 23.3 11.3 1.9 9.2 0.0 4.9 3 2 2 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXX74825.1 - 0.0013 19.0 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.14 KXX74825.1 - 0.0015 18.0 0.0 0.0074 15.8 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PPR_1 PF12854.7 KXX74825.1 - 0.0041 16.8 0.3 39 4.1 0.0 4.1 4 0 0 4 4 4 0 PPR repeat PPR PF01535.20 KXX74825.1 - 0.0079 16.4 0.4 89 3.7 0.0 4.3 4 0 0 4 4 4 0 PPR repeat TPR_20 PF14561.6 KXX74825.1 - 0.0093 16.3 10.2 2.8 8.3 0.3 4.5 2 1 2 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KXX74825.1 - 0.024 15.0 0.5 0.15 12.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain PGAP1 PF07819.13 KXX74825.1 - 0.042 13.6 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 PGAP1-like protein NACHT PF05729.12 KXX74825.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TPR_6 PF13174.6 KXX74825.1 - 0.1 13.3 0.3 73 4.3 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat WD40 PF00400.32 KXX74827.1 - 3.2e-11 43.6 6.1 0.042 14.7 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74827.1 - 0.012 15.9 0.1 1.7 9.0 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 KXX74828.1 - 2.4e-09 36.5 0.8 7.9e-09 34.8 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX74828.1 - 1.1e-05 25.5 10.2 1.1e-05 25.5 10.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.6 KXX74829.1 - 4.6e-15 56.2 0.0 1.5e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX74829.1 - 1.8e-07 31.7 0.0 3.6e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXX74829.1 - 0.0062 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Glyco_hydro_45 PF02015.16 KXX74829.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 UPF0086 PF01868.16 KXX74830.1 - 1.6e-31 108.1 0.2 2.2e-31 107.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.21 KXX74831.1 - 5.3e-18 64.9 0.0 1.4e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase SLX9 PF15341.6 KXX74831.1 - 5.8 7.3 6.0 11 6.4 4.1 2.2 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Pre-PUA PF17832.1 KXX74832.1 - 7e-22 77.9 0.3 1.1e-21 77.3 0.3 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KXX74832.1 - 6.5e-14 51.6 0.1 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 PUA domain DUF1772 PF08592.11 KXX74833.1 - 4.7e-06 26.9 9.8 7e-05 23.2 9.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Pkinase PF00069.25 KXX74834.1 - 2.2e-26 92.8 0.0 3.3e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74834.1 - 9.6e-09 34.9 0.1 0.00081 18.7 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXX74834.1 - 0.019 14.3 0.0 0.04 13.3 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX74834.1 - 0.092 12.6 0.5 0.22 11.4 0.1 1.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pantoate_ligase PF02569.15 KXX74835.1 - 1.2e-91 306.6 0.0 1.4e-91 306.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase NST1 PF13945.6 KXX74836.1 - 6.7e-55 186.2 6.3 6.7e-55 186.2 6.3 4.5 2 2 2 4 4 4 1 Salt tolerance down-regulator Ras PF00071.22 KXX74837.1 - 2.4e-46 157.3 0.0 2.7e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX74837.1 - 1.1e-19 70.8 0.0 1.7e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX74837.1 - 4.1e-06 26.4 0.0 5.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXX74837.1 - 0.029 13.8 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 KXX74837.1 - 0.089 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 KXX74837.1 - 0.15 11.8 0.0 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MRP-L28 PF09812.9 KXX74838.1 - 3.7e-07 30.4 0.1 4.2e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Inhibitor_I78 PF11720.8 KXX74839.1 - 2e-09 37.3 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KXX74839.1 - 0.0022 18.7 0.1 0.0031 18.2 0.1 1.2 1 0 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.8 KXX74839.1 - 0.057 13.8 0.0 0.072 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) adh_short PF00106.25 KXX74840.1 - 2.6e-12 46.6 0.1 2.6e-07 30.3 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX74840.1 - 9.2e-06 25.4 0.2 0.032 13.8 0.0 3.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF2039 PF10217.9 KXX74840.1 - 0.0088 16.4 0.3 0.017 15.4 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) FAA_hydro_N_2 PF18288.1 KXX74840.1 - 0.054 13.9 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Ofd1_CTDD PF10637.9 KXX74840.1 - 0.073 12.4 1.5 2.4 7.4 0.0 2.7 2 1 0 3 3 3 0 Oxoglutarate and iron-dependent oxygenase degradation C-term F-box PF00646.33 KXX74841.1 - 0.034 14.0 0.2 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 F-box domain SUIM_assoc PF16619.5 KXX74842.1 - 0.024 14.7 2.7 0.066 13.3 2.7 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LapA_dom PF06305.11 KXX74842.1 - 0.055 13.3 0.1 0.055 13.3 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4690 PF15756.5 KXX74842.1 - 0.098 13.3 0.5 0.45 11.1 0.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Tweety PF04906.13 KXX74842.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Tweety TRP PF06011.12 KXX74842.1 - 0.25 10.0 0.1 0.36 9.5 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.6 KXX74842.1 - 0.45 11.4 4.3 1.8 9.5 4.3 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Spt20 PF12090.8 KXX74842.1 - 4 7.0 6.7 6.1 6.4 6.7 1.2 1 0 0 1 1 1 0 Spt20 family AA_permease_2 PF13520.6 KXX74843.1 - 1e-76 258.5 28.3 1.2e-76 258.2 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX74843.1 - 1.2e-14 53.8 28.3 3.3e-14 52.4 28.3 1.7 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KXX74843.1 - 0.00083 18.2 5.8 0.00083 18.2 5.8 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein AMP-binding PF00501.28 KXX74844.1 - 7.5e-43 146.7 0.0 4.4e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXX74844.1 - 7.3e-07 30.1 0.0 1.6e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lactamase_B_2 PF12706.7 KXX74845.1 - 3.1e-13 49.7 0.3 1.2e-11 44.5 0.3 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXX74845.1 - 7.4e-09 35.7 1.8 1e-07 32.0 1.2 2.5 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXX74845.1 - 0.015 15.3 2.6 0.12 12.4 0.6 2.5 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily K_channel_TID PF07941.11 KXX74845.1 - 1.3 9.5 4.5 2.5 8.6 4.5 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_hydro_61 PF03443.14 KXX74846.1 - 1.4e-53 181.9 0.0 1.8e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ldh_1_C PF02866.18 KXX74847.1 - 5.4e-47 159.8 0.0 1.1e-46 158.9 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXX74847.1 - 1.1e-44 151.9 0.0 2.5e-44 150.8 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXX74847.1 - 1.9e-05 23.8 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KXX74847.1 - 0.19 11.3 0.1 0.74 9.3 0.1 1.9 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 KXX74847.1 - 0.19 12.2 0.5 0.62 10.5 0.1 2.1 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain V-SNARE_C PF12352.8 KXX74848.1 - 2.4e-14 53.3 0.5 2.4e-14 53.3 0.5 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXX74848.1 - 8e-05 22.5 0.0 0.00026 20.9 0.0 1.8 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 KXX74848.1 - 0.0053 16.2 0.1 0.0086 15.5 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Sigma70_r4 PF04545.16 KXX74848.1 - 0.0061 16.1 0.2 0.014 14.9 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 KxDL PF10241.9 KXX74848.1 - 0.014 15.6 1.0 4.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein JAKMIP_CC3 PF16034.5 KXX74848.1 - 0.044 13.7 0.0 0.083 12.8 0.0 1.4 1 1 0 1 1 1 0 JAKMIP CC3 domain Mito_fiss_reg PF05308.11 KXX74848.1 - 0.092 12.8 1.0 0.14 12.2 0.9 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator HTH_DeoR PF08220.12 KXX74848.1 - 0.11 12.2 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain TPR_MLP1_2 PF07926.12 KXX74848.1 - 0.13 12.3 5.8 0.36 10.9 1.6 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 KXX74848.1 - 0.15 11.8 3.4 0.47 10.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Allexi_40kDa PF05549.11 KXX74848.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DivIC PF04977.15 KXX74848.1 - 0.18 11.6 2.6 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF2721 PF11026.8 KXX74848.1 - 1.2 9.1 3.3 9.6 6.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) TPK_B1_binding PF04265.14 KXX74849.1 - 7e-26 89.7 0.0 1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.16 KXX74849.1 - 1.8e-22 79.6 0.0 3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Gemini_mov PF01708.16 KXX74850.1 - 0.072 12.9 1.4 0.13 12.0 1.4 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein Whi5 PF08528.11 KXX74851.1 - 1.7e-11 43.5 0.0 3.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Whi5 like WD40 PF00400.32 KXX74852.1 - 2.5e-36 123.1 20.0 4.8e-09 36.7 0.6 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.12 KXX74852.1 - 3.9e-23 82.2 0.1 7.3e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KXX74852.1 - 1.1e-18 67.3 5.5 1.4e-05 25.3 0.8 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX74852.1 - 2.5e-06 26.7 2.2 0.37 9.7 0.6 3.8 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXX74852.1 - 3.6e-06 25.9 4.8 0.92 8.1 0.4 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.12 KXX74852.1 - 0.0014 18.5 1.0 40 4.3 0.1 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KXX74852.1 - 0.0028 18.1 0.0 0.0067 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KXX74852.1 - 0.026 14.8 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX74852.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 KXX74852.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit bPH_4 PF06713.11 KXX74852.1 - 0.19 11.9 0.1 21 5.3 0.0 3.4 3 1 1 4 4 4 0 Bacterial PH domain E1-E2_ATPase PF00122.20 KXX74853.1 - 1.5e-18 67.0 0.0 3.7e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXX74853.1 - 6e-15 56.1 2.8 1.1e-08 35.6 3.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXX74853.1 - 0.0024 17.7 1.2 0.038 13.7 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXX74853.1 - 0.003 17.6 2.4 0.0035 17.4 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) S6PP PF05116.13 KXX74853.1 - 0.028 14.0 0.4 1.9 8.0 0.0 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase TRAP-gamma PF07074.12 KXX74853.1 - 0.18 11.3 3.8 0.51 9.9 3.8 1.8 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4059 PF13268.6 KXX74853.1 - 0.8 10.2 5.2 9.6 6.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) SNF2_N PF00176.23 KXX74858.1 - 1.5e-66 224.6 0.3 2.5e-66 223.8 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX74858.1 - 5.1e-18 65.5 0.0 2.6e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX74858.1 - 7.1e-10 39.1 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXX74858.1 - 0.017 14.3 0.1 1.4 8.0 0.0 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 HSA PF07529.13 KXX74858.1 - 0.055 13.8 13.1 0.46 10.8 12.7 2.7 1 1 0 1 1 1 0 HSA PI3K_1B_p101 PF10486.9 KXX74858.1 - 4 5.1 7.2 6.4 4.4 7.2 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit p450 PF00067.22 KXX74860.1 - 4.3e-30 104.9 0.1 6e-29 101.1 0.1 2.3 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 KXX74861.1 - 2.9e-13 50.9 2.8 4.3e-13 50.4 2.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX74861.1 - 7.7e-06 25.3 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX74861.1 - 0.0024 17.5 0.2 0.0064 16.2 0.1 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2789 PF10982.8 KXX74861.1 - 0.086 13.0 0.1 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) GMC_oxred_N PF00732.19 KXX74862.1 - 4.9e-31 108.2 0.0 2.4e-29 102.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX74862.1 - 5e-30 104.9 0.1 1.5e-29 103.4 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXX74862.1 - 0.00058 19.2 0.0 0.00098 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX74862.1 - 0.0039 16.3 0.0 0.03 13.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXX74862.1 - 0.024 14.8 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX74862.1 - 0.07 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXX74862.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase peroxidase PF00141.23 KXX74863.1 - 7.8e-85 284.2 0.0 1.1e-45 156.2 0.0 2.4 2 0 0 2 2 2 2 Peroxidase EthD PF07110.11 KXX74863.1 - 0.19 12.9 1.1 0.34 12.1 0.3 1.8 2 0 0 2 2 2 0 EthD domain Acetyltransf_10 PF13673.7 KXX74865.1 - 1.6e-05 24.8 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX74865.1 - 8.4e-05 22.8 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX74865.1 - 0.0004 20.7 0.0 0.00067 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NDUF_B8 PF05821.11 KXX74866.1 - 5.2e-06 26.4 3.0 8.7e-06 25.7 3.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Mid2 PF04478.12 KXX74868.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3180 PF11377.8 KXX74868.1 - 0.037 14.2 1.0 0.083 13.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Conotoxin PF02950.17 KXX74868.1 - 0.058 14.4 0.0 0.12 13.4 0.0 1.5 1 0 0 1 1 1 0 Conotoxin Phage_holin_2_4 PF16082.5 KXX74868.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like PhoR PF11808.8 KXX74868.1 - 0.14 12.6 0.2 0.42 11.0 0.0 1.8 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR MtrF PF09472.10 KXX74868.1 - 0.15 11.5 2.4 0.36 10.3 2.4 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Adeno_E3_CR2 PF02439.15 KXX74868.1 - 0.36 10.6 3.1 0.62 9.9 3.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 KXX74869.1 - 1.7e-62 211.2 0.0 2.5e-38 132.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74869.1 - 2.9e-27 95.6 0.0 6.4e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KXX74869.1 - 6.5e-14 52.1 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KXX74869.1 - 1.5e-07 31.1 0.0 7.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXX74869.1 - 5.1e-05 23.3 0.1 0.0037 17.2 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family PAS_9 PF13426.7 KXX74869.1 - 0.0015 18.8 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 KXX74869.1 - 0.013 14.4 0.7 0.019 13.9 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KXX74869.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXX74869.1 - 0.033 13.8 0.0 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAS PF00989.25 KXX74869.1 - 0.065 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 KXX74869.1 - 0.16 11.0 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sugar_tr PF00083.24 KXX74870.1 - 2.1e-24 86.2 23.0 2e-13 50.0 9.8 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter Zn_clus PF00172.18 KXX74871.1 - 9.5e-09 35.2 13.9 9.5e-09 35.2 13.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX74871.1 - 2.9e-05 23.2 0.2 0.00032 19.8 0.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Helo_like_N PF17111.5 KXX74872.1 - 0.082 12.3 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins bZIP_1 PF00170.21 KXX74873.1 - 7.2e-05 22.8 9.7 0.00014 21.9 9.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF5082 PF16888.5 KXX74873.1 - 0.045 14.0 0.4 0.073 13.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) bZIP_2 PF07716.15 KXX74873.1 - 1.2 9.3 11.6 5.8 7.1 11.6 2.0 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KXX74873.1 - 2.2 8.9 8.0 4.3 7.9 8.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor eIF-3_zeta PF05091.12 KXX74874.1 - 8.7e-207 688.2 0.0 1.1e-206 687.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KXX74874.1 - 0.0082 15.8 0.1 0.021 14.5 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF569) CBFB_NFYA PF02045.15 KXX74875.1 - 4e-28 97.8 4.6 9.9e-28 96.5 4.6 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B UBA2_C PF16195.5 KXX74875.1 - 0.0052 17.4 6.2 0.018 15.7 6.2 2.0 1 0 0 1 1 1 1 SUMO-activating enzyme subunit 2 C-terminus DUF4604 PF15377.6 KXX74875.1 - 1.6 9.2 12.8 0.43 11.0 9.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) LSM PF01423.22 KXX74876.1 - 2.1e-16 59.4 0.0 3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXX74876.1 - 0.0032 17.6 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 KXX74876.1 - 0.042 13.5 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Hfq protein DUF150_C PF17384.2 KXX74876.1 - 0.065 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DRMBL PF07522.14 KXX74877.1 - 1.8e-30 105.3 0.0 3.4e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KXX74877.1 - 7.3e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DGF-1_C PF11040.8 KXX74877.1 - 5.8 7.0 12.8 0.64 10.1 0.1 4.1 4 0 0 4 4 4 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Methyltransf_25 PF13649.6 KXX74878.1 - 1.4e-14 54.6 0.0 2.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX74878.1 - 7.5e-12 45.9 0.0 1.1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74878.1 - 6.3e-11 42.8 0.0 9.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74878.1 - 4e-08 33.2 0.0 5.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX74878.1 - 2.8e-07 30.1 0.0 4.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXX74878.1 - 3.5e-06 26.9 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX74878.1 - 0.00019 21.0 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KXX74878.1 - 0.0059 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 KXX74878.1 - 0.0093 15.4 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KXX74878.1 - 0.23 11.0 0.0 0.33 10.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Hydrophobin PF01185.18 KXX74879.1 - 0.00039 21.0 4.6 0.00039 21.0 4.6 2.1 1 1 1 2 2 2 1 Fungal hydrophobin Ferric_reduct PF01794.19 KXX74881.1 - 0.0002 21.4 2.0 0.00033 20.8 2.0 1.3 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Herpes_ORF11 PF04797.13 KXX74881.1 - 0.064 12.0 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein Trp_DMAT PF11991.8 KXX74882.1 - 3.5e-93 312.9 0.0 4.5e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase TetR_C_33 PF13305.6 KXX74882.1 - 0.13 13.0 1.1 0.71 10.6 0.1 2.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF4938 PF16292.5 KXX74883.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4938) Acetyltransf_1 PF00583.25 KXX74884.1 - 0.061 13.6 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CysG_dimeriser PF10414.9 KXX74884.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Kelch_6 PF13964.6 KXX74885.1 - 6.8e-29 99.2 13.3 2.3e-08 34.0 0.0 7.5 4 2 3 7 7 7 6 Kelch motif Kelch_1 PF01344.25 KXX74885.1 - 5e-28 96.4 15.8 8.4e-09 34.9 0.8 7.3 6 2 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KXX74885.1 - 2.6e-19 69.0 18.6 1.7e-06 27.9 0.0 7.5 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KXX74885.1 - 5.5e-18 64.8 10.1 9.2e-05 22.6 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KXX74885.1 - 3.8e-16 58.3 5.3 1.1e-05 25.1 0.0 7.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KXX74885.1 - 5.9e-14 51.7 2.8 0.0015 18.4 0.0 5.6 6 0 0 6 6 6 3 Kelch motif TRAM_2 PF18693.1 KXX74885.1 - 0.00056 20.0 0.2 0.0075 16.4 0.0 2.3 2 0 0 2 2 2 1 TRAM domain DUF1668 PF07893.13 KXX74885.1 - 0.12 11.7 0.5 0.82 9.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1668) PQQ_3 PF13570.6 KXX74885.1 - 0.56 10.8 14.0 3.7 8.2 0.2 5.0 5 0 0 5 5 5 0 PQQ-like domain GTP_EFTU PF00009.27 KXX74886.1 - 0.007 15.9 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Ank_2 PF12796.7 KXX74887.1 - 6.4e-56 186.9 0.0 1.7e-15 57.3 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX74887.1 - 1.7e-35 120.6 4.8 2.6e-07 30.8 0.0 8.3 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX74887.1 - 7.2e-33 108.9 0.0 0.00046 20.4 0.0 10.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 KXX74887.1 - 1.1e-32 112.0 0.3 1.9e-06 28.3 0.1 7.0 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXX74887.1 - 1.5e-27 94.8 0.6 0.0022 18.4 0.0 9.6 9 0 0 9 9 9 6 Ankyrin repeat NACHT PF05729.12 KXX74887.1 - 8.3e-08 32.3 0.0 2.1e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX74887.1 - 4.1e-06 27.3 0.0 1.2e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX74887.1 - 0.00022 21.5 0.0 0.00065 20.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXX74887.1 - 0.0016 18.8 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KXX74887.1 - 0.014 16.0 0.0 0.03 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXX74887.1 - 0.024 14.8 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXX74887.1 - 0.046 13.7 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KXX74887.1 - 0.061 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KXX74887.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 KXX74887.1 - 0.12 12.0 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoD PF09423.10 KXX74889.1 - 4.7e-116 387.6 1.3 5.6e-116 387.4 1.3 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KXX74889.1 - 2.4e-33 114.5 0.0 4.9e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KXX74889.1 - 2.8e-05 24.6 0.2 6.3e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KXX74889.1 - 0.25 11.8 1.3 5.8 7.4 0.1 2.5 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase Glyco_hydro_7 PF00840.20 KXX74890.1 - 2.7e-202 672.2 8.9 3.1e-202 672.1 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 BioW PF03744.13 KXX74890.1 - 0.22 11.1 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase Telomerase_RBD PF12009.8 KXX74891.1 - 8.8e-52 174.8 0.5 2.7e-51 173.2 0.4 1.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KXX74891.1 - 1.8e-12 47.3 0.0 6.6e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Topo_Zn_Ribbon PF08272.11 KXX74891.1 - 0.057 13.1 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF4419 PF14388.6 KXX74892.1 - 1.7e-78 264.1 0.0 1.6e-77 260.9 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4419) LysR_substrate PF03466.20 KXX74892.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 LysR substrate binding domain RhoGEF PF00621.20 KXX74893.1 - 1.2e-29 103.9 1.1 1.6e-29 103.5 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 KXX74893.1 - 5.1e-08 32.8 2.7 2e-07 30.9 2.3 2.2 1 1 1 2 2 2 1 BAR domain MT-A70 PF05063.14 KXX74893.1 - 0.17 11.8 0.2 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 MT-A70 Spc7 PF08317.11 KXX74895.1 - 0.23 10.3 16.3 0.79 8.5 16.3 1.9 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 KXX74895.1 - 0.92 9.0 18.8 0.059 12.9 12.6 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 YflT PF11181.8 KXX74895.1 - 1.8 9.1 5.0 4.9 7.7 5.0 1.7 1 0 0 1 1 1 0 Heat induced stress protein YflT PKcGMP_CC PF16808.5 KXX74895.1 - 2 8.3 10.4 14 5.6 0.2 4.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Uds1 PF15456.6 KXX74895.1 - 2.5 8.3 19.2 8.5 6.6 15.8 3.8 2 0 0 2 2 2 0 Up-regulated During Septation SWIB PF02201.18 KXX74896.1 - 1.2e-31 108.4 0.5 2.6e-31 107.3 0.5 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KXX74896.1 - 6.2e-16 58.1 1.5 1.2e-15 57.2 1.5 1.5 1 0 0 1 1 1 1 DEK C terminal domain FXMRP1_C_core PF12235.8 KXX74896.1 - 0.14 12.9 6.3 0.26 12.0 6.3 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DTHCT PF08070.11 KXX74896.1 - 0.14 12.9 21.9 0.087 13.6 3.7 2.5 1 1 1 2 2 2 0 DTHCT (NUC029) region zf-C3HC4_3 PF13920.6 KXX74897.1 - 9.9e-08 31.7 9.5 9.9e-08 31.7 9.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX74897.1 - 0.0011 18.7 12.4 0.0011 18.7 12.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX74897.1 - 0.01 16.1 12.9 0.01 16.1 12.9 2.9 3 0 0 3 3 3 0 Ring finger domain Cpn60_TCP1 PF00118.24 KXX74898.1 - 1.2e-143 479.3 12.9 1.4e-143 479.1 12.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 KXX74898.1 - 0.022 15.0 0.1 0.057 13.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 KXX74898.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Pyr_redox_2 PF07992.14 KXX74901.1 - 2.6e-12 46.6 0.3 9.2e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX74901.1 - 3.6e-12 46.2 0.4 5.4e-11 42.3 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX74901.1 - 1.6e-10 41.1 0.3 3.2e-05 23.7 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX74901.1 - 2.4e-08 33.5 0.5 2.4e-08 33.5 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXX74901.1 - 4e-08 32.4 0.2 1.4e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KXX74901.1 - 2.5e-07 30.8 0.3 4.3e-06 26.9 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXX74901.1 - 1.7e-06 27.6 0.4 3.1e-06 26.8 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX74901.1 - 5.6e-06 26.8 0.1 0.0033 17.9 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX74901.1 - 1.3e-05 24.4 0.3 2.8e-05 23.4 0.3 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KXX74901.1 - 3.8e-05 22.9 0.1 5.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXX74901.1 - 0.00043 19.7 0.1 0.24 10.6 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KXX74901.1 - 0.00057 18.9 3.5 0.2 10.5 0.3 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXX74901.1 - 0.0012 18.1 0.0 0.0041 16.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX74901.1 - 0.0032 16.7 0.1 0.0054 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KXX74901.1 - 0.0036 16.6 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXX74901.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KXX74901.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyl-CoA_dh_1 PF00441.24 KXX74902.1 - 1.7e-30 106.2 2.2 5.3e-30 104.6 0.8 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXX74902.1 - 1.8e-22 79.3 0.1 2.8e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXX74902.1 - 2.4e-13 50.7 1.4 5.4e-13 49.6 0.2 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXX74902.1 - 0.00072 19.8 1.0 0.0037 17.6 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Defensin_2 PF01097.18 KXX74903.1 - 8.1e-05 22.5 5.6 8.1e-05 22.5 5.6 2.0 2 0 0 2 2 2 1 Arthropod defensin SprB PF13573.6 KXX74903.1 - 0.13 12.0 0.6 0.13 12.0 0.6 2.0 2 0 0 2 2 2 0 SprB repeat HET PF06985.11 KXX74904.1 - 1.7e-28 99.8 0.0 3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GSAP-16 PF14959.6 KXX74904.1 - 0.22 11.4 0.0 0.49 10.3 0.0 1.5 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Ribonuc_2-5A PF06479.12 KXX74905.1 - 1.1e-44 151.6 0.0 1.9e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KXX74905.1 - 5.7e-38 130.8 0.0 2.4e-24 86.1 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74905.1 - 3.5e-16 59.3 0.0 3.7e-13 49.3 0.0 3.0 3 0 0 3 3 3 1 Protein tyrosine kinase PQQ PF01011.21 KXX74905.1 - 2.7e-07 30.2 1.0 0.00095 19.0 0.0 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.14 KXX74905.1 - 5.1e-05 22.7 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 KXX74905.1 - 0.00021 21.0 0.3 0.0058 16.2 0.2 2.1 1 1 1 2 2 2 2 PQQ-like domain Pkinase_fungal PF17667.1 KXX74905.1 - 0.0017 17.2 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXX74905.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Helo_like_N PF17111.5 KXX74907.1 - 1.9e-08 33.9 0.1 2.2e-08 33.7 0.1 1.0 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXX74907.1 - 0.00051 20.2 0.0 0.00063 19.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CENP-Q PF13094.6 KXX74907.1 - 0.087 13.0 0.4 0.11 12.6 0.4 1.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit N_NLPC_P60 PF12912.7 KXX74907.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.7 1 1 0 1 1 1 0 NLPC_P60 stabilising domain, N term YL1 PF05764.13 KXX74908.1 - 9.6 6.2 11.3 15 5.6 11.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein eIF2A PF08662.11 KXX74909.1 - 2.6e-37 128.6 4.1 1.7e-35 122.6 0.4 3.9 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KXX74909.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.28 KXX74910.1 - 3.3e-14 53.1 0.6 0.00015 22.1 0.0 4.0 4 0 0 4 4 4 3 CBS domain Importin_rep_4 PF18808.1 KXX74911.1 - 1.2e-32 112.0 7.3 2.6e-31 107.8 1.1 4.8 4 1 1 5 5 4 1 Importin repeat Importin_rep_5 PF18816.1 KXX74911.1 - 4.9e-20 71.6 1.2 4.9e-20 71.6 1.2 3.2 3 0 0 3 3 2 1 Importin repeat HEAT_2 PF13646.6 KXX74911.1 - 9.7e-18 64.4 19.2 6.6e-07 29.6 0.6 9.1 6 3 5 11 11 11 6 HEAT repeats HEAT PF02985.22 KXX74911.1 - 1.5e-17 62.2 18.2 0.0044 17.1 0.0 12.0 14 0 0 14 14 12 3 HEAT repeat HEAT_EZ PF13513.6 KXX74911.1 - 1.3e-16 60.7 25.6 8.2e-11 42.2 0.2 9.8 9 1 2 11 11 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KXX74911.1 - 8.1e-13 48.8 0.2 0.0043 17.6 0.1 7.3 3 2 4 7 7 7 2 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 KXX74911.1 - 6e-12 45.7 0.5 1.4e-10 41.3 0.2 3.2 2 0 0 2 2 2 1 Importin repeat 6 RIX1 PF08167.12 KXX74911.1 - 2.2e-09 37.3 0.0 0.00017 21.4 0.0 4.9 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis DRIM PF07539.12 KXX74911.1 - 4.8e-09 35.1 2.6 0.0027 16.1 0.1 4.2 3 2 1 4 4 4 3 Down-regulated in metastasis DUF3385 PF11865.8 KXX74911.1 - 2.4e-08 34.0 0.1 0.0075 16.2 0.1 6.1 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KXX74911.1 - 5e-07 29.9 1.3 0.28 11.2 0.0 5.6 4 3 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KXX74911.1 - 1.3e-06 27.9 7.0 5.1e-06 25.9 0.3 3.7 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KXX74911.1 - 1.6e-06 27.8 1.0 0.0053 16.3 0.1 5.1 6 2 1 7 7 7 1 CLASP N terminal Adaptin_N PF01602.20 KXX74911.1 - 7.8e-06 24.7 1.0 0.016 13.8 0.1 4.7 4 1 0 5 5 5 1 Adaptin N terminal region Xpo1 PF08389.12 KXX74911.1 - 4e-05 23.7 0.1 0.0023 18.0 0.0 3.4 2 1 0 2 2 2 1 Exportin 1-like protein MMS19_N PF14500.6 KXX74911.1 - 0.00017 21.2 2.3 1.9 8.0 0.2 4.6 5 0 0 5 5 4 2 Dos2-interacting transcription regulator of RNA-Pol-II DUF3535 PF12054.8 KXX74911.1 - 0.00029 20.2 0.5 0.0024 17.2 0.1 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3535) DUF4042 PF13251.6 KXX74911.1 - 0.0024 17.6 0.1 3.9 7.1 0.0 4.2 4 0 0 4 4 3 1 Domain of unknown function (DUF4042) IBN_N PF03810.19 KXX74911.1 - 0.0033 17.3 3.3 0.02 14.8 0.1 3.9 4 1 0 4 4 3 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KXX74911.1 - 0.0039 17.3 3.7 0.16 12.2 0.4 4.6 6 1 0 6 6 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Dopey_N PF04118.14 KXX74911.1 - 0.0045 16.1 1.7 1 8.4 0.0 3.5 3 1 1 4 4 4 1 Dopey, N-terminal V-ATPase_H_N PF03224.14 KXX74911.1 - 0.006 15.9 6.1 0.58 9.4 0.1 3.3 2 1 0 2 2 2 1 V-ATPase subunit H CAS_CSE1 PF03378.15 KXX74911.1 - 0.02 13.4 0.5 5.1 5.5 0.0 3.4 4 0 0 4 4 4 0 CAS/CSE protein, C-terminus Arm PF00514.23 KXX74911.1 - 0.053 13.6 12.6 0.62 10.2 0.1 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 KXX74911.1 - 0.064 12.8 0.0 4.8 6.6 0.0 3.8 2 1 1 3 3 3 0 Tti2 family DNA_alkylation PF08713.11 KXX74911.1 - 0.075 12.7 0.1 0.48 10.1 0.0 2.5 2 0 0 2 2 2 0 DNA alkylation repair enzyme Cnd3 PF12719.7 KXX74911.1 - 0.089 12.0 0.3 1.8 7.7 0.0 3.3 4 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain ParcG PF10274.9 KXX74911.1 - 0.091 12.9 0.3 5.7 7.0 0.3 2.9 1 1 1 2 2 2 0 Parkin co-regulated protein TFCD_C PF12612.8 KXX74911.1 - 0.13 12.1 0.1 3.1 7.6 0.0 3.2 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal Rsa3 PF14615.6 KXX74912.1 - 3e-21 74.7 0.4 3.8e-21 74.4 0.4 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 RTA1 PF04479.13 KXX74913.1 - 2.4e-44 151.5 6.9 4.3e-44 150.6 6.9 1.4 1 0 0 1 1 1 1 RTA1 like protein DUF4386 PF14329.6 KXX74913.1 - 0.0093 15.9 2.4 0.0093 15.9 2.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4386) ATP1G1_PLM_MAT8 PF02038.16 KXX74913.1 - 1.5 8.3 4.0 0.4 10.1 0.3 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Peptidase_C14 PF00656.22 KXX74915.1 - 1.3e-64 218.5 0.0 1.6e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Extensin_2 PF04554.13 KXX74916.1 - 0.31 11.1 37.3 0.54 10.4 37.3 1.5 1 1 0 1 1 1 0 Extensin-like region EI24 PF07264.11 KXX74918.1 - 9.6e-16 58.5 4.8 2.7e-13 50.6 4.8 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 KXX74919.1 - 2.1e-43 147.6 0.0 4.9e-43 146.4 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 SKG6 PF08693.10 KXX74920.1 - 0.00056 19.3 2.9 0.00056 19.3 2.9 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain FmdA_AmdA PF03069.15 KXX74922.1 - 1.9e-131 438.4 0.0 2.2e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family OPA3 PF07047.12 KXX74923.1 - 4.3e-46 155.7 1.5 4.3e-46 155.7 1.5 1.3 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) VSG_B PF13206.6 KXX74923.1 - 0.013 14.8 1.7 0.018 14.3 1.7 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DnaJ PF00226.31 KXX74923.1 - 0.04 14.0 3.5 0.12 12.5 0.1 2.6 2 1 0 2 2 2 0 DnaJ domain DUF2681 PF10883.8 KXX74923.1 - 0.075 13.4 1.5 0.61 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3318 PF11780.8 KXX74923.1 - 0.076 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) BRI3BP PF14965.6 KXX74923.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 PAP_PilO PF06864.12 KXX74923.1 - 0.24 10.2 2.3 0.63 8.8 0.2 2.4 1 1 1 2 2 2 0 Pilin accessory protein (PilO) HAUS6_N PF14661.6 KXX74923.1 - 0.25 10.9 6.8 0.37 10.3 0.6 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF3563 PF12086.8 KXX74923.1 - 1.1 9.1 5.9 0.61 9.9 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) Tho2 PF11262.8 KXX74923.1 - 6.8 5.8 7.4 0.63 9.2 0.8 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 MFS_1 PF07690.16 KXX74924.1 - 1.7e-38 132.5 23.4 1.7e-38 132.5 23.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX74924.1 - 4.2e-14 52.3 9.7 4.2e-14 52.3 9.7 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.18 KXX74925.1 - 7.7e-14 51.4 1.0 1.4e-13 50.5 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX74925.1 - 2.2e-06 27.7 3.3 2.2e-06 27.7 3.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXX74925.1 - 0.044 14.3 0.1 0.044 14.3 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type HET PF06985.11 KXX74926.1 - 1.2e-11 45.2 7.6 4.8e-09 36.7 1.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RRM_1 PF00076.22 KXX74927.1 - 3.5e-09 36.3 0.0 1e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXX74927.1 - 1.7e-06 27.6 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KXX74927.1 - 0.01 15.6 0.1 0.03 14.1 0.0 1.8 1 1 1 2 2 2 0 Calcipressin Limkain-b1 PF11608.8 KXX74927.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 KXX74927.1 - 0.035 14.0 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 KXX74928.1 - 5.7e-61 206.2 0.0 8.2e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74928.1 - 3.1e-37 128.3 0.0 4.6e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX74928.1 - 4.4e-07 29.5 0.0 6.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.18 KXX74928.1 - 6.7e-07 29.4 0.1 0.00059 20.0 0.0 3.0 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.14 KXX74928.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXX74928.1 - 0.041 12.6 0.0 0.041 12.6 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KXX74928.1 - 0.082 11.8 0.0 0.28 10.1 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Sushi_2 PF09014.10 KXX74928.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AA_permease PF00324.21 KXX74929.1 - 5.1e-137 457.3 36.6 2.3e-135 451.9 32.6 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KXX74929.1 - 2.3e-35 122.3 35.1 3e-35 121.9 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KXX74929.1 - 0.14 10.9 0.9 0.31 9.8 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Glyco_hydro_47 PF01532.20 KXX74930.1 - 2e-169 564.3 0.0 2.6e-169 564.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3716 PF12511.8 KXX74932.1 - 7.3e-13 48.4 5.7 1.1e-12 47.8 5.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) RecO_C PF02565.15 KXX74932.1 - 0.12 12.2 0.7 0.25 11.1 0.7 1.7 1 1 0 1 1 1 0 Recombination protein O C terminal RICH PF05062.12 KXX74932.1 - 4.6 7.7 5.1 2.1e+02 2.4 0.0 3.1 2 1 0 2 2 2 0 RICH domain Autophagy_act_C PF03987.15 KXX74933.1 - 3.4e-13 50.0 0.1 5.6e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain WD40 PF00400.32 KXX74934.1 - 3.3e-14 53.0 5.2 0.0078 17.0 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74934.1 - 7.9e-06 26.1 0.0 0.08 13.2 0.0 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXX74934.1 - 0.0026 17.7 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat PPAK PF02818.15 KXX74936.1 - 1.5 9.1 7.7 0.16 12.2 2.0 2.4 2 0 0 2 2 2 0 PPAK motif Vps8 PF12816.7 KXX74938.1 - 9.9e-75 250.4 0.0 1.9e-74 249.5 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KXX74938.1 - 1e-05 25.4 0.1 0.0032 17.4 0.0 3.0 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 KXX74938.1 - 0.0016 18.4 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXX74938.1 - 0.0068 16.4 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXX74938.1 - 0.013 15.8 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KXX74938.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain CENP-B_dimeris PF09026.10 KXX74938.1 - 0.09 13.2 0.9 0.26 11.7 0.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Zn_ribbon_17 PF17120.5 KXX74938.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXX74938.1 - 0.28 11.0 2.2 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 RING-like zinc finger DUF3752 PF12572.8 KXX74939.1 - 4.5e-50 170.1 5.0 9.1e-50 169.1 5.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.6 KXX74940.1 - 7.7e-12 45.4 6.6 1.2e-11 44.7 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX74940.1 - 1e-07 31.7 6.7 1.6e-07 31.0 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXX74940.1 - 1.4e-07 31.1 0.9 2.4e-07 30.4 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXX74940.1 - 2.1e-07 30.7 4.0 3.4e-07 30.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX74940.1 - 6.9e-07 29.5 7.9 2.5e-06 27.7 7.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXX74940.1 - 6.3e-06 26.1 3.7 9.8e-06 25.4 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXX74940.1 - 0.0014 18.6 1.0 0.0014 18.6 1.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXX74940.1 - 0.0016 18.4 2.8 0.0034 17.4 2.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXX74940.1 - 0.0026 17.6 2.5 0.0039 17.0 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXX74940.1 - 0.013 15.3 6.5 0.021 14.6 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXX74940.1 - 0.094 12.9 3.2 0.23 11.7 3.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KXX74940.1 - 0.19 11.6 4.4 0.38 10.6 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KXX74940.1 - 0.31 11.0 5.7 0.55 10.2 5.7 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KXX74940.1 - 0.34 10.6 4.8 0.61 9.7 4.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KXX74940.1 - 0.45 10.7 3.4 1 9.5 3.4 1.6 1 1 0 1 1 1 0 RING-variant domain OAD_gamma PF04277.13 KXX74940.1 - 0.62 10.7 0.0 0.62 10.7 0.0 3.8 3 2 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain MSP1_C PF07462.11 KXX74940.1 - 5.1 5.7 5.1 7.9 5.0 5.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-UDP PF14569.6 KXX74940.1 - 5.7 7.1 7.6 0.65 10.2 2.3 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger Prok-RING_1 PF14446.6 KXX74940.1 - 9.1 6.3 9.1 0.23 11.4 1.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_M16 PF00675.20 KXX74941.1 - 5.3e-56 188.8 0.4 1e-55 187.8 0.4 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXX74941.1 - 2.3e-36 125.5 0.0 5.7e-35 121.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 KXX74941.1 - 0.023 13.8 0.1 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase M16C associated MTD PF01993.18 KXX74941.1 - 0.028 13.8 0.0 0.95 8.7 0.0 2.3 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase RbsD_FucU PF05025.13 KXX74941.1 - 0.031 14.7 0.1 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 RbsD / FucU transport protein family DUF3591 PF12157.8 KXX74942.1 - 6.3e-164 545.8 0.0 1e-163 545.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KXX74942.1 - 0.0056 16.7 0.7 0.0091 16.0 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KXX74942.1 - 0.019 14.8 0.4 0.047 13.5 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Tau95_N PF17682.1 KXX74942.1 - 0.048 13.8 1.0 0.14 12.3 1.0 1.8 1 0 0 1 1 1 0 Tau95 Triple barrel domain D-ser_dehydrat PF14031.6 KXX74943.1 - 4.9e-22 78.4 0.0 1.6e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXX74943.1 - 1.3e-10 41.3 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Actin PF00022.19 KXX74944.1 - 6.6e-146 486.1 0.0 7.5e-146 485.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXX74944.1 - 2.6e-05 23.2 0.0 0.015 14.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein PIG-P PF08510.12 KXX74945.1 - 3.1e-51 172.3 0.2 6.4e-51 171.3 0.2 1.5 1 0 0 1 1 1 1 PIG-P BUD22 PF09073.10 KXX74945.1 - 0.16 11.2 10.5 0.23 10.8 10.5 1.2 1 0 0 1 1 1 0 BUD22 DPM2 PF07297.12 KXX74945.1 - 0.24 11.7 9.3 0.39 11.1 9.3 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Phage_holin_3_6 PF07332.11 KXX74945.1 - 0.31 11.1 1.6 0.43 10.6 1.6 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EBV-NA3 PF05009.12 KXX74945.1 - 9.4 5.7 5.7 15 5.0 5.7 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF1713 PF08213.11 KXX74946.1 - 1e-07 31.7 21.0 1e-07 31.7 21.0 2.4 3 0 0 3 3 3 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KXX74946.1 - 0.0075 17.0 0.3 0.018 15.7 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial protein Pet20 DUF3391 PF11871.8 KXX74946.1 - 0.94 10.0 7.0 0.67 10.5 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Raffinose_syn PF05691.12 KXX74947.1 - 3.8e-54 183.7 1.7 1.9e-43 148.4 0.0 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.26 KXX74947.1 - 5e-07 29.3 0.4 6.8e-07 28.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 KXX74947.1 - 0.011 14.8 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 Melibiase Thioredoxin_4 PF13462.6 KXX74948.1 - 4.4e-09 36.7 0.0 7.5e-09 36.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KXX74948.1 - 0.0011 18.7 5.0 0.13 12.1 0.1 3.0 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KXX74948.1 - 0.066 13.3 0.3 0.12 12.4 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin domain TOM20_plant PF06552.12 KXX74948.1 - 0.067 12.9 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Pkinase PF00069.25 KXX74949.1 - 1.3e-69 234.5 0.0 2.6e-69 233.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74949.1 - 1.5e-49 168.6 0.0 2.6e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KXX74949.1 - 5.5e-27 94.0 0.0 1.1e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KXX74949.1 - 6.6e-18 64.6 0.5 2.6e-17 62.7 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXX74949.1 - 3e-16 59.6 0.1 5.9e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXX74949.1 - 1e-13 51.7 0.1 2.3e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KXX74949.1 - 1.7e-07 30.9 0.0 9.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 KXX74949.1 - 0.016 15.1 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KXX74949.1 - 0.027 13.3 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase SAM_PNT PF02198.16 KXX74949.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Brix PF04427.18 KXX74950.1 - 5.6e-22 78.8 0.0 1.2e-21 77.7 0.0 1.5 1 1 1 2 2 2 1 Brix domain BURP PF03181.15 KXX74950.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 BURP domain HGTP_anticodon PF03129.20 KXX74952.1 - 7.9e-24 83.6 0.0 7.9e-24 83.6 0.0 2.5 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXX74952.1 - 2.8e-08 33.9 0.0 2.8e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) LRR_6 PF13516.6 KXX74953.1 - 0.061 13.4 5.0 20 5.5 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 KXX74953.1 - 0.47 11.2 8.4 13 6.8 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich Repeat DUF3774 PF12609.8 KXX74953.1 - 1.6 9.8 4.2 0.74 10.9 0.4 2.4 2 0 0 2 2 2 0 Wound-induced protein TPT PF03151.16 KXX74954.1 - 2.3e-07 30.4 13.8 4e-07 29.7 13.8 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family Tuberculin PF12198.8 KXX74954.1 - 0.15 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Theoretical tuberculin protein Methyltransf_23 PF13489.6 KXX74955.1 - 1.2e-13 51.2 0.0 2.2e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX74955.1 - 2e-08 34.8 0.0 4.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX74955.1 - 7.3e-07 29.9 0.0 1.9e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX74955.1 - 9.2e-05 23.0 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX74955.1 - 9.8e-05 22.2 0.0 0.00038 20.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXX74955.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KXX74955.1 - 0.0058 16.0 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KXX74955.1 - 0.028 14.5 0.0 0.13 12.3 0.0 2.1 2 1 0 2 2 2 0 FtsJ-like methyltransferase CMAS PF02353.20 KXX74955.1 - 0.031 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXX74955.1 - 0.083 12.4 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KXX74955.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 KXX74956.1 - 2.5e-71 240.8 0.0 2.9e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXX74956.1 - 4e-58 196.7 0.1 4.8e-58 196.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXX74956.1 - 1.2e-22 80.4 0.0 1.2e-21 77.1 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXX74956.1 - 6.8e-21 74.5 0.0 9e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXX74956.1 - 1.6e-18 66.8 0.3 2.3e-17 63.0 0.3 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KXX74956.1 - 5.4e-18 65.1 0.0 6.7e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXX74956.1 - 8.2e-08 32.4 0.0 1.6e-07 31.4 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KXX74956.1 - 0.032 13.7 0.0 1.6 8.2 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase PUF PF00806.19 KXX74957.1 - 9.8e-26 88.0 0.0 8.8e-05 22.0 0.0 5.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KXX74957.1 - 6.6e-14 51.5 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDHD PF02862.17 KXX74957.1 - 0.002 18.3 1.8 0.0042 17.3 1.8 1.5 1 0 0 1 1 1 1 DDHD domain Apc15p PF05841.11 KXX74957.1 - 0.014 16.2 11.2 0.014 16.2 11.2 2.2 2 0 0 2 2 1 0 Apc15p protein Neur_chan_memb PF02932.16 KXX74957.1 - 0.022 14.8 2.6 0.041 13.9 2.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 KXX74957.1 - 0.043 13.6 4.4 0.079 12.8 4.4 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4834 PF16118.5 KXX74957.1 - 0.044 14.7 7.8 0.15 13.1 7.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Tim54 PF11711.8 KXX74957.1 - 0.2 10.4 6.6 0.54 9.0 6.6 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4175 PF13779.6 KXX74957.1 - 0.26 9.2 21.7 0.4 8.5 21.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM91_C PF14648.6 KXX74957.1 - 0.31 9.8 4.3 0.56 9.0 4.3 1.3 1 0 0 1 1 1 0 FAM91 C-terminus EPL1 PF10513.9 KXX74957.1 - 0.39 11.1 10.2 0.26 11.7 7.1 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF913 PF06025.12 KXX74957.1 - 0.43 9.5 5.1 0.83 8.6 5.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TERB2 PF15101.6 KXX74957.1 - 0.74 9.8 13.6 1.5 8.9 13.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 KXX74957.1 - 1.1 8.8 40.7 2.8 7.5 40.7 1.6 1 0 0 1 1 1 0 Spt20 family CobT PF06213.12 KXX74957.1 - 1.2 8.4 14.6 2.5 7.4 14.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM60A PF15396.6 KXX74957.1 - 1.8 8.5 5.9 4.1 7.4 5.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 KXX74957.1 - 1.9 7.2 14.1 3.1 6.4 14.1 1.2 1 0 0 1 1 1 0 Presenilin MAJIN PF15077.6 KXX74957.1 - 4 7.2 7.1 8.3 6.1 7.1 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein PAT1 PF09770.9 KXX74957.1 - 6.3 4.9 23.6 13 3.9 21.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 KXX74957.1 - 9.6 5.0 17.3 17 4.2 17.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 KXX74958.1 - 1e-70 238.1 0.1 1.8e-70 237.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74958.1 - 1.8e-53 181.5 0.1 3.2e-53 180.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXX74958.1 - 1.6e-23 82.8 0.9 6.5e-23 80.8 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.29 KXX74958.1 - 2e-07 31.5 0.0 4.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 KXX74958.1 - 5e-06 25.5 0.0 1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXX74958.1 - 1.1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXX74958.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KXX74958.1 - 0.027 14.4 5.9 0.091 12.7 0.2 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXX74958.1 - 0.032 13.2 0.8 0.067 12.1 0.3 1.5 1 1 0 1 1 1 0 Haspin like kinase domain PH_11 PF15413.6 KXX74958.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain RIO1 PF01163.22 KXX74958.1 - 0.36 10.4 0.0 0.36 10.4 0.0 2.5 3 0 0 3 3 3 0 RIO1 family Kdo PF06293.14 KXX74958.1 - 0.44 9.9 1.7 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nas2_N PF18265.1 KXX74959.1 - 5e-30 103.2 0.1 7e-30 102.8 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KXX74959.1 - 6.4e-08 32.3 0.1 1.5e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXX74959.1 - 4.6e-07 30.1 0.0 8.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KXX74959.1 - 5.7e-06 26.7 0.0 9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KXX74959.1 - 0.00024 21.4 0.1 0.0004 20.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Vert_HS_TF PF06546.11 KXX74959.1 - 0.064 12.9 0.0 2.6 7.6 0.0 2.0 2 0 0 2 2 2 0 Vertebrate heat shock transcription factor RhoGEF PF00621.20 KXX74960.1 - 2.4e-24 86.6 0.0 3.8e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain SBDS PF01172.18 KXX74962.1 - 8.7e-23 80.2 0.0 9.5e-23 80.1 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein CorA PF01544.18 KXX74962.1 - 0.046 13.0 0.0 0.057 12.7 0.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C2H2 PF00096.26 KXX74963.1 - 1e-05 25.7 21.2 0.0012 19.1 0.5 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX74963.1 - 0.0022 18.7 0.7 0.0022 18.7 0.7 4.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXX74963.1 - 0.046 13.7 0.3 0.046 13.7 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXX74963.1 - 0.32 11.4 4.5 0.077 13.3 0.4 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KXX74963.1 - 1.1 9.9 8.7 1.1 9.9 1.2 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF629 PF04780.12 KXX74963.1 - 1.6 7.2 7.2 4.1 5.8 6.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF629) WSC PF01822.19 KXX74964.1 - 3.4e-88 289.9 69.3 5.3e-20 71.4 12.1 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 KXX74964.1 - 1.2e-25 90.1 0.0 2.3e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KXX74964.1 - 5e-19 68.4 0.0 9.9e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 KXX74964.1 - 1.8 8.6 4.5 12 6.0 0.0 3.9 5 0 0 5 5 5 0 Kelch motif Opiods_neuropep PF01160.18 KXX74964.1 - 2.8 8.1 6.2 3.4 7.8 0.9 3.3 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide Ras PF00071.22 KXX74965.1 - 1.4e-43 148.3 0.1 3.9e-42 143.6 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXX74965.1 - 6e-30 103.9 0.0 9.6e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX74965.1 - 7.8e-10 38.5 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXX74965.1 - 0.00026 21.1 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXX74965.1 - 0.0065 15.9 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 KXX74965.1 - 0.0071 16.7 0.1 0.034 14.5 0.1 1.9 1 1 0 1 1 1 1 RNA helicase Pox_A32 PF04665.12 KXX74965.1 - 0.019 14.4 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KXX74965.1 - 0.025 14.1 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KXX74965.1 - 0.058 13.1 0.3 0.089 12.5 0.3 1.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX74965.1 - 0.098 13.0 0.2 0.11 12.9 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXX74965.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXX74965.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 KXX74965.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATPase PF06745.13 KXX74965.1 - 0.14 11.5 0.2 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 KaiC Septin PF00735.18 KXX74965.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Septin STAS PF01740.21 KXX74965.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 STAS domain G-alpha PF00503.20 KXX74965.1 - 0.28 10.3 1.2 1.7 7.7 0.2 2.4 2 1 1 3 3 3 0 G-protein alpha subunit RRN3 PF05327.11 KXX74966.1 - 1.6e-158 528.8 0.0 1.6e-158 528.8 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 MIF4G PF02854.19 KXX74966.1 - 9.3 5.8 7.1 59 3.2 7.2 2.2 1 1 0 1 1 1 0 MIF4G domain bZIP_1 PF00170.21 KXX74967.1 - 0.18 11.9 9.3 3.7 7.7 9.3 2.2 1 1 0 1 1 1 0 bZIP transcription factor Prefoldin_2 PF01920.20 KXX74968.1 - 4.8e-26 90.8 6.1 5.4e-26 90.6 6.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2089 PF09862.9 KXX74968.1 - 0.0031 17.5 1.4 0.018 15.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) DUF4757 PF15949.5 KXX74968.1 - 0.018 15.6 1.0 0.027 14.9 1.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4757) DUF2205 PF10224.9 KXX74968.1 - 0.018 15.0 5.9 0.059 13.4 0.9 2.1 2 0 0 2 2 2 0 Short coiled-coil protein SLATT_1 PF18181.1 KXX74968.1 - 0.12 12.3 2.2 0.24 11.3 0.5 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 CBFD_NFYB_HMF PF00808.23 KXX74969.1 - 1.7e-29 101.9 1.0 2.3e-29 101.5 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXX74969.1 - 1.9e-06 28.3 0.2 3.9e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KXX74969.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 KXX74969.1 - 0.0015 18.5 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KXX74969.1 - 0.0026 17.8 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KXX74969.1 - 0.06 13.9 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Tmemb_14 PF03647.13 KXX74970.1 - 1e-23 83.9 5.1 1.2e-23 83.6 5.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KXX74970.1 - 0.00087 19.6 0.3 0.004 17.4 0.3 1.8 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 CytB6-F_Fe-S PF08802.10 KXX74970.1 - 2 8.5 6.2 1.7 8.7 0.2 2.8 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Cmc1 PF08583.10 KXX74971.1 - 9e-17 60.9 2.1 1.1e-16 60.6 2.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 KXX74971.1 - 0.57 10.6 4.4 0.56 10.7 2.9 1.7 1 1 1 2 2 2 0 GCK domain DHDPS PF00701.22 KXX74972.1 - 7.9e-38 129.8 0.0 9.3e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Methyltransf_25 PF13649.6 KXX74972.1 - 0.04 14.6 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 KXX74974.1 - 8.1e-23 80.3 22.1 1.5e-05 25.7 0.2 6.9 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX74974.1 - 1.3e-11 44.6 6.7 1.7e-05 25.0 0.2 4.1 2 2 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KXX74974.1 - 0.00054 19.9 5.1 0.22 11.4 0.6 2.7 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 KXX74974.1 - 0.063 11.3 2.3 0.31 9.0 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Ge1_WD40 PF16529.5 KXX74974.1 - 0.069 12.1 0.9 2.2 7.2 0.0 3.3 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GSDH PF07995.11 KXX74975.1 - 0.00021 20.7 0.1 0.0015 17.9 0.1 2.3 3 0 0 3 3 3 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 KXX74975.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KXX74975.1 - 0.048 12.9 0.1 4.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase PF00069.25 KXX74976.1 - 2.6e-29 102.4 0.0 1.4e-28 100.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74976.1 - 5.6e-07 29.1 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase CSTF2_hinge PF14327.6 KXX74976.1 - 0.068 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Terpene_synth_C PF03936.16 KXX74977.1 - 0.00019 20.9 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF1604 PF07713.13 KXX74979.1 - 6.5e-42 141.3 0.8 2.4e-41 139.5 0.8 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KXX74979.1 - 2.4e-06 27.3 2.0 4.8e-06 26.4 0.9 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXX74979.1 - 0.0086 16.1 0.9 0.06 13.4 0.2 2.9 2 0 0 2 2 2 1 G-patch domain Pkinase PF00069.25 KXX74980.1 - 3.5e-67 226.6 0.0 5.1e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX74980.1 - 1.1e-38 133.1 0.0 2e-38 132.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KXX74980.1 - 3.1e-19 68.5 0.1 8.4e-19 67.1 0.1 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KXX74980.1 - 1.5e-06 27.7 0.2 2.7e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXX74980.1 - 9e-05 21.9 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXX74980.1 - 0.00044 19.3 0.0 0.00071 18.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXX74980.1 - 0.0012 18.9 2.5 0.0027 17.7 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 KXX74980.1 - 0.034 13.8 0.1 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KXX74980.1 - 0.055 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KXX74980.1 - 0.21 10.3 0.0 0.21 10.3 0.0 2.1 3 0 0 3 3 3 0 Fungal protein kinase DOPA_dioxygen PF08883.11 KXX74981.1 - 9.9e-43 144.7 0.0 1.2e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF2014 PF09427.10 KXX74982.1 - 2e-113 378.1 8.1 3e-113 377.6 8.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KXX74982.1 - 9.4e-17 60.7 0.9 1.9e-16 59.8 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain hNIFK_binding PF12196.8 KXX74982.1 - 0.31 10.5 2.9 0.92 9.1 2.9 1.8 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK UvrD_C PF13361.6 KXX74984.1 - 4.4e-63 213.8 0.0 7.4e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXX74984.1 - 9.2e-61 206.1 0.0 4.1e-59 200.7 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KXX74984.1 - 1.1e-29 103.7 0.0 2.4e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KXX74984.1 - 8.7e-15 54.3 0.1 4.1e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXX74984.1 - 2.8e-07 30.4 0.1 0.00038 20.2 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KXX74984.1 - 8.4e-06 25.5 0.0 7.2e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KXX74984.1 - 5.3e-05 23.1 0.1 0.48 10.1 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase CcmD PF04995.14 KXX74985.1 - 0.75 9.9 6.4 0.076 13.1 1.0 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) G-alpha PF00503.20 KXX74986.1 - 5.5e-124 413.9 1.3 6.3e-124 413.7 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXX74986.1 - 2.9e-15 56.1 1.3 3.5e-10 39.6 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KXX74986.1 - 0.00021 21.1 0.0 0.00089 19.0 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KXX74986.1 - 0.0017 17.7 3.1 0.083 12.2 0.0 2.7 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KXX74986.1 - 0.017 14.8 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KXX74986.1 - 0.02 15.1 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KXX74986.1 - 0.022 13.9 0.1 0.088 11.9 0.0 1.8 1 1 1 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KXX74986.1 - 0.095 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 KXX74986.1 - 0.14 11.7 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX74986.1 - 0.19 11.8 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase HEAT PF02985.22 KXX74988.1 - 5.3e-08 32.5 2.9 0.27 11.6 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KXX74988.1 - 3.5e-05 24.1 5.8 0.0078 16.6 0.1 4.9 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KXX74988.1 - 0.012 16.1 7.5 13 6.5 0.0 6.1 6 0 0 6 6 6 0 HEAT-like repeat Cnd1 PF12717.7 KXX74988.1 - 0.021 14.8 0.0 0.95 9.5 0.0 3.5 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SpoVR PF04293.13 KXX74988.1 - 0.039 12.7 0.2 0.097 11.3 0.2 1.6 1 0 0 1 1 1 0 SpoVR like protein DUF3734 PF12536.8 KXX74988.1 - 0.12 12.8 2.8 0.76 10.1 0.2 3.4 3 0 0 3 3 3 0 Patatin phospholipase SPESP1 PF15754.5 KXX74988.1 - 3.2 6.9 10.4 9.7 5.3 10.4 1.8 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF543 PF04418.12 KXX74989.1 - 2.5e-30 104.3 0.0 2.9e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ABC_cobalt PF09819.9 KXX74989.1 - 0.045 13.9 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component RasGEF PF00617.19 KXX74990.1 - 0.0014 18.8 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain D123 PF07065.14 KXX74991.1 - 2.5e-101 338.9 1.3 2e-50 171.7 0.1 2.2 1 1 1 2 2 2 2 D123 Urb2 PF10441.9 KXX74992.1 - 7.1e-70 235.1 1.0 2e-69 233.6 1.0 1.8 1 0 0 1 1 1 1 Urb2/Npa2 family cwf21 PF08312.12 KXX74993.1 - 1.3e-17 63.7 15.4 1.3e-17 63.7 15.4 2.1 2 0 0 2 2 2 1 cwf21 domain YabA PF06156.13 KXX74993.1 - 1 10.0 11.6 7.7 7.2 5.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Fungal_trans PF04082.18 KXX74994.1 - 7.1e-15 54.7 1.4 1.1e-14 54.1 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXX74994.1 - 8e-07 29.2 13.1 7.7e-05 22.9 5.5 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXX74994.1 - 0.00095 19.5 14.3 0.039 14.4 5.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX74994.1 - 0.0016 19.1 12.6 0.27 12.2 4.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KXX74994.1 - 0.042 14.5 0.9 2.6 8.7 0.4 2.7 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KXX74994.1 - 2 8.6 3.7 5.9 7.1 3.7 1.9 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KXX74994.1 - 3.2 8.2 7.8 1.4 9.3 3.7 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RasGEF PF00617.19 KXX74995.1 - 4.4e-47 160.6 0.2 9.1e-47 159.5 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXX74995.1 - 1.3e-27 96.1 0.3 2.8e-27 95.0 0.3 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KXX74995.1 - 7.5e-16 57.5 0.1 1.8e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX74995.1 - 9.4e-14 51.0 0.1 2e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX74995.1 - 1.9e-13 49.8 0.1 4e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KXX74995.1 - 1.7e-05 24.8 0.0 3.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 WW domain DUF1944 PF09175.10 KXX74995.1 - 0.043 13.7 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) Glyco_hydro_16 PF00722.21 KXX74996.1 - 4.9e-12 45.7 0.0 9.1e-12 44.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 GHD PF17834.1 KXX74996.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase DUF1771 PF08590.10 KXX74997.1 - 2.3e-22 79.1 7.9 4.3e-22 78.2 7.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KXX74997.1 - 1.2e-12 48.0 0.4 2.6e-12 46.9 0.4 1.6 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 KXX74997.1 - 0.23 10.8 2.3 0.29 10.4 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VPS53_C PF16854.5 KXX74998.1 - 0.026 14.4 0.0 0.19 11.6 0.0 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus GDE_C PF06202.14 KXX74998.1 - 0.08 11.9 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase YjbE PF11106.8 KXX74999.1 - 1.3 9.3 9.4 0.07 13.3 2.2 2.6 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Mito_carr PF00153.27 KXX75000.1 - 5e-44 148.2 6.3 3.7e-17 62.0 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KXX75000.1 - 0.0013 18.0 0.6 0.021 14.0 0.1 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease DUF3337 PF11816.8 KXX75001.1 - 3.4e-56 189.8 0.0 7.9e-56 188.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KXX75001.1 - 1.6e-16 60.3 10.8 0.00018 22.2 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KXX75001.1 - 0.0046 15.7 0.1 0.016 13.8 0.1 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXX75001.1 - 0.012 15.9 0.1 0.056 13.8 0.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain ATP_bind_3 PF01171.20 KXX75002.1 - 2.4e-35 121.9 0.0 6.3e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Utp13 PF08625.11 KXX75002.1 - 0.11 12.4 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain PPTA PF01239.22 KXX75003.1 - 9.5e-31 104.6 12.6 5.4e-07 29.1 1.2 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Med3 PF11593.8 KXX75003.1 - 0.033 13.4 1.6 0.045 12.9 1.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAM199X PF15814.5 KXX75003.1 - 0.095 11.7 2.7 0.14 11.1 2.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF3950 PF13132.6 KXX75003.1 - 0.12 12.1 0.5 9.5 6.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) Orthopox_A5L PF06193.11 KXX75003.1 - 0.28 10.6 3.9 0.5 9.8 3.9 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Sporozoite_P67 PF05642.11 KXX75003.1 - 0.61 8.1 3.7 0.75 7.8 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_pp85 PF04637.12 KXX75003.1 - 3.4 6.0 6.5 6.1 5.1 6.5 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HCMVantigenic_N PF12154.8 KXX75004.1 - 0.28 11.3 1.1 0.53 10.4 1.1 1.4 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV His_Phos_2 PF00328.22 KXX75008.1 - 0.024 14.0 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Mito_carr PF00153.27 KXX75009.1 - 4.5e-68 225.3 3.9 1.9e-25 88.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TetR_C_14 PF17754.1 KXX75009.1 - 0.057 13.4 0.3 0.8 9.7 0.1 2.4 2 0 0 2 2 2 0 MftR C-terminal domain Serine_protease PF18405.1 KXX75009.1 - 0.46 9.6 4.3 29 3.7 0.0 3.6 3 1 1 4 4 4 0 Gammaproteobacterial serine protease NAP PF00956.18 KXX75010.1 - 4.2e-10 39.3 0.0 5.7e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Metallophos PF00149.28 KXX75011.1 - 2.3e-09 38.1 0.0 4.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX75011.1 - 0.00022 21.5 0.9 0.0081 16.4 0.9 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2278 PF10042.9 KXX75013.1 - 5.2e-64 216.0 0.0 6.6e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.19 KXX75013.1 - 2.7e-08 34.1 0.1 7e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 Lamin Tail Domain Exo_endo_phos PF03372.23 KXX75014.1 - 1.2e-06 28.3 0.1 1.3e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KXX75014.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase FAD_binding_4 PF01565.23 KXX75015.1 - 6.3e-24 84.3 2.4 6.7e-24 84.2 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXX75015.1 - 6.5e-07 29.4 0.0 1.7e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like DLH PF01738.18 KXX75015.1 - 0.084 12.4 1.1 0.14 11.7 1.1 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family ketoacyl-synt PF00109.26 KXX75016.1 - 3.3e-77 259.5 0.1 2.8e-76 256.4 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXX75016.1 - 9.9e-74 248.4 0.2 2.7e-73 247.0 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KXX75016.1 - 5.8e-65 219.7 0.0 8.1e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KXX75016.1 - 1.4e-53 181.5 0.0 2e-51 174.5 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KXX75016.1 - 9.9e-46 156.3 0.8 1.7e-45 155.5 0.8 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX75016.1 - 1.9e-33 116.3 0.4 3.8e-33 115.3 0.4 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX75016.1 - 7.4e-31 106.6 0.1 1.6e-29 102.3 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXX75016.1 - 2e-30 105.9 0.0 3.8e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KXX75016.1 - 2.2e-20 73.2 0.0 6.3e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXX75016.1 - 1.7e-15 57.1 1.5 6.4e-09 36.1 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 KXX75016.1 - 2.9e-14 53.1 0.0 1.8e-12 47.3 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KXX75016.1 - 3.1e-14 53.4 0.0 1.4e-13 51.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX75016.1 - 6.3e-14 51.9 0.1 5e-11 42.4 0.0 4.3 5 0 0 5 5 5 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KXX75016.1 - 6.3e-12 46.0 0.0 2e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX75016.1 - 7.1e-12 45.5 0.0 1.5e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXX75016.1 - 1.5e-10 41.5 0.0 3.8e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KXX75016.1 - 9.6e-08 32.0 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KXX75016.1 - 1.1e-06 27.9 0.0 3.1e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 KXX75016.1 - 2e-06 27.3 0.0 4.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KXX75016.1 - 8.5e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KXX75016.1 - 0.00025 20.5 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 KXX75016.1 - 0.00046 21.1 0.1 0.0042 18.0 0.0 2.8 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain ACP_syn_III PF08545.10 KXX75016.1 - 0.0036 17.1 0.7 0.011 15.6 0.7 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.9 KXX75016.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 KXX75016.1 - 0.071 14.1 1.4 2.9 8.9 0.0 3.9 4 0 0 4 4 3 0 Methyltransferase domain Methyltransf_33 PF10017.9 KXX75016.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent SKG6 PF08693.10 KXX75017.1 - 2.2e-05 23.8 1.1 4.1e-05 22.9 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GCR1_C PF12550.8 KXX75018.1 - 2.6e-11 43.7 0.4 3.2e-11 43.4 0.4 1.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SNO PF01174.19 KXX75019.1 - 5.7e-42 143.7 0.0 7.4e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXX75019.1 - 4.8e-09 36.1 0.0 6.2e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KXX75019.1 - 8.8e-05 22.2 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 KXX75019.1 - 0.0025 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_13 PF11972.8 KXX75019.1 - 0.043 13.9 0.4 15 5.7 0.2 2.7 2 0 0 2 2 2 0 HTH DNA binding domain SR-25 PF10500.9 KXX75019.1 - 1.3 8.6 8.2 2.1 7.9 8.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KXX75019.1 - 2.9 8.6 8.3 0.12 13.0 2.5 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein OTT_1508_deam PF14441.6 KXX75020.1 - 1.7e-19 69.5 0.0 3.3e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase FlgN PF05130.12 KXX75020.1 - 0.085 13.4 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 FlgN protein FANCI_S3 PF14677.6 KXX75020.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 FANCI solenoid 3 FAR1 PF03101.15 KXX75021.1 - 8e-09 36.1 0.3 8e-09 36.1 0.3 1.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain OmpH PF03938.14 KXX75021.1 - 0.32 11.3 19.8 0.72 10.2 19.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Presenilin PF01080.17 KXX75021.1 - 1.3 7.7 5.6 1.6 7.4 5.6 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 KXX75021.1 - 2.4 7.6 10.3 3.3 7.2 10.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4175 PF13779.6 KXX75021.1 - 6 4.6 37.1 1.4 6.7 34.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) PAT1 PF09770.9 KXX75021.1 - 8.8 4.5 21.4 12 4.0 21.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AFT PF08731.11 KXX75021.1 - 9 6.7 9.1 4.8 7.6 5.6 2.3 2 1 0 2 2 2 0 Transcription factor AFT Zn_clus PF00172.18 KXX75023.1 - 1.9e-10 40.7 13.1 2.9e-10 40.1 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COX15-CtaA PF02628.15 KXX75024.1 - 1.1e-112 376.3 4.5 1.5e-112 375.9 4.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein FixS PF03597.15 KXX75024.1 - 0.5 10.1 2.7 20 5.0 0.3 3.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type RskA PF10099.9 KXX75024.1 - 8.6 6.6 10.9 2.7 8.3 0.1 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Copper-fist PF00649.18 KXX75025.1 - 3.7e-22 77.5 3.9 3.7e-22 77.5 3.9 3.6 1 1 3 4 4 4 1 Copper fist DNA binding domain Leu_leader PF08054.11 KXX75025.1 - 0.22 11.1 0.2 7.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Leucine operon leader peptide TMF_DNA_bd PF12329.8 KXX75026.1 - 0.0011 19.0 5.5 0.0011 19.0 5.5 15.0 7 4 7 16 16 16 4 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KXX75026.1 - 0.0012 18.6 20.2 0.44 10.4 0.6 7.0 5 1 1 6 6 6 4 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KXX75026.1 - 0.0033 16.3 28.8 0.0033 16.3 28.8 9.3 2 1 8 10 10 10 6 Spc7 kinetochore protein Filament PF00038.21 KXX75026.1 - 0.43 10.1 156.7 0.027 14.1 30.9 6.4 1 1 4 6 6 6 0 Intermediate filament protein Fib_alpha PF08702.10 KXX75026.1 - 0.65 10.2 0.0 0.65 10.2 0.0 9.4 2 1 7 10 10 10 0 Fibrinogen alpha/beta chain family ApbA PF02558.16 KXX75029.1 - 3.2e-31 108.0 0.0 4.9e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXX75029.1 - 8e-26 90.7 0.0 1.5e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NPR1_interact PF15699.5 KXX75029.1 - 0.11 13.1 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 NPR1 interacting ADH_N PF08240.12 KXX75030.1 - 1.6e-24 85.9 5.9 2.6e-24 85.2 5.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX75030.1 - 1.1e-18 67.5 0.2 2.6e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXX75030.1 - 0.0039 16.5 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXX75030.1 - 0.038 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Wyosine_form PF08608.12 KXX75030.1 - 0.086 13.2 0.2 6.7 7.1 0.2 2.4 1 1 0 1 1 1 0 Wyosine base formation Zip PF02535.22 KXX75031.1 - 5.3e-50 170.5 0.0 8.3e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter NAD_binding_8 PF13450.6 KXX75032.1 - 1.5e-13 50.7 0.1 3.1e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX75032.1 - 0.00011 22.0 0.3 0.00047 19.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXX75032.1 - 0.011 14.8 0.2 0.029 13.4 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXX75032.1 - 0.019 14.9 0.7 0.3 11.1 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXX75032.1 - 0.031 13.5 0.1 0.072 12.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KXX75032.1 - 0.037 12.9 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KXX75032.1 - 0.043 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2834 PF11196.8 KXX75033.1 - 1.3e-07 31.9 18.8 0.0021 18.4 11.1 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) DUF3397 PF11877.8 KXX75033.1 - 1.9 8.7 14.2 1.3 9.2 0.3 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3397) DNA_methylase PF00145.17 KXX75034.1 - 4.4e-34 118.3 0.0 1e-25 90.9 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.18 KXX75034.1 - 4.7e-06 26.4 0.0 0.052 13.4 0.0 2.4 2 0 0 2 2 2 2 BAH domain Methyltransf_33 PF10017.9 KXX75035.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 KXX75035.1 - 0.098 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Drc1-Sld2 PF11719.8 KXX75037.1 - 1.8e-83 281.6 21.7 5.7e-83 280.0 21.7 1.7 1 1 0 1 1 1 1 DNA replication and checkpoint protein DUF5137 PF17220.3 KXX75037.1 - 0.13 13.1 0.3 0.13 13.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5137) zf-RING_2 PF13639.6 KXX75038.1 - 5.5e-08 33.0 11.8 9.2e-08 32.3 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX75038.1 - 2.1e-06 27.5 7.0 3.3e-06 26.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX75038.1 - 5.2e-06 26.2 12.3 1e-05 25.2 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX75038.1 - 1.2e-05 25.1 8.1 1.9e-05 24.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX75038.1 - 4.7e-05 23.6 10.7 0.00017 21.8 10.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXX75038.1 - 0.1 12.6 4.7 0.21 11.6 4.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger GAGA PF09237.11 KXX75038.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.2 3 0 0 3 3 3 0 GAGA factor zf-ANAPC11 PF12861.7 KXX75038.1 - 0.24 11.5 3.0 0.56 10.3 3.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXX75038.1 - 0.92 9.4 7.0 1.7 8.5 7.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXX75038.1 - 1.7 8.5 7.6 3.9 7.3 7.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 KXX75038.1 - 3.8 7.4 5.8 7 6.5 5.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KXX75038.1 - 7.1 6.7 8.6 12 5.9 8.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Rpn3_C PF08375.11 KXX75039.1 - 6.2e-26 90.6 1.7 1.8e-25 89.1 1.7 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KXX75039.1 - 2.4e-20 73.0 1.1 9.7e-20 71.0 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 KXX75039.1 - 0.017 15.2 0.1 0.057 13.6 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TFIID_20kDa PF03847.13 KXX75040.1 - 4.5e-18 65.5 0.0 7.9e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A ASD2 PF08687.11 KXX75040.1 - 0.34 10.4 8.8 0.54 9.8 0.3 2.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DASH_Spc34 PF08657.10 KXX75042.1 - 1.7e-53 182.0 0.0 1.4e-28 100.4 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KXX75042.1 - 1.1 9.2 8.0 1.5 8.7 8.0 1.2 1 0 0 1 1 1 0 Spc19 DSBA PF01323.20 KXX75043.1 - 1.2e-40 139.4 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXX75043.1 - 0.00012 22.2 0.0 0.00036 20.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KXX75043.1 - 0.00075 19.5 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain CNOT1_CAF1_bind PF16415.5 KXX75044.1 - 0.044 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Sugar_tr PF00083.24 KXX75045.1 - 3.8e-83 279.8 17.7 4.5e-83 279.6 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX75045.1 - 2.4e-26 92.5 17.9 3.5e-26 92.0 17.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXX75045.1 - 1.8e-05 23.5 11.0 0.0043 15.7 1.7 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 KXX75045.1 - 0.00015 20.3 4.1 0.00053 18.5 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 KXX75045.1 - 0.0071 15.2 0.9 0.0071 15.2 0.9 2.0 2 0 0 2 2 2 1 POT family MFS_1 PF07690.16 KXX75047.1 - 1e-26 93.8 30.1 1.6e-26 93.1 30.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXX75047.1 - 1.1e-06 27.9 0.0 2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX75047.1 - 1.5e-05 25.0 10.0 2.7e-05 24.2 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KXX75047.1 - 0.045 13.6 0.4 0.094 12.6 0.4 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat IF-2B PF01008.17 KXX75048.1 - 4.4e-20 72.0 0.0 1e-19 70.9 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KXX75048.1 - 1.4e-11 44.5 0.0 3.8e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Nucleotid_trans PF03407.16 KXX75050.1 - 1.5e-08 34.9 0.0 2.4e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TraQ PF09679.10 KXX75052.1 - 0.15 12.0 0.1 0.43 10.5 0.1 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) PSD5 PF07637.11 KXX75052.1 - 3.2 8.2 4.9 49 4.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) Lactonase PF10282.9 KXX75053.1 - 2.9e-88 296.4 0.0 3.8e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HpcH_HpaI PF03328.14 KXX75054.1 - 8.7e-06 25.0 0.0 2e-05 23.8 0.0 1.5 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Methyltransf_23 PF13489.6 KXX75055.1 - 1.9e-18 66.9 0.0 2.6e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX75055.1 - 9.3e-15 55.1 0.0 1.9e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX75055.1 - 2.6e-13 50.5 0.0 6.7e-13 49.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX75055.1 - 1.9e-10 41.4 0.0 6.2e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX75055.1 - 9.6e-09 35.2 0.0 2.7e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX75055.1 - 1.4e-07 31.2 0.0 1.7e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXX75055.1 - 0.0025 17.3 0.0 0.0083 15.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXX75055.1 - 0.016 14.7 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.15 KXX75055.1 - 0.019 14.8 0.0 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase PrmA PF06325.13 KXX75055.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXX75055.1 - 0.063 13.0 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MARVEL PF01284.23 KXX75056.1 - 0.0022 18.0 0.9 0.0031 17.6 0.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2273 PF10031.9 KXX75056.1 - 0.066 13.2 1.3 0.066 13.2 1.3 1.6 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF2070 PF09843.9 KXX75056.1 - 0.2 9.9 2.3 0.23 9.7 2.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ferlin_C PF16165.5 KXX75056.1 - 1.3 8.9 2.6 2 8.4 2.6 1.2 1 0 0 1 1 1 0 Ferlin C-terminus F-box PF00646.33 KXX75057.1 - 0.0003 20.6 0.1 0.00087 19.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXX75057.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KXX75057.1 - 0.013 15.4 0.1 0.039 13.9 0.1 1.9 1 0 0 1 1 1 0 F-box-like zf-ribbon_3 PF13248.6 KXX75057.1 - 0.048 13.1 1.6 0.71 9.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain PAN_4 PF14295.6 KXX75058.1 - 5.5e-05 23.0 0.2 0.00012 22.0 0.2 1.5 1 0 0 1 1 1 1 PAN domain ODV-E18 PF10717.9 KXX75058.1 - 0.061 13.2 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Glyco_hydro_61 PF03443.14 KXX75059.1 - 1.1e-55 188.8 0.3 1.3e-55 188.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 YbfN PF13982.6 KXX75060.1 - 0.044 14.1 0.8 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 YbfN-like lipoprotein cwf21 PF08312.12 KXX75060.1 - 0.13 12.5 0.1 15 5.9 0.0 2.3 2 0 0 2 2 2 0 cwf21 domain p450 PF00067.22 KXX75061.1 - 1.9e-56 191.8 0.0 2.5e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KXX75063.1 - 2.9e-31 109.0 0.0 2.1e-28 99.6 0.0 3.1 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX75063.1 - 8.5e-31 107.4 0.0 1.4e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXX75063.1 - 0.00096 19.3 0.1 0.0022 18.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX75063.1 - 0.0061 15.8 0.1 0.011 15.0 0.1 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX75063.1 - 0.02 14.5 4.6 1.2 8.6 1.6 3.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXX75063.1 - 0.026 13.8 0.2 0.039 13.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXX75063.1 - 0.031 13.0 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXX75063.1 - 0.067 12.4 0.0 6.6 5.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX75063.1 - 0.073 12.1 1.2 0.16 11.0 0.7 1.7 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KXX75063.1 - 0.18 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MIP PF00230.20 KXX75064.1 - 5.1e-47 160.5 12.8 6.5e-47 160.1 12.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Vut_1 PF02592.15 KXX75064.1 - 0.68 10.2 10.9 5.6 7.3 2.4 2.6 2 1 0 2 2 2 0 Putative vitamin uptake transporter Hydrolase_6 PF13344.6 KXX75065.1 - 7.8e-08 32.4 0.0 2.1e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase p450 PF00067.22 KXX75066.1 - 2.4e-49 168.4 0.0 3.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 KXX75067.1 - 1.9e-19 70.4 0.0 3.6e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX75067.1 - 0.00011 22.6 0.0 0.0018 18.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXX75067.1 - 0.00028 20.7 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXX75067.1 - 0.01 16.1 0.1 0.048 13.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXX75067.1 - 0.023 15.2 0.1 0.15 12.6 0.0 2.5 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KXX75067.1 - 0.032 14.2 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KXX75067.1 - 0.082 12.7 5.8 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain HET-s_218-289 PF11558.8 KXX75067.1 - 0.091 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Het-s 218-289 NPR3 PF03666.13 KXX75067.1 - 0.2 10.4 9.5 1.8 7.2 8.1 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 KXX75067.1 - 1.8 8.3 14.1 16 5.3 16.0 1.5 2 0 0 2 2 2 0 SpoIIIAH-like protein SURF2 PF05477.11 KXX75067.1 - 1.9 8.1 11.9 1.5e+02 2.0 13.6 2.3 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.12 KXX75067.1 - 3.2 7.0 11.2 6.3 6.0 11.2 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KXX75067.1 - 3.6 5.7 18.1 5.5 5.1 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 KXX75067.1 - 5.8 6.7 13.5 11 5.8 13.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4637 PF15470.6 KXX75067.1 - 7.6 6.2 12.7 14 5.4 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ank_2 PF12796.7 KXX75069.1 - 7e-100 327.8 0.0 1.7e-15 57.3 0.0 7.5 3 1 9 12 12 12 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX75069.1 - 2.4e-51 171.5 0.0 6.2e-10 39.4 0.0 8.8 3 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75069.1 - 4.6e-50 161.7 0.0 8.5e-06 25.8 0.0 14.2 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 KXX75069.1 - 5.8e-46 154.0 2.5 2.1e-06 27.9 0.0 11.6 2 2 10 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KXX75069.1 - 9.3e-43 142.9 0.0 0.00012 22.4 0.0 12.4 12 0 0 12 12 12 9 Ankyrin repeat Glyoxalase PF00903.25 KXX75071.1 - 0.00043 20.5 0.0 0.00078 19.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PIP5K PF01504.18 KXX75075.1 - 5e-48 163.7 0.0 1.3e-47 162.4 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Zn_clus PF00172.18 KXX75077.1 - 7.6e-09 35.6 10.1 1.4e-08 34.7 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX75077.1 - 3.4e-05 23.0 0.0 6.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 KXX75078.1 - 0.04 13.9 0.2 0.063 13.3 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 KXX75080.1 - 2.5e-10 39.8 16.8 1e-09 37.8 8.1 3.4 2 1 0 3 3 3 2 Major Facilitator Superfamily DHHC PF01529.20 KXX75081.1 - 2.2e-33 115.2 11.2 2.2e-33 115.2 11.2 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KXX75081.1 - 1.7e-25 89.4 0.0 2.9e-12 47.0 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX75081.1 - 1.4e-21 76.2 0.0 1.7e-06 28.2 0.0 4.9 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX75081.1 - 5.4e-21 74.7 0.2 1.6e-06 28.6 0.2 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75081.1 - 1.5e-20 71.1 0.6 4.4e-07 29.7 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KXX75081.1 - 1.7e-19 69.3 0.2 0.00034 20.9 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat lci PF12197.8 KXX75081.1 - 0.15 11.9 0.5 0.36 10.7 0.5 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein PocR PF10114.9 KXX75081.1 - 0.61 9.8 3.1 1.1 9.0 3.1 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR DLH PF01738.18 KXX75082.1 - 7.8e-29 100.8 0.0 9.9e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXX75082.1 - 0.13 11.8 0.0 0.38 10.4 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold PALP PF00291.25 KXX75083.1 - 1.7e-67 227.9 0.3 2.4e-67 227.4 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KXX75083.1 - 1.3e-12 48.0 0.0 2.1e-08 34.4 0.0 3.4 3 0 0 3 3 3 2 CBS domain FLgD_tudor PF13861.6 KXX75083.1 - 0.14 12.5 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 FlgD Tudor-like domain SRPRB PF09439.10 KXX75084.1 - 3.4e-22 78.7 0.0 6.5e-15 55.0 0.0 3.2 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KXX75084.1 - 8.1e-05 23.1 1.0 0.00027 21.4 0.9 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXX75084.1 - 0.0028 18.2 0.0 0.0037 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXX75084.1 - 0.0045 17.1 0.0 0.021 14.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXX75084.1 - 0.0056 16.1 0.0 0.52 9.7 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 KXX75084.1 - 0.018 15.5 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KXX75084.1 - 0.025 14.2 0.1 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KXX75084.1 - 0.025 14.8 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXX75084.1 - 0.034 14.1 0.0 0.31 10.9 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase TniB PF05621.11 KXX75084.1 - 0.035 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KXX75084.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX75084.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXX75084.1 - 0.23 11.2 0.1 0.23 11.2 0.1 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain RNase_P_pop3 PF08228.11 KXX75085.1 - 4.7e-12 46.2 0.0 6.1e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 Pkinase_fungal PF17667.1 KXX75086.1 - 2.2e-122 408.8 0.0 2.8e-122 408.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pyr_redox_2 PF07992.14 KXX75086.1 - 5.2e-41 140.8 0.0 1.1e-39 136.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX75086.1 - 1.5e-09 38.2 0.0 9.8e-08 32.4 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXX75086.1 - 5.3e-05 22.7 0.0 9.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pyr_redox_3 PF13738.6 KXX75086.1 - 0.09 12.0 0.1 3.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Anillin PF08174.11 KXX75087.1 - 2.3e-13 50.8 0.0 6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KXX75087.1 - 4.7e-07 30.3 0.0 1.4e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF4602 PF15375.6 KXX75089.1 - 6.7e-07 29.7 15.5 2.4e-05 24.7 15.5 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) CENP-B_dimeris PF09026.10 KXX75089.1 - 0.45 10.9 9.9 1.5 9.3 9.9 1.9 1 1 0 1 1 1 0 Centromere protein B dimerisation domain His_biosynth PF00977.21 KXX75090.1 - 1.9e-35 122.4 0.0 2.5e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KXX75090.1 - 0.14 11.5 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4778 PF16008.5 KXX75091.1 - 6.9 6.6 18.8 0.29 11.1 7.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Baculo_PEP_C PF04513.12 KXX75092.1 - 0.086 12.9 3.9 0.13 12.3 3.9 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CRIM PF16978.5 KXX75093.1 - 1.2e-45 155.1 0.0 2.4e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KXX75093.1 - 3.3e-32 111.0 0.0 6.3e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KXX75093.1 - 0.0039 17.4 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain PRCC PF10253.9 KXX75094.1 - 3.5e-33 116.2 7.2 3.5e-33 116.2 7.2 3.4 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF3517 PF12030.8 KXX75096.1 - 1.6e-111 372.5 0.0 2.5e-111 371.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KXX75096.1 - 4.6e-36 124.6 0.3 8.2e-36 123.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX75096.1 - 8.1e-20 71.6 0.2 1.8e-19 70.5 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SLD5_C PF16922.5 KXX75097.1 - 8.9e-12 45.0 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KXX75097.1 - 4.9e-09 36.6 0.7 1e-08 35.6 0.3 1.7 2 0 0 2 2 2 1 GINS complex protein GBS_Bsp-like PF08481.10 KXX75098.1 - 0.00097 19.2 0.2 0.0026 17.8 0.2 1.6 1 0 0 1 1 1 1 GBS Bsp-like repeat SLATT_4 PF18186.1 KXX75098.1 - 8.9 5.9 8.7 38 3.9 6.6 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Aldolase_II PF00596.21 KXX75099.1 - 8.4e-44 149.7 0.0 9.9e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldedh PF00171.22 KXX75101.1 - 7.6e-135 450.0 0.2 9.1e-135 449.7 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1344 PF07076.11 KXX75101.1 - 0.1 12.6 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Calreticulin PF00262.18 KXX75102.1 - 9.4e-170 564.3 20.1 1.3e-169 563.8 20.1 1.2 1 0 0 1 1 1 1 Calreticulin family DUF1911 PF08929.10 KXX75102.1 - 0.063 14.1 0.1 0.31 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) MOSC PF03473.17 KXX75103.1 - 1.3e-35 122.3 0.0 2.3e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXX75103.1 - 7.6e-22 77.4 0.0 1.3e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KXX75103.1 - 1.7e-21 76.6 0.0 1.7e-20 73.3 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class-V AAA_16 PF13191.6 KXX75104.1 - 2.6e-14 53.9 0.6 1.5e-12 48.2 0.6 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX75104.1 - 4.5e-14 52.9 0.0 1.2e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXX75104.1 - 1.6e-09 38.3 0.0 4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KXX75104.1 - 1.2e-08 34.6 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 KXX75104.1 - 2.1e-06 27.8 0.1 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 AAA lid domain Cdc6_C PF09079.11 KXX75104.1 - 5.7e-05 23.0 0.0 0.00021 21.2 0.0 1.9 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_19 PF13245.6 KXX75104.1 - 0.00088 19.6 0.7 0.003 17.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXX75104.1 - 0.0025 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX75104.1 - 0.0034 17.4 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXX75104.1 - 0.01 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KXX75104.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 KXX75104.1 - 0.011 15.9 0.1 0.032 14.3 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KXX75104.1 - 0.021 14.9 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX75104.1 - 0.023 15.1 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 KXX75104.1 - 0.028 13.5 0.3 0.089 11.8 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 KXX75104.1 - 0.028 13.6 0.0 0.061 12.5 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.15 KXX75104.1 - 0.029 14.3 0.0 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 KXX75104.1 - 0.031 14.2 0.1 0.079 12.9 0.1 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 KXX75104.1 - 0.038 13.9 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KXX75104.1 - 0.081 13.5 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXX75104.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_32 PF13654.6 KXX75104.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 KXX75104.1 - 0.13 11.1 0.0 0.29 9.9 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain NB-ARC PF00931.22 KXX75104.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Fungal_trans PF04082.18 KXX75105.1 - 2.6e-10 39.8 0.0 4.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX75105.1 - 1.1e-08 35.1 8.3 2e-08 34.2 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.6 KXX75106.1 - 9e-15 54.7 1.9 1.1e-13 51.2 0.2 2.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family URO-D PF01208.17 KXX75108.1 - 5.3e-129 430.3 0.0 6e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) FR47 PF08445.10 KXX75109.1 - 0.00055 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF3602 PF12223.8 KXX75110.1 - 9.1e-16 58.2 7.6 2.5e-12 47.2 3.2 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Velvet PF11754.8 KXX75111.1 - 1.6e-94 316.5 0.1 1.6e-94 316.5 0.1 1.7 2 0 0 2 2 2 1 Velvet factor Beta-lactamase PF00144.24 KXX75112.1 - 4.3e-47 161.0 1.6 6e-47 160.5 1.6 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KXX75112.1 - 0.0045 16.5 0.1 0.0099 15.3 0.1 1.5 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KXX75112.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Beta-lactamase enzyme family PH_10 PF15411.6 KXX75114.1 - 3.3e-41 140.4 0.2 6.2e-41 139.5 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KXX75114.1 - 7.4e-34 115.9 0.0 1.5e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KXX75114.1 - 2.6e-21 76.7 0.1 5.4e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KXX75114.1 - 2.7e-10 40.0 0.0 6.5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Snf7 PF03357.21 KXX75119.1 - 7.1e-45 152.7 13.3 8.8e-45 152.4 13.3 1.1 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.6 KXX75119.1 - 0.097 12.4 9.1 0.18 11.5 7.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 KXX75119.1 - 0.12 12.9 6.9 15 6.2 0.0 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.13 KXX75119.1 - 0.12 12.3 1.4 0.26 11.3 0.2 2.1 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain FUSC PF04632.12 KXX75119.1 - 0.26 9.8 3.5 0.83 8.1 0.8 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family FlxA PF14282.6 KXX75119.1 - 0.28 11.2 10.9 0.26 11.3 9.1 1.9 1 1 1 2 2 2 0 FlxA-like protein XhlA PF10779.9 KXX75119.1 - 0.65 10.2 9.7 6.7 7.0 2.0 3.8 2 1 2 4 4 4 0 Haemolysin XhlA FlaC_arch PF05377.11 KXX75119.1 - 0.82 10.1 8.7 5.7 7.4 0.0 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.6 KXX75119.1 - 1.1 9.7 5.6 1.6 9.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) COG2 PF06148.11 KXX75119.1 - 1.3 9.1 5.8 0.76 9.9 2.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mod_r PF07200.13 KXX75119.1 - 1.4 9.0 10.7 1.3 9.1 8.0 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2205 PF10224.9 KXX75119.1 - 1.9 8.6 9.5 1.1 9.2 4.2 3.0 2 1 1 3 3 3 0 Short coiled-coil protein Helo_like_N PF17111.5 KXX75120.1 - 6.3e-14 51.8 0.1 1.7e-13 50.5 0.0 1.7 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXX75120.1 - 0.0001 22.5 0.1 0.0005 20.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_4 PF13637.6 KXX75120.1 - 0.066 13.8 0.1 2 9.1 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX75120.1 - 0.14 12.8 0.0 0.93 10.1 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Uso1_p115_C PF04871.13 KXX75120.1 - 0.76 10.2 7.5 1.6 9.1 6.2 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region WD40 PF00400.32 KXX75121.1 - 6.2e-27 93.3 19.0 3.9e-05 24.3 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KXX75121.1 - 4e-14 52.2 3.4 3.2e-13 49.3 1.3 2.6 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 KXX75121.1 - 2.4e-07 30.5 0.6 1.4e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KXX75121.1 - 4.6e-06 26.8 0.1 2.1 8.7 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX75121.1 - 6.4e-06 25.1 1.2 0.00078 18.2 0.2 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KXX75121.1 - 0.00036 20.0 0.1 0.0022 17.4 0.1 2.2 2 1 0 2 2 2 1 WD40-like domain F-box_4 PF15966.5 KXX75121.1 - 0.06 13.2 0.1 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 F-box MgtE_N PF03448.17 KXX75121.1 - 0.071 13.7 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain NmrA PF05368.13 KXX75122.1 - 1.3e-34 119.8 0.0 1.6e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX75122.1 - 2.9e-16 59.9 0.0 3.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX75122.1 - 0.00038 20.0 0.1 0.00081 18.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXX75122.1 - 0.0082 16.6 0.1 0.015 15.7 0.1 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain His_biosynth PF00977.21 KXX75122.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXX75122.1 - 0.034 14.4 0.0 0.062 13.6 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain BUD22 PF09073.10 KXX75123.1 - 0.47 9.7 8.0 0.52 9.6 8.0 1.1 1 0 0 1 1 1 0 BUD22 CCDC53 PF10152.9 KXX75124.1 - 2.3 8.7 4.6 28 5.1 0.9 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Fungal_trans PF04082.18 KXX75125.1 - 7.7e-67 225.1 0.1 1e-66 224.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXX75125.1 - 3.5e-06 27.2 9.1 0.00037 20.8 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX75125.1 - 0.0071 17.1 7.4 0.15 13.0 0.8 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KXX75125.1 - 0.85 9.7 2.3 1.7 8.8 2.3 1.5 1 1 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KXX75125.1 - 7 7.3 10.6 2.3 8.8 0.7 3.2 3 0 0 3 3 3 0 Zinc-finger double domain SAP30_Sin3_bdg PF13867.6 KXX75126.1 - 1.6e-08 34.8 0.7 9.8e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ribosomal_60s PF00428.19 KXX75127.1 - 0.00017 22.1 21.5 0.005 17.4 5.9 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein RXT2_N PF08595.11 KXX75127.1 - 0.0017 18.4 6.3 0.34 10.9 1.2 2.4 2 0 0 2 2 2 2 RXT2-like, N-terminal F-box PF00646.33 KXX75127.1 - 0.0019 18.0 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain NOA36 PF06524.12 KXX75127.1 - 0.0057 16.0 2.0 0.0057 16.0 2.0 2.7 3 0 0 3 3 3 2 NOA36 protein YL1 PF05764.13 KXX75127.1 - 0.0068 16.6 10.3 0.015 15.4 10.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Pox_Ag35 PF03286.14 KXX75127.1 - 0.0075 16.1 8.0 0.25 11.1 0.3 2.3 2 0 0 2 2 2 2 Pox virus Ag35 surface protein Spt5_N PF11942.8 KXX75127.1 - 0.035 15.1 0.7 0.035 15.1 0.7 3.1 3 0 0 3 3 2 0 Spt5 transcription elongation factor, acidic N-terminal FAM176 PF14851.6 KXX75127.1 - 0.1 12.3 11.5 2.5 7.8 5.7 2.4 2 0 0 2 2 2 0 FAM176 family RNase_H2_suC PF08615.11 KXX75127.1 - 0.12 12.6 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PTPRCAP PF15713.5 KXX75127.1 - 0.31 11.3 11.2 0.39 11.0 3.5 2.7 3 0 0 3 3 2 0 Protein tyrosine phosphatase receptor type C-associated Cnd2 PF05786.14 KXX75127.1 - 0.34 9.5 12.4 0.1 11.3 3.4 2.1 2 0 0 2 2 2 0 Condensin complex subunit 2 Sigma70_ner PF04546.13 KXX75127.1 - 0.34 10.8 14.6 1.1 9.1 1.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF1840 PF08895.11 KXX75127.1 - 0.43 10.9 5.8 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) NESP55 PF06390.12 KXX75127.1 - 0.55 9.8 11.7 0.21 11.2 5.6 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF3246 PF11596.8 KXX75127.1 - 0.99 8.8 12.2 0.025 14.0 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) GCIP PF13324.6 KXX75127.1 - 1.5 8.3 5.5 8.6 5.9 0.3 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting THOC2_N PF16134.5 KXX75127.1 - 1.6 7.3 3.6 14 4.2 0.1 2.0 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus DUF3245 PF11595.8 KXX75127.1 - 1.9 8.9 10.4 4.7 7.7 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) BUD22 PF09073.10 KXX75127.1 - 2.9 7.1 15.3 0.11 11.8 8.1 1.9 2 0 0 2 2 2 0 BUD22 TFB6 PF17110.5 KXX75127.1 - 3.8 7.2 5.5 4.8 6.9 0.5 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TLP-20 PF06088.11 KXX75127.1 - 4.1 7.3 7.6 8.4 6.2 0.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PGA2 PF07543.12 KXX75127.1 - 5.1 7.1 12.0 1.5 8.8 4.2 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 CDC45 PF02724.14 KXX75127.1 - 6.8 4.9 13.1 0.33 9.2 2.8 2.1 2 0 0 2 2 2 0 CDC45-like protein MFS_1 PF07690.16 KXX75128.1 - 1.8e-36 125.8 57.0 3.4e-36 124.9 53.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX75128.1 - 2e-12 46.7 6.3 2e-12 46.7 6.3 3.6 4 1 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 KXX75128.1 - 1.6e-09 36.8 19.2 5.5e-09 35.0 19.2 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DnaJ_C PF01556.18 KXX75129.1 - 1.7e-37 128.8 0.0 2.2e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXX75129.1 - 4.7e-24 84.3 1.3 8.4e-24 83.5 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXX75129.1 - 1.9e-09 37.7 19.4 3.8e-09 36.8 19.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXX75129.1 - 0.029 14.3 12.2 0.41 10.6 1.9 2.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2318 PF10080.9 KXX75129.1 - 0.95 9.6 4.0 0.52 10.5 1.7 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) HypA PF01155.19 KXX75129.1 - 8.1 6.5 8.1 85 3.2 7.7 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2418 PF10332.9 KXX75130.1 - 8.5e-35 119.2 0.4 1.7e-34 118.2 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Pyridox_oxase_2 PF12766.7 KXX75131.1 - 4.3e-19 69.0 0.0 7.5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase E1_DerP2_DerF2 PF02221.15 KXX75132.1 - 1.2e-29 103.4 0.7 1.4e-29 103.2 0.7 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KXX75132.1 - 0.00089 19.6 0.0 0.0018 18.6 0.0 1.5 1 1 0 1 1 1 1 ML-like domain Alph_Pro_TM PF09608.10 KXX75132.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) ATP-synt_F PF01990.17 KXX75133.1 - 1.7e-29 102.0 0.0 2e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit SWIRM-assoc_3 PF16498.5 KXX75133.1 - 0.05 13.8 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal ABC_tran_CTD PF16326.5 KXX75134.1 - 2e-05 24.7 4.6 2e-05 24.7 4.6 5.9 4 2 2 6 6 6 1 ABC transporter C-terminal domain FapA PF03961.13 KXX75134.1 - 0.00073 18.3 9.8 0.00073 18.3 9.8 3.7 2 1 1 3 3 3 1 Flagellar Assembly Protein A DUF4407 PF14362.6 KXX75134.1 - 1.9 7.7 51.5 1.1 8.5 20.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Hemagglutinin PF00509.18 KXX75134.1 - 2.1 6.7 6.1 0.21 10.0 1.2 1.7 2 0 0 2 2 2 0 Haemagglutinin Claudin_3 PF06653.11 KXX75136.1 - 0.31 11.0 3.4 3.2 7.7 0.2 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like RNA_pol_Rpb5_C PF01191.19 KXX75137.1 - 1.1e-33 114.9 0.8 2.3e-33 113.9 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KXX75137.1 - 5.3e-29 100.6 0.0 8.3e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KXX75137.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease AAA_3 PF07726.11 KXX75137.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SET PF00856.28 KXX75138.1 - 7.3e-08 33.0 0.0 2.1e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 SET domain PHD PF00628.29 KXX75138.1 - 3.8e-07 29.9 8.5 7.2e-07 29.0 8.5 1.5 1 0 0 1 1 1 1 PHD-finger Titin_Z PF09042.11 KXX75138.1 - 0.03 14.3 0.3 0.1 12.6 0.3 1.9 1 0 0 1 1 1 0 Titin Z Fungal_trans PF04082.18 KXX75139.1 - 1.9e-16 59.9 0.0 3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX75139.1 - 7.5e-09 35.6 11.3 1.3e-08 34.9 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2190 PF09956.9 KXX75141.1 - 0.068 13.7 0.1 0.075 13.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) Cytochrom_B_N_2 PF13631.6 KXX75141.1 - 0.082 12.9 0.1 0.095 12.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Beta-lactamase PF00144.24 KXX75141.1 - 0.11 11.7 0.4 0.16 11.2 0.2 1.3 1 1 0 1 1 1 0 Beta-lactamase Chorismate_synt PF01264.21 KXX75142.1 - 9.1e-140 465.0 0.0 1.1e-139 464.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase AA_permease_2 PF13520.6 KXX75143.1 - 4.8e-42 144.3 27.0 2.7e-41 141.8 27.0 1.9 1 1 0 1 1 1 1 Amino acid permease DUF2130 PF09903.9 KXX75144.1 - 0.0073 15.6 0.3 0.011 15.0 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) LAT2 PF15703.5 KXX75144.1 - 0.052 13.4 0.2 0.12 12.2 0.2 1.6 2 0 0 2 2 2 0 Linker for activation of T-cells family member 2 MazG-like PF12643.7 KXX75145.1 - 4.5e-21 74.9 0.0 6.8e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 KXX75145.1 - 2.8e-06 27.4 0.0 4.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF550 PF04447.12 KXX75145.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF550) Ank_2 PF12796.7 KXX75146.1 - 9.3e-111 362.6 16.8 2.7e-17 63.1 0.3 6.8 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX75146.1 - 7.4e-75 246.4 10.7 2.1e-09 37.7 0.0 9.2 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75146.1 - 9.2e-59 188.5 0.9 4.7e-05 23.5 0.0 13.1 13 0 0 13 13 13 12 Ankyrin repeat Ank PF00023.30 KXX75146.1 - 3e-56 185.5 11.0 2.4e-06 27.7 0.0 12.4 12 0 0 12 12 12 12 Ankyrin repeat Ank_5 PF13857.6 KXX75146.1 - 3.6e-51 170.5 8.2 1.1e-06 28.8 0.1 10.5 2 2 9 11 11 11 10 Ankyrin repeats (many copies) EccE PF11203.8 KXX75146.1 - 0.012 16.0 0.4 1.1 9.7 0.0 3.0 2 1 1 3 3 3 0 Putative type VII ESX secretion system translocon, EccE DUF1843 PF08898.10 KXX75146.1 - 0.049 14.1 1.1 20 5.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) HATPase_c_3 PF13589.6 KXX75147.1 - 5.8e-18 65.0 0.0 1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KXX75147.1 - 1.1e-07 31.7 0.0 2.4e-06 27.4 0.0 2.8 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KXX75147.1 - 0.012 16.1 0.0 0.037 14.5 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Clathrin PF00637.20 KXX75148.1 - 1.2e-25 90.1 2.3 2.3e-23 82.6 1.7 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 KXX75148.1 - 1.2e-20 73.4 0.2 3.4e-20 72.0 0.2 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.6 KXX75148.1 - 1.1e-06 28.4 6.2 2.7e-06 27.1 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KXX75148.1 - 1.2e-06 28.4 4.0 3.5e-06 26.9 4.0 1.8 1 1 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 KXX75148.1 - 4.3e-05 23.4 5.8 8.6e-05 22.4 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXX75148.1 - 5.6e-05 23.3 4.1 0.00012 22.3 4.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXX75148.1 - 0.00028 21.1 4.9 0.00028 21.1 4.9 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX75148.1 - 0.00064 19.5 4.5 0.0014 18.4 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 KXX75148.1 - 0.00066 19.3 0.4 0.00066 19.3 0.4 2.1 2 0 0 2 2 1 1 TPR repeat TPR_14 PF13428.6 KXX75148.1 - 0.0024 18.5 0.4 2.2 9.3 0.0 3.8 3 1 0 3 3 2 1 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 KXX75148.1 - 0.0026 17.8 1.2 0.007 16.4 1.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KXX75148.1 - 0.0045 16.8 1.6 0.011 15.5 1.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KXX75148.1 - 0.017 15.0 0.4 0.041 13.7 0.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TPR_2 PF07719.17 KXX75148.1 - 0.029 14.5 2.0 0.096 12.9 0.1 2.9 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_15 PF13429.6 KXX75148.1 - 0.035 13.3 1.3 0.32 10.2 1.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4810 PF16068.5 KXX75148.1 - 0.065 13.8 2.1 17 6.0 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) zf-RING_UBOX PF13445.6 KXX75148.1 - 0.086 12.9 6.3 0.23 11.5 6.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger TPR_10 PF13374.6 KXX75148.1 - 0.17 11.8 0.3 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat eIF3_N PF09440.10 KXX75148.1 - 0.34 11.3 3.3 0.39 11.1 1.2 2.2 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain zf-RING-like PF08746.11 KXX75148.1 - 0.45 10.9 4.5 1.2 9.5 4.5 1.8 1 0 0 1 1 1 0 RING-like domain ANAPC3 PF12895.7 KXX75148.1 - 0.71 10.1 8.0 15 5.9 0.4 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C3HC4_3 PF13920.6 KXX75148.1 - 1.9 8.4 3.9 4.2 7.3 3.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXX75148.1 - 2.5 8.3 4.5 5.2 7.3 4.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXX75148.1 - 3.5 7.3 10.0 1.6 8.4 3.9 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type TPR_1 PF00515.28 KXX75148.1 - 3.6 7.6 6.0 1.7 8.6 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 KXX75148.1 - 4 7.3 5.0 11 5.9 5.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger TPR_12 PF13424.6 KXX75148.1 - 4.9 7.5 5.5 2.8 8.3 0.1 3.0 3 1 0 3 3 2 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.19 KXX75149.1 - 2.8e-06 27.3 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HET PF06985.11 KXX75150.1 - 0.086 13.2 0.9 0.18 12.1 0.9 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) AAA PF00004.29 KXX75151.1 - 2.3e-36 125.1 0.0 5e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX75151.1 - 1.3e-07 31.3 0.0 7e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KXX75151.1 - 1.7e-07 31.8 0.1 6.1e-06 26.7 0.2 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX75151.1 - 3.7e-05 24.0 0.1 0.0024 18.1 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXX75151.1 - 0.00097 19.3 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX75151.1 - 0.0022 18.0 0.1 0.0058 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXX75151.1 - 0.0023 17.7 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KXX75151.1 - 0.0066 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 KXX75151.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KXX75151.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXX75151.1 - 0.012 15.1 0.0 0.053 13.0 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXX75151.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DTHCT PF08070.11 KXX75151.1 - 0.021 15.5 0.4 0.039 14.7 0.4 1.4 1 0 0 1 1 1 0 DTHCT (NUC029) region AAA_30 PF13604.6 KXX75151.1 - 0.022 14.5 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 KXX75151.1 - 0.023 13.3 0.0 0.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) TsaE PF02367.17 KXX75151.1 - 0.028 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KXX75151.1 - 0.031 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXX75151.1 - 0.04 13.3 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXX75151.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KXX75151.1 - 0.066 12.9 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXX75151.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXX75151.1 - 0.084 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 KXX75151.1 - 0.14 11.3 0.3 0.29 10.3 0.1 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain MCM PF00493.23 KXX75151.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain Glyco_hydro_63 PF03200.16 KXX75152.1 - 1.1e-178 595.0 1.2 7.3e-177 589.0 0.0 2.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KXX75152.1 - 2.5e-82 276.4 0.8 4.7e-82 275.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KXX75152.1 - 0.0081 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 KXX75152.1 - 0.14 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase bZIP_2 PF07716.15 KXX75153.1 - 0.025 14.7 9.4 0.025 14.7 9.4 1.6 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 KXX75153.1 - 0.76 9.9 9.7 1.5 9.0 9.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor CDC45 PF02724.14 KXX75153.1 - 1 7.5 15.5 1.3 7.2 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 KXX75153.1 - 1.5 7.2 5.5 1.9 6.9 5.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 KXX75153.1 - 5.1 5.8 9.1 5.8 5.6 9.1 1.1 1 0 0 1 1 1 0 Presenilin IGR PF09597.10 KXX75154.1 - 3.8e-25 87.7 0.4 6.3e-25 87.0 0.4 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.30 KXX75154.1 - 0.0043 17.5 0.0 0.067 13.6 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SNF2_N PF00176.23 KXX75155.1 - 5.2e-59 199.7 0.0 8.4e-59 199.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 KXX75155.1 - 2.8e-09 37.1 10.6 5.7e-09 36.2 10.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX75155.1 - 1.8e-08 34.0 9.5 4.1e-08 32.9 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX75155.1 - 2e-08 34.0 9.6 4.1e-08 33.0 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX75155.1 - 1.1e-07 31.6 8.9 2.2e-07 30.6 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX75155.1 - 1e-05 25.7 7.2 3.2e-05 24.1 7.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 KXX75155.1 - 2e-05 24.9 0.0 4.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KXX75155.1 - 3.9e-05 23.5 9.5 8.1e-05 22.5 9.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXX75155.1 - 4.7e-05 23.3 6.7 0.00022 21.2 7.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXX75155.1 - 0.00029 20.6 11.2 0.00059 19.7 11.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KXX75155.1 - 0.018 15.0 1.6 0.04 13.9 1.6 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 KXX75155.1 - 0.072 13.3 8.2 0.18 11.9 8.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glu-tRNAGln PF02686.15 KXX75155.1 - 0.084 13.2 0.2 1.1 9.7 0.8 2.6 2 0 0 2 2 1 0 Glu-tRNAGln amidotransferase C subunit DUF1759 PF03564.15 KXX75155.1 - 0.17 11.8 1.7 0.92 9.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) CemA PF03040.14 KXX75155.1 - 0.27 11.1 2.4 1.6 8.6 0.0 2.5 1 1 0 2 2 2 0 CemA family FYVE PF01363.21 KXX75155.1 - 0.34 11.1 3.7 1.2 9.3 3.7 1.9 1 0 0 1 1 1 0 FYVE zinc finger zf-P11 PF03854.14 KXX75155.1 - 0.8 9.4 7.1 2.8 7.7 7.1 1.9 1 1 1 2 2 2 0 P-11 zinc finger DZR PF12773.7 KXX75155.1 - 1.6 8.8 5.6 4.9 7.3 5.6 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 KXX75155.1 - 1.8 8.8 5.9 6.8 6.9 5.9 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXX75155.1 - 2.5 7.9 8.4 1.4 8.7 5.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXX75155.1 - 3.2 7.9 5.8 7.2 6.7 5.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sec10 PF07393.11 KXX75156.1 - 1.1e-176 589.3 0.0 1.4e-176 589.0 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KXX75156.1 - 8.2e-08 32.0 0.3 4.3e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXX75156.1 - 3.2e-06 26.9 0.0 7.7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXX75156.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box MSA-2c PF12238.8 KXX75156.1 - 0.64 10.0 6.9 0.61 10.0 1.5 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c Pkinase PF00069.25 KXX75157.1 - 1e-61 208.7 0.0 2e-61 207.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75157.1 - 1.9e-30 106.1 0.0 2.8e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX75157.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXX75157.1 - 0.2 10.4 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Frag1 PF10277.9 KXX75158.1 - 2.8e-43 148.0 13.9 3.3e-43 147.8 13.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KXX75158.1 - 0.022 14.4 16.3 0.072 12.7 15.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF2070 PF09843.9 KXX75158.1 - 3.4 5.8 10.6 4.3 5.5 10.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4064 PF13273.6 KXX75158.1 - 7.1 7.0 11.9 63 3.9 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) EMP70 PF02990.16 KXX75158.1 - 8.8 4.9 10.7 17 4.0 10.7 1.5 1 1 0 1 1 1 0 Endomembrane protein 70 Eisosome1 PF12757.7 KXX75159.1 - 3e-40 137.4 17.4 3e-40 137.4 17.4 3.6 3 0 0 3 3 3 1 Eisosome protein 1 Ribosomal_L4 PF00573.22 KXX75160.1 - 8.8e-39 133.2 0.9 1.2e-38 132.8 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KXX75160.1 - 1.2e-28 99.0 0.5 1.2e-28 99.0 0.5 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_28 PF00295.17 KXX75161.1 - 4.9e-42 144.1 7.1 6.7e-42 143.7 7.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RabGAP-TBC PF00566.18 KXX75162.1 - 9.1e-35 120.3 5.7 3.1e-34 118.5 5.7 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KXX75162.1 - 7.3e-07 28.8 0.0 5.3e-05 22.8 0.0 3.0 2 1 0 2 2 2 1 Rab-binding domain (RBD) Pkinase PF00069.25 KXX75164.1 - 1.1e-63 215.1 0.0 1.3e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75164.1 - 8e-34 117.1 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX75164.1 - 1.3e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXX75164.1 - 0.00012 21.0 0.0 0.00017 20.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KXX75164.1 - 0.0054 16.4 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXX75164.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KXX75164.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Amidohydro_2 PF04909.14 KXX75165.1 - 1.9e-19 70.6 0.1 3.9e-19 69.5 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase DEAD PF00270.29 KXX75166.1 - 1.5e-41 142.1 0.0 2.8e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX75166.1 - 3.3e-30 104.7 0.0 7.2e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX75166.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXX75166.1 - 0.017 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain BAF1_ABF1 PF04684.13 KXX75166.1 - 0.13 11.2 0.6 0.18 10.8 0.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FA_hydroxylase PF04116.13 KXX75167.1 - 2.9e-21 76.2 14.3 2.9e-21 76.2 14.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Dor1 PF04124.12 KXX75167.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family DUF4519 PF15012.6 KXX75167.1 - 0.24 11.6 1.3 0.63 10.2 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Septin PF00735.18 KXX75169.1 - 3.8e-16 59.2 0.0 2e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 KXX75169.1 - 9.9e-05 22.4 0.0 0.0007 19.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX75169.1 - 0.00081 19.3 0.1 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 KXX75169.1 - 0.0045 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KXX75169.1 - 0.0065 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KXX75169.1 - 0.0067 16.8 0.4 0.025 15.0 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KXX75169.1 - 0.026 14.3 0.2 0.096 12.4 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 KXX75169.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 KXX75169.1 - 0.037 14.5 0.1 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 KXX75169.1 - 0.046 13.7 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KXX75169.1 - 0.049 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KXX75169.1 - 0.055 12.6 0.4 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KXX75169.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KXX75169.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXX75169.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX75169.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXX75169.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 KXX75169.1 - 0.18 12.1 0.1 0.33 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXX75169.1 - 0.21 10.9 0.1 0.37 10.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin zf-C3HC4_3 PF13920.6 KXX75170.1 - 0.002 17.9 11.0 0.0031 17.3 11.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXX75170.1 - 0.33 10.9 6.1 0.54 10.2 6.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KXX75170.1 - 8.1 6.5 12.6 13 5.8 12.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain NACHT_sigma PF17106.5 KXX75171.1 - 0.00013 22.0 1.3 0.00027 21.0 1.3 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases PPR_2 PF13041.6 KXX75172.1 - 1.1e-30 105.5 0.0 3e-08 33.7 0.0 7.3 6 1 1 7 7 7 6 PPR repeat family PPR_3 PF13812.6 KXX75172.1 - 3.2e-19 68.8 0.0 1.8e-06 27.9 0.0 5.7 4 2 3 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 KXX75172.1 - 2.9e-17 61.6 0.0 0.02 15.1 0.0 6.4 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.7 KXX75172.1 - 1.6e-11 43.7 0.1 0.052 13.3 0.0 5.5 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 KXX75172.1 - 4.3e-08 32.8 0.0 0.0011 18.4 0.0 3.4 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP CCDC24 PF15669.5 KXX75172.1 - 0.029 14.3 0.0 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family SesA PF17107.5 KXX75173.1 - 1.9e-23 83.0 0.0 8e-23 80.9 0.1 2.0 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 KXX75173.1 - 5.8e-19 68.0 15.8 8.5e-19 67.4 15.8 1.3 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases DAGK_cat PF00781.24 KXX75173.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.9 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain DnaJ PF00226.31 KXX75174.1 - 2.1e-11 43.7 0.2 6.3e-11 42.2 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Golgin_A5 PF09787.9 KXX75174.1 - 3.1 7.2 14.6 0.095 12.2 4.5 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 DIOX_N PF14226.6 KXX75175.1 - 3.5e-23 82.6 0.0 6.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXX75175.1 - 3.9e-17 62.6 0.0 6.5e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YL1 PF05764.13 KXX75176.1 - 0.021 14.9 22.9 0.062 13.4 3.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein SDA1 PF05285.12 KXX75176.1 - 0.32 10.4 12.0 0.47 9.8 12.0 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXX75176.1 - 0.56 9.5 14.3 0.69 9.2 14.3 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KXX75176.1 - 2.4 6.1 18.6 3 5.9 18.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi GCV_T PF01571.21 KXX75177.1 - 1.6e-07 30.9 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF4381 PF14316.6 KXX75181.1 - 0.025 14.8 0.2 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) NiFe_hyd_3_EhaA PF17367.2 KXX75181.1 - 0.18 11.9 0.1 0.18 11.9 0.1 1.6 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A dCMP_cyt_deam_1 PF00383.23 KXX75182.1 - 1.5e-09 37.6 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXX75182.1 - 3.8e-07 29.9 0.0 5.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXX75182.1 - 0.1 12.7 0.5 2.1 8.4 0.5 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase TB2_DP1_HVA22 PF03134.19 KXX75183.1 - 1.2e-26 92.5 8.9 1.8e-26 91.8 8.9 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4799 PF16056.5 KXX75183.1 - 0.0049 16.1 0.3 0.0075 15.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4799) RSRP PF17069.5 KXX75183.1 - 0.14 11.7 13.6 0.21 11.1 13.6 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 AC_N PF16214.5 KXX75183.1 - 5.9 5.9 6.6 8.5 5.4 6.6 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Mgm101p PF06420.12 KXX75184.1 - 1.2e-87 291.8 0.0 1.5e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.9 KXX75185.1 - 9.5e-145 482.4 0.0 1.2e-144 482.1 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KXX75185.1 - 2.5e-22 79.2 0.0 4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KXX75185.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Toxin_35 PF10530.9 KXX75188.1 - 0.0006 19.7 6.0 0.00073 19.5 6.0 1.2 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Conotoxin PF02950.17 KXX75188.1 - 0.001 20.1 0.8 0.0011 19.9 0.8 1.3 1 0 0 1 1 1 1 Conotoxin Omega-toxin PF06357.11 KXX75188.1 - 0.049 13.4 5.2 0.069 13.0 5.2 1.3 1 0 0 1 1 1 0 Omega-atracotoxin Prefoldin_2 PF01920.20 KXX75189.1 - 9.4e-21 73.8 0.4 1.1e-20 73.5 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Uso1_p115_C PF04871.13 KXX75189.1 - 0.098 13.0 2.4 6.1 7.2 0.1 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SKA2 PF16740.5 KXX75189.1 - 0.1 12.4 3.7 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF16 PF01519.16 KXX75189.1 - 0.77 10.3 4.3 2.6 8.6 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KXX75189.1 - 1.5 9.3 3.9 1.1 9.7 0.7 2.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Swi5 PF07061.11 KXX75189.1 - 1.9 8.7 7.4 0.6 10.2 1.3 2.1 2 0 0 2 2 2 0 Swi5 DUF4349 PF14257.6 KXX75189.1 - 4.9 6.6 6.9 19 4.6 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Ank_5 PF13857.6 KXX75190.1 - 2.3e-36 123.4 4.8 7.2e-10 38.9 0.1 5.2 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX75190.1 - 5.6e-33 113.4 0.7 1.7e-11 44.5 0.7 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX75190.1 - 7.2e-33 112.5 3.0 2.1e-10 40.9 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75190.1 - 1.7e-30 101.6 1.3 5.9e-05 23.2 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXX75190.1 - 4.6e-30 102.7 7.2 6.7e-06 26.3 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Phage_tail_X PF05489.12 KXX75190.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X DUF2767 PF10965.8 KXX75190.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) WD40 PF00400.32 KXX75191.1 - 3.2e-43 144.9 17.6 7.9e-09 36.0 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX75191.1 - 0.00026 21.2 0.3 3 8.2 0.0 4.3 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX75191.1 - 0.1 11.2 2.3 27 3.2 0.0 3.6 1 1 1 4 4 4 0 Nucleoporin Nup120/160 Ceramidase PF05875.12 KXX75192.1 - 4.7e-91 304.8 16.0 5.5e-91 304.7 16.0 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_U4 PF03419.13 KXX75192.1 - 0.77 9.0 10.3 0.081 12.2 5.7 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA TMF_TATA_bd PF12325.8 KXX75193.1 - 5.8e-40 136.1 8.9 5.8e-40 136.1 8.9 6.6 2 1 4 6 6 6 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXX75193.1 - 1.8e-19 69.5 16.2 1.8e-19 69.5 16.2 8.4 4 3 4 8 8 8 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KXX75193.1 - 0.00019 21.7 4.6 0.00019 21.7 4.6 6.5 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) BRE1 PF08647.11 KXX75193.1 - 0.0026 17.8 0.8 0.0026 17.8 0.8 7.0 2 1 3 6 6 4 1 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.7 KXX75193.1 - 0.0041 17.3 18.0 0.0041 17.3 18.0 5.1 3 1 2 5 5 5 1 Tropomyosin like GAS PF13851.6 KXX75193.1 - 0.0046 16.3 16.8 0.0046 16.3 16.8 5.0 2 1 3 5 5 5 2 Growth-arrest specific micro-tubule binding DUF4803 PF16061.5 KXX75193.1 - 0.086 12.3 3.1 0.19 11.1 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) DUF4763 PF15960.5 KXX75193.1 - 0.29 10.4 0.0 0.29 10.4 0.0 4.8 2 1 1 4 4 4 0 Domain of unknown function (DUF4763) WD40_alt PF14077.6 KXX75193.1 - 4.5 7.2 6.5 1.4 8.8 0.9 3.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif SelK_SelG PF10961.8 KXX75193.1 - 8.3 7.1 7.0 20 5.9 7.0 1.6 1 0 0 1 1 1 0 Selenoprotein SelK_SelG DUF948 PF06103.11 KXX75193.1 - 9.7 6.5 31.9 1.7 9.0 4.1 6.8 3 2 0 5 5 5 0 Bacterial protein of unknown function (DUF948) AAA PF00004.29 KXX75194.1 - 1.6e-15 57.7 0.0 2.8e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KXX75194.1 - 1.4e-10 41.2 2.4 1.5e-10 41.1 0.2 2.1 3 0 0 3 3 3 1 AAA lid domain AAA_16 PF13191.6 KXX75194.1 - 7e-10 39.5 1.5 3.7e-09 37.2 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX75194.1 - 4e-09 36.9 0.0 1.3e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXX75194.1 - 0.001 19.4 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXX75194.1 - 0.0057 16.9 0.0 0.12 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXX75194.1 - 0.021 14.6 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXX75194.1 - 0.032 14.8 0.0 0.07 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ssDBP PF17878.1 KXX75194.1 - 0.049 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Single-stranded DNA-binding protein TPR_MalT PF17874.1 KXX75194.1 - 0.056 12.8 0.3 0.099 12.0 0.3 1.3 1 0 0 1 1 1 0 MalT-like TPR region AAA_33 PF13671.6 KXX75194.1 - 0.056 13.6 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.6 KXX75194.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXX75194.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KXX75194.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.1 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea RPN6_N PF18055.1 KXX75195.1 - 7.1e-48 161.8 3.7 7.7e-48 161.7 0.5 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KXX75195.1 - 5.9e-21 74.9 0.9 1.9e-20 73.3 0.2 2.3 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 KXX75195.1 - 5.6e-11 42.0 0.8 1.3e-10 40.8 0.8 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KXX75195.1 - 0.00014 21.6 6.1 1.2 9.3 1.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX75195.1 - 0.00029 20.3 2.4 0.00029 20.3 2.4 2.4 2 2 0 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 KXX75195.1 - 0.00039 20.1 0.3 0.00039 20.1 0.3 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_2 PF07719.17 KXX75195.1 - 0.0018 18.2 6.0 9.4 6.6 0.0 5.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX75195.1 - 0.002 18.4 22.2 0.27 11.6 2.3 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX75195.1 - 0.036 13.9 7.3 8.6 6.4 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KXX75195.1 - 0.048 13.7 0.1 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 KXX75195.1 - 0.063 13.4 0.1 0.32 11.2 0.0 2.2 3 0 0 3 3 2 0 DprA winged helix domain DUF87 PF01935.17 KXX75195.1 - 0.22 11.6 1.5 0.93 9.5 0.2 2.2 2 1 0 2 2 2 0 Helicase HerA, central domain TPR_10 PF13374.6 KXX75195.1 - 0.27 11.2 8.4 65 3.6 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX75195.1 - 0.29 12.1 13.7 40 5.4 0.1 6.5 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXX75195.1 - 0.58 10.9 0.1 0.58 10.9 0.1 3.8 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX75195.1 - 2 8.8 13.4 21 5.7 0.0 6.0 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF4398 PF14346.6 KXX75195.1 - 4.2 8.1 15.4 0.071 13.7 1.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) AT_hook PF02178.19 KXX75196.1 - 0.012 15.4 19.0 0.63 10.1 4.5 3.5 2 0 0 2 2 2 0 AT hook motif OSCP PF00213.18 KXX75198.1 - 2.9e-47 161.0 0.7 3.4e-47 160.8 0.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.17 KXX75198.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 Sds3 PF08598.11 KXX75199.1 - 2.8e-22 79.8 3.3 4.2e-22 79.2 3.3 1.3 1 0 0 1 1 1 1 Sds3-like DUF743 PF05332.11 KXX75199.1 - 9.8 6.3 9.3 0.095 12.8 0.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF743) LSM PF01423.22 KXX75200.1 - 4.9e-15 55.0 0.0 9.9e-15 54.0 0.0 1.5 2 0 0 2 2 2 1 LSM domain Flexi_CP_N PF08358.10 KXX75201.1 - 0.023 14.7 0.1 0.063 13.3 0.1 1.7 1 0 0 1 1 1 0 Carlavirus coat Mob1_phocein PF03637.17 KXX75202.1 - 3.3e-70 235.5 0.0 4.3e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_63 PF03200.16 KXX75203.1 - 1.4e-08 33.9 5.9 5.8e-06 25.3 0.1 3.6 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain PP2C PF00481.21 KXX75204.1 - 6.2e-44 150.6 0.0 9.3e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXX75204.1 - 0.0017 18.0 0.3 0.0061 16.2 0.3 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXX75204.1 - 0.011 15.7 0.2 0.91 9.4 0.0 2.6 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Sof1 PF04158.14 KXX75205.1 - 7.5e-32 109.5 15.6 1.3e-31 108.6 15.6 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KXX75205.1 - 5.9e-25 87.1 12.3 1.5e-06 28.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX75205.1 - 9.6e-09 35.4 0.4 0.11 12.8 0.0 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KXX75205.1 - 2.4e-05 24.3 0.5 0.17 11.9 0.0 4.7 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 KXX75205.1 - 0.017 15.6 1.4 10 6.8 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain Cytochrom_D1 PF02239.16 KXX75205.1 - 0.021 13.4 0.3 0.088 11.3 0.1 2.1 2 1 1 3 3 3 0 Cytochrome D1 heme domain AAA PF00004.29 KXX75207.1 - 6.8e-07 29.8 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KXX75207.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zot PF05707.12 KXX75207.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Histone PF00125.24 KXX75208.1 - 4.3e-40 137.1 0.1 4.8e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXX75208.1 - 0.00023 21.3 0.0 0.00036 20.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXX75208.1 - 0.00094 19.5 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KXX75208.1 - 0.064 13.5 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HLH PF00010.26 KXX75209.1 - 3.7e-12 46.0 0.0 6.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PMBR PF09373.10 KXX75209.1 - 0.58 10.4 1.5 3.4 8.0 0.1 2.6 3 0 0 3 3 3 0 Pseudomurein-binding repeat TPR_10 PF13374.6 KXX75210.1 - 1.6e-73 240.8 0.1 7e-13 48.0 0.0 7.5 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 KXX75210.1 - 8.2e-62 205.5 0.6 1.5e-13 50.9 0.0 6.4 1 1 5 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXX75210.1 - 5.8e-18 63.5 0.9 0.042 13.9 0.0 7.0 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXX75210.1 - 8.3e-18 63.0 2.4 0.055 13.6 0.0 6.8 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXX75210.1 - 2.7e-15 56.7 0.3 0.041 14.5 0.0 6.5 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_4 PF07721.14 KXX75210.1 - 1.9e-12 46.5 1.9 0.22 12.2 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX75210.1 - 4.7e-11 42.0 0.8 0.5 10.3 0.0 6.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX75210.1 - 7.9e-11 41.9 4.4 1.6e-06 27.7 4.0 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KXX75210.1 - 1.3e-08 35.2 0.6 0.31 11.6 0.0 5.7 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXX75210.1 - 6.1e-07 29.7 2.5 3.8 8.6 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX75210.1 - 7.1e-06 25.8 0.9 2.5 8.5 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX75210.1 - 4.6e-05 23.6 1.1 0.57 10.5 0.0 4.8 3 1 3 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXX75210.1 - 0.00046 20.6 8.0 35 5.3 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXX75210.1 - 0.00061 20.0 1.5 19 5.9 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat HemY_N PF07219.13 KXX75210.1 - 0.0013 18.9 1.6 22 5.3 0.0 4.9 5 0 0 5 5 5 0 HemY protein N-terminus PPR PF01535.20 KXX75210.1 - 0.0044 17.2 3.1 28 5.3 0.0 5.8 6 1 1 7 7 6 0 PPR repeat Wzy_C_2 PF11846.8 KXX75210.1 - 0.14 12.1 1.8 39 4.1 0.0 3.6 2 1 2 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal DUF5074 PF16819.5 KXX75210.1 - 0.17 11.9 0.3 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) DUF1923 PF09083.10 KXX75210.1 - 1.3 8.8 7.6 65 3.3 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1923) TPR_10 PF13374.6 KXX75211.1 - 1e-41 139.7 0.1 8.3e-12 44.6 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXX75211.1 - 1.3e-37 127.9 0.2 1.9e-15 56.9 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX75211.1 - 1.1e-11 43.9 0.6 0.011 15.7 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX75211.1 - 5.4e-09 35.5 2.1 2.2 8.6 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXX75211.1 - 1.9e-08 33.7 2.0 1.5 8.8 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_4 PF07721.14 KXX75211.1 - 2.6e-07 30.6 0.0 1.8 9.5 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 KXX75211.1 - 4.5e-07 30.2 0.0 2.2e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_MalT PF17874.1 KXX75211.1 - 1.7e-06 27.7 1.0 3.2e-06 26.8 1.0 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 KXX75211.1 - 5.5e-06 26.9 0.0 2 9.1 0.0 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 KXX75211.1 - 1.1e-05 24.8 0.0 2.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 KXX75211.1 - 1.6e-05 25.3 0.0 5.6 7.6 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX75211.1 - 0.0034 18.1 0.6 89 4.3 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX75211.1 - 0.0036 17.4 2.1 44 4.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KXX75211.1 - 0.064 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold ANAPC3 PF12895.7 KXX75211.1 - 0.067 13.4 0.0 45 4.4 0.0 3.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ARD PF03079.14 KXX75212.1 - 9.5e-45 152.6 0.0 1.1e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KXX75212.1 - 1.2e-08 34.6 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXX75212.1 - 3.7e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain DER1 PF04511.15 KXX75213.1 - 1.3e-51 175.3 6.0 1.5e-51 175.1 6.0 1.0 1 0 0 1 1 1 1 Der1-like family MBOAT PF03062.19 KXX75215.1 - 2.6e-58 198.0 0.8 4.1e-58 197.4 0.8 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.21 KXX75215.1 - 0.0049 16.6 2.3 0.0049 16.6 2.3 2.0 2 0 0 2 2 2 1 PAP2 superfamily MMM1 PF10296.9 KXX75216.1 - 4.2e-139 463.2 0.2 1.3e-137 458.3 0.2 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Sec1 PF00995.23 KXX75217.1 - 5.2e-122 409.0 0.0 1.6e-121 407.4 0.0 1.6 1 1 0 1 1 1 1 Sec1 family adh_short PF00106.25 KXX75219.1 - 7.8e-32 110.3 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX75219.1 - 4.5e-21 75.5 0.0 6.6e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX75219.1 - 8.8e-11 42.0 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX75219.1 - 1.8e-07 30.9 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX75219.1 - 0.00067 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXX75219.1 - 0.0016 17.6 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXX75219.1 - 0.0023 17.1 0.0 0.003 16.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX75219.1 - 0.0036 16.7 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ribosomal_60s PF00428.19 KXX75219.1 - 0.0047 17.5 0.6 0.0096 16.5 0.6 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein NAD_binding_10 PF13460.6 KXX75219.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KXX75219.1 - 0.14 11.7 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family UAA PF08449.11 KXX75220.1 - 1.1e-08 34.7 17.2 1.4e-08 34.3 17.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXX75220.1 - 0.0086 16.2 5.7 0.0086 16.2 5.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.20 KXX75220.1 - 7.6 5.5 17.7 0.15 11.0 8.1 2.3 1 1 1 2 2 2 0 Phosphate transporter family CPBP PF02517.16 KXX75221.1 - 2e-14 53.7 5.9 2e-14 53.7 5.9 3.3 3 1 0 3 3 3 2 CPBP intramembrane metalloprotease GSH_synth_ATP PF03917.17 KXX75222.1 - 9.5e-50 169.4 0.0 1.1e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KXX75222.1 - 0.00031 21.2 0.0 0.00058 20.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SUN PF03856.13 KXX75223.1 - 9e-89 297.1 11.3 1.1e-88 296.8 11.3 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) RHSP PF07999.11 KXX75223.1 - 0.012 14.4 0.1 0.018 13.9 0.1 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein Sortilin-Vps10 PF15902.5 KXX75224.1 - 1.1e-287 953.9 18.3 7.7e-146 486.4 3.3 3.1 2 1 1 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KXX75224.1 - 5.3e-89 297.0 23.0 5.9e-46 156.9 12.6 2.6 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KXX75224.1 - 1.6e-15 54.5 31.0 0.079 13.0 0.2 11.9 11 0 0 11 11 11 6 BNR/Asp-box repeat DUF2561 PF10812.8 KXX75224.1 - 0.004 17.2 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) BNR_6 PF15899.5 KXX75224.1 - 0.011 15.7 16.0 2.4 8.5 0.0 6.8 8 0 0 8 8 8 0 BNR-Asp box repeat Proteasom_Rpn13 PF04683.13 KXX75224.1 - 0.097 13.2 0.0 0.49 11.0 0.0 2.3 2 0 0 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor DAGAT PF03982.13 KXX75225.1 - 7.1e-91 304.2 0.0 1e-90 303.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase LAM_C PF12544.8 KXX75227.1 - 0.00014 22.0 0.1 0.00033 20.8 0.1 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 KXX75227.1 - 0.015 15.7 0.0 0.14 12.5 0.0 2.4 2 1 0 2 2 2 0 Radical SAM superfamily Hydantoinase_B PF02538.14 KXX75227.1 - 0.12 10.8 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase zf-H2C2_2 PF13465.6 KXX75228.1 - 4.9e-12 45.7 20.0 4.5e-07 30.0 1.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXX75228.1 - 1.2e-07 31.8 26.9 0.0045 17.4 7.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX75228.1 - 9.9e-05 22.9 23.5 0.041 14.7 6.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KXX75228.1 - 0.02 14.7 0.9 0.053 13.4 0.9 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 KXX75228.1 - 0.2 11.5 4.2 1.1 9.1 0.2 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) Rpr2 PF04032.16 KXX75228.1 - 0.25 11.6 3.4 5.5 7.3 1.5 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_6 PF13912.6 KXX75228.1 - 0.79 9.8 22.3 1.7 8.7 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.9 KXX75228.1 - 0.9 9.6 5.7 2.7 8.1 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger domain PyrI_C PF02748.15 KXX75228.1 - 2.3 8.2 3.8 0.68 9.9 0.1 2.0 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 KXX75228.1 - 2.7 8.1 9.8 1.2 9.2 5.5 2.4 1 1 1 2 2 2 0 BED zinc finger GAGA PF09237.11 KXX75228.1 - 3 7.7 6.0 14 5.6 1.5 2.5 1 1 1 2 2 2 0 GAGA factor zf-C2H2_jaz PF12171.8 KXX75228.1 - 5.7 7.4 14.4 5.8 7.3 4.3 3.7 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KXX75228.1 - 6.6 6.9 8.1 5.9 7.1 2.0 2.6 1 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KXX75228.1 - 7.7 6.6 9.2 79 3.4 0.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 KXX75228.1 - 9.7 6.6 12.8 2.9 8.3 8.0 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding COesterase PF00135.28 KXX75229.1 - 9.1e-84 282.1 0.0 1.1e-83 281.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX75229.1 - 0.0067 16.3 0.7 0.019 14.9 0.7 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Diphthami_syn_2 PF01902.17 KXX75230.1 - 3.2e-22 79.1 0.0 8.8e-16 58.1 0.0 3.6 3 1 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KXX75230.1 - 4.4e-08 33.2 0.7 2.3e-05 24.4 0.0 3.8 4 0 0 4 4 4 1 Endoribonuclease L-PSP DUF962 PF06127.11 KXX75231.1 - 3.7e-25 87.8 0.9 5.1e-25 87.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF3262 PF11660.8 KXX75231.1 - 0.044 14.2 0.4 12 6.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) SHS2_Rpb7-N PF03876.17 KXX75232.1 - 7.8e-15 55.0 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KXX75232.1 - 8.2e-09 35.7 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain MFS_1 PF07690.16 KXX75233.1 - 1.9e-28 99.4 42.1 1.1e-20 73.9 16.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2427 PF10348.9 KXX75233.1 - 0.007 16.1 0.2 0.007 16.1 0.2 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) Pex24p PF06398.11 KXX75233.1 - 2.5 7.0 4.9 0.31 10.0 0.1 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin OATP PF03137.20 KXX75233.1 - 9 4.5 13.2 0.3 9.3 2.7 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1996 PF09362.10 KXX75234.1 - 1.3e-68 231.5 0.1 1.6e-68 231.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HIPIP PF01355.17 KXX75234.1 - 0.012 15.9 0.5 2.2 8.7 0.1 2.5 2 0 0 2 2 2 0 High potential iron-sulfur protein Na_Ca_ex PF01699.24 KXX75235.1 - 2.6e-24 85.9 27.6 6.4e-16 58.7 11.2 3.7 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KXX75235.1 - 2.9e-17 63.1 10.9 2.9e-17 63.1 10.9 4.3 5 0 0 5 5 5 1 Inner membrane component domain AAA PF00004.29 KXX75236.1 - 7.6e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX75236.1 - 2.2e-14 53.0 0.0 4.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXX75236.1 - 1.1e-07 32.0 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXX75236.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXX75236.1 - 4.3e-06 27.2 0.0 0.00011 22.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 KXX75236.1 - 5.1e-06 26.3 4.5 1.4e-05 25.0 4.5 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KXX75236.1 - 2.4e-05 24.6 0.2 0.006 16.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXX75236.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXX75236.1 - 0.00063 20.3 0.1 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KXX75236.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KXX75236.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXX75236.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KXX75236.1 - 0.0031 17.4 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXX75236.1 - 0.0081 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KXX75236.1 - 0.0088 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 KXX75236.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXX75236.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KXX75236.1 - 0.015 15.0 0.2 0.051 13.2 0.2 2.0 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 KXX75236.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KXX75236.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXX75236.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KXX75236.1 - 0.03 13.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KXX75236.1 - 0.032 14.0 0.0 0.1 12.3 0.0 1.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXX75236.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KXX75236.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXX75236.1 - 0.052 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain HR1 PF02185.16 KXX75236.1 - 0.058 13.5 1.1 0.14 12.3 1.1 1.6 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 KXX75236.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 KXX75236.1 - 0.065 13.5 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Zeta_toxin PF06414.12 KXX75236.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RdRP PF05183.12 KXX75237.1 - 3.7e-176 587.3 0.0 5.5e-176 586.7 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KXX75237.1 - 1.2e-05 25.0 0.0 3.9e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.7 KXX75238.1 - 1.6e-10 41.9 1.3 2e-10 41.7 0.1 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX75238.1 - 1.9e-09 37.6 0.0 6.6e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX75238.1 - 3.5e-05 23.2 0.0 0.00013 21.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 KXX75238.1 - 0.00027 22.0 0.2 0.18 13.0 0.1 2.8 2 0 0 2 2 2 2 EthD domain Ndr PF03096.14 KXX75238.1 - 0.0022 16.8 0.0 0.0051 15.6 0.0 1.5 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 KXX75238.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Histone PF00125.24 KXX75239.1 - 1.9e-18 67.1 0.0 2.4e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KXX75239.1 - 3.3e-12 45.9 0.1 3.3e-12 45.9 0.1 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KXX75239.1 - 2.9e-05 24.2 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M64 PF09471.10 KXX75239.1 - 0.037 13.6 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 zf-C2H2_4 PF13894.6 KXX75240.1 - 0.0055 17.4 0.1 2.5 9.2 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger F-box PF00646.33 KXX75241.1 - 2e-08 33.9 0.3 4.6e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX75241.1 - 3.7e-08 33.1 0.5 8.6e-08 32.0 0.5 1.6 1 0 0 1 1 1 1 F-box-like DUF2688 PF10892.8 KXX75241.1 - 0.066 12.7 0.1 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Meth_synt_2 PF01717.18 KXX75242.1 - 7.9e-06 25.4 0.0 0.00065 19.1 0.0 2.8 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXX75242.1 - 0.0049 16.4 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain Y_phosphatase PF00102.27 KXX75243.1 - 7.6e-55 186.0 0.0 7.2e-31 107.6 0.0 3.8 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 KXX75243.1 - 9.8e-13 48.6 0.0 2.9e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KXX75243.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KXX75243.1 - 0.12 12.1 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Inositol_P PF00459.25 KXX75244.1 - 3.5e-32 112.0 0.0 2.6e-31 109.1 0.0 2.3 1 1 0 1 1 1 1 Inositol monophosphatase family R3H PF01424.22 KXX75245.1 - 2.6e-11 43.3 0.3 5.5e-11 42.3 0.3 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KXX75245.1 - 4.3e-08 32.9 0.0 7.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RCS1 PF07326.11 KXX75245.1 - 0.022 14.7 0.6 0.038 13.9 0.6 1.3 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 RRM_2 PF04059.12 KXX75245.1 - 0.029 14.6 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Strabismus PF06638.11 KXX75246.1 - 0.32 9.6 0.5 0.43 9.2 0.5 1.1 1 0 0 1 1 1 0 Strabismus protein RCC1 PF00415.18 KXX75247.1 - 3.6e-35 120.3 21.2 7.2e-08 32.9 0.5 7.7 7 1 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXX75247.1 - 2.3e-20 71.8 29.1 6.5e-08 32.2 1.8 5.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.17 KXX75248.1 - 3e-16 59.2 0.0 4.4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KXX75248.1 - 2.1e-06 28.0 0.0 6.7e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXX75248.1 - 4.4e-06 27.2 0.1 1.1e-05 25.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXX75248.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXX75248.1 - 0.016 15.5 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KXX75248.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KXX75248.1 - 0.037 13.7 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 KXX75248.1 - 0.062 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain DUF1752 PF08550.10 KXX75248.1 - 0.11 12.3 0.9 0.26 11.2 0.9 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) 3HCDH_N PF02737.18 KXX75248.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HA2 PF04408.23 KXX75249.1 - 1.2e-21 77.1 0.0 3.3e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXX75249.1 - 2.8e-19 69.2 0.0 5.7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXX75249.1 - 2.6e-13 50.3 0.0 7e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KXX75249.1 - 8.8e-09 35.6 0.2 1.8e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KXX75249.1 - 2.7e-06 27.3 0.4 7.3e-06 25.9 0.4 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXX75249.1 - 5e-06 26.8 0.1 1.7e-05 25.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXX75249.1 - 0.00019 20.6 0.0 0.00047 19.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXX75249.1 - 0.0003 20.5 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXX75249.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KXX75249.1 - 0.014 15.4 0.0 5.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KXX75249.1 - 0.022 14.2 0.1 0.085 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KXX75249.1 - 0.022 15.1 0.1 0.054 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXX75249.1 - 0.032 14.3 0.2 0.26 11.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXX75249.1 - 0.044 14.3 0.4 0.36 11.3 0.2 2.5 1 1 1 2 2 2 0 ABC transporter AAA_16 PF13191.6 KXX75249.1 - 0.064 13.6 0.3 0.3 11.5 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain Herpes_ori_bp PF02399.15 KXX75249.1 - 0.17 9.9 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Alk_phosphatase PF00245.20 KXX75250.1 - 4.9e-101 338.7 0.0 6e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KXX75250.1 - 1.8e-05 24.2 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily LRR_9 PF14580.6 KXX75251.1 - 0.0023 17.5 0.4 0.0059 16.1 0.4 1.6 1 0 0 1 1 1 1 Leucine-rich repeat Rad9 PF04139.13 KXX75252.1 - 1.9e-41 142.2 0.1 2.5e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 HEAT_2 PF13646.6 KXX75253.1 - 8.8e-12 45.3 11.4 0.056 13.9 0.0 8.6 6 2 2 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KXX75253.1 - 5.4e-09 36.5 0.1 0.0056 17.3 0.0 5.9 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KXX75253.1 - 6.4e-08 32.2 22.6 0.063 13.6 0.1 10.8 11 0 0 11 11 11 3 HEAT repeat Cnd1 PF12717.7 KXX75253.1 - 9.3e-08 32.3 0.2 0.28 11.2 0.0 5.2 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXX75253.1 - 0.0063 17.0 22.0 0.52 10.9 0.6 8.1 8 0 0 8 8 8 2 HEAT-like repeat CLASP_N PF12348.8 KXX75253.1 - 0.021 14.4 7.5 0.61 9.6 0.0 5.3 6 1 1 7 7 7 0 CLASP N terminal MSA-2c PF12238.8 KXX75253.1 - 0.16 12.0 1.2 0.39 10.7 1.2 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c UNC45-central PF11701.8 KXX75253.1 - 0.42 10.6 5.1 17 5.3 0.0 5.2 3 2 2 5 5 5 0 Myosin-binding striated muscle assembly central DUF1640 PF07798.11 KXX75254.1 - 5.4e-33 114.5 1.7 7.2e-33 114.1 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Abhydrolase_6 PF12697.7 KXX75255.1 - 2.9e-18 67.3 3.9 5.6e-18 66.4 3.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX75255.1 - 4.4e-12 45.8 0.0 2.5e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX75255.1 - 4.8e-12 46.1 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 KXX75255.1 - 2.1e-08 34.0 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KXX75255.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 KXX75255.1 - 0.0033 17.3 0.4 0.012 15.5 0.4 1.8 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KXX75255.1 - 0.011 15.4 0.0 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein PTPlike_phytase PF14566.6 KXX75255.1 - 0.034 14.3 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KXX75255.1 - 0.038 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LIDHydrolase PF10230.9 KXX75255.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 KXX75255.1 - 0.045 13.4 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF900 PF05990.12 KXX75255.1 - 0.11 11.9 0.0 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Y_phosphatase3 PF13350.6 KXX75255.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family LCAT PF02450.15 KXX75255.1 - 0.25 10.5 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Arf PF00025.21 KXX75258.1 - 2.9e-58 196.2 0.0 3.5e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXX75258.1 - 5.6e-10 39.5 0.1 7.3e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXX75258.1 - 3.5e-08 33.0 0.0 6.1e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KXX75258.1 - 2.6e-07 30.2 0.0 3.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KXX75258.1 - 4.9e-07 29.5 0.0 6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KXX75258.1 - 1.8e-05 24.3 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 KXX75258.1 - 0.00055 19.0 0.1 0.00084 18.4 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KXX75258.1 - 0.025 14.1 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain VWA_CoxE PF05762.14 KXX75258.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein tRNA-synt_2d PF01409.20 KXX75259.1 - 5.6e-82 274.9 0.0 1.4e-81 273.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KXX75259.1 - 3.9e-18 65.5 0.6 8.5e-18 64.4 0.6 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KXX75259.1 - 1.1e-08 34.8 0.0 2.2e-06 27.3 0.0 3.0 2 1 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 KXX75259.1 - 7.9e-06 25.8 4.3 2e-05 24.5 4.3 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 KXX75259.1 - 9.2e-05 21.7 2.6 0.0013 17.8 0.1 2.8 3 1 1 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KXX75259.1 - 0.017 15.1 0.0 0.1 12.6 0.0 2.1 1 1 1 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF1938 PF09153.10 KXX75259.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Glyco_transf_22 PF03901.17 KXX75260.1 - 9.9e-61 206.2 17.0 1.2e-60 205.9 17.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KXX75260.1 - 0.67 10.1 14.5 0.81 9.9 11.2 2.3 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Skp1 PF01466.19 KXX75261.1 - 5.8e-29 100.0 0.7 1e-28 99.2 0.7 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXX75261.1 - 1.1e-21 76.8 0.1 2.8e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Trnau1ap PF17654.1 KXX75261.1 - 0.045 14.6 1.7 0.081 13.8 1.7 1.6 1 1 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins Transcrip_reg PF01709.20 KXX75262.1 - 2.9e-73 246.2 0.1 3.3e-73 246.0 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator Pet100 PF09803.9 KXX75263.1 - 5.9e-20 71.6 0.3 7.2e-20 71.3 0.3 1.1 1 0 0 1 1 1 1 Pet100 p450 PF00067.22 KXX75264.1 - 5.6e-64 216.6 0.0 5.2e-63 213.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Asn_synthase PF00733.21 KXX75265.1 - 1.4e-74 251.9 0.2 2.1e-74 251.3 0.2 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KXX75265.1 - 9.4e-36 122.4 0.0 1.6e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXX75265.1 - 3.3e-32 111.5 0.0 1.1e-31 109.7 0.0 2.0 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXX75265.1 - 0.0034 16.9 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein p450 PF00067.22 KXX75266.1 - 5.1e-62 210.1 0.0 6.1e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KXX75269.1 - 4.8e-21 75.0 0.9 8.6e-21 74.1 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX75269.1 - 1.5e-06 28.2 0.1 3.4e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 KXX75270.1 - 4e-35 121.4 53.0 8.1e-35 120.4 53.0 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX75270.1 - 4.1e-08 32.5 14.9 4.1e-08 32.5 14.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3325 PF11804.8 KXX75270.1 - 0.013 15.6 1.7 0.013 15.6 1.7 4.4 5 1 0 5 5 5 0 Protein of unknown function (DUF3325) OATP PF03137.20 KXX75270.1 - 0.038 12.3 25.8 0.012 13.9 19.9 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ketoacyl-synt PF00109.26 KXX75271.1 - 1.4e-74 250.9 0.1 4.7e-74 249.1 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXX75271.1 - 7.4e-52 176.4 0.6 1.2e-51 175.8 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.10 KXX75271.1 - 3.5e-50 170.4 2.1 4e-50 170.2 0.3 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KXX75271.1 - 3e-47 161.7 0.1 7e-47 160.5 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX75271.1 - 2.1e-33 114.8 0.1 6.7e-33 113.2 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXX75271.1 - 1.7e-14 54.2 0.0 4.8e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXX75271.1 - 3.1e-08 33.3 0.1 9.8e-08 31.7 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KXX75271.1 - 1.4e-07 31.5 0.1 3.9e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KXX75271.1 - 3.4e-07 30.5 0.0 1.3e-06 28.6 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KXX75271.1 - 1.4e-06 28.1 0.4 3.8e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXX75271.1 - 6.3e-06 25.7 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.6 KXX75271.1 - 0.0028 18.7 0.0 0.014 16.4 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SAT PF16073.5 KXX75271.1 - 0.0037 17.0 2.4 0.16 11.7 0.8 3.6 3 1 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KXX75271.1 - 0.066 13.1 0.4 0.71 9.8 0.4 2.6 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Filament_head PF04732.14 KXX75272.1 - 0.59 11.0 10.3 2.4 9.1 0.1 2.7 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region ADH_zinc_N_2 PF13602.6 KXX75273.1 - 1.2e-12 49.0 0.0 2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX75273.1 - 7.2e-10 38.9 0.0 2.1e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX75273.1 - 0.00012 21.9 0.0 0.0013 18.6 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXX75273.1 - 0.00097 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KXX75273.1 - 0.0038 17.1 0.1 0.0084 16.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXX75273.1 - 0.0058 16.2 0.2 0.0089 15.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXX75273.1 - 0.0071 15.8 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXX75273.1 - 0.0089 15.2 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain ADH_N_2 PF16884.5 KXX75273.1 - 0.035 14.0 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase GDP_Man_Dehyd PF16363.5 KXX75273.1 - 0.056 12.8 0.3 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 KXX75273.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FSH1 PF03959.13 KXX75274.1 - 1.7e-31 109.6 0.0 4.7e-31 108.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXX75274.1 - 0.00012 22.7 0.1 0.00015 22.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX75274.1 - 0.00088 19.1 0.4 0.093 12.5 0.2 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KXX75274.1 - 0.072 12.7 0.1 3 7.4 0.0 2.5 1 1 0 2 2 2 0 alpha/beta hydrolase fold HET PF06985.11 KXX75276.1 - 4e-37 127.8 0.1 6.9e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.26 KXX75277.1 - 5e-12 45.9 0.0 9.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX75277.1 - 7e-07 29.1 0.1 4.5e-05 23.3 0.1 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXX75277.1 - 0.00093 20.3 0.0 0.0029 18.6 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pet127 PF08634.10 KXX75278.1 - 9.3e-119 395.9 1.1 1.5e-118 395.2 1.1 1.4 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Rhomboid PF01694.22 KXX75279.1 - 1.8e-34 118.9 8.1 6.5e-34 117.1 7.1 2.1 2 0 0 2 2 2 1 Rhomboid family PEPCK_N PF17297.2 KXX75279.1 - 0.03 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain Abhydrolase_1 PF00561.20 KXX75280.1 - 1.4e-14 54.4 0.1 2.7e-14 53.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX75280.1 - 1.7e-08 34.1 0.0 3.3e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 KXX75280.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 Cutinase DUF4746 PF15928.5 KXX75281.1 - 0.31 10.4 6.6 0.35 10.2 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 KXX75281.1 - 3.1 7.5 12.9 4.5 7.0 12.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cohesin_load PF10345.9 KXX75283.1 - 3e-171 570.9 7.1 4e-171 570.5 7.1 1.1 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KXX75283.1 - 3.1 8.2 8.4 2.3 8.6 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CN_hydrolase PF00795.22 KXX75284.1 - 1.9e-16 60.2 0.0 1.5e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KXX75285.1 - 3.8e-12 46.1 0.0 2.8e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DUF4596 PF15363.6 KXX75286.1 - 4.2 7.7 5.4 11 6.3 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) DER1 PF04511.15 KXX75288.1 - 1.9e-26 93.2 3.1 2.2e-26 93.0 3.1 1.0 1 0 0 1 1 1 1 Der1-like family ArgJ PF01960.18 KXX75289.1 - 6.1e-152 505.7 0.2 6.9e-152 505.5 0.2 1.0 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.11 KXX75290.1 - 2.9e-23 82.1 0.0 8.1e-23 80.6 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXX75290.1 - 2.1e-12 47.6 0.0 4.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXX75290.1 - 4.4e-12 46.1 0.0 4.1e-09 36.4 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_14 PF13173.6 KXX75290.1 - 2.8e-07 30.6 0.0 1.2e-06 28.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX75290.1 - 1.7e-06 28.5 0.0 0.00013 22.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXX75290.1 - 3.5e-05 23.6 0.0 8.8e-05 22.3 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KXX75290.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX75290.1 - 8.5e-05 22.9 0.1 0.14 12.4 0.0 2.6 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KXX75290.1 - 9.2e-05 22.3 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.13 KXX75290.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KXX75290.1 - 0.0032 16.9 0.0 0.033 13.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 KXX75290.1 - 0.0049 17.2 0.0 0.017 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain MeaB PF03308.16 KXX75290.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_pol3_gamma3 PF12169.8 KXX75290.1 - 0.01 15.8 0.3 0.39 10.6 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III KTI12 PF08433.10 KXX75290.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.15 KXX75290.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 KXX75290.1 - 0.017 15.0 0.2 0.065 13.1 0.1 2.0 1 1 1 2 2 2 0 NTPase AAA_11 PF13086.6 KXX75290.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX75290.1 - 0.025 14.3 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXX75290.1 - 0.029 14.4 0.1 0.12 12.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KXX75290.1 - 0.03 13.7 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KXX75290.1 - 0.039 14.3 0.1 0.11 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KXX75290.1 - 0.057 13.2 0.1 1.9 8.2 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase DUF5119 PF17145.4 KXX75290.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5119) DUF2075 PF09848.9 KXX75290.1 - 0.17 11.1 0.1 3.3 6.9 0.1 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1232 PF06803.12 KXX75291.1 - 0.29 10.9 0.5 0.46 10.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) IGPD PF00475.18 KXX75292.1 - 2e-60 203.3 0.5 2.7e-60 202.8 0.5 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase BCS1_N PF08740.11 KXX75293.1 - 1.1e-25 90.7 0.0 2.6e-25 89.5 0.0 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KXX75293.1 - 8.3e-17 61.9 0.0 1.5e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX75293.1 - 0.0082 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KXX75293.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXX75293.1 - 0.033 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXX75293.1 - 0.033 14.7 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXX75293.1 - 0.033 13.4 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 KXX75293.1 - 0.038 14.4 0.1 0.14 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 KXX75293.1 - 0.11 11.7 0.0 0.94 8.6 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain ABC_tran PF00005.27 KXX75293.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXX75293.1 - 0.17 12.2 0.0 0.68 10.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 KXX75293.1 - 0.19 11.5 0.0 0.61 9.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain HET PF06985.11 KXX75294.1 - 6.1e-27 94.8 0.0 9.8e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SpoVAD PF07451.11 KXX75294.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Peptidase_S8 PF00082.22 KXX75295.1 - 9e-37 126.9 3.5 2.1e-36 125.7 3.5 1.6 1 1 0 1 1 1 1 Subtilase family FHA PF00498.26 KXX75296.1 - 3.1e-06 27.4 0.0 6.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain RRM_1 PF00076.22 KXX75297.1 - 1.9e-59 197.4 0.1 1.4e-19 69.7 0.0 6.0 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXX75297.1 - 2.5e-07 31.1 0.0 4.2 7.6 0.0 6.3 5 1 1 6 6 6 3 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KXX75297.1 - 3.2e-06 27.1 2.3 0.0096 15.7 0.0 3.1 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KXX75297.1 - 0.005 16.9 0.0 23 5.2 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif Herpes_BLLF1 PF05109.13 KXX75298.1 - 1.9 6.4 10.5 2.7 5.9 10.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TACC_C PF05010.14 KXX75299.1 - 0.16 11.8 27.9 0.073 12.9 6.1 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Ribonuc_red_lgN PF00317.21 KXX75299.1 - 0.22 11.5 1.2 6.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain DUF724 PF05266.14 KXX75299.1 - 0.23 11.3 23.1 0.037 13.9 2.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) p450 PF00067.22 KXX75299.1 - 0.26 10.0 8.6 0.24 10.1 1.2 2.2 1 1 0 2 2 2 0 Cytochrome P450 SlyX PF04102.12 KXX75299.1 - 0.26 11.9 0.3 0.26 11.9 0.3 5.3 2 1 3 6 6 5 0 SlyX TMF_DNA_bd PF12329.8 KXX75299.1 - 0.42 10.6 22.7 0.67 10.0 0.1 4.4 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding VPS38 PF17649.1 KXX75299.1 - 1.5 7.6 12.0 0.036 12.9 3.1 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting 38 Nas2_N PF18265.1 KXX75299.1 - 2.1 8.3 13.3 4 7.4 2.4 3.8 3 0 0 3 3 3 0 Nas2 N_terminal domain Filament PF00038.21 KXX75299.1 - 2.6 7.6 31.1 1.5 8.3 6.4 2.4 1 1 1 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 KXX75299.1 - 2.6 7.3 20.5 0.17 11.2 9.6 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5446 PF17522.2 KXX75299.1 - 5.6 7.2 14.6 8.6 6.6 5.3 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5446) Cas6b_C PF17262.2 KXX75299.1 - 8.6 6.5 6.3 1.3 9.2 0.6 2.3 3 0 0 3 3 3 0 Cas6b C-terminal domain TPR_10 PF13374.6 KXX75301.1 - 1.7e-32 110.4 1.1 8.5e-14 50.9 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXX75301.1 - 4.3e-29 100.6 4.8 2.3e-12 47.0 0.3 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX75301.1 - 2.4e-07 30.3 0.2 0.00032 20.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXX75301.1 - 1.4e-05 25.1 0.0 0.092 13.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX75301.1 - 1.7e-05 25.4 0.0 0.2 12.3 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX75301.1 - 1.9e-05 24.4 0.3 0.054 13.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX75301.1 - 5.1e-05 22.9 0.1 0.063 13.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXX75301.1 - 6.4e-05 23.2 1.7 0.46 11.3 0.1 3.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX75301.1 - 0.0001 22.8 0.0 0.077 13.5 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_5 PF12688.7 KXX75301.1 - 0.0017 18.6 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_MalT PF17874.1 KXX75301.1 - 0.02 14.3 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 MalT-like TPR region TPR_20 PF14561.6 KXX75301.1 - 0.047 14.0 0.1 8.7 6.8 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat PFK PF00365.20 KXX75301.1 - 0.053 12.8 0.1 0.11 11.8 0.0 1.5 1 1 1 2 2 2 0 Phosphofructokinase TPR_8 PF13181.6 KXX75301.1 - 0.086 13.1 0.1 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX75301.1 - 0.27 12.0 1.0 14 6.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 KXX75302.1 - 3e-10 40.1 0.1 0.00069 19.7 0.0 3.9 5 0 0 5 5 5 2 DnaJ domain Pheromone PF08015.11 KXX75302.1 - 2.6 9.2 6.1 2.2 9.4 0.0 3.7 3 1 0 3 3 3 0 Fungal mating-type pheromone FAD_binding_8 PF08022.12 KXX75303.1 - 2.5e-08 34.0 0.0 4.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXX75303.1 - 0.00011 22.4 0.6 0.00011 22.4 0.6 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXX75303.1 - 0.00077 19.6 0.0 0.012 15.8 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 KXX75303.1 - 0.04 14.5 0.1 0.04 14.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF3392 PF11872.8 KXX75303.1 - 0.059 13.6 1.0 7 7.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Ank_2 PF12796.7 KXX75304.1 - 2.8e-50 168.8 4.5 3.6e-16 59.5 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX75304.1 - 5e-47 157.7 8.5 4e-09 36.8 0.0 6.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX75304.1 - 8.7e-39 131.1 7.0 3.4e-09 36.8 0.3 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75304.1 - 5.9e-34 112.3 1.8 0.00052 20.2 0.0 7.5 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KXX75304.1 - 2.1e-32 110.1 4.8 1.5e-05 25.2 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat SPT_ssu-like PF11779.8 KXX75306.1 - 0.08 12.6 0.5 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like HET PF06985.11 KXX75307.1 - 3.6e-25 89.0 0.0 5.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAPS_reduct PF01507.19 KXX75309.1 - 4.2e-20 72.5 0.0 2.1e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family IU_nuc_hydro PF01156.19 KXX75310.1 - 8.8e-13 48.5 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SH3_1 PF00018.28 KXX75312.1 - 8.2e-12 44.5 0.3 3e-11 42.7 0.3 2.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX75312.1 - 5.5e-10 38.9 0.3 4.3e-09 36.1 0.3 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXX75312.1 - 2.5e-08 33.5 0.0 8e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain BUD22 PF09073.10 KXX75312.1 - 0.014 14.8 27.1 1.1 8.5 0.0 2.8 1 1 0 2 2 2 0 BUD22 Aldedh PF00171.22 KXX75313.1 - 2.5e-132 441.7 0.0 2.8e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_PK PF05891.12 KXX75314.1 - 2.2e-29 102.5 0.0 2.7e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Carb_bind PF10645.9 KXX75315.1 - 3.3e-22 78.4 5.8 8e-22 77.2 5.8 1.7 1 0 0 1 1 1 1 Carbohydrate binding CorA PF01544.18 KXX75317.1 - 6e-26 91.4 4.3 2.6e-22 79.5 1.8 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein WD40 PF00400.32 KXX75318.1 - 2.6e-106 344.5 74.1 2.3e-08 34.5 0.2 14.4 15 0 0 15 15 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX75318.1 - 1.8e-32 111.5 17.6 0.0083 16.4 0.0 13.4 3 1 12 15 15 14 10 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXX75318.1 - 1.2e-18 67.6 0.0 2.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KXX75318.1 - 4.1e-17 62.0 28.7 0.34 9.5 0.1 12.1 4 3 7 12 12 12 8 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXX75318.1 - 3.8e-09 36.0 23.1 1.5 7.7 1.0 9.7 2 2 6 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_2 PF12796.7 KXX75318.1 - 7.2e-06 26.5 0.0 0.00097 19.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) WD40_like PF17005.5 KXX75318.1 - 7.5e-06 25.5 0.0 0.11 11.7 0.0 4.1 4 0 0 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KXX75318.1 - 3.8e-05 22.6 14.6 0.092 11.5 0.2 6.0 1 1 2 6 6 6 2 Nup133 N terminal like PD40 PF07676.12 KXX75318.1 - 0.00057 19.8 0.4 21 5.2 0.0 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ank PF00023.30 KXX75318.1 - 0.00061 20.1 0.0 0.0041 17.5 0.0 2.5 2 0 0 2 2 1 1 Ankyrin repeat AAA_16 PF13191.6 KXX75318.1 - 0.0024 18.3 0.6 0.025 15.0 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Ank_5 PF13857.6 KXX75318.1 - 0.011 16.0 0.0 0.042 14.2 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AAA_19 PF13245.6 KXX75318.1 - 0.035 14.4 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_3 PF13606.6 KXX75318.1 - 0.059 14.0 0.0 1.1 10.1 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 KXX75318.1 - 0.084 13.5 0.0 0.49 11.0 0.0 2.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) GlnD_UR_UTase PF08335.11 KXX75319.1 - 0.23 11.5 0.9 12 5.9 0.2 2.3 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase MOZ_SAS PF01853.18 KXX75320.1 - 9.3e-77 256.7 0.0 1.4e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXX75320.1 - 1e-20 73.1 3.3 2.1e-20 72.1 3.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KXX75320.1 - 1.1e-11 44.7 8.0 4e-11 42.8 8.0 2.1 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KXX75320.1 - 0.0001 22.1 8.4 0.0001 22.1 8.4 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KXX75320.1 - 0.06 12.9 2.0 0.061 12.9 0.4 1.9 2 0 0 2 2 2 0 PHD-finger DivIVA PF05103.13 KXX75320.1 - 0.075 13.1 1.5 0.23 11.6 1.5 1.9 1 0 0 1 1 1 0 DivIVA protein C1_1 PF00130.22 KXX75320.1 - 0.11 12.4 1.6 0.26 11.2 1.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_7 PF13508.7 KXX75320.1 - 0.15 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_9 PF13901.6 KXX75320.1 - 0.25 11.3 4.2 0.51 10.3 4.2 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Serglycin PF04360.12 KXX75320.1 - 0.28 11.1 6.9 0.61 10.0 6.9 1.6 1 0 0 1 1 1 0 Serglycin F-box-like PF12937.7 KXX75321.1 - 4.6e-07 29.6 2.6 5.7e-07 29.3 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXX75321.1 - 0.00012 21.9 0.3 0.00036 20.3 0.3 1.8 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.24 KXX75323.1 - 3.2e-16 59.2 21.5 5.8e-15 55.1 4.8 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXX75323.1 - 2.4e-08 33.3 29.4 2.4e-08 33.3 29.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 KXX75324.1 - 7.2e-40 137.1 0.0 9.1e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PEX11 PF05648.14 KXX75325.1 - 4.5e-74 248.7 1.1 5e-74 248.5 1.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Chal_sti_synt_N PF00195.19 KXX75326.1 - 2.2e-21 76.3 0.0 3.2e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 KXX75326.1 - 3.3e-10 40.2 0.0 2.7e-08 33.9 0.0 2.5 1 1 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 KXX75326.1 - 2.2e-06 27.2 0.0 3.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 KXX75326.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NMO PF03060.15 KXX75327.1 - 3.3e-57 194.3 0.1 2.1e-56 191.7 0.1 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXX75327.1 - 8.5e-14 51.3 0.0 1.8e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXX75327.1 - 0.0056 15.8 0.1 0.0095 15.0 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 KXX75327.1 - 0.066 12.4 1.2 0.074 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Thiolase_N PF00108.23 KXX75328.1 - 1.7e-73 247.2 4.5 2.4e-73 246.7 4.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX75328.1 - 6e-44 148.6 0.0 1.2e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXX75328.1 - 0.019 14.5 0.4 0.019 14.5 0.4 2.0 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain FBPase PF00316.20 KXX75329.1 - 4.1e-72 241.6 0.2 5.4e-72 241.2 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 KXX75329.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Hemerythrin PF01814.23 KXX75330.1 - 3.4e-12 47.1 6.7 5e-12 46.6 6.7 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HD_3 PF13023.6 KXX75330.1 - 0.02 14.8 1.3 0.041 13.8 1.3 1.5 1 0 0 1 1 1 0 HD domain Importin_rep_6 PF18829.1 KXX75330.1 - 0.045 13.9 0.1 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Importin repeat 6 FAM195 PF14799.6 KXX75330.1 - 0.051 13.9 1.6 0.098 13.0 0.2 2.0 2 0 0 2 2 2 0 FAM195 family zf-C2H2_2 PF12756.7 KXX75330.1 - 2.7 8.4 5.5 2.8 8.3 2.4 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zn-ribbon_14 PF16503.5 KXX75331.1 - 1e-18 66.5 5.0 1e-18 66.5 5.0 3.9 4 0 0 4 4 4 2 Zinc-ribbon ATP_bind_3 PF01171.20 KXX75331.1 - 7e-17 61.8 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 KXX75331.1 - 0.0028 17.2 0.8 0.0028 17.2 0.8 3.2 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 KXX75331.1 - 0.0093 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase zf-UBR PF02207.20 KXX75331.1 - 0.11 12.7 5.5 3 8.1 0.2 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ThiI PF02568.14 KXX75331.1 - 0.13 11.9 0.0 0.39 10.3 0.0 1.7 1 1 1 2 2 2 0 Thiamine biosynthesis protein (ThiI) DUF2688 PF10892.8 KXX75331.1 - 6 6.4 6.8 34 4.0 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2688) GATA PF00320.27 KXX75331.1 - 8.3 6.1 13.1 0.19 11.3 0.8 3.4 3 1 0 3 3 3 0 GATA zinc finger MWFE PF15879.5 KXX75332.1 - 5.3e-24 84.2 0.1 5.9e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit OCD_Mu_crystall PF02423.15 KXX75333.1 - 7.9e-08 31.6 4.8 4.3e-06 25.9 4.8 2.4 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DUF3530 PF12048.8 KXX75333.1 - 0.037 13.4 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) NAD_binding_7 PF13241.6 KXX75333.1 - 0.12 12.8 0.4 0.25 11.8 0.4 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding MEDS PF14417.6 KXX75333.1 - 0.16 11.8 0.2 3 7.6 0.0 2.3 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain TRAUB PF08164.12 KXX75334.1 - 3.9e-30 104.2 2.6 5.9e-30 103.6 0.1 2.7 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KXX75334.1 - 1.5e-26 93.8 0.5 1.5e-26 93.8 0.5 3.8 4 1 0 4 4 4 1 Apoptosis antagonizing transcription factor Ribosomal_L7Ae PF01248.26 KXX75335.1 - 3.3e-21 74.8 0.9 6.3e-21 73.9 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 KXX75335.1 - 0.031 13.3 0.3 0.037 13.0 0.3 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Pro_CA PF00484.19 KXX75336.1 - 3.9e-46 157.2 0.1 4.8e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ParA PF10609.9 KXX75337.1 - 6.4e-90 300.9 0.0 7.4e-90 300.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXX75337.1 - 3.1e-10 40.2 0.0 2.5e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXX75337.1 - 2.2e-06 27.7 0.2 4.5e-06 26.7 0.1 1.5 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KXX75337.1 - 0.0003 20.2 0.0 0.00054 19.3 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KXX75337.1 - 0.0014 18.2 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KXX75337.1 - 0.0024 17.1 0.0 0.0085 15.3 0.1 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 KXX75337.1 - 0.02 14.7 0.5 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXX75337.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain CBP_BcsQ PF06564.12 KXX75337.1 - 0.069 12.6 0.1 0.24 10.9 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 KXX75337.1 - 0.12 11.4 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Tudor_3 PF18115.1 KXX75338.1 - 3e-07 30.2 0.1 5e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KXX75338.1 - 0.0036 17.3 0.1 0.0064 16.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 KXX75338.1 - 0.017 14.9 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain PKcGMP_CC PF16808.5 KXX75338.1 - 0.094 12.6 0.7 0.31 10.9 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UQ_con PF00179.26 KXX75339.1 - 1.6e-35 121.8 0.1 2e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.13 KXX75340.1 - 2.4e-66 224.7 0.0 2.7e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1778 PF08681.11 KXX75340.1 - 0.013 15.4 0.3 0.032 14.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) DUF2526 PF10735.9 KXX75340.1 - 0.28 11.4 2.5 0.53 10.5 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Annexin PF00191.20 KXX75341.1 - 1e-21 76.7 0.6 9e-06 25.7 0.0 4.5 4 1 0 4 4 4 4 Annexin Zn_clus PF00172.18 KXX75342.1 - 3.3e-08 33.5 11.8 6e-08 32.7 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSP160 PF06933.11 KXX75342.1 - 1.2 7.3 8.3 1.6 6.8 8.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Use1 PF09753.9 KXX75342.1 - 6.9 6.3 6.8 0.78 9.4 2.6 1.5 2 0 0 2 2 2 0 Membrane fusion protein Use1 Corona_nucleoca PF00937.18 KXX75342.1 - 8.8 5.2 9.5 14 4.6 9.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein APG12 PF04110.13 KXX75343.1 - 1.2e-25 89.7 0.0 1.6e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KXX75343.1 - 9.5e-05 22.5 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 KXX75344.1 - 4.1e-108 360.7 0.3 4.7e-108 360.5 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KXX75344.1 - 3e-10 40.0 0.7 3.9e-10 39.6 0.1 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PA PF02225.22 KXX75344.1 - 0.13 12.3 0.8 0.56 10.3 0.3 2.1 2 0 0 2 2 2 0 PA domain GPI2 PF06432.11 KXX75345.1 - 9.9e-105 350.0 0.0 2.6e-54 184.6 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase CNH PF00780.22 KXX75346.1 - 1.4e-66 225.0 0.0 2.4e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KXX75346.1 - 6.5e-33 114.5 0.0 9.9e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KXX75346.1 - 3.6e-10 40.1 0.0 3.6e-09 36.8 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXX75346.1 - 3.5e-05 24.2 0.0 0.0039 17.7 0.0 2.9 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 KXX75346.1 - 0.00062 19.6 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 PH domain Pet191_N PF10203.9 KXX75347.1 - 2.5e-28 98.2 4.8 3.3e-28 97.8 4.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 KXX75347.1 - 0.029 14.3 0.8 0.036 14.0 0.8 1.4 1 1 0 1 1 1 0 COBRA-like protein Abhydrolase_1 PF00561.20 KXX75348.1 - 5.1e-26 91.9 0.3 1.7e-25 90.2 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KXX75348.1 - 4.1e-22 77.5 0.1 8.3e-22 76.5 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KXX75348.1 - 0.0001 21.6 0.0 0.012 14.9 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KXX75348.1 - 0.00099 18.8 0.0 0.96 9.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) TAL_FSA PF00923.19 KXX75349.1 - 2.3e-91 306.1 0.8 2.6e-91 306.0 0.8 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Metallophos PF00149.28 KXX75350.1 - 4.4e-10 40.4 0.0 9.3e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX75350.1 - 1.2e-05 25.5 0.0 2.7e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_36N PF16875.5 KXX75350.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain PBP1_TM PF14812.6 KXX75350.1 - 0.37 11.2 20.5 0.4 11.1 0.2 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CCDC106 PF15794.5 KXX75350.1 - 2.7 7.6 8.4 7.7 6.1 2.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 HNH_2 PF13391.6 KXX75351.1 - 0.0006 19.9 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Sec20 PF03908.13 KXX75352.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Sec20 Sod_Cu PF00080.20 KXX75353.1 - 1.1e-45 155.3 4.9 1.3e-45 155.1 4.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.17 KXX75354.1 - 2e-71 237.4 1.8 2.9e-22 79.2 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KXX75354.1 - 5.7e-25 87.7 0.0 1.3e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KXX75354.1 - 3.1e-07 29.9 0.0 6.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) AFG1_ATPase PF03969.16 KXX75355.1 - 1.1e-53 182.4 0.0 5.9e-24 84.6 0.0 5.0 3 2 2 5 5 5 5 AFG1-like ATPase AAA_16 PF13191.6 KXX75355.1 - 0.001 19.5 0.2 0.014 15.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 KXX75355.1 - 0.0012 18.7 0.0 5.8 6.7 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_5 PF07728.14 KXX75355.1 - 0.0019 18.2 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX75355.1 - 0.0095 16.2 0.0 0.03 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KXX75355.1 - 0.023 13.9 0.1 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.6 KXX75355.1 - 0.037 13.8 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXX75355.1 - 0.075 13.6 0.2 1.3 9.5 0.0 2.7 2 1 1 3 3 3 0 ABC transporter NACHT PF05729.12 KXX75355.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KXX75355.1 - 0.19 12.1 0.0 0.56 10.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXX75355.1 - 0.2 11.1 0.0 0.73 9.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PIF1 PF05970.14 KXX75355.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Glyco_transf_90 PF05686.12 KXX75356.1 - 2.1e-19 69.7 0.0 1.2e-17 63.9 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 Aldedh PF00171.22 KXX75357.1 - 1.8e-83 280.6 0.0 2.2e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MRP-S28 PF10213.9 KXX75358.1 - 6.5e-50 168.8 0.4 1.8e-49 167.4 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein ECR1_N PF14382.6 KXX75360.1 - 8.1e-16 57.5 0.2 1.8e-15 56.4 0.2 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KXX75360.1 - 5e-06 26.8 0.7 9.6e-06 25.9 0.7 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KXX75360.1 - 0.14 12.8 0.5 1.3 9.7 0.1 2.6 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 EGF_CA PF07645.15 KXX75361.1 - 0.025 14.8 3.4 0.061 13.5 3.4 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain HET PF06985.11 KXX75362.1 - 7.9e-22 78.2 0.0 1.2e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acyl_transf_1 PF00698.21 KXX75363.1 - 6.6e-19 68.5 0.1 7.8e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain DUF2458 PF10454.9 KXX75363.1 - 0.00099 18.8 0.1 0.0016 18.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Nucleoporin_C PF03177.14 KXX75364.1 - 5e-174 580.4 14.8 6.4e-174 580.0 14.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KXX75364.1 - 2.6e-94 316.4 0.0 3.4e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.32 KXX75365.1 - 1.8e-28 98.2 31.2 0.00031 21.5 0.6 11.3 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX75365.1 - 2.9e-14 53.1 5.3 0.014 15.6 0.0 7.6 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXX75365.1 - 0.0012 18.7 0.5 0.98 9.4 0.0 4.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXX75365.1 - 0.0031 16.5 5.4 1.1 8.2 0.2 4.8 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_tran_28_C PF04101.16 KXX75366.1 - 1.8e-18 67.1 1.5 2.6e-17 63.3 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain PKI PF02827.16 KXX75366.1 - 0.12 12.5 2.0 0.24 11.6 2.0 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF4834 PF16118.5 KXX75366.1 - 1.4 9.9 4.4 2.7 9.0 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 KXX75366.1 - 2.4 8.1 13.5 3.6 7.5 13.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXX75366.1 - 5.2 6.6 18.6 8.4 5.9 18.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 KXX75366.1 - 5.7 5.8 16.2 8.8 5.1 16.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) HECT PF00632.25 KXX75367.1 - 7.5e-95 317.9 0.0 1.1e-94 317.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KXX75367.1 - 3.7e-34 116.5 23.5 2e-12 47.0 5.3 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KXX75367.1 - 6.5e-20 71.4 0.0 2.2e-19 69.6 0.0 2.0 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.22 KXX75368.1 - 1.7e-16 59.7 0.0 2.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4472 PF14739.6 KXX75368.1 - 0.047 14.4 3.6 0.065 14.0 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Nup35_RRM_2 PF14605.6 KXX75368.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ADIP PF11559.8 KXX75368.1 - 0.064 13.3 3.2 0.087 12.9 3.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 KXX75368.1 - 0.15 9.9 2.0 0.19 9.6 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 KXX75368.1 - 0.16 11.8 6.2 0.23 11.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 KXX75368.1 - 0.42 9.9 5.6 0.58 9.4 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.15 KXX75368.1 - 0.53 10.1 4.5 0.83 9.5 4.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.11 KXX75368.1 - 0.62 8.9 6.7 0.85 8.4 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GRP PF07172.11 KXX75368.1 - 8.4 7.2 18.7 0.2 12.4 11.8 1.8 2 1 0 2 2 2 0 Glycine rich protein family Sedlin_N PF04628.13 KXX75369.1 - 4.7e-13 49.4 0.0 6.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region BA14K PF07886.11 KXX75369.1 - 0.065 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 BA14K-like protein Ribul_P_3_epim PF00834.19 KXX75370.1 - 2.8e-62 209.6 0.0 2.9e-30 105.2 0.0 2.1 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KXX75370.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Aminotran_5 PF00266.19 KXX75371.1 - 5.2e-49 167.2 0.0 6.6e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXX75371.1 - 1.7e-05 23.5 0.0 2.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Rad17 PF03215.15 KXX75372.1 - 1.7e-24 86.7 0.0 1.6e-23 83.6 0.0 2.2 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXX75372.1 - 0.00073 20.0 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXX75372.1 - 0.001 19.5 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXX75372.1 - 0.0023 17.7 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX75372.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXX75372.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KXX75372.1 - 0.021 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 KXX75372.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_19 PF13245.6 KXX75372.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXX75372.1 - 0.085 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KXX75372.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KXX75372.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Questin_oxidase PF14027.6 KXX75373.1 - 2.5e-101 339.6 1.2 3e-101 339.4 1.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like APH PF01636.23 KXX75374.1 - 4.9e-47 160.9 0.6 9.5e-47 159.9 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXX75374.1 - 7.7e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KXX75374.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KXX75374.1 - 0.0017 17.6 0.0 0.007 15.6 0.0 1.9 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.22 KXX75374.1 - 0.019 14.5 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Ank_4 PF13637.6 KXX75375.1 - 5.4e-11 42.8 0.1 4.4e-10 39.9 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX75375.1 - 1.8e-10 40.9 0.2 7.5e-06 26.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75375.1 - 8.7e-10 38.0 0.2 8.2e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXX75375.1 - 1.9e-09 37.9 0.0 2.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXX75375.1 - 1.9e-07 31.2 0.7 0.00072 19.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Metallophos PF00149.28 KXX75376.1 - 1.9e-11 44.8 0.5 3.9e-11 43.9 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PBP1_TM PF14812.6 KXX75376.1 - 0.00039 20.7 5.5 0.00039 20.7 5.5 2.9 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 KXX75376.1 - 0.0022 18.1 3.8 0.23 11.6 2.6 2.2 2 0 0 2 2 2 2 YL1 nuclear protein SART-1 PF03343.13 KXX75376.1 - 0.0072 14.9 4.4 0.12 10.9 0.2 2.1 2 0 0 2 2 2 2 SART-1 family LZ_Tnp_IS66 PF13007.7 KXX75376.1 - 0.24 12.2 7.1 4.5 8.1 0.3 3.4 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain TFIIF_alpha PF05793.12 KXX75376.1 - 0.54 8.8 19.6 0.53 8.8 10.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GEN1_C PF18380.1 KXX75376.1 - 3.8 8.5 8.5 19 6.2 1.6 2.8 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain SR-25 PF10500.9 KXX75376.1 - 5.6 6.5 12.2 3.4 7.2 1.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nop53 PF07767.11 KXX75376.1 - 9.7 5.5 18.4 1.2 8.5 5.0 2.3 2 1 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Ofd1_CTDD PF10637.9 KXX75377.1 - 6.9e-99 330.3 0.0 2.1e-93 312.4 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KXX75377.1 - 1.6e-25 89.6 0.0 1.4e-24 86.6 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXX75377.1 - 7.7e-12 45.9 0.0 1.8e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cys_Met_Meta_PP PF01053.20 KXX75379.1 - 2.2e-53 181.2 0.0 4.1e-53 180.3 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Sybindin PF04099.12 KXX75380.1 - 1.1e-53 181.0 0.0 1.3e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXX75380.1 - 9.6e-09 35.4 0.1 1.5e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 KXX75381.1 - 2.2e-26 92.6 0.2 8e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KXX75381.1 - 6.8e-10 39.5 0.2 9.4e-10 39.0 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KXX75381.1 - 2.7e-06 27.3 0.0 4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KXX75381.1 - 0.0076 16.1 1.1 0.022 14.7 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 KXX75382.1 - 7.2e-20 70.4 2.8 1.1e-19 69.8 2.8 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SUI1 PF01253.22 KXX75383.1 - 3.1e-26 91.7 0.9 5.4e-26 90.9 0.2 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 TnpV PF14198.6 KXX75383.1 - 0.012 15.6 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Img2 PF05046.14 KXX75383.1 - 0.088 13.1 0.2 0.22 11.8 0.1 1.8 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) FYRC PF05965.14 KXX75383.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 F/Y rich C-terminus Methyltransf_11 PF08241.12 KXX75384.1 - 4.1e-13 49.8 0.0 8.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX75384.1 - 1.1e-05 26.0 0.0 2.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX75384.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX75384.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXX75384.1 - 0.011 16.5 0.0 0.039 14.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Zn_clus PF00172.18 KXX75385.1 - 0.16 12.1 4.1 0.59 10.3 4.1 2.0 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-TAZ PF02135.16 KXX75385.1 - 0.32 11.5 2.0 1.1 9.8 0.4 2.6 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2_4 PF13894.6 KXX75385.1 - 2.7 9.1 23.8 1.3 10.1 0.2 6.6 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX75385.1 - 3 8.5 24.9 5.1 7.7 0.5 6.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type HET PF06985.11 KXX75387.1 - 1.4e-22 80.6 0.0 2.3e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PgaD PF13994.6 KXX75387.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein MARVEL PF01284.23 KXX75393.1 - 1.2 9.2 11.3 1.4 9.0 1.4 3.0 2 1 0 3 3 3 0 Membrane-associating domain GWT1 PF06423.12 KXX75393.1 - 5.9 7.0 6.3 3.1 7.9 1.6 2.5 2 1 0 2 2 2 0 GWT1 DAO PF01266.24 KXX75395.1 - 3.8e-40 138.5 4.8 4.8e-40 138.2 4.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX75395.1 - 0.0033 17.6 0.0 0.0094 16.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXX75395.1 - 0.0066 16.5 0.2 0.016 15.2 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding GARS_N PF02844.15 KXX75395.1 - 0.009 16.8 0.0 0.48 11.2 0.0 2.9 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain Peptidase_S15 PF02129.18 KXX75396.1 - 1.6e-41 142.7 0.4 2.3e-41 142.2 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXX75396.1 - 1.9e-39 135.9 0.0 2.9e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KXX75396.1 - 0.029 13.6 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GMC_oxred_N PF00732.19 KXX75397.1 - 2.9e-53 181.2 0.0 5.8e-53 180.2 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX75397.1 - 1.7e-29 103.2 0.1 8.9e-29 100.9 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX75397.1 - 6.2e-09 35.4 0.1 6.7e-05 22.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXX75397.1 - 1.4e-06 28.1 1.7 0.00014 21.6 0.1 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXX75397.1 - 2.6e-06 26.8 0.3 3.9e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXX75397.1 - 3.9e-06 27.0 0.6 2.3e-05 24.5 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX75397.1 - 1.4e-05 24.5 0.1 0.0001 21.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX75397.1 - 0.00025 20.4 0.1 0.00071 18.9 0.2 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KXX75397.1 - 0.0011 18.3 0.1 0.054 12.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXX75397.1 - 0.0036 17.6 0.3 0.039 14.2 0.1 2.3 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.27 KXX75397.1 - 0.0072 16.9 0.4 0.22 12.1 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX75397.1 - 0.0093 15.2 0.4 0.018 14.3 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXX75397.1 - 0.0097 14.6 0.5 0.031 13.0 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KXX75397.1 - 0.015 14.1 0.2 0.022 13.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KXX75397.1 - 0.023 14.7 0.1 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 KXX75397.1 - 0.11 12.2 0.2 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.6 KXX75397.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) SAM_4 PF18017.1 KXX75399.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Methyltransf_23 PF13489.6 KXX75400.1 - 7.5e-26 90.9 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX75400.1 - 1.7e-14 54.3 0.0 4.4e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX75400.1 - 3.2e-12 46.9 0.0 6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX75400.1 - 5.1e-12 46.4 0.0 1.4e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX75400.1 - 3.9e-11 43.0 0.0 3.1e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX75400.1 - 1.1e-05 24.9 0.0 7.2e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXX75400.1 - 6.5e-05 22.3 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KXX75400.1 - 0.0031 17.6 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXX75400.1 - 0.0051 16.3 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.12 KXX75400.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KXX75400.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 KXX75400.1 - 0.039 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 KXX75400.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXX75400.1 - 0.21 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glyco_hydro_18 PF00704.28 KXX75401.1 - 2.3e-45 155.7 0.0 4.3e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KXX75401.1 - 3.2e-14 52.7 0.0 1.4e-05 25.0 0.3 2.7 2 0 0 2 2 2 2 LysM domain Aspzincin_M35 PF14521.6 KXX75401.1 - 2e-08 34.9 0.2 5.6e-08 33.5 0.2 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Chitin_bind_1 PF00187.19 KXX75401.1 - 2.2e-06 28.0 9.3 2.2e-06 28.0 9.3 5.2 2 1 2 4 4 4 1 Chitin recognition protein IPU_b_solenoid PF18783.1 KXX75402.1 - 0.09 12.8 0.4 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat HgmA PF04209.13 KXX75403.1 - 4.8e-189 628.5 0.0 5.7e-189 628.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase NAD_binding_10 PF13460.6 KXX75408.1 - 1.1e-09 38.4 0.0 1.7e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX75408.1 - 3.2e-09 36.7 0.0 4.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family TIP120 PF08623.10 KXX75408.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) TPR_12 PF13424.6 KXX75409.1 - 1.7e-36 124.4 30.5 8.2e-11 42.0 0.5 7.0 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 KXX75409.1 - 6.9e-24 83.0 28.0 0.00033 20.4 0.6 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXX75409.1 - 2.8e-13 48.9 16.7 0.025 14.7 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXX75409.1 - 6.3e-11 41.6 6.6 0.017 14.9 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX75409.1 - 3.8e-10 39.1 13.0 0.013 15.5 0.1 7.1 7 0 0 7 7 6 3 Tetratricopeptide repeat NB-ARC PF00931.22 KXX75409.1 - 1.3e-07 31.1 0.0 2.6e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXX75409.1 - 2.5e-07 31.3 2.8 9.5e-07 29.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TPR_14 PF13428.6 KXX75409.1 - 5e-06 26.9 30.3 0.052 14.4 0.2 8.8 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX75409.1 - 9.4e-06 26.2 29.8 0.072 13.8 0.3 7.7 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX75409.1 - 1.2e-05 25.2 7.5 3 8.3 0.0 6.9 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXX75409.1 - 2.9e-05 24.4 18.5 0.14 12.9 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX75409.1 - 0.0023 18.4 16.3 2.6 8.6 2.4 6.2 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXX75409.1 - 0.0088 16.6 35.1 0.15 12.7 1.7 7.1 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_22 PF13401.6 KXX75409.1 - 0.01 16.1 0.0 0.04 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KXX75409.1 - 0.018 15.1 0.0 0.049 13.7 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 KXX75409.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_20 PF14561.6 KXX75409.1 - 0.038 14.3 4.1 8.6 6.8 0.4 4.5 4 2 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX75409.1 - 0.1 12.9 0.5 8.2 6.7 0.0 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXX75409.1 - 2.7 8.6 4.4 1.5e+02 3.1 0.3 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXX75409.1 - 2.8 8.1 19.5 0.69 10.1 0.1 5.4 2 2 3 6 6 6 0 Tetratricopeptide repeat Defb50 PF17546.2 KXX75411.1 - 0.1 12.5 1.0 14 5.7 0.1 2.8 3 0 0 3 3 3 0 Beta defensin 50 HET PF06985.11 KXX75413.1 - 1.1e-36 126.4 0.8 1.8e-36 125.6 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CDH-cyt PF16010.5 KXX75414.1 - 2.2e-49 167.6 0.5 3.8e-49 166.8 0.5 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase ORC6 PF05460.13 KXX75414.1 - 5 6.3 6.3 7.8 5.7 6.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Phage_NinH PF06322.11 KXX75415.1 - 0.0086 16.0 0.1 25 4.8 0.0 3.2 3 0 0 3 3 3 0 Phage NinH protein Organ_specific PF10950.8 KXX75415.1 - 0.011 16.4 2.6 0.042 14.6 2.7 1.8 1 1 0 1 1 1 0 Organ specific protein Calici_PP_N PF08405.11 KXX75415.1 - 0.1 11.4 0.8 29 3.3 0.0 3.0 1 1 2 3 3 3 0 Viral polyprotein N-terminal Nuc_N PF14448.6 KXX75415.1 - 1.1 9.1 3.0 54 3.8 0.2 3.0 3 0 0 3 3 3 0 Nuclease N terminal DUF1972 PF09314.11 KXX75415.1 - 1.4 8.5 6.5 6.8 6.2 0.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1972) HTH_Tnp_Mu_2 PF09039.11 KXX75415.1 - 2.5 8.2 10.3 16 5.6 0.4 3.8 1 1 3 4 4 4 0 Mu DNA binding, I gamma subdomain DUF3889 PF13028.6 KXX75415.1 - 3 7.8 15.7 7.9 6.5 0.7 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3889) SnoaL PF07366.12 KXX75415.1 - 4.8 7.0 7.7 2.5 7.9 0.9 2.4 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase MFS_1 PF07690.16 KXX75416.1 - 6.2e-34 117.5 36.3 6.2e-34 117.5 36.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX75416.1 - 2.8e-05 22.7 6.5 4.6e-05 22.0 6.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 KXX75417.1 - 1.6e-82 277.4 0.0 2.3e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXX75417.1 - 5.3e-47 160.5 0.0 1.1e-23 83.7 0.0 4.2 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KXX75417.1 - 1.3e-09 38.2 0.0 3.9e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3328 PF11807.8 KXX75418.1 - 3.7e-50 170.7 0.0 6.1e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_3 PF01494.19 KXX75419.1 - 2.3e-15 56.7 1.4 1.4e-13 50.8 0.5 2.9 2 1 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KXX75419.1 - 0.00016 20.9 0.2 0.00063 18.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX75419.1 - 0.00026 20.3 0.0 0.00059 19.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX75419.1 - 0.0016 18.1 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX75419.1 - 0.017 15.6 0.0 0.046 14.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX75419.1 - 0.052 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXX75419.1 - 0.068 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXX75419.1 - 0.15 11.3 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trypan_PARP PF05887.11 KXX75421.1 - 0.00033 20.6 10.2 0.00064 19.7 10.2 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) zf-GRF PF06839.12 KXX75421.1 - 0.17 12.0 11.4 2.7 8.2 0.3 2.4 2 0 0 2 2 2 0 GRF zinc finger MFS_1 PF07690.16 KXX75422.1 - 1.1e-25 90.4 40.3 1.4e-16 60.3 5.8 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX75422.1 - 2.7e-07 29.8 6.1 2.7e-07 29.8 6.1 3.0 3 1 1 4 4 4 1 Sugar (and other) transporter DUF2583 PF10762.9 KXX75422.1 - 0.63 10.5 3.4 16 6.0 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2583) Glyoxalase PF00903.25 KXX75423.1 - 7.6e-08 32.6 9.4 3.5e-06 27.2 3.9 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ketoacyl-synt PF00109.26 KXX75424.1 - 5.6e-70 235.8 0.0 1e-69 234.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX75424.1 - 3.6e-61 206.2 0.0 7.9e-61 205.1 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXX75424.1 - 5.7e-48 164.0 0.0 2.3e-47 162.1 0.0 2.0 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXX75424.1 - 6.3e-41 140.6 0.0 1.1e-40 139.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXX75424.1 - 1.5e-32 112.1 0.4 4.1e-32 110.7 0.2 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXX75424.1 - 1.1e-14 54.9 0.0 3e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXX75424.1 - 5.8e-14 53.3 0.0 3.5e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KXX75424.1 - 2.6e-11 43.5 0.0 2.3e-09 37.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX75424.1 - 3e-11 43.9 0.1 2.2e-10 41.1 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX75424.1 - 1e-10 41.7 0.0 2.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX75424.1 - 1.4e-09 37.7 0.0 4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXX75424.1 - 5.7e-09 36.6 2.3 5.1e-08 33.5 0.1 3.6 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX75424.1 - 3.9e-08 33.8 0.1 2.3e-07 31.3 0.1 2.5 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 KXX75424.1 - 5.4e-07 29.9 0.0 1.7e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 KXX75424.1 - 4.6e-05 23.4 0.1 0.0046 16.9 0.1 3.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX75424.1 - 5.7e-05 23.0 0.2 0.00016 21.6 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KXX75424.1 - 0.001 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KXX75424.1 - 0.0014 18.1 0.4 0.0014 18.1 0.4 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain PCMT PF01135.19 KXX75424.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FSH1 PF03959.13 KXX75425.1 - 2.1e-19 70.0 0.0 2.6e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Mannitol_dh_C PF08125.13 KXX75426.1 - 4.7e-41 140.9 0.1 7e-41 140.3 0.1 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KXX75426.1 - 1.4e-20 74.0 0.5 6.6e-20 71.8 0.1 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KXX75426.1 - 0.00032 20.3 0.8 0.0008 19.0 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXX75426.1 - 0.068 13.4 0.1 0.36 11.1 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Coatomer_WDAD PF04053.14 KXX75427.1 - 7.2e-174 579.0 0.0 1.3e-172 574.9 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KXX75427.1 - 1.2e-38 130.4 3.5 1e-06 29.3 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX75427.1 - 2.2e-08 34.3 0.1 5.4 7.4 0.0 6.2 3 3 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX75427.1 - 2.4e-07 29.8 2.0 0.015 14.0 0.0 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KXX75427.1 - 0.0035 17.4 0.1 1.7 8.7 0.0 3.9 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 KXX75427.1 - 0.084 13.1 0.2 0.39 10.9 0.0 2.1 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase CRAL_TRIO PF00650.20 KXX75428.1 - 6e-23 81.3 0.0 9.1e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXX75428.1 - 1.8e-11 44.1 0.2 3.7e-11 43.0 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.7 KXX75429.1 - 1.6e-52 177.8 0.0 1.9e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase eIF3m_C_helix PF18005.1 KXX75429.1 - 0.15 11.7 0.6 0.27 11.0 0.6 1.4 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Mod_r PF07200.13 KXX75430.1 - 3.5e-35 121.3 1.3 4.2e-35 121.0 1.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KXX75430.1 - 0.016 14.1 0.3 0.02 13.8 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SH3_9 PF14604.6 KXX75431.1 - 2.9e-29 100.7 3.3 6.1e-14 51.6 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXX75431.1 - 7.3e-27 92.7 3.8 7.8e-13 47.8 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXX75431.1 - 2.2e-16 59.3 0.0 2e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KXX75431.1 - 2.6e-16 59.5 0.0 4.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glutaredoxin PF00462.24 KXX75432.1 - 3.5e-17 62.4 0.0 1.7e-16 60.2 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KXX75432.1 - 5.6e-12 45.6 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KXX75432.1 - 0.11 12.5 0.0 0.73 9.8 0.0 2.3 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KXX75432.1 - 0.19 12.1 0.0 14 6.1 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like F-box PF00646.33 KXX75434.1 - 1.5e-06 28.0 0.2 3.6e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX75434.1 - 0.00075 19.3 0.4 0.0027 17.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like CBF PF03914.17 KXX75435.1 - 1.7e-56 190.9 0.4 3.9e-56 189.7 0.1 1.9 2 0 0 2 2 2 1 CBF/Mak21 family Mo25 PF08569.11 KXX75435.1 - 0.0039 16.6 0.1 0.0089 15.4 0.0 1.6 2 0 0 2 2 2 1 Mo25-like APS_kinase PF01583.20 KXX75436.1 - 7.7e-71 237.1 0.0 1.4e-70 236.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase 4HBT PF03061.22 KXX75436.1 - 1.6e-09 38.0 0.0 3.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily AAA_33 PF13671.6 KXX75436.1 - 4.8e-05 23.5 0.0 0.00016 21.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXX75436.1 - 0.00016 22.2 0.0 0.00037 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXX75436.1 - 0.0071 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 V-ATPase_C PF03223.15 KXX75437.1 - 1e-123 413.4 0.0 1.2e-123 413.2 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Bap31_Bap29_C PF18035.1 KXX75437.1 - 0.16 12.0 1.2 4.5 7.4 0.2 2.6 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1996 PF09362.10 KXX75439.1 - 9.3e-74 248.3 0.6 1.1e-73 248.1 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) tRNA-synt_2b PF00587.25 KXX75440.1 - 2.8e-32 112.1 0.0 1.5e-31 109.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXX75440.1 - 2.8e-06 27.4 0.0 6.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TF_Zn_Ribbon PF08271.12 KXX75440.1 - 0.022 14.3 1.2 0.1 12.2 0.3 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Ccdc124 PF06244.12 KXX75441.1 - 8.7e-28 97.5 22.2 7.5e-27 94.4 22.2 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Chon_Sulph_att PF06566.11 KXX75441.1 - 1.3 8.9 7.2 1.8 8.4 7.2 1.2 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain TMEM214 PF10151.9 KXX75441.1 - 4.5 5.6 14.7 6.4 5.1 14.7 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Fungal_trans_2 PF11951.8 KXX75442.1 - 1.6e-11 43.6 1.9 4e-11 42.4 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX75442.1 - 2e-06 27.8 11.2 4.4e-06 26.7 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob1_phocein PF03637.17 KXX75443.1 - 3.8e-22 79.1 0.1 5.8e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KXX75443.1 - 0.16 12.2 4.0 0.37 11.1 4.0 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Arv1 PF04161.13 KXX75444.1 - 1.6e-34 119.9 0.7 1.7e-34 119.8 0.7 1.0 1 0 0 1 1 1 1 Arv1-like family LysM PF01476.20 KXX75445.1 - 0.0034 17.4 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain SMC_N PF02463.19 KXX75446.1 - 1e-71 240.9 0.4 5.7e-70 235.2 0.4 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXX75446.1 - 3.8e-21 75.6 0.1 3.8e-21 75.6 0.1 3.1 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXX75446.1 - 8.7e-09 35.6 9.5 0.00018 21.4 0.1 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXX75446.1 - 3.8e-05 24.3 38.2 3.8e-05 24.3 38.2 7.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 KXX75446.1 - 0.00013 21.6 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4250 PF14056.6 KXX75446.1 - 7 6.7 6.8 5.1 7.1 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4250) MOSC PF03473.17 KXX75447.1 - 2.5e-26 92.2 0.0 6e-26 91.0 0.0 1.6 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 KXX75447.1 - 1.6e-11 44.2 0.0 3.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain NOT2_3_5 PF04153.18 KXX75448.1 - 4.2e-28 98.0 0.4 6.5e-28 97.4 0.4 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.19 KXX75449.1 - 8.9e-49 165.5 0.2 1.1e-48 165.1 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXX75449.1 - 3.8e-07 29.9 0.0 8.6e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KXX75449.1 - 3.3e-05 23.9 0.1 0.36 10.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXX75449.1 - 0.0086 15.6 1.8 0.12 11.9 1.9 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX75449.1 - 0.0087 16.1 0.0 0.021 14.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KXX75449.1 - 0.013 14.5 0.9 2.5 7.0 0.1 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KXX75449.1 - 0.014 15.9 0.0 0.032 14.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX75449.1 - 0.016 15.6 0.0 0.058 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 KXX75449.1 - 0.034 13.4 0.4 6.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 KXX75449.1 - 0.042 13.6 0.2 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXX75449.1 - 0.061 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXX75449.1 - 0.099 13.2 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXX75449.1 - 0.099 12.4 0.2 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX75449.1 - 0.1 12.9 0.1 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXX75449.1 - 0.12 12.2 1.3 1.3 8.7 1.3 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KXX75449.1 - 0.13 12.0 0.2 6.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 KXX75449.1 - 0.14 11.2 0.1 0.32 10.0 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein CUE PF02845.16 KXX75451.1 - 2.3e-07 30.4 0.0 3.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 KXX75451.1 - 0.18 11.9 1.7 0.37 10.9 1.7 1.5 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 G2BR PF18442.1 KXX75451.1 - 1.7 8.3 10.2 3.5 7.4 10.2 1.5 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) WD40 PF00400.32 KXX75452.1 - 3.1e-16 59.4 18.3 0.022 15.6 0.6 6.7 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX75452.1 - 5.4e-05 23.4 0.0 0.69 10.3 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 KXX75453.1 - 7.5e-44 149.6 0.2 1.9e-43 148.2 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX75453.1 - 1.4e-23 83.4 1.9 7.8e-21 74.5 0.1 4.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXX75453.1 - 0.0062 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXX75453.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXX75453.1 - 0.038 14.3 0.1 0.15 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.26 KXX75454.1 - 4.3e-11 42.6 0.0 6.7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPPII_N PF12583.8 KXX75454.1 - 9.7 6.8 8.3 9.8 6.8 0.4 2.3 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal 2OG-FeII_Oxy_2 PF13532.6 KXX75455.1 - 3.8e-38 131.7 0.0 4.9e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KXX75455.1 - 2.5e-09 37.1 3.2 4.3e-09 36.3 3.2 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 KXX75455.1 - 7.4e-05 22.4 0.1 0.00015 21.4 0.1 1.5 1 0 0 1 1 1 1 CUE domain p450 PF00067.22 KXX75456.1 - 8.7e-48 163.2 0.0 1.2e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2268 PF10026.9 KXX75456.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) MutS_V PF00488.21 KXX75457.1 - 2.5e-66 223.3 0.1 4.5e-66 222.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXX75457.1 - 9.5e-40 136.9 0.1 1.8e-39 135.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXX75457.1 - 4.4e-30 104.2 0.0 2.1e-29 102.0 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KXX75457.1 - 1.9e-15 57.4 0.0 4.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXX75457.1 - 1.1e-10 41.7 0.2 3.7e-10 40.0 0.1 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA_23 PF13476.6 KXX75457.1 - 0.0078 16.7 2.4 0.0084 16.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXX75457.1 - 0.033 14.0 0.2 0.1 12.4 0.2 1.9 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXX75457.1 - 0.039 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3461 PF11944.8 KXX75457.1 - 0.055 13.6 0.4 0.12 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) AAA_27 PF13514.6 KXX75457.1 - 0.08 12.5 0.5 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain HET PF06985.11 KXX75458.1 - 3.8e-34 118.1 0.1 6.6e-34 117.4 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RIO1 PF01163.22 KXX75459.1 - 1e-05 25.3 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KXX75459.1 - 4.8e-05 23.4 0.0 5.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DMP12 PF16779.5 KXX75459.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.4 2 0 0 2 2 2 0 DNA-mimic protein Pkinase PF00069.25 KXX75459.1 - 0.09 12.1 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Fungal_trans PF04082.18 KXX75460.1 - 5.8e-07 28.8 0.0 4.5e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.20 KXX75461.1 - 2.1e-164 547.3 0.0 2.6e-164 547.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXX75461.1 - 1.2e-08 35.1 0.1 2.2e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXX75461.1 - 8.2e-06 26.2 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Epimerase PF01370.21 KXX75462.1 - 2.8e-17 63.0 0.0 4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX75462.1 - 2e-11 43.9 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXX75462.1 - 1.5e-07 30.7 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXX75462.1 - 2.7e-05 23.5 0.0 8.8e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KXX75462.1 - 0.18 11.3 0.7 1.4 8.3 0.1 2.3 2 1 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.16 KXX75463.1 - 1e-32 113.5 26.2 1e-32 113.5 26.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4079 PF13301.6 KXX75463.1 - 0.47 10.6 0.0 0.47 10.6 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) SLATT_1 PF18181.1 KXX75463.1 - 0.98 9.4 2.8 6.6 6.7 0.5 2.8 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4231 PF14015.6 KXX75463.1 - 5.8 7.4 7.9 2.5 8.6 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) SUR7 PF06687.12 KXX75464.1 - 0.00065 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 SUR7/PalI family HET PF06985.11 KXX75465.1 - 1.5e-19 70.8 0.0 3.8e-19 69.5 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HSP20 PF00011.21 KXX75466.1 - 1.5e-19 70.0 0.0 7.5e-13 48.5 0.0 2.7 3 0 0 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXX75466.1 - 9.3e-05 21.9 0.0 0.024 14.2 0.0 2.6 3 0 0 3 3 3 2 HSP20-like domain found in ArsA Alpha_GJ PF03229.13 KXX75466.1 - 0.29 11.7 13.2 0.55 10.8 13.2 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J Fer4 PF00037.27 KXX75468.1 - 4.3e-14 51.6 16.4 5.9e-08 32.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXX75468.1 - 5.7e-13 49.2 10.7 8.9e-13 48.6 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXX75468.1 - 7.3e-11 42.8 6.9 7.6e-05 23.6 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KXX75468.1 - 3.9e-10 39.7 4.7 7.5e-05 22.8 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXX75468.1 - 3.7e-09 36.5 21.0 8.2e-07 29.0 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXX75468.1 - 2.1e-08 34.2 10.1 4.2e-08 33.2 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXX75468.1 - 3.5e-07 30.6 19.5 9.3e-05 22.8 11.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXX75468.1 - 7.1e-07 29.0 16.9 0.00021 21.2 5.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KXX75468.1 - 9.5e-07 28.6 12.2 0.0028 17.6 3.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KXX75468.1 - 2.1e-05 24.6 11.6 0.00067 20.0 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXX75468.1 - 0.00012 22.5 12.0 0.022 15.3 13.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KXX75468.1 - 0.0061 16.8 5.5 0.76 10.1 0.5 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KXX75468.1 - 0.033 14.4 9.3 0.51 10.6 1.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KXX75468.1 - 0.046 13.9 4.9 0.24 11.6 0.3 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 KXX75468.1 - 0.081 13.5 14.8 0.82 10.3 4.0 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KXX75468.1 - 0.089 13.8 16.6 0.41 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain EPF PF17181.4 KXX75468.1 - 0.42 10.6 5.8 0.18 11.9 0.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 KXX75468.1 - 0.46 11.3 11.9 3.4 8.6 2.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain PP-binding PF00550.25 KXX75469.1 - 3.5e-12 46.5 0.1 4.6e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXX75469.1 - 4.1e-05 23.7 0.2 5.2e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.24 KXX75470.1 - 9.9e-11 41.3 8.3 1.8e-05 24.5 2.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXX75470.1 - 2e-10 40.2 11.9 2.5e-05 23.9 3.7 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXX75470.1 - 5.8e-10 38.9 17.4 8.7e-05 22.4 4.2 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KXX75470.1 - 1.1e-08 35.7 6.3 0.00012 22.7 0.3 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KXX75470.1 - 6e-06 26.5 1.2 1.2e-05 25.4 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXX75470.1 - 0.051 14.1 18.2 0.87 10.2 6.4 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Fringe PF02434.16 KXX75471.1 - 1.3e-07 31.3 0.6 1.3e-06 28.1 0.6 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KXX75471.1 - 0.0015 18.4 3.4 0.0043 16.9 3.4 1.7 1 0 0 1 1 1 1 PAN domain Glyco_tranf_2_3 PF13641.6 KXX75472.1 - 2.3e-10 40.7 0.1 4.9e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KXX75472.1 - 6e-09 36.1 9.2 2.5e-08 34.1 9.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KXX75472.1 - 4.2e-08 32.9 0.1 8.6e-08 31.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KXX75472.1 - 1.4e-05 23.9 0.5 0.00028 19.7 0.5 2.3 1 1 0 1 1 1 1 Chitin synthase HRXXH PF13933.6 KXX75473.1 - 5.2e-69 232.5 0.2 5.7e-69 232.4 0.2 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KXX75473.1 - 4e-05 24.2 0.1 5.3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF423 PF04241.15 KXX75474.1 - 4.2e-19 68.6 3.1 1e-17 64.1 3.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF423) Abhydrolase_6 PF12697.7 KXX75476.1 - 2.7e-08 34.7 4.2 4.3e-08 34.0 4.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX75476.1 - 2.4e-06 27.4 0.2 4.6e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX75476.1 - 0.0062 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KXX75476.1 - 0.008 16.3 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DUF1057 PF06342.12 KXX75476.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) p450 PF00067.22 KXX75477.1 - 2.4e-50 171.7 0.0 3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ScsC_N PF18312.1 KXX75477.1 - 0.029 14.2 1.5 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain GMC_oxred_N PF00732.19 KXX75478.1 - 1.6e-60 205.0 0.0 2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX75478.1 - 4.4e-05 24.0 0.0 0.00013 22.5 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXX75478.1 - 0.00036 19.7 0.0 0.0028 16.8 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KXX75478.1 - 0.00038 19.8 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXX75478.1 - 0.0041 16.8 0.1 0.059 12.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX75478.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXX75478.1 - 0.016 15.2 0.1 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXX75478.1 - 0.041 12.9 0.0 0.041 12.9 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.14 KXX75478.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXX75478.1 - 0.12 12.6 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KXX75478.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase But2 PF09792.9 KXX75479.1 - 0.0003 21.2 0.1 0.00065 20.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain FAD_binding_4 PF01565.23 KXX75480.1 - 4.9e-24 84.7 0.2 8.3e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX75480.1 - 6.3e-05 23.0 0.2 0.00017 21.6 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_2 PF02230.16 KXX75482.1 - 8.7e-21 74.7 0.0 2.7e-19 69.8 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KXX75482.1 - 0.006 16.3 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXX75482.1 - 0.013 16.2 3.2 0.53 10.8 1.0 2.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXX75482.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family HA2 PF04408.23 KXX75483.1 - 1.3e-22 80.1 3.0 1.6e-22 79.8 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXX75483.1 - 2.5e-22 79.0 0.0 6.3e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXX75483.1 - 3.3e-13 49.9 0.0 1e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KXX75483.1 - 4.4e-12 46.2 0.7 1e-11 45.0 0.7 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KXX75483.1 - 6.7e-06 26.0 1.2 2.3e-05 24.2 1.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXX75483.1 - 1.3e-05 25.5 0.1 4.5e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXX75483.1 - 0.00011 21.4 0.0 0.00024 20.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXX75483.1 - 0.00044 20.0 0.4 0.0012 18.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXX75483.1 - 0.0078 16.6 0.9 0.016 15.6 0.3 1.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KXX75483.1 - 0.03 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KXX75483.1 - 0.033 14.2 0.5 0.29 11.2 0.5 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KXX75483.1 - 0.065 12.7 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KXX75483.1 - 0.074 13.4 0.0 0.31 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXX75483.1 - 0.09 13.3 0.3 0.56 10.7 0.3 2.4 1 1 0 1 1 1 0 ABC transporter Microtub_bd PF16796.5 KXX75483.1 - 0.1 12.5 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding Herpes_ori_bp PF02399.15 KXX75483.1 - 0.14 10.2 0.1 0.19 9.7 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_25 PF13481.6 KXX75483.1 - 0.14 11.7 0.0 0.38 10.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXX75483.1 - 0.17 12.1 0.9 0.68 10.1 0.2 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KXX75483.1 - 0.22 11.9 0.5 0.9 10.0 0.2 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.21 KXX75484.1 - 2.5e-59 200.0 0.0 2.8e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 KXX75484.1 - 6.3e-07 29.6 0.0 1.1e-05 25.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXX75484.1 - 0.00016 22.2 0.2 0.00072 20.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX75484.1 - 0.0035 17.6 0.0 0.008 16.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX75484.1 - 0.0057 17.1 0.0 0.0061 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXX75484.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 KXX75484.1 - 0.023 14.9 0.0 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXX75484.1 - 0.026 14.6 0.0 0.059 13.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase dNK PF01712.19 KXX75484.1 - 0.029 14.2 0.1 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 KXX75484.1 - 0.054 14.0 0.0 0.071 13.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 KXX75484.1 - 0.17 12.3 0.3 0.77 10.2 0.3 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TENA_THI-4 PF03070.16 KXX75486.1 - 5.8e-07 29.5 0.0 3.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 TENA/THI-4/PQQC family QRPTase_N PF02749.16 KXX75486.1 - 0.051 13.6 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain FMO-like PF00743.19 KXX75487.1 - 4.4e-10 38.6 0.1 7.3e-10 37.9 0.1 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXX75487.1 - 3.1e-09 36.4 0.0 4.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXX75487.1 - 6.2e-08 32.2 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX75487.1 - 6.8e-05 22.2 0.0 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.6 KXX75488.1 - 2.1e-15 56.5 0.0 4.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Nuf2 PF03800.14 KXX75488.1 - 0.025 14.7 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Nuf2 family BAG6 PF12057.8 KXX75488.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 BCL2-associated athanogene 6 Sas10 PF09368.10 KXX75489.1 - 0.22 12.0 2.5 0.48 10.9 1.6 2.0 2 0 0 2 2 2 0 Sas10 C-terminal domain ALO PF04030.14 KXX75490.1 - 4.7e-17 62.7 0.0 7.6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KXX75490.1 - 4.2e-15 55.7 0.2 8.4e-15 54.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FPN1 PF06963.12 KXX75491.1 - 9.4e-117 390.2 13.1 1.1e-116 390.0 13.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Transgly_assoc PF04226.13 KXX75491.1 - 0.34 11.2 4.8 11 6.3 0.5 3.7 3 0 0 3 3 3 0 Transglycosylase associated protein Glyco_hydro_76 PF03663.14 KXX75492.1 - 2.2e-125 419.0 1.0 2.6e-125 418.8 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TBP PF00352.21 KXX75493.1 - 2e-58 194.3 0.2 6e-29 99.8 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KXX75493.1 - 7.5e-07 29.2 0.0 0.039 14.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Sugar_tr PF00083.24 KXX75494.1 - 3.5e-72 243.7 19.4 4.3e-72 243.4 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX75494.1 - 1.9e-26 92.9 26.4 2.3e-22 79.4 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FUSC_2 PF13515.6 KXX75494.1 - 8 6.6 14.7 0.037 14.1 2.6 3.0 3 0 0 3 3 3 0 Fusaric acid resistance protein-like HET PF06985.11 KXX75495.1 - 3.6e-30 105.3 0.0 5.2e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 KXX75495.1 - 2.3e-06 27.6 1.8 1.8e-05 24.7 0.6 3.0 2 0 0 2 2 2 1 WW domain Cupin_8 PF13621.6 KXX75497.1 - 5.3e-36 124.6 0.0 9.1e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KXX75497.1 - 1.1e-17 64.5 0.0 1.8e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KXX75497.1 - 2.9e-16 59.2 5.9 2.9e-10 40.0 0.1 4.0 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KXX75497.1 - 7.5e-08 32.4 2.4 0.011 16.0 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 KXX75497.1 - 0.00026 21.2 3.6 0.0077 16.5 0.0 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KXX75497.1 - 0.00045 20.1 0.5 0.047 13.7 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 KXX75497.1 - 0.018 14.6 0.3 0.93 9.1 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Cupin_4 PF08007.12 KXX75497.1 - 0.027 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Kelch_2 PF07646.15 KXX75497.1 - 0.031 14.2 6.6 1.3 9.1 0.1 3.5 4 0 0 4 4 4 0 Kelch motif Mito_carr PF00153.27 KXX75498.1 - 9.7e-45 150.4 9.2 1.9e-17 62.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF236 PF03057.14 KXX75500.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 DUF236 repeat RGS PF00615.19 KXX75501.1 - 2.3e-09 37.6 0.0 3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.19 KXX75502.1 - 2.7e-18 66.6 0.0 4.7e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HSD3 PF15244.6 KXX75502.1 - 0.044 13.3 0.3 0.09 12.3 0.3 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 PAP_central PF04928.17 KXX75502.1 - 0.12 11.4 0.1 0.32 10.0 0.1 1.7 2 0 0 2 2 2 0 Poly(A) polymerase central domain HDNR PF15115.6 KXX75503.1 - 0.048 13.9 0.1 0.053 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function with conserved HDNR motif AAA PF00004.29 KXX75505.1 - 7.6e-36 123.5 0.0 1.5e-35 122.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX75505.1 - 6.3e-08 32.3 0.6 1.5e-07 31.1 0.6 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXX75505.1 - 9.2e-06 26.1 0.6 0.0002 21.8 0.6 2.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXX75505.1 - 1.7e-05 24.6 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KXX75505.1 - 6.5e-05 22.7 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXX75505.1 - 0.00026 21.3 0.2 0.021 15.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KXX75505.1 - 0.00072 19.6 0.0 0.0021 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KXX75505.1 - 0.0018 18.4 0.0 0.0036 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX75505.1 - 0.0049 16.9 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXX75505.1 - 0.0071 15.6 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KXX75505.1 - 0.0089 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXX75505.1 - 0.0092 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KXX75505.1 - 0.012 15.1 0.0 0.099 12.0 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 KXX75505.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KXX75505.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KXX75505.1 - 0.035 14.4 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_28 PF13521.6 KXX75505.1 - 0.037 14.3 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 KXX75505.1 - 0.039 13.4 0.1 0.71 9.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activat PF00158.26 KXX75505.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KXX75505.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXX75505.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 KXX75505.1 - 0.16 11.4 0.2 0.36 10.2 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 KXX75505.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KXX75505.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 KXX75505.1 - 0.19 11.5 0.0 0.78 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KXX75505.1 - 0.24 10.4 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DAO PF01266.24 KXX75506.1 - 3.1e-50 171.7 0.0 4.4e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KXX75506.1 - 9.5e-45 151.5 0.1 1.7e-44 150.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KXX75506.1 - 1.8e-06 27.3 2.4 1.2e-05 24.6 2.4 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXX75506.1 - 0.00021 20.8 0.6 0.00056 19.4 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX75506.1 - 0.0006 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX75506.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX75506.1 - 0.003 17.7 0.3 0.003 17.7 0.3 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXX75506.1 - 0.0097 14.7 0.9 0.015 14.1 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXX75506.1 - 0.019 15.5 0.3 0.054 14.1 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXX75506.1 - 0.021 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KXX75506.1 - 0.039 13.2 0.2 0.09 12.0 0.2 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KXX75506.1 - 0.041 13.0 0.1 0.088 11.9 0.2 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXX75506.1 - 0.046 12.9 0.1 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain LRV PF01816.17 KXX75507.1 - 0.0088 16.4 2.0 3.1 8.4 0.2 3.5 2 0 0 2 2 2 2 Leucine rich repeat variant Mus7 PF09462.10 KXX75508.1 - 3.4e-187 624.1 0.0 4.9e-187 623.5 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family COX4 PF02936.14 KXX75509.1 - 1.7e-50 170.6 0.3 1.9e-50 170.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 KXX75509.1 - 0.16 12.4 0.5 0.25 11.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Glyco_hydro_125 PF06824.11 KXX75510.1 - 8.3e-149 496.0 0.0 9.5e-149 495.8 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Usp PF00582.26 KXX75511.1 - 3.9e-24 85.8 5.2 1.9e-22 80.3 1.9 2.7 2 1 0 2 2 2 1 Universal stress protein family Ribosomal_S7 PF00177.21 KXX75512.1 - 9e-25 87.1 0.0 1.3e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Mito_fiss_reg PF05308.11 KXX75512.1 - 0.27 11.3 7.6 1 9.4 5.5 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_hydro_92 PF07971.12 KXX75513.1 - 3.5e-143 477.9 0.0 4.3e-143 477.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXX75513.1 - 2.3e-64 217.5 0.5 3.5e-64 217.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain HECT PF00632.25 KXX75514.1 - 2.6e-82 276.8 0.0 3.9e-82 276.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KXX75514.1 - 0.022 14.5 6.1 0.059 13.2 6.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif OrfB_IS605 PF01385.19 KXX75514.1 - 0.24 11.6 4.4 0.81 9.9 4.4 1.9 1 0 0 1 1 1 0 Probable transposase RRM_1 PF00076.22 KXX75515.1 - 2.2e-81 267.7 8.0 1.7e-21 75.8 0.3 5.7 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KXX75515.1 - 2.1e-27 95.1 2.2 9.5e-27 93.0 2.1 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KXX75515.1 - 6.2e-09 35.5 0.0 0.063 12.9 0.0 5.1 2 1 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXX75515.1 - 4.5e-08 32.8 0.0 0.00023 21.0 0.0 4.2 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXX75515.1 - 6.8e-06 26.0 0.9 7.3 6.7 0.0 4.8 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KXX75515.1 - 1.3e-05 25.2 0.5 0.73 10.0 0.0 5.4 5 0 0 5 5 5 1 RNA recognition motif YflT PF11181.8 KXX75515.1 - 0.007 16.9 6.3 0.15 12.5 0.4 3.5 3 0 0 3 3 3 1 Heat induced stress protein YflT CbiG_mid PF11761.8 KXX75515.1 - 0.014 15.5 0.1 40 4.4 0.0 3.7 4 0 0 4 4 4 0 Cobalamin biosynthesis central region DHHA1 PF02272.19 KXX75515.1 - 0.051 14.0 7.1 1.6 9.2 0.2 3.2 3 0 0 3 3 3 0 DHHA1 domain OB_RNB PF08206.11 KXX75515.1 - 0.09 12.5 1.7 13 5.6 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Nefa_Nip30_N PF10187.9 KXX75515.1 - 0.14 12.5 0.1 0.14 12.5 0.1 3.8 5 0 0 5 5 4 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3408 PF11888.8 KXX75515.1 - 8.1 6.6 9.7 0.16 12.1 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) AAA_13 PF13166.6 KXX75516.1 - 0.02 13.6 0.1 0.028 13.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain Glyco_hydro_125 PF06824.11 KXX75517.1 - 5.6e-07 28.8 0.1 7e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) RCC1 PF00415.18 KXX75518.1 - 1.1e-24 86.7 0.5 1.8e-08 34.8 0.2 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KXX75518.1 - 3.9e-11 43.3 0.1 9.2e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 KXX75518.1 - 1e-07 31.5 9.4 9e-07 28.5 0.5 4.6 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KXX75518.1 - 8.4e-07 29.5 0.1 3.3e-06 27.6 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX75518.1 - 5.1e-06 26.4 0.1 0.1 13.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXX75518.1 - 0.013 15.8 0.1 0.16 12.3 0.1 3.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) DUF2480 PF10652.9 KXX75518.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) PTPA PF03095.15 KXX75519.1 - 5.5e-103 344.5 0.0 8.3e-82 275.0 0.0 2.0 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein SET PF00856.28 KXX75520.1 - 0.013 15.8 0.0 0.12 12.7 0.0 2.2 1 1 0 1 1 1 0 SET domain Rad4 PF03835.15 KXX75521.1 - 6.6e-29 100.5 0.0 1.6e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXX75521.1 - 4.7e-28 97.4 0.3 9.7e-28 96.4 0.3 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KXX75521.1 - 3.1e-22 78.2 0.0 6.5e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KXX75521.1 - 4.5e-15 56.4 0.6 4.5e-15 56.4 0.6 4.1 3 2 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KXX75521.1 - 0.0014 19.0 0.2 0.0064 16.9 0.1 2.2 2 1 0 2 2 2 1 Transglutaminase-like superfamily DUF5132 PF17195.4 KXX75521.1 - 1.8 8.7 5.6 1.7 8.8 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) HET PF06985.11 KXX75522.1 - 1.3e-36 126.2 0.1 2.6e-36 125.2 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 KXX75523.1 - 1.8e-18 67.2 0.0 3.3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX75523.1 - 9.3e-05 22.6 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX75523.1 - 0.00023 21.5 0.1 0.0025 18.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 KXX75523.1 - 0.0011 18.6 0.0 0.0038 16.9 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 KXX75523.1 - 0.0083 16.5 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXX75523.1 - 0.0096 16.5 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX75523.1 - 0.018 15.1 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KXX75523.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 KXX75523.1 - 0.036 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KXX75523.1 - 0.05 13.2 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.27 KXX75524.1 - 6.1e-65 215.2 3.5 5.8e-24 83.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pept_tRNA_hydro PF01195.19 KXX75524.1 - 0.05 13.6 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase Tim17 PF02466.19 KXX75524.1 - 0.14 12.6 4.0 0.21 12.0 1.6 2.7 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family zf-CCCH PF00642.24 KXX75525.1 - 0.0017 18.2 4.9 0.0017 18.2 4.9 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXX75525.1 - 0.36 10.7 25.4 0.043 13.6 4.0 3.4 3 1 0 3 3 3 0 CCCH-type zinc finger NACHT_N PF17100.5 KXX75527.1 - 1.5e-07 31.5 0.1 2.4e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT_N PF17100.5 KXX75528.1 - 1.4e-53 182.0 0.6 3.4e-53 180.7 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 KXX75528.1 - 8.8e-30 103.1 4.1 1.2e-14 54.6 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXX75528.1 - 8.7e-26 89.2 9.0 8.4e-07 29.2 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KXX75528.1 - 1e-22 80.2 5.2 4.9e-11 42.9 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75528.1 - 1.4e-19 68.1 5.3 9.4e-05 22.5 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXX75528.1 - 2.6e-19 69.0 11.3 3.6e-09 36.7 0.2 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.12 KXX75528.1 - 9.3e-07 28.9 0.1 4.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX75528.1 - 3.4e-05 24.3 0.1 0.00023 21.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX75528.1 - 0.017 15.4 0.0 0.076 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain GLTP PF08718.11 KXX75528.1 - 0.054 13.8 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) AAA_14 PF13173.6 KXX75528.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KXX75529.1 - 4.3e-21 75.1 0.0 7.8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 KXX75530.1 - 7.6e-26 90.5 3.0 7.6e-26 90.5 3.0 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXX75530.1 - 1.1e-10 41.5 0.5 2.7e-10 40.2 0.3 1.8 2 0 0 2 2 2 1 Berberine and berberine like Gly_transf_sug PF04488.15 KXX75531.1 - 1.3e-10 41.8 0.1 2.7e-10 40.7 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif NicO PF03824.16 KXX75534.1 - 2.5e-68 230.5 4.4 3.4e-68 230.1 4.4 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein UDPG_MGDP_dh_N PF03721.14 KXX75535.1 - 1.7e-50 171.2 0.1 3.5e-35 121.3 0.0 2.6 2 1 1 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXX75535.1 - 6.7e-28 96.7 0.0 1.5e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXX75535.1 - 9.9e-23 80.6 0.0 2e-17 63.5 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 KXX75535.1 - 0.016 15.4 0.2 0.29 11.3 0.2 2.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXX75535.1 - 0.12 12.9 0.1 5 7.8 0.1 3.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HET PF06985.11 KXX75536.1 - 8.9e-15 55.3 0.0 9e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) CorA PF01544.18 KXX75538.1 - 5.9e-15 55.3 0.1 8.9e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_10 PF00331.20 KXX75538.1 - 0.0057 15.9 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 adh_short PF00106.25 KXX75539.1 - 1.2e-19 70.5 0.0 6.3e-16 58.4 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX75539.1 - 1.4e-13 51.0 0.1 2.4e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX75539.1 - 0.001 19.0 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KXX75539.1 - 0.039 13.7 0.2 0.078 12.7 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TIP39 PF14980.6 KXX75541.1 - 0.018 14.9 0.4 0.041 13.7 0.4 1.6 1 0 0 1 1 1 0 TIP39 peptide Tho2 PF11262.8 KXX75541.1 - 0.84 8.8 3.4 1.4 8.1 3.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GH131_N PF18271.1 KXX75542.1 - 1.4e-64 218.3 1.9 1.6e-64 218.1 1.9 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain MAPEG PF01124.18 KXX75543.1 - 6.9e-16 58.3 4.0 8.7e-16 58.0 4.0 1.1 1 0 0 1 1 1 1 MAPEG family BTP PF05232.12 KXX75543.1 - 0.011 15.7 0.3 0.011 15.7 0.3 2.5 2 1 1 3 3 3 0 Chlorhexidine efflux transporter Phage_TAC_7 PF10109.9 KXX75543.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 PTPLA PF04387.14 KXX75544.1 - 1.1e-54 184.6 10.2 1.1e-54 184.6 10.2 2.0 2 1 1 3 3 3 1 Protein tyrosine phosphatase-like protein, PTPLA PAP_central PF04928.17 KXX75545.1 - 5.1e-107 356.5 0.0 6.7e-107 356.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KXX75545.1 - 1.4e-62 210.4 0.1 2.9e-62 209.3 0.1 1.6 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KXX75545.1 - 2e-08 34.4 0.0 7.4e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KXX75545.1 - 0.038 14.1 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Pyr_redox_2 PF07992.14 KXX75546.1 - 2.7e-52 177.9 0.0 3.3e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX75546.1 - 6.8e-12 45.8 0.0 1.1e-10 41.9 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX75546.1 - 8.5e-05 21.9 1.0 0.033 13.4 0.2 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 KXX75546.1 - 0.065 12.9 0.2 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Fibrinogen_aC PF12160.8 KXX75546.1 - 0.17 11.7 1.7 0.31 10.9 1.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain Na_H_Exchanger PF00999.21 KXX75548.1 - 1.4e-70 238.1 38.2 1.6e-70 237.8 38.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 KXX75548.1 - 0.029 14.1 0.1 0.029 14.1 0.1 1.8 2 0 0 2 2 2 0 PepSY-associated TM region Tubulin_3 PF14881.6 KXX75549.1 - 3e-71 238.8 0.0 5.6e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KXX75549.1 - 9.7e-43 145.2 0.0 2.4e-42 144.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KXX75549.1 - 0.0054 17.0 0.0 3.4 7.8 0.0 2.5 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain ABC_membrane PF00664.23 KXX75550.1 - 8.8e-34 117.4 5.0 8.8e-34 117.4 5.0 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXX75550.1 - 4.6e-30 104.9 0.0 1.3e-29 103.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KXX75550.1 - 7.3e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXX75550.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXX75550.1 - 0.04 13.7 0.3 0.22 11.3 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.7 KXX75550.1 - 0.12 11.3 0.0 0.47 9.3 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.6 KXX75550.1 - 0.12 12.6 1.0 1.4 9.2 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TRAM_LAG1_CLN8 PF03798.16 KXX75551.1 - 1.5e-34 119.5 20.3 1.5e-34 119.5 20.3 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KXX75551.1 - 1.7e-26 91.7 0.1 1.7e-26 91.7 0.1 2.1 2 0 0 2 2 2 1 TRAM1-like protein REV PF00424.18 KXX75551.1 - 2.5 8.2 3.7 0.51 10.4 0.2 1.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PalH PF08733.10 KXX75552.1 - 1e-112 376.4 0.0 1.2e-112 376.2 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 SH3_1 PF00018.28 KXX75554.1 - 3e-05 23.5 0.0 5.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX75554.1 - 0.045 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain PGAP1 PF07819.13 KXX75555.1 - 8.1e-05 22.4 0.1 0.00013 21.8 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXX75555.1 - 0.00034 21.3 8.1 0.00086 20.0 8.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXX75555.1 - 0.0055 16.2 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXX75555.1 - 0.0086 15.4 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXX75555.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KXX75555.1 - 0.021 14.7 0.1 0.16 11.8 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KXX75555.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 KXX75555.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_2 PF13347.6 KXX75556.1 - 3.5e-13 48.9 3.3 3.5e-13 48.9 3.3 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein PUCC PF03209.15 KXX75556.1 - 5.8e-06 25.6 0.8 5.8e-06 25.6 0.8 1.9 2 0 0 2 2 2 1 PUCC protein Wzz PF02706.15 KXX75556.1 - 0.87 9.9 0.0 0.87 9.9 0.0 2.8 3 0 0 3 3 3 0 Chain length determinant protein SET PF00856.28 KXX75558.1 - 7.9e-19 68.7 0.0 1.8e-18 67.5 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KXX75558.1 - 3.9e-07 30.8 0.4 1.3e-06 29.1 0.1 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF1997 PF09366.10 KXX75560.1 - 0.92 9.6 3.4 2.1 8.5 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1997) Peroxidase_2 PF01328.17 KXX75561.1 - 1.3e-44 153.0 0.0 1.8e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 HAT_KAT11 PF08214.11 KXX75562.1 - 3.1e-90 303.0 0.0 3.9e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.6 KXX75563.1 - 1.9e-32 112.1 0.0 5.2e-32 110.7 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXX75563.1 - 0.0021 18.7 0.0 0.0056 17.3 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Maf_N PF08383.11 KXX75566.1 - 0.17 11.7 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Maf N-terminal region NMT1 PF09084.11 KXX75567.1 - 3.5e-13 50.0 0.0 6.2e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 KXX75567.1 - 4.5e-06 26.3 0.0 6.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 KXX75567.1 - 7.8e-06 25.5 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 KXX75567.1 - 0.0027 17.3 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein MRP-L28 PF09812.9 KXX75567.1 - 0.088 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 FRG1 PF06229.12 KXX75568.1 - 2.1e-52 177.6 0.3 3.4e-52 176.9 0.3 1.3 1 0 0 1 1 1 1 FRG1-like domain SRF-TF PF00319.18 KXX75569.1 - 1.3e-22 79.0 0.3 2e-22 78.4 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FeS_assembly_P PF01883.19 KXX75570.1 - 1.9e-08 34.4 0.0 7e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Fungal_trans PF04082.18 KXX75571.1 - 1.3e-08 34.2 0.0 1.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EFTUD2 PF16004.5 KXX75572.1 - 6.9e-37 126.7 8.1 1.3e-36 125.9 8.1 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU PF00009.27 KXX75572.1 - 2.3e-32 112.1 0.0 3e-30 105.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXX75572.1 - 1.2e-24 86.3 0.0 2.5e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXX75572.1 - 1.8e-18 66.3 0.0 5.4e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXX75572.1 - 5e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXX75572.1 - 1e-06 28.7 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXX75572.1 - 0.033 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Thiolase_N PF00108.23 KXX75573.1 - 3.8e-88 295.2 1.7 6.4e-88 294.5 1.7 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX75573.1 - 6.5e-46 155.0 0.5 1.5e-45 153.8 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXX75573.1 - 0.00064 19.4 0.8 0.0016 18.1 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXX75573.1 - 0.42 10.5 4.8 2.1 8.3 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.32 KXX75574.1 - 2.8e-10 40.6 0.5 0.18 12.7 0.0 5.3 4 1 1 5 5 5 3 WD domain, G-beta repeat FAD_binding_2 PF00890.24 KXX75576.1 - 2.1e-85 287.3 0.8 2.6e-85 287.0 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KXX75576.1 - 8e-22 77.2 0.1 1.5e-20 73.1 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KXX75576.1 - 1.2e-13 51.4 0.3 2.2e-13 50.6 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXX75576.1 - 1.8e-09 37.4 0.8 9.1e-09 35.2 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX75576.1 - 6.4e-09 35.9 1.9 1.6e-07 31.4 0.6 3.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX75576.1 - 5.5e-07 29.1 0.5 5.5e-06 25.8 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX75576.1 - 8.5e-06 24.7 1.7 0.0078 15.0 0.1 3.3 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 KXX75576.1 - 1.7e-05 24.2 0.0 0.091 12.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX75576.1 - 0.0002 20.8 0.8 0.00043 19.7 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXX75576.1 - 0.00025 20.4 0.7 0.036 13.3 0.3 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KXX75576.1 - 0.00028 20.1 1.8 0.13 11.3 1.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXX75576.1 - 0.0027 17.1 0.7 0.29 10.4 0.2 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DUF3914 PF13053.6 KXX75576.1 - 0.015 15.6 0.5 0.14 12.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) AlaDh_PNT_C PF01262.21 KXX75576.1 - 0.04 13.2 0.8 0.074 12.3 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXX75576.1 - 0.14 12.7 4.7 4.1 8.0 1.5 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KXX75577.1 - 2.4e-124 415.7 17.8 2.8e-124 415.4 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX75577.1 - 5.1e-25 88.1 58.0 7e-24 84.4 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Chromate_transp PF02417.15 KXX75578.1 - 1.1e-46 158.8 39.2 3.5e-35 121.5 11.6 3.8 3 1 1 4 4 4 3 Chromate transporter DUF1180 PF06679.12 KXX75578.1 - 0.0041 17.5 2.4 0.0075 16.7 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Sin3a_C PF16879.5 KXX75579.1 - 4e-75 253.2 7.8 4.7e-75 253.0 5.8 2.2 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 KXX75579.1 - 2.5e-42 142.8 4.0 4.4e-18 65.2 3.2 3.8 3 1 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KXX75579.1 - 3.6e-38 129.6 0.0 9.2e-38 128.3 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Pollen_allerg_1 PF01357.21 KXX75579.1 - 0.0058 16.6 0.3 0.16 12.0 0.5 2.4 2 0 0 2 2 2 1 Pollen allergen HEPN PF05168.14 KXX75579.1 - 0.0091 16.1 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 HEPN domain Lge1 PF11488.8 KXX75579.1 - 0.046 13.9 1.5 0.22 11.7 0.5 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 TSP_NTD PF17804.1 KXX75579.1 - 0.37 11.0 9.6 0.37 11.0 0.5 3.1 3 0 0 3 3 3 0 Tail specific protease N-terminal domain Glyco_hydro_31 PF01055.26 KXX75580.1 - 4e-140 467.9 2.5 5.1e-140 467.5 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXX75580.1 - 3.6e-33 114.2 0.0 5.8e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Rotavirus_VP7 PF05868.11 KXX75580.1 - 0.0092 15.4 0.2 0.015 14.7 0.2 1.3 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 FAP PF07174.11 KXX75580.1 - 5.4 6.4 11.3 4.8 6.6 5.6 2.3 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) DUF4448 PF14610.6 KXX75581.1 - 9.2e-40 136.4 0.1 2.5e-39 135.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) 2OG-FeII_Oxy PF03171.20 KXX75582.1 - 0.042 14.3 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXX75582.1 - 0.15 12.8 0.0 0.27 12.0 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Synapsin_N PF10581.9 KXX75582.1 - 0.3 11.1 2.0 1.6 8.7 0.3 2.4 2 0 0 2 2 2 0 Synapsin N-terminal NAD_binding_2 PF03446.15 KXX75583.1 - 1.8e-30 106.2 0.1 2.3e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXX75583.1 - 2.2e-08 34.4 0.4 4.1e-08 33.5 0.4 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXX75583.1 - 0.00038 21.0 0.0 0.0019 18.8 0.0 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KXX75583.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KXX75583.1 - 0.087 12.2 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMD PF02627.20 KXX75584.1 - 3.9e-16 58.9 0.6 3.1e-07 30.4 0.0 2.5 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family ADH_N PF08240.12 KXX75585.1 - 4.6e-16 58.7 0.0 1.8e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX75585.1 - 7e-14 51.9 0.4 1.3e-13 51.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KXX75585.1 - 0.0026 17.6 0.1 0.0043 16.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXX75585.1 - 0.17 11.8 0.7 0.62 10.0 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain GAF_2 PF13185.6 KXX75586.1 - 0.015 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 GAF domain Fungal_trans PF04082.18 KXX75586.1 - 0.023 13.7 1.0 0.095 11.7 0.1 2.3 2 1 0 2 2 2 0 Fungal specific transcription factor domain Orthoreo_P17 PF07272.11 KXX75586.1 - 0.072 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus P17 protein NAD_binding_2 PF03446.15 KXX75587.1 - 2.7e-32 112.1 0.9 4.3e-32 111.5 0.9 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXX75587.1 - 1.8e-22 79.8 0.0 4e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXX75587.1 - 0.00092 19.7 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KXX75587.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KXX75587.1 - 0.04 13.8 0.9 0.054 13.4 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXX75587.1 - 0.046 14.5 0.0 0.092 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 KXX75587.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lactamase_B PF00753.27 KXX75588.1 - 9.1e-05 22.5 2.1 0.00021 21.4 2.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXX75588.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXX75589.1 - 7.7e-07 29.3 3.0 1.7e-06 28.2 3.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily 4HBT_3 PF13622.6 KXX75590.1 - 0.037 14.3 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily p450 PF00067.22 KXX75592.1 - 1.1e-49 169.5 0.0 1.5e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAST_2 PF08368.12 KXX75593.1 - 0.0067 17.2 0.0 0.014 16.2 0.0 1.5 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 Fungal_trans_2 PF11951.8 KXX75594.1 - 2.2e-06 26.7 0.1 7.5e-06 25.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MIOX PF05153.15 KXX75595.1 - 2.1e-120 401.0 0.0 2.6e-120 400.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase NOG1_N PF17835.1 KXX75595.1 - 0.36 10.8 1.4 0.93 9.4 0.1 2.1 2 1 0 2 2 2 0 NOG1 N-terminal helical domain Sugar_tr PF00083.24 KXX75596.1 - 1.9e-80 271.0 18.9 2.2e-80 270.7 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX75596.1 - 3.3e-12 46.0 35.6 2.5e-09 36.5 26.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXX75596.1 - 5.6 5.7 18.7 0.023 13.6 6.7 2.3 2 1 0 2 2 2 0 MFS_1 like family DUF378 PF04070.12 KXX75596.1 - 6.7 6.7 9.4 8.9 6.3 0.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF378) IPP-2 PF04979.14 KXX75597.1 - 9.9e-23 81.3 10.6 9.9e-23 81.3 10.6 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) MAP65_ASE1 PF03999.12 KXX75597.1 - 2.2 6.9 6.7 0.16 10.6 0.3 1.8 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Thymidylate_kin PF02223.17 KXX75599.1 - 1.2e-41 142.5 0.0 5.8e-40 136.9 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 KXX75599.1 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KXX75599.1 - 0.002 17.7 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 KXX75599.1 - 0.012 15.4 0.0 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KXX75599.1 - 0.048 14.2 0.0 0.07 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RepB PF07506.11 KXX75602.1 - 0.077 13.1 0.9 3.5 7.7 0.0 2.9 3 0 0 3 3 3 0 RepB plasmid partitioning protein Ribosomal_L27 PF01016.19 KXX75603.1 - 2e-27 95.0 0.3 4.5e-27 93.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.6 KXX75603.1 - 0.0023 17.7 0.1 0.0044 16.8 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region TAFII28 PF04719.14 KXX75604.1 - 3.9e-22 78.1 0.0 7.2e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region GTP_cyclohydroI PF01227.22 KXX75605.1 - 9.7e-74 246.7 0.8 1.2e-73 246.3 0.8 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KXX75605.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Tub_N PF16322.5 KXX75605.1 - 0.065 13.6 6.9 0.1 13.0 6.9 1.2 1 0 0 1 1 1 0 Tubby N-terminal OmpH PF03938.14 KXX75605.1 - 0.13 12.6 0.1 1.1 9.5 0.0 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CMD PF02627.20 KXX75606.1 - 2.7e-19 69.0 0.2 4.8e-19 68.2 0.1 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family SRAP PF02586.14 KXX75607.1 - 2.1e-82 275.9 0.0 2.7e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) RNA_pol_Rpb1_1 PF04997.12 KXX75608.1 - 1.9e-81 273.8 0.0 3e-81 273.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXX75608.1 - 1.8e-78 263.7 0.4 2.7e-78 263.1 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXX75608.1 - 6.1e-72 241.2 0.0 1.4e-71 240.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXX75608.1 - 2.7e-35 121.6 0.1 1.9e-34 118.9 0.0 2.5 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXX75608.1 - 5.2e-32 110.0 0.0 1.5e-31 108.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 ADD_DNMT3 PF17980.1 KXX75610.1 - 0.036 14.1 0.4 0.073 13.1 0.4 1.4 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Orexin PF02072.15 KXX75611.1 - 0.075 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Prepro-orexin DDHD PF02862.17 KXX75613.1 - 5.1e-60 203.4 0.5 2.5e-58 197.9 0.0 2.5 2 0 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 KXX75613.1 - 0.07 12.7 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase AAR2 PF05282.11 KXX75613.1 - 0.082 12.3 0.0 0.082 12.3 0.0 2.5 2 1 1 3 3 3 0 AAR2 protein Ndc1_Nup PF09531.10 KXX75613.1 - 8.7 4.9 9.7 2 7.0 0.1 2.9 3 0 0 3 3 3 0 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 KXX75614.1 - 0.0021 18.6 0.0 0.019 15.5 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) zf-RING_2 PF13639.6 KXX75614.1 - 0.0034 17.7 4.5 0.0034 17.7 4.5 1.7 2 0 0 2 2 2 1 Ring finger domain Ank PF00023.30 KXX75614.1 - 0.047 14.2 0.0 0.81 10.3 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat zf-RING_UBOX PF13445.6 KXX75614.1 - 0.058 13.4 5.2 0.13 12.3 5.2 1.6 1 1 0 1 1 1 0 RING-type zinc-finger Cytochrome_C7 PF14522.6 KXX75614.1 - 0.13 12.3 1.2 1.5 8.9 1.8 2.0 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf-RING_4 PF14570.6 KXX75614.1 - 1.3 8.9 3.9 0.32 10.8 0.7 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXX75614.1 - 5.4 7.3 8.6 0.41 10.8 3.7 1.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Iso_dh PF00180.20 KXX75615.1 - 5e-118 394.2 0.0 5.9e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF745 PF05335.13 KXX75615.1 - 0.16 11.7 1.8 0.34 10.6 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Peptidase_S8 PF00082.22 KXX75616.1 - 7.3e-36 123.9 1.8 1.2e-35 123.2 1.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KXX75616.1 - 7.5e-27 93.2 0.6 1.6e-26 92.2 0.6 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KXX75616.1 - 0.00074 20.2 0.4 0.0023 18.7 0.4 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain Baculo_p26 PF04766.12 KXX75616.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein DUF1180 PF06679.12 KXX75616.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PX PF00787.24 KXX75617.1 - 6.6e-21 74.4 0.2 1.4e-20 73.4 0.2 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KXX75617.1 - 2.6e-14 53.4 4.1 9.9e-08 31.8 1.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KXX75617.1 - 2.7e-09 37.0 0.8 0.00074 19.2 0.7 2.2 2 0 0 2 2 2 2 BAR domain BAR_3 PF16746.5 KXX75617.1 - 0.0011 18.7 0.6 0.66 9.6 0.0 2.7 2 1 1 3 3 3 2 BAR domain of APPL family DUF3140 PF11338.8 KXX75617.1 - 0.013 15.9 1.2 0.028 14.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Sec34 PF04136.15 KXX75617.1 - 0.031 14.1 0.3 0.086 12.7 0.1 1.8 2 0 0 2 2 2 0 Sec34-like family DUF948 PF06103.11 KXX75617.1 - 0.12 12.6 2.0 3.1 8.1 0.0 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 KXX75617.1 - 0.29 11.4 5.9 3.2 8.0 1.4 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Laminin_II PF06009.12 KXX75617.1 - 0.3 11.1 1.7 0.52 10.3 0.2 2.0 2 0 0 2 2 2 0 Laminin Domain II Occludin_ELL PF07303.13 KXX75617.1 - 0.38 11.5 2.3 3.4 8.4 0.0 3.1 2 1 1 3 3 3 0 Occludin homology domain DUF3053 PF11254.8 KXX75617.1 - 0.97 9.0 3.9 2.6 7.6 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3053) DUF4795 PF16043.5 KXX75617.1 - 1 8.9 4.9 0.47 10.0 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) FlaC_arch PF05377.11 KXX75617.1 - 1.5 9.3 4.1 13 6.3 0.6 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 KXX75617.1 - 5.1 7.1 10.1 3.2 7.8 1.8 2.9 3 0 0 3 3 3 0 Prefoldin subunit Spc7 PF08317.11 KXX75617.1 - 5.1 5.9 9.6 2.1 7.1 4.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KXX75617.1 - 7.6 7.1 11.2 21 5.6 3.2 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region LETM1 PF07766.13 KXX75618.1 - 2.3e-106 355.0 1.4 2.3e-106 355.0 1.4 1.4 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KXX75618.1 - 0.00021 21.0 0.2 0.051 13.4 0.0 3.5 3 0 0 3 3 3 1 SAP domain DUF2868 PF11067.8 KXX75618.1 - 2.5 7.5 13.2 0.013 15.0 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) BPL_N PF09825.9 KXX75618.1 - 10 5.1 7.8 0.82 8.7 0.3 2.2 2 1 0 2 2 2 0 Biotin-protein ligase, N terminal ADK PF00406.22 KXX75619.1 - 4.2e-38 130.8 0.0 2.3e-20 73.2 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KXX75619.1 - 7.3e-16 57.9 0.0 1.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KXX75619.1 - 2.4e-15 57.1 0.0 6.9e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXX75619.1 - 0.00064 19.9 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXX75619.1 - 0.0024 18.4 0.0 0.027 15.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX75619.1 - 0.08 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_76 PF03663.14 KXX75620.1 - 2.5e-16 60.2 8.1 9.5e-10 38.5 0.2 3.7 3 2 0 3 3 3 2 Glycosyl hydrolase family 76 tRNA-synt_1b PF00579.25 KXX75621.1 - 1.7e-58 198.3 0.0 2.1e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Abhydrolase_1 PF00561.20 KXX75622.1 - 9.8e-11 41.8 0.0 2.2e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX75622.1 - 1.3e-08 35.7 0.0 1.7e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX75622.1 - 9.4e-06 25.1 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXX75622.1 - 9.9e-05 21.2 0.1 0.00017 20.4 0.0 1.4 2 0 0 2 2 2 1 Ndr family CH PF00307.31 KXX75623.1 - 4.5e-68 226.3 0.0 1.9e-18 66.6 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KXX75623.1 - 2.2e-05 24.8 0.2 0.00027 21.3 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXX75623.1 - 0.0013 18.1 0.2 0.61 9.8 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KXX75623.1 - 0.034 14.1 2.0 0.64 10.1 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain zf-Tim10_DDP PF02953.15 KXX75624.1 - 3.9e-17 61.6 1.7 4.5e-17 61.5 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KXX75624.1 - 0.0091 15.7 2.3 0.012 15.3 2.3 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) tRNA-synt_2 PF00152.20 KXX75625.1 - 9.6e-56 189.1 0.0 3.9e-55 187.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXX75625.1 - 2.3e-10 40.3 0.0 3.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXX75625.1 - 5.2e-06 26.1 0.1 0.0032 17.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) PH_6 PF15406.6 KXX75626.1 - 1.7e-47 160.3 4.5 1.7e-47 160.3 4.5 4.6 4 1 1 5 5 5 1 Pleckstrin homology domain PH PF00169.29 KXX75626.1 - 0.00016 22.2 0.0 0.0005 20.5 0.0 2.0 1 1 0 1 1 1 1 PH domain PH_4 PF15404.6 KXX75626.1 - 0.6 9.9 0.0 0.6 9.9 0.0 3.8 3 1 0 4 4 4 0 Pleckstrin homology domain HATPase_c PF02518.26 KXX75627.1 - 3.2e-22 79.2 0.0 6.6e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXX75627.1 - 1e-17 64.3 0.1 1.2e-13 51.2 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain PAS_4 PF08448.10 KXX75627.1 - 1.6e-08 34.8 0.0 0.00017 21.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 KXX75627.1 - 2.2e-06 27.6 1.8 3.8e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KXX75627.1 - 5.5e-06 26.4 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXX75627.1 - 2.8e-05 24.3 0.0 0.0002 21.6 0.0 2.5 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 KXX75627.1 - 0.00011 22.1 0.0 0.00062 19.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 KXX75627.1 - 0.00025 21.3 0.4 0.0022 18.3 0.1 2.3 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 KXX75627.1 - 0.067 13.5 0.0 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.6 KXX75627.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 GAF domain PG_binding_1 PF01471.18 KXX75628.1 - 0.00021 21.5 0.0 0.12 12.6 0.0 3.4 3 0 0 3 3 3 1 Putative peptidoglycan binding domain BLOC1_2 PF10046.9 KXX75628.1 - 0.048 14.0 2.2 0.15 12.4 2.2 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KXX75628.1 - 0.94 10.1 4.1 28 5.4 1.0 2.9 2 0 0 2 2 2 0 SlyX Tropomyosin_1 PF12718.7 KXX75628.1 - 1.3 9.2 10.0 0.034 14.3 1.4 2.5 3 0 0 3 3 3 0 Tropomyosin like AIM5 PF17050.5 KXX75628.1 - 1.8 9.4 5.2 11 7.0 0.1 3.3 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 Spc7 PF08317.11 KXX75628.1 - 1.9 7.3 11.0 0.028 13.3 3.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 KXX75628.1 - 3.7 6.1 4.3 1.8 7.1 1.9 1.6 2 0 0 2 2 2 0 AAA domain HMMR_N PF15905.5 KXX75628.1 - 8.7 5.7 8.2 0.43 10.0 2.2 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CLTH PF10607.9 KXX75629.1 - 8.2e-31 106.9 0.0 1.5e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KXX75629.1 - 1.1e-05 25.3 1.8 2e-05 24.5 1.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KXX75629.1 - 0.011 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_2 PF13639.6 KXX75629.1 - 0.013 15.8 2.0 0.021 15.2 2.0 1.3 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KXX75629.1 - 0.021 14.7 1.3 0.037 13.9 1.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Flagellin_C PF00700.21 KXX75629.1 - 0.03 14.7 0.1 0.063 13.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region zf-C3HC4_3 PF13920.6 KXX75629.1 - 0.058 13.3 1.3 0.098 12.5 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX75629.1 - 0.07 13.1 1.6 0.11 12.4 1.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXX75629.1 - 0.1 12.8 2.7 0.19 11.9 2.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXX75629.1 - 0.31 10.9 3.8 0.55 10.1 3.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX75629.1 - 0.43 10.5 2.9 0.76 9.7 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KXX75630.1 - 3.8e-16 58.7 0.0 6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXX75630.1 - 0.011 15.8 0.1 0.018 15.1 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KXX75630.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Clr5 PF14420.6 KXX75631.1 - 6.7e-21 74.3 0.3 1.2e-19 70.2 0.1 2.9 3 0 0 3 3 3 1 Clr5 domain Nop14 PF04147.12 KXX75631.1 - 0.0033 15.7 7.8 0.0047 15.2 7.8 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4207 PF13904.6 KXX75631.1 - 0.013 15.2 6.3 0.034 13.8 6.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) NOA36 PF06524.12 KXX75631.1 - 0.35 10.1 8.9 0.58 9.4 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KXX75631.1 - 2.3 7.9 10.5 5.5 6.7 10.5 1.6 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 KXX75631.1 - 3.8 5.7 16.6 6 5.0 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 KXX75632.1 - 2.8e-06 27.2 0.1 2.8e-06 27.2 0.1 4.2 2 2 2 4 4 4 1 PPP4R2 Spt20 PF12090.8 KXX75632.1 - 0.0039 16.8 20.4 0.0039 16.8 20.4 4.2 3 1 0 3 3 3 1 Spt20 family V_ATPase_I PF01496.19 KXX75632.1 - 0.41 8.5 1.1 0.93 7.3 1.1 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Methyltransf_34 PF11312.8 KXX75632.1 - 8.6 5.5 6.7 11 5.1 1.7 2.6 2 1 0 2 2 2 0 Putative SAM-dependent methyltransferase Amidase PF01425.21 KXX75633.1 - 3.1e-68 230.8 0.1 4.6e-68 230.2 0.1 1.3 1 0 0 1 1 1 1 Amidase Ribosomal_L2_C PF03947.18 KXX75633.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Troponin PF00992.20 KXX75634.1 - 1.1 9.5 9.1 12 6.3 4.9 2.2 2 0 0 2 2 2 0 Troponin TFIIA PF03153.13 KXX75634.1 - 1.3 8.9 5.0 2.6 8.0 5.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 KXX75635.1 - 8.5e-34 117.8 0.0 8.5e-34 117.8 0.0 8.2 1 1 4 5 5 1 1 AAA domain AAA_21 PF13304.6 KXX75635.1 - 1e-07 32.1 5.1 6.1e-05 23.0 3.5 4.2 4 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXX75635.1 - 1.7e-07 31.3 24.2 6.7e-07 29.3 3.4 5.8 1 1 1 4 4 3 2 AAA ATPase domain SMC_N PF02463.19 KXX75635.1 - 4e-07 29.7 0.0 4e-07 29.7 0.0 3.2 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KXX75635.1 - 1.4e-06 28.5 0.0 4.5e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXX75635.1 - 0.0016 18.2 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad50_zn_hook PF04423.14 KXX75635.1 - 0.012 15.4 0.9 0.012 15.4 0.9 6.6 4 2 2 6 6 5 0 Rad50 zinc hook motif AAA_16 PF13191.6 KXX75635.1 - 0.06 13.7 0.0 0.06 13.7 0.0 5.7 4 2 1 5 5 3 0 AAA ATPase domain ABC_tran PF00005.27 KXX75635.1 - 0.069 13.7 0.0 0.069 13.7 0.0 7.5 4 3 0 4 4 2 0 ABC transporter DUF948 PF06103.11 KXX75635.1 - 0.48 10.7 31.5 0.17 12.2 0.2 7.3 7 1 0 7 7 7 0 Bacterial protein of unknown function (DUF948) AAA_19 PF13245.6 KXX75635.1 - 8.5 6.7 9.3 1.9 8.8 0.0 4.1 4 1 0 4 4 4 0 AAA domain DUF1772 PF08592.11 KXX75636.1 - 0.0024 18.2 9.5 0.0079 16.5 0.3 3.3 2 2 0 3 3 3 2 Domain of unknown function (DUF1772) CRPA PF05745.11 KXX75636.1 - 0.11 12.5 6.1 0.66 10.0 0.2 3.2 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) FAD-oxidase_C PF02913.19 KXX75637.1 - 2.1e-60 204.5 0.1 3.5e-60 203.7 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXX75637.1 - 2.2e-37 127.9 0.0 4.1e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 KXX75638.1 - 8.6e-23 80.8 0.0 8.6e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX75638.1 - 6.5e-14 52.1 0.0 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX75638.1 - 0.001 19.0 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 KR domain ORC6 PF05460.13 KXX75639.1 - 1.1 8.4 4.7 2 7.6 4.7 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Herpes_LMP2 PF07415.11 KXX75639.1 - 9.7 4.8 7.6 15 4.2 7.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Glyco_hydro_114 PF03537.13 KXX75641.1 - 6.8e-45 153.2 0.3 8.3e-45 152.9 0.3 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 HET PF06985.11 KXX75642.1 - 1.1e-18 68.0 0.0 3.5e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HypA PF01155.19 KXX75642.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Glyoxalase PF00903.25 KXX75643.1 - 0.0055 16.9 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HET PF06985.11 KXX75644.1 - 0.002 18.5 0.1 0.0029 17.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MCU PF04678.13 KXX75645.1 - 8.3e-23 81.4 0.1 8.3e-23 81.4 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial calcium uniporter PI3K_1B_p101 PF10486.9 KXX75645.1 - 0.2 9.4 3.4 0.27 8.9 3.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Acetyltransf_8 PF13523.6 KXX75646.1 - 8.1e-44 148.8 0.1 1.2e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DSPc PF00782.20 KXX75647.1 - 1.2e-15 57.5 0.0 7.6e-09 35.5 0.2 3.1 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXX75647.1 - 0.035 14.4 0.0 0.078 13.3 0.0 1.6 2 0 0 2 2 2 0 Rit1 DUSP-like domain Vfa1 PF08432.10 KXX75648.1 - 4.8e-58 196.5 18.7 5.4e-58 196.3 18.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 MTBP_N PF14918.6 KXX75648.1 - 0.051 13.0 6.4 0.18 11.2 6.4 1.8 1 1 0 1 1 1 0 MDM2-binding RR_TM4-6 PF06459.12 KXX75648.1 - 0.068 13.0 12.4 0.086 12.7 12.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCM_bind PF09739.9 KXX75648.1 - 0.083 11.3 7.3 0.096 11.1 7.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 KXX75648.1 - 0.5 9.1 12.5 0.57 8.9 12.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF908 PF06012.12 KXX75648.1 - 0.51 9.7 6.6 0.57 9.5 6.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ATP11 PF06644.11 KXX75648.1 - 2 8.1 15.3 2.6 7.8 15.3 1.1 1 0 0 1 1 1 0 ATP11 protein Sporozoite_P67 PF05642.11 KXX75648.1 - 4 5.4 13.1 4.9 5.1 13.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 KXX75648.1 - 5.1 5.5 12.2 5.4 5.4 12.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPL5 PF18168.1 KXX75648.1 - 5.3 6.2 12.2 6.6 5.9 12.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Ureide_permease PF07168.11 KXX75648.1 - 6.6 5.4 5.3 8.1 5.1 5.3 1.1 1 0 0 1 1 1 0 Ureide permease MAP7 PF05672.11 KXX75648.1 - 6.8 6.3 32.5 9.9 5.8 32.5 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF702 PF05142.12 KXX75648.1 - 8.3 6.9 10.2 7.4 7.0 8.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF702) Rtt106 PF08512.12 KXX75649.1 - 5e-31 107.0 0.0 2.3e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KXX75649.1 - 0.015 15.3 0.0 0.076 13.0 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain SLM4 PF16818.5 KXX75650.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein SLM4 zf-C2H2 PF00096.26 KXX75650.1 - 0.97 10.0 25.3 0.33 11.5 2.5 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX75650.1 - 3.3 8.8 25.2 0.7 10.9 3.2 5.2 4 0 0 4 4 4 0 C2H2-type zinc finger Alpha_L_fucos PF01120.17 KXX75651.1 - 8.5e-28 97.8 0.1 1.2e-27 97.3 0.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 KXX75651.1 - 3.9e-10 39.9 0.7 2.4e-09 37.4 0.0 2.5 2 1 0 2 2 2 1 F5/8 type C domain CVNH PF08881.10 KXX75652.1 - 1.5e-27 96.3 0.0 1.6e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 CVNH domain Methyltransf_23 PF13489.6 KXX75653.1 - 7.5e-24 84.4 0.0 1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX75653.1 - 1.9e-10 41.3 0.0 4.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX75653.1 - 1.1e-07 31.8 0.0 1.3e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX75653.1 - 1.3e-07 32.2 0.0 2.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX75653.1 - 2e-06 28.4 0.0 1.2e-05 26.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX75653.1 - 0.00079 18.8 0.0 0.015 14.6 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXX75653.1 - 0.0013 18.6 0.1 0.033 13.9 0.1 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXX75653.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXX75653.1 - 0.029 14.5 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.15 KXX75653.1 - 0.048 13.0 0.0 0.81 9.0 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Sugar_tr PF00083.24 KXX75654.1 - 3.9e-59 200.7 31.3 1.7e-55 188.7 26.9 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXX75654.1 - 5.4e-10 38.7 27.5 9.9e-10 37.9 27.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily GDPD PF03009.17 KXX75655.1 - 1.4e-21 77.4 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SET PF00856.28 KXX75656.1 - 5.5e-07 30.1 0.0 1.1e-06 29.2 0.0 1.6 1 1 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.10 KXX75657.1 - 3e-37 127.6 0.0 5.9e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KXX75657.1 - 2e-16 60.1 0.0 6.3e-16 58.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX75657.1 - 1.5e-05 24.6 0.1 0.00045 19.8 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXX75657.1 - 0.0013 18.6 0.6 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KXX75657.1 - 0.023 15.2 0.0 0.35 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 KXX75657.1 - 0.028 14.5 1.5 0.14 12.2 0.3 2.5 3 0 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 KXX75657.1 - 0.044 13.3 0.8 0.96 9.0 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KXX75657.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AIG1 PF04548.16 KXX75657.1 - 0.11 11.8 0.0 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Fungal_trans PF04082.18 KXX75659.1 - 3.7e-32 111.4 0.2 7.5e-32 110.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX75659.1 - 1.3e-08 34.8 14.6 2.4e-08 34.0 14.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KXX75659.1 - 0.075 13.1 0.3 0.27 11.4 0.3 2.0 1 0 0 1 1 1 0 bZIP transcription factor DUF4635 PF15466.6 KXX75659.1 - 0.21 11.1 3.4 2.8 7.5 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) SOG2 PF10428.9 KXX75659.1 - 0.31 10.2 12.3 0.51 9.5 12.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein PRP38_assoc PF12871.7 KXX75659.1 - 8.5 7.1 6.3 0.63 10.7 1.1 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PIG-F PF06699.11 KXX75660.1 - 6.2e-67 225.2 4.2 7.6e-67 224.9 4.2 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Translin PF01997.16 KXX75661.1 - 3.2e-46 157.9 0.0 3.7e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF4686 PF15742.5 KXX75661.1 - 0.05 12.7 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Pmp3 PF01679.17 KXX75662.1 - 5e-24 84.3 6.7 5.6e-24 84.1 6.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CN_hydrolase PF00795.22 KXX75663.1 - 3.8e-40 137.9 0.0 5.4e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KXX75663.1 - 8.1e-11 41.5 0.0 2.9e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 NAD synthase NACHT PF05729.12 KXX75664.1 - 1.2e-05 25.3 0.1 9.9e-05 22.3 0.1 2.4 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXX75664.1 - 0.00011 22.4 0.0 0.00046 20.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXX75664.1 - 0.00041 20.3 0.0 0.00094 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KXX75664.1 - 0.0014 19.0 0.0 0.0059 17.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXX75664.1 - 0.0057 17.2 0.0 0.04 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXX75664.1 - 0.0089 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 KXX75664.1 - 0.0091 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KXX75664.1 - 0.011 16.3 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KXX75664.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KXX75664.1 - 0.02 14.1 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KXX75664.1 - 0.03 14.0 0.1 0.09 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KXX75664.1 - 0.034 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 KXX75664.1 - 0.043 14.0 1.2 0.091 12.9 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KXX75664.1 - 0.045 13.5 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXX75664.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 KXX75664.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2075 PF09848.9 KXX75664.1 - 0.19 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 KXX75664.1 - 0.23 10.4 0.0 0.52 9.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PIG-F PF06699.11 KXX75665.1 - 6.2e-67 225.2 4.2 7.6e-67 224.9 4.2 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Translin PF01997.16 KXX75666.1 - 3.2e-46 157.9 0.0 3.7e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF4686 PF15742.5 KXX75666.1 - 0.05 12.7 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Ribosomal_L22e PF01776.17 KXX75667.1 - 5.7e-44 149.0 0.8 6.8e-44 148.7 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mito_carr PF00153.27 KXX75668.1 - 1.7e-52 175.3 0.4 7.4e-18 64.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CAP_N PF01213.19 KXX75668.1 - 0.75 9.2 2.2 1.1 8.6 2.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MARVEL PF01284.23 KXX75670.1 - 3.1e-07 30.5 9.7 9.6e-07 28.9 9.9 1.7 1 1 0 1 1 1 1 Membrane-associating domain adh_short_C2 PF13561.6 KXX75671.1 - 6.9e-53 179.6 0.8 9.4e-53 179.2 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX75671.1 - 7.5e-45 152.8 2.6 9.5e-45 152.5 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX75671.1 - 1.2e-11 44.9 0.7 1.5e-11 44.5 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX75671.1 - 0.0034 16.9 0.2 1.4 8.3 0.1 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family CABS1 PF15367.6 KXX75671.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 AdoHcyase_NAD PF00670.21 KXX75671.1 - 0.066 13.3 0.8 0.16 12.1 0.3 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4470 PF14737.6 KXX75673.1 - 3.1e-22 78.6 0.0 7.3e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KXX75673.1 - 3.9e-11 42.8 11.7 8.4e-11 41.8 11.7 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXX75673.1 - 0.67 10.3 7.9 1.6 9.1 7.9 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding WSC PF01822.19 KXX75674.1 - 1.3e-12 47.7 9.8 2.3e-12 46.9 9.8 1.4 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 KXX75674.1 - 0.00015 21.1 4.3 0.00028 20.2 4.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3042 PF11240.8 KXX75674.1 - 0.0065 16.5 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3042) Insulin_TMD PF17870.1 KXX75674.1 - 0.05 13.7 0.1 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment HET PF06985.11 KXX75675.1 - 2.1e-26 93.0 0.0 3.6e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ACC_epsilon PF13822.6 KXX75675.1 - 4.4 8.1 8.2 8.6 7.1 3.5 2.4 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit zf-C2H2 PF00096.26 KXX75676.1 - 2.9e-08 33.7 19.9 0.0002 21.6 5.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX75676.1 - 2.4e-07 30.9 10.9 0.0037 17.6 2.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX75676.1 - 0.00049 20.7 18.5 0.1 13.5 4.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXX75676.1 - 0.0029 17.3 6.7 0.029 14.1 1.3 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KXX75676.1 - 2.9 8.0 10.1 11 6.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 KXX75676.1 - 8.6 6.7 8.3 17 5.7 8.3 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain DUF3767 PF12597.8 KXX75678.1 - 3.2e-34 116.8 0.2 3.2e-34 116.8 0.2 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3767) SARAF PF06682.12 KXX75678.1 - 0.00056 19.7 4.4 0.00089 19.0 4.4 1.3 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF5523 PF17661.1 KXX75678.1 - 0.033 13.9 10.6 0.88 9.2 0.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Coilin_N PF15862.5 KXX75678.1 - 0.18 11.6 6.7 7.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Coilin N-terminus DUF3464 PF11947.8 KXX75678.1 - 0.59 9.9 9.1 0.41 10.4 0.1 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Syntaxin-18_N PF10496.9 KXX75678.1 - 1.1 9.6 6.6 0.56 10.5 0.3 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus RPA43_OB PF17875.1 KXX75678.1 - 2 9.1 8.6 8.1 7.1 3.1 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I CPSF100_C PF13299.6 KXX75678.1 - 2.4 8.3 10.5 2.7 8.1 1.5 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TMEM214 PF10151.9 KXX75678.1 - 3.2 6.1 12.8 0.019 13.5 3.2 1.7 2 0 0 2 2 2 0 TMEM214, C-terminal, caspase 4 activator DUF719 PF05334.13 KXX75678.1 - 4.1 7.6 9.5 3.7 7.7 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF1744 PF08490.12 KXX75679.1 - 1.3e-158 527.8 0.0 1.8e-158 527.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KXX75679.1 - 5.4e-80 269.1 0.2 8.5e-80 268.4 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KXX75679.1 - 1.4e-14 53.7 0.0 7.4e-12 44.7 0.1 3.4 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KXX75679.1 - 5.2e-09 36.1 0.2 1.3e-08 34.8 0.2 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KXX75679.1 - 1.2e-05 25.4 0.0 3.7e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily DUF4636 PF15468.6 KXX75679.1 - 0.049 13.3 0.9 0.11 12.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DNA_pol3_alpha PF07733.12 KXX75679.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain Sporozoite_P67 PF05642.11 KXX75681.1 - 1.7 6.6 6.9 2.1 6.3 6.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UBA2_C PF16195.5 KXX75682.1 - 0.03 15.0 0.6 0.1 13.3 0.6 1.9 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus ECH_1 PF00378.20 KXX75684.1 - 3.6e-40 137.9 0.1 6e-36 124.0 0.0 3.1 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX75684.1 - 2e-26 93.3 0.1 6.3e-23 81.8 0.0 2.4 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_trans_4_4 PF13579.6 KXX75684.1 - 0.017 15.5 0.9 0.12 12.8 0.3 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain T6PP_N PF18572.1 KXX75685.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Tyrosinase PF00264.20 KXX75686.1 - 1.9e-22 80.7 0.0 2.1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Cellulase PF00150.18 KXX75689.1 - 3.7e-21 75.8 1.3 8.5e-21 74.6 1.3 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KXX75689.1 - 0.0023 17.8 2.4 0.0047 16.9 2.4 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain FadR_C PF07840.12 KXX75689.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 FadR C-terminal domain DUF4360 PF14273.6 KXX75691.1 - 1.5e-27 96.6 1.5 1.9e-27 96.3 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Alpha-amylase PF00128.24 KXX75692.1 - 6.4e-18 65.4 0.0 4e-17 62.8 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Iso_dh PF00180.20 KXX75693.1 - 6.7e-79 265.6 0.0 7.8e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Thioredoxin_7 PF13899.6 KXX75695.1 - 1.1e-16 60.7 0.1 2.4e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 KXX75695.1 - 9.2e-08 32.2 0.0 3.2e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 KXX75695.1 - 2.1e-07 30.6 0.2 4.8e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.15 KXX75695.1 - 0.017 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KXX75695.1 - 0.082 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.25 KXX75696.1 - 4e-69 232.9 0.0 6.5e-69 232.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75696.1 - 9.9e-51 172.5 0.0 1.7e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX75696.1 - 0.00049 19.0 0.0 0.00096 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXX75696.1 - 0.011 15.0 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Lant_dehydr_N PF04738.13 KXX75697.1 - 0.069 11.2 0.1 0.091 10.8 0.1 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Ecm29 PF13001.7 KXX75698.1 - 1.8e-150 501.9 0.0 1.3e-148 495.7 0.0 2.9 2 1 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.22 KXX75698.1 - 0.00067 19.7 2.4 0.84 10.1 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat IFRD PF05004.13 KXX75698.1 - 0.0021 17.3 5.7 0.17 10.9 0.1 3.6 2 1 1 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 KXX75698.1 - 0.0079 16.7 1.6 19 5.9 0.0 5.8 5 0 0 5 5 5 1 HEAT-like repeat RRM_1 PF00076.22 KXX75699.1 - 2e-45 152.5 0.0 1.3e-16 60.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXX75699.1 - 4.4e-05 23.5 0.0 0.0017 18.4 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 KXX75699.1 - 5.1e-05 23.2 0.0 0.0022 18.0 0.1 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KXX75699.1 - 0.00025 21.1 0.1 0.051 13.7 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 KXX75699.1 - 0.0029 17.4 0.0 0.049 13.5 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KXX75699.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C48 PF02902.19 KXX75700.1 - 1.8e-30 106.4 0.0 3e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 KXX75701.1 - 1e-18 67.3 3.6 1.8e-05 25.4 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KXX75701.1 - 0.035 12.8 0.0 0.14 10.8 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ParBc PF02195.18 KXX75701.1 - 0.094 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 ParB-like nuclease domain Ndufs5 PF10200.9 KXX75702.1 - 0.00062 20.0 0.0 0.0008 19.6 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 KXX75702.1 - 0.0032 17.7 0.2 0.0051 17.0 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF3128 PF11326.8 KXX75702.1 - 0.01 16.2 2.7 0.045 14.1 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) CHCH PF06747.13 KXX75702.1 - 0.015 15.4 0.1 0.032 14.4 0.1 1.6 1 1 0 1 1 1 0 CHCH domain Pkinase PF00069.25 KXX75703.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75703.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXX75703.1 - 0.0089 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXX75703.1 - 0.041 13.5 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase NAD_binding_6 PF08030.12 KXX75704.1 - 4.1e-05 23.8 0.0 0.095 12.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KXX75704.1 - 0.00032 21.3 0.0 0.89 10.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXX75704.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Alk_phosphatase PF00245.20 KXX75706.1 - 2.5e-66 224.4 0.0 3.9e-66 223.7 0.0 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KXX75706.1 - 0.00011 21.9 0.8 0.00025 20.8 0.8 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXX75706.1 - 0.00012 21.6 0.1 0.00021 20.8 0.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KXX75706.1 - 0.019 13.6 0.2 0.027 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TPR_2 PF07719.17 KXX75707.1 - 1.1e-25 87.6 18.5 0.00032 20.6 0.1 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX75707.1 - 3e-23 81.9 18.1 8e-21 74.1 1.4 5.5 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KXX75707.1 - 8.5e-23 79.2 12.3 5.7e-05 22.8 2.1 9.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXX75707.1 - 6.4e-22 77.8 18.9 0.0024 18.3 0.3 8.3 6 2 2 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 KXX75707.1 - 3.1e-17 61.3 4.2 0.0021 18.1 0.7 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX75707.1 - 1.5e-16 59.6 25.8 0.0072 17.1 0.1 9.7 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXX75707.1 - 4.4e-15 55.7 23.6 1.2e-06 28.8 0.8 8.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXX75707.1 - 1.3e-14 54.6 27.6 4.2e-05 24.1 1.2 8.8 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXX75707.1 - 2.5e-10 39.8 3.4 0.062 13.0 0.0 6.3 5 1 2 7 7 7 3 TPR repeat TPR_10 PF13374.6 KXX75707.1 - 3.5e-09 36.2 16.7 0.0034 17.2 0.1 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX75707.1 - 8.3e-06 25.5 16.7 2.9 8.1 0.2 8.7 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXX75707.1 - 9.3e-05 22.8 17.2 0.1 13.3 1.1 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXX75707.1 - 0.00034 19.9 7.4 0.52 9.5 0.1 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat Cohesin_load PF10345.9 KXX75707.1 - 0.00081 18.0 0.1 0.38 9.1 0.0 3.0 2 1 0 3 3 3 1 Cohesin loading factor TPR_9 PF13371.6 KXX75707.1 - 0.0022 18.1 10.9 1.7 8.8 0.4 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXX75707.1 - 0.015 14.9 0.0 0.38 10.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 KXX75707.1 - 0.02 14.3 0.3 75 2.6 0.0 4.5 4 1 1 5 5 5 0 Coatomer epsilon subunit TPR_MalT PF17874.1 KXX75707.1 - 0.027 13.9 6.1 0.058 12.8 0.6 3.8 3 1 1 4 4 4 0 MalT-like TPR region TPR_21 PF09976.9 KXX75707.1 - 0.13 12.0 7.2 0.53 10.0 0.1 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat-like domain ORC2 PF04084.14 KXX75708.1 - 7.5e-105 350.5 0.0 6.6e-66 222.5 0.0 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 2 Hydin_ADK PF17213.3 KXX75708.1 - 0.014 15.7 1.9 0.015 15.6 0.4 1.8 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain GMC_oxred_N PF00732.19 KXX75709.1 - 2.5e-54 184.7 0.0 3.9e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX75709.1 - 1e-30 107.2 0.4 2.2e-30 106.1 0.4 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX75709.1 - 0.00041 19.6 0.0 0.14 11.2 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 KXX75709.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXX75709.1 - 0.01 15.4 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX75709.1 - 0.014 15.6 0.1 0.052 13.8 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXX75709.1 - 0.021 13.5 0.0 0.94 8.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 KXX75709.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX75709.1 - 0.056 14.0 0.4 21 5.8 0.1 2.9 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PGP_phosphatase PF09419.10 KXX75710.1 - 3.2e-68 228.6 0.0 3.7e-68 228.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KXX75710.1 - 5.1e-05 23.2 0.0 8.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like AMP-binding PF00501.28 KXX75711.1 - 3.7e-44 151.0 0.0 5.1e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXX75711.1 - 3e-05 23.8 0.8 4.7e-05 23.2 0.1 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus TPR_10 PF13374.6 KXX75712.1 - 5.3e-52 172.4 16.3 8.8e-13 47.7 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXX75712.1 - 1.3e-41 140.8 14.8 1e-17 64.2 2.1 4.9 2 1 2 4 4 4 4 Tetratricopeptide repeat Patatin PF01734.22 KXX75712.1 - 4.4e-23 82.5 0.1 9.2e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_8 PF13181.6 KXX75712.1 - 8.5e-18 63.0 10.9 0.00081 19.4 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXX75712.1 - 1.3e-17 62.4 15.1 0.00015 21.6 0.1 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX75712.1 - 1.9e-15 55.9 17.0 7.5e-05 22.4 0.4 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX75712.1 - 4e-15 56.0 7.9 3.2e-07 30.1 0.9 3.4 1 1 1 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 KXX75712.1 - 3.2e-14 51.8 15.4 0.00045 20.1 0.3 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXX75712.1 - 3.3e-07 30.2 7.6 0.56 10.7 0.1 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX75712.1 - 3.4e-06 27.6 21.7 0.073 13.7 0.3 6.3 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXX75712.1 - 4.2e-06 27.1 16.2 0.14 13.0 0.0 6.4 8 0 0 8 8 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXX75712.1 - 1.8e-05 25.1 7.6 0.027 15.0 2.0 3.6 3 1 0 3 3 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 KXX75712.1 - 0.00011 21.4 0.0 0.00066 18.9 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXX75712.1 - 0.0002 21.8 0.3 0.00074 19.9 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain TPR_21 PF09976.9 KXX75712.1 - 0.0014 18.4 10.1 0.89 9.2 0.3 4.3 2 1 3 5 5 4 2 Tetratricopeptide repeat-like domain ATPase_2 PF01637.18 KXX75712.1 - 0.0017 18.3 0.0 0.0043 17.0 0.0 1.7 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea RPN6_N PF18055.1 KXX75712.1 - 0.01 16.2 0.9 5.7 7.3 0.1 3.8 2 1 3 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain SPO22 PF08631.10 KXX75712.1 - 0.098 12.1 0.3 12 5.3 0.0 3.2 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 KXX75712.1 - 0.1 12.9 0.7 3.3 8.0 0.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Peripla_BP_2 PF01497.18 KXX75712.1 - 0.14 11.7 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein TPR_9 PF13371.6 KXX75712.1 - 0.69 10.1 7.0 17 5.6 0.4 4.1 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXX75712.1 - 1.7 8.4 17.2 0.84 9.4 0.4 4.7 5 0 0 5 5 5 0 TPR repeat TPR_4 PF07721.14 KXX75712.1 - 2.9 8.8 17.3 11 7.0 0.1 5.8 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF1897 PF09005.10 KXX75712.1 - 3.7 7.1 16.5 0.81 9.2 0.5 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) RPN6_C_helix PF18503.1 KXX75712.1 - 7.9 6.3 6.6 43 4.0 0.1 4.2 4 0 0 4 4 4 0 26S proteasome subunit RPN6 C-terminal helix domain Proteasome PF00227.26 KXX75713.1 - 5.9e-37 127.0 0.0 7.4e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.29 KXX75714.1 - 3.6e-49 166.9 0.0 1.2e-48 165.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX75714.1 - 2.6e-33 114.7 0.0 6.6e-33 113.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX75714.1 - 0.0086 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXX75714.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KXX75714.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CutC PF03932.14 KXX75715.1 - 2.4e-14 53.3 0.5 4.9e-05 22.9 0.1 3.9 3 1 0 3 3 3 3 CutC family Myb_DNA-bind_3 PF12776.7 KXX75716.1 - 0.0048 17.8 0.5 0.01 16.8 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1180 PF06679.12 KXX75716.1 - 1.3 9.4 4.2 1.9 8.9 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DJ-1_PfpI PF01965.24 KXX75717.1 - 4.9e-10 39.5 0.0 7.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Pkinase PF00069.25 KXX75719.1 - 1.7e-11 44.0 0.0 9.5e-11 41.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75719.1 - 7.4e-05 22.2 0.0 0.053 12.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXX75719.1 - 0.018 14.1 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AA_permease_2 PF13520.6 KXX75720.1 - 1.7e-74 251.2 33.6 1.7e-74 251.2 33.6 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX75720.1 - 2.6e-16 59.3 26.6 3.6e-16 58.8 26.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2619 PF10942.8 KXX75720.1 - 0.08 13.0 0.3 0.08 13.0 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2619) Spore_permease PF03845.13 KXX75720.1 - 0.18 10.6 3.4 6.9 5.4 2.4 2.5 2 0 0 2 2 2 0 Spore germination protein HET PF06985.11 KXX75721.1 - 6.2e-32 111.0 0.1 1.1e-31 110.2 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VSP PF03302.13 KXX75723.1 - 0.00047 19.1 0.7 0.00068 18.6 0.7 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Asp PF00026.23 KXX75723.1 - 0.0074 15.7 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Podoplanin PF05808.11 KXX75723.1 - 0.016 15.3 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 KXX75723.1 - 0.052 13.0 3.2 0.1 12.0 3.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 KXX75723.1 - 0.2 10.4 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 KXX75723.1 - 1.8 8.5 2.9 3.4 7.7 2.9 1.4 1 0 0 1 1 1 0 Syndecan domain CorA PF01544.18 KXX75724.1 - 0.00017 21.0 2.0 0.00036 20.0 2.0 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF898 PF05987.13 KXX75724.1 - 0.038 13.0 0.3 0.038 13.0 0.3 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF2569 PF10754.9 KXX75724.1 - 0.048 14.1 1.1 0.09 13.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Cellulase PF00150.18 KXX75725.1 - 8.1e-39 133.7 0.1 2.4e-36 125.7 0.2 2.0 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) RNase_H PF00075.24 KXX75727.1 - 9.2e-19 68.0 0.1 2.1e-17 63.7 0.1 2.8 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXX75727.1 - 0.003 17.3 0.0 0.056 13.2 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase-like Glyco_hydro_42M PF08532.10 KXX75727.1 - 0.097 12.2 0.3 0.29 10.6 0.2 1.8 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain HET PF06985.11 KXX75728.1 - 3.7e-13 50.1 0.0 7.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sdh_cyt PF01127.22 KXX75731.1 - 1.1e-17 64.2 1.6 1.5e-17 63.8 1.6 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAF6_C PF07571.13 KXX75732.1 - 8.1e-26 90.2 0.0 1.7e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KXX75732.1 - 2.5e-19 69.2 0.0 6.7e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Complex1_LYR PF05347.15 KXX75734.1 - 0.013 15.5 2.2 0.03 14.4 0.1 2.3 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Mito_carr PF00153.27 KXX75735.1 - 2.2e-39 133.3 7.3 3.8e-14 52.4 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein NPR3 PF03666.13 KXX75735.1 - 0.0098 14.7 0.4 0.013 14.3 0.4 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF1180 PF06679.12 KXX75735.1 - 0.14 12.6 1.7 0.24 11.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Spt20 PF12090.8 KXX75735.1 - 0.56 9.8 6.1 0.82 9.2 6.1 1.2 1 0 0 1 1 1 0 Spt20 family AAA PF00004.29 KXX75736.1 - 2.6e-85 283.5 0.0 2e-46 157.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX75736.1 - 1.3e-17 63.3 0.2 4.9e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KXX75736.1 - 1e-13 51.3 0.0 1.7e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX75736.1 - 1.9e-10 41.4 5.6 0.0015 19.0 0.1 4.4 3 2 2 5 5 4 2 AAA ATPase domain AAA_33 PF13671.6 KXX75736.1 - 2e-09 37.7 0.0 0.0006 20.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXX75736.1 - 2.3e-09 37.4 1.0 0.0004 20.4 0.2 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX75736.1 - 6e-09 36.3 0.9 0.017 15.4 0.0 3.9 3 2 1 4 4 3 2 AAA domain AAA_2 PF07724.14 KXX75736.1 - 1e-08 35.5 0.2 0.00021 21.5 0.0 3.5 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KXX75736.1 - 3.9e-07 30.2 0.0 0.037 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KXX75736.1 - 7.1e-07 29.3 0.0 0.019 14.9 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain TIP49 PF06068.13 KXX75736.1 - 2e-06 27.2 0.0 0.038 13.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain ABC_tran PF00005.27 KXX75736.1 - 2.1e-06 28.3 0.1 0.039 14.5 0.0 2.9 2 1 1 3 3 2 2 ABC transporter RNA_helicase PF00910.22 KXX75736.1 - 2.3e-06 27.9 0.0 0.12 12.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KXX75736.1 - 2.7e-06 28.0 0.0 0.13 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KXX75736.1 - 3.1e-06 27.2 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXX75736.1 - 5.8e-06 26.7 0.5 0.084 13.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KXX75736.1 - 8.7e-06 25.6 0.2 0.092 12.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein DUF815 PF05673.13 KXX75736.1 - 4.9e-05 22.6 0.0 0.028 13.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KXX75736.1 - 5.9e-05 22.5 0.5 0.098 12.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXX75736.1 - 7.1e-05 22.6 0.0 0.38 10.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXX75736.1 - 0.00024 20.5 0.1 0.15 11.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Vps4_C PF09336.10 KXX75736.1 - 0.00025 21.0 0.0 0.026 14.5 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.22 KXX75736.1 - 0.00033 19.9 0.1 0.29 10.3 0.1 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 KXX75736.1 - 0.00038 20.3 0.1 0.87 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KXX75736.1 - 0.00043 20.2 2.2 0.11 12.4 0.2 3.0 3 0 0 3 3 3 1 NACHT domain Cytidylate_kin2 PF13189.6 KXX75736.1 - 0.00052 20.2 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_7 PF12775.7 KXX75736.1 - 0.0007 19.2 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 KXX75736.1 - 0.00081 18.8 0.0 1.8 7.9 0.0 2.7 3 0 0 3 3 2 2 KaiC AAA_25 PF13481.6 KXX75736.1 - 0.0012 18.4 4.9 0.95 9.0 0.3 3.8 3 1 0 4 4 4 1 AAA domain AAA_3 PF07726.11 KXX75736.1 - 0.0021 17.9 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXX75736.1 - 0.0022 17.8 0.3 0.7 9.6 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 KXX75736.1 - 0.0026 17.5 0.4 0.79 9.4 0.1 2.5 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 KXX75736.1 - 0.003 18.0 0.2 1.9 8.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KXX75736.1 - 0.0038 17.2 0.0 3.3 7.5 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KXX75736.1 - 0.004 17.0 0.0 0.84 9.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.6 KXX75736.1 - 0.0052 16.6 2.8 0.67 9.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KXX75736.1 - 0.0068 16.3 0.5 2.5 8.0 0.2 2.7 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 KXX75736.1 - 0.0072 16.0 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 KXX75736.1 - 0.0087 15.8 0.0 0.71 9.6 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 KXX75736.1 - 0.016 15.3 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KXX75736.1 - 0.019 14.4 0.6 3.4 7.1 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 KXX75736.1 - 0.029 14.5 4.9 2.8 8.0 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase AAA_23 PF13476.6 KXX75736.1 - 0.038 14.5 7.7 0.52 10.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain MCM PF00493.23 KXX75736.1 - 0.039 13.0 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain Parvo_NS1 PF01057.17 KXX75736.1 - 0.08 12.0 0.1 5.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KXX75736.1 - 0.092 13.1 0.2 8.7 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXX75736.1 - 0.11 12.2 0.8 14 5.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 KXX75736.1 - 0.11 12.5 0.0 6.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KXX75736.1 - 0.17 11.6 0.0 24 4.6 0.0 3.4 3 1 1 4 4 4 0 DEAD/DEAH box helicase SRPRB PF09439.10 KXX75736.1 - 0.2 11.0 1.6 15 4.9 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CAP_N PF01213.19 KXX75736.1 - 7.7 5.9 7.1 13 5.2 7.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 KXX75737.1 - 1.5e-10 40.9 0.0 3e-05 23.5 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75737.1 - 6.9e-05 22.3 0.0 0.041 13.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase AAA PF00004.29 KXX75738.1 - 2.9e-85 283.4 0.0 2.1e-46 157.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX75738.1 - 1.5e-17 63.1 0.2 5.1e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KXX75738.1 - 1.1e-13 51.2 0.0 1.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX75738.1 - 2.3e-10 41.1 5.7 0.0017 18.8 0.1 4.4 3 2 2 5 5 4 2 AAA ATPase domain AAA_33 PF13671.6 KXX75738.1 - 2.3e-09 37.6 0.0 0.00064 19.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXX75738.1 - 2.3e-09 37.4 0.8 0.00041 20.4 0.2 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX75738.1 - 8.7e-09 35.8 1.3 0.018 15.3 0.0 4.0 3 2 1 4 4 3 2 AAA domain AAA_2 PF07724.14 KXX75738.1 - 1.1e-08 35.4 0.2 0.00022 21.4 0.0 3.6 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KXX75738.1 - 4.3e-07 30.0 0.0 0.039 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KXX75738.1 - 7.7e-07 29.2 0.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain TIP49 PF06068.13 KXX75738.1 - 2.2e-06 27.1 0.0 0.04 13.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain ABC_tran PF00005.27 KXX75738.1 - 2.2e-06 28.2 0.1 0.041 14.4 0.0 2.9 2 1 1 3 3 2 2 ABC transporter RNA_helicase PF00910.22 KXX75738.1 - 2.6e-06 27.8 0.0 0.13 12.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KXX75738.1 - 2.9e-06 27.9 0.0 0.14 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KXX75738.1 - 3.3e-06 27.1 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXX75738.1 - 6.3e-06 26.5 0.5 0.088 13.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KXX75738.1 - 9.6e-06 25.4 0.2 0.096 12.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein DUF815 PF05673.13 KXX75738.1 - 5.5e-05 22.5 0.0 0.03 13.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KXX75738.1 - 6.5e-05 22.4 0.5 0.1 12.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXX75738.1 - 7.8e-05 22.4 0.0 0.4 10.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.10 KXX75738.1 - 0.00025 20.9 0.0 0.027 14.5 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.12 KXX75738.1 - 0.00026 20.3 0.1 0.16 11.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 KXX75738.1 - 0.00036 19.8 0.1 0.31 10.2 0.1 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 KXX75738.1 - 0.00041 20.1 0.1 0.91 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KXX75738.1 - 0.00048 20.1 2.2 0.11 12.4 0.2 3.0 3 0 0 3 3 3 1 NACHT domain Cytidylate_kin2 PF13189.6 KXX75738.1 - 0.00057 20.1 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_7 PF12775.7 KXX75738.1 - 0.00076 19.0 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 KXX75738.1 - 0.00089 18.7 0.0 1.9 7.8 0.0 2.7 3 0 0 3 3 2 2 KaiC AAA_25 PF13481.6 KXX75738.1 - 0.0013 18.4 4.8 0.98 9.0 0.3 3.8 3 1 0 4 4 4 1 AAA domain AAA_3 PF07726.11 KXX75738.1 - 0.0023 17.8 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXX75738.1 - 0.0025 17.6 0.3 0.73 9.5 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 KXX75738.1 - 0.0028 17.4 0.4 0.82 9.4 0.1 2.5 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 KXX75738.1 - 0.0033 17.9 0.2 2 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXX75738.1 - 0.0034 17.2 3.7 0.7 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KXX75738.1 - 0.0041 17.1 0.0 3.4 7.5 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KXX75738.1 - 0.0044 16.9 0.0 0.88 9.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein NTPase_1 PF03266.15 KXX75738.1 - 0.0075 16.2 0.5 2.6 7.9 0.2 2.7 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 KXX75738.1 - 0.0079 15.9 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 KXX75738.1 - 0.0094 15.7 0.0 0.74 9.6 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 KXX75738.1 - 0.017 15.2 0.0 0.84 9.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KXX75738.1 - 0.021 14.3 0.6 3.5 7.0 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 KXX75738.1 - 0.031 14.4 4.9 3 8.0 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase MCM PF00493.23 KXX75738.1 - 0.043 12.9 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain Parvo_NS1 PF01057.17 KXX75738.1 - 0.087 11.9 0.1 5.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 KXX75738.1 - 0.095 13.2 9.6 0.54 10.7 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KXX75738.1 - 0.1 13.0 0.2 9.1 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KXX75738.1 - 0.12 12.3 0.0 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KXX75738.1 - 0.2 11.4 0.0 25 4.6 0.0 3.4 3 1 1 4 4 4 0 DEAD/DEAH box helicase SRPRB PF09439.10 KXX75738.1 - 0.24 10.8 1.7 16 4.9 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CAP_N PF01213.19 KXX75738.1 - 7.5 5.9 7.0 12 5.2 7.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal But2 PF09792.9 KXX75740.1 - 2.2e-05 24.9 0.1 3.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain AAA PF00004.29 KXX75741.1 - 4.1e-20 72.6 0.0 9e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX75741.1 - 0.0011 19.2 0.5 0.041 14.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXX75741.1 - 0.0076 16.3 0.1 0.027 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXX75741.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX75741.1 - 0.067 13.6 0.2 0.067 13.6 0.2 2.7 2 1 1 3 3 3 0 AAA ATPase domain RuvB_N PF05496.12 KXX75741.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXX75741.1 - 0.1 13.2 0.0 0.37 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXX75741.1 - 0.12 12.0 0.0 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 KXX75741.1 - 0.14 11.8 0.1 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Beta-lactamase PF00144.24 KXX75742.1 - 7.2e-45 153.7 0.0 9e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KXX75742.1 - 5.7e-05 22.7 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KXX75742.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family HET PF06985.11 KXX75743.1 - 8.6e-28 97.5 0.0 1.6e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zinc_ribbon_16 PF17034.5 KXX75743.1 - 0.22 11.8 0.0 0.62 10.3 0.0 1.7 2 0 0 2 2 2 0 Zinc-ribbon like family Acetyltransf_3 PF13302.7 KXX75744.1 - 2.1e-08 34.9 0.0 2.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX75744.1 - 5.7e-06 26.6 0.0 8.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ilar_coat PF01787.16 KXX75744.1 - 0.0061 16.4 0.0 0.0081 16.0 0.0 1.1 1 0 0 1 1 1 1 Ilarvirus coat protein DIL PF01843.19 KXX75745.1 - 1e-32 112.5 0.8 2.1e-32 111.5 0.8 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KXX75745.1 - 6.4e-14 52.3 0.0 2.4e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX75745.1 - 3.7e-13 49.7 0.1 1.6e-07 31.7 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX75745.1 - 7.7e-11 42.0 0.1 2.3e-06 27.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXX75745.1 - 2.9e-08 33.8 0.6 0.0082 16.5 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KXX75745.1 - 1.4e-06 28.2 0.1 0.28 11.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat EcKinase PF02958.20 KXX75746.1 - 2.1e-18 66.7 0.1 2.5e-11 43.5 0.4 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 KXX75746.1 - 4.2e-08 33.4 2.0 8.4e-08 32.4 2.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXX75746.1 - 4.6e-08 32.4 0.1 7.4e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Cytochrom_B561 PF03188.16 KXX75747.1 - 7e-17 61.8 6.0 7e-17 61.8 6.0 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXX75747.1 - 0.0092 16.1 12.3 1.7 8.8 0.1 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF4079) DUF588 PF04535.12 KXX75747.1 - 0.013 15.3 0.9 0.021 14.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) SLATT_3 PF18184.1 KXX75747.1 - 0.26 11.4 2.5 9.6 6.3 0.4 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 DUF2162 PF09930.9 KXX75747.1 - 0.33 10.3 8.5 0.11 11.9 3.0 2.2 1 1 1 2 2 2 0 Predicted transporter (DUF2162) Allantoicase PF03561.15 KXX75748.1 - 9.6e-93 307.7 0.1 1.9e-47 160.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Sugar_tr PF00083.24 KXX75749.1 - 1.4e-100 337.3 16.0 1.8e-100 336.9 16.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX75749.1 - 1.4e-28 99.9 15.7 1.4e-28 99.9 15.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXX75749.1 - 6.3e-08 31.6 21.4 6.5e-07 28.3 5.6 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 KXX75749.1 - 0.011 14.6 1.8 0.017 14.0 1.8 1.3 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM Chs7 PF12271.8 KXX75750.1 - 1.7e-109 365.6 0.6 2e-109 365.4 0.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone AMP-binding PF00501.28 KXX75751.1 - 9.3e-72 241.9 0.0 1.1e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX75751.1 - 2.5e-14 54.0 0.1 8.7e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Lipase_GDSL_2 PF13472.6 KXX75752.1 - 1.9e-20 74.0 1.1 2.5e-20 73.6 1.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX75752.1 - 4.3e-10 39.9 0.0 5.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXX75752.1 - 2.4e-05 24.5 0.0 4.7e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family NMT1 PF09084.11 KXX75753.1 - 3.6e-78 262.4 0.0 5.1e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KXX75753.1 - 2.8e-05 23.9 0.0 1 9.0 0.0 3.5 3 1 0 3 3 3 2 NMT1-like family FMN_red PF03358.15 KXX75753.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Abhydrolase_1 PF00561.20 KXX75754.1 - 6.5e-18 65.3 0.0 7.9e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX75754.1 - 4.7e-13 49.0 0.0 9.5e-12 44.7 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXX75754.1 - 9.1e-11 42.8 0.0 1.2e-10 42.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KXX75754.1 - 0.00094 18.8 0.0 0.0018 17.9 0.0 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Myb_DNA-bind_3 PF12776.7 KXX75755.1 - 5.5e-08 33.7 0.4 2.4e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain CDV3 PF15359.6 KXX75755.1 - 0.051 14.1 4.2 5.2 7.6 1.9 2.3 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Sugar_tr PF00083.24 KXX75756.1 - 4e-100 335.8 12.7 4.5e-100 335.6 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX75756.1 - 4e-27 95.1 26.6 4.3e-20 71.9 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.12 KXX75757.1 - 2.9e-30 105.6 0.0 4.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KXX75757.1 - 0.04 13.8 0.7 0.096 12.6 0.7 1.6 1 1 0 1 1 1 0 Glycoside hydrolase family 44 PLA2_B PF01735.18 KXX75758.1 - 1.7e-141 472.0 2.9 2.5e-128 428.6 0.0 2.0 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Clr5 PF14420.6 KXX75760.1 - 4.9e-09 36.3 0.2 9.4e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 Clr5 domain Ppx-GppA PF02541.16 KXX75761.1 - 3e-05 23.6 0.0 5.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF4794 PF16042.5 KXX75762.1 - 2.5 9.1 8.8 15 6.7 8.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4794) DUF5477 PF17571.2 KXX75763.1 - 0.17 12.1 4.0 7.1 6.9 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5477) Glyco_hydro_76 PF03663.14 KXX75764.1 - 6e-117 391.2 4.5 7.1e-117 391.0 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXX75764.1 - 0.33 10.0 7.2 0.22 10.6 0.3 2.9 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 NACHT PF05729.12 KXX75765.1 - 0.067 13.1 0.1 0.15 12.0 0.1 1.6 1 1 0 1 1 1 0 NACHT domain Glyco_hydro_92N PF17678.1 KXX75766.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 N-terminal domain DUF16 PF01519.16 KXX75767.1 - 0.056 13.9 1.1 0.16 12.5 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 KXX75767.1 - 0.11 13.1 6.4 4.1 8.1 2.4 2.7 1 1 1 2 2 2 0 SlyX Herpes_UL6 PF01763.16 KXX75767.1 - 0.11 11.0 0.4 0.16 10.4 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.15 KXX75767.1 - 1.3 8.8 3.4 4.4 7.1 2.8 1.9 1 1 1 2 2 2 0 Septum formation initiator Con-6 PF10346.9 KXX75768.1 - 3.8e-31 106.8 5.0 2.1e-16 59.6 0.7 2.2 2 0 0 2 2 2 2 Conidiation protein 6 Cyclin PF08613.11 KXX75769.1 - 4.8e-42 144.1 0.0 7.4e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXX75769.1 - 0.0043 16.8 0.0 0.0063 16.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain adh_short PF00106.25 KXX75770.1 - 8.5e-27 93.9 0.0 1.4e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX75770.1 - 5.6e-15 55.5 0.0 7.4e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXX75770.1 - 0.00012 21.7 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KXX75770.1 - 0.00012 22.0 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXX75770.1 - 0.00025 20.6 0.1 0.21 11.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXX75770.1 - 0.026 14.4 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding Pkinase PF00069.25 KXX75771.1 - 6.6e-21 74.9 0.0 1.3e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75771.1 - 1.2e-16 60.8 0.0 2.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KXX75771.1 - 4.2e-16 59.3 0.0 0.00073 20.1 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX75771.1 - 1.6e-14 52.5 3.2 0.0059 17.0 0.0 7.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KXX75771.1 - 1e-13 51.2 0.9 0.035 14.4 0.0 6.5 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX75771.1 - 1.3e-10 41.6 0.2 2.6e-05 24.7 0.1 5.6 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Sel1 PF08238.12 KXX75771.1 - 0.0076 16.9 0.2 0.024 15.3 0.2 1.9 1 0 0 1 1 1 1 Sel1 repeat Kdo PF06293.14 KXX75771.1 - 0.015 14.7 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank PF00023.30 KXX75771.1 - 4.7 7.8 14.0 1e+02 3.6 0.1 7.2 9 0 0 9 9 9 0 Ankyrin repeat CHZ PF09649.10 KXX75772.1 - 0.00065 19.1 1.1 0.0011 18.4 1.1 1.3 1 0 0 1 1 1 1 Histone chaperone domain CHZ Peptidase_M24 PF00557.24 KXX75773.1 - 2.3e-55 187.5 0.1 3.3e-55 187.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXX75773.1 - 4.1e-26 91.1 0.0 7.6e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Ribonuclease_3 PF00636.26 KXX75776.1 - 2.2e-27 95.7 0.0 8e-15 55.4 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXX75776.1 - 1.3e-19 70.7 0.1 2.7e-07 30.8 0.0 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.31 KXX75776.1 - 1.7e-18 66.9 0.1 5e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX75776.1 - 3e-15 56.4 0.0 5.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 KXX75776.1 - 9.1e-14 51.4 0.0 4.3e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.15 KXX75776.1 - 1.4e-11 44.7 0.0 2.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helo_like_N PF17111.5 KXX75776.1 - 0.69 9.2 2.4 0.94 8.8 0.1 2.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Glyco_hydro_62 PF03664.13 KXX75777.1 - 3.8e-62 210.1 1.4 4.6e-62 209.8 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_43 PF04616.14 KXX75778.1 - 5.3e-62 209.7 5.4 6.3e-62 209.5 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.13 KXX75778.1 - 2.6e-15 56.6 1.2 2.9e-07 30.6 0.2 3.1 1 1 2 3 3 3 2 Alpha-L-arabinofuranosidase B (ABFB) domain Prok-E2_D PF14460.6 KXX75778.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family D TPP_enzyme_N PF02776.18 KXX75779.1 - 6e-40 136.7 0.1 1.2e-38 132.4 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXX75779.1 - 1.7e-20 73.3 0.0 4e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXX75779.1 - 7.9e-12 45.1 0.0 5.1e-11 42.5 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain DUF1996 PF09362.10 KXX75780.1 - 8.8e-80 268.1 0.1 1.1e-79 267.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA_22 PF13401.6 KXX75781.1 - 0.00029 21.1 0.0 0.00084 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX75781.1 - 0.00035 21.0 0.0 0.0023 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXX75781.1 - 0.0041 17.1 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 KXX75781.1 - 0.0041 17.6 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 KXX75781.1 - 0.021 14.7 0.0 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KXX75781.1 - 0.026 14.6 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KXX75781.1 - 0.028 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KXX75781.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KXX75781.1 - 0.043 14.4 0.0 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXX75781.1 - 0.068 13.6 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KXX75781.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXX75781.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXX75781.1 - 0.22 11.4 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 NTPase SesA PF17107.5 KXX75782.1 - 0.0031 17.7 0.1 0.0039 17.4 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF948 PF06103.11 KXX75782.1 - 0.012 15.8 0.0 0.09 13.1 0.0 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Plasmid_RAQPRD PF09686.10 KXX75782.1 - 0.52 10.6 4.0 0.5 10.6 2.4 1.7 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) AltA1 PF16541.5 KXX75783.1 - 5.2e-06 27.3 0.0 7.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 HeLo PF14479.6 KXX75785.1 - 1.6e-29 103.2 0.3 2.7e-29 102.5 0.3 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF4972 PF16342.5 KXX75785.1 - 0.054 13.2 0.2 0.58 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) DUF1627 PF07789.12 KXX75785.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Fungal_trans_2 PF11951.8 KXX75786.1 - 3.2e-40 138.2 2.7 1.1e-39 136.4 2.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Paf67 PF10255.9 KXX75787.1 - 1.8e-154 514.7 0.1 2.1e-154 514.4 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KXX75787.1 - 0.016 15.2 0.2 0.16 12.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HBS1_N PF08938.10 KXX75787.1 - 0.026 14.8 1.0 0.062 13.6 1.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus GTP_EFTU PF00009.27 KXX75788.1 - 1.1e-55 188.3 0.0 1.8e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXX75788.1 - 4.1e-16 58.8 0.0 9.9e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXX75788.1 - 1.9e-10 40.9 0.0 4.7e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KXX75788.1 - 3.5e-07 30.0 0.0 1.6e-05 24.7 0.0 3.1 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.6 KXX75788.1 - 4.5e-06 26.7 0.0 9.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXX75788.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase RRM_1 PF00076.22 KXX75789.1 - 8.4e-10 38.3 0.0 1.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 KXX75789.1 - 0.28 11.2 10.7 0.43 10.6 10.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hamartin PF04388.12 KXX75789.1 - 4.7 5.7 7.8 5.6 5.5 7.8 1.1 1 0 0 1 1 1 0 Hamartin protein RR_TM4-6 PF06459.12 KXX75789.1 - 5.3 6.8 8.5 8 6.2 8.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KXX75789.1 - 9.9 4.8 5.7 15 4.2 5.7 1.5 1 0 0 1 1 1 0 Presenilin FAD_binding_4 PF01565.23 KXX75792.1 - 6.6e-18 64.8 1.5 1.4e-17 63.8 1.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX75792.1 - 1.2e-10 41.3 0.7 2.2e-10 40.5 0.7 1.5 1 0 0 1 1 1 1 Berberine and berberine like LXG PF04740.12 KXX75793.1 - 0.029 14.1 0.0 0.033 13.9 0.0 1.0 1 0 0 1 1 1 0 LXG domain of WXG superfamily Usp PF00582.26 KXX75794.1 - 2.3e-14 54.1 0.0 7.1e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family DUF1871 PF08958.10 KXX75794.1 - 0.19 12.1 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) Ribosomal_L32e PF01655.18 KXX75795.1 - 4.9e-50 168.5 1.9 4.9e-50 168.5 1.9 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 DnaJ_C PF01556.18 KXX75796.1 - 1.8e-34 119.0 0.1 2.6e-34 118.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXX75796.1 - 1.3e-23 82.9 2.2 2.7e-23 81.8 2.2 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXX75796.1 - 6.3e-13 48.9 17.2 9.8e-13 48.3 17.2 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KXX75796.1 - 0.25 11.4 7.7 3 7.9 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 KXX75796.1 - 1.8 7.8 2.7 13 4.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) TackOD1 PF18551.1 KXX75796.1 - 2.1 8.0 8.3 2.2 7.9 1.7 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Anti-TRAP PF15777.5 KXX75796.1 - 2.4 8.2 16.0 0.52 10.3 3.4 2.9 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 KXX75796.1 - 2.6 8.3 8.3 5.1 7.3 1.4 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 KXX75796.1 - 6 7.0 8.9 5 7.2 1.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon Aminotran_5 PF00266.19 KXX75797.1 - 7.2e-11 41.7 0.0 8.6e-10 38.1 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXX75797.1 - 1.5e-05 24.5 0.3 3e-05 23.5 0.3 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXX75797.1 - 0.00014 20.6 0.0 0.0002 20.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme tRNA-synt_1c PF00749.21 KXX75798.1 - 1.2e-90 303.7 0.0 1.6e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Fmp27 PF10344.9 KXX75799.1 - 3.9e-248 826.0 0.0 5.4e-248 825.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KXX75799.1 - 2.1e-200 666.6 0.1 2.1e-200 666.6 0.1 3.1 3 0 0 3 3 3 2 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KXX75799.1 - 8.8e-185 615.2 0.0 1.6e-184 614.3 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KXX75799.1 - 2.2e-58 196.8 0.0 5e-58 195.6 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KXX75799.1 - 4.4e-54 182.6 0.1 9.4e-54 181.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KXX75799.1 - 4e-32 111.0 0.1 1.7e-31 109.0 0.1 2.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain JAB PF01398.21 KXX75799.1 - 2.2e-26 92.2 0.1 5.1e-26 91.0 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KXX75799.1 - 1e-16 61.6 4.2 4.6e-16 59.5 0.0 3.6 4 0 0 4 4 4 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KXX75799.1 - 0.00077 19.2 0.2 0.0042 16.9 0.0 2.4 3 0 0 3 3 3 1 Prokaryotic homologs of the JAB domain HTH_32 PF13565.6 KXX75799.1 - 1.1 9.9 4.3 32 5.2 0.3 3.6 2 0 0 2 2 2 0 Homeodomain-like domain HET PF06985.11 KXX75800.1 - 1.4e-26 93.6 1.9 8.3e-26 91.1 1.6 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.14 KXX75801.1 - 5.4e-42 144.1 4.0 6.2e-42 143.9 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short PF00106.25 KXX75802.1 - 4.1e-22 78.6 0.1 5.3e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX75802.1 - 3.1e-18 66.2 0.1 5.2e-18 65.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX75802.1 - 1.1e-09 38.4 0.1 1.9e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXX75802.1 - 0.013 14.7 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXX75802.1 - 0.028 13.9 1.6 0.23 10.9 1.6 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ILVD_EDD PF00920.21 KXX75803.1 - 5.2e-153 510.4 0.1 5.9e-153 510.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family HepII_C PF18675.1 KXX75803.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Heparinase II C-terminal domain Hemerythrin PF01814.23 KXX75804.1 - 4.9e-05 24.0 1.7 8.4e-05 23.2 1.1 1.7 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF3014 PF11219.8 KXX75804.1 - 0.027 14.7 0.0 0.049 13.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3014) Glyco_hydro_10 PF00331.20 KXX75805.1 - 1.8e-97 326.3 0.1 2.1e-97 326.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.24 KXX75805.1 - 0.013 15.0 0.0 0.033 13.6 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel WI12 PF07107.11 KXX75805.1 - 0.091 12.9 0.2 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Wound-induced protein WI12 SOSSC PF15925.5 KXX75806.1 - 0.1 13.9 1.1 0.33 12.3 0.1 2.3 2 0 0 2 2 2 0 SOSS complex subunit C Glyco_hydro_43 PF04616.14 KXX75807.1 - 2.4e-36 125.6 0.6 2.9e-36 125.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 KXX75807.1 - 0.055 13.1 0.2 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat Nucleos_tra2_C PF07662.13 KXX75808.1 - 1.2e-68 231.1 0.2 1.2e-68 231.1 0.2 2.4 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KXX75808.1 - 2.4e-20 72.9 3.4 2.4e-20 72.9 3.4 3.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Sugar_tr PF00083.24 KXX75809.1 - 1.9e-106 356.7 17.8 2.2e-106 356.4 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX75809.1 - 1.2e-28 100.1 39.6 5.9e-25 87.9 20.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PNK3P PF08645.11 KXX75810.1 - 3.9e-56 189.2 0.0 5.9e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KXX75810.1 - 6.4e-28 97.7 0.0 2e-14 54.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain APS_kinase PF01583.20 KXX75810.1 - 0.0076 16.2 0.0 0.1 12.5 0.0 2.3 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_29 PF13555.6 KXX75810.1 - 0.032 14.0 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXX75810.1 - 0.09 12.0 0.0 0.7 9.1 0.0 2.2 2 1 1 3 3 3 0 Zeta toxin AAA_23 PF13476.6 KXX75810.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX75810.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain HET PF06985.11 KXX75811.1 - 2.5e-33 115.5 0.0 5.1e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MLTR_LBD PF17765.1 KXX75811.1 - 0.076 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain BBE PF08031.12 KXX75812.1 - 4.7e-08 33.0 0.0 7.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KXX75813.1 - 4.2e-21 75.1 1.0 8.5e-21 74.2 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX75813.1 - 1.7e-12 47.2 0.2 4.4e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXX75813.1 - 0.23 10.8 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GMC_oxred_N PF00732.19 KXX75814.1 - 2.6e-59 201.0 0.0 3.3e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX75814.1 - 1.6e-29 103.2 0.1 3.2e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX75814.1 - 2.5e-08 33.4 0.4 3.8e-07 29.5 0.2 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXX75814.1 - 1.9e-05 24.8 0.0 6.4e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX75814.1 - 7.4e-05 22.0 0.1 0.00011 21.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXX75814.1 - 0.00042 20.0 0.2 0.015 14.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX75814.1 - 0.0039 16.5 0.1 0.0064 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXX75814.1 - 0.039 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KXX75814.1 - 0.048 12.9 0.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX75814.1 - 0.22 10.7 1.3 1.8 7.7 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NTF2 PF02136.20 KXX75815.1 - 2.1e-29 102.5 0.0 2.4e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain EcoRI PF02963.16 KXX75815.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease EcoRI Cg6151-P PF10233.9 KXX75816.1 - 1.7e-43 147.5 18.0 2e-43 147.3 18.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Seipin PF06775.14 KXX75817.1 - 1.4e-51 175.5 0.1 1.8e-51 175.1 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) MAGE_N PF12440.8 KXX75818.1 - 0.0005 20.7 0.6 0.0005 20.7 0.6 3.1 3 0 0 3 3 3 1 Melanoma associated antigen family N terminal Cwf_Cwc_15 PF04889.12 KXX75818.1 - 0.38 10.4 14.1 0.25 11.1 4.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Aim21 PF11489.8 KXX75819.1 - 9.1e-212 705.9 83.3 9.1e-212 705.9 83.3 2.2 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Nup96 PF12110.8 KXX75820.1 - 5.2e-57 193.2 0.3 3.3e-55 187.3 0.3 2.3 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KXX75820.1 - 7.6e-47 159.2 0.0 1.2e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KXX75820.1 - 2.9e-10 40.8 114.6 4.7e-06 27.4 29.6 10.1 3 2 4 7 7 7 4 Nucleoporin FG repeat region p450 PF00067.22 KXX75821.1 - 2.8e-29 102.2 0.0 6.3e-27 94.4 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Gryzun PF07919.12 KXX75822.1 - 8.3e-194 645.7 0.0 1e-180 602.5 0.0 2.0 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KXX75822.1 - 1.1e-90 303.7 2.3 4.2e-86 288.7 3.1 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KXX75822.1 - 0.0027 17.6 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Ran-binding PF05508.11 KXX75823.1 - 2e-117 391.6 0.0 2.6e-117 391.3 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein SDA1 PF05285.12 KXX75823.1 - 1.2 8.4 5.2 1.7 8.0 5.2 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KXX75823.1 - 6.5 4.7 5.4 9.5 4.2 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Dna2 PF08696.11 KXX75824.1 - 1.3e-71 240.6 0.1 3e-71 239.4 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 KXX75824.1 - 5.4e-52 176.3 0.0 1.1e-51 175.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXX75824.1 - 1.9e-31 109.8 0.7 2.2e-16 60.5 0.0 2.6 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KXX75824.1 - 1.4e-14 54.3 0.0 6.5e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXX75824.1 - 1.7e-11 44.6 0.1 7.6e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Cas_Cas4 PF01930.17 KXX75824.1 - 4.3e-09 36.7 0.3 4.6e-08 33.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 Abhydrolase_6 PF12697.7 KXX75824.1 - 9.4e-07 29.6 0.6 9.4e-07 29.6 0.6 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Viral_helicase1 PF01443.18 KXX75824.1 - 0.00015 21.6 0.1 0.77 9.5 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXX75824.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KXX75824.1 - 0.0031 17.4 0.0 0.0099 15.7 0.0 1.8 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 KXX75824.1 - 0.006 17.0 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PEPCK_ATP PF01293.20 KXX75824.1 - 0.013 14.2 0.1 0.021 13.5 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_7 PF12775.7 KXX75824.1 - 0.015 14.8 0.1 0.038 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 KXX75824.1 - 0.023 14.4 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 KXX75824.1 - 0.032 13.9 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KXX75824.1 - 0.055 13.0 0.2 1 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 KXX75824.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 KXX75824.1 - 0.16 11.1 0.1 0.93 8.6 0.1 2.0 1 1 0 1 1 1 0 PIF1-like helicase adh_short_C2 PF13561.6 KXX75825.1 - 1.5e-30 106.5 2.1 8e-29 100.9 2.1 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX75825.1 - 2.5e-28 98.9 0.4 8.7e-28 97.1 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX75825.1 - 9e-05 22.4 0.1 9e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 KR domain GTP_EFTU PF00009.27 KXX75826.1 - 4.6e-42 143.8 0.1 7.7e-42 143.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXX75826.1 - 2.9e-22 79.1 0.0 1e-21 77.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXX75826.1 - 2.2e-07 31.1 0.2 5.7e-07 29.8 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXX75826.1 - 0.0006 19.9 0.0 0.0047 17.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase TonB_N PF16031.5 KXX75826.1 - 0.57 10.7 16.8 1 9.9 16.8 1.4 1 0 0 1 1 1 0 TonB polyproline region CENP-N PF05238.13 KXX75826.1 - 2.7 7.2 6.1 4.2 6.6 6.1 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Mitofilin PF09731.9 KXX75826.1 - 8.2 5.1 16.1 12 4.5 16.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein UCH_1 PF13423.6 KXX75827.1 - 2.5e-102 342.7 0.0 4.9e-102 341.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KXX75827.1 - 6.5e-23 82.1 0.0 1.1e-22 81.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KXX75827.1 - 2.2e-07 30.6 0.0 5.8e-05 22.7 0.0 2.6 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.27 KXX75828.1 - 9.1e-53 176.2 5.1 1.3e-18 66.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_17 PF00332.18 KXX75829.1 - 9.7e-09 35.2 0.7 3.4e-06 26.9 0.3 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF4834 PF16118.5 KXX75829.1 - 3.2 8.8 0.0 3.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) TPR_12 PF13424.6 KXX75831.1 - 1.2e-10 41.6 15.1 0.00053 20.2 1.0 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX75831.1 - 6.9e-08 32.0 10.6 0.25 11.6 0.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX75831.1 - 1.3e-05 24.8 4.6 11 6.0 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX75831.1 - 0.0013 18.8 5.4 5.6 7.4 0.1 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat Ank_4 PF13637.6 KXX75831.1 - 0.0022 18.5 0.0 0.008 16.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HET PF06985.11 KXX75831.1 - 0.0033 17.8 0.8 0.015 15.6 0.0 2.4 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KXX75831.1 - 0.0042 17.6 0.1 0.024 15.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) TPR_7 PF13176.6 KXX75831.1 - 0.037 14.0 3.8 2.4 8.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXX75831.1 - 0.098 13.3 6.8 6.2 7.6 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXX75831.1 - 0.7 10.7 11.4 6.1 7.8 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX75831.1 - 1.6 9.5 13.1 8 7.3 0.5 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX75831.1 - 8.4 7.5 17.3 13 6.9 0.1 5.9 8 0 0 8 8 5 0 Tetratricopeptide repeat Glyco_hydro_61 PF03443.14 KXX75832.1 - 6.1e-21 75.3 0.0 1.3e-20 74.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXX75832.1 - 1.8e-11 43.8 15.9 5e-11 42.4 15.9 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Ank_2 PF12796.7 KXX75833.1 - 2.6e-10 40.7 0.2 4.8e-10 39.9 0.2 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX75833.1 - 4.1e-08 33.6 0.0 0.01 16.4 0.0 2.9 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX75833.1 - 2.6e-07 30.8 0.0 3.3e-05 24.1 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75833.1 - 2e-05 24.6 0.0 0.052 14.1 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXX75833.1 - 0.013 15.9 0.1 1.4 9.5 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat HEAT_2 PF13646.6 KXX75833.1 - 0.074 13.5 0.2 0.51 10.8 0.6 2.1 2 1 0 2 2 2 0 HEAT repeats FAD_binding_3 PF01494.19 KXX75834.1 - 4.4e-17 62.4 0.1 7.5e-16 58.3 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX75834.1 - 2.7e-07 30.1 0.1 0.00012 21.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX75834.1 - 1e-05 24.8 0.4 1.6e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KXX75834.1 - 1.7e-05 23.9 0.0 0.0088 14.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KXX75834.1 - 6.9e-05 23.0 0.6 0.00031 20.9 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXX75834.1 - 0.00018 20.8 0.4 0.00023 20.4 0.4 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXX75834.1 - 0.00033 19.5 0.0 0.12 11.1 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KXX75834.1 - 0.0007 19.3 2.5 0.016 14.8 1.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX75834.1 - 0.0022 18.5 0.0 0.021 15.4 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXX75834.1 - 0.0057 16.0 0.4 0.033 13.5 0.8 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase MREG PF15812.5 KXX75834.1 - 0.017 15.4 0.1 0.032 14.5 0.1 1.4 1 0 0 1 1 1 0 Melanoregulin Pyr_redox_3 PF13738.6 KXX75834.1 - 0.022 14.0 0.0 0.094 12.0 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3907 PF13047.6 KXX75834.1 - 0.072 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) TEX29 PF15839.5 KXX75834.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 29 protein ThiF PF00899.21 KXX75834.1 - 0.19 11.0 0.8 2.5 7.4 0.2 2.2 2 0 0 2 2 2 0 ThiF family FAD_binding_4 PF01565.23 KXX75835.1 - 1.5e-28 99.3 0.0 2.5e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXX75835.1 - 2.4e-09 37.2 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain zf-C2H2_jaz PF12171.8 KXX75836.1 - 0.0088 16.3 8.3 0.87 10.0 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXX75836.1 - 0.015 15.8 0.5 0.015 15.8 0.5 5.0 4 1 1 5 5 5 0 Zinc finger, C2H2 type MGAT2 PF05060.14 KXX75836.1 - 0.027 13.5 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) zf-met PF12874.7 KXX75836.1 - 0.034 14.6 0.8 5.2 7.6 0.1 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXX75836.1 - 0.19 11.8 1.1 0.68 10.0 1.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Zn_clus PF00172.18 KXX75836.1 - 0.62 10.2 17.8 0.32 11.2 10.6 2.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KXX75836.1 - 1.3 9.6 12.4 0.071 13.6 4.3 3.0 3 0 0 3 3 3 0 Zinc-finger double domain B12D PF06522.11 KXX75837.1 - 0.058 13.2 10.2 0.095 12.5 0.4 2.9 2 1 1 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit p450 PF00067.22 KXX75838.1 - 1.7e-25 89.7 0.0 2e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_1 PF00190.22 KXX75839.1 - 2.1e-18 66.4 0.1 2.8e-18 65.9 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXX75839.1 - 5.9e-05 22.7 0.0 0.00022 20.9 0.0 1.8 1 1 0 1 1 1 1 Cupin domain Glyco_hydro_2_N PF02837.18 KXX75840.1 - 2e-14 53.9 0.1 7.7e-14 51.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KXX75840.1 - 6.9e-13 48.4 0.5 2.2e-12 46.7 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KXX75840.1 - 1.8e-11 44.7 0.0 4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 VIT PF08487.10 KXX75841.1 - 3.2e-36 123.9 0.0 7.5e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KXX75841.1 - 7e-23 81.3 0.0 1.7e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXX75841.1 - 1.7e-15 56.6 0.0 5.5e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain CorA PF01544.18 KXX75842.1 - 8.1e-13 48.3 0.1 4e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acyl-CoA_dh_1 PF00441.24 KXX75843.1 - 3.7e-33 114.8 1.7 7.1e-33 113.9 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXX75843.1 - 3.6e-20 72.0 0.0 6.6e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXX75843.1 - 3.9e-19 69.4 0.0 8.4e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXX75843.1 - 7.3e-15 55.4 3.7 3.3e-14 53.3 1.7 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain TPP1 PF10341.9 KXX75843.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Sulfotransfer_4 PF17784.1 KXX75845.1 - 2.4e-56 191.0 0.2 2.8e-56 190.7 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXX75845.1 - 0.018 15.4 0.7 0.064 13.6 0.1 2.0 1 1 0 2 2 2 0 Sulfotransferase family tRNA_bind PF01588.20 KXX75846.1 - 8e-23 80.4 0.1 2.1e-22 79.0 0.1 1.8 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KXX75846.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX75846.1 - 0.34 11.2 1.8 0.66 10.2 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Virulence_fact PF13769.6 KXX75846.1 - 0.65 10.3 3.3 1.5 9.1 3.3 1.6 1 0 0 1 1 1 0 Virulence factor SNF2_N PF00176.23 KXX75847.1 - 9e-65 218.7 0.2 1.9e-64 217.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX75847.1 - 5.4e-22 78.2 0.0 1.7e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX75847.1 - 5.1e-06 26.6 0.1 1.8e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXX75847.1 - 9.9e-06 24.9 0.9 2.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KXX75847.1 - 0.00023 20.5 0.5 0.047 12.9 0.0 3.1 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.6 KXX75847.1 - 3.4 8.0 11.8 0.49 10.8 6.8 2.1 2 0 0 2 2 2 0 DNA-binding domain DUF4710 PF15828.5 KXX75847.1 - 3.9 7.7 7.0 12 6.0 7.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Sld5 PF05916.11 KXX75848.1 - 4.2e-30 104.4 0.0 9e-30 103.3 0.0 1.6 2 0 0 2 2 2 1 GINS complex protein Glyco_hydro_61 PF03443.14 KXX75849.1 - 1.3e-55 188.5 0.1 1.6e-55 188.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_3 PF07859.13 KXX75850.1 - 1.2e-17 64.4 0.3 1.3e-16 61.1 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXX75850.1 - 4.9e-05 22.4 0.0 7.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 KXX75850.1 - 0.00073 18.3 0.0 0.43 9.2 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) COesterase PF00135.28 KXX75850.1 - 0.0011 18.0 0.0 0.019 13.8 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KXX75850.1 - 0.0011 18.3 0.2 0.42 9.8 0.0 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXX75850.1 - 0.0015 17.6 0.0 0.002 17.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Say1_Mug180 PF10340.9 KXX75850.1 - 0.0015 17.5 0.0 0.0075 15.2 0.0 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXX75850.1 - 0.0025 17.3 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXX75850.1 - 0.023 14.3 0.0 0.19 11.3 0.0 2.3 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KXX75850.1 - 0.043 13.4 0.0 5 6.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Ank_2 PF12796.7 KXX75851.1 - 4.1e-36 123.4 8.6 3.5e-11 43.5 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX75851.1 - 5.2e-27 93.9 3.5 8.3e-06 26.3 0.2 6.5 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX75851.1 - 2.5e-23 81.8 1.6 3.5e-07 30.4 0.0 5.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75851.1 - 1e-18 65.5 0.8 0.013 16.0 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KXX75851.1 - 2e-17 62.8 0.5 0.38 11.3 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeat Zn_clus PF00172.18 KXX75851.1 - 1.2 9.3 15.1 2.3 8.4 15.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KXX75852.1 - 2.1e-43 148.6 0.0 2.7e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C2H2_4 PF13894.6 KXX75854.1 - 2.4e-05 24.8 11.0 0.0072 17.1 3.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX75854.1 - 5.1e-05 23.5 11.4 0.00047 20.5 3.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KXX75854.1 - 0.0022 18.3 1.8 1.4 9.3 0.1 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KXX75854.1 - 0.011 16.0 3.2 0.37 11.2 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXX75854.1 - 0.025 14.9 5.2 2.4 8.5 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KXX75854.1 - 0.032 14.3 7.5 0.089 12.8 0.8 2.6 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 KXX75854.1 - 0.036 13.8 11.1 0.32 10.8 3.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Acyltransf_C PF16076.5 KXX75854.1 - 0.16 12.1 0.6 0.35 11.0 0.1 1.9 2 0 0 2 2 2 0 Acyltransferase C-terminus FOXP-CC PF16159.5 KXX75854.1 - 0.19 12.4 0.3 0.19 12.4 0.3 2.3 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF629 PF04780.12 KXX75854.1 - 0.87 8.0 5.2 4.6 5.6 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Pribosyltran_N PF13793.6 KXX75855.1 - 6.5e-43 145.4 0.5 1.6e-42 144.1 0.1 1.9 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXX75855.1 - 1.1e-40 139.7 2.5 3.9e-36 124.8 0.2 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXX75855.1 - 2.7e-14 53.0 0.8 4.5e-14 52.3 0.3 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXX75855.1 - 0.003 17.0 0.3 0.0059 16.1 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NTP_transf_3 PF12804.7 KXX75855.1 - 0.019 15.3 0.2 0.068 13.5 0.2 1.8 1 1 1 2 2 2 0 MobA-like NTP transferase domain AF2331-like PF14556.6 KXX75855.1 - 0.11 13.1 0.7 8.6 7.0 0.0 2.9 3 0 0 3 3 3 0 AF2331-like UPF0121 PF03661.13 KXX75856.1 - 2.1e-28 99.4 1.4 3.1e-28 98.8 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DSPc PF00782.20 KXX75856.1 - 5.1e-08 32.8 0.0 9.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXX75856.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Elong-fact-P_C PF09285.11 KXX75856.1 - 0.085 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P, C-terminal Y_phosphatase3 PF13350.6 KXX75856.1 - 0.11 12.4 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Rhodanese PF00581.20 KXX75857.1 - 3.5e-12 46.8 0.1 3.8e-11 43.5 0.1 2.0 1 1 0 1 1 1 1 Rhodanese-like domain DUF4448 PF14610.6 KXX75858.1 - 1.4e-20 73.9 0.0 7e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 KXX75858.1 - 0.0087 16.8 0.3 0.022 15.5 0.3 1.7 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Insulin_TMD PF17870.1 KXX75858.1 - 0.034 14.2 0.0 0.093 12.8 0.0 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment AAA_12 PF13087.6 KXX75859.1 - 6.3e-39 133.7 0.0 1.1e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXX75859.1 - 3.3e-24 86.1 0.0 6.1e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX75859.1 - 1.1e-08 35.5 0.0 8.5e-08 32.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXX75859.1 - 9.8e-06 25.4 0.0 0.002 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KXX75859.1 - 8.9e-05 21.9 0.1 0.3 10.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KXX75859.1 - 0.00092 19.0 0.5 0.068 12.9 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KXX75859.1 - 0.039 13.8 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KXX75859.1 - 0.046 14.0 0.1 0.67 10.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXX75859.1 - 0.065 12.3 0.1 0.31 10.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 KXX75859.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Fer4_20 PF14691.6 KXX75859.1 - 2.5 7.9 14.3 2.6 7.8 12.5 1.9 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Acetyltransf_1 PF00583.25 KXX75861.1 - 1.2e-12 48.0 0.0 2.5e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX75861.1 - 1.4e-08 35.0 0.0 3.6e-08 33.7 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX75861.1 - 1.7e-08 34.5 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX75861.1 - 0.0029 17.6 0.0 0.0065 16.4 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXX75861.1 - 0.0039 17.3 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXX75861.1 - 0.0096 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2686 PF10887.8 KXX75861.1 - 0.038 12.9 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) DUF4384 PF14326.6 KXX75861.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) ABC_membrane PF00664.23 KXX75862.1 - 2.2e-78 263.7 28.2 5.6e-40 137.7 1.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXX75862.1 - 9.6e-67 223.7 0.0 1.3e-32 113.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXX75862.1 - 6.2e-13 48.7 0.7 0.0017 17.8 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXX75862.1 - 7.8e-08 31.9 0.3 0.0079 15.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXX75862.1 - 6.7e-07 29.8 5.2 0.011 16.2 0.2 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXX75862.1 - 1.9e-06 28.2 0.8 0.14 12.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXX75862.1 - 2e-06 27.2 0.0 0.078 12.2 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.6 KXX75862.1 - 1.3e-05 25.1 0.7 0.98 9.2 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KXX75862.1 - 2.1e-05 23.6 0.5 0.063 12.1 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class APS_kinase PF01583.20 KXX75862.1 - 2.2e-05 24.4 2.7 0.0047 16.8 0.1 2.7 3 0 0 3 3 2 2 Adenylylsulphate kinase AAA_23 PF13476.6 KXX75862.1 - 6.3e-05 23.6 1.3 0.1 13.1 0.0 2.6 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KXX75862.1 - 8.5e-05 22.5 0.2 0.28 11.1 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_30 PF13604.6 KXX75862.1 - 0.00032 20.5 4.9 0.032 13.9 0.3 3.7 3 1 1 4 4 4 1 AAA domain DUF87 PF01935.17 KXX75862.1 - 0.00033 20.8 0.9 0.0097 16.0 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 KXX75862.1 - 0.00042 20.5 0.1 0.57 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXX75862.1 - 0.00081 19.2 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXX75862.1 - 0.0013 18.3 0.4 6.4 6.3 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 KXX75862.1 - 0.0015 19.1 0.3 1.2 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXX75862.1 - 0.0015 19.0 0.1 19 5.7 0.1 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KXX75862.1 - 0.0019 18.4 0.8 3.8 7.8 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KXX75862.1 - 0.0032 17.5 0.2 8.2 6.4 0.1 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KXX75862.1 - 0.0049 16.1 0.2 1.7 7.8 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.23 KXX75862.1 - 0.016 15.3 0.1 8.7 6.5 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KXX75862.1 - 0.028 14.5 0.0 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXX75862.1 - 0.057 12.9 0.4 12 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KXX75862.1 - 0.057 13.8 0.2 22 5.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KXX75862.1 - 0.15 11.2 0.0 12 5.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.6 KXX75862.1 - 0.22 11.2 0.0 3.4 7.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.18 KXX75862.1 - 0.3 10.8 1.2 5.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PRKCSH PF07915.13 KXX75863.1 - 8.7e-19 68.3 0.0 1.8e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF3086 PF11285.8 KXX75864.1 - 0.079 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) p450 PF00067.22 KXX75865.1 - 5.7e-66 223.2 0.0 7e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KXX75866.1 - 0.00017 22.0 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXX75867.1 - 3.4e-27 95.6 0.7 5.7e-27 94.9 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 KXX75868.1 - 1.1e-71 241.7 0.2 6.7e-71 239.1 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KXX75868.1 - 1.5e-64 218.4 0.0 3e-38 131.7 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KXX75868.1 - 5.1e-23 81.2 0.0 2.4e-10 40.6 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site HTH_Tnp_Tc5 PF03221.16 KXX75869.1 - 0.0026 17.7 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_7 PF02796.15 KXX75869.1 - 0.019 15.0 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 KXX75869.1 - 0.054 13.1 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 KXX75869.1 - 0.071 13.4 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.6 KXX75869.1 - 0.081 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 KXX75869.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain KR PF08659.10 KXX75870.1 - 3.6e-57 193.2 0.4 1e-28 100.5 0.0 2.8 2 0 0 2 2 2 2 KR domain ketoacyl-synt PF00109.26 KXX75870.1 - 9.9e-57 192.4 0.6 3.7e-43 147.9 0.3 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXX75870.1 - 1.3e-49 169.1 0.0 2.8e-49 168.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXX75870.1 - 1.3e-36 125.2 0.2 6.5e-36 122.9 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KXX75870.1 - 6.4e-34 117.9 0.2 1.5e-33 116.7 0.2 1.6 1 1 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KXX75870.1 - 1.8e-14 54.1 0.0 9.1e-14 51.9 0.0 2.2 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KXX75870.1 - 2.7e-12 46.8 0.7 8e-12 45.3 0.7 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXX75870.1 - 5.6e-07 29.2 0.4 2.4e-06 27.2 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KXX75870.1 - 2.3e-05 24.6 0.0 5.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KXX75870.1 - 0.0021 17.7 1.6 0.0023 17.6 0.0 2.0 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXX75870.1 - 0.0027 17.1 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KXX75870.1 - 0.0032 17.3 0.0 0.012 15.4 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N_2 PF13602.6 KXX75870.1 - 0.04 15.0 0.1 0.16 13.0 0.1 2.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX75870.1 - 0.087 12.7 0.2 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KXX75870.1 - 0.32 11.3 4.2 0.33 11.2 0.4 2.8 3 0 0 3 3 2 0 TrkA-N domain CAP_N PF01213.19 KXX75871.1 - 0.13 11.7 1.2 0.16 11.5 1.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MRC1 PF09444.10 KXX75872.1 - 7.9e-45 152.9 21.7 7.9e-45 152.9 21.7 8.7 7 2 0 8 8 8 1 MRC1-like domain Drf_GBD PF06371.13 KXX75872.1 - 2 7.9 4.2 7.4 6.1 4.1 2.0 1 1 0 1 1 1 0 Diaphanous GTPase-binding Domain DIRP PF06584.13 KXX75872.1 - 7.7 6.8 7.9 0.3 11.3 1.0 2.3 2 0 0 2 2 2 0 DIRP Porin_3 PF01459.22 KXX75873.1 - 4.3e-73 246.1 9.1 4.8e-73 245.9 9.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin OMP_b-brl PF13505.6 KXX75873.1 - 0.059 13.5 9.7 0.022 14.9 6.2 1.9 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Asn_synthase PF00733.21 KXX75874.1 - 1.4e-92 311.1 0.0 2.5e-54 185.3 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXX75874.1 - 9e-37 125.7 0.0 1.4e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXX75874.1 - 1.4e-27 96.5 0.0 2.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXX75874.1 - 4.2e-07 29.6 0.0 7.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXX75874.1 - 0.00059 19.0 0.0 0.0021 17.2 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Peptidase_M24 PF00557.24 KXX75875.1 - 3.6e-43 147.7 0.0 4.6e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 KXX75875.1 - 0.11 12.4 0.5 0.18 11.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) CCDC106 PF15794.5 KXX75875.1 - 0.59 9.8 4.5 1.1 8.9 4.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nefa_Nip30_N PF10187.9 KXX75875.1 - 1.5 9.2 7.3 3 8.2 7.3 1.4 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 PGA2 PF07543.12 KXX75875.1 - 4.8 7.2 10.2 3 7.8 7.9 1.8 1 1 0 1 1 1 0 Protein trafficking PGA2 AAA_18 PF13238.6 KXX75876.1 - 3.7e-05 24.3 0.0 0.00038 21.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KXX75876.1 - 0.00026 20.8 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KXX75876.1 - 0.00029 20.1 0.0 0.00041 19.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 KXX75876.1 - 0.0022 17.3 0.0 0.008 15.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KXX75876.1 - 0.0024 18.0 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXX75876.1 - 0.0032 16.6 0.0 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 KXX75876.1 - 0.013 15.9 0.1 0.05 14.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXX75876.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXX75876.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 KXX75876.1 - 0.098 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXX75876.1 - 0.12 12.8 0.1 0.51 10.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXX75876.1 - 0.14 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KXX75876.1 - 0.21 11.3 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase DnaJ PF00226.31 KXX75878.1 - 2.9e-19 68.9 0.4 4.3e-19 68.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain PRELI PF04707.14 KXX75879.1 - 1.5e-42 145.0 0.3 2e-42 144.7 0.3 1.1 1 0 0 1 1 1 1 PRELI-like family 2OG-FeII_Oxy_3 PF13640.6 KXX75880.1 - 9.6e-10 39.2 0.1 1.9e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aldo_ket_red PF00248.21 KXX75882.1 - 1.5e-72 244.3 0.0 1.6e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC1 PF03109.16 KXX75883.1 - 2.1e-31 108.6 0.0 3.6e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family MFS_1 PF07690.16 KXX75884.1 - 2.1e-31 109.2 59.0 3.2e-31 108.6 59.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX75884.1 - 9.7e-11 41.2 16.2 9.7e-11 41.2 16.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXX75884.1 - 2.1 6.5 14.3 0.042 12.1 3.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_76 PF03663.14 KXX75885.1 - 4.2e-157 523.4 8.7 4.9e-157 523.1 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXX75885.1 - 0.0078 15.3 8.9 0.084 11.9 0.3 3.1 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 GCP_C_terminal PF04130.13 KXX75886.1 - 2.8e-99 332.5 0.2 4.8e-99 331.7 0.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXX75886.1 - 6.7e-83 278.8 0.1 1.9e-82 277.4 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal SAGA-Tad1 PF12767.7 KXX75887.1 - 2.3e-63 214.1 0.0 3.1e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit UQ_con PF00179.26 KXX75888.1 - 1.1e-50 170.9 0.1 1.2e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX75888.1 - 4.1e-06 26.5 0.0 6.3e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXX75888.1 - 0.026 14.8 1.9 0.055 13.8 1.9 1.8 1 1 0 1 1 1 0 RWD domain SKG6 PF08693.10 KXX75889.1 - 4.1e-08 32.5 5.4 4.1e-08 32.5 5.4 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain VSP PF03302.13 KXX75889.1 - 0.021 13.7 0.2 0.021 13.7 0.2 1.7 2 0 0 2 2 2 0 Giardia variant-specific surface protein GAPT PF11770.8 KXX75889.1 - 0.24 11.3 0.1 0.4 10.5 0.1 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Amidohydro_2 PF04909.14 KXX75891.1 - 8.4e-08 32.3 0.1 1.2e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.20 KXX75891.1 - 1.1e-06 28.2 0.4 2.3e-06 27.2 0.4 1.6 1 1 0 1 1 1 1 Amidohydrolase family Fungal_trans PF04082.18 KXX75892.1 - 8.8e-28 97.1 0.0 1.6e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX75892.1 - 6.8e-06 26.1 15.4 1.2e-05 25.4 15.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.19 KXX75893.1 - 1.8e-16 60.1 8.9 2.9e-16 59.4 8.9 1.3 1 0 0 1 1 1 1 WSC domain DnaJ_C PF01556.18 KXX75894.1 - 1e-37 129.5 0.0 1.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXX75894.1 - 2.9e-28 97.8 2.5 4.9e-28 97.0 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXX75894.1 - 1.2e-15 57.6 18.0 2.3e-15 56.7 18.0 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXX75894.1 - 0.046 13.7 17.3 0.66 10.0 7.2 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXX75894.1 - 0.062 13.3 9.7 0.95 9.5 2.6 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C74 PF12387.8 KXX75894.1 - 0.2 11.1 0.8 0.39 10.2 0.8 1.4 1 0 0 1 1 1 0 Pestivirus NS2 peptidase DZR PF12773.7 KXX75894.1 - 0.61 10.2 5.8 5.3 7.2 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KXX75894.1 - 4.6 7.3 8.6 3.6e+02 1.2 8.6 2.5 1 1 0 1 1 1 0 zinc-ribbons Ank_4 PF13637.6 KXX75895.1 - 2.6e-15 56.6 0.6 0.00055 20.5 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX75895.1 - 1.4e-13 51.2 0.0 4.5e-08 33.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX75895.1 - 1.2e-08 35.0 0.1 0.0013 19.0 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.12 KXX75895.1 - 2.9e-08 33.8 0.0 7.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 KXX75895.1 - 7.5e-08 32.5 0.2 0.35 11.4 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat AAA_22 PF13401.6 KXX75895.1 - 2.5e-06 27.8 0.0 7.8e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX75895.1 - 8.3e-06 26.3 0.5 4.1e-05 24.0 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.6 KXX75895.1 - 1.7e-05 24.8 0.7 1.5 9.6 0.0 5.3 6 0 0 6 6 4 1 Ankyrin repeat AAA PF00004.29 KXX75895.1 - 0.0049 17.3 0.0 0.017 15.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KXX75895.1 - 0.021 14.2 0.0 0.08 12.3 0.0 1.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KXX75895.1 - 0.035 14.6 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KXX75895.1 - 0.04 14.3 0.0 0.17 12.3 0.0 2.1 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KXX75895.1 - 0.06 12.6 2.3 0.95 8.6 1.3 2.7 2 1 0 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.6 KXX75895.1 - 0.065 13.4 0.1 0.65 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXX75895.1 - 0.074 12.2 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MRI PF15325.6 KXX75896.1 - 4.2 8.5 12.8 2 9.5 3.1 2.7 2 1 0 2 2 2 0 Modulator of retrovirus infection Mito_carr PF00153.27 KXX75897.1 - 6.1e-65 215.2 0.3 2.6e-20 72.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXX75897.1 - 0.62 9.2 3.2 3.9 6.5 0.1 3.1 4 0 0 4 4 4 0 Gammaproteobacterial serine protease ApoO PF09769.9 KXX75898.1 - 6.7e-44 149.0 3.0 1.2e-42 144.9 0.1 2.7 3 0 0 3 3 3 2 Apolipoprotein O Med3 PF11593.8 KXX75898.1 - 0.57 9.3 6.7 0.69 9.0 6.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_M3 PF01432.20 KXX75899.1 - 6.6e-118 394.9 0.0 1.2e-117 394.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KXX75899.1 - 0.029 14.0 0.1 0.048 13.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Spore_III_AB PF09548.10 KXX75899.1 - 0.13 12.3 0.1 0.44 10.7 0.1 1.9 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) IMS PF00817.20 KXX75900.1 - 2.9e-40 137.7 0.0 5.9e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KXX75900.1 - 1.1e-26 93.1 4.3 2.3e-26 92.0 4.3 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 KXX75900.1 - 7.9e-16 56.9 11.2 4.1e-07 29.2 0.3 3.9 3 0 0 3 3 3 3 Ubiquitin binding region IMS_C PF11799.8 KXX75900.1 - 3.3e-14 53.6 0.0 7.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KXX75900.1 - 2.3e-07 31.2 0.0 9.2e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain mCpol PF18182.1 KXX75900.1 - 0.00088 19.6 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain MgtE_N PF03448.17 KXX75900.1 - 0.0015 19.1 0.1 12 6.6 0.0 4.1 4 0 0 4 4 4 1 MgtE intracellular N domain LIG3_BRCT PF16759.5 KXX75900.1 - 0.003 17.8 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 KXX75900.1 - 0.013 15.8 1.0 0.053 13.9 0.2 2.5 2 0 0 2 2 2 0 IMS family HHH motif DUF1805 PF08827.11 KXX75900.1 - 0.047 14.0 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FliG_M PF14841.6 KXX75900.1 - 0.2 11.9 0.9 77 3.6 0.0 3.9 4 0 0 4 4 4 0 FliG middle domain RED_N PF07808.13 KXX75901.1 - 1.8e-08 34.2 13.3 1.8e-08 34.2 13.3 2.7 2 1 0 2 2 2 1 RED-like protein N-terminal region DUF2924 PF11149.8 KXX75901.1 - 8.6 6.7 11.9 0.11 12.8 2.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2924) TFIIA PF03153.13 KXX75902.1 - 1.4e-05 25.3 12.4 1.9e-05 24.9 12.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit IFT57 PF10498.9 KXX75902.1 - 0.25 10.3 4.0 0.42 9.5 4.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Joubert PF15392.6 KXX75902.1 - 0.32 10.7 6.1 0.52 10.0 6.1 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated Nop14 PF04147.12 KXX75902.1 - 0.61 8.2 18.2 0.17 10.0 12.8 2.0 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 KXX75902.1 - 1 7.4 15.2 1.4 7.0 15.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SpoIIIAH PF12685.7 KXX75902.1 - 1.9 8.3 6.6 4.6 7.0 6.6 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein PPP4R2 PF09184.11 KXX75902.1 - 6.4 6.3 10.1 9.9 5.7 10.1 1.3 1 0 0 1 1 1 0 PPP4R2 Pkinase PF00069.25 KXX75903.1 - 2.6e-33 115.5 0.0 7.7e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75903.1 - 1.8e-11 43.9 0.0 6e-10 38.8 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXX75903.1 - 1.7e-06 28.1 0.0 3.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXX75903.1 - 0.0047 16.3 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like IU_nuc_hydro PF01156.19 KXX75904.1 - 8.1e-79 265.3 0.0 9.7e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF1660 PF07874.11 KXX75905.1 - 0.12 12.9 0.7 7 7.2 0.0 2.9 2 1 0 2 2 2 0 Prophage protein (DUF1660) CAP_GLY PF01302.25 KXX75906.1 - 3.1e-16 59.1 0.2 8.4e-16 57.8 0.2 1.8 2 0 0 2 2 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KXX75906.1 - 1.2e-06 28.2 9.1 0.00046 20.0 1.3 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle AAA_13 PF13166.6 KXX75906.1 - 0.00091 18.0 9.8 0.00091 18.0 9.8 2.1 2 1 0 2 2 2 1 AAA domain BLOC1_2 PF10046.9 KXX75906.1 - 0.0061 16.8 2.8 0.0061 16.8 2.8 3.6 4 0 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med4 PF10018.9 KXX75906.1 - 0.013 15.1 1.7 0.013 15.1 1.7 3.3 3 2 1 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.12 KXX75906.1 - 0.014 15.8 6.5 0.1 13.1 1.4 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Glutaredoxin2_C PF04399.13 KXX75906.1 - 0.051 13.4 3.3 4.9 7.0 0.7 2.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Spc7 PF08317.11 KXX75906.1 - 0.19 10.5 31.2 0.64 8.8 11.9 3.5 2 1 2 4 4 4 0 Spc7 kinetochore protein Pkip-1 PF06878.11 KXX75906.1 - 0.38 10.8 7.1 4.2 7.5 0.2 2.3 1 1 1 2 2 2 0 Pkip-1 protein DUF3584 PF12128.8 KXX75906.1 - 0.44 8.0 24.1 0.98 6.8 24.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 KXX75906.1 - 0.45 10.8 1.4 1.8 8.9 1.4 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 KXX75906.1 - 0.54 9.1 29.2 0.068 12.0 16.3 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 KXX75906.1 - 0.64 10.0 4.6 1 9.4 2.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.13 KXX75906.1 - 0.68 8.2 28.5 0.2 10.0 21.1 2.5 2 1 0 2 2 2 0 Mitotic checkpoint protein HrpB7 PF09486.10 KXX75906.1 - 0.91 9.9 31.9 7.4 6.9 18.4 3.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) zf_PR_Knuckle PF18445.1 KXX75906.1 - 1.9 8.4 4.1 13 5.7 0.3 2.4 2 0 0 2 2 2 0 PR zinc knuckle motif DASH_Dam1 PF08653.10 KXX75906.1 - 2.6 7.9 3.7 4.3 7.2 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Cauli_AT PF03233.13 KXX75906.1 - 3.7 7.5 4.4 1.7 8.5 1.4 2.0 2 0 0 2 2 2 0 Aphid transmission protein MscS_porin PF12795.7 KXX75906.1 - 4.2 6.9 25.7 0.91 9.0 9.1 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Glyco_hydro_38N PF01074.22 KXX75907.1 - 3.3e-88 295.8 0.6 6.3e-88 294.9 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KXX75907.1 - 8.9e-60 202.4 1.4 2.3e-59 201.1 0.6 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXX75907.1 - 5.8e-27 93.7 0.0 1.5e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXX75907.1 - 7.2e-08 32.4 0.0 2.9e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KXX75907.1 - 0.051 12.8 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 Nop14 PF04147.12 KXX75908.1 - 8.9e-304 1010.2 27.3 1.1e-303 1009.8 27.3 1.1 1 0 0 1 1 1 1 Nop14-like family MutS_V PF00488.21 KXX75909.1 - 3.8e-68 229.2 0.0 7.2e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXX75909.1 - 8.5e-51 172.9 5.6 1.6e-50 172.0 5.6 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXX75909.1 - 1.3e-18 67.3 0.0 4.9e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KXX75909.1 - 2e-10 41.1 0.0 4.6e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 KXX75909.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CCDC92 PF14916.6 KXX75909.1 - 0.067 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function AAA_23 PF13476.6 KXX75909.1 - 0.13 12.7 0.7 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KXX75910.1 - 0.0025 18.6 0.0 3 8.9 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF5640 PF18692.1 KXX75910.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5640) ORC6 PF05460.13 KXX75910.1 - 2.6 7.2 12.3 0.36 10.0 3.7 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_L10 PF00466.20 KXX75911.1 - 1.8e-23 82.6 0.2 4.9e-23 81.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KXX75911.1 - 5.2e-23 80.8 0.0 9.1e-23 80.1 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KXX75911.1 - 6.1e-15 55.6 7.3 8.2e-15 55.2 5.2 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 KXX75911.1 - 0.046 13.5 0.1 56 3.4 0.0 3.7 4 0 0 4 4 4 0 Pox virus Ag35 surface protein PCI PF01399.27 KXX75912.1 - 1.8e-07 31.6 0.1 1.8e-07 31.6 0.1 2.9 3 0 0 3 3 3 1 PCI domain G-gamma PF00631.22 KXX75913.1 - 8.3e-27 93.0 0.0 1.1e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 GGL domain Ribosomal_L11 PF00298.19 KXX75913.1 - 0.19 12.3 0.0 0.24 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Rdx PF10262.9 KXX75914.1 - 3.1e-33 113.8 0.0 4.2e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Rdx family SUKH-4 PF14435.6 KXX75914.1 - 0.26 11.3 3.7 0.37 10.8 2.0 1.9 1 1 1 2 2 2 0 SUKH-4 immunity protein Metallophos PF00149.28 KXX75915.1 - 4e-40 138.5 0.1 5.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXX75915.1 - 1e-22 80.3 2.4 1.4e-22 79.9 1.5 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain zf-C2H2 PF00096.26 KXX75916.1 - 4.4e-26 89.8 48.4 3.7e-05 23.9 0.1 11.2 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX75916.1 - 3.9e-18 64.6 51.9 0.057 14.3 0.3 11.2 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXX75916.1 - 1.2e-13 50.7 44.6 4.4e-05 23.7 0.8 11.1 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXX75916.1 - 5e-08 33.0 17.9 0.92 9.9 0.0 9.0 11 0 0 11 11 11 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXX75916.1 - 2e-07 31.5 29.5 0.1 13.2 0.1 8.5 6 2 4 10 10 9 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KXX75916.1 - 7.1e-07 29.5 13.6 0.00059 20.1 3.6 4.5 3 1 1 4 4 4 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KXX75916.1 - 0.0018 18.5 18.5 0.034 14.3 0.7 5.2 4 1 1 5 5 5 2 Aberrant zinc-finger DUF4187 PF13821.6 KXX75916.1 - 0.0069 16.1 1.0 0.064 13.0 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-met PF12874.7 KXX75916.1 - 0.042 14.3 18.1 8.3 7.0 0.0 7.2 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXX75916.1 - 0.15 11.8 21.3 8 6.3 0.0 7.1 7 0 0 7 7 7 0 zinc-finger C2H2-type Ogr_Delta PF04606.12 KXX75916.1 - 0.41 10.6 10.1 2.2 8.3 0.1 5.3 5 2 2 7 7 7 0 Ogr/Delta-like zinc finger PBP1_TM PF14812.6 KXX75916.1 - 0.47 10.8 5.0 0.75 10.2 1.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIE-A_C PF11521.8 KXX75916.1 - 0.88 9.9 5.1 33 4.9 3.5 2.7 3 0 0 3 3 2 0 C-terminal general transcription factor TFIIE alpha zf-C2H2_3rep PF18868.1 KXX75916.1 - 5.4 7.7 17.1 0.77 10.4 0.5 5.0 2 2 4 6 6 6 0 Zinc finger C2H2-type, 3 repeats RNA_pol_Rpb6 PF01192.22 KXX75917.1 - 1.4e-16 60.2 0.1 2.2e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Tautomerase_3 PF14832.6 KXX75918.1 - 2.6e-50 170.2 0.0 3e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme WSC PF01822.19 KXX75919.1 - 1.1e-32 112.1 23.7 3.2e-19 68.9 8.4 4.5 4 0 0 4 4 4 2 WSC domain zf-HC5HC2H_2 PF13832.6 KXX75920.1 - 7.2e-33 113.0 8.3 7.2e-33 113.0 8.3 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KXX75920.1 - 1.2e-29 103.7 0.4 5.9e-29 101.5 0.0 2.4 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KXX75920.1 - 2.8e-25 88.4 7.9 2.8e-25 88.4 7.9 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KXX75920.1 - 3.8e-14 52.0 1.9 3.8e-14 52.0 1.9 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXX75920.1 - 1.4e-08 34.5 9.5 1.4e-08 34.5 9.5 2.8 2 0 0 2 2 2 1 PHD-finger MATH PF00917.26 KXX75920.1 - 0.0088 16.2 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 1 MATH domain LRR_8 PF13855.6 KXX75921.1 - 1.2e-13 50.5 2.5 1.9e-08 33.9 2.0 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXX75921.1 - 8.1e-13 48.3 1.3 0.0005 20.4 0.7 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXX75921.1 - 6.6e-05 22.9 4.5 13 6.8 0.0 5.8 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 KXX75921.1 - 0.0036 16.8 1.0 0.38 10.2 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KXX75921.1 - 0.13 12.4 9.8 17 5.8 0.4 4.8 5 0 0 5 5 5 0 Leucine Rich repeat ICMT PF04140.14 KXX75922.1 - 1.2e-27 96.2 0.2 2.7e-27 95.0 0.2 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Tmemb_170 PF10190.9 KXX75922.1 - 3.6e-12 46.6 1.8 3.6e-12 46.6 1.8 3.2 4 1 0 4 4 4 1 Putative transmembrane protein 170 PEMT PF04191.13 KXX75922.1 - 2.4e-10 40.7 1.5 2.4e-10 40.7 1.5 3.0 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 KXX75922.1 - 0.00085 18.9 0.1 0.0017 17.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KXX75922.1 - 0.0015 18.0 0.2 0.0015 18.0 0.2 2.7 3 0 0 3 3 3 1 NnrU protein ERG4_ERG24 PF01222.17 KXX75922.1 - 0.0091 14.8 0.1 0.017 13.9 0.1 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MBOAT PF03062.19 KXX75924.1 - 2.4e-18 66.6 19.7 3.7e-18 66.0 19.7 1.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXX75924.1 - 0.0039 17.4 4.8 0.018 15.3 4.8 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 KXX75925.1 - 1.1e-30 105.2 24.7 1.3e-05 25.8 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX75925.1 - 2.4e-11 43.8 0.0 0.46 10.8 0.0 5.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXX75925.1 - 0.044 13.7 0.0 3.8 7.4 0.0 2.7 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KXX75925.1 - 0.071 11.8 0.0 0.15 10.7 0.0 1.5 1 0 0 1 1 1 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KXX75925.1 - 0.16 10.9 0.1 6 5.7 0.1 3.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Zip PF02535.22 KXX75926.1 - 1.5e-30 106.5 11.0 5.1e-20 72.0 6.2 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter MFS_1 PF07690.16 KXX75926.1 - 0.0048 15.9 20.5 0.081 11.8 2.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KXX75927.1 - 9.3e-09 35.0 2.2 0.0018 17.6 0.2 3.0 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KXX75927.1 - 0.00019 21.1 0.3 0.00042 20.0 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX75927.1 - 0.00032 20.9 0.1 0.00068 19.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX75927.1 - 0.006 15.8 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX75927.1 - 0.012 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXX75927.1 - 0.03 13.6 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX75927.1 - 0.06 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXX75927.1 - 0.11 11.2 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KXX75927.1 - 0.18 12.4 0.5 0.37 11.4 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S8 PF00082.22 KXX75931.1 - 1.2e-32 113.4 17.2 1.9e-32 112.7 17.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXX75931.1 - 1.6e-09 38.3 0.0 4.9e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 P19Arf_N PF07392.12 KXX75931.1 - 0.096 13.2 0.4 23 5.6 0.0 2.8 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus p450 PF00067.22 KXX75932.1 - 2.6e-47 161.6 0.0 3.1e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.21 KXX75933.1 - 1.5e-34 119.5 0.0 2.4e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KXX75933.1 - 7.6e-17 60.9 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1682 PF07946.14 KXX75933.1 - 0.55 9.4 2.8 0.95 8.6 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HTH_ABP1_N PF18107.1 KXX75935.1 - 0.022 14.5 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain RPA43_OB PF17875.1 KXX75936.1 - 2.8e-37 128.1 0.1 2.8e-37 128.1 0.1 3.4 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KXX75936.1 - 9.3e-08 32.3 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 PMI_typeI PF01238.21 KXX75937.1 - 2.6e-136 454.7 0.0 3.1e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KXX75937.1 - 0.0071 16.3 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain DUF1325 PF07039.11 KXX75938.1 - 3.4e-35 121.0 0.0 4.9e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KXX75938.1 - 0.092 12.6 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Atrophin-1 PF03154.15 KXX75938.1 - 0.53 8.5 4.1 0.81 7.9 4.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Arf PF00025.21 KXX75939.1 - 2.3e-73 245.4 0.0 2.6e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXX75939.1 - 3.8e-14 52.9 0.0 5.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXX75939.1 - 9e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXX75939.1 - 3.2e-12 46.3 1.0 8.3e-08 31.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXX75939.1 - 6.3e-12 45.4 0.0 6.9e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXX75939.1 - 3.9e-09 36.2 0.1 4.9e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXX75939.1 - 0.00037 20.5 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXX75939.1 - 0.0056 16.0 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Pkinase PF00069.25 KXX75940.1 - 2.5e-63 213.9 0.0 3.3e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX75940.1 - 5.2e-30 104.6 0.0 2.7e-29 102.2 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXX75940.1 - 0.0093 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXX75940.1 - 0.096 12.6 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXX75940.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Actin PF00022.19 KXX75941.1 - 5.4e-112 374.4 0.0 3.4e-111 371.8 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXX75941.1 - 0.026 13.3 0.0 0.17 10.7 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Asp_Glu_race PF01177.22 KXX75942.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.3 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Sugar_tr PF00083.24 KXX75943.1 - 2.8e-83 280.3 19.3 3.8e-82 276.6 19.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX75943.1 - 2.6e-35 122.0 55.2 1.8e-29 102.8 29.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX75943.1 - 3.5e-08 32.3 4.0 3.5e-08 32.3 4.0 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KXX75943.1 - 1.2e-06 28.1 8.7 1.2e-06 28.1 8.7 2.7 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Glyco_hydro_38 PF18438.1 KXX75943.1 - 0.041 13.9 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 NmrA PF05368.13 KXX75944.1 - 8.6e-33 113.8 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX75944.1 - 2.4e-12 47.1 0.1 9.7e-12 45.2 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXX75944.1 - 2e-06 27.5 0.1 5.7e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX75944.1 - 3.8e-06 26.1 0.0 6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXX75944.1 - 6.9e-05 22.8 0.1 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KXX75944.1 - 0.00032 21.1 0.1 0.0008 19.8 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXX75944.1 - 0.00084 19.6 0.1 0.0018 18.5 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXX75944.1 - 0.0027 16.9 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX75944.1 - 0.0032 16.9 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXX75944.1 - 0.0041 16.6 0.3 0.0066 15.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KXX75944.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein TrkA_N PF02254.18 KXX75944.1 - 0.015 15.5 0.0 0.042 14.1 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 KXX75944.1 - 0.023 15.3 0.1 0.15 12.6 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 KXX75944.1 - 0.07 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KXX75944.1 - 0.085 13.6 0.1 0.18 12.6 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase AMP-binding PF00501.28 KXX75946.1 - 1.1e-65 221.9 0.0 1.4e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX75946.1 - 5.4e-08 33.7 0.3 2.8e-07 31.4 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KXX75947.1 - 4.1e-28 98.3 22.2 4.8e-28 98.1 22.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX75947.1 - 7.6e-15 54.7 8.5 1.3e-14 54.0 7.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXX75947.1 - 2.9e-09 35.9 4.4 4.4e-09 35.3 4.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EMP70 PF02990.16 KXX75947.1 - 0.02 13.6 1.0 0.032 12.9 0.1 1.8 2 1 1 3 3 3 0 Endomembrane protein 70 Trypsin_2 PF13365.6 KXX75948.1 - 8.2e-28 98.2 0.1 1.2e-27 97.7 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 KXX75948.1 - 0.025 13.2 0.0 0.3 9.7 0.1 2.0 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.13 KXX75948.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_C4 PF00863.19 KXX75948.1 - 0.14 11.4 0.0 0.56 9.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C4 PhoD PF09423.10 KXX75950.1 - 1.1e-105 353.5 3.1 1.5e-105 353.1 3.1 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KXX75950.1 - 1.5e-31 108.8 0.2 3.7e-31 107.5 0.2 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KXX75950.1 - 4.8e-05 23.9 3.2 0.00019 21.9 3.3 2.0 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain CorA PF01544.18 KXX75951.1 - 2.3e-21 76.4 9.1 1.8e-18 66.9 5.3 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Ank_2 PF12796.7 KXX75952.1 - 9e-67 221.7 12.0 1e-11 45.2 0.0 9.9 3 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX75952.1 - 2.3e-44 149.2 5.6 1.2e-07 32.2 0.0 11.4 8 4 4 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX75952.1 - 4.7e-44 147.9 5.7 0.0014 18.9 0.0 12.4 9 3 3 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX75952.1 - 1.1e-43 142.1 2.3 0.0009 19.5 0.0 14.2 14 0 0 14 14 14 11 Ankyrin repeat Ank PF00023.30 KXX75952.1 - 7.6e-42 140.0 3.9 0.00041 20.7 0.0 13.5 14 0 0 14 14 14 10 Ankyrin repeat Fungal_trans PF04082.18 KXX75953.1 - 3.5e-12 45.9 0.0 7.8e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX75953.1 - 0.00012 22.2 8.1 0.00012 22.2 8.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lenti_VIF_2 PF07401.12 KXX75953.1 - 0.036 13.4 0.2 0.22 10.9 0.0 2.2 3 0 0 3 3 3 0 Bovine Lentivirus VIF protein Kelch_6 PF13964.6 KXX75954.1 - 1.3e-13 50.7 8.8 0.00045 20.4 0.2 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KXX75954.1 - 6.7e-13 48.4 12.1 0.0018 18.2 0.2 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXX75954.1 - 1.6e-10 40.7 8.7 0.0028 17.6 0.0 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 KXX75954.1 - 3.7e-10 39.2 5.8 0.17 11.5 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KXX75954.1 - 4.9e-05 23.1 3.4 0.65 10.1 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KXX75954.1 - 0.00036 20.8 15.1 0.017 15.4 0.3 5.3 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF1524 PF07510.11 KXX75955.1 - 8.1e-06 25.8 0.0 9.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) PGAP1 PF07819.13 KXX75956.1 - 6.5e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 KXX75956.1 - 0.0034 17.0 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KXX75956.1 - 0.048 14.3 0.3 0.12 13.0 0.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 KXX75956.1 - 0.062 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RdRP PF05183.12 KXX75957.1 - 8.7e-45 153.4 0.0 1.2e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KXX75957.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 KXX75958.1 - 2.5e-63 214.4 0.0 7.3e-62 209.6 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 SnoaL_2 PF12680.7 KXX75959.1 - 1.3e-05 25.7 0.0 2.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Zn_clus PF00172.18 KXX75960.1 - 9.9e-08 32.0 9.7 2e-07 31.0 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.12 KXX75961.1 - 2.9e-88 297.0 0.0 3.5e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase EAL PF00563.20 KXX75961.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 EAL domain DIOX_N PF14226.6 KXX75962.1 - 1.2e-28 100.2 0.0 2e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXX75962.1 - 2.9e-20 72.6 0.0 4.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.19 KXX75963.1 - 2.9e-12 46.5 0.0 6.8e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXX75963.1 - 0.00078 18.6 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.24 KXX75963.1 - 0.016 14.5 0.1 0.26 10.5 0.0 2.3 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_4 PF01565.23 KXX75964.1 - 2e-23 82.7 2.3 4.5e-23 81.5 2.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX75964.1 - 1.7e-11 44.0 2.1 3.1e-11 43.2 2.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXX75964.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.22 KXX75965.1 - 5.1e-29 101.3 0.0 8.3e-28 97.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.22 KXX75966.1 - 8.4e-20 71.8 0.1 1.7e-19 70.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXX75966.1 - 0.022 15.2 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.18 KXX75967.1 - 2.6e-06 27.4 9.0 4.1e-06 26.8 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRTM1 PF15872.5 KXX75967.1 - 0.012 15.8 0.1 0.03 14.5 0.1 1.7 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 UPF0506 PF11703.8 KXX75967.1 - 0.1 13.0 4.4 0.21 12.0 4.4 1.4 1 0 0 1 1 1 0 UPF0506 AMP-binding PF00501.28 KXX75968.1 - 8.5e-73 245.3 0.0 1.4e-72 244.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KXX75968.1 - 1.3e-72 244.4 0.0 3.2e-72 243.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KXX75968.1 - 9e-64 215.8 0.0 1.7e-63 214.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KXX75968.1 - 3.6e-51 174.2 0.0 5.8e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXX75968.1 - 2.3e-49 167.7 0.0 5.9e-48 163.1 0.0 3.1 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KXX75968.1 - 5.4e-34 118.1 0.2 1.4e-33 116.8 0.2 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX75968.1 - 6.7e-32 110.0 0.0 1.8e-31 108.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXX75968.1 - 6.9e-26 90.9 0.0 3.2e-25 88.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXX75968.1 - 6.8e-21 74.4 0.6 2.7e-10 40.5 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXX75968.1 - 1.4e-14 54.5 0.0 3.7e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KXX75968.1 - 1e-11 45.4 0.0 4.5e-11 43.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXX75968.1 - 3e-10 40.0 0.0 1.7e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXX75968.1 - 1.6e-08 34.2 0.0 6.7e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KXX75968.1 - 1.9e-08 34.4 0.0 4.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX75968.1 - 9.7e-08 32.6 0.0 2.1e-06 28.3 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX75968.1 - 2.3e-07 30.7 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX75968.1 - 3.1e-07 31.0 0.0 2.5e-06 28.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 KXX75968.1 - 6.6e-05 22.4 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KXX75968.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXX75968.1 - 0.039 13.0 0.0 5.8 5.8 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 KXX75968.1 - 0.066 12.5 0.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Tropomyosin_1 PF12718.7 KXX75968.1 - 0.25 11.5 0.4 0.52 10.5 0.4 1.4 1 0 0 1 1 1 0 Tropomyosin like FAD_binding_4 PF01565.23 KXX75969.1 - 2.5e-12 46.7 0.6 4.7e-12 45.8 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 KXX75970.1 - 2.5e-66 224.3 0.0 3.1e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S9 PF00326.21 KXX75972.1 - 2.3e-42 144.9 0.0 3.8e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXX75972.1 - 5.2e-07 29.2 0.2 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 KXX75972.1 - 1.1e-05 25.3 1.9 0.15 12.0 0.5 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 KXX75972.1 - 1.7e-05 24.6 0.2 0.077 12.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KXX75972.1 - 5.3e-05 22.9 0.0 0.0002 21.0 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KXX75972.1 - 0.00012 21.8 0.1 0.19 11.3 0.4 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KXX75972.1 - 0.00022 21.2 0.0 0.0025 17.8 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Gmad1 PF10647.9 KXX75972.1 - 0.00035 20.4 0.8 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Abhydrolase_4 PF08386.10 KXX75972.1 - 0.0029 17.7 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 KXX75972.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXX75972.1 - 0.022 14.6 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KXX75972.1 - 0.023 14.2 2.6 0.033 13.7 0.6 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 KXX75972.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_GDSL_2 PF13472.6 KXX75973.1 - 3.5e-20 73.1 2.3 8.8e-20 71.8 2.3 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX75973.1 - 5.3e-08 33.1 0.0 7.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 KXX75974.1 - 2.2e-37 128.8 50.0 4.3e-37 127.9 44.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX75974.1 - 2.4e-13 49.4 15.6 3.2e-13 49.0 15.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.23 KXX75975.1 - 1e-17 64.2 0.6 2e-17 63.2 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX75975.1 - 8.5e-07 29.0 0.1 2.3e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like zf-C2H2_2 PF12756.7 KXX75976.1 - 1.9e-22 79.5 1.6 3.7e-22 78.5 1.6 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) GFA PF04828.14 KXX75977.1 - 1.6e-09 38.0 1.0 3.4e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.7 KXX75978.1 - 0.00054 19.8 0.8 0.001 18.9 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXX75978.1 - 0.0013 18.6 0.1 0.0032 17.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain Methyltransf_2 PF00891.18 KXX75979.1 - 1.7e-17 63.5 0.1 2.6e-17 62.8 0.1 1.3 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KXX75979.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF4211 PF13926.6 KXX75980.1 - 1.6e-47 161.2 0.0 4.4e-47 159.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF35_N PF12172.8 KXX75980.1 - 0.21 11.5 0.4 0.42 10.6 0.4 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pes-10 PF07149.11 KXX75980.1 - 9.8 5.1 6.6 18 4.2 6.6 1.4 1 0 0 1 1 1 0 Pes-10 Aminotran_1_2 PF00155.21 KXX75981.1 - 1.2e-59 202.3 0.0 1.6e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXX75981.1 - 0.17 11.1 0.0 0.59 9.4 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.28 KXX75982.1 - 6.9e-42 143.5 0.0 9.5e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXX75982.1 - 1.3e-09 37.8 1.3 6.3e-09 35.6 0.2 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXX75982.1 - 8.1e-05 23.5 2.1 9.9e-05 23.2 0.2 2.1 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 KXX75983.1 - 7e-07 29.3 11.3 1.1e-06 28.7 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Stm1_N PF09598.10 KXX75983.1 - 5.1 8.0 7.2 4.1 8.3 1.4 2.9 2 0 0 2 2 2 0 Stm1 YEATS PF03366.16 KXX75984.1 - 1.9e-21 75.8 0.1 3.9e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KXX75984.1 - 3e-05 24.1 0.1 6e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF4382 PF14321.6 KXX75984.1 - 0.064 13.5 0.0 0.27 11.5 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4382) Baculo_8kDa PF06096.11 KXX75984.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein Ran_BP1 PF00638.18 KXX75985.1 - 2.1e-49 166.8 0.8 3.9e-49 166.0 0.8 1.4 1 0 0 1 1 1 1 RanBP1 domain VID27_PH PF17747.1 KXX75985.1 - 0.015 15.5 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 VID27 PH-like domain PS-DH PF14765.6 KXX75985.1 - 0.016 14.5 0.3 0.016 14.5 0.3 1.8 2 0 0 2 2 2 0 Polyketide synthase dehydratase eIF-3c_N PF05470.12 KXX75985.1 - 0.31 9.3 6.9 0.44 8.8 6.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 KXX75985.1 - 0.43 9.9 6.2 0.66 9.2 6.2 1.3 1 0 0 1 1 1 0 NOA36 protein Phosducin PF02114.16 KXX75987.1 - 1.6e-11 43.7 0.3 3.5e-10 39.3 0.1 2.5 1 1 0 1 1 1 1 Phosducin DUF2235 PF09994.9 KXX75987.1 - 0.17 11.2 0.3 1.1 8.5 0.3 2.0 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_S10 PF00450.22 KXX75988.1 - 9.6e-130 433.7 1.0 1.2e-129 433.5 1.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KXX75988.1 - 2e-13 51.0 0.1 4.2e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide PDEase_I PF00233.19 KXX75989.1 - 1e-65 221.8 0.0 1.5e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_S13 PF00416.22 KXX75990.1 - 1.9e-55 186.7 2.5 2.2e-55 186.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KXX75990.1 - 0.012 14.3 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KXX75990.1 - 0.047 13.9 0.3 0.17 12.2 0.1 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif DUF2746 PF10874.8 KXX75990.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) SBDS_C PF09377.10 KXX75991.1 - 1.6e-47 160.3 0.0 2.4e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KXX75991.1 - 2e-35 120.7 0.1 3.2e-35 120.1 0.1 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UCH PF00443.29 KXX75992.1 - 4.5e-67 226.3 0.0 6.4e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX75992.1 - 8.4e-11 42.0 0.0 0.0019 17.9 0.0 3.4 2 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KXX75992.1 - 4e-06 27.4 0.0 9.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 DUSP domain Zn_ribbon_SprT PF17283.2 KXX75992.1 - 4.1 7.4 5.1 0.54 10.2 0.9 1.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain SAM_2 PF07647.17 KXX75993.1 - 4.3e-16 58.8 0.0 8.3e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXX75993.1 - 5e-14 52.5 0.0 9.3e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXX75993.1 - 4.5e-11 43.2 0.0 9.4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KXX75993.1 - 0.0072 16.3 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4173 PF13777.6 KXX75995.1 - 0.37 10.2 13.7 1.3 8.4 3.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4173) Aldo_ket_red PF00248.21 KXX75996.1 - 4.1e-10 39.3 0.0 6.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_60s PF00428.19 KXX75996.1 - 0.022 15.4 4.6 0.22 12.1 5.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein 4F5 PF04419.14 KXX75997.1 - 2.2e-10 41.2 11.7 2.2e-10 41.2 11.7 2.4 1 1 1 2 2 2 1 4F5 protein family SASP_gamma PF04259.14 KXX75997.1 - 0.038 14.5 6.1 0.042 14.3 6.1 1.2 1 0 0 1 1 1 0 Small, acid-soluble spore protein, gamma-type DFRP_C PF16543.5 KXX75997.1 - 0.33 11.5 6.2 0.46 11.0 6.2 1.3 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 CTD_bind PF04818.13 KXX75998.1 - 1.3e-05 25.9 0.0 2.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 KXX75998.1 - 7.5e-05 23.1 0.7 0.075 13.5 0.1 2.4 2 0 0 2 2 2 2 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 KXX75998.1 - 0.11 12.3 0.3 0.53 10.1 0.0 2.1 2 1 0 2 2 2 0 VHS domain zf-C2H2_4 PF13894.6 KXX75998.1 - 0.12 13.3 3.9 2.5 9.2 0.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 KXX75998.1 - 0.2 11.3 6.6 0.61 9.7 2.3 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Myb_DNA-binding PF00249.31 KXX76000.1 - 8.7e-15 54.6 3.5 3.8e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXX76000.1 - 1.2e-05 25.4 3.4 0.0044 17.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SMN PF06003.12 KXX76001.1 - 0.016 14.4 7.8 0.18 11.0 0.3 2.9 1 1 0 2 2 2 0 Survival motor neuron protein (SMN) Chalcone_2 PF16035.5 KXX76001.1 - 0.059 13.2 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Chalcone isomerase like GFO_IDH_MocA PF01408.22 KXX76003.1 - 6.9e-18 65.6 0.2 1.3e-17 64.8 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXX76003.1 - 0.00077 20.1 0.1 0.0013 19.4 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OpuAC PF04069.12 KXX76003.1 - 0.018 14.6 0.1 35 3.9 0.0 3.4 4 0 0 4 4 4 0 Substrate binding domain of ABC-type glycine betaine transport system Methyltransf_11 PF08241.12 KXX76004.1 - 1.3e-11 45.0 0.0 4.4e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX76004.1 - 2e-10 41.2 0.3 1.4e-08 35.3 0.3 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX76004.1 - 8.3e-08 32.9 0.0 2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX76004.1 - 4.8e-06 26.5 0.0 8.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX76004.1 - 2.5e-05 24.1 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain DUF2188 PF09954.9 KXX76004.1 - 8 6.7 11.6 0.76 10.0 0.9 3.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Chorion_2 PF03964.15 KXX76004.1 - 9 7.2 18.8 7.3 7.5 0.5 3.0 3 0 0 3 3 3 0 Chorion family 2 Citrate_synt PF00285.21 KXX76005.1 - 2.9e-101 339.1 0.0 4.1e-101 338.6 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KXX76005.1 - 0.031 14.0 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone CTD_bind PF04818.13 KXX76006.1 - 4.1e-09 37.1 0.0 8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KXX76006.1 - 2.7e-07 30.3 0.1 4.9e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E1-E2_ATPase PF00122.20 KXX76007.1 - 6.8e-48 162.6 5.4 6.8e-48 162.6 5.4 3.3 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KXX76007.1 - 3.4e-17 63.4 0.0 9.5e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX76007.1 - 4.1e-10 39.2 0.2 1.2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXX76007.1 - 0.0021 17.9 0.1 0.0046 16.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXX76007.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2613 PF11021.8 KXX76007.1 - 2.2 8.5 6.2 12 6.1 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) O-antigen_lig PF13425.6 KXX76007.1 - 2.7 6.7 10.4 1.1 8.0 6.6 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Mito_carr PF00153.27 KXX76008.1 - 2.8e-29 100.9 4.4 1.3e-13 50.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3425 PF11905.8 KXX76009.1 - 4.2e-21 75.2 0.1 7.7e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FGGY_C PF02782.16 KXX76010.1 - 2.5e-49 167.7 0.1 3.6e-49 167.2 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXX76010.1 - 1.8e-11 44.1 0.1 2e-08 34.1 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Nic96 PF04097.14 KXX76011.1 - 2.2e-229 763.1 0.0 2.7e-229 762.7 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Peptidase_C14 PF00656.22 KXX76012.1 - 0.00039 20.4 0.0 0.00095 19.2 0.0 1.6 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KXX76012.1 - 0.0011 19.0 0.0 0.0037 17.2 0.0 1.9 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain zf-TRAF PF02176.18 KXX76012.1 - 0.0043 17.7 1.3 0.014 16.1 1.3 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C2H2 PF00096.26 KXX76012.1 - 0.034 14.6 23.5 0.078 13.5 1.6 4.4 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX76012.1 - 0.077 13.9 20.9 0.089 13.7 1.9 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger Pex19 PF04614.12 KXX76012.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Pex19 protein family Sina PF03145.16 KXX76012.1 - 0.27 11.2 3.8 0.5 10.3 3.8 1.4 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_jaz PF12171.8 KXX76012.1 - 2.7 8.4 6.1 10 6.6 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ThuA PF06283.11 KXX76013.1 - 1.1e-55 189.1 0.0 1.3e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation Abhydrolase_3 PF07859.13 KXX76014.1 - 1.6e-19 70.6 0.0 1.3e-16 61.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX76014.1 - 1.9e-08 34.0 0.0 4.8e-05 22.9 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KXX76014.1 - 0.0059 15.5 0.0 0.014 14.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family CBM_1 PF00734.18 KXX76015.1 - 4.7e-11 42.4 11.5 4.7e-11 42.4 11.5 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.12 KXX76015.1 - 0.0023 16.6 0.0 0.0041 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Bestrophin PF01062.21 KXX76016.1 - 6.2e-33 114.4 0.0 1.2e-32 113.5 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PHO4 PF01384.20 KXX76016.1 - 0.018 14.1 0.2 0.055 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphate transporter family Aminotran_5 PF00266.19 KXX76018.1 - 1.1e-36 126.6 0.0 1.8e-23 83.1 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Zn_clus PF00172.18 KXX76019.1 - 1.6e-16 60.2 24.1 2.8e-08 33.7 6.9 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX76019.1 - 6e-14 51.7 0.1 9.1e-14 51.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PARP PF00644.20 KXX76020.1 - 1.7e-59 200.7 0.0 5.1e-59 199.1 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KXX76020.1 - 1.2e-33 116.1 0.4 9.4e-32 109.9 0.4 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KXX76020.1 - 4.2e-26 90.8 0.9 9.9e-26 89.6 0.9 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KXX76020.1 - 2.7e-13 50.1 0.0 4.8e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXX76020.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KXX76020.1 - 0.00059 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KXX76020.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTPS PF01242.19 KXX76020.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Dicty_REP PF05086.12 KXX76020.1 - 5.1 4.9 4.2 7.4 4.4 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_31 PF01055.26 KXX76023.1 - 3.2e-159 530.9 0.5 3.9e-159 530.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXX76023.1 - 8.1e-40 135.6 0.0 1.4e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXX76023.1 - 1e-14 54.6 1.8 5.7e-14 52.2 1.4 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_6 PF01341.17 KXX76024.1 - 1.3e-101 340.4 0.0 1.6e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KXX76024.1 - 2.9e-14 52.7 16.3 2.9e-14 52.7 16.3 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KXX76024.1 - 0.05 13.9 5.4 0.14 12.5 5.4 1.7 1 0 0 1 1 1 0 Toxin 7 PLDc_2 PF13091.6 KXX76025.1 - 5.4e-22 78.1 0.0 1.1e-13 51.3 0.0 3.4 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXX76025.1 - 2.4e-05 24.3 0.3 0.021 15.0 0.1 2.8 3 0 0 3 3 3 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KXX76025.1 - 0.089 12.0 0.1 2.8 7.0 0.0 3.0 4 0 0 4 4 4 0 Archaeal transcriptional regulator TrmB DUF2183 PF09949.9 KXX76026.1 - 6.5e-33 113.0 0.0 1.4e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Phenol_Hydrox PF02332.18 KXX76026.1 - 0.18 11.4 0.1 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Methane/Phenol/Toluene Hydroxylase UvdE PF03851.14 KXX76027.1 - 1.2e-115 385.5 0.0 1.6e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Cupin_2 PF07883.11 KXX76028.1 - 3.8e-16 58.6 0.2 6.7e-16 57.8 0.2 1.4 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 KXX76028.1 - 7.4e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.19 KXX76028.1 - 8.7e-05 22.4 0.1 0.00011 22.1 0.1 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXX76028.1 - 0.00029 20.5 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KXX76028.1 - 0.0015 18.3 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXX76028.1 - 0.0074 16.0 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) JmjC PF02373.22 KXX76028.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase GPI PF06560.11 KXX76028.1 - 0.044 13.1 0.1 0.15 11.3 0.0 1.9 1 1 1 2 2 2 0 Glucose-6-phosphate isomerase (GPI) GST_C_3 PF14497.6 KXX76029.1 - 2.8e-32 110.9 0.0 4.4e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX76029.1 - 7.8e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXX76029.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_43 PF04616.14 KXX76030.1 - 2.4e-36 125.6 0.6 2.9e-36 125.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 KXX76030.1 - 0.055 13.1 0.2 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat Nucleos_tra2_C PF07662.13 KXX76031.1 - 1.2e-68 231.1 0.2 1.2e-68 231.1 0.2 2.4 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KXX76031.1 - 2.4e-20 72.9 3.4 2.4e-20 72.9 3.4 3.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus HET PF06985.11 KXX76032.1 - 1.4e-26 93.6 1.9 8.3e-26 91.1 1.6 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.14 KXX76033.1 - 5.4e-42 144.1 4.0 6.2e-42 143.9 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HET PF06985.11 KXX76034.1 - 2.5e-33 115.5 0.0 5.1e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MLTR_LBD PF17765.1 KXX76034.1 - 0.076 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain PNK3P PF08645.11 KXX76035.1 - 3.9e-56 189.2 0.0 5.9e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KXX76035.1 - 6.4e-28 97.7 0.0 2e-14 54.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain APS_kinase PF01583.20 KXX76035.1 - 0.0076 16.2 0.0 0.1 12.5 0.0 2.3 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_29 PF13555.6 KXX76035.1 - 0.032 14.0 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXX76035.1 - 0.09 12.0 0.0 0.7 9.1 0.0 2.2 2 1 1 3 3 3 0 Zeta toxin AAA_23 PF13476.6 KXX76035.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX76035.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.24 KXX76036.1 - 1.9e-106 356.7 17.8 2.2e-106 356.4 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX76036.1 - 1.2e-28 100.1 39.6 5.9e-25 87.9 20.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KXX76037.1 - 4.1e-22 78.6 0.1 5.3e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76037.1 - 3.1e-18 66.2 0.1 5.2e-18 65.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76037.1 - 1.1e-09 38.4 0.1 1.9e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXX76037.1 - 0.013 14.7 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXX76037.1 - 0.028 13.9 1.6 0.23 10.9 1.6 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.19 KXX76038.1 - 2.6e-59 201.0 0.0 3.3e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX76038.1 - 1.6e-29 103.2 0.1 3.2e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX76038.1 - 2.5e-08 33.4 0.4 3.8e-07 29.5 0.2 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXX76038.1 - 1.9e-05 24.8 0.0 6.4e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX76038.1 - 7.4e-05 22.0 0.1 0.00011 21.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXX76038.1 - 0.00042 20.0 0.2 0.015 14.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX76038.1 - 0.0039 16.5 0.1 0.0064 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXX76038.1 - 0.039 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KXX76038.1 - 0.048 12.9 0.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX76038.1 - 0.22 10.7 1.3 1.8 7.7 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase BBE PF08031.12 KXX76040.1 - 4.7e-08 33.0 0.0 7.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KXX76041.1 - 4.2e-21 75.1 1.0 8.5e-21 74.2 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX76041.1 - 1.7e-12 47.2 0.2 4.4e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXX76041.1 - 0.23 10.8 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding SOSSC PF15925.5 KXX76042.1 - 0.1 13.9 1.1 0.33 12.3 0.1 2.3 2 0 0 2 2 2 0 SOSS complex subunit C Glyco_hydro_10 PF00331.20 KXX76043.1 - 1.8e-97 326.3 0.1 2.1e-97 326.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.24 KXX76043.1 - 0.013 15.0 0.0 0.033 13.6 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel WI12 PF07107.11 KXX76043.1 - 0.091 12.9 0.2 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Wound-induced protein WI12 Hemerythrin PF01814.23 KXX76044.1 - 4.9e-05 24.0 1.7 8.4e-05 23.2 1.1 1.7 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF3014 PF11219.8 KXX76044.1 - 0.027 14.7 0.0 0.049 13.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3014) ILVD_EDD PF00920.21 KXX76045.1 - 5.2e-153 510.4 0.1 5.9e-153 510.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family HepII_C PF18675.1 KXX76045.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Heparinase II C-terminal domain Abhydrolase_6 PF12697.7 KXX76046.1 - 2.7e-08 34.7 4.2 4.3e-08 34.0 4.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX76046.1 - 2.4e-06 27.4 0.2 4.6e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX76046.1 - 0.0062 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KXX76046.1 - 0.008 16.3 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DUF1057 PF06342.12 KXX76046.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) p450 PF00067.22 KXX76047.1 - 2.4e-50 171.7 0.0 3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ScsC_N PF18312.1 KXX76047.1 - 0.029 14.2 1.5 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain GMC_oxred_N PF00732.19 KXX76048.1 - 1.6e-60 205.0 0.0 2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX76048.1 - 4.4e-05 24.0 0.0 0.00013 22.5 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXX76048.1 - 0.00036 19.7 0.0 0.0028 16.8 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KXX76048.1 - 0.00038 19.8 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXX76048.1 - 0.0041 16.8 0.1 0.059 12.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX76048.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXX76048.1 - 0.016 15.2 0.1 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXX76048.1 - 0.041 12.9 0.0 0.041 12.9 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.14 KXX76048.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXX76048.1 - 0.12 12.6 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KXX76048.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase But2 PF09792.9 KXX76049.1 - 0.0003 21.2 0.1 0.00065 20.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain FAD_binding_4 PF01565.23 KXX76050.1 - 4.9e-24 84.7 0.2 8.3e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX76050.1 - 6.3e-05 23.0 0.2 0.00017 21.6 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cupin_4 PF08007.12 KXX76052.1 - 0.083 12.3 0.0 0.094 12.2 0.0 1.0 1 0 0 1 1 1 0 Cupin superfamily protein HasA PF06438.12 KXX76053.1 - 0.094 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Heme-binding protein A (HasA) UbiA PF01040.18 KXX76054.1 - 6.4e-32 110.8 24.0 6.4e-32 110.8 24.0 2.1 1 1 1 2 2 2 1 UbiA prenyltransferase family Spore_YtrH PF14034.6 KXX76054.1 - 0.068 13.3 1.4 1.5 9.0 0.0 2.9 2 0 0 2 2 2 0 Sporulation protein YtrH FAD_binding_4 PF01565.23 KXX76055.1 - 4.7e-28 97.7 1.2 9.6e-28 96.7 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX76055.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like UCR_Fe-S_N PF10399.9 KXX76055.1 - 1.8 8.0 4.3 6 6.3 4.3 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PP-binding PF00550.25 KXX76057.1 - 3.5e-12 46.5 0.1 4.6e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXX76057.1 - 4.1e-05 23.7 0.2 5.2e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.24 KXX76058.1 - 9.9e-11 41.3 8.3 1.8e-05 24.5 2.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXX76058.1 - 2e-10 40.2 11.9 2.5e-05 23.9 3.7 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXX76058.1 - 5.8e-10 38.9 17.4 8.7e-05 22.4 4.2 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KXX76058.1 - 1.1e-08 35.7 6.3 0.00012 22.7 0.3 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KXX76058.1 - 6e-06 26.5 1.2 1.2e-05 25.4 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXX76058.1 - 0.051 14.1 18.2 0.87 10.2 6.4 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Fer4 PF00037.27 KXX76060.1 - 4.3e-14 51.6 16.4 5.9e-08 32.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXX76060.1 - 5.7e-13 49.2 10.7 8.9e-13 48.6 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXX76060.1 - 7.3e-11 42.8 6.9 7.6e-05 23.6 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KXX76060.1 - 3.9e-10 39.7 4.7 7.5e-05 22.8 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXX76060.1 - 3.7e-09 36.5 21.0 8.2e-07 29.0 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXX76060.1 - 2.1e-08 34.2 10.1 4.2e-08 33.2 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXX76060.1 - 3.5e-07 30.6 19.5 9.3e-05 22.8 11.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXX76060.1 - 7.1e-07 29.0 16.9 0.00021 21.2 5.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KXX76060.1 - 9.5e-07 28.6 12.2 0.0028 17.6 3.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KXX76060.1 - 2.1e-05 24.6 11.6 0.00067 20.0 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXX76060.1 - 0.00012 22.5 12.0 0.022 15.3 13.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KXX76060.1 - 0.0061 16.8 5.5 0.76 10.1 0.5 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KXX76060.1 - 0.033 14.4 9.3 0.51 10.6 1.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KXX76060.1 - 0.046 13.9 4.9 0.24 11.6 0.3 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 KXX76060.1 - 0.081 13.5 14.8 0.82 10.3 4.0 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KXX76060.1 - 0.089 13.8 16.6 0.41 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain EPF PF17181.4 KXX76060.1 - 0.42 10.6 5.8 0.18 11.9 0.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 KXX76060.1 - 0.46 11.3 11.9 3.4 8.6 2.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Dynamin_N PF00350.23 KXX76061.1 - 2.3e-23 83.1 0.1 1.9e-22 80.1 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KXX76061.1 - 2.3e-13 50.0 0.1 2e-12 46.9 0.0 2.5 2 1 1 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 KXX76061.1 - 1.5e-05 25.1 0.0 0.00016 21.8 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 KXX76061.1 - 0.00045 20.3 0.8 0.00045 20.3 0.8 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Roc PF08477.13 KXX76061.1 - 0.0056 16.9 0.0 5.3 7.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 KXX76061.1 - 0.046 13.5 0.5 3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXX76061.1 - 0.046 14.1 1.6 0.24 11.7 0.0 3.0 2 1 1 3 3 3 0 AAA ATPase domain bPH_6 PF10756.9 KXX76061.1 - 0.09 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain AAA_28 PF13521.6 KXX76061.1 - 0.12 12.6 0.1 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXX76061.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain VBS PF08913.10 KXX76061.1 - 0.16 12.4 0.0 0.48 10.9 0.0 1.8 1 0 0 1 1 1 0 Vinculin Binding Site Peptidase_S64 PF08192.11 KXX76062.1 - 0.28 9.6 0.0 0.53 8.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 AMP-binding PF00501.28 KXX76066.1 - 4.3e-21 75.0 0.0 4.5e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Gly_transf_sug PF04488.15 KXX76067.1 - 3e-14 53.4 0.0 6.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.28 KXX76069.1 - 1.6e-52 178.6 0.0 1.9e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX76069.1 - 9.2e-22 77.8 0.2 2.7e-21 76.3 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain tRNA-synt_1e PF01406.19 KXX76070.1 - 1.9e-111 372.3 0.2 3.1e-111 371.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 KXX76070.1 - 0.00018 21.9 0.0 0.00075 19.9 0.0 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 KXX76070.1 - 0.00099 18.0 0.1 0.69 8.6 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) adh_short PF00106.25 KXX76071.1 - 1.3e-46 158.6 4.2 1.6e-46 158.2 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76071.1 - 1.2e-44 152.6 3.5 1.4e-44 152.4 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76071.1 - 7.3e-10 39.0 1.0 1.4e-09 38.1 1.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX76071.1 - 0.00047 19.7 0.1 0.00084 18.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX76071.1 - 0.00062 19.3 0.0 0.0016 17.9 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXX76071.1 - 0.0014 18.5 0.5 0.0024 17.8 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KXX76071.1 - 0.0044 16.2 0.2 0.0064 15.6 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXX76071.1 - 0.0091 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXX76071.1 - 0.014 14.4 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KXX76071.1 - 0.023 15.3 0.4 0.048 14.2 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 KXX76071.1 - 0.025 14.4 1.6 0.05 13.4 1.6 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 KXX76071.1 - 0.031 13.6 0.1 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KXX76071.1 - 0.033 13.6 0.2 0.068 12.5 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 KXX76071.1 - 0.046 13.3 0.8 0.079 12.5 0.8 1.4 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 KXX76071.1 - 0.051 13.8 0.2 0.086 13.1 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain Lipocalin_2 PF08212.12 KXX76072.1 - 7.5e-15 55.1 0.0 8.4e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 KXX76072.1 - 0.00013 22.2 0.0 0.0002 21.6 0.0 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Polysacc_lyase PF14099.6 KXX76073.1 - 3e-45 154.7 5.4 3.7e-45 154.4 5.4 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF4781 PF16013.5 KXX76075.1 - 0.32 9.7 4.7 0.44 9.3 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Nuc_sug_transp PF04142.15 KXX76076.1 - 3.6e-100 335.2 13.0 6.3e-100 334.4 13.0 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXX76076.1 - 1.2e-06 28.0 14.2 4e-06 26.2 13.7 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXX76076.1 - 4.8e-05 23.6 29.8 0.0014 18.8 7.9 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KXX76076.1 - 0.0018 17.7 17.1 0.04 13.3 8.0 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family DCA16 PF15349.6 KXX76076.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 NDUFA12 PF05071.16 KXX76077.1 - 2.1e-29 102.2 1.2 3e-29 101.7 1.2 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4188 PF13826.6 KXX76077.1 - 0.079 13.3 0.7 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) PLDc_2 PF13091.6 KXX76078.1 - 3.6e-16 59.3 0.0 8.6e-08 32.1 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXX76078.1 - 4.9e-08 32.8 1.9 0.0066 16.6 0.3 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif CENP-K PF11802.8 KXX76078.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Centromere-associated protein K Virulence_fact PF13769.6 KXX76078.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Virulence factor HAUS-augmin3 PF14932.6 KXX76079.1 - 4.7e-05 23.1 7.5 4.7e-05 23.1 7.5 2.9 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 STAT_alpha PF01017.20 KXX76079.1 - 0.012 15.5 4.8 0.012 15.5 4.8 2.7 3 0 0 3 3 3 0 STAT protein, all-alpha domain Mis14 PF08641.12 KXX76079.1 - 0.018 15.4 2.7 0.018 15.4 2.7 3.3 3 1 1 4 4 4 0 Kinetochore protein Mis14 like V_ATPase_I PF01496.19 KXX76079.1 - 0.34 8.8 2.9 0.55 8.1 2.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 KXX76079.1 - 0.73 10.1 4.4 9.7 6.5 0.2 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF418 PF04235.12 KXX76081.1 - 1.2 9.1 9.6 0.55 10.1 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF418) BCHF PF07284.11 KXX76081.1 - 3 7.9 7.8 4 7.5 7.8 1.2 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) GMC_oxred_N PF00732.19 KXX76082.1 - 6.8e-67 225.9 0.0 8.8e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX76082.1 - 1.3e-27 97.1 0.0 2.5e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXX76082.1 - 0.00026 20.7 0.2 0.0034 17.0 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX76082.1 - 0.0058 15.8 0.1 2.7 7.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXX76082.1 - 0.007 16.6 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX76082.1 - 0.0098 15.0 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXX76082.1 - 0.037 13.3 1.4 0.11 11.7 0.1 2.2 2 0 0 2 2 2 0 Thi4 family RecC_C PF17946.1 KXX76084.1 - 0.068 13.0 0.7 0.11 12.3 0.7 1.2 1 0 0 1 1 1 0 RecC C-terminal domain Mito_carr PF00153.27 KXX76085.1 - 1.3e-67 223.8 1.5 9.3e-22 76.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_3 PF13302.7 KXX76086.1 - 3.5e-30 105.5 0.0 4.2e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXX76086.1 - 5.3e-06 26.6 0.0 7.6e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX76086.1 - 1.8e-05 24.9 0.0 2.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KXX76086.1 - 4.6e-05 23.1 0.1 0.00027 20.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Serine_rich PF08824.10 KXX76087.1 - 0.026 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain F-box-like PF12937.7 KXX76088.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.8 1 1 0 1 1 1 0 F-box-like PNTB PF02233.16 KXX76089.1 - 5.5e-160 533.3 28.7 5.5e-160 533.3 28.7 3.1 2 1 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KXX76089.1 - 1.3e-74 250.1 0.3 3.8e-74 248.6 0.3 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KXX76089.1 - 4e-47 159.9 1.4 5.3e-47 159.5 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KXX76089.1 - 1e-29 102.8 3.0 1e-29 102.8 3.0 5.7 4 2 0 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KXX76089.1 - 0.00086 18.7 0.1 0.42 10.0 0.1 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KXX76089.1 - 0.0038 17.2 1.7 0.0087 16.0 0.2 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KXX76089.1 - 0.0098 15.2 0.2 0.024 13.9 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.14 KXX76089.1 - 0.038 13.4 0.2 0.066 12.6 0.2 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) NAD_binding_8 PF13450.6 KXX76089.1 - 0.12 12.6 2.8 1.1 9.6 2.7 2.8 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FSH1 PF03959.13 KXX76090.1 - 2.2e-30 105.9 0.0 2.5e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXX76090.1 - 0.00069 20.3 5.9 0.0026 18.4 4.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF5404 PF17397.2 KXX76091.1 - 0.044 13.9 0.6 0.044 13.9 0.6 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5404) Acyl_transf_3 PF01757.22 KXX76092.1 - 2.5e-21 76.1 20.6 6.4e-21 74.8 20.2 1.9 1 1 0 1 1 1 1 Acyltransferase family Nbs1_C PF08599.10 KXX76093.1 - 0.54 10.4 2.5 1 9.5 2.5 1.4 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 zf-RING_2 PF13639.6 KXX76094.1 - 1.2e-05 25.6 6.1 4.1e-05 23.8 6.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX76094.1 - 6.4e-05 22.8 3.1 7.9e-05 22.5 1.6 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX76094.1 - 0.00011 22.4 2.9 0.0004 20.6 3.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXX76094.1 - 0.00012 21.7 0.2 0.00046 19.9 0.2 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXX76094.1 - 0.00022 21.2 6.5 0.0037 17.3 1.1 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXX76094.1 - 0.00022 21.0 3.5 0.00022 21.0 3.5 3.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX76094.1 - 0.00044 20.1 0.6 0.00044 20.1 0.6 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX76094.1 - 0.00087 19.2 3.4 0.00087 19.2 3.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXX76094.1 - 0.018 14.9 4.1 0.054 13.4 4.1 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXX76094.1 - 0.053 13.7 0.8 0.053 13.7 0.8 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXX76094.1 - 0.12 12.4 0.6 0.23 11.5 0.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 KXX76094.1 - 0.23 11.4 2.1 0.35 10.8 2.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Zn_ribbon_17 PF17120.5 KXX76094.1 - 6.7 6.4 8.5 1 9.0 2.5 2.5 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KXX76095.1 - 1.3e-42 142.9 20.4 1.6e-06 28.8 0.3 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KXX76095.1 - 7.6e-11 41.7 0.1 7.3e-10 38.6 0.3 2.6 3 0 0 3 3 3 1 F-box-like ANAPC4_WD40 PF12894.7 KXX76095.1 - 5.1e-10 39.5 1.5 0.056 13.8 0.0 5.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KXX76095.1 - 2.4e-08 33.6 0.1 1.1e-07 31.5 0.0 2.2 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.8 KXX76095.1 - 5.4e-07 28.6 1.6 0.41 9.2 0.0 4.1 3 1 1 4 4 4 4 Nucleoporin Nup120/160 F-box_4 PF15966.5 KXX76095.1 - 0.00061 19.7 0.0 0.003 17.4 0.0 2.2 1 0 0 1 1 1 1 F-box DASH_Dad4 PF08650.10 KXX76096.1 - 3e-32 110.4 7.4 3.3e-32 110.3 7.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 HOK_GEF PF01848.16 KXX76096.1 - 0.04 13.3 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Hok/gef family Biotin_carb_C PF02785.19 KXX76096.1 - 0.05 13.7 0.2 0.054 13.6 0.2 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain GM_CSF PF01109.17 KXX76096.1 - 0.086 13.0 0.5 0.099 12.8 0.5 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor FA_hydroxylase PF04116.13 KXX76097.1 - 9.7e-27 93.9 15.1 9.7e-27 93.9 15.1 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.19 KXX76098.1 - 9.9e-23 80.1 0.2 1.3e-22 79.8 0.2 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase SUIM_assoc PF16619.5 KXX76098.1 - 0.013 15.5 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 bZIP_1 PF00170.21 KXX76099.1 - 6.9e-09 35.7 7.3 2.4e-08 33.9 7.3 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXX76099.1 - 0.42 10.7 9.1 19 5.4 9.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Actin PF00022.19 KXX76100.1 - 3.1e-55 187.4 0.0 1.7e-32 112.6 0.0 2.3 2 1 0 2 2 2 2 Actin Ras PF00071.22 KXX76101.1 - 5.5e-65 217.9 0.0 7.2e-65 217.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX76101.1 - 7.5e-34 116.5 0.0 1.4e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX76101.1 - 4.5e-13 49.0 0.0 5.5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXX76101.1 - 9.1e-06 25.3 0.0 2.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXX76101.1 - 0.00027 20.4 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXX76101.1 - 0.0013 18.6 0.2 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXX76101.1 - 0.0028 17.7 0.0 0.0062 16.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX76101.1 - 0.016 14.7 0.0 0.08 12.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KXX76101.1 - 0.029 13.8 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KXX76101.1 - 0.13 12.5 0.1 0.49 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.10 KXX76102.1 - 3.7e-109 364.4 0.1 6.3e-109 363.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TAP42 PF04177.12 KXX76104.1 - 1.1e-111 373.0 0.1 1.2e-111 372.8 0.1 1.0 1 0 0 1 1 1 1 TAP42-like family KBP_C PF12309.8 KXX76104.1 - 0.013 15.0 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Ribonuclease_3 PF00636.26 KXX76106.1 - 1.9e-38 131.3 0.0 1.3e-17 64.4 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KXX76106.1 - 3.4e-22 78.4 0.0 4.7e-21 74.8 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KXX76106.1 - 6.6e-21 74.8 0.0 7.4e-09 35.8 0.0 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.31 KXX76106.1 - 1.1e-13 51.4 0.1 2.8e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX76106.1 - 2.6e-12 47.1 0.0 5.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXX76106.1 - 1.8e-10 40.8 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXX76106.1 - 0.049 13.9 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 KXX76106.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PNP_phzG_C PF10590.9 KXX76107.1 - 9.5e-22 76.8 1.8 1.5e-20 72.9 2.8 2.3 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KXX76107.1 - 4.1e-12 46.1 0.0 2.4e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KXX76107.1 - 0.12 12.9 0.0 0.3 11.7 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF3833 PF12915.7 KXX76107.1 - 0.2 11.2 0.5 12 5.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3833) adh_short PF00106.25 KXX76108.1 - 1.8e-17 63.4 0.3 4.5e-16 58.9 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76108.1 - 1.5e-07 31.2 0.0 6.1e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76108.1 - 8.4e-07 29.1 0.7 2.3e-06 27.6 0.0 1.9 2 1 1 3 3 3 1 KR domain Epimerase PF01370.21 KXX76108.1 - 2.3e-06 27.2 0.0 4.7e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX76108.1 - 0.00028 20.4 4.2 0.51 9.7 0.0 2.9 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase E1-N PF14463.6 KXX76108.1 - 0.0039 17.0 0.1 0.011 15.6 0.0 1.8 1 1 1 2 2 2 1 E1 N-terminal domain Ldh_1_N PF00056.23 KXX76108.1 - 0.13 12.3 0.0 22 5.1 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 KXX76108.1 - 0.14 11.8 0.1 3.8 7.1 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Sec63 PF02889.16 KXX76110.1 - 4.3e-133 442.3 0.0 2.6e-80 269.3 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXX76110.1 - 3.9e-50 170.1 0.0 1.4e-26 93.4 0.3 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KXX76110.1 - 3.7e-22 79.1 0.0 2.4e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXX76110.1 - 4.9e-16 59.1 0.2 9.5e-07 29.2 0.0 4.8 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXX76110.1 - 4.4e-07 29.8 0.2 0.02 14.6 0.3 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KXX76110.1 - 2.4e-06 27.9 0.8 0.23 11.8 0.2 3.7 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXX76110.1 - 1.8e-05 25.1 0.3 0.0026 18.1 0.5 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXX76110.1 - 0.00057 20.3 0.2 2.6 8.5 0.0 4.5 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 KXX76110.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain TniB PF05621.11 KXX76110.1 - 0.093 12.1 0.2 19 4.6 0.0 3.8 4 0 0 4 4 4 0 Bacterial TniB protein G-patch PF01585.23 KXX76111.1 - 1.1e-07 31.6 0.1 1.9e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 G-patch domain Peptidase_C12 PF01088.21 KXX76112.1 - 5.4e-32 111.2 0.0 2.2e-16 60.3 0.0 2.1 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF4632 PF15451.6 KXX76113.1 - 0.12 12.5 1.5 0.76 9.9 1.5 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Synaptobrevin PF00957.21 KXX76114.1 - 1.3e-30 105.0 0.0 1.9e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXX76114.1 - 9.4e-27 92.9 0.1 1.6e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Cation_efflux PF01545.21 KXX76114.1 - 0.019 14.7 0.9 0.062 13.0 0.1 2.0 2 0 0 2 2 2 0 Cation efflux family SUV3_C PF12513.8 KXX76115.1 - 6.7e-18 64.3 2.5 1.3e-17 63.4 1.0 2.3 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KXX76115.1 - 2.5e-11 43.3 0.1 5.5e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 KXX76115.1 - 4.8e-09 36.6 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.18 KXX76115.1 - 0.035 14.0 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase adh_short_C2 PF13561.6 KXX76116.1 - 9e-53 179.2 0.1 1.1e-52 178.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX76116.1 - 3.3e-43 147.4 0.0 4e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX76116.1 - 3.9e-17 62.8 0.3 6.6e-17 62.0 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX76116.1 - 0.00054 19.5 0.0 0.00073 19.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX76116.1 - 0.028 13.8 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXX76116.1 - 0.04 13.0 0.3 0.059 12.5 0.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain AlaDh_PNT_C PF01262.21 KXX76116.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Proteasome PF00227.26 KXX76117.1 - 2.2e-25 89.3 0.0 1.3e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit DUF2567 PF10821.8 KXX76117.1 - 0.04 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) FMN_dh PF01070.18 KXX76118.1 - 6.2e-104 347.8 0.0 7.7e-104 347.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXX76118.1 - 4.9e-20 71.5 0.0 2.3e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KXX76118.1 - 3e-06 26.5 0.0 0.00012 21.2 0.0 2.8 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXX76118.1 - 4.5e-06 26.0 0.0 7.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXX76118.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 KXX76118.1 - 0.032 13.6 0.2 0.052 12.9 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 KXX76118.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ATP11 PF06644.11 KXX76118.1 - 0.12 12.1 0.1 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 ATP11 protein SNF2_N PF00176.23 KXX76119.1 - 6.3e-35 120.5 0.0 8.2e-33 113.6 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX76119.1 - 1.2e-08 35.3 0.1 2.2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX76119.1 - 0.18 11.8 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit LRR_8 PF13855.6 KXX76120.1 - 0.0049 16.6 0.9 0.015 15.1 0.9 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXX76120.1 - 0.043 14.3 1.5 3.5 8.2 1.0 3.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) HCNGP PF07818.13 KXX76121.1 - 6e-26 90.9 0.0 5.2e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 HCNGP-like protein SIS PF01380.22 KXX76122.1 - 2.4e-61 205.3 0.2 6.6e-32 110.1 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KXX76122.1 - 6.8e-18 65.2 0.0 1.4e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXX76122.1 - 5.6e-10 39.2 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXX76122.1 - 0.0028 16.6 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KXX76122.1 - 0.07 13.2 0.0 1.4 8.9 0.0 2.5 2 1 0 2 2 2 0 SIS domain AAA PF00004.29 KXX76123.1 - 2.3e-42 144.6 0.0 4.2e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXX76123.1 - 2.1e-11 43.6 0.1 8.5e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXX76123.1 - 8.6e-10 38.3 0.1 2e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXX76123.1 - 3.2e-07 30.9 0.1 0.00016 22.1 0.1 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXX76123.1 - 1.1e-05 25.5 0.1 0.00012 22.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXX76123.1 - 1.3e-05 25.4 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXX76123.1 - 2.1e-05 24.3 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KXX76123.1 - 0.001 18.3 0.0 0.0024 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXX76123.1 - 0.001 19.3 0.1 0.015 15.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KXX76123.1 - 0.0015 19.1 0.0 0.0079 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXX76123.1 - 0.0036 16.8 0.0 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KXX76123.1 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 KXX76123.1 - 0.0079 15.8 0.0 0.025 14.2 0.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 KXX76123.1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KXX76123.1 - 0.01 15.7 0.2 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXX76123.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXX76123.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXX76123.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KXX76123.1 - 0.014 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Fungal_trans_2 PF11951.8 KXX76123.1 - 0.017 14.0 0.1 0.017 14.0 0.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain AAA_14 PF13173.6 KXX76123.1 - 0.024 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXX76123.1 - 0.032 13.9 0.0 0.082 12.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KXX76123.1 - 0.034 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXX76123.1 - 0.056 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 KXX76123.1 - 0.06 13.7 2.0 0.15 12.5 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_30 PF13604.6 KXX76123.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXX76123.1 - 0.11 11.8 0.2 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 KXX76123.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 KXX76123.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KXX76123.1 - 0.19 11.9 0.4 0.44 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF3712 PF12505.8 KXX76124.1 - 4.6e-28 98.0 0.3 4.6e-28 98.0 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Lactamase_B_2 PF12706.7 KXX76125.1 - 1.2e-13 51.0 0.2 2.2e-13 50.2 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXX76125.1 - 6.2e-13 49.0 0.0 8.3e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Protoglobin PF11563.8 KXX76126.1 - 7.4e-61 204.7 0.1 8.8e-61 204.4 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Gln-synt_C PF00120.24 KXX76127.1 - 7.2e-13 48.2 0.0 1e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXX76127.1 - 8.6e-12 44.6 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Fungal_trans_2 PF11951.8 KXX76128.1 - 6.8e-06 25.1 0.1 8.6e-06 24.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX76128.1 - 1.9e-05 24.7 7.5 4e-05 23.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KXX76129.1 - 1.8e-36 125.7 6.0 2.6e-36 125.2 6.0 1.2 1 0 0 1 1 1 1 RTA1 like protein TMEM107 PF14995.6 KXX76129.1 - 0.33 11.4 0.0 0.33 11.4 0.0 3.3 3 0 0 3 3 3 0 Transmembrane protein Epimerase PF01370.21 KXX76130.1 - 6.4e-20 71.6 0.0 9.5e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX76130.1 - 2e-18 66.9 0.5 4.6e-12 46.0 0.1 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXX76130.1 - 1.7e-10 40.5 1.2 5.2e-07 29.1 0.1 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXX76130.1 - 2.4e-10 40.0 0.0 2.6e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXX76130.1 - 8.6e-06 25.0 0.0 4.1e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXX76130.1 - 5.8e-05 22.4 0.4 0.00034 19.9 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KXX76130.1 - 0.095 12.2 0.1 0.71 9.3 0.0 2.3 2 1 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 KXX76130.1 - 0.1 12.5 0.3 10 6.0 0.0 2.1 2 0 0 2 2 2 0 KR domain HTH_21 PF13276.6 KXX76131.1 - 0.024 14.8 7.3 0.52 10.5 7.3 2.1 1 1 0 1 1 1 0 HTH-like domain HSCB_C PF07743.13 KXX76132.1 - 2.7e-21 75.9 3.0 2.7e-21 75.9 3.0 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KXX76132.1 - 0.0088 16.2 0.1 0.17 12.1 0.1 2.4 1 1 0 1 1 1 1 DnaJ domain DBP PF12361.8 KXX76132.1 - 0.24 11.2 0.2 0.24 11.2 0.2 1.5 2 0 0 2 2 2 0 Duffy-antigen binding protein PCI PF01399.27 KXX76133.1 - 2.3e-11 44.1 0.0 2.1e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 KXX76133.1 - 9e-06 25.5 0.3 5.2e-05 23.0 0.1 2.1 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TetR_C_11 PF16859.5 KXX76133.1 - 0.018 15.3 3.1 0.018 15.3 3.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SAM_Exu PF18609.1 KXX76133.1 - 0.095 12.8 0.0 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 Exuperantia SAM-like domain T2SSF PF00482.23 KXX76133.1 - 0.23 11.4 2.2 2.3 8.2 0.3 3.3 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F Lipase_GDSL_2 PF13472.6 KXX76134.1 - 2.9e-19 70.1 0.0 3.6e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX76134.1 - 9.3e-09 35.5 0.0 1.7e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cadherin_pro PF08758.11 KXX76136.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Cadherin prodomain like HAT_KAT11 PF08214.11 KXX76137.1 - 3.1e-90 303.0 0.0 3.9e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein SET PF00856.28 KXX76138.1 - 7.9e-19 68.7 0.0 1.8e-18 67.5 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KXX76138.1 - 3.9e-07 30.8 0.4 1.3e-06 29.1 0.1 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 KXX76141.1 - 1.2e-13 51.8 0.0 4.5e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 SET domain DIX PF00778.17 KXX76141.1 - 0.19 11.6 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 DIX domain MFS_1 PF07690.16 KXX76143.1 - 2.8e-35 121.9 27.6 3.4e-33 115.0 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX76143.1 - 2.4e-09 36.6 24.8 5.6e-09 35.4 24.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 KXX76143.1 - 0.0047 16.7 3.9 0.046 13.5 0.0 3.2 3 1 0 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HTH_38 PF13936.6 KXX76143.1 - 0.092 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain YfhO PF09586.10 KXX76143.1 - 0.11 10.7 2.7 0.14 10.3 1.3 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO LapA_dom PF06305.11 KXX76143.1 - 3.4 7.6 7.0 4.1 7.3 0.0 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SRP54 PF00448.22 KXX76144.1 - 8.9e-76 253.9 1.7 4.8e-75 251.5 0.5 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KXX76144.1 - 1.5e-31 109.0 6.4 1.5e-31 109.0 6.4 3.5 3 1 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 KXX76144.1 - 2e-14 53.5 0.2 5.4e-14 52.2 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KXX76144.1 - 7.6e-07 28.9 0.6 7.9e-06 25.6 0.6 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXX76144.1 - 9.9e-07 29.0 0.0 2.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXX76144.1 - 0.0001 22.7 0.6 0.00036 21.0 0.1 2.2 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXX76144.1 - 0.00023 21.6 0.0 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KXX76144.1 - 0.00046 19.9 0.1 0.0023 17.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 KXX76144.1 - 0.00098 18.2 3.2 0.0021 17.1 0.8 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KXX76144.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KXX76144.1 - 0.0018 17.6 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 KXX76144.1 - 0.0022 18.0 0.0 0.0067 16.5 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KXX76144.1 - 0.0027 17.4 0.2 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase MMR_HSR1 PF01926.23 KXX76144.1 - 0.0045 17.1 0.3 0.095 12.8 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXX76144.1 - 0.005 16.3 1.0 2.3 7.6 0.7 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KXX76144.1 - 0.0057 17.2 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXX76144.1 - 0.0075 16.3 0.2 0.033 14.2 0.2 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXX76144.1 - 0.0094 16.2 0.0 0.029 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KXX76144.1 - 0.011 15.5 0.1 0.041 13.7 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KXX76144.1 - 0.014 15.8 0.2 0.079 13.4 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXX76144.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KXX76144.1 - 0.016 15.1 0.1 0.042 13.8 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 KXX76144.1 - 0.016 15.6 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KXX76144.1 - 0.045 13.1 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 KXX76144.1 - 0.076 12.5 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 1 0 ADP-ribosylation factor family NTPase_1 PF03266.15 KXX76144.1 - 0.078 12.9 0.6 0.61 10.0 0.6 2.2 1 1 0 1 1 1 0 NTPase Torsin PF06309.11 KXX76144.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.7 1 1 0 1 1 1 0 Torsin SKA2 PF16740.5 KXX76144.1 - 0.15 11.8 4.1 6.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 ABC_tran PF00005.27 KXX76144.1 - 0.15 12.5 1.1 0.47 11.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter ABM PF03992.16 KXX76145.1 - 0.00034 20.7 0.0 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase GSDH PF07995.11 KXX76146.1 - 3.1e-07 30.0 0.6 8.6e-07 28.6 0.2 1.8 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SBP_bac_3 PF00497.20 KXX76147.1 - 9.8e-06 25.2 0.0 3.7e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 KXX76147.1 - 2.6e-05 23.9 0.0 0.00042 20.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KXX76147.1 - 0.014 15.3 0.0 0.12 12.2 0.0 2.3 1 1 0 1 1 1 0 NMT1/THI5 like DUF3834 PF12916.7 KXX76147.1 - 0.094 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) T3SS_TC PF06511.11 KXX76147.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Type III secretion systems tip complex components NMT1_2 PF13379.6 KXX76147.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family Ribonucleas_3_3 PF14622.6 KXX76148.1 - 1.9e-32 112.1 0.0 5.2e-32 110.7 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXX76148.1 - 0.0021 18.7 0.0 0.0056 17.3 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain DUF1997 PF09366.10 KXX76149.1 - 0.92 9.6 3.4 2.1 8.5 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1997) Peroxidase_2 PF01328.17 KXX76150.1 - 1.3e-44 153.0 0.0 1.8e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Aldo_ket_red PF00248.21 KXX76151.1 - 7.6e-48 163.2 0.2 4e-47 160.8 0.0 1.8 1 1 1 2 2 2 2 Aldo/keto reductase family MFS_1 PF07690.16 KXX76152.1 - 2.3e-27 95.9 44.5 2.4e-26 92.5 44.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX76152.1 - 2.7e-16 59.1 12.2 3.4e-16 58.8 12.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CHAP PF05257.16 KXX76153.1 - 3.8e-13 49.8 3.8 3.8e-13 49.8 3.8 2.0 2 0 0 2 2 2 1 CHAP domain SH3_3 PF08239.11 KXX76153.1 - 5.6e-05 23.3 0.2 0.00013 22.2 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Phage_lysozyme PF00959.19 KXX76154.1 - 2.8e-12 47.0 0.0 4.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.11 KXX76154.1 - 3.4e-05 24.0 0.9 7.8e-05 22.9 0.4 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.13 KXX76154.1 - 0.023 14.5 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain Sugar_tr PF00083.24 KXX76155.1 - 1.2e-93 314.5 27.6 1.8e-93 313.9 27.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX76155.1 - 2.2e-28 99.2 58.4 6.9e-27 94.3 33.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX76155.1 - 1.8e-06 26.7 1.0 1.8e-06 26.7 1.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KXX76155.1 - 1.2 9.4 9.8 0.57 10.5 2.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) bMG10 PF17973.1 KXX76156.1 - 0.019 15.1 0.1 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain Fungal_trans PF04082.18 KXX76157.1 - 1.3e-16 60.4 0.0 2.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX76157.1 - 4.1e-05 23.6 9.0 7.8e-05 22.7 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1631 PF07793.11 KXX76157.1 - 0.23 9.9 6.2 0.021 13.3 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) ANAPC_CDC26 PF10471.9 KXX76157.1 - 6.6 7.6 9.8 0.86 10.5 0.9 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Glyco_hydro_115 PF15979.5 KXX76158.1 - 1.7e-130 435.4 0.8 2.3e-130 435.0 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXX76158.1 - 1.2e-34 119.6 0.0 2.4e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Pkinase PF00069.25 KXX76160.1 - 2.4e-43 148.4 0.0 9.5e-43 146.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76160.1 - 2e-30 105.9 0.0 3e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX76160.1 - 0.00099 18.0 0.1 0.032 13.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXX76160.1 - 0.0097 15.3 0.0 0.027 13.8 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 KXX76160.1 - 0.011 15.8 7.2 0.015 15.3 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.6 KXX76160.1 - 0.031 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Menin PF05053.13 KXX76160.1 - 1.2 7.4 5.5 1.8 6.8 5.5 1.2 1 0 0 1 1 1 0 Menin AF-4 PF05110.13 KXX76160.1 - 1.4 7.0 14.6 2 6.4 14.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PAP1 PF08601.10 KXX76160.1 - 2.1 8.0 15.4 3.3 7.4 15.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 GMC_oxred_C PF05199.13 KXX76161.1 - 1.9e-35 122.5 0.0 3.3e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXX76161.1 - 3.1e-23 82.6 0.0 5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Sulfotransfer_4 PF17784.1 KXX76163.1 - 1.6e-55 188.2 0.0 1.9e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXX76163.1 - 0.0005 20.5 0.0 0.0008 19.9 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family SIS PF01380.22 KXX76163.1 - 0.043 13.7 0.0 0.25 11.2 0.0 2.1 1 1 0 1 1 1 0 SIS domain GMC_oxred_N PF00732.19 KXX76164.1 - 2e-17 63.5 0.1 3.7e-17 62.6 0.1 1.4 1 1 0 1 1 1 1 GMC oxidoreductase HET PF06985.11 KXX76165.1 - 6.6e-22 78.4 1.4 6.7e-21 75.2 0.3 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) COesterase PF00135.28 KXX76166.1 - 6.6e-79 266.1 0.0 2e-66 224.9 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX76166.1 - 4.1e-09 36.6 0.0 7.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX76166.1 - 0.048 12.9 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXX76166.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DEC-1_C PF04626.13 KXX76166.1 - 0.092 13.1 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Dec-1 protein, C terminal region adh_short PF00106.25 KXX76167.1 - 9.5e-08 31.7 1.5 3.3e-06 26.7 0.5 2.2 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76167.1 - 0.0038 16.8 0.6 0.0069 16.0 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXX76167.1 - 0.008 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KXX76167.1 - 0.017 14.5 0.0 1.2 8.5 0.0 2.2 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KXX76167.1 - 0.031 13.8 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 KXX76167.1 - 0.036 13.5 0.1 0.07 12.6 0.1 1.5 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Dodecin PF07311.12 KXX76167.1 - 0.042 14.1 0.1 0.45 10.8 0.0 2.3 3 0 0 3 3 3 0 Dodecin ApbA PF02558.16 KXX76167.1 - 0.056 13.1 0.3 0.095 12.3 0.3 1.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KXX76167.1 - 0.074 13.6 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KXX76167.1 - 0.093 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Rossmann-like domain Lig_chan PF00060.26 KXX76168.1 - 4.7 7.0 4.9 5.2 6.9 0.7 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel Yippee-Mis18 PF03226.14 KXX76169.1 - 7.2e-17 61.5 0.3 8.2e-17 61.3 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 KXX76169.1 - 0.0079 16.5 1.1 0.077 13.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.8 KXX76169.1 - 0.015 15.6 0.5 0.02 15.1 0.5 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I HNH_5 PF14279.6 KXX76169.1 - 0.034 14.0 0.3 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Ferric_reduct PF01794.19 KXX76170.1 - 2.1e-22 79.6 12.2 2.1e-22 79.6 12.2 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXX76170.1 - 2.3e-20 73.3 0.0 1.2e-17 64.5 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXX76170.1 - 2.3e-12 47.0 0.0 2.6e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain DUF2985 PF11204.8 KXX76171.1 - 3.8e-36 123.1 3.2 3.8e-36 123.1 3.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) Nuc_sug_transp PF04142.15 KXX76172.1 - 2.8e-07 30.0 0.0 5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KXX76172.1 - 4e-06 27.1 28.3 0.00039 20.6 3.4 2.9 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 KXX76172.1 - 0.00051 19.5 0.4 0.00051 19.5 0.4 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family Hol_Tox PF16935.5 KXX76172.1 - 0.008 16.2 0.1 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Putative Holin-like Toxin (Hol-Tox) PDR_assoc PF08370.11 KXX76172.1 - 0.067 12.9 6.7 1.1 9.1 0.2 3.3 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DUF423 PF04241.15 KXX76172.1 - 0.17 12.1 7.0 3.4 7.9 2.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF2613 PF11021.8 KXX76172.1 - 0.82 9.8 11.3 0.4 10.8 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Aminotran_3 PF00202.21 KXX76173.1 - 2.1e-76 257.2 0.0 2.5e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Adeno_PX PF05829.12 KXX76173.1 - 0.53 10.2 2.5 1.6 8.7 2.5 1.8 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Trypan_PARP PF05887.11 KXX76174.1 - 0.084 12.9 8.3 0.19 11.7 8.3 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CLU PF13236.6 KXX76175.1 - 5.3e-78 261.9 0.0 9.6e-78 261.0 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KXX76175.1 - 1.5e-51 174.9 0.7 4.5e-51 173.4 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KXX76175.1 - 1.5e-28 98.9 8.0 9.8e-13 48.2 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXX76175.1 - 9.3e-24 82.6 8.8 4.9e-06 26.2 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat CLU_N PF15044.6 KXX76175.1 - 1e-20 73.9 0.0 2.2e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 KXX76175.1 - 1.3e-05 25.2 0.0 3.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 KXX76175.1 - 0.0041 17.2 6.0 0.014 15.5 0.4 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DDHD PF02862.17 KXX76175.1 - 0.051 13.7 0.4 0.17 12.0 0.4 1.9 1 0 0 1 1 1 0 DDHD domain MID_MedPIWI PF18296.1 KXX76175.1 - 0.21 11.3 4.5 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 MID domain of medPIWI TPR_2 PF07719.17 KXX76175.1 - 0.35 11.1 10.8 1.4 9.2 0.4 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NPR3 PF03666.13 KXX76175.1 - 0.89 8.3 8.2 1.8 7.2 8.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 KXX76175.1 - 4.5 7.0 11.3 12 5.7 11.3 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KXX76175.1 - 5.5 5.2 9.4 8.5 4.5 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Forkhead PF00250.18 KXX76176.1 - 2e-33 114.5 0.5 3.3e-33 113.8 0.5 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXX76176.1 - 6.3e-07 29.7 0.0 1.3e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-C2H2 PF00096.26 KXX76177.1 - 1.6e-08 34.5 9.9 0.0055 17.1 2.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX76177.1 - 0.0039 17.6 11.4 0.75 10.3 0.2 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX76177.1 - 0.041 14.7 9.7 0.12 13.3 1.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KXX76177.1 - 1.3 9.4 7.4 0.49 10.7 0.9 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding EnY2 PF10163.9 KXX76179.1 - 0.0024 18.2 0.0 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 Transcription factor e(y)2 AAA PF00004.29 KXX76180.1 - 2.6e-98 325.6 0.0 1.1e-47 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX76180.1 - 4.3e-24 84.0 4.2 9.9e-13 47.7 0.4 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KXX76180.1 - 1.4e-18 66.8 0.4 4.9e-18 65.1 0.4 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KXX76180.1 - 1.2e-14 54.3 0.0 3.1e-06 27.0 0.0 3.3 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXX76180.1 - 8.7e-14 52.0 0.0 2.1e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXX76180.1 - 1.7e-13 51.3 0.0 0.00016 22.1 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KXX76180.1 - 4.2e-12 46.2 0.4 3.4e-06 27.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXX76180.1 - 7.9e-12 45.5 0.0 4.6e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXX76180.1 - 1.5e-09 38.2 0.4 0.027 14.7 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 KXX76180.1 - 2.3e-09 36.9 0.1 0.0011 18.2 0.0 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 KXX76180.1 - 7.4e-08 32.1 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 KXX76180.1 - 1.6e-07 31.9 0.0 0.028 14.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KXX76180.1 - 1.9e-07 30.7 0.3 0.0062 15.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXX76180.1 - 3.1e-07 30.2 4.3 0.21 11.1 0.1 4.8 3 2 1 5 5 5 3 AAA domain IstB_IS21 PF01695.17 KXX76180.1 - 3.2e-07 30.2 0.1 0.02 14.6 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KXX76180.1 - 4.1e-07 30.1 0.0 0.0081 16.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KXX76180.1 - 5.1e-07 30.1 0.0 0.031 14.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 KXX76180.1 - 8.9e-07 28.5 0.3 0.25 10.7 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KXX76180.1 - 1.8e-06 27.6 0.0 0.031 13.8 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 KXX76180.1 - 2.2e-06 27.0 0.0 0.0069 15.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXX76180.1 - 4.3e-06 26.6 0.0 0.082 12.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 KXX76180.1 - 8.7e-06 25.0 0.0 0.05 12.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KXX76180.1 - 1.5e-05 25.3 0.0 0.18 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 KXX76180.1 - 1.7e-05 24.8 0.0 0.09 12.6 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein Sigma54_activat PF00158.26 KXX76180.1 - 1.9e-05 24.4 0.1 0.23 11.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KXX76180.1 - 3.2e-05 24.5 0.0 0.43 11.1 0.0 3.5 2 1 0 2 2 2 2 ABC transporter ResIII PF04851.15 KXX76180.1 - 5.8e-05 23.2 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 KXX76180.1 - 6.1e-05 23.0 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXX76180.1 - 0.00014 21.8 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.6 KXX76180.1 - 0.00019 21.9 0.0 0.59 10.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KXX76180.1 - 0.00021 20.8 0.3 0.68 9.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 KXX76180.1 - 0.00023 21.0 0.0 0.68 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXX76180.1 - 0.00032 20.5 0.2 0.85 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KXX76180.1 - 0.00038 20.3 0.1 1.3 8.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 KXX76180.1 - 0.00051 20.0 0.0 1.9 8.4 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KXX76180.1 - 0.0012 19.2 0.8 5.4 7.3 0.0 3.7 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 KXX76180.1 - 0.0019 17.5 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KXX76180.1 - 0.003 16.8 0.0 1.1 8.4 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activ_2 PF14532.6 KXX76180.1 - 0.0034 17.5 0.0 0.51 10.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KXX76180.1 - 0.0074 16.1 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KXX76180.1 - 0.0079 16.1 1.5 2.5 8.0 0.0 4.0 5 0 0 5 5 3 1 NTPase KAP_NTPase PF07693.14 KXX76180.1 - 0.0093 15.2 0.4 0.86 8.8 0.0 3.3 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.16 KXX76180.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 KXX76180.1 - 0.024 13.9 0.0 7.7 5.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Zot PF05707.12 KXX76180.1 - 0.049 13.3 0.0 2.4 7.8 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 KXX76180.1 - 0.05 13.3 0.0 9.9 5.8 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 KXX76180.1 - 0.052 12.5 0.3 7.5 5.4 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region AFG1_ATPase PF03969.16 KXX76180.1 - 0.054 12.4 0.0 6.7 5.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Vps4_C PF09336.10 KXX76180.1 - 0.084 12.9 0.2 0.87 9.6 0.1 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain UFD1 PF03152.14 KXX76180.1 - 0.091 12.2 0.0 0.43 10.0 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Fungal_trans_2 PF11951.8 KXX76181.1 - 3.7e-08 32.6 0.7 5.8e-08 31.9 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX76181.1 - 0.00014 21.9 3.2 0.00024 21.1 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA_2 PF13911.6 KXX76182.1 - 1.4e-09 38.1 0.0 1.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXX76182.1 - 3.1e-05 23.9 0.0 5.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family ADH_N PF08240.12 KXX76183.1 - 2.3e-30 104.7 3.4 3.8e-30 104.0 3.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX76183.1 - 3.6e-14 52.9 0.0 5.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXX76183.1 - 4.3e-06 26.5 0.1 1.4e-05 24.9 0.1 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KXX76183.1 - 7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXX76183.1 - 0.0046 18.0 0.0 0.0092 17.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXX76183.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sen15 PF09631.10 KXX76184.1 - 3.8e-24 84.9 0.0 6.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Sen15 protein DPPIV_N PF00930.21 KXX76186.1 - 6e-105 350.9 2.5 6e-105 350.9 2.5 1.7 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KXX76186.1 - 9.3e-42 142.9 0.4 1.5e-41 142.2 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXX76186.1 - 0.0014 19.3 2.3 0.0035 18.0 0.9 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXX76186.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 KXX76186.1 - 0.057 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF3809 PF12723.7 KXX76187.1 - 0.17 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) MFS_1 PF07690.16 KXX76189.1 - 5.5e-35 120.9 25.5 7e-35 120.6 25.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX76189.1 - 3.2e-10 39.5 17.2 4.9e-10 38.9 16.5 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter MASE2 PF05230.11 KXX76189.1 - 0.76 9.9 6.7 0.15 12.1 1.2 2.6 2 0 0 2 2 2 0 MASE2 domain Tyrosinase PF00264.20 KXX76190.1 - 4.3e-27 95.8 7.4 4.3e-27 95.8 7.4 3.0 2 2 0 2 2 2 1 Common central domain of tyrosinase CorA PF01544.18 KXX76191.1 - 6.8e-14 51.9 0.1 1.9e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein E1-E2_ATPase PF00122.20 KXX76192.1 - 5.6e-36 123.8 0.3 5.6e-36 123.8 0.3 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXX76192.1 - 3.4e-19 68.7 0.0 7.2e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX76192.1 - 2.2e-18 67.3 0.3 5.5e-18 66.0 0.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX76192.1 - 1.2e-07 31.2 0.2 1.1e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXX76192.1 - 0.0015 18.3 0.3 0.0025 17.6 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KXX76192.1 - 0.0029 17.4 0.1 0.0029 17.4 0.1 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus SPR1 PF15356.6 KXX76192.1 - 0.11 13.0 2.1 4.3 7.9 1.0 2.3 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 TctB PF07331.11 KXX76192.1 - 0.3 11.4 5.9 1.6 9.0 0.8 2.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family WD40 PF00400.32 KXX76193.1 - 1e-31 108.5 14.6 4.3e-06 27.4 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX76193.1 - 3.1e-06 27.4 0.1 0.0076 16.5 0.0 4.3 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KXX76193.1 - 8.4e-06 25.6 0.1 1.8e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KXX76193.1 - 9.1e-05 21.3 0.2 0.87 8.1 0.0 4.0 3 2 1 4 4 4 2 Nucleoporin Nup120/160 F-box PF00646.33 KXX76193.1 - 0.00079 19.2 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cytochrom_D1 PF02239.16 KXX76193.1 - 0.018 13.6 0.0 0.031 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KXX76193.1 - 0.025 13.3 0.1 1.2 7.8 0.0 2.7 3 1 0 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 KXX76193.1 - 0.17 11.2 0.0 15 4.8 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Snapin_Pallidin PF14712.6 KXX76194.1 - 0.029 14.8 0.2 0.074 13.5 0.2 1.7 1 0 0 1 1 1 0 Snapin/Pallidin DUF4081 PF13312.6 KXX76194.1 - 0.15 12.3 0.9 1.3 9.3 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4081) DUF1996 PF09362.10 KXX76195.1 - 1.3e-83 280.6 0.9 1.7e-83 280.2 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 KXX76195.1 - 2.5e-11 43.3 18.6 2.5e-11 43.3 18.6 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain HCO3_cotransp PF00955.21 KXX76196.1 - 1.2e-65 222.3 13.9 1.8e-39 135.9 6.5 2.7 1 1 1 2 2 2 2 HCO3- transporter family ABC_tran PF00005.27 KXX76197.1 - 2.3e-39 135.0 0.0 2.5e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXX76197.1 - 1.1e-25 90.8 11.0 1.7e-25 90.3 11.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KXX76197.1 - 5.7e-11 42.3 1.4 0.0082 15.6 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXX76197.1 - 1.3e-09 38.3 1.3 0.00097 19.0 0.0 3.2 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXX76197.1 - 2.6e-07 30.2 1.8 0.0066 16.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXX76197.1 - 3e-06 27.9 0.3 0.013 16.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXX76197.1 - 1.7e-05 25.1 0.1 0.32 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXX76197.1 - 2.7e-05 23.8 0.1 0.074 12.6 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 KXX76197.1 - 5e-05 23.8 0.1 0.042 14.2 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXX76197.1 - 5.9e-05 23.1 0.4 0.36 10.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXX76197.1 - 0.00027 21.0 1.3 0.035 14.2 0.1 2.3 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KXX76197.1 - 0.00033 20.6 0.4 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KXX76197.1 - 0.00038 19.6 0.1 0.2 10.7 0.0 2.5 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_30 PF13604.6 KXX76197.1 - 0.00068 19.4 0.4 0.039 13.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KXX76197.1 - 0.0014 18.0 0.1 0.081 12.3 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AIG1 PF04548.16 KXX76197.1 - 0.0021 17.4 0.7 0.65 9.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_18 PF13238.6 KXX76197.1 - 0.0031 18.1 0.2 3.5 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KXX76197.1 - 0.0036 17.0 0.2 0.69 9.6 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF87 PF01935.17 KXX76197.1 - 0.0056 16.8 4.6 0.016 15.3 0.6 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_11 PF13086.6 KXX76197.1 - 0.0094 15.8 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KXX76197.1 - 0.014 15.1 0.1 6.1 6.6 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 KXX76197.1 - 0.02 14.7 1.5 2.3 7.9 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KXX76197.1 - 0.022 15.1 0.4 2.7 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXX76197.1 - 0.022 14.5 0.2 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 KXX76197.1 - 0.035 13.3 0.2 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KXX76197.1 - 0.058 13.0 0.2 10 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXX76197.1 - 0.064 13.6 0.1 8.6 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KXX76197.1 - 0.07 13.6 0.2 7.1 7.1 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KXX76197.1 - 0.072 12.8 0.1 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase AAA_24 PF13479.6 KXX76197.1 - 0.075 12.8 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KXX76197.1 - 0.083 12.5 0.1 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXX76197.1 - 0.085 12.1 0.3 5.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 KXX76197.1 - 0.1 12.3 0.1 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXX76197.1 - 0.13 11.4 0.1 0.84 8.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 KXX76197.1 - 0.16 11.7 0.4 15 5.2 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 KXX76197.1 - 0.19 10.6 0.5 2.9 6.7 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 KXX76197.1 - 0.33 10.8 6.0 6.3 6.7 0.1 3.2 3 0 0 3 3 3 0 NTPase SET PF00856.28 KXX76199.1 - 9.6e-10 39.1 0.0 4.7e-09 36.9 0.0 1.9 1 1 1 2 2 2 1 SET domain DUF4748 PF15932.5 KXX76199.1 - 0.049 13.4 0.7 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) APH PF01636.23 KXX76200.1 - 1.9e-35 122.9 0.1 2.8e-35 122.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KXX76200.1 - 0.036 13.3 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase DUF2263 PF10021.9 KXX76201.1 - 2e-18 67.1 0.6 7.9e-18 65.2 0.6 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) AAA PF00004.29 KXX76202.1 - 2.7e-16 60.2 0.0 4.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX76202.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 KXX76203.1 - 7.7e-12 45.5 0.1 9.6e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXX76204.1 - 0.19 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase FAD_binding_4 PF01565.23 KXX76205.1 - 5.2e-22 78.1 0.5 5.2e-22 78.1 0.5 3.7 3 1 0 3 3 3 1 FAD binding domain BBE PF08031.12 KXX76205.1 - 8.8e-12 44.9 0.5 1.7e-11 44.0 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KXX76206.1 - 8.8e-20 71.0 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76206.1 - 1.5e-13 50.8 0.0 2e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76206.1 - 6.7e-05 22.9 0.0 7.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 KR domain BTG PF07742.12 KXX76206.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 BTG family Putative_PNPOx PF01243.20 KXX76207.1 - 2.5e-05 24.4 0.0 5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GDPD PF03009.17 KXX76208.1 - 6.5e-13 49.0 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SET PF00856.28 KXX76208.1 - 7e-12 46.0 0.1 4e-11 43.6 0.1 2.1 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.16 KXX76209.1 - 4.4e-36 124.5 36.8 4.4e-36 124.5 36.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily GTA_holin_3TM PF11351.8 KXX76210.1 - 1.8 9.2 4.5 2.3 8.8 0.1 2.5 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Methyltransf_33 PF10017.9 KXX76211.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 KXX76211.1 - 0.098 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.27 KXX76212.1 - 4.3e-48 163.4 0.0 7.1e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KXX76212.1 - 1.7e-42 143.9 4.5 2.8e-42 143.2 4.5 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KXX76212.1 - 6.3e-18 64.6 0.0 1.2e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXX76212.1 - 1e-06 29.0 0.1 2.1e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXX76212.1 - 0.00014 21.9 0.0 0.00046 20.2 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 KXX76212.1 - 0.0046 16.6 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Ras family RF3_C PF16658.5 KXX76212.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 KXX76212.1 - 0.16 11.4 0.0 0.38 10.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Glyco_hydro_10 PF00331.20 KXX76213.1 - 9.2e-103 343.7 0.1 1.1e-102 343.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Amidase_6 PF12671.7 KXX76213.1 - 0.018 15.2 1.8 0.03 14.4 1.8 1.4 1 0 0 1 1 1 0 Putative amidase domain Beta-prism_lec PF16458.5 KXX76213.1 - 0.043 13.8 0.5 0.35 10.8 0.2 2.1 2 0 0 2 2 2 0 Beta-prism lectin LEA_6 PF10714.9 KXX76213.1 - 0.063 13.4 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 GYF_2 PF14237.6 KXX76213.1 - 0.065 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 GYF domain 2 F-box-like PF12937.7 KXX76214.1 - 9.2e-08 31.9 0.3 2.5e-07 30.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KXX76214.1 - 0.00014 21.8 0.1 0.00078 19.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.33 KXX76214.1 - 0.0029 17.4 3.5 0.0041 17.0 0.4 2.8 3 1 0 3 3 3 1 F-box domain HALZ PF02183.18 KXX76214.1 - 0.043 14.0 0.2 0.086 13.1 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Clr5 PF14420.6 KXX76215.1 - 4.8e-13 49.1 0.3 9.6e-13 48.1 0.3 1.4 1 0 0 1 1 1 1 Clr5 domain PAS_7 PF12860.7 KXX76215.1 - 0.07 13.3 0.9 0.094 12.9 0.4 1.5 1 1 1 2 2 2 0 PAS fold zf-C2H2_2 PF12756.7 KXX76215.1 - 0.086 13.2 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ank_4 PF13637.6 KXX76216.1 - 7.7e-22 77.4 1.4 1.3e-06 28.8 0.0 5.5 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX76216.1 - 3.1e-19 69.3 1.5 2.8e-07 31.0 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX76216.1 - 2.4e-15 55.1 1.9 0.14 12.8 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 KXX76216.1 - 4.5e-07 30.0 2.7 0.67 10.5 0.0 5.3 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KXX76216.1 - 2.7e-05 24.4 2.6 5.6 7.4 0.0 6.0 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX76217.1 - 3.8e-22 78.7 1.5 3.9e-09 37.0 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX76217.1 - 2e-17 63.3 1.5 2.4e-05 24.8 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX76217.1 - 3.2e-13 48.6 1.2 0.0024 18.2 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KXX76217.1 - 2.7e-10 40.2 5.5 0.0029 18.0 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXX76217.1 - 3.9e-07 30.2 2.4 0.00058 20.1 0.1 3.7 2 2 2 4 4 4 1 Ankyrin repeats (many copies) MIT PF04212.18 KXX76218.1 - 7.5e-14 51.6 3.4 1.6e-13 50.5 3.4 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain NAD_binding_8 PF13450.6 KXX76219.1 - 1.5e-13 50.7 0.1 3.1e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX76219.1 - 0.00011 22.0 0.3 0.00047 19.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXX76219.1 - 0.011 14.8 0.2 0.029 13.4 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXX76219.1 - 0.019 14.9 0.7 0.3 11.1 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXX76219.1 - 0.031 13.5 0.1 0.072 12.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KXX76219.1 - 0.037 12.9 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KXX76219.1 - 0.043 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2834 PF11196.8 KXX76220.1 - 1.3e-07 31.9 18.8 0.0021 18.4 11.1 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) DUF3397 PF11877.8 KXX76220.1 - 1.9 8.7 14.2 1.3 9.2 0.3 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3397) Terpene_synth_C PF03936.16 KXX76221.1 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HTH_28 PF13518.6 KXX76221.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_23 PF13489.6 KXX76222.1 - 1.8e-13 50.7 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX76222.1 - 4.1e-06 27.4 0.0 1.3e-05 25.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX76222.1 - 0.00013 22.6 0.0 0.0012 19.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXX76222.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_11 PF08241.12 KXX76222.1 - 0.085 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXX76222.1 - 0.099 12.4 0.0 0.59 9.9 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_4 PF02390.17 KXX76222.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KXX76222.1 - 0.21 10.9 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX76222.1 - 0.25 10.9 0.0 0.52 9.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Retrotrans_gag PF03732.17 KXX76223.1 - 0.0024 18.1 0.0 0.0032 17.7 0.0 1.3 1 1 0 1 1 1 1 Retrotransposon gag protein Ank_2 PF12796.7 KXX76224.1 - 1.4e-44 150.5 0.7 1.8e-08 34.8 0.0 7.1 3 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX76224.1 - 6.7e-35 119.0 4.1 4.1e-06 27.2 0.1 9.1 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX76224.1 - 5.1e-32 109.5 6.5 4.9e-06 26.7 0.0 10.1 6 3 4 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX76224.1 - 8.6e-25 84.1 7.8 0.13 12.9 0.0 11.3 12 0 0 12 12 10 6 Ankyrin repeat Ank PF00023.30 KXX76224.1 - 6.3e-23 80.2 13.8 0.00055 20.3 0.0 8.9 10 0 0 10 10 8 4 Ankyrin repeat SPRY PF00622.28 KXX76224.1 - 3.1e-12 46.7 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain AAA_16 PF13191.6 KXX76224.1 - 1.9e-09 38.1 0.1 6.3e-07 29.9 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXX76224.1 - 1.3e-05 25.2 0.0 4.8e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXX76224.1 - 0.00019 21.7 0.4 0.0014 18.9 0.4 2.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXX76224.1 - 0.022 15.1 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KXX76224.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KXX76224.1 - 0.026 14.6 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXX76224.1 - 0.044 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXX76224.1 - 0.066 12.9 0.1 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.6 KXX76224.1 - 0.11 12.8 0.0 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KXX76224.1 - 0.11 11.7 0.0 2.7 7.2 0.0 2.4 1 1 0 2 2 2 0 KAP family P-loop domain ResIII PF04851.15 KXX76224.1 - 0.12 12.4 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 KXX76224.1 - 0.14 12.5 0.1 0.81 10.1 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXX76224.1 - 0.18 11.8 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-MYND PF01753.18 KXX76225.1 - 2.2e-11 43.6 13.3 5.6e-11 42.3 13.3 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXX76225.1 - 0.035 14.4 8.6 0.035 14.4 8.6 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KXX76225.1 - 0.33 11.1 7.5 0.74 10.0 7.5 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.7 KXX76225.1 - 2 9.5 6.8 4.8 8.3 6.9 1.5 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins p450 PF00067.22 KXX76226.1 - 2.6e-50 171.5 0.0 3.3e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chromate_transp PF02417.15 KXX76227.1 - 1.1e-29 103.6 16.1 2.5e-20 73.2 6.8 2.4 3 0 0 3 3 3 2 Chromate transporter DUF3995 PF13160.6 KXX76227.1 - 9 6.7 11.9 8.3 6.8 7.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) AXE1 PF05448.12 KXX76228.1 - 0.015 14.0 0.1 0.023 13.4 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAR PF03114.18 KXX76229.1 - 1.2e-67 228.1 3.6 1.4e-67 227.8 3.6 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KXX76229.1 - 0.0022 18.7 0.6 0.019 15.7 0.0 2.7 3 1 0 3 3 3 1 CP12 domain SVIP PF15811.5 KXX76229.1 - 1.4 9.4 4.7 0.52 10.8 0.7 2.2 2 0 0 2 2 2 0 Small VCP/p97-interacting protein BAR PF03114.18 KXX76230.1 - 1.9e-57 194.7 3.8 2.2e-57 194.4 3.8 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KXX76230.1 - 3.2e-06 26.5 1.2 5.4e-06 25.8 1.2 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking HAUS6_N PF14661.6 KXX76230.1 - 6.1 6.4 7.3 1.5 8.3 4.0 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.14 KXX76230.1 - 7.3 6.9 8.9 1.4 9.2 5.0 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CAP PF00188.26 KXX76232.1 - 7.4e-16 59.1 0.2 9.9e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HdeA PF06411.11 KXX76232.1 - 0.076 13.2 0.3 0.18 12.0 0.3 1.6 1 1 0 1 1 1 0 HdeA/HdeB family adh_short PF00106.25 KXX76234.1 - 2e-06 27.4 0.0 0.0058 16.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXX76234.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 KXX76234.1 - 0.088 12.7 0.1 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H-binding Aldedh PF00171.22 KXX76235.1 - 1.3e-135 452.6 0.0 1.5e-135 452.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXX76235.1 - 0.12 11.4 0.0 0.34 9.9 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) MCH PF02289.16 KXX76235.1 - 0.24 10.7 1.1 0.3 10.3 0.1 1.5 2 0 0 2 2 2 0 Cyclohydrolase (MCH) Chitin_bind_1 PF00187.19 KXX76236.1 - 4.4e-09 36.7 57.8 5.4e-08 33.2 18.9 3.3 3 0 0 3 3 3 2 Chitin recognition protein Glyco_hydro_18 PF00704.28 KXX76237.1 - 7e-10 39.1 0.0 8.1e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AltA1 PF16541.5 KXX76238.1 - 3.7e-26 92.2 2.8 5.9e-26 91.5 2.8 1.3 1 0 0 1 1 1 1 Alternaria alternata allergen 1 DUF1996 PF09362.10 KXX76239.1 - 1e-82 277.7 0.7 1.2e-82 277.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TauD PF02668.16 KXX76240.1 - 7.9e-30 104.5 0.4 1e-29 104.2 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pept_tRNA_hydro PF01195.19 KXX76242.1 - 6.4e-29 101.1 0.0 8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Cyclin_C_2 PF16899.5 KXX76243.1 - 9e-34 116.0 0.0 1.3e-32 112.3 0.0 2.4 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KXX76243.1 - 3.6e-05 23.5 0.0 7.6e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain UQ_con PF00179.26 KXX76244.1 - 3.2e-24 85.2 0.0 5.6e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KXX76244.1 - 3.8e-05 23.5 0.0 0.043 13.7 0.0 2.6 3 0 0 3 3 3 2 UEV domain Pkinase PF00069.25 KXX76245.1 - 1.3e-51 175.5 0.0 1.9e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76245.1 - 9.8e-25 87.3 0.4 1.5e-23 83.4 0.4 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 KXX76245.1 - 0.0018 18.0 0.4 0.22 11.1 0.2 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KXX76245.1 - 0.01 15.2 0.1 0.037 13.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KXX76245.1 - 0.012 14.4 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase IBN_N PF03810.19 KXX76246.1 - 1.8e-12 47.0 2.5 2.2e-10 40.3 0.0 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KXX76246.1 - 1.1e-08 34.4 0.0 2.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 KXX76246.1 - 3.9e-06 27.0 2.6 0.0002 21.5 0.1 4.4 5 0 0 5 5 5 1 Exportin 1-like protein Importin_rep_6 PF18829.1 KXX76246.1 - 0.0043 17.2 0.1 0.017 15.3 0.1 2.1 1 0 0 1 1 1 1 Importin repeat 6 Cnd1 PF12717.7 KXX76246.1 - 0.056 13.5 0.3 0.24 11.5 0.1 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_C PF14225.6 KXX76246.1 - 0.064 13.1 1.2 5.6 6.8 0.1 3.3 3 0 0 3 3 3 0 Cell morphogenesis C-terminal DUF2013 PF09431.10 KXX76246.1 - 0.14 12.4 0.3 0.5 10.5 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) TMCO5 PF14992.6 KXX76248.1 - 0.19 11.3 1.2 0.28 10.7 1.2 1.1 1 0 0 1 1 1 0 TMCO5 family ISN1 PF06437.11 KXX76249.1 - 3.3e-201 668.5 0.0 3.7e-201 668.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase KAR9 PF08580.10 KXX76250.1 - 9.7 4.6 8.6 11 4.4 8.6 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ribosomal_L21e PF01157.18 KXX76251.1 - 1.2e-46 156.7 6.5 1.6e-46 156.3 5.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e OHA PF14418.6 KXX76251.1 - 0.07 12.9 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 OST-HTH Associated domain DUF5486 PF17588.2 KXX76251.1 - 0.077 12.9 0.2 0.077 12.9 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5486) S4 PF01479.25 KXX76252.1 - 1.2e-12 47.3 1.5 1.2e-12 47.3 1.5 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KXX76252.1 - 1.5e-05 25.9 0.0 2.9e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 KXX76252.1 - 0.033 14.3 0.3 0.82 9.8 0.0 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Slu7 PF11708.8 KXX76253.1 - 3e-70 237.1 14.3 3.4e-69 233.6 14.3 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 KXX76253.1 - 0.0014 18.6 4.8 0.0028 17.7 4.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXX76253.1 - 0.0029 17.3 0.1 0.0066 16.2 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KXX76253.1 - 0.19 11.6 3.8 0.46 10.4 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle CCDC71L PF15374.6 KXX76253.1 - 3.9 6.6 6.3 0.33 10.2 1.5 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L DNA_pol_B PF00136.21 KXX76254.1 - 9.5e-94 314.7 0.0 4.8e-86 289.3 0.1 2.2 2 0 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXX76254.1 - 1.4e-19 70.4 0.0 6.6e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXX76254.1 - 9.4e-13 48.4 2.4 2.2e-12 47.2 2.4 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta XkdW PF09636.10 KXX76254.1 - 0.068 13.3 0.4 0.24 11.5 0.4 1.9 1 0 0 1 1 1 0 XkdW protein DUF3439 PF11921.8 KXX76254.1 - 0.92 9.5 9.3 2.1 8.3 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Gly_transf_sug PF04488.15 KXX76255.1 - 1e-13 51.7 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KXX76255.1 - 0.013 14.9 0.0 0.042 13.2 0.0 1.8 1 1 1 2 2 2 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 KXX76255.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain MMM1 PF10296.9 KXX76256.1 - 3.4e-06 26.4 1.0 6.6e-05 22.1 0.1 2.3 1 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 IMS PF00817.20 KXX76257.1 - 1.1e-43 148.8 0.0 1.7e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXX76257.1 - 2.2e-14 54.2 0.0 4.9e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KXX76257.1 - 5.2e-11 41.9 5.6 1.1e-10 41.0 5.6 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KXX76257.1 - 0.032 14.6 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif HTH_33 PF13592.6 KXX76257.1 - 0.098 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix U-box PF04564.15 KXX76258.1 - 3.9e-21 75.0 0.0 9.9e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KXX76258.1 - 2.4e-12 45.9 5.2 0.0055 16.7 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX76258.1 - 1.4e-11 43.7 3.2 0.0033 17.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXX76258.1 - 3.1e-08 33.1 3.4 1.2e-05 24.9 0.1 2.7 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 KXX76258.1 - 1.3e-07 32.0 3.8 0.00036 21.0 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX76258.1 - 1.2e-06 29.0 9.3 0.00032 21.3 1.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXX76258.1 - 2.2e-06 27.6 2.7 0.0059 16.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX76258.1 - 0.00037 21.1 9.2 0.27 12.1 0.2 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX76258.1 - 0.00072 19.8 8.0 0.027 14.7 3.7 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KXX76258.1 - 0.00092 19.9 13.6 0.0012 19.5 12.7 1.7 2 0 0 2 2 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_9 PF13371.6 KXX76258.1 - 0.0014 18.7 1.6 0.0052 16.9 1.6 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX76258.1 - 0.0015 18.7 3.0 0.0041 17.3 3.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4745 PF15923.5 KXX76258.1 - 0.0065 16.5 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4745) TPR_7 PF13176.6 KXX76258.1 - 0.0083 16.1 3.3 1.3 9.3 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXX76258.1 - 0.038 14.3 0.7 0.22 11.9 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Nse PF11789.8 KXX76258.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Peptidase_M28 PF04389.17 KXX76259.1 - 8.7e-29 100.6 0.1 1.3e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXX76259.1 - 1.3e-06 28.2 0.1 2.5e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PLDc_2 PF13091.6 KXX76260.1 - 3.4e-19 69.0 0.0 3.5e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXX76260.1 - 0.00025 21.1 0.1 0.18 12.0 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Inhibitor_Mig-6 PF11555.8 KXX76260.1 - 0.064 13.4 4.4 0.28 11.3 4.0 2.2 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Regulator_TrmB PF11495.8 KXX76260.1 - 0.2 10.8 0.2 2.3 7.3 0.1 2.4 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB F-box-like PF12937.7 KXX76261.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX76261.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain Glyco_transf_22 PF03901.17 KXX76262.1 - 3.1e-89 300.1 20.5 3.6e-89 299.9 20.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 KXX76263.1 - 1.9e-43 147.9 0.2 4e-43 146.8 0.2 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Macoilin PF09726.9 KXX76263.1 - 0.2 10.2 2.0 0.26 9.8 2.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 KXX76263.1 - 4.5 6.0 4.1 7.2 5.3 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SH3_9 PF14604.6 KXX76264.1 - 1.8e-11 43.7 0.4 3.5e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Podoplanin PF05808.11 KXX76264.1 - 1.9e-08 34.6 2.9 3.4e-08 33.7 2.9 1.3 1 0 0 1 1 1 1 Podoplanin SH3_1 PF00018.28 KXX76264.1 - 8.3e-07 28.5 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXX76264.1 - 3.2e-05 23.5 0.0 5.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Glycophorin_A PF01102.18 KXX76264.1 - 0.0013 19.0 0.2 0.0026 18.0 0.2 1.5 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.6 KXX76264.1 - 0.0019 18.1 0.4 0.004 17.1 0.4 1.4 1 0 0 1 1 1 1 TMEM154 protein family LapA_dom PF06305.11 KXX76264.1 - 0.016 15.0 0.2 0.028 14.2 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2407_C PF13373.6 KXX76264.1 - 0.026 14.7 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain RIFIN PF02009.16 KXX76264.1 - 0.029 14.3 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 KXX76264.1 - 0.031 13.1 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 KXX76264.1 - 0.037 13.9 0.2 0.064 13.2 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.12 KXX76264.1 - 0.043 13.6 0.2 0.072 12.9 0.2 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 KXX76264.1 - 0.11 12.2 0.2 0.19 11.5 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Vpu PF00558.19 KXX76264.1 - 1.2 9.0 3.5 0.69 9.7 1.5 1.5 1 1 1 2 2 2 0 Vpu protein Helo_like_N PF17111.5 KXX76267.1 - 5.1e-93 310.2 7.8 1.7e-84 282.4 0.9 2.1 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXX76267.1 - 0.00036 20.7 4.8 0.001 19.3 0.0 3.1 2 1 2 4 4 4 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 KXX76267.1 - 0.04 14.4 4.7 0.077 13.5 0.5 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 KXX76267.1 - 0.47 10.3 9.2 7.9 6.3 0.1 3.6 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF842 PF05811.13 KXX76267.1 - 1.2 8.8 8.8 6.5 6.5 0.4 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Baculo_F PF12259.8 KXX76267.1 - 1.5 7.3 3.9 6.7 5.1 1.3 2.0 2 0 0 2 2 2 0 Baculovirus F protein Tropomyosin_1 PF12718.7 KXX76267.1 - 1.8 8.7 16.3 3.5 7.8 6.5 3.1 2 1 1 3 3 3 0 Tropomyosin like NUC153 PF08159.12 KXX76268.1 - 6e-16 58.0 6.9 6.9e-15 54.6 0.3 3.6 3 0 0 3 3 3 2 NUC153 domain SnoaL PF07366.12 KXX76269.1 - 0.16 11.7 0.1 3.1 7.6 0.0 2.2 1 1 0 2 2 2 0 SnoaL-like polyketide cyclase Cu_bind_like PF02298.17 KXX76270.1 - 0.21 11.6 0.2 0.7 9.9 0.2 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain AFG1_ATPase PF03969.16 KXX76272.1 - 2.1e-96 323.0 0.0 9.6e-92 307.6 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KXX76272.1 - 2.7e-05 24.6 0.0 0.019 15.3 0.0 2.7 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXX76272.1 - 0.00047 20.5 0.1 0.0075 16.5 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KXX76272.1 - 0.0014 18.6 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 KXX76272.1 - 0.0024 17.8 0.3 0.46 10.3 0.0 2.8 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_5 PF07728.14 KXX76272.1 - 0.0041 17.1 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXX76272.1 - 0.012 15.6 0.0 0.037 13.9 0.0 1.9 1 1 0 1 1 1 0 NACHT domain TsaE PF02367.17 KXX76272.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KXX76272.1 - 0.042 14.3 0.0 0.26 11.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXX76272.1 - 0.067 13.6 0.2 0.25 11.8 0.0 2.1 2 1 0 2 2 2 0 RNA helicase Acetyltransf_7 PF13508.7 KXX76273.1 - 7.4e-06 26.3 0.1 3.5e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXX76273.1 - 3.6e-05 23.8 0.1 0.0026 17.8 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX76273.1 - 0.00033 20.9 0.0 0.0011 19.2 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX76273.1 - 0.0044 16.9 0.0 0.08 12.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX76273.1 - 0.018 15.0 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 KXX76273.1 - 0.094 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cpn60_TCP1 PF00118.24 KXX76274.1 - 4.7e-151 503.8 15.6 5.3e-151 503.6 15.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_int_SAM_1 PF02899.17 KXX76274.1 - 0.17 12.2 0.1 0.83 10.0 0.0 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain ProRS-C_1 PF09180.11 KXX76275.1 - 1e-21 76.9 0.1 2.1e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KXX76275.1 - 4.9e-21 75.5 0.0 9.1e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXX76275.1 - 2e-16 59.9 0.0 4.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Exo5 PF09810.9 KXX76276.1 - 4e-123 411.5 0.0 5.2e-123 411.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KXX76276.1 - 5.4e-05 23.2 1.0 0.25 11.2 0.0 3.0 3 1 0 3 3 3 2 PD-(D/E)XK nuclease superfamily Ferric_reduct PF01794.19 KXX76277.1 - 1.7e-18 66.9 14.4 1.7e-18 66.9 14.4 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXX76277.1 - 1.8e-15 57.4 0.0 7.4e-15 55.4 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXX76277.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain DM13 PF10517.9 KXX76278.1 - 2.1e-14 54.0 0.0 2.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Electron transfer DM13 Glyco_hydro_79C PF16862.5 KXX76279.1 - 2.4e-17 63.7 0.0 5.8e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain SAT PF16073.5 KXX76280.1 - 3e-76 256.3 0.1 5.3e-75 252.2 0.1 2.7 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KXX76280.1 - 2.8e-74 249.9 0.0 5.6e-74 248.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXX76280.1 - 1.6e-40 139.6 0.0 3.5e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX76280.1 - 1.8e-35 121.5 0.4 5.2e-35 120.0 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KXX76280.1 - 1.6e-24 87.3 0.3 1.3e-22 81.1 0.0 3.1 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KXX76280.1 - 6.7e-24 84.0 2.2 4.2e-11 43.0 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KXX76280.1 - 1.5e-12 47.4 0.0 4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KXX76280.1 - 0.00023 21.9 4.3 0.28 11.7 0.1 3.6 3 0 0 3 3 3 2 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KXX76280.1 - 0.00037 20.9 0.0 0.00097 19.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXX76280.1 - 0.00071 19.0 0.2 0.0032 16.9 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Hydrolase_4 PF12146.8 KXX76280.1 - 0.0079 15.5 0.1 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DNA_pol_E_B PF04042.16 KXX76281.1 - 2.3e-69 233.0 0.0 3.3e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Cu-oxidase_2 PF07731.14 KXX76282.1 - 1e-41 141.8 10.8 1.2e-36 125.5 2.1 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXX76282.1 - 7.5e-33 113.1 7.6 8.8e-30 103.2 0.3 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KXX76282.1 - 1.2e-22 80.7 2.5 3.4e-22 79.3 0.2 2.6 3 0 0 3 3 3 1 Multicopper oxidase PC4 PF02229.16 KXX76283.1 - 1.1e-22 79.4 0.1 1.8e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) MFS_1 PF07690.16 KXX76285.1 - 5.8e-34 117.6 26.4 5.8e-34 117.6 26.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ALMT PF11744.8 KXX76285.1 - 1.9 7.2 4.0 2.8 6.7 4.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CorA PF01544.18 KXX76286.1 - 4.6e-13 49.1 3.2 2.5e-11 43.4 3.2 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Gly_transf_sug PF04488.15 KXX76287.1 - 5.4e-11 43.0 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KXX76287.1 - 0.00061 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain PBP PF01161.20 KXX76288.1 - 3.9e-12 46.6 0.1 4.8e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Gram_pos_anchor PF00746.21 KXX76290.1 - 0.055 13.4 1.1 0.055 13.4 1.1 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Podoplanin PF05808.11 KXX76290.1 - 0.083 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Podoplanin Cation_efflux PF01545.21 KXX76291.1 - 7.1e-12 45.5 6.7 7.9e-12 45.3 6.3 1.3 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXX76291.1 - 1.3e-08 34.8 0.2 3.4e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter WD40 PF00400.32 KXX76293.1 - 1.2e-25 89.2 2.6 3.7e-09 37.1 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX76293.1 - 4.9e-09 36.4 0.0 0.0014 18.9 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXX76293.1 - 0.00013 21.8 0.1 2.5 8.1 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXX76293.1 - 0.00083 18.4 0.4 0.046 12.7 0.4 2.5 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXX76293.1 - 0.022 13.4 0.0 3.7 6.1 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DPPIV_N PF00930.21 KXX76293.1 - 0.03 13.1 0.2 13 4.5 0.0 3.0 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 KXX76293.1 - 0.061 13.1 0.1 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PXA PF02194.15 KXX76294.1 - 8.3e-33 113.9 0.0 2.1e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KXX76294.1 - 5.5e-23 81.7 1.3 9.7e-23 80.9 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KXX76294.1 - 2.3e-07 30.8 0.0 7.8e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 PX domain NACHT_N PF17100.5 KXX76295.1 - 6.3e-48 163.5 3.4 2.8e-30 105.9 0.4 2.1 1 1 1 2 2 2 2 N-terminal domain of NWD NACHT-NTPase Cyt_bd_oxida_I PF01654.17 KXX76295.1 - 0.1 11.2 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I DUF1989 PF09347.10 KXX76297.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) NB-ARC PF00931.22 KXX76298.1 - 3.6e-10 39.4 0.0 8e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXX76298.1 - 0.0081 16.6 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_12 PF13424.6 KXX76299.1 - 6.9e-20 71.1 17.6 2.8e-09 37.1 1.7 3.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXX76299.1 - 4.1e-15 54.8 9.0 2.6e-05 23.8 0.1 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXX76299.1 - 3.4e-12 45.6 8.1 0.012 15.8 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX76299.1 - 4.8e-12 45.0 15.0 0.0015 18.5 0.2 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX76299.1 - 1e-10 40.8 9.5 0.034 14.2 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXX76299.1 - 1.3e-10 41.2 13.3 0.00012 22.5 0.2 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXX76299.1 - 1.6e-10 40.5 16.5 0.0067 16.3 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXX76299.1 - 5.6e-09 36.4 9.9 0.0012 19.3 0.3 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX76299.1 - 1.5e-08 35.1 7.3 0.03 14.9 0.1 4.1 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.14 KXX76299.1 - 6.2e-08 32.5 9.1 0.18 12.5 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXX76299.1 - 2e-06 27.4 8.2 0.026 14.2 0.3 4.9 5 1 1 6 6 5 3 TPR repeat TPR_MalT PF17874.1 KXX76299.1 - 4e-05 23.2 5.4 8.8e-05 22.0 5.4 1.5 1 1 0 1 1 1 1 MalT-like TPR region DUF3856 PF12968.7 KXX76299.1 - 4.5e-05 23.5 2.6 0.0013 18.8 0.3 2.8 1 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 KXX76299.1 - 0.0005 20.2 2.1 0.12 12.7 0.0 4.1 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KXX76299.1 - 0.0028 17.8 0.1 11 6.6 0.0 3.9 4 0 0 4 4 3 0 PPR repeat RPN7 PF10602.9 KXX76299.1 - 0.0032 17.2 4.4 0.77 9.4 0.1 3.3 1 1 2 4 4 4 2 26S proteasome subunit RPN7 TPR_17 PF13431.6 KXX76299.1 - 0.012 16.0 2.8 1.2e+02 3.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KXX76299.1 - 0.019 15.0 2.4 4.9 7.3 0.0 3.6 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain DUF218 PF02698.17 KXX76299.1 - 0.052 13.6 2.0 1.2 9.2 2.0 2.2 1 1 0 1 1 1 0 DUF218 domain TPR_20 PF14561.6 KXX76299.1 - 0.053 13.8 4.6 0.68 10.3 0.2 3.2 1 1 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.7 KXX76299.1 - 0.058 13.1 0.0 20 5.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 KXX76299.1 - 0.14 12.9 11.1 2.3 9.0 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 KXX76300.1 - 8.3e-18 64.7 0.0 5.7e-10 39.0 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76300.1 - 1.2e-06 28.0 0.0 0.084 12.1 0.1 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXX76300.1 - 0.019 14.3 0.0 0.065 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Sec63 PF02889.16 KXX76301.1 - 4.4e-27 94.9 0.0 6.1e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KXX76301.1 - 8.7e-26 90.7 0.0 5.8e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KXX76301.1 - 2.2e-12 47.3 0.0 6.5e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXX76301.1 - 8.5e-10 39.0 0.0 8.7e-09 35.7 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 KXX76301.1 - 4.4e-06 27.2 0.0 2.9e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_19 PF13245.6 KXX76301.1 - 0.0011 19.3 0.2 0.015 15.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXX76301.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX76301.1 - 0.021 15.1 0.1 0.078 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain Cdd1 PF11731.8 KXX76301.1 - 0.07 13.4 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus UvrD-helicase PF00580.21 KXX76301.1 - 0.081 12.4 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DNA_pol_lambd_f PF10391.9 KXX76301.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda MFS_1 PF07690.16 KXX76302.1 - 1.3e-26 93.4 30.6 1.3e-26 93.4 30.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.14 KXX76303.1 - 2.5e-25 89.6 0.0 3.4e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Exo_endo_phos PF03372.23 KXX76304.1 - 6.2e-07 29.2 0.0 1.3e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_23 PF13489.6 KXX76305.1 - 3.5e-21 75.7 0.0 4.4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX76305.1 - 8.2e-16 58.6 0.0 2.5e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX76305.1 - 1.3e-15 57.9 0.0 4.3e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX76305.1 - 1.4e-13 50.9 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX76305.1 - 2.4e-13 50.6 0.0 5e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX76305.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 KXX76305.1 - 0.00043 19.4 0.0 0.0005 19.2 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DUF938 PF06080.12 KXX76305.1 - 0.00046 20.0 0.0 0.0006 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 KXX76305.1 - 0.0061 15.7 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 KXX76305.1 - 0.015 14.4 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase MTS PF05175.14 KXX76305.1 - 0.026 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_33 PF10017.9 KXX76305.1 - 0.03 13.5 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent PCMT PF01135.19 KXX76305.1 - 0.043 13.5 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 KXX76305.1 - 0.072 12.2 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin CMAS PF02353.20 KXX76305.1 - 0.074 12.3 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 KXX76305.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.19 KXX76305.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KXX76305.1 - 0.14 13.2 0.0 0.27 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 KXX76305.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 2 0 0 2 2 1 0 DNA methylase Methyltransf_17 PF12692.7 KXX76305.1 - 0.15 12.1 0.0 1.4 8.9 0.0 2.1 1 1 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_16 PF10294.9 KXX76305.1 - 0.17 11.6 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Epimerase PF01370.21 KXX76308.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.22 KXX76309.1 - 1.1e-58 199.1 0.0 1.3e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 KXX76310.1 - 1.4e-07 31.7 0.0 2.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXX76310.1 - 1e-05 25.9 0.0 2.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX76310.1 - 1.6e-05 24.9 0.0 3.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX76310.1 - 0.0047 17.1 0.0 0.0084 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX76310.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Importin_rep_4 PF18808.1 KXX76310.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Importin repeat Acetyltransf_3 PF13302.7 KXX76311.1 - 3e-31 108.9 0.0 4.1e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX76311.1 - 0.00083 19.6 0.0 0.004 17.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family GFO_IDH_MocA PF01408.22 KXX76312.1 - 4.6e-16 59.7 0.1 1.2e-15 58.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXX76312.1 - 0.0035 17.4 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Smoothelin PF12510.8 KXX76312.1 - 3.4 7.8 4.7 2.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein DAO PF01266.24 KXX76313.1 - 7e-23 81.8 1.6 8.4e-23 81.5 1.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase tRNA-synt_1 PF00133.22 KXX76314.1 - 1.3e-209 697.5 0.0 3e-208 692.9 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXX76314.1 - 9.3e-26 90.6 0.3 9.3e-26 90.6 0.3 2.5 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KXX76314.1 - 1.1e-11 44.6 0.0 2e-07 30.7 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KXX76314.1 - 2.4e-11 43.0 0.9 9e-05 21.4 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KXX76314.1 - 0.012 15.0 0.0 0.28 10.5 0.0 2.8 2 1 1 3 3 3 0 tRNA synthetases class I (C) catalytic domain ABC2_membrane_3 PF12698.7 KXX76315.1 - 0.065 12.3 0.7 0.069 12.2 0.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein p450 PF00067.22 KXX76317.1 - 2.1e-06 26.8 0.0 2.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.18 KXX76318.1 - 7e-08 32.1 5.0 4.8e-07 29.4 5.0 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SH3_3 PF08239.11 KXX76319.1 - 1.9e-06 28.1 0.1 3.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KXX76319.1 - 0.023 14.5 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial SH3 domain Dioxygenase_C PF00775.21 KXX76321.1 - 4.2e-09 36.1 0.8 9.5e-09 34.9 0.8 1.6 1 1 0 1 1 1 1 Dioxygenase 5-FTHF_cyc-lig PF01812.20 KXX76322.1 - 1.6e-28 99.8 0.0 2.1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PLDc_2 PF13091.6 KXX76323.1 - 1.8e-17 63.5 0.0 1.4e-06 28.2 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KXX76323.1 - 4e-13 48.9 0.1 3.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif FR47 PF08445.10 KXX76324.1 - 5.3e-09 35.9 0.0 8.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KXX76324.1 - 3.7e-07 30.1 0.0 5.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX76324.1 - 1.3e-06 28.7 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX76324.1 - 0.00019 21.8 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXX76324.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PDZ_assoc PF10600.9 KXX76325.1 - 0.087 13.7 13.8 0.62 10.9 0.4 3.6 3 0 0 3 3 3 0 PDZ-associated domain of NMDA receptors LCE PF14672.6 KXX76325.1 - 3.3 8.4 10.0 0.1 13.2 2.2 2.6 2 1 0 2 2 2 0 Late cornified envelope Sec62 PF03839.16 KXX76326.1 - 1.4e-70 237.2 0.8 1.4e-70 237.2 0.8 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 SelP_N PF04592.14 KXX76326.1 - 4.1 6.8 10.7 7.7 5.8 10.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.16 KXX76327.1 - 2.7e-35 121.9 23.1 3.3e-27 95.4 3.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX76327.1 - 5.2e-09 35.5 5.8 5.2e-09 35.5 5.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXX76327.1 - 0.00085 18.3 2.1 0.00085 18.3 2.1 2.4 2 0 0 2 2 2 1 MFS_1 like family BT1 PF03092.16 KXX76327.1 - 0.18 10.0 5.4 0.86 7.8 0.2 2.2 2 0 0 2 2 2 0 BT1 family DUF3087 PF11286.8 KXX76327.1 - 1.1 8.7 2.3 0.86 9.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Inositol_P PF00459.25 KXX76328.1 - 2.8e-60 204.1 0.0 3.2e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family LSM PF01423.22 KXX76329.1 - 5.7e-16 58.0 0.4 6.7e-16 57.7 0.4 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXX76329.1 - 0.0022 17.6 0.2 0.0034 17.0 0.2 1.3 1 0 0 1 1 1 1 Hfq protein Thioredoxin PF00085.20 KXX76330.1 - 1.5e-39 134.2 0.0 1.2e-24 86.3 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KXX76330.1 - 9.6e-11 41.9 0.0 0.0047 16.9 0.0 3.6 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KXX76330.1 - 2.7e-06 27.8 0.7 0.065 13.7 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXX76330.1 - 2.1e-05 24.7 0.6 0.047 14.0 0.0 4.4 4 2 0 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 KXX76330.1 - 0.0044 16.9 1.2 0.58 10.1 0.1 3.8 3 1 1 4 4 4 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KXX76330.1 - 0.0054 16.9 1.3 0.024 14.8 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 KXX76330.1 - 0.022 14.1 0.2 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family HyaE PF07449.11 KXX76330.1 - 0.095 12.7 0.0 10 6.1 0.0 2.9 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Tyr-DNA_phospho PF06087.12 KXX76331.1 - 3e-163 543.7 0.0 3.8e-163 543.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc PF00614.22 KXX76331.1 - 0.15 12.3 0.2 9 6.7 0.3 2.8 2 0 0 2 2 2 0 Phospholipase D Active site motif DUF2749 PF10907.8 KXX76332.1 - 1.4 9.2 3.7 2.9 8.1 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) His_Phos_2 PF00328.22 KXX76333.1 - 1.6e-67 228.5 0.0 2e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) OPT PF03169.15 KXX76334.1 - 2.8e-205 683.6 34.8 3.2e-205 683.4 34.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ACBP PF00887.19 KXX76335.1 - 3.2e-21 75.3 0.8 3.7e-21 75.1 0.8 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein VASt PF16016.5 KXX76336.1 - 3.4e-38 131.4 0.0 5.5e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXX76336.1 - 4.3e-24 84.6 0.0 8.8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain NOA36 PF06524.12 KXX76336.1 - 0.026 13.9 0.1 0.026 13.9 0.1 1.7 2 0 0 2 2 2 0 NOA36 protein CSN5_C PF18323.1 KXX76336.1 - 2 9.4 4.6 1.6 9.7 0.3 3.0 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain CENP-Q PF13094.6 KXX76337.1 - 0.00082 19.6 2.7 0.00082 19.6 2.7 3.2 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF812 PF05667.11 KXX76337.1 - 0.0038 16.2 0.2 0.0056 15.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DivIVA PF05103.13 KXX76337.1 - 0.0091 16.1 5.4 0.017 15.2 0.8 2.4 2 0 0 2 2 2 1 DivIVA protein Atg14 PF10186.9 KXX76337.1 - 0.013 14.6 2.0 0.02 14.0 2.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 KXX76337.1 - 0.023 14.9 5.1 1 9.6 0.5 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 KXX76337.1 - 0.068 12.5 2.3 0.16 11.3 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nnf1 PF03980.14 KXX76337.1 - 0.074 13.4 4.6 2.1 8.8 0.1 3.2 3 0 0 3 3 3 0 Nnf1 BST2 PF16716.5 KXX76337.1 - 0.21 12.2 4.6 14 6.3 1.6 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 CdvA PF18822.1 KXX76337.1 - 0.34 10.7 4.7 4.8 7.0 0.7 2.7 2 0 0 2 2 2 0 CdvA-like coiled-coil domain HAUS-augmin3 PF14932.6 KXX76337.1 - 0.47 10.0 6.3 4.9 6.6 0.2 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 MPS2 PF17060.5 KXX76337.1 - 0.51 9.6 2.8 0.4 9.9 0.9 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 Ax_dynein_light PF10211.9 KXX76337.1 - 0.63 10.0 11.4 0.82 9.6 6.3 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Matrilin_ccoil PF10393.9 KXX76337.1 - 0.67 9.9 3.9 20 5.1 0.4 2.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin TMF_DNA_bd PF12329.8 KXX76337.1 - 1.1 9.2 9.6 0.3 11.1 1.6 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fmp27_WPPW PF10359.9 KXX76337.1 - 2 7.2 6.1 5.3 5.8 1.7 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4201 PF13870.6 KXX76337.1 - 2.1 8.0 9.8 8.5 6.1 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) UPF0242 PF06785.11 KXX76337.1 - 4.2 7.4 8.2 10 6.2 7.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KXX76337.1 - 5.3 7.8 8.9 6.9 7.4 2.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KXX76337.1 - 5.9 7.2 10.4 2.3 8.5 6.9 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain DHR10 PF18595.1 KXX76337.1 - 6.4 6.9 25.5 0.065 13.3 13.6 2.5 3 0 0 3 3 2 0 Designed helical repeat protein 10 domain SlyX PF04102.12 KXX76337.1 - 6.6 7.4 11.0 1.1 9.9 3.7 2.9 3 0 0 3 3 3 0 SlyX End3 PF12761.7 KXX76339.1 - 2.3e-79 266.2 3.6 3.1e-79 265.8 3.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KXX76339.1 - 8.5e-49 163.8 0.0 2.9e-48 162.1 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KXX76339.1 - 4.5e-07 29.0 0.3 9.6e-07 27.9 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXX76339.1 - 1.1e-05 25.8 0.0 4.3e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KXX76339.1 - 0.0012 18.6 0.3 0.0041 16.9 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KXX76339.1 - 0.0021 17.9 0.1 0.0041 16.9 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXX76339.1 - 0.024 14.1 0.2 0.069 12.7 0.2 1.8 1 0 0 1 1 1 0 EF hand UPF0242 PF06785.11 KXX76339.1 - 0.37 10.9 4.7 0.67 10.0 4.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CSN5_C PF18323.1 KXX76339.1 - 0.38 11.7 3.3 0.31 12.0 1.1 2.0 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain TPR_MLP1_2 PF07926.12 KXX76339.1 - 3.7 7.6 10.5 4.2 7.4 1.3 2.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KXX76339.1 - 3.7 6.8 9.0 4.1 6.7 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MerR-DNA-bind PF09278.11 KXX76339.1 - 6.6 7.4 9.0 3.8 8.1 0.1 3.2 3 0 0 3 3 3 0 MerR, DNA binding COG2 PF06148.11 KXX76339.1 - 7.4 6.7 6.1 5.6 7.1 0.4 3.1 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Pyr_redox_2 PF07992.14 KXX76340.1 - 5e-40 137.6 0.9 5.9e-40 137.3 0.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX76340.1 - 2.8e-11 43.8 1.3 1.9e-07 31.5 0.8 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXX76340.1 - 0.00027 20.2 0.0 0.0074 15.5 0.0 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXX76340.1 - 0.0037 17.3 1.7 2 8.4 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXX76340.1 - 0.026 13.8 0.1 0.62 9.3 0.1 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX76340.1 - 0.2 10.7 0.7 10 5.0 0.0 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein ATPgrasp_YheCD PF14398.6 KXX76341.1 - 0.03 13.6 0.1 0.066 12.5 0.0 1.6 1 1 1 2 2 2 0 YheC/D like ATP-grasp Slp PF03843.13 KXX76341.1 - 0.12 11.8 0.0 1.8 7.9 0.0 2.0 1 1 1 2 2 2 0 Outer membrane lipoprotein Slp family TMF_TATA_bd PF12325.8 KXX76341.1 - 0.16 12.2 0.4 0.26 11.5 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ADH_zinc_N PF00107.26 KXX76343.1 - 5.3e-23 81.4 0.1 9.2e-23 80.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXX76343.1 - 1.1e-19 70.4 0.0 1.8e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXX76343.1 - 1.4e-11 45.6 0.0 2.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Vma12 PF11712.8 KXX76344.1 - 2.6e-44 150.7 0.0 5e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PSDC PF12588.8 KXX76344.1 - 3.4e-35 121.1 0.0 6.7e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase DUF2200 PF09966.9 KXX76344.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) PBP_N PF17093.5 KXX76344.1 - 0.44 10.8 3.2 4.1 7.7 0.1 2.6 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus SYS1 PF09801.9 KXX76345.1 - 5.6e-51 172.5 3.7 6.7e-51 172.2 3.7 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PIP5K PF01504.18 KXX76346.1 - 1.3e-103 346.0 0.1 1.3e-103 346.0 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Amidohydro_1 PF01979.20 KXX76347.1 - 4.2e-28 98.7 0.0 1.5e-27 96.8 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXX76347.1 - 2.2e-13 50.5 0.1 3.8e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family AalphaY_MDB PF04611.12 KXX76347.1 - 0.063 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region XPG_I PF00867.18 KXX76348.1 - 2.6e-31 107.8 2.2 4.2e-31 107.1 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KXX76348.1 - 5e-25 87.9 0.0 5e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KXX76348.1 - 2.9e-05 24.6 0.6 0.00025 21.6 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KXX76348.1 - 0.064 13.9 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain NAD_binding_6 PF08030.12 KXX76349.1 - 5.7e-31 107.8 0.0 1.1e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXX76349.1 - 6.7e-20 71.2 0.8 1.3e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KXX76349.1 - 7.5e-19 68.1 20.1 3.1e-18 66.1 12.1 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component UQ_con PF00179.26 KXX76350.1 - 3e-53 179.2 0.0 3.3e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXX76350.1 - 0.0089 16.3 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXX76350.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 KXX76350.1 - 0.024 14.3 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Helo_like_N PF17111.5 KXX76351.1 - 1.5e-16 60.4 0.4 1.8e-16 60.2 0.4 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins FAA_hydro_N_2 PF18288.1 KXX76351.1 - 0.12 12.8 0.5 17 5.9 0.1 2.7 1 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Tim17 PF02466.19 KXX76353.1 - 1.8e-08 34.8 6.1 3e-08 34.0 6.0 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.29 KXX76354.1 - 1.5e-28 100.1 0.0 4.2e-28 98.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KXX76354.1 - 7.5e-12 45.0 0.0 9.8e-06 25.4 0.0 3.8 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.6 KXX76354.1 - 2.4e-06 27.4 0.3 0.055 13.0 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 KXX76354.1 - 0.00071 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 PUB domain TPR_10 PF13374.6 KXX76355.1 - 1.3e-35 120.3 1.7 1.3e-12 47.1 0.0 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXX76355.1 - 3.6e-25 88.0 0.5 5.5e-08 33.0 0.2 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.22 KXX76355.1 - 7e-09 35.2 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_4 PF07721.14 KXX76355.1 - 4.9e-07 29.8 1.0 0.27 12.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX76355.1 - 9.3e-07 28.5 0.1 0.32 11.1 0.1 4.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXX76355.1 - 1.8e-06 27.6 0.8 4.4 7.7 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX76355.1 - 4.7e-06 26.2 2.9 0.00054 19.4 0.1 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 KXX76355.1 - 5.6e-06 26.9 3.9 0.29 11.8 0.0 5.0 4 1 1 5 5 4 2 Tetratricopeptide repeat NACHT PF05729.12 KXX76355.1 - 0.00075 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.6 KXX76355.1 - 0.00099 19.7 2.9 13 6.9 0.0 5.5 3 1 2 5 5 5 0 Tetratricopeptide repeat AAA_25 PF13481.6 KXX76355.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ses_B PF17046.5 KXX76355.1 - 0.0083 16.1 0.4 0.015 15.2 0.4 1.4 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein AAA_16 PF13191.6 KXX76355.1 - 0.018 15.4 0.1 0.073 13.5 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain TPR_19 PF14559.6 KXX76355.1 - 0.023 15.2 1.5 8.6 7.0 0.0 4.0 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXX76355.1 - 0.033 14.0 0.0 54 3.8 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 KXX76355.1 - 0.11 12.8 0.2 40 4.8 0.1 3.1 3 0 0 3 3 3 0 PPR repeat Acyl-CoA_dh_1 PF00441.24 KXX76356.1 - 8.2e-43 146.2 0.2 1.2e-42 145.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXX76356.1 - 8.3e-22 77.2 0.1 1.6e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXX76356.1 - 5.9e-21 74.4 0.3 1.3e-20 73.3 0.3 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KXX76356.1 - 1.8e-18 67.2 0.0 4.2e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXX76356.1 - 4.2e-09 36.8 0.0 6.8e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MutS_V PF00488.21 KXX76357.1 - 1.7e-83 279.3 0.1 2.8e-83 278.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXX76357.1 - 2.8e-38 132.1 1.1 7.9e-38 130.6 0.8 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KXX76357.1 - 1.5e-20 73.9 0.2 8e-20 71.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KXX76357.1 - 9e-19 67.6 0.5 9e-19 67.6 0.5 3.2 4 0 0 4 4 4 1 MutS family domain IV AAA_27 PF13514.6 KXX76357.1 - 0.059 13.0 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain COX6B PF02297.17 KXX76358.1 - 2.3e-23 82.2 5.1 2.9e-23 81.9 5.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KXX76358.1 - 0.15 12.4 1.9 0.87 9.9 1.9 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 polyprenyl_synt PF00348.17 KXX76359.1 - 3.2e-74 249.2 0.0 6.6e-74 248.2 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KXX76359.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 TPR_12 PF13424.6 KXX76361.1 - 1.9e-87 287.6 26.9 6.2e-20 71.3 1.2 6.6 4 1 4 8 8 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXX76361.1 - 6e-78 254.8 9.1 3.6e-14 52.1 0.1 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXX76361.1 - 1.9e-30 102.6 10.6 0.0001 22.1 0.2 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 KXX76361.1 - 2e-27 93.8 17.9 0.00039 20.1 0.2 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 KXX76361.1 - 5.2e-19 67.2 4.3 0.048 14.1 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXX76361.1 - 5.1e-18 63.7 10.4 0.061 13.5 0.2 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXX76361.1 - 3e-17 63.0 0.0 0.085 13.5 0.0 6.7 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXX76361.1 - 4.2e-16 57.7 12.4 0.02 15.1 0.2 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX76361.1 - 9.3e-15 54.8 10.7 1.8e-10 40.7 5.8 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KXX76361.1 - 5.3e-14 52.5 11.5 0.0033 17.9 0.2 6.1 3 2 3 6 6 6 5 Tetratricopeptide repeat NB-ARC PF00931.22 KXX76361.1 - 5.6e-11 42.1 0.0 1.6e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 KXX76361.1 - 5.3e-09 36.2 5.5 0.079 13.2 0.2 5.8 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXX76361.1 - 1.6e-08 34.7 6.5 1.3 10.0 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXX76361.1 - 4.2e-07 29.5 1.5 0.072 12.3 0.1 5.0 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXX76361.1 - 9.3e-07 28.9 0.0 11 7.0 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 KXX76361.1 - 4e-05 23.6 0.3 68 4.0 0.0 6.3 6 0 0 6 6 5 0 PPR repeat DUF1925 PF09094.11 KXX76361.1 - 0.0089 16.3 8.5 16 5.9 0.1 5.7 1 1 5 6 6 6 0 Domain of unknown function (DUF1925) Mad3_BUB1_I PF08311.12 KXX76361.1 - 0.009 16.0 6.8 96 3.0 0.0 5.7 6 0 0 6 6 5 0 Mad3/BUB1 homology region 1 DUF676 PF05057.14 KXX76361.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_16 PF13191.6 KXX76361.1 - 0.014 15.8 0.1 0.078 13.4 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain TPR_11 PF13414.6 KXX76361.1 - 0.039 13.6 22.7 8.2 6.2 0.7 7.4 8 0 0 8 8 7 0 TPR repeat YjgF_endoribonc PF14588.6 KXX76361.1 - 0.07 13.3 0.2 26 4.9 0.0 3.5 2 1 1 3 3 3 0 YjgF/chorismate_mutase-like, putative endoribonuclease Abhydrolase_6 PF12697.7 KXX76361.1 - 0.09 13.4 1.0 0.65 10.6 0.1 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family TPR_6 PF13174.6 KXX76361.1 - 0.27 12.0 3.9 1.8e+02 3.1 0.0 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXX76361.1 - 2.1 8.4 15.5 1.9 8.6 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF627 PF04781.12 KXX76361.1 - 2.5 8.2 15.5 32 4.6 0.3 6.0 5 1 1 6 6 6 0 Protein of unknown function (DUF627) MIT PF04212.18 KXX76361.1 - 5.5 7.1 13.4 4.1 7.5 0.6 5.2 3 1 2 5 5 5 0 MIT (microtubule interacting and transport) domain DUF4404 PF14357.6 KXX76361.1 - 6.3 7.5 18.6 2.8 8.6 0.4 4.4 2 1 4 6 6 6 0 Domain of unknown function (DUF4404) HARE-HTH PF05066.13 KXX76361.1 - 6.7 7.2 6.3 41 4.7 0.1 3.5 4 0 0 4 4 2 0 HB1, ASXL, restriction endonuclease HTH domain PS_Dcarbxylase PF02666.15 KXX76362.1 - 8.3e-26 90.8 0.0 1.1e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 KXX76362.1 - 0.14 12.1 0.2 16 5.5 0.0 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Acyl-CoA_dh_N PF02771.16 KXX76363.1 - 8.9e-25 87.6 0.1 1.9e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXX76363.1 - 6e-24 85.0 0.3 1.1e-23 84.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXX76363.1 - 1.4e-18 66.9 0.0 2.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXX76363.1 - 1.7e-06 28.3 0.3 3.2e-06 27.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DNA_methylase PF00145.17 KXX76365.1 - 5.2e-34 118.1 0.0 1.1e-25 90.7 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.18 KXX76365.1 - 5.6e-06 26.2 0.0 0.058 13.3 0.0 2.4 2 0 0 2 2 2 2 BAH domain zf-RING_2 PF13639.6 KXX76366.1 - 5.5e-08 33.0 11.8 9.2e-08 32.3 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX76366.1 - 2.1e-06 27.5 7.0 3.3e-06 26.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX76366.1 - 5.2e-06 26.2 12.3 1e-05 25.2 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX76366.1 - 1.2e-05 25.1 8.1 1.9e-05 24.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX76366.1 - 4.7e-05 23.6 10.7 0.00017 21.8 10.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXX76366.1 - 0.1 12.6 4.7 0.21 11.6 4.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger GAGA PF09237.11 KXX76366.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.2 3 0 0 3 3 3 0 GAGA factor zf-ANAPC11 PF12861.7 KXX76366.1 - 0.24 11.5 3.0 0.56 10.3 3.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXX76366.1 - 0.92 9.4 7.0 1.7 8.5 7.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXX76366.1 - 1.7 8.5 7.6 3.9 7.3 7.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 KXX76366.1 - 3.8 7.4 5.8 7 6.5 5.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KXX76366.1 - 7.1 6.7 8.6 12 5.9 8.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Drc1-Sld2 PF11719.8 KXX76367.1 - 1.8e-83 281.6 21.7 5.7e-83 280.0 21.7 1.7 1 1 0 1 1 1 1 DNA replication and checkpoint protein DUF5137 PF17220.3 KXX76367.1 - 0.13 13.1 0.3 0.13 13.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5137) TFIID_20kDa PF03847.13 KXX76368.1 - 4.7e-18 65.5 0.0 8.2e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A ASD2 PF08687.11 KXX76368.1 - 0.29 10.6 8.5 0.55 9.7 0.3 2.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Rpn3_C PF08375.11 KXX76369.1 - 6.2e-26 90.6 1.7 1.8e-25 89.1 1.7 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KXX76369.1 - 2.4e-20 73.0 1.1 9.7e-20 71.0 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 KXX76369.1 - 0.017 15.2 0.1 0.057 13.6 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 KXX76370.1 - 8.3e-08 32.3 8.6 0.0011 19.3 2.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 KXX76370.1 - 5.5e-07 28.9 0.0 0.00078 18.6 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KXX76370.1 - 0.11 13.3 14.1 0.39 11.7 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger FTHFS PF01268.19 KXX76371.1 - 9.1e-256 849.4 0.0 1.2e-255 849.0 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KXX76371.1 - 2.5e-67 225.2 0.7 2.5e-67 225.2 0.7 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KXX76371.1 - 1.2e-38 131.9 0.2 2.7e-38 130.8 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 KXX76371.1 - 0.12 11.9 0.3 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain IF2_N PF04760.15 KXX76371.1 - 0.15 11.9 0.0 24 4.9 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region WD40 PF00400.32 KXX76372.1 - 3.3e-26 91.0 1.9 4.8e-09 36.7 0.1 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX76372.1 - 3.9e-14 52.7 0.0 1.1e-05 25.6 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX76372.1 - 0.00027 19.7 0.0 0.00042 19.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KXX76372.1 - 0.00097 18.3 0.1 0.34 9.9 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region PALB2_WD40 PF16756.5 KXX76372.1 - 0.02 13.8 0.1 5.6 5.8 0.0 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KXX76372.1 - 0.029 13.9 0.2 0.087 12.4 0.2 1.9 1 1 0 1 1 1 0 PQQ-like domain WD40_like PF17005.5 KXX76372.1 - 0.092 12.0 0.0 1.1 8.5 0.0 2.4 2 1 0 3 3 3 0 WD40-like domain DSBA PF01323.20 KXX76373.1 - 1.2e-40 139.4 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXX76373.1 - 0.00012 22.2 0.0 0.00036 20.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KXX76373.1 - 0.00075 19.5 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Fig1 PF12351.8 KXX76374.1 - 1.8e-58 197.6 2.9 2.2e-58 197.3 2.9 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF898 PF05987.13 KXX76374.1 - 8.5e-05 21.8 4.1 0.00011 21.4 4.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Glyco_hydro_47 PF01532.20 KXX76376.1 - 1.9e-51 175.4 0.2 1.9e-51 175.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 KXX76377.1 - 2.9e-125 418.8 0.0 3.6e-125 418.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4588 PF15251.6 KXX76378.1 - 4.1e-07 30.0 0.0 7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 KXX76379.1 - 1.6e-74 250.7 0.2 3.1e-74 249.8 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KXX76379.1 - 2.9e-44 149.7 1.7 8.8e-44 148.2 1.7 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KXX76379.1 - 6.6e-40 136.3 4.1 6.6e-40 136.3 4.1 4.0 5 0 0 5 5 3 1 HAND Helicase_C PF00271.31 KXX76379.1 - 6.1e-19 68.4 0.0 2.8e-18 66.3 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX76379.1 - 6.5e-11 42.5 0.1 6e-10 39.4 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXX76379.1 - 5.1e-07 29.2 0.1 2e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KXX76379.1 - 0.00039 19.7 0.2 0.001 18.3 0.2 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KXX76379.1 - 0.00063 19.6 0.0 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KXX76379.1 - 0.00088 19.4 0.0 0.73 10.1 0.0 3.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain SWI2_SNF2 PF18766.1 KXX76379.1 - 0.0016 18.2 0.0 0.0045 16.7 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 KXX76379.1 - 0.057 13.5 0.1 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Occludin_ELL PF07303.13 KXX76379.1 - 0.081 13.7 3.0 0.32 11.7 3.0 2.1 1 0 0 1 1 1 0 Occludin homology domain DEAD_2 PF06733.15 KXX76379.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 DEAD_2 NYD-SP28_assoc PF14775.6 KXX76379.1 - 0.23 11.6 1.7 0.87 9.7 1.1 2.4 2 0 0 2 2 1 0 Sperm tail C-terminal domain DUF3847 PF12958.7 KXX76379.1 - 2.9 8.1 6.0 1.7 8.8 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Pkinase PF00069.25 KXX76381.1 - 3.1e-64 216.9 0.0 4.4e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76381.1 - 3.4e-49 167.5 0.0 5.6e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX76381.1 - 1e-08 34.9 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KXX76381.1 - 0.0065 15.3 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXX76381.1 - 0.0079 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX76381.1 - 0.047 13.6 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DASH_Spc34 PF08657.10 KXX76382.1 - 1.7e-53 182.0 0.0 1.4e-28 100.4 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KXX76382.1 - 1.1 9.2 8.0 1.5 8.7 8.0 1.2 1 0 0 1 1 1 0 Spc19 WD40 PF00400.32 KXX76384.1 - 3.2e-09 37.3 4.6 0.022 15.6 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX76384.1 - 0.0072 16.6 0.0 14 6.0 0.0 3.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S14 PF00253.21 KXX76385.1 - 1.8e-22 78.8 0.9 3.5e-22 77.9 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e LIAS_N PF16881.5 KXX76386.1 - 4.4e-17 62.5 0.0 8.8e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KXX76386.1 - 7.8e-15 55.6 0.0 1.2e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily RCC1 PF00415.18 KXX76389.1 - 1.4e-59 198.5 7.7 1.3e-12 48.1 0.0 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXX76389.1 - 3.8e-35 119.0 20.0 2.4e-09 36.7 0.6 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat QRPTase_C PF01729.19 KXX76390.1 - 7.9e-54 181.9 0.0 9.6e-54 181.7 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KXX76390.1 - 2e-19 69.4 0.0 5.1e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Synaptobrevin PF00957.21 KXX76391.1 - 3.4e-32 110.1 0.4 4.2e-32 109.8 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin Duffy_binding PF05424.11 KXX76391.1 - 0.054 13.5 0.1 0.067 13.2 0.1 1.1 1 0 0 1 1 1 0 Duffy binding domain MCU PF04678.13 KXX76391.1 - 0.086 12.9 0.0 0.096 12.8 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter NAT PF04768.13 KXX76392.1 - 1e-51 175.0 0.1 1.8e-51 174.1 0.1 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KXX76392.1 - 1.3e-34 119.8 0.2 8.6e-34 117.2 0.1 2.0 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KXX76392.1 - 1.5e-31 109.4 0.0 4.1e-31 107.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KXX76392.1 - 0.084 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_3 PF01596.17 KXX76392.1 - 0.18 11.0 0.1 0.83 8.8 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase Semialdhyde_dhC PF02774.18 KXX76393.1 - 1.3e-40 139.4 0.0 2e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KXX76393.1 - 2.5e-14 53.7 0.0 1.3e-13 51.4 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.25 KXX76395.1 - 8.3e-24 84.4 0.0 2.7e-12 46.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76395.1 - 6.6e-10 38.7 0.3 0.00041 19.7 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXX76395.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXX76395.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP PF00620.27 KXX76396.1 - 2.1e-49 167.2 0.1 7.1e-49 165.5 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KXX76396.1 - 7.2e-15 55.0 0.4 7.2e-15 55.0 0.4 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2293 PF10056.9 KXX76396.1 - 0.16 12.2 1.0 0.4 10.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) Com_YlbF PF06133.11 KXX76396.1 - 1.2 9.8 7.3 0.95 10.1 2.5 2.9 2 1 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DUF4407 PF14362.6 KXX76396.1 - 3.6 6.9 12.0 12 5.2 12.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 KXX76397.1 - 7.5e-20 70.5 0.0 1.4e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KXX76397.1 - 0.027 14.3 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 KXX76397.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Zn_clus PF00172.18 KXX76398.1 - 6.6e-05 22.9 11.1 0.00011 22.2 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTC PF01137.21 KXX76399.1 - 1.7e-46 158.2 0.0 2.7e-46 157.5 0.0 1.3 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase ThiF PF00899.21 KXX76401.1 - 6.2e-39 133.8 0.0 1e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KXX76401.1 - 0.00016 21.9 0.1 2.2 8.5 0.2 3.2 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KXX76401.1 - 0.066 13.6 0.0 0.2 12.1 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KXX76401.1 - 0.072 12.7 0.1 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KXX76401.1 - 0.09 13.0 2.3 0.12 12.7 0.0 2.4 4 0 0 4 4 4 0 TrkA-N domain CAP_N PF01213.19 KXX76402.1 - 0.64 9.4 14.7 0.047 13.2 9.3 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal HTH_Tnp_Tc5 PF03221.16 KXX76403.1 - 3.8e-10 39.7 0.0 1.3e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KXX76403.1 - 6.6e-07 28.9 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 KXX76403.1 - 0.0034 17.3 0.1 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_Tnp_4 PF13613.6 KXX76403.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.7 KXX76403.1 - 0.043 13.7 0.1 0.38 10.7 0.0 2.5 3 0 0 3 3 3 0 MarR family LacI PF00356.21 KXX76403.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_Crp_2 PF13545.6 KXX76403.1 - 0.2 11.6 0.7 1 9.4 0.0 2.4 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain MMR_HSR1_Xtn PF16897.5 KXX76404.1 - 4.5e-41 139.2 1.5 2.4e-40 136.8 0.7 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KXX76404.1 - 4.9e-22 77.7 0.0 9.9e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KXX76404.1 - 1.2e-21 76.9 0.0 7.7e-21 74.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX76404.1 - 8.5e-10 38.4 0.0 3.8e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXX76404.1 - 0.00015 21.9 0.1 0.047 13.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KXX76404.1 - 0.00016 21.2 0.1 3.5 7.1 0.0 4.0 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXX76404.1 - 0.006 15.6 0.3 0.027 13.4 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KXX76404.1 - 0.069 13.1 0.4 6.8 6.6 0.0 2.8 2 1 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 KXX76404.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 KXX76404.1 - 0.09 13.0 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXX76404.1 - 0.092 13.0 0.1 0.72 10.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain DUF211 PF02680.14 KXX76404.1 - 0.11 12.7 0.7 0.45 10.7 0.3 2.3 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 PXA PF02194.15 KXX76405.1 - 6.3e-49 166.4 1.5 8.5e-49 166.0 1.5 1.2 1 0 0 1 1 1 1 PXA domain Steroid_dh PF02544.16 KXX76406.1 - 2.5e-11 43.8 1.4 8.6e-11 42.0 1.4 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ATP-synt_DE_N PF02823.16 KXX76407.1 - 1.2e-17 63.5 0.1 1.9e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ank_2 PF12796.7 KXX76408.1 - 1.4e-20 73.6 0.0 1.9e-13 50.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX76408.1 - 1.2e-13 51.2 0.0 0.00029 21.3 0.1 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX76408.1 - 5.8e-13 48.8 2.5 1.6e-06 28.2 0.4 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX76408.1 - 6.6e-11 41.5 0.2 0.0028 18.0 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXX76408.1 - 1e-08 35.3 3.3 0.0032 17.8 0.3 4.4 4 0 0 4 4 4 2 Ankyrin repeat 2OG-FeII_Oxy_2 PF13532.6 KXX76409.1 - 4.6e-13 49.8 0.0 1.4e-11 45.0 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2457 PF10446.9 KXX76410.1 - 1.4e-173 578.4 27.3 1.4e-173 578.4 27.3 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 KXX76410.1 - 4.5 5.4 20.0 7 4.7 20.0 1.2 1 0 0 1 1 1 0 Nop14-like family Arf PF00025.21 KXX76411.1 - 2.9e-66 222.2 0.0 3.3e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXX76411.1 - 1.2e-11 44.5 0.0 5e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KXX76411.1 - 2.2e-07 31.1 0.0 7.4e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXX76411.1 - 2.8e-07 30.1 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXX76411.1 - 5.4e-07 29.7 0.0 7.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXX76411.1 - 6.3e-07 29.1 0.0 8.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXX76411.1 - 2.7e-05 23.7 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXX76411.1 - 0.0027 17.3 0.0 0.11 12.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KXX76411.1 - 0.045 13.3 0.0 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Esterase_phd PF10503.9 KXX76412.1 - 0.011 15.2 0.6 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF3336 PF11815.8 KXX76413.1 - 4.7e-49 165.6 0.3 7.6e-49 165.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXX76413.1 - 1.7e-17 64.3 0.1 1.1e-16 61.6 0.0 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase DUF4337 PF14235.6 KXX76413.1 - 9.1 6.4 5.6 1.2 9.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) zf-Mss51 PF13824.6 KXX76414.1 - 2.9e-29 100.9 8.1 6e-29 99.9 8.1 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KXX76414.1 - 0.0086 16.2 3.0 0.0086 16.2 3.0 2.0 2 0 0 2 2 2 1 MYND finger MMS1_N PF10433.9 KXX76415.1 - 7.3e-156 519.6 0.0 8.5e-155 516.1 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXX76415.1 - 2.2e-101 339.4 0.0 6.6e-101 337.8 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region UBM PF14377.6 KXX76415.1 - 0.28 10.7 2.4 0.61 9.6 0.5 2.4 2 0 0 2 2 2 0 Ubiquitin binding region UBA_4 PF14555.6 KXX76416.1 - 0.0064 16.3 0.3 0.015 15.1 0.2 1.6 2 0 0 2 2 2 1 UBA-like domain LysM PF01476.20 KXX76416.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 LysM domain CCDC53 PF10152.9 KXX76416.1 - 0.085 13.3 0.3 0.12 12.8 0.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Prok-RING_4 PF14447.6 KXX76416.1 - 0.25 11.2 10.8 0.67 9.9 10.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXX76416.1 - 2.1 8.7 12.7 6.7 7.1 12.7 1.9 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KXX76416.1 - 2.5 8.0 11.5 0.67 9.9 4.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX76416.1 - 8.8 6.4 12.8 28 4.8 12.9 1.9 1 1 0 1 1 1 0 zinc-RING finger domain TPR_12 PF13424.6 KXX76417.1 - 1.6e-32 111.6 13.1 1e-19 70.6 2.8 4.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXX76417.1 - 5.9e-32 108.6 10.8 4.7e-12 45.4 0.4 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXX76417.1 - 4.1e-17 60.9 11.9 9.8e-06 25.3 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX76417.1 - 9.3e-17 60.1 13.0 2.4e-06 27.1 0.3 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX76417.1 - 3.6e-13 48.6 12.3 0.00033 20.6 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX76417.1 - 6.4e-13 47.7 13.3 0.00016 21.5 0.3 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_4 PF07721.14 KXX76417.1 - 3e-12 45.9 0.9 0.045 14.4 0.0 4.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXX76417.1 - 1.7e-07 31.5 11.7 0.15 13.0 0.1 5.2 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX76417.1 - 4e-07 30.6 15.8 5.8e-05 23.7 6.3 4.2 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX76417.1 - 1.2e-06 29.0 3.5 0.00061 20.2 0.4 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX76417.1 - 1.6e-06 27.7 0.2 3.3e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 MalT-like TPR region AAA_16 PF13191.6 KXX76417.1 - 9.5e-06 26.1 0.0 6e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_17 PF13431.6 KXX76417.1 - 1.1e-05 25.5 11.1 0.75 10.3 0.1 5.3 5 1 0 5 5 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 KXX76417.1 - 1.7e-05 24.1 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Abhydrolase_6 PF12697.7 KXX76417.1 - 3.6e-05 24.5 7.1 0.00081 20.1 1.3 2.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXX76417.1 - 0.00014 21.4 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) ATPase_2 PF01637.18 KXX76417.1 - 0.0053 16.7 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PGAP1 PF07819.13 KXX76417.1 - 0.012 15.3 0.1 0.027 14.2 0.0 1.6 2 0 0 2 2 1 0 PGAP1-like protein ANAPC3 PF12895.7 KXX76417.1 - 0.017 15.3 1.0 0.73 10.1 0.1 3.1 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4810 PF16068.5 KXX76417.1 - 0.018 15.6 3.7 9.5 6.9 0.0 3.9 4 0 0 4 4 3 0 Domain of unknown function (DUF4810) PPR PF01535.20 KXX76417.1 - 0.03 14.6 3.4 45 4.6 0.0 4.6 5 0 0 5 5 5 0 PPR repeat SRP68 PF16969.5 KXX76417.1 - 0.039 13.0 0.2 4.6 6.1 0.0 2.9 1 1 2 3 3 3 0 RNA-binding signal recognition particle 68 YjeF_N PF03853.15 KXX76417.1 - 0.12 12.3 0.1 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus TPR_11 PF13414.6 KXX76417.1 - 0.2 11.4 15.5 2 8.2 0.8 3.6 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 KXX76417.1 - 0.38 11.5 11.8 6.8 7.6 0.5 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NDUF_B12 PF08122.12 KXX76419.1 - 9.6 6.3 6.0 21 5.3 0.1 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Carb_bind PF10645.9 KXX76420.1 - 3.8e-16 59.0 11.3 3.8e-16 59.0 11.3 2.2 2 0 0 2 2 2 1 Carbohydrate binding Acetyltransf_10 PF13673.7 KXX76421.1 - 5.3e-07 29.6 0.0 7.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX76421.1 - 1.7e-05 25.0 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX76421.1 - 4.1e-05 23.9 0.0 7.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX76421.1 - 0.041 13.9 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF1992 PF09350.10 KXX76422.1 - 1.8e-21 76.0 0.3 4.5e-21 74.8 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) AMP-binding PF00501.28 KXX76423.1 - 5.9e-78 262.3 0.0 7.7e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX76423.1 - 5.6e-16 59.3 0.2 5.3e-15 56.2 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KXX76424.1 - 1e-39 136.5 27.4 3.1e-39 134.9 25.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX76424.1 - 4.9e-10 38.9 20.8 9.8e-10 37.9 20.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3671 PF12420.8 KXX76424.1 - 0.39 10.8 8.1 2.4 8.3 0.4 4.3 3 3 1 4 4 4 0 Protein of unknown function Ank_4 PF13637.6 KXX76426.1 - 1.2e-12 48.0 0.0 3.9e-06 27.3 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX76426.1 - 6.5e-11 42.7 0.0 1.3e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXX76426.1 - 1.9e-08 34.4 0.0 2.9e-07 30.6 0.0 2.7 3 0 0 3 3 2 1 Ankyrin repeat Ank_3 PF13606.6 KXX76426.1 - 2e-08 33.8 0.0 1.7e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat MMR_HSR1 PF01926.23 KXX76426.1 - 4e-08 33.3 0.4 1.8e-07 31.2 0.0 2.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase Ank_5 PF13857.6 KXX76426.1 - 1.5e-06 28.4 0.0 0.00026 21.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RsgA_GTPase PF03193.16 KXX76426.1 - 6.7e-06 26.1 0.1 2.3e-05 24.4 0.0 2.0 2 0 0 2 2 1 1 RsgA GTPase Dynamin_N PF00350.23 KXX76426.1 - 1.2e-05 25.5 2.3 0.051 13.6 0.1 3.2 2 1 1 3 3 3 2 Dynamin family AAA_18 PF13238.6 KXX76426.1 - 0.00042 20.9 0.0 0.0017 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 KXX76426.1 - 0.0005 19.5 0.5 0.0017 17.7 0.0 2.1 3 0 0 3 3 3 1 AIG1 family IIGP PF05049.13 KXX76426.1 - 0.00082 18.5 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KXX76426.1 - 0.0029 17.0 0.3 0.005 16.2 0.0 1.5 2 0 0 2 2 1 1 Septin AAA_33 PF13671.6 KXX76426.1 - 0.0041 17.3 0.4 0.072 13.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 KXX76426.1 - 0.0075 16.7 0.0 0.032 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 KXX76426.1 - 0.0076 16.1 0.1 0.059 13.1 0.0 2.3 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KXX76426.1 - 0.0083 16.4 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXX76426.1 - 0.0089 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 KXX76426.1 - 0.01 15.9 1.9 0.037 14.1 0.0 2.4 3 0 0 3 3 3 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KXX76426.1 - 0.011 15.1 0.0 0.18 11.1 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family SRP54 PF00448.22 KXX76426.1 - 0.021 14.5 0.2 0.11 12.1 0.0 2.3 2 1 1 3 3 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KXX76426.1 - 0.03 14.8 0.9 0.18 12.3 0.0 2.4 2 1 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 KXX76426.1 - 0.046 12.9 0.2 0.17 11.0 0.0 2.0 3 0 0 3 3 2 0 NB-ARC domain AAA_23 PF13476.6 KXX76426.1 - 0.051 14.1 0.7 3.2 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain WXG100 PF06013.12 KXX76426.1 - 0.054 13.7 1.3 0.35 11.1 2.0 2.0 2 0 0 2 2 1 0 Proteins of 100 residues with WXG Viral_helicase1 PF01443.18 KXX76426.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KXX76426.1 - 0.058 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KXX76426.1 - 0.072 12.4 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF3782 PF12644.7 KXX76426.1 - 0.12 12.6 0.6 0.48 10.6 0.4 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF3782) AAA_7 PF12775.7 KXX76426.1 - 0.14 11.6 0.1 0.48 9.9 0.0 1.9 2 0 0 2 2 1 0 P-loop containing dynein motor region Spore_IV_A PF09547.10 KXX76426.1 - 0.15 11.0 0.4 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) MerR-DNA-bind PF09278.11 KXX76426.1 - 0.17 12.5 1.8 0.57 10.8 1.8 1.9 1 0 0 1 1 1 0 MerR, DNA binding G-alpha PF00503.20 KXX76426.1 - 0.23 10.6 0.1 0.87 8.7 0.0 1.9 2 1 0 2 2 2 0 G-protein alpha subunit DivIC PF04977.15 KXX76426.1 - 0.34 10.7 2.9 0.71 9.7 2.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Ank_2 PF12796.7 KXX76427.1 - 9.2e-44 147.9 6.5 1e-14 54.9 0.7 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX76427.1 - 1.4e-35 120.9 10.4 1.6e-09 37.8 0.3 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX76427.1 - 2e-30 104.8 2.9 2e-08 34.6 0.1 5.3 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX76427.1 - 1.3e-29 98.9 5.9 6.1e-05 23.1 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KXX76427.1 - 3e-24 84.3 18.1 0.00018 21.8 0.4 7.8 7 1 0 7 7 7 6 Ankyrin repeat MMR_HSR1 PF01926.23 KXX76428.1 - 3.8e-07 30.2 0.0 0.031 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX76428.1 - 7.7e-05 22.7 0.0 0.00032 20.6 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXX76428.1 - 7.7e-05 23.1 0.6 0.0024 18.3 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain AIG1 PF04548.16 KXX76428.1 - 0.00038 19.8 0.0 0.16 11.3 0.0 2.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KXX76428.1 - 0.0046 17.0 2.7 0.53 10.3 0.0 2.8 3 0 0 3 3 2 2 Dynamin family T2SSE PF00437.20 KXX76428.1 - 0.0083 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXX76428.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 KXX76428.1 - 0.022 14.1 0.1 0.11 11.8 0.1 2.1 1 1 0 1 1 1 0 Septin IIGP PF05049.13 KXX76428.1 - 0.03 13.4 0.0 0.076 12.1 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TniB PF05621.11 KXX76428.1 - 0.033 13.6 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KXX76428.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KXX76428.1 - 0.059 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KXX76428.1 - 0.088 13.3 0.2 0.42 11.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Roc PF08477.13 KXX76428.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF4404 PF14357.6 KXX76428.1 - 0.2 12.3 1.0 1.4 9.6 1.0 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) AAA_23 PF13476.6 KXX76428.1 - 0.59 10.6 2.8 0.81 10.1 0.0 2.4 2 1 0 2 2 1 0 AAA domain TauD PF02668.16 KXX76429.1 - 9.6e-32 110.8 0.0 1.3e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXX76429.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 CsiD Zn_clus PF00172.18 KXX76430.1 - 0.13 12.4 6.9 0.29 11.3 6.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX76431.1 - 1.2e-14 54.1 0.0 1.8e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cons_hypoth698 PF03601.14 KXX76431.1 - 0.013 14.4 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 F-box-like PF12937.7 KXX76433.1 - 0.00099 19.0 1.7 0.0023 17.8 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX76433.1 - 0.085 12.8 0.8 0.23 11.4 0.8 1.7 1 0 0 1 1 1 0 F-box domain Pkinase_Tyr PF07714.17 KXX76434.1 - 6.8e-07 28.8 0.0 2.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXX76434.1 - 4.6e-06 26.2 0.0 1.8e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF1996 PF09362.10 KXX76436.1 - 2.1e-83 279.9 1.5 2.5e-83 279.7 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gal_mutarotas_2 PF13802.6 KXX76436.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Galactose mutarotase-like HET PF06985.11 KXX76437.1 - 7.9e-06 26.3 0.1 0.00026 21.4 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MgsA_C PF12002.8 KXX76438.1 - 6.3e-61 205.2 0.1 1.8e-60 203.7 0.0 1.7 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KXX76438.1 - 7.1e-24 84.0 0.1 1.6e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KXX76438.1 - 1e-12 48.6 0.0 2.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX76438.1 - 4.9e-09 36.1 0.0 9.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KXX76438.1 - 9.2e-07 28.7 0.1 3.8e-05 23.4 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KXX76438.1 - 1.1e-05 25.8 5.7 0.0034 17.8 0.1 3.3 1 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXX76438.1 - 8.8e-05 22.8 0.3 0.00047 20.4 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX76438.1 - 0.00017 21.6 0.3 0.013 15.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXX76438.1 - 0.00036 20.6 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXX76438.1 - 0.00038 19.9 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXX76438.1 - 0.0051 16.7 0.0 0.1 12.5 0.0 2.6 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXX76438.1 - 0.0053 15.9 0.0 0.012 14.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KXX76438.1 - 0.0073 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain ResIII PF04851.15 KXX76438.1 - 0.014 15.4 0.2 0.9 9.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXX76438.1 - 0.016 15.5 0.1 0.19 12.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain SKI PF01202.22 KXX76438.1 - 0.027 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 KXX76438.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXX76438.1 - 0.077 13.2 0.7 0.22 11.7 0.7 1.8 1 1 0 1 1 1 0 AAA domain zf-WRNIP1_ubi PF18279.1 KXX76438.1 - 0.084 13.6 0.6 0.2 12.3 0.1 2.0 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain TniB PF05621.11 KXX76438.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Cytidylate_kin PF02224.18 KXX76438.1 - 0.13 12.0 0.2 0.66 9.7 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 KXX76438.1 - 0.13 12.8 0.1 0.54 10.8 0.1 2.0 2 0 0 2 2 2 0 ABC transporter CPT PF07931.12 KXX76438.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Pmp3 PF01679.17 KXX76439.1 - 1.1e-18 67.2 7.9 1.4e-18 66.8 7.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator IPK PF03770.16 KXX76440.1 - 1.5e-50 171.8 0.0 2.1e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.10 KXX76441.1 - 3.1e-46 158.3 0.3 5.9e-24 85.0 0.0 2.9 2 1 0 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PQ-loop PF04193.14 KXX76442.1 - 7e-41 137.8 9.1 7.7e-21 73.6 1.9 2.7 2 0 0 2 2 2 2 PQ loop repeat HTH_Bact PF18768.1 KXX76442.1 - 0.15 11.7 0.9 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain CLP1_P PF16575.5 KXX76443.1 - 5.5e-32 111.1 0.0 1.4e-31 109.8 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KXX76443.1 - 1.1e-25 89.6 0.0 1.7e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KXX76443.1 - 2.3e-24 86.1 0.0 4.4e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CbiA PF01656.23 KXX76443.1 - 0.0024 17.9 0.0 0.005 16.9 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KXX76443.1 - 0.017 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXX76443.1 - 0.034 14.2 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KXX76443.1 - 0.039 14.0 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXX76443.1 - 0.083 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 KXX76443.1 - 0.093 12.2 0.1 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_18 PF13238.6 KXX76443.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXX76443.1 - 0.15 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX76443.1 - 0.16 12.4 0.1 0.39 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain Velvet PF11754.8 KXX76444.1 - 4.2e-53 180.8 0.5 1.2e-34 120.4 0.0 3.8 2 2 1 3 3 3 2 Velvet factor Pex14_N PF04695.13 KXX76445.1 - 0.59 10.8 3.7 1.5 9.4 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.16 KXX76446.1 - 1.2e-18 67.2 41.5 1.2e-18 67.2 41.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXX76446.1 - 4.1e-09 35.5 26.9 2e-07 30.0 11.5 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein Toxin_GhoT_OrtT PF10753.9 KXX76446.1 - 0.18 12.1 0.1 0.18 12.1 0.1 3.0 2 1 1 3 3 3 0 Toxin GhoT_OrtT ECH_1 PF00378.20 KXX76447.1 - 8e-22 77.8 0.1 2.4e-21 76.2 0.1 1.7 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX76447.1 - 9.9e-13 48.3 0.0 1.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXX76448.1 - 8e-22 77.8 0.1 2.4e-21 76.2 0.1 1.7 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX76448.1 - 9.9e-13 48.3 0.0 1.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 KXX76449.1 - 1.2e-18 67.2 41.5 1.2e-18 67.2 41.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXX76449.1 - 4.1e-09 35.5 26.9 2e-07 30.0 11.5 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein Toxin_GhoT_OrtT PF10753.9 KXX76449.1 - 0.18 12.1 0.1 0.18 12.1 0.1 3.0 2 1 1 3 3 3 0 Toxin GhoT_OrtT Vps51 PF08700.11 KXX76450.1 - 1.9e-13 50.3 0.0 5.2e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 REV1_C PF16727.5 KXX76450.1 - 0.17 12.3 1.4 3.8 8.0 0.6 3.2 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Death PF00531.22 KXX76450.1 - 0.36 11.0 0.0 0.36 11.0 0.0 3.4 5 1 0 5 5 5 0 Death domain Vps51 PF08700.11 KXX76451.1 - 1.9e-13 50.3 0.0 5.2e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 REV1_C PF16727.5 KXX76451.1 - 0.17 12.3 1.4 3.8 8.0 0.6 3.2 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Death PF00531.22 KXX76451.1 - 0.36 11.0 0.0 0.36 11.0 0.0 3.4 5 1 0 5 5 5 0 Death domain SPC12 PF06645.13 KXX76452.1 - 0.041 14.0 5.2 0.079 13.1 5.2 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MCM_bind PF09739.9 KXX76453.1 - 0.17 10.3 0.4 0.22 9.9 0.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PQ-loop PF04193.14 KXX76454.1 - 7e-41 137.8 9.1 7.7e-21 73.6 1.9 2.7 2 0 0 2 2 2 2 PQ loop repeat HTH_Bact PF18768.1 KXX76454.1 - 0.15 11.7 0.9 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain Cullin PF00888.22 KXX76455.1 - 7e-167 556.7 0.0 8.3e-167 556.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXX76455.1 - 1.4e-24 85.8 0.1 3.2e-24 84.7 0.1 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain U1snRNP70_N PF12220.8 KXX76456.1 - 7.8e-27 93.8 3.8 1.7e-26 92.7 3.8 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KXX76456.1 - 7e-16 57.8 0.1 2.7e-15 56.0 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX76456.1 - 7.7e-05 22.7 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 KXX76457.1 - 3.4e-15 55.7 0.0 5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 KXX76458.1 - 1.3e-92 309.5 0.5 1.5e-92 309.4 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase U3_snoRNA_assoc PF08297.11 KXX76459.1 - 1.8e-14 54.2 2.3 1.8e-14 54.2 2.3 4.4 3 2 0 3 3 3 1 U3 snoRNA associated CDC45 PF02724.14 KXX76459.1 - 9.8 4.3 23.7 26 2.9 23.7 1.8 1 1 0 1 1 1 0 CDC45-like protein TPR_2 PF07719.17 KXX76460.1 - 2.4e-06 27.2 1.3 0.023 14.8 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX76460.1 - 9.4e-06 26.2 10.3 0.0089 16.7 3.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX76460.1 - 0.00052 19.7 0.1 0.074 12.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX76460.1 - 0.0078 16.2 1.0 2 8.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX76460.1 - 0.032 14.5 3.2 0.39 11.0 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX76460.1 - 0.29 11.9 4.9 2.3 9.0 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX76460.1 - 0.33 11.9 12.5 0.22 12.4 1.3 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXX76460.1 - 1.3 9.2 7.0 1.2 9.3 1.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PTS_2-RNA PF01885.16 KXX76462.1 - 6.6e-65 218.5 0.0 7.9e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family LRR_6 PF13516.6 KXX76463.1 - 1.6e-09 37.1 0.1 0.026 14.6 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.7 KXX76463.1 - 1.4e-08 34.5 0.1 5.1e-08 32.7 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX76463.1 - 2.4e-05 24.1 0.2 7.5e-05 22.5 0.2 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KXX76463.1 - 0.00012 22.4 5.0 10 6.7 0.0 5.4 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) DUF5308 PF17233.2 KXX76463.1 - 0.0015 18.8 3.4 0.0048 17.1 3.4 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5308) LRR_1 PF00560.33 KXX76463.1 - 0.0074 16.7 7.2 1.4 9.7 0.0 5.5 7 0 0 7 7 7 1 Leucine Rich Repeat Nup188_C PF18378.1 KXX76463.1 - 0.048 12.5 0.0 1.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore protein NUP188 C-terminal domain GRP PF07172.11 KXX76463.1 - 2.1 9.1 12.1 3.9 8.2 12.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family baeRF_family10 PF18854.1 KXX76463.1 - 4.9 7.4 7.3 0.88 9.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Pkinase PF00069.25 KXX76464.1 - 1.9e-57 194.7 0.0 2.6e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76464.1 - 1.5e-19 70.3 0.0 2.3e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX76464.1 - 4.7e-07 29.4 0.0 8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXX76464.1 - 5.5e-06 25.9 0.1 9.7e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX76464.1 - 5.3e-05 23.3 0.4 0.027 14.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXX76464.1 - 0.0034 16.4 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXX76464.1 - 0.0095 15.6 0.2 0.022 14.4 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KXX76464.1 - 0.032 13.0 0.0 0.064 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase UAA PF08449.11 KXX76465.1 - 6.9e-42 143.7 8.9 1.3e-41 142.8 8.9 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXX76465.1 - 1.8e-08 34.7 26.8 7.1e-05 23.0 9.3 3.8 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 KXX76465.1 - 2.2e-06 27.0 2.9 0.0091 15.2 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 KXX76465.1 - 0.00015 21.2 3.0 0.12 11.7 0.1 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 KXX76465.1 - 0.013 14.4 2.8 1.8 7.4 0.1 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like PsaX PF08078.12 KXX76465.1 - 0.032 14.2 1.5 0.3 11.1 0.2 2.9 2 0 0 2 2 2 0 PsaX family DUF1206 PF06724.11 KXX76465.1 - 0.11 12.7 4.7 0.17 12.0 2.2 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DSPc PF00782.20 KXX76467.1 - 4.7e-24 84.7 0.0 9.1e-21 74.1 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXX76467.1 - 0.0029 17.2 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KXX76467.1 - 0.043 14.1 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain KH_1 PF00013.29 KXX76468.1 - 4.1e-41 138.6 10.3 1.3e-16 60.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXX76468.1 - 4.8e-10 39.1 9.0 0.0097 15.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXX76468.1 - 4.1e-09 36.2 3.7 0.014 15.2 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KXX76468.1 - 4.7e-05 23.4 5.2 0.23 11.5 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KXX76468.1 - 0.026 14.5 0.0 11 6.1 0.0 2.8 3 0 0 3 3 3 0 KH-like RNA-binding domain zinc_ribbon_16 PF17034.5 KXX76469.1 - 8e-18 64.8 10.9 1.7e-17 63.8 9.3 2.1 1 1 1 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KXX76469.1 - 3.2e-06 26.7 8.4 1.1e-05 24.9 4.6 2.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KXX76469.1 - 0.29 11.4 5.8 1.2 9.5 5.8 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXX76469.1 - 3.1 7.8 8.1 3.5 7.7 4.3 2.5 2 0 0 2 2 2 0 zinc-RING finger domain Efg1 PF10153.9 KXX76470.1 - 1.2e-33 115.8 10.0 1.2e-33 115.8 10.0 2.3 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF4522 PF15022.6 KXX76470.1 - 0.18 12.1 4.4 0.86 9.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4522) Vir_act_alpha_C PF10400.9 KXX76470.1 - 0.45 11.2 6.5 19 6.0 4.2 2.6 2 1 0 2 2 2 0 Virulence activator alpha C-term C1_2 PF03107.16 KXX76471.1 - 1.3 9.4 11.0 2.2 8.7 11.0 1.3 1 0 0 1 1 1 0 C1 domain zf-C2H2 PF00096.26 KXX76472.1 - 8.1e-09 35.5 20.6 3.6e-06 27.1 3.7 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX76472.1 - 9e-06 26.1 13.1 4.2e-05 24.0 2.0 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXX76472.1 - 1.5e-05 24.8 5.4 0.0017 18.3 1.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXX76472.1 - 1.6e-05 25.1 8.9 4e-05 23.8 3.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXX76472.1 - 0.00056 20.1 1.1 0.00056 20.1 1.1 2.9 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX76472.1 - 0.026 14.9 2.3 0.23 11.9 0.7 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KXX76472.1 - 0.038 14.6 0.6 0.038 14.6 0.6 3.4 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KXX76472.1 - 0.075 13.7 3.5 0.18 12.5 3.5 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger NTS_2 PF15448.6 KXX76472.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein DUF629 PF04780.12 KXX76472.1 - 0.63 8.5 5.9 0.41 9.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_aberr PF17017.5 KXX76472.1 - 1.3 9.2 4.3 3.2 7.9 4.3 1.6 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2HE PF16278.5 KXX76472.1 - 5 7.7 7.3 6.6 7.3 6.1 1.9 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KXX76472.1 - 5.4 7.4 10.7 3 8.2 6.3 2.8 3 1 0 3 3 2 0 C2H2 type zinc-finger (2 copies) STE3 PF02076.15 KXX76474.1 - 1.9e-63 214.4 16.2 2.4e-63 214.0 16.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor SpoIIM PF01944.17 KXX76474.1 - 0.00057 20.0 2.5 0.00057 20.0 2.5 2.3 2 0 0 2 2 2 1 Stage II sporulation protein M DUF3169 PF11368.8 KXX76474.1 - 0.0067 16.0 0.2 0.0067 16.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) DUF1772 PF08592.11 KXX76474.1 - 0.14 12.4 2.9 0.3 11.4 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) 7tm_1 PF00001.21 KXX76474.1 - 0.45 9.8 13.7 0.3 10.4 11.7 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SSB PF00436.25 KXX76475.1 - 1.7e-18 66.5 0.0 2.1e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Rad21_Rec8 PF04824.16 KXX76475.1 - 0.2 10.9 1.1 0.8 9.0 0.9 2.0 2 0 0 2 2 2 0 Conserved region of Rad21 / Rec8 like protein GIDA PF01134.22 KXX76476.1 - 1.1e-155 518.6 0.0 1.3e-155 518.4 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KXX76476.1 - 2.2e-30 106.5 0.5 3.2e-30 105.9 0.5 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KXX76476.1 - 5.5e-06 26.0 4.1 5.7e-06 25.9 3.1 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX76476.1 - 5.7e-06 25.8 0.3 1.2e-05 24.7 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXX76476.1 - 0.00098 18.5 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXX76476.1 - 0.0036 16.1 1.0 0.095 11.4 0.9 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KXX76476.1 - 0.0059 15.7 8.5 0.0059 15.7 5.9 2.2 2 1 1 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KXX76476.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Adap_comp_sub PF00928.21 KXX76477.1 - 5.2e-85 285.0 0.0 6.6e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXX76477.1 - 3.5e-05 23.7 0.2 6.3e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 KXX76477.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Esterase PF00756.20 KXX76479.1 - 0.1 12.2 0.7 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative esterase ketoacyl-synt PF00109.26 KXX76480.1 - 3.1e-63 213.7 1.1 1.5e-62 211.5 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX76480.1 - 8e-57 192.0 1.2 1.9e-56 190.8 1.2 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXX76480.1 - 2.5e-49 168.1 0.4 6.8e-49 166.7 0.0 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX76480.1 - 1.1e-47 163.1 0.2 2.5e-47 161.9 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX76480.1 - 2.5e-38 130.7 0.2 7.3e-38 129.2 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXX76480.1 - 1.1e-17 64.4 0.0 3.1e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXX76480.1 - 2.5e-13 50.0 0.4 2.5e-13 50.0 0.4 2.2 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KXX76480.1 - 5.5e-11 43.1 0.0 2.3e-10 41.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXX76480.1 - 3.8e-10 39.7 0.9 1.1e-09 38.2 0.9 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 KXX76480.1 - 1.1e-09 38.9 0.3 4.2e-08 33.7 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX76480.1 - 1.5e-08 35.2 0.6 1.1e-06 29.3 0.0 3.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX76480.1 - 1.5e-08 34.6 0.0 4.1e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX76480.1 - 1.5e-06 28.1 0.1 1.2e-05 25.1 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXX76480.1 - 6.1e-05 23.3 0.6 0.00023 21.5 0.2 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 KXX76480.1 - 0.0018 17.8 0.1 0.0089 15.5 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX76480.1 - 0.0093 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KXX76480.1 - 0.011 15.8 0.2 0.011 15.8 0.2 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PCMT PF01135.19 KXX76480.1 - 0.12 12.1 0.0 0.52 10.0 0.0 2.1 2 0 0 2 2 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Shikimate_DH PF01488.20 KXX76480.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KXX76480.1 - 0.19 11.2 0.4 0.53 9.8 0.4 1.7 1 0 0 1 1 1 0 NmrA-like family Transferase PF02458.15 KXX76481.1 - 5.8e-11 41.7 0.0 1e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 Transferase family p450 PF00067.22 KXX76482.1 - 5.8e-51 173.7 0.0 7.7e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXX76483.1 - 7.6e-39 133.7 0.0 2.4e-30 105.7 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.23 KXX76484.1 - 1.7e-25 89.4 4.3 3.3e-25 88.4 4.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX76484.1 - 0.027 14.6 0.2 0.07 13.2 0.2 1.7 1 0 0 1 1 1 0 Berberine and berberine like Transferase PF02458.15 KXX76485.1 - 4.7e-34 117.8 0.0 4.1e-28 98.2 0.0 2.0 2 0 0 2 2 2 2 Transferase family Condensation PF00668.20 KXX76485.1 - 0.15 10.7 0.1 0.33 9.6 0.1 1.5 1 0 0 1 1 1 0 Condensation domain p450 PF00067.22 KXX76486.1 - 1.7e-58 198.5 0.0 6.1e-58 196.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 Adap_comp_sub PF00928.21 KXX76487.1 - 8.3e-91 304.0 0.0 1.4e-90 303.2 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXX76487.1 - 7.1e-09 35.7 0.2 1.2e-08 35.0 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain adh_short PF00106.25 KXX76489.1 - 6.6e-20 71.4 0.0 9.3e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76489.1 - 6.7e-10 38.9 0.0 1.1e-09 38.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76489.1 - 2e-08 34.3 0.0 2.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX76489.1 - 0.00015 21.3 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF629 PF04780.12 KXX76489.1 - 0.074 11.6 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Hydrolase_4 PF12146.8 KXX76490.1 - 5.2e-14 52.1 0.0 1.3e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXX76490.1 - 4.2e-09 37.3 0.0 5.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KXX76490.1 - 2e-08 33.3 0.1 0.002 16.9 0.1 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KXX76490.1 - 3.2e-05 23.7 0.0 0.00098 18.8 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXX76490.1 - 7.1e-05 22.5 0.0 9.2e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXX76490.1 - 0.0027 17.2 0.0 0.61 9.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXX76490.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 KXX76491.1 - 4.4e-64 216.5 0.0 8.6e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXX76491.1 - 1.1e-56 192.3 0.0 1.8e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXX76491.1 - 5.9e-56 189.2 0.5 1.2e-55 188.2 0.5 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXX76491.1 - 4.4e-47 161.1 0.0 7.3e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX76491.1 - 7.4e-34 116.3 0.3 3.4e-33 114.1 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXX76491.1 - 3.4e-17 62.9 0.0 8.7e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXX76491.1 - 1e-15 59.0 0.0 4.9e-15 56.8 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX76491.1 - 1.6e-15 57.3 0.0 4.2e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX76491.1 - 1e-07 31.8 0.7 2.2e-07 30.7 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXX76491.1 - 1.3e-06 28.0 1.8 2e-06 27.4 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase SAT PF16073.5 KXX76491.1 - 5.1e-06 26.4 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KXX76491.1 - 6.9e-05 23.1 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXX76491.1 - 0.0013 18.1 0.4 0.0034 16.8 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain SpoVAD PF07451.11 KXX76491.1 - 0.026 13.3 0.1 0.055 12.2 0.1 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KXX76491.1 - 0.36 10.7 3.4 0.25 11.2 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Opi1 PF08618.10 KXX76492.1 - 5.8e-23 81.8 11.0 3.8e-17 62.7 0.0 3.9 3 1 1 4 4 4 3 Transcription factor Opi1 DivIVA PF05103.13 KXX76492.1 - 0.19 11.8 0.3 0.75 9.9 0.4 1.8 2 0 0 2 2 2 0 DivIVA protein Hydrolase_like PF13242.6 KXX76493.1 - 6.7e-06 26.1 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXX76493.1 - 0.00016 22.0 0.0 0.00074 19.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MBF1 PF08523.10 KXX76494.1 - 1e-23 83.6 1.4 1.9e-23 82.7 1.4 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KXX76494.1 - 1.2e-12 47.7 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KXX76494.1 - 0.00016 22.0 0.0 0.00037 20.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KXX76494.1 - 0.044 13.8 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ADH_zinc_N PF00107.26 KXX76496.1 - 1.7e-24 86.3 0.2 2.6e-24 85.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX76496.1 - 1.1e-22 81.5 0.0 1.8e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX76496.1 - 3.7e-09 36.4 0.0 6.2e-08 32.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Flocculin_t3 PF13928.6 KXX76497.1 - 0.011 16.2 1.8 0.011 16.2 1.8 3.1 3 1 0 3 3 3 0 Flocculin type 3 repeat Glyco_hydro_4 PF02056.16 KXX76497.1 - 0.1 12.2 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase CDT1_C PF16679.5 KXX76498.1 - 7.7e-26 90.4 0.6 2.4e-25 88.8 0.6 1.9 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain DLH PF01738.18 KXX76499.1 - 1.6e-20 73.6 0.1 4.7e-19 68.8 0.1 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KXX76499.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXX76499.1 - 0.14 11.8 0.0 0.96 9.0 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF1365 PF07103.11 KXX76500.1 - 3.3e-62 210.3 0.0 5.2e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) GFA PF04828.14 KXX76501.1 - 7.8e-23 80.6 0.0 1.2e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NMD3 PF04981.13 KXX76501.1 - 0.26 10.7 1.6 0.25 10.8 0.2 1.6 2 0 0 2 2 2 0 NMD3 family DZR PF12773.7 KXX76501.1 - 0.28 11.2 4.4 1.7 8.7 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 KXX76501.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.5 3 0 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.11 KXX76501.1 - 7.7 6.3 7.6 0.62 9.8 0.4 2.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain BRCT_2 PF16589.5 KXX76502.1 - 5.4e-07 29.9 0.0 9.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KXX76502.1 - 0.00012 21.9 0.1 0.00038 20.3 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain AMP-binding PF00501.28 KXX76503.1 - 4.6e-74 249.5 0.0 5.9e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXX76503.1 - 3e-19 68.7 0.5 8.1e-19 67.3 0.5 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXX76503.1 - 7.7e-14 52.4 0.4 3.6e-13 50.3 0.0 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain DUF1667 PF07892.11 KXX76503.1 - 0.046 13.8 0.0 2.3 8.4 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1667) Stn1_C PF12659.7 KXX76503.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH CDC14 PF08045.11 KXX76504.1 - 6.1e-121 402.9 0.0 6.9e-121 402.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component KilA-N PF04383.13 KXX76506.1 - 0.0003 20.6 0.0 0.0063 16.3 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Pkinase PF00069.25 KXX76507.1 - 1.5e-52 178.6 0.0 2e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76507.1 - 3e-20 72.6 0.0 5.9e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXX76507.1 - 0.054 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXX76507.1 - 0.12 12.0 0.5 0.21 11.1 0.5 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase polyprenyl_synt PF00348.17 KXX76508.1 - 3.4e-66 222.9 0.0 4.1e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pex24p PF06398.11 KXX76509.1 - 9.5e-89 297.9 0.0 1.2e-88 297.6 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 KXX76509.1 - 0.22 9.9 0.0 0.22 9.9 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3292) Ten1 PF12658.7 KXX76512.1 - 3.5e-27 94.8 0.0 4.1e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Snf7 PF03357.21 KXX76513.1 - 1.8e-31 109.1 16.1 1.8e-31 109.1 16.1 2.0 2 0 0 2 2 2 1 Snf7 Misat_Tub_SegII PF10644.9 KXX76513.1 - 0.14 12.5 1.0 0.31 11.4 1.0 1.7 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain UreD PF01774.17 KXX76514.1 - 4.2e-78 262.1 0.1 5e-78 261.9 0.1 1.1 1 0 0 1 1 1 1 UreD urease accessory protein RNA_pol_Rpc4 PF05132.14 KXX76515.1 - 7.7e-25 88.1 0.0 7.7e-25 88.1 0.0 5.1 4 2 1 5 5 5 1 RNA polymerase III RPC4 DUF2397 PF09660.10 KXX76515.1 - 2.3 7.0 7.4 3.3 6.5 6.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) Med3 PF11593.8 KXX76515.1 - 2.8 7.0 23.8 4.8 6.3 23.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NUDE_C PF04880.13 KXX76515.1 - 9.7 6.6 13.4 7.3 7.0 11.5 1.7 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region FAD_binding_3 PF01494.19 KXX76516.1 - 9.2e-14 51.4 0.1 1e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXX76516.1 - 7.2e-09 35.7 5.7 3.6e-05 23.5 0.7 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXX76516.1 - 2.2e-06 27.0 0.8 0.054 12.5 0.0 2.0 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX76516.1 - 4.2e-05 22.9 1.5 0.00077 18.8 0.6 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX76516.1 - 0.0003 19.6 0.0 0.00054 18.8 0.0 1.4 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KXX76516.1 - 0.0023 18.1 1.2 0.0042 17.3 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX76516.1 - 0.0048 16.0 2.3 0.0048 16.0 2.3 2.0 1 1 1 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KXX76516.1 - 0.0068 15.7 2.6 0.57 9.4 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXX76516.1 - 0.0099 16.4 0.1 0.19 12.3 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXX76516.1 - 0.15 10.8 0.2 0.22 10.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KXX76516.1 - 0.19 11.7 0.8 6.5 6.7 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KXX76516.1 - 0.22 10.6 0.3 0.33 10.0 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXX76516.1 - 0.25 10.5 0.1 0.35 10.1 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KXX76517.1 - 2.5e-29 102.3 40.6 2.5e-29 102.3 40.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily HA2 PF04408.23 KXX76518.1 - 4.1e-18 65.7 0.4 4.7e-17 62.2 0.0 2.7 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXX76518.1 - 6.6e-16 58.6 0.0 1.5e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXX76518.1 - 1.3e-12 47.9 0.1 4.6e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXX76518.1 - 2.3e-10 40.5 0.1 4.8e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 KXX76518.1 - 9.1e-05 22.7 0.3 0.00036 20.8 0.2 2.1 2 0 0 2 2 2 1 RWD domain AAA_22 PF13401.6 KXX76518.1 - 0.0047 17.2 1.0 0.03 14.6 1.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXX76518.1 - 0.016 15.2 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 KXX76518.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KXX76518.1 - 0.021 14.2 0.1 0.044 13.1 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KXX76518.1 - 0.093 13.2 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain dsRBD2 PF17842.1 KXX76518.1 - 0.1 12.8 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 DND1_DSRM PF14709.7 KXX76518.1 - 0.16 12.2 0.0 0.86 9.9 0.0 2.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KXX76518.1 - 0.21 12.3 2.0 18 6.1 0.0 3.3 3 0 0 3 3 2 0 Double-stranded RNA binding motif IHABP4_N PF16174.5 KXX76518.1 - 4.6 7.8 9.9 0.27 11.8 1.0 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Arm PF00514.23 KXX76519.1 - 1.8e-82 269.2 14.1 3.6e-13 49.0 0.3 7.2 7 0 0 7 7 7 7 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KXX76519.1 - 5.6e-24 83.4 3.7 8.2e-24 82.9 2.6 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KXX76519.1 - 2.8e-21 75.6 3.2 1.1e-05 25.8 0.0 6.1 4 1 2 6 6 6 5 HEAT-like repeat IBB PF01749.20 KXX76519.1 - 2.7e-18 66.2 0.5 6.4e-18 65.0 0.1 1.9 2 0 0 2 2 2 1 Importin beta binding domain HEAT PF02985.22 KXX76519.1 - 1.1e-16 59.5 2.3 2.1e-06 27.5 0.0 6.4 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 KXX76519.1 - 3.7e-16 59.3 0.1 1.7e-05 25.1 0.0 4.9 1 1 2 4 4 4 3 HEAT repeats Arm_2 PF04826.13 KXX76519.1 - 1.5e-07 31.2 0.0 0.031 13.7 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 KXX76519.1 - 0.00019 20.1 0.0 0.012 14.2 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KXX76519.1 - 0.00025 21.1 0.0 1.8 8.7 0.0 4.2 3 2 1 4 4 4 2 V-ATPase subunit H Cnd1 PF12717.7 KXX76519.1 - 0.0023 18.0 0.0 0.89 9.6 0.0 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KXX76519.1 - 0.015 15.9 0.1 0.71 10.7 0.0 3.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat NopRA1 PF16201.5 KXX76519.1 - 0.03 13.9 0.0 8.8 5.9 0.0 3.6 2 1 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 KXX76519.1 - 0.26 11.6 2.7 17 5.8 0.0 3.9 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 POT1PC PF16686.5 KXX76520.1 - 2.5e-46 157.4 0.0 7.1e-46 155.9 0.0 1.8 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KXX76520.1 - 2.7e-18 66.2 0.0 5.8e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 KXX76520.1 - 0.17 11.8 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Replication protein A OB domain STAG PF08514.11 KXX76521.1 - 4.9e-39 132.7 2.6 4.9e-39 132.7 2.6 2.2 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 KXX76521.1 - 3.4e-09 37.0 0.3 0.0003 21.1 0.0 3.3 2 1 2 4 4 4 3 HEAT repeats DUF1664 PF07889.12 KXX76521.1 - 0.0041 17.2 1.8 1.8 8.7 1.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) HEAT PF02985.22 KXX76521.1 - 0.016 15.5 0.1 7 7.2 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat TSNAXIP1_N PF15739.5 KXX76521.1 - 0.29 11.5 2.5 1 9.8 0.1 2.7 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DHR10 PF18595.1 KXX76521.1 - 5.7 7.0 13.2 1.1 9.3 6.4 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain ICE2 PF08426.10 KXX76522.1 - 5.1e-164 546.2 13.2 5.8e-164 546.0 13.2 1.0 1 0 0 1 1 1 1 ICE2 AT_hook PF02178.19 KXX76523.1 - 0.0026 17.5 39.4 0.028 14.2 0.5 4.8 4 0 0 4 4 4 4 AT hook motif CDC27 PF09507.10 KXX76523.1 - 0.1 12.0 13.6 0.12 11.7 13.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MFS_1 PF07690.16 KXX76524.1 - 1.8e-32 112.6 34.0 1.8e-32 112.6 34.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX76524.1 - 0.011 14.6 19.6 0.043 12.7 19.2 1.9 1 1 0 1 1 1 0 Sugar (and other) transporter UNC-93 PF05978.16 KXX76524.1 - 0.4 10.4 7.3 0.058 13.1 2.0 2.2 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KXX76524.1 - 3.6 6.3 16.6 1.4 7.7 2.6 3.2 2 1 2 4 4 4 0 MFS_1 like family Mito_carr PF00153.27 KXX76526.1 - 1.5e-73 242.8 0.2 1.1e-26 92.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXX76526.1 - 1.8e-14 53.9 2.1 1.7e-08 34.8 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXX76526.1 - 4e-14 51.3 0.1 1.6e-06 27.5 0.0 5.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 KXX76526.1 - 1.1e-13 49.6 2.3 3.7e-07 29.2 0.0 5.2 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KXX76526.1 - 8.9e-11 41.5 1.1 0.038 13.8 0.1 5.0 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 KXX76526.1 - 2e-10 39.7 0.5 1e-06 27.9 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KXX76526.1 - 0.035 14.4 0.0 35 4.8 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain ADH_zinc_N PF00107.26 KXX76527.1 - 7e-09 35.7 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX76527.1 - 0.037 13.9 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PQ-loop PF04193.14 KXX76528.1 - 3.6e-31 106.7 10.0 2.9e-15 55.8 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat Vma12 PF11712.8 KXX76528.1 - 0.024 14.7 1.5 0.05 13.7 1.0 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cyclin_N PF00134.23 KXX76529.1 - 1.5e-43 147.6 0.3 2.4e-43 146.9 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXX76529.1 - 3.9e-35 120.5 0.0 1e-34 119.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF2808 PF10989.8 KXX76529.1 - 0.069 13.1 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Zn_clus PF00172.18 KXX76530.1 - 0.00091 19.3 12.4 0.0018 18.4 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KXX76530.1 - 0.014 14.8 0.1 0.044 13.2 0.1 1.8 1 0 0 1 1 1 0 Histone chaperone domain CHZ Transp_cyt_pur PF02133.15 KXX76532.1 - 3.9e-38 131.4 31.4 7.1e-37 127.2 31.4 2.2 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DNA_ligase_A_M PF01068.21 KXX76533.1 - 2.5e-22 79.5 0.0 5.4e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXX76533.1 - 1.2e-20 74.6 0.1 2e-20 73.8 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KXX76533.1 - 1.8e-06 28.3 0.0 3.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA ligase MS_channel PF00924.18 KXX76536.1 - 2e-20 73.2 2.6 3.7e-20 72.3 2.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KXX76536.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KXX76536.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KXX76536.1 - 0.19 11.3 0.3 0.48 10.1 0.3 1.7 1 0 0 1 1 1 0 EF hand Peptidase_A4 PF01828.17 KXX76537.1 - 2.3e-34 118.7 2.3 4.4e-33 114.5 2.3 2.0 1 1 0 1 1 1 1 Peptidase A4 family EXS PF03124.14 KXX76538.1 - 6.2e-98 328.2 26.5 7.6e-98 327.9 26.5 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KXX76538.1 - 3.2e-84 284.1 1.3 3.2e-84 284.1 1.3 2.0 2 0 0 2 2 2 1 SPX domain CagE_TrbE_VirB PF03135.14 KXX76538.1 - 0.074 13.1 0.4 0.37 10.9 0.2 2.0 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system NDK PF00334.19 KXX76539.1 - 1.3e-53 180.6 0.0 1.5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyoxalase PF00903.25 KXX76540.1 - 3.2e-07 30.6 0.1 4.6e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KXX76540.1 - 0.025 15.4 0.0 0.035 14.9 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain GCD14 PF08704.10 KXX76541.1 - 4.5e-64 216.5 0.0 2.2e-46 158.5 0.0 2.8 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit T7SS_ESX_EspC PF10824.8 KXX76542.1 - 0.015 15.8 1.2 0.015 15.8 1.2 1.9 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm CAF1A PF12253.8 KXX76543.1 - 2e-23 82.3 2.2 2e-23 82.3 2.2 2.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A HflK_N PF12221.8 KXX76543.1 - 0.091 12.8 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Peptidase_S64 PF08192.11 KXX76543.1 - 0.81 8.1 7.5 1.8 7.0 7.5 1.5 1 0 0 1 1 1 0 Peptidase family S64 PAF-AH_p_II PF03403.13 KXX76545.1 - 2.2e-43 148.2 0.0 4.4e-36 124.2 0.0 2.2 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXX76545.1 - 0.00065 18.7 0.0 0.0027 16.7 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXX76545.1 - 0.0034 16.7 0.2 0.055 12.7 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXX76545.1 - 0.025 13.6 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_6 PF12697.7 KXX76545.1 - 4.8 7.7 16.1 0.41 11.2 7.9 2.7 1 1 0 2 2 2 0 Alpha/beta hydrolase family FLILHELTA PF10306.9 KXX76546.1 - 8.1e-30 103.1 0.0 1.8e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KXX76546.1 - 0.0092 16.5 0.5 0.015 15.8 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Peptidase_M18 PF02127.15 KXX76547.1 - 1.9e-126 422.4 0.0 2.2e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TMEM125 PF15109.6 KXX76547.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family Peptidase_M50B PF13398.6 KXX76548.1 - 4.5e-61 206.0 18.1 5.6e-61 205.7 18.1 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KXX76548.1 - 0.04 13.2 0.1 0.066 12.5 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M50 Peptidase_M41 PF01434.18 KXX76548.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 Peptidase_M36 PF02128.15 KXX76548.1 - 0.18 10.9 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Glyco_hydro_31 PF01055.26 KXX76549.1 - 9.2e-142 473.3 4.4 1.3e-141 472.8 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXX76549.1 - 2.5e-25 88.6 0.5 1e-23 83.4 0.2 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXX76549.1 - 2.9e-07 30.7 0.9 1.9e-06 28.0 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DIOX_N PF14226.6 KXX76551.1 - 2.8e-19 70.0 0.0 4.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXX76551.1 - 5.5e-13 49.3 0.0 1.1e-11 45.1 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec39 PF08314.11 KXX76552.1 - 9.8e-285 946.8 0.0 1.2e-284 946.5 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 MFAP1 PF06991.11 KXX76553.1 - 4.2e-75 252.3 31.8 4.2e-75 252.3 31.8 3.4 2 2 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Voldacs PF03517.13 KXX76555.1 - 4.2e-18 65.8 3.6 4.2e-18 65.8 3.6 2.3 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling ADH_zinc_N_2 PF13602.6 KXX76556.1 - 2e-20 74.2 0.0 5.5e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX76556.1 - 1.9e-10 40.8 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KXX76556.1 - 0.028 14.2 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DapB_N PF01113.20 KXX76556.1 - 0.074 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CRAL_TRIO PF00650.20 KXX76557.1 - 2.3e-41 141.2 0.0 3.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXX76557.1 - 3.5e-15 55.9 2.6 3.5e-15 55.9 2.6 1.6 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXX76557.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.10 KXX76558.1 - 2.2e-78 263.6 0.0 2.9e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KXX76558.1 - 5.7e-40 136.9 0.0 8.2e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PAN_1 PF00024.26 KXX76559.1 - 9.4e-06 25.5 0.1 1.6e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 KXX76559.1 - 1.2e-05 24.8 0.0 3.1e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KXX76559.1 - 0.00039 20.3 0.0 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase PAN_4 PF14295.6 KXX76559.1 - 0.12 12.3 3.7 0.24 11.3 1.5 2.2 2 0 0 2 2 2 0 PAN domain DUF4407 PF14362.6 KXX76560.1 - 0.00075 18.9 5.5 0.0012 18.3 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4763 PF15960.5 KXX76560.1 - 0.0012 18.2 5.6 0.0017 17.7 5.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) CH PF00307.31 KXX76560.1 - 0.0014 18.8 0.2 0.088 13.0 0.1 2.4 1 1 2 3 3 2 1 Calponin homology (CH) domain DUF5595 PF18077.1 KXX76560.1 - 0.0055 16.8 0.9 0.0055 16.8 0.9 3.1 3 2 1 4 4 3 1 Domain of unknown function (DUF5595) APG6_N PF17675.1 KXX76560.1 - 0.006 17.1 6.2 0.006 17.1 6.2 2.5 3 0 0 3 3 2 1 Apg6 coiled-coil region THOC7 PF05615.13 KXX76560.1 - 0.0088 16.3 6.6 0.019 15.3 6.6 1.5 1 0 0 1 1 1 1 Tho complex subunit 7 FlaC_arch PF05377.11 KXX76560.1 - 0.016 15.6 2.3 2.7 8.4 1.2 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 KXX76560.1 - 0.021 15.0 2.5 0.021 15.0 2.5 2.5 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 KXX76560.1 - 0.025 13.5 6.0 0.041 12.8 6.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) GIT_CC PF16559.5 KXX76560.1 - 0.038 13.9 1.3 0.12 12.3 1.3 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2935 PF11155.8 KXX76560.1 - 0.039 14.3 0.0 0.13 12.6 0.0 1.9 2 1 0 2 2 1 0 Domain of unknown function (DUF2935) DMPK_coil PF08826.10 KXX76560.1 - 0.04 14.0 2.9 0.04 14.0 2.9 3.2 4 0 0 4 4 3 0 DMPK coiled coil domain like NUDE_C PF04880.13 KXX76560.1 - 0.043 14.3 1.5 0.043 14.3 1.5 2.3 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Dzip-like_N PF13815.6 KXX76560.1 - 0.046 13.7 6.6 0.72 9.8 2.6 2.5 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FapA PF03961.13 KXX76560.1 - 0.052 12.2 1.4 0.069 11.8 1.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 KXX76560.1 - 0.056 13.4 10.4 0.11 12.4 4.4 3.0 3 0 0 3 3 3 0 Prefoldin subunit Fez1 PF06818.15 KXX76560.1 - 0.059 13.8 7.7 0.11 13.0 6.3 2.1 1 1 0 1 1 1 0 Fez1 DUF3958 PF13125.6 KXX76560.1 - 0.075 13.2 5.6 2.3 8.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) FlxA PF14282.6 KXX76560.1 - 0.076 13.0 2.5 3.6 7.6 2.3 2.9 3 0 0 3 3 3 0 FlxA-like protein BST2 PF16716.5 KXX76560.1 - 0.14 12.8 14.7 0.4 11.3 0.2 3.5 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Spc24 PF08286.11 KXX76560.1 - 0.15 12.3 5.8 0.068 13.4 1.1 2.5 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 KXX76560.1 - 0.17 11.9 8.6 0.059 13.5 2.2 2.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF1319 PF07028.11 KXX76560.1 - 0.22 11.8 3.0 0.69 10.1 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) DUF641 PF04859.12 KXX76560.1 - 0.24 11.7 8.3 0.31 11.4 3.8 2.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.6 KXX76560.1 - 0.28 9.8 3.6 0.081 11.6 1.1 1.5 2 0 0 2 2 2 0 AAA domain TolA_bind_tri PF16331.5 KXX76560.1 - 0.33 11.0 14.5 0.67 10.1 7.0 3.4 3 1 1 4 4 4 0 TolA binding protein trimerisation Fungal_TACC PF12709.7 KXX76560.1 - 0.35 11.3 5.0 0.74 10.3 2.6 2.6 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3450 PF11932.8 KXX76560.1 - 0.37 10.0 12.2 0.048 13.0 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF465 PF04325.13 KXX76560.1 - 0.46 10.5 11.8 4 7.6 6.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF465) DUF1640 PF07798.11 KXX76560.1 - 0.73 9.9 5.3 0.43 10.6 1.6 2.3 2 1 0 2 2 1 0 Protein of unknown function (DUF1640) KASH_CCD PF14662.6 KXX76560.1 - 0.76 9.6 11.6 3.2 7.5 11.2 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 KXX76560.1 - 0.86 9.6 13.4 0.23 11.5 5.6 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 KXX76560.1 - 0.99 9.7 5.5 2.6 8.4 1.4 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 KXX76560.1 - 1.1 9.6 16.7 3.5 8.0 0.0 4.0 3 1 1 4 4 4 0 ABC transporter C-terminal domain GrpE PF01025.19 KXX76560.1 - 1.1 8.8 12.2 0.41 10.3 5.7 2.6 2 1 1 3 3 2 0 GrpE Atg14 PF10186.9 KXX76560.1 - 1.3 8.1 7.6 1.7 7.6 4.5 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KXX76560.1 - 1.5 8.1 13.1 0.068 12.5 5.5 2.3 3 0 0 3 3 2 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 KXX76560.1 - 1.7 8.8 11.8 1.3 9.2 4.3 3.3 3 1 1 4 4 3 0 Centrosomin N-terminal motif 1 AATF-Che1 PF13339.6 KXX76560.1 - 1.9 9.2 7.0 1 10.0 2.7 2.3 1 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Nnf1 PF03980.14 KXX76560.1 - 1.9 8.9 13.6 0.24 11.8 4.1 3.3 2 1 1 3 3 3 0 Nnf1 SYCE1 PF15233.6 KXX76560.1 - 1.9 8.5 11.6 0.18 11.8 4.6 2.4 3 0 0 3 3 2 0 Synaptonemal complex central element protein 1 MCU PF04678.13 KXX76560.1 - 2.2 8.4 4.8 4.8 7.3 4.8 1.7 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Ax_dynein_light PF10211.9 KXX76560.1 - 2.3 8.1 9.6 0.91 9.4 4.3 2.4 2 1 0 3 3 2 0 Axonemal dynein light chain CENP-Q PF13094.6 KXX76560.1 - 2.7 8.2 14.7 17 5.6 11.9 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit M PF02370.16 KXX76560.1 - 3.7 8.4 9.4 3.6 8.4 3.3 3.1 2 0 0 2 2 2 0 M protein repeat SlyX PF04102.12 KXX76560.1 - 3.8 8.2 12.0 10 6.8 0.1 3.7 3 1 0 3 3 3 0 SlyX Phage_GPO PF05929.11 KXX76560.1 - 5.1 6.6 7.7 12 5.5 6.4 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ADIP PF11559.8 KXX76560.1 - 5.8 7.0 10.7 1.2 9.2 4.8 2.4 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KXX76560.1 - 5.8 7.6 7.7 5.6 7.7 4.2 2.4 2 1 1 3 3 2 0 Initiation control protein YabA HALZ PF02183.18 KXX76560.1 - 5.8 7.2 17.9 0.27 11.5 5.1 3.5 3 1 0 3 3 2 0 Homeobox associated leucine zipper Spc7 PF08317.11 KXX76560.1 - 6 5.6 11.6 19 4.0 11.3 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 KXX76560.1 - 6.2 6.7 20.8 3.5 7.5 3.5 4.3 4 1 1 5 5 4 0 Septum formation initiator IFP_35_N PF07334.13 KXX76560.1 - 6.3 6.9 7.8 14 5.9 3.5 2.9 3 0 0 3 3 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus MerR-DNA-bind PF09278.11 KXX76560.1 - 6.7 7.3 11.5 15 6.2 0.0 3.7 2 1 2 4 4 4 0 MerR, DNA binding HIP1_clath_bdg PF16515.5 KXX76560.1 - 7.8 7.2 12.8 4.5 7.9 6.8 2.8 2 2 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4201 PF13870.6 KXX76560.1 - 8.6 6.1 12.9 0.24 11.1 5.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Swi5 PF07061.11 KXX76560.1 - 8.7 6.5 8.2 3.8 7.7 2.4 3.1 3 2 0 3 3 3 0 Swi5 DUF4140 PF13600.6 KXX76560.1 - 8.8 6.8 11.1 1.2e+02 3.2 9.4 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.11 KXX76560.1 - 9.8 6.3 18.3 3.7 7.7 14.8 2.1 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KXX76560.1 - 9.9 6.2 15.4 14 5.7 12.0 2.4 2 1 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus pPIWI_RE_Y PF18156.1 KXX76561.1 - 0.12 12.7 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y DUF3669 PF12417.8 KXX76562.1 - 2.1e-16 59.9 0.0 5.3e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Zinc finger protein NACHT PF05729.12 KXX76563.1 - 1.3e-11 44.7 0.0 3.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX76563.1 - 2.8e-06 27.8 0.0 1.7e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX76563.1 - 0.00016 22.0 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXX76563.1 - 0.0015 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KXX76563.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KXX76563.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KXX76563.1 - 0.022 15.2 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ThiP_synth PF10120.9 KXX76563.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Thiamine-phosphate synthase RNA_helicase PF00910.22 KXX76563.1 - 0.029 14.8 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KXX76563.1 - 0.07 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXX76563.1 - 0.072 13.6 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXX76563.1 - 0.12 12.1 0.0 0.94 9.2 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 KXX76563.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KXX76563.1 - 0.16 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 KXX76563.1 - 0.28 10.3 0.0 0.44 9.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Rrp15p PF07890.12 KXX76565.1 - 2.3e-37 128.3 10.6 2.3e-37 128.3 10.6 1.7 2 0 0 2 2 2 1 Rrp15p PNP_UDP_1 PF01048.20 KXX76569.1 - 9.9e-14 51.2 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KXX76569.1 - 1.7e-07 31.6 0.1 6.4e-05 23.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KXX76569.1 - 7.2e-07 28.6 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KXX76569.1 - 0.0007 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX76569.1 - 0.006 17.0 0.1 0.034 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXX76569.1 - 0.0065 17.0 0.0 0.019 15.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KXX76569.1 - 0.016 14.8 0.0 0.048 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX76569.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXX76569.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_12 PF13424.6 KXX76569.1 - 0.048 14.0 0.2 9.7 6.6 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX76569.1 - 0.072 13.9 3.7 6.2 7.9 1.2 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KXX76569.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Tugs PF17840.1 KXX76569.1 - 0.08 13.1 0.9 0.31 11.2 0.9 2.0 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain FeThRed_B PF02943.15 KXX76569.1 - 0.17 11.9 1.0 0.37 10.8 1.0 1.5 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain ALMS_repeat PF18727.1 KXX76571.1 - 0.039 13.9 0.4 0.072 13.0 0.4 1.4 1 0 0 1 1 1 0 Alstrom syndrome repeat Fer2 PF00111.27 KXX76572.1 - 3e-13 49.5 0.7 5.2e-13 48.8 0.7 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 KXX76575.1 - 7.8e-15 54.6 3.5 0.00037 20.3 0.1 4.7 3 2 0 3 3 3 3 Mitochondrial carrier protein DUF908 PF06012.12 KXX76575.1 - 5.3 6.4 5.6 12 5.2 5.7 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) Glyco_hydro_61 PF03443.14 KXX76576.1 - 8.8e-70 234.8 0.1 1.2e-69 234.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXX76576.1 - 1.1e-11 44.5 6.4 3.6e-11 42.8 6.4 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3669 PF12417.8 KXX76577.1 - 1.2e-19 70.2 0.2 2.1e-19 69.5 0.2 1.4 1 0 0 1 1 1 1 Zinc finger protein Transferase PF02458.15 KXX76578.1 - 7e-23 81.0 0.0 2.9e-19 69.0 0.0 3.0 2 1 0 2 2 2 2 Transferase family HET PF06985.11 KXX76579.1 - 5.4e-37 127.4 0.6 8e-37 126.8 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 KXX76579.1 - 0.00021 21.3 0.1 0.00046 20.2 0.1 1.6 1 0 0 1 1 1 1 WW domain CD99L2 PF12301.8 KXX76580.1 - 0.025 14.9 0.3 0.025 14.9 0.3 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 MFS_1 PF07690.16 KXX76581.1 - 3.2e-24 85.5 27.4 3.2e-24 85.5 27.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily 2TM PF13239.6 KXX76581.1 - 0.023 15.0 0.9 1.9 8.9 0.7 3.5 2 2 0 2 2 2 0 2TM domain CDC45 PF02724.14 KXX76581.1 - 2.1 6.5 8.0 3.2 5.9 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 KXX76581.1 - 3.3 8.7 10.0 6.8 7.7 10.0 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ThiF PF00899.21 KXX76582.1 - 3.4e-111 370.4 0.0 2.4e-75 253.0 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KXX76582.1 - 5.5e-86 288.6 1.2 5.5e-86 288.6 1.2 2.2 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KXX76582.1 - 1.5e-32 111.6 0.1 4e-32 110.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KXX76582.1 - 3.8e-25 87.9 1.0 7.7e-25 86.9 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 KXX76582.1 - 1.2e-19 70.8 1.7 1e-18 67.8 0.6 2.4 2 0 0 2 2 2 1 Ubiquitin fold domain NAD_binding_7 PF13241.6 KXX76582.1 - 0.039 14.4 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Tap-RNA_bind PF09162.10 KXX76582.1 - 0.1 12.5 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Tap, RNA-binding FKBP_C PF00254.28 KXX76583.1 - 4.9e-27 94.1 0.0 5.8e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HET PF06985.11 KXX76584.1 - 7.5e-13 49.1 6.8 9.4e-11 42.3 0.9 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KXX76585.1 - 1.6e-05 25.5 8.5 0.0011 19.8 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX76585.1 - 0.0028 17.9 0.2 2.3 8.6 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX76585.1 - 0.11 11.4 0.2 7.3 5.4 0.1 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GCIP PF13324.6 KXX76585.1 - 0.58 9.7 1.2 0.91 9.1 1.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KXX76585.1 - 0.97 8.7 9.0 1.5 8.1 9.0 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KXX76585.1 - 1.2 9.6 13.0 2.8 8.4 13.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KXX76585.1 - 4 5.4 6.2 5.5 5.0 6.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KXX76585.1 - 6.3 5.8 12.1 11 5.0 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glycos_transf_4 PF00953.21 KXX76586.1 - 1.5e-33 116.0 9.7 1.5e-33 116.0 9.7 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 YdjC PF04794.12 KXX76587.1 - 0.025 14.6 0.0 0.071 13.1 0.0 1.7 2 0 0 2 2 2 0 YdjC-like protein ATP-synt_C PF00137.21 KXX76588.1 - 1.7e-10 41.0 12.2 1.7e-10 41.0 12.2 2.1 2 0 0 2 2 2 1 ATP synthase subunit C MOZ_SAS PF01853.18 KXX76589.1 - 5.2e-54 182.6 0.0 8.3e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXX76589.1 - 4.9e-07 29.2 1.8 0.016 14.8 0.0 2.6 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KXX76589.1 - 0.11 12.9 0.0 0.73 10.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Spt20 PF12090.8 KXX76589.1 - 6.6 6.3 11.4 12 5.4 11.4 1.4 1 0 0 1 1 1 0 Spt20 family p450 PF00067.22 KXX76590.1 - 1.4e-07 30.7 0.0 1.7e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PP-binding PF00550.25 KXX76591.1 - 0.00021 21.6 0.0 0.00047 20.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site RP1-2 PF12042.8 KXX76591.1 - 0.081 12.8 0.2 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain NDC10_II PF16787.5 KXX76592.1 - 2.5e-96 322.5 0.0 3.6e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 KXX76592.1 - 2e-15 56.8 0.5 4e-15 55.9 0.5 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.17 KXX76592.1 - 0.0019 18.4 0.5 0.015 15.6 0.0 2.5 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain F5_F8_type_C PF00754.25 KXX76592.1 - 0.034 14.3 0.7 0.077 13.1 0.7 1.5 1 0 0 1 1 1 0 F5/8 type C domain p450 PF00067.22 KXX76593.1 - 1e-45 156.4 0.0 1.4e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 KXX76596.1 - 4.2e-23 81.4 0.0 2.2e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX76596.1 - 5.4e-16 58.4 0.1 1.2e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX76596.1 - 1.3e-06 28.5 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX76596.1 - 3e-06 27.6 0.1 7.1e-05 23.1 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXX76596.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXX76596.1 - 0.036 14.6 0.0 0.063 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PhetRS_B1 PF18262.1 KXX76596.1 - 0.16 12.2 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain UQ_con PF00179.26 KXX76597.1 - 3.8e-24 84.9 0.0 7.2e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.7 KXX76597.1 - 4.8e-17 62.3 0.0 7.4e-07 29.7 0.0 3.8 2 1 2 4 4 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX76597.1 - 3.7e-16 58.8 0.4 0.023 15.2 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXX76597.1 - 8.8e-11 41.8 2.7 6.2e-05 23.2 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.12 KXX76597.1 - 1.2e-10 41.6 0.0 2.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 KXX76597.1 - 2.3e-10 40.8 0.3 0.00033 21.1 0.1 3.4 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX76597.1 - 1.5e-09 37.2 0.5 0.13 12.8 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat AAA_16 PF13191.6 KXX76597.1 - 0.00029 21.3 0.1 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX76597.1 - 0.0018 18.5 0.2 0.0063 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain SesA PF17107.5 KXX76597.1 - 0.011 15.9 0.0 0.068 13.4 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXX76597.1 - 0.029 13.7 0.7 0.2 11.0 0.0 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins KAP_NTPase PF07693.14 KXX76597.1 - 0.17 11.1 0.1 5.7 6.1 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Cyclin_N PF00134.23 KXX76597.1 - 0.23 11.2 0.7 24 4.7 0.1 3.2 3 0 0 3 3 3 0 Cyclin, N-terminal domain RCR PF12273.8 KXX76598.1 - 0.026 15.2 11.9 0.13 12.9 9.7 2.7 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Glyoxalase PF00903.25 KXX76599.1 - 4.8e-05 23.6 0.0 6.8e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PNP_UDP_1 PF01048.20 KXX76602.1 - 7.3e-15 54.9 0.1 3.2e-14 52.8 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.6 KXX76602.1 - 1.7e-08 34.6 6.0 0.0048 17.2 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KXX76602.1 - 1.4e-07 31.0 0.1 3.5e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_10 PF13374.6 KXX76602.1 - 0.00026 20.8 5.2 1.4 8.9 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX76602.1 - 0.00073 20.1 0.0 9.6 6.9 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX76602.1 - 0.002 18.8 1.3 14 6.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXX76602.1 - 0.0035 17.8 0.3 1.9 9.1 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX76602.1 - 0.0039 17.1 0.9 20 5.5 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_25 PF13481.6 KXX76602.1 - 0.0041 16.7 0.0 0.033 13.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain TPR_2 PF07719.17 KXX76602.1 - 0.011 15.8 1.8 14 6.1 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXX76602.1 - 0.021 15.4 0.8 0.25 12.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_5 PF07728.14 KXX76602.1 - 0.023 14.7 1.2 0.29 11.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXX76602.1 - 0.034 14.5 2.2 0.11 12.9 0.1 2.9 3 1 0 3 3 2 0 AAA ATPase domain AAA_22 PF13401.6 KXX76602.1 - 0.057 13.7 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXX76602.1 - 0.068 12.9 0.1 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Glyco_hydro_61 PF03443.14 KXX76603.1 - 6.8e-06 26.2 0.0 9.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 1-cysPrx_C PF10417.9 KXX76603.1 - 0.0012 18.7 0.4 0.088 12.7 0.0 2.4 2 0 0 2 2 2 2 C-terminal domain of 1-Cys peroxiredoxin Glyco_hydro_61 PF03443.14 KXX76604.1 - 6.4e-30 104.6 0.0 7.8e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 KXX76605.1 - 1.6e-36 125.6 0.0 2.1e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76605.1 - 1.1e-17 64.4 0.0 1.5e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76605.1 - 7.5e-08 32.5 0.2 5.7e-07 29.6 0.2 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXX76605.1 - 9.6e-05 22.3 0.5 0.00015 21.7 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX76605.1 - 0.0062 16.0 0.1 0.086 12.3 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXX76605.1 - 0.02 14.9 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 KXX76605.1 - 0.035 13.5 0.1 0.045 13.1 0.1 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Patatin PF01734.22 KXX76606.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Aldo_ket_red PF00248.21 KXX76608.1 - 6.4e-47 160.2 0.0 7.3e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 KXX76609.1 - 4.2e-11 43.3 0.0 0.0002 21.9 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX76609.1 - 3.2e-10 40.3 0.2 0.0059 17.2 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX76609.1 - 5.9e-10 39.1 0.2 0.00047 20.5 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KXX76609.1 - 6.1e-07 29.3 0.1 3.9e-06 26.7 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.6 KXX76609.1 - 2.2e-06 27.5 0.0 0.47 11.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXX76609.1 - 2.2e-05 24.6 0.8 0.018 15.4 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) MbeD_MobD PF04899.12 KXX76609.1 - 0.013 15.6 0.4 0.059 13.5 0.4 2.1 1 0 0 1 1 1 0 MbeD/MobD like TAF6_C PF07571.13 KXX76609.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain NB-ARC PF00931.22 KXX76611.1 - 5e-10 39.0 0.0 1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Helo_like_N PF17111.5 KXX76611.1 - 8.2e-09 35.1 2.3 1.8e-05 24.2 0.3 2.5 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins TPR_12 PF13424.6 KXX76611.1 - 3.1e-05 24.2 13.4 0.0081 16.4 0.4 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX76611.1 - 0.00035 20.5 0.8 4.1 7.8 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXX76611.1 - 0.00049 19.9 3.8 0.045 13.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXX76611.1 - 0.00068 19.9 0.0 0.0026 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX76611.1 - 0.0013 19.2 0.2 0.0013 19.2 0.2 3.0 3 1 0 3 3 2 1 AAA ATPase domain ATPase_2 PF01637.18 KXX76611.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 KXX76611.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Med11 PF10280.9 KXX76611.1 - 0.054 14.0 0.4 0.33 11.4 0.1 2.3 1 1 1 2 2 2 0 Mediator complex protein TPR_19 PF14559.6 KXX76611.1 - 0.054 14.0 6.2 7 7.2 0.1 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat Hormone_1 PF00103.20 KXX76611.1 - 0.061 13.1 0.4 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Somatotropin hormone family TPR_14 PF13428.6 KXX76611.1 - 1.7 9.7 16.2 1.5 9.8 0.4 6.2 7 1 0 7 7 5 0 Tetratricopeptide repeat Pex19 PF04614.12 KXX76611.1 - 2 8.1 4.0 11 5.8 4.0 2.2 1 1 0 1 1 1 0 Pex19 protein family LOR PF04525.12 KXX76612.1 - 2.9e-13 49.8 0.0 3.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related F-box-like PF12937.7 KXX76613.1 - 3.8e-07 29.9 0.4 1.3e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like NOA36 PF06524.12 KXX76613.1 - 2.1 7.6 5.6 4.5 6.5 5.6 1.5 1 0 0 1 1 1 0 NOA36 protein EamA PF00892.20 KXX76614.1 - 5.9e-12 45.9 32.6 4e-06 27.1 6.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 KXX76614.1 - 2.8e-10 39.7 4.6 2.8e-10 39.7 4.6 1.6 2 0 0 2 2 2 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 KXX76614.1 - 5.2 6.1 9.7 0.14 11.3 0.1 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter Sugar_tr PF00083.24 KXX76615.1 - 2.3e-76 257.5 20.8 2.6e-76 257.3 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX76615.1 - 5.3e-18 65.1 28.3 1.2e-15 57.3 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.12 KXX76615.1 - 0.056 13.4 0.3 0.056 13.4 0.3 3.7 2 1 1 4 4 4 0 Protein of unknown function (DUF1304) DUF4293 PF14126.6 KXX76615.1 - 0.075 13.3 5.2 0.087 13.1 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) MFS_1 PF07690.16 KXX76616.1 - 1.9e-34 119.1 18.0 1.9e-34 119.1 18.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXX76616.1 - 2.3e-08 33.7 1.4 2.3e-08 33.7 1.4 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Spin-Ssty PF02513.17 KXX76616.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Spin/Ssty Family FAD_binding_3 PF01494.19 KXX76617.1 - 1.2e-22 80.7 2.1 6.8e-11 42.0 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXX76617.1 - 0.00013 22.1 0.9 0.00044 20.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX76617.1 - 0.00032 20.0 0.0 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX76617.1 - 0.00049 20.6 2.2 0.0014 19.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX76617.1 - 0.00053 19.7 1.4 0.00053 19.7 1.4 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXX76617.1 - 0.03 13.6 0.6 1.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXX76617.1 - 0.057 13.4 0.0 0.22 11.5 0.0 2.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 KXX76617.1 - 0.093 11.8 0.0 1.3 8.0 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Epimerase PF01370.21 KXX76618.1 - 1.4e-17 64.0 0.0 1.8e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX76618.1 - 1.9e-12 46.8 0.0 2.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXX76618.1 - 6.3e-09 35.7 0.0 8.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXX76618.1 - 1e-08 34.7 0.0 3.8e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXX76618.1 - 2.9e-07 30.5 0.0 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KXX76618.1 - 3.7e-06 27.0 0.0 6.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXX76618.1 - 4.6e-06 26.0 0.0 1e-05 24.9 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXX76618.1 - 8.2e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KXX76618.1 - 0.00022 21.5 0.0 0.00035 20.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KXX76618.1 - 0.00093 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 KXX76618.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KXX76618.1 - 0.038 13.5 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KXX76618.1 - 0.045 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TIR_2 PF13676.6 KXX76618.1 - 0.05 14.2 0.2 1.4 9.6 0.0 2.3 2 0 0 2 2 2 0 TIR domain Semialdhyde_dh PF01118.24 KXX76618.1 - 0.098 13.1 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SNARE PF05739.19 KXX76619.1 - 8.3 6.5 6.5 14 5.8 6.5 1.3 1 0 0 1 1 1 0 SNARE domain Mito_fiss_reg PF05308.11 KXX76620.1 - 0.46 10.5 6.7 0.55 10.3 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXX76620.1 - 2.2 7.7 8.3 3 7.2 8.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC_tran PF00005.27 KXX76621.1 - 1.2e-51 174.8 0.0 4.1e-30 105.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXX76621.1 - 2.6e-48 165.0 18.4 3.7e-29 102.2 5.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXX76621.1 - 1.1e-08 34.8 2.5 0.0054 16.2 0.5 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXX76621.1 - 2.4e-08 34.7 0.3 0.00024 21.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXX76621.1 - 6.4e-07 29.9 0.1 0.0043 17.5 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KXX76621.1 - 5e-06 26.5 0.3 0.35 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KXX76621.1 - 1.9e-05 23.8 0.1 0.019 14.1 0.2 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KXX76621.1 - 5.2e-05 22.9 0.3 0.2 11.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX76621.1 - 0.00027 21.2 0.3 4.1 7.7 0.1 3.5 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 KXX76621.1 - 0.00034 20.8 0.4 0.036 14.2 0.1 2.9 3 0 0 3 3 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KXX76621.1 - 0.00035 20.5 0.2 0.66 9.9 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase IstB_IS21 PF01695.17 KXX76621.1 - 0.00038 20.2 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KXX76621.1 - 0.0012 18.9 0.4 0.14 12.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KXX76621.1 - 0.0031 17.0 0.7 7.5 6.0 0.1 3.2 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXX76621.1 - 0.0058 16.4 0.4 1.3 8.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 KXX76621.1 - 0.0088 15.3 0.5 4.6 6.4 0.1 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KXX76621.1 - 0.011 15.7 0.1 6.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 KXX76621.1 - 0.021 15.2 0.1 11 6.5 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXX76621.1 - 0.022 14.3 0.0 2.1 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXX76621.1 - 0.027 13.7 0.0 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 KXX76621.1 - 0.028 14.1 0.7 1.6 8.3 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KXX76621.1 - 0.032 13.1 2.4 2.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 KXX76621.1 - 0.077 12.8 0.1 7.4 6.3 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase cobW PF02492.19 KXX76621.1 - 0.096 12.3 1.3 0.64 9.6 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KXX76621.1 - 0.097 12.4 0.9 6.3 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXX76621.1 - 0.11 12.9 0.2 29 5.1 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Dynamin_N PF00350.23 KXX76621.1 - 0.11 12.6 0.3 14 5.7 0.0 2.9 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KXX76621.1 - 0.13 12.9 0.2 12 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KXX76621.1 - 0.13 12.3 0.2 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SecY PF00344.20 KXX76622.1 - 3.5e-71 240.0 9.1 4.4e-71 239.6 9.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KXX76622.1 - 1e-17 63.6 0.3 3.2e-17 62.1 0.3 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p RhoGAP PF00620.27 KXX76623.1 - 1.3e-10 41.3 0.0 1.1e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 RhoGAP domain AAA_33 PF13671.6 KXX76624.1 - 6e-13 49.2 0.2 8.3e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KXX76624.1 - 5.6e-08 33.1 0.2 1e-07 32.2 0.2 1.4 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KXX76624.1 - 2.6e-07 31.2 0.1 6.4e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXX76624.1 - 0.00019 21.7 0.7 0.00076 19.8 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXX76624.1 - 0.00031 21.2 0.1 0.00079 19.9 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KXX76624.1 - 0.00073 20.0 0.1 0.0027 18.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX76624.1 - 0.0014 19.1 0.2 0.0027 18.1 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KXX76624.1 - 0.0017 18.9 0.0 0.0027 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KXX76624.1 - 0.002 17.9 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase Rad17 PF03215.15 KXX76624.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain dNK PF01712.19 KXX76624.1 - 0.0056 16.6 0.0 0.03 14.2 0.0 1.8 1 1 0 2 2 2 1 Deoxynucleoside kinase APS_kinase PF01583.20 KXX76624.1 - 0.0059 16.5 0.1 0.014 15.3 0.1 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin2 PF13189.6 KXX76624.1 - 0.0071 16.5 0.2 0.017 15.2 0.2 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_14 PF13173.6 KXX76624.1 - 0.0082 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXX76624.1 - 0.011 15.6 0.0 0.05 13.5 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CoaE PF01121.20 KXX76624.1 - 0.02 14.5 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase ABC_tran PF00005.27 KXX76624.1 - 0.021 15.3 0.0 0.027 15.0 0.0 1.3 1 1 0 1 1 1 0 ABC transporter IPT PF01745.16 KXX76624.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_22 PF13401.6 KXX76624.1 - 0.047 14.0 0.0 0.079 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXX76624.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KXX76624.1 - 0.086 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KXX76624.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 KXX76624.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parathyroid PF01279.17 KXX76624.1 - 0.12 13.0 0.2 0.22 12.2 0.2 1.5 1 0 0 1 1 1 0 Parathyroid hormone family tRNA_lig_kinase PF08303.11 KXX76624.1 - 0.12 12.4 0.0 0.6 10.2 0.0 1.9 1 1 0 2 2 2 0 tRNA ligase kinase domain Aminotran_5 PF00266.19 KXX76625.1 - 1.1e-18 67.4 0.0 8e-18 64.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_M54 PF07998.11 KXX76626.1 - 1.3e-11 44.8 0.0 2.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M54 DUF1639 PF07797.14 KXX76626.1 - 0.15 12.1 0.2 0.97 9.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) Fungal_trans PF04082.18 KXX76627.1 - 4.3e-21 75.1 0.1 1.4e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX76627.1 - 4.2e-09 36.4 9.2 7e-09 35.7 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.20 KXX76628.1 - 2.8e-108 362.9 0.1 2.5e-107 359.7 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXX76628.1 - 8e-24 84.4 0.0 1.5e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain IPPT PF01715.17 KXX76629.1 - 2e-61 207.7 0.5 3.1e-61 207.1 0.5 1.2 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.8 KXX76629.1 - 2.3e-07 30.9 0.4 4.1e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.16 KXX76629.1 - 8.4e-06 25.3 0.1 2e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.7 KXX76629.1 - 0.00063 20.0 0.5 0.0011 19.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_33 PF13671.6 KXX76629.1 - 0.0013 18.9 0.2 0.018 15.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KXX76629.1 - 0.0036 17.8 0.2 0.11 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX76629.1 - 0.0041 17.5 1.1 0.035 14.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KXX76629.1 - 0.037 14.4 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KXX76629.1 - 0.042 13.6 0.2 0.53 10.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase IstB_IS21 PF01695.17 KXX76629.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 KXX76629.1 - 0.049 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXX76629.1 - 0.055 13.7 0.3 0.91 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXX76629.1 - 0.071 13.4 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ring_hydroxyl_A PF00848.19 KXX76629.1 - 0.078 12.9 0.1 1.8 8.5 0.0 2.2 1 1 1 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) CbiA PF01656.23 KXX76629.1 - 0.084 12.9 0.0 0.19 11.8 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Adeno_IVa2 PF02456.15 KXX76629.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein zf-U1 PF06220.12 KXX76629.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.6 KXX76629.1 - 0.13 13.1 0.2 0.29 12.1 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 KXX76629.1 - 0.15 12.2 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.7 KXX76629.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PhoH PF02562.16 KXX76629.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Hpr_kinase_C PF07475.12 KXX76629.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Glyco_hydro_26 PF02156.15 KXX76630.1 - 2.1e-86 290.2 4.0 2.6e-86 289.9 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 KXX76630.1 - 3.1e-28 98.5 0.6 5.2e-28 97.7 0.6 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) Endotoxin_C PF03944.14 KXX76630.1 - 0.17 12.2 0.2 0.33 11.3 0.2 1.4 1 0 0 1 1 1 0 delta endotoxin Cadherin-like PF12733.7 KXX76630.1 - 0.23 12.0 3.0 0.17 12.4 0.3 2.1 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain GMC_oxred_N PF00732.19 KXX76631.1 - 4.4e-59 200.3 0.0 2.5e-58 197.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX76631.1 - 2.1e-34 119.1 0.0 3.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX76631.1 - 1.9e-05 23.9 3.3 0.0051 15.9 2.4 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXX76631.1 - 2.1e-05 23.8 1.1 3.3e-05 23.1 1.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXX76631.1 - 0.00011 21.9 1.8 0.00047 19.9 1.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX76631.1 - 0.0002 20.7 0.1 0.00057 19.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXX76631.1 - 0.0023 18.1 1.2 0.006 16.8 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX76631.1 - 0.023 14.0 3.2 0.36 10.1 3.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX76631.1 - 0.037 13.3 0.9 0.073 12.3 0.6 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX76631.1 - 0.18 11.8 0.5 0.37 10.8 0.5 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KXX76631.1 - 0.47 9.1 1.2 0.78 8.4 1.2 1.3 1 0 0 1 1 1 0 HI0933-like protein F-box-like PF12937.7 KXX76632.1 - 0.003 17.4 0.1 0.008 16.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX76632.1 - 0.0063 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain FAD_binding_4 PF01565.23 KXX76634.1 - 2.6e-21 75.8 1.7 3.7e-21 75.3 0.8 1.7 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KXX76634.1 - 2.1e-12 46.9 0.0 4.5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Transp_cyt_pur PF02133.15 KXX76635.1 - 2.5e-09 36.5 42.3 3.1e-09 36.1 35.5 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1294 PF06961.13 KXX76635.1 - 0.36 11.1 4.4 1.5 9.1 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) His_Phos_2 PF00328.22 KXX76636.1 - 9.2e-09 35.1 0.2 4.2e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF5325 PF17259.2 KXX76636.1 - 0.2 11.6 0.3 0.41 10.6 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5325) DUF2463 PF09591.10 KXX76637.1 - 0.028 14.3 0.3 0.028 14.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) BTB PF00651.31 KXX76638.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Hap4_Hap_bind PF10297.9 KXX76640.1 - 1.5e-08 34.4 6.9 1.5e-08 34.4 6.9 2.9 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KXX76640.1 - 0.00028 20.9 14.6 0.0023 18.0 10.7 2.4 1 1 1 2 2 2 2 bZIP transcription factor SPATA24 PF15175.6 KXX76640.1 - 0.011 15.6 1.6 0.018 14.9 1.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4482 PF14818.6 KXX76640.1 - 0.024 15.5 3.3 0.072 14.0 3.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) bZIP_Maf PF03131.17 KXX76640.1 - 0.1 13.1 8.3 0.18 12.3 8.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2397 PF09660.10 KXX76640.1 - 0.14 11.1 4.5 0.22 10.4 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) CLZ PF16526.5 KXX76640.1 - 0.15 12.4 3.7 0.37 11.2 3.7 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 KXX76640.1 - 0.61 10.1 4.6 1.2 9.2 4.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit TEX13 PF15186.6 KXX76640.1 - 0.63 9.7 7.4 1 9.0 7.4 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Fmp27_WPPW PF10359.9 KXX76640.1 - 0.69 8.7 3.8 1 8.2 3.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Jnk-SapK_ap_N PF09744.9 KXX76640.1 - 0.75 10.0 11.9 1.2 9.4 11.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PspB PF06667.12 KXX76640.1 - 1.8 8.7 3.3 4.5 7.4 2.6 2.0 2 1 0 2 2 2 0 Phage shock protein B bZIP_2 PF07716.15 KXX76640.1 - 4 7.6 16.1 24 5.1 0.6 2.3 1 1 1 2 2 2 0 Basic region leucine zipper COG2 PF06148.11 KXX76641.1 - 8.7e-25 87.4 0.2 1.8e-24 86.3 0.1 1.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KXX76641.1 - 1.2e-05 25.5 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KXX76641.1 - 6.5e-05 22.9 0.0 0.0002 21.4 0.0 1.9 2 1 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 KXX76641.1 - 0.036 12.7 0.1 0.057 12.1 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family HR1 PF02185.16 KXX76641.1 - 0.066 13.3 0.3 0.91 9.7 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat Spc7 PF08317.11 KXX76641.1 - 0.074 11.9 0.3 0.14 11.0 0.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KXX76641.1 - 0.18 12.3 0.3 1.7 9.1 0.0 2.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Ribosomal_L1 PF00687.21 KXX76642.1 - 3.9e-22 79.0 0.0 4.6e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 KXX76643.1 - 1.7e-104 349.1 0.1 2.2e-104 348.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXX76643.1 - 8.8e-41 139.7 0.1 2.2e-40 138.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KXX76643.1 - 0.00099 18.5 0.2 0.0022 17.4 0.2 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Choline_transpo PF04515.12 KXX76644.1 - 2.6e-81 273.3 20.2 2.6e-81 273.3 20.2 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter SUV3_C PF12513.8 KXX76644.1 - 1.1 9.2 3.7 0.55 10.2 0.2 2.2 3 0 0 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal IspA PF04279.15 KXX76644.1 - 1.3 9.1 18.8 0.28 11.3 13.2 2.5 2 1 0 2 2 2 0 Intracellular septation protein A Dynamin_N PF00350.23 KXX76645.1 - 8e-11 42.3 0.0 3.2e-10 40.3 0.0 2.0 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KXX76645.1 - 4.8e-06 26.6 0.6 0.00061 19.7 0.0 3.4 4 1 0 4 4 4 1 RsgA GTPase MMR_HSR1 PF01926.23 KXX76645.1 - 1e-05 25.6 0.0 0.0021 18.1 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXX76645.1 - 1.1e-05 26.0 0.0 0.00063 20.3 0.0 2.9 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KXX76645.1 - 9.6e-05 22.8 0.0 9.6e-05 22.8 0.0 3.4 5 0 0 5 5 5 1 AAA ATPase domain Roc PF08477.13 KXX76645.1 - 0.0073 16.5 0.0 0.029 14.6 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXX76645.1 - 0.018 15.3 1.7 0.57 10.4 0.0 3.6 4 0 0 4 4 3 0 AAA domain AIG1 PF04548.16 KXX76645.1 - 0.032 13.6 0.5 0.39 10.0 0.0 2.5 2 1 1 3 3 3 0 AIG1 family Sec8_exocyst PF04048.14 KXX76645.1 - 0.038 13.9 2.0 8.4 6.3 0.0 3.6 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain SMC_hinge PF06470.13 KXX76645.1 - 0.046 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain NB-ARC PF00931.22 KXX76645.1 - 0.083 12.1 0.1 2.8 7.0 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain FeoB_N PF02421.18 KXX76645.1 - 0.098 12.2 0.0 9.1 5.8 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF919 PF06034.11 KXX76645.1 - 0.11 12.4 0.6 0.36 10.7 0.6 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) AAA_18 PF13238.6 KXX76645.1 - 0.12 13.0 0.2 0.48 11.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.14 KXX76645.1 - 0.12 11.6 0.0 1.4 8.1 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain tRNA_synthFbeta PF17759.1 KXX76646.1 - 2.1e-45 154.8 0.0 3.1e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KXX76646.1 - 5.8e-28 96.9 0.2 1.6e-26 92.3 0.1 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KXX76646.1 - 4.3e-25 88.4 0.0 7.2e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KXX76646.1 - 8.6e-16 58.0 0.0 4.4e-13 49.3 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain Ank_2 PF12796.7 KXX76648.1 - 8.9e-50 167.2 0.0 6.4e-12 45.9 0.0 5.4 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX76648.1 - 1.7e-35 120.9 3.7 1.5e-10 41.3 0.0 7.5 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KXX76648.1 - 1.2e-32 110.9 1.7 2.3e-06 27.8 0.1 8.5 8 1 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 KXX76648.1 - 4.3e-31 103.5 0.6 7.2e-06 26.0 0.0 9.7 10 0 0 10 10 9 6 Ankyrin repeat Ank_5 PF13857.6 KXX76648.1 - 1.2e-28 98.8 1.1 2e-08 34.3 0.1 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXX76648.1 - 1.6e-05 25.4 0.1 7e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXX76648.1 - 0.00042 20.3 0.0 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KXX76648.1 - 0.0079 15.5 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily PEGA PF08308.11 KXX76648.1 - 0.018 14.9 0.0 8.2 6.4 0.0 3.8 4 0 0 4 4 4 0 PEGA domain RICH PF05062.12 KXX76648.1 - 0.027 14.8 0.6 0.06 13.7 0.6 1.6 1 0 0 1 1 1 0 RICH domain RNA_helicase PF00910.22 KXX76648.1 - 0.073 13.5 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.6 KXX76648.1 - 0.09 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXX76649.1 - 0.00021 21.3 0.0 0.0006 19.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 KXX76649.1 - 0.0043 17.7 0.1 0.012 16.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_19 PF13245.6 KXX76649.1 - 0.049 14.0 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXX76649.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX76649.1 - 0.1 12.9 0.0 0.58 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 KXX76650.1 - 0.0027 15.3 19.7 0.0027 15.3 19.7 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF3584) HET PF06985.11 KXX76651.1 - 2e-16 60.7 0.0 3.2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TERF2_RBM PF16772.5 KXX76651.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif DUF4360 PF14273.6 KXX76652.1 - 2.6e-45 154.5 0.2 3e-45 154.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.16 KXX76653.1 - 2.1e-34 119.0 52.4 2.1e-34 119.0 52.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX76653.1 - 8.4e-12 44.3 23.2 2.4e-11 42.8 23.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RTX PF02382.15 KXX76653.1 - 0.98 9.0 6.9 1.8 8.2 6.9 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein Romo1 PF10247.9 KXX76655.1 - 3.8e-30 104.0 15.1 4.9e-30 103.7 15.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KXX76655.1 - 0.017 15.5 4.1 0.022 15.2 4.1 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family LapA_dom PF06305.11 KXX76655.1 - 0.47 10.3 1.9 7 6.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Cu-oxidase_3 PF07732.15 KXX76656.1 - 1.4e-42 144.4 5.6 8.4e-40 135.5 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXX76656.1 - 3.4e-33 115.0 0.2 8e-31 107.3 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXX76656.1 - 2e-28 98.8 9.7 3.1e-28 98.2 3.7 3.4 3 1 0 3 3 3 1 Multicopper oxidase UDP-g_GGTase PF06427.11 KXX76656.1 - 0.039 14.1 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase FHA PF00498.26 KXX76658.1 - 3.9e-17 62.4 0.1 8.7e-17 61.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXX76658.1 - 6.3e-05 23.2 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GAS PF13851.6 KXX76658.1 - 0.0075 15.6 3.0 0.0075 15.6 3.0 3.0 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding DUF3037 PF11236.8 KXX76658.1 - 0.69 10.4 2.5 0.78 10.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) XhlA PF10779.9 KXX76658.1 - 1.2 9.3 8.5 3.1 8.1 3.7 2.5 2 0 0 2 2 2 0 Haemolysin XhlA DUF4407 PF14362.6 KXX76658.1 - 3.7 6.8 7.3 7.6 5.8 6.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC106 PF15794.5 KXX76658.1 - 6.6 6.4 16.1 0.58 9.8 7.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Podoplanin PF05808.11 KXX76659.1 - 0.00019 21.6 2.5 0.00051 20.2 2.5 1.7 1 0 0 1 1 1 1 Podoplanin SDA1 PF05285.12 KXX76659.1 - 0.0059 16.1 1.7 0.0087 15.5 1.7 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 KXX76659.1 - 0.012 15.0 4.8 0.017 14.5 4.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KXX76659.1 - 6.1 4.9 6.8 9.1 4.3 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_60s PF00428.19 KXX76660.1 - 3 8.5 17.9 2.2 9.0 9.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein MFS_1 PF07690.16 KXX76661.1 - 1.6e-37 129.2 53.6 1.9e-36 125.8 52.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 KXX76662.1 - 3.3e-23 82.5 0.5 4.4e-23 82.0 0.5 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX76662.1 - 2.3e-19 70.0 1.4 3.9e-19 69.3 1.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KXX76662.1 - 1.9e-05 24.7 0.1 3.3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KXX76662.1 - 0.0046 16.4 0.3 0.018 14.5 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXX76662.1 - 0.032 13.4 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein SIR2 PF02146.17 KXX76663.1 - 2.5e-54 183.9 0.0 3.8e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family GST_N_3 PF13417.6 KXX76663.1 - 2.6e-20 72.6 0.0 5.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX76663.1 - 6.5e-19 68.0 0.0 2.4e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXX76663.1 - 1.5e-10 41.3 0.0 2.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX76663.1 - 2.4e-07 30.7 1.9 6.5e-07 29.3 0.2 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX76663.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Latarcin PF10279.9 KXX76663.1 - 1.2 9.6 3.3 21 5.6 0.0 2.4 2 0 0 2 2 2 0 Latarcin precursor PCI PF01399.27 KXX76664.1 - 3.6e-19 69.2 1.1 1.2e-18 67.5 0.0 2.5 3 1 0 3 3 3 1 PCI domain Pkinase_Tyr PF07714.17 KXX76664.1 - 0.045 13.0 0.1 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase TPR_1 PF00515.28 KXX76664.1 - 0.4 10.6 2.9 3.5 7.6 0.7 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXX76664.1 - 2.8 8.3 6.8 1.1 9.6 0.5 3.6 3 2 0 3 3 3 0 Tetratricopeptide repeat CWC25 PF12542.8 KXX76665.1 - 7e-26 91.1 2.5 7e-26 91.1 2.5 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.9 KXX76665.1 - 8.8e-08 32.2 3.8 8.8e-08 32.2 3.8 3.1 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Thioredoxin PF00085.20 KXX76666.1 - 5e-28 97.1 0.0 6.9e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXX76666.1 - 7.2e-07 29.6 0.1 2.7e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXX76666.1 - 4.4e-06 26.9 0.0 0.00057 20.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KXX76666.1 - 5.9e-05 22.6 0.0 8.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXX76666.1 - 0.00065 19.6 0.1 0.36 10.8 0.0 2.2 1 1 1 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 KXX76666.1 - 0.00099 18.8 0.1 0.57 9.9 0.0 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.6 KXX76666.1 - 0.004 17.3 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like SelK_SelG PF10961.8 KXX76666.1 - 0.0064 17.1 0.0 0.0064 17.1 0.0 2.2 1 1 1 2 2 2 1 Selenoprotein SelK_SelG Thioredoxin_9 PF14595.6 KXX76666.1 - 0.0088 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KXX76666.1 - 0.1 12.4 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 KXX76666.1 - 0.21 11.6 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Rsm22 PF09243.10 KXX76667.1 - 7e-30 104.2 0.0 9.2e-29 100.6 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 KXX76667.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX76667.1 - 0.065 14.0 0.0 0.2 12.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KXX76668.1 - 3.2e-16 59.2 0.2 5.6e-16 58.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX76668.1 - 1.4e-07 31.6 8.5 3.3e-07 30.3 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXX76668.1 - 2.9e-07 30.6 10.7 0.0035 17.7 1.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX76668.1 - 0.0008 20.1 14.3 0.0071 17.1 0.8 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXX76668.1 - 0.0022 18.3 0.1 0.0064 16.8 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KXX76668.1 - 0.0075 16.1 1.1 0.0075 16.1 1.1 3.1 3 0 0 3 3 3 2 zinc-finger of a C2HC-type DUF5318 PF17249.2 KXX76668.1 - 0.25 11.1 1.2 0.44 10.3 0.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5318) zf-C2H2_11 PF16622.5 KXX76668.1 - 3 7.7 10.2 1.3 8.9 0.7 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KXX76668.1 - 6.9 7.3 14.2 0.55 10.8 2.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain 4HBT PF03061.22 KXX76669.1 - 3.2e-05 24.2 0.0 7.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily TP_methylase PF00590.20 KXX76670.1 - 1.9e-46 158.7 0.1 3.7e-46 157.7 0.1 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 KXX76670.1 - 1.2e-05 24.8 0.0 3.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal TRH PF05438.12 KXX76670.1 - 0.091 12.5 0.3 0.14 11.9 0.3 1.2 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Biotin_lipoyl PF00364.22 KXX76671.1 - 1.6e-15 56.7 0.4 2.9e-15 55.8 0.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXX76671.1 - 1.6e-06 27.8 1.9 0.018 14.9 0.0 3.3 3 1 1 4 4 4 2 Biotin-lipoyl like HlyD_3 PF13437.6 KXX76671.1 - 0.0021 18.8 0.0 1.6 9.5 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 KXX76671.1 - 0.006 15.8 0.0 1.8 7.7 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Sirohm_synth_M PF14824.6 KXX76672.1 - 1.3e-10 40.5 0.1 2.9e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 KXX76672.1 - 2.1e-10 40.9 0.0 3.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding DUF3678 PF12435.8 KXX76672.1 - 0.041 13.3 4.3 0.9 9.0 2.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Ras PF00071.22 KXX76673.1 - 5e-54 182.3 0.0 5.7e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX76673.1 - 1.2e-21 77.2 0.0 2.3e-21 76.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX76673.1 - 2.9e-09 36.6 0.0 4.9e-09 35.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXX76673.1 - 0.0028 17.0 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KXX76673.1 - 0.0043 16.2 0.0 0.0069 15.6 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KXX76673.1 - 0.0058 16.1 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXX76673.1 - 0.024 14.7 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXX76673.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter BPL_LplA_LipB PF03099.19 KXX76674.1 - 0.0079 16.1 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.9 KXX76675.1 - 1.7e-70 237.3 0.0 2.1e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PLRV_ORF5 PF01690.17 KXX76675.1 - 0.62 8.7 6.1 0.94 8.1 6.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Methyltrn_RNA_3 PF02598.17 KXX76676.1 - 8.4e-102 340.5 0.0 9.5e-102 340.3 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 KXX76676.1 - 0.0021 18.2 0.0 0.028 14.6 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family Mpv17_PMP22 PF04117.12 KXX76677.1 - 9.8e-15 54.5 1.4 9.8e-15 54.5 1.4 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Kelch_4 PF13418.6 KXX76678.1 - 8.3e-38 128.2 5.7 5.2e-07 29.6 0.6 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KXX76678.1 - 2.9e-33 113.0 4.4 1.8e-12 47.1 0.4 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KXX76678.1 - 1.1e-31 108.2 3.0 6.8e-12 44.8 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KXX76678.1 - 9.9e-31 105.2 4.9 8.1e-08 32.1 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KXX76678.1 - 4.8e-29 100.1 9.0 2.7e-06 27.5 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KXX76678.1 - 7.3e-20 70.1 8.5 3.6e-07 29.9 0.4 6.7 6 1 0 6 6 6 5 Kelch motif Filament PF00038.21 KXX76678.1 - 1.7e-05 24.6 31.2 1.7e-05 24.6 31.2 4.1 2 2 1 3 3 3 1 Intermediate filament protein Ribosomal_S27e PF01667.17 KXX76679.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KXX76679.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 KXX76679.1 - 0.67 10.0 7.1 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type RNR_inhib PF08591.10 KXX76680.1 - 1.1e-30 107.0 0.1 3.7e-30 105.4 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Raptor_N PF14538.6 KXX76681.1 - 2.2e-62 209.4 0.0 4e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KXX76681.1 - 1.7e-06 28.6 6.5 4.9 8.2 0.0 6.6 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX76681.1 - 5.4e-05 23.4 0.0 20 5.6 0.0 4.9 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KXX76681.1 - 0.00088 19.3 0.5 0.29 11.2 0.0 2.8 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 KXX76681.1 - 0.011 15.9 0.2 48 4.6 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Atx10homo_assoc PF09759.9 KXX76681.1 - 0.031 14.3 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 KXX76681.1 - 0.035 14.5 0.8 3 8.3 0.0 3.5 3 1 0 3 3 3 0 HEAT repeats Cnd1 PF12717.7 KXX76681.1 - 0.1 12.6 0.0 0.63 10.1 0.0 2.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Phosducin PF02114.16 KXX76682.1 - 2.3e-13 49.7 0.0 3.5e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KXX76682.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin NPH-II PF12011.8 KXX76682.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA helicase NPH-II HNH_2 PF13391.6 KXX76683.1 - 6.1e-13 48.7 0.1 2.1e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease MoaF PF10703.9 KXX76684.1 - 0.029 14.3 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 MoaF N-terminal domain SIP1 PF04938.12 KXX76685.1 - 8.2e-10 38.8 0.0 2.2e-07 30.8 0.0 3.0 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) tRNA-synt_2 PF00152.20 KXX76686.1 - 5.2e-74 249.2 0.0 6.4e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXX76686.1 - 3.1e-05 23.9 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF5539 PF17693.1 KXX76686.1 - 0.057 13.1 3.3 0.11 12.2 2.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5539) NARP1 PF12569.8 KXX76686.1 - 1.1 8.1 7.5 1.7 7.5 7.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Borrelia_P83 PF05262.11 KXX76686.1 - 3.6 6.0 7.0 5.2 5.4 7.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein EMC1_C PF07774.13 KXX76687.1 - 1.4e-77 260.2 0.0 3e-77 259.1 0.0 1.6 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KXX76687.1 - 1.5e-22 80.4 8.1 2.4e-20 73.1 4.7 2.7 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KXX76687.1 - 7e-05 22.6 2.6 0.049 13.6 0.0 5.1 6 0 0 6 6 6 1 PQQ enzyme repeat LRR_8 PF13855.6 KXX76688.1 - 1.8e-06 27.6 0.5 3.8e-06 26.6 0.5 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXX76688.1 - 0.00022 21.5 0.2 0.00056 20.2 0.2 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) adh_short PF00106.25 KXX76689.1 - 2.1e-32 112.2 0.0 5.6e-32 110.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76689.1 - 3.1e-23 82.5 0.0 5.3e-13 49.1 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76689.1 - 4.8e-09 36.4 0.0 4.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 KR domain Med17 PF10156.9 KXX76691.1 - 7.4e-73 245.8 0.0 9.6e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.20 KXX76692.1 - 8.4e-188 622.5 0.3 1e-105 353.1 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KXX76692.1 - 0.15 11.7 0.1 0.74 9.4 0.1 2.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain YIF1 PF03878.15 KXX76693.1 - 1.4e-96 322.7 0.7 1.6e-96 322.5 0.7 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KXX76693.1 - 0.00012 21.8 5.1 0.00012 21.8 5.1 1.5 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 KXX76694.1 - 1.8e-84 284.1 0.0 2.5e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KXX76694.1 - 9.7e-52 175.5 0.2 1.7e-51 174.7 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KXX76694.1 - 9.4e-09 35.4 0.1 3e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KXX76694.1 - 1.9e-06 27.0 0.1 4.3e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KXX76694.1 - 0.0003 20.6 0.2 0.00059 19.6 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXX76694.1 - 0.0017 18.8 0.4 0.0045 17.4 0.1 1.9 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 KXX76694.1 - 0.0048 17.0 0.4 1.3 9.0 0.0 2.9 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KXX76694.1 - 0.014 15.8 0.1 0.36 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KXX76694.1 - 0.022 14.9 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXX76694.1 - 0.041 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase SMC_N PF02463.19 KXX76694.1 - 0.055 12.9 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KXX76694.1 - 0.06 12.6 0.0 0.23 10.7 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 KXX76694.1 - 0.069 13.2 0.7 0.48 10.5 0.7 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXX76694.1 - 0.086 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KXX76694.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.27 KXX76695.1 - 1.8e-49 168.8 0.0 3.2e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KXX76695.1 - 4.7e-46 157.6 1.4 1.3e-45 156.2 0.8 2.0 2 0 0 2 2 2 1 FAT domain UME PF08064.13 KXX76695.1 - 2.4e-32 110.9 0.3 2e-31 107.9 0.2 2.8 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KXX76695.1 - 2.6e-16 59.1 0.0 7.7e-16 57.6 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 KXX76695.1 - 0.014 15.8 2.3 0.2 12.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FANCI_HD1 PF14679.6 KXX76695.1 - 0.024 14.6 0.5 14 5.7 0.0 4.4 4 0 0 4 4 4 0 FANCI helical domain 1 TPR_16 PF13432.6 KXX76695.1 - 0.047 14.3 1.2 3.2 8.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXX76695.1 - 0.062 13.8 1.0 0.18 12.3 0.1 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation FBD PF08387.10 KXX76695.1 - 0.089 12.7 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 FBD HEAT_2 PF13646.6 KXX76695.1 - 0.11 12.9 2.5 1.7 9.1 0.1 3.9 3 1 0 3 3 3 0 HEAT repeats TPR_14 PF13428.6 KXX76695.1 - 0.2 12.6 7.1 11 7.2 0.2 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-PARP PF00645.18 KXX76696.1 - 2.1e-22 79.8 0.7 2.1e-22 79.8 0.7 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Trypan_PARP PF05887.11 KXX76696.1 - 1 9.3 90.3 0.45 10.5 26.3 3.7 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 KXX76698.1 - 6.1e-68 229.0 0.0 8.4e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76698.1 - 3.4e-31 108.5 0.0 5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXX76698.1 - 6.1e-14 52.5 0.6 2.7e-13 50.4 0.6 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXX76698.1 - 4.7e-09 36.0 0.0 1.4e-08 34.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 KXX76698.1 - 7.6e-08 32.6 0.0 3.6e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 KXX76698.1 - 0.0014 17.7 0.3 0.0038 16.2 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXX76698.1 - 0.016 14.6 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E3_15_3 PF03307.14 KXX76698.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region APH PF01636.23 KXX76698.1 - 0.043 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXX76698.1 - 0.069 12.8 0.8 5.6 6.5 0.1 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KXX76698.1 - 0.07 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fe_hyd_lg_C PF02906.14 KXX76699.1 - 2.2e-50 171.6 0.0 5.3e-50 170.4 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.7 KXX76700.1 - 0.00029 21.5 10.1 0.00029 21.5 10.1 4.3 3 1 1 4 4 4 1 SUZ domain DUF812 PF05667.11 KXX76700.1 - 0.011 14.7 1.4 0.014 14.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) API5 PF05918.11 KXX76700.1 - 0.4 9.4 5.2 0.54 9.0 5.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) eIF3_subunit PF08597.10 KXX76700.1 - 3.3 7.5 16.2 3 7.7 4.6 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit zf-H2C2_2 PF13465.6 KXX76701.1 - 4.5e-07 30.0 9.7 3.3e-06 27.3 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 KXX76701.1 - 2e-05 25.1 4.7 0.15 12.7 0.0 2.8 2 1 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KXX76701.1 - 2.1e-05 24.4 0.5 0.061 13.3 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX76701.1 - 2.5e-05 24.5 0.3 2.5e-05 24.5 0.3 3.5 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX76701.1 - 0.0002 21.9 2.9 0.012 16.4 0.3 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXX76701.1 - 0.062 13.1 0.4 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KXX76701.1 - 0.29 11.5 1.1 6.4 7.2 0.2 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sina PF03145.16 KXX76701.1 - 0.3 11.0 6.8 1.3 8.9 1.9 2.1 1 1 1 2 2 2 0 Seven in absentia protein family zf-H2C2_5 PF13909.6 KXX76701.1 - 0.46 10.3 1.9 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain NUDE_C PF04880.13 KXX76701.1 - 1.5 9.3 4.2 0.71 10.3 0.1 2.3 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region LRR_6 PF13516.6 KXX76704.1 - 4.1e-11 42.0 9.7 0.041 13.9 0.0 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KXX76704.1 - 2.3e-05 24.6 15.2 0.082 13.4 0.0 5.2 5 0 0 5 5 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXX76704.1 - 0.00096 19.4 1.8 14 6.7 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KXX76704.1 - 0.0025 17.5 15.1 1.2 9.0 0.1 5.3 4 1 0 4 4 4 2 Leucine rich repeat DUF2052 PF09747.9 KXX76704.1 - 1.1 9.3 18.0 1.6 8.8 18.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpc4 PF05132.14 KXX76704.1 - 1.3 9.4 5.6 2.2 8.7 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 KXX76704.1 - 1.5 7.8 18.9 2 7.3 18.9 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 KXX76704.1 - 1.6 8.5 14.6 2.6 7.8 14.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KXX76704.1 - 3.1 6.0 17.1 4.9 5.3 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 KXX76704.1 - 6.8 6.7 16.3 12 5.9 16.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 NOA36 PF06524.12 KXX76704.1 - 7.2 5.8 11.7 11 5.3 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein DARPP-32 PF05395.12 KXX76704.1 - 7.8 6.7 20.2 20 5.3 20.2 1.6 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 ATP11 PF06644.11 KXX76704.1 - 8.5 6.1 10.8 13 5.4 10.8 1.2 1 0 0 1 1 1 0 ATP11 protein Dus PF01207.17 KXX76705.1 - 5.9e-08 32.2 0.0 0.00019 20.6 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) O_Spanin_T7 PF17531.2 KXX76707.1 - 0.23 11.5 1.2 0.89 9.7 1.2 2.0 1 0 0 1 1 1 0 outer-membrane spanin sub-unit Glyco_hydro_18 PF00704.28 KXX76708.1 - 5e-83 279.4 1.7 6e-83 279.1 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3153 PF11353.8 KXX76708.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Proteasome PF00227.26 KXX76709.1 - 3e-46 157.3 0.1 3.8e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KXX76709.1 - 2.7e-13 49.1 0.5 2.7e-13 49.1 0.5 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DUF2722 PF10846.8 KXX76711.1 - 0.0022 17.0 17.5 0.0031 16.5 17.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Cmc1 PF08583.10 KXX76711.1 - 0.008 16.2 0.6 0.045 13.8 0.6 2.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_S64 PF08192.11 KXX76711.1 - 0.12 10.8 5.6 0.17 10.3 5.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Suf PF05843.14 KXX76711.1 - 0.51 10.3 14.3 1.1 9.2 14.3 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 KXX76711.1 - 0.95 7.7 19.0 0.24 9.6 15.4 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Rxt3 PF08642.10 KXX76711.1 - 1.8 9.4 5.1 0.38 11.5 1.2 1.9 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Spt20 PF12090.8 KXX76711.1 - 2.3 7.8 34.9 4 7.0 34.9 1.3 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 KXX76711.1 - 2.7 6.6 7.5 3.5 6.2 7.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCDC53 PF10152.9 KXX76711.1 - 2.8 8.3 17.7 0.47 10.8 12.7 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SKA1 PF07160.12 KXX76711.1 - 2.9 7.7 15.4 0.067 13.0 8.6 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Pex14_N PF04695.13 KXX76711.1 - 3.1 8.4 23.6 0.55 10.9 19.8 1.7 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.7 KXX76711.1 - 3.5 5.6 8.6 5.1 5.1 8.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_DNAp_acc PF04929.12 KXX76711.1 - 5 6.0 8.8 7.1 5.5 8.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CLN3 PF02487.17 KXX76711.1 - 6.4 5.7 4.6 12 4.8 4.6 1.4 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 KXX76711.1 - 8 5.1 12.6 1.3 7.7 8.7 1.6 2 0 0 2 2 2 0 Presenilin DUF2076 PF09849.9 KXX76711.1 - 8.5 6.3 27.1 0.023 14.8 17.0 1.8 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2076) NUP214 PF16755.5 KXX76712.1 - 5e-06 26.0 0.0 9.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KXX76712.1 - 0.0027 17.9 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG PF13634.6 KXX76712.1 - 0.0081 17.0 2.9 0.0081 17.0 2.9 5.4 3 1 1 4 4 4 2 Nucleoporin FG repeat region ER_lumen_recept PF00810.18 KXX76713.1 - 6.2e-44 150.4 9.5 9.8e-44 149.7 9.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF1516 PF07457.11 KXX76713.1 - 0.009 16.2 0.4 0.022 15.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) Pex2_Pex12 PF04757.14 KXX76713.1 - 0.03 13.9 1.7 0.051 13.2 1.7 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF2227 PF09988.9 KXX76713.1 - 0.064 13.1 4.1 0.16 11.8 4.0 1.7 1 1 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) PQ-loop PF04193.14 KXX76713.1 - 0.13 12.1 0.0 0.13 12.1 0.0 3.1 4 0 0 4 4 4 0 PQ loop repeat ATP_sub_h PF10775.9 KXX76714.1 - 2.9e-26 91.2 0.6 4.4e-26 90.7 0.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h CDH-cyt PF16010.5 KXX76715.1 - 2e-19 70.0 2.2 3.8e-19 69.1 2.2 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KXX76715.1 - 1.9e-07 31.3 0.3 6.5e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.9 KXX76715.1 - 0.0017 18.1 5.5 0.0017 18.1 5.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) YtpI PF14007.6 KXX76715.1 - 0.13 12.4 2.8 0.44 10.7 0.6 2.4 2 0 0 2 2 2 0 YtpI-like protein AIRC PF00731.20 KXX76717.1 - 3.3e-60 201.9 0.1 6.5e-60 201.0 0.1 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KXX76717.1 - 2.4e-47 160.7 0.0 4.9e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KXX76717.1 - 2.5e-13 49.5 0.0 4.9e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KXX76717.1 - 3.7e-05 23.4 0.0 8.8e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KXX76717.1 - 0.0084 15.6 0.0 0.043 13.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 KXX76717.1 - 0.015 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXX76717.1 - 0.02 15.4 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain PrpR_N PF06506.11 KXX76717.1 - 0.037 13.6 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Propionate catabolism activator LTV PF04180.14 KXX76717.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Low temperature viability protein Fer2_3 PF13085.6 KXX76718.1 - 1.5e-33 115.1 0.0 2.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KXX76718.1 - 1.4e-08 35.1 6.0 1.4e-08 35.1 6.0 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXX76718.1 - 3e-07 30.4 3.4 3e-07 30.4 3.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXX76718.1 - 3.3e-07 30.7 8.3 3.3e-07 30.7 8.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KXX76718.1 - 0.0041 17.0 0.2 0.0041 17.0 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 KXX76718.1 - 0.017 15.3 0.4 0.55 10.4 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXX76718.1 - 0.017 15.7 5.7 0.017 15.7 5.7 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 KXX76718.1 - 0.12 12.2 0.4 0.2 11.5 0.4 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DNA_pol3_tau_4 PF12168.8 KXX76718.1 - 0.26 11.9 1.6 0.61 10.7 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_9 PF13187.6 KXX76718.1 - 0.39 10.9 10.8 2.6 8.3 9.1 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain WD40 PF00400.32 KXX76720.1 - 8.3e-39 130.9 21.2 6e-09 36.4 1.5 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 KXX76720.1 - 9.3e-16 57.1 3.3 1.7e-15 56.2 3.3 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KXX76720.1 - 1.2e-15 57.5 1.8 0.088 13.1 0.0 6.5 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX76720.1 - 0.00046 19.2 0.0 14 4.5 0.0 4.2 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXX76720.1 - 0.0048 16.8 0.0 3.4 7.5 0.0 3.5 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KXX76720.1 - 0.0052 16.2 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KXX76720.1 - 0.017 14.4 0.0 5.3 6.3 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 KXX76720.1 - 0.075 11.5 0.4 5.6 5.4 0.0 3.2 3 1 0 3 3 3 0 Cytochrome D1 heme domain Lactonase PF10282.9 KXX76720.1 - 0.17 11.1 0.0 13 4.9 0.0 2.7 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Pkinase PF00069.25 KXX76721.1 - 2.3e-66 223.9 0.0 2.9e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76721.1 - 4.4e-29 101.5 0.0 6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXX76721.1 - 0.0083 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXX76721.1 - 0.021 13.6 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_C PF00433.24 KXX76721.1 - 0.028 15.1 0.2 0.028 15.1 0.2 2.1 2 0 0 2 2 2 0 Protein kinase C terminal domain Kinase-like PF14531.6 KXX76721.1 - 0.046 13.0 0.0 0.089 12.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KXX76721.1 - 0.082 12.8 0.1 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXX76721.1 - 0.18 11.4 0.0 4.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cyclin_N PF00134.23 KXX76722.1 - 1.4e-10 41.0 0.1 2.3e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KXX76722.1 - 0.17 11.9 0.2 0.35 11.0 0.2 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat NAM-associated PF14303.6 KXX76723.1 - 2 9.1 8.9 3.4 8.4 8.9 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CDC45 PF02724.14 KXX76723.1 - 2.1 6.5 7.3 2.7 6.2 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3269 PF11673.8 KXX76724.1 - 0.06 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) Pkinase PF00069.25 KXX76725.1 - 2.5e-26 92.6 0.0 3.8e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76725.1 - 8.1e-10 38.4 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX76725.1 - 0.046 12.5 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2009 PF09418.10 KXX76726.1 - 0.26 10.3 0.0 0.34 9.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Mito_fiss_reg PF05308.11 KXX76732.1 - 0.49 10.4 4.0 0.76 9.8 4.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Methyltransf_23 PF13489.6 KXX76733.1 - 6.4e-19 68.4 0.0 1.5e-18 67.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX76733.1 - 3.2e-13 49.7 0.0 2.9e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX76733.1 - 1.7e-12 47.8 0.0 5.1e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX76733.1 - 5.1e-11 43.2 0.0 3.9e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX76733.1 - 1.9e-09 38.0 0.0 4.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXX76733.1 - 2e-05 24.1 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXX76733.1 - 0.00086 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXX76733.1 - 0.001 18.6 0.0 0.0027 17.2 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXX76733.1 - 0.0017 17.9 0.0 0.005 16.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXX76733.1 - 0.0051 16.2 0.0 2.4 7.4 0.0 2.6 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXX76733.1 - 0.008 15.5 0.0 0.019 14.3 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KXX76733.1 - 0.049 13.4 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase MFS_1 PF07690.16 KXX76735.1 - 4.8e-21 75.1 29.6 4.8e-21 75.1 29.6 2.7 1 1 1 3 3 3 3 Major Facilitator Superfamily DHR10 PF18595.1 KXX76736.1 - 0.14 12.3 21.5 0.16 12.1 10.4 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain CDC27 PF09507.10 KXX76736.1 - 8.3 5.7 12.4 5.5 6.3 4.1 2.6 3 0 0 3 3 3 0 DNA polymerase subunit Cdc27 CALM_bind PF16025.5 KXX76737.1 - 0.046 14.2 2.3 0.082 13.4 2.3 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding BORCS7 PF16088.5 KXX76737.1 - 0.11 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 SLC35F PF06027.12 KXX76738.1 - 1e-90 304.3 21.2 1.5e-90 303.7 21.2 1.3 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KXX76738.1 - 1.1e-08 35.3 31.5 6.5e-06 26.4 15.9 3.1 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KXX76738.1 - 1.5e-08 34.0 3.3 1.5e-08 34.0 3.3 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like FUSC-like PF12805.7 KXX76738.1 - 0.13 11.3 5.1 0.059 12.4 0.5 2.4 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS PAP_assoc PF03828.19 KXX76739.1 - 1.6e-16 60.2 0.1 3.5e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXX76739.1 - 2e-06 28.0 0.0 3.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_1 PF00561.20 KXX76743.1 - 2.5e-47 161.7 0.0 7.4e-47 160.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXX76743.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase RAC_head PF16717.5 KXX76745.1 - 1.2e-31 109.5 2.4 1.2e-31 109.5 2.4 3.6 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KXX76745.1 - 4e-19 68.5 2.1 2.7e-18 65.8 2.1 2.6 1 0 0 1 1 1 1 DnaJ domain TraH PF06122.11 KXX76745.1 - 0.38 10.0 4.7 0.65 9.2 4.7 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein RRM_1 PF00076.22 KXX76746.1 - 4.6e-10 39.2 0.0 7.5e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXX76746.1 - 0.00017 21.5 0.1 0.0003 20.7 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXX76746.1 - 0.039 13.8 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KXX76746.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif NUDIX PF00293.28 KXX76747.1 - 4e-05 23.7 0.1 5.9e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain TauD PF02668.16 KXX76748.1 - 7.9e-30 104.5 0.4 1e-29 104.2 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NUDIX PF00293.28 KXX76749.1 - 9.3e-18 64.5 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_M43 PF05572.13 KXX76750.1 - 2.6e-16 59.9 0.4 4.6e-16 59.1 0.2 1.6 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXX76750.1 - 0.02 15.1 1.3 0.038 14.1 1.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 KXX76750.1 - 0.046 12.9 0.8 0.07 12.3 0.8 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M7 PF02031.16 KXX76750.1 - 0.053 13.6 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.24 KXX76750.1 - 0.057 13.3 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KXX76750.1 - 0.1 13.1 0.1 0.22 12.0 0.1 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like ABM PF03992.16 KXX76750.1 - 0.12 12.5 0.2 1.4 9.0 0.1 2.4 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Reprolysin_4 PF13583.6 KXX76750.1 - 0.24 11.0 0.8 0.49 10.0 0.3 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Tyrosinase PF00264.20 KXX76751.1 - 2.9e-53 181.4 0.0 3.6e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Complex1_LYR PF05347.15 KXX76752.1 - 0.00013 21.9 0.1 0.00026 21.0 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXX76752.1 - 0.0005 20.8 0.1 0.00079 20.1 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.11 KXX76752.1 - 0.079 13.1 0.1 0.089 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Sterol_MT_C PF08498.10 KXX76753.1 - 8.7e-28 96.4 0.8 1.5e-27 95.6 0.8 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KXX76753.1 - 4e-22 78.7 0.0 8.3e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX76753.1 - 1.4e-20 73.8 0.0 4.6e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX76753.1 - 7.7e-18 64.7 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXX76753.1 - 1.9e-12 47.1 0.1 2.7e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KXX76753.1 - 1.3e-11 45.1 0.0 5.6e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX76753.1 - 4e-11 43.0 0.0 6.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX76753.1 - 6.1e-11 42.1 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KXX76753.1 - 8.1e-05 21.4 0.0 0.00013 20.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KXX76753.1 - 0.00025 20.8 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KXX76753.1 - 0.00027 20.6 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KXX76753.1 - 0.00052 19.5 0.0 0.0013 18.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXX76753.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXX76753.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 KXX76753.1 - 0.0046 16.0 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 KXX76753.1 - 0.0073 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 KXX76753.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Transket_pyr PF02779.24 KXX76754.1 - 1.4e-46 158.4 0.0 1.9e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXX76754.1 - 1.8e-36 124.7 0.1 5e-36 123.3 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain AIG2_2 PF13772.6 KXX76755.1 - 1.6e-05 25.2 0.0 6.4e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KXX76755.1 - 0.00067 20.3 0.0 0.00098 19.7 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like YqcI_YcgG PF08892.11 KXX76755.1 - 0.053 13.4 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 YqcI/YcgG family PMM PF03332.13 KXX76756.1 - 2.1e-11 44.0 0.0 3e-11 43.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KXX76756.1 - 3.2e-07 30.4 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXX76756.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase MS_channel PF00924.18 KXX76756.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel iPGM_N PF06415.13 KXX76757.1 - 6.3e-79 264.4 0.0 8.6e-79 264.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KXX76757.1 - 1e-67 228.2 0.0 1.1e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KXX76757.1 - 6.6e-06 25.7 0.0 0.00015 21.3 0.0 2.2 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.24 KXX76757.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Phage_int_SAM_1 PF02899.17 KXX76758.1 - 0.00014 22.1 1.0 0.0022 18.3 0.0 2.3 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain Sirohm_synth_C PF14823.6 KXX76758.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal GCR1_C PF12550.8 KXX76759.1 - 2.2e-19 69.5 0.9 3.9e-19 68.7 0.9 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 KXX76759.1 - 6.4e-16 58.3 0.1 1.5e-15 57.1 0.0 1.6 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 F5_F8_type_C PF00754.25 KXX76759.1 - 0.0013 18.9 0.7 0.0029 17.7 0.7 1.5 1 0 0 1 1 1 1 F5/8 type C domain RhlB PF12300.8 KXX76759.1 - 0.67 10.1 4.2 0.15 12.2 0.5 1.8 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB ADK PF00406.22 KXX76760.1 - 1.3e-26 93.5 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXX76760.1 - 5.6e-17 62.4 0.0 7.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXX76760.1 - 4.5e-08 33.4 0.0 1.4e-07 31.8 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXX76760.1 - 7.6e-06 26.5 0.0 3.8e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KXX76760.1 - 0.0011 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase Ploopntkinase3 PF18751.1 KXX76760.1 - 0.0044 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA PF00004.29 KXX76760.1 - 0.016 15.7 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX76760.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX76760.1 - 0.052 13.9 0.0 0.097 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXX76760.1 - 0.061 13.6 0.0 0.086 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXX76760.1 - 0.094 13.2 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KXX76760.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXX76760.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXX76760.1 - 0.21 10.8 0.0 1.3 8.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin CYTH PF01928.21 KXX76761.1 - 2.5e-11 43.8 0.0 4.5e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 CYTH domain NAD_binding_1 PF00175.21 KXX76762.1 - 9.4e-28 97.0 0.0 1.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXX76762.1 - 4e-16 59.2 0.0 5.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXX76762.1 - 5.2e-09 36.4 0.0 2.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Gpi1 PF05024.15 KXX76763.1 - 2.7e-79 265.6 7.5 6.8e-79 264.3 7.5 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.12 KXX76763.1 - 1.7e-24 85.9 3.9 3.2e-24 84.9 3.9 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) 7tm_1 PF00001.21 KXX76763.1 - 0.00032 20.1 0.8 0.001 18.4 0.4 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) COX17 PF05051.13 KXX76763.1 - 0.021 15.2 0.3 0.046 14.1 0.3 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) TBCC PF07986.12 KXX76764.1 - 8.5e-32 109.4 0.0 1.3e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXX76764.1 - 5.2e-09 36.6 0.1 9.9e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Radical_SAM PF04055.21 KXX76765.1 - 1.5e-13 51.5 0.1 3.3e-13 50.3 0.1 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXX76765.1 - 3.3e-06 27.4 0.0 5.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXX76765.1 - 1.7e-05 24.9 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain DNA_pol_A_exo1 PF01612.20 KXX76766.1 - 1.1e-42 145.7 0.2 1.9e-42 144.9 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KXX76766.1 - 3.4e-27 95.0 0.2 9.4e-27 93.5 0.2 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KXX76766.1 - 9.1e-10 38.4 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 HRDC domain PAT1 PF09770.9 KXX76766.1 - 0.11 10.8 20.7 0.16 10.2 20.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.13 KXX76766.1 - 0.55 9.2 19.2 0.81 8.7 19.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Prefoldin PF02996.17 KXX76767.1 - 5.2e-36 123.2 0.0 7.9e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit THOC7 PF05615.13 KXX76767.1 - 0.014 15.6 1.4 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 Prefoldin_2 PF01920.20 KXX76767.1 - 0.032 14.2 5.1 0.19 11.7 0.0 2.8 3 0 0 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 KXX76767.1 - 0.033 14.2 0.1 5.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BCAS3 PF12490.8 KXX76767.1 - 0.086 12.3 0.7 0.12 11.8 0.7 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 End3 PF12761.7 KXX76767.1 - 0.095 12.9 2.3 0.3 11.2 0.1 2.4 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 SlyX PF04102.12 KXX76767.1 - 0.39 11.4 6.4 0.64 10.7 0.1 3.3 3 1 0 3 3 3 0 SlyX Med9 PF07544.13 KXX76768.1 - 9.6e-15 54.4 0.1 9.7e-14 51.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Asp PF00026.23 KXX76769.1 - 5.5e-110 367.7 0.5 6.5e-110 367.4 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX76769.1 - 8.1e-17 62.0 1.3 3e-15 56.9 0.7 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXX76769.1 - 2.9e-05 24.6 0.1 0.68 10.6 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KXX76769.1 - 0.0014 19.2 0.0 2.1 8.9 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KXX76769.1 - 0.041 13.7 0.0 0.38 10.5 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal TauD PF02668.16 KXX76770.1 - 5.9e-40 137.7 4.0 3.5e-25 89.3 0.2 2.4 3 0 0 3 3 3 2 Taurine catabolism dioxygenase TauD, TfdA family UvrC_HhH_N PF08459.11 KXX76770.1 - 0.023 14.6 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal ANAPC4_WD40 PF12894.7 KXX76772.1 - 0.0011 19.2 0.0 0.017 15.4 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TLP-20 PF06088.11 KXX76772.1 - 3.8 7.4 6.6 8.4 6.3 6.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HlyIII PF03006.20 KXX76775.1 - 4.4e-49 167.2 17.1 1.2e-44 152.7 11.4 2.1 1 1 1 2 2 2 2 Haemolysin-III related Pkinase PF00069.25 KXX76776.1 - 1.5e-54 185.1 0.0 2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76776.1 - 1.1e-32 113.3 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX76776.1 - 0.00022 20.7 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXX76776.1 - 0.00082 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXX76776.1 - 0.014 14.2 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXX76776.1 - 0.037 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KXX76776.1 - 0.047 13.3 0.0 0.2 11.3 0.0 1.8 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXX76776.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXX76776.1 - 0.16 10.9 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TNT PF14021.6 KXX76777.1 - 2.4e-34 117.7 0.1 5.2e-34 116.7 0.1 1.5 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin DEAD PF00270.29 KXX76778.1 - 5.4e-43 146.8 0.1 8.4e-43 146.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX76778.1 - 1.4e-16 60.8 0.0 6.5e-16 58.7 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXX76778.1 - 4.2e-14 52.5 0.0 8.7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXX76778.1 - 8.6e-05 22.6 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MEF2_binding PF09047.10 KXX76778.1 - 0.071 13.0 0.5 0.18 11.7 0.5 1.7 1 0 0 1 1 1 0 MEF2 binding CBM_1 PF00734.18 KXX76779.1 - 2.4e-10 40.2 17.5 2.4e-10 40.2 17.5 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Esterase_phd PF10503.9 KXX76779.1 - 0.018 14.6 0.4 0.038 13.5 0.4 1.6 1 0 0 1 1 1 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXX76779.1 - 0.025 14.0 0.9 0.042 13.3 0.9 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXX76779.1 - 0.039 13.8 0.1 0.039 13.8 0.1 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXX76779.1 - 0.14 12.8 0.3 0.19 12.3 0.3 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_10 PF00331.20 KXX76780.1 - 7.3e-106 353.9 0.2 8.5e-106 353.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KXX76780.1 - 4.4e-14 52.1 11.6 4.4e-14 52.1 11.6 2.0 3 0 0 3 3 3 1 Fungal cellulose binding domain LysM PF01476.20 KXX76783.1 - 1.3e-09 37.9 0.0 0.0033 17.4 0.0 3.2 3 0 0 3 3 3 3 LysM domain Glycoprotein PF03409.15 KXX76783.1 - 0.21 10.4 5.0 1 8.1 0.3 2.0 2 0 0 2 2 2 0 Transmembrane glycoprotein Glyco_hydro_62 PF03664.13 KXX76785.1 - 3e-148 492.5 7.8 3.5e-148 492.2 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Peptidase_M43 PF05572.13 KXX76786.1 - 1.5e-10 41.2 2.1 1.8e-10 41.0 1.4 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXX76786.1 - 0.0031 17.7 1.5 0.022 14.9 0.8 2.0 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXX76786.1 - 0.0054 17.3 0.7 0.0088 16.6 0.7 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXX76786.1 - 0.0079 15.9 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXX76786.1 - 0.0095 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 KXX76786.1 - 0.043 13.7 0.7 0.059 13.3 0.7 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Sterile PF03015.19 KXX76786.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.25 KXX76788.1 - 3.7e-07 29.8 0.0 9.5e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76788.1 - 0.00072 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76788.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 KR domain OTT_1508_deam PF14441.6 KXX76789.1 - 3.1e-11 43.1 0.0 8.7e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DALR_2 PF09190.11 KXX76789.1 - 0.0096 16.4 0.0 3.2 8.3 0.0 2.4 2 0 0 2 2 2 2 DALR domain DUF3844 PF12955.7 KXX76790.1 - 3.6e-37 126.7 2.8 3.6e-37 126.7 2.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 KXX76790.1 - 0.095 13.1 8.3 0.2 12.1 8.3 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.15 KXX76790.1 - 0.13 12.5 6.9 0.3 11.3 6.9 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain 3HCDH_RFF PF18321.1 KXX76790.1 - 0.2 12.2 3.1 8.7 6.9 0.4 2.7 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain WW PF00397.26 KXX76792.1 - 5e-08 32.9 6.2 1.5e-07 31.4 6.2 1.9 1 0 0 1 1 1 1 WW domain KinB_sensor PF16767.5 KXX76792.1 - 0.0038 17.7 2.0 0.0061 17.0 2.0 1.2 1 0 0 1 1 1 1 Sensor domain of alginate biosynthesis sensor protein KinB DUF4404 PF14357.6 KXX76792.1 - 2.9 8.6 5.7 4.8 7.9 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Rhodanese PF00581.20 KXX76793.1 - 0.0035 17.8 0.0 0.0053 17.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain LSM PF01423.22 KXX76794.1 - 3e-22 78.1 0.4 3.3e-22 77.9 0.4 1.0 1 0 0 1 1 1 1 LSM domain DUF948 PF06103.11 KXX76795.1 - 0.078 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF896 PF05979.12 KXX76795.1 - 0.45 10.4 0.0 0.45 10.4 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) SlyX PF04102.12 KXX76795.1 - 4.1 8.1 5.5 1.1 9.9 1.4 2.2 2 0 0 2 2 2 0 SlyX Zip PF02535.22 KXX76796.1 - 7.4e-54 183.2 1.1 1.7e-53 182.0 1.1 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter TM2 PF05154.16 KXX76796.1 - 0.14 12.5 3.1 1.9 8.9 0.6 2.8 2 0 0 2 2 2 0 TM2 domain AXE1 PF05448.12 KXX76797.1 - 0.0068 15.1 0.0 0.015 14.0 0.0 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) RGS PF00615.19 KXX76798.1 - 0.00021 21.6 0.0 0.0013 19.0 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2721 PF11026.8 KXX76798.1 - 0.16 11.9 0.4 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4381 PF14316.6 KXX76798.1 - 0.36 11.0 0.0 0.36 11.0 0.0 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4381) Peptidase_C14 PF00656.22 KXX76799.1 - 2.6e-60 204.4 0.0 3.3e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DAO_C PF16901.5 KXX76799.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Raptor_N PF14538.6 KXX76799.1 - 0.2 11.6 0.3 4 7.4 0.0 2.8 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain ZapB PF06005.12 KXX76800.1 - 0.13 12.7 0.7 0.47 10.9 0.7 1.9 1 0 0 1 1 1 0 Cell division protein ZapB Malic_M PF03949.15 KXX76801.1 - 3.3e-88 295.3 0.1 4.4e-88 294.9 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXX76801.1 - 4.9e-66 222.0 0.0 7.4e-66 221.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain CDH-cyt PF16010.5 KXX76802.1 - 5.1e-48 163.2 3.6 6.5e-48 162.8 3.6 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KXX76802.1 - 0.00017 21.8 0.0 0.0008 19.6 0.0 1.9 1 1 1 2 2 2 1 DOMON domain BNR_4 PF15892.5 KXX76804.1 - 1.3e-79 267.4 2.2 1.8e-79 266.9 2.2 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member BNR PF02012.20 KXX76804.1 - 2.1 8.7 4.3 0.72 10.1 0.3 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat Zn_clus PF00172.18 KXX76805.1 - 8.3e-05 22.6 3.5 0.00016 21.7 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 KXX76806.1 - 1.1e-25 90.6 0.4 3e-25 89.2 0.4 1.6 1 1 0 1 1 1 1 Beta-lactamase Glyco_tranf_2_3 PF13641.6 KXX76807.1 - 1.5e-25 90.5 0.1 1.9e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXX76807.1 - 2.9e-07 30.1 0.4 1.3e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXX76807.1 - 5.8e-07 29.5 0.0 8.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Enkurin PF13864.6 KXX76807.1 - 0.049 14.1 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 Calmodulin-binding OPT PF03169.15 KXX76808.1 - 1.7e-80 271.4 51.9 2e-80 271.2 51.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_tr PF00083.24 KXX76809.1 - 7.9e-116 387.6 21.0 9.1e-116 387.4 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX76809.1 - 7e-24 84.4 46.9 1.8e-22 79.7 12.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 KXX76810.1 - 5.5e-09 36.5 8.9 6.8e-05 23.3 2.5 3.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Ribosomal_L14 PF00238.19 KXX76811.1 - 7.5e-33 113.2 0.0 9e-33 113.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF5427 PF10310.9 KXX76812.1 - 3.4e-181 603.3 0.0 3.9e-181 603.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KXX76812.1 - 0.012 15.8 1.3 0.022 15.0 0.2 2.0 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain F-box PF00646.33 KXX76813.1 - 1.3e-09 37.7 1.0 1.8e-05 24.5 0.0 3.7 4 0 0 4 4 4 2 F-box domain F-box-like PF12937.7 KXX76813.1 - 1.5e-05 24.8 0.5 0.0008 19.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXX76813.1 - 0.016 15.1 0.0 0.046 13.6 0.0 1.8 1 0 0 1 1 1 0 F-box LRR_4 PF12799.7 KXX76813.1 - 0.17 12.3 0.0 40 4.8 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Sigma70_ner PF04546.13 KXX76813.1 - 0.18 11.7 5.0 0.46 10.3 5.0 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 KXX76813.1 - 8.4 5.6 10.0 14 4.9 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein Fungal_trans PF04082.18 KXX76815.1 - 1e-08 34.5 0.0 2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.25 KXX76816.1 - 0.00021 21.5 0.0 0.00029 21.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PFL-like PF02901.15 KXX76817.1 - 0.17 10.5 0.0 0.23 10.1 0.0 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase-like Fungal_trans_2 PF11951.8 KXX76818.1 - 1.4e-05 24.2 1.2 1.7e-05 23.8 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 KXX76819.1 - 1.2e-52 179.5 0.0 2.9e-52 178.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX76819.1 - 3.9e-05 23.6 0.0 8.6e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX76819.1 - 0.0041 16.6 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family E1-E2_ATPase PF00122.20 KXX76820.1 - 8.4e-39 133.0 12.1 8.6e-31 106.9 0.1 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXX76820.1 - 6.6e-25 87.9 6.2 6.6e-25 87.9 6.2 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KXX76820.1 - 4.6e-19 68.3 0.0 9e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX76820.1 - 2e-18 67.5 0.1 6.5e-15 56.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX76820.1 - 1.4e-15 56.8 2.2 1.6e-15 56.5 0.2 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXX76820.1 - 0.0011 18.8 0.2 0.0052 16.6 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PE PF00934.20 KXX76820.1 - 0.14 12.5 0.7 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 PE family Peroxidase_2 PF01328.17 KXX76821.1 - 3.6e-43 148.3 0.0 4.5e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 BLM10_N PF16547.5 KXX76821.1 - 0.052 13.8 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal LAMTOR PF15454.6 KXX76821.1 - 0.19 12.3 0.2 1 10.0 0.0 2.0 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ATX_III PF08098.11 KXX76823.1 - 0.04 13.9 0.5 0.09 12.8 0.5 1.5 1 0 0 1 1 1 0 Anemonia sulcata toxin III family RNA_helicase PF00910.22 KXX76823.1 - 0.21 12.0 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase 2-Hacid_dh_C PF02826.19 KXX76824.1 - 1.2e-25 89.9 0.1 8.8e-13 48.0 0.0 3.5 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXX76824.1 - 0.14 12.7 0.0 0.52 10.9 0.0 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_11 PF00457.17 KXX76825.1 - 9.8e-68 227.3 10.8 1.1e-67 227.1 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DAO PF01266.24 KXX76826.1 - 0.015 14.9 0.2 0.028 14.0 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX76826.1 - 0.023 14.9 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX76826.1 - 0.11 11.8 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.18 KXX76827.1 - 8.9e-14 51.2 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFA PF04828.14 KXX76828.1 - 3.7e-15 56.0 0.7 5.8e-15 55.4 0.7 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KXX76828.1 - 0.0005 19.9 0.7 0.0005 19.9 0.7 2.4 3 0 0 3 3 3 1 Nudix N-terminal DUF1857 PF08982.11 KXX76830.1 - 8.2e-55 184.7 0.2 9.9e-55 184.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) ArgoN PF16486.5 KXX76831.1 - 5e-19 69.3 0.1 7.7e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXX76831.1 - 1.9e-13 49.8 0.2 3.3e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 Argonaute linker 1 domain Herpes_UL14 PF03580.14 KXX76831.1 - 0.097 12.9 1.2 0.29 11.4 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Piwi PF02171.17 KXX76832.1 - 1.5e-77 260.8 0.0 2.8e-77 260.0 0.0 1.4 1 1 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 KXX76832.1 - 2.1e-10 40.8 0.1 5e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KXX76832.1 - 9.1e-10 38.5 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KXX76832.1 - 0.0053 17.0 0.0 0.016 15.5 0.0 1.8 2 0 0 2 2 2 1 Mid domain of argonaute NmrA PF05368.13 KXX76833.1 - 1.2e-12 47.9 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX76833.1 - 2.8e-11 43.7 0.0 5.6e-11 42.7 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXX76833.1 - 8e-08 32.0 0.1 5.6e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXX76833.1 - 0.0039 17.1 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KXX76833.1 - 0.0069 17.0 0.1 0.012 16.1 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 KXX76833.1 - 0.0082 15.3 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXX76833.1 - 0.018 14.2 0.1 0.026 13.6 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXX76833.1 - 0.032 14.5 0.2 0.057 13.7 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXX76833.1 - 0.078 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KXX76833.1 - 0.13 11.2 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXX76833.1 - 0.21 10.9 0.1 0.43 9.9 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Flavokinase PF01687.17 KXX76834.1 - 1.9e-35 121.5 0.0 2.7e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase PAP1 PF08601.10 KXX76835.1 - 1.5e-68 232.2 41.0 2.7e-43 149.1 0.9 3.2 2 1 1 3 3 3 3 Transcription factor PAP1 bZIP_1 PF00170.21 KXX76835.1 - 1.1e-08 35.0 13.1 2.6e-08 33.8 13.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXX76835.1 - 0.0075 16.3 15.8 0.027 14.6 15.8 1.9 1 1 0 1 1 1 1 Basic region leucine zipper SHE3 PF17078.5 KXX76835.1 - 0.036 13.8 6.4 0.06 13.1 6.4 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 dsrm PF00035.26 KXX76835.1 - 0.091 13.5 0.2 0.26 12.0 0.2 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif Lebercilin PF15619.6 KXX76835.1 - 0.1 12.3 11.7 0.17 11.6 11.7 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_Maf PF03131.17 KXX76835.1 - 0.17 12.4 9.7 0.38 11.3 9.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor EMP24_GP25L PF01105.24 KXX76835.1 - 0.22 11.4 1.5 0.42 10.5 1.5 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Baculo_gp64 PF03273.13 KXX76835.1 - 0.26 10.1 0.3 0.36 9.6 0.3 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family SlyX PF04102.12 KXX76835.1 - 0.37 11.4 2.7 1 10.0 2.7 1.8 1 0 0 1 1 1 0 SlyX DUF16 PF01519.16 KXX76835.1 - 0.4 11.2 4.3 0.81 10.2 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF812 PF05667.11 KXX76835.1 - 0.55 9.1 9.6 0.82 8.5 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 KXX76835.1 - 2 8.5 7.5 3 7.9 7.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PV-1 PF06637.11 KXX76835.1 - 2.9 6.6 8.5 5.5 5.7 8.5 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CDC45 PF02724.14 KXX76835.1 - 5.3 5.2 10.5 8.5 4.5 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KXX76836.1 - 1.5e-60 204.8 0.0 2e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76836.1 - 1.3e-30 106.6 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX76836.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXX76836.1 - 0.0044 15.8 0.7 0.032 13.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXX76836.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX76836.1 - 0.03 14.2 0.3 0.03 14.2 0.3 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Methyltransf_23 PF13489.6 KXX76837.1 - 3.7e-18 65.9 0.0 5.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX76837.1 - 2.8e-15 56.7 0.1 4.6e-14 52.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX76837.1 - 1.4e-13 51.4 0.0 2.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX76837.1 - 4.4e-12 46.5 0.0 1.1e-11 45.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX76837.1 - 7e-11 42.1 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXX76837.1 - 0.00031 20.2 0.0 0.0014 18.1 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXX76837.1 - 0.0056 16.2 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KXX76837.1 - 0.012 15.0 0.0 0.78 9.0 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Peptidase_S80 PF07230.11 KXX76838.1 - 0.12 10.7 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) HMG_CoA_synt_C PF08540.10 KXX76839.1 - 1.2e-101 340.1 0.1 1.8e-101 339.5 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXX76839.1 - 1.5e-96 321.3 0.5 2.4e-96 320.6 0.5 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal BCS1_N PF08740.11 KXX76840.1 - 1.6e-54 184.7 3.0 1.6e-54 184.7 3.0 2.9 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KXX76840.1 - 6.1e-17 62.3 0.0 2.3e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX76840.1 - 0.0025 17.6 0.0 0.0089 15.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXX76840.1 - 0.0054 16.7 0.0 0.025 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXX76840.1 - 0.0059 17.0 1.9 0.012 16.0 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KXX76840.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXX76840.1 - 0.095 13.0 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 KXX76840.1 - 0.12 10.9 23.2 0.19 10.3 23.2 1.4 1 0 0 1 1 1 0 Macoilin family AAA_11 PF13086.6 KXX76840.1 - 0.78 9.5 0.0 0.78 9.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain SLC12 PF03522.15 KXX76840.1 - 6.6 5.6 19.6 14 4.6 19.6 1.7 1 0 0 1 1 1 0 Solute carrier family 12 Anophelin PF10731.9 KXX76842.1 - 0.04 13.8 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Abhydrolase_3 PF07859.13 KXX76843.1 - 5.4e-38 131.0 0.1 1.1e-28 100.5 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXX76843.1 - 4.6e-14 52.1 0.0 5.4e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Steryl acetyl hydrolase SR-25 PF10500.9 KXX76843.1 - 0.0056 16.3 2.7 0.0056 16.3 2.7 2.7 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Coilin_N PF15862.5 KXX76843.1 - 0.0075 16.1 0.5 0.027 14.3 0.5 2.0 1 0 0 1 1 1 1 Coilin N-terminus COesterase PF00135.28 KXX76843.1 - 0.034 13.0 0.2 0.76 8.6 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family MRP-L27 PF09809.9 KXX76844.1 - 1.6e-19 69.8 0.4 2.1e-19 69.4 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.13 KXX76845.1 - 1.2e-197 659.0 57.2 1.2e-197 659.0 57.2 2.6 1 1 1 2 2 2 1 Utp14 protein WD40 PF00400.32 KXX76846.1 - 2e-54 180.3 10.8 4e-11 43.3 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat SesA PF17107.5 KXX76846.1 - 6.9e-41 139.3 0.2 7.7e-40 135.9 0.1 2.5 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ANAPC4_WD40 PF12894.7 KXX76846.1 - 4.7e-21 74.9 0.3 0.00017 21.8 0.0 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXX76846.1 - 5.5e-18 65.4 0.1 1.4e-17 64.1 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KXX76846.1 - 9.3e-12 44.5 0.3 0.1 11.5 0.0 4.8 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXX76846.1 - 3.7e-05 23.6 9.1 4.5 7.3 0.2 4.7 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.11 KXX76846.1 - 6.6e-05 21.9 0.1 0.07 12.0 0.0 2.9 1 1 1 3 3 3 3 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.8 KXX76846.1 - 8.1e-05 21.5 2.4 4.1 5.9 0.0 4.5 2 1 3 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KXX76846.1 - 0.0002 20.8 0.0 0.99 8.7 0.0 3.2 1 1 3 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 KXX76846.1 - 0.0031 17.1 4.1 0.0066 16.1 1.6 2.1 1 1 2 3 3 3 2 PQQ-like domain AAA_16 PF13191.6 KXX76846.1 - 0.0038 17.6 0.1 0.013 15.9 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain Gal4_dimer PF03902.13 KXX76846.1 - 0.0059 16.7 0.0 0.044 13.9 0.0 2.5 3 0 0 3 3 3 1 Gal4-like dimerisation domain PIF1 PF05970.14 KXX76846.1 - 0.1 11.8 0.2 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AAA_19 PF13245.6 KXX76846.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DHBP_synthase PF00926.19 KXX76847.1 - 6.4e-85 283.5 0.0 7.4e-85 283.3 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase BSD PF03909.17 KXX76848.1 - 6.1e-20 71.0 0.0 1.3e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 BSD domain BSP_II PF05432.11 KXX76848.1 - 3e-05 23.9 9.8 3e-05 23.9 9.8 2.3 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Suf PF05843.14 KXX76848.1 - 0.012 15.7 0.7 0.012 15.7 0.7 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ORC6 PF05460.13 KXX76848.1 - 0.013 14.8 1.7 0.013 14.8 1.7 2.5 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) TPR_2 PF07719.17 KXX76848.1 - 0.071 13.3 0.5 0.44 10.8 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_r2 PF04542.14 KXX76848.1 - 0.13 12.0 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 Sigma-70 region 2 RR_TM4-6 PF06459.12 KXX76848.1 - 0.16 11.8 11.5 0.11 12.4 2.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 KXX76848.1 - 0.29 11.2 6.8 0.65 10.1 1.3 2.3 2 0 0 2 2 2 0 DDHD domain RXT2_N PF08595.11 KXX76848.1 - 1.9 8.5 7.2 0.43 10.6 2.4 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal WGG PF10273.9 KXX76849.1 - 1.1e-36 125.3 0.6 2e-36 124.5 0.6 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KXX76849.1 - 0.0092 16.1 0.2 0.0092 16.1 0.2 2.3 2 1 1 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Epimerase PF01370.21 KXX76850.1 - 4e-10 39.6 0.0 1.3e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX76850.1 - 1.3e-09 38.2 0.1 2.4e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 KXX76850.1 - 4.5e-08 32.8 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 HIM1 NmrA PF05368.13 KXX76850.1 - 3.2e-05 23.6 0.1 7.8e-05 22.3 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KXX76850.1 - 0.003 16.8 0.0 0.83 8.8 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.24 KXX76850.1 - 0.031 14.7 0.0 0.056 13.9 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXX76850.1 - 0.094 11.7 0.0 0.66 8.9 0.0 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PAS PF00989.25 KXX76851.1 - 0.00088 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KXX76851.1 - 0.0018 18.3 8.6 0.0047 17.0 8.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transformer PF06495.11 KXX76851.1 - 3 7.9 10.0 13 5.8 10.0 2.0 1 1 0 1 1 1 0 Fruit fly transformer protein MFS_1 PF07690.16 KXX76852.1 - 7.9e-35 120.4 25.1 7.9e-35 120.4 25.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX76852.1 - 7e-06 24.7 3.1 1.1e-05 24.1 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transket_pyr PF02779.24 KXX76853.1 - 2.3e-43 147.9 0.0 4.6e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXX76853.1 - 6.1e-33 113.3 0.1 1.2e-32 112.4 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KXX76853.1 - 0.00065 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Cellulase PF00150.18 KXX76854.1 - 1.5e-10 41.0 0.1 2.8e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MULE PF10551.9 KXX76855.1 - 6.9e-16 58.4 0.0 1.8e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 KXX76855.1 - 0.00018 20.5 0.4 0.00018 20.5 0.4 1.7 2 1 0 2 2 2 1 Transposase, Mutator family DUF2121 PF09894.9 KXX76855.1 - 0.051 13.1 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) zf-RING_2 PF13639.6 KXX76856.1 - 2e-10 40.9 2.6 2.9e-10 40.3 2.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXX76856.1 - 4e-06 27.0 4.0 1.6e-05 25.1 4.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXX76856.1 - 4.2e-05 23.5 0.3 7e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KXX76856.1 - 4.5e-05 23.2 2.5 8.2e-05 22.4 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX76856.1 - 0.00013 21.9 2.3 0.00026 21.0 2.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXX76856.1 - 0.00024 20.9 0.9 0.00048 19.9 0.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX76856.1 - 0.0014 18.5 0.8 0.0022 17.8 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXX76856.1 - 0.01 15.7 2.7 0.62 10.0 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXX76856.1 - 0.061 13.3 0.7 0.14 12.2 0.7 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KXX76856.1 - 0.069 13.0 3.7 0.24 11.2 3.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KXX76856.1 - 0.073 12.8 2.0 0.089 12.6 0.6 1.8 2 0 0 2 2 2 0 RING-like zinc finger Zn-C2H2_12 PF18112.1 KXX76856.1 - 0.075 13.5 3.7 1.8 9.1 0.1 2.9 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_5 PF17121.5 KXX76856.1 - 0.076 12.9 5.3 0.61 10.0 5.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 KXX76856.1 - 0.11 12.8 0.8 18 5.7 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 KXX76856.1 - 0.16 11.8 2.4 0.65 9.9 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.8 KXX76856.1 - 0.17 12.1 1.7 2.9 8.1 1.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Sec39 PF08314.11 KXX76857.1 - 9.8e-285 946.8 0.0 1.2e-284 946.5 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ribosomal_60s PF00428.19 KXX76859.1 - 1.2e-26 93.1 9.3 1.4e-26 92.9 9.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KXX76859.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain Prog_receptor PF02161.15 KXX76859.1 - 0.053 12.2 3.0 0.057 12.2 3.0 1.0 1 0 0 1 1 1 0 Progesterone receptor Phage-MuB_C PF09077.11 KXX76859.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Mu B transposition protein, C terminal Pkinase PF00069.25 KXX76860.1 - 6.8e-45 153.5 0.0 6.4e-32 110.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76860.1 - 3.6e-20 72.3 0.0 2.5e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXX76860.1 - 2.8e-06 27.5 0.2 0.014 15.3 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KXX76860.1 - 0.047 13.3 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Ribosomal_S8e PF01201.22 KXX76861.1 - 2.6e-32 111.8 1.6 6.4e-31 107.3 1.7 2.3 1 1 0 1 1 1 1 Ribosomal protein S8e Bud13 PF09736.9 KXX76861.1 - 4.7 7.6 12.0 9.2 6.7 12.0 1.6 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Tim17 PF02466.19 KXX76862.1 - 1e-14 54.8 0.9 1.6e-14 54.2 0.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 KXX76862.1 - 0.02 15.1 2.0 1.9 8.7 0.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5518) Pyr_redox_2 PF07992.14 KXX76863.1 - 0.0083 15.4 0.2 0.3 10.3 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase zf-RING_5 PF14634.6 KXX76864.1 - 0.0023 17.9 10.4 0.0023 17.9 10.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain IBR PF01485.21 KXX76864.1 - 0.0032 17.6 0.6 0.0032 17.6 0.6 2.7 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXX76864.1 - 9.8 6.1 17.6 1.2 9.1 8.5 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DIOX_N PF14226.6 KXX76865.1 - 2.8e-19 70.0 0.0 4.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXX76865.1 - 5.5e-13 49.3 0.0 1.1e-11 45.1 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GCD14 PF08704.10 KXX76866.1 - 4.5e-64 216.5 0.0 2.2e-46 158.5 0.0 2.8 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Glyco_hydro_31 PF01055.26 KXX76867.1 - 9.2e-142 473.3 4.4 1.3e-141 472.8 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXX76867.1 - 2.5e-25 88.6 0.5 1e-23 83.4 0.2 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXX76867.1 - 2.9e-07 30.7 0.9 1.9e-06 28.0 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Peptidase_A4 PF01828.17 KXX76868.1 - 2.3e-34 118.7 2.3 4.4e-33 114.5 2.3 2.0 1 1 0 1 1 1 1 Peptidase A4 family T7SS_ESX_EspC PF10824.8 KXX76869.1 - 0.015 15.8 1.2 0.015 15.8 1.2 1.9 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm NDK PF00334.19 KXX76870.1 - 1.3e-53 180.6 0.0 1.5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase zf-C2H2 PF00096.26 KXX76871.1 - 0.00019 21.7 19.0 0.00078 19.8 0.7 5.1 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 KXX76871.1 - 0.0071 16.6 0.3 2 8.8 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KXX76871.1 - 0.057 13.4 0.1 0.057 13.4 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger UPF0175 PF03683.13 KXX76871.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) zf-C2H2_4 PF13894.6 KXX76871.1 - 0.14 13.0 0.4 0.14 13.0 0.4 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KXX76871.1 - 0.21 12.2 0.0 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain ELO PF01151.18 KXX76872.1 - 8.9e-08 32.0 1.8 1.8e-07 30.9 1.8 1.6 1 1 0 1 1 1 1 GNS1/SUR4 family WSC PF01822.19 KXX76873.1 - 3.3e-72 238.7 63.1 9.6e-19 67.4 6.6 4.1 4 0 0 4 4 4 4 WSC domain Toxin_35 PF10530.9 KXX76873.1 - 0.25 11.3 19.7 1.9 8.5 0.9 4.7 4 0 0 4 4 4 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold MS_channel PF00924.18 KXX76875.1 - 2e-20 73.2 2.6 3.7e-20 72.3 2.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KXX76875.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KXX76875.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KXX76875.1 - 0.19 11.3 0.3 0.48 10.1 0.3 1.7 1 0 0 1 1 1 0 EF hand SPT2 PF08243.11 KXX76876.1 - 6.7e-10 39.5 29.8 6.7e-10 39.5 29.8 2.9 2 1 0 2 2 2 1 SPT2 chromatin protein IBR PF01485.21 KXX76877.1 - 0.00011 22.4 9.1 0.00034 20.8 3.7 2.3 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KXX76877.1 - 0.006 16.6 4.6 0.006 16.6 4.6 2.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXX76877.1 - 0.0095 16.2 2.6 0.0095 16.2 2.6 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXX76877.1 - 0.029 14.5 0.4 0.029 14.5 0.4 2.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KXX76877.1 - 0.029 14.2 1.8 0.029 14.2 1.8 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX76877.1 - 0.035 13.9 0.9 0.035 13.9 0.9 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX76877.1 - 0.036 14.0 5.0 0.036 14.0 5.0 2.8 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KXX76877.1 - 2.5 8.0 12.1 0.057 13.3 2.9 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KXX76877.1 - 8.3 6.6 11.6 3 8.1 1.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger Pkinase PF00069.25 KXX76878.1 - 1.1e-50 172.4 0.0 3.3e-50 170.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX76878.1 - 8.6e-20 71.1 0.0 4.8e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXX76878.1 - 0.11 12.1 0.1 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KXX76878.1 - 0.14 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mtc PF03820.17 KXX76879.1 - 1.7e-120 401.8 0.0 1.9e-120 401.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Lactamase_B_4 PF13691.6 KXX76880.1 - 2.8e-27 94.2 0.1 1.1e-26 92.3 0.0 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KXX76880.1 - 2e-13 50.3 0.1 9.6e-13 48.1 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXX76880.1 - 0.0014 18.6 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily EB1 PF03271.17 KXX76881.1 - 7.6e-17 61.3 2.1 1.6e-16 60.2 2.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KXX76881.1 - 0.001 19.2 0.2 0.0026 17.9 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain PX PF00787.24 KXX76882.1 - 7.8e-15 54.9 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 PX domain DUF4020 PF13212.6 KXX76882.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) HET PF06985.11 KXX76884.1 - 8.7e-07 29.4 0.0 0.00057 20.3 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 KXX76885.1 - 7.5e-68 229.1 0.0 3e-28 98.6 0.1 3.9 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 KXX76885.1 - 8.1e-11 42.7 0.1 2.4e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 KXX76885.1 - 0.0045 17.0 0.7 0.011 15.7 0.7 1.6 1 0 0 1 1 1 1 Gas vesicle protein G DUF2183 PF09949.9 KXX76887.1 - 2.9e-31 107.7 0.0 6.4e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KXX76887.1 - 0.055 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DEAD PF00270.29 KXX76889.1 - 9.3e-47 159.1 0.9 1.7e-46 158.2 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX76889.1 - 8.8e-29 100.1 0.4 8.7e-28 96.9 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KXX76889.1 - 0.019 13.7 1.1 0.15 10.8 0.1 2.8 1 1 2 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Glyco_hydro_16 PF00722.21 KXX76891.1 - 2.4e-06 27.2 0.0 4.7e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Flavin_Reduct PF01613.18 KXX76892.1 - 5.7e-16 58.9 0.1 8e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.15 KXX76893.1 - 2.6e-50 171.5 0.0 1.1e-22 80.6 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Med10 PF09748.9 KXX76894.1 - 0.095 12.7 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex p450 PF00067.22 KXX76897.1 - 3.3e-22 78.9 0.3 2e-21 76.3 0.1 2.2 2 1 0 2 2 2 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 KXX76898.1 - 1e-59 201.9 0.0 1.2e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.11 KXX76900.1 - 5.6e-17 62.4 0.0 6.5e-14 52.5 0.0 3.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_holin_4_1 PF05105.12 KXX76901.1 - 0.056 13.6 1.4 0.062 13.4 1.4 1.1 1 0 0 1 1 1 0 Bacteriophage holin family adh_short PF00106.25 KXX76903.1 - 4.4e-30 104.6 0.0 6.3e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX76903.1 - 2.6e-21 76.2 0.0 3.5e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX76903.1 - 1.3e-08 34.9 0.1 2e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXX76903.1 - 3e-06 26.8 0.0 0.00011 21.7 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXX76903.1 - 5.4e-05 22.8 0.0 0.00011 21.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX76903.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding PNP_UDP_1 PF01048.20 KXX76904.1 - 0.11 11.8 0.1 0.47 9.7 0.0 1.9 2 0 0 2 2 2 0 Phosphorylase superfamily HET PF06985.11 KXX76905.1 - 1.3e-08 35.3 8.4 2.8e-07 31.0 1.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF5589 PF17672.1 KXX76905.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5589) Ank_4 PF13637.6 KXX76906.1 - 6.9e-06 26.5 0.0 1.2e-05 25.8 0.0 1.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX76906.1 - 7.4e-06 26.5 0.1 1.4e-05 25.6 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX76906.1 - 5.6e-05 23.2 0.0 0.00026 21.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXX76906.1 - 0.00021 21.6 0.1 0.00059 20.2 0.0 1.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXX76906.1 - 0.00022 21.5 0.0 0.0003 21.0 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) p450 PF00067.22 KXX76907.1 - 2.4e-29 102.4 0.0 3.2e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KXX76908.1 - 8.9e-25 87.0 0.7 1.4e-24 86.4 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2573 PF10835.8 KXX76909.1 - 0.16 12.3 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) Epimerase PF01370.21 KXX76910.1 - 5.5e-11 42.4 0.1 3.6e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX76910.1 - 5e-05 23.3 0.1 0.00022 21.2 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXX76910.1 - 0.00065 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KXX76910.1 - 0.0046 16.2 0.1 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein MMR_HSR1 PF01926.23 KXX76913.1 - 3.6e-06 27.0 0.5 0.00031 20.8 0.2 3.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KXX76913.1 - 8.2e-05 22.0 0.0 0.2 11.0 0.0 2.7 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 KXX76913.1 - 0.00064 19.7 0.0 0.0028 17.6 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 KXX76913.1 - 0.0031 16.9 0.0 0.13 11.6 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KXX76913.1 - 0.0055 17.1 0.1 0.34 11.3 0.0 3.1 4 0 0 4 4 3 1 AAA ATPase domain AAA_29 PF13555.6 KXX76913.1 - 0.0056 16.4 0.0 0.035 13.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX76913.1 - 0.0091 16.3 0.0 0.25 11.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain Septin PF00735.18 KXX76913.1 - 0.021 14.1 0.1 0.085 12.1 0.1 2.0 1 1 0 1 1 1 0 Septin T2SSE PF00437.20 KXX76913.1 - 0.03 13.4 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 KXX76913.1 - 0.071 13.0 0.1 0.63 9.9 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KXX76913.1 - 0.11 13.1 0.0 0.57 10.7 0.0 2.2 1 0 0 1 1 1 0 ABC transporter CarD_CdnL_TRCF PF02559.16 KXX76913.1 - 0.14 12.9 1.4 1 10.1 0.0 3.1 4 0 0 4 4 2 0 CarD-like/TRCF domain DUF87 PF01935.17 KXX76913.1 - 0.26 11.4 4.6 1.6 8.8 0.0 3.6 3 1 0 3 3 3 0 Helicase HerA, central domain DUF3510 PF12022.8 KXX76913.1 - 0.41 11.0 2.1 1.6 9.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) AAA_23 PF13476.6 KXX76913.1 - 3.7 8.0 9.9 1.3 9.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain ATG16 PF08614.11 KXX76913.1 - 6.9 6.8 13.8 2 8.6 0.6 3.4 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) MFS_1 PF07690.16 KXX76914.1 - 4.1e-40 137.8 27.5 4.1e-40 137.8 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXX76914.1 - 0.037 12.3 3.7 0.018 13.4 1.2 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MRP-L20 PF12824.7 KXX76915.1 - 1.7e-56 190.9 2.0 2.3e-56 190.5 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF1485 PF07364.12 KXX76916.1 - 0.032 13.5 0.1 0.056 12.7 0.1 1.4 1 0 0 1 1 1 0 Metallopeptidase family M81 PTR2 PF00854.21 KXX76917.1 - 1.1e-74 251.7 0.4 2.4e-74 250.5 0.5 1.4 2 0 0 2 2 2 1 POT family MFS_1 PF07690.16 KXX76917.1 - 3.2e-08 32.9 15.7 3.2e-08 32.9 15.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Mntp PF02659.15 KXX76917.1 - 0.22 11.3 6.2 0.89 9.3 0.0 3.1 3 1 0 3 3 3 0 Putative manganese efflux pump DUF3405 PF11885.8 KXX76918.1 - 1.9e-211 703.2 0.1 2.2e-211 703.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Trehalase PF01204.18 KXX76919.1 - 9.4e-198 658.2 0.0 1.1e-197 657.9 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KXX76919.1 - 2.5e-15 55.9 0.2 4.3e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GATase_6 PF13522.6 KXX76920.1 - 6.6e-15 55.5 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXX76920.1 - 1.1e-12 47.9 0.0 2.2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KXX76920.1 - 3e-06 26.8 0.0 6.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KXX76920.1 - 8.3e-05 21.6 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ICL PF00463.21 KXX76922.1 - 0 1011.1 0.5 0 1011.0 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXX76922.1 - 1.5e-11 44.3 0.0 2.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glyco_trans_2_3 PF13632.6 KXX76923.1 - 1.7e-50 171.7 1.9 1.7e-50 171.7 1.9 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXX76923.1 - 0.00032 20.6 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXX76923.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 21 TrbE PF11100.8 KXX76923.1 - 0.38 11.0 5.1 1.7 8.9 5.1 2.1 1 0 0 1 1 1 0 Conjugal transfer protein TrbE FYVE PF01363.21 KXX76924.1 - 0.0078 16.3 4.6 0.0078 16.3 4.6 3.1 3 1 0 3 3 3 1 FYVE zinc finger Sporozoite_P67 PF05642.11 KXX76924.1 - 0.077 11.1 7.4 0.12 10.4 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 KXX76924.1 - 0.19 11.7 10.0 0.44 10.5 10.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-B_box PF00643.24 KXX76924.1 - 4.1 7.6 10.4 1.8 8.8 1.5 3.1 3 0 0 3 3 3 0 B-box zinc finger p450 PF00067.22 KXX76925.1 - 9.5e-49 166.4 0.0 2.6e-48 164.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 PBP-Tp47_a PF14889.6 KXX76925.1 - 0.12 12.1 0.2 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a SNF2_N PF00176.23 KXX76926.1 - 1.2e-51 175.5 0.2 3.8e-51 173.9 0.2 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KXX76926.1 - 2.5e-26 91.6 0.8 2.5e-26 91.6 0.8 2.3 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KXX76926.1 - 7.3e-19 68.2 0.0 9.9e-18 64.5 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXX76926.1 - 4.4e-08 32.7 2.3 8.7e-07 28.4 0.0 2.4 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KXX76926.1 - 9.6e-07 29.0 0.0 6.3e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KXX76926.1 - 0.046 12.6 1.6 0.82 8.5 0.1 2.5 3 0 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 AidB_N PF18158.1 KXX76927.1 - 3.4e-15 56.3 0.0 7.6e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXX76927.1 - 1e-14 55.0 0.0 4.3e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXX76927.1 - 3.2e-11 43.3 0.0 8.6e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXX76927.1 - 0.00028 21.2 0.0 0.28 11.4 0.0 2.8 4 0 0 4 4 4 2 Acyl-CoA dehydrogenase, C-terminal domain OPT PF03169.15 KXX76928.1 - 1.1e-187 625.4 44.0 1.3e-187 625.2 44.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DHFR_1 PF00186.19 KXX76929.1 - 3.7e-26 91.7 0.0 4.1e-25 88.3 0.0 2.5 1 1 0 1 1 1 1 Dihydrofolate reductase Ubiq_cyt_C_chap PF03981.12 KXX76930.1 - 9.4e-36 123.0 3.2 3.6e-35 121.1 3.2 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone RIX1 PF08167.12 KXX76931.1 - 1.7e-60 204.0 1.6 7.5e-60 201.9 0.1 2.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF4746 PF15928.5 KXX76931.1 - 1.6 8.1 4.5 2.3 7.6 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TPR_14 PF13428.6 KXX76932.1 - 8.2e-08 32.5 25.7 0.015 16.0 0.6 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX76932.1 - 2.5e-07 30.3 17.9 0.7 10.1 0.2 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX76932.1 - 0.00047 20.8 28.9 0.11 13.2 0.0 7.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX76932.1 - 0.00084 19.8 10.5 0.029 14.9 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX76932.1 - 0.0092 15.8 8.1 13 5.8 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXX76932.1 - 0.01 16.0 10.0 1.4 9.1 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXX76932.1 - 0.021 15.2 3.0 4.4 7.9 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXX76932.1 - 0.17 12.0 12.4 13 6.1 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX76932.1 - 1.1 9.6 8.4 6.8 7.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Cutinase PF01083.22 KXX76934.1 - 9.9e-43 146.2 0.2 1.1e-42 145.9 0.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXX76934.1 - 0.025 14.1 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 PE-PPE domain HET PF06985.11 KXX76935.1 - 2.8e-18 66.7 0.7 6.4e-18 65.5 0.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Dus PF01207.17 KXX76936.1 - 4.8e-60 203.3 0.0 8.1e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KXX76936.1 - 0.041 13.1 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Chisel PF15355.6 KXX76936.1 - 0.17 12.1 1.5 2.8 8.2 0.3 2.6 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel DUF3895 PF13034.6 KXX76936.1 - 0.21 11.6 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Glyco_hydro_16 PF00722.21 KXX76937.1 - 4.4e-11 42.6 1.9 6.3e-11 42.1 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Prok-E2_E PF14462.6 KXX76937.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E WW PF00397.26 KXX76938.1 - 0.35 11.0 5.7 1.2 9.3 5.7 1.9 1 0 0 1 1 1 0 WW domain DUF3439 PF11921.8 KXX76938.1 - 4.6 7.2 11.1 0.27 11.2 5.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SnoaL_2 PF12680.7 KXX76939.1 - 0.002 18.7 0.9 0.0037 17.9 0.8 1.5 1 1 0 1 1 1 1 SnoaL-like domain Bactofilin PF04519.13 KXX76941.1 - 7.7e-09 35.7 0.9 6.8e-08 32.7 0.3 2.1 1 1 1 2 2 2 1 Polymer-forming cytoskeletal FapA PF03961.13 KXX76941.1 - 0.00023 19.9 2.3 0.00066 18.4 2.3 1.5 1 1 0 1 1 1 1 Flagellar Assembly Protein A Chorion_1 PF01723.16 KXX76941.1 - 0.01 15.8 1.9 1.2 9.1 0.3 2.8 1 1 2 3 3 3 0 Chorion protein SpoVG PF04026.12 KXX76941.1 - 0.023 14.9 0.1 0.33 11.2 0.0 2.5 1 1 1 2 2 2 0 SpoVG MinC_C PF03775.16 KXX76941.1 - 0.03 14.3 0.2 11 6.1 0.0 2.5 1 1 1 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain ERbeta_N PF12497.8 KXX76941.1 - 0.099 12.4 3.5 4.1 7.2 1.3 2.2 2 0 0 2 2 2 0 Estrogen receptor beta zf-C2H2 PF00096.26 KXX76942.1 - 0.014 15.8 3.3 0.042 14.3 3.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX76942.1 - 0.23 11.9 1.6 8.3 7.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DPM2 PF07297.12 KXX76944.1 - 5.8e-34 116.2 1.8 6.7e-34 116.0 1.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KXX76944.1 - 8.4e-05 22.5 0.8 9.5e-05 22.3 0.8 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 KXX76944.1 - 0.00082 19.4 0.6 0.00082 19.4 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) LapA_dom PF06305.11 KXX76944.1 - 0.0091 15.8 0.3 0.0091 15.8 0.3 2.0 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain COX14 PF14880.6 KXX76944.1 - 0.025 14.4 2.5 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Phage_holin_3_6 PF07332.11 KXX76944.1 - 0.043 13.9 1.8 0.051 13.6 1.8 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ketoacyl-synt PF00109.26 KXX76945.1 - 6.3e-62 209.4 6.1 2.5e-60 204.2 0.6 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXX76945.1 - 1.6e-35 121.7 2.6 2.4e-35 121.1 1.8 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXX76945.1 - 2e-06 27.3 0.1 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX76945.1 - 0.0011 18.6 3.8 0.011 15.3 0.3 3.4 3 1 0 3 3 3 1 Thiolase, C-terminal domain DUF348 PF03990.14 KXX76945.1 - 0.012 15.3 0.2 1.4 8.8 0.4 2.8 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain KAsynt_C_assoc PF16197.5 KXX76945.1 - 0.16 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension PSI_PSAK PF01241.18 KXX76945.1 - 0.26 11.3 4.1 2.4 8.2 0.2 3.4 2 2 1 3 3 3 0 Photosystem I psaG / psaK Dioxygenase_C PF00775.21 KXX76946.1 - 2.3e-49 167.3 0.0 3.1e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXX76946.1 - 9.1e-26 89.5 0.2 1.4e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXX76946.1 - 1.5e-06 28.4 0.0 1e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.18 KXX76947.1 - 1.5e-24 86.5 0.0 2.7e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.29 KXX76948.1 - 1.6e-06 27.9 6.6 2.5e-06 27.3 6.6 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KXX76948.1 - 5.7e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KXX76948.1 - 0.19 12.0 0.5 0.36 11.1 0.5 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KXX76948.1 - 0.58 9.8 1.6 0.92 9.1 1.6 1.3 1 0 0 1 1 1 0 PHD-finger MA3 PF02847.17 KXX76949.1 - 6.9e-26 90.4 0.1 2.8e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KXX76949.1 - 6.4e-10 39.0 1.1 1.5e-09 37.8 1.1 1.7 1 0 0 1 1 1 1 MIF4G domain FAM176 PF14851.6 KXX76949.1 - 0.3 10.7 5.9 0.89 9.2 5.9 1.8 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 KXX76949.1 - 3.7 5.6 15.4 6.1 4.9 15.4 1.3 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_61 PF03443.14 KXX76950.1 - 1.7e-67 227.4 0.0 2.3e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 YTH PF04146.15 KXX76951.1 - 3e-32 111.9 0.8 3e-32 111.9 0.8 3.7 2 2 0 2 2 2 1 YT521-B-like domain zf-C2H2 PF00096.26 KXX76951.1 - 0.018 15.4 0.2 0.038 14.5 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX76951.1 - 0.026 15.3 0.1 0.062 14.2 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Velvet PF11754.8 KXX76952.1 - 3.1e-40 138.7 2.9 7.1e-31 108.0 0.2 2.7 2 2 1 3 3 3 2 Velvet factor DUF2456 PF10445.9 KXX76954.1 - 6.5e-11 42.2 2.0 6.5e-11 42.2 2.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) Mannosyl_trans2 PF04188.13 KXX76955.1 - 3.5e-55 188.1 2.4 1.2e-54 186.3 2.4 1.8 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF3311 PF11755.8 KXX76955.1 - 0.5 10.4 6.9 0.28 11.1 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Glyco_hydro_2_C PF02836.17 KXX76956.1 - 5.5e-104 347.5 0.2 4.4e-103 344.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXX76956.1 - 1.1e-57 195.4 0.0 1.9e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXX76956.1 - 8.1e-38 130.0 0.1 2e-37 128.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KXX76956.1 - 1.3e-13 51.2 0.0 8.3e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KXX76956.1 - 1.6e-11 44.9 0.0 3.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Hira PF07569.11 KXX76958.1 - 1.9e-84 282.8 0.0 4e-84 281.8 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KXX76958.1 - 5.6e-29 99.8 24.3 1.2e-05 25.9 0.1 8.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX76958.1 - 2.1e-15 56.8 0.1 0.033 14.5 0.1 6.3 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KXX76958.1 - 7.3e-11 41.6 0.5 1.6e-10 40.6 0.5 1.6 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 KXX76958.1 - 2e-06 27.0 0.8 0.03 13.3 0.0 4.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXX76958.1 - 3.3e-05 23.7 0.4 15 5.7 0.0 4.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KXX76958.1 - 0.089 12.1 0.0 22 4.2 0.0 3.3 4 0 0 4 4 4 0 WD40-like domain Rav1p_C PF12234.8 KXX76958.1 - 0.14 10.5 0.3 1.4 7.2 0.0 2.0 2 0 0 2 2 2 0 RAVE protein 1 C terminal Sortilin-Vps10 PF15902.5 KXX76959.1 - 6.2e-17 61.5 6.0 0.0033 16.3 0.0 7.5 4 2 3 8 8 8 5 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 KXX76959.1 - 4.6e-11 42.5 11.2 1.1e-10 41.2 11.2 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.20 KXX76959.1 - 0.00023 20.7 37.0 0.76 10.0 0.7 9.5 11 0 0 11 11 11 4 BNR/Asp-box repeat BNR_6 PF15899.5 KXX76959.1 - 0.016 15.2 5.0 13 6.2 0.0 6.3 8 0 0 8 8 8 0 BNR-Asp box repeat Acetyltransf_1 PF00583.25 KXX76960.1 - 3.2e-05 24.1 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX76960.1 - 0.0013 18.6 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX76960.1 - 0.0027 18.1 0.0 0.0039 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DEAD PF00270.29 KXX76962.1 - 3.4e-44 150.7 0.1 6.7e-44 149.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX76962.1 - 3.2e-28 98.3 0.0 1.2e-27 96.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX76962.1 - 5.5e-07 29.7 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KXX76962.1 - 0.005 15.7 0.0 0.079 11.7 0.0 2.1 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 4HBT_3 PF13622.6 KXX76962.1 - 0.051 13.8 0.1 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Thioesterase-like superfamily FtsJ PF01728.19 KXX76963.1 - 1.4e-63 214.2 0.0 1.8e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Zip PF02535.22 KXX76964.1 - 1.3e-34 119.9 27.7 1.7e-13 50.5 6.4 3.4 2 1 1 3 3 3 3 ZIP Zinc transporter Thyroglobulin_1 PF00086.18 KXX76964.1 - 2.7 7.7 4.8 6.7 6.5 0.1 2.7 3 0 0 3 3 3 0 Thyroglobulin type-1 repeat N2227 PF07942.12 KXX76965.1 - 1.5e-62 211.2 0.0 3.3e-62 210.2 0.0 1.5 1 1 1 2 2 2 1 N2227-like protein Methyltransf_11 PF08241.12 KXX76965.1 - 2.2e-07 31.4 0.0 1.1e-06 29.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX76965.1 - 0.0014 19.3 0.0 0.0083 16.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX76965.1 - 0.0024 18.5 0.3 0.027 15.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX76965.1 - 0.0084 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX76965.1 - 0.069 13.0 0.0 0.81 9.5 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DUF5536 PF17688.1 KXX76965.1 - 0.082 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5536) NAD_binding_8 PF13450.6 KXX76967.1 - 1.7e-15 57.0 0.1 5.2e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXX76967.1 - 1.2e-07 31.4 0.1 2.5e-06 27.1 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXX76967.1 - 3.2e-05 22.8 0.6 4.6e-05 22.3 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXX76967.1 - 6.9e-05 22.1 2.0 0.00012 21.4 2.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXX76967.1 - 0.00013 21.5 0.5 0.00018 21.0 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXX76967.1 - 0.00041 20.1 2.1 0.00087 19.0 1.9 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX76967.1 - 0.00089 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXX76967.1 - 0.0037 16.5 0.4 0.0069 15.6 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX76967.1 - 0.015 15.3 0.9 0.029 14.4 0.2 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXX76967.1 - 0.031 13.5 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX76967.1 - 0.041 13.1 0.6 0.068 12.4 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXX76967.1 - 0.041 14.4 0.2 0.082 13.5 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PHO4 PF01384.20 KXX76968.1 - 1.2e-112 376.3 17.0 1.4e-112 376.1 17.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.16 KXX76971.1 - 1.3e-33 116.4 43.6 1.3e-33 116.4 43.6 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX76971.1 - 3.2e-11 42.8 9.3 3.2e-11 42.8 9.3 2.4 3 1 0 3 3 3 1 Sugar (and other) transporter p450 PF00067.22 KXX76972.1 - 2e-50 171.9 0.0 2e-34 119.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Peptidase_S8 PF00082.22 KXX76973.1 - 3.4e-35 121.8 12.7 8.3e-35 120.5 12.7 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXX76973.1 - 0.0014 19.2 0.0 0.004 17.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 Defensin_3 PF08131.11 KXX76974.1 - 0.17 12.1 0.3 0.17 12.1 0.3 2.2 3 0 0 3 3 3 0 Defensin-like peptide family Hydrophobin PF01185.18 KXX76974.1 - 0.73 10.5 9.2 2.2 9.0 5.3 2.1 1 1 1 2 2 2 0 Fungal hydrophobin SGL PF08450.12 KXX76975.1 - 0.0088 15.7 0.0 0.27 10.8 0.0 2.8 2 2 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region DUF4115 PF13464.6 KXX76975.1 - 0.051 13.8 0.9 2.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) FAD_binding_3 PF01494.19 KXX76977.1 - 1.9e-14 53.7 0.3 4.9e-14 52.3 0.3 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX76977.1 - 0.00035 20.7 1.0 0.001 19.3 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KXX76977.1 - 0.0079 15.3 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KXX76977.1 - 0.0096 15.0 0.2 0.047 12.7 0.5 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX76977.1 - 0.013 14.8 0.7 0.021 14.0 0.7 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX76977.1 - 0.018 14.3 0.2 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXX76977.1 - 0.025 14.6 0.4 0.05 13.6 0.4 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 KXX76977.1 - 0.034 13.7 4.1 0.048 13.2 2.5 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX76977.1 - 2.7 7.0 6.9 0.87 8.6 4.1 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KXX76978.1 - 2.1e-20 73.2 0.1 1.2e-17 64.1 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX76978.1 - 5.6e-20 71.8 0.0 5.9e-17 61.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXX76978.1 - 9.7e-13 47.4 1.8 3.2e-12 45.7 0.3 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXX76978.1 - 9.8e-13 48.0 0.1 6.9e-10 38.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXX76978.1 - 8e-05 23.1 0.5 0.081 13.5 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX76978.1 - 0.00012 21.4 0.0 0.00096 18.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXX76978.1 - 0.0016 18.6 0.0 0.0083 16.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KXX76978.1 - 0.0055 16.1 0.1 0.028 13.8 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXX76978.1 - 0.015 15.4 0.0 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXX76978.1 - 0.018 15.0 2.6 6.5 6.7 0.0 3.6 3 1 1 4 4 4 0 FAD-NAD(P)-binding adh_short PF00106.25 KXX76978.1 - 0.036 13.5 0.0 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase 3HCDH_N PF02737.18 KXX76978.1 - 0.038 13.9 0.1 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KXX76978.1 - 0.039 12.7 1.6 0.77 8.4 0.1 3.2 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_2 PF00890.24 KXX76978.1 - 0.058 12.5 2.2 3.2 6.7 1.3 3.0 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.18 KXX76978.1 - 0.069 13.4 0.1 2.3 8.5 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain GIDA PF01134.22 KXX76978.1 - 0.077 12.1 2.6 12 4.9 0.1 3.4 4 0 0 4 4 4 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXX76978.1 - 0.15 11.1 0.1 0.38 9.7 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Thymidylat_synt PF00303.19 KXX76982.1 - 6.9e-107 356.5 0.0 8e-107 356.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase ketoacyl-synt PF00109.26 KXX76983.1 - 2.8e-78 263.0 0.0 5.8e-78 262.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX76983.1 - 3e-46 157.6 0.0 5.9e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXX76983.1 - 2.3e-45 155.1 0.0 3.6e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX76983.1 - 4.6e-45 154.5 0.0 9.1e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX76983.1 - 3.6e-30 104.4 0.1 8.1e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXX76983.1 - 4.6e-10 39.9 0.0 1.2e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXX76983.1 - 7.2e-10 38.7 0.0 1.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KXX76983.1 - 8.9e-07 29.2 0.1 1.6e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXX76983.1 - 0.0029 17.0 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Globin PF00042.22 KXX76984.1 - 2.2e-08 34.6 0.0 3.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KXX76984.1 - 5.4e-07 29.9 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXX76984.1 - 1.9e-06 28.5 0.0 3.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 KXX76984.1 - 0.012 15.6 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 Protoglobin Glycos_transf_1 PF00534.20 KXX76985.1 - 5.3e-23 81.4 0.0 1.5e-22 80.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXX76985.1 - 4.4e-15 56.3 0.0 7.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXX76985.1 - 0.00088 19.6 0.0 0.0023 18.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sec10 PF07393.11 KXX76986.1 - 2e-228 760.4 4.9 2.5e-228 760.1 4.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Ku_PK_bind PF08785.11 KXX76986.1 - 0.015 15.5 0.1 0.75 10.0 0.0 3.0 2 0 0 2 2 2 0 Ku C terminal domain like K_channel_TID PF07941.11 KXX76986.1 - 0.75 10.3 12.2 0.11 13.0 6.8 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Phage_Mu_Gam PF07352.12 KXX76986.1 - 1.9 8.4 6.0 1.8 8.4 0.5 3.2 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein DUF2415 PF10313.9 KXX76987.1 - 0.015 15.2 0.0 0.051 13.5 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KXX76987.1 - 0.63 11.0 2.4 6.7 7.8 0.2 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat SDA1 PF05285.12 KXX76987.1 - 5.1 6.4 21.8 0.12 11.8 14.7 1.8 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 KXX76987.1 - 7.1 5.8 21.5 0.16 11.3 15.0 1.4 2 0 0 2 2 2 0 BUD22 Chitin_synth_2 PF03142.15 KXX76989.1 - 1.7e-292 970.8 0.1 2.4e-292 970.2 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXX76989.1 - 5.8e-14 52.5 5.9 2.5e-13 50.4 5.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXX76989.1 - 3e-10 40.4 0.1 5.5e-09 36.3 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXX76989.1 - 0.0018 17.8 0.0 0.0094 15.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXX76989.1 - 0.033 14.0 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 MFS_2 PF13347.6 KXX76990.1 - 9.7e-10 37.6 11.3 9.7e-10 37.6 11.3 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KXX76990.1 - 7e-05 21.9 2.5 7e-05 21.9 2.5 1.8 2 0 0 2 2 2 1 MFS_1 like family UPF0114 PF03350.16 KXX76990.1 - 0.16 12.2 1.8 0.45 10.7 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 HisG PF01634.18 KXX76991.1 - 5.3e-56 189.0 0.0 7.4e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KXX76991.1 - 2.4e-29 101.3 0.3 5.3e-29 100.2 0.3 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain HLH PF00010.26 KXX76992.1 - 5.5e-16 58.3 0.0 1.2e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RE_AspBHI_N PF18062.1 KXX76992.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal DUF1917 PF08939.10 KXX76992.1 - 6 6.7 8.3 1.4 8.7 4.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) Proteasome PF00227.26 KXX76993.1 - 1.9e-48 164.5 0.3 2.3e-48 164.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Prenyltransf PF01255.19 KXX76994.1 - 5.9e-05 22.7 0.0 0.0064 16.0 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Met_10 PF02475.16 KXX76995.1 - 8.1e-76 254.2 0.0 1.1e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Gly_acyl_tr_N PF06021.11 KXX76995.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase RNB PF00773.19 KXX76996.1 - 1.3e-57 195.6 0.0 5.4e-57 193.6 0.0 2.0 2 1 0 2 2 2 1 RNB domain Sel1 PF08238.12 KXX76997.1 - 1.6e-40 136.6 28.7 6.3e-06 26.7 1.2 7.4 7 0 0 7 7 7 7 Sel1 repeat ANAPC3 PF12895.7 KXX76997.1 - 0.037 14.3 0.2 0.36 11.1 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MSC PF09402.10 KXX76998.1 - 1.1e-113 380.1 0.0 1.4e-113 379.8 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KXX76998.1 - 3.3e-18 65.1 0.8 1.4e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.11 KXX76998.1 - 1.4e-05 24.6 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein Peptidase_M22 PF00814.25 KXX76999.1 - 6e-47 160.6 0.0 2.7e-16 60.1 0.1 4.2 4 1 0 4 4 4 4 Glycoprotease family UPF0016 PF01169.19 KXX77000.1 - 0.18 12.2 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 DUF1752 PF08550.10 KXX77001.1 - 2.7e-10 39.9 5.3 2.7e-10 39.9 5.3 2.6 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1752) Spt5_N PF11942.8 KXX77001.1 - 0.037 15.0 5.6 4.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Voldacs PF03517.13 KXX77001.1 - 0.42 10.7 2.5 21 5.2 0.3 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling PBP1_TM PF14812.6 KXX77001.1 - 4.9 7.6 17.1 3.9 7.9 2.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPP4R2 PF09184.11 KXX77001.1 - 9.7 5.7 8.9 34 3.9 8.9 2.0 1 1 0 1 1 1 0 PPP4R2 ATPgrasp_N PF18130.1 KXX77002.1 - 4.5e-23 81.6 0.0 1.2e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KXX77002.1 - 1.1e-10 41.3 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXX77002.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KXX77002.1 - 0.036 14.1 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Esterase_phd PF10503.9 KXX77002.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Ferric_reduct PF01794.19 KXX77003.1 - 6.9e-21 74.7 16.6 2e-20 73.1 16.6 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXX77003.1 - 4.5e-05 23.6 0.0 0.44 10.7 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXX77003.1 - 0.0081 16.2 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KXX77003.1 - 0.02 15.5 0.0 0.12 13.0 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Hist_deacetyl PF00850.19 KXX77003.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain DUF4293 PF14126.6 KXX77003.1 - 8.6 6.6 10.6 0.94 9.7 5.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Methyltransf_31 PF13847.6 KXX77004.1 - 1.2e-21 77.1 0.0 2.7e-21 76.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77004.1 - 9.1e-16 58.4 0.0 1.1e-14 54.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77004.1 - 1.8e-12 47.7 0.0 5.1e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77004.1 - 4.6e-12 46.5 0.0 1.3e-11 45.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX77004.1 - 1.8e-09 37.6 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX77004.1 - 4.4e-07 29.5 0.0 9.1e-07 28.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXX77004.1 - 4.7e-06 26.0 0.0 7.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KXX77004.1 - 1.1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXX77004.1 - 4.4e-05 23.0 0.0 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KXX77004.1 - 0.00032 20.9 0.0 0.00045 20.4 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KXX77004.1 - 0.00056 19.3 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KXX77004.1 - 0.00098 18.8 0.0 0.0015 18.3 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 KXX77004.1 - 0.0014 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF1421 PF07223.11 KXX77004.1 - 0.0022 17.8 0.0 1.3 8.9 0.0 2.7 3 0 0 3 3 3 1 UBA-like domain (DUF1421) MetW PF07021.12 KXX77004.1 - 0.0023 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KXX77004.1 - 0.0043 17.1 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXX77004.1 - 0.0062 16.3 0.0 0.025 14.4 0.0 1.9 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 KXX77004.1 - 0.12 12.0 0.0 1.5 8.5 0.0 2.4 3 0 0 3 3 3 0 Putative RNA methylase family UPF0020 PTR2 PF00854.21 KXX77005.1 - 5e-52 177.1 1.7 8e-52 176.4 1.7 1.3 1 1 0 1 1 1 1 POT family GPI2 PF06432.11 KXX77005.1 - 0.092 12.2 0.2 0.092 12.2 0.2 1.9 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Aa_trans PF01490.18 KXX77006.1 - 5.7e-77 259.1 29.8 6.7e-77 258.9 29.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KXX77006.1 - 0.37 10.7 4.2 0.41 10.5 0.8 2.8 2 1 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Lyase_1 PF00206.20 KXX77007.1 - 1e-87 294.5 0.0 1.3e-87 294.1 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KXX77007.1 - 1.9e-22 79.8 0.2 6e-22 78.2 0.1 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal DUF1996 PF09362.10 KXX77008.1 - 5.4e-80 268.7 0.9 6.3e-80 268.5 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PALP PF00291.25 KXX77009.1 - 1.1e-28 100.5 0.0 5.9e-28 98.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 KXX77010.1 - 3.7e-38 131.4 0.0 1.5e-26 93.3 0.0 2.9 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family Formyl_trans_N PF00551.19 KXX77010.1 - 3e-24 85.8 0.0 5.1e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase GDP_Man_Dehyd PF16363.5 KXX77010.1 - 8.5e-22 78.0 0.0 1.6e-10 40.9 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Formyl_trans_C PF02911.18 KXX77010.1 - 1.4e-12 47.7 0.0 4.2e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain 3Beta_HSD PF01073.19 KXX77010.1 - 0.00066 18.8 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DegT_DnrJ_EryC1 PF01041.17 KXX77011.1 - 4.6e-104 348.6 0.0 5.2e-104 348.4 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXX77011.1 - 3.6e-05 23.1 0.0 5.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXX77011.1 - 0.0057 15.7 0.0 0.0071 15.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXX77011.1 - 0.054 12.8 0.1 0.081 12.2 0.1 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase TRP PF06011.12 KXX77012.1 - 3.8e-159 530.0 29.0 4.6e-159 529.7 29.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXX77012.1 - 3.4e-42 144.1 0.1 5.8e-42 143.4 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KXX77012.1 - 0.093 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 ML domain DUF4579 PF15158.6 KXX77012.1 - 0.41 10.4 3.1 0.83 9.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) DHHC PF01529.20 KXX77012.1 - 3.9 7.6 13.4 6.9 6.8 2.8 3.0 2 2 0 2 2 2 0 DHHC palmitoyltransferase Caudal_act PF04731.12 KXX77013.1 - 0.048 14.0 3.8 0.063 13.6 3.8 1.2 1 0 0 1 1 1 0 Caudal like protein activation region UCH PF00443.29 KXX77015.1 - 6.1e-34 117.7 0.0 8.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KXX77015.1 - 2.7e-25 87.9 1.8 1.4e-23 82.4 0.1 2.5 2 0 0 2 2 2 2 Variant UBP zinc finger zf-UBP PF02148.19 KXX77015.1 - 1.8e-22 79.4 17.3 2.7e-20 72.4 1.1 3.3 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KXX77015.1 - 1.9e-17 62.8 0.0 1.2e-09 37.9 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KXX77015.1 - 2.4e-16 60.2 1.3 3.2e-14 53.3 0.0 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase NifU_N PF01592.16 KXX77016.1 - 7.7e-55 184.5 0.0 9.8e-55 184.2 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1858 PF08984.11 KXX77016.1 - 0.081 13.1 0.1 0.28 11.4 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1858) TSCPD PF12637.7 KXX77016.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain adh_short PF00106.25 KXX77017.1 - 1e-38 132.8 0.0 1.3e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX77017.1 - 7e-28 97.8 0.0 9.1e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXX77017.1 - 4.3e-05 23.5 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding DUF1776 PF08643.10 KXX77017.1 - 0.0068 15.8 0.0 0.0087 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KXX77017.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 KR domain Ank_2 PF12796.7 KXX77018.1 - 6.2e-10 39.5 0.0 8.7e-07 29.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX77018.1 - 1.4e-07 31.6 5.3 0.88 10.1 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXX77018.1 - 3.3e-06 27.5 0.6 0.48 11.1 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77018.1 - 9.4e-05 22.5 4.6 1 10.2 0.1 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KXX77018.1 - 0.00033 20.9 0.5 0.47 10.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) HORMA PF02301.18 KXX77019.1 - 1.7e-29 103.0 0.0 2.2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain CAP_N PF01213.19 KXX77019.1 - 0.0015 18.1 0.7 0.002 17.7 0.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PP_M1 PF03012.14 KXX77019.1 - 0.024 14.2 0.2 0.031 13.8 0.2 1.2 1 0 0 1 1 1 0 Phosphoprotein ATG101 PF07855.12 KXX77019.1 - 0.034 14.1 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Autophagy-related protein 101 DUF2660 PF10859.8 KXX77019.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Beta-lactamase PF00144.24 KXX77020.1 - 2.7e-38 132.0 0.1 5.4e-38 131.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase RNase_H PF00075.24 KXX77023.1 - 1.4e-37 129.0 0.0 2.1e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KXX77023.1 - 1.5e-36 124.5 14.1 7.2e-19 67.8 3.3 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RVT_3 PF13456.6 KXX77023.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Peptidase_C14 PF00656.22 KXX77024.1 - 4.1e-57 194.0 0.0 5.7e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Clr5 PF14420.6 KXX77024.1 - 4e-19 68.6 1.3 9.4e-19 67.4 1.3 1.7 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.23 KXX77025.1 - 2.8e-56 190.7 0.0 5e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KXX77025.1 - 4e-26 90.7 2.2 8.1e-16 57.7 0.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KXX77025.1 - 7e-20 71.4 0.0 1.9e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KXX77025.1 - 1.3e-13 51.2 0.0 8e-13 48.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 KXX77025.1 - 7.5e-07 29.3 0.0 3.8e-06 27.0 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KXX77025.1 - 9.4e-07 29.2 0.4 9.4e-07 29.2 0.4 5.7 5 1 1 6 6 6 1 Chromodomain helicase DNA-binding domain 1 HDA2-3 PF11496.8 KXX77025.1 - 4.2e-06 26.1 0.0 4.2e-06 26.1 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SLIDE PF09111.10 KXX77025.1 - 0.0013 18.7 0.3 0.04 13.9 0.0 3.0 2 0 0 2 2 2 1 SLIDE POR PF01558.18 KXX77025.1 - 0.043 13.9 0.2 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase AAA_22 PF13401.6 KXX77025.1 - 0.058 13.7 0.0 0.25 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain SIR2 PF02146.17 KXX77026.1 - 8.1e-28 97.5 0.0 2.1e-27 96.2 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 KXX77026.1 - 0.085 13.0 2.3 0.18 12.0 2.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain FF PF01846.19 KXX77027.1 - 1.2e-52 175.9 5.6 1.3e-14 54.1 0.1 6.7 6 0 0 6 6 6 6 FF domain WW PF00397.26 KXX77027.1 - 2.1e-18 66.1 17.4 2.3e-10 40.4 3.3 2.8 2 0 0 2 2 2 2 WW domain ABC_tran PF00005.27 KXX77028.1 - 4.3e-34 118.0 0.0 3.4e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXX77028.1 - 8.7e-12 45.5 8.7 0.0064 16.3 0.1 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX77028.1 - 5.8e-09 35.7 2.2 0.023 14.2 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 KXX77028.1 - 5.2e-07 29.4 1.6 1.7e-06 27.7 1.6 2.0 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_16 PF13191.6 KXX77028.1 - 2.7e-06 27.9 0.0 0.023 15.1 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KXX77028.1 - 5.9e-06 26.7 0.1 0.017 15.6 0.1 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX77028.1 - 1.8e-05 25.1 0.2 0.0044 17.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXX77028.1 - 2.1e-05 24.4 0.3 0.16 11.6 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXX77028.1 - 0.00024 21.0 0.0 0.89 9.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase Fer4 PF00037.27 KXX77028.1 - 0.0003 20.5 1.9 0.0003 20.5 1.9 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_18 PF13238.6 KXX77028.1 - 0.00037 21.0 0.1 1.7 9.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain Fer4_10 PF13237.6 KXX77028.1 - 0.0004 20.4 5.7 0.0046 17.0 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.15 KXX77028.1 - 0.00048 20.1 0.2 0.039 13.9 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 KXX77028.1 - 0.0005 20.6 0.5 0.091 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXX77028.1 - 0.00052 19.7 0.4 0.51 10.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KXX77028.1 - 0.00069 19.6 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 KXX77028.1 - 0.0008 19.8 0.1 0.35 11.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KXX77028.1 - 0.0012 18.6 0.2 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KXX77028.1 - 0.0016 18.1 3.2 0.047 13.3 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_9 PF13187.6 KXX77028.1 - 0.0023 18.1 9.1 0.0041 17.3 9.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 KXX77028.1 - 0.0023 17.6 0.3 1.1 8.9 0.1 2.9 3 0 0 3 3 3 1 Thymidylate kinase AAA_28 PF13521.6 KXX77028.1 - 0.0024 18.1 0.5 0.27 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXX77028.1 - 0.0032 17.0 0.3 0.065 12.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_13 PF13166.6 KXX77028.1 - 0.0036 16.0 1.0 0.0057 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 KXX77028.1 - 0.0043 17.1 0.1 0.055 13.5 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXX77028.1 - 0.0044 17.2 0.1 0.66 10.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXX77028.1 - 0.0077 16.2 0.3 0.4 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_21 PF14697.6 KXX77028.1 - 0.0079 16.3 1.1 0.0079 16.3 1.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain NB-ARC PF00931.22 KXX77028.1 - 0.01 15.1 0.0 0.5 9.5 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_6 PF12837.7 KXX77028.1 - 0.016 15.2 2.1 0.016 15.2 2.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_30 PF13604.6 KXX77028.1 - 0.03 14.0 0.4 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_7 PF12838.7 KXX77028.1 - 0.054 14.1 1.4 0.054 14.1 1.4 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXX77028.1 - 0.073 14.0 5.1 0.095 13.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.23 KXX77028.1 - 0.075 13.1 0.4 15 5.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 KXX77028.1 - 0.1 12.3 0.0 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E CLP1_P PF16575.5 KXX77028.1 - 0.14 12.0 0.7 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_17 PF13534.6 KXX77028.1 - 0.24 12.0 0.2 0.24 12.0 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 KXX77028.1 - 0.25 11.2 3.4 2.3 8.1 0.2 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 KXX77028.1 - 0.53 10.0 3.0 0.54 10.0 0.1 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.6 KXX77028.1 - 0.54 10.7 6.4 0.49 10.9 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KXX77028.1 - 1.8 8.8 7.5 0.28 11.4 1.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain SLD3 PF08639.10 KXX77029.1 - 2.5e-186 620.6 6.7 2.5e-186 620.6 6.7 1.6 2 0 0 2 2 2 1 DNA replication regulator SLD3 HrpB7 PF09486.10 KXX77029.1 - 1 9.7 5.0 0.19 12.1 0.8 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Trs65 PF12735.7 KXX77030.1 - 2.8e-109 365.3 0.0 8.1e-107 357.3 0.0 2.1 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Homeodomain PF00046.29 KXX77031.1 - 1e-15 57.3 0.7 2.7e-15 56.0 0.7 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXX77031.1 - 3.3e-05 23.7 0.1 7.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Pkinase PF00069.25 KXX77032.1 - 7e-68 228.8 0.0 1.4e-67 227.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77032.1 - 3.2e-37 128.2 0.0 5.5e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX77032.1 - 0.00026 20.4 0.0 0.00081 18.8 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXX77032.1 - 0.002 17.0 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXX77032.1 - 0.051 13.5 0.1 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXX77032.1 - 0.092 11.7 0.4 0.21 10.5 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KXX77032.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Mer2 PF09074.10 KXX77032.1 - 0.33 10.8 3.1 0.33 10.7 0.3 2.4 2 0 0 2 2 2 0 Mer2 DUF3500 PF12006.8 KXX77033.1 - 4.8e-110 367.7 0.0 5.6e-110 367.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Med16 PF11635.8 KXX77034.1 - 2.3e-84 283.8 0.0 4.1e-84 283.0 0.0 1.3 1 1 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 KXX77034.1 - 0.1 12.9 0.0 8.5 6.8 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Calpain_inhib PF00748.19 KXX77034.1 - 0.2 12.1 0.1 0.58 10.7 0.1 1.7 1 0 0 1 1 1 0 Calpain inhibitor tRNA-synt_1g PF09334.11 KXX77035.1 - 2.7e-142 474.2 0.0 3.4e-142 473.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXX77035.1 - 0.00031 19.1 0.2 0.0013 17.1 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) Glyco_transf_34 PF05637.12 KXX77036.1 - 2.1e-66 224.1 0.3 2.6e-66 223.7 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KXX77036.1 - 0.054 13.5 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_hydro_16 PF00722.21 KXX77037.1 - 4.7e-06 26.2 0.1 4.2e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CdiI_4 PF18624.1 KXX77037.1 - 0.22 12.0 0.9 0.59 10.6 0.0 2.0 2 0 0 2 2 2 0 CDI immunity protein Peptidase_M22 PF00814.25 KXX77038.1 - 6e-47 160.6 0.0 2.7e-16 60.1 0.1 4.2 4 1 0 4 4 4 4 Glycoprotease family UPF0016 PF01169.19 KXX77039.1 - 0.18 12.2 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 ABM PF03992.16 KXX77040.1 - 6.5e-06 26.2 0.0 0.0081 16.3 0.0 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AIP3 PF03915.13 KXX77041.1 - 6.9e-05 22.1 8.4 0.00011 21.5 8.4 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Abhydrolase_2 PF02230.16 KXX77041.1 - 0.054 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HAUS-augmin3 PF14932.6 KXX77041.1 - 0.12 11.9 12.4 0.016 14.8 7.2 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 KXX77041.1 - 0.24 10.7 13.1 0.17 11.3 4.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KXX77041.1 - 1 9.4 7.9 2.7 8.0 2.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 KXX77041.1 - 1.3 9.2 7.3 0.19 11.8 1.2 2.7 2 2 0 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 KXX77041.1 - 4.4 7.4 13.2 9.7 6.2 6.7 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Abhydrolase_2 PF02230.16 KXX77042.1 - 2.1e-09 37.5 0.1 0.00033 20.5 0.0 2.0 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase Shal-type PF11601.8 KXX77042.1 - 0.072 12.6 0.4 0.14 11.7 0.4 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal Peptidase_S9 PF00326.21 KXX77042.1 - 0.084 12.3 0.2 0.13 11.7 0.2 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXX77042.1 - 0.086 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1752 PF08550.10 KXX77043.1 - 2.7e-10 39.9 5.3 2.7e-10 39.9 5.3 2.6 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1752) Spt5_N PF11942.8 KXX77043.1 - 0.037 15.0 5.6 4.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Voldacs PF03517.13 KXX77043.1 - 0.42 10.7 2.5 21 5.2 0.3 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling PBP1_TM PF14812.6 KXX77043.1 - 4.9 7.6 17.1 3.9 7.9 2.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPP4R2 PF09184.11 KXX77043.1 - 9.7 5.7 8.9 34 3.9 8.9 2.0 1 1 0 1 1 1 0 PPP4R2 Proteasome PF00227.26 KXX77044.1 - 1.9e-48 164.5 0.3 2.3e-48 164.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-CCHC PF00098.23 KXX77045.1 - 2.9e-38 128.3 90.6 6.8e-07 29.1 1.3 11.9 11 1 0 11 11 11 10 Zinc knuckle zf-CCHC_4 PF14392.6 KXX77045.1 - 1.8e-07 30.8 45.2 0.15 11.8 2.1 9.3 8 1 1 9 9 9 7 Zinc knuckle zf-CCHC_6 PF15288.6 KXX77045.1 - 7.5e-05 22.5 71.7 0.065 13.1 0.9 9.7 9 2 2 11 11 11 6 Zinc knuckle zf-CCHC_3 PF13917.6 KXX77045.1 - 0.017 15.0 1.9 0.017 15.0 1.9 8.9 4 3 5 9 9 9 0 Zinc knuckle zf-CCHC_2 PF13696.6 KXX77045.1 - 0.018 14.9 2.6 0.018 14.9 2.6 10.2 11 0 0 11 11 11 0 Zinc knuckle zf-C2H2_10 PF16588.5 KXX77045.1 - 0.025 14.3 0.2 0.025 14.3 0.2 7.9 8 0 0 8 8 8 0 C2H2 zinc-finger FA_desaturase PF00487.24 KXX77046.1 - 1.7e-28 100.2 20.1 2.6e-28 99.6 20.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KXX77046.1 - 3.9e-18 64.6 0.3 7.7e-18 63.7 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Vac7 PF12751.7 KXX77047.1 - 1.1e-153 512.3 3.6 1.1e-153 512.3 3.6 2.3 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Acetyltransf_2 PF00797.17 KXX77048.1 - 1.4e-32 113.4 0.0 3.9e-32 112.0 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KXX77048.1 - 0.083 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily TTKRSYEDQ PF10212.9 KXX77049.1 - 0.0053 15.8 7.1 0.0053 15.8 7.1 1.9 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein ERM PF00769.19 KXX77049.1 - 1.4 8.6 40.4 0.37 10.6 34.7 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Ribosomal_L7Ae PF01248.26 KXX77050.1 - 6.3e-23 80.3 0.0 7.1e-23 80.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HTH_IclR PF09339.10 KXX77050.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_L16 PF00252.18 KXX77051.1 - 4.3e-44 149.7 0.0 5.4e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Proteasome PF00227.26 KXX77053.1 - 1.9e-47 161.2 0.0 2.6e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXX77053.1 - 1.4e-13 50.2 0.1 1.4e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TMEM234 PF10639.9 KXX77055.1 - 6.4e-35 119.7 0.1 9.5e-35 119.1 0.1 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KXX77055.1 - 2.8e-05 24.3 5.7 0.0096 16.1 5.7 2.3 1 1 0 1 1 1 1 EamA-like transporter family DUF1211 PF06736.11 KXX77055.1 - 0.039 14.4 0.1 0.57 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1211) C2 PF00168.30 KXX77056.1 - 1.3e-15 57.5 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain RrnaAD PF00398.20 KXX77057.1 - 1.6e-55 188.0 0.0 2.2e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KXX77057.1 - 1e-05 26.2 0.0 2.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KXX77057.1 - 0.0003 20.6 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 KXX77057.1 - 0.00054 19.3 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXX77057.1 - 0.0036 17.9 0.0 0.0078 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXX77057.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXX77057.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KXX77057.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_RFF PF18321.1 KXX77058.1 - 0.045 14.2 1.0 0.11 12.9 1.0 1.7 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain SUIM_assoc PF16619.5 KXX77058.1 - 0.28 11.3 10.3 0.063 13.3 1.3 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UTP15_C PF09384.10 KXX77059.1 - 8.3e-52 174.8 0.0 1.2e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KXX77059.1 - 1.6e-16 60.4 5.9 0.00011 22.9 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX77059.1 - 0.00078 19.7 0.2 4.2 7.7 0.0 4.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain zf-MIZ PF02891.20 KXX77060.1 - 1e-09 38.0 9.0 1.3e-08 34.4 1.1 2.6 1 1 1 2 2 2 2 MIZ/SP-RING zinc finger PINIT PF14324.6 KXX77060.1 - 0.15 12.4 0.3 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 PINIT domain zf-Nse PF11789.8 KXX77060.1 - 3.8 7.4 6.0 0.99 9.3 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Arrestin_N PF00339.29 KXX77061.1 - 4.9e-14 52.6 0.0 1.7e-08 34.6 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF1664 PF07889.12 KXX77062.1 - 0.0011 19.0 24.4 0.2 11.7 4.2 4.5 3 1 1 4 4 4 3 Protein of unknown function (DUF1664) ILVD_EDD PF00920.21 KXX77062.1 - 0.0014 17.3 0.1 0.0024 16.5 0.1 1.4 1 0 0 1 1 1 1 Dehydratase family DUF3952 PF13130.6 KXX77062.1 - 0.043 14.0 0.6 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) V_ATPase_I PF01496.19 KXX77062.1 - 0.41 8.5 20.9 0.53 8.1 10.9 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 KXX77062.1 - 1.9 7.1 9.8 2.6 6.6 9.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bacillus_HBL PF05791.11 KXX77062.1 - 1.9 8.3 12.1 1.2 9.0 2.2 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) SIS PF01380.22 KXX77063.1 - 3.8e-14 52.7 0.4 3.9e-13 49.4 0.0 2.2 2 1 0 2 2 2 1 SIS domain SIS_2 PF13580.6 KXX77063.1 - 0.0047 16.9 0.1 0.13 12.3 0.2 2.4 1 1 1 2 2 2 1 SIS domain DUF2373 PF10180.9 KXX77064.1 - 3.5e-25 87.6 1.2 6.2e-25 86.8 0.4 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) MFS_1 PF07690.16 KXX77065.1 - 2.1e-34 119.0 52.4 2.1e-34 119.0 52.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX77065.1 - 8.4e-12 44.3 23.2 2.4e-11 42.8 23.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RTX PF02382.15 KXX77065.1 - 0.98 9.0 6.9 1.8 8.2 6.9 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein tRNA_synthFbeta PF17759.1 KXX77066.1 - 2.1e-45 154.8 0.0 3.1e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KXX77066.1 - 5.8e-28 96.9 0.2 1.6e-26 92.3 0.1 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KXX77066.1 - 4.3e-25 88.4 0.0 7.2e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KXX77066.1 - 8.6e-16 58.0 0.0 4.4e-13 49.3 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain PAP2 PF01569.21 KXX77067.1 - 5.4e-19 68.3 3.6 5.4e-19 68.3 3.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KXX77067.1 - 0.00011 22.0 4.6 0.00035 20.3 4.6 2.1 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KXX77067.1 - 0.14 12.7 2.0 0.3 11.7 1.0 2.2 1 1 0 1 1 1 0 PAP2 superfamily C-terminal JmjC PF02373.22 KXX77068.1 - 1.3e-37 128.7 0.8 3.2e-37 127.5 0.8 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KXX77068.1 - 9.5e-21 74.0 4.2 1.7e-20 73.2 4.2 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXX77068.1 - 6e-20 71.3 3.6 6e-20 71.3 3.6 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 KXX77068.1 - 4.1e-13 49.0 2.2 8.8e-13 48.0 2.2 1.6 1 0 0 1 1 1 1 jmjN domain ThiF PF00899.21 KXX77069.1 - 7.8e-74 248.1 0.0 1.1e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KXX77069.1 - 2.4e-22 79.3 1.6 3.7e-22 78.7 0.4 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KXX77069.1 - 3.2e-07 30.6 2.0 8.4e-06 25.9 0.8 2.6 1 1 1 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KXX77069.1 - 0.00013 22.3 0.0 0.00043 20.7 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXX77069.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KXX77069.1 - 0.045 14.3 0.2 0.48 11.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 KXX77070.1 - 6.1e-48 163.4 0.0 8.1e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX77070.1 - 3.9e-47 160.2 0.0 5e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX77070.1 - 8.4e-07 29.1 0.2 1.4e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX77070.1 - 1.6e-06 27.7 0.0 2.7e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXX77070.1 - 7.9e-06 26.2 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXX77070.1 - 0.0001 21.5 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX77070.1 - 0.0041 16.6 0.0 0.0081 15.6 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXX77070.1 - 0.0088 15.2 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 KXX77070.1 - 0.012 16.2 0.0 0.025 15.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXX77070.1 - 0.019 14.3 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXX77070.1 - 0.029 14.3 0.1 0.067 13.1 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 KXX77070.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CinA PF02464.17 KXX77071.1 - 1.7e-40 138.1 0.0 2.2e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Competence-damaged protein MeaB PF03308.16 KXX77071.1 - 0.29 10.1 3.0 0.46 9.4 3.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HET PF06985.11 KXX77072.1 - 2.3e-22 79.9 0.0 4.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4440 PF14534.6 KXX77073.1 - 0.00034 21.0 0.1 0.00048 20.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KXX77073.1 - 0.05 14.3 0.2 0.077 13.6 0.2 1.4 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.16 KXX77074.1 - 5.4e-38 130.8 25.1 5.4e-38 130.8 25.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX77074.1 - 5.1e-17 61.9 0.5 5.1e-17 61.9 0.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Adeno_PIX PF03955.14 KXX77074.1 - 0.68 10.1 5.7 3.4 7.9 0.0 3.2 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) UPF0731 PF14982.6 KXX77075.1 - 7.7 6.8 7.5 6.4 7.0 0.2 2.5 2 0 0 2 2 2 0 UPF0731 family HET PF06985.11 KXX77076.1 - 6.8e-25 88.1 0.0 1.2e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.21 KXX77078.1 - 1.1e-139 466.1 37.2 1.3e-139 465.9 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX77078.1 - 2.8e-36 125.3 40.5 3.8e-36 124.8 40.5 1.2 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 KXX77079.1 - 1.1e-16 60.9 0.0 1.2e-14 54.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX77079.1 - 6e-06 26.0 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX77079.1 - 7e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KXX77080.1 - 0.0041 16.0 1.6 0.009 14.9 1.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Exo84_C PF16528.5 KXX77080.1 - 0.027 14.3 0.2 0.81 9.5 0.0 2.4 2 0 0 2 2 2 0 Exocyst component 84 C-terminal Q_salvage PF10343.9 KXX77081.1 - 2e-130 434.5 0.0 2.4e-130 434.2 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 KXX77081.1 - 0.2 11.8 0.9 0.36 10.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) DNA_pol_delta_4 PF04081.13 KXX77082.1 - 2.6e-40 137.8 6.0 1.5e-39 135.3 6.0 1.9 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF966 PF06136.13 KXX77082.1 - 0.31 10.7 6.5 0.39 10.4 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ANAPC4_WD40 PF12894.7 KXX77083.1 - 1.8e-14 53.8 0.4 0.00062 20.0 0.3 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX77083.1 - 2e-14 53.7 8.0 1.5e-05 25.6 0.1 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat Ribosomal_L32p PF01783.23 KXX77083.1 - 6.3e-13 48.8 8.3 6.3e-13 48.8 8.3 1.8 2 0 0 2 2 2 1 Ribosomal L32p protein family Hira PF07569.11 KXX77083.1 - 0.00035 20.4 0.3 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 TUP1-like enhancer of split Nup160 PF11715.8 KXX77083.1 - 0.003 16.3 0.2 0.077 11.6 0.2 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 zinc-ribbons_6 PF07191.12 KXX77083.1 - 0.015 15.3 3.0 0.04 13.9 3.0 1.7 1 0 0 1 1 1 0 zinc-ribbons eIF2A PF08662.11 KXX77083.1 - 0.017 15.0 0.1 1.1 9.0 0.0 2.9 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KXX77083.1 - 0.02 15.4 3.5 0.68 10.5 0.1 2.8 2 0 0 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.16 KXX77083.1 - 0.029 12.9 0.2 0.31 9.5 0.1 1.9 1 1 0 2 2 2 0 Cytochrome D1 heme domain PolC_DP2 PF03833.13 KXX77083.1 - 0.029 12.2 0.6 0.039 11.8 0.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Nbas_N PF15492.6 KXX77083.1 - 0.052 12.9 0.2 5.2 6.3 0.0 3.0 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KXX77083.1 - 0.17 10.8 2.7 0.41 9.5 0.1 2.5 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Septin PF00735.18 KXX77084.1 - 1.7e-113 378.6 1.0 2.1e-113 378.3 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXX77084.1 - 1e-07 32.0 0.1 1.9e-07 31.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KXX77084.1 - 1.6e-06 27.6 0.0 3.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KXX77084.1 - 5.2e-06 26.5 0.2 0.00016 21.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KXX77084.1 - 1.8e-05 24.4 0.5 0.009 15.6 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXX77084.1 - 0.00086 19.4 0.4 1.3 9.1 0.2 2.6 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 KXX77084.1 - 0.0035 17.6 0.1 0.0078 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXX77084.1 - 0.0044 16.6 0.0 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KXX77084.1 - 0.0049 17.3 0.0 0.023 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KXX77084.1 - 0.0055 15.9 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Microtub_bd PF16796.5 KXX77084.1 - 0.0082 16.1 0.1 0.47 10.4 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Gtr1_RagA PF04670.12 KXX77084.1 - 0.011 15.1 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KXX77084.1 - 0.014 15.9 0.7 0.024 15.2 0.6 1.7 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KXX77084.1 - 0.04 13.1 1.1 0.091 11.9 1.1 1.7 1 1 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KXX77084.1 - 0.046 13.1 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 KXX77084.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXX77084.1 - 0.065 12.8 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Ras family DUF1104 PF06518.11 KXX77084.1 - 0.084 13.3 0.5 1.2 9.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) AAA_23 PF13476.6 KXX77084.1 - 0.1 13.1 1.0 0.18 12.3 0.7 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXX77084.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain F-box-like PF12937.7 KXX77085.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like RabGAP-TBC PF00566.18 KXX77086.1 - 5.2e-46 157.0 0.0 8.2e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-1_beta_acid PF10587.9 KXX77086.1 - 1.7 9.2 9.2 6.3 7.3 9.2 2.1 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Popeye PF04831.13 KXX77088.1 - 2.1 8.5 9.2 0.35 11.1 4.3 2.2 2 0 0 2 2 2 0 Popeye protein conserved region Ribosomal_S26e PF01283.19 KXX77089.1 - 3.4e-53 178.6 9.3 4e-53 178.4 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.11 KXX77089.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) zf_CopZ PF18423.1 KXX77089.1 - 0.019 14.9 0.4 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 KXX77089.1 - 0.18 11.6 2.0 0.22 11.4 2.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) MF_alpha_N PF05436.11 KXX77090.1 - 0.19 11.6 0.4 0.32 10.9 0.4 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus PepSY_2 PF13670.6 KXX77090.1 - 0.25 11.4 2.1 0.26 11.3 0.5 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Polysacc_deac_1 PF01522.21 KXX77091.1 - 1.7e-13 50.6 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXX77091.1 - 1.2e-06 28.3 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Luciferase_cat PF10285.9 KXX77091.1 - 0.16 11.3 0.2 0.22 10.9 0.2 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain ubiquitin PF00240.23 KXX77092.1 - 5e-34 115.9 1.0 7.9e-34 115.2 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KXX77092.1 - 9.6e-27 92.9 1.8 9.6e-27 92.9 1.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KXX77092.1 - 2.4e-16 59.3 0.7 4.9e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXX77092.1 - 2.4e-05 24.7 0.5 0.00013 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXX77092.1 - 0.00071 19.6 0.7 0.0016 18.5 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXX77092.1 - 0.0044 17.3 0.9 0.0076 16.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXX77092.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KXX77092.1 - 0.01 16.4 0.7 0.014 15.9 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXX77092.1 - 0.019 15.0 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Glyco_hydro_18 PF00704.28 KXX77093.1 - 2.4e-83 280.5 0.0 2.8e-83 280.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 KXX77093.1 - 0.037 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Ank_2 PF12796.7 KXX77094.1 - 2.1e-08 34.7 0.0 9.8e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX77094.1 - 1.7e-06 27.9 0.0 2.4e-05 24.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXX77094.1 - 3.1e-06 27.6 0.0 9.7e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX77094.1 - 3.7e-06 27.1 0.0 4.3e-05 23.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX77094.1 - 1.7e-05 25.0 0.1 7e-05 23.1 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeat Helo_like_N PF17111.5 KXX77094.1 - 0.00037 19.9 0.1 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXX77094.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1834 PF08873.11 KXX77094.1 - 0.062 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) TPR_12 PF13424.6 KXX77095.1 - 2e-08 34.4 3.2 0.0002 21.6 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX77095.1 - 2.8e-07 30.1 5.4 0.062 13.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Helo_like_N PF17111.5 KXX77095.1 - 1.9e-06 27.4 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TPR_2 PF07719.17 KXX77095.1 - 2.6e-05 24.0 7.8 0.29 11.4 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXX77095.1 - 0.00015 21.5 2.2 0.29 11.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX77095.1 - 0.00059 20.3 0.6 0.31 11.6 0.4 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXX77095.1 - 0.0016 18.2 5.1 0.88 9.5 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXX77095.1 - 0.0025 17.9 1.2 0.36 11.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat lci PF12197.8 KXX77095.1 - 0.11 12.4 0.5 6.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein ANAPC3 PF12895.7 KXX77095.1 - 1.4 9.2 3.9 36 4.7 0.1 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KXX77095.1 - 4.1 8.3 6.5 3.5 8.5 0.4 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4188 PF13826.6 KXX77096.1 - 3.5e-28 98.3 0.1 5.1e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF1330 PF07045.11 KXX77096.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Dabb PF07876.12 KXX77096.1 - 0.1 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain p450 PF00067.22 KXX77097.1 - 5.3e-52 177.1 0.0 8.6e-52 176.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 CFEM PF05730.11 KXX77100.1 - 3.3e-06 27.1 7.5 5.8e-06 26.3 7.5 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.16 KXX77101.1 - 3.2e-46 157.9 52.9 8.5e-46 156.5 52.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX77101.1 - 7.8e-14 51.0 23.1 2.1e-13 49.6 23.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX77101.1 - 8.2e-10 38.1 9.8 8.2e-10 38.1 9.8 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KXX77101.1 - 9.6e-05 20.9 4.0 9.6e-05 20.9 4.0 3.0 2 2 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF2844 PF11005.8 KXX77102.1 - 0.019 15.0 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) Insulin_TMD PF17870.1 KXX77103.1 - 0.0017 18.4 0.9 0.0026 17.8 0.9 1.2 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 KXX77103.1 - 0.0043 17.9 0.0 0.0067 17.3 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain MASE1 PF05231.14 KXX77103.1 - 0.027 13.6 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 MASE1 Mid2 PF04478.12 KXX77103.1 - 0.045 13.6 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor RIFIN PF02009.16 KXX77103.1 - 0.065 13.1 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Rifin LapA_dom PF06305.11 KXX77103.1 - 0.071 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3827 PF12877.7 KXX77103.1 - 0.12 10.7 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4381 PF14316.6 KXX77103.1 - 0.16 12.2 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3844 PF12955.7 KXX77103.1 - 0.17 12.0 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) Mrr_N PF14338.6 KXX77103.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Mrr N-terminal domain DUF2207 PF09972.9 KXX77103.1 - 0.2 10.4 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 KXX77103.1 - 0.24 11.3 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Rhabdo_glycop PF00974.18 KXX77103.1 - 0.26 9.7 0.0 0.33 9.3 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein FeoB_associated PF12669.7 KXX77103.1 - 0.27 11.7 2.5 1.1 9.8 2.5 2.0 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Collectrin PF16959.5 KXX77103.1 - 4.4 7.1 8.7 16 5.2 6.0 2.0 1 1 1 2 2 2 0 Renal amino acid transporter DUF829 PF05705.14 KXX77104.1 - 2.9e-23 83.0 0.2 9.8e-20 71.5 0.1 2.7 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Ribosomal_S2 PF00318.20 KXX77105.1 - 1.3e-62 210.8 0.0 4.8e-61 205.7 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.28 KXX77106.1 - 4.8e-35 119.8 9.3 1e-08 35.4 0.0 6.1 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 KXX77106.1 - 2.1e-09 37.2 0.0 8.5e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 PB1 domain Cpn60_TCP1 PF00118.24 KXX77107.1 - 4.4e-156 520.3 5.2 5e-156 520.2 5.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 KXX77107.1 - 0.012 16.0 0.1 2.9 8.3 0.0 3.0 2 0 0 2 2 2 0 Replication factor C C-terminal domain GNAT_acetyltran PF12746.7 KXX77107.1 - 0.063 12.8 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 GNAT acetyltransferase PNTB_4TM PF12769.7 KXX77107.1 - 0.11 13.0 0.0 0.46 11.0 0.0 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch zf-H2C2 PF09337.10 KXX77108.1 - 2.1e-16 59.8 1.2 4.1e-16 58.9 1.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KXX77108.1 - 6.4e-12 45.4 0.1 6.4e-12 45.4 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KXX77108.1 - 4.5e-05 23.7 0.0 8.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXX77108.1 - 0.0028 17.8 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXX77108.1 - 0.057 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KXX77109.1 - 1.6e-26 92.7 0.0 2.3e-07 31.3 0.0 6.4 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77109.1 - 8e-22 77.3 3.7 8.9e-06 26.2 0.0 7.1 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77109.1 - 5.1e-20 69.4 5.9 0.016 15.6 0.0 9.5 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 KXX77109.1 - 6.9e-18 64.2 13.6 0.0072 16.7 0.3 8.7 10 1 1 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 KXX77109.1 - 1.1e-14 54.3 8.2 0.02 15.2 0.2 8.2 8 2 2 10 10 10 5 Ankyrin repeats (many copies) F-box-like PF12937.7 KXX77109.1 - 1.3e-07 31.4 0.1 3.2e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX77109.1 - 0.0023 17.8 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXX77109.1 - 0.034 14.0 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 F-box Ank_2 PF12796.7 KXX77110.1 - 1.9e-22 79.6 9.6 4e-06 27.3 0.1 8.2 8 1 1 9 9 9 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX77110.1 - 3.3e-19 66.9 5.2 0.0013 19.0 0.1 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 KXX77110.1 - 7e-18 64.8 6.3 0.00033 21.1 0.1 8.8 8 1 2 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 KXX77110.1 - 2.8e-16 59.2 16.0 0.00023 21.4 1.0 8.4 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KXX77110.1 - 7.3e-15 54.9 11.9 0.00079 19.7 0.1 7.4 8 1 2 10 10 10 5 Ankyrin repeats (many copies) F-box-like PF12937.7 KXX77110.1 - 5.1e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like AAL_decarboxy PF03306.13 KXX77111.1 - 8.7e-79 263.9 0.2 9.9e-79 263.7 0.2 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Torus PF16131.5 KXX77112.1 - 1.1e-07 32.5 0.1 0.0025 18.5 0.0 2.7 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 KXX77112.1 - 5.8e-05 22.9 0.8 5.8e-05 22.9 0.8 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXX77112.1 - 0.0021 18.1 14.8 0.069 13.2 1.5 3.1 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 KXX77112.1 - 1.5 9.4 6.2 3.6 8.2 1.0 3.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger FAA_hydrolase PF01557.18 KXX77113.1 - 2.6e-29 102.5 0.0 3.7e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tnp_P_element_C PF12596.8 KXX77113.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 87kDa Transposase Glyco_hydro_125 PF06824.11 KXX77114.1 - 5.9e-179 595.3 0.0 6.8e-179 595.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CTD_bind PF04818.13 KXX77114.1 - 0.21 12.5 0.0 3.7 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II-binding domain. CDC27 PF09507.10 KXX77115.1 - 1.4e-68 232.3 35.3 6.8e-68 230.0 35.3 2.3 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 K_channel_TID PF07941.11 KXX77115.1 - 0.062 13.8 2.2 0.16 12.5 2.2 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF4823 PF16105.5 KXX77115.1 - 0.088 12.7 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) CDC45 PF02724.14 KXX77115.1 - 1.7 6.8 12.3 2.2 6.5 12.3 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KXX77115.1 - 1.9 7.8 10.6 3.3 7.0 10.6 1.4 1 0 0 1 1 1 0 NOA36 protein Fungal_trans PF04082.18 KXX77116.1 - 1.6e-37 129.0 0.0 3.1e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dna2 PF08696.11 KXX77116.1 - 0.0029 17.4 0.4 0.0052 16.6 0.4 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 PigN PF04987.14 KXX77117.1 - 5e-166 553.1 28.0 6.7e-166 552.7 28.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KXX77117.1 - 4.9e-11 42.8 2.0 3.9e-09 36.5 1.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXX77117.1 - 5e-07 29.4 0.1 8.4e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase RNase_PH PF01138.21 KXX77118.1 - 1.9e-26 93.1 0.0 3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Sec7 PF01369.20 KXX77119.1 - 2.1e-63 213.3 0.0 3.1e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXX77119.1 - 9.9e-17 61.3 0.0 1.8e-15 57.2 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXX77119.1 - 0.014 15.1 0.0 0.056 13.1 0.0 2.0 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Tti2 PF10521.9 KXX77120.1 - 3e-91 305.9 0.0 4.3e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 KXX77120.1 - 3.4e-24 85.7 0.3 8.4e-24 84.4 0.3 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KXX77120.1 - 1.2e-07 31.4 0.0 3.6e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A RNA_pol_Rpb8 PF03870.15 KXX77121.1 - 4.8e-44 149.9 0.0 5.5e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KXX77121.1 - 0.00066 19.7 0.1 0.082 13.0 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 KXX77122.1 - 1.1e-94 317.7 0.0 1.6e-94 317.1 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein Prok-JAB PF14464.6 KXX77122.1 - 0.16 11.7 0.5 0.3 10.9 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain tRNA_int_endo PF01974.17 KXX77123.1 - 1.7e-13 50.4 0.0 3.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF2797 PF10977.8 KXX77123.1 - 0.25 11.2 2.5 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) zf-C3HC4_3 PF13920.6 KXX77124.1 - 3.2e-07 30.1 15.9 5.4e-07 29.4 15.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GGA_N-GAT PF18308.1 KXX77124.1 - 0.31 10.7 1.3 3 7.5 0.2 2.4 2 0 0 2 2 2 0 GGA N-GAT domain DUF2568 PF10823.8 KXX77124.1 - 1.5 9.1 10.3 0.39 11.0 2.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) Glyco_hydro_47 PF01532.20 KXX77125.1 - 1.2e-175 584.8 0.0 1.4e-175 584.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CEND1 PF15677.5 KXX77126.1 - 0.00083 19.9 0.5 0.0017 18.9 0.5 1.5 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 Alpha_GJ PF03229.13 KXX77126.1 - 0.01 16.4 6.3 0.026 15.1 6.3 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF3446 PF11928.8 KXX77126.1 - 0.98 9.8 12.5 0.57 10.5 8.2 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain RRM_1 PF00076.22 KXX77127.1 - 1.3e-26 92.2 0.6 1.5e-12 47.1 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXX77127.1 - 0.00028 20.5 0.0 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXX77127.1 - 0.0038 17.1 0.0 0.33 10.9 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF1866 PF08952.11 KXX77127.1 - 0.044 13.6 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF4523 PF15023.6 KXX77127.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) ATP-synt_D PF01813.17 KXX77128.1 - 1.8e-47 161.8 2.6 2e-46 158.3 2.6 2.1 1 1 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 KXX77128.1 - 0.0052 16.9 0.7 0.011 15.8 0.7 1.7 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 DUF3847 PF12958.7 KXX77128.1 - 0.0097 16.0 0.2 0.025 14.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3847) DUF1151 PF06625.11 KXX77128.1 - 0.064 13.2 1.8 0.11 12.4 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DUF775 PF05603.12 KXX77129.1 - 4.3e-40 137.4 0.0 1.7e-39 135.4 0.0 1.7 1 1 1 2 2 2 2 Protein of unknown function (DUF775) DUF4743 PF15916.5 KXX77130.1 - 8.1e-11 41.9 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KXX77130.1 - 5.2e-10 39.5 0.0 9.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GDA1_CD39 PF01150.17 KXX77131.1 - 9.2e-104 347.4 0.0 1.3e-103 347.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Anp1 PF03452.14 KXX77132.1 - 2.1e-113 378.2 0.1 5e-113 376.9 0.0 1.6 2 0 0 2 2 2 1 Anp1 HSP70 PF00012.20 KXX77132.1 - 0.87 7.7 5.3 1.3 7.1 5.3 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4407 PF14362.6 KXX77132.1 - 1.1 8.5 6.2 2.7 7.3 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syja_N PF02383.18 KXX77133.1 - 8.9e-75 251.9 0.1 2.6e-74 250.4 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain FSH1 PF03959.13 KXX77136.1 - 5.6e-32 111.1 0.0 1.7e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BRO1 PF03097.18 KXX77137.1 - 6.1e-133 443.4 3.0 6.1e-133 443.4 3.0 2.5 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXX77137.1 - 8.5e-79 264.9 20.5 1.8e-78 263.9 20.5 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Phage_tail_APC PF16778.5 KXX77137.1 - 0.0053 16.6 0.6 0.76 9.7 0.3 3.1 2 0 0 2 2 2 1 Phage tail assembly chaperone protein DUF3232 PF11554.8 KXX77137.1 - 0.4 11.1 3.8 2.9 8.3 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) COG2 PF06148.11 KXX77137.1 - 0.99 9.5 9.5 0.088 12.9 1.1 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KXX77137.1 - 1 9.8 3.2 1.1 9.6 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1539 PF07560.11 KXX77137.1 - 1.6 8.8 8.2 1.9 8.6 0.1 3.6 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1539) DUF3435 PF11917.8 KXX77138.1 - 8.8e-116 387.3 0.0 1.1e-115 386.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) kleA_kleC PF17383.2 KXX77138.1 - 3.8 7.9 5.5 1.3 9.4 1.8 2.1 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A KASH_CCD PF14662.6 KXX77138.1 - 3.8 7.3 8.5 0.2 11.4 1.9 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2951 PF11166.8 KXX77138.1 - 5.9 7.2 5.7 1.8 8.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2_4 PF13894.6 KXX77140.1 - 4.9e-14 51.8 20.6 0.0057 17.4 0.1 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXX77140.1 - 5.2e-08 33.2 21.6 0.18 12.1 1.8 5.2 2 2 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KXX77140.1 - 5.3e-07 29.8 26.5 0.006 17.0 1.5 6.3 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXX77140.1 - 2.6e-06 27.5 17.6 0.00015 21.9 1.1 5.1 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KXX77140.1 - 2.9e-06 27.4 23.8 0.0083 16.5 0.2 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.7 KXX77140.1 - 0.00024 21.4 26.6 0.00081 19.7 0.7 5.5 5 1 0 5 5 5 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KXX77140.1 - 0.0072 16.4 22.2 0.18 11.9 1.6 5.4 4 1 0 4 4 4 2 Zinc ribbon domain zf-Di19 PF05605.12 KXX77140.1 - 0.041 14.2 0.1 0.041 14.2 0.1 4.7 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KXX77140.1 - 0.076 13.0 21.7 4.5 7.4 1.4 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 KXX77140.1 - 0.4 10.8 8.7 4.3 7.5 4.5 2.8 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 KXX77140.1 - 0.51 10.3 16.4 0.57 10.1 1.6 4.1 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.5 KXX77140.1 - 0.97 9.3 5.2 6.6 6.7 0.0 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-DBF PF07535.12 KXX77140.1 - 1.8 8.8 12.3 0.21 11.7 1.5 3.5 3 0 0 3 3 3 0 DBF zinc finger AKAP95 PF04988.12 KXX77140.1 - 2.4 8.4 10.3 2.1 8.6 0.3 3.4 3 2 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) Zn_ribbon_SprT PF17283.2 KXX77140.1 - 5.9 6.9 17.2 0.088 12.7 3.2 3.8 4 1 0 4 4 4 0 SprT-like zinc ribbon domain HypA PF01155.19 KXX77140.1 - 6.4 6.8 16.6 3.6 7.7 4.0 3.5 2 2 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SET PF00856.28 KXX77141.1 - 2.1e-11 44.5 0.0 1.2e-10 42.0 0.0 2.1 1 1 0 1 1 1 1 SET domain DUF4408 PF14364.6 KXX77142.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) DUF3295 PF11702.8 KXX77143.1 - 7.7e-86 289.4 4.7 9.3e-86 289.1 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) PAZ PF02170.22 KXX77147.1 - 5.3e-05 23.1 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain HET PF06985.11 KXX77150.1 - 9.2e-17 61.7 0.0 1.8e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BCS1_N PF08740.11 KXX77151.1 - 1.8e-33 116.1 2.0 2.9e-33 115.5 0.5 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KXX77151.1 - 1e-18 68.0 0.0 2e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX77151.1 - 0.00018 21.9 0.0 0.0004 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KXX77151.1 - 0.0027 16.9 0.0 0.007 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXX77151.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXX77151.1 - 0.036 14.1 0.0 0.082 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KXX77151.1 - 0.042 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KXX77151.1 - 0.063 13.8 0.0 0.2 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXX77151.1 - 0.064 13.8 0.1 0.83 10.2 0.0 2.6 3 1 0 3 3 3 0 ABC transporter AAA_25 PF13481.6 KXX77151.1 - 0.067 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX77151.1 - 0.081 12.6 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 KXX77151.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_22 PF13401.6 KXX77151.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pkinase_fungal PF17667.1 KXX77153.1 - 2.4e-136 454.8 0.0 3e-136 454.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KXX77153.1 - 0.00021 20.8 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXX77153.1 - 0.06 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family MRP-S23 PF10484.9 KXX77153.1 - 0.11 12.8 0.0 10 6.4 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 Pkinase_Tyr PF07714.17 KXX77153.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3435 PF11917.8 KXX77154.1 - 4.8e-120 401.3 0.0 6.1e-120 401.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_int_SAM_5 PF13102.6 KXX77154.1 - 6.8e-05 23.1 0.6 0.00084 19.6 0.0 2.7 2 1 1 3 3 3 1 Phage integrase SAM-like domain DUF3584 PF12128.8 KXX77154.1 - 0.0094 13.5 3.3 0.015 12.9 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 KXX77154.1 - 0.018 15.2 0.8 0.018 15.2 0.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TACC_C PF05010.14 KXX77154.1 - 0.025 14.4 1.1 0.025 14.4 1.1 1.8 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RapA_C PF12137.8 KXX77154.1 - 0.044 12.8 0.5 0.074 12.1 0.5 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal UPF0242 PF06785.11 KXX77154.1 - 0.23 11.5 4.9 0.16 12.1 1.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KXX77154.1 - 5.4 5.8 7.9 5.3 5.8 1.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-C2H2 PF00096.26 KXX77154.1 - 5.4 7.7 10.5 4 8.1 2.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type SOCS PF12610.8 KXX77154.1 - 9.4 6.7 9.3 1.2 9.6 3.5 2.5 3 0 0 3 3 3 0 Suppressor of cytokine signalling Acyltransferase PF01553.21 KXX77156.1 - 4.4e-30 104.0 0.0 6.8e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2347 PF09804.9 KXX77157.1 - 1e-101 340.2 0.0 1.3e-101 339.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KXX77157.1 - 2e-65 220.8 0.0 3.5e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 KXX77157.1 - 0.00048 20.1 0.0 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KXX77157.1 - 0.016 13.9 0.0 0.094 11.4 0.0 1.9 2 0 0 2 2 2 0 Transport protein Avl9 RCC1 PF00415.18 KXX77159.1 - 6.5e-58 193.2 0.2 6.2e-08 33.1 0.0 7.8 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXX77159.1 - 2e-38 129.4 12.9 1.1e-07 31.4 0.1 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 KXX77159.1 - 1.3e-09 38.5 0.9 0.0018 19.0 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ORC6 PF05460.13 KXX77159.1 - 0.013 14.8 9.6 0.02 14.2 9.6 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Methyltransf_16 PF10294.9 KXX77161.1 - 5.9e-28 97.8 0.0 1.1e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXX77161.1 - 6.2e-05 22.9 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77161.1 - 0.0025 18.5 0.0 0.0057 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX77161.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KXX77161.1 - 0.083 13.6 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KXX77161.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 KXX77161.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_1 PF00515.28 KXX77162.1 - 3.7e-44 146.8 5.3 5e-07 29.3 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXX77162.1 - 6.5e-37 122.7 9.6 5.7e-07 29.2 0.0 8.2 7 1 2 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.31 KXX77162.1 - 8e-27 93.2 2.2 2.3e-26 91.7 1.7 2.2 2 0 0 2 2 1 1 DnaJ domain TPR_11 PF13414.6 KXX77162.1 - 8.4e-26 89.4 10.2 7.6e-06 25.5 0.1 7.6 4 3 4 8 8 8 5 TPR repeat TPR_19 PF14559.6 KXX77162.1 - 7.5e-25 87.2 5.9 2.7e-08 34.2 0.0 5.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXX77162.1 - 3.8e-22 76.6 1.6 0.009 16.2 0.1 7.0 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXX77162.1 - 1.1e-20 74.0 3.4 9.2e-05 23.0 0.1 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX77162.1 - 3e-18 64.4 0.2 0.031 14.3 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXX77162.1 - 2.6e-17 62.9 6.9 0.00048 20.3 0.1 5.9 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXX77162.1 - 2.2e-16 59.8 4.5 0.0054 16.8 0.1 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXX77162.1 - 2.3e-16 59.1 13.2 0.00013 22.5 0.1 8.0 5 2 4 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXX77162.1 - 1.1e-15 56.8 13.4 0.0059 16.9 0.0 7.4 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 KXX77162.1 - 9.1e-14 51.1 10.9 0.13 12.9 0.0 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX77162.1 - 9.9e-13 48.1 2.8 5.1e-05 23.4 0.1 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXX77162.1 - 1.1e-06 28.3 7.7 0.097 12.6 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXX77162.1 - 2.2e-06 27.1 4.4 0.02 14.1 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXX77162.1 - 3e-05 24.0 2.0 7 6.8 0.0 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KXX77162.1 - 5.7e-05 23.6 7.0 0.18 12.2 0.0 4.6 3 1 2 5 5 5 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KXX77162.1 - 0.00013 21.1 1.1 0.035 13.0 0.3 3.1 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KXX77162.1 - 0.0009 19.6 3.1 0.43 11.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 KXX77162.1 - 0.0045 17.0 1.4 7 6.8 0.0 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.9 KXX77162.1 - 0.006 16.7 0.3 12 6.1 0.0 3.6 3 2 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_MalT PF17874.1 KXX77162.1 - 0.0074 15.7 0.3 1.1 8.6 0.0 3.0 2 2 1 3 3 3 2 MalT-like TPR region TPR_21 PF09976.9 KXX77162.1 - 0.0087 15.8 4.8 6.9 6.3 0.0 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 KXX77162.1 - 0.015 15.3 0.3 4.9 7.2 0.0 3.2 2 1 3 5 5 5 0 Putative TPR-like repeat RRM_3 PF08777.11 KXX77162.1 - 0.015 15.3 0.1 0.063 13.3 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif TPR_20 PF14561.6 KXX77162.1 - 0.033 14.5 5.2 1.9 8.9 0.1 4.4 3 3 2 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 KXX77162.1 - 0.08 11.9 0.1 0.42 9.6 0.0 2.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Glyoxalase PF00903.25 KXX77162.1 - 0.14 12.4 0.0 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3856 PF12968.7 KXX77162.1 - 0.2 11.7 0.8 27 4.8 0.0 3.7 4 2 0 4 4 3 0 Domain of Unknown Function (DUF3856) DnaJ PF00226.31 KXX77163.1 - 2.4e-16 59.6 1.6 6e-16 58.3 1.6 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KXX77163.1 - 1.5e-07 30.8 0.0 4e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Sec63 Brl domain RRN3 PF05327.11 KXX77163.1 - 7.9 4.9 6.2 12 4.3 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Afi1 PF07792.12 KXX77164.1 - 2.4e-47 160.7 0.1 4.5e-47 159.8 0.1 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KXX77164.1 - 4.3e-37 126.6 0.0 7.5e-37 125.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KXX77164.1 - 1.2e-07 30.8 0.3 0.023 13.4 0.0 3.4 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 KXX77164.1 - 0.057 13.0 0.0 0.33 10.5 0.0 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) EF-hand_6 PF13405.6 KXX77165.1 - 3.8e-12 45.1 1.7 2.6e-05 23.8 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KXX77165.1 - 6.4e-10 37.9 1.4 0.00098 18.5 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXX77165.1 - 1.1e-06 28.9 0.3 6.5e-06 26.5 0.3 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXX77165.1 - 1.2e-05 24.5 3.9 0.017 14.6 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KXX77165.1 - 1.5e-05 24.8 0.0 0.098 12.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KXX77165.1 - 0.00047 20.4 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Esterase PF00756.20 KXX77167.1 - 9.1e-48 163.1 0.0 1.1e-47 162.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KXX77167.1 - 0.00014 21.4 0.1 0.00041 19.9 0.1 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXX77167.1 - 0.0069 15.9 0.1 0.011 15.3 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXX77167.1 - 0.011 15.0 0.1 0.031 13.5 0.1 1.6 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXX77167.1 - 0.028 15.0 0.1 0.036 14.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 KXX77167.1 - 0.12 11.9 2.2 0.56 9.7 2.2 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family GARS_A PF01071.19 KXX77168.1 - 1.5e-82 276.1 0.0 2.2e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KXX77168.1 - 4e-34 117.3 0.0 1.3e-33 115.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KXX77168.1 - 1.3e-33 116.4 0.0 3.5e-33 114.9 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KXX77168.1 - 1.5e-26 92.5 1.6 3e-26 91.5 0.2 2.3 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KXX77168.1 - 2.4e-13 50.5 2.2 1.1e-12 48.4 2.5 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 KXX77168.1 - 3.2e-05 23.6 0.1 5.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KXX77168.1 - 0.00036 20.1 0.2 0.00069 19.2 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KXX77168.1 - 0.0013 18.4 0.0 0.0042 16.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXX77168.1 - 0.0022 18.1 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KXX77168.1 - 0.033 13.8 0.3 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 KXX77168.1 - 0.2 10.9 0.1 0.44 9.7 0.1 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Ank_2 PF12796.7 KXX77170.1 - 8.5e-75 247.4 2.1 1.6e-16 60.6 0.0 8.7 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77170.1 - 1.2e-59 197.9 5.5 5.8e-08 33.1 0.0 11.9 4 1 8 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KXX77170.1 - 2.1e-55 182.9 0.6 1.9e-05 24.9 0.1 13.7 14 0 0 14 14 14 10 Ankyrin repeat Ank_3 PF13606.6 KXX77170.1 - 8.4e-50 160.9 0.0 0.00016 21.8 0.0 15.4 15 1 1 16 16 16 12 Ankyrin repeat Ank_5 PF13857.6 KXX77170.1 - 8.3e-46 153.5 8.6 1.4e-07 31.6 0.1 11.4 5 3 6 11 11 11 9 Ankyrin repeats (many copies) Pro_isomerase PF00160.21 KXX77171.1 - 1.5e-45 155.3 0.0 2.5e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KXX77171.1 - 7.8e-05 22.8 0.0 0.00037 20.6 0.0 2.1 2 0 0 2 2 2 1 U-box domain Rtf2 PF04641.12 KXX77171.1 - 0.0025 17.3 0.0 0.0058 16.0 0.0 1.7 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KXX77171.1 - 0.0078 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein MFS_1 PF07690.16 KXX77172.1 - 8.5e-39 133.5 61.9 7.7e-38 130.3 59.4 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXX77172.1 - 3 6.0 18.9 4.5 5.4 0.1 3.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family NACHT PF05729.12 KXX77173.1 - 1.2e-05 25.3 0.0 6.2e-05 23.0 0.0 2.2 2 1 0 2 2 2 1 NACHT domain ANAPC4_WD40 PF12894.7 KXX77173.1 - 2.8e-05 24.3 0.0 2.2 8.6 0.0 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX77173.1 - 8.6e-05 23.2 0.1 0.0072 17.2 0.0 3.7 2 0 0 2 2 2 1 WD domain, G-beta repeat PGAP1 PF07819.13 KXX77173.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXX77173.1 - 0.00021 22.0 0.3 0.00093 19.9 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXX77173.1 - 0.0042 16.6 0.0 0.0099 15.4 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NB-ARC PF00931.22 KXX77173.1 - 0.033 13.4 0.1 0.13 11.4 0.1 1.9 1 1 0 1 1 1 0 NB-ARC domain HET PF06985.11 KXX77175.1 - 1.6e-28 99.9 0.0 2.9e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hemerythrin PF01814.23 KXX77176.1 - 8.5e-11 42.6 0.1 1.2e-10 42.2 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_TAC_8 PF10666.9 KXX77176.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 KTI12 PF08433.10 KXX77177.1 - 1.8e-65 221.1 0.0 3.1e-65 220.4 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KXX77177.1 - 0.0001 22.5 0.1 0.00035 20.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX77177.1 - 0.00082 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX77177.1 - 0.0019 18.6 0.1 0.0035 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain 6PF2K PF01591.18 KXX77177.1 - 0.006 15.9 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 KXX77177.1 - 0.024 15.2 1.3 0.04 14.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 KXX77177.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KXX77177.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Fungal_trans_2 PF11951.8 KXX77178.1 - 8.2e-12 44.6 0.5 9.3e-07 28.0 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX77178.1 - 9.8e-08 32.0 10.9 2.5e-07 30.7 10.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PALP PF00291.25 KXX77179.1 - 8.9e-49 166.5 0.0 1e-48 166.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.7 KXX77180.1 - 1.1e-25 90.0 0.2 3e-14 53.3 0.0 3.9 3 1 0 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77180.1 - 1.6e-21 76.3 0.3 2.6e-07 31.0 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KXX77180.1 - 6.5e-19 67.5 2.4 0.008 16.6 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KXX77180.1 - 1.3e-16 59.0 0.2 0.37 11.5 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXX77180.1 - 1.8e-10 40.9 0.5 0.044 14.1 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.12 KXX77180.1 - 6.1e-05 23.0 0.1 0.00026 21.0 0.0 2.2 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KXX77180.1 - 0.003 17.9 0.1 0.03 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX77180.1 - 0.028 14.7 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KXX77180.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KXX77180.1 - 0.094 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KXX77180.1 - 0.15 12.1 0.0 0.9 9.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXX77180.1 - 0.19 12.0 0.1 0.63 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 KXX77181.1 - 8.7e-19 67.9 2.6 1.7e-09 38.1 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77181.1 - 2.4e-14 53.5 0.8 9.4e-06 26.1 0.1 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77181.1 - 1.1e-13 50.0 0.5 0.0092 16.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KXX77181.1 - 1.7e-13 50.3 4.7 0.031 14.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXX77181.1 - 7e-08 32.6 1.6 0.15 12.4 0.1 3.8 3 1 0 3 3 3 3 Ankyrin repeats (many copies) RecR PF02132.15 KXX77181.1 - 0.012 15.1 0.6 0.012 15.1 0.6 2.1 1 1 0 1 1 1 0 RecR protein DZR PF12773.7 KXX77181.1 - 0.076 13.0 3.4 0.19 11.8 3.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KXX77181.1 - 0.23 11.2 5.6 0.11 12.3 2.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain C1_2 PF03107.16 KXX77181.1 - 1.6 9.1 7.3 4 7.8 7.3 1.6 1 1 0 1 1 1 0 C1 domain DUF1843 PF08898.10 KXX77181.1 - 4.2 8.0 8.1 11 6.7 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Dehydratase_hem PF13816.6 KXX77182.1 - 5.9e-114 380.6 0.0 6.6e-114 380.5 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 KXX77182.1 - 5.6e-06 26.7 0.0 0.002 18.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Peptidase_M41 PF01434.18 KXX77185.1 - 3.5e-56 190.1 0.2 6.9e-56 189.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXX77185.1 - 1e-42 145.7 0.0 2.7e-42 144.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX77185.1 - 8.4e-10 38.3 1.2 1.3e-09 37.7 0.1 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KXX77185.1 - 2.2e-05 24.9 0.1 0.00017 22.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KXX77185.1 - 4.8e-05 22.7 0.0 9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KXX77185.1 - 4.9e-05 23.4 0.2 0.00022 21.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX77185.1 - 0.00081 19.7 0.2 0.012 15.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXX77185.1 - 0.00088 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXX77185.1 - 0.0012 19.0 0.0 0.0049 17.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXX77185.1 - 0.011 15.4 0.6 0.73 9.4 0.3 2.6 1 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXX77185.1 - 0.014 15.1 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein SpoU_sub_bind PF08032.12 KXX77185.1 - 0.018 15.3 0.0 6.1 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Mg_chelatase PF01078.21 KXX77185.1 - 0.021 14.2 0.3 0.058 12.8 0.3 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KXX77185.1 - 0.029 13.7 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_2 PF07724.14 KXX77185.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KXX77185.1 - 0.13 11.8 0.1 0.45 10.0 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXX77185.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXX77185.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXX77185.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXX77185.1 - 0.16 11.2 1.3 0.66 9.2 0.4 2.3 1 1 1 2 2 2 0 Zeta toxin TsaE PF02367.17 KXX77185.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TetR_C_6 PF13977.6 KXX77185.1 - 1.1 9.5 3.4 14 6.0 0.4 2.7 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Steroid_dh PF02544.16 KXX77186.1 - 1.3e-21 77.1 0.6 6e-21 75.0 0.6 1.9 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXX77186.1 - 0.00024 20.7 0.3 0.00045 19.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) SfLAP PF11139.8 KXX77186.1 - 0.014 14.9 0.7 0.022 14.2 0.7 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF2150 PF09920.9 KXX77187.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) MINDY_DUB PF04424.13 KXX77188.1 - 1.3e-26 92.9 0.0 2.1e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Macoilin PF09726.9 KXX77188.1 - 3.1 6.3 6.9 4.9 5.6 6.9 1.2 1 0 0 1 1 1 0 Macoilin family ORC6 PF05460.13 KXX77189.1 - 4.2e-40 138.1 0.0 9.4e-40 137.0 0.0 1.5 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Epimerase PF01370.21 KXX77190.1 - 1.3e-15 57.5 0.0 1.9e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX77190.1 - 1.8e-13 50.2 0.0 2.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXX77190.1 - 5.8e-10 38.8 0.0 1.1e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXX77190.1 - 4.9e-09 36.3 0.1 1.3e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXX77190.1 - 4.1e-08 33.0 0.0 6.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KXX77190.1 - 8e-06 26.4 0.0 2.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KXX77190.1 - 4.1e-05 22.9 0.0 6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KXX77190.1 - 0.0016 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXX77190.1 - 0.0027 17.2 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KXX77190.1 - 0.0068 16.0 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family PHO4 PF01384.20 KXX77191.1 - 1.3e-109 366.4 9.0 1.4e-109 366.2 9.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 KXX77191.1 - 0.0012 19.2 0.0 0.016 15.6 0.0 3.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 KXX77191.1 - 0.18 12.2 0.2 0.18 12.2 0.2 3.0 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 EthD PF07110.11 KXX77193.1 - 3.2e-07 31.4 0.0 4.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 EthD domain CN_hydrolase PF00795.22 KXX77194.1 - 5.3e-37 127.6 0.3 6.9e-37 127.2 0.3 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ufd2P_core PF10408.9 KXX77196.1 - 1.8e-223 743.7 6.0 2.2e-223 743.4 6.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KXX77196.1 - 1.1e-22 79.9 0.4 3.2e-22 78.5 0.4 1.9 1 0 0 1 1 1 1 U-box domain LXG PF04740.12 KXX77196.1 - 0.094 12.4 0.6 0.23 11.1 0.6 1.6 1 0 0 1 1 1 0 LXG domain of WXG superfamily zf-TRAF PF02176.18 KXX77197.1 - 5e-13 49.5 28.3 2.8e-07 31.1 7.0 3.7 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 KXX77197.1 - 1.4e-09 37.6 3.6 1.4e-09 37.6 3.6 3.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX77197.1 - 1e-08 34.9 8.0 1e-08 34.9 8.0 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX77197.1 - 1.4e-08 34.6 10.6 1.4e-08 34.6 10.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXX77197.1 - 1e-07 32.1 6.5 1e-07 32.1 6.5 3.9 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KXX77197.1 - 1.3e-07 31.5 5.3 1.3e-07 31.5 5.3 3.4 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXX77197.1 - 4.1e-07 29.8 7.2 4.1e-07 29.8 7.2 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXX77197.1 - 4.5e-07 29.9 7.1 4.5e-07 29.9 7.1 2.5 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXX77197.1 - 4.7e-05 23.2 5.1 4.7e-05 23.2 5.1 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXX77197.1 - 0.00026 21.2 5.1 0.00026 21.2 5.1 3.3 3 2 1 4 4 1 1 RING-H2 zinc finger domain U-box PF04564.15 KXX77197.1 - 0.0042 17.2 0.6 0.011 15.9 0.2 1.9 2 0 0 2 2 1 1 U-box domain zf-RING_10 PF16685.5 KXX77197.1 - 0.011 15.8 2.8 0.011 15.8 2.8 2.6 2 1 0 3 3 2 0 zinc RING finger of MSL2 Muted PF14942.6 KXX77197.1 - 0.32 11.4 2.0 0.62 10.4 2.0 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein zf_UBZ PF18439.1 KXX77197.1 - 1.2 8.8 6.6 19 5.0 0.1 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-RING_4 PF14570.6 KXX77197.1 - 3.6 7.5 15.1 0.28 11.0 0.9 3.8 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain COesterase PF00135.28 KXX77198.1 - 8.7e-81 272.3 0.1 1.4e-71 242.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX77198.1 - 3e-12 46.9 0.2 4.8e-12 46.2 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX77198.1 - 0.0044 17.7 6.3 0.0075 16.9 5.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family SCF PF02404.15 KXX77200.1 - 0.014 14.8 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor Pex14_N PF04695.13 KXX77200.1 - 0.13 13.0 7.1 0.17 12.6 5.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FTR1 PF03239.14 KXX77200.1 - 0.26 10.4 0.6 0.31 10.2 0.6 1.3 1 1 0 1 1 1 0 Iron permease FTR1 family MAP65_ASE1 PF03999.12 KXX77200.1 - 3.9 6.1 5.9 4 6.0 5.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) His_Phos_1 PF00300.22 KXX77201.1 - 5.5e-35 120.8 3.0 8.6e-33 113.7 3.0 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PMT PF02366.18 KXX77202.1 - 1.6e-77 260.4 16.5 2.8e-77 259.6 16.5 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXX77202.1 - 9.4e-67 224.5 10.6 9.4e-67 224.5 10.6 2.3 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXX77202.1 - 4e-49 167.0 0.0 7.4e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.8 KXX77203.1 - 1.2e-58 198.6 10.9 3.7e-58 197.0 10.9 1.8 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KXX77203.1 - 4.2e-36 122.7 0.7 6.2e-17 61.3 0.2 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KXX77203.1 - 0.002 17.7 0.5 0.0035 16.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Orbi_VP6 PF01516.16 KXX77203.1 - 0.0076 15.8 0.6 0.7 9.4 1.4 2.3 2 0 0 2 2 2 1 Orbivirus helicase VP6 Cu-oxidase PF00394.22 KXX77203.1 - 0.11 12.6 0.0 0.61 10.2 0.0 2.2 1 1 0 1 1 1 0 Multicopper oxidase DUF1682 PF07946.14 KXX77203.1 - 6.1 6.0 15.6 0.035 13.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Eapp_C PF10238.9 KXX77203.1 - 8.4 6.5 8.8 3.6 7.6 1.5 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein PX PF00787.24 KXX77204.1 - 3.8e-25 88.1 0.0 5.7e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 KXX77205.1 - 6.7e-75 247.1 2.0 1.8e-24 85.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXX77205.1 - 0.048 12.8 4.8 2.2 7.3 0.3 3.7 1 1 3 4 4 4 0 Gammaproteobacterial serine protease HMD PF03201.16 KXX77205.1 - 0.074 13.3 0.0 1.6 9.0 0.0 2.7 3 1 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase ARPC4 PF05856.12 KXX77206.1 - 1.3e-80 268.9 4.0 1.5e-80 268.7 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 KXX77207.1 - 6.3e-52 176.6 0.0 8e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX77207.1 - 2.2e-14 53.8 4.6 6.3e-13 49.0 4.6 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KXX77207.1 - 1.1e-12 47.5 1.1 1.9e-12 46.7 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin family NB-ARC PF00931.22 KXX77208.1 - 1.6e-15 57.0 0.0 4.3e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_12 PF13424.6 KXX77208.1 - 1.9e-11 44.1 19.5 0.0015 18.7 0.8 5.1 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX77208.1 - 4.5e-09 36.1 5.0 7.9e-09 35.3 5.0 1.3 1 0 0 1 1 1 1 MalT-like TPR region AAA_16 PF13191.6 KXX77208.1 - 7e-08 33.0 1.4 2.9e-07 31.0 0.1 2.8 2 2 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.17 KXX77208.1 - 3.4e-07 29.9 18.6 0.078 13.1 0.9 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXX77208.1 - 5.1e-05 23.0 17.9 1.1 9.3 0.1 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX77208.1 - 9.8e-05 22.9 17.4 0.3 12.0 0.1 6.6 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX77208.1 - 0.0022 18.6 19.6 0.38 11.4 0.9 5.6 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXX77208.1 - 0.0032 17.7 3.3 0.74 10.3 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX77208.1 - 0.0066 16.4 6.4 4.8 7.4 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXX77208.1 - 0.0099 15.7 12.8 0.17 11.7 0.9 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat AAA_22 PF13401.6 KXX77208.1 - 0.018 15.3 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_9 PF13371.6 KXX77208.1 - 0.018 15.2 8.3 0.98 9.6 0.4 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXX77208.1 - 0.023 15.3 9.4 6.8 7.6 0.2 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXX77208.1 - 0.027 15.0 6.0 0.63 10.6 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat FRB_dom PF08771.11 KXX77208.1 - 0.078 13.4 0.0 20 5.7 0.0 3.9 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain TniB PF05621.11 KXX77208.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ANAPC3 PF12895.7 KXX77208.1 - 0.23 11.7 4.3 2 8.7 0.1 3.9 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXX77208.1 - 0.48 10.8 10.9 0.96 9.8 0.4 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Beta-lactamase PF00144.24 KXX77210.1 - 2.4e-42 145.4 0.2 3.1e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Pan3_PK PF18101.1 KXX77211.1 - 1.7e-51 173.9 0.1 2.5e-51 173.3 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KXX77211.1 - 4.1e-06 26.3 0.0 7.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77211.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase UBA_4 PF14555.6 KXX77212.1 - 2.6e-10 39.9 0.0 5.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXX77212.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain NYD-SP28 PF14772.6 KXX77212.1 - 0.13 12.3 10.9 0.33 11.0 10.9 1.7 1 0 0 1 1 1 0 Sperm tail D5_N PF08706.11 KXX77212.1 - 0.18 12.0 0.6 0.36 11.1 0.6 1.5 1 0 0 1 1 1 0 D5 N terminal like GAT PF03127.14 KXX77213.1 - 4.1e-18 65.5 0.2 8.9e-18 64.4 0.2 1.6 1 0 0 1 1 1 1 GAT domain DnaG_DnaB_bind PF08278.11 KXX77213.1 - 0.043 14.4 0.5 0.1 13.2 0.5 1.6 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding VHS PF00790.19 KXX77213.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 VHS domain LMBR1 PF04791.16 KXX77213.1 - 0.2 10.5 0.1 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Zn_clus PF00172.18 KXX77214.1 - 7.2e-08 32.4 7.7 1.1e-07 31.8 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KXX77215.1 - 8.9e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77215.1 - 2.5e-12 47.3 0.1 1.2e-11 45.1 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77215.1 - 3.5e-12 46.9 0.0 1.7e-11 44.7 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX77215.1 - 3.5e-10 39.9 0.0 9e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77215.1 - 1.2e-08 35.6 0.0 9.5e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX77215.1 - 3.3e-06 26.6 0.0 8.4e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KXX77215.1 - 0.0048 16.9 0.0 0.013 15.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KXX77215.1 - 0.027 13.8 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltrans_SAM PF10672.9 KXX77215.1 - 0.042 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase DREV PF05219.12 KXX77215.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 KXX77215.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Choline_kinase PF01633.20 KXX77216.1 - 0.00046 19.8 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KXX77216.1 - 0.0018 17.2 0.0 0.0059 15.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KXX77216.1 - 0.0044 16.4 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77216.1 - 0.053 12.8 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase ATP-synt_ab PF00006.25 KXX77217.1 - 1.4e-108 361.5 0.0 1.8e-108 361.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KXX77217.1 - 4.7e-48 162.1 0.0 1e-47 161.0 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KXX77217.1 - 8.1e-15 55.1 4.1 1.9e-14 53.9 4.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Trm112p PF03966.16 KXX77219.1 - 1.5e-13 51.1 0.0 1e-12 48.5 0.0 1.9 1 1 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 KXX77219.1 - 0.022 15.2 0.4 0.035 14.6 0.4 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-BED PF02892.15 KXX77219.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger Ras PF00071.22 KXX77220.1 - 1.5e-31 109.2 0.3 1.9e-31 108.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX77220.1 - 7.9e-24 84.2 0.1 1.4e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX77220.1 - 4.4e-07 29.5 0.1 6e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXX77220.1 - 0.0001 21.7 0.2 0.00014 21.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KXX77220.1 - 0.00075 18.4 0.3 0.05 12.4 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) DUF4048 PF13257.6 KXX77221.1 - 2.5e-16 60.3 23.0 4.4e-15 56.2 11.3 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 KXX77221.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain N-SET PF11764.8 KXX77222.1 - 4e-54 183.3 0.4 4e-54 183.3 0.4 3.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KXX77222.1 - 5e-28 96.5 3.1 5.2e-28 96.5 1.0 2.2 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated SET PF00856.28 KXX77222.1 - 1.9e-20 73.9 0.2 1.9e-20 73.9 0.2 3.3 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 KXX77222.1 - 0.16 11.8 0.2 21 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop25 PF09805.9 KXX77223.1 - 4.4e-41 140.6 13.7 4.4e-41 140.6 13.7 2.2 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Sun2_CC2 PF18580.1 KXX77223.1 - 0.077 13.2 1.6 0.077 13.2 1.6 2.3 2 1 0 2 2 2 0 SUN2 coiled coil domain 2 Tropomyosin_1 PF12718.7 KXX77224.1 - 4.3e-54 182.6 33.1 5e-54 182.3 33.1 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KXX77224.1 - 2.1e-07 30.6 32.9 0.00013 21.5 7.9 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.9 KXX77224.1 - 1.2e-05 25.3 32.1 0.0013 18.8 4.4 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KXX77224.1 - 0.00063 20.0 32.1 0.61 10.3 12.6 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 KXX77224.1 - 0.00069 19.6 19.6 0.005 16.8 3.3 2.1 1 1 1 2 2 2 2 Laminin Domain II KLRAQ PF10205.9 KXX77224.1 - 0.0022 18.2 21.8 0.087 13.1 7.0 3.2 1 1 2 3 3 3 2 Predicted coiled-coil domain-containing protein DUF4200 PF13863.6 KXX77224.1 - 0.0024 18.3 34.0 0.079 13.4 14.0 2.6 2 2 0 2 2 2 2 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.13 KXX77224.1 - 0.0024 18.2 35.4 0.12 12.8 14.1 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region Jnk-SapK_ap_N PF09744.9 KXX77224.1 - 0.0027 17.9 20.1 0.0027 17.9 20.1 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 HMMR_C PF15908.5 KXX77224.1 - 0.0032 17.8 18.7 0.0078 16.5 3.8 3.1 1 1 1 3 3 3 1 Hyaluronan mediated motility receptor C-terminal DUF724 PF05266.14 KXX77224.1 - 0.0036 17.2 24.6 0.021 14.6 7.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF724) DivIC PF04977.15 KXX77224.1 - 0.0085 15.8 3.5 0.0085 15.8 3.5 4.3 1 1 2 4 4 4 1 Septum formation initiator DUF1664 PF07889.12 KXX77224.1 - 0.0096 16.0 15.6 0.035 14.1 2.6 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KXX77224.1 - 0.015 15.8 10.5 0.25 11.8 3.5 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KXX77224.1 - 0.016 14.1 33.3 0.034 13.0 13.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KXX77224.1 - 0.021 14.2 31.9 0.081 12.3 12.9 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KXX77224.1 - 0.026 14.8 25.1 0.32 11.2 15.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KXX77224.1 - 0.046 14.3 39.6 0.05 14.1 24.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-K PF11802.8 KXX77224.1 - 0.047 13.3 20.5 1.2 8.6 20.4 2.0 1 1 0 1 1 1 0 Centromere-associated protein K CASP_C PF08172.12 KXX77224.1 - 0.051 12.9 17.3 0.11 11.9 1.5 2.2 2 0 0 2 2 2 0 CASP C terminal Syntaxin-6_N PF09177.11 KXX77224.1 - 0.056 14.0 18.5 1.3 9.6 6.5 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ERM PF00769.19 KXX77224.1 - 0.059 13.2 37.3 0.13 12.1 16.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family EzrA PF06160.12 KXX77224.1 - 0.067 11.4 23.0 0.29 9.3 7.1 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ADIP PF11559.8 KXX77224.1 - 0.07 13.2 29.5 0.24 11.5 8.4 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 KXX77224.1 - 0.071 12.8 32.2 0.25 11.0 17.1 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 KXX77224.1 - 0.073 13.5 17.9 1.3 9.4 4.1 4.3 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.11 KXX77224.1 - 0.074 11.9 30.4 0.67 8.7 16.8 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Taxilin PF09728.9 KXX77224.1 - 0.075 12.2 30.6 0.23 10.6 30.6 1.7 1 1 0 1 1 1 0 Myosin-like coiled-coil protein MbeD_MobD PF04899.12 KXX77224.1 - 0.081 13.1 11.7 1.4 9.1 0.4 2.9 2 2 1 3 3 3 0 MbeD/MobD like HALZ PF02183.18 KXX77224.1 - 0.091 13.0 0.5 0.091 13.0 0.5 4.9 5 1 1 6 6 5 0 Homeobox associated leucine zipper Fez1 PF06818.15 KXX77224.1 - 0.1 13.0 26.5 0.15 12.5 26.3 1.4 1 1 0 1 1 1 0 Fez1 DUF3450 PF11932.8 KXX77224.1 - 0.12 11.6 28.0 0.51 9.6 12.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 KXX77224.1 - 0.13 12.5 28.4 0.73 10.1 10.9 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 KXX77224.1 - 0.13 12.3 30.3 0.52 10.4 7.3 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 KXX77224.1 - 0.14 11.6 28.3 0.2 11.1 28.3 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 KXX77224.1 - 0.15 12.1 34.9 0.18 11.8 14.6 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 KXX77224.1 - 0.22 11.7 25.0 2.3 8.5 1.6 4.3 1 1 4 5 5 5 0 Haemolysin XhlA Filament PF00038.21 KXX77224.1 - 0.22 11.1 25.1 1.6 8.3 9.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.9 KXX77224.1 - 0.25 11.7 24.1 1.8 8.9 0.9 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 KXX77224.1 - 0.32 11.4 14.1 7.8 7.0 0.1 3.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF4686 PF15742.5 KXX77224.1 - 0.36 9.9 31.4 0.19 10.8 22.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) bZIP_1 PF00170.21 KXX77224.1 - 0.38 10.9 29.0 1.4 9.1 2.6 4.8 2 1 3 5 5 5 0 bZIP transcription factor YabA PF06156.13 KXX77224.1 - 0.38 11.4 20.2 19 6.0 14.0 2.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 KXX77224.1 - 0.4 11.2 23.6 0.27 11.8 4.7 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 KELK PF15796.5 KXX77224.1 - 0.43 11.1 32.9 0.071 13.6 4.1 3.9 2 2 1 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SHE3 PF17078.5 KXX77224.1 - 0.47 10.1 22.1 1.2 8.8 6.1 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FapA PF03961.13 KXX77224.1 - 0.59 8.7 25.9 0.5 8.9 8.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Lge1 PF11488.8 KXX77224.1 - 0.63 10.3 17.1 1.3 9.3 2.7 3.9 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF2203 PF09969.9 KXX77224.1 - 0.64 10.7 19.5 0.9 10.3 5.0 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.6 KXX77224.1 - 0.73 9.1 22.1 1.6 8.0 22.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 KXX77224.1 - 0.78 9.7 32.2 1.9 8.4 4.1 3.8 1 1 2 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 KXX77224.1 - 0.86 9.9 21.3 22 5.3 12.9 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Alanine_zipper PF11839.8 KXX77224.1 - 0.96 9.9 15.6 0.1 13.0 2.4 3.5 1 1 2 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein CENP-H PF05837.12 KXX77224.1 - 1 9.8 25.8 4.2 7.8 0.2 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) HOOK PF05622.12 KXX77224.1 - 1.1 7.3 28.4 1.9 6.5 28.4 1.4 1 1 0 1 1 1 0 HOOK protein MAD PF05557.13 KXX77224.1 - 1.2 7.4 28.9 2.1 6.6 28.9 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein KASH_CCD PF14662.6 KXX77224.1 - 1.4 8.7 31.2 1.4 8.7 18.5 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH VGPC1_C PF16799.5 KXX77224.1 - 1.4 8.9 12.5 0.67 10.0 0.7 3.7 3 2 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF4472 PF14739.6 KXX77224.1 - 1.6 9.5 27.3 2.8 8.7 8.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Cortex-I_coil PF09304.10 KXX77224.1 - 1.6 8.9 23.1 5.2 7.3 8.6 3.4 1 1 2 3 3 3 0 Cortexillin I, coiled coil TPR_MLP1_2 PF07926.12 KXX77224.1 - 1.7 8.7 37.0 0.67 10.0 12.3 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 KXX77224.1 - 1.9 8.6 31.4 5.3 7.1 14.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 KXX77224.1 - 2 8.5 34.3 6.7 6.8 13.9 2.8 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4201 PF13870.6 KXX77224.1 - 2.2 8.0 24.7 1.4e+02 2.1 24.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TRAF_BIRC3_bd PF16673.5 KXX77224.1 - 2.7 7.8 18.7 5.2 6.9 0.7 3.9 2 2 3 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain DUF3584 PF12128.8 KXX77224.1 - 3 5.3 26.3 4 4.8 26.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.9 KXX77224.1 - 3.2 6.5 24.1 0.086 11.7 9.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain BRI3BP PF14965.6 KXX77224.1 - 3.3 7.2 8.3 1.1 8.7 0.3 3.1 3 1 0 3 3 3 0 Negative regulator of p53/TP53 Sec34 PF04136.15 KXX77224.1 - 3.8 7.4 16.9 0.44 10.4 4.3 2.4 1 1 0 2 2 2 0 Sec34-like family Spc24 PF08286.11 KXX77224.1 - 4.7 7.5 28.4 4.6 7.5 10.4 3.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KXX77224.1 - 5.3 7.2 36.0 0.17 12.0 0.8 5.3 2 1 3 5 5 4 0 Basic region leucine zipper T2SSM PF04612.12 KXX77224.1 - 5.3 7.1 17.4 0.86 9.6 0.5 3.1 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M Fib_alpha PF08702.10 KXX77224.1 - 5.5 7.2 17.4 5.4 7.2 3.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KXX77224.1 - 6 5.3 10.2 8.9 4.7 10.2 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family HAUS-augmin3 PF14932.6 KXX77224.1 - 6.4 6.3 29.1 9.9 5.7 11.9 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 ZapB PF06005.12 KXX77224.1 - 6.4 7.3 39.0 16 6.0 5.7 4.3 1 1 2 3 3 2 0 Cell division protein ZapB KxDL PF10241.9 KXX77224.1 - 6.5 7.1 20.0 2.3 8.6 0.8 3.8 1 1 3 4 4 4 0 Uncharacterized conserved protein DUF948 PF06103.11 KXX77224.1 - 8.4 6.7 12.7 31 4.9 2.4 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rota_NSP3 PF01665.16 KXX77224.1 - 8.5 5.4 12.0 5.3 6.1 1.1 2.1 1 1 1 2 2 2 0 Rotavirus non-structural protein NSP3 MPS2 PF17060.5 KXX77224.1 - 8.9 5.5 15.8 19 4.4 15.4 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 Nsp1_C PF05064.13 KXX77224.1 - 9.1 6.1 20.7 0.32 10.8 5.3 2.6 1 1 2 3 3 3 0 Nsp1-like C-terminal region Cep57_MT_bd PF06657.13 KXX77224.1 - 9.1 6.8 24.0 1.9 9.0 2.4 3.8 1 1 3 4 4 3 0 Centrosome microtubule-binding domain of Cep57 Apc13p PF05839.11 KXX77225.1 - 6.4e-35 119.2 0.0 8.2e-35 118.9 0.0 1.1 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.16 KXX77226.1 - 1.5e-37 128.6 0.0 2e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pro_isomerase PF00160.21 KXX77227.1 - 1.3e-49 168.5 0.5 1.6e-49 168.2 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Syntaxin-6_N PF09177.11 KXX77228.1 - 5.6e-26 91.0 1.0 1.5e-25 89.7 0.2 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KXX77228.1 - 0.00027 20.9 0.8 0.00054 19.9 0.8 1.5 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 KXX77228.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 UPF0242 PF06785.11 KXX77228.1 - 0.15 12.2 3.0 4.4 7.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG17 PF04108.12 KXX77228.1 - 0.17 10.9 2.6 7.3 5.6 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF4164 PF13747.6 KXX77228.1 - 0.96 9.8 7.0 0.3 11.4 1.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Ferritin_2 PF13668.6 KXX77229.1 - 9.7e-39 132.7 1.1 1.7e-38 131.9 1.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain LIME1 PF15332.6 KXX77229.1 - 0.025 14.2 0.4 0.047 13.3 0.4 1.4 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 NUT PF12881.7 KXX77229.1 - 0.31 9.4 1.1 0.43 9.0 1.1 1.1 1 0 0 1 1 1 0 NUT protein ELFV_dehydrog PF00208.21 KXX77230.1 - 2.2e-79 266.6 2.0 2.7e-79 266.4 2.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KXX77230.1 - 1e-49 167.7 0.0 2e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KXX77230.1 - 0.009 16.4 0.1 0.02 15.3 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding GLE1 PF07817.13 KXX77231.1 - 5.8e-60 202.6 0.0 7.6e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 GLE1-like protein CAF-1_p150 PF11600.8 KXX77231.1 - 4.3 7.0 15.7 8.3 6.1 15.7 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNB PF00773.19 KXX77232.1 - 6.3e-78 262.4 0.0 1.1e-77 261.6 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KXX77232.1 - 8e-27 93.1 0.1 2.7e-26 91.4 0.0 2.0 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KXX77232.1 - 1.9e-25 89.0 0.0 7.7e-25 87.0 0.0 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KXX77232.1 - 6e-07 29.6 0.0 0.0028 17.8 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KXX77232.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain DUF4239 PF14023.6 KXX77232.1 - 0.15 11.7 0.4 0.3 10.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) ATP-synt_S1 PF05827.12 KXX77233.1 - 3.5e-05 23.7 0.1 6.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) TIP120 PF08623.10 KXX77234.1 - 6.9e-75 250.4 3.8 2.3e-70 235.7 0.1 4.0 4 1 0 4 4 3 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KXX77234.1 - 1.1e-15 57.7 16.7 0.0064 16.9 0.1 8.7 8 2 3 11 11 10 5 HEAT repeats HEAT PF02985.22 KXX77234.1 - 1.6e-11 43.4 27.1 0.15 12.4 0.1 11.3 13 1 1 14 14 10 4 HEAT repeat Cnd1 PF12717.7 KXX77234.1 - 1.4e-09 38.2 11.1 0.032 14.3 0.2 6.5 5 2 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXX77234.1 - 2.8e-07 30.9 24.3 5.1 7.7 0.0 13.1 13 2 1 14 14 14 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KXX77234.1 - 5.6e-07 30.1 0.5 0.52 10.9 0.0 7.4 7 3 2 9 9 7 1 Vacuolar 14 Fab1-binding region DRIM PF07539.12 KXX77234.1 - 4.8e-06 25.2 3.1 5.9e-05 21.6 0.8 3.3 3 1 0 3 3 3 1 Down-regulated in metastasis Adaptin_N PF01602.20 KXX77234.1 - 9.6e-06 24.4 13.9 0.012 14.2 0.2 6.5 6 2 1 8 8 8 2 Adaptin N terminal region RTP1_C1 PF10363.9 KXX77234.1 - 1.1e-05 25.6 9.4 0.06 13.5 0.0 5.6 7 0 0 7 7 6 2 Required for nuclear transport of RNA pol II C-terminus 1 VHS PF00790.19 KXX77234.1 - 0.00019 21.3 0.0 0.39 10.6 0.0 3.0 2 0 0 2 2 2 2 VHS domain CLASP_N PF12348.8 KXX77234.1 - 0.0012 18.4 2.2 0.23 11.0 0.0 4.3 3 1 1 4 4 4 1 CLASP N terminal Cnd3 PF12719.7 KXX77234.1 - 0.0079 15.4 0.1 4.8 6.3 0.0 3.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DCB PF16213.5 KXX77234.1 - 0.027 14.2 3.3 0.12 12.1 0.5 3.5 4 0 0 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 RIX1 PF08167.12 KXX77234.1 - 0.039 13.7 4.3 9 6.0 0.0 4.7 4 2 0 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.23 KXX77234.1 - 0.048 13.7 3.5 23 5.2 0.1 5.7 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KXX77234.1 - 0.092 11.8 2.9 13 4.8 0.1 4.2 5 1 0 5 5 5 0 Interferon-related developmental regulator (IFRD) DUF3361 PF11841.8 KXX77234.1 - 0.32 10.9 1.5 2.5 8.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Presenilin PF01080.17 KXX77235.1 - 0.48 9.1 14.9 0.58 8.9 14.9 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KXX77235.1 - 1.1 9.0 7.3 9.7 5.9 7.3 2.0 1 1 0 1 1 1 0 Connexin Porphobil_deam PF01379.20 KXX77236.1 - 1.4e-72 243.5 0.0 1.8e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KXX77236.1 - 3.7e-19 68.9 1.2 6.6e-19 68.1 1.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.19 KXX77237.1 - 2.4e-32 111.4 0.6 2.9e-32 111.1 0.6 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Tmemb_9 PF05434.11 KXX77238.1 - 9.5 6.1 8.0 21 5.0 6.8 1.8 1 1 1 2 2 2 0 TMEM9 BRCT PF00533.26 KXX77240.1 - 7.2e-05 23.1 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXX77240.1 - 0.00037 20.3 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KXX77240.1 - 0.0067 16.8 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SNURF PF07192.11 KXX77240.1 - 0.12 12.3 0.5 0.99 9.3 0.0 2.6 2 0 0 2 2 2 0 SNURF/RPN4 protein BRCT_3 PF18428.1 KXX77240.1 - 0.2 11.7 0.0 32 4.7 0.0 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain CoA_binding_2 PF13380.6 KXX77241.1 - 5.3e-27 94.6 0.0 6.3e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain GTP1_OBG PF01018.22 KXX77241.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 GTP1/OBG DUF3716 PF12511.8 KXX77242.1 - 2e-19 69.4 7.6 4.1e-15 55.6 3.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) NOA36 PF06524.12 KXX77242.1 - 0.0031 16.9 16.1 0.0063 15.9 16.1 1.4 1 0 0 1 1 1 1 NOA36 protein GEN1_C PF18380.1 KXX77242.1 - 0.06 14.3 0.7 0.29 12.1 0.7 2.2 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain CENP-C_C PF11699.8 KXX77242.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like zf-C2H2_4 PF13894.6 KXX77242.1 - 3.6 8.7 10.2 6.9 7.8 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger GCIP PF13324.6 KXX77242.1 - 4.4 6.8 6.8 9.7 5.7 6.8 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM176 PF14851.6 KXX77242.1 - 5.8 6.6 5.0 21 4.8 5.0 2.0 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 KXX77242.1 - 8.9 6.3 10.1 25 4.9 10.1 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal SH3_1 PF00018.28 KXX77243.1 - 1.7e-27 94.8 0.0 1.1e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KXX77243.1 - 7.1e-19 67.4 0.5 1e-09 38.1 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 KXX77243.1 - 9e-15 54.7 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KXX77243.1 - 3.2e-13 49.1 0.0 3.6e-08 32.9 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KXX77243.1 - 2e-08 34.0 0.0 3.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.16 KXX77244.1 - 7.3e-27 94.5 5.4 7.5e-25 87.9 5.4 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXX77244.1 - 0.0019 18.2 0.2 0.0041 17.1 0.2 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HTH_ABP1_N PF18107.1 KXX77246.1 - 3.4e-25 87.5 1.1 9.1e-25 86.2 1.1 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 KXX77246.1 - 2.9e-17 62.4 1.9 2.8e-16 59.3 0.2 3.0 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain SMBP PF16785.5 KXX77246.1 - 1.3 9.3 5.2 0.99 9.6 3.2 1.8 2 0 0 2 2 2 0 Small metal-binding protein ATP19 PF11022.8 KXX77247.1 - 1.4e-28 99.0 0.1 1.7e-28 98.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MTP18 PF10558.9 KXX77248.1 - 4.3e-82 274.2 0.0 5.5e-82 273.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) EAP30 PF04157.16 KXX77249.1 - 1.3e-45 155.5 0.0 1.7e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KXX77249.1 - 1.7e-24 85.8 0.0 3e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KXX77249.1 - 4.3e-24 83.7 2.6 4.3e-24 83.7 2.6 2.5 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KXX77249.1 - 0.0014 18.6 4.6 0.023 14.7 0.3 2.4 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GRAM PF02893.20 KXX77249.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 GRAM domain DUF35_N PF12172.8 KXX77249.1 - 0.097 12.6 0.6 0.22 11.4 0.6 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-RanBP PF00641.18 KXX77249.1 - 0.13 11.6 14.7 0.033 13.5 1.2 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.7 KXX77249.1 - 1.3 9.1 6.0 0.19 11.8 0.4 2.2 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 KXX77249.1 - 6.1 8.0 8.9 84 4.4 0.5 3.5 2 1 1 3 3 3 0 C2H2-type zinc finger Peptidase_M3 PF01432.20 KXX77251.1 - 5.8e-159 530.2 0.0 7.3e-159 529.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KXX77251.1 - 0.046 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Effector protein Peptidase_M2 PF01401.18 KXX77251.1 - 0.21 10.2 0.0 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Angiotensin-converting enzyme TPR_12 PF13424.6 KXX77252.1 - 2e-16 60.1 9.3 4.3e-11 42.9 1.3 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXX77252.1 - 1.6e-10 40.5 3.3 0.08 12.8 0.5 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXX77252.1 - 2.3e-06 27.1 1.3 3.3 7.7 0.2 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX77252.1 - 8.3e-06 26.2 0.0 0.023 15.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX77252.1 - 2.2e-05 24.3 0.6 4.4 7.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX77252.1 - 0.00027 20.8 5.6 0.3 11.3 1.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX77252.1 - 0.011 15.2 0.0 0.64 9.3 0.3 2.5 1 1 1 2 2 2 0 MalT-like TPR region TPR_3 PF07720.12 KXX77252.1 - 0.034 14.2 0.2 12 6.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 KXX77252.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF2225 PF09986.9 KXX77252.1 - 0.051 13.3 0.5 0.12 12.1 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.6 KXX77252.1 - 0.068 14.0 3.3 3.3 8.8 0.2 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat NB-ARC PF00931.22 KXX77252.1 - 0.12 11.6 0.0 8.2 5.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 KXX77252.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_7 PF13176.6 KXX77252.1 - 0.23 11.6 0.9 51 4.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4794 PF16042.5 KXX77254.1 - 0.46 11.5 3.8 4.8 8.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4794) AA_permease_2 PF13520.6 KXX77255.1 - 1.6e-67 228.2 38.2 2.1e-67 227.8 38.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX77255.1 - 7.8e-07 28.0 33.9 1.4e-06 27.2 33.9 1.4 1 1 0 1 1 1 1 Amino acid permease EF-hand_7 PF13499.6 KXX77257.1 - 6.3e-13 49.0 0.1 3.6e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KXX77257.1 - 2e-12 47.2 0.0 7.3e-06 26.2 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KXX77257.1 - 4.2e-10 38.7 0.5 0.006 16.4 0.0 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KXX77257.1 - 4.8e-10 38.3 0.2 0.016 14.7 0.0 4.0 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KXX77257.1 - 2.3e-09 36.9 0.1 2e-05 24.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair Amidase PF01425.21 KXX77258.1 - 4e-37 128.2 0.2 5.5e-36 124.5 0.2 2.0 1 1 0 1 1 1 1 Amidase ARL2_Bind_BART PF11527.8 KXX77258.1 - 0.084 13.0 1.8 7.6 6.7 0.1 2.4 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Rad4 PF03835.15 KXX77259.1 - 1.1e-34 119.2 0.2 4.1e-34 117.4 0.2 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXX77259.1 - 9.7e-29 99.6 0.3 2.3e-28 98.4 0.3 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KXX77259.1 - 4.7e-20 71.2 0.1 1.1e-19 70.0 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KXX77259.1 - 6.1e-16 59.1 0.5 6.1e-16 59.1 0.5 6.2 6 1 0 6 6 6 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KXX77259.1 - 0.00074 19.9 0.1 0.0038 17.7 0.0 2.4 2 1 0 2 2 2 1 Transglutaminase-like superfamily zf-AN1 PF01428.16 KXX77260.1 - 1.2e-25 89.4 23.8 2.2e-13 50.1 8.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KXX77260.1 - 0.047 13.9 18.9 0.14 12.4 3.5 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 KXX77260.1 - 1.4 9.3 15.4 0.64 10.4 6.5 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 KXX77260.1 - 5.7 7.3 16.1 21 5.4 8.5 3.1 2 1 0 2 2 2 0 TFIIH C1-like domain Dcc1 PF09724.9 KXX77261.1 - 1.8e-10 40.7 0.0 2.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 IBR PF01485.21 KXX77262.1 - 0.012 15.8 22.5 0.016 15.4 5.2 4.6 4 1 0 4 4 4 0 IBR domain, a half RING-finger domain PI31_Prot_N PF11566.8 KXX77263.1 - 3e-62 209.2 0.0 4.6e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KXX77263.1 - 1.5e-17 64.5 17.6 1.5e-17 64.5 17.6 3.7 3 1 1 4 4 4 1 PI31 proteasome regulator A_deaminase PF00962.22 KXX77264.1 - 1.9e-23 83.4 0.3 2.5e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KXX77264.1 - 0.00067 19.9 1.6 0.0026 18.0 1.5 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Herpes_UL4 PF03277.13 KXX77265.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF4133 PF13571.6 KXX77265.1 - 0.32 11.4 6.3 0.19 12.1 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) DUF2530 PF10745.9 KXX77265.1 - 0.37 11.1 3.8 0.9 9.8 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4131 PF13567.6 KXX77265.1 - 0.37 10.4 4.2 7.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2157 PF09925.9 KXX77265.1 - 0.47 10.2 6.0 4.8 7.0 6.0 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) PEX11 PF05648.14 KXX77266.1 - 3.9e-17 62.5 0.0 5.5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SRP40_C PF05022.12 KXX77267.1 - 4.1e-24 85.2 1.0 1.8e-23 83.2 1.0 2.2 1 0 0 1 1 1 1 SRP40, C-terminal domain ABC_tran PF00005.27 KXX77268.1 - 7.9e-50 168.9 0.9 2.7e-23 83.0 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KXX77268.1 - 7.2e-21 74.0 6.9 7.2e-21 74.0 6.9 4.2 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.6 KXX77268.1 - 7.5e-18 65.4 1.1 0.00017 21.5 0.0 4.6 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX77268.1 - 5.8e-10 39.0 7.2 0.0043 16.5 0.0 4.6 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KXX77268.1 - 3.9e-07 30.7 0.0 0.029 14.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KXX77268.1 - 7.8e-07 29.2 0.7 0.0088 16.1 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXX77268.1 - 2.9e-06 26.9 0.1 0.034 13.9 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXX77268.1 - 3.5e-06 27.0 1.7 0.034 14.1 0.1 3.2 2 1 1 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 KXX77268.1 - 7.7e-06 26.1 0.3 0.12 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KXX77268.1 - 1.1e-05 25.8 0.0 0.076 13.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KXX77268.1 - 2.1e-05 25.0 1.7 0.031 14.7 0.2 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 KXX77268.1 - 5.2e-05 23.8 17.5 0.03 14.8 0.0 4.9 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 KXX77268.1 - 0.00021 21.1 5.5 0.0058 16.4 0.0 3.6 4 1 0 4 4 4 1 AAA domain AAA PF00004.29 KXX77268.1 - 0.00026 21.4 0.0 0.46 10.9 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KXX77268.1 - 0.00027 20.8 10.2 0.23 11.1 0.0 4.7 4 1 0 5 5 5 2 AAA ATPase domain AAA_24 PF13479.6 KXX77268.1 - 0.0004 20.2 0.8 0.95 9.2 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KXX77268.1 - 0.0027 17.7 0.0 3 7.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXX77268.1 - 0.003 17.5 0.1 4.2 7.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain cobW PF02492.19 KXX77268.1 - 0.0038 16.8 0.4 1.1 8.8 0.4 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KXX77268.1 - 0.0055 16.2 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KXX77268.1 - 0.006 16.5 0.1 0.79 9.6 0.0 2.8 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KXX77268.1 - 0.0063 16.9 0.0 3.5 8.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase MeaB PF03308.16 KXX77268.1 - 0.0066 15.5 5.5 0.47 9.4 0.1 3.3 3 1 1 4 4 4 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KXX77268.1 - 0.013 14.8 1.1 1.4 8.2 0.1 3.5 3 0 0 3 3 3 0 Zeta toxin Halo_GVPC PF05465.13 KXX77268.1 - 0.014 15.7 0.6 0.085 13.1 0.4 2.4 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat AAA_28 PF13521.6 KXX77268.1 - 0.014 15.7 9.3 0.056 13.7 0.1 3.4 4 0 0 4 4 2 0 AAA domain ATP-synt_ab PF00006.25 KXX77268.1 - 0.014 15.0 0.1 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KXX77268.1 - 0.015 15.5 0.1 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 KXX77268.1 - 0.024 14.5 0.1 0.75 9.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KXX77268.1 - 0.026 14.5 0.3 6.8 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KXX77268.1 - 0.028 14.4 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXX77268.1 - 0.035 13.3 0.0 9.1 5.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 KXX77268.1 - 0.042 13.8 1.9 4 7.3 0.0 3.3 2 1 1 3 3 3 0 Rad17 P-loop domain SRP54 PF00448.22 KXX77268.1 - 0.052 13.2 0.0 3.6 7.2 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 KXX77268.1 - 0.12 12.4 12.1 5.2 7.1 2.7 4.3 3 1 0 3 3 3 0 Dynamin family Arf PF00025.21 KXX77268.1 - 0.14 11.6 0.2 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_27 PF13514.6 KXX77268.1 - 0.43 10.1 10.7 2.3 7.8 0.0 4.1 5 0 0 5 5 3 0 AAA domain ATP_bind_1 PF03029.17 KXX77268.1 - 0.59 9.9 3.0 31 4.2 0.0 3.3 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 KXX77268.1 - 1.5 9.2 8.8 14 6.1 0.2 4.0 4 1 0 4 4 3 0 AAA domain Tubulin PF00091.25 KXX77269.1 - 1e-68 231.4 0.0 2.5e-68 230.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXX77269.1 - 1.1e-42 145.2 0.1 1.6e-42 144.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXX77269.1 - 2.2e-05 24.8 0.0 5.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KXX77269.1 - 0.0016 17.7 0.0 0.024 13.8 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KXX77269.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain bZIP_1 PF00170.21 KXX77270.1 - 1.3e-05 25.2 7.2 2.3e-05 24.4 7.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXX77270.1 - 3.7e-05 23.7 10.0 6.9e-05 22.8 10.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.9 KXX77270.1 - 0.053 12.5 0.5 0.078 12.0 0.5 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.17 KXX77270.1 - 0.1 13.2 3.9 0.21 12.1 3.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 KXX77272.1 - 0.00012 22.1 6.0 0.00019 21.5 6.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXX77272.1 - 0.0076 16.3 7.7 0.012 15.7 7.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper YopE_N PF09020.10 KXX77272.1 - 0.021 15.1 0.1 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 YopE, N terminal PHC2_SAM_assoc PF16616.5 KXX77272.1 - 0.034 15.0 0.4 0.034 15.0 0.4 2.7 2 1 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 TPR_MLP1_2 PF07926.12 KXX77273.1 - 3e-38 130.8 32.3 3e-38 130.8 32.3 18.9 6 5 12 19 19 19 6 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 KXX77273.1 - 0.0009 18.6 8.8 0.0009 18.6 8.8 20.0 5 4 16 21 21 21 2 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 KXX77273.1 - 0.001 18.7 10.9 0.001 18.7 10.9 17.0 3 2 10 17 17 17 3 HAUS augmin-like complex subunit 3 GAS PF13851.6 KXX77273.1 - 0.0032 16.8 5.9 0.0032 16.8 5.9 17.4 7 5 9 17 17 17 5 Growth-arrest specific micro-tubule binding Scm3 PF10384.9 KXX77273.1 - 5.2 6.9 7.6 0.45 10.3 0.1 3.3 3 0 0 3 3 3 0 Centromere protein Scm3 Complex1_51K PF01512.17 KXX77274.1 - 6e-47 159.3 0.0 1e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KXX77274.1 - 9.7e-29 99.3 1.2 1.9e-28 98.4 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KXX77274.1 - 3.4e-09 36.4 0.0 8.9e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 KXX77274.1 - 0.28 11.2 1.0 0.61 10.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Flavoprotein PF02441.19 KXX77275.1 - 1.9e-20 73.2 0.0 3.2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Hexapep PF00132.24 KXX77276.1 - 6e-07 28.9 1.8 1.1e-05 24.9 1.9 2.4 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXX77276.1 - 0.23 11.2 3.0 0.6 9.9 2.3 2.0 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Podoplanin PF05808.11 KXX77277.1 - 0.1 12.7 1.6 0.14 12.3 1.0 1.4 1 1 0 1 1 1 0 Podoplanin Phage_holin_2_4 PF16082.5 KXX77277.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Sec34 PF04136.15 KXX77278.1 - 3.4e-49 166.6 0.1 7.3e-49 165.5 0.1 1.6 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 KXX77278.1 - 0.081 12.7 0.3 0.84 9.4 0.0 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 RCC1 PF00415.18 KXX77279.1 - 4e-29 101.0 6.1 6e-08 33.2 0.0 7.4 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXX77279.1 - 6e-17 61.0 17.7 8.9e-11 41.3 0.0 7.4 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat CLP1_P PF16575.5 KXX77280.1 - 4.7e-13 49.3 0.0 8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 KXX77280.1 - 0.05 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXX77280.1 - 0.22 11.4 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Bromodomain PF00439.25 KXX77281.1 - 1.6e-18 66.5 0.2 1.6e-18 66.5 0.2 1.8 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KXX77281.1 - 4.6e-11 42.6 0.1 1.2e-10 41.2 0.1 1.8 1 1 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.6 KXX77281.1 - 0.12 12.7 18.3 0.3 11.5 10.1 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SHMT PF00464.19 KXX77282.1 - 1.1e-211 702.5 0.0 1.3e-211 702.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KXX77282.1 - 0.00052 19.3 0.0 0.0013 18.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II KKLCAg1 PF15204.6 KXX77282.1 - 0.029 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Cys_Met_Meta_PP PF01053.20 KXX77282.1 - 0.082 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXX77282.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DUF155 PF02582.14 KXX77284.1 - 1.1e-48 165.6 0.0 1.7e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 KXX77284.1 - 0.048 13.3 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Cupin RINT1_TIP1 PF04437.13 KXX77285.1 - 4.4e-183 609.7 0.0 6.6e-183 609.1 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec5 PF15469.6 KXX77285.1 - 0.0075 16.1 1.0 0.054 13.3 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 DHR10 PF18595.1 KXX77285.1 - 0.027 14.5 1.4 0.027 14.5 1.4 3.0 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Orthopox_A5L PF06193.11 KXX77285.1 - 0.041 13.3 1.9 0.11 11.9 1.6 1.8 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like ADIP PF11559.8 KXX77285.1 - 0.054 13.6 2.2 0.21 11.6 2.2 2.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 KXX77285.1 - 0.07 12.9 0.5 0.2 11.4 0.5 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 COG2 PF06148.11 KXX77285.1 - 0.13 12.4 2.2 0.25 11.4 0.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CRISPR_Cse2 PF09485.10 KXX77285.1 - 0.23 12.0 9.4 0.042 14.4 2.5 2.8 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_MLP1_2 PF07926.12 KXX77285.1 - 0.35 10.9 7.0 0.2 11.7 1.2 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mito_carr PF00153.27 KXX77286.1 - 1.4e-58 194.8 1.2 2.5e-21 75.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.20 KXX77287.1 - 6.1e-16 58.4 1.1 9.3e-16 57.8 1.1 1.3 1 0 0 1 1 1 1 RF-1 domain AAA PF00004.29 KXX77289.1 - 2e-45 154.4 0.2 7.7e-45 152.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXX77289.1 - 1.2e-10 41.1 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KXX77289.1 - 2e-08 34.3 0.8 6.6e-08 32.6 0.1 2.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXX77289.1 - 5.4e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXX77289.1 - 2.9e-07 31.0 0.6 3.7e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KXX77289.1 - 3.2e-06 26.5 0.0 6.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXX77289.1 - 2.9e-05 24.4 0.9 0.0088 16.3 0.1 2.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KXX77289.1 - 0.00024 20.9 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXX77289.1 - 0.00046 20.7 0.0 0.0013 19.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KXX77289.1 - 0.00066 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXX77289.1 - 0.00069 19.2 0.1 0.0032 17.0 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KXX77289.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 KXX77289.1 - 0.0012 18.5 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 KXX77289.1 - 0.0013 18.7 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXX77289.1 - 0.0018 18.3 0.2 0.0078 16.3 0.0 2.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KXX77289.1 - 0.0022 18.4 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KXX77289.1 - 0.0029 17.6 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_3 PF07726.11 KXX77289.1 - 0.0055 16.6 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXX77289.1 - 0.0056 16.6 0.5 0.11 12.3 0.0 2.8 2 1 1 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 KXX77289.1 - 0.0071 15.8 0.2 0.016 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXX77289.1 - 0.0075 16.4 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXX77289.1 - 0.008 15.9 0.2 0.03 14.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 KXX77289.1 - 0.012 15.3 1.5 0.013 15.2 0.1 1.9 2 1 0 2 2 1 0 AAA domain TniB PF05621.11 KXX77289.1 - 0.013 14.9 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KXX77289.1 - 0.021 14.6 0.2 0.055 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain Viral_Hsp90 PF03225.14 KXX77289.1 - 0.035 12.6 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AFG1_ATPase PF03969.16 KXX77289.1 - 0.035 13.0 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase ATPase PF06745.13 KXX77289.1 - 0.036 13.4 1.0 0.56 9.5 0.0 2.5 3 0 0 3 3 2 0 KaiC Bac_DnaA PF00308.18 KXX77289.1 - 0.04 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 KXX77289.1 - 0.041 13.7 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXX77289.1 - 0.057 13.3 1.3 0.34 10.8 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KXX77289.1 - 0.067 12.9 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KXX77289.1 - 0.071 12.7 1.3 0.21 11.1 0.3 2.2 2 1 1 3 3 3 0 AAA domain Clathrin_H_link PF13838.6 KXX77289.1 - 0.072 13.0 0.0 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Clathrin-H-link Zeta_toxin PF06414.12 KXX77289.1 - 0.083 12.2 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SPACA9 PF15120.6 KXX77289.1 - 0.12 12.2 0.9 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 AAA_19 PF13245.6 KXX77289.1 - 0.12 12.7 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXX77289.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KXX77289.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KXX77289.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CRAL_TRIO PF00650.20 KXX77290.1 - 1.9e-35 121.9 0.0 3.1e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXX77290.1 - 3.8e-07 30.2 0.2 1.2e-06 28.6 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXX77290.1 - 0.0014 18.8 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.12 KXX77291.1 - 7.8e-10 39.2 2.6 7.8e-10 39.2 2.6 2.1 2 1 1 3 3 3 1 Kinetochore protein Mis14 like kleA_kleC PF17383.2 KXX77291.1 - 0.52 10.7 4.6 3.9 7.9 1.1 2.9 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A VanZ PF04892.12 KXX77292.1 - 2.1e-09 38.1 2.3 2.8e-09 37.7 2.3 1.2 1 0 0 1 1 1 1 VanZ like family Asp-Al_Ex PF06826.12 KXX77292.1 - 0.019 14.8 0.7 0.027 14.3 0.7 1.3 1 0 0 1 1 1 0 Predicted Permease Membrane Region ABC_membrane_3 PF13748.6 KXX77292.1 - 0.19 10.9 0.8 0.26 10.5 0.8 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region RseC_MucC PF04246.12 KXX77292.1 - 0.7 9.9 1.9 22 5.0 1.1 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ferric_reduct PF01794.19 KXX77293.1 - 2.6e-20 72.8 8.1 8.5e-20 71.1 8.1 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXX77293.1 - 1.2e-17 64.4 0.0 1.8e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KXX77293.1 - 2.1e-06 28.4 0.1 0.00061 20.4 0.1 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KXX77293.1 - 2.9e-06 27.3 0.0 1.3e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain Y_phosphatase PF00102.27 KXX77294.1 - 2.3e-46 158.3 0.0 5.5e-37 127.6 0.0 3.0 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXX77294.1 - 0.0023 18.1 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 KXX77294.1 - 0.0043 16.9 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXX77294.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Folliculin PF11704.8 KXX77295.1 - 7.6e-63 211.8 0.0 3.3e-62 209.6 0.0 2.0 3 0 0 3 3 3 1 Vesicle coat protein involved in Golgi to plasma membrane transport Ribonuc_L-PSP PF01042.21 KXX77296.1 - 7.1e-40 135.8 0.0 8.1e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP LETM1 PF07766.13 KXX77297.1 - 3.3e-11 43.0 0.0 2.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 LETM1-like protein HemY_N PF07219.13 KXX77297.1 - 0.036 14.3 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 HemY protein N-terminus RRM_1 PF00076.22 KXX77298.1 - 8.4e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXX77298.1 - 0.0091 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GNAT_acetyltr_2 PF13718.6 KXX77299.1 - 3.4e-97 324.3 0.0 5.9e-97 323.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KXX77299.1 - 9.4e-94 313.5 0.0 1.6e-93 312.8 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KXX77299.1 - 2.8e-64 216.2 0.0 1e-63 214.4 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KXX77299.1 - 6.1e-34 115.8 0.0 1.5e-33 114.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KXX77299.1 - 0.00013 21.8 0.2 0.059 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXX77299.1 - 0.00089 19.5 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Acetyltransf_1 PF00583.25 KXX77299.1 - 0.16 12.3 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Pkinase PF00069.25 KXX77300.1 - 2.9e-72 243.2 0.0 3.5e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77300.1 - 3.3e-29 101.9 0.0 4.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX77300.1 - 6.6e-07 28.9 0.0 9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXX77300.1 - 0.00012 21.0 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXX77300.1 - 0.00061 19.8 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXX77300.1 - 0.00079 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAP2_3 PF14378.6 KXX77301.1 - 1.6e-25 89.9 12.7 3.6e-25 88.8 12.7 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KXX77301.1 - 6.2e-09 35.7 6.3 6.2e-09 35.7 6.3 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KXX77301.1 - 2.3 8.8 6.5 1.3 9.6 2.1 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RNA_polI_A34 PF08208.11 KXX77302.1 - 8.1e-39 133.8 2.1 8.1e-39 133.8 2.1 6.0 2 2 3 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 DAO PF01266.24 KXX77303.1 - 1.6e-69 235.2 0.9 1.9e-69 234.9 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX77303.1 - 4e-08 32.8 0.2 0.0042 16.4 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX77303.1 - 9.4e-08 32.5 0.0 0.0042 17.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX77303.1 - 3.4e-05 24.0 0.3 8e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KXX77303.1 - 0.00037 19.4 0.4 0.027 13.3 0.1 2.1 2 0 0 2 2 2 2 MCRA family GMC_oxred_N PF00732.19 KXX77303.1 - 0.00055 19.4 0.1 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX77303.1 - 0.0006 19.0 0.7 0.65 9.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 KXX77303.1 - 0.0014 18.0 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KXX77303.1 - 0.0018 17.2 0.9 0.052 12.4 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KXX77303.1 - 0.016 14.4 0.2 0.092 12.0 0.1 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KXX77303.1 - 0.13 12.2 0.1 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GSHPx PF00255.19 KXX77304.1 - 4.3e-41 138.9 0.1 5.4e-41 138.5 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXX77304.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KXX77304.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 Redoxin DUF4174 PF13778.6 KXX77304.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) GFO_IDH_MocA PF01408.22 KXX77305.1 - 8.7e-10 39.5 0.2 2.1e-09 38.3 0.2 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXX77305.1 - 0.07 13.8 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 KXX77305.1 - 0.078 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain DHDPS PF00701.22 KXX77306.1 - 3.5e-34 117.8 0.0 4.4e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family LPD26 PF18842.1 KXX77306.1 - 0.13 12.2 0.7 0.65 10.0 0.2 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 Lipase_GDSL_2 PF13472.6 KXX77307.1 - 8.5e-19 68.6 0.2 1.3e-18 68.1 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX77307.1 - 2.4e-10 40.7 0.0 4.4e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PFL-like PF02901.15 KXX77307.1 - 0.083 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like MFS_1 PF07690.16 KXX77309.1 - 2.1e-42 145.3 45.1 3.5e-42 144.6 45.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX77309.1 - 1.1e-17 64.1 4.2 1.1e-17 64.1 4.2 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXX77309.1 - 0.00071 18.5 13.1 0.00071 18.5 13.1 2.6 3 0 0 3 3 3 2 MFS_1 like family DUF1422 PF07226.11 KXX77309.1 - 3.6 7.6 7.5 13 5.9 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) Ank_4 PF13637.6 KXX77310.1 - 3.5e-32 110.3 4.8 6.5e-14 52.1 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX77310.1 - 1.4e-29 102.5 0.3 1.7e-13 50.9 0.2 3.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX77310.1 - 2.4e-23 81.5 1.9 6.2e-06 26.4 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXX77310.1 - 3.2e-19 68.7 2.0 1.8e-07 31.3 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77310.1 - 2.7e-18 64.2 1.8 0.055 14.0 0.0 7.2 7 0 0 7 7 6 4 Ankyrin repeat NACHT PF05729.12 KXX77310.1 - 2.2e-10 40.7 0.1 5.6e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX77310.1 - 3.7e-05 24.2 2.2 0.00013 22.4 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain ApoC-I PF04691.12 KXX77310.1 - 0.0012 18.7 0.1 0.0041 17.0 0.0 1.9 1 1 1 2 2 2 1 Apolipoprotein C-I (ApoC-1) Helo_like_N PF17111.5 KXX77310.1 - 0.0013 18.2 1.4 0.0044 16.4 0.1 2.5 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KXX77310.1 - 0.0025 17.0 0.1 0.017 14.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain SesA PF17107.5 KXX77310.1 - 0.0032 17.7 2.5 0.01 16.0 0.8 2.7 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KXX77310.1 - 0.006 16.9 0.0 0.15 12.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF2383 PF09537.10 KXX77310.1 - 0.04 14.2 0.0 7.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Stork_head PF10264.9 KXX77310.1 - 0.16 12.2 0.5 0.97 9.6 0.1 2.5 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Syntaxin_2 PF14523.6 KXX77310.1 - 0.72 10.3 6.2 1.4 9.3 1.5 3.2 3 1 0 3 3 3 0 Syntaxin-like protein VKOR PF07884.14 KXX77311.1 - 0.09 13.0 5.6 0.12 12.6 5.6 1.2 1 0 0 1 1 1 0 Vitamin K epoxide reductase family DUF2484 PF10658.9 KXX77311.1 - 0.62 10.4 4.3 5.9 7.3 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2484) Git3 PF11710.8 KXX77312.1 - 0.021 14.6 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TIMELESS PF04821.14 KXX77313.1 - 4.5e-86 288.5 0.0 1.1e-85 287.3 0.0 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KXX77313.1 - 1.5e-36 126.7 8.5 1.5e-36 126.7 8.5 5.3 5 2 0 5 5 5 1 Timeless protein C terminal region 3HCDH_N PF02737.18 KXX77314.1 - 6.9e-54 182.5 0.3 9.7e-54 182.0 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXX77314.1 - 5.1e-33 113.6 0.0 1e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KXX77314.1 - 3.1e-05 24.2 0.2 6.4e-05 23.2 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KXX77314.1 - 0.0019 18.4 0.1 0.0051 17.0 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KXX77314.1 - 0.0083 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX77314.1 - 0.0091 15.6 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KXX77314.1 - 0.013 14.8 0.3 0.057 12.8 0.1 1.9 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXX77314.1 - 0.053 14.1 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXX77314.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KXX77314.1 - 0.18 12.0 0.2 0.49 10.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Homeodomain PF00046.29 KXX77315.1 - 7.8e-18 64.1 3.0 1.5e-17 63.2 3.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXX77315.1 - 0.0052 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HLH PF00010.26 KXX77316.1 - 5.9e-12 45.4 0.8 5.9e-12 45.4 0.8 3.0 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 KXX77316.1 - 0.0033 16.5 1.5 0.0047 16.0 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) MnmE_helical PF12631.7 KXX77316.1 - 0.0058 16.8 1.8 0.01 16.0 1.8 1.3 1 0 0 1 1 1 1 MnmE helical domain SlyX PF04102.12 KXX77316.1 - 0.01 16.5 6.3 0.021 15.4 1.2 2.9 1 1 0 2 2 2 0 SlyX Phage_GPO PF05929.11 KXX77316.1 - 0.011 15.4 1.2 0.018 14.7 1.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Taxilin PF09728.9 KXX77316.1 - 0.014 14.6 5.6 0.02 14.1 5.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Fib_alpha PF08702.10 KXX77316.1 - 0.027 14.6 6.3 0.064 13.4 5.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KXX77316.1 - 0.037 14.3 2.0 0.037 14.3 2.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) HeLo PF14479.6 KXX77316.1 - 0.039 13.8 1.8 0.068 13.0 1.8 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF641 PF04859.12 KXX77316.1 - 0.076 13.3 5.3 0.15 12.4 5.0 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 KXX77316.1 - 0.11 12.6 4.6 0.06 13.4 2.2 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.16 KXX77316.1 - 0.14 12.3 5.9 0.48 10.7 5.9 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein DUF745 PF05335.13 KXX77316.1 - 0.17 11.6 2.3 0.32 10.7 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KXX77316.1 - 0.17 11.9 0.8 0.28 11.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MetOD2 PF18548.1 KXX77316.1 - 0.21 11.7 1.3 0.47 10.6 1.3 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 DivIC PF04977.15 KXX77316.1 - 0.21 11.3 0.1 0.21 11.3 0.1 1.6 2 0 0 2 2 1 0 Septum formation initiator Golgin_A5 PF09787.9 KXX77316.1 - 0.26 10.7 9.3 0.41 10.1 9.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 YabA PF06156.13 KXX77316.1 - 0.3 11.7 1.6 0.56 10.9 0.6 1.8 1 1 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 KXX77316.1 - 0.64 10.1 7.3 0.73 9.9 6.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KXX77316.1 - 1.1 9.0 5.4 1.9 8.3 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 KXX77316.1 - 1.2 9.2 8.3 2.4 8.2 8.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 KXX77316.1 - 1.4 8.9 5.3 0.34 10.9 1.5 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 KXX77316.1 - 2.1 7.7 6.2 3.3 7.0 6.2 1.2 1 0 0 1 1 1 0 FAM76 protein Fungal_trans_2 PF11951.8 KXX77317.1 - 4.9e-83 279.1 0.0 6e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX77317.1 - 2.1e-07 31.0 5.2 3.5e-07 30.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.17 KXX77318.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXX77318.1 - 0.00013 22.3 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KXX77318.1 - 0.0002 21.8 0.0 0.0038 17.7 0.0 2.8 2 1 0 2 2 2 1 PH domain ORMDL PF04061.14 KXX77319.1 - 8.9e-59 197.2 3.1 1e-58 196.9 3.1 1.0 1 0 0 1 1 1 1 ORMDL family DHFR_2 PF06442.11 KXX77320.1 - 0.041 13.7 0.5 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 R67 dihydrofolate reductase DUF202 PF02656.15 KXX77321.1 - 1.5e-21 76.6 1.8 1.5e-21 76.6 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Aldo_ket_red PF00248.21 KXX77322.1 - 2.7e-54 184.4 0.0 3.4e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SHR3_chaperone PF08229.11 KXX77323.1 - 2.4e-72 241.9 0.0 2.7e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2157 PF09925.9 KXX77323.1 - 0.0029 17.4 1.0 2.8 7.7 0.6 3.1 2 1 1 3 3 3 2 Predicted membrane protein (DUF2157) Ni_hydr_CYTB PF01292.20 KXX77323.1 - 0.041 13.5 1.1 0.072 12.7 0.3 1.8 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 MGC-24 PF05283.11 KXX77324.1 - 0.0012 19.3 0.9 0.0028 18.1 0.9 1.6 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KXX77324.1 - 0.004 17.1 0.1 0.0064 16.4 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family Insulin_TMD PF17870.1 KXX77324.1 - 0.022 14.8 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 KXX77324.1 - 0.079 13.9 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CDC45 PF02724.14 KXX77325.1 - 0.034 12.5 5.7 0.044 12.1 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein HATPase_c PF02518.26 KXX77326.1 - 1.1e-28 100.0 0.2 2.1e-20 73.3 0.0 2.9 1 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXX77326.1 - 1.2e-27 96.2 0.1 2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXX77326.1 - 7.4e-15 54.7 0.0 1.9e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KXX77326.1 - 0.0074 16.6 0.0 0.051 14.0 0.0 2.4 2 0 0 2 2 2 1 HAMP domain NBP1 PF08537.10 KXX77326.1 - 0.13 11.7 0.4 0.27 10.6 0.4 1.5 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Aldo_ket_red PF00248.21 KXX77327.1 - 4.8e-08 32.6 0.0 6.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 KXX77328.1 - 6.7e-07 28.9 0.0 8.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXX77328.1 - 9.4e-07 29.0 1.1 0.013 15.5 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXX77328.1 - 1.1e-06 28.2 0.0 9.3e-05 21.9 0.0 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXX77328.1 - 0.0059 15.9 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXX77328.1 - 0.0079 15.8 0.0 2.6 7.6 0.0 2.6 3 0 0 3 3 3 2 RIO1 family Pkinase_fungal PF17667.1 KXX77328.1 - 0.023 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CMD PF02627.20 KXX77330.1 - 2.9e-08 33.7 0.5 1e-07 31.9 0.1 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Maf1 PF09174.10 KXX77331.1 - 1.4e-64 217.5 0.1 1.9e-64 217.0 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 KXX77332.1 - 1.4e-51 174.2 1.5 1.7e-51 173.9 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KXX77332.1 - 0.017 15.8 0.1 0.03 15.1 0.1 1.5 1 0 0 1 1 1 0 Pullulanase N1-terminal domain YchF-GTPase_C PF06071.13 KXX77333.1 - 4.4e-35 119.7 0.2 4.4e-35 119.7 0.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXX77333.1 - 2.2e-16 60.0 0.0 5.1e-16 58.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX77333.1 - 0.0005 19.6 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KXX77333.1 - 0.00097 19.1 0.1 0.0026 17.8 0.1 1.7 1 0 0 1 1 1 1 TGS domain AAA_23 PF13476.6 KXX77333.1 - 0.037 14.5 0.7 6.2 7.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KXX77333.1 - 0.091 13.3 0.4 12 6.5 0.0 3.2 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KXX77333.1 - 1.2 9.7 3.4 5.7 7.5 0.2 2.7 2 1 0 2 2 2 0 ABC transporter VPS9 PF02204.18 KXX77334.1 - 4.4e-20 71.8 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KXX77334.1 - 6.4e-18 64.6 0.8 5.5e-13 48.9 0.0 5.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX77334.1 - 5.2e-13 49.4 0.0 0.00028 21.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77334.1 - 2.5e-08 34.3 0.1 0.13 12.9 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77334.1 - 7e-08 32.2 0.0 0.4 11.4 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 KXX77334.1 - 0.002 18.5 0.0 9.3 6.9 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat PX PF00787.24 KXX77334.1 - 0.006 16.6 0.1 0.063 13.3 0.0 2.5 2 0 0 2 2 2 1 PX domain PKS_DE PF18369.1 KXX77334.1 - 0.22 12.1 0.1 0.22 12.1 0.1 3.9 4 0 0 4 4 4 0 Polyketide synthase dimerisation element domain GvpL_GvpF PF06386.11 KXX77334.1 - 1.8 8.4 4.8 1.9 8.4 1.7 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF 3Beta_HSD PF01073.19 KXX77335.1 - 3e-20 72.4 0.0 8.2e-20 70.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXX77335.1 - 2.1e-10 40.5 0.0 4.1e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXX77335.1 - 1.9e-08 33.8 0.0 2.1e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KXX77335.1 - 1.6e-05 24.9 0.0 3.9e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXX77335.1 - 0.0011 18.9 0.0 0.0031 17.5 0.0 1.7 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXX77335.1 - 0.0042 16.5 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXX77335.1 - 0.078 13.2 0.0 0.49 10.7 0.0 2.1 1 1 1 2 2 2 0 TrkA-N domain DUF4750 PF15938.5 KXX77335.1 - 0.12 12.0 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) Sacchrp_dh_NADP PF03435.18 KXX77335.1 - 0.14 12.4 0.0 0.7 10.2 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Peptidase_C97 PF05903.14 KXX77336.1 - 8.9e-37 126.2 0.0 1.1e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXX77336.1 - 0.00072 19.9 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase AAA_11 PF13086.6 KXX77337.1 - 9e-59 199.4 0.2 2.1e-58 198.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KXX77337.1 - 3.3e-55 186.8 0.0 7.3e-55 185.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXX77337.1 - 8.2e-11 42.0 0.0 1.6e-09 37.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX77337.1 - 1.5e-07 31.8 0.0 8.9e-07 29.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KXX77337.1 - 8.3e-07 28.6 0.1 4e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KXX77337.1 - 2e-06 27.7 0.0 0.74 9.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXX77337.1 - 3.2e-05 23.6 0.0 0.00015 21.4 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KXX77337.1 - 7.8e-05 22.7 0.0 0.00044 20.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXX77337.1 - 0.00089 19.5 0.1 0.0087 16.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX77337.1 - 0.0012 19.3 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KXX77337.1 - 0.0028 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 KXX77337.1 - 0.0028 17.5 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_25 PF13481.6 KXX77337.1 - 0.0032 17.1 0.2 0.22 11.0 0.0 3.1 2 1 1 3 3 3 1 AAA domain Flavi_DEAD PF07652.14 KXX77337.1 - 0.0036 17.3 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain DEAD PF00270.29 KXX77337.1 - 0.0046 16.7 0.0 0.058 13.2 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KXX77337.1 - 0.005 16.3 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 KXX77337.1 - 0.005 17.3 0.0 0.029 14.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX77337.1 - 0.0058 16.8 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KXX77337.1 - 0.029 14.2 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 KXX77337.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 KXX77337.1 - 0.041 12.8 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 KXX77337.1 - 0.055 13.2 0.0 0.25 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain 4HB_MCP_1 PF12729.7 KXX77337.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction UvrD_C PF13361.6 KXX77337.1 - 0.06 12.7 0.0 2.7 7.3 0.0 2.6 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 KXX77337.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein betaPIX_CC PF16523.5 KXX77338.1 - 0.0035 17.1 0.3 0.0079 16.0 0.3 1.5 1 0 0 1 1 1 1 betaPIX coiled coil Lzipper-MIP1 PF14389.6 KXX77338.1 - 0.032 14.5 0.4 0.089 13.1 0.4 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 KXX77338.1 - 0.18 11.6 2.3 0.44 10.4 2.3 1.6 1 0 0 1 1 1 0 Septum formation initiator NOG1_N PF17835.1 KXX77339.1 - 3.2e-35 121.5 8.4 4.1e-35 121.1 2.3 3.1 2 1 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KXX77339.1 - 3e-27 94.4 2.0 6.6e-27 93.3 2.0 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KXX77339.1 - 4.1e-26 90.5 0.2 7.9e-26 89.6 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KXX77339.1 - 1.3e-10 41.4 0.0 2.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Acetyltransf_10 PF13673.7 KXX77339.1 - 7.6e-08 32.4 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FeoB_N PF02421.18 KXX77339.1 - 4.7e-06 26.2 0.0 8.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Acetyltransf_1 PF00583.25 KXX77339.1 - 1.9e-05 24.8 0.0 4.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX77339.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_16 PF13191.6 KXX77339.1 - 0.04 14.3 0.0 0.27 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Pribosyltran PF00156.27 KXX77340.1 - 8.2e-14 51.4 0.3 1.2e-13 50.8 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans_2 PF11951.8 KXX77341.1 - 8.9e-17 61.0 0.3 6.5e-14 51.5 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX77341.1 - 5.7e-09 36.0 10.7 9.4e-09 35.3 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX77341.1 - 0.0009 18.3 0.2 0.0024 16.9 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.24 KXX77341.1 - 0.31 11.2 2.4 7.8 6.7 1.7 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Proteasome PF00227.26 KXX77342.1 - 3.5e-57 193.0 0.3 4.4e-57 192.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXX77342.1 - 1.5e-12 46.9 0.0 3.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FA_desaturase PF00487.24 KXX77343.1 - 7.3e-18 65.3 11.0 7.3e-18 65.3 11.0 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXX77343.1 - 1.5e-17 63.5 0.0 2.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain APH PF01636.23 KXX77344.1 - 0.00013 22.0 0.2 0.023 14.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family HAD_2 PF13419.6 KXX77345.1 - 5.2e-11 42.9 0.0 7.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX77345.1 - 3.6e-10 40.5 0.0 6.3e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXX77345.1 - 6.5e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXX77345.1 - 0.043 14.2 0.0 0.058 13.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KXX77345.1 - 0.047 13.5 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase SelP_N PF04592.14 KXX77346.1 - 1.5 8.2 16.5 3.6 6.9 16.5 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2034 PF10356.9 KXX77347.1 - 8.7e-23 80.7 0.0 2e-20 73.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Med21 PF11221.8 KXX77348.1 - 3.1e-44 150.7 2.9 3.5e-44 150.6 2.9 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.6 KXX77348.1 - 0.0047 16.3 1.8 2.2 7.6 0.2 2.7 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.13 KXX77348.1 - 0.01 15.9 0.9 0.01 15.9 0.9 2.4 3 1 1 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.8 KXX77348.1 - 0.1 12.6 2.6 0.21 11.6 2.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Lon_C PF05362.13 KXX77349.1 - 3.1e-64 216.3 0.0 6.7e-64 215.2 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXX77349.1 - 5.2e-33 114.7 0.1 2.8e-32 112.3 0.0 2.2 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXX77349.1 - 4.8e-22 78.8 0.0 1.2e-21 77.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KXX77349.1 - 9e-09 35.2 0.0 2.8e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KXX77349.1 - 4e-07 30.1 0.0 8.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXX77349.1 - 2.6e-06 27.6 0.0 6.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXX77349.1 - 4.9e-05 23.6 0.0 0.00051 20.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KXX77349.1 - 5.6e-05 22.2 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KXX77349.1 - 0.00013 21.7 0.3 0.00079 19.2 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX77349.1 - 0.00044 20.7 0.7 0.002 18.5 0.1 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 KXX77349.1 - 0.0043 17.6 0.2 0.068 13.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KXX77349.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXX77349.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXX77349.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KXX77349.1 - 0.054 13.9 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KXX77349.1 - 0.054 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KXX77349.1 - 0.068 12.7 0.3 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KXX77349.1 - 0.11 12.3 0.2 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 NTPase F-box-like_2 PF13013.6 KXX77349.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Cytidylate_kin PF02224.18 KXX77349.1 - 0.46 10.2 3.0 9 6.0 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase ABC_tran PF00005.27 KXX77349.1 - 0.85 10.1 3.5 1 9.9 0.1 2.7 3 0 0 3 3 3 0 ABC transporter MCPVI PF02993.14 KXX77349.1 - 3.4 7.5 5.8 24 4.7 1.0 2.5 2 0 0 2 2 2 0 Minor capsid protein VI Presenilin PF01080.17 KXX77350.1 - 1.4 7.6 2.4 1.8 7.3 2.4 1.2 1 0 0 1 1 1 0 Presenilin Apis_Csd PF11671.8 KXX77350.1 - 4.4 7.3 6.8 7.1 6.6 6.8 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein DUF3915 PF13054.6 KXX77350.1 - 7.5 6.6 6.2 12 5.9 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Pkinase PF00069.25 KXX77352.1 - 1.1e-13 51.2 0.0 9.2e-13 48.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77352.1 - 7.4e-13 48.4 0.0 1.1e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Asp_protease PF09668.10 KXX77353.1 - 1.5e-58 195.9 0.1 2.2e-58 195.5 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXX77353.1 - 6.7e-23 81.1 0.0 1.3e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXX77353.1 - 1.6e-10 41.5 0.0 3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 KXX77353.1 - 1.3e-08 34.6 0.1 3.3e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 KXX77353.1 - 6.3e-07 29.0 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.6 KXX77353.1 - 6.2e-05 22.7 0.1 0.00011 21.9 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 KXX77353.1 - 0.00076 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.8 KXX77353.1 - 0.0014 19.1 0.1 0.0025 18.2 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 RVP PF00077.20 KXX77353.1 - 0.0014 18.9 0.0 0.0037 17.6 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Bep_C_terminal PF17841.1 KXX77353.1 - 0.085 13.1 0.4 7.9 6.8 0.0 2.8 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) YukD PF08817.10 KXX77353.1 - 0.13 12.9 0.2 0.45 11.2 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 KXX77353.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain NAD_binding_7 PF13241.6 KXX77353.1 - 0.18 12.2 0.0 6.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Methyltransf_23 PF13489.6 KXX77354.1 - 2.1e-13 50.4 0.0 3.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77354.1 - 1.5e-12 48.0 0.0 4.2e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77354.1 - 7.8e-12 45.7 0.0 2.8e-11 43.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX77354.1 - 2.4e-08 33.9 0.0 1.6e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77354.1 - 1.4e-07 32.2 0.0 2.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXX77354.1 - 9.7e-05 21.9 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KXX77354.1 - 0.0025 17.2 0.0 0.0072 15.7 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 KXX77354.1 - 0.049 12.2 0.0 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KXX77354.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase SNF2_N PF00176.23 KXX77355.1 - 8.3e-71 238.5 0.1 1.2e-70 238.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX77355.1 - 1.1e-11 45.0 0.0 4.1e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX77355.1 - 1.5e-05 24.8 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXX77355.1 - 0.0016 18.4 0.0 0.0063 16.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HIRAN PF08797.11 KXX77355.1 - 0.0035 17.2 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain WW PF00397.26 KXX77355.1 - 0.0071 16.4 0.5 0.016 15.3 0.5 1.6 1 0 0 1 1 1 1 WW domain zf-RING_5 PF14634.6 KXX77355.1 - 0.12 12.3 8.7 0.24 11.4 8.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXX77355.1 - 0.74 10.0 5.5 1.7 8.9 5.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KXX77355.1 - 1.9 8.4 8.5 3.8 7.5 8.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YqeY PF09424.10 KXX77356.1 - 1.5e-16 60.8 8.3 1.5e-16 60.8 8.3 1.8 2 0 0 2 2 2 1 Yqey-like protein GP24_25 PF17388.2 KXX77356.1 - 0.15 12.1 7.0 2.8 7.9 2.3 2.7 2 1 1 3 3 3 0 Tail assembly gene products 24 & 25 GCP_N_terminal PF17681.1 KXX77357.1 - 1.6e-63 215.1 0.1 4.4e-63 213.8 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXX77357.1 - 2e-61 208.1 1.9 2e-61 208.1 1.9 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal KH_1 PF00013.29 KXX77358.1 - 3.9e-30 103.5 1.8 1e-06 28.4 0.0 6.6 6 0 0 6 6 6 6 KH domain GDI PF00996.18 KXX77359.1 - 3.2e-18 65.5 0.0 3.5e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Methyltransf_8 PF05148.15 KXX77360.1 - 3.5e-56 190.5 0.0 6.9e-55 186.3 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KXX77360.1 - 4.3e-07 30.5 0.0 1.2e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77360.1 - 6.7e-05 23.5 0.0 0.00034 21.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX77360.1 - 0.0073 16.1 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KXX77360.1 - 0.026 14.1 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KXX77360.1 - 0.54 10.2 0.0 0.54 10.2 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain 7tm_1 PF00001.21 KXX77361.1 - 7.2e-13 48.5 0.9 8.9e-13 48.2 0.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 KXX77361.1 - 8.5e-13 48.2 4.0 8.5e-13 48.2 4.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KXX77361.1 - 2.4e-12 46.6 8.4 2.4e-12 46.6 8.4 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KXX77361.1 - 2.1e-07 30.9 10.1 2.1e-07 30.9 10.1 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KXX77361.1 - 8.2e-06 25.4 2.6 1.4e-05 24.6 2.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx STE3 PF02076.15 KXX77361.1 - 0.00019 20.8 6.3 0.00019 20.8 6.3 2.0 2 0 0 2 2 2 1 Pheromone A receptor Peptidase_C12 PF01088.21 KXX77362.1 - 3.8e-70 235.9 0.0 4.8e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXX77362.1 - 2.7e-10 40.0 0.1 5.8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Ribosomal_L22 PF00237.19 KXX77363.1 - 5.1e-41 139.1 0.0 7.4e-41 138.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 KXX77363.1 - 0.01 16.2 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 0 Lamin Tail Domain Fibrillarin PF01269.17 KXX77364.1 - 1.1e-103 345.2 0.0 1.4e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KXX77364.1 - 3.9e-06 26.7 0.0 5.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KXX77364.1 - 0.0047 16.7 0.1 0.007 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KXX77364.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF4558 PF15104.6 KXX77365.1 - 0.5 10.5 6.2 0.12 12.5 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4558) zf-rbx1 PF12678.7 KXX77366.1 - 3.8e-10 39.9 4.9 6.8e-10 39.1 4.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXX77366.1 - 1.7e-09 37.8 5.3 3.3e-09 36.9 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX77366.1 - 7.6e-06 25.7 3.5 1.3e-05 24.9 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX77366.1 - 5.9e-05 23.0 1.8 0.00012 22.0 1.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXX77366.1 - 6.8e-05 22.7 6.8 0.0012 18.7 7.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX77366.1 - 8.4e-05 22.4 2.6 0.00028 20.8 2.9 1.8 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXX77366.1 - 0.00029 20.6 1.6 0.00067 19.5 1.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXX77366.1 - 0.00038 20.5 0.5 0.00078 19.4 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXX77366.1 - 0.00051 19.6 0.6 0.00051 19.6 0.6 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KXX77366.1 - 0.0016 18.2 6.2 0.0038 17.0 6.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXX77366.1 - 0.063 13.0 2.1 0.57 10.0 2.1 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-FPG_IleRS PF06827.14 KXX77366.1 - 0.11 12.4 0.9 0.26 11.2 0.9 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-RING_4 PF14570.6 KXX77366.1 - 0.85 9.5 3.4 2.2 8.2 3.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXX77366.1 - 2.4 8.4 5.0 2.4 8.4 2.8 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain PS_Dcarbxylase PF02666.15 KXX77367.1 - 1.4e-78 263.0 0.0 1.6e-76 256.3 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 KXX77367.1 - 0.048 13.3 0.0 0.18 11.5 0.0 2.0 1 0 0 1 1 1 0 MNLL subunit Biotin_lipoyl_2 PF13533.6 KXX77367.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Biotin-lipoyl like ubiquitin PF00240.23 KXX77368.1 - 3.1e-06 26.9 0.0 7.7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KXX77368.1 - 6.2e-06 26.7 0.4 6.2e-06 26.7 0.4 2.9 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain PepSY_TM PF03929.16 KXX77368.1 - 0.0021 17.8 0.4 0.0021 17.8 0.4 4.0 3 2 0 5 5 5 1 PepSY-associated TM region DUF4834 PF16118.5 KXX77368.1 - 0.0027 18.7 0.3 0.0027 18.7 0.3 3.6 4 0 0 4 4 3 1 Domain of unknown function (DUF4834) Pex14_N PF04695.13 KXX77368.1 - 0.0073 17.0 0.0 0.0073 17.0 0.0 5.2 4 1 1 5 5 5 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Trypan_PARP PF05887.11 KXX77368.1 - 0.0079 16.2 1.6 0.0079 16.2 1.6 2.5 3 0 0 3 3 2 1 Procyclic acidic repetitive protein (PARP) TrbL PF04610.14 KXX77368.1 - 0.068 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Rad60-SLD PF11976.8 KXX77368.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF719 PF05334.13 KXX77368.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF719) DUF2828 PF11443.8 KXX77368.1 - 1.1 7.2 4.0 1.9 6.5 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EIIBC-GUT_N PF03612.14 KXX77368.1 - 4 7.1 9.7 7.5 6.3 0.9 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FAD_binding_1 PF00667.20 KXX77369.1 - 3.2e-45 154.4 0.0 4.5e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXX77369.1 - 6.8e-10 39.6 0.0 3.9e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.24 KXX77370.1 - 1.8e-17 63.9 0.0 2.3e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family adh_short_C2 PF13561.6 KXX77371.1 - 2.3e-45 155.0 0.9 3.1e-45 154.5 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX77371.1 - 2.2e-42 144.7 0.3 3.2e-42 144.2 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXX77371.1 - 3.9e-12 46.4 0.5 6.1e-12 45.8 0.5 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KXX77371.1 - 0.13 12.0 1.1 1.6 8.5 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase N2227 PF07942.12 KXX77372.1 - 5.9e-99 330.7 0.0 7.2e-99 330.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KXX77372.1 - 9.1e-07 28.8 0.0 1.6e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77372.1 - 0.001 19.8 0.0 0.0075 17.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77372.1 - 0.0017 19.0 0.0 0.0098 16.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF1569 PF07606.11 KXX77372.1 - 0.039 13.9 0.2 4.2 7.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1569) DUF5495 PF17599.2 KXX77372.1 - 0.092 13.0 0.1 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5495) Methyltransf_25 PF13649.6 KXX77372.1 - 0.13 13.0 0.0 0.81 10.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXX77372.1 - 0.15 11.8 0.0 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 KXX77373.1 - 6e-05 22.8 0.0 9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PemK_toxin PF02452.17 KXX77374.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system zf-C2H2 PF00096.26 KXX77376.1 - 4.8e-05 23.6 18.0 0.32 11.5 0.8 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX77376.1 - 0.078 13.9 19.4 1.4 9.9 0.6 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger zf-TAZ PF02135.16 KXX77376.1 - 0.28 11.7 3.6 0.43 11.1 1.2 2.1 2 0 0 2 2 2 0 TAZ zinc finger TT_ORF2 PF02957.15 KXX77376.1 - 2.3 9.2 6.6 0.3 12.0 2.0 1.9 2 0 0 2 2 2 0 TT viral ORF2 FOXP-CC PF16159.5 KXX77376.1 - 6.6 7.5 6.8 24 5.6 1.2 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain HEAT_EZ PF13513.6 KXX77377.1 - 1.9e-28 98.4 15.7 4.1e-17 62.3 0.0 11.1 11 3 1 12 12 12 2 HEAT-like repeat HEAT PF02985.22 KXX77377.1 - 1.5e-21 74.6 15.6 8.2e-06 25.7 0.0 10.3 12 0 0 12 12 10 5 HEAT repeat HEAT_2 PF13646.6 KXX77377.1 - 2.9e-18 66.0 0.1 2.1e-05 24.8 0.0 7.4 4 3 2 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KXX77377.1 - 9.1e-08 32.3 0.0 0.64 10.0 0.0 4.8 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXX77377.1 - 1.4e-07 32.0 0.0 0.3 11.7 0.0 6.1 5 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KXX77377.1 - 8.7e-07 28.4 7.1 0.06 12.5 0.0 5.4 5 2 1 6 6 6 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KXX77377.1 - 5.2e-06 26.3 4.9 1.3e-05 25.0 0.6 4.0 4 1 0 4 4 4 1 Importin-beta N-terminal domain RIX1 PF08167.12 KXX77377.1 - 0.00014 21.7 0.2 4.8 6.9 0.0 5.6 7 1 0 7 7 7 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 KXX77377.1 - 0.00046 19.8 0.0 5.1 6.6 0.0 5.9 8 1 0 8 8 8 1 CLASP N terminal RTP1_C1 PF10363.9 KXX77377.1 - 0.0013 18.9 0.0 0.097 12.9 0.0 3.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 KXX77377.1 - 0.026 14.4 0.1 1.4 8.9 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) Arm PF00514.23 KXX77377.1 - 0.054 13.6 6.3 0.87 9.7 0.0 5.4 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KXX77377.1 - 0.084 13.2 0.0 15 6.0 0.0 3.7 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain HEAT_PBS PF03130.16 KXX77377.1 - 0.12 13.1 5.4 3.7 8.5 0.0 5.0 5 0 0 5 5 2 0 PBS lyase HEAT-like repeat PAC4 PF16093.5 KXX77378.1 - 1.7e-23 82.6 0.0 2.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Speriolin_N PF15058.6 KXX77378.1 - 0.033 14.3 2.7 0.34 11.0 2.7 2.0 1 1 0 1 1 1 0 Speriolin N terminus Ank_2 PF12796.7 KXX77379.1 - 2.5e-47 159.3 0.0 1.3e-14 54.6 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77379.1 - 7e-40 134.9 0.1 1.6e-09 38.1 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXX77379.1 - 1.4e-28 98.1 0.2 5.9e-06 26.5 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KXX77379.1 - 5.4e-25 84.7 0.0 0.00012 22.2 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXX77379.1 - 1.6e-24 85.6 1.1 2.9e-05 24.2 0.0 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 KXX77379.1 - 0.08 12.9 0.5 13 5.8 0.1 3.5 3 0 0 3 3 3 0 Superinfection immunity protein DUF3734 PF12536.8 KXX77379.1 - 0.15 12.4 0.2 1.4 9.3 0.0 2.6 2 1 1 3 3 3 0 Patatin phospholipase TetR_C_11 PF16859.5 KXX77379.1 - 0.44 10.9 5.4 0.25 11.6 1.7 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HET PF06985.11 KXX77380.1 - 2.1e-05 24.9 0.0 2.3e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zinc_ribbon_10 PF10058.9 KXX77381.1 - 4.9e-19 67.8 0.1 8.1e-19 67.1 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-tcix PF14952.6 KXX77381.1 - 0.17 11.5 2.1 0.32 10.6 0.2 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding CCDC-167 PF15188.6 KXX77381.1 - 0.43 11.0 2.0 3.9 7.9 0.0 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 GRIP PF01465.20 KXX77382.1 - 1.3e-15 57.0 0.3 2.7e-15 56.0 0.3 1.6 1 0 0 1 1 1 1 GRIP domain HOOK PF05622.12 KXX77382.1 - 5.9e-08 31.4 132.8 1.4e-06 26.8 21.2 3.6 2 1 1 3 3 3 2 HOOK protein WEMBL PF05701.11 KXX77382.1 - 1.4e-05 24.0 21.0 1.4e-05 24.0 21.0 5.6 3 1 3 6 6 5 1 Weak chloroplast movement under blue light UPF0242 PF06785.11 KXX77382.1 - 2.6e-05 24.4 138.9 0.0009 19.4 12.2 9.1 2 2 5 7 7 7 3 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 KXX77382.1 - 0.00011 22.8 138.5 0.048 14.1 20.0 8.1 2 1 6 8 8 8 4 Fez1 Spc7 PF08317.11 KXX77382.1 - 0.00012 21.1 151.4 0.098 11.5 17.9 8.0 3 2 5 8 8 8 6 Spc7 kinetochore protein DivIC PF04977.15 KXX77382.1 - 0.0002 21.0 1.6 0.0002 21.0 1.6 14.7 7 3 8 15 15 15 4 Septum formation initiator DUF3584 PF12128.8 KXX77382.1 - 0.00038 18.2 22.1 0.00038 18.2 22.1 4.8 4 1 1 5 5 5 1 Protein of unknown function (DUF3584) APG6_N PF17675.1 KXX77382.1 - 0.00042 20.8 186.1 0.058 13.9 3.2 11.2 4 2 6 10 10 9 3 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KXX77382.1 - 0.00052 20.1 161.6 0.0076 16.3 9.0 9.3 3 2 6 9 9 8 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 KXX77382.1 - 0.0011 18.0 49.2 0.0011 18.0 49.2 5.6 3 2 2 5 5 5 1 Calcium binding and coiled-coil domain (CALCOCO1) like Baculo_PEP_C PF04513.12 KXX77382.1 - 0.0016 18.5 4.6 0.0016 18.5 4.6 7.7 4 3 4 8 8 8 3 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 KXX77382.1 - 0.0018 17.7 147.2 0.25 10.7 14.0 9.1 3 2 5 9 9 9 6 Growth-arrest specific micro-tubule binding Cep57_CLD PF14073.6 KXX77382.1 - 0.0023 18.0 34.6 0.0023 18.0 34.6 8.6 3 3 4 8 8 7 4 Centrosome localisation domain of Cep57 Shugoshin_N PF07558.11 KXX77382.1 - 0.01 15.7 0.4 0.01 15.7 0.4 7.8 11 0 0 11 11 11 0 Shugoshin N-terminal coiled-coil region QueH PF02677.14 KXX77382.1 - 0.073 13.2 0.9 0.62 10.1 0.9 2.6 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH DUF3800 PF12686.7 KXX77382.1 - 0.082 13.5 0.0 21 5.8 0.0 4.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) AAA_13 PF13166.6 KXX77382.1 - 0.085 11.5 107.0 0.012 14.3 19.7 5.6 3 1 2 5 5 5 0 AAA domain Peptidase_M16_M PF16187.5 KXX77385.1 - 3.3e-93 312.0 0.5 5.6e-93 311.3 0.0 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXX77385.1 - 8e-34 117.2 0.2 3.9e-18 66.1 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXX77385.1 - 7.6e-29 100.6 1.4 2.5e-28 98.9 0.1 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) TssN PF17555.2 KXX77386.1 - 0.05 13.0 2.5 0.062 12.7 2.5 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN GFA PF04828.14 KXX77388.1 - 1.5e-15 57.3 8.4 3.3e-07 30.5 0.6 4.2 4 1 0 4 4 4 3 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KXX77388.1 - 0.17 12.1 6.4 16 5.8 4.1 2.9 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Xan_ur_permease PF00860.20 KXX77389.1 - 2.9e-26 92.1 31.1 2.5e-24 85.7 29.1 3.0 2 1 0 2 2 2 2 Permease family Zn_clus PF00172.18 KXX77390.1 - 0.064 13.4 9.1 0.12 12.5 9.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.23 KXX77391.1 - 6.4e-23 80.5 0.0 2e-22 79.0 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXX77391.1 - 3.2e-18 65.8 0.0 1.1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KXX77391.1 - 0.00032 20.8 0.2 0.0077 16.3 0.0 2.5 1 1 1 2 2 2 1 Bd3614-like deaminase Zn_clus PF00172.18 KXX77392.1 - 0.08 13.1 3.5 0.16 12.1 3.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MITF_TFEB_C_3_N PF15951.5 KXX77393.1 - 0.012 16.2 0.0 0.017 15.7 0.0 1.2 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus DUF1656 PF07869.12 KXX77393.1 - 0.032 14.2 0.6 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) BAR PF03114.18 KXX77394.1 - 2.8e-14 53.4 0.0 4.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KXX77394.1 - 2.3e-11 43.4 0.1 3.8e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXX77394.1 - 3e-11 42.7 0.1 5.8e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXX77394.1 - 1.5e-07 31.0 0.1 3.3e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 KXX77394.1 - 0.015 15.8 1.4 0.015 15.8 1.4 2.9 3 0 0 3 3 3 0 Proline rich region of Caskin proteins DUF2439 PF10382.9 KXX77395.1 - 5.9e-27 93.8 0.1 8.8e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) MazE_antitoxin PF04014.18 KXX77395.1 - 0.04 13.9 0.5 0.082 12.9 0.5 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin WD40 PF00400.32 KXX77396.1 - 2.9e-10 40.6 0.6 0.23 12.4 0.0 7.2 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX77396.1 - 3.6e-06 27.2 0.0 0.12 12.6 0.0 4.4 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXX77396.1 - 0.00023 21.0 0.3 0.029 14.3 0.1 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat HgmA PF04209.13 KXX77397.1 - 4e-113 378.3 0.0 4.7e-113 378.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ribosomal_S10 PF00338.22 KXX77400.1 - 5.4e-26 90.7 0.2 6.5e-26 90.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L17 PF01196.19 KXX77400.1 - 0.056 14.4 0.4 0.067 14.1 0.4 1.2 1 0 0 1 1 1 0 Ribosomal protein L17 TauD PF02668.16 KXX77401.1 - 9.5e-42 143.6 0.1 1.3e-41 143.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXX77401.1 - 1.1e-07 32.4 0.0 2.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KXX77401.1 - 0.0053 15.9 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 CsiD Gly_transf_sug PF04488.15 KXX77402.1 - 7.7e-10 39.3 0.0 1.3e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HdeA PF06411.11 KXX77402.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 HdeA/HdeB family Band_7 PF01145.25 KXX77403.1 - 9.4e-15 55.1 0.5 9.4e-15 55.1 0.5 3.5 2 2 0 2 2 2 1 SPFH domain / Band 7 family Zein PF01559.16 KXX77403.1 - 0.18 11.4 2.6 0.39 10.3 2.6 1.4 1 0 0 1 1 1 0 Zein seed storage protein NPH-II PF12011.8 KXX77403.1 - 0.52 10.2 2.4 0.96 9.3 0.7 2.3 2 1 0 2 2 2 0 RNA helicase NPH-II MFS_1 PF07690.16 KXX77404.1 - 9.8e-43 146.4 56.9 2.5e-42 145.1 56.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX77404.1 - 2.8e-13 49.2 23.3 4.3e-13 48.6 23.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX77404.1 - 2.3e-11 43.2 11.2 2.3e-11 43.2 11.2 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter U3_assoc_6 PF08640.11 KXX77406.1 - 3.6e-24 84.6 1.0 8.7e-24 83.4 0.5 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 KXX77406.1 - 0.0041 16.3 0.9 0.039 13.1 0.0 2.5 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KXX77406.1 - 0.0087 16.8 1.4 0.0087 16.8 1.4 4.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXX77406.1 - 0.05 13.7 5.9 0.062 13.4 3.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_72 PF03198.14 KXX77407.1 - 5.4e-70 236.1 0.0 7.1e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Frag1 PF10277.9 KXX77408.1 - 7e-40 136.9 7.9 7e-40 136.9 7.9 2.9 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KXX77408.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 KXX77409.1 - 3.5e-66 223.9 0.0 4.6e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.18 KXX77410.1 - 1.7e-21 76.9 0.7 5.1e-21 75.3 0.7 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mpv17_PMP22 PF04117.12 KXX77410.1 - 0.023 14.9 0.1 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 Mpv17 / PMP22 family ADP_PFK_GK PF04587.15 KXX77410.1 - 0.034 12.7 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Sec7_N PF12783.7 KXX77410.1 - 0.23 11.4 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal OTT_1508_deam PF14441.6 KXX77411.1 - 2.6e-18 65.8 0.0 6.3e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 OTT_1508-like deaminase EVE PF01878.18 KXX77413.1 - 2.4e-49 167.1 0.1 3.5e-49 166.5 0.1 1.3 1 0 0 1 1 1 1 EVE domain 4HBT_3 PF13622.6 KXX77414.1 - 7.8e-37 127.9 0.5 9.1e-37 127.6 0.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXX77414.1 - 0.0097 16.2 0.1 0.11 12.9 0.0 2.5 2 0 0 2 2 2 1 Thioesterase superfamily IRS PF02174.17 KXX77414.1 - 0.14 12.1 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 PTB domain (IRS-1 type) HGWP PF03578.15 KXX77415.1 - 0.018 14.6 0.1 0.018 14.6 0.1 2.2 2 0 0 2 2 2 0 HGWP repeat CUE PF02845.16 KXX77417.1 - 1e-09 37.9 0.0 4.1e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 CUE domain zf-CCCH PF00642.24 KXX77418.1 - 1.7e-07 31.0 4.0 2.9e-07 30.2 4.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXX77418.1 - 7.8e-07 28.8 4.7 1.5e-06 27.9 4.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXX77418.1 - 2e-06 27.7 9.2 3.7e-06 26.8 9.2 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KXX77418.1 - 0.055 14.2 0.9 0.11 13.3 0.9 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KXX77418.1 - 0.13 12.8 3.6 0.35 11.4 3.6 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Sulfate_transp PF00916.20 KXX77419.1 - 3.3e-98 328.9 18.2 4.1e-98 328.6 18.2 1.1 1 0 0 1 1 1 1 Sulfate permease family DUF2530 PF10745.9 KXX77419.1 - 5.3 7.4 8.8 8.4 6.7 0.9 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Pyr_redox_2 PF07992.14 KXX77420.1 - 1e-48 166.1 0.3 1.3e-48 165.7 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXX77420.1 - 3.3e-27 94.9 0.0 2.3e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXX77420.1 - 5e-20 71.8 0.4 1.3e-19 70.5 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX77420.1 - 8.5e-08 31.8 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXX77420.1 - 8e-05 22.0 0.1 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXX77420.1 - 0.00027 20.9 0.1 0.00044 20.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KXX77420.1 - 0.0013 18.9 0.3 0.31 11.3 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KXX77420.1 - 0.0017 18.8 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.14 KXX77420.1 - 0.0037 16.0 1.4 0.85 8.3 0.1 2.5 2 1 1 3 3 3 2 HI0933-like protein TrkA_N PF02254.18 KXX77420.1 - 0.01 16.1 0.1 0.049 13.9 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 KXX77420.1 - 0.017 14.5 0.1 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KXX77420.1 - 0.027 14.1 0.4 0.39 10.2 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXX77420.1 - 0.029 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 KXX77420.1 - 0.14 11.2 2.7 1.6 7.7 0.1 2.9 1 1 2 3 3 3 0 FAD binding domain ABC_tran PF00005.27 KXX77424.1 - 4.4e-49 166.5 0.0 5.9e-29 101.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXX77424.1 - 6.4e-40 137.5 23.2 3.6e-28 99.0 7.6 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KXX77424.1 - 4e-09 36.3 0.0 0.00032 20.2 0.0 4.2 3 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXX77424.1 - 0.00084 19.8 1.1 0.24 11.8 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXX77424.1 - 0.0014 18.7 0.1 0.068 13.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KXX77424.1 - 0.0019 17.9 0.7 2.5 7.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KXX77424.1 - 0.0036 16.4 0.0 0.55 9.2 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KXX77424.1 - 0.0049 16.5 0.0 0.88 9.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXX77424.1 - 0.0053 17.0 1.1 2.3 8.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXX77424.1 - 0.0056 16.6 0.4 2.7 7.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXX77424.1 - 0.01 16.3 0.2 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXX77424.1 - 0.017 14.9 0.1 1.8 8.3 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 KXX77424.1 - 0.076 13.1 3.0 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 KXX77424.1 - 0.089 12.6 0.2 7.4 6.3 0.0 3.3 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 KXX77424.1 - 0.1 11.8 0.2 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.6 KXX77424.1 - 0.17 12.2 0.2 20 5.5 0.0 3.3 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit SprT-like PF10263.9 KXX77425.1 - 3.9e-17 62.1 0.0 6.5e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 SprT-like family TraY PF05509.11 KXX77425.1 - 0.13 12.4 0.3 0.24 11.5 0.3 1.5 1 0 0 1 1 1 0 TraY domain Pkinase PF00069.25 KXX77427.1 - 1.7e-14 53.9 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77427.1 - 0.096 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase WD40 PF00400.32 KXX77428.1 - 6.8e-18 64.7 12.9 0.0016 19.2 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX77428.1 - 3.7e-15 56.0 0.0 0.00042 20.5 0.0 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXX77428.1 - 0.00024 21.1 0.1 0.18 11.7 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KXX77428.1 - 0.0024 17.0 0.0 0.5 9.3 0.0 2.8 2 1 1 3 3 3 2 Coatomer WD associated region Amidase PF01425.21 KXX77429.1 - 1.1e-82 278.5 0.0 1.5e-82 278.0 0.0 1.2 1 0 0 1 1 1 1 Amidase Methyltransf_11 PF08241.12 KXX77429.1 - 0.00014 22.4 0.1 0.0033 18.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77429.1 - 0.12 13.1 0.1 1.3 9.7 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain MaoC_dehydratas PF01575.19 KXX77430.1 - 5.8e-20 71.1 0.0 9.2e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXX77430.1 - 0.00013 22.1 0.0 0.02 15.0 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase PI-PLC-X PF00388.19 KXX77432.1 - 2.2e-06 27.3 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CAP_GLY PF01302.25 KXX77434.1 - 1.6e-19 69.7 0.1 4.1e-19 68.3 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KXX77434.1 - 4.1e-12 46.1 2.8 0.0055 17.1 0.0 5.6 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXX77434.1 - 3.5e-07 29.9 6.3 0.16 11.7 1.7 5.0 3 1 3 6 6 6 3 Leucine rich repeat LRR_9 PF14580.6 KXX77434.1 - 0.00019 21.0 0.1 1.1 8.7 0.0 3.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KXX77434.1 - 0.0005 19.9 8.7 16 5.9 0.0 6.7 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 KXX77434.1 - 0.0049 17.2 3.9 42 5.3 0.1 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat Sds3 PF08598.11 KXX77435.1 - 1.2e-16 61.4 4.9 1.2e-16 61.4 4.9 2.7 3 1 0 3 3 3 1 Sds3-like FA PF08736.11 KXX77435.1 - 1.6 8.9 4.6 2.5 8.3 0.4 3.1 2 0 0 2 2 2 0 FERM adjacent (FA) RRM_1 PF00076.22 KXX77436.1 - 6e-12 45.2 0.0 3.5e-08 33.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tubulin PF00091.25 KXX77437.1 - 1.1e-64 218.3 0.0 1.4e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXX77437.1 - 8.6e-44 148.7 0.0 1.3e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXX77437.1 - 0.0003 20.5 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain GPI-anchored PF10342.9 KXX77438.1 - 6e-20 71.8 0.1 6e-20 71.8 0.1 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Apt1 PF10351.9 KXX77438.1 - 0.3 9.9 3.9 0.38 9.6 3.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.12 KXX77438.1 - 7.6 5.0 10.1 10 4.6 10.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Coiled-coil_56 PF09813.9 KXX77439.1 - 0.00093 19.2 0.0 0.00093 19.2 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 KXX77440.1 - 1.2e-70 237.7 0.1 4e-70 236.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) MFS_1 PF07690.16 KXX77441.1 - 4.7e-22 78.4 44.2 1.8e-19 69.9 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX77441.1 - 3e-13 49.4 18.3 3.2e-12 46.0 18.3 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2347 PF09804.9 KXX77442.1 - 0.17 11.4 1.0 0.29 10.7 0.6 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF1940 PF09155.10 KXX77442.1 - 0.99 9.5 4.2 0.68 10.0 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) zf-CCCH PF00642.24 KXX77443.1 - 2.5e-18 65.5 31.5 8.2e-07 28.8 0.4 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXX77443.1 - 2.5e-17 62.3 32.0 1.4e-06 28.2 1.9 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 KXX77443.1 - 2.9e-09 37.6 29.7 0.00035 21.3 0.5 5.5 2 1 4 6 6 6 4 Torus domain zf-CCCH_4 PF18044.1 KXX77443.1 - 1.4e-08 34.3 33.8 1.2e-05 25.0 0.4 5.4 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXX77443.1 - 0.43 10.8 11.9 7.1 6.9 0.4 3.4 2 1 1 3 3 3 0 Zinc-finger containing family TSP9 PF11493.8 KXX77443.1 - 1.1 10.0 4.3 0.25 12.0 0.5 1.9 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Gag_spuma PF03276.14 KXX77443.1 - 2.4 6.5 5.4 3.1 6.1 5.4 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1776 PF08643.10 KXX77444.1 - 2.9e-113 378.2 0.0 3.7e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KXX77444.1 - 0.08 12.4 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase DUF1772 PF08592.11 KXX77445.1 - 2.6e-31 108.8 7.0 3.2e-31 108.5 7.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pyr_redox_2 PF07992.14 KXX77446.1 - 2.4e-51 174.7 1.1 4.3e-51 173.9 1.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KXX77446.1 - 5.7e-32 110.4 1.2 5.7e-32 110.4 1.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox PF00070.27 KXX77446.1 - 1.4e-18 67.2 2.0 2e-16 60.3 0.6 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX77446.1 - 4.9e-17 62.1 0.0 2.3e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 KXX77446.1 - 1.3e-12 48.9 0.3 4.3e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KXX77446.1 - 6.4e-05 23.1 0.1 0.066 13.5 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KXX77446.1 - 0.00012 22.5 0.9 0.014 15.8 0.1 2.9 3 0 0 3 3 2 1 Putative NAD(P)-binding ADH_N PF08240.12 KXX77446.1 - 0.00018 21.3 0.0 0.00076 19.3 0.0 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thi4 PF01946.17 KXX77446.1 - 0.00022 20.5 0.1 0.0018 17.6 0.0 2.5 3 0 0 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.21 KXX77446.1 - 0.0003 20.2 3.6 0.015 14.6 0.6 3.4 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXX77446.1 - 0.0006 19.3 0.1 0.0077 15.6 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KXX77446.1 - 0.00072 18.7 1.0 0.94 8.5 0.1 3.9 4 0 0 4 4 4 1 Glucose inhibited division protein A DAO PF01266.24 KXX77446.1 - 0.00082 19.1 0.6 2.8 7.4 0.0 3.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXX77446.1 - 0.0011 18.3 1.2 6.4 5.9 0.1 3.2 2 1 1 3 3 3 2 FAD binding domain K_oxygenase PF13434.6 KXX77446.1 - 0.0058 15.8 0.1 0.85 8.7 0.1 3.2 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 KXX77446.1 - 0.028 14.7 3.4 0.12 12.7 0.1 3.2 4 1 0 4 4 3 0 TrkA-N domain ADH_N_2 PF16884.5 KXX77446.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Trp_halogenase PF04820.14 KXX77446.1 - 0.081 11.8 0.7 0.91 8.3 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KXX77446.1 - 0.12 11.5 9.8 0.17 10.9 0.3 3.8 3 2 2 5 5 5 0 FAD binding domain Shikimate_DH PF01488.20 KXX77446.1 - 0.12 12.5 0.4 22 5.1 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KXX77446.1 - 0.21 10.2 2.0 2.7 6.6 0.1 3.2 3 1 1 4 4 4 0 HI0933-like protein Rab5ip PF07019.12 KXX77447.1 - 1.7e-31 108.6 7.5 2e-31 108.4 7.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) RL11D PF11088.8 KXX77447.1 - 0.18 12.1 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Vezatin PF12632.7 KXX77448.1 - 7.2e-77 258.5 0.1 1.3e-76 257.6 0.1 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF2550 PF10739.9 KXX77448.1 - 0.019 15.0 0.0 0.057 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) PET117 PF15786.5 KXX77448.1 - 0.31 11.3 0.1 0.31 11.3 0.1 2.6 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial CENP-F_leu_zip PF10473.9 KXX77448.1 - 1.4 9.0 7.2 0.12 12.4 0.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Zn_clus PF00172.18 KXX77449.1 - 4.2e-08 33.2 10.3 6.8e-08 32.5 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX77449.1 - 0.00056 18.8 0.6 0.00091 18.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.20 KXX77450.1 - 5.4e-139 463.0 0.4 6.1e-139 462.8 0.4 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXX77450.1 - 5.2e-07 29.2 0.2 8e-07 28.5 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXX77450.1 - 2.7e-06 26.6 0.6 2.7e-06 26.6 0.6 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXX77450.1 - 1.1e-05 25.0 0.4 2e-05 24.1 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KXX77450.1 - 0.0009 18.6 0.3 0.0019 17.5 0.3 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KXX77450.1 - 0.0061 15.4 0.2 0.0061 15.4 0.2 1.4 2 0 0 2 2 2 1 Glycine cleavage system P-protein Big_3_5 PF16640.5 KXX77450.1 - 3.5 7.9 8.0 7 6.9 4.6 2.5 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) KH_1 PF00013.29 KXX77452.1 - 1.9e-44 149.3 6.9 3.1e-18 65.3 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXX77452.1 - 1.4e-13 50.5 4.8 0.0024 17.7 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXX77452.1 - 6e-06 26.0 2.6 0.33 10.8 0.2 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KXX77452.1 - 3.6e-05 23.7 0.0 0.0093 15.9 0.0 2.8 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KXX77452.1 - 8.9e-05 22.5 9.2 0.33 11.1 0.3 3.4 3 0 0 3 3 3 3 NusA-like KH domain CENP-K PF11802.8 KXX77453.1 - 1.8e-15 57.2 2.8 2.9e-08 33.6 0.0 2.2 2 1 0 2 2 2 2 Centromere-associated protein K AAA_13 PF13166.6 KXX77453.1 - 0.068 11.8 4.3 0.012 14.3 0.9 1.5 2 0 0 2 2 2 0 AAA domain IF-2B PF01008.17 KXX77453.1 - 0.68 9.1 3.0 1.2 8.2 3.0 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family APG6_N PF17675.1 KXX77453.1 - 4.5 7.8 18.4 1.9 9.0 9.5 3.0 3 0 0 3 3 3 0 Apg6 coiled-coil region Atg14 PF10186.9 KXX77453.1 - 8.4 5.4 18.5 1.7 7.7 10.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 dUTPase PF00692.19 KXX77454.1 - 1.1e-46 157.7 0.0 1.3e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF1765 PF08578.10 KXX77455.1 - 4.4e-46 156.4 1.2 6.8e-46 155.8 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) K_channel_TID PF07941.11 KXX77455.1 - 0.27 11.7 4.0 1.5 9.3 4.0 2.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SBF PF01758.16 KXX77456.1 - 5.7e-50 169.7 11.2 5.7e-50 169.7 11.2 1.7 2 1 0 2 2 2 1 Sodium Bile acid symporter family TM_helix PF05552.12 KXX77457.1 - 0.003 17.5 0.5 0.0071 16.3 0.5 1.7 1 0 0 1 1 1 1 Conserved TM helix CHASE3 PF05227.13 KXX77457.1 - 0.032 14.1 0.6 0.067 13.1 0.6 1.5 1 0 0 1 1 1 0 CHASE3 domain YlbD_coat PF14071.6 KXX77457.1 - 0.14 12.4 0.8 0.28 11.4 0.8 1.5 1 0 0 1 1 1 0 Putative coat protein Peptidase_C12 PF01088.21 KXX77458.1 - 6.9e-48 163.2 0.0 8e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PCNA_N PF00705.18 KXX77459.1 - 8.7e-58 193.5 4.5 2.9e-57 191.9 3.8 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KXX77459.1 - 3.3e-51 172.8 0.3 1.8e-50 170.4 0.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KXX77459.1 - 1e-08 35.0 0.1 1.2e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KXX77459.1 - 1.4e-06 27.6 1.6 8.8e-05 21.7 0.6 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KXX77459.1 - 1.9e-05 23.9 0.2 0.0021 17.2 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein DNA_pol3_beta_3 PF02768.15 KXX77459.1 - 0.085 12.7 0.2 0.45 10.4 0.1 2.2 2 1 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain KAR9 PF08580.10 KXX77461.1 - 1.6e-186 621.9 15.5 1.6e-186 621.9 15.5 2.9 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Cnn_1N PF07989.11 KXX77461.1 - 0.012 15.8 2.5 0.56 10.4 0.0 2.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Prominin PF05478.11 KXX77461.1 - 0.21 9.5 2.3 0.64 7.9 0.3 2.0 2 0 0 2 2 2 0 Prominin DUF4618 PF15397.6 KXX77461.1 - 1.2 8.5 7.7 0.094 12.1 1.8 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) THOC7 PF05615.13 KXX77461.1 - 1.7 8.9 9.5 1.6 9.0 4.2 3.1 2 1 0 2 2 2 0 Tho complex subunit 7 Syntaxin-6_N PF09177.11 KXX77461.1 - 2 9.0 10.8 5.9 7.5 0.7 3.8 2 2 1 3 3 3 0 Syntaxin 6, N-terminal FliT PF05400.13 KXX77461.1 - 3.7 8.4 13.3 5.9 7.8 0.9 3.7 3 0 0 3 3 3 0 Flagellar protein FliT Ank_2 PF12796.7 KXX77462.1 - 1.2e-40 138.0 2.2 1.6e-13 51.0 0.0 9.7 5 2 4 9 9 9 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX77462.1 - 3e-32 107.0 7.6 0.0065 16.9 0.0 13.9 16 0 0 16 16 16 7 Ankyrin repeat Ank_4 PF13637.6 KXX77462.1 - 1.3e-27 95.8 7.9 1.7e-05 25.3 0.0 11.3 10 3 3 13 13 13 6 Ankyrin repeats (many copies) Ank PF00023.30 KXX77462.1 - 5e-22 77.3 7.4 0.00084 19.7 0.0 9.5 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 KXX77462.1 - 5.2e-17 61.7 18.0 0.037 14.4 0.2 10.4 10 2 2 12 12 12 5 Ankyrin repeats (many copies) Tim44 PF04280.15 KXX77462.1 - 0.2 11.7 1.1 43 4.2 0.0 3.2 3 0 0 3 3 3 0 Tim44-like domain DUF1282 PF06930.12 KXX77463.1 - 0.0028 17.4 0.1 0.0032 17.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF4064 PF13273.6 KXX77463.1 - 0.0086 16.3 1.4 0.027 14.7 1.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4064) Brix PF04427.18 KXX77464.1 - 9.4e-39 133.5 0.1 1.2e-38 133.2 0.1 1.1 1 0 0 1 1 1 1 Brix domain MFS_1 PF07690.16 KXX77465.1 - 1e-26 93.7 21.0 1.4e-26 93.2 21.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.11 KXX77466.1 - 1.2e-42 146.0 12.6 1.5e-42 145.7 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DEAD PF00270.29 KXX77467.1 - 2.7e-19 69.6 0.0 7e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX77467.1 - 6.4e-18 65.1 0.0 7e-16 58.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXX77467.1 - 3.7e-17 62.8 5.4 1.2e-16 61.1 5.2 2.2 2 0 0 2 2 2 1 RecQ zinc-binding RQC PF09382.10 KXX77467.1 - 3.2e-09 36.6 0.0 6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 KXX77467.1 - 0.004 17.1 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 HRDC domain SecA_DEAD PF07517.14 KXX77467.1 - 0.029 13.7 0.0 0.077 12.3 0.0 1.7 1 0 0 1 1 1 0 SecA DEAD-like domain PBP1_TM PF14812.6 KXX77467.1 - 2.1 8.8 10.6 2.8 8.4 3.6 3.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phos_pyr_kin PF08543.12 KXX77468.1 - 6.6e-11 42.1 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXX77468.1 - 6.7e-06 25.6 0.1 6.3e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 pfkB family carbohydrate kinase betaPIX_CC PF16523.5 KXX77469.1 - 0.0035 17.1 0.3 0.0079 16.0 0.3 1.5 1 0 0 1 1 1 1 betaPIX coiled coil Lzipper-MIP1 PF14389.6 KXX77469.1 - 0.032 14.5 0.4 0.089 13.1 0.4 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 KXX77469.1 - 0.18 11.6 2.3 0.44 10.4 2.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Mito_carr PF00153.27 KXX77470.1 - 6.1e-65 215.2 0.3 2.6e-20 72.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXX77470.1 - 0.62 9.2 3.2 3.9 6.5 0.1 3.1 4 0 0 4 4 4 0 Gammaproteobacterial serine protease ApoO PF09769.9 KXX77471.1 - 5.3e-44 149.3 3.3 1.1e-42 145.0 0.1 2.7 3 0 0 3 3 3 2 Apolipoprotein O CAP_GLY PF01302.25 KXX77472.1 - 3.1e-16 59.1 0.2 8.4e-16 57.8 0.2 1.8 2 0 0 2 2 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KXX77472.1 - 1.2e-06 28.2 9.1 0.00046 20.0 1.3 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle AAA_13 PF13166.6 KXX77472.1 - 0.00091 18.0 9.8 0.00091 18.0 9.8 2.1 2 1 0 2 2 2 1 AAA domain BLOC1_2 PF10046.9 KXX77472.1 - 0.0061 16.8 2.8 0.0061 16.8 2.8 3.6 4 0 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med4 PF10018.9 KXX77472.1 - 0.013 15.1 1.7 0.013 15.1 1.7 3.3 3 2 1 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.12 KXX77472.1 - 0.014 15.8 6.5 0.1 13.1 1.4 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Glutaredoxin2_C PF04399.13 KXX77472.1 - 0.051 13.4 3.3 4.9 7.0 0.7 2.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Spc7 PF08317.11 KXX77472.1 - 0.19 10.5 31.2 0.64 8.8 11.9 3.5 2 1 2 4 4 4 0 Spc7 kinetochore protein Pkip-1 PF06878.11 KXX77472.1 - 0.38 10.8 7.1 4.2 7.5 0.2 2.3 1 1 1 2 2 2 0 Pkip-1 protein DUF3584 PF12128.8 KXX77472.1 - 0.44 8.0 24.1 0.98 6.8 24.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 KXX77472.1 - 0.45 10.8 1.4 1.8 8.9 1.4 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 KXX77472.1 - 0.54 9.1 29.2 0.068 12.0 16.3 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 KXX77472.1 - 0.64 10.0 4.6 1 9.4 2.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.13 KXX77472.1 - 0.68 8.2 28.5 0.2 10.0 21.1 2.5 2 1 0 2 2 2 0 Mitotic checkpoint protein HrpB7 PF09486.10 KXX77472.1 - 0.91 9.9 31.9 7.4 6.9 18.4 3.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) zf_PR_Knuckle PF18445.1 KXX77472.1 - 1.9 8.4 4.1 13 5.7 0.3 2.4 2 0 0 2 2 2 0 PR zinc knuckle motif DASH_Dam1 PF08653.10 KXX77472.1 - 2.6 7.9 3.7 4.3 7.2 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Cauli_AT PF03233.13 KXX77472.1 - 3.7 7.5 4.4 1.7 8.5 1.4 2.0 2 0 0 2 2 2 0 Aphid transmission protein MscS_porin PF12795.7 KXX77472.1 - 4.2 6.9 25.7 0.91 9.0 9.1 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF1660 PF07874.11 KXX77473.1 - 0.12 12.9 0.7 7 7.2 0.0 2.9 2 1 0 2 2 2 0 Prophage protein (DUF1660) IU_nuc_hydro PF01156.19 KXX77474.1 - 8.1e-79 265.3 0.0 9.7e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.25 KXX77475.1 - 2.6e-33 115.5 0.0 7.7e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77475.1 - 1.8e-11 43.9 0.0 6e-10 38.8 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXX77475.1 - 1.7e-06 28.1 0.0 3.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXX77475.1 - 0.0047 16.3 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like IMS PF00817.20 KXX77476.1 - 2.9e-40 137.7 0.0 5.9e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KXX77476.1 - 1.1e-26 93.1 4.3 2.3e-26 92.0 4.3 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 KXX77476.1 - 7.9e-16 56.9 11.2 4.1e-07 29.2 0.3 3.9 3 0 0 3 3 3 3 Ubiquitin binding region IMS_C PF11799.8 KXX77476.1 - 3.3e-14 53.6 0.0 7.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KXX77476.1 - 2.3e-07 31.2 0.0 9.2e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain mCpol PF18182.1 KXX77476.1 - 0.00088 19.6 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain MgtE_N PF03448.17 KXX77476.1 - 0.0015 19.1 0.1 12 6.6 0.0 4.1 4 0 0 4 4 4 1 MgtE intracellular N domain LIG3_BRCT PF16759.5 KXX77476.1 - 0.003 17.8 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 KXX77476.1 - 0.013 15.8 1.0 0.053 13.9 0.2 2.5 2 0 0 2 2 2 0 IMS family HHH motif DUF1805 PF08827.11 KXX77476.1 - 0.047 14.0 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FliG_M PF14841.6 KXX77476.1 - 0.2 11.9 0.9 77 3.6 0.0 3.9 4 0 0 4 4 4 0 FliG middle domain RED_N PF07808.13 KXX77477.1 - 1.8e-08 34.3 13.3 1.8e-08 34.3 13.3 2.6 2 1 0 2 2 2 1 RED-like protein N-terminal region DUF2924 PF11149.8 KXX77477.1 - 7.4 7.0 11.8 0.11 12.9 2.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2924) Peptidase_M3 PF01432.20 KXX77478.1 - 6.6e-118 394.9 0.0 1.2e-117 394.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KXX77478.1 - 0.029 14.0 0.1 0.048 13.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Spore_III_AB PF09548.10 KXX77478.1 - 0.13 12.3 0.1 0.44 10.7 0.1 1.9 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) WSC PF01822.19 KXX77479.1 - 1.8e-16 60.1 8.9 2.9e-16 59.4 8.9 1.3 1 0 0 1 1 1 1 WSC domain DUF202 PF02656.15 KXX77480.1 - 1.5e-21 76.6 1.8 1.5e-21 76.6 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Sod_Fe_C PF02777.18 KXX77481.1 - 1.7e-12 47.4 0.0 3.4e-05 23.9 0.0 2.6 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain MRI PF15325.6 KXX77482.1 - 4.2 8.5 12.8 2 9.5 3.1 2.7 2 1 0 2 2 2 0 Modulator of retrovirus infection Ank_2 PF12796.7 KXX77483.1 - 5.7e-56 187.1 5.6 4.6e-19 68.8 0.3 5.1 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77483.1 - 2.4e-46 155.5 14.5 1.2e-11 44.9 0.0 9.0 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KXX77483.1 - 1.5e-39 132.7 8.0 2e-06 28.0 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KXX77483.1 - 2.7e-33 113.6 7.5 1.4e-10 41.2 0.3 6.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77483.1 - 3.7e-30 100.6 7.3 0.00052 20.3 0.0 8.1 9 0 0 9 9 7 6 Ankyrin repeat NACHT PF05729.12 KXX77483.1 - 1.9e-07 31.1 0.1 5e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXX77483.1 - 2.6e-06 27.7 0.0 8e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX77483.1 - 7.9e-06 26.4 2.4 1e-05 26.0 0.1 2.4 3 0 0 3 3 2 1 AAA ATPase domain AAA PF00004.29 KXX77483.1 - 0.0063 16.9 0.0 0.026 15.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KXX77483.1 - 0.02 14.2 2.3 0.29 10.3 0.1 2.7 2 1 1 3 3 3 0 KAP family P-loop domain ABC_tran PF00005.27 KXX77483.1 - 0.042 14.4 0.0 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KXX77483.1 - 0.049 14.0 0.0 0.19 12.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KXX77483.1 - 0.052 13.7 0.1 0.52 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXX77483.1 - 0.11 11.7 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain SHR3_chaperone PF08229.11 KXX77484.1 - 2.4e-72 241.9 0.0 2.7e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2157 PF09925.9 KXX77484.1 - 0.0029 17.4 1.0 2.8 7.7 0.6 3.1 2 1 1 3 3 3 2 Predicted membrane protein (DUF2157) Ni_hydr_CYTB PF01292.20 KXX77484.1 - 0.041 13.5 1.1 0.072 12.7 0.3 1.8 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Fungal_trans_2 PF11951.8 KXX77485.1 - 4.9e-83 279.1 0.0 6e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX77485.1 - 2.1e-07 31.0 5.2 3.5e-07 30.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_38N PF01074.22 KXX77486.1 - 3.3e-88 295.8 0.6 6.3e-88 294.9 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KXX77486.1 - 8.9e-60 202.4 1.4 2.3e-59 201.1 0.6 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXX77486.1 - 5.8e-27 93.7 0.0 1.5e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXX77486.1 - 7.2e-08 32.4 0.0 2.9e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KXX77486.1 - 0.051 12.8 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 AAA_11 PF13086.6 KXX77487.1 - 9e-59 199.4 0.2 2.1e-58 198.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KXX77487.1 - 3.3e-55 186.8 0.0 7.3e-55 185.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXX77487.1 - 8.2e-11 42.0 0.0 1.6e-09 37.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX77487.1 - 1.5e-07 31.8 0.0 8.9e-07 29.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KXX77487.1 - 8.3e-07 28.6 0.1 4e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KXX77487.1 - 2e-06 27.7 0.0 0.74 9.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXX77487.1 - 3.2e-05 23.6 0.0 0.00015 21.4 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KXX77487.1 - 7.8e-05 22.7 0.0 0.00044 20.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXX77487.1 - 0.00089 19.5 0.1 0.0087 16.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX77487.1 - 0.0012 19.3 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KXX77487.1 - 0.0028 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 KXX77487.1 - 0.0028 17.5 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_25 PF13481.6 KXX77487.1 - 0.0032 17.1 0.2 0.22 11.0 0.0 3.1 2 1 1 3 3 3 1 AAA domain Flavi_DEAD PF07652.14 KXX77487.1 - 0.0036 17.3 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain DEAD PF00270.29 KXX77487.1 - 0.0046 16.7 0.0 0.058 13.2 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KXX77487.1 - 0.005 16.3 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 KXX77487.1 - 0.005 17.3 0.0 0.029 14.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX77487.1 - 0.0058 16.8 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KXX77487.1 - 0.029 14.2 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 KXX77487.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 KXX77487.1 - 0.041 12.8 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 KXX77487.1 - 0.055 13.2 0.0 0.25 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain 4HB_MCP_1 PF12729.7 KXX77487.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction UvrD_C PF13361.6 KXX77487.1 - 0.06 12.7 0.0 2.7 7.3 0.0 2.6 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 KXX77487.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein SAM_2 PF07647.17 KXX77488.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXX77488.1 - 0.00013 22.3 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KXX77488.1 - 0.0002 21.8 0.0 0.0038 17.7 0.0 2.8 2 1 0 2 2 2 1 PH domain Aldo_ket_red PF00248.21 KXX77489.1 - 2.7e-54 184.4 0.0 3.4e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MGC-24 PF05283.11 KXX77490.1 - 0.0012 19.3 0.9 0.0028 18.1 0.9 1.6 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KXX77490.1 - 0.004 17.1 0.1 0.0064 16.4 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family Insulin_TMD PF17870.1 KXX77490.1 - 0.022 14.8 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 KXX77490.1 - 0.079 13.9 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Nop14 PF04147.12 KXX77491.1 - 8.9e-304 1010.2 27.3 1.1e-303 1009.8 27.3 1.1 1 0 0 1 1 1 1 Nop14-like family RVT_2 PF07727.14 KXX77492.1 - 9.4e-44 149.9 0.0 1.4e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KXX77493.1 - 1.5e-05 24.7 0.2 2.7e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KXX77493.1 - 0.00092 19.0 0.7 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain DUF2795 PF11387.8 KXX77493.1 - 0.001 19.2 0.1 0.067 13.4 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2795) Cript PF10235.9 KXX77493.1 - 0.0065 17.0 2.2 0.051 14.1 0.7 2.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT FYVE PF01363.21 KXX77493.1 - 0.0091 16.1 1.4 0.011 15.9 0.3 1.7 2 0 0 2 2 2 1 FYVE zinc finger zinc_ribbon_15 PF17032.5 KXX77493.1 - 0.017 15.9 1.8 0.41 11.4 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon family DZR PF12773.7 KXX77493.1 - 0.036 14.1 2.4 0.14 12.2 0.6 2.2 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbon_6 PF10005.9 KXX77493.1 - 0.049 14.3 3.1 0.19 12.4 1.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KXX77493.1 - 0.39 10.2 6.0 0.055 12.9 1.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 KXX77493.1 - 0.59 10.3 3.7 1.3 9.3 1.1 2.8 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like ketoacyl-synt PF00109.26 KXX77494.1 - 8e-77 258.2 0.0 1.4e-76 257.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXX77494.1 - 7.7e-55 186.2 0.2 1.4e-53 182.0 0.2 2.2 1 1 0 1 1 1 1 AMP-binding enzyme KR PF08659.10 KXX77494.1 - 1.1e-53 181.8 0.0 8.9e-52 175.6 0.0 2.5 2 0 0 2 2 2 1 KR domain Condensation PF00668.20 KXX77494.1 - 2.6e-51 174.7 0.1 3.9e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KXX77494.1 - 1.3e-48 165.8 0.0 2.4e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX77494.1 - 6.4e-41 140.9 0.3 1.3e-40 139.9 0.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX77494.1 - 2.4e-28 98.5 0.0 5.3e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXX77494.1 - 9.6e-28 97.0 0.0 1.3e-26 93.3 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KXX77494.1 - 1.8e-17 63.9 0.0 1.1e-16 61.4 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXX77494.1 - 1.7e-15 57.4 0.0 4.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KXX77494.1 - 3.4e-13 49.6 0.0 9e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXX77494.1 - 9.6e-13 48.3 3.0 2.9e-06 27.5 0.2 3.7 4 0 0 4 4 3 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KXX77494.1 - 3.7e-10 40.4 0.0 5.8e-09 36.5 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77494.1 - 1.9e-09 38.0 0.0 6.9e-09 36.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX77494.1 - 9.7e-09 35.0 0.0 7.9e-08 32.0 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KXX77494.1 - 1.9e-08 34.3 0.0 3.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX77494.1 - 2.8e-05 23.9 0.0 7.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 KXX77494.1 - 8.5e-05 22.5 0.0 0.002 18.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H-binding Thiolase_N PF00108.23 KXX77494.1 - 0.00011 21.7 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KXX77494.1 - 0.0063 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.19 KXX77494.1 - 0.14 11.2 0.0 0.98 8.4 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXX77494.1 - 0.15 11.5 0.0 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KXX77494.1 - 0.18 11.1 0.0 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Zn_clus PF00172.18 KXX77496.1 - 3.5e-06 27.0 6.7 6.5e-06 26.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SLAC1 PF03595.17 KXX77499.1 - 2.9e-73 246.9 43.6 3.4e-73 246.7 43.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CorA PF01544.18 KXX77500.1 - 6.7e-08 32.2 0.2 6.7e-08 32.2 0.2 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Ureide_permease PF07168.11 KXX77500.1 - 0.012 14.4 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 0 Ureide permease Ammonium_transp PF00909.21 KXX77500.1 - 0.043 12.5 1.6 0.057 12.1 1.6 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family Patched PF02460.18 KXX77500.1 - 0.47 8.5 5.1 5.1 5.0 0.1 2.1 1 1 1 2 2 2 0 Patched family CD225 PF04505.12 KXX77500.1 - 0.82 9.9 0.1 0.82 9.9 0.1 2.6 3 1 0 3 3 3 0 Interferon-induced transmembrane protein DUF3429 PF11911.8 KXX77501.1 - 2.8e-43 147.7 10.3 3.7e-43 147.3 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Peptidase_S49_N PF08496.10 KXX77501.1 - 0.0098 16.0 4.8 0.019 15.0 4.8 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Transgly_assoc PF04226.13 KXX77501.1 - 0.11 12.7 2.4 0.48 10.7 0.2 2.3 2 0 0 2 2 2 0 Transglycosylase associated protein DUF4834 PF16118.5 KXX77501.1 - 0.12 13.4 2.5 0.18 12.8 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) U79_P34 PF03064.16 KXX77501.1 - 1.1 8.5 11.6 1.7 8.0 11.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4770 PF15994.5 KXX77501.1 - 9.9 6.4 8.3 27 4.9 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAD_binding_3 PF01494.19 KXX77502.1 - 3.5e-16 59.4 0.0 7.5e-16 58.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX77502.1 - 1.1e-06 28.5 0.0 0.044 13.4 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX77502.1 - 4.1e-06 26.2 0.0 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX77502.1 - 0.00029 21.3 0.0 0.035 14.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXX77502.1 - 0.0017 17.3 0.0 0.3 9.9 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KXX77502.1 - 0.02 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 KXX77502.1 - 0.25 10.4 0.0 1.8 7.6 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase SHR-BD PF06650.12 KXX77503.1 - 4.8e-82 275.4 0.0 8.1e-82 274.6 0.0 1.4 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 KXX77503.1 - 2.1e-77 258.9 5.4 1.4e-71 239.9 0.3 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KXX77503.1 - 1.2e-07 32.0 0.0 4.9e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Amidase PF01425.21 KXX77504.1 - 7.7e-91 305.3 0.0 1.3e-90 304.6 0.0 1.3 1 1 0 1 1 1 1 Amidase Ank_2 PF12796.7 KXX77505.1 - 1.1e-37 128.5 0.0 2e-09 37.9 0.0 5.1 3 3 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX77505.1 - 9.2e-27 90.2 0.3 0.011 16.2 0.0 9.3 8 1 1 9 9 9 7 Ankyrin repeat Ank PF00023.30 KXX77505.1 - 1.1e-24 85.7 0.5 0.00013 22.3 0.0 8.4 8 1 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 KXX77505.1 - 1.4e-22 79.7 0.3 1.2e-09 38.5 0.0 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX77505.1 - 6.2e-22 77.4 4.0 0.0014 18.9 0.0 6.2 4 2 2 6 6 6 6 Ankyrin repeats (many copies) zf-C2H2_12 PF18658.1 KXX77505.1 - 0.0013 18.2 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger C2H2-type WhiA_N PF10298.9 KXX77505.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain VHL_C PF17211.3 KXX77505.1 - 0.26 11.3 1.7 0.44 10.6 0.5 2.0 2 0 0 2 2 2 0 VHL box domain WSC PF01822.19 KXX77507.1 - 4.3e-07 30.0 0.2 5.5e-07 29.7 0.2 1.1 1 0 0 1 1 1 1 WSC domain p450 PF00067.22 KXX77508.1 - 4.7e-48 164.1 0.0 5.3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXX77509.1 - 3.2e-12 45.9 0.0 4.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 VPS13_mid_rpt PF16910.5 KXX77510.1 - 4.4e-91 304.5 22.7 4.5e-90 301.2 0.3 5.9 6 1 1 7 7 7 4 Repeating coiled region of VPS13 VPS13 PF16908.5 KXX77510.1 - 7e-88 294.4 0.0 6.2e-86 288.0 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KXX77510.1 - 8.6e-40 135.5 0.1 3.4e-39 133.6 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 KXX77510.1 - 4.6e-06 26.2 0.0 0.00025 20.5 0.0 2.7 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 HLH PF00010.26 KXX77513.1 - 6e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.29 KXX77514.1 - 1.9e-11 44.5 0.0 3.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX77514.1 - 8.9e-06 26.0 0.1 2.9e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXX77514.1 - 8e-05 22.4 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXX77514.1 - 0.00016 21.9 0.2 0.00087 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXX77514.1 - 0.00042 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 KXX77514.1 - 0.00056 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXX77514.1 - 0.0015 18.9 0.7 0.013 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KXX77514.1 - 0.0025 17.0 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KXX77514.1 - 0.0039 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXX77514.1 - 0.021 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXX77514.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KXX77514.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_60s PF00428.19 KXX77514.1 - 3.5 8.3 14.5 7.1 7.3 0.1 4.5 4 0 0 4 4 4 0 60s Acidic ribosomal protein RPAP2_Rtr1 PF04181.13 KXX77515.1 - 2.4e-19 69.4 0.0 2.4e-19 69.4 0.0 2.3 2 0 0 2 2 2 1 Rtr1/RPAP2 family Zip PF02535.22 KXX77515.1 - 0.0049 16.1 1.7 0.0049 16.1 1.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2722 PF10846.8 KXX77515.1 - 0.0099 14.9 19.3 0.0099 14.9 19.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Ndc1_Nup PF09531.10 KXX77515.1 - 0.34 9.5 10.1 0.49 9.0 10.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spem1 PF15670.5 KXX77515.1 - 0.42 10.2 12.4 0.99 8.9 12.4 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 SpoIIP PF07454.11 KXX77515.1 - 0.46 9.9 8.4 0.81 9.1 8.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 KXX77515.1 - 0.78 9.7 33.2 0.31 11.0 28.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Gastrin PF00918.17 KXX77515.1 - 1.2 10.1 12.0 0.82 10.6 9.5 1.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family AXIN1_TNKS_BD PF16646.5 KXX77515.1 - 1.3 10.0 10.5 16 6.5 0.0 3.5 3 0 0 3 3 3 0 Axin-1 tankyrase binding domain EOS1 PF12326.8 KXX77515.1 - 1.5 8.7 2.9 2.6 7.9 2.9 1.3 1 0 0 1 1 1 0 N-glycosylation protein SelP_N PF04592.14 KXX77515.1 - 1.6 8.1 16.7 2.7 7.4 16.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3399 PF11879.8 KXX77515.1 - 2.1 8.7 16.6 8.7 6.7 16.6 2.0 1 1 1 2 2 1 0 Domain of unknown function (DUF3399) PAT1 PF09770.9 KXX77515.1 - 2.1 6.5 25.4 3.5 5.8 25.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF73-100_C PF11718.8 KXX77515.1 - 3.9 7.0 8.6 6.7 6.2 8.6 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term ALMT PF11744.8 KXX77515.1 - 3.9 6.2 6.2 5.3 5.7 6.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter GREB1 PF15782.5 KXX77515.1 - 5.3 4.0 11.5 6.6 3.7 11.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Folate_carrier PF01770.18 KXX77515.1 - 5.6 5.6 7.0 7.8 5.1 7.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier GET2 PF08690.10 KXX77515.1 - 5.7 6.5 12.1 11 5.6 12.1 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3292 PF11696.8 KXX77515.1 - 6.8 4.9 13.5 11 4.3 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Tim54 PF11711.8 KXX77515.1 - 7 5.3 11.8 12 4.5 11.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 OATP PF03137.20 KXX77515.1 - 8 4.6 5.7 12 4.0 5.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Band_3_cyto PF07565.13 KXX77515.1 - 8.1 6.2 12.0 3 7.6 9.2 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 KXX77515.1 - 8.1 5.3 14.4 0.84 8.5 10.3 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 KXX77515.1 - 8.5 6.4 15.3 17 5.4 15.3 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SH3_1 PF00018.28 KXX77517.1 - 8.3e-12 44.5 0.3 3.1e-11 42.7 0.3 2.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX77517.1 - 5.6e-10 38.9 0.3 4.4e-09 36.1 0.3 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXX77517.1 - 2.5e-08 33.5 0.0 8.1e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Fas_alpha_ACP PF18325.1 KXX77518.1 - 1.6e-76 256.2 0.0 3.1e-76 255.2 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KXX77518.1 - 7.3e-75 251.1 0.2 2.2e-74 249.5 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KXX77518.1 - 9.6e-23 81.0 0.1 2.3e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KXX77518.1 - 5.4e-18 65.2 0.0 1.3e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KXX77518.1 - 1.5e-11 44.4 0.0 5.4e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KXX77518.1 - 0.00037 20.0 0.0 0.00084 18.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX77518.1 - 0.011 15.6 0.0 0.048 13.6 0.0 2.2 1 0 0 1 1 1 0 KR domain DUF1729 PF08354.10 KXX77519.1 - 4.8e-155 515.8 0.0 7.4e-155 515.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KXX77519.1 - 4.9e-90 302.3 0.0 3.3e-87 293.0 0.0 3.8 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KXX77519.1 - 3.5e-53 179.3 0.0 9e-53 178.0 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 KXX77519.1 - 2.5e-40 137.5 0.0 7.7e-40 135.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta SAT PF16073.5 KXX77519.1 - 1.8e-39 135.9 0.1 6e-39 134.2 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KXX77519.1 - 1.7e-38 131.0 0.0 3.9e-38 129.8 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXX77519.1 - 1.2e-25 90.2 0.1 5.7e-25 88.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Collagen PF01391.18 KXX77519.1 - 0.55 10.0 4.3 1.2 9.0 4.3 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Aminotran_5 PF00266.19 KXX77520.1 - 6.9e-32 110.8 0.0 4.6e-30 104.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Amidohydro_1 PF01979.20 KXX77521.1 - 1.3e-74 251.6 0.0 1.5e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXX77521.1 - 2.7e-08 33.7 1.5 1.7e-05 24.5 0.4 2.5 2 1 0 2 2 2 2 Amidohydrolase family DUF2373 PF10180.9 KXX77522.1 - 0.0066 16.3 0.1 0.026 14.4 0.0 1.9 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) NMD3 PF04981.13 KXX77522.1 - 0.01 15.3 0.3 0.02 14.4 0.3 1.5 1 0 0 1 1 1 0 NMD3 family Rsa3 PF14615.6 KXX77522.1 - 0.022 14.3 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 Ribosome-assembly protein 3 DZR PF12773.7 KXX77522.1 - 0.13 12.3 1.7 8.5 6.5 0.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon Ank_2 PF12796.7 KXX77523.1 - 5e-32 110.3 12.8 2.2e-05 24.9 0.0 13.8 12 2 2 14 14 14 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX77523.1 - 8.9e-17 59.5 11.3 0.23 12.2 0.0 15.9 17 0 0 17 17 17 1 Ankyrin repeat Ank_4 PF13637.6 KXX77523.1 - 1.3e-14 54.3 14.2 0.027 15.1 0.0 13.7 12 5 4 16 16 16 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX77523.1 - 2.1e-09 37.5 9.6 0.0003 21.0 0.0 9.1 9 2 1 10 10 10 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX77523.1 - 1.7e-07 31.3 18.6 0.031 14.7 0.0 11.6 15 0 0 15 15 15 1 Ankyrin repeat DUF4761 PF15958.5 KXX77523.1 - 0.035 14.2 0.1 0.09 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Sulfate_transp PF00916.20 KXX77524.1 - 1.2e-113 379.7 17.4 1.6e-113 379.4 17.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXX77524.1 - 1.7e-09 37.3 0.0 3.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXX77524.1 - 0.00062 20.2 2.8 0.00062 20.2 2.8 3.1 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KXX77524.1 - 0.0027 18.0 0.4 0.01 16.2 0.4 2.0 1 0 0 1 1 1 1 STAS domain MreB_Mbl PF06723.13 KXX77524.1 - 2.4 6.9 6.2 0.093 11.5 0.1 1.6 2 0 0 2 2 2 0 MreB/Mbl protein Abhydrolase_3 PF07859.13 KXX77525.1 - 5.9e-34 117.8 0.1 8.1e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PNP_UDP_1 PF01048.20 KXX77526.1 - 7.3e-05 22.1 0.0 9.7e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Helicase_C PF00271.31 KXX77527.1 - 4.5e-11 43.1 0.0 8.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXX77527.1 - 0.0031 16.8 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase COesterase PF00135.28 KXX77528.1 - 1.2e-77 262.0 0.0 1.4e-77 261.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX77528.1 - 1.5e-06 28.3 0.1 4.2e-06 26.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold FA_desaturase PF00487.24 KXX77529.1 - 1.4e-32 113.6 22.7 2.1e-32 112.9 22.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXX77529.1 - 1.9e-10 40.7 0.0 4.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.7 KXX77529.1 - 0.014 15.3 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) adh_short PF00106.25 KXX77530.1 - 2.9e-08 33.4 0.0 7.1e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXX77530.1 - 2.5e-05 24.3 0.0 4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXX77530.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 KXX77531.1 - 1.3e-23 84.5 0.0 2.1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX77531.1 - 4.6e-14 52.5 0.0 8.8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 KXX77531.1 - 0.0047 17.4 0.0 0.0082 16.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.12 KXX77531.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 KXX77531.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 KXX77531.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.18 KXX77532.1 - 2e-17 63.1 0.2 3e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX77532.1 - 2.2e-09 37.3 7.7 4.7e-09 36.2 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 KXX77533.1 - 7.2e-91 305.1 0.3 8.3e-91 304.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S41 PF03572.18 KXX77534.1 - 7.4e-09 35.4 0.0 2e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 ketoacyl-synt PF00109.26 KXX77535.1 - 8.4e-63 212.3 3.5 6e-62 209.5 0.1 3.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXX77535.1 - 3.4e-57 194.0 0.0 5.5e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXX77535.1 - 1e-56 191.7 1.3 3.3e-56 190.1 0.1 2.5 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KXX77535.1 - 3.2e-45 155.0 0.1 5.4e-45 154.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX77535.1 - 2.5e-40 137.1 0.1 5.8e-40 136.0 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KXX77535.1 - 2.4e-22 80.4 0.0 4.1e-19 70.0 0.0 3.6 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KXX77535.1 - 1.3e-18 67.5 0.0 3.9e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXX77535.1 - 2.1e-18 66.5 3.4 5.2e-17 62.0 0.1 4.2 4 1 0 4 4 4 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXX77535.1 - 2.3e-16 60.2 1.0 5.2e-11 43.0 0.1 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KXX77535.1 - 4.3e-13 49.1 0.0 1.1e-10 41.3 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXX77535.1 - 4.9e-12 46.4 0.1 6.2e-11 42.9 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX77535.1 - 1.8e-11 44.2 0.0 4.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77535.1 - 3.5e-10 40.4 0.0 1.5e-09 38.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX77535.1 - 3.2e-07 29.9 0.0 6.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXX77535.1 - 1.4e-06 28.1 0.0 4.9e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KXX77535.1 - 3.7e-06 27.2 0.1 1e-05 25.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sacchrp_dh_NADP PF03435.18 KXX77535.1 - 4.6e-05 23.7 1.0 0.00015 22.1 0.1 2.4 3 0 0 3 3 2 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KXX77535.1 - 8.8e-05 22.2 0.2 0.00056 19.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXX77535.1 - 0.00029 20.3 0.6 0.00076 18.9 0.2 1.9 2 0 0 2 2 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 KXX77535.1 - 0.001 18.3 0.2 0.0037 16.4 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX77535.1 - 0.0037 16.7 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PALP PF00291.25 KXX77535.1 - 0.0042 16.5 0.1 0.33 10.3 0.0 2.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 KXX77535.1 - 0.0059 16.1 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_9 PF08003.11 KXX77535.1 - 0.025 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_33 PF10017.9 KXX77535.1 - 0.032 13.4 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_8 PF05148.15 KXX77535.1 - 0.039 13.8 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase 3Beta_HSD PF01073.19 KXX77535.1 - 0.064 12.2 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cupin_2 PF07883.11 KXX77536.1 - 9.6e-10 38.0 0.5 1.6e-09 37.4 0.5 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXX77536.1 - 6.8e-06 25.8 0.1 8.4e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 KXX77536.1 - 0.0099 15.8 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 ChrR Cupin-like domain zf-C2HC5 PF06221.13 KXX77537.1 - 4.5e-23 81.0 6.2 7e-23 80.4 6.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Tropomodulin PF03250.14 KXX77537.1 - 0.0032 17.5 0.4 0.0065 16.5 0.4 1.5 1 0 0 1 1 1 1 Tropomodulin SIR2 PF02146.17 KXX77538.1 - 1.4e-30 106.6 0.0 2.7e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Na_H_Exchanger PF00999.21 KXX77540.1 - 3.1e-29 102.0 34.3 2.4e-28 99.0 34.3 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Fst_toxin PF13955.6 KXX77540.1 - 0.046 13.7 1.3 0.046 13.7 1.3 3.7 3 0 0 3 3 3 0 Toxin Fst, type I toxin-antitoxin system Pro-kuma_activ PF09286.11 KXX77541.1 - 2.5e-31 108.9 0.0 4.1e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXX77541.1 - 2.2e-07 30.4 0.0 3.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Subtilase family p450 PF00067.22 KXX77542.1 - 8.8e-21 74.2 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXX77543.1 - 3e-08 32.9 0.0 4.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.22 KXX77544.1 - 2e-12 47.0 1.4 2.5e-12 46.7 1.4 1.1 1 0 0 1 1 1 1 Subtilase family VWA PF00092.28 KXX77546.1 - 2.8e-16 60.3 0.2 4.6e-16 59.6 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXX77546.1 - 8.7e-14 52.1 0.0 2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXX77546.1 - 0.00014 21.8 0.0 0.0003 20.7 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KXX77546.1 - 0.00018 21.0 0.9 0.011 15.1 0.2 2.1 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein BTB PF00651.31 KXX77547.1 - 2.1e-07 31.1 0.0 3.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Globin PF00042.22 KXX77550.1 - 8.7e-10 39.2 0.0 1.6e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 KXX77550.1 - 1.9e-07 31.7 0.0 4.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXX77550.1 - 1.4e-05 25.3 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXX77550.1 - 0.0027 17.8 0.1 0.063 13.4 0.0 2.6 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KXX77550.1 - 0.0054 16.7 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 Protoglobin Fib_alpha PF08702.10 KXX77550.1 - 0.064 13.4 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APH PF01636.23 KXX77551.1 - 1.4e-06 28.4 0.2 7.7e-06 26.0 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXX77551.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase adh_short_C2 PF13561.6 KXX77553.1 - 6.3e-51 173.2 1.4 8.9e-51 172.7 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX77553.1 - 5.5e-41 140.2 1.8 1.6e-40 138.7 1.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX77553.1 - 7.6e-11 42.2 1.6 1.1e-10 41.7 1.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX77553.1 - 0.0076 15.7 0.2 0.019 14.4 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 KXX77555.1 - 1.5e-06 28.2 9.3 1.5e-06 28.2 9.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX77555.1 - 2.5e-05 23.5 0.0 6.4e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain He_PIG PF05345.12 KXX77555.1 - 0.31 11.3 3.6 0.79 10.0 3.6 1.7 1 0 0 1 1 1 0 Putative Ig domain p450 PF00067.22 KXX77556.1 - 1.9e-24 86.3 0.0 2.5e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ccdc124 PF06244.12 KXX77557.1 - 2.1e-15 57.4 0.3 2.3e-15 57.3 0.3 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 SurA_N PF09312.11 KXX77557.1 - 0.12 12.4 0.2 0.17 12.0 0.2 1.2 1 0 0 1 1 1 0 SurA N-terminal domain DEAD PF00270.29 KXX77558.1 - 7.1e-18 65.0 0.0 2.3e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXX77558.1 - 1.2e-06 28.6 0.0 2.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXX77558.1 - 3.5e-06 27.3 0.0 1.3e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 KXX77558.1 - 0.078 13.6 0.0 0.26 11.9 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain zf-HC5HC2H_2 PF13832.6 KXX77559.1 - 5.8e-21 74.7 1.8 5.8e-21 74.7 1.8 4.2 4 0 0 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.18 KXX77559.1 - 9.9e-18 64.2 0.0 2.4e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KXX77559.1 - 2.3e-16 59.8 2.8 2.3e-16 59.8 2.8 4.8 5 0 0 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 KXX77559.1 - 8.4e-10 38.4 24.6 2e-06 27.6 10.7 6.6 8 0 0 8 8 8 3 PHD-finger PHD_2 PF13831.6 KXX77559.1 - 1.8e-08 33.8 3.2 1.8e-08 33.8 3.2 5.6 7 0 0 7 7 7 2 PHD-finger C1_1 PF00130.22 KXX77559.1 - 0.0039 17.1 1.6 0.0039 17.1 1.6 6.3 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.31 KXX77559.1 - 0.015 15.5 0.0 0.042 14.0 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain C1_2 PF03107.16 KXX77559.1 - 0.027 14.8 0.1 0.027 14.8 0.1 6.7 7 0 0 7 7 7 0 C1 domain ELM2 PF01448.24 KXX77559.1 - 0.14 12.9 2.2 2.4 9.0 0.0 3.5 3 1 0 3 3 3 0 ELM2 domain Ribonuc_L-PSP PF01042.21 KXX77561.1 - 8.5e-10 38.7 0.0 1.2e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Tox-HNH-EHHH PF15657.6 KXX77562.1 - 0.58 10.6 5.2 1.1 9.6 0.1 2.6 2 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins MMR_HSR1 PF01926.23 KXX77563.1 - 5.1e-17 62.0 0.2 4.4e-15 55.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX77563.1 - 2.2e-07 30.5 0.3 1.4e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXX77563.1 - 4.5e-06 26.7 0.0 0.0095 15.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KXX77563.1 - 0.0033 17.5 0.1 0.38 10.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 KXX77563.1 - 0.05 13.2 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 KXX77563.1 - 0.052 12.9 0.1 0.093 12.0 0.1 1.4 1 0 0 1 1 1 0 AIG1 family Ribosomal_L5_C PF00673.21 KXX77564.1 - 4.5e-26 90.8 0.0 7.7e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXX77564.1 - 1.9e-07 31.3 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.10 KXX77565.1 - 1.4e-33 115.6 1.3 1.4e-33 115.6 1.3 2.4 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KXX77565.1 - 1e-06 28.6 0.0 0.0061 16.6 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXX77565.1 - 6.2e-06 26.5 0.2 1.7e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KXX77565.1 - 5.3e-05 23.6 0.4 0.0014 19.0 0.1 2.3 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KXX77565.1 - 8.7e-05 22.5 0.0 0.048 13.9 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat Aconitase_B_N PF11791.8 KXX77565.1 - 0.047 13.8 0.5 1.1 9.3 0.0 2.9 2 1 1 3 3 3 0 Aconitate B N-terminal domain Actin PF00022.19 KXX77566.1 - 2.9e-150 500.4 0.0 1.1e-149 498.5 0.0 1.7 1 1 0 1 1 1 1 Actin SPT_ssu-like PF11779.8 KXX77567.1 - 2.3e-21 75.1 7.0 3e-21 74.8 7.0 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like WD40 PF00400.32 KXX77568.1 - 2.2e-30 104.2 18.8 0.0011 19.7 0.0 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX77568.1 - 2.5e-08 34.1 0.8 1.5 9.2 0.1 6.8 5 3 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Urm1 PF09138.11 KXX77569.1 - 3.5e-35 120.2 0.0 4.1e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KXX77569.1 - 0.065 13.9 0.0 0.077 13.7 0.0 1.2 1 0 0 1 1 1 0 ThiS family RF-1 PF00472.20 KXX77570.1 - 9.4e-25 86.8 2.4 1.7e-24 86.0 2.4 1.3 1 0 0 1 1 1 1 RF-1 domain RRM_1 PF00076.22 KXX77571.1 - 4.3e-34 116.2 0.0 6.9e-16 57.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KXX77571.1 - 0.0041 16.8 0.1 3.6 7.3 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 KXX77571.1 - 0.011 15.4 0.0 0.15 11.7 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXX77571.1 - 0.013 15.7 0.0 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 KXX77571.1 - 0.023 14.8 0.1 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 KXX77571.1 - 0.089 12.9 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif Cas_Cas2CT1978 PF09707.10 KXX77571.1 - 0.21 11.7 0.0 2.5 8.3 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Tom7 PF08038.12 KXX77572.1 - 8.1e-21 73.4 0.3 1.3e-20 72.7 0.3 1.3 1 0 0 1 1 1 1 TOM7 family Aminotran_1_2 PF00155.21 KXX77573.1 - 8.8e-11 41.6 0.0 1.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II LTV PF04180.14 KXX77574.1 - 1.4e-126 423.3 7.6 1.6e-126 423.1 7.6 1.0 1 0 0 1 1 1 1 Low temperature viability protein Mito_carr PF00153.27 KXX77575.1 - 5.2e-54 180.2 3.5 1.7e-18 66.3 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 KXX77576.1 - 6.4e-20 70.4 22.9 6.5e-07 29.5 0.5 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX77576.1 - 2.3e-14 52.8 17.8 7.8e-05 23.2 0.2 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXX77576.1 - 4.7e-12 45.8 28.6 8.4e-08 32.3 0.7 4.9 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXX77576.1 - 1.1e-08 34.9 13.6 0.00041 20.3 0.6 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXX77576.1 - 0.0012 19.1 6.6 0.095 13.0 1.5 2.7 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2HE PF16278.5 KXX77576.1 - 0.0019 18.6 8.7 0.057 13.9 0.6 3.0 2 1 1 3 3 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KXX77576.1 - 0.01 15.6 0.6 3.6 7.4 0.0 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KXX77576.1 - 0.011 15.9 4.1 0.37 10.9 0.2 2.4 2 1 0 2 2 2 0 Aberrant zinc-finger SUIM_assoc PF16619.5 KXX77576.1 - 0.032 14.3 2.3 0.032 14.3 2.3 2.2 2 0 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 zf_UBZ PF18439.1 KXX77576.1 - 0.078 12.6 0.7 1.4 8.5 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KXX77576.1 - 0.86 9.8 6.4 3.4 7.9 4.7 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 KXX77576.1 - 0.92 9.6 14.3 0.8 9.8 1.4 3.6 1 1 3 4 4 4 0 BED zinc finger zf-met PF12874.7 KXX77576.1 - 1.5 9.3 9.0 2.4 8.7 0.0 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type IQCJ-SCHIP1 PF15157.6 KXX77576.1 - 2.1 8.2 4.9 2.1 8.2 2.1 2.0 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif zf-LYAR PF08790.11 KXX77576.1 - 3.9 7.5 10.5 7.2 6.6 0.1 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 KXX77576.1 - 5.8 7.3 10.8 5.6 7.4 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXX77576.1 - 9.6 6.9 8.9 22 5.8 0.6 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain MIF4G_like PF09088.11 KXX77577.1 - 2e-94 314.8 0.2 3.1e-94 314.1 0.2 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KXX77577.1 - 1.5e-72 244.3 0.0 2.6e-72 243.5 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MscS_TM PF12794.7 KXX77577.1 - 1 8.1 3.3 2 7.2 3.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FMO-like PF00743.19 KXX77578.1 - 4.2e-46 157.5 0.0 1.5e-25 89.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXX77578.1 - 4.6e-14 52.4 0.5 2.1e-07 30.5 0.4 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX77578.1 - 4.3e-13 49.1 0.0 4.2e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX77578.1 - 9.9e-12 45.1 0.0 5.7e-11 42.6 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KXX77578.1 - 4.7e-08 33.0 0.0 0.0017 18.0 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXX77578.1 - 6.9e-08 32.0 1.0 2.6e-06 26.8 0.1 2.7 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXX77578.1 - 3.5e-07 30.4 0.0 1.4e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXX77578.1 - 5.3e-07 29.1 0.1 2.8e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KXX77578.1 - 0.00027 20.3 0.0 0.092 12.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXX77578.1 - 0.0015 17.3 1.1 0.03 13.0 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 KXX77578.1 - 0.0045 17.5 0.7 1.4 9.5 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXX77578.1 - 0.036 12.9 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 MCRA family FAD_binding_2 PF00890.24 KXX77578.1 - 0.07 12.2 0.1 0.65 9.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 KXX77578.1 - 0.098 12.7 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KXX77578.1 - 0.12 11.9 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 KXX77578.1 - 0.16 11.0 0.2 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXX77578.1 - 0.17 11.1 0.0 0.42 9.8 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain POT1 PF02765.17 KXX77579.1 - 9.7e-09 35.2 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Malic_M PF03949.15 KXX77580.1 - 2.9e-93 311.8 0.0 4.2e-93 311.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXX77580.1 - 1.9e-71 239.7 0.0 3.9e-71 238.6 0.0 1.6 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain LRR_6 PF13516.6 KXX77581.1 - 2.9e-06 26.9 0.8 0.013 15.5 0.0 5.1 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 KXX77581.1 - 6.7e-05 23.2 2.1 4.1 8.0 0.0 5.8 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXX77581.1 - 0.00012 21.8 0.1 0.11 12.2 0.0 4.0 5 0 0 5 5 5 1 Leucine rich repeat GATA PF00320.27 KXX77581.1 - 0.00047 19.7 3.9 0.0014 18.2 1.2 2.4 2 0 0 2 2 2 1 GATA zinc finger zf-ribbon_3 PF13248.6 KXX77581.1 - 0.16 11.5 2.2 2 8.0 0.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain LRR_1 PF00560.33 KXX77581.1 - 0.96 10.2 3.6 70 4.6 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich Repeat SNF2_N PF00176.23 KXX77582.1 - 1.7e-48 165.1 0.0 3.2e-47 161.0 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX77582.1 - 4.2e-16 59.3 0.0 2.9e-15 56.5 0.0 2.3 3 0 0 3 3 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KXX77582.1 - 4.8e-08 32.7 9.4 4.8e-08 32.7 9.4 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXX77582.1 - 1.2e-07 31.9 0.7 2.9e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KXX77582.1 - 2.8e-05 23.9 8.0 2.8e-05 23.9 8.0 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX77582.1 - 5.5e-05 22.9 7.7 5.5e-05 22.9 7.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX77582.1 - 0.00018 21.8 9.2 0.00018 21.8 9.2 2.8 2 0 0 2 2 1 1 Ring finger domain DEAD PF00270.29 KXX77582.1 - 0.00044 20.1 0.1 0.00097 18.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 KXX77582.1 - 0.013 15.5 8.6 0.013 15.5 8.6 2.5 2 0 0 2 2 2 0 zinc-RING finger domain AAA_34 PF13872.6 KXX77582.1 - 0.014 14.3 0.0 0.036 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-Nse PF11789.8 KXX77582.1 - 0.25 11.2 4.1 0.74 9.7 4.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.6 KXX77582.1 - 2.8 8.1 14.2 1.5 8.9 3.8 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain DUF1793 PF08760.11 KXX77583.1 - 5.6e-77 257.9 0.6 1.5e-76 256.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KXX77583.1 - 8.8e-67 224.1 0.9 8.8e-52 175.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXX77583.1 - 4.7e-42 144.3 0.4 7.6e-42 143.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KXX77583.1 - 0.001 18.5 0.2 0.0023 17.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) RRM_1 PF00076.22 KXX77584.1 - 6.5e-19 67.5 0.0 9.9e-19 66.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXX77584.1 - 0.00063 19.3 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.27 KXX77585.1 - 1.4e-47 161.6 0.0 2.7e-26 92.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXX77585.1 - 9.8e-39 133.6 36.5 3.2e-22 79.5 3.4 4.1 4 0 0 4 4 4 4 ABC transporter transmembrane region AAA_16 PF13191.6 KXX77585.1 - 1.7e-05 25.3 0.0 0.12 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KXX77585.1 - 3.6e-05 23.8 1.4 0.053 13.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KXX77585.1 - 9e-05 21.8 0.1 0.0083 15.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 KXX77585.1 - 0.00013 21.5 0.3 5.1 6.5 0.0 3.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXX77585.1 - 0.00016 21.6 0.4 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXX77585.1 - 0.0004 21.0 0.5 0.84 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXX77585.1 - 0.00056 19.6 1.1 1.1 9.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KXX77585.1 - 0.0018 18.0 2.7 0.49 10.1 0.2 2.8 3 0 0 3 3 3 2 AAA domain MeaB PF03308.16 KXX77585.1 - 0.0023 17.0 1.5 1.3 7.9 0.1 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 KXX77585.1 - 0.0038 17.1 1.3 1.9 8.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXX77585.1 - 0.0079 16.5 0.8 5.8 7.2 0.1 3.2 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 KXX77585.1 - 0.012 14.5 1.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 KXX77585.1 - 0.026 14.6 4.3 0.16 12.0 0.6 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 KXX77585.1 - 0.029 14.6 1.3 0.13 12.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KXX77585.1 - 0.04 13.8 0.8 0.66 9.9 0.0 2.9 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 KXX77585.1 - 0.041 13.6 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 KXX77585.1 - 0.042 14.1 0.2 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KXX77585.1 - 0.053 13.2 0.3 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KXX77585.1 - 0.074 12.6 0.3 3.4 7.1 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 KXX77585.1 - 0.26 11.0 0.1 5.9 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KXX77585.1 - 0.29 11.7 1.0 6.4 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXX77585.1 - 0.33 10.7 1.7 14 5.3 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KXX77585.1 - 0.44 10.6 6.6 0.82 9.7 0.1 2.9 3 0 0 3 3 3 0 Dynamin family cobW PF02492.19 KXX77585.1 - 1 9.0 3.0 1.7 8.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.32 KXX77586.1 - 2.4e-23 82.0 1.0 2e-08 34.7 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX77586.1 - 1.1e-11 44.8 0.0 0.00021 21.5 0.0 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXX77586.1 - 2.5e-08 33.6 1.2 0.37 10.8 0.0 3.6 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXX77586.1 - 1.5e-06 27.5 0.5 0.049 12.6 0.1 2.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KXX77586.1 - 0.0016 18.0 0.1 25 4.6 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF4784 PF16023.5 KXX77586.1 - 0.019 14.0 0.0 1.6 7.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4784) Nup160 PF11715.8 KXX77586.1 - 0.021 13.5 0.0 2.4 6.7 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KXX77586.1 - 0.03 13.9 1.0 0.12 11.9 0.5 2.1 2 1 0 2 2 2 0 PQQ-like domain Methyltransf_3 PF01596.17 KXX77586.1 - 0.14 11.3 0.1 36 3.4 0.0 3.0 1 1 2 3 3 3 0 O-methyltransferase DUF1275 PF06912.11 KXX77586.1 - 0.16 11.9 2.1 6 6.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) Ret2_MD PF18528.1 KXX77586.1 - 0.18 12.2 0.0 94 3.5 0.0 3.1 1 1 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF1079 PF06435.11 KXX77586.1 - 0.22 11.8 1.3 26 5.2 0.1 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) Ost4 PF10215.9 KXX77587.1 - 1.9e-19 69.1 0.6 2.3e-19 68.9 0.6 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase Glutaredoxin PF00462.24 KXX77587.1 - 0.061 13.5 0.0 0.069 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin CS PF04969.16 KXX77588.1 - 2.8e-06 28.3 0.0 4.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.22 KXX77589.1 - 2.8e-15 55.9 0.0 5.3e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXX77589.1 - 0.00019 21.9 1.8 0.00047 20.7 1.8 1.7 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KXX77589.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KXX77589.1 - 0.17 12.1 0.0 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ank_2 PF12796.7 KXX77590.1 - 3.3e-20 72.4 0.3 3.3e-10 40.4 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77590.1 - 4.6e-16 59.0 0.2 7.8e-07 29.5 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX77590.1 - 7.3e-14 51.7 6.0 3.8e-07 30.3 0.3 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77590.1 - 1.1e-13 50.0 5.5 0.015 15.8 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KXX77590.1 - 9.1e-09 35.4 6.2 0.018 15.5 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat Retinal PF15449.6 KXX77591.1 - 0.18 9.6 14.5 0.21 9.3 14.5 1.1 1 0 0 1 1 1 0 Retinal protein adh_short PF00106.25 KXX77592.1 - 1.4e-24 86.6 0.0 1.9e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX77592.1 - 1.6e-20 73.6 0.0 2.1e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX77592.1 - 3.2e-05 23.9 0.0 4.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 KR domain Pkinase PF00069.25 KXX77593.1 - 1e-75 254.5 0.0 1.4e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77593.1 - 3.7e-31 108.4 0.0 1.7e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXX77593.1 - 6.1e-07 29.0 0.1 0.55 9.5 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KXX77593.1 - 0.015 14.1 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXX77593.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX77593.1 - 0.039 13.9 0.0 0.92 9.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family SLAC1 PF03595.17 KXX77594.1 - 7.7e-73 245.6 38.4 9.7e-73 245.2 38.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2678 PF10856.8 KXX77594.1 - 1.1 9.2 6.4 1.5 8.8 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) RNA_pol_Rpb4 PF03874.16 KXX77595.1 - 1.8e-24 86.4 0.3 2.1e-24 86.2 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 MMS19_C PF12460.8 KXX77595.1 - 0.0017 17.5 0.0 0.0019 17.4 0.0 1.0 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal DUF3775 PF12616.8 KXX77595.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) DUF5343 PF17278.2 KXX77595.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5343) Pribosyl_synth PF14572.6 KXX77596.1 - 4.9e-40 137.5 1.9 8e-35 120.5 0.4 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXX77596.1 - 1e-30 106.1 0.0 5.8e-30 103.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXX77596.1 - 4.6e-16 58.7 0.2 7.4e-16 58.1 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXX77596.1 - 0.012 15.1 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PseudoU_synth_1 PF01416.20 KXX77597.1 - 7.4e-34 116.5 0.0 3.8e-33 114.2 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridine synthase Ras PF00071.22 KXX77598.1 - 1.2e-18 67.2 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX77598.1 - 7.6e-07 29.4 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX77598.1 - 0.00056 19.4 0.0 0.0048 16.4 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXX77598.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Snf7 PF03357.21 KXX77600.1 - 4.5e-19 68.7 13.4 4.5e-19 68.7 13.4 2.1 1 1 1 2 2 2 1 Snf7 Tnp_P_element PF12017.8 KXX77600.1 - 4.1e-05 23.1 0.5 5.7e-05 22.7 0.5 1.2 1 0 0 1 1 1 1 Transposase protein CsbD PF05532.12 KXX77600.1 - 0.06 13.3 1.0 1.1 9.2 0.6 2.5 2 0 0 2 2 2 0 CsbD-like NAD_binding_5 PF07994.12 KXX77600.1 - 0.71 9.2 3.7 0.4 10.0 0.5 1.9 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase Glyco_hydro_62 PF03664.13 KXX77601.1 - 0.32 10.3 2.6 0.44 9.8 2.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 RasGEF PF00617.19 KXX77602.1 - 2.7e-43 148.2 0.0 4.1e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXX77602.1 - 3.2e-11 43.4 0.0 6.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif AAA_16 PF13191.6 KXX77602.1 - 9.3e-05 22.9 0.1 0.00071 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 KXX77602.1 - 0.0025 17.4 0.0 0.081 12.5 0.0 2.8 2 1 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 KXX77602.1 - 0.0086 16.0 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KXX77602.1 - 0.038 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXX77602.1 - 0.045 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KXX77602.1 - 0.051 14.1 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXX77602.1 - 0.059 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXX77602.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KXX77602.1 - 0.065 12.6 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.13 KXX77602.1 - 0.099 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 KXX77602.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KXX77602.1 - 0.15 11.9 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KXX77602.1 - 0.17 11.7 0.0 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX77602.1 - 0.19 12.0 0.1 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KXX77602.1 - 0.2 11.3 0.1 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase PIG-H PF10181.9 KXX77603.1 - 8.8e-27 92.8 0.2 1.3e-26 92.2 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DFRP_C PF16543.5 KXX77604.1 - 3.7e-26 91.4 7.0 3.7e-26 91.4 7.0 3.6 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KXX77604.1 - 2.8e-06 28.0 3.4 2.8e-06 28.0 3.4 3.6 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KXX77604.1 - 9.1e-06 25.5 1.0 9.1e-06 25.5 1.0 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXX77604.1 - 2e-05 24.3 11.3 0.00049 19.8 2.2 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXX77604.1 - 0.00013 21.9 6.7 0.00013 21.9 6.7 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 KXX77604.1 - 0.00055 20.1 1.5 0.11 12.8 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXX77604.1 - 0.035 14.6 16.6 0.35 11.4 6.7 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Tyrosinase PF00264.20 KXX77605.1 - 7.1e-45 154.0 2.2 1e-44 153.5 2.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXX77605.1 - 0.00019 22.1 0.0 0.00076 20.1 0.0 2.0 1 1 0 1 1 1 1 Tyosinase C-terminal domain Nfu_N PF08712.11 KXX77606.1 - 8.8e-29 99.4 0.1 2.3e-28 98.1 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KXX77606.1 - 7.4e-27 93.3 0.0 1.2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.12 KXX77607.1 - 1e-28 99.4 1.6 1.8e-28 98.7 1.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RNA_pol_Rpb2_4 PF04566.13 KXX77608.1 - 0.24 11.7 0.6 1.3 9.4 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 zf-HIT PF04438.16 KXX77609.1 - 4.9e-12 45.5 10.4 8.1e-12 44.8 10.4 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KXX77609.1 - 9.2e-05 22.5 7.1 0.00014 21.9 7.1 1.3 1 0 0 1 1 1 1 MYND finger YL1_C PF08265.11 KXX77609.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-B_box PF00643.24 KXX77609.1 - 0.55 10.4 5.2 0.86 9.8 5.2 1.3 1 0 0 1 1 1 0 B-box zinc finger Lipase_3 PF01764.25 KXX77610.1 - 3.6e-21 75.5 0.0 6.1e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Gate PF07670.14 KXX77610.1 - 0.032 14.5 0.1 0.051 13.8 0.1 1.3 1 0 0 1 1 1 0 Nucleoside recognition DUF2974 PF11187.8 KXX77610.1 - 0.13 11.7 0.1 7.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF89 PF01937.19 KXX77611.1 - 1.1e-10 41.1 0.1 1.2e-10 40.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 ABC_tran PF00005.27 KXX77612.1 - 3.5e-46 157.1 0.0 1.1e-22 81.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXX77612.1 - 5.2e-23 80.9 1.5 5.2e-23 80.9 1.5 3.4 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 KXX77612.1 - 1.6e-18 67.5 0.6 7.6e-05 22.7 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX77612.1 - 1.5e-11 44.2 0.1 0.0056 16.1 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXX77612.1 - 1.2e-08 34.6 0.1 0.0032 17.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXX77612.1 - 1.8e-08 35.1 3.7 0.021 15.3 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXX77612.1 - 1e-06 29.3 0.0 0.0051 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KXX77612.1 - 1.1e-06 28.6 0.1 0.034 13.9 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXX77612.1 - 5.2e-06 26.5 0.9 0.01 15.8 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXX77612.1 - 6.8e-06 26.2 0.0 0.025 14.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KXX77612.1 - 1e-05 26.1 0.1 0.26 11.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KXX77612.1 - 1.3e-05 25.5 0.0 0.064 13.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KXX77612.1 - 5e-05 23.7 0.0 0.28 11.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX77612.1 - 7.7e-05 22.9 0.1 0.68 10.1 0.1 3.9 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 KXX77612.1 - 9.5e-05 22.4 0.1 0.2 11.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KXX77612.1 - 0.0001 22.6 0.0 0.045 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXX77612.1 - 0.00014 21.9 0.2 0.55 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXX77612.1 - 0.00019 21.8 2.2 1.9 8.9 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_14 PF13173.6 KXX77612.1 - 0.00062 19.8 0.0 1.6 8.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXX77612.1 - 0.00095 18.9 0.5 2 8.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.23 KXX77612.1 - 0.0016 18.6 1.1 2.3 8.3 0.0 3.6 3 1 1 4 4 4 1 Dynamin family AAA_27 PF13514.6 KXX77612.1 - 0.0016 18.0 0.0 0.41 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KXX77612.1 - 0.0022 18.2 0.1 3.3 8.0 0.1 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KXX77612.1 - 0.0031 17.2 0.8 2 8.1 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KXX77612.1 - 0.0033 17.0 0.0 0.49 9.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain DUF2813 PF11398.8 KXX77612.1 - 0.0054 16.0 0.8 0.79 8.9 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) NB-ARC PF00931.22 KXX77612.1 - 0.0098 15.1 0.2 6.3 5.9 0.0 3.1 4 0 0 4 4 4 0 NB-ARC domain AAA_17 PF13207.6 KXX77612.1 - 0.01 16.3 0.0 2.6 8.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXX77612.1 - 0.037 14.0 0.3 4.7 7.0 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 KXX77612.1 - 0.038 13.1 0.1 4.1 6.4 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 KXX77612.1 - 0.041 13.4 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region CdiI_N PF18228.1 KXX77612.1 - 0.052 13.4 0.0 8 6.3 0.0 2.8 2 1 1 3 3 2 0 CdiI N-terminal domain DUF815 PF05673.13 KXX77612.1 - 0.057 12.6 0.1 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MukB PF04310.12 KXX77612.1 - 0.076 12.8 0.6 17 5.2 0.1 3.3 2 1 1 3 3 3 0 MukB N-terminal NTPase_1 PF03266.15 KXX77612.1 - 0.1 12.5 2.7 2.3 8.1 0.2 2.9 3 0 0 3 3 3 0 NTPase DAP3 PF10236.9 KXX77612.1 - 0.12 11.5 0.8 6.9 5.7 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.18 KXX77612.1 - 0.12 11.9 0.2 9.3 5.8 0.0 2.7 3 0 0 3 3 2 0 Ferrous iron transport protein B DUF87 PF01935.17 KXX77612.1 - 0.18 11.9 2.0 16 5.5 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain TsaE PF02367.17 KXX77612.1 - 0.23 11.5 1.6 31 4.6 0.0 3.3 3 1 1 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 KXX77612.1 - 9.4 3.6 7.1 0.43 8.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) SNF2_N PF00176.23 KXX77613.1 - 2.7e-65 220.4 1.0 5e-65 219.5 1.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KXX77613.1 - 1e-48 165.1 16.4 1e-48 165.1 16.4 5.3 4 2 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 KXX77613.1 - 1.4e-19 70.5 0.0 3.8e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX77613.1 - 2.2e-07 31.1 0.0 1.2e-06 28.7 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXX77613.1 - 0.0019 17.4 0.0 0.038 13.1 0.0 2.7 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 baeRF_family12 PF18856.1 KXX77613.1 - 0.038 14.6 0.1 0.038 14.6 0.1 4.6 4 1 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 12 Fe_hyd_lg_C PF02906.14 KXX77613.1 - 0.54 9.9 6.6 0.11 12.1 1.8 2.2 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Promethin PF16015.5 KXX77614.1 - 1.3e-31 108.6 15.6 1.7e-31 108.3 15.6 1.1 1 0 0 1 1 1 1 Promethin DUF1700 PF08006.11 KXX77614.1 - 0.69 9.4 3.1 0.91 9.0 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4234 PF14018.6 KXX77614.1 - 5.6 7.2 11.0 11 6.3 10.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) GFO_IDH_MocA PF01408.22 KXX77615.1 - 4.4e-24 85.6 0.0 6.8e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXX77615.1 - 8.3e-13 48.4 0.1 1.6e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KXX77615.1 - 3.1e-05 24.6 0.0 6.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KXX77615.1 - 0.0051 17.2 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 KXX77615.1 - 0.081 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Sacchrp_dh_NADP PF03435.18 KXX77615.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AAA_33 PF13671.6 KXX77615.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 KXX77616.1 - 1.2e-16 60.7 0.0 2.2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX77616.1 - 1.3e-08 34.7 0.0 2.2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX77616.1 - 7.2e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 KR domain GHMP_kinases_C PF08544.13 KXX77616.1 - 0.032 14.6 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Glyco_hydro_72 PF03198.14 KXX77617.1 - 8.1e-123 409.7 3.1 1e-122 409.4 3.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXX77617.1 - 3.4e-22 78.9 4.0 1.1e-21 77.3 4.0 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 KXX77617.1 - 0.00099 18.3 1.1 0.0047 16.1 1.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Alpha_GJ PF03229.13 KXX77617.1 - 0.074 13.6 7.2 0.2 12.2 7.2 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J Lipoxygenase PF00305.19 KXX77619.1 - 2.1e-48 165.3 4.6 8.9e-48 163.2 4.6 1.8 1 1 0 1 1 1 1 Lipoxygenase LIDHydrolase PF10230.9 KXX77620.1 - 2.6e-64 217.4 0.0 3e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KXX77620.1 - 2.1e-05 25.3 0.4 3.1e-05 24.7 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXX77620.1 - 0.017 14.9 0.1 0.031 14.0 0.1 1.4 1 1 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KXX77620.1 - 0.044 13.0 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FHA PF00498.26 KXX77620.1 - 0.13 12.6 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 FHA domain Abhydrolase_1 PF00561.20 KXX77620.1 - 0.14 11.8 0.1 0.43 10.2 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_10 PF00331.20 KXX77622.1 - 1.1e-90 304.0 0.0 1.2e-90 303.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 T6SS_TssG PF06996.11 KXX77622.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion, TssG Fungal_trans_2 PF11951.8 KXX77623.1 - 4.6e-05 22.4 0.1 5.8e-05 22.1 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain CVNH PF08881.10 KXX77624.1 - 1.6e-12 48.0 0.1 5.7e-12 46.2 0.1 1.7 1 1 0 1 1 1 1 CVNH domain Spherulin4 PF12138.8 KXX77625.1 - 5.9e-12 45.7 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Spherulation-specific family 4 RAI16-like PF10257.9 KXX77626.1 - 3.6e-74 249.8 2.4 5.5e-74 249.2 2.4 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein SesA PF17107.5 KXX77627.1 - 0.022 15.0 0.1 0.043 14.0 0.1 1.6 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FAD_binding_4 PF01565.23 KXX77628.1 - 5.1e-23 81.3 5.8 8.4e-23 80.6 5.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX77628.1 - 8.5e-11 41.8 0.0 1.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Augurin PF15187.6 KXX77628.1 - 0.18 12.0 2.0 0.16 12.1 0.5 1.7 2 0 0 2 2 2 0 Oesophageal cancer-related gene 4 GFA PF04828.14 KXX77629.1 - 1.5e-17 63.7 6.1 4.7e-08 33.3 0.2 3.8 3 1 1 4 4 4 3 Glutathione-dependent formaldehyde-activating enzyme Ytp1 PF10355.9 KXX77630.1 - 6e-68 229.0 21.8 2.4e-67 227.1 21.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXX77630.1 - 1.7e-33 114.5 0.9 1.7e-33 114.5 0.9 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KXX77630.1 - 0.0065 16.6 5.3 0.0065 16.6 5.3 3.5 5 1 0 5 5 5 1 Eukaryotic cytochrome b561 DUF4149 PF13664.6 KXX77630.1 - 1.2 9.5 17.3 0.51 10.7 0.3 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4149) Peptidase_M20 PF01546.28 KXX77631.1 - 4.4e-07 29.8 0.6 9.1e-07 28.8 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXX77631.1 - 7.1e-06 25.9 0.0 1.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Oxidored_FMN PF00724.20 KXX77632.1 - 6e-48 163.8 0.0 3.9e-41 141.4 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KXX77632.1 - 0.015 14.4 0.1 0.071 12.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) AP_endonuc_2 PF01261.24 KXX77632.1 - 0.079 12.4 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Arylesterase PF01731.20 KXX77633.1 - 0.021 15.0 0.0 0.17 12.1 0.0 2.5 2 1 0 2 2 2 0 Arylesterase Glyco_hydro_62 PF03664.13 KXX77634.1 - 1.5e-149 496.7 10.3 1.8e-149 496.5 10.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 KXX77634.1 - 0.0011 18.9 5.5 0.0024 17.8 5.5 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3176 PF11374.8 KXX77635.1 - 3.2e-29 101.3 0.4 7.4e-29 100.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) NTP_transf_3 PF12804.7 KXX77636.1 - 2.2e-29 102.9 1.0 1.1e-28 100.7 1.0 1.9 1 1 0 1 1 1 1 MobA-like NTP transferase domain Abhydrolase_6 PF12697.7 KXX77637.1 - 2.6e-19 70.7 1.6 3e-19 70.5 1.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX77637.1 - 0.00014 21.2 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXX77637.1 - 0.045 13.5 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 KXX77637.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CMAS PF02353.20 KXX77638.1 - 3.2e-62 210.3 0.1 4.1e-62 210.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXX77638.1 - 3e-11 43.5 0.0 5.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77638.1 - 4.6e-09 36.8 0.0 1e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77638.1 - 7.5e-08 33.0 0.0 1.4e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77638.1 - 0.00019 22.1 0.0 0.00038 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX77638.1 - 0.034 13.9 0.2 0.12 12.2 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KXX77638.1 - 0.047 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KXX77638.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXX77638.1 - 0.091 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MoeA_N PF03453.17 KXX77639.1 - 1.5e-30 106.0 0.1 2.1e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KXX77639.1 - 6.6e-26 90.7 0.0 9.6e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KXX77639.1 - 0.0072 16.5 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DMRL_synthase PF00885.19 KXX77639.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase He_PIG_assoc PF10632.9 KXX77639.1 - 0.064 12.9 0.1 15 5.4 0.0 2.6 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Molybdopterin PF00384.22 KXX77641.1 - 7.6e-70 236.0 0.0 9.7e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KXX77641.1 - 3.2e-27 94.7 0.0 6.5e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 KXX77641.1 - 1.1e-10 41.3 1.5 1.1e-10 41.3 1.5 1.8 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Zn_clus PF00172.18 KXX77642.1 - 0.13 12.4 5.8 0.28 11.3 5.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX77642.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Dickkopf_N PF04706.12 KXX77642.1 - 3.2 8.3 5.2 7.2 7.2 5.2 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region His_Phos_1 PF00300.22 KXX77643.1 - 2.2e-09 37.3 0.0 2.4e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pox_M2 PF04887.12 KXX77644.1 - 0.14 11.7 0.1 0.14 11.7 0.1 1.5 2 0 0 2 2 2 0 Poxvirus M2 protein DUF4173 PF13777.6 KXX77644.1 - 0.84 9.0 10.3 0.64 9.4 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) CDV3 PF15359.6 KXX77645.1 - 0.23 12.0 0.1 0.39 11.2 0.1 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 DUF1053 PF06327.14 KXX77646.1 - 0.12 13.0 3.1 0.88 10.2 3.7 2.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) Peptidase_C37 PF05416.12 KXX77646.1 - 1 7.8 5.2 1.5 7.2 5.2 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase YqzE PF14038.6 KXX77646.1 - 9.5 6.3 6.4 48 4.1 0.4 2.8 2 0 0 2 2 2 0 YqzE-like protein DUF4360 PF14273.6 KXX77648.1 - 1.4e-07 31.6 0.0 1.7e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Cadherin_5 PF17892.1 KXX77648.1 - 0.053 13.5 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 Cadherin-like domain SGL PF08450.12 KXX77651.1 - 2.9e-05 23.8 0.0 0.0024 17.5 0.0 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KXX77651.1 - 0.00061 19.7 0.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Toxin_22 PF08092.11 KXX77651.1 - 0.12 12.4 0.2 0.27 11.3 0.2 1.6 1 0 0 1 1 1 0 Magi peptide toxin family GMC_oxred_N PF00732.19 KXX77652.1 - 2.6e-45 155.1 0.0 3.6e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX77652.1 - 1.4e-29 103.5 0.0 4.8e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 KXX77652.1 - 0.0085 15.4 0.0 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXX77652.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX77652.1 - 0.066 12.3 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXX77652.1 - 0.077 12.1 0.0 8.3 5.4 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KXX77652.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase PG_binding_1 PF01471.18 KXX77654.1 - 9.8e-10 38.5 0.3 4.2e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 KXX77654.1 - 9.2e-06 25.8 0.0 0.074 13.3 0.0 2.3 1 1 1 2 2 2 2 Predicted Peptidoglycan domain adh_short PF00106.25 KXX77656.1 - 2e-20 73.1 0.1 3.2e-19 69.2 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX77656.1 - 3.7e-14 52.9 0.1 2.5e-13 50.1 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX77656.1 - 0.0065 16.4 0.2 0.012 15.5 0.1 1.6 2 0 0 2 2 2 1 KR domain PP28 PF10252.9 KXX77656.1 - 0.085 13.3 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DUF1993 PF09351.10 KXX77657.1 - 2.8e-49 167.3 0.0 3.2e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF1479 PF07350.12 KXX77658.1 - 4.4e-158 526.4 0.0 5.1e-158 526.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KXX77658.1 - 0.0013 19.0 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) HA2 PF04408.23 KXX77659.1 - 1.2e-17 64.1 0.1 3.1e-17 62.8 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXX77659.1 - 2.8e-15 56.4 0.0 6.5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXX77659.1 - 3.1e-05 24.3 0.0 0.00043 20.6 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXX77659.1 - 0.0014 18.9 0.1 0.0049 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KXX77659.1 - 0.0043 16.8 0.3 0.023 14.5 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KXX77659.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXX77659.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXX77659.1 - 0.055 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXX77659.1 - 0.056 13.9 0.1 0.15 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXX77659.1 - 0.14 11.5 0.0 0.44 9.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mid2 PF04478.12 KXX77660.1 - 0.073 12.9 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Snf7 PF03357.21 KXX77661.1 - 7.5e-35 120.1 6.5 9e-35 119.8 6.5 1.1 1 0 0 1 1 1 1 Snf7 DUF2293 PF10056.9 KXX77662.1 - 3e-33 113.9 0.0 9.3e-33 112.3 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DNA_pol_phi PF04931.13 KXX77662.1 - 0.92 7.5 3.7 1.3 7.0 3.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 KXX77663.1 - 2.5e-30 104.9 1.0 5.2e-11 43.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77663.1 - 1.1e-25 89.6 4.4 3.3e-08 33.9 0.0 6.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) SPX PF03105.19 KXX77663.1 - 4.1e-19 69.8 17.8 6.6e-10 39.5 2.3 3.1 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 KXX77663.1 - 1.8e-18 66.4 7.8 3.7e-05 23.9 0.1 6.9 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77663.1 - 5.8e-17 60.0 6.0 0.00083 19.6 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KXX77663.1 - 2.2e-10 40.5 16.2 0.013 16.0 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeat GDPD PF03009.17 KXX77663.1 - 3.1e-05 23.8 0.0 0.0012 18.6 0.0 2.7 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.6 KXX77663.1 - 0.11 12.1 1.0 1.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Ribosome-assembly protein 3 CUE PF02845.16 KXX77664.1 - 9.5e-13 47.6 0.0 1.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain Glyoxalase PF00903.25 KXX77665.1 - 3.9e-21 75.6 0.1 1e-13 51.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXX77665.1 - 2.4e-10 40.7 0.0 7.6e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXX77665.1 - 0.00011 22.4 0.0 0.097 12.8 0.0 2.9 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KXX77665.1 - 0.0025 18.0 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Enterotoxin_a PF01375.17 KXX77665.1 - 0.006 16.2 0.6 0.0099 15.5 0.6 1.3 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain TPR_17 PF13431.6 KXX77666.1 - 0.088 13.2 0.2 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NCE101 PF11654.8 KXX77667.1 - 1.9e-12 46.6 0.0 2.3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 Ribosomal_L27e PF01777.18 KXX77668.1 - 4.1e-38 129.6 5.2 5.5e-38 129.2 5.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KXX77668.1 - 0.016 15.2 0.4 0.045 13.7 0.1 1.9 2 0 0 2 2 2 0 KOW motif TPT PF03151.16 KXX77669.1 - 1.5e-27 96.8 26.8 1.8e-27 96.5 26.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXX77669.1 - 0.14 12.3 43.5 0.21 11.8 17.7 2.5 3 0 0 3 3 3 0 EamA-like transporter family UAA PF08449.11 KXX77669.1 - 0.74 9.0 27.3 2.3 7.3 27.3 1.7 1 1 0 1 1 1 0 UAA transporter family Amino_oxidase PF01593.24 KXX77670.1 - 1.9e-08 34.0 0.0 3.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX77670.1 - 2.5e-08 34.1 0.1 5.5e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX77670.1 - 0.0014 17.9 0.0 0.095 11.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX77670.1 - 0.0094 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX77670.1 - 0.042 13.4 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXX77670.1 - 0.052 12.8 0.5 0.096 11.9 0.1 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KXX77670.1 - 0.053 12.2 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KXX77670.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KXX77670.1 - 0.17 10.9 0.2 0.39 9.7 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HATPase_c PF02518.26 KXX77671.1 - 1e-29 103.3 0.2 3.3e-29 101.7 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXX77671.1 - 2.4e-21 76.0 0.1 9.4e-21 74.1 0.1 2.1 2 0 0 2 2 1 1 Response regulator receiver domain HisKA PF00512.25 KXX77671.1 - 5.5e-18 64.8 2.6 6.3e-18 64.6 0.5 2.4 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KXX77671.1 - 9.8e-16 58.6 1.4 5.9e-15 56.1 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.6 KXX77671.1 - 2.9e-11 43.8 0.0 9e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KXX77671.1 - 3.9e-07 29.7 0.0 9.6e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 KXX77671.1 - 4.8e-06 27.2 0.1 3.4e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 KXX77671.1 - 0.00016 21.5 0.0 0.0004 20.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_MalT PF17874.1 KXX77671.1 - 0.0018 17.8 3.2 0.09 12.1 0.7 2.7 2 0 0 2 2 2 1 MalT-like TPR region Pkinase_Tyr PF07714.17 KXX77671.1 - 0.0025 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.12 KXX77671.1 - 0.007 16.3 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KXX77671.1 - 0.016 14.4 0.0 0.051 12.8 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain TPR_12 PF13424.6 KXX77671.1 - 0.99 9.7 8.9 13 6.2 0.0 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXX77671.1 - 1.2 9.5 4.4 86 3.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KXX77671.1 - 2 8.6 5.1 76 3.5 0.0 4.6 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KXX77671.1 - 2.9 8.9 6.4 63 4.8 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2722 PF10846.8 KXX77672.1 - 2.1e-07 30.3 0.0 2.1e-07 30.3 0.0 4.0 2 2 2 4 4 4 2 Protein of unknown function (DUF2722) V_ATPase_I PF01496.19 KXX77672.1 - 2.1 6.1 12.6 3.3 5.5 12.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF853 PF05872.12 KXX77672.1 - 6 5.3 7.6 10 4.6 7.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Ssl1 PF04056.14 KXX77673.1 - 2.4e-72 242.8 0.0 3.2e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KXX77673.1 - 4.1e-17 62.1 3.9 4.1e-17 62.1 3.9 3.2 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 KXX77673.1 - 2.2e-13 50.8 0.0 4.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 KXX77673.1 - 0.027 14.7 2.7 0.027 14.7 2.7 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain HATPase_c PF02518.26 KXX77674.1 - 8.2e-27 93.9 0.2 8.2e-27 93.9 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXX77674.1 - 7.3e-22 77.6 0.0 1.6e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 KXX77674.1 - 1.4e-20 73.3 0.4 1.6e-11 44.3 0.2 3.7 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 KXX77674.1 - 2.6e-20 72.2 0.1 6.3e-20 71.0 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KXX77674.1 - 1.4e-08 34.9 0.0 0.013 15.7 0.0 4.3 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 KXX77674.1 - 5.2e-07 29.6 0.0 0.033 14.2 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KXX77674.1 - 2e-06 28.0 0.5 7.2e-05 23.0 0.1 2.9 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 KXX77674.1 - 0.00046 20.1 0.0 0.28 11.3 0.0 2.6 2 0 0 2 2 2 2 PAS domain S10_plectin PF03501.15 KXX77675.1 - 6.7e-39 131.9 0.1 8.5e-39 131.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.12 KXX77676.1 - 5e-24 84.3 0.1 3.7e-23 81.5 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX77676.1 - 3.2e-15 56.2 0.0 6.3e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXX77676.1 - 2.7e-13 49.9 0.0 3.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXX77676.1 - 2.6e-08 35.0 0.0 4.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KXX77676.1 - 0.001 18.4 0.0 0.0024 17.2 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KXX77676.1 - 0.035 14.6 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXX77676.1 - 0.079 13.0 0.0 0.23 11.5 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXX77676.1 - 0.085 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 KXX77676.1 - 0.15 12.3 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain COX6B PF02297.17 KXX77677.1 - 3.7e-18 65.5 4.5 4.4e-18 65.3 4.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KXX77677.1 - 0.01 15.8 1.4 0.017 15.1 1.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KXX77677.1 - 0.041 13.8 1.1 0.047 13.7 0.7 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 KXX77677.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Sde2_N_Ubi PF13019.6 KXX77678.1 - 1.8e-62 210.0 0.0 2.4e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Serglycin PF04360.12 KXX77678.1 - 0.54 10.2 3.0 1.3 8.9 3.0 1.6 1 0 0 1 1 1 0 Serglycin RRM_1 PF00076.22 KXX77679.1 - 4.1e-17 61.7 0.0 7.9e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX77679.1 - 6.8e-06 26.1 0.0 9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KXX77679.1 - 0.0069 16.0 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXX77679.1 - 0.008 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Limkain b1 Nup35_RRM_2 PF14605.6 KXX77679.1 - 0.087 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXX77679.1 - 0.1 12.6 0.0 0.55 10.3 0.0 2.0 1 1 0 1 1 1 0 RNA binding motif B12D PF06522.11 KXX77680.1 - 3.4e-07 30.0 0.0 4.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DsbD_2 PF13386.6 KXX77680.1 - 0.08 12.9 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region GET2 PF08690.10 KXX77681.1 - 7e-57 193.4 0.0 8.4e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 DUF5336 PF17270.2 KXX77681.1 - 0.097 12.3 1.7 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5336) DEC-1_N PF04625.13 KXX77681.1 - 1.1 8.2 14.1 0.94 8.4 12.6 1.5 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region KAR9 PF08580.10 KXX77681.1 - 2.2 6.7 3.0 5.5 5.4 0.0 2.0 2 0 0 2 2 2 0 Yeast cortical protein KAR9 WD40 PF00400.32 KXX77682.1 - 1.2e-10 41.8 3.2 0.091 13.7 0.1 6.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.7 KXX77682.1 - 3.2e-09 36.9 0.0 2.1e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KXX77682.1 - 4.3e-05 23.3 21.0 4.3e-05 23.3 21.0 3.8 4 1 0 4 4 4 1 Steroid receptor RNA activator (SRA1) ANAPC4_WD40 PF12894.7 KXX77682.1 - 0.00011 22.4 0.1 0.22 11.9 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KXX77682.1 - 0.23 10.3 0.9 6.4 5.6 0.0 2.2 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain 2OG-FeII_Oxy_3 PF13640.6 KXX77683.1 - 1.5e-12 48.3 0.1 2.7e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 KXX77683.1 - 0.052 13.8 0.0 0.88 9.8 0.0 2.6 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_76 PF03663.14 KXX77685.1 - 4.2e-157 523.4 8.7 4.9e-157 523.1 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXX77685.1 - 0.0078 15.3 8.9 0.084 11.9 0.3 3.1 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 PCRF PF03462.18 KXX77686.1 - 7.2e-49 166.3 0.2 7.2e-49 166.3 0.2 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KXX77686.1 - 7.3e-34 116.2 3.8 7.3e-34 116.2 3.8 1.9 2 1 1 3 3 3 1 RF-1 domain DUF1912 PF08930.10 KXX77686.1 - 0.051 13.7 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Exonuc_VII_L PF02601.15 KXX77686.1 - 0.09 12.3 5.3 0.21 11.1 0.6 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Sigma70_ner PF04546.13 KXX77686.1 - 0.59 10.0 4.0 0.24 11.2 1.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4407 PF14362.6 KXX77686.1 - 3.6 6.8 8.5 5.2 6.3 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) tRNA-synt_1b PF00579.25 KXX77687.1 - 8.6e-16 58.1 0.7 3.7e-15 56.0 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) 2CSK_N PF08521.10 KXX77687.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal SAGA-Tad1 PF12767.7 KXX77688.1 - 2.3e-63 214.1 0.0 3.1e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit MRC1 PF09444.10 KXX77689.1 - 8e-45 152.9 21.7 8e-45 152.9 21.7 8.7 7 2 1 8 8 8 1 MRC1-like domain DIRP PF06584.13 KXX77689.1 - 7.3 6.8 7.9 0.3 11.3 1.0 2.3 2 0 0 2 2 2 0 DIRP UQ_con PF00179.26 KXX77690.1 - 1.1e-50 170.9 0.1 1.2e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX77690.1 - 4.1e-06 26.5 0.0 6.3e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXX77690.1 - 0.026 14.8 1.9 0.055 13.8 1.9 1.8 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 KXX77691.1 - 1.4e-92 311.1 0.0 2.5e-54 185.3 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXX77691.1 - 9e-37 125.7 0.0 1.4e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXX77691.1 - 1.4e-27 96.5 0.0 2.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXX77691.1 - 4.2e-07 29.6 0.0 7.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXX77691.1 - 0.00059 19.0 0.0 0.0021 17.2 0.0 1.8 1 1 0 1 1 1 1 NAD synthase GST_N_3 PF13417.6 KXX77692.1 - 6e-08 33.0 0.0 9.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX77692.1 - 1.2e-05 25.3 2.7 3.6e-05 23.7 2.7 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXX77692.1 - 2.4e-05 24.6 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 KXX77693.1 - 2.1e-31 109.2 59.0 3.2e-31 108.6 59.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX77693.1 - 9.7e-11 41.2 16.2 9.7e-11 41.2 16.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXX77693.1 - 2.1 6.5 14.3 0.042 12.1 3.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Amidohydro_2 PF04909.14 KXX77694.1 - 8.4e-08 32.3 0.1 1.2e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.20 KXX77694.1 - 1.1e-06 28.2 0.4 2.3e-06 27.2 0.4 1.6 1 1 0 1 1 1 1 Amidohydrolase family GCP_C_terminal PF04130.13 KXX77695.1 - 2.8e-99 332.5 0.2 4.8e-99 331.7 0.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXX77695.1 - 6.7e-83 278.8 0.1 1.9e-82 277.4 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Mso1_Sec1_bdg PF14475.6 KXX77696.1 - 6e-19 67.4 0.0 9.1e-19 66.8 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 KXX77697.1 - 4.1e-38 130.7 1.6 1.1e-37 129.3 1.6 1.7 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KXX77697.1 - 5.5e-29 100.7 17.8 5.5e-29 100.7 17.8 2.7 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KXX77697.1 - 2.1e-06 27.4 20.3 2.9e-06 26.9 20.3 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KXX77697.1 - 0.29 10.8 5.3 0.47 10.2 4.8 1.7 1 1 0 1 1 1 0 Conserved carboxylase domain DUF3040 PF11239.8 KXX77697.1 - 2.6 8.4 5.7 1.5 9.1 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) DnaJ PF00226.31 KXX77698.1 - 2.9e-19 68.9 0.4 4.3e-19 68.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 KXX77699.1 - 4.3e-73 246.1 9.1 4.8e-73 245.9 9.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin OMP_b-brl PF13505.6 KXX77699.1 - 0.059 13.5 9.7 0.022 14.9 6.2 1.9 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain PRELI PF04707.14 KXX77700.1 - 1.5e-42 145.0 0.3 2e-42 144.7 0.3 1.1 1 0 0 1 1 1 1 PRELI-like family Peptidase_M24 PF00557.24 KXX77701.1 - 3.6e-43 147.7 0.0 4.6e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 KXX77701.1 - 0.11 12.4 0.5 0.18 11.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) CCDC106 PF15794.5 KXX77701.1 - 0.59 9.8 4.5 1.1 8.9 4.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nefa_Nip30_N PF10187.9 KXX77701.1 - 1.5 9.2 7.3 3 8.2 7.3 1.4 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 PGA2 PF07543.12 KXX77701.1 - 4.8 7.2 10.2 3 7.8 7.9 1.8 1 1 0 1 1 1 0 Protein trafficking PGA2 AAA_18 PF13238.6 KXX77702.1 - 3.7e-05 24.3 0.0 0.00038 21.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KXX77702.1 - 0.00026 20.8 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KXX77702.1 - 0.00029 20.1 0.0 0.00041 19.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 KXX77702.1 - 0.0022 17.3 0.0 0.008 15.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KXX77702.1 - 0.0024 18.0 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXX77702.1 - 0.0032 16.6 0.0 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 KXX77702.1 - 0.013 15.9 0.1 0.05 14.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXX77702.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXX77702.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 KXX77702.1 - 0.098 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXX77702.1 - 0.12 12.8 0.1 0.51 10.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXX77702.1 - 0.14 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KXX77702.1 - 0.21 11.3 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase Alpha-E PF04168.12 KXX77703.1 - 0.033 14.0 1.2 0.098 12.4 1.2 1.9 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. CAP_N PF01213.19 KXX77704.1 - 0.13 11.7 1.2 0.16 11.5 1.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC1 PF03109.16 KXX77706.1 - 2.1e-31 108.6 0.0 3.6e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Aldo_ket_red PF00248.21 KXX77707.1 - 1.5e-72 244.3 0.0 1.6e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Transthyretin PF00576.21 KXX77708.1 - 9.3e-36 122.9 0.1 2.5e-35 121.5 0.1 1.7 1 1 0 1 1 1 1 HIUase/Transthyretin family SecE PF00584.20 KXX77710.1 - 2.2e-13 49.9 0.0 2.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Dioxygenase_N PF04444.14 KXX77710.1 - 0.095 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Catechol dioxygenase N terminus MKT1_C PF12246.8 KXX77711.1 - 4.7e-74 248.7 0.0 6.4e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KXX77711.1 - 5.1e-33 113.3 0.1 1.4e-32 111.9 0.1 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KXX77711.1 - 0.075 13.5 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 XPG N-terminal domain Peptidase_S10 PF00450.22 KXX77712.1 - 7.1e-81 272.7 0.0 9.5e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PRELI PF04707.14 KXX77713.1 - 4.9e-21 75.2 0.0 2.2e-18 66.6 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family DWNN PF08783.11 KXX77714.1 - 1e-28 99.4 0.0 2e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KXX77714.1 - 7.6e-09 35.2 5.6 1.4e-08 34.3 5.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KXX77714.1 - 0.00065 19.7 0.9 0.0013 18.7 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KXX77714.1 - 0.004 17.0 9.4 0.004 17.0 9.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 KXX77714.1 - 0.028 14.4 0.5 0.068 13.2 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-RING_4 PF14570.6 KXX77714.1 - 0.099 12.5 6.5 0.26 11.1 6.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KXX77714.1 - 0.12 12.3 5.9 0.26 11.1 5.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KXX77714.1 - 0.25 11.7 6.8 0.58 10.5 6.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 KXX77714.1 - 0.79 9.9 10.2 2.4 8.4 10.2 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXX77714.1 - 5.5 7.0 11.3 0.47 10.5 5.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KXX77714.1 - 6.4 6.7 10.1 13 5.8 10.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ArsA_ATPase PF02374.15 KXX77715.1 - 1.1e-112 376.1 0.0 1.3e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KXX77715.1 - 4.5e-13 49.5 0.2 8.2e-12 45.4 0.0 2.7 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 KXX77715.1 - 2.3e-12 47.1 0.0 3.5e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KXX77715.1 - 1.4e-06 27.9 0.2 0.00021 20.8 0.1 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KXX77715.1 - 6.7e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KXX77715.1 - 3.8e-05 23.4 0.1 0.0016 18.1 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KXX77715.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 KXX77715.1 - 0.027 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KXX77715.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXX77715.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KXX77715.1 - 0.13 12.8 0.1 0.36 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain MnmE_helical PF12631.7 KXX77717.1 - 2.1e-33 116.2 0.2 3.2e-33 115.7 0.2 1.3 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KXX77717.1 - 2.1e-22 79.6 0.0 4.8e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KXX77717.1 - 1e-19 70.7 0.0 2.4e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX77717.1 - 5.1e-07 29.4 0.1 2.6e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXX77717.1 - 8.3e-05 22.7 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 KXX77717.1 - 0.0025 17.8 0.1 0.051 13.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Glyco_hydro_3_C PF01915.22 KXX77717.1 - 0.0042 17.1 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.6 KXX77717.1 - 0.0049 16.6 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KXX77717.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KXX77717.1 - 0.063 13.7 0.0 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KXX77717.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SGS PF05002.15 KXX77719.1 - 1.6e-30 105.1 3.5 3.7e-30 103.9 3.5 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KXX77719.1 - 1.1e-11 45.5 0.0 2.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 KXX77719.1 - 1.9e-07 30.6 0.5 0.33 10.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX77719.1 - 7.4e-07 28.8 4.6 0.26 11.5 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX77719.1 - 3.7e-06 26.7 2.1 0.42 11.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX77719.1 - 0.0001 22.8 7.6 0.00097 19.7 4.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX77719.1 - 0.0013 19.0 6.9 0.11 12.8 5.9 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 KXX77719.1 - 0.0016 18.6 0.5 0.0033 17.5 0.5 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 KXX77719.1 - 0.0037 17.8 3.7 0.018 15.5 0.9 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX77719.1 - 0.24 11.5 3.2 89 3.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX77719.1 - 0.26 11.6 2.9 0.35 11.1 1.0 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXX77719.1 - 3.6 7.6 7.4 23 5.0 1.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_21 PF13506.6 KXX77720.1 - 1.1e-10 41.2 0.0 0.00024 20.6 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KXX77720.1 - 4.8e-06 26.6 0.0 1.5e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 AA_permease PF00324.21 KXX77721.1 - 8.4e-139 463.2 37.3 1.1e-138 462.9 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX77721.1 - 1.5e-39 136.0 35.8 1.9e-39 135.7 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease GW PF13457.6 KXX77722.1 - 6.3e-06 26.7 8.8 2.5 8.8 1.2 4.7 2 2 3 5 5 5 5 GW (Gly-Tryp) dipeptide domain Ribosomal_L17 PF01196.19 KXX77722.1 - 0.00054 20.8 2.2 4.2 8.3 0.0 4.6 2 2 5 7 7 7 2 Ribosomal protein L17 nsp8 PF08717.10 KXX77722.1 - 0.0032 17.4 6.7 20 5.0 0.1 4.6 2 2 2 5 5 5 1 nsp8 replicase zf-U1 PF06220.12 KXX77722.1 - 1.1 9.1 3.7 28 4.6 0.1 3.1 2 1 1 3 3 3 0 U1 zinc finger NTR PF01759.21 KXX77722.1 - 1.9 8.4 6.2 40 4.1 0.2 3.6 2 2 2 4 4 4 0 UNC-6/NTR/C345C module DUF3328 PF11807.8 KXX77723.1 - 2.4e-45 155.0 0.5 2.9e-45 154.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.20 KXX77724.1 - 2.4e-35 122.8 1.2 5.7e-35 121.6 1.2 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase gag_pre-integrs PF13976.6 KXX77724.1 - 0.025 14.5 0.3 0.058 13.3 0.3 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain ABC_tran PF00005.27 KXX77725.1 - 4.6e-39 134.1 0.0 3.9e-19 69.5 0.0 3.5 3 1 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 KXX77725.1 - 8.2e-25 88.0 26.0 2.3e-21 76.7 18.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KXX77725.1 - 8.5e-11 42.2 1.0 0.007 16.2 0.1 3.9 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX77725.1 - 1.4e-10 41.0 0.3 0.0058 16.1 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXX77725.1 - 4.9e-07 29.4 0.4 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KXX77725.1 - 0.00011 22.1 0.0 0.16 11.7 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXX77725.1 - 0.00016 21.7 0.1 0.43 10.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXX77725.1 - 0.0003 21.1 0.3 0.75 10.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KXX77725.1 - 0.00035 20.6 0.1 0.99 9.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KXX77725.1 - 0.00044 20.8 0.0 0.35 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXX77725.1 - 0.00054 20.4 0.2 1.8 8.9 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KXX77725.1 - 0.0021 18.2 0.3 0.6 10.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KXX77725.1 - 0.0095 16.5 0.2 3 8.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KXX77725.1 - 0.027 13.5 0.1 0.094 11.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KXX77725.1 - 0.061 13.4 0.1 8.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_25 PF13481.6 KXX77725.1 - 0.23 11.0 1.3 31 4.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain Glyco_hydro_31 PF01055.26 KXX77726.1 - 1.2e-150 502.6 3.4 1.8e-150 502.0 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXX77726.1 - 1.8e-23 82.9 0.1 3.2e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXX77726.1 - 1.2e-11 44.7 2.0 1.9e-11 44.1 0.4 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXX77726.1 - 0.056 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) DUF3328 PF11807.8 KXX77727.1 - 0.06 13.1 6.7 1.3 8.8 6.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) SMRP1 PF15181.6 KXX77727.1 - 0.06 12.9 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 tRNA_int_endo PF01974.17 KXX77728.1 - 7.2e-19 67.6 0.0 2e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KXX77728.1 - 4.8e-05 23.0 0.0 0.063 13.0 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain FAD_binding_3 PF01494.19 KXX77729.1 - 3.2e-14 52.9 4.9 5.9e-13 48.8 1.2 2.9 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXX77729.1 - 0.00012 21.8 0.2 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX77729.1 - 0.0029 16.9 0.1 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX77729.1 - 0.0051 16.0 0.8 0.0073 15.4 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KXX77729.1 - 0.0081 16.7 0.2 0.019 15.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX77729.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXX77729.1 - 0.064 11.9 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KXX77729.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXX77729.1 - 0.083 12.2 0.0 5.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pkinase PF00069.25 KXX77730.1 - 9.7e-28 97.3 0.0 1.1e-26 93.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77730.1 - 8.1e-10 38.4 0.0 2.6e-08 33.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX77730.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXX77730.1 - 0.13 12.2 0.0 3.8 7.4 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Sec39 PF08314.11 KXX77732.1 - 9.8e-285 946.8 0.0 1.2e-284 946.5 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Methyltransf_PK PF05891.12 KXX77733.1 - 1e-78 263.9 0.0 1.2e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KXX77733.1 - 7.6e-06 26.6 0.0 1.6e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX77733.1 - 7.8e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77733.1 - 3.3e-05 24.5 0.0 5.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXX77733.1 - 6.2e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KXX77733.1 - 0.0012 19.6 0.0 0.0022 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Succ_CoA_lig PF13607.6 KXX77733.1 - 0.03 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain GCD14 PF08704.10 KXX77734.1 - 4.5e-64 216.5 0.0 2.2e-46 158.5 0.0 2.8 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit DIOX_N PF14226.6 KXX77735.1 - 2.8e-19 70.0 0.0 4.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXX77735.1 - 5.5e-13 49.3 0.0 1.1e-11 45.1 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MS_channel PF00924.18 KXX77736.1 - 2e-20 73.2 2.6 3.7e-20 72.3 2.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KXX77736.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KXX77736.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KXX77736.1 - 0.19 11.3 0.3 0.48 10.1 0.3 1.7 1 0 0 1 1 1 0 EF hand Glyco_hydro_31 PF01055.26 KXX77738.1 - 9.2e-142 473.3 4.4 1.3e-141 472.8 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXX77738.1 - 2.5e-25 88.6 0.5 1e-23 83.4 0.2 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXX77738.1 - 2.9e-07 30.7 0.9 1.9e-06 28.0 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Peptidase_A4 PF01828.17 KXX77739.1 - 2.3e-34 118.7 2.3 4.4e-33 114.5 2.3 2.0 1 1 0 1 1 1 1 Peptidase A4 family T7SS_ESX_EspC PF10824.8 KXX77740.1 - 0.015 15.8 1.2 0.015 15.8 1.2 1.9 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm NDK PF00334.19 KXX77741.1 - 1.3e-53 180.6 0.0 1.5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase TP6A_N PF04406.14 KXX77742.1 - 4.3e-21 74.7 0.0 1.1e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase NPR2 PF06218.11 KXX77742.1 - 0.09 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrogen permease regulator 2 SQHop_cyclase_C PF13243.6 KXX77743.1 - 3.6e-45 154.5 1.0 1.5e-42 145.9 0.7 2.7 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXX77743.1 - 1.3e-36 126.2 7.4 3.6e-33 114.9 2.2 3.6 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KXX77743.1 - 1.7e-26 91.6 9.6 5e-08 32.5 0.3 5.4 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KXX77743.1 - 7.6e-05 21.9 0.1 0.02 13.9 0.0 3.3 3 1 1 4 4 4 1 A-macroglobulin TED domain Pec_lyase PF09492.10 KXX77743.1 - 0.0026 17.1 0.1 0.71 9.1 0.0 3.5 2 1 1 3 3 3 1 Pectic acid lyase Cytomega_TRL10 PF06084.11 KXX77743.1 - 0.24 11.4 0.4 0.45 10.5 0.4 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Ank_4 PF13637.6 KXX77744.1 - 9.7e-20 70.7 0.8 4.7e-09 36.6 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX77744.1 - 2.4e-15 56.9 0.1 1.6e-07 31.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX77744.1 - 4.5e-15 55.5 1.0 5.3e-09 36.2 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX77744.1 - 5.3e-11 42.5 1.1 0.00012 22.4 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXX77744.1 - 1.3e-10 40.5 0.1 0.00058 20.1 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ketoacyl-synt_2 PF13723.6 KXX77744.1 - 0.061 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain p450 PF00067.22 KXX77745.1 - 4.3e-30 104.9 0.1 6e-29 101.1 0.1 2.3 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 KXX77746.1 - 2.9e-13 50.9 2.8 4.3e-13 50.4 2.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX77746.1 - 7.7e-06 25.3 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX77746.1 - 0.0024 17.5 0.2 0.0064 16.2 0.1 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2789 PF10982.8 KXX77746.1 - 0.086 13.0 0.1 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) Conotoxin PF02950.17 KXX77747.1 - 0.063 14.3 0.0 0.1 13.6 0.0 1.2 1 0 0 1 1 1 0 Conotoxin APH PF01636.23 KXX77749.1 - 8.2e-19 68.5 0.8 1.5e-17 64.4 0.8 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXX77749.1 - 0.025 13.4 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Cu-oxidase_3 PF07732.15 KXX77750.1 - 6.9e-42 142.2 2.3 8.4e-42 142.0 0.6 2.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXX77750.1 - 5.5e-41 139.5 6.1 6.6e-37 126.3 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXX77750.1 - 1.8e-34 119.2 0.0 1.2e-33 116.5 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase DUF3987 PF13148.6 KXX77750.1 - 0.29 10.1 0.0 0.42 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GatB_N PF02934.15 KXX77751.1 - 2.2e-97 325.7 0.0 2.9e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KXX77751.1 - 2.2e-07 30.9 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 GatB domain Patatin PF01734.22 KXX77753.1 - 6.6e-05 23.2 0.1 8.5e-05 22.8 0.1 1.2 1 1 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.6 KXX77754.1 - 5.5e-58 193.2 18.2 5.7e-22 77.8 1.4 5.9 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXX77754.1 - 2.7e-53 176.5 14.9 2.6e-14 52.5 0.4 6.9 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXX77754.1 - 8.8e-21 72.4 7.1 0.00027 20.7 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KXX77754.1 - 4.1e-18 65.5 0.0 5.6e-17 61.8 0.0 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_1 PF00515.28 KXX77754.1 - 2.5e-16 58.7 7.2 0.00048 19.8 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX77754.1 - 1.6e-14 52.7 6.2 0.0039 17.2 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX77754.1 - 9.7e-11 41.0 7.7 0.0081 16.3 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX77754.1 - 1.5e-09 37.7 9.0 3.6e-09 36.4 9.0 1.6 1 1 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 KXX77754.1 - 2.5e-09 37.2 1.1 1 10.4 0.0 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX77754.1 - 3.7e-09 37.1 1.5 0.019 15.6 0.3 5.3 4 1 2 6 6 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXX77754.1 - 3.5e-08 33.8 2.5 0.026 15.0 0.7 4.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 KXX77754.1 - 1.6e-07 31.1 1.6 0.74 9.9 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXX77754.1 - 2.2e-07 30.9 0.0 0.7 10.7 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 KXX77754.1 - 2.9e-07 30.0 0.0 4.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 KXX77754.1 - 2e-05 24.7 4.7 0.021 15.0 0.3 4.6 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXX77754.1 - 2.5e-05 24.3 3.0 2 8.9 0.1 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.18 KXX77754.1 - 7.1e-05 22.8 1.6 1.4 9.0 0.0 4.3 3 1 2 5 5 3 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KXX77754.1 - 9.5e-05 22.0 11.9 2 8.2 0.1 6.0 6 0 0 6 6 6 2 TPR repeat NACHT PF05729.12 KXX77754.1 - 0.00064 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.6 KXX77754.1 - 0.0021 18.6 6.4 1.4 9.8 0.1 5.9 6 0 0 6 6 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KXX77754.1 - 0.0032 17.9 0.7 0.027 14.9 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain NRBF2_MIT PF17169.4 KXX77754.1 - 0.0035 17.5 0.1 27 5.1 0.0 4.7 4 1 1 5 5 5 0 MIT domain of nuclear receptor-binding factor 2 Wzy_C_2 PF11846.8 KXX77754.1 - 0.0076 16.2 0.7 0.82 9.6 0.1 2.9 1 1 1 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_5 PF12688.7 KXX77754.1 - 0.011 16.0 0.7 0.049 13.9 0.7 2.2 1 1 0 1 1 1 0 Tetratrico peptide repeat TPR_15 PF13429.6 KXX77754.1 - 0.013 14.8 3.3 0.031 13.5 0.1 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 KXX77754.1 - 0.037 14.3 0.0 0.2 11.9 0.0 2.3 2 0 0 2 2 1 0 AAA domain DUF1897 PF09005.10 KXX77754.1 - 1.5 8.3 8.9 1.4 8.5 0.3 4.4 5 0 0 5 5 4 0 Domain of unknown function (DUF1897) CRAL_TRIO PF00650.20 KXX77755.1 - 1e-13 51.3 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXX77755.1 - 4e-06 26.9 0.0 0.00024 21.2 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Asp PF00026.23 KXX77756.1 - 3.4e-21 76.0 0.0 4.2e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Fea1 PF07692.11 KXX77758.1 - 0.026 13.6 0.3 0.035 13.2 0.3 1.2 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein YkpC PF17447.2 KXX77758.1 - 1.2 10.1 4.4 4.1 8.4 0.8 2.7 2 0 0 2 2 2 0 Uncharacterized YkpC-like CesT PF05932.13 KXX77759.1 - 0.011 15.9 0.4 0.032 14.4 0.1 1.9 1 1 1 2 2 2 0 Tir chaperone protein (CesT) family adh_short_C2 PF13561.6 KXX77760.1 - 4.6e-52 176.9 0.0 6e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX77760.1 - 1.3e-46 158.6 0.2 1.6e-46 158.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX77760.1 - 1.6e-08 34.7 0.1 2e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX77760.1 - 0.00018 21.0 0.0 0.00023 20.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXX77760.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KXX77760.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2974 PF11187.8 KXX77760.1 - 0.078 12.5 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) GMC_oxred_N PF00732.19 KXX77761.1 - 4.9e-31 108.2 0.0 2.4e-29 102.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX77761.1 - 5e-30 104.9 0.1 1.5e-29 103.4 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXX77761.1 - 0.00058 19.2 0.0 0.00098 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX77761.1 - 0.0039 16.3 0.0 0.03 13.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXX77761.1 - 0.024 14.8 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX77761.1 - 0.07 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXX77761.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase peroxidase PF00141.23 KXX77763.1 - 7.8e-85 284.2 0.0 1.1e-45 156.2 0.0 2.4 2 0 0 2 2 2 2 Peroxidase EthD PF07110.11 KXX77763.1 - 0.19 12.9 1.1 0.34 12.1 0.3 1.8 2 0 0 2 2 2 0 EthD domain Acetyltransf_10 PF13673.7 KXX77764.1 - 1.6e-05 24.8 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX77764.1 - 8.4e-05 22.8 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX77764.1 - 0.0004 20.7 0.0 0.00067 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase_fungal PF17667.1 KXX77765.1 - 2.8e-134 447.9 0.0 3.4e-134 447.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXX77765.1 - 5.9e-05 23.1 2.9 0.00061 19.8 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KXX77765.1 - 0.003 17.0 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77765.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 KXX77765.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family TPR_12 PF13424.6 KXX77766.1 - 4.2e-25 87.8 7.3 3.7e-12 46.4 0.4 3.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXX77766.1 - 4e-20 71.0 4.8 3.2e-07 30.0 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 KXX77766.1 - 3.8e-14 52.5 0.0 6.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 KXX77766.1 - 1e-09 38.8 2.2 0.0004 20.8 0.3 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXX77766.1 - 6.9e-09 35.8 1.3 0.027 15.1 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXX77766.1 - 2.9e-08 33.9 5.7 0.012 16.0 0.2 4.6 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX77766.1 - 2.1e-07 30.5 1.0 0.64 10.3 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXX77766.1 - 2.4e-07 31.0 2.9 0.14 13.0 0.2 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX77766.1 - 7.2e-06 25.7 1.7 0.054 13.5 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 KXX77766.1 - 8.7e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXX77766.1 - 1.6e-05 25.2 0.0 8.3e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_16 PF13432.6 KXX77766.1 - 2.4e-05 24.9 4.1 0.0043 17.7 2.5 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX77766.1 - 0.00011 22.4 0.1 0.069 13.4 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXX77766.1 - 0.00018 21.5 0.3 17 5.9 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXX77766.1 - 0.0012 19.3 4.6 0.33 11.7 0.9 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 KXX77766.1 - 0.0053 17.2 3.1 0.012 16.0 0.2 2.9 2 2 0 2 2 2 1 AAA ATPase domain TPR_1 PF00515.28 KXX77766.1 - 0.012 15.4 0.0 8.3 6.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_25 PF13481.6 KXX77766.1 - 0.017 14.7 2.1 0.028 14.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 KXX77766.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Vps39_1 PF10366.9 KXX77766.1 - 0.097 13.0 0.4 3 8.1 0.1 2.8 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 Sugar_tr PF00083.24 KXX77767.1 - 4e-76 256.7 22.9 5.1e-76 256.4 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX77767.1 - 1.9e-23 83.0 30.7 1.9e-23 83.0 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SesA PF17107.5 KXX77768.1 - 1.1e-07 32.1 2.4 1.3e-07 31.9 0.3 2.3 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXX77768.1 - 3e-05 23.5 0.7 7.8e-05 22.1 0.7 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KXX77768.1 - 0.00063 19.7 0.2 0.0014 18.6 0.2 1.6 1 0 0 1 1 1 1 NACHT domain YPEB PF14620.6 KXX77768.1 - 0.06 12.7 1.2 0.1 11.9 0.9 1.4 1 1 0 1 1 1 0 YpeB sporulation AAA_22 PF13401.6 KXX77768.1 - 0.061 13.6 0.0 0.64 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain cwf21 PF08312.12 KXX77768.1 - 0.071 13.3 0.7 0.67 10.1 0.0 2.7 2 0 0 2 2 2 0 cwf21 domain Baculo_PEP_C PF04513.12 KXX77768.1 - 0.38 10.8 1.8 29 4.7 0.1 3.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 KXX77770.1 - 4.5e-29 101.5 25.4 3.6e-28 98.5 24.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KXX77770.1 - 0.034 13.9 3.4 0.17 11.7 0.2 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain MASE2 PF05230.11 KXX77770.1 - 0.048 13.7 4.3 0.5 10.5 0.7 2.8 2 0 0 2 2 2 0 MASE2 domain PLAC8 PF04749.17 KXX77772.1 - 1.2e-20 74.3 11.2 1.5e-20 74.0 11.2 1.1 1 0 0 1 1 1 1 PLAC8 family FAA_hydrolase PF01557.18 KXX77773.1 - 3e-57 193.8 0.0 5.8e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXX77773.1 - 2.1e-32 111.5 0.0 4.2e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal RNase_H PF00075.24 KXX77774.1 - 1.7e-11 44.5 0.0 5.7e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 RNase H WD40 PF00400.32 KXX77775.1 - 9.7e-22 76.9 10.4 5.2e-11 42.9 0.5 3.3 4 0 0 4 4 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX77775.1 - 1.5e-08 34.8 0.0 0.00082 19.6 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX77775.1 - 8.7e-07 28.0 0.3 0.077 11.6 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF1652 PF07865.11 KXX77775.1 - 0.00014 21.6 0.0 1.9 8.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1652) IKI3 PF04762.12 KXX77775.1 - 0.00023 19.3 0.7 0.22 9.5 0.1 2.0 1 1 1 2 2 2 2 IKI3 family PALB2_WD40 PF16756.5 KXX77775.1 - 0.0038 16.2 2.7 0.32 9.9 0.4 2.4 1 1 2 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 KXX77775.1 - 0.0058 16.0 1.5 0.54 9.5 0.1 2.1 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Lipoprotein_15 PF03640.15 KXX77775.1 - 0.015 14.8 1.2 0.25 10.9 0.1 2.9 3 0 0 3 3 3 0 Secreted repeat of unknown function ESPR PF13018.6 KXX77775.1 - 0.019 14.8 0.0 15 5.5 0.0 3.1 3 0 0 3 3 3 0 Extended Signal Peptide of Type V secretion system eIF2A PF08662.11 KXX77775.1 - 0.025 14.5 0.0 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WXG100 PF06013.12 KXX77775.1 - 0.046 14.0 0.0 2.1 8.6 0.0 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Ge1_WD40 PF16529.5 KXX77775.1 - 0.063 12.2 1.0 1.5 7.7 1.0 2.2 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Foamy_BEL PF03274.14 KXX77775.1 - 0.13 11.6 0.1 2.3 7.5 0.0 2.0 1 1 1 2 2 2 0 Foamy virus BEL 1/2 protein TcfC PF16967.5 KXX77775.1 - 0.18 11.3 0.0 22 4.7 0.0 2.2 2 0 0 2 2 2 0 E-set like domain Cytochrom_B561 PF03188.16 KXX77776.1 - 0.018 15.2 8.4 0.099 12.8 8.7 2.0 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 Adeno_E3 PF06040.11 KXX77776.1 - 0.41 10.8 2.4 13 6.0 0.2 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein DUF4079 PF13301.6 KXX77776.1 - 0.61 10.2 13.4 0.68 10.1 9.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 KXX77776.1 - 1.6 8.3 12.8 7.2 6.2 11.7 2.4 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 CPDase PF07823.11 KXX77779.1 - 3.2e-21 76.0 0.0 1.7e-15 57.3 0.0 2.1 1 1 1 2 2 2 2 Cyclic phosphodiesterase-like protein SH3_3 PF08239.11 KXX77780.1 - 0.0029 17.8 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KXX77780.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Tfb2 PF03849.14 KXX77783.1 - 5e-135 450.0 0.0 6.1e-135 449.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KXX77783.1 - 8.4e-23 80.6 0.2 1.5e-22 79.7 0.2 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KXX77783.1 - 1.6e-05 25.0 0.2 3.2e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain F-box-like PF12937.7 KXX77785.1 - 3.5e-06 26.8 0.1 1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX77785.1 - 0.00052 19.8 1.5 0.002 17.9 1.5 2.1 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 KXX77785.1 - 0.044 13.8 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain DOG1 PF14144.6 KXX77785.1 - 0.062 13.5 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Seed dormancy control Pkinase PF00069.25 KXX77786.1 - 5.5e-23 81.7 0.0 1.9e-22 79.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77786.1 - 6.5e-09 35.4 0.0 2.5e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXX77786.1 - 0.018 15.0 0.3 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXX77786.1 - 0.03 13.7 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 4HBT PF03061.22 KXX77788.1 - 1e-12 48.2 0.1 1.6e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KXX77788.1 - 0.021 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) VPS13_C PF16909.5 KXX77789.1 - 0.059 13.1 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal MT0933_antitox PF14013.6 KXX77789.1 - 7.7 6.9 9.7 31 5.0 9.7 2.0 1 1 0 1 1 1 0 MT0933-like antitoxin protein HMGL-like PF00682.19 KXX77790.1 - 1.3e-78 264.2 0.2 1.8e-78 263.7 0.2 1.2 1 0 0 1 1 1 1 HMGL-like DUF4213 PF13938.6 KXX77790.1 - 0.032 14.5 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 Putative heavy-metal chelation TANGO2 PF05742.12 KXX77791.1 - 1.5e-63 215.3 0.0 8.7e-62 209.4 0.0 2.0 1 1 0 1 1 1 1 Transport and Golgi organisation 2 adh_short PF00106.25 KXX77792.1 - 2.2e-12 46.9 0.0 2.8e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX77792.1 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F-box_4 PF15966.5 KXX77794.1 - 1.2e-09 38.1 0.1 0.0008 19.3 0.0 2.5 2 0 0 2 2 2 2 F-box F-box-like PF12937.7 KXX77794.1 - 6.8e-09 35.5 0.3 0.0021 17.9 0.0 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KXX77794.1 - 2e-07 30.7 6.5 0.0016 18.3 0.1 3.0 3 0 0 3 3 3 2 F-box domain Fungal_trans PF04082.18 KXX77795.1 - 1.8e-11 43.6 0.1 4.7e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX77795.1 - 1.4e-06 28.4 7.4 2.5e-06 27.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LPP PF04728.13 KXX77795.1 - 0.0039 17.6 0.8 0.13 12.7 0.2 2.7 2 0 0 2 2 2 1 Lipoprotein leucine-zipper Peptidase_M43 PF05572.13 KXX77796.1 - 4.9e-17 62.2 0.2 7.8e-17 61.6 0.2 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXX77796.1 - 4.9e-07 30.1 0.1 7.1e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXX77796.1 - 8.5e-07 29.5 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXX77796.1 - 0.0001 22.0 0.3 0.00019 21.1 0.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXX77796.1 - 0.0028 17.6 0.2 0.0043 17.0 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXX77796.1 - 0.03 14.2 0.1 0.088 12.6 0.1 1.4 1 1 0 1 1 1 0 Matrixin DUF4953 PF16313.5 KXX77796.1 - 0.045 13.0 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 KXX77796.1 - 0.059 13.0 0.2 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 KXX77796.1 - 0.12 12.4 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.8 KXX77796.1 - 0.21 10.1 0.5 0.29 9.7 0.5 1.1 1 0 0 1 1 1 0 Putative peptidase family 2OG-FeII_Oxy_2 PF13532.6 KXX77797.1 - 3.1e-17 63.4 0.0 1.7e-16 61.0 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cu-oxidase_3 PF07732.15 KXX77798.1 - 3.4e-41 140.0 2.9 3.6e-41 139.9 0.9 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXX77798.1 - 1.2e-32 112.5 9.2 6.4e-25 87.5 1.8 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXX77798.1 - 3.4e-13 50.0 0.0 2.7e-10 40.6 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Peptidase_M57 PF12388.8 KXX77800.1 - 0.0023 17.6 0.4 1.6 8.2 0.1 2.1 1 1 1 2 2 2 2 Dual-action HEIGH metallo-peptidase 4HBT PF03061.22 KXX77801.1 - 3e-07 30.7 0.5 1.1e-06 28.9 0.3 2.0 2 1 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 KXX77802.1 - 0.0044 17.5 0.0 0.0075 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily SKG6 PF08693.10 KXX77803.1 - 0.0023 17.3 0.4 0.0023 17.3 0.4 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Fungal_lectin PF07938.12 KXX77803.1 - 0.013 14.9 0.1 0.21 11.0 0.1 2.5 2 1 1 3 3 3 0 Fungal fucose-specific lectin ATPgrasp_N PF18130.1 KXX77804.1 - 8.7e-19 67.9 0.1 2.2e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KXX77804.1 - 3.9e-10 39.6 0.0 1.3e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXX77804.1 - 2e-06 27.5 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Collagen PF01391.18 KXX77804.1 - 0.00037 20.2 3.3 0.00062 19.5 3.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ATP-grasp_3 PF02655.14 KXX77804.1 - 0.0035 17.4 1.7 0.0066 16.5 0.0 2.3 3 0 0 3 3 3 1 ATP-grasp domain NAS PF03059.16 KXX77805.1 - 3e-69 233.4 0.0 4e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Nicotianamine synthase protein Rhodanese PF00581.20 KXX77807.1 - 3.9e-07 30.6 0.0 5.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Topo_Zn_Ribbon PF08272.11 KXX77807.1 - 0.14 11.8 0.1 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Dioxygenase_C PF00775.21 KXX77809.1 - 5.9e-06 25.8 0.1 1.1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Epimerase PF01370.21 KXX77811.1 - 4.9e-07 29.5 0.0 8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX77811.1 - 0.00018 21.5 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXX77811.1 - 0.0003 20.3 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXX77811.1 - 0.0037 16.3 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXX77811.1 - 0.0074 15.9 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Hexapep PF00132.24 KXX77812.1 - 2.6e-07 30.1 5.6 0.00032 20.3 0.7 3.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXX77812.1 - 0.0014 18.3 1.9 0.02 14.6 0.2 2.6 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXX77812.1 - 0.068 12.1 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase CorA PF01544.18 KXX77813.1 - 1.4e-06 27.8 0.1 2.5e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SIS PF01380.22 KXX77815.1 - 3.8e-14 52.7 0.4 3.9e-13 49.4 0.0 2.2 2 1 0 2 2 2 1 SIS domain SIS_2 PF13580.6 KXX77815.1 - 0.0047 16.9 0.1 0.13 12.3 0.2 2.4 1 1 1 2 2 2 1 SIS domain LMWPc PF01451.21 KXX77816.1 - 2e-40 138.4 0.0 2.3e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Proteasome PF00227.26 KXX77817.1 - 1.9e-47 161.2 0.0 2.6e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXX77817.1 - 1.4e-13 50.2 0.1 1.4e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.9 KXX77818.1 - 3.5e-25 87.6 1.2 6.2e-25 86.8 0.4 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Pkinase PF00069.25 KXX77819.1 - 2e-68 230.6 0.0 2.4e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77819.1 - 1.7e-31 109.5 0.0 2.4e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXX77819.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXX77819.1 - 0.039 13.3 0.1 0.075 12.4 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX77819.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3455 PF11937.8 KXX77820.1 - 1.5e-30 106.7 0.0 1.9e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) zf-C2H2_4 PF13894.6 KXX77821.1 - 0.39 11.7 0.2 0.39 11.7 0.2 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger Elf1 PF05129.13 KXX77821.1 - 1.3 9.1 6.5 0.54 10.4 0.7 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DOCK_N PF16172.5 KXX77822.1 - 3.2e-125 418.0 0.0 5e-125 417.3 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KXX77822.1 - 1.2e-36 126.3 0.0 2.1e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KXX77822.1 - 3.3e-30 105.2 1.7 2.5e-29 102.3 1.7 2.0 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 KXX77822.1 - 9.4e-06 25.1 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX77822.1 - 0.0014 18.5 0.0 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain CN_hydrolase PF00795.22 KXX77825.1 - 1.2e-33 116.6 0.1 6e-25 88.1 0.0 2.6 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase Cupin_5 PF06172.11 KXX77826.1 - 1.1e-45 155.3 0.0 1.5e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) DUF1999 PF09390.10 KXX77826.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1999) Glyco_hydro_61 PF03443.14 KXX77827.1 - 1.1e-25 90.8 0.0 1.1e-21 77.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 SDA1 PF05285.12 KXX77828.1 - 1.5e-86 291.0 46.6 1.5e-86 291.0 46.6 2.7 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KXX77828.1 - 4.6e-21 74.9 0.1 1.3e-20 73.5 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain EABR PF12180.8 KXX77828.1 - 0.012 15.2 0.7 0.028 14.0 0.7 1.6 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Dict-STAT-coil PF09267.10 KXX77828.1 - 0.083 13.3 0.3 0.41 11.0 0.1 2.3 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Ank_2 PF12796.7 KXX77829.1 - 4.6e-29 100.8 1.8 1.5e-13 51.1 0.1 5.4 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXX77829.1 - 2.3e-26 91.0 1.4 0.0024 18.2 0.1 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KXX77829.1 - 2.3e-24 85.4 0.0 1.7e-06 28.5 0.0 7.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX77829.1 - 2.5e-20 72.3 0.1 5.8e-08 32.8 0.0 5.8 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77829.1 - 3.4e-20 70.0 0.2 0.04 14.5 0.0 8.0 7 2 0 7 7 7 5 Ankyrin repeat Dioxygenase_C PF00775.21 KXX77831.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.20 KXX77832.1 - 2.5e-31 109.7 0.4 3.4e-31 109.3 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Methyltransf_23 PF13489.6 KXX77833.1 - 7.6e-11 42.1 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77833.1 - 0.0066 17.2 0.0 0.02 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77833.1 - 0.0089 16.7 0.0 0.023 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain bZIP_1 PF00170.21 KXX77836.1 - 1.1e-08 35.1 10.9 1.1e-08 35.1 10.9 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXX77836.1 - 0.011 15.9 12.6 0.011 15.9 12.6 2.7 2 0 0 2 2 2 0 Basic region leucine zipper Spt20 PF12090.8 KXX77836.1 - 0.061 12.9 42.4 0.077 12.6 21.7 2.4 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 KXX77836.1 - 0.13 12.4 0.0 0.13 12.4 0.0 4.7 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 YabA PF06156.13 KXX77836.1 - 2.1 9.0 7.5 1.7 9.4 0.2 2.7 2 0 0 2 2 2 0 Initiation control protein YabA Het-C PF07217.11 KXX77836.1 - 4.8 5.6 6.8 0.44 9.0 0.5 2.0 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Fungal_trans_2 PF11951.8 KXX77837.1 - 1.6e-18 66.7 0.0 2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 KXX77838.1 - 2.4e-07 31.2 0.3 0.00039 21.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX77838.1 - 2.3e-05 24.6 0.4 0.15 12.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXX77838.1 - 3.6e-05 24.0 2.4 0.034 14.5 0.2 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77838.1 - 0.00041 20.6 0.1 0.091 13.4 0.0 3.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KXX77838.1 - 0.0018 18.8 0.2 8.9 7.0 0.0 4.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Esterase_phd PF10503.9 KXX77840.1 - 1.7e-23 83.3 0.1 2.2e-23 82.9 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXX77840.1 - 1.5e-11 44.2 0.1 2.2e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXX77840.1 - 0.0055 16.6 0.0 0.0091 15.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXX77840.1 - 0.0056 16.4 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 KXX77840.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXX77840.1 - 0.019 14.7 0.1 0.066 13.0 0.1 2.0 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 KXX77840.1 - 0.021 14.4 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXX77840.1 - 0.023 14.3 0.6 0.045 13.4 0.5 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold PDZ_1 PF12812.7 KXX77841.1 - 4.1e-53 177.3 0.0 2.1e-34 117.4 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KXX77841.1 - 5.6e-26 92.2 1.1 2.2e-21 77.3 0.1 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KXX77841.1 - 1.8e-12 47.4 1.3 7.1e-05 23.1 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 KXX77841.1 - 1.9e-12 46.8 0.0 0.00062 19.6 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 KXX77841.1 - 6.3e-08 32.9 0.0 0.0065 16.8 0.0 3.9 4 0 0 4 4 4 1 PDZ domain Trypsin PF00089.26 KXX77841.1 - 0.00035 20.4 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 KXX77841.1 - 0.067 13.2 0.3 15 5.6 0.1 3.5 4 0 0 4 4 4 0 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KXX77841.1 - 0.075 12.8 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KXX77841.1 - 0.088 11.4 0.2 0.21 10.2 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 ADH_zinc_N PF00107.26 KXX77843.1 - 8.5e-18 64.6 0.3 1.3e-17 64.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX77843.1 - 1.2e-10 42.5 0.0 1.1e-09 39.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX77843.1 - 0.0097 15.8 0.0 0.039 13.8 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXX77843.1 - 0.15 11.5 1.2 0.39 10.2 0.8 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Ras PF00071.22 KXX77845.1 - 1.4e-54 184.1 0.9 4.8e-54 182.3 0.9 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXX77845.1 - 3.1e-20 72.6 0.0 4.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX77845.1 - 3e-09 36.6 0.1 3.6e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXX77845.1 - 1.6e-06 27.8 1.8 3.5e-06 26.7 0.1 2.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX77845.1 - 0.0019 18.3 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX77845.1 - 0.043 13.7 1.5 2.2 8.2 0.2 2.5 1 1 0 2 2 2 0 RsgA GTPase IstB_IS21 PF01695.17 KXX77845.1 - 0.11 12.2 0.5 2.3 7.9 0.1 2.8 2 1 1 3 3 3 0 IstB-like ATP binding protein MoCF_biosynth PF00994.24 KXX77846.1 - 6.5e-30 103.7 0.0 3e-29 101.5 0.0 1.9 2 1 0 2 2 2 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 KXX77847.1 - 4.9e-20 71.6 0.0 5.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Csm1 PF12539.8 KXX77847.1 - 0.082 13.6 0.6 0.19 12.3 0.4 1.7 1 1 1 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 ParA PF10609.9 KXX77848.1 - 2e-96 322.2 0.0 2.4e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXX77848.1 - 7.2e-09 35.8 0.0 2.9e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXX77848.1 - 1.1e-05 25.4 0.1 6.4e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KXX77848.1 - 1.8e-05 24.1 0.5 0.00025 20.3 0.1 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KXX77848.1 - 0.001 18.7 0.3 0.0019 17.8 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KXX77848.1 - 0.0012 18.7 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXX77848.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 KXX77848.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 KXX77848.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Fer4_NifH PF00142.18 KXX77848.1 - 0.0054 16.2 0.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 KXX77848.1 - 0.0068 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXX77848.1 - 0.0068 16.8 0.0 0.01 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain CBP_BcsQ PF06564.12 KXX77848.1 - 0.0071 15.9 0.1 0.079 12.4 0.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 KXX77848.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Ras PF00071.22 KXX77848.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Ras family RNA_helicase PF00910.22 KXX77848.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KXX77848.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 KXX77848.1 - 0.075 12.2 0.2 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 KXX77848.1 - 0.084 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXX77848.1 - 0.085 12.9 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KXX77848.1 - 0.085 12.9 0.1 6.1 7.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KXX77848.1 - 0.089 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 KXX77848.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KXX77848.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KXX77848.1 - 0.25 11.4 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ECM11 PF15463.6 KXX77849.1 - 1.2e-46 158.6 0.8 1.2e-46 158.6 0.8 2.4 2 1 1 3 3 3 1 Extracellular mutant protein 11 DUF3915 PF13054.6 KXX77849.1 - 0.28 11.2 7.3 0.6 10.1 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SRP54 PF00448.22 KXX77850.1 - 4.6e-07 29.7 0.0 6.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRK PF00485.18 KXX77850.1 - 4.9e-05 23.2 0.0 0.00011 22.0 0.0 1.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 KXX77850.1 - 0.00023 20.3 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXX77850.1 - 0.00024 21.5 0.1 0.0005 20.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXX77850.1 - 0.00038 19.8 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KXX77850.1 - 0.00049 20.6 0.0 0.0017 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXX77850.1 - 0.00093 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 KXX77850.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.4 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 KXX77850.1 - 0.0019 17.5 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.29 KXX77850.1 - 0.0022 18.4 0.0 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX77850.1 - 0.0029 17.8 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXX77850.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KXX77850.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXX77850.1 - 0.012 16.1 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXX77850.1 - 0.014 15.6 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KXX77850.1 - 0.015 15.2 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 KXX77850.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KXX77850.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 KXX77850.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 KXX77850.1 - 0.032 13.9 0.4 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 KXX77850.1 - 0.033 14.1 0.2 0.053 13.4 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 KXX77850.1 - 0.048 13.9 0.1 0.11 12.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KXX77850.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KXX77850.1 - 0.077 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LpxK PF02606.14 KXX77850.1 - 0.079 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF815 PF05673.13 KXX77850.1 - 0.085 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ArsA_ATPase PF02374.15 KXX77850.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase APS_kinase PF01583.20 KXX77850.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.6 KXX77850.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXX77850.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 adh_short PF00106.25 KXX77851.1 - 3.4e-86 287.7 11.0 2.1e-45 154.6 0.6 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX77851.1 - 4.2e-67 226.1 7.2 4.5e-35 121.3 0.5 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KXX77851.1 - 3.3e-34 117.1 0.0 6.4e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KXX77851.1 - 4.4e-31 108.2 3.4 4.6e-15 56.0 0.6 2.6 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 KXX77851.1 - 0.00032 20.8 0.0 0.38 10.9 0.0 2.8 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 KXX77851.1 - 0.00047 19.5 1.2 0.0091 15.3 0.6 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KXX77851.1 - 0.005 16.3 3.2 0.15 11.5 0.1 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXX77851.1 - 1.1 9.1 5.8 3.3 7.6 0.8 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 KXX77851.1 - 2.4 8.0 8.0 5.4 6.8 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase Ysc84 PF04366.12 KXX77852.1 - 1.3e-34 118.7 0.0 2.4e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator PAC2 PF09754.9 KXX77852.1 - 0.029 14.4 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 PAC2 family TrkA_TMD PF18613.1 KXX77852.1 - 0.12 11.8 0.8 0.34 10.4 0.8 1.7 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain SasG_E PF17041.5 KXX77853.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 E domain DUF459 PF04311.13 KXX77854.1 - 0.19 10.7 0.1 0.31 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) K_channel_TID PF07941.11 KXX77854.1 - 1.4 9.4 12.5 6.3 7.3 3.3 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Mit_KHE1 PF10173.9 KXX77855.1 - 9.1e-65 218.3 0.7 1.3e-64 217.8 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Cullin PF00888.22 KXX77857.1 - 1.5e-194 648.2 8.4 1.5e-194 648.2 8.4 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KXX77857.1 - 6.2e-26 90.2 5.9 6.2e-26 90.2 5.9 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 KXX77857.1 - 0.13 12.8 5.7 0.062 13.8 1.1 2.9 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal G-alpha PF00503.20 KXX77858.1 - 1e-113 380.2 0.4 1.2e-113 379.9 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXX77858.1 - 1.8e-15 56.8 0.3 5.3e-10 39.0 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXX77858.1 - 0.0001 21.7 0.3 0.06 12.7 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KXX77858.1 - 0.0023 18.1 0.1 0.98 9.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXX77858.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 KXX77859.1 - 0 1049.5 0.0 0 1049.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 KXX77860.1 - 3.2e-68 230.0 0.0 4e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77860.1 - 3.4e-32 111.7 0.0 4.5e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXX77860.1 - 9.4e-06 24.8 0.1 1.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXX77860.1 - 4.4e-05 22.9 0.1 0.00014 21.3 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX77860.1 - 0.00067 19.7 0.0 0.0019 18.2 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXX77860.1 - 0.001 18.4 0.0 0.036 13.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KXX77860.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KXX77860.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Avl9 PF09794.9 KXX77861.1 - 1.1e-144 481.8 0.0 1.5e-144 481.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KXX77861.1 - 2.4e-06 27.4 0.1 8.9e-05 22.2 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KXX77861.1 - 1.3e-05 25.1 0.0 0.00062 19.7 0.0 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis KH_8 PF17903.1 KXX77862.1 - 7e-30 103.0 0.0 1.9e-29 101.6 0.0 1.8 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KXX77862.1 - 0.034 14.0 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 KH domain Pfg27 PF09216.10 KXX77862.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Pfg27 Ribosomal_60s PF00428.19 KXX77862.1 - 0.49 11.0 6.9 0.97 10.1 6.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein GATA PF00320.27 KXX77863.1 - 7.2e-15 54.3 3.0 1.2e-14 53.6 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger ATG16 PF08614.11 KXX77863.1 - 0.00034 20.9 15.4 0.00034 20.9 15.4 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KXX77863.1 - 0.0005 20.6 13.7 0.001 19.6 13.7 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region FapA PF03961.13 KXX77863.1 - 0.0052 15.4 5.1 0.0071 15.0 5.1 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A LMBR1 PF04791.16 KXX77863.1 - 0.0068 15.4 1.0 0.0084 15.1 1.0 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4226 PF10774.9 KXX77863.1 - 0.0076 16.5 4.7 0.023 14.9 4.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4226) TF_Zn_Ribbon PF08271.12 KXX77863.1 - 0.0097 15.4 0.4 0.018 14.5 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding UBA_e1_thiolCys PF10585.9 KXX77863.1 - 0.018 15.0 0.7 0.028 14.4 0.7 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF3584 PF12128.8 KXX77863.1 - 0.038 11.5 15.8 0.055 11.0 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tho2 PF11262.8 KXX77863.1 - 0.082 12.1 9.7 0.14 11.4 9.7 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Macoilin PF09726.9 KXX77863.1 - 0.098 11.2 7.5 0.12 10.9 7.5 1.2 1 0 0 1 1 1 0 Macoilin family CLZ PF16526.5 KXX77863.1 - 0.11 12.9 14.3 0.37 11.2 10.9 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Auto_anti-p27 PF06677.12 KXX77863.1 - 0.19 11.9 0.6 0.31 11.2 0.6 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Fmp27_WPPW PF10359.9 KXX77863.1 - 0.36 9.6 10.2 0.55 9.0 10.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ArfGap PF01412.18 KXX77863.1 - 0.37 10.9 2.3 0.63 10.1 0.0 2.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Pox_A_type_inc PF04508.12 KXX77863.1 - 0.45 10.5 5.9 19 5.3 0.0 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 KXX77863.1 - 1.2 7.9 18.7 2 7.2 18.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein JIP_LZII PF16471.5 KXX77863.1 - 2.1 8.6 15.7 0.43 10.8 5.9 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Atg14 PF10186.9 KXX77863.1 - 2.2 7.3 15.4 3.1 6.8 14.1 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 KXX77863.1 - 3.4 7.7 27.0 0.59 10.2 7.6 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 KXX77863.1 - 4.2 5.2 7.4 5.6 4.7 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family INCENP_ARK-bind PF03941.15 KXX77864.1 - 2.2e-19 69.1 0.4 2.2e-19 69.1 0.4 2.7 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region IF-2B PF01008.17 KXX77864.1 - 1.5 7.9 6.5 0.095 11.9 0.2 2.0 2 0 0 2 2 2 0 Initiation factor 2 subunit family AAA_23 PF13476.6 KXX77864.1 - 4.5 7.7 23.4 11 6.4 7.8 2.6 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.31 KXX77865.1 - 9.4e-19 67.3 0.4 9.4e-19 67.3 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain Snf7 PF03357.21 KXX77866.1 - 4.1e-18 65.6 14.3 6.2e-18 65.0 14.3 1.3 1 0 0 1 1 1 1 Snf7 PDH_E1_M PF17831.1 KXX77866.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain Phage_int_SAM_1 PF02899.17 KXX77866.1 - 0.17 12.2 2.5 0.86 9.9 1.4 2.7 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain SPOB_a PF14689.6 KXX77866.1 - 0.35 10.6 1.7 5 6.9 0.0 3.1 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain DnaI_N PF07319.11 KXX77866.1 - 0.55 10.9 2.1 11 6.8 0.3 2.6 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Mrr_N PF14338.6 KXX77866.1 - 2.6 8.2 5.6 6.4 7.0 0.1 3.5 4 1 0 4 4 4 0 Mrr N-terminal domain DUF948 PF06103.11 KXX77866.1 - 3.2 8.1 6.9 1.8e+02 2.5 6.9 2.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Muted PF14942.6 KXX77866.1 - 9.2 6.6 13.1 0.79 10.1 1.1 2.9 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein zf-C3HC4_2 PF13923.6 KXX77867.1 - 1.4e-10 40.8 16.9 2.9e-10 39.8 13.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 KXX77867.1 - 2e-07 30.6 0.1 3.4e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.25 KXX77867.1 - 1e-06 28.5 14.1 1e-06 28.5 14.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX77867.1 - 1.2e-05 25.1 11.0 1.2e-05 25.1 11.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX77867.1 - 1.6e-05 24.8 11.7 1.6e-05 24.8 11.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 KXX77867.1 - 3.2e-05 23.7 7.3 5.9e-05 22.8 5.6 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KXX77867.1 - 7.5e-05 22.6 13.0 7.5e-05 22.6 13.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXX77867.1 - 0.0002 21.6 19.7 0.00047 20.4 14.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXX77867.1 - 0.0011 19.0 13.5 0.0011 19.0 13.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXX77867.1 - 0.0014 18.4 14.5 0.019 14.8 11.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 KXX77867.1 - 0.0015 18.7 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_10 PF16685.5 KXX77867.1 - 0.0024 17.9 5.6 0.0048 17.0 5.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KXX77867.1 - 0.0029 17.9 8.2 0.0029 17.9 8.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Mob_synth_C PF06463.13 KXX77867.1 - 0.059 13.3 2.9 0.13 12.1 2.9 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-RING_4 PF14570.6 KXX77867.1 - 0.66 9.8 14.2 0.084 12.7 4.8 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXX77867.1 - 2.5 8.2 6.7 1.1 9.4 4.0 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 KXX77867.1 - 9.5 6.0 15.3 3.3 7.4 9.8 2.3 2 0 0 2 2 2 0 P-11 zinc finger Tyr_Deacylase PF02580.16 KXX77868.1 - 1.7e-52 177.7 0.1 2e-52 177.5 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 KXX77869.1 - 6.4e-90 300.6 25.0 6.4e-90 300.6 25.0 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KXX77869.1 - 1.8e-42 144.5 9.4 4.3e-42 143.3 9.4 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KXX77869.1 - 0.0049 17.2 4.7 0.0049 17.2 4.7 2.5 3 0 0 3 3 2 1 Syntaxin-like protein ABC_tran_CTD PF16326.5 KXX77869.1 - 0.007 16.6 6.8 0.007 16.6 6.8 3.4 2 1 0 2 2 1 1 ABC transporter C-terminal domain Snapin_Pallidin PF14712.6 KXX77869.1 - 0.0072 16.7 0.5 0.0072 16.7 0.5 2.8 2 1 1 3 3 3 1 Snapin/Pallidin DUF2373 PF10180.9 KXX77869.1 - 0.014 15.3 2.8 0.032 14.1 2.8 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) HR1 PF02185.16 KXX77869.1 - 0.028 14.5 1.8 0.028 14.5 1.8 3.0 3 0 0 3 3 3 0 Hr1 repeat Cep57_MT_bd PF06657.13 KXX77869.1 - 0.042 14.3 13.1 0.38 11.2 2.6 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.11 KXX77869.1 - 0.069 13.2 7.5 0.079 13.0 3.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Sec5 PF15469.6 KXX77869.1 - 0.3 10.9 10.5 0.17 11.7 1.6 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 4HB_MCP_1 PF12729.7 KXX77869.1 - 2 7.9 15.3 0.64 9.5 9.1 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction CorA PF01544.18 KXX77869.1 - 6.9 5.9 9.0 0.76 9.0 1.9 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF908 PF06012.12 KXX77870.1 - 0.0073 15.8 3.2 0.0089 15.5 3.2 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) CFEM PF05730.11 KXX77870.1 - 1.1 9.4 12.1 4.9 7.3 12.1 2.2 1 1 0 1 1 1 0 CFEM domain Hamartin PF04388.12 KXX77870.1 - 5.8 5.5 7.4 6.9 5.2 7.4 1.0 1 0 0 1 1 1 0 Hamartin protein RAP1 PF07218.11 KXX77870.1 - 6.3 4.9 6.7 7.7 4.7 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MGC-24 PF05283.11 KXX77870.1 - 7 7.1 18.2 20 5.6 17.5 1.8 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-RING_UBOX PF13445.6 KXX77871.1 - 8.2e-08 32.2 2.4 8.2e-08 32.2 2.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXX77871.1 - 5.6e-07 29.3 6.4 1e-06 28.5 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX77871.1 - 8.2e-07 28.8 5.0 1.6e-06 27.8 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX77871.1 - 1.2e-06 28.8 6.7 2.3e-06 27.9 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX77871.1 - 2.4e-06 27.3 5.4 5.8e-06 26.0 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX77871.1 - 8.5e-06 25.6 4.7 1.8e-05 24.6 4.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXX77871.1 - 6.5e-05 23.0 5.8 0.00037 20.6 5.8 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXX77871.1 - 0.0088 15.9 9.2 0.047 13.6 8.8 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 PRP1_N PF06424.12 KXX77871.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.4 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal zf-rbx1 PF12678.7 KXX77871.1 - 0.5 10.7 6.9 1.8 8.9 6.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ribbon_3 PF13248.6 KXX77871.1 - 0.51 9.8 3.9 5.4 6.6 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-MIZ PF02891.20 KXX77871.1 - 0.6 9.9 8.1 7.1 6.5 8.2 2.3 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger TerY_C PF15616.6 KXX77871.1 - 0.7 10.0 2.8 1.9 8.6 2.8 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING_10 PF16685.5 KXX77871.1 - 1 9.5 5.8 2.6 8.2 5.8 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 Lar_restr_allev PF14354.6 KXX77871.1 - 5.6 7.4 5.8 1 9.8 1.3 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar 2OG-FeII_Oxy_3 PF13640.6 KXX77873.1 - 1.6e-06 28.9 0.0 2.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.6 KXX77874.1 - 1.7e-21 76.9 0.0 7.7e-19 68.3 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KXX77874.1 - 3.6e-06 26.9 0.0 2.5e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin T2SSE_N PF05157.15 KXX77874.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Ino80_Iec3 PF14612.6 KXX77875.1 - 1.1e-56 193.2 2.5 3.6e-28 99.8 1.2 2.2 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling AAA PF00004.29 KXX77876.1 - 1.3e-19 70.9 0.0 2.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXX77876.1 - 3.7e-05 23.7 0.0 9.5e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXX77876.1 - 0.00026 21.4 0.0 0.00068 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zot PF05707.12 KXX77876.1 - 0.00049 19.8 0.1 0.0056 16.3 0.0 2.2 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_2 PF07724.14 KXX77876.1 - 0.00087 19.4 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXX77876.1 - 0.004 17.4 0.1 0.045 14.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KXX77876.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 KXX77876.1 - 0.025 14.0 0.1 0.058 12.7 0.1 1.5 1 1 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 KXX77876.1 - 0.027 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXX77876.1 - 0.051 13.1 0.1 0.15 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXX77876.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXX77876.1 - 0.095 13.2 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KXX77876.1 - 0.13 12.4 0.0 9.2 6.4 0.0 2.3 1 1 1 2 2 2 0 Torsin Sigma54_activat PF00158.26 KXX77876.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KXX77876.1 - 0.16 11.0 0.0 0.57 9.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein TIP49 PF06068.13 KXX77876.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Lzipper-MIP1 PF14389.6 KXX77877.1 - 0.013 15.7 4.3 0.18 12.1 0.4 3.1 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Ge1_WD40 PF16529.5 KXX77877.1 - 0.027 13.4 0.0 0.17 10.8 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lectin_N PF03954.14 KXX77877.1 - 0.13 12.0 1.8 0.61 9.8 0.2 2.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Spc24 PF08286.11 KXX77877.1 - 0.18 12.1 3.9 0.96 9.7 0.9 3.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 KXX77877.1 - 4.9 7.2 6.4 2.1 8.4 1.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RasGAP PF00616.19 KXX77878.1 - 3.4e-31 108.6 0.0 3.2e-22 79.3 0.0 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KXX77878.1 - 0.00016 21.9 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pro_isomerase PF00160.21 KXX77879.1 - 5.8e-49 166.4 0.1 8.5e-49 165.9 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KXX77879.1 - 1.6e-06 27.7 3.0 0.00034 20.5 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX77879.1 - 0.00019 21.1 0.9 0.00058 19.6 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX77879.1 - 0.0018 18.4 0.1 0.0056 16.8 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX77879.1 - 0.002 18.4 0.4 0.0067 16.7 0.2 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXX77879.1 - 0.0045 17.1 1.0 0.011 15.9 1.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXX77879.1 - 0.0081 15.8 1.6 2.6 7.8 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 KXX77879.1 - 0.015 15.9 1.7 0.015 15.9 1.7 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX77879.1 - 0.036 14.7 1.3 0.11 13.1 0.2 2.6 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX77879.1 - 0.044 14.6 3.8 0.1 13.4 1.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXX77879.1 - 0.075 13.6 3.4 0.12 12.9 2.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KXX77879.1 - 0.095 12.6 0.3 0.15 11.9 0.3 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal NmrA PF05368.13 KXX77880.1 - 3.8e-51 173.9 0.7 4.5e-51 173.7 0.7 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX77880.1 - 2.8e-11 43.7 0.5 4.4e-11 43.0 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HET PF06985.11 KXX77881.1 - 8.8e-25 87.8 0.0 1.7e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 KXX77882.1 - 6.4e-55 186.3 0.0 9.2e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXX77882.1 - 1.9e-11 43.7 12.8 6.2e-11 42.1 12.8 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain AltA1 PF16541.5 KXX77883.1 - 3.6e-24 85.8 0.8 4.8e-24 85.3 0.8 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 AMPK1_CBM PF16561.5 KXX77884.1 - 3.4e-22 78.5 0.9 6.6e-22 77.5 0.9 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KXX77884.1 - 0.027 14.8 0.2 0.06 13.7 0.2 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) NAD_binding_6 PF08030.12 KXX77885.1 - 2.9e-21 76.2 0.0 4.8e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXX77885.1 - 3.4e-15 56.3 7.7 3.4e-15 56.3 7.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXX77885.1 - 6.1e-10 39.2 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 KXX77885.1 - 0.0085 16.6 2.3 0.0085 16.6 2.3 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF4405) Gaa1 PF04114.14 KXX77885.1 - 0.04 13.0 6.5 0.055 12.5 6.5 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component SLD3 PF08639.10 KXX77885.1 - 0.13 11.0 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Iso_dh PF00180.20 KXX77886.1 - 3.3e-70 236.9 0.0 4e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2 PF00096.26 KXX77887.1 - 0.063 13.8 17.7 0.36 11.4 0.2 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type UPF0160 PF03690.13 KXX77888.1 - 5e-130 433.8 0.0 5.7e-130 433.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF5127 PF17168.4 KXX77889.1 - 4.9e-92 307.8 7.7 7.6e-92 307.2 7.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KXX77889.1 - 3.1e-72 241.8 1.2 8.1e-72 240.5 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KXX77889.1 - 4.2e-62 209.5 0.1 1.1e-61 208.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXX77889.1 - 1.4e-06 27.8 1.7 2.4e-06 27.0 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4964) Endosulfine PF04667.17 KXX77890.1 - 3.1e-28 97.7 0.0 7.4e-28 96.5 0.0 1.7 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DivIC PF04977.15 KXX77891.1 - 0.0049 16.6 0.5 0.015 15.1 0.5 1.7 1 0 0 1 1 1 1 Septum formation initiator YabA PF06156.13 KXX77891.1 - 0.05 14.3 2.3 0.13 12.9 2.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA TolA_bind_tri PF16331.5 KXX77891.1 - 0.056 13.5 1.9 0.14 12.3 1.9 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Macoilin PF09726.9 KXX77891.1 - 0.27 9.7 10.9 0.43 9.1 10.9 1.2 1 0 0 1 1 1 0 Macoilin family Prominin PF05478.11 KXX77891.1 - 0.37 8.7 0.2 0.54 8.1 0.2 1.2 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 KXX77891.1 - 4.7 6.5 7.2 0.82 9.0 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PGAP1 PF07819.13 KXX77892.1 - 3.3e-08 33.6 0.0 5.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KXX77892.1 - 8.2e-08 32.4 0.0 1.1e-07 32.0 0.0 1.3 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KXX77892.1 - 8.5e-07 28.9 0.1 3.3e-06 26.9 0.1 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 KXX77892.1 - 1.5e-06 27.9 0.1 3.9e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KXX77892.1 - 5.7e-06 27.1 0.5 8e-06 26.6 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 KXX77892.1 - 2.7e-05 23.5 0.0 4.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 KXX77892.1 - 0.0057 16.8 0.0 0.0094 16.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_2 PF01674.18 KXX77892.1 - 0.0092 15.5 0.0 0.11 12.0 0.0 2.3 3 0 0 3 3 3 1 Lipase (class 2) Hydrolase_4 PF12146.8 KXX77892.1 - 0.014 14.6 0.2 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KXX77892.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 KXX77892.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase DUF915 PF06028.11 KXX77892.1 - 0.21 10.9 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Arrestin_N PF00339.29 KXX77893.1 - 1.1e-15 57.9 0.0 2.1e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXX77893.1 - 3.9e-05 24.1 0.0 0.00033 21.1 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MRP_L53 PF10780.9 KXX77894.1 - 1.1e-21 76.8 0.2 1.6e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 KXX77895.1 - 6.1e-16 58.1 0.7 1.7e-15 56.7 0.1 2.0 2 0 0 2 2 2 1 Sec20 FapA PF03961.13 KXX77895.1 - 0.11 11.1 0.4 0.48 9.0 0.2 1.9 2 1 0 2 2 2 0 Flagellar Assembly Protein A ANAPC4_WD40 PF12894.7 KXX77897.1 - 8.3e-07 29.2 0.1 0.44 10.9 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX77897.1 - 0.0077 17.1 9.1 14 6.8 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF2583 PF10762.9 KXX77897.1 - 0.14 12.6 0.2 0.46 10.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) ArfGap PF01412.18 KXX77898.1 - 2.8e-34 117.7 0.5 1e-33 115.9 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KXX77898.1 - 1.7e-22 80.3 15.7 2.8e-22 79.6 15.7 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KXX77898.1 - 8.8e-13 48.7 0.1 2.1e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 PH domain PilJ PF13675.6 KXX77898.1 - 0.017 15.1 0.4 0.017 15.1 0.4 2.4 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term tRNA-synt_2 PF00152.20 KXX77898.1 - 0.043 12.9 1.7 0.072 12.2 1.7 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) AAA_24 PF13479.6 KXX77898.1 - 0.043 13.5 0.1 0.084 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_C27 PF05407.12 KXX77898.1 - 0.39 10.8 3.3 0.17 11.9 0.3 1.9 2 0 0 2 2 2 0 Rubella virus endopeptidase DUF2115 PF09888.9 KXX77898.1 - 0.46 11.0 2.6 1.2 9.6 2.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) EMP24_GP25L PF01105.24 KXX77898.1 - 0.49 10.3 2.5 3.7 7.5 1.1 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PH_9 PF15410.6 KXX77898.1 - 3.2 8.1 5.6 1.3 9.4 1.0 2.6 2 1 0 2 2 1 0 Pleckstrin homology domain CP12 PF02672.15 KXX77898.1 - 4.2 8.2 7.2 0.23 12.2 0.5 2.4 3 0 0 3 3 2 0 CP12 domain Pkinase PF00069.25 KXX77899.1 - 8.6e-77 258.1 0.0 1.1e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX77899.1 - 3.9e-37 127.9 0.0 5.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KXX77899.1 - 8.4e-16 58.1 0.1 1.8e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KXX77899.1 - 3.1e-10 39.9 0.0 5.9e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Yop-YscD_cpl PF16697.5 KXX77899.1 - 6.3e-07 29.6 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KXX77899.1 - 2.4e-06 26.6 0.0 3.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXX77899.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXX77899.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KXX77899.1 - 0.12 12.0 0.0 15 5.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 KXX77899.1 - 0.13 11.2 0.1 0.46 9.4 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pyrophosphatase PF00719.19 KXX77900.1 - 3.6e-57 192.6 0.2 4.8e-57 192.2 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Membr_traf_MHD PF10540.9 KXX77901.1 - 1.7e-18 67.2 0.2 3.3e-10 40.3 0.5 3.0 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KXX77901.1 - 4.1e-17 62.4 0.0 1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KXX77901.1 - 0.00047 18.9 0.2 0.0011 17.6 0.2 1.7 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) Baculo_VP91_N PF08475.10 KXX77901.1 - 0.00071 19.3 0.1 0.85 9.3 0.0 2.6 2 0 0 2 2 2 2 Viral capsid protein 91 N-terminal ADK PF00406.22 KXX77902.1 - 2.9e-44 150.8 0.0 4.1e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXX77902.1 - 4.1e-35 121.2 0.0 6.2e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXX77902.1 - 1.2e-07 32.3 0.0 1.8e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXX77902.1 - 7.8e-05 22.9 0.4 0.00021 21.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KXX77902.1 - 0.016 14.9 0.0 0.86 9.3 0.0 2.2 1 1 1 2 2 2 0 Thymidylate kinase CAP_N PF01213.19 KXX77902.1 - 2.4 7.5 5.5 3.8 6.9 5.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cation_efflux PF01545.21 KXX77903.1 - 0.2 11.4 2.7 0.65 9.7 2.7 1.8 1 1 0 1 1 1 0 Cation efflux family DUF202 PF02656.15 KXX77903.1 - 0.22 12.0 5.7 5 7.6 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Vpu PF00558.19 KXX77903.1 - 1.6 8.6 6.8 2.9 7.7 1.7 2.4 2 0 0 2 2 2 0 Vpu protein DUF2569 PF10754.9 KXX77903.1 - 3.3 8.1 7.6 1 9.8 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) TPR_2 PF07719.17 KXX77904.1 - 7.9e-06 25.6 2.2 0.17 12.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX77904.1 - 2.2e-05 24.0 1.5 0.0052 16.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX77904.1 - 0.0006 20.0 0.4 0.0014 18.8 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KXX77904.1 - 0.00094 19.8 0.9 0.0034 18.0 0.0 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KXX77904.1 - 0.015 15.3 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_19 PF14559.6 KXX77904.1 - 0.018 15.6 0.0 0.22 12.1 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 KXX77904.1 - 0.054 13.9 0.0 0.25 11.7 0.0 1.9 1 1 0 1 1 1 0 SET domain PCI PF01399.27 KXX77905.1 - 3.2e-14 53.3 0.2 4e-13 49.8 0.1 2.4 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KXX77905.1 - 6.1e-05 22.6 0.2 6.1e-05 22.6 0.2 1.9 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix DUF3939 PF13075.6 KXX77905.1 - 0.045 13.8 0.6 0.96 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) DUF4363 PF14276.6 KXX77905.1 - 2 8.5 5.0 9.4 6.4 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) eIF2_C PF09173.11 KXX77906.1 - 5.5e-35 119.5 0.5 1.3e-34 118.3 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KXX77906.1 - 7.9e-23 81.0 0.5 3.4e-22 78.9 0.5 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXX77906.1 - 3.3e-10 40.2 0.1 7.1e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXX77906.1 - 0.0033 17.5 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ProQ_C PF17516.2 KXX77906.1 - 0.0038 16.6 1.9 0.009 15.4 1.9 1.7 1 0 0 1 1 1 1 ProQ C-terminal domain MMR_HSR1_Xtn PF16897.5 KXX77906.1 - 0.0083 16.1 1.3 0.02 14.9 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KXX77906.1 - 0.034 14.1 0.3 0.36 10.7 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF5102 PF17104.5 KXX77907.1 - 1.8e-88 297.4 8.7 2e-56 192.2 6.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5102) 14-3-3 PF00244.20 KXX77908.1 - 4.3e-102 340.3 2.1 8.1e-102 339.4 2.1 1.4 1 1 0 1 1 1 1 14-3-3 protein Mito_carr PF00153.27 KXX77909.1 - 2.3e-60 200.5 0.0 4.9e-21 74.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KfrA_N PF11740.8 KXX77909.1 - 0.05 14.3 0.7 0.12 13.1 0.7 1.6 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term TspO_MBR PF03073.15 KXX77910.1 - 3.9e-37 127.3 7.7 6.2e-37 126.7 7.7 1.3 1 0 0 1 1 1 1 TspO/MBR family IATP PF04568.12 KXX77911.1 - 7.3e-31 106.5 0.4 8.2e-31 106.3 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.12 KXX77911.1 - 0.041 13.9 0.3 0.048 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF2205 PF10224.9 KXX77911.1 - 0.13 12.3 4.2 0.18 11.8 4.2 1.2 1 0 0 1 1 1 0 Short coiled-coil protein Nsp1_C PF05064.13 KXX77912.1 - 2.9e-43 146.3 3.5 6.6e-43 145.2 3.5 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF948 PF06103.11 KXX77912.1 - 0.0088 16.3 0.9 0.15 12.3 0.1 2.8 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 KXX77912.1 - 0.018 14.0 6.2 0.13 11.1 1.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF2935 PF11155.8 KXX77912.1 - 0.03 14.6 0.1 3 8.2 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 KXX77912.1 - 0.035 14.1 3.0 5 7.2 0.6 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SGT1 PF07093.11 KXX77912.1 - 0.042 12.3 2.9 0.055 11.9 2.9 1.1 1 0 0 1 1 1 0 SGT1 protein Med30 PF11315.8 KXX77912.1 - 0.05 13.8 2.5 0.1 12.8 2.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 30 MIP-T3_C PF17749.1 KXX77912.1 - 0.071 13.1 5.3 0.28 11.2 0.1 3.0 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Nup88 PF10168.9 KXX77912.1 - 0.15 9.9 4.4 0.19 9.5 4.4 1.1 1 0 0 1 1 1 0 Nuclear pore component EzrA PF06160.12 KXX77912.1 - 0.23 9.6 7.3 2.1 6.4 6.8 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Flagellar_rod PF05149.12 KXX77912.1 - 0.31 10.5 4.5 0.87 9.0 4.4 1.7 1 1 0 1 1 1 0 Paraflagellar rod protein DUF1664 PF07889.12 KXX77912.1 - 0.39 10.8 3.9 16 5.6 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) XhlA PF10779.9 KXX77912.1 - 0.54 10.5 6.7 3.2 8.0 0.5 3.2 2 1 1 3 3 3 0 Haemolysin XhlA Mer2 PF09074.10 KXX77912.1 - 0.65 9.8 4.3 4 7.2 0.1 2.1 2 0 0 2 2 2 0 Mer2 HIP1_clath_bdg PF16515.5 KXX77912.1 - 0.71 10.5 6.2 17 6.1 0.1 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4200 PF13863.6 KXX77912.1 - 0.84 10.1 8.3 0.34 11.3 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DHR10 PF18595.1 KXX77912.1 - 1.6 8.8 8.4 5.5 7.1 3.1 2.4 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain TACC_C PF05010.14 KXX77912.1 - 1.7 8.4 10.1 1.6 8.5 8.0 1.9 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3450 PF11932.8 KXX77912.1 - 1.9 7.7 9.5 2.8 7.2 5.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) OmpH PF03938.14 KXX77912.1 - 2 8.8 11.6 3.9 7.8 0.3 2.7 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 KXX77912.1 - 2.1 8.3 7.5 1.8 8.6 0.9 2.8 2 1 0 2 2 2 0 Prefoldin subunit MscS_porin PF12795.7 KXX77912.1 - 2.5 7.6 10.9 1.6 8.2 4.5 2.2 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain KxDL PF10241.9 KXX77912.1 - 3.1 8.1 7.2 95 3.4 1.3 3.5 1 1 3 4 4 4 0 Uncharacterized conserved protein DUF16 PF01519.16 KXX77912.1 - 4.9 7.7 5.9 29 5.2 3.8 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Nucleoporin_FG PF13634.6 KXX77912.1 - 5.4 7.9 173.6 0.16 12.8 33.2 7.8 2 1 6 8 8 6 0 Nucleoporin FG repeat region Mitoc_mL59 PF18126.1 KXX77913.1 - 1e-44 152.0 4.5 1e-44 152.0 4.5 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 KXX77913.1 - 2.8e-17 62.2 0.0 4.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KXX77913.1 - 1.3e-05 25.2 5.2 0.021 14.9 0.4 2.8 3 0 0 3 3 3 2 DnaJ domain TFIIA PF03153.13 KXX77913.1 - 0.0098 15.9 23.7 0.014 15.5 23.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 KXX77914.1 - 4.6e-39 133.9 0.4 7e-39 133.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX77914.1 - 6.4e-26 91.4 0.3 8.9e-26 90.9 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX77914.1 - 1.5e-09 38.0 5.5 5.3e-08 33.0 5.5 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX77914.1 - 2.6e-06 27.1 0.2 1.1e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX77914.1 - 0.00021 21.2 0.4 0.00048 20.1 0.3 1.7 2 1 0 2 2 2 1 NAD(P)H-binding FtsJ PF01728.19 KXX77914.1 - 0.0017 18.5 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase RmlD_sub_bind PF04321.17 KXX77914.1 - 0.002 17.3 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXX77914.1 - 0.0028 17.1 0.1 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase UPF0146 PF03686.13 KXX77914.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DUF3216 PF11505.8 KXX77914.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) 3HCDH_N PF02737.18 KXX77914.1 - 0.037 13.9 0.8 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXX77914.1 - 0.044 12.8 0.1 0.065 12.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KXX77914.1 - 0.077 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 KXX77914.1 - 2.2 7.3 4.2 0.6 9.2 0.4 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 KXX77915.1 - 2.3e-59 201.4 0.0 3.1e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXX77915.1 - 2.6e-29 102.4 0.0 4.7e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Ank_2 PF12796.7 KXX77916.1 - 2.7e-17 63.1 0.0 3.1e-07 30.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX77916.1 - 1e-15 57.4 4.2 9.9e-06 25.8 0.0 4.5 5 0 0 5 5 4 3 Ankyrin repeat Ank_4 PF13637.6 KXX77916.1 - 2.5e-15 56.6 0.1 3.2e-10 40.3 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX77916.1 - 2.3e-13 50.1 0.1 1.6e-09 37.9 0.1 3.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) HET PF06985.11 KXX77916.1 - 7.8e-11 42.5 7.4 1.2e-08 35.4 0.1 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 KXX77916.1 - 3.7e-08 33.0 0.1 0.25 12.0 0.0 4.6 5 0 0 5 5 4 2 Ankyrin repeat KASH_CCD PF14662.6 KXX77916.1 - 0.0085 15.9 6.2 0.014 15.2 6.2 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KXX77916.1 - 0.024 14.4 1.8 0.054 13.3 1.8 1.6 1 0 0 1 1 1 0 Septum formation initiator CENP-F_leu_zip PF10473.9 KXX77916.1 - 0.028 14.5 7.1 0.058 13.4 7.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 KXX77916.1 - 0.038 13.7 4.5 0.059 13.1 4.5 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 KXX77916.1 - 0.11 12.6 4.3 0.24 11.5 4.3 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KXX77916.1 - 0.18 11.9 1.2 0.88 9.6 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 KXX77916.1 - 0.19 10.3 2.6 0.28 9.8 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 KXX77916.1 - 0.25 10.2 6.8 0.41 9.5 6.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 KXX77916.1 - 0.36 11.5 4.5 0.82 10.3 4.5 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Atg14 PF10186.9 KXX77916.1 - 0.73 8.9 5.0 1.1 8.3 5.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KXX77916.1 - 0.73 9.6 4.4 1.3 8.8 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KXX77916.1 - 1.4 9.0 4.7 2.4 8.2 4.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KXX77916.1 - 1.9 9.0 7.2 5.4 7.5 6.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB F-box PF00646.33 KXX77917.1 - 1.2e-06 28.3 1.9 2.7e-06 27.1 1.9 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX77917.1 - 3e-06 27.0 0.7 1.2e-05 25.1 0.7 2.1 1 0 0 1 1 1 1 F-box-like DUF4091 PF13320.6 KXX77917.1 - 0.39 10.9 1.5 1.1 9.4 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) Indigoidine_A PF04227.12 KXX77919.1 - 1.1e-111 372.8 0.2 2e-111 372.0 0.2 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KXX77919.1 - 7e-23 81.4 0.3 1.1e-13 51.2 0.0 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Neur_chan_memb PF02932.16 KXX77920.1 - 0.2 11.7 0.3 0.26 11.3 0.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mlh1_C PF16413.5 KXX77921.1 - 9e-104 346.6 0.0 1.5e-103 345.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KXX77921.1 - 3.5e-34 117.0 0.1 5.7e-34 116.3 0.1 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXX77921.1 - 3.9e-11 42.9 0.0 7.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXX77921.1 - 1.2e-07 32.2 0.0 2.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lon_C PF05362.13 KXX77922.1 - 1.3e-67 227.3 0.3 2.4e-67 226.5 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXX77922.1 - 1e-23 84.3 0.0 1.8e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXX77922.1 - 1.5e-23 83.7 0.0 4e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXX77922.1 - 1.4e-10 41.3 0.0 4.5e-10 39.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KXX77922.1 - 5.2e-07 29.5 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KXX77922.1 - 2.8e-06 27.8 0.0 9.4e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KXX77922.1 - 2.7e-05 24.0 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KXX77922.1 - 8.3e-05 22.5 0.0 0.00023 21.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX77922.1 - 0.00019 21.7 0.0 0.0073 16.6 0.0 3.0 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 KXX77922.1 - 0.00032 20.9 0.0 0.00097 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXX77922.1 - 0.00036 20.3 0.1 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXX77922.1 - 0.0021 17.3 0.1 0.0045 16.3 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KXX77922.1 - 0.0031 17.7 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXX77922.1 - 0.019 14.6 0.1 0.044 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXX77922.1 - 0.021 14.9 0.0 0.067 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXX77922.1 - 0.036 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXX77922.1 - 0.041 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX77922.1 - 0.042 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KXX77922.1 - 0.045 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KXX77922.1 - 0.047 14.2 3.1 0.14 12.6 0.0 2.6 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXX77922.1 - 0.079 12.3 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXX77922.1 - 0.088 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KXX77922.1 - 0.089 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 KXX77922.1 - 0.092 12.6 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 KXX77922.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_PrkA PF08298.11 KXX77922.1 - 0.18 10.7 0.0 1.6 7.6 0.1 2.0 2 0 0 2 2 2 0 PrkA AAA domain SOAR PF16533.5 KXX77922.1 - 0.87 9.6 2.5 0.67 10.0 0.1 2.0 2 0 0 2 2 1 0 STIM1 Orai1-activating region FAD_binding_1 PF00667.20 KXX77924.1 - 1.9e-62 210.8 0.0 2.7e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXX77924.1 - 4e-35 121.1 0.3 8.3e-35 120.1 0.3 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXX77924.1 - 4.8e-19 69.0 0.0 2.8e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXX77924.1 - 0.025 14.8 0.1 0.086 13.1 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.6 KXX77925.1 - 6.3e-223 741.7 0.0 1.1e-222 740.9 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KXX77925.1 - 3.5e-95 318.7 0.9 3.5e-95 318.7 0.9 2.4 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KXX77925.1 - 2.2e-37 128.3 4.7 6.2e-16 57.3 0.1 3.8 2 1 1 3 3 3 3 Cell morphogenesis central region DUF759 PF05537.11 KXX77925.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) RIO1 PF01163.22 KXX77926.1 - 9.3e-41 139.5 0.1 2.3e-40 138.2 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KXX77926.1 - 2.2e-33 114.3 0.0 5.2e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 KXX77926.1 - 1.9e-06 27.4 0.0 0.0072 15.7 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX77926.1 - 1.4e-05 25.1 5.5 0.0049 16.8 0.2 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family NOA36 PF06524.12 KXX77926.1 - 1.1 8.6 13.2 1.5 8.1 13.2 1.1 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 KXX77926.1 - 2.9 7.6 9.1 5 6.9 9.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 KXX77926.1 - 4.2 6.7 8.6 7.4 5.9 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 KXX77926.1 - 9.6 4.3 17.1 13 3.9 17.1 1.1 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.22 KXX77927.1 - 6.1e-26 90.0 0.0 2.4e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec1 PF00995.23 KXX77928.1 - 1.3e-120 404.3 0.0 1.5e-120 404.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RPN1_RPN2_N PF17781.1 KXX77929.1 - 1.7e-113 379.1 0.3 3.2e-113 378.2 0.3 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KXX77929.1 - 5.1e-30 103.3 0.0 9e-30 102.5 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KXX77929.1 - 7.6e-26 89.2 15.1 1.8e-07 31.2 0.1 9.0 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXX77929.1 - 3e-08 33.9 2.0 0.00015 22.1 0.0 3.9 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KXX77929.1 - 0.1 13.1 0.9 5.8 7.5 0.1 3.3 1 1 1 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KXX77929.1 - 0.12 12.7 0.0 31 5.2 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Pinin_SDK_memA PF04696.13 KXX77929.1 - 0.2 11.7 3.1 0.41 10.7 3.1 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region AbbA_antirepres PF14156.6 KXX77929.1 - 1.1 9.2 3.9 5.4 7.0 0.0 3.1 3 0 0 3 3 3 0 Antirepressor AbbA FAD_binding_3 PF01494.19 KXX77931.1 - 3.4e-18 66.0 0.2 3.3e-17 62.7 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX77931.1 - 3.1e-06 27.3 0.4 6.7e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX77931.1 - 4.7e-06 26.0 0.5 0.018 14.3 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXX77931.1 - 0.0001 21.4 0.0 0.00038 19.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KXX77931.1 - 0.00024 20.8 1.2 0.0017 18.0 1.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX77931.1 - 0.0099 16.4 0.2 0.045 14.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX77931.1 - 0.011 14.8 0.4 0.029 13.5 0.5 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KXX77931.1 - 0.012 14.9 0.2 0.15 11.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXX77931.1 - 0.11 11.8 0.2 0.25 10.6 0.2 1.6 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.17 KXX77931.1 - 0.18 11.0 0.2 0.35 10.1 0.2 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KXX77931.1 - 0.31 10.1 0.9 0.46 9.5 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Transp_cyt_pur PF02133.15 KXX77932.1 - 1.3e-28 100.0 29.3 1e-27 97.1 29.3 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RibD_C PF01872.17 KXX77933.1 - 1e-30 107.1 0.0 1.3e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF5308 PF17233.2 KXX77933.1 - 0.027 14.7 0.2 0.034 14.4 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Secretin_N_2 PF07655.13 KXX77933.1 - 0.046 14.3 18.3 0.09 13.3 18.3 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DMAP_binding PF06464.11 KXX77933.1 - 0.13 13.0 3.7 0.21 12.4 3.7 1.2 1 0 0 1 1 1 0 DMAP1-binding Domain Tim54 PF11711.8 KXX77933.1 - 0.24 10.1 0.7 0.31 9.8 0.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 KXX77933.1 - 0.29 10.3 1.7 0.39 9.9 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 KXX77933.1 - 0.37 9.5 4.0 0.5 9.1 4.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KXX77933.1 - 0.43 9.3 2.0 0.51 9.1 2.0 1.1 1 0 0 1 1 1 0 Presenilin NST1 PF13945.6 KXX77933.1 - 0.78 9.8 12.7 1.1 9.4 12.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Menin PF05053.13 KXX77933.1 - 1.1 7.6 7.1 1.2 7.4 7.1 1.1 1 0 0 1 1 1 0 Menin Apc15p PF05841.11 KXX77933.1 - 2.4 9.0 14.7 3.7 8.4 14.7 1.2 1 0 0 1 1 1 0 Apc15p protein Macoilin PF09726.9 KXX77933.1 - 5.3 5.5 7.1 6.3 5.2 7.1 1.0 1 0 0 1 1 1 0 Macoilin family Npa1 PF11707.8 KXX77934.1 - 1.9e-105 353.0 0.1 7.5e-105 351.0 0.0 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KXX77934.1 - 2e-58 197.3 0.1 7.3e-58 195.5 0.0 2.1 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 DUF3926 PF13080.6 KXX77934.1 - 0.1 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Arm PF00514.23 KXX77934.1 - 0.14 12.2 0.7 0.48 10.6 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Histone PF00125.24 KXX77935.1 - 3 8.2 5.3 2 8.8 0.2 2.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 HET PF06985.11 KXX77936.1 - 1.7e-29 103.0 0.1 2.8e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RPA_C PF08784.11 KXX77937.1 - 7.5e-17 61.9 0.4 2.1e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KXX77937.1 - 4.4e-07 29.8 0.1 9.9e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KXX77937.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Acetyltransf_1 PF00583.25 KXX77938.1 - 8e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXX77938.1 - 2.7e-07 30.7 0.0 4.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX77938.1 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX77938.1 - 1.3e-06 28.8 0.0 2.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX77938.1 - 0.00053 19.9 0.0 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXX77938.1 - 0.04 14.1 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NUDIX PF00293.28 KXX77939.1 - 7.7e-26 90.7 0.0 1.2e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MatE PF01554.18 KXX77941.1 - 8e-58 194.6 29.3 5.6e-33 113.9 10.8 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXX77941.1 - 0.00047 20.2 10.7 0.00047 20.2 10.7 4.1 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain GMC_oxred_N PF00732.19 KXX77942.1 - 1.6e-36 126.2 0.2 4.4e-35 121.5 0.2 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX77942.1 - 2.8e-24 86.3 0.0 5.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXX77942.1 - 9.2e-06 25.1 0.7 0.00021 20.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX77942.1 - 0.00014 22.0 0.1 0.00014 22.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX77942.1 - 0.00025 20.4 1.0 0.031 13.6 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX77942.1 - 0.002 17.3 0.2 0.0046 16.1 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXX77942.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KXX77942.1 - 0.03 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXX77942.1 - 0.035 13.3 0.1 0.069 12.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain PEP_mutase PF13714.6 KXX77943.1 - 5.4e-58 196.3 2.3 6.2e-58 196.1 2.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Sporozoite_P67 PF05642.11 KXX77945.1 - 0.49 8.4 11.0 0.61 8.1 11.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Fungal_trans PF04082.18 KXX77947.1 - 9.5e-16 57.6 1.1 2.2e-15 56.4 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX77947.1 - 6.3e-08 32.6 12.8 1.2e-07 31.7 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 KXX77947.1 - 0.57 10.6 4.9 1.8 9.0 4.9 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RdRP PF05183.12 KXX77948.1 - 2.4e-131 439.2 0.0 3.3e-131 438.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ADH_zinc_N_2 PF13602.6 KXX77949.1 - 3.2e-25 89.7 0.0 5.3e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX77949.1 - 8.8e-18 64.5 0.1 1.5e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KXX77949.1 - 0.033 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SKG6 PF08693.10 KXX77950.1 - 6.9e-06 25.4 0.7 3.6e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2613 PF11021.8 KXX77950.1 - 0.036 14.2 0.1 0.096 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) TraL PF07178.11 KXX77950.1 - 0.057 13.9 0.1 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 TraL protein CBM_21 PF03370.13 KXX77951.1 - 1.4e-34 118.7 0.1 2.2e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXX77951.1 - 3.9e-11 43.4 0.3 8e-11 42.4 0.3 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Med22 PF06179.12 KXX77952.1 - 7.8e-11 42.1 0.0 1.8e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.20 KXX77953.1 - 8.6e-12 45.5 0.0 9.9e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase GMC_oxred_N PF00732.19 KXX77954.1 - 1.6e-62 211.5 0.0 2e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX77954.1 - 8.7e-33 113.9 0.0 1.9e-32 112.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX77954.1 - 1.1e-06 28.0 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXX77954.1 - 0.012 15.9 0.1 0.038 14.2 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX77954.1 - 0.013 14.8 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX77954.1 - 0.022 14.3 0.0 0.86 9.1 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Mid2 PF04478.12 KXX77955.1 - 0.0099 15.7 0.5 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KXX77955.1 - 0.011 15.1 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF5305 PF17231.2 KXX77955.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 KXX77955.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family SKI PF01202.22 KXX77955.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 Shikimate kinase APG17 PF04108.12 KXX77956.1 - 6.6e-137 456.8 0.5 7.5e-137 456.6 0.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 HALZ PF02183.18 KXX77956.1 - 0.014 15.6 0.2 0.64 10.3 0.0 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Bap31_Bap29_C PF18035.1 KXX77956.1 - 0.017 15.1 1.6 5.2 7.2 0.2 2.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain LXG PF04740.12 KXX77956.1 - 0.054 13.2 2.0 7.9 6.1 0.2 2.8 1 1 0 2 2 2 0 LXG domain of WXG superfamily OmpH PF03938.14 KXX77956.1 - 0.87 9.9 6.6 4.7 7.6 4.0 2.8 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) RIO1 PF01163.22 KXX77957.1 - 3.7e-66 222.3 1.0 5.7e-66 221.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family CDC45 PF02724.14 KXX77957.1 - 5.8 5.1 9.4 9.6 4.4 9.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3464 PF11947.8 KXX77957.1 - 7.2 6.4 7.0 2.4 7.9 3.7 1.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Ribonuc_L-PSP PF01042.21 KXX77958.1 - 3.4e-23 81.9 0.0 4.2e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 KXX77959.1 - 1.1e-51 175.8 31.9 1.1e-51 175.8 31.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX77959.1 - 1.2e-09 37.5 22.9 7.3e-09 35.0 22.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KXX77959.1 - 9.1e-05 21.9 3.7 9.1e-05 21.9 3.7 2.6 3 1 1 4 4 4 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXX77959.1 - 0.00084 17.7 3.6 0.0009 17.7 2.2 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KXX77959.1 - 0.0031 16.0 1.2 0.0049 15.3 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COesterase PF00135.28 KXX77960.1 - 3e-84 283.7 0.0 4e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX77960.1 - 0.0015 18.4 0.2 0.0098 15.8 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX77960.1 - 0.17 11.3 0.6 0.62 9.5 0.2 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family Vps62 PF06101.11 KXX77964.1 - 3.6e-20 71.8 0.0 1.2e-19 70.0 0.0 1.7 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Toxin_10 PF05431.11 KXX77964.1 - 4.5e-05 23.0 4.2 6.9e-05 22.4 4.2 1.2 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 Fil_haemagg_2 PF13332.6 KXX77964.1 - 0.014 15.5 1.5 0.025 14.7 1.5 1.3 1 0 0 1 1 1 0 Hemagglutinin repeat GAD-like PF08887.11 KXX77964.1 - 0.12 12.1 1.8 0.5 10.2 0.0 2.5 2 1 0 2 2 2 0 GAD-like domain CEL_III_C PF18054.1 KXX77964.1 - 3.3 7.8 7.4 6.2 6.9 6.9 1.7 1 1 1 2 2 2 0 CEL-III C-terminal Fungal_trans PF04082.18 KXX77965.1 - 1e-21 77.2 0.0 1.7e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX77965.1 - 2.5e-07 30.7 13.5 5.2e-07 29.7 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KXX77966.1 - 2e-07 31.1 1.4 6.9e-07 29.3 1.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PAE PF03283.13 KXX77966.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Pectinacetylesterase Ank_2 PF12796.7 KXX77967.1 - 1.6e-18 67.1 0.0 2.6e-10 40.7 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX77967.1 - 1.5e-16 60.5 0.0 5.6e-09 36.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX77967.1 - 1.2e-15 56.0 0.0 0.00054 20.2 0.0 4.9 5 0 0 5 5 4 3 Ankyrin repeat Ank PF00023.30 KXX77967.1 - 4.9e-15 55.2 0.2 0.00033 21.0 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat NACHT PF05729.12 KXX77967.1 - 3.9e-10 39.9 0.3 1.3e-09 38.2 0.3 2.0 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KXX77967.1 - 1e-08 35.3 0.2 0.00091 19.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXX77967.1 - 5.4e-06 26.9 0.0 2e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 KXX77967.1 - 0.00069 19.2 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 KXX77967.1 - 0.0024 18.2 0.0 0.0082 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain PEGA PF08308.11 KXX77967.1 - 0.013 15.4 0.0 2.1 8.3 0.0 2.6 3 0 0 3 3 2 0 PEGA domain Abhydrolase_6 PF12697.7 KXX77967.1 - 0.013 16.1 0.0 0.045 14.3 0.0 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family KAP_NTPase PF07693.14 KXX77967.1 - 0.021 14.0 0.1 1.6 7.9 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain PGAP1 PF07819.13 KXX77967.1 - 0.023 14.4 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Zeta_toxin PF06414.12 KXX77967.1 - 0.055 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KXX77967.1 - 0.06 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hydrolase_4 PF12146.8 KXX77967.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ABC_tran PF00005.27 KXX77967.1 - 0.071 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXX77967.1 - 0.072 13.6 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXX77967.1 - 0.078 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Abhydrolase_1 PF00561.20 KXX77967.1 - 0.084 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold AAA_30 PF13604.6 KXX77967.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXX77967.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Abhydrolase_3 PF07859.13 KXX77968.1 - 1.2e-34 120.1 0.0 9.4e-25 87.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 KXX77968.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Beta-lactamase PF00144.24 KXX77969.1 - 6.3e-40 137.4 0.1 7.8e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Aminotran_3 PF00202.21 KXX77970.1 - 2.6e-105 352.4 0.0 3.3e-105 352.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pyridoxal_deC PF00282.19 KXX77971.1 - 3.8e-79 266.1 0.0 5.1e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXX77971.1 - 6.8e-08 31.9 0.0 2.8e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXX77971.1 - 0.021 14.1 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AIP3 PF03915.13 KXX77972.1 - 7.8e-160 532.4 11.0 1.1e-159 531.9 11.0 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 MIP-T3_C PF17749.1 KXX77972.1 - 0.0051 16.8 5.2 0.078 12.9 1.7 3.0 1 1 1 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Lectin_N PF03954.14 KXX77972.1 - 0.0061 16.3 3.9 0.01 15.6 0.4 3.0 3 1 0 3 3 3 1 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 KXX77972.1 - 0.014 15.5 5.8 1.9 8.5 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Wtap PF17098.5 KXX77972.1 - 0.03 14.2 3.4 0.046 13.6 1.0 2.4 2 0 0 2 2 2 0 WTAP/Mum2p family RasGAP_C PF03836.15 KXX77972.1 - 0.31 11.2 5.8 1.5 9.0 0.4 4.2 5 0 0 5 5 5 0 RasGAP C-terminus NPV_P10 PF05531.12 KXX77972.1 - 0.85 10.1 7.3 0.59 10.6 0.2 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FliL PF03748.14 KXX77972.1 - 0.95 10.1 4.4 0.86 10.2 0.1 3.1 3 1 0 3 3 3 0 Flagellar basal body-associated protein FliL FUSC PF04632.12 KXX77972.1 - 9.6 4.6 6.5 13 4.2 4.4 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family LsmAD PF06741.13 KXX77974.1 - 6.5e-28 97.1 2.6 6.5e-28 97.1 2.6 2.8 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KXX77974.1 - 0.0052 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Sulfatase_C PF14707.6 KXX77974.1 - 0.0057 17.4 1.2 1.9 9.2 0.4 2.7 2 0 0 2 2 2 2 C-terminal region of aryl-sulfatase HMGL-like PF00682.19 KXX77976.1 - 1.5e-41 142.8 0.0 1.7e-40 139.2 0.0 1.9 1 1 0 1 1 1 1 HMGL-like DS PF01916.17 KXX77977.1 - 1.4e-130 434.7 0.0 1.7e-130 434.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 KXX77978.1 - 6.1e-10 39.1 1.9 1.9e-05 24.8 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXX77978.1 - 0.00027 20.8 1.3 0.001 18.9 0.0 2.5 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KXX77978.1 - 0.017 15.4 0.8 8.7 6.7 0.2 3.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Methyltransf_23 PF13489.6 KXX77979.1 - 3.9e-06 26.8 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77979.1 - 0.024 15.3 0.0 0.1 13.3 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain SRP54_N PF02881.19 KXX77979.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain KicB PF03882.14 KXX77979.1 - 0.2 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 MukF winged-helix domain Methyltransf_2 PF00891.18 KXX77980.1 - 7.1e-29 100.6 0.0 3.9e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXX77980.1 - 8.2e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain AAA_33 PF13671.6 KXX77980.1 - 0.029 14.5 1.7 0.049 13.8 0.5 1.9 2 0 0 2 2 2 0 AAA domain Dimerisation PF08100.11 KXX77980.1 - 0.039 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain p450 PF00067.22 KXX77981.1 - 4.2e-42 144.5 0.0 4.8e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXX77982.1 - 3.6e-23 82.0 0.0 6e-23 81.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KXX77982.1 - 0.0053 15.6 0.1 0.0082 15.0 0.1 1.2 1 0 0 1 1 1 1 Amino acid permease MBOAT_2 PF13813.6 KXX77983.1 - 2.6e-19 69.3 4.1 7.1e-19 67.9 4.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 KXX77984.1 - 1.6e-64 218.4 0.0 1.8e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Holin_BhlA PF10960.8 KXX77984.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 BhlA holin family TctB PF07331.11 KXX77984.1 - 0.074 13.3 0.0 0.67 10.2 0.0 2.4 2 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF92 PF01940.16 KXX77984.1 - 0.21 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 Methyltransf_11 PF08241.12 KXX77985.1 - 5.2e-15 55.9 0.1 1.3e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77985.1 - 3.6e-13 50.0 0.1 7.9e-13 48.9 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX77985.1 - 1.6e-11 44.4 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77985.1 - 9.2e-11 42.4 0.0 1.5e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX77985.1 - 2.2e-09 37.3 0.0 3.7e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX77985.1 - 7.4e-09 35.3 0.0 6.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXX77985.1 - 3.9e-05 23.8 0.0 9.9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KXX77985.1 - 0.00028 20.9 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PepSY_2 PF13670.6 KXX77985.1 - 0.006 16.6 3.8 0.0078 16.2 0.0 2.7 3 0 0 3 3 3 1 Peptidase propeptide and YPEB domain PrmA PF06325.13 KXX77985.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXX77985.1 - 0.074 12.6 0.0 0.75 9.3 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase small domain PCMT PF01135.19 KXX77985.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) P-II PF00543.22 KXX77985.1 - 0.17 12.5 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II GST_N_2 PF13409.6 KXX77986.1 - 1.1e-05 25.7 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXX77986.1 - 0.0018 18.6 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXX77986.1 - 0.005 17.2 0.0 0.0077 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Virul_fac_BrkB PF03631.15 KXX77987.1 - 0.0013 18.4 3.6 0.0013 18.4 3.6 1.6 2 0 0 2 2 2 1 Virulence factor BrkB NmrA PF05368.13 KXX77988.1 - 1.9e-25 89.8 1.0 2.4e-25 89.4 1.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX77988.1 - 8.7e-20 71.4 0.5 2.9e-19 69.7 0.1 2.0 3 0 0 3 3 3 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXX77988.1 - 0.00028 21.2 0.1 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXX77988.1 - 0.011 15.2 0.0 4.2 6.8 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF2913 PF11140.8 KXX77988.1 - 0.11 12.2 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) Methyltransf_11 PF08241.12 KXX77989.1 - 1.9e-11 44.4 0.0 3.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77989.1 - 1.1e-10 42.1 0.0 2.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77989.1 - 0.0081 16.9 0.0 0.013 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX77989.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXX77990.1 - 9e-09 35.4 0.0 3.6e-08 33.4 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX77990.1 - 1.9e-07 31.7 0.0 4.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX77990.1 - 1.4e-06 29.0 0.0 2.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX77990.1 - 1.3e-05 25.0 0.0 0.00037 20.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX77990.1 - 0.0001 22.9 0.0 0.00024 21.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KXX77990.1 - 0.0056 16.8 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KXX77990.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family AMP-binding PF00501.28 KXX77992.1 - 7.9e-66 222.4 0.0 1.1e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXX77992.1 - 5.3e-41 140.7 0.0 1.9e-18 66.4 0.0 3.6 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KXX77992.1 - 1e-16 61.0 0.0 8e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXX77992.1 - 0.0062 17.5 0.0 0.025 15.6 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 KXX77993.1 - 9.5e-07 28.8 7.6 2.9e-06 27.3 7.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSC PF09402.10 KXX77993.1 - 0.046 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DinB_2 PF12867.7 KXX77993.1 - 0.047 14.2 0.2 0.77 10.3 0.2 2.7 1 1 0 1 1 1 0 DinB superfamily Pyr_redox_2 PF07992.14 KXX77994.1 - 5.5e-19 68.5 0.0 3.2e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX77994.1 - 5.3e-09 35.7 0.0 2.1e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KXX77994.1 - 0.00013 21.2 0.0 0.00032 19.9 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KXX77994.1 - 0.00096 18.5 0.1 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXX77994.1 - 0.001 19.2 0.1 0.0024 18.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX77994.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXX77994.1 - 0.003 16.9 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXX77994.1 - 0.0033 16.2 0.0 0.0059 15.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KXX77994.1 - 0.0052 16.2 0.1 0.008 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXX77994.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXX77994.1 - 0.04 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXX77994.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXX77994.1 - 0.096 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AIG2_2 PF13772.6 KXX77995.1 - 0.00011 22.5 0.0 0.00021 21.6 0.0 1.5 1 1 0 1 1 1 1 AIG2-like family Aminotran_1_2 PF00155.21 KXX77996.1 - 7e-38 130.7 0.0 8.9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S10 PF00450.22 KXX77997.1 - 1.2e-62 212.7 0.0 4.3e-57 194.4 0.0 2.1 1 1 1 2 2 2 2 Serine carboxypeptidase CobT PF06213.12 KXX77999.1 - 0.075 12.4 1.8 0.1 11.9 1.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 KXX77999.1 - 3.7 6.6 10.1 4.4 6.3 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acetyltransf_10 PF13673.7 KXX78000.1 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX78000.1 - 0.0043 17.4 0.1 0.007 16.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX78000.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 KXX78000.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein FAD_binding_4 PF01565.23 KXX78001.1 - 8.9e-19 67.6 1.1 2e-18 66.5 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX78001.1 - 5.8e-11 42.3 0.2 1.3e-10 41.2 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.7 KXX78002.1 - 4.5e-06 26.4 0.1 2e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KXX78002.1 - 2.5e-05 24.0 0.6 6.2e-05 22.8 0.6 1.7 1 0 0 1 1 1 1 F-box domain IQ PF00612.27 KXX78002.1 - 0.18 11.7 0.8 0.4 10.6 0.8 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Rhabdo_M2 PF04785.12 KXX78002.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Pyr_redox_2 PF07992.14 KXX78003.1 - 4e-20 72.2 0.5 8.8e-19 67.8 0.5 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX78003.1 - 2.3e-07 30.3 0.0 5.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX78003.1 - 4.4e-06 26.5 3.5 9e-05 22.2 1.0 2.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX78003.1 - 6.8e-06 25.0 0.0 0.0001 21.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXX78003.1 - 9e-06 25.0 0.5 0.0012 18.0 0.6 2.2 1 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXX78003.1 - 1.6e-05 24.3 0.1 0.00011 21.5 0.0 2.2 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX78003.1 - 4.6e-05 23.6 0.4 0.00013 22.2 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX78003.1 - 6.1e-05 22.4 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXX78003.1 - 0.00011 22.3 0.7 0.48 10.4 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXX78003.1 - 0.00081 18.8 0.7 0.0013 18.1 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX78003.1 - 0.00082 18.7 0.1 0.0021 17.4 0.1 1.7 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXX78003.1 - 0.0027 16.8 0.4 0.024 13.7 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXX78003.1 - 0.0028 18.1 0.2 0.17 12.3 0.0 2.5 3 0 0 3 3 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KXX78003.1 - 0.0099 15.2 0.0 0.0099 15.2 0.0 2.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KXX78003.1 - 0.022 13.6 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Glyco_transf_4 PF13439.6 KXX78003.1 - 0.045 13.8 0.3 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 TauD PF02668.16 KXX78006.1 - 8e-37 127.5 0.0 1e-36 127.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXX78006.1 - 0.0012 18.0 0.1 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 CsiD Ecl1 PF12855.7 KXX78007.1 - 9.1e-36 124.6 19.4 9.1e-36 124.6 19.4 2.0 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 KXX78007.1 - 0.0068 15.9 1.8 0.014 14.8 1.8 1.5 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 PLATZ PF04640.14 KXX78007.1 - 0.14 12.8 0.2 0.22 12.1 0.2 1.3 1 0 0 1 1 1 0 PLATZ transcription factor XhlA PF10779.9 KXX78008.1 - 9.7e-06 25.7 1.1 0.017 15.3 0.2 2.4 1 1 1 2 2 2 2 Haemolysin XhlA CLZ PF16526.5 KXX78008.1 - 1.5e-05 25.3 1.2 0.008 16.5 0.2 2.5 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSBP1 PF06825.12 KXX78008.1 - 2.9e-05 23.8 1.2 0.00013 21.8 1.2 2.2 1 1 0 1 1 1 1 Heat shock factor binding protein 1 EzrA PF06160.12 KXX78008.1 - 0.00038 18.8 0.1 0.00049 18.4 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA UPF0184 PF03670.13 KXX78008.1 - 0.0016 18.8 0.4 0.015 15.6 0.4 2.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) DUF4164 PF13747.6 KXX78008.1 - 0.0019 18.4 1.4 0.91 9.8 0.6 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4164) MscS_porin PF12795.7 KXX78008.1 - 0.0056 16.3 0.1 0.007 15.9 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Vac_Fusion PF02346.16 KXX78008.1 - 0.0058 16.2 1.5 0.062 12.9 1.5 2.5 2 1 0 2 2 1 1 Chordopoxvirus multifunctional envelope protein A27 ABC_tran_CTD PF16326.5 KXX78008.1 - 0.0062 16.8 0.1 1.2 9.4 0.1 2.4 1 1 0 2 2 2 1 ABC transporter C-terminal domain NPV_P10 PF05531.12 KXX78008.1 - 0.0077 16.7 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXX78008.1 - 0.0085 16.5 0.3 0.097 13.1 0.0 2.1 1 1 1 2 2 2 2 Flagella accessory protein C (FlaC) Osmo_CC PF08946.10 KXX78008.1 - 0.021 15.0 3.5 0.042 14.1 0.3 2.6 2 1 1 3 3 2 0 Osmosensory transporter coiled coil Prefoldin_2 PF01920.20 KXX78008.1 - 0.022 14.7 0.1 2.7 8.0 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit YvrJ PF12841.7 KXX78008.1 - 0.023 14.2 3.9 4.8 6.8 0.1 3.4 3 1 0 3 3 3 0 YvrJ protein family Nsp1_C PF05064.13 KXX78008.1 - 0.023 14.5 0.1 0.098 12.5 0.1 2.0 1 1 0 1 1 1 0 Nsp1-like C-terminal region Baculo_PEP_C PF04513.12 KXX78008.1 - 0.024 14.7 0.1 0.049 13.7 0.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.6 KXX78008.1 - 0.026 14.6 0.2 2 8.5 0.1 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term COG6 PF06419.11 KXX78008.1 - 0.032 12.5 0.1 0.043 12.0 0.1 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Tropomyosin PF00261.20 KXX78008.1 - 0.035 13.5 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin TRPM_tetra PF16519.5 KXX78008.1 - 0.035 14.2 0.4 5.2 7.3 0.1 2.5 1 1 1 2 2 2 0 Tetramerisation domain of TRPM Cluap1 PF10234.9 KXX78008.1 - 0.041 13.3 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 COG5 PF10392.9 KXX78008.1 - 0.041 14.1 0.1 11 6.2 0.0 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Allexi_40kDa PF05549.11 KXX78008.1 - 0.046 13.2 0.2 0.065 12.7 0.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4455 PF14643.6 KXX78008.1 - 0.051 12.2 0.2 0.057 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF2730 PF10805.8 KXX78008.1 - 0.054 13.6 0.2 0.21 11.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) LegC3_N PF18654.1 KXX78008.1 - 0.054 12.7 0.2 0.071 12.3 0.2 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Snapin_Pallidin PF14712.6 KXX78008.1 - 0.064 13.7 0.0 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin ADIP PF11559.8 KXX78008.1 - 0.065 13.3 0.5 0.23 11.5 0.4 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Spc19 PF08287.11 KXX78008.1 - 0.066 13.1 0.4 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Spc19 Laminin_II PF06009.12 KXX78008.1 - 0.075 13.1 0.1 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 Laminin Domain II Nup54 PF13874.6 KXX78008.1 - 0.088 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RmuC PF02646.16 KXX78008.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 RmuC family DUF16 PF01519.16 KXX78008.1 - 0.13 12.8 0.7 13 6.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spc24 PF08286.11 KXX78008.1 - 0.13 12.5 0.6 1.6 9.0 0.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF812 PF05667.11 KXX78008.1 - 0.16 10.8 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 KXX78008.1 - 0.16 11.5 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit vATP-synt_E PF01991.18 KXX78008.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit MtrG PF04210.13 KXX78008.1 - 0.2 11.5 0.1 4.9 7.1 0.0 2.3 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G CCDC53 PF10152.9 KXX78008.1 - 0.21 12.0 0.4 4.7 7.6 0.4 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex TMPIT PF07851.13 KXX78008.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.3 1 1 0 1 1 1 0 TMPIT-like protein Sugarporin_N PF11471.8 KXX78008.1 - 0.25 11.3 1.6 4.8 7.2 0.4 2.4 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension HalX PF08663.10 KXX78008.1 - 0.38 11.1 5.0 7.6 6.9 4.4 2.4 1 1 1 2 2 2 0 HalX domain SlyX PF04102.12 KXX78008.1 - 0.41 11.3 2.4 26 5.5 0.3 2.4 1 1 1 2 2 2 0 SlyX Trimer_CC PF08954.11 KXX78008.1 - 1.4 8.5 7.2 5.7 6.6 0.1 3.1 2 1 0 2 2 2 0 Trimerisation motif DUF2428 PF10350.9 KXX78010.1 - 1.1e-58 198.7 0.1 2.6e-58 197.5 0.1 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KXX78010.1 - 6.6e-06 25.9 11.3 8.9 6.9 0.0 7.4 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 KXX78010.1 - 0.00017 21.9 0.6 0.23 11.8 0.0 4.2 5 0 0 5 5 5 2 HEAT repeats Polyoma_agno PF01736.16 KXX78010.1 - 0.11 12.2 0.8 22 4.9 0.0 3.6 3 0 0 3 3 3 0 Polyomavirus agnoprotein CoaE PF01121.20 KXX78011.1 - 1.2e-42 145.6 0.0 5.4e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 KXX78011.1 - 0.0095 16.1 0.0 0.11 12.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXX78011.1 - 0.018 15.6 0.2 0.3 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CcmH PF03918.14 KXX78011.1 - 0.028 13.7 0.9 0.049 12.9 0.9 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein FixP_N PF14715.6 KXX78011.1 - 0.14 11.9 3.1 0.26 11.1 3.1 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Lectin_leg-like PF03388.13 KXX78012.1 - 9.5e-26 90.6 0.0 1.7e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.12 KXX78012.1 - 0.00038 20.5 0.3 0.013 15.5 0.1 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus FSIP1 PF15554.6 KXX78012.1 - 0.0007 18.8 5.3 0.00095 18.4 5.3 1.1 1 0 0 1 1 1 1 FSIP1 family DUF4175 PF13779.6 KXX78012.1 - 0.00081 17.4 13.9 0.001 17.1 13.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) TFIIA PF03153.13 KXX78012.1 - 0.07 13.1 12.1 0.095 12.7 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC-167 PF15188.6 KXX78012.1 - 0.091 13.1 1.2 0.95 9.8 0.8 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Spt20 PF12090.8 KXX78012.1 - 0.099 12.2 16.0 0.15 11.6 16.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 KXX78012.1 - 0.16 10.9 11.9 0.24 10.3 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CNDH2_M PF16869.5 KXX78012.1 - 0.58 10.9 10.3 0.82 10.4 9.6 1.5 1 1 0 1 1 1 0 PF16858 SpoIIIAH PF12685.7 KXX78012.1 - 1.3 8.8 9.8 0.98 9.2 7.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF4407 PF14362.6 KXX78012.1 - 8 5.7 9.6 13 5.1 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M24 PF00557.24 KXX78013.1 - 2.2e-61 207.2 0.1 5.1e-61 206.0 0.1 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXX78013.1 - 1.4e-19 70.0 0.0 2.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain WAC_Acf1_DNA_bd PF10537.9 KXX78014.1 - 1e-38 131.9 1.6 1.8e-38 131.1 0.0 2.4 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KXX78014.1 - 8.4e-17 61.5 0.0 8.4e-17 61.5 0.0 4.0 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KXX78014.1 - 4.2e-16 59.0 0.1 7.8e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KXX78014.1 - 6.3e-10 38.3 0.1 4.2e-08 32.5 0.0 2.6 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF87 PF01935.17 KXX78014.1 - 0.14 12.2 1.5 0.38 10.8 1.5 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain CCDC-167 PF15188.6 KXX78014.1 - 0.33 11.3 0.0 0.33 11.3 0.0 3.4 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 Alg6_Alg8 PF03155.15 KXX78015.1 - 1.3e-178 595.0 28.8 1.5e-178 594.7 28.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Fungal_trans_2 PF11951.8 KXX78016.1 - 0.05 12.4 0.4 0.071 11.9 0.4 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX78016.1 - 0.097 12.8 8.2 0.21 11.7 8.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HisKA_4TM PF16926.5 KXX78016.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase Thioredoxin_6 PF13848.6 KXX78017.1 - 7.5e-19 68.3 0.0 1.1e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain E1_FCCH PF16190.5 KXX78017.1 - 0.048 13.9 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain FeoB_Cyto PF17910.1 KXX78017.1 - 0.076 13.6 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 FeoB cytosolic helical domain UvrD_C_2 PF13538.6 KXX78017.1 - 0.14 12.0 0.0 9.6 6.1 0.0 2.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Kelch_5 PF13854.6 KXX78018.1 - 1.7e-13 50.2 12.0 6.9e-12 45.1 0.2 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.6 KXX78018.1 - 0.0044 17.2 13.2 2 8.8 0.1 5.8 5 1 1 6 6 6 2 Kelch motif Kelch_4 PF13418.6 KXX78018.1 - 0.0051 16.8 12.8 1.2 9.2 0.1 5.9 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KXX78018.1 - 0.06 12.9 0.8 24 4.6 0.0 4.1 4 0 0 4 4 4 0 Kelch motif Trp_oprn_chp PF09534.10 KXX78018.1 - 0.073 12.9 0.1 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Kelch_2 PF07646.15 KXX78018.1 - 2.3 8.3 9.4 36 4.6 0.0 5.0 6 0 0 6 6 6 0 Kelch motif MFS_1 PF07690.16 KXX78019.1 - 1.5e-35 122.7 50.7 8e-35 120.4 45.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RPN7 PF10602.9 KXX78020.1 - 1.9e-44 151.4 0.0 3.3e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXX78020.1 - 3.4e-13 50.0 0.1 1.1e-12 48.3 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_20 PF14561.6 KXX78020.1 - 3.5 8.0 6.0 11 6.5 0.9 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KXX78021.1 - 4e-30 104.7 0.0 5.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX78021.1 - 1.8e-10 40.8 14.6 3.3e-10 39.9 14.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Band_7 PF01145.25 KXX78021.1 - 0.22 11.5 1.0 0.5 10.4 1.0 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family Fer2 PF00111.27 KXX78021.1 - 0.59 10.1 3.6 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain GST_N PF02798.20 KXX78022.1 - 0.00016 21.9 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXX78022.1 - 0.00037 20.9 0.0 0.00066 20.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX78022.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NDUF_B4 PF07225.12 KXX78023.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Tim17 PF02466.19 KXX78024.1 - 3.1e-27 95.1 1.9 4.5e-27 94.6 1.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Endonuclease_5 PF04493.14 KXX78024.1 - 0.03 14.0 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Endonuclease V STAT1_TAZ2bind PF12162.8 KXX78025.1 - 0.18 11.4 0.3 0.18 11.4 0.3 1.7 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain Abhydrolase_6 PF12697.7 KXX78026.1 - 0.0045 17.6 4.6 0.0077 16.9 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family LCAT PF02450.15 KXX78026.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 KXX78026.1 - 0.022 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXX78026.1 - 0.052 12.8 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Gtr1_RagA PF04670.12 KXX78027.1 - 3e-70 236.2 0.1 3.8e-70 235.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KXX78027.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 KXX78027.1 - 0.031 14.6 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 KXX78027.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXX78027.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase MIF PF01187.18 KXX78028.1 - 2.1e-07 31.3 0.0 2.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) SAP18 PF06487.12 KXX78029.1 - 6e-40 136.7 0.0 7.3e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 KXX78030.1 - 3.4e-52 176.3 0.0 3.4e-52 176.3 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KXX78030.1 - 2.2e-11 43.1 0.6 2.2e-11 43.1 0.6 3.2 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like DUF966 PF06136.13 KXX78030.1 - 0.076 12.7 5.2 0.095 12.4 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 KXX78030.1 - 9.8 4.8 10.0 13 4.4 10.0 1.2 1 0 0 1 1 1 0 Presenilin Cation_ATPase_C PF00689.21 KXX78031.1 - 1.6e-43 148.5 5.2 1.6e-43 148.5 5.2 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXX78031.1 - 4.7e-35 120.8 1.0 4.7e-35 120.8 1.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXX78031.1 - 1.9e-22 79.2 0.0 3.5e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX78031.1 - 7.6e-22 78.6 0.1 2.4e-21 77.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXX78031.1 - 4.6e-06 26.6 0.6 9.5e-06 25.5 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX78031.1 - 1e-05 25.1 3.6 2.9e-05 23.7 0.0 3.1 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus LptF_LptG PF03739.14 KXX78031.1 - 0.0033 16.3 3.5 0.0073 15.2 3.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF2976 PF11190.8 KXX78031.1 - 0.014 15.2 8.2 1.1 9.0 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Pkinase PF00069.25 KXX78032.1 - 3.3e-15 56.2 0.0 1.1e-14 54.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78032.1 - 1.4e-07 31.1 0.0 4.3e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 KXX78032.1 - 0.0025 17.5 0.5 0.12 12.1 0.2 2.4 1 1 1 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 SIR2 PF02146.17 KXX78033.1 - 1.6e-59 200.8 0.0 2.1e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KXX78033.1 - 0.0035 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KXX78033.1 - 0.01 15.5 0.1 0.94 9.2 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Med16 PF11635.8 KXX78033.1 - 0.082 10.8 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 ESSS PF10183.9 KXX78034.1 - 2.6e-15 56.5 0.0 3.3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Piwi PF02171.17 KXX78035.1 - 4.9e-73 246.0 0.0 7.1e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 KXX78035.1 - 2.6e-11 43.7 0.0 9.3e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KXX78035.1 - 1e-10 41.1 0.0 2.2e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KXX78035.1 - 4.9e-07 30.4 0.0 2.3e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 N-terminal domain of argonaute Glucosamine_iso PF01182.20 KXX78036.1 - 1.2e-23 84.2 0.0 1.8e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RGCC PF15151.6 KXX78037.1 - 0.044 14.0 0.3 0.075 13.3 0.3 1.6 1 1 0 1 1 1 0 Response gene to complement 32 protein family Plasmod_MYXSPDY PF07981.11 KXX78037.1 - 0.045 13.7 25.6 0.15 12.1 2.5 5.3 1 1 4 5 5 5 0 Plasmodium repeat_MYXSPDY Aminotran_4 PF01063.19 KXX78038.1 - 1.3e-36 126.5 0.0 1.9e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV RAP1 PF07218.11 KXX78039.1 - 2.2 6.5 3.6 2.6 6.2 3.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PEMT PF04191.13 KXX78040.1 - 1.7e-32 112.0 6.1 3.3e-32 111.0 4.4 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase NDT80_PhoG PF05224.12 KXX78041.1 - 4e-34 118.5 0.0 8.6e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.16 KXX78042.1 - 1.9e-55 187.9 0.0 2.5e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXX78042.1 - 4e-44 150.9 0.0 6e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Pyridox_ox_2 PF12900.7 KXX78043.1 - 2.8e-36 124.6 0.0 4.2e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Enkurin PF13864.6 KXX78043.1 - 0.15 12.6 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 Calmodulin-binding Spermine_synth PF01564.17 KXX78044.1 - 3.7e-08 33.0 0.0 6.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KXX78044.1 - 0.001 18.9 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Mannosidase_ig PF17786.1 KXX78045.1 - 0.25 12.0 1.1 34 5.1 0.0 2.4 2 0 0 2 2 2 0 Mannosidase Ig/CBM-like domain Na_H_Exchanger PF00999.21 KXX78046.1 - 7.9e-58 196.1 38.9 1.1e-57 195.5 38.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pyr_redox_2 PF07992.14 KXX78047.1 - 1.3e-49 169.0 0.3 2.2e-49 168.3 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX78047.1 - 2.2e-19 69.8 1.8 2.1e-17 63.4 0.1 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KXX78047.1 - 9e-15 54.8 5.6 1.6e-11 44.3 6.8 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 KXX78047.1 - 3.5e-14 52.6 0.6 8.9e-14 51.3 0.0 1.9 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 KXX78047.1 - 3.8e-12 46.1 0.0 1.9e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KXX78047.1 - 9.6e-12 44.7 0.1 8.8e-11 41.6 0.0 2.5 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KXX78047.1 - 1.3e-08 34.6 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KXX78047.1 - 6.9e-06 25.9 0.3 0.032 14.2 0.1 3.5 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KXX78047.1 - 0.00037 20.5 0.2 2.5 8.1 0.1 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KXX78047.1 - 0.1 13.1 0.2 3 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding K_oxygenase PF13434.6 KXX78047.1 - 0.11 11.6 0.0 0.28 10.3 0.0 1.6 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 KXX78047.1 - 0.19 12.0 0.8 17 5.7 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain SGP PF17228.2 KXX78047.1 - 4.9 8.1 15.7 14 6.6 15.5 1.8 1 1 0 1 1 1 0 Sulphur globule protein Glyco_hydro_3 PF00933.21 KXX78049.1 - 2.8e-61 207.6 0.0 3.8e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXX78049.1 - 0.00038 20.5 0.0 0.00083 19.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 KXX78049.1 - 0.0013 18.9 0.0 0.0047 17.1 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX78049.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fe_hyd_SSU PF02256.17 KXX78049.1 - 0.07 13.2 0.4 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Iron hydrogenase small subunit Amidohydro_1 PF01979.20 KXX78050.1 - 2.6e-11 43.5 0.0 2.4e-10 40.3 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXX78050.1 - 4.8e-10 39.5 0.2 1.2e-06 28.3 0.1 3.2 4 0 0 4 4 4 2 Amidohydrolase family Ceramidase_alk PF04734.13 KXX78051.1 - 5.8e-225 747.7 0.0 6.8e-225 747.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KXX78051.1 - 5.7e-60 202.0 0.0 9.8e-60 201.2 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Rcd1 PF04078.13 KXX78052.1 - 2.6e-126 420.2 3.7 3e-126 420.0 3.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like baeRF_family10 PF18854.1 KXX78052.1 - 0.13 12.5 3.3 4.8 7.4 0.6 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 zf-MYND PF01753.18 KXX78053.1 - 2.2e-11 43.6 13.3 5.6e-11 42.3 13.3 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXX78053.1 - 0.035 14.4 8.6 0.035 14.4 8.6 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KXX78053.1 - 0.33 11.1 7.5 0.74 10.0 7.5 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.7 KXX78053.1 - 2 9.5 6.8 4.8 8.3 6.9 1.5 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins F-box-like PF12937.7 KXX78054.1 - 9.2e-08 31.9 0.3 2.5e-07 30.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KXX78054.1 - 0.00014 21.8 0.1 0.00078 19.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.33 KXX78054.1 - 0.0029 17.4 3.5 0.0041 17.0 0.4 2.8 3 1 0 3 3 3 1 F-box domain HALZ PF02183.18 KXX78054.1 - 0.043 14.0 0.2 0.086 13.1 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Sugar_tr PF00083.24 KXX78055.1 - 1.9e-106 356.6 17.9 2.4e-106 356.3 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX78055.1 - 4.4e-20 71.9 46.6 2.8e-17 62.7 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KXX78056.1 - 1.3e-34 119.4 0.2 2.2e-34 118.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX78056.1 - 7.8e-28 97.6 0.1 1.2e-27 97.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX78056.1 - 2.3e-06 27.6 5.1 3.5e-05 23.8 5.1 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX78056.1 - 0.00048 19.7 0.1 0.00069 19.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXX78056.1 - 0.032 13.6 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HDPD PF02924.14 KXX78056.1 - 0.075 13.1 0.2 0.075 13.1 0.2 1.6 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D DUF3455 PF11937.8 KXX78056.1 - 0.19 12.1 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) DUF3509 PF12021.8 KXX78056.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Pkinase PF00069.25 KXX78057.1 - 4.9e-09 35.9 0.0 9.6e-05 21.9 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Imm1 PF14430.6 KXX78057.1 - 0.024 15.3 0.0 0.07 13.8 0.0 1.7 1 0 0 1 1 1 0 Immunity protein Imm1 Sof1 PF04158.14 KXX78059.1 - 7.5e-32 109.5 15.6 1.3e-31 108.6 15.6 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KXX78059.1 - 5.9e-25 87.1 12.3 1.5e-06 28.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX78059.1 - 9.6e-09 35.4 0.4 0.11 12.8 0.0 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KXX78059.1 - 2.4e-05 24.3 0.5 0.17 11.9 0.0 4.7 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 KXX78059.1 - 0.017 15.6 1.4 10 6.8 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain Cytochrom_D1 PF02239.16 KXX78059.1 - 0.021 13.4 0.3 0.088 11.3 0.1 2.1 2 1 1 3 3 3 0 Cytochrome D1 heme domain RPN6_N PF18055.1 KXX78060.1 - 7.1e-48 161.8 3.7 7.7e-48 161.7 0.5 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KXX78060.1 - 5.9e-21 74.9 0.9 1.9e-20 73.3 0.2 2.3 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 KXX78060.1 - 5.6e-11 42.0 0.8 1.3e-10 40.8 0.8 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KXX78060.1 - 0.00014 21.6 6.1 1.2 9.3 1.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX78060.1 - 0.00029 20.3 2.4 0.00029 20.3 2.4 2.4 2 2 0 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 KXX78060.1 - 0.00039 20.1 0.3 0.00039 20.1 0.3 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_2 PF07719.17 KXX78060.1 - 0.0018 18.2 6.0 9.4 6.6 0.0 5.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX78060.1 - 0.002 18.4 22.2 0.27 11.6 2.3 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX78060.1 - 0.036 13.9 7.3 8.6 6.4 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KXX78060.1 - 0.048 13.7 0.1 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 KXX78060.1 - 0.063 13.4 0.1 0.32 11.2 0.0 2.2 3 0 0 3 3 2 0 DprA winged helix domain DUF87 PF01935.17 KXX78060.1 - 0.22 11.6 1.5 0.93 9.5 0.2 2.2 2 1 0 2 2 2 0 Helicase HerA, central domain TPR_10 PF13374.6 KXX78060.1 - 0.27 11.2 8.4 65 3.6 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX78060.1 - 0.29 12.1 13.7 40 5.4 0.1 6.5 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXX78060.1 - 0.58 10.9 0.1 0.58 10.9 0.1 3.8 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX78060.1 - 2 8.8 13.4 21 5.7 0.0 6.0 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF4398 PF14346.6 KXX78060.1 - 4.2 8.1 15.4 0.071 13.7 1.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) AT_hook PF02178.19 KXX78061.1 - 0.012 15.4 19.0 0.63 10.1 4.5 3.5 2 0 0 2 2 2 0 AT hook motif WD40 PF00400.32 KXX78063.1 - 3.9e-12 46.5 10.2 0.0013 19.5 0.0 6.9 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX78063.1 - 1.6e-11 44.3 0.1 8.5e-05 22.8 0.0 4.7 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXX78063.1 - 0.042 13.7 0.0 2.5 8.0 0.0 3.0 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 KXX78064.1 - 9.2e-36 123.5 49.2 9.2e-36 123.5 49.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX78064.1 - 9.4e-11 41.2 13.2 3e-10 39.6 13.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1072 PF06380.11 KXX78064.1 - 0.16 11.9 0.3 0.51 10.2 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) FAM199X PF15814.5 KXX78064.1 - 0.55 9.2 3.3 0.92 8.5 3.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X Mob1_phocein PF03637.17 KXX78065.1 - 3.3e-70 235.5 0.0 4.3e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_63 PF03200.16 KXX78066.1 - 1.4e-08 33.9 5.9 5.8e-06 25.3 0.1 3.6 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain OSCP PF00213.18 KXX78067.1 - 2.9e-47 161.0 0.7 3.4e-47 160.8 0.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.17 KXX78067.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 Toxin_35 PF10530.9 KXX78068.1 - 0.0006 19.7 6.0 0.00073 19.5 6.0 1.2 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Conotoxin PF02950.17 KXX78068.1 - 0.001 20.1 0.8 0.0011 19.9 0.8 1.3 1 0 0 1 1 1 1 Conotoxin Omega-toxin PF06357.11 KXX78068.1 - 0.049 13.4 5.2 0.069 13.0 5.2 1.3 1 0 0 1 1 1 0 Omega-atracotoxin PP2C PF00481.21 KXX78069.1 - 6.2e-44 150.6 0.0 9.3e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXX78069.1 - 0.0017 18.0 0.3 0.0061 16.2 0.3 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXX78069.1 - 0.011 15.7 0.2 0.91 9.4 0.0 2.6 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) MFS_1 PF07690.16 KXX78070.1 - 1.5e-16 60.3 19.9 5.3e-16 58.5 14.1 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily Osw5 PF17062.5 KXX78070.1 - 2.6 8.2 7.6 4.9 7.3 0.0 3.3 3 0 0 3 3 3 0 Outer spore wall 5 Flexi_CP_N PF08358.10 KXX78071.1 - 0.023 14.7 0.1 0.063 13.3 0.1 1.7 1 0 0 1 1 1 0 Carlavirus coat LSM PF01423.22 KXX78072.1 - 4.9e-15 55.0 0.0 9.9e-15 54.0 0.0 1.5 2 0 0 2 2 2 1 LSM domain Sds3 PF08598.11 KXX78073.1 - 2.8e-22 79.8 3.3 4.2e-22 79.2 3.3 1.3 1 0 0 1 1 1 1 Sds3-like DUF743 PF05332.11 KXX78073.1 - 9.8 6.3 9.3 0.095 12.8 0.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF743) DUF1751 PF08551.10 KXX78074.1 - 8.8e-29 100.0 2.7 8.8e-29 100.0 2.7 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXX78074.1 - 0.16 12.0 9.8 0.37 10.8 9.8 1.5 1 0 0 1 1 1 0 Rhomboid family WW PF00397.26 KXX78075.1 - 3.6e-11 42.9 0.1 3.6e-11 42.9 0.1 2.6 3 0 0 3 3 3 1 WW domain p450 PF00067.22 KXX78075.1 - 0.0017 17.2 0.3 0.0026 16.6 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1754 PF08555.10 KXX78076.1 - 7.8e-15 55.5 14.0 1.5e-14 54.5 14.0 1.5 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SVIP PF15811.5 KXX78076.1 - 0.51 10.8 9.3 1.5 9.4 6.4 2.2 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Leu_zip PF15294.6 KXX78076.1 - 0.62 9.5 7.8 0.13 11.7 4.1 1.6 2 0 0 2 2 2 0 Leucine zipper SpoIIIAH PF12685.7 KXX78076.1 - 1.3 8.8 5.3 1.5 8.6 5.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein PRKCSH-like PF12999.7 KXX78076.1 - 1.7 8.4 4.0 0.69 9.7 1.5 1.5 2 0 0 2 2 2 0 Glucosidase II beta subunit-like RR_TM4-6 PF06459.12 KXX78076.1 - 4.3 7.1 10.1 5.2 6.8 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 cobW PF02492.19 KXX78078.1 - 1.9e-39 135.1 0.0 2.8e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KXX78078.1 - 0.0003 20.7 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF463 PF04317.12 KXX78078.1 - 0.047 12.6 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Viral_helicase1 PF01443.18 KXX78078.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KXX78078.1 - 0.049 13.5 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KXX78078.1 - 0.087 13.1 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXX78078.1 - 0.092 12.5 0.1 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain CobW_C PF07683.14 KXX78078.1 - 0.11 12.4 0.0 0.82 9.6 0.0 2.4 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.6 KXX78078.1 - 0.14 12.7 0.0 1.5 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AA_permease PF00324.21 KXX78079.1 - 6.8e-61 206.3 29.2 8.6e-61 206.0 29.2 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KXX78079.1 - 1.7e-25 89.9 0.7 5.1e-09 35.7 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KXX78079.1 - 9.9e-16 57.6 34.8 1.5e-15 57.0 34.8 1.2 1 0 0 1 1 1 1 Amino acid permease zf-C3HC4_4 PF15227.6 KXX78079.1 - 0.18 12.0 3.3 0.49 10.6 3.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PALP PF00291.25 KXX78080.1 - 4.1e-64 216.8 0.5 5e-64 216.5 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N_2 PF13602.6 KXX78080.1 - 0.047 14.7 0.1 5.7 8.0 0.0 2.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase SPO11_like PF03533.14 KXX78080.1 - 0.097 12.8 0.2 0.42 10.7 0.1 2.1 2 0 0 2 2 2 0 SPO11 homologue DNA_pol_E_B PF04042.16 KXX78081.1 - 6.1e-50 169.5 0.0 8.1e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KXX78081.1 - 6.9e-39 132.9 0.0 1.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain tRNA-synt_1g PF09334.11 KXX78082.1 - 1.9e-92 310.0 0.9 5.1e-91 305.3 0.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXX78082.1 - 1.5e-22 79.7 7.2 2.7e-09 35.8 0.6 4.0 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KXX78082.1 - 1.6e-09 37.6 0.0 0.00073 19.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KXX78082.1 - 0.0093 15.9 0.0 0.073 13.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Acetyltransf_3 PF13302.7 KXX78083.1 - 2.1e-22 80.3 0.0 3e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX78083.1 - 2.5e-06 27.4 0.2 0.0048 16.8 0.2 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KXX78083.1 - 3.3e-06 26.9 1.3 0.25 11.0 0.0 3.2 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX78083.1 - 0.00068 20.0 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX78083.1 - 0.0062 16.8 0.6 0.051 13.8 0.5 2.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXX78083.1 - 0.032 14.4 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXX78083.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Dak1 PF02733.17 KXX78084.1 - 3.9e-102 341.3 7.3 5.5e-102 340.8 7.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXX78084.1 - 2.9e-47 160.8 0.7 5.9e-47 159.8 0.7 1.5 1 0 0 1 1 1 1 DAK2 domain Asparaginase PF00710.20 KXX78085.1 - 9.1e-58 195.0 0.0 1.2e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXX78085.1 - 2.4e-16 60.0 0.0 3.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain NPV_P10 PF05531.12 KXX78086.1 - 0.13 12.8 1.1 6.7 7.3 1.1 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IF4E PF01652.18 KXX78087.1 - 5.1e-38 130.4 0.3 6.8e-38 130.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HAGH_C PF16123.5 KXX78090.1 - 1.4e-18 67.1 0.0 2.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KXX78090.1 - 4e-18 66.1 4.0 3.3e-16 59.9 4.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXX78090.1 - 0.0014 18.2 0.7 0.0088 15.6 0.7 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1236 PF06823.12 KXX78090.1 - 0.012 15.5 0.0 0.76 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Las1 PF04031.13 KXX78091.1 - 3.9e-62 208.9 0.0 5.3e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 Las1-like Enolase_C PF00113.22 KXX78092.1 - 2e-152 506.6 0.2 2.5e-152 506.3 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KXX78092.1 - 7.1e-58 194.5 0.2 1.9e-57 193.1 0.1 1.8 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KXX78092.1 - 3.6e-05 23.5 0.0 8.2e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KXX78092.1 - 0.013 14.7 0.1 0.52 9.4 0.1 2.8 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus Peptidase_M1 PF01433.20 KXX78093.1 - 3.9e-86 288.1 0.8 5.9e-86 287.5 0.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KXX78093.1 - 9.6e-86 288.2 0.0 4.2e-85 286.0 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KXX78093.1 - 1.5e-50 172.0 1.0 2.7e-50 171.2 0.3 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF5011 PF16403.5 KXX78093.1 - 0.097 12.8 0.4 0.36 11.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) DUF4110 PF13422.6 KXX78094.1 - 1.2e-32 111.8 0.3 1.2e-32 111.8 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KXX78094.1 - 7.5e-26 89.9 15.1 4.3e-07 29.8 0.0 6.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KXX78094.1 - 1.3e-22 79.5 9.5 3.3e-07 30.4 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXX78094.1 - 2.6e-22 78.4 0.6 3.3e-08 33.3 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KXX78094.1 - 3.1e-19 68.5 0.4 0.0002 21.5 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXX78094.1 - 2.6e-16 58.9 1.7 3.5e-05 23.3 0.0 5.5 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KXX78094.1 - 4.4e-15 55.0 2.2 0.0011 18.8 0.0 6.1 6 1 0 6 6 6 3 Kelch motif WLM PF08325.10 KXX78095.1 - 2e-29 103.0 0.2 4.3e-29 102.0 0.1 1.6 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KXX78095.1 - 5.6e-08 33.1 1.5 1.4e-07 31.8 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 DUF5364 PF17322.2 KXX78095.1 - 0.25 11.7 3.8 0.38 11.0 3.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5364) zf-RanBP PF00641.18 KXX78095.1 - 7.5 6.0 10.0 0.58 9.5 4.7 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Sacchrp_dh_C PF16653.5 KXX78096.1 - 3.6e-91 306.0 0.0 8.5e-91 304.7 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KXX78096.1 - 3e-23 82.5 0.2 4.7e-23 81.9 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXX78096.1 - 4.9e-05 23.4 0.0 9.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KXX78096.1 - 0.0032 17.4 0.2 0.0067 16.3 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 KXX78096.1 - 0.013 15.0 0.3 0.15 11.7 0.0 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KXX78096.1 - 0.025 13.9 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KXX78096.1 - 0.29 11.4 1.4 0.34 11.2 0.2 1.7 2 0 0 2 2 2 0 TrkA-N domain AP_endonuc_2 PF01261.24 KXX78098.1 - 7.1e-33 113.8 0.1 1e-32 113.3 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.12 KXX78099.1 - 4.6e-44 149.4 0.5 1.3e-43 147.9 0.5 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KXX78099.1 - 1.8e-09 37.6 0.0 1.5e-08 34.7 0.0 2.5 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KXX78099.1 - 5.1e-09 35.9 0.0 2.2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78099.1 - 0.0077 15.5 0.0 0.037 13.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXX78099.1 - 1.9 8.4 6.0 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Aa_trans PF01490.18 KXX78101.1 - 3.6e-84 282.9 32.8 4.3e-84 282.6 32.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.6 KXX78102.1 - 5.8e-22 77.3 0.0 7.3e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXX78102.1 - 9.2e-06 25.0 0.0 2e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.22 KXX78103.1 - 5.3e-23 80.5 0.2 5.9e-23 80.3 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXX78103.1 - 0.05 13.8 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KXX78103.1 - 0.13 12.3 0.0 0.18 12.0 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain DNA_pol_A_exo1 PF01612.20 KXX78104.1 - 2.9e-12 46.7 0.0 4.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.6 KXX78104.1 - 0.037 14.5 0.0 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4786 PF16027.5 KXX78104.1 - 1 9.9 7.5 0.07 13.7 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4786) Peptidase_S49_N PF08496.10 KXX78104.1 - 9.3 6.3 7.8 24 5.0 7.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal WD40 PF00400.32 KXX78105.1 - 7.8e-23 80.3 11.1 7.4e-07 29.8 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat NLE PF08154.12 KXX78105.1 - 3e-16 59.7 0.1 4.9e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KXX78105.1 - 0.00033 19.4 1.2 0.062 11.9 0.1 3.3 2 1 1 4 4 4 2 Nucleoporin Nup120/160 PQQ PF01011.21 KXX78105.1 - 0.08 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat ECH_2 PF16113.5 KXX78106.1 - 2.1e-128 428.6 0.0 3e-128 428.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXX78106.1 - 2.1e-28 99.3 0.0 2.1e-25 89.5 0.0 2.7 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_76 PF03663.14 KXX78107.1 - 2.8e-137 458.1 5.8 3.3e-137 457.9 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NAP PF00956.18 KXX78108.1 - 8.6e-27 94.0 7.3 4.5e-25 88.4 2.6 2.5 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) BUD22 PF09073.10 KXX78108.1 - 0.0028 17.1 15.8 0.004 16.5 15.8 1.2 1 0 0 1 1 1 1 BUD22 EF-hand_9 PF14658.6 KXX78109.1 - 0.076 13.4 0.0 4.9 7.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain RNase_H PF00075.24 KXX78110.1 - 2e-15 57.2 0.0 3.1e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXX78110.1 - 0.00065 19.5 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase-like TetR_C_12 PF16914.5 KXX78110.1 - 0.049 13.7 0.3 0.093 12.9 0.3 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal PilA4 PF18682.1 KXX78111.1 - 1.2 9.6 5.1 0.96 9.9 1.4 2.4 2 0 0 2 2 2 0 Pilin A4 FAD_binding_4 PF01565.23 KXX78112.1 - 2e-22 79.4 0.4 3.7e-22 78.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX78112.1 - 7e-10 38.9 0.2 1.6e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like TPP_enzyme_N PF02776.18 KXX78114.1 - 4.4e-35 120.8 0.1 2.3e-34 118.5 0.2 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXX78114.1 - 2.6e-25 89.0 0.7 2.2e-24 86.0 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXX78114.1 - 1.8e-22 79.5 0.0 3.5e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain 2CSK_N PF08521.10 KXX78115.1 - 0.0055 16.8 0.1 0.014 15.5 0.0 1.5 1 1 1 2 2 2 1 Two-component sensor kinase N-terminal KinB_sensor PF16767.5 KXX78116.1 - 0.069 13.6 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF1996 PF09362.10 KXX78117.1 - 8.4e-46 156.9 0.1 1e-45 156.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) peroxidase PF00141.23 KXX78118.1 - 3.4e-22 79.3 0.0 4.7e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase HTH_17 PF12728.7 KXX78119.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HET PF06985.11 KXX78121.1 - 3e-31 108.8 0.8 3e-31 108.8 0.8 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HATPase_c_3 PF13589.6 KXX78121.1 - 0.00028 20.7 0.2 0.00086 19.1 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DDDD PF10161.9 KXX78122.1 - 0.091 12.5 0.9 9.3 6.1 0.1 3.5 4 0 0 4 4 4 0 Putative mitochondrial precursor protein Laminin_G_3 PF13385.6 KXX78124.1 - 0.0015 18.7 0.1 0.0022 18.2 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Abhydrolase_3 PF07859.13 KXX78125.1 - 7.9e-40 137.0 0.0 9.9e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXX78125.1 - 4e-05 22.7 0.0 6.8e-05 21.9 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 KXX78125.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase tRNA-synt_2 PF00152.20 KXX78126.1 - 7.5e-73 245.3 0.0 1.1e-72 244.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KXX78126.1 - 7.5e-24 84.3 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KXX78126.1 - 9.5e-08 31.9 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXX78126.1 - 0.0072 15.8 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) CorA PF01544.18 KXX78128.1 - 5.9e-06 25.8 7.0 5.9e-06 25.8 7.0 2.6 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Inositol_P PF00459.25 KXX78129.1 - 9.9e-24 84.3 0.3 3e-23 82.7 0.3 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Cellulase PF00150.18 KXX78131.1 - 1.8e-17 63.7 5.1 2.7e-17 63.1 2.9 1.8 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXX78131.1 - 3.9e-08 32.8 0.0 3.8e-07 29.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KXX78131.1 - 0.00063 19.2 0.2 0.003 16.9 0.0 2.0 2 1 0 3 3 3 1 Beta-galactosidase DUF4434 PF14488.6 KXX78131.1 - 0.0019 18.3 0.0 0.059 13.4 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4434) FAD_binding_3 PF01494.19 KXX78132.1 - 7.2e-17 61.7 2.6 5.8e-10 38.9 0.2 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXX78132.1 - 1.1e-08 34.7 0.2 0.00025 20.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX78132.1 - 1.4e-08 34.3 0.0 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX78132.1 - 2.5e-08 33.9 0.9 0.00093 18.9 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX78132.1 - 5.1e-07 28.7 0.3 0.00014 20.7 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KXX78132.1 - 9e-07 29.0 0.1 2.7e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXX78132.1 - 2.9e-05 23.6 0.4 6.3e-05 22.5 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXX78132.1 - 4.1e-05 22.8 0.1 0.0031 16.7 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXX78132.1 - 0.00015 21.1 0.0 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX78132.1 - 0.00077 18.6 0.1 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXX78132.1 - 0.0012 18.2 0.0 0.007 15.7 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXX78132.1 - 0.0046 16.2 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KXX78132.1 - 0.0058 16.0 0.1 1 8.6 0.0 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXX78132.1 - 0.031 14.8 0.0 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXX78132.1 - 0.13 11.1 0.5 0.87 8.4 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.18 KXX78132.1 - 0.18 11.7 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KXX78133.1 - 8e-49 166.6 0.0 1.5e-48 165.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KXX78133.1 - 3.5e-15 56.2 0.0 6.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX78133.1 - 2.6e-05 24.2 0.0 6.1e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Rieske PF00355.26 KXX78134.1 - 0.0078 16.1 0.8 0.46 10.5 0.0 2.6 1 1 1 2 2 2 2 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXX78134.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Oxidored_molyb PF00174.19 KXX78134.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Preseq_ALAS PF09029.10 KXX78135.1 - 0.022 15.2 1.2 0.28 11.7 0.2 2.2 1 1 0 2 2 2 0 5-aminolevulinate synthase presequence Bac_rhodopsin PF01036.18 KXX78136.1 - 2.1e-43 148.5 15.9 2.6e-43 148.2 15.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3792 PF12670.7 KXX78136.1 - 0.006 16.7 12.1 0.1 12.8 1.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3792) Heliorhodopsin PF18761.1 KXX78136.1 - 0.0087 15.4 4.5 0.013 14.9 4.4 1.5 1 1 0 1 1 1 1 Heliorhodopsin DUF202 PF02656.15 KXX78136.1 - 3.5 8.1 16.9 0.48 10.9 5.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MerC PF03203.14 KXX78136.1 - 4.1 7.9 14.9 6.9 7.2 8.9 2.8 2 1 1 3 3 3 0 MerC mercury resistance protein CorA PF01544.18 KXX78138.1 - 4.1e-06 26.3 0.0 6.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MIG-14_Wnt-bd PF06664.12 KXX78138.1 - 0.1 11.8 8.1 7 5.8 7.0 2.2 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion MAT1 PF06391.13 KXX78139.1 - 1.4e-36 126.3 4.1 1.6e-36 126.1 4.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KXX78139.1 - 6.4e-32 109.2 11.2 9.6e-32 108.6 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX78139.1 - 0.00042 20.1 3.7 0.00089 19.1 3.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX78139.1 - 0.00051 19.8 6.3 0.00077 19.3 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX78139.1 - 0.0076 16.1 6.5 0.064 13.1 7.1 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX78139.1 - 0.01 16.2 6.7 0.016 15.5 6.7 1.3 1 0 0 1 1 1 0 Ring finger domain MRP-S26 PF14943.6 KXX78139.1 - 0.013 15.4 14.2 0.013 15.4 14.2 1.5 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-RING_5 PF14634.6 KXX78139.1 - 0.013 15.4 8.8 0.37 10.8 9.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXX78139.1 - 0.091 12.9 5.9 0.38 11.0 5.9 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXX78139.1 - 0.19 11.4 2.1 0.33 10.6 2.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KXX78139.1 - 0.21 11.7 5.6 0.42 10.7 5.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KXX78139.1 - 0.37 10.6 9.9 7 6.5 11.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KXX78139.1 - 2.4 8.4 6.8 6.3 7.1 2.5 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain SUIM_assoc PF16619.5 KXX78139.1 - 4.9 7.3 8.8 12 6.0 8.9 1.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Phos_pyr_kin PF08543.12 KXX78140.1 - 6.6e-11 42.1 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXX78140.1 - 6.7e-06 25.6 0.1 6.3e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 pfkB family carbohydrate kinase PCNA_N PF00705.18 KXX78141.1 - 8.7e-58 193.5 4.5 2.9e-57 191.9 3.8 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KXX78141.1 - 3.3e-51 172.8 0.3 1.8e-50 170.4 0.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KXX78141.1 - 1e-08 35.0 0.1 1.2e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KXX78141.1 - 1.4e-06 27.6 1.6 8.8e-05 21.7 0.6 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KXX78141.1 - 1.9e-05 23.9 0.2 0.0021 17.2 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein DNA_pol3_beta_3 PF02768.15 KXX78141.1 - 0.085 12.7 0.2 0.45 10.4 0.1 2.2 2 1 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Vezatin PF12632.7 KXX78142.1 - 7.2e-77 258.5 0.1 1.3e-76 257.6 0.1 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF2550 PF10739.9 KXX78142.1 - 0.019 15.0 0.0 0.057 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) PET117 PF15786.5 KXX78142.1 - 0.31 11.3 0.1 0.31 11.3 0.1 2.6 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial CENP-F_leu_zip PF10473.9 KXX78142.1 - 1.4 9.0 7.2 0.12 12.4 0.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5ip PF07019.12 KXX78143.1 - 1.7e-31 108.6 7.5 2e-31 108.4 7.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) RL11D PF11088.8 KXX78143.1 - 0.18 12.1 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 GTP_EFTU PF00009.27 KXX78144.1 - 6.8e-09 35.5 0.0 3.9e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF5546 PF17700.1 KXX78144.1 - 0.017 15.5 0.8 0.077 13.4 0.3 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5546) AAA_29 PF13555.6 KXX78144.1 - 0.054 13.2 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KXX78144.1 - 0.11 12.2 0.8 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF948 PF06103.11 KXX78145.1 - 0.34 11.2 9.3 1.5 9.1 2.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FHIPEP PF00771.20 KXX78145.1 - 0.61 8.5 4.0 1.2 7.5 4.0 1.4 1 1 0 1 1 1 0 FHIPEP family OEP PF02321.18 KXX78145.1 - 6.1 6.6 17.1 0.15 11.8 8.4 2.5 1 1 1 2 2 2 0 Outer membrane efflux protein HA2 PF04408.23 KXX78146.1 - 1.4e-20 73.6 1.0 3.2e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXX78146.1 - 2e-13 50.7 0.3 8.4e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXX78146.1 - 3.6e-10 40.0 0.1 2.1e-09 37.6 0.1 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KXX78146.1 - 2.4e-07 31.1 0.0 6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KXX78146.1 - 1.8e-06 27.8 0.0 5.3e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.27 KXX78146.1 - 0.0039 17.7 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KXX78146.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXX78146.1 - 0.18 12.3 1.4 1.9 9.0 0.0 3.1 4 0 0 4 4 4 0 AAA domain Complex1_LYR_2 PF13233.6 KXX78147.1 - 1.2e-18 67.7 0.0 1.5e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXX78147.1 - 3e-11 43.2 0.1 5.7e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KXX78147.1 - 0.016 15.8 0.1 0.024 15.2 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Patatin PF01734.22 KXX78148.1 - 2e-20 73.8 0.0 5.9e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.6 KXX78148.1 - 2.7e-13 50.0 19.4 2.8e-06 27.5 4.2 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat AAA_16 PF13191.6 KXX78148.1 - 5.7e-06 26.8 1.0 5.6e-05 23.6 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KXX78148.1 - 0.0003 20.1 0.1 0.002 17.3 0.0 2.4 3 1 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.6 KXX78148.1 - 0.015 15.6 0.1 0.12 12.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KXX78148.1 - 0.044 14.2 0.0 0.22 12.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX78148.1 - 0.16 11.7 0.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF5311 PF17238.2 KXX78148.1 - 0.17 11.8 0.0 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5311) TPR_8 PF13181.6 KXX78148.1 - 0.39 11.0 2.6 45 4.6 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANTH PF07651.16 KXX78149.1 - 4.4e-72 242.4 0.8 6.1e-72 241.9 0.8 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KXX78149.1 - 4.1e-08 33.3 0.0 7.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Trypan_PARP PF05887.11 KXX78149.1 - 0.051 13.5 4.2 0.13 12.2 4.2 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) tRNA-synt_2 PF00152.20 KXX78150.1 - 9.3e-45 153.0 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2 PF00152.20 KXX78151.1 - 4.6e-35 121.2 0.1 6.3e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXX78151.1 - 0.042 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA_bind PF01588.20 KXX78151.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative tRNA binding domain AXE1 PF05448.12 KXX78151.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CS PF04969.16 KXX78154.1 - 2e-16 60.8 0.0 4.9e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 CS domain Prefoldin_3 PF13758.6 KXX78155.1 - 1.1e-31 108.8 2.6 1.5e-31 108.4 0.8 2.2 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 KXX78155.1 - 3e-25 88.8 11.7 1.4e-23 83.5 0.0 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF3835) MIS13 PF08202.11 KXX78155.1 - 0.0022 17.4 1.3 0.0022 17.4 1.3 2.0 2 1 1 3 3 3 1 Mis12-Mtw1 protein family DUF16 PF01519.16 KXX78155.1 - 2.3 8.8 5.0 1.4 9.4 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function DUF16 RR_TM4-6 PF06459.12 KXX78155.1 - 2.8 7.7 10.9 1.4 8.7 2.3 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Fes1 PF08609.10 KXX78155.1 - 3.1 8.7 5.7 2.6 9.0 1.8 2.9 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 FliJ PF02050.16 KXX78155.1 - 3.2 8.0 7.1 11 6.3 0.0 3.3 3 0 0 3 3 3 0 Flagellar FliJ protein Prefoldin_2 PF01920.20 KXX78155.1 - 4.5 7.3 6.6 7.5 6.6 0.5 3.7 3 0 0 3 3 3 0 Prefoldin subunit TFIIS_M PF07500.14 KXX78156.1 - 2.2e-23 82.9 1.9 3.3e-23 82.3 0.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KXX78156.1 - 2e-18 65.9 6.1 4.2e-18 64.9 6.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KXX78156.1 - 3.7e-11 42.9 0.9 3.7e-11 42.9 0.9 2.3 3 0 0 3 3 3 1 TFIIS helical bundle-like domain DpnD-PcfM PF14207.6 KXX78156.1 - 0.13 12.2 0.3 0.33 10.9 0.3 1.7 1 0 0 1 1 1 0 DpnD/PcfM-like protein LZ3wCH PF18517.1 KXX78156.1 - 0.4 10.8 2.4 1.4 9.0 2.4 1.9 1 0 0 1 1 1 0 Leucine zipper with capping helix domain SpoIIE PF07228.12 KXX78158.1 - 8.5e-13 48.7 0.7 4.8e-11 42.9 0.5 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXX78158.1 - 1.6e-09 37.8 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXX78158.1 - 2.6e-07 30.5 0.8 5.9e-07 29.3 0.8 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C GPI-anchored PF10342.9 KXX78159.1 - 1.7e-12 48.0 0.0 1.7e-12 48.0 0.0 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4512 PF14975.6 KXX78159.1 - 0.9 10.4 5.3 1.4 9.8 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) RCR PF12273.8 KXX78160.1 - 1.1e-09 39.0 24.7 1.5e-08 35.4 24.7 2.3 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red INCENP_N PF12178.8 KXX78161.1 - 0.00096 19.1 2.0 2.5 8.2 0.0 3.7 1 1 2 3 3 3 2 Chromosome passenger complex (CPC) protein INCENP N terminal Apolipoprotein PF01442.18 KXX78161.1 - 0.0083 16.0 0.6 0.01 15.7 0.6 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KXX78161.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Wx5_PLAF3D7 PF09688.10 KXX78161.1 - 0.016 15.2 0.2 0.71 9.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) TryThrA_C PF12319.8 KXX78161.1 - 0.057 12.9 0.2 0.077 12.5 0.2 1.1 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal ApoLp-III PF07464.11 KXX78161.1 - 0.058 13.5 0.4 0.21 11.7 0.4 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) tRNA-synt_2c PF01411.19 KXX78162.1 - 6e-212 705.0 0.1 1.6e-211 703.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXX78162.1 - 1e-16 60.7 0.2 2.7e-16 59.4 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KXX78162.1 - 4.7e-14 53.0 4.1 9.6e-14 52.0 2.7 2.4 3 0 0 3 3 3 1 DHHA1 domain AviRa PF11599.8 KXX78162.1 - 0.15 11.5 1.2 0.34 10.3 1.2 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa PAT1 PF09770.9 KXX78163.1 - 0.066 11.5 4.7 0.067 11.5 4.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PALP PF00291.25 KXX78164.1 - 4.8e-63 213.3 2.2 5.9e-63 213.0 2.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 KXX78165.1 - 1.4e-40 139.6 0.0 2.3e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KXX78165.1 - 2.1e-05 24.5 0.0 6.2e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase NAD_binding_8 PF13450.6 KXX78167.1 - 3.3e-11 43.2 0.0 9.5e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXX78167.1 - 7.9e-10 37.8 0.0 3.8e-09 35.5 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXX78167.1 - 0.00013 21.4 0.0 0.049 12.9 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXX78167.1 - 0.00019 20.7 0.0 0.057 12.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXX78167.1 - 0.0002 21.3 0.0 0.01 15.8 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding F-box-like PF12937.7 KXX78168.1 - 1e-10 41.4 0.2 2.6e-10 40.0 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXX78168.1 - 5e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KXX78168.1 - 0.066 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain MBOAT PF03062.19 KXX78169.1 - 1.1e-44 153.3 11.9 2.2e-44 152.3 11.9 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Cation_efflux PF01545.21 KXX78170.1 - 1.5e-49 168.5 9.5 6.6e-49 166.3 9.5 1.8 1 1 0 1 1 1 1 Cation efflux family Lipase_GDSL_2 PF13472.6 KXX78171.1 - 0.00046 20.6 0.6 0.007 16.8 0.2 2.3 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family FANCM-MHF_bd PF16783.5 KXX78171.1 - 0.17 11.9 0.0 0.52 10.4 0.0 1.6 1 1 1 2 2 2 0 FANCM to MHF binding domain Cu-oxidase_2 PF07731.14 KXX78172.1 - 3.3e-40 137.0 7.3 1.4e-38 131.7 0.6 3.6 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXX78172.1 - 1.4e-39 134.8 2.5 1.4e-39 134.8 2.5 2.7 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KXX78172.1 - 2e-34 119.0 0.0 4.9e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Catalase PF00199.19 KXX78173.1 - 2.7e-171 569.9 0.2 3.4e-171 569.5 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXX78173.1 - 6.3e-21 74.4 0.0 1.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KXX78173.1 - 1.1e-08 34.8 0.2 2.2e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KXX78173.1 - 5.1e-08 32.9 0.1 8.5e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family AAA_5 PF07728.14 KXX78174.1 - 8.5e-08 32.3 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXX78174.1 - 0.00016 21.8 0.0 0.29 11.2 0.1 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 KXX78174.1 - 0.00044 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Torsin PF06309.11 KXX78174.1 - 0.0023 18.0 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA PF00004.29 KXX78174.1 - 0.0028 18.1 0.0 0.0057 17.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX78174.1 - 0.0081 16.6 0.3 1.4 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 KXX78174.1 - 0.11 11.9 0.1 0.87 8.9 0.1 2.2 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KXX78174.1 - 0.18 12.1 0.0 0.65 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain SET PF00856.28 KXX78175.1 - 2.8e-07 31.1 0.0 6.5e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 SET domain TPR_10 PF13374.6 KXX78175.1 - 0.059 13.3 1.1 0.14 12.1 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Beta-lactamase PF00144.24 KXX78177.1 - 1.2e-22 80.6 0.5 1.9e-22 80.0 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase CLLAC PF15675.5 KXX78177.1 - 0.15 11.6 2.8 0.31 10.6 2.8 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain Metallophos_2 PF12850.7 KXX78178.1 - 3.2e-06 27.4 0.1 0.00026 21.2 0.0 2.5 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KXX78178.1 - 5.2e-05 23.8 0.0 9.7e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Transp_inhibit PF18791.1 KXX78178.1 - 0.0069 15.9 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Transport inhibitor response 1 protein domain EF-1_beta_acid PF10587.9 KXX78178.1 - 0.21 12.1 3.7 0.39 11.2 3.7 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF1308 PF07000.11 KXX78181.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KXX78181.1 - 0.16 11.3 0.0 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5614) Exc PF07825.11 KXX78181.1 - 0.18 11.8 0.6 2.2 8.3 0.1 2.9 2 1 1 3 3 3 0 Excisionase-like protein NmrA PF05368.13 KXX78182.1 - 1.5e-37 129.4 0.0 1.9e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX78182.1 - 1.9e-19 70.3 0.0 3.7e-19 69.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX78182.1 - 2.3e-06 27.3 0.0 7.2e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX78182.1 - 0.015 14.8 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Inj_translocase PF16928.5 KXX78182.1 - 0.038 13.4 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome 3Beta_HSD PF01073.19 KXX78182.1 - 0.045 12.8 0.0 0.092 11.7 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXX78182.1 - 0.11 11.6 0.4 0.54 9.3 0.1 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.18 KXX78182.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_61 PF03443.14 KXX78183.1 - 2.9e-61 207.0 0.0 3.6e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.21 KXX78184.1 - 1.2e-105 353.8 41.8 1.5e-105 353.6 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX78184.1 - 1.1e-29 103.5 45.7 1.5e-29 103.1 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.24 KXX78186.1 - 5.8e-27 95.2 0.0 1e-26 94.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Laminin_II PF06009.12 KXX78186.1 - 0.00017 21.6 3.0 0.00033 20.7 3.0 1.4 1 0 0 1 1 1 1 Laminin Domain II NAD_binding_8 PF13450.6 KXX78186.1 - 0.003 17.8 0.1 0.008 16.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF812 PF05667.11 KXX78186.1 - 0.0034 16.3 0.0 0.0045 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FliJ PF02050.16 KXX78186.1 - 0.005 17.1 1.9 0.005 17.1 1.9 1.7 2 0 0 2 2 1 1 Flagellar FliJ protein DUF1664 PF07889.12 KXX78186.1 - 0.0088 16.1 5.6 0.019 15.0 5.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXX78186.1 - 0.0091 14.9 0.9 0.015 14.2 0.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec8_exocyst PF04048.14 KXX78186.1 - 0.013 15.3 1.7 0.023 14.6 0.9 1.7 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 KXX78186.1 - 0.017 15.2 3.1 0.032 14.3 3.1 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin PF00261.20 KXX78186.1 - 0.018 14.5 1.9 0.034 13.5 1.9 1.3 1 0 0 1 1 1 0 Tropomyosin CENP-F_leu_zip PF10473.9 KXX78186.1 - 0.021 14.9 1.3 0.046 13.7 1.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 KXX78186.1 - 0.025 14.9 4.7 0.053 13.8 4.7 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) WEMBL PF05701.11 KXX78186.1 - 0.032 12.9 0.6 0.049 12.3 0.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF4763 PF15960.5 KXX78186.1 - 0.039 13.3 0.6 0.14 11.4 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) ZapB PF06005.12 KXX78186.1 - 0.044 14.2 4.6 0.093 13.2 4.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Noelin-1 PF12308.8 KXX78186.1 - 0.048 13.7 0.4 0.1 12.6 0.4 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein HrpB7 PF09486.10 KXX78186.1 - 0.049 14.0 0.8 0.13 12.7 0.8 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ApbA PF02558.16 KXX78186.1 - 0.05 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TMPIT PF07851.13 KXX78186.1 - 0.092 12.0 1.6 0.14 11.4 1.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 KXX78186.1 - 0.095 13.1 7.3 0.25 11.7 7.2 1.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Pyr_redox_2 PF07992.14 KXX78186.1 - 0.1 11.8 0.1 0.5 9.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AKNA PF12443.8 KXX78186.1 - 0.11 13.2 0.5 0.21 12.2 0.5 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor YabA PF06156.13 KXX78186.1 - 0.12 13.0 1.0 0.25 12.0 1.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF4618 PF15397.6 KXX78186.1 - 0.17 11.3 4.1 0.31 10.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4446 PF14584.6 KXX78186.1 - 0.21 11.6 1.1 0.4 10.6 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) LPP PF04728.13 KXX78186.1 - 0.22 11.9 3.5 0.56 10.6 3.5 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper APG6_N PF17675.1 KXX78186.1 - 0.22 12.0 1.5 0.26 11.8 0.1 1.8 2 0 0 2 2 1 0 Apg6 coiled-coil region DUF745 PF05335.13 KXX78186.1 - 0.23 11.2 2.3 0.39 10.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Cluap1 PF10234.9 KXX78186.1 - 0.27 10.6 2.8 0.44 9.9 2.8 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF724 PF05266.14 KXX78186.1 - 0.27 11.0 2.3 0.45 10.3 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2730 PF10805.8 KXX78186.1 - 0.41 10.8 1.8 1.1 9.4 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) EzrA PF06160.12 KXX78186.1 - 0.41 8.8 2.8 0.6 8.2 2.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Filament PF00038.21 KXX78186.1 - 0.48 10.0 5.2 0.41 10.2 3.3 1.7 2 0 0 2 2 2 0 Intermediate filament protein HIP1_clath_bdg PF16515.5 KXX78186.1 - 0.58 10.8 5.1 1.2 9.8 5.1 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Gp58 PF07902.11 KXX78186.1 - 0.63 8.3 4.7 1.1 7.5 4.7 1.2 1 0 0 1 1 1 0 gp58-like protein IFT57 PF10498.9 KXX78186.1 - 0.74 8.7 5.3 1.4 7.8 5.3 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DivIC PF04977.15 KXX78186.1 - 0.75 9.6 5.3 1.7 8.4 5.3 1.6 1 0 0 1 1 1 0 Septum formation initiator NPV_P10 PF05531.12 KXX78186.1 - 3 8.4 10.9 2.9 8.4 8.2 2.3 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Macoilin PF09726.9 KXX78188.1 - 0.031 12.8 0.0 0.031 12.8 0.0 1.4 2 0 0 2 2 2 0 Macoilin family DuoxA PF10204.9 KXX78188.1 - 0.049 12.6 0.1 0.076 12.0 0.1 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor HSP20 PF00011.21 KXX78190.1 - 2.6e-17 62.8 0.0 1.4e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXX78190.1 - 0.0015 18.0 0.0 0.053 13.1 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Mucin PF01456.17 KXX78190.1 - 5.2 7.1 8.6 9.7 6.2 8.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Abhydrolase_6 PF12697.7 KXX78192.1 - 1.2e-16 62.0 4.5 1.5e-16 61.7 4.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX78192.1 - 2e-15 57.2 0.0 8.6e-14 51.8 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX78192.1 - 1.3e-09 37.7 1.3 2.1e-09 37.0 1.3 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 TetR_C_6 PF13977.6 KXX78192.1 - 0.029 14.6 0.8 0.44 10.8 0.0 2.3 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Myb_DNA-binding PF00249.31 KXX78194.1 - 3e-05 24.1 0.0 6.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXX78194.1 - 0.0012 19.0 0.3 0.0024 18.1 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KXX78194.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CBM65_1 PF18259.1 KXX78194.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding module 65 domain 1 SET PF00856.28 KXX78195.1 - 7.2e-06 26.5 0.0 3.1e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 SET domain EHN PF06441.12 KXX78196.1 - 9.7e-24 83.8 0.1 1.7e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXX78196.1 - 4.1e-05 23.3 0.0 7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M28 PF04389.17 KXX78198.1 - 2e-34 119.0 0.0 2.8e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXX78198.1 - 7.4e-10 38.7 0.1 1.6e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXX78198.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 PDDEXK_6 PF04720.12 KXX78198.1 - 0.062 13.2 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function NUDIX PF00293.28 KXX78199.1 - 1.6e-14 54.1 0.8 5.8e-14 52.3 0.3 1.9 2 0 0 2 2 2 1 NUDIX domain SLT PF01464.20 KXX78201.1 - 6.8e-07 29.0 0.9 5.2e-06 26.1 0.9 2.0 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 KXX78201.1 - 0.0019 17.9 1.4 0.0043 16.8 1.4 1.5 1 1 0 1 1 1 1 Lysozyme-like Glyco_hydro_7 PF00840.20 KXX78202.1 - 4.9e-147 490.2 6.9 6.1e-147 489.8 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Peptidase_S28 PF05577.12 KXX78203.1 - 2.1e-43 148.7 0.2 1.5e-42 145.9 0.2 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 KXX78203.1 - 0.0013 18.0 0.1 0.0019 17.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 KXX78203.1 - 0.0043 16.5 0.1 0.0072 15.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXX78203.1 - 0.039 13.6 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative esterase DUF1996 PF09362.10 KXX78205.1 - 1.7e-78 263.9 0.3 2.1e-78 263.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ComA PF02679.15 KXX78206.1 - 9.3e-94 313.4 0.0 1.1e-93 313.2 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) ADH_zinc_N PF00107.26 KXX78209.1 - 1.2e-09 38.2 0.7 2.1e-09 37.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX78209.1 - 2.2e-08 33.9 0.0 4.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXX78209.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Fungal_trans PF04082.18 KXX78210.1 - 0.008 15.2 0.2 0.079 12.0 0.1 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain zf-Sec23_Sec24 PF04810.15 KXX78210.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Fungal_trans PF04082.18 KXX78211.1 - 4e-11 42.4 0.0 7.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX78211.1 - 8.7e-11 41.8 12.2 1.6e-10 41.0 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_6 PF00970.24 KXX78212.1 - 5.9e-30 103.6 0.0 9.3e-30 102.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXX78212.1 - 3.2e-29 101.8 0.0 4.5e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXX78212.1 - 0.00032 20.9 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ZapB PF06005.12 KXX78213.1 - 0.00042 20.7 8.3 0.099 13.1 0.1 2.6 2 0 0 2 2 2 2 Cell division protein ZapB DUF4686 PF15742.5 KXX78213.1 - 0.009 15.2 16.1 0.013 14.7 16.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) bZIP_1 PF00170.21 KXX78213.1 - 0.0096 16.0 13.6 0.17 12.0 1.9 2.8 1 1 0 2 2 2 2 bZIP transcription factor BLOC1_2 PF10046.9 KXX78213.1 - 0.061 13.6 8.5 0.28 11.5 3.3 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 KXX78213.1 - 0.16 12.2 12.3 0.081 13.1 9.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KXX78213.1 - 0.17 11.3 14.8 1.4 8.2 7.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KXX78213.1 - 0.22 11.6 16.8 0.14 12.3 8.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 KXX78213.1 - 0.31 10.9 6.6 0.56 10.1 1.7 2.4 1 1 1 2 2 2 0 Sec34-like family APG6_N PF17675.1 KXX78213.1 - 0.35 11.4 20.4 0.13 12.8 14.9 2.6 1 1 2 3 3 3 0 Apg6 coiled-coil region HALZ PF02183.18 KXX78213.1 - 0.45 10.8 9.3 6.5 7.1 3.2 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper CLZ PF16526.5 KXX78213.1 - 0.5 10.8 9.7 0.12 12.8 3.7 3.0 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 KXX78213.1 - 0.64 8.8 15.9 0.73 8.6 9.3 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KXX78213.1 - 0.66 10.2 17.8 1.3 9.2 17.8 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KXX78213.1 - 0.66 9.8 16.4 0.042 13.7 8.4 2.4 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF2968 PF11180.8 KXX78213.1 - 0.86 9.2 10.9 0.8 9.3 9.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DASH_Dad3 PF08656.10 KXX78213.1 - 0.98 9.5 3.8 9.6 6.4 3.8 2.4 1 1 0 1 1 1 0 DASH complex subunit Dad3 Brr6_like_C_C PF10104.9 KXX78213.1 - 1.3 8.8 3.5 2.5 7.9 3.5 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Jnk-SapK_ap_N PF09744.9 KXX78213.1 - 1.5 9.0 18.6 5.8 7.1 6.7 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 UPF0449 PF15136.6 KXX78213.1 - 1.6 9.3 11.8 1.2 9.7 4.4 2.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF4472 PF14739.6 KXX78213.1 - 1.8 9.3 14.3 20 5.9 2.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) FUSC PF04632.12 KXX78213.1 - 3.6 6.0 4.8 4.6 5.7 4.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 KXX78213.1 - 4.8 7.9 10.7 31 5.3 6.0 3.0 2 1 0 2 2 2 0 Initiation control protein YabA FapA PF03961.13 KXX78213.1 - 7.4 5.1 9.4 14 4.2 9.3 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A 2OG-FeII_Oxy_3 PF13640.6 KXX78214.1 - 1.3e-07 32.4 0.1 2.2e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Croc_4 PF17691.1 KXX78215.1 - 9.3 6.3 9.7 3.6 7.6 3.3 3.1 2 1 1 3 3 3 0 Contingent replication of cDNA 4 p450 PF00067.22 KXX78218.1 - 2.2e-37 128.9 0.0 3.1e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SidE PF12252.8 KXX78219.1 - 0.35 8.4 0.0 0.38 8.2 0.0 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein Lipase_GDSL_2 PF13472.6 KXX78220.1 - 4.8e-16 59.7 0.3 6.9e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX78220.1 - 1.4e-09 38.2 0.0 2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 KXX78220.1 - 0.028 13.7 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 OSK domain DUF872 PF05915.12 KXX78221.1 - 0.026 14.7 0.4 0.026 14.7 0.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) UL42 PF17638.2 KXX78221.1 - 0.029 14.4 0.1 0.029 14.4 0.1 2.4 2 1 0 2 2 2 0 HCMV UL42 DUF2085 PF09858.9 KXX78221.1 - 0.047 14.2 0.8 0.047 14.2 0.8 3.5 2 2 1 3 3 3 0 Predicted membrane protein (DUF2085) DUF1772 PF08592.11 KXX78221.1 - 2.7 8.3 13.5 4.9 7.5 3.6 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) CN_hydrolase PF00795.22 KXX78222.1 - 1.6e-50 171.9 0.0 1.7e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase STE2 PF02116.15 KXX78223.1 - 2.7e-91 305.8 21.3 3.2e-91 305.5 21.3 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.13 KXX78224.1 - 4.9e-37 126.5 0.1 8.1e-37 125.8 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KXX78224.1 - 6.1e-22 77.3 0.8 1.6e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 KXX78224.1 - 0.011 15.3 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme CCDC24 PF15669.5 KXX78224.1 - 0.042 13.7 0.3 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family IDO PF01231.18 KXX78225.1 - 1.1e-167 558.3 0.0 1.3e-167 558.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Serine_protease PF18405.1 KXX78226.1 - 0.17 11.0 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease TFB6 PF17110.5 KXX78228.1 - 1e-67 227.1 0.0 1.3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH HgmA PF04209.13 KXX78229.1 - 4.8e-189 628.5 0.0 5.7e-189 628.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase IPU_b_solenoid PF18783.1 KXX78230.1 - 0.09 12.8 0.4 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat Methyltransf_23 PF13489.6 KXX78232.1 - 7.5e-26 90.9 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX78232.1 - 1.7e-14 54.3 0.0 4.4e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX78232.1 - 3.2e-12 46.9 0.0 6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX78232.1 - 5.1e-12 46.4 0.0 1.4e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX78232.1 - 3.9e-11 43.0 0.0 3.1e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX78232.1 - 1.1e-05 24.9 0.0 7.2e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXX78232.1 - 6.5e-05 22.3 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KXX78232.1 - 0.0031 17.6 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXX78232.1 - 0.0051 16.3 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.12 KXX78232.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KXX78232.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 KXX78232.1 - 0.039 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 KXX78232.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXX78232.1 - 0.21 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S15 PF02129.18 KXX78233.1 - 1.6e-41 142.7 0.4 2.3e-41 142.2 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXX78233.1 - 1.9e-39 135.9 0.0 2.9e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KXX78233.1 - 0.029 13.6 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CoA_transf_3 PF02515.17 KXX78235.1 - 3.3e-39 135.0 2.4 5e-38 131.2 1.5 2.1 2 0 0 2 2 2 2 CoA-transferase family III NRBF2 PF08961.10 KXX78236.1 - 0.7 9.5 3.5 1.2 8.7 0.0 2.0 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DEAD PF00270.29 KXX78237.1 - 7.3e-24 84.5 0.1 7e-23 81.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX78237.1 - 1.7e-18 67.0 1.1 1e-15 58.0 0.1 3.5 4 0 0 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.15 KXX78237.1 - 0.00022 21.3 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 KXX78237.1 - 0.00071 20.2 0.0 0.0018 19.0 0.0 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Tnp_P_element PF12017.8 KXX78237.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Transposase protein DUF3176 PF11374.8 KXX78238.1 - 0.98 9.6 5.2 0.3 11.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) AA_permease PF00324.21 KXX78240.1 - 8e-127 423.7 41.0 9.5e-127 423.5 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX78240.1 - 2.8e-29 102.2 43.1 4.6e-29 101.5 43.1 1.3 1 0 0 1 1 1 1 Amino acid permease Cytochrome-c551 PF10643.9 KXX78240.1 - 0.024 14.2 2.6 0.052 13.1 2.6 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Rubis-subs-bind PF09273.11 KXX78241.1 - 5.7e-23 82.0 0.0 9e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KXX78241.1 - 5.9e-15 56.1 0.0 1.1e-14 55.2 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KXX78241.1 - 4e-10 39.6 11.0 7e-10 38.8 11.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXX78241.1 - 1.1 9.6 7.9 2.2 8.7 7.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding His_Phos_1 PF00300.22 KXX78243.1 - 5e-20 72.0 0.0 6.4e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HET PF06985.11 KXX78244.1 - 1.6e-30 106.4 0.0 2.6e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mso1_C PF14477.6 KXX78244.1 - 0.2 12.1 0.8 0.46 10.9 0.8 1.5 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 STE3 PF02076.15 KXX78245.1 - 0.2 10.8 6.1 0.26 10.4 5.6 1.4 1 1 0 1 1 1 0 Pheromone A receptor EphA2_TM PF14575.6 KXX78245.1 - 1.2 10.1 3.5 1.2e+02 3.7 1.7 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Acyl_transf_3 PF01757.22 KXX78245.1 - 1.5 7.8 16.1 0.064 12.3 6.8 2.0 1 1 0 2 2 2 0 Acyltransferase family DUF805 PF05656.14 KXX78245.1 - 5.3 7.5 9.6 0.59 10.6 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF805) ECSCR PF15820.5 KXX78245.1 - 8.7 6.2 5.7 4.5 7.1 0.6 2.6 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator DUF2070 PF09843.9 KXX78245.1 - 9.2 4.4 12.1 12 4.1 12.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) WD40 PF00400.32 KXX78246.1 - 7.7e-11 42.4 3.2 1.3e-07 32.2 0.0 3.1 3 0 0 3 3 2 2 WD domain, G-beta repeat HET PF06985.11 KXX78246.1 - 1.7e-10 41.5 6.9 9.9e-09 35.7 0.0 3.2 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KXX78246.1 - 7.4e-07 29.4 0.0 8.1e-06 26.1 0.0 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.7 KXX78246.1 - 5e-05 23.8 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX78246.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX78246.1 - 0.0018 18.6 0.0 0.0066 16.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 KXX78246.1 - 0.0027 18.1 0.0 0.013 15.9 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 KXX78246.1 - 0.005 17.4 0.0 0.015 15.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) APG6_N PF17675.1 KXX78246.1 - 0.037 14.5 15.4 0.063 13.8 15.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KXX78246.1 - 0.067 11.1 3.8 0.095 10.6 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup160 PF11715.8 KXX78246.1 - 0.083 11.5 0.1 2.1 6.9 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 FlaC_arch PF05377.11 KXX78246.1 - 0.13 12.6 6.7 0.28 11.6 6.7 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Me-amine-dh_H PF06433.11 KXX78246.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) FTA4 PF13093.6 KXX78246.1 - 0.3 11.0 6.7 0.5 10.2 6.7 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF724 PF05266.14 KXX78246.1 - 0.52 10.1 11.4 3.6 7.4 12.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CENP-H PF05837.12 KXX78246.1 - 2.7 8.4 12.6 4.9 7.6 12.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 KXX78246.1 - 3.5 7.5 7.4 9 6.1 7.4 1.7 1 0 0 1 1 1 0 Septum formation initiator GMC_oxred_N PF00732.19 KXX78247.1 - 3.2e-43 148.2 0.9 4.2e-43 147.8 0.9 1.1 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXX78247.1 - 0.057 13.7 0.2 0.23 11.7 0.2 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXX78247.1 - 0.22 10.7 0.9 0.34 10.1 0.2 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KXX78247.1 - 0.26 10.5 2.2 0.7 9.1 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 KXX78248.1 - 2.2e-29 101.8 11.0 1.7e-13 51.0 0.6 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX78248.1 - 1.6e-16 60.4 10.9 8.1e-08 32.7 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX78248.1 - 1.2e-15 57.4 8.6 1.5e-06 28.3 0.4 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX78248.1 - 3e-15 54.8 3.2 0.0012 19.2 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KXX78248.1 - 1.1e-11 44.6 10.2 5.1e-05 23.5 0.2 4.3 4 0 0 4 4 4 3 Ankyrin repeat UPF1_Zn_bind PF09416.10 KXX78248.1 - 0.19 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) MFS_1 PF07690.16 KXX78249.1 - 2.7e-22 79.2 57.9 1.4e-20 73.5 56.3 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX78249.1 - 0.00075 18.0 24.8 0.00075 18.0 24.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 KXX78249.1 - 0.0094 16.1 0.6 0.0094 16.1 0.6 2.7 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 Kelch_4 PF13418.6 KXX78250.1 - 4.7e-16 58.5 8.7 0.0006 19.8 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXX78250.1 - 2.5e-09 37.2 9.7 0.0044 17.3 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KXX78250.1 - 2.6e-09 36.9 4.1 0.099 12.7 0.1 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 KXX78250.1 - 3.3e-08 33.5 9.9 0.58 10.5 0.0 5.6 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KXX78250.1 - 4e-06 26.6 7.8 0.56 10.3 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 KXX78250.1 - 0.0019 17.8 4.5 0.12 12.0 0.0 4.1 3 1 1 4 4 4 1 Kelch motif PQQ_3 PF13570.6 KXX78250.1 - 0.072 13.6 0.5 0.072 13.6 0.5 3.4 3 0 0 3 3 3 0 PQQ-like domain Peptidase_M4_C PF02868.15 KXX78251.1 - 7.1e-41 139.9 0.0 1.1e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KXX78251.1 - 1.3e-23 84.1 0.2 2.4e-23 83.2 0.2 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 KXX78251.1 - 2e-06 27.4 0.0 0.01 15.6 0.0 2.4 2 0 0 2 2 2 2 Protealysin propeptide NACHT PF05729.12 KXX78252.1 - 8.4e-07 29.0 0.1 0.062 13.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KXX78252.1 - 0.00048 20.7 0.1 0.17 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXX78252.1 - 0.0012 19.2 0.0 0.009 16.3 0.0 2.5 2 2 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KXX78252.1 - 0.0017 18.9 0.0 0.0082 16.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 KXX78252.1 - 0.0025 18.4 0.1 0.057 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX78252.1 - 0.0025 18.2 0.2 0.044 14.2 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KXX78252.1 - 0.004 16.9 0.1 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 KXX78252.1 - 0.0042 17.0 0.1 0.59 10.0 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KXX78252.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Seryl_tRNA_N PF02403.22 KXX78252.1 - 0.019 15.2 2.4 0.13 12.5 2.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RNA_helicase PF00910.22 KXX78252.1 - 0.056 13.8 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 KXX78252.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase IF2_N PF04760.15 KXX78252.1 - 0.082 12.7 0.2 0.082 12.7 0.2 2.5 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Ploopntkinase3 PF18751.1 KXX78252.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 KXX78252.1 - 0.15 12.2 0.0 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Takusan PF04822.13 KXX78252.1 - 0.17 11.8 0.8 0.52 10.2 0.8 1.9 1 0 0 1 1 1 0 Takusan NYD-SP28_assoc PF14775.6 KXX78252.1 - 4.5 7.4 5.6 1.9 8.7 0.9 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain Gaa1 PF04114.14 KXX78253.1 - 2.8e-170 567.6 0.0 2.8e-170 567.6 0.0 1.4 2 0 0 2 2 2 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 KXX78253.1 - 2.4e-13 50.3 10.7 2.4e-13 50.3 10.7 3.1 4 1 0 4 4 4 1 Rhomboid family Gemini_mov PF01708.16 KXX78253.1 - 7.5 6.4 0.0 7.5 6.4 0.0 3.3 4 0 0 4 4 4 0 Geminivirus putative movement protein PCI PF01399.27 KXX78254.1 - 2.8e-10 40.7 0.0 7.5e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KXX78254.1 - 1.8e-06 27.4 3.2 3.6e-06 26.5 3.2 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 KXX78254.1 - 0.036 13.6 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) zf-C2H2_jaz PF12171.8 KXX78255.1 - 7.4e-10 38.9 0.4 1.2e-09 38.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KXX78255.1 - 0.026 14.3 0.2 0.051 13.3 0.1 1.6 2 0 0 2 2 2 0 U1 zinc finger zf-SCNM1 PF15803.5 KXX78255.1 - 0.045 13.4 0.2 0.082 12.6 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 Tna_leader PF08053.11 KXX78255.1 - 0.21 11.6 0.1 0.36 10.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophanase operon leader peptide Aconitase PF00330.20 KXX78256.1 - 3.8e-149 497.6 0.0 4.9e-149 497.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXX78256.1 - 3.4e-43 147.1 0.0 6.4e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain N6-adenineMlase PF10237.9 KXX78257.1 - 4.9e-51 172.7 0.0 6.6e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase UCH PF00443.29 KXX78258.1 - 1.4e-50 172.2 1.7 2e-50 171.7 1.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX78258.1 - 7.5e-33 114.5 3.4 1.2e-32 113.8 3.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXX78258.1 - 0.0023 18.2 0.5 0.0023 18.2 0.5 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein NmrA PF05368.13 KXX78259.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXX78259.1 - 2.2e-16 60.1 0.1 1e-15 57.8 0.1 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX78259.1 - 1.3e-14 54.5 0.0 2.1e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXX78259.1 - 4.5e-11 42.3 0.1 1.1e-10 41.0 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXX78259.1 - 3.6e-10 39.8 0.2 1.9e-09 37.4 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXX78259.1 - 1.9e-06 27.2 0.0 5e-05 22.5 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXX78259.1 - 8.6e-06 25.3 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXX78259.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 KXX78259.1 - 0.00073 19.2 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX78259.1 - 0.0013 18.7 0.0 0.36 10.7 0.0 2.8 3 0 0 3 3 3 1 KR domain NAD_binding_4 PF07993.12 KXX78259.1 - 0.0016 17.7 0.7 0.28 10.3 0.3 3.1 2 1 1 3 3 3 1 Male sterility protein NAD_binding_2 PF03446.15 KXX78259.1 - 0.063 13.4 0.0 0.23 11.6 0.0 1.9 2 1 1 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_11 PF08241.12 KXX78260.1 - 4.8e-10 39.9 0.0 7.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX78260.1 - 4.8e-08 33.6 0.0 1.1e-07 32.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX78260.1 - 1.6e-05 24.8 0.0 1.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX78260.1 - 0.004 17.9 0.0 0.0059 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX78260.1 - 0.052 12.9 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXX78260.1 - 0.095 12.5 0.0 0.44 10.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain BLACT_WH PF17778.1 KXX78261.1 - 1.9e-18 66.1 0.0 4.9e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KXX78261.1 - 2.4e-18 66.9 6.8 1.3e-16 61.2 6.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXX78261.1 - 4.7e-07 29.5 0.3 7.8e-07 28.8 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ytp1 PF10355.9 KXX78262.1 - 2.2e-120 401.1 5.4 3e-120 400.6 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXX78262.1 - 4.8e-33 113.1 11.0 2.9e-32 110.6 1.5 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) TMEM100 PF16311.5 KXX78262.1 - 0.16 11.5 2.2 2.6 7.6 0.1 3.0 3 0 0 3 3 3 0 Transmembrane protein 100 Ca_hom_mod PF14798.6 KXX78262.1 - 0.19 10.8 0.1 0.19 10.8 0.1 2.1 3 0 0 3 3 3 0 Calcium homeostasis modulator Metallopep PF12044.8 KXX78263.1 - 1.6e-168 560.8 0.0 2e-168 560.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KXX78263.1 - 4.3e-06 26.7 0.0 7.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M10 PF00413.24 KXX78263.1 - 0.0028 17.5 0.0 0.0065 16.3 0.0 1.6 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KXX78263.1 - 0.22 10.4 0.5 0.38 9.7 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 W2 PF02020.18 KXX78264.1 - 1.1e-19 70.3 3.9 1.1e-19 70.3 3.9 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KXX78264.1 - 1.4e-09 37.3 11.6 0.00012 21.7 1.3 5.2 3 1 3 6 6 6 5 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXX78264.1 - 8.3e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KXX78264.1 - 0.00058 18.1 0.6 0.0014 16.8 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KXX78264.1 - 0.025 13.5 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 L-fucokinase NTP_transf_3 PF12804.7 KXX78264.1 - 0.029 14.7 0.0 0.082 13.3 0.0 1.9 1 0 0 1 1 1 0 MobA-like NTP transferase domain Cwf_Cwc_15 PF04889.12 KXX78264.1 - 1.3 8.7 14.1 0.02 14.7 6.0 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 KXX78264.1 - 7.6 4.7 10.8 11 4.2 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Whi5 PF08528.11 KXX78265.1 - 2.4e-07 30.2 0.3 5.3e-07 29.1 0.3 1.6 1 0 0 1 1 1 1 Whi5 like SF-assemblin PF06705.11 KXX78265.1 - 0.023 14.1 0.3 0.034 13.5 0.3 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF1839 PF08893.10 KXX78265.1 - 0.11 11.6 0.4 0.16 11.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) I-set PF07679.16 KXX78266.1 - 5.6e-05 23.1 0.0 10 6.3 0.1 5.6 5 0 0 5 5 5 1 Immunoglobulin I-set domain DUF1918 PF08940.11 KXX78266.1 - 0.027 14.1 1.0 38 4.0 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1918) SKG6 PF08693.10 KXX78267.1 - 0.00058 19.2 2.9 0.00058 19.2 2.9 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Extensin_2 PF04554.13 KXX78269.1 - 0.31 11.1 37.3 0.54 10.4 37.3 1.5 1 1 0 1 1 1 0 Extensin-like region HAD_SAK_1 PF10307.9 KXX78270.1 - 4e-77 258.6 0.0 5.9e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins PAS_9 PF13426.7 KXX78271.1 - 4.9e-23 81.4 0.0 5.9e-17 61.8 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KXX78271.1 - 1.2e-19 70.4 0.0 3.7e-10 39.9 0.0 3.8 4 0 0 4 4 4 3 PAS fold GATA PF00320.27 KXX78271.1 - 3.8e-14 52.0 7.9 8.2e-14 50.9 7.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KXX78271.1 - 8e-14 51.6 0.1 2.9e-06 27.3 0.0 4.3 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.10 KXX78271.1 - 8.6e-07 29.2 0.0 0.17 12.1 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KXX78271.1 - 0.00018 21.6 0.0 0.015 15.4 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KXX78271.1 - 0.06 13.4 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 PAS domain Peptidase_C14 PF00656.22 KXX78272.1 - 1.3e-64 218.5 0.0 1.6e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain HSF_DNA-bind PF00447.17 KXX78273.1 - 4.5e-32 110.5 1.9 8.6e-32 109.6 1.9 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KXX78273.1 - 1.3e-24 86.5 0.4 3e-24 85.4 0.4 1.6 1 0 0 1 1 1 1 Response regulator receiver domain CENP-H PF05837.12 KXX78273.1 - 0.0093 16.4 5.2 0.018 15.5 5.2 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) CENP-Q PF13094.6 KXX78273.1 - 0.016 15.4 1.3 0.033 14.4 1.3 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Dad2 PF08654.10 KXX78273.1 - 0.057 13.8 0.6 1.2 9.6 0.5 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 Mod_r PF07200.13 KXX78273.1 - 0.076 13.1 2.9 0.15 12.2 2.9 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KXX78273.1 - 0.09 13.4 2.0 0.21 12.2 2.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Ets PF00178.22 KXX78273.1 - 0.097 13.1 0.1 0.27 11.7 0.1 1.7 1 0 0 1 1 1 0 Ets-domain FTO_CTD PF12934.7 KXX78273.1 - 0.13 12.1 0.4 0.24 11.1 0.4 1.4 1 0 0 1 1 1 0 FTO C-terminal domain TMCO5 PF14992.6 KXX78273.1 - 0.25 10.9 1.8 0.38 10.3 1.8 1.2 1 0 0 1 1 1 0 TMCO5 family SlyX PF04102.12 KXX78273.1 - 4.5 8.0 8.2 24 5.6 0.9 2.7 1 1 1 2 2 2 0 SlyX tRNA-synt_2b PF00587.25 KXX78274.1 - 4.2e-34 118.1 0.0 4.9e-32 111.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXX78274.1 - 2.5e-20 72.4 0.2 4.8e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KXX78274.1 - 1.4e-12 47.5 0.0 3.3e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KXX78274.1 - 1.4e-10 41.0 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain Transglut_core2 PF13369.6 KXX78275.1 - 8.6e-17 61.1 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KXX78275.1 - 2e-12 47.4 0.0 5.1e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.33 KXX78275.1 - 1.1e-07 31.5 0.8 3.6e-07 29.9 0.8 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX78275.1 - 1.1e-05 25.3 2.0 2.4e-05 24.1 2.0 1.7 1 0 0 1 1 1 1 F-box-like Peptidase_C12 PF01088.21 KXX78276.1 - 1.8e-60 204.3 0.0 2.7e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PrgU PF09627.10 KXX78276.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 PrgU-like protein CDP-OH_P_transf PF01066.21 KXX78277.1 - 2.6e-13 50.5 0.8 4.4e-13 49.8 0.1 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-C2H2 PF00096.26 KXX78278.1 - 1.1e-09 38.1 12.4 2.5e-05 24.5 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX78278.1 - 1.1e-08 35.1 13.3 9.3e-05 22.7 0.6 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX78278.1 - 2.7e-06 27.7 11.9 0.0014 19.3 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXX78278.1 - 2e-05 24.8 3.2 2e-05 24.8 1.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXX78278.1 - 0.00013 21.8 2.4 0.00013 21.8 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX78278.1 - 0.00083 19.6 1.8 0.00083 19.6 1.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXX78278.1 - 0.044 14.1 1.0 0.044 14.1 1.0 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PAP2 PF01569.21 KXX78278.1 - 0.072 12.9 0.9 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 PAP2 superfamily zf-C2HC_2 PF13913.6 KXX78278.1 - 0.14 12.1 4.7 3.2 7.7 0.4 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KXX78278.1 - 8.9 6.2 13.2 7.9 6.3 1.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type HAD PF12710.7 KXX78279.1 - 1.5e-07 32.0 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX78279.1 - 0.0023 18.2 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXX78279.1 - 0.0025 17.2 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase_3 PF08282.12 KXX78279.1 - 0.011 15.5 0.7 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXX78279.1 - 0.069 12.7 0.1 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 KXX78279.1 - 0.17 12.0 0.0 3.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TFIIF_beta_N PF17683.1 KXX78280.1 - 2e-34 119.2 0.6 3.6e-34 118.4 0.1 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KXX78280.1 - 5.5e-28 96.9 0.1 1e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 KXX78280.1 - 0.024 15.5 2.8 0.088 13.6 2.8 2.0 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain OGG_N PF07934.12 KXX78281.1 - 2.5e-34 117.9 0.0 4.8e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KXX78281.1 - 5.4e-17 62.2 0.0 1.1e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXX78281.1 - 0.00027 20.6 0.0 0.00079 19.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HECT_2 PF09814.9 KXX78282.1 - 7.5e-102 341.0 1.8 8.4e-102 340.8 1.8 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.7 KXX78282.1 - 0.064 13.3 0.7 17 5.5 0.1 2.7 2 0 0 2 2 2 0 Double zinc ribbon SF3b1 PF08920.10 KXX78283.1 - 1.1e-23 84.0 8.6 1.1e-23 84.0 8.6 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KXX78283.1 - 1.1e-11 45.0 2.3 0.082 13.4 0.0 7.3 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 KXX78283.1 - 1.2e-10 41.6 8.1 0.6 10.5 0.0 7.9 5 3 4 9 9 9 3 HEAT repeats HEAT PF02985.22 KXX78283.1 - 9.9e-10 37.8 5.6 0.75 10.2 0.0 8.8 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KXX78283.1 - 2.8e-05 24.6 0.3 1.5 9.5 0.0 5.2 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KXX78283.1 - 5.1e-05 23.2 0.9 0.0072 16.3 0.0 4.4 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 KXX78283.1 - 0.00025 20.8 0.7 0.9 9.2 0.0 4.2 4 1 1 5 5 5 2 NUC173 domain Adaptin_N PF01602.20 KXX78283.1 - 0.00054 18.6 0.1 0.13 10.8 0.0 3.0 2 2 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 KXX78283.1 - 0.0096 15.5 0.0 1.8 8.0 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal UNC45-central PF11701.8 KXX78283.1 - 0.02 14.8 0.0 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DRIM PF07539.12 KXX78283.1 - 0.021 13.1 0.2 4.7 5.4 0.0 3.7 2 1 2 4 4 3 0 Down-regulated in metastasis Rax2 PF12768.7 KXX78285.1 - 3.7e-73 245.5 0.0 4.9e-72 241.9 0.0 3.0 3 1 0 3 3 3 1 Cortical protein marker for cell polarity LapA_dom PF06305.11 KXX78285.1 - 0.063 13.1 0.3 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Kelch_3 PF13415.6 KXX78285.1 - 0.33 11.3 13.1 0.42 11.0 0.5 4.6 3 1 0 3 3 3 0 Galactose oxidase, central domain Syndecan PF01034.20 KXX78285.1 - 0.73 9.8 2.8 1.4 8.9 2.8 1.4 1 0 0 1 1 1 0 Syndecan domain SNase PF00565.17 KXX78286.1 - 1.2e-22 80.4 0.0 1.7e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Sel1 PF08238.12 KXX78288.1 - 5.7e-17 61.8 5.0 1.9e-05 25.2 0.0 4.4 5 0 0 5 5 5 3 Sel1 repeat P34-Arc PF04045.14 KXX78291.1 - 3.8e-105 350.9 0.1 4.6e-105 350.6 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Radical_SAM PF04055.21 KXX78291.1 - 0.15 12.5 0.6 0.94 9.8 0.2 2.1 1 1 1 2 2 2 0 Radical SAM superfamily WD40 PF00400.32 KXX78292.1 - 3.6e-47 157.4 21.9 1.6e-06 28.7 0.2 12.3 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 KXX78292.1 - 3e-18 66.1 0.4 1.3e-17 64.1 0.6 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXX78292.1 - 6.6e-16 58.4 10.4 0.13 12.6 0.1 9.2 5 2 5 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXX78292.1 - 0.00021 20.8 0.0 3.2 7.0 0.0 3.9 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 KXX78292.1 - 0.00022 20.1 0.1 0.31 9.6 0.0 4.4 4 1 0 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXX78292.1 - 0.00026 20.1 1.9 0.8 8.6 0.0 5.0 5 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KXX78292.1 - 0.0013 17.2 0.0 0.017 13.4 0.0 2.4 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KXX78292.1 - 0.0017 18.3 0.1 0.13 12.2 0.0 3.8 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KXX78292.1 - 0.0022 16.8 0.1 0.6 8.8 0.0 3.8 3 1 0 4 4 4 1 Nup133 N terminal like Hira PF07569.11 KXX78292.1 - 0.037 13.8 1.2 5.5 6.6 0.0 3.9 4 1 1 5 5 5 0 TUP1-like enhancer of split zf-CCCH PF00642.24 KXX78293.1 - 2.3e-11 43.3 25.7 2.2e-05 24.2 1.0 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXX78293.1 - 1.9e-08 34.1 30.1 0.00011 22.2 1.5 5.9 5 1 0 5 5 5 3 Zinc finger domain zf-CCCH_4 PF18044.1 KXX78293.1 - 1.3e-07 31.2 3.0 0.00031 20.4 0.5 4.6 6 0 0 6 6 6 2 CCCH-type zinc finger Torus PF16131.5 KXX78293.1 - 0.0011 19.6 21.1 0.26 12.0 1.6 4.6 1 1 3 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 KXX78293.1 - 0.013 15.7 15.7 0.038 14.2 1.3 3.4 1 1 2 3 3 3 0 Zinc-finger containing family FMO-like PF00743.19 KXX78294.1 - 1.2e-13 50.4 0.0 2.4e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXX78294.1 - 5.8e-10 38.8 0.0 3.7e-08 32.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXX78294.1 - 5.3e-07 29.8 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX78294.1 - 8.4e-07 28.5 0.0 6e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX78294.1 - 9e-06 25.1 0.0 4.3e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX78294.1 - 0.00039 20.4 0.3 0.00091 19.2 0.0 1.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXX78294.1 - 0.0016 17.7 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXX78294.1 - 0.027 13.2 0.1 0.042 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein LBR_tudor PF09465.10 KXX78294.1 - 0.031 14.1 0.1 0.078 12.8 0.1 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain FAD_binding_2 PF00890.24 KXX78294.1 - 0.033 13.3 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain RRM_1 PF00076.22 KXX78295.1 - 6.8e-26 89.9 0.3 4.3e-12 45.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXX78295.1 - 0.0058 16.5 0.1 0.58 10.1 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF4411 PF14367.6 KXX78295.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Ribosomal_S13_N PF08069.12 KXX78296.1 - 2.6e-30 104.3 0.1 4.4e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KXX78296.1 - 1.5e-15 57.2 0.2 2.3e-15 56.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KXX78296.1 - 0.032 14.1 0.1 0.083 12.8 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain HOIP-UBA PF16678.5 KXX78296.1 - 0.085 12.9 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 HOIP UBA domain pair VRR_NUC PF08774.11 KXX78297.1 - 2.2e-23 82.4 0.0 4.9e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain RPAP3_C PF13877.6 KXX78299.1 - 0.075 13.6 0.2 0.23 12.0 0.1 1.8 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 HET PF06985.11 KXX78300.1 - 2.3e-28 99.4 0.0 5.8e-28 98.1 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF1040 PF06288.13 KXX78301.1 - 0.44 11.0 1.1 0.88 10.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) Epimerase PF01370.21 KXX78302.1 - 5.6e-18 65.3 0.0 6.9e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX78302.1 - 3.5e-08 33.2 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXX78302.1 - 4.8e-06 25.9 0.0 0.016 14.4 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KXX78302.1 - 1.6e-05 24.0 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXX78302.1 - 5.8e-05 22.3 0.0 9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXX78302.1 - 0.00073 19.5 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_127 PF07944.12 KXX78303.1 - 3.4e-138 461.4 0.0 3.9e-138 461.2 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 WD40 PF00400.32 KXX78304.1 - 1.7e-35 120.4 27.6 7.9e-09 36.0 2.9 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.12 KXX78304.1 - 1.5e-25 90.1 0.0 2.9e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KXX78304.1 - 6.4e-15 55.2 2.6 1.6e-05 25.1 0.4 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX78304.1 - 1.6e-08 33.7 4.9 0.063 11.9 0.1 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXX78304.1 - 7.2e-05 22.2 9.8 0.64 9.3 0.1 4.2 1 1 3 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KXX78304.1 - 8e-05 21.7 0.8 3.3 6.6 0.0 3.8 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF676 PF05057.14 KXX78304.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 KXX78304.1 - 0.002 18.5 0.0 0.0064 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KXX78304.1 - 0.084 12.1 0.0 13 4.9 0.1 2.3 1 1 0 2 2 2 0 KAP family P-loop domain PGAP1 PF07819.13 KXX78304.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein HET PF06985.11 KXX78305.1 - 4.3e-21 75.8 0.0 9.9e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SET PF00856.28 KXX78306.1 - 4.8e-09 36.8 0.0 1.7e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 SET domain TPR_16 PF13432.6 KXX78306.1 - 0.31 11.7 0.1 0.31 11.7 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NYN PF01936.18 KXX78307.1 - 9.3e-32 110.5 0.0 1.6e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KXX78307.1 - 1.1e-13 50.8 0.0 2.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Helo_like_N PF17111.5 KXX78308.1 - 4.4e-05 22.9 1.2 6.7e-05 22.3 1.2 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF4503 PF14951.6 KXX78308.1 - 0.047 12.1 0.1 0.11 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) RTA1 PF04479.13 KXX78309.1 - 7.3e-54 182.5 8.8 7.3e-54 182.5 8.8 1.5 2 0 0 2 2 2 1 RTA1 like protein GH131_N PF18271.1 KXX78310.1 - 1e-64 218.7 0.0 1.3e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 KXX78310.1 - 8.9e-10 38.4 13.5 2.8e-09 36.8 13.5 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Esterase_phd PF10503.9 KXX78311.1 - 2.2e-26 92.7 0.2 2.9e-26 92.3 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXX78311.1 - 4.4e-12 45.9 0.5 6.1e-12 45.5 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXX78311.1 - 1.5e-05 24.8 0.1 2.3e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.28 KXX78311.1 - 3.1e-05 23.1 0.1 5.1e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 KXX78311.1 - 6.2e-05 22.8 0.1 7.6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXX78311.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 KXX78311.1 - 0.00026 20.3 0.4 0.00049 19.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Hydrolase_4 PF12146.8 KXX78311.1 - 0.00059 19.2 0.0 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KXX78311.1 - 0.00089 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KXX78311.1 - 0.0025 17.8 0.2 0.0038 17.2 0.2 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 KXX78311.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 KXX78311.1 - 0.018 14.6 0.3 0.028 14.0 0.3 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Eno-Rase_NADH_b PF12242.8 KXX78311.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase His_Phos_1 PF00300.22 KXX78312.1 - 4.3e-30 104.9 0.1 1.4e-28 99.9 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_43 PF04616.14 KXX78313.1 - 1.3e-46 159.2 2.8 1.6e-46 159.0 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_3 PF07859.13 KXX78314.1 - 6.8e-41 140.5 1.0 1.6e-40 139.2 1.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXX78314.1 - 0.012 14.5 0.3 0.05 12.4 0.3 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase AltA1 PF16541.5 KXX78316.1 - 1.6e-09 38.6 10.4 0.00099 20.0 0.8 3.5 3 0 0 3 3 3 3 Alternaria alternata allergen 1 Sulfotransfer_4 PF17784.1 KXX78317.1 - 1.5e-65 221.0 0.2 2.1e-65 220.5 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXX78317.1 - 6.5e-05 23.4 0.5 0.44 10.9 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family DNA_binding_1 PF01035.20 KXX78318.1 - 3.3e-22 78.4 0.0 5.1e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain 2OG-FeII_Oxy_3 PF13640.6 KXX78319.1 - 0.083 13.8 0.0 0.13 13.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KXX78320.1 - 2.1e-14 53.2 28.5 2.1e-14 53.2 28.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXX78320.1 - 6.2e-12 45.5 5.0 6.2e-12 45.5 5.0 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KXX78320.1 - 0.0042 16.0 5.4 0.0042 16.0 5.4 2.3 1 1 2 3 3 3 1 MFS_1 like family Na_Ca_ex PF01699.24 KXX78320.1 - 5.1 7.0 15.1 2 8.3 3.5 3.2 2 1 0 2 2 2 0 Sodium/calcium exchanger protein AcetylCoA_hydro PF02550.15 KXX78321.1 - 2.3e-48 164.8 0.0 3.4e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KXX78321.1 - 8.9e-39 132.9 0.0 1.3e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RasGEF PF00617.19 KXX78322.1 - 2.2e-52 177.8 0.1 4.7e-52 176.8 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXX78322.1 - 3.5e-16 59.3 0.1 1.5e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 KXX78322.1 - 7.2e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXX78322.1 - 0.00014 21.4 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Exo_endo_phos PF03372.23 KXX78323.1 - 0.0012 18.5 0.2 0.0026 17.3 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.17 KXX78323.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain AIM24 PF01987.17 KXX78324.1 - 4.8e-52 176.7 0.0 5.8e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Cutinase PF01083.22 KXX78325.1 - 3.4e-54 183.5 7.9 4.2e-54 183.2 7.9 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.18 KXX78325.1 - 1.5e-10 40.8 13.8 1.5e-10 40.8 13.8 4.0 5 1 0 5 5 5 1 Fungal cellulose binding domain PE-PPE PF08237.11 KXX78325.1 - 4.7e-06 26.3 0.2 6.5e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 KXX78325.1 - 0.00032 20.4 0.1 0.00042 20.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX78325.1 - 0.032 13.5 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Secretin_N PF03958.17 KXX78325.1 - 0.044 14.2 0.1 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain VirJ PF06057.11 KXX78325.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Toxin_7 PF05980.12 KXX78325.1 - 1.7 9.0 17.7 0.29 11.4 10.0 2.7 2 0 0 2 2 2 0 Toxin 7 ABC_membrane PF00664.23 KXX78326.1 - 5.3e-46 157.5 12.3 6.6e-46 157.2 12.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXX78326.1 - 1e-32 113.5 0.0 1.6e-31 109.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KXX78326.1 - 9.4e-06 26.1 0.0 2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KXX78326.1 - 2.8e-05 23.7 0.0 0.0091 15.4 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXX78326.1 - 0.00037 20.8 0.0 0.0046 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXX78326.1 - 0.00071 19.5 0.1 0.025 14.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 KXX78326.1 - 0.0031 17.5 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXX78326.1 - 0.0081 16.1 0.0 0.024 14.6 0.0 1.7 2 0 0 2 2 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KXX78326.1 - 0.013 15.5 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 KXX78326.1 - 0.014 15.8 0.0 0.14 12.6 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXX78326.1 - 0.017 14.7 0.0 0.086 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXX78326.1 - 0.023 14.0 0.0 0.095 12.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KXX78326.1 - 0.025 14.7 0.0 0.077 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXX78326.1 - 0.035 13.9 0.1 0.083 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KXX78326.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXX78326.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 KXX78326.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KXX78326.1 - 0.075 13.6 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KXX78326.1 - 0.079 12.7 0.1 0.9 9.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXX78326.1 - 0.086 12.6 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXX78326.1 - 0.098 12.6 0.1 0.82 9.5 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KXX78326.1 - 0.14 12.0 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 KXX78326.1 - 0.16 12.3 0.5 2.7 8.3 0.5 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KXX78326.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SPC25 PF06703.11 KXX78326.1 - 1.4 8.7 3.9 1.9 8.3 3.2 1.5 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CREPT PF16566.5 KXX78327.1 - 0.052 13.7 1.3 0.052 13.7 1.3 2.3 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3475 PF11961.8 KXX78327.1 - 0.28 11.3 2.4 0.39 10.8 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) DUF1482 PF07358.11 KXX78327.1 - 0.8 9.7 5.2 0.65 10.0 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1482) DUF3539 PF12058.8 KXX78327.1 - 1.9 8.7 10.9 0.22 11.7 1.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3539) NUDIX_4 PF14815.6 KXX78328.1 - 8.3e-19 67.6 0.0 1.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 KXX78328.1 - 6.4e-16 58.8 0.0 1.6e-15 57.4 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXX78328.1 - 6.6e-06 25.7 0.1 1.5e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif FeS PF04060.13 KXX78328.1 - 0.025 14.2 0.5 0.066 12.9 0.5 1.7 1 0 0 1 1 1 0 Putative Fe-S cluster Whib PF02467.16 KXX78328.1 - 0.12 13.0 0.5 0.39 11.3 0.1 2.1 2 0 0 2 2 2 0 Transcription factor WhiB ACPS PF01648.20 KXX78330.1 - 1e-10 41.7 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KXX78330.1 - 0.00012 22.1 0.2 0.54 10.4 0.0 2.6 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain PHP PF02811.19 KXX78331.1 - 4.9e-10 40.0 0.0 1.4e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 PHP domain AA_permease_2 PF13520.6 KXX78332.1 - 1e-55 189.3 44.6 1.3e-55 189.0 44.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX78332.1 - 1.3e-15 57.0 37.9 1.7e-15 56.6 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease PCDO_beta_N PF12391.8 KXX78333.1 - 0.15 11.7 0.8 0.42 10.3 0.1 2.0 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal DUF3433 PF11915.8 KXX78334.1 - 1.7e-08 34.8 2.0 3.2e-08 33.9 0.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3433) KorB PF08535.10 KXX78334.1 - 0.031 14.3 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 KorB domain Asp PF00026.23 KXX78335.1 - 3.7e-56 190.8 0.0 4.2e-55 187.4 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX78335.1 - 2e-10 41.2 0.2 1.1e-06 28.9 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal SDH_alpha PF03313.15 KXX78335.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain RseA_C PF03873.13 KXX78335.1 - 0.23 11.7 0.4 0.44 10.8 0.4 1.4 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain DHDPS PF00701.22 KXX78336.1 - 6.3e-31 107.2 0.0 8.4e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Kinesin PF00225.23 KXX78337.1 - 6.9e-78 261.9 0.0 9.9e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXX78337.1 - 6.2e-19 68.4 0.0 1.4e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding PBP1_TM PF14812.6 KXX78337.1 - 0.2 12.0 7.7 0.61 10.5 7.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAP2 PF01569.21 KXX78338.1 - 8.8e-24 83.8 7.8 2.2e-23 82.5 7.8 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KXX78338.1 - 7.3 7.2 8.6 1 9.9 1.3 3.0 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Cation_ATPase_C PF00689.21 KXX78339.1 - 1.3e-47 161.8 1.1 1.3e-47 161.8 1.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXX78339.1 - 1.3e-35 122.6 0.4 1.3e-35 122.6 0.4 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXX78339.1 - 4.5e-22 77.9 0.0 9.4e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX78339.1 - 2.1e-20 74.0 0.2 4.7e-20 72.8 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXX78339.1 - 1.9e-06 27.8 0.6 2.7e-05 24.0 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX78339.1 - 4.5e-06 26.3 0.2 2.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus LptF_LptG PF03739.14 KXX78339.1 - 0.045 12.6 3.3 0.056 12.3 1.6 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG FAD_binding_4 PF01565.23 KXX78340.1 - 2.4e-20 72.7 2.0 3.7e-20 72.1 2.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX78340.1 - 1e-11 44.7 0.0 2.8e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KXX78342.1 - 9.5e-17 61.1 0.3 3.7e-16 59.2 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXX78342.1 - 8.9e-10 38.8 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXX78342.1 - 5.9e-07 29.3 0.2 1.2e-05 25.0 0.0 2.3 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXX78342.1 - 0.00018 21.0 0.0 0.00041 19.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXX78342.1 - 0.0059 15.8 0.1 0.012 14.8 0.1 1.6 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KXX78342.1 - 0.024 13.8 0.2 0.024 13.8 0.2 1.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXX78342.1 - 0.072 13.2 0.2 0.15 12.1 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Turandot PF07240.11 KXX78342.1 - 0.11 12.5 0.8 0.33 11.0 0.1 2.1 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot RmlD_sub_bind PF04321.17 KXX78342.1 - 0.14 11.3 0.0 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans PF04082.18 KXX78343.1 - 7.4e-09 35.0 0.0 1.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain XFP_N PF09364.10 KXX78344.1 - 3.7e-148 493.2 0.0 5e-148 492.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KXX78344.1 - 3.8e-76 254.7 0.0 6.5e-76 254.0 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KXX78344.1 - 9.3e-76 253.8 0.0 1.5e-75 253.1 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 KXX78344.1 - 0.0043 16.9 0.1 0.025 14.4 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Hexapep PF00132.24 KXX78345.1 - 1.3e-07 31.0 9.7 0.0053 16.4 4.7 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXX78345.1 - 2.7e-06 27.0 9.7 0.0038 16.9 4.8 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KXX78345.1 - 0.0021 18.3 1.2 0.0034 17.6 1.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase DUF1996 PF09362.10 KXX78347.1 - 3.7e-81 272.5 1.3 3.7e-81 272.5 1.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Rick_17kDa_Anti PF05433.15 KXX78349.1 - 1.7 8.6 6.0 0.47 10.4 2.8 1.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain p450 PF00067.22 KXX78350.1 - 1.1e-46 159.5 0.0 1.4e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.12 KXX78351.1 - 2.3e-25 89.6 0.3 6.1e-25 88.2 0.2 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KXX78351.1 - 8.7e-06 25.8 0.0 9e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 Strictosidine synthase NHL PF01436.21 KXX78351.1 - 3.5e-05 23.6 3.0 0.0087 16.1 0.0 3.5 3 0 0 3 3 3 1 NHL repeat Arylesterase PF01731.20 KXX78351.1 - 0.00011 22.4 0.4 0.0036 17.5 0.0 2.9 3 0 0 3 3 3 1 Arylesterase SBBP PF06739.11 KXX78351.1 - 0.014 15.4 1.0 0.86 9.6 0.2 2.7 2 0 0 2 2 2 0 Beta-propeller repeat Glyco_hydro_61 PF03443.14 KXX78352.1 - 3.5e-54 183.9 0.0 4.7e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_S8 PF00082.22 KXX78354.1 - 1.2e-16 60.8 0.0 2.6e-16 59.7 0.0 1.5 1 1 0 1 1 1 1 Subtilase family HET PF06985.11 KXX78355.1 - 1.8e-29 103.0 0.0 3.3e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRTP PF01366.18 KXX78356.1 - 0.034 12.2 0.0 0.05 11.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ABM PF03992.16 KXX78356.1 - 0.28 11.3 2.3 27 4.9 0.0 3.2 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase AAA PF00004.29 KXX78357.1 - 8.8e-16 58.5 0.0 5.7e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX78357.1 - 0.0027 18.0 0.0 0.042 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX78357.1 - 0.007 16.8 0.0 0.026 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KXX78357.1 - 0.0079 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX78357.1 - 0.011 15.7 0.1 0.09 12.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXX78357.1 - 0.012 16.1 0.0 0.029 14.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 KXX78357.1 - 0.013 15.1 0.1 0.19 11.4 0.0 2.2 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) NB-ARC PF00931.22 KXX78357.1 - 0.082 12.1 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 KXX78357.1 - 0.15 12.5 0.2 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXX78357.1 - 0.18 11.2 0.1 0.42 10.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI adh_short PF00106.25 KXX78358.1 - 8.3e-44 149.4 1.6 1.1e-43 149.0 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX78358.1 - 2.2e-42 145.3 2.3 3.7e-42 144.5 2.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX78358.1 - 1.9e-07 31.2 5.0 1.2e-06 28.6 5.0 2.1 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXX78358.1 - 0.00048 19.6 0.0 0.00071 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KXX78358.1 - 0.0033 17.4 0.1 0.0071 16.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KXX78358.1 - 0.0054 16.8 0.1 0.01 15.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KXX78358.1 - 0.0082 15.3 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1729 PF08354.10 KXX78358.1 - 0.014 14.3 0.1 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) NAD_binding_7 PF13241.6 KXX78358.1 - 0.032 14.7 0.6 0.17 12.3 0.3 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Epimerase PF01370.21 KXX78358.1 - 0.065 12.7 1.9 0.22 10.9 1.9 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX78358.1 - 0.1 12.0 1.6 0.2 11.0 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Chitin_synth_2 PF03142.15 KXX78359.1 - 1.7e-292 970.8 0.1 2.4e-292 970.2 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXX78359.1 - 5.8e-14 52.5 5.9 2.5e-13 50.4 5.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXX78359.1 - 3e-10 40.4 0.1 5.5e-09 36.3 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXX78359.1 - 0.0018 17.8 0.0 0.0094 15.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXX78359.1 - 0.033 14.0 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 RNB PF00773.19 KXX78360.1 - 1.3e-57 195.6 0.0 5.4e-57 193.6 0.0 2.0 2 1 0 2 2 2 1 RNB domain Prenyltransf PF01255.19 KXX78362.1 - 5.9e-05 22.7 0.0 0.0064 16.0 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase SWIRM PF04433.17 KXX78363.1 - 2.6e-14 53.3 0.2 1.7e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 SWIRM domain F-box-like PF12937.7 KXX78364.1 - 2e-08 34.0 0.5 4e-08 33.0 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX78364.1 - 4.1e-06 26.5 1.2 7.6e-06 25.7 1.2 1.4 1 0 0 1 1 1 1 F-box domain Gpr1_Fun34_YaaH PF01184.19 KXX78365.1 - 8.9e-26 90.8 23.1 8.2e-25 87.6 23.1 1.9 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family Met_10 PF02475.16 KXX78366.1 - 8.1e-76 254.2 0.0 1.1e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Gly_acyl_tr_N PF06021.11 KXX78366.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Sec10 PF07393.11 KXX78367.1 - 2e-228 760.4 4.9 2.5e-228 760.1 4.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Ku_PK_bind PF08785.11 KXX78367.1 - 0.015 15.5 0.1 0.75 10.0 0.0 3.0 2 0 0 2 2 2 0 Ku C terminal domain like K_channel_TID PF07941.11 KXX78367.1 - 0.75 10.3 12.2 0.11 13.0 6.8 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Phage_Mu_Gam PF07352.12 KXX78367.1 - 1.9 8.4 6.0 1.8 8.4 0.5 3.2 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein DUF2415 PF10313.9 KXX78368.1 - 0.015 15.2 0.0 0.051 13.5 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KXX78368.1 - 0.63 11.0 2.4 6.7 7.8 0.2 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat SDA1 PF05285.12 KXX78368.1 - 5.1 6.4 21.8 0.12 11.8 14.7 1.8 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 KXX78368.1 - 7.1 5.8 21.5 0.16 11.3 15.0 1.4 2 0 0 2 2 2 0 BUD22 SKG6 PF08693.10 KXX78369.1 - 0.016 14.6 2.5 0.044 13.2 2.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Granulin PF00396.18 KXX78369.1 - 0.15 12.4 5.1 0.36 11.2 1.7 2.6 2 0 0 2 2 2 0 Granulin LURAP PF14854.6 KXX78369.1 - 0.24 11.3 1.4 0.37 10.7 1.4 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF347 PF03988.12 KXX78369.1 - 1.4 9.2 5.0 0.19 11.9 0.6 1.9 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DSS1_SEM1 PF05160.13 KXX78371.1 - 1.8e-23 82.3 18.0 2.8e-23 81.7 18.0 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family NDUF_B8 PF05821.11 KXX78371.1 - 0.23 11.3 2.5 0.24 11.3 2.5 1.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cwf_Cwc_15 PF04889.12 KXX78371.1 - 0.26 11.0 15.1 0.28 10.9 15.1 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3808 PF10300.9 KXX78372.1 - 2.3e-127 425.7 0.0 2.7e-127 425.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) PGK PF00162.19 KXX78373.1 - 8.3e-150 498.9 1.2 9.4e-150 498.8 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 KXX78373.1 - 0.00044 20.2 0.0 0.11 12.5 0.0 3.0 3 1 0 3 3 3 1 PA domain DUF3530 PF12048.8 KXX78373.1 - 0.039 13.4 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) FIVAR PF07554.13 KXX78373.1 - 0.046 14.5 0.7 7.7 7.4 0.0 3.5 4 0 0 4 4 4 0 FIVAR domain DUF4434 PF14488.6 KXX78373.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Mpv17_PMP22 PF04117.12 KXX78374.1 - 1.8e-21 76.1 0.1 1.8e-21 76.1 0.1 2.2 3 0 0 3 3 3 1 Mpv17 / PMP22 family DUF746 PF05344.11 KXX78374.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DLH PF01738.18 KXX78376.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family FA_hydroxylase PF04116.13 KXX78378.1 - 2.9e-07 30.9 5.9 2.9e-07 30.9 5.9 2.9 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily FSH1 PF03959.13 KXX78379.1 - 3.6e-23 82.3 0.0 5.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXX78379.1 - 0.01 15.6 0.5 0.22 11.3 0.3 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Glyco_transf_15 PF01793.16 KXX78381.1 - 1.5e-92 310.4 4.8 3.3e-92 309.2 4.8 1.5 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SAM_adeno_trans PF01887.16 KXX78383.1 - 0.052 13.0 0.0 0.53 9.7 0.0 1.9 1 1 1 2 2 2 0 S-adenosyl-l-methionine hydroxide adenosyltransferase AA_permease_2 PF13520.6 KXX78384.1 - 8.9e-67 225.8 46.1 1.1e-66 225.4 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX78384.1 - 1.1e-17 63.8 41.8 1.5e-17 63.4 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 KXX78385.1 - 4.4e-23 81.8 0.5 1.1e-19 70.7 0.9 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX78385.1 - 9.5e-17 61.3 0.7 5e-12 45.9 1.4 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX78385.1 - 2.5e-10 40.6 1.0 5.4e-10 39.5 1.0 1.5 1 0 0 1 1 1 1 KR domain TraX PF05857.11 KXX78385.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 TraX protein GMC_oxred_N PF00732.19 KXX78386.1 - 2.3e-51 174.9 0.0 3.2e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX78386.1 - 2.3e-27 96.3 0.1 4.2e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXX78386.1 - 0.00037 20.7 0.2 0.0011 19.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX78386.1 - 0.00045 19.4 0.4 0.0011 18.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX78386.1 - 0.0043 16.3 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX78386.1 - 0.0049 16.0 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXX78386.1 - 0.0057 16.3 0.1 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXX78386.1 - 0.0064 15.8 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 KXX78386.1 - 0.021 15.1 0.2 0.052 13.8 0.2 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KXX78386.1 - 0.038 13.2 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX78386.1 - 0.044 12.5 0.0 0.33 9.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KXX78386.1 - 0.059 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXX78386.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SpoV PF08183.11 KXX78386.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Stage V sporulation protein family AA_permease PF00324.21 KXX78387.1 - 8.3e-124 413.8 42.1 9.8e-124 413.5 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX78387.1 - 2.8e-31 108.8 46.1 3.8e-31 108.4 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_23 PF13489.6 KXX78388.1 - 8.1e-19 68.1 0.0 1.1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX78388.1 - 2e-16 60.4 0.1 5.6e-15 55.8 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX78388.1 - 5.2e-16 59.1 0.0 2.7e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXX78388.1 - 9.5e-14 51.9 0.0 1.1e-12 48.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX78388.1 - 1.2e-12 47.9 0.0 2e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXX78388.1 - 9e-05 21.9 0.1 0.1 11.9 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX78388.1 - 0.00064 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KXX78388.1 - 0.0013 17.9 0.0 0.052 12.6 0.0 2.1 2 0 0 2 2 2 1 DREV methyltransferase PrmA PF06325.13 KXX78388.1 - 0.0079 15.6 0.0 0.065 12.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KXX78388.1 - 0.011 15.4 0.0 0.6 9.7 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) RrnaAD PF00398.20 KXX78388.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 KXX78388.1 - 0.018 14.5 0.0 0.038 13.4 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 KXX78388.1 - 0.033 13.2 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_16 PF10294.9 KXX78388.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase AltA1 PF16541.5 KXX78389.1 - 0.00054 20.8 7.7 0.0049 17.7 1.5 2.8 2 2 0 2 2 2 2 Alternaria alternata allergen 1 DUF1996 PF09362.10 KXX78390.1 - 1.2e-82 277.4 0.2 1.5e-82 277.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Egh16-like PF11327.8 KXX78392.1 - 3e-64 216.8 7.5 3.8e-64 216.5 7.5 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Loricrin PF15847.5 KXX78392.1 - 0.15 11.1 17.7 0.026 13.6 13.7 1.6 2 0 0 2 2 2 0 Major keratinocyte cell envelope protein Glyco_hydro_16 PF00722.21 KXX78393.1 - 9.2e-15 54.6 0.1 3.2e-14 52.8 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXX78393.1 - 3.6e-06 25.7 8.0 0.0017 16.9 0.6 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KXX78393.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) CVNH PF08881.10 KXX78395.1 - 7.5e-33 113.2 0.0 1.5e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 CVNH domain LysM PF01476.20 KXX78395.1 - 5.2e-15 55.2 0.0 9e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.15 KXX78395.1 - 5.8e-07 29.3 24.0 5.8e-07 29.3 24.0 2.1 2 0 0 2 2 1 1 Glycine zipper 2TM domain DUF2076 PF09849.9 KXX78395.1 - 7.1e-05 23.0 12.8 0.00013 22.1 12.8 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF533 PF04391.12 KXX78395.1 - 0.04 13.5 0.3 0.04 13.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DUF2828 PF11443.8 KXX78395.1 - 0.12 10.5 6.5 0.16 10.1 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TraT PF05818.12 KXX78395.1 - 0.12 12.1 0.2 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein RR_TM4-6 PF06459.12 KXX78395.1 - 0.13 12.1 9.6 0.19 11.5 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 G0-G1_switch_2 PF15103.6 KXX78395.1 - 0.13 12.7 4.0 0.27 11.7 4.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2151 PF10221.9 KXX78395.1 - 0.44 9.1 3.7 0.52 8.8 3.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 KXX78395.1 - 0.78 8.0 15.3 1.1 7.5 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4569 PF15133.6 KXX78395.1 - 0.84 9.3 3.1 1.2 8.8 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4407 PF14362.6 KXX78395.1 - 0.98 8.7 2.3 1.2 8.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 KXX78395.1 - 2.3 7.3 4.5 3.3 6.8 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ATPase_gene1 PF09527.10 KXX78395.1 - 2.5 8.3 6.4 4.5 7.5 6.4 1.4 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Presenilin PF01080.17 KXX78395.1 - 2.9 6.5 8.8 4.1 6.1 8.8 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 KXX78395.1 - 4.3 7.1 7.0 7.6 6.2 7.0 1.4 1 0 0 1 1 1 0 AAA domain Merozoite_SPAM PF07133.11 KXX78395.1 - 4.5 7.2 20.2 6.6 6.7 20.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Sec62 PF03839.16 KXX78395.1 - 6.7 6.2 7.1 9.5 5.7 7.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 HET PF06985.11 KXX78396.1 - 1.1e-28 100.4 0.0 2.8e-28 99.1 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DEAD PF00270.29 KXX78398.1 - 2.5e-46 157.7 0.0 5.2e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX78398.1 - 1.3e-23 83.4 0.0 5.2e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXX78398.1 - 6e-17 61.6 0.0 2.1e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXX78398.1 - 1.7e-07 31.4 0.0 7.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXX78398.1 - 0.012 14.8 0.0 0.038 13.2 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Sad1_UNC PF07738.13 KXX78399.1 - 3e-09 37.0 0.0 0.0012 18.8 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF1216 PF06746.11 KXX78399.1 - 0.15 12.0 2.3 22 5.1 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) Epimerase PF01370.21 KXX78400.1 - 1e-48 165.9 0.0 1.3e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX78400.1 - 9.9e-47 159.9 0.0 1.6e-46 159.2 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXX78400.1 - 1.6e-15 56.9 0.0 6.3e-15 54.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXX78400.1 - 2.6e-13 49.8 0.2 2.1e-11 43.5 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXX78400.1 - 5.5e-13 48.7 0.0 8e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXX78400.1 - 1.2e-08 34.7 0.1 1.9e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KXX78400.1 - 1.5e-06 27.6 0.0 8.3e-05 21.9 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KXX78400.1 - 2.2e-06 27.7 0.0 4.1e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXX78400.1 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KXX78400.1 - 0.0026 17.3 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 KXX78400.1 - 0.01 15.4 0.2 0.018 14.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 KXX78400.1 - 0.015 14.9 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family ADH_zinc_N PF00107.26 KXX78401.1 - 1.9e-24 86.1 0.0 2.7e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX78401.1 - 4.4e-19 69.8 0.0 9.8e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX78401.1 - 4.3e-07 29.8 0.0 1.6e-06 27.9 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXX78401.1 - 9.7e-05 22.2 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 KXX78401.1 - 0.0089 15.5 0.2 0.014 14.8 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase XRN1_D2_D3 PF18334.1 KXX78401.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D2/D3 domain Radical_SAM PF04055.21 KXX78402.1 - 2.7e-19 70.2 0.1 5.2e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXX78402.1 - 8.8e-06 26.0 0.1 1.5e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXX78402.1 - 1.4e-05 25.2 0.2 3.4e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain ADK PF00406.22 KXX78403.1 - 2.4e-17 63.4 0.0 3.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXX78403.1 - 2.3e-16 60.5 0.0 3.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXX78403.1 - 2.2e-05 24.6 0.0 4.3e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXX78403.1 - 7.7e-05 23.2 0.0 0.00016 22.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain DIE2_ALG10 PF04922.12 KXX78404.1 - 6.4e-123 410.9 4.2 8.2e-123 410.6 4.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family QCR10 PF09796.9 KXX78404.1 - 2.3e-16 59.6 7.6 4.4e-11 42.7 0.5 3.5 3 0 0 3 3 3 2 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Chitin_bind_1 PF00187.19 KXX78408.1 - 1.4e-07 31.8 13.2 1.4e-07 31.8 13.2 2.8 2 1 1 3 3 3 2 Chitin recognition protein Conotoxin PF02950.17 KXX78408.1 - 3.6 8.7 9.4 1.2 10.2 0.4 2.3 1 1 1 2 2 2 0 Conotoxin Phytase PF02333.15 KXX78409.1 - 2.7e-63 214.2 0.0 7.9e-62 209.4 0.0 2.1 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 KXX78409.1 - 3.1e-07 30.6 33.8 0.00019 21.7 9.2 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 KXX78409.1 - 0.14 12.5 23.5 0.24 11.7 4.6 2.5 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_11 PF00457.17 KXX78410.1 - 5.3e-73 244.4 14.5 6.1e-73 244.2 14.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 FMO-like PF00743.19 KXX78411.1 - 3.5e-14 52.1 0.0 4.1e-13 48.6 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXX78411.1 - 1.3e-13 50.9 0.0 4.1e-12 46.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX78411.1 - 8.8e-11 41.6 0.0 9.8e-10 38.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXX78411.1 - 1.3e-07 31.1 0.1 4.4e-06 26.1 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXX78411.1 - 1.1e-06 28.7 0.8 8.5e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX78411.1 - 0.00011 21.9 3.0 0.00037 20.2 2.7 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX78411.1 - 0.00019 21.9 2.3 0.073 13.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXX78411.1 - 0.00066 19.0 0.3 0.092 12.0 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KXX78411.1 - 0.0027 17.8 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXX78411.1 - 0.0029 17.5 0.1 0.0073 16.2 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXX78411.1 - 0.0058 16.6 1.8 0.13 12.3 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXX78411.1 - 0.039 13.3 0.1 0.069 12.5 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX78411.1 - 0.088 11.9 3.7 0.065 12.3 0.7 1.9 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KXX78411.1 - 0.1 11.3 1.9 0.25 10.0 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KXX78411.1 - 1.1 8.2 3.6 0.44 9.6 0.5 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A EMP70 PF02990.16 KXX78413.1 - 6.5e-208 691.6 7.0 9.2e-208 691.1 7.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3920 PF13058.6 KXX78413.1 - 0.044 14.0 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Sas10_Utp3 PF04000.15 KXX78414.1 - 5.1e-18 65.5 2.3 1.1e-17 64.4 2.3 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Transp_cyt_pur PF02133.15 KXX78415.1 - 1.3e-148 495.5 35.0 1.5e-148 495.3 35.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Med4 PF10018.9 KXX78416.1 - 3.6e-55 186.7 11.1 6.1e-55 185.9 11.1 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4763 PF15960.5 KXX78416.1 - 0.012 15.0 0.5 0.012 15.0 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF1682 PF07946.14 KXX78416.1 - 0.023 13.9 5.5 0.043 13.0 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) UDPG_MGDP_dh_C PF03720.15 KXX78416.1 - 0.027 14.9 0.7 0.055 13.9 0.2 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF572 PF04502.13 KXX78416.1 - 0.48 10.0 8.4 0.19 11.3 2.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4407 PF14362.6 KXX78416.1 - 1.9 7.8 13.0 0.37 10.1 5.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ARGLU PF15346.6 KXX78416.1 - 2.8 7.8 27.9 0.21 11.4 20.9 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 SART-1 PF03343.13 KXX78416.1 - 3.3 6.1 14.5 4.9 5.6 14.5 1.3 1 1 0 1 1 1 0 SART-1 family TFIIA PF03153.13 KXX78416.1 - 3.5 7.5 19.0 7.9 6.4 19.1 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_13 PF13166.6 KXX78416.1 - 8 5.0 6.7 1.9 7.0 0.3 2.0 2 0 0 2 2 2 0 AAA domain Helicase_C PF00271.31 KXX78417.1 - 4.5e-11 43.1 0.0 8.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXX78417.1 - 0.0031 16.8 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2373 PF10180.9 KXX78418.1 - 0.0066 16.3 0.1 0.026 14.4 0.0 1.9 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) NMD3 PF04981.13 KXX78418.1 - 0.01 15.3 0.3 0.02 14.4 0.3 1.5 1 0 0 1 1 1 0 NMD3 family Rsa3 PF14615.6 KXX78418.1 - 0.022 14.3 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 Ribosome-assembly protein 3 DZR PF12773.7 KXX78418.1 - 0.13 12.3 1.7 8.5 6.5 0.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon Ank_2 PF12796.7 KXX78419.1 - 5e-32 110.3 12.8 2.2e-05 24.9 0.0 13.8 12 2 2 14 14 14 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX78419.1 - 8.9e-17 59.5 11.3 0.23 12.2 0.0 15.9 17 0 0 17 17 17 1 Ankyrin repeat Ank_4 PF13637.6 KXX78419.1 - 1.3e-14 54.3 14.2 0.027 15.1 0.0 13.7 12 5 4 16 16 16 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX78419.1 - 2.1e-09 37.5 9.6 0.0003 21.0 0.0 9.1 9 2 1 10 10 10 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX78419.1 - 1.7e-07 31.3 18.6 0.031 14.7 0.0 11.6 15 0 0 15 15 15 1 Ankyrin repeat DUF4761 PF15958.5 KXX78419.1 - 0.035 14.2 0.1 0.09 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Acetyltransf_9 PF13527.7 KXX78421.1 - 0.00024 21.2 0.0 0.00049 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX78421.1 - 0.0015 18.7 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX78421.1 - 0.037 14.0 0.0 0.087 12.8 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2264 PF10022.9 KXX78422.1 - 9e-135 449.3 0.2 1.2e-134 448.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FH2 PF02181.23 KXX78423.1 - 1.1e-83 281.5 5.7 1.1e-83 281.5 5.7 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KXX78423.1 - 1.7e-64 216.8 0.0 5.6e-64 215.2 0.0 2.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KXX78423.1 - 9.7e-54 181.9 4.7 2.1e-53 180.9 1.8 2.9 2 1 1 3 3 3 1 Diaphanous FH3 Domain Lysine_decarbox PF03641.14 KXX78425.1 - 1.9e-29 102.5 0.0 2.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXX78425.1 - 3.4e-05 23.5 2.4 0.00031 20.3 2.5 2.1 1 1 0 1 1 1 1 SLOG cluster4 family Glt_symporter PF03616.14 KXX78425.1 - 0.041 12.6 2.4 1.3 7.7 0.3 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter LSDAT_prok PF18171.1 KXX78425.1 - 0.11 11.8 0.4 0.51 9.5 0.1 2.1 1 1 1 2 2 2 0 SLOG in TRPM, prokaryote Proteasome PF00227.26 KXX78426.1 - 2e-51 174.2 0.1 2.5e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXX78426.1 - 2.3e-11 43.2 0.2 3.6e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SNRNP27 PF08648.12 KXX78427.1 - 5.2e-28 96.9 0.7 5.2e-28 96.9 0.7 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Elong_Iki1 PF10483.9 KXX78428.1 - 1.6e-77 260.9 0.0 2.2e-76 257.2 0.0 1.9 1 1 0 1 1 1 1 Elongator subunit Iki1 RAMP4 PF06624.12 KXX78429.1 - 1.6e-23 82.5 0.1 1.8e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SMAP PF15477.6 KXX78430.1 - 1.6e-11 45.0 3.1 1.6e-11 45.0 3.1 4.4 2 1 0 2 2 2 1 Small acidic protein family Anti-TRAP PF15777.5 KXX78431.1 - 0.1 12.6 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein CLPTM1 PF05602.12 KXX78432.1 - 1.9e-157 524.7 0.0 2.3e-157 524.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1772 PF08592.11 KXX78432.1 - 0.73 10.1 3.3 11 6.4 1.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) ASXH PF13919.6 KXX78433.1 - 3.4e-36 124.3 0.2 7e-36 123.3 0.2 1.5 1 0 0 1 1 1 1 Asx homology domain YL1_C PF08265.11 KXX78433.1 - 0.071 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Longin PF13774.6 KXX78434.1 - 3.7e-24 84.6 0.2 6.7e-24 83.7 0.1 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXX78434.1 - 3e-15 55.8 0.0 5.4e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF5435 PF17503.2 KXX78434.1 - 0.037 13.7 0.2 0.066 12.9 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5435) DUF334 PF03904.13 KXX78434.1 - 0.1 12.2 2.1 8.3 5.9 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF334) DUF1664 PF07889.12 KXX78434.1 - 0.83 9.7 5.8 0.4 10.7 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sensor PF13796.6 KXX78435.1 - 0.026 14.6 0.7 0.041 13.9 0.7 1.2 1 0 0 1 1 1 0 Putative sensor SPC12 PF06645.13 KXX78435.1 - 0.064 13.4 0.7 0.091 12.9 0.7 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PPP5 PF08321.12 KXX78436.1 - 3.6e-33 113.7 0.4 1.5e-32 111.7 0.1 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KXX78436.1 - 1.7e-30 107.0 0.1 2.7e-30 106.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KXX78436.1 - 4.2e-19 67.5 1.8 1.4e-05 24.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX78436.1 - 2e-15 55.5 1.0 0.00097 19.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXX78436.1 - 1.9e-08 33.8 1.1 0.00091 18.9 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 KXX78436.1 - 6.4e-07 29.3 3.7 0.0026 18.0 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXX78436.1 - 6.8e-07 29.0 0.3 0.084 13.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXX78436.1 - 4.1e-05 23.6 0.0 0.075 13.2 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX78436.1 - 0.00045 20.7 0.0 2.9 8.5 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX78436.1 - 0.0014 19.3 0.0 0.67 10.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX78436.1 - 0.0016 19.0 0.0 0.53 11.0 0.0 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXX78436.1 - 0.0046 16.2 0.1 0.16 11.1 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX78436.1 - 0.13 12.5 0.6 0.22 11.8 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXX78436.1 - 0.15 12.8 1.2 0.67 10.7 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat GST_N PF02798.20 KXX78438.1 - 1.4e-14 54.2 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX78438.1 - 5.6e-12 45.8 0.0 8.2e-11 42.0 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXX78438.1 - 1.2e-11 44.8 0.0 2.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXX78438.1 - 3.1e-11 43.3 0.0 1.8e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXX78438.1 - 1.5e-09 37.7 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX78438.1 - 7.3e-09 35.7 0.0 1.7e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 KXX78438.1 - 0.085 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NmrA PF05368.13 KXX78439.1 - 6.4e-12 45.5 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX78439.1 - 2.1e-05 24.5 0.1 4.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans_2 PF11951.8 KXX78439.1 - 0.0038 16.1 0.6 0.0054 15.6 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Epimerase PF01370.21 KXX78439.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX78439.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thioesterase PF00975.20 KXX78440.1 - 3.9e-18 66.4 0.1 9.2e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 Thioesterase domain AMP-binding PF00501.28 KXX78440.1 - 3.1e-11 42.5 0.4 4.8e-08 32.0 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme DLH PF01738.18 KXX78440.1 - 0.072 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family TB2_DP1_HVA22 PF03134.19 KXX78441.1 - 8e-29 99.4 8.8 1.3e-28 98.7 8.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bestrophin PF01062.21 KXX78441.1 - 0.03 13.7 0.5 0.042 13.2 0.5 1.3 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Phage_holin_3_6 PF07332.11 KXX78441.1 - 0.42 10.7 2.5 0.71 9.9 2.5 1.5 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RFX_DNA_binding PF02257.15 KXX78442.1 - 4.4e-28 97.7 0.1 9.7e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Hydrolase_4 PF12146.8 KXX78443.1 - 7.6e-49 166.1 0.0 9.1e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX78443.1 - 6.1e-13 49.0 0.0 8e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX78443.1 - 9.2e-13 49.3 2.1 1.1e-12 49.0 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXX78443.1 - 0.081 12.8 0.2 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) PGAP1 PF07819.13 KXX78443.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Cation_efflux PF01545.21 KXX78444.1 - 1.7e-12 47.5 2.7 2.3e-12 47.0 2.7 1.2 1 0 0 1 1 1 1 Cation efflux family DUF4824 PF16106.5 KXX78444.1 - 0.088 12.1 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) EspB PF05802.11 KXX78444.1 - 0.26 11.2 0.1 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Enterobacterial EspB protein 7TM_GPCR_Srsx PF10320.9 KXX78446.1 - 0.26 10.6 0.9 0.32 10.3 0.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Chorismate_bind PF00425.18 KXX78447.1 - 4.6e-65 219.8 0.2 1e-36 126.8 0.0 3.1 2 1 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 KXX78447.1 - 2e-21 76.6 0.0 1.3e-13 51.2 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KXX78447.1 - 2.7e-12 47.1 0.0 5.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KXX78447.1 - 1.9e-05 24.6 1.0 0.0074 16.1 0.1 2.4 2 0 0 2 2 2 2 Peptidase C26 Vps55 PF04133.14 KXX78448.1 - 6.2e-44 148.7 10.0 7e-44 148.5 10.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 adh_short PF00106.25 KXX78449.1 - 9.8e-20 70.8 0.0 2.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX78449.1 - 2.3e-16 60.1 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TRAPPC9-Trs120 PF08626.11 KXX78450.1 - 0 1379.4 0.0 0 1379.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TfuA PF07812.12 KXX78451.1 - 9.3e-16 57.6 0.0 1.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 TfuA-like protein CHAD PF05235.14 KXX78451.1 - 0.18 11.7 0.2 0.26 11.2 0.2 1.1 1 0 0 1 1 1 0 CHAD domain HET PF06985.11 KXX78452.1 - 1.4e-22 80.7 0.0 2.3e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KXX78453.1 - 1.6e-12 47.0 24.5 1e-06 28.0 5.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX78453.1 - 0.00016 20.2 1.1 0.00024 19.7 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX78453.1 - 0.0011 17.9 4.3 0.0011 17.9 4.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXX78453.1 - 0.65 8.2 6.3 0.64 8.2 3.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GST_N PF02798.20 KXX78454.1 - 1.8e-11 44.2 0.0 4.1e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX78454.1 - 9.3e-09 35.5 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXX78454.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX78454.1 - 1.6e-08 34.6 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX78454.1 - 6e-08 33.0 0.0 1.7e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX78454.1 - 3.6e-07 30.1 0.0 6.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mid1 PF12929.7 KXX78456.1 - 7.8e-156 519.5 0.1 9.1e-156 519.3 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KXX78456.1 - 8.5e-06 26.4 3.7 0.00042 20.9 1.0 2.5 2 0 0 2 2 2 2 Fz domain Fungal_trans_2 PF11951.8 KXX78457.1 - 2.4e-47 161.6 0.1 2.1e-28 99.2 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX78457.1 - 9.1e-07 28.9 6.6 1.9e-06 27.9 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S13 PF00416.22 KXX78458.1 - 4.1e-16 59.6 0.2 9.5e-14 51.9 0.2 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.21 KXX78459.1 - 5.1e-99 331.4 0.0 6e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) bZIP_2 PF07716.15 KXX78460.1 - 2.2e-07 30.8 14.6 5.2e-07 29.6 14.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXX78460.1 - 0.0001 22.3 13.9 0.00018 21.5 13.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXX78460.1 - 0.33 11.5 13.9 0.11 13.0 10.9 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Snf7 PF03357.21 KXX78461.1 - 0.0033 17.0 25.0 0.0033 17.0 25.0 1.5 1 1 0 1 1 1 1 Snf7 DltD PF04914.12 KXX78461.1 - 0.59 9.5 14.0 0.85 8.9 14.0 1.1 1 0 0 1 1 1 0 DltD protein Bud13 PF09736.9 KXX78461.1 - 7.1 7.0 20.9 5.7 7.3 1.6 2.1 1 1 1 2 2 2 0 Pre-mRNA-splicing factor of RES complex GST_N_3 PF13417.6 KXX78462.1 - 2.3e-15 56.7 0.0 6.9e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX78462.1 - 1.5e-14 54.1 0.0 2.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXX78462.1 - 6.2e-14 52.1 0.0 1.9e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KXX78462.1 - 5.1e-05 23.4 0.0 9.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 KXX78462.1 - 0.0049 16.9 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX78462.1 - 0.048 13.9 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX78462.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MMR_HSR1 PF01926.23 KXX78463.1 - 2.8e-06 27.4 0.0 1.6e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KXX78463.1 - 8.6e-05 22.2 0.0 0.00029 20.5 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXX78463.1 - 0.00048 20.1 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Septin PF00735.18 KXX78463.1 - 0.00083 18.7 0.1 0.0059 15.9 0.0 2.5 2 1 0 2 2 2 1 Septin FtsK_SpoIIIE PF01580.18 KXX78463.1 - 0.0058 16.0 0.0 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KXX78463.1 - 0.014 15.8 0.2 0.11 12.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_7 PF12775.7 KXX78463.1 - 0.016 14.7 0.0 0.047 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KXX78463.1 - 0.017 15.6 1.9 0.049 14.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KXX78463.1 - 0.019 15.5 0.2 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AIG1 PF04548.16 KXX78463.1 - 0.031 13.6 0.7 2.5 7.4 0.1 2.7 3 0 0 3 3 3 0 AIG1 family IIGP PF05049.13 KXX78463.1 - 0.033 13.2 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) CLP1_P PF16575.5 KXX78463.1 - 0.042 13.6 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Dynamin_N PF00350.23 KXX78463.1 - 0.048 13.7 0.9 7 6.7 0.1 3.1 3 0 0 3 3 3 0 Dynamin family Sigma54_activat PF00158.26 KXX78463.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KXX78463.1 - 0.074 12.1 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KXX78463.1 - 0.097 12.7 1.9 0.49 10.5 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_22 PF13401.6 KXX78463.1 - 0.11 12.7 0.0 0.7 10.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KXX78463.1 - 0.15 12.5 0.0 0.59 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KXX78463.1 - 0.15 12.3 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KXX78463.1 - 0.16 11.7 0.0 0.47 10.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pex16 PF08610.10 KXX78464.1 - 4.4e-136 453.3 0.5 5.1e-136 453.1 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SET PF00856.28 KXX78465.1 - 2.6e-13 50.7 0.0 1.1e-12 48.6 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF892 PF05974.12 KXX78465.1 - 0.18 11.9 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Nop16 PF09420.10 KXX78466.1 - 2e-64 217.5 13.5 2.3e-64 217.3 13.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 TerB_C PF15615.6 KXX78466.1 - 0.0059 16.9 4.0 0.011 16.1 4.0 1.4 1 0 0 1 1 1 1 TerB-C domain RhoGAP PF00620.27 KXX78467.1 - 1.5e-14 54.1 0.1 1.7e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KXX78467.1 - 3.5e-11 43.0 0.0 7.5e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KXX78467.1 - 5.5e-10 39.4 0.1 1.1e-08 35.2 0.0 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5343 PF17278.2 KXX78467.1 - 0.044 13.9 0.3 0.14 12.3 0.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5343) BAR PF03114.18 KXX78467.1 - 0.36 10.4 7.1 0.96 9.0 3.6 2.5 2 0 0 2 2 2 0 BAR domain DUF4298 PF14131.6 KXX78467.1 - 4.3 7.4 5.4 2.3 8.2 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) MARVEL PF01284.23 KXX78468.1 - 9.1e-06 25.8 13.1 1.4e-05 25.1 13.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 KXX78468.1 - 0.021 15.2 1.8 0.021 15.2 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) DUF2304 PF10066.9 KXX78468.1 - 5.6 7.2 9.5 0.36 11.1 4.2 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) GMC_oxred_N PF00732.19 KXX78469.1 - 3.4e-76 256.5 0.0 4.5e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX78469.1 - 1.2e-34 119.9 0.0 2.3e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXX78469.1 - 0.00013 21.1 0.1 0.00022 20.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX78469.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX78469.1 - 0.0047 16.0 0.1 0.83 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXX78469.1 - 0.0081 15.8 2.8 0.095 12.3 2.8 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX78469.1 - 0.016 14.5 0.1 0.038 13.2 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Methyltransf_32 PF13679.6 KXX78470.1 - 4.4e-22 78.8 0.1 5.2e-21 75.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain zf-CHC2 PF01807.20 KXX78470.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 CHC2 zinc finger Fructosamin_kin PF03881.14 KXX78471.1 - 2.5e-39 135.2 0.0 3.3e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXX78471.1 - 1.2e-06 28.7 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family GGACT PF06094.12 KXX78472.1 - 3.1e-19 69.8 0.3 4.3e-19 69.3 0.3 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Glyco_hydro_61 PF03443.14 KXX78473.1 - 0.0024 17.8 0.0 0.0034 17.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 FAT PF02259.23 KXX78474.1 - 6.5e-76 255.8 5.5 2.6e-75 253.8 5.9 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXX78474.1 - 5.6e-27 95.2 0.0 1.6e-26 93.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Swi3 PF07962.12 KXX78474.1 - 0.0016 18.4 0.1 0.0078 16.2 0.0 2.3 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 TPR_17 PF13431.6 KXX78474.1 - 0.011 16.1 0.0 62 4.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat phiKZ_IP PF12699.7 KXX78474.1 - 0.44 9.6 1.8 23 4.0 0.5 2.7 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins DSHCT PF08148.12 KXX78475.1 - 5.2e-52 175.8 0.4 1.3e-51 174.6 0.4 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KXX78475.1 - 4.4e-39 133.4 0.0 5e-38 130.0 0.0 2.4 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KXX78475.1 - 1.6e-24 87.3 0.0 2.7e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KXX78475.1 - 7.2e-19 68.2 0.0 2.4e-18 66.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX78475.1 - 1.4e-06 28.6 0.0 7.8e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX78475.1 - 1.6e-05 25.0 0.0 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cut8 PF08559.10 KXX78475.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Inv-AAD PF18785.1 KXX78476.1 - 3e-51 172.6 0.0 3.5e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KXX78476.1 - 2.2e-13 50.0 0.0 3.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KXX78476.1 - 0.0049 16.8 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain ANAPC4_WD40 PF12894.7 KXX78477.1 - 1.3e-06 28.6 0.0 1.1 9.5 0.0 5.4 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 KXX78477.1 - 6.9e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXX78477.1 - 3.5e-05 24.5 0.1 0.0001 23.0 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.12 KXX78477.1 - 0.0027 17.6 0.0 0.0072 16.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain WD40 PF00400.32 KXX78477.1 - 0.0045 17.8 0.1 20 6.3 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF676 PF05057.14 KXX78477.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ACT_7 PF13840.6 KXX78478.1 - 6.4e-20 70.7 0.1 1.5e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 ACT domain UPF0029 PF01205.19 KXX78479.1 - 2.7e-33 114.5 0.0 4.3e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KXX78479.1 - 1.8e-09 37.9 0.0 3.9e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 RWD domain RabGAP-TBC PF00566.18 KXX78480.1 - 2.2e-32 112.5 0.1 1.6e-17 63.9 0.0 3.1 3 0 0 3 3 3 3 Rab-GTPase-TBC domain UQ_con PF00179.26 KXX78481.1 - 7e-41 139.2 0.0 8.6e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX78481.1 - 0.012 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KXX78481.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KXX78481.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.4 1 1 0 1 1 1 0 RWD domain Atrophin-1 PF03154.15 KXX78482.1 - 1.5 7.0 4.3 1.6 6.9 4.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family Trypan_PARP PF05887.11 KXX78482.1 - 4.1 7.4 10.0 4.7 7.2 10.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TPR_17 PF13431.6 KXX78483.1 - 0.077 13.4 0.1 39 4.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXX78483.1 - 0.11 13.2 17.0 6 7.6 1.9 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXX78483.1 - 0.15 11.9 2.0 25 4.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX78483.1 - 0.49 11.4 12.8 5.2 8.2 0.7 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXX78483.1 - 0.61 10.6 3.3 12 6.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Fasciclin PF02469.22 KXX78484.1 - 1.9e-42 144.5 0.0 3e-25 88.9 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain Phasin PF05597.11 KXX78485.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TPR_19 PF14559.6 KXX78486.1 - 2e-07 31.4 1.2 0.032 14.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX78486.1 - 0.024 14.9 0.0 0.081 13.2 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KXX78486.1 - 0.03 14.4 5.5 2.2 8.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXX78486.1 - 0.079 12.8 0.8 12 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX78486.1 - 0.081 13.6 6.3 34 5.4 0.4 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXX78486.1 - 5.3 7.3 9.8 0.42 10.8 0.8 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 KXX78487.1 - 2.5e-25 89.9 0.0 1.3e-24 87.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 KXX78487.1 - 2.2e-10 40.3 10.3 6.2e-10 38.9 10.3 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain TTSSLRR PF12468.8 KXX78487.1 - 0.073 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein DUF3446 PF11928.8 KXX78487.1 - 0.26 11.6 4.7 0.074 13.4 1.0 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain Methyltransf_23 PF13489.6 KXX78489.1 - 6.3e-18 65.1 0.0 9.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX78489.1 - 1.6e-08 35.1 0.0 3.8e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX78489.1 - 1.2e-07 31.6 0.0 1.4e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX78489.1 - 1.6e-06 28.7 0.0 1.2e-05 25.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX78489.1 - 3.5e-06 27.6 0.0 6.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXX78489.1 - 0.047 13.2 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 KXX78489.1 - 0.068 12.5 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXX78489.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KXX78489.1 - 0.12 11.7 0.0 16 4.7 0.0 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KXX78489.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Pal1 PF08316.11 KXX78490.1 - 1.8e-47 161.6 0.1 1.8e-47 161.6 0.1 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein CorA PF01544.18 KXX78491.1 - 9.3e-06 25.2 0.7 1.3e-05 24.7 0.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 KXX78492.1 - 2.9e-26 92.4 0.0 3.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78492.1 - 8.5e-14 51.5 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX78492.1 - 3.8e-09 35.8 0.0 6.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXX78492.1 - 0.00016 21.7 0.0 0.0015 18.5 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Exo_endo_phos PF03372.23 KXX78493.1 - 5.1e-05 22.9 0.0 0.00017 21.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family POP1 PF06978.11 KXX78494.1 - 1e-78 264.1 16.7 1e-78 264.1 16.7 3.5 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KXX78494.1 - 2e-28 98.6 0.9 6.9e-28 96.8 0.0 2.5 2 0 0 2 2 2 1 POPLD (NUC188) domain IBR PF01485.21 KXX78494.1 - 1.4e-10 41.2 25.9 2.2e-06 27.8 5.6 3.8 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KXX78494.1 - 6.4e-05 22.9 8.4 6.4e-05 22.9 8.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXX78494.1 - 0.0017 18.6 8.5 0.0017 18.6 8.5 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 KXX78494.1 - 0.16 11.7 4.9 0.48 10.2 4.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-B_box PF00643.24 KXX78494.1 - 4.1 7.6 8.5 0.46 10.7 2.0 2.5 2 0 0 2 2 2 0 B-box zinc finger HSP70 PF00012.20 KXX78495.1 - 2.1e-76 257.4 2.5 2.1e-76 257.4 2.5 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXX78495.1 - 1.4e-06 27.4 0.2 2.6e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KXX78495.1 - 0.0066 15.7 0.4 0.038 13.3 0.1 2.0 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase DUF3221 PF11518.8 KXX78495.1 - 0.036 14.4 0.9 0.094 13.1 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3221) TFIIF_alpha PF05793.12 KXX78495.1 - 0.061 11.9 7.8 0.099 11.2 7.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.6 KXX78495.1 - 0.18 11.5 2.3 0.45 10.2 2.3 1.6 1 0 0 1 1 1 0 FAM176 family Gar1 PF04410.14 KXX78495.1 - 0.32 10.7 3.9 0.77 9.5 3.9 1.6 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region DNA_pol_phi PF04931.13 KXX78495.1 - 2.4 6.1 8.4 3.7 5.5 8.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 KXX78495.1 - 2.5 8.5 6.8 5.9 7.3 6.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KXX78495.1 - 9.6 5.4 8.9 15 4.8 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein NT-C2 PF10358.9 KXX78496.1 - 2e-20 73.0 0.0 1.5e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins zf-C2H2 PF00096.26 KXX78497.1 - 3.5e-07 30.3 25.3 0.0018 18.7 2.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type Sina PF03145.16 KXX78497.1 - 0.001 19.1 13.1 0.013 15.5 10.4 2.1 1 1 1 2 2 2 1 Seven in absentia protein family zf-C2H2_4 PF13894.6 KXX78497.1 - 0.004 17.9 22.4 0.7 10.9 2.5 3.7 3 1 0 3 3 3 3 C2H2-type zinc finger Adeno_E3_CR2 PF02439.15 KXX78497.1 - 0.0059 16.3 0.8 0.011 15.5 0.8 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 zf-H2C2_5 PF13909.6 KXX78497.1 - 0.029 14.1 10.3 0.05 13.4 1.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KXX78497.1 - 0.092 13.4 8.6 0.43 11.2 1.8 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain PTP_tm PF18861.1 KXX78497.1 - 0.19 11.7 0.7 0.29 11.1 0.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J zf-C2H2_aberr PF17017.5 KXX78497.1 - 1 9.5 7.2 0.079 13.1 1.2 1.9 2 0 0 2 2 2 0 Aberrant zinc-finger zf-met2 PF12907.7 KXX78497.1 - 4.2 7.6 11.8 9.5 6.5 0.2 3.7 4 0 0 4 4 4 0 Zinc-binding Rrp40_N PF18311.1 KXX78498.1 - 3.4e-19 68.5 0.9 8.2e-19 67.3 0.9 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KXX78498.1 - 3.5e-16 59.3 0.7 7e-16 58.3 0.2 1.8 2 0 0 2 2 2 1 KH domain ATP_bind_1 PF03029.17 KXX78499.1 - 2.2e-72 243.7 0.0 5e-72 242.6 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KXX78499.1 - 3.2e-06 26.8 1.4 0.00013 21.6 0.0 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXX78499.1 - 4.6e-06 25.8 0.0 0.011 14.7 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KXX78499.1 - 0.00068 19.9 0.0 0.0045 17.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXX78499.1 - 0.001 19.1 0.0 0.0032 17.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KXX78499.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KXX78499.1 - 0.002 17.9 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXX78499.1 - 0.0021 17.3 0.1 0.0059 15.8 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain G-alpha PF00503.20 KXX78499.1 - 0.0032 16.7 0.2 0.088 11.9 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit NACHT PF05729.12 KXX78499.1 - 0.0039 17.1 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 KXX78499.1 - 0.005 17.0 0.8 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXX78499.1 - 0.0058 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KXX78499.1 - 0.0058 16.4 0.0 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 KXX78499.1 - 0.0059 16.1 0.0 0.16 11.5 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_23 PF13476.6 KXX78499.1 - 0.0067 17.0 0.1 3.6 8.0 0.2 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXX78499.1 - 0.0072 16.2 0.0 4.4 7.2 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KXX78499.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 KXX78499.1 - 0.013 15.8 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KXX78499.1 - 0.015 15.0 0.0 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KXX78499.1 - 0.017 15.7 0.4 0.44 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 KXX78499.1 - 0.019 14.5 0.0 2.2 7.7 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.19 KXX78499.1 - 0.022 14.4 0.1 0.23 11.0 0.1 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 KXX78499.1 - 0.061 13.0 0.5 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 KXX78499.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KXX78499.1 - 0.084 12.8 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KXX78499.1 - 0.085 12.9 0.3 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 KXX78499.1 - 0.092 13.1 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain CwfJ_C_2 PF04676.14 KXX78501.1 - 9e-29 100.3 0.3 9e-29 100.3 0.3 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KXX78501.1 - 3.3e-24 85.1 0.0 1.8e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DEAD PF00270.29 KXX78502.1 - 3.4e-46 157.2 0.0 6e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX78502.1 - 1.7e-29 102.4 0.0 7.1e-29 100.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX78502.1 - 7.9e-07 29.2 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXX78502.1 - 0.027 14.8 0.0 0.079 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KXX78502.1 - 0.084 12.8 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain ChAPs PF09295.10 KXX78503.1 - 9.7e-153 508.8 0.0 1.2e-152 508.5 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KXX78503.1 - 5.1e-05 23.8 3.4 0.39 11.7 0.6 4.7 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX78503.1 - 5.7e-05 22.9 0.4 0.045 13.9 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX78503.1 - 0.00013 22.3 1.0 2 9.0 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXX78503.1 - 0.0004 20.5 0.2 0.042 14.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX78503.1 - 0.0015 18.6 0.0 0.24 11.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX78503.1 - 0.0029 17.5 0.6 3.1 8.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX78503.1 - 0.0041 16.9 0.1 1.8 8.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXX78503.1 - 0.016 15.8 0.3 24 5.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXX78503.1 - 0.076 13.3 0.5 11 6.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KXX78504.1 - 4e-45 154.3 0.0 2.7e-43 148.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.23 KXX78505.1 - 1.5e-17 64.1 0.0 2.7e-17 63.3 0.0 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KXX78505.1 - 2.4e-07 31.2 0.0 3.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXX78505.1 - 0.00034 20.5 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.13 KXX78506.1 - 1.1e-15 57.0 3.2 1.4e-15 56.6 3.2 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit GFA PF04828.14 KXX78506.1 - 0.0053 17.1 0.2 1.3 9.5 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KXX78506.1 - 0.0086 16.1 0.4 0.012 15.6 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF3268 PF11672.8 KXX78506.1 - 0.021 15.2 0.4 0.18 12.1 0.4 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain zf_UBZ PF18439.1 KXX78506.1 - 0.025 14.2 0.2 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ISL3 PF14690.6 KXX78506.1 - 0.055 14.2 0.8 0.094 13.4 0.1 1.7 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2197 PF09963.9 KXX78506.1 - 0.058 13.7 1.1 1.3 9.3 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) HypA PF01155.19 KXX78506.1 - 0.061 13.4 0.3 0.077 13.0 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbon_6 PF10005.9 KXX78506.1 - 0.066 13.9 0.1 0.081 13.6 0.1 1.1 1 0 0 1 1 1 0 zinc-ribbon domain Brix PF04427.18 KXX78507.1 - 2.5e-48 164.8 0.0 3.5e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Tim54 PF11711.8 KXX78507.1 - 0.54 9.0 13.9 0.86 8.3 13.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AP3D1 PF06375.11 KXX78507.1 - 0.7 10.1 16.3 1.7 8.9 12.2 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PBP_sp32 PF07222.12 KXX78507.1 - 3.1 7.2 9.4 39 3.6 10.4 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Med7 PF05983.11 KXX78508.1 - 0.0091 16.1 0.0 0.0097 16.0 0.0 1.2 1 0 0 1 1 1 1 MED7 protein Methyltransf_23 PF13489.6 KXX78511.1 - 1.1e-22 80.6 0.0 1.5e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX78511.1 - 1.6e-12 47.5 0.0 1.2e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX78511.1 - 1.2e-10 42.0 0.0 2.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX78511.1 - 2.9e-07 31.0 0.0 7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX78511.1 - 2.3e-05 25.1 0.0 0.00026 21.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXX78511.1 - 0.0012 18.3 0.0 0.0054 16.2 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXX78511.1 - 0.0038 16.8 0.0 0.0093 15.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KXX78511.1 - 0.0059 16.7 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXX78511.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXX78511.1 - 0.095 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXX78511.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF87 PF01935.17 KXX78512.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Pirin_C PF05726.13 KXX78514.1 - 0.0033 17.7 0.0 9.9 6.6 0.0 3.1 3 0 0 3 3 3 3 Pirin C-terminal cupin domain HET PF06985.11 KXX78515.1 - 5.1e-21 75.6 0.0 8.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KXX78516.1 - 9e-20 70.9 54.6 3e-13 49.4 31.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin_N PF00134.23 KXX78517.1 - 2.1e-14 53.3 0.0 3.4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KXX78517.1 - 1.2e-07 32.2 0.1 2.7e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin Kisspeptin PF15152.6 KXX78517.1 - 6.6 7.6 6.5 0.55 11.0 0.2 2.3 2 1 1 3 3 3 0 Kisspeptin GST_N_4 PF17172.4 KXX78518.1 - 8.6e-23 81.0 0.0 1.8e-22 79.9 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXX78518.1 - 1.3e-07 31.3 0.0 3.9e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXX78518.1 - 1.4e-06 28.6 0.0 2.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KXX78518.1 - 0.0023 17.9 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 KXX78520.1 - 4.2e-51 174.1 0.0 5.8e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KXX78521.1 - 3.4e-71 239.7 0.0 4.3e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78521.1 - 3.7e-31 108.4 0.0 4.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXX78521.1 - 0.0021 17.1 0.0 0.024 13.6 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KXX78521.1 - 0.0027 17.1 0.0 0.0048 16.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXX78521.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXX78521.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.6 KXX78522.1 - 3.1e-31 109.1 0.0 5.4e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1996 PF09362.10 KXX78524.1 - 1.9e-58 198.3 0.1 2.1e-58 198.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gal_mutarotas_2 PF13802.6 KXX78524.1 - 0.22 11.9 1.3 0.79 10.1 0.1 2.4 3 0 0 3 3 3 0 Galactose mutarotase-like Ank_4 PF13637.6 KXX78525.1 - 3.8e-27 94.3 0.4 7.3e-09 36.0 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX78525.1 - 1.8e-24 86.1 0.5 8.7e-13 48.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX78525.1 - 3.7e-20 71.4 8.5 0.0002 21.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KXX78525.1 - 4.1e-18 63.6 2.2 0.0017 18.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXX78525.1 - 1.4e-16 60.3 7.4 3.5e-07 30.4 0.1 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KXX78525.1 - 1e-08 34.9 5.4 0.071 13.0 0.2 3.3 3 0 0 3 3 3 3 von Willebrand factor type A C-terminal domain Imm_superinfect PF14373.6 KXX78525.1 - 0.025 14.5 0.2 62 3.6 0.0 4.0 4 0 0 4 4 4 0 Superinfection immunity protein Virulence_fact PF13769.6 KXX78525.1 - 0.043 14.0 0.0 14 6.0 0.0 2.8 3 0 0 3 3 3 0 Virulence factor CadC_C1 PF18500.1 KXX78525.1 - 0.063 13.4 0.0 40 4.3 0.0 3.0 3 0 0 3 3 3 0 CadC C-terminal domain 1 Ldi PF18566.1 KXX78525.1 - 0.079 12.4 0.1 9 5.7 0.0 2.4 1 1 1 2 2 2 0 Linalool dehydratase/isomerase APCDDC PF14921.6 KXX78525.1 - 0.089 12.2 0.0 4.5 6.6 0.0 2.0 1 1 1 2 2 2 0 Adenomatosis polyposis coli down-regulated 1 WD40 PF00400.32 KXX78527.1 - 9.5e-26 89.6 8.5 1.9e-12 47.5 0.8 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat NACHT PF05729.12 KXX78527.1 - 1.8e-10 41.0 0.1 8.9e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ANAPC4_WD40 PF12894.7 KXX78527.1 - 5.8e-08 32.9 0.0 0.0086 16.4 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX78527.1 - 7.1e-07 28.2 0.5 0.0028 16.4 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AAA_16 PF13191.6 KXX78527.1 - 2.3e-06 28.1 0.1 8.7e-06 26.2 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX78527.1 - 0.0054 17.0 0.0 0.018 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KXX78527.1 - 0.014 14.7 0.3 0.032 13.5 0.3 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 KXX78527.1 - 0.024 15.2 0.0 0.63 10.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KXX78527.1 - 0.064 12.4 0.1 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NYN_YacP PF05991.11 KXX78527.1 - 0.13 12.2 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 YacP-like NYN domain Ge1_WD40 PF16529.5 KXX78527.1 - 0.2 10.6 4.0 0.36 9.7 1.3 2.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sugar_tr PF00083.24 KXX78528.1 - 4.5e-108 362.0 26.0 5.4e-108 361.7 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX78528.1 - 1e-16 60.8 30.8 1e-16 60.8 30.8 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Trehalase PF01204.18 KXX78528.1 - 0.043 12.7 2.0 0.46 9.3 0.0 2.6 3 0 0 3 3 3 0 Trehalase DUF4360 PF14273.6 KXX78529.1 - 0.0044 16.9 0.0 0.0055 16.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MIF4G PF02854.19 KXX78530.1 - 6.4e-22 78.2 0.1 3.1e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 KXX78530.1 - 1.2e-17 63.9 0.1 1.8e-16 60.1 0.1 3.0 3 1 0 3 3 3 1 MA3 domain SKG6 PF08693.10 KXX78531.1 - 2.4e-06 26.8 0.0 5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXX78531.1 - 0.0089 16.1 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.6 KXX78531.1 - 0.064 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_UL49_2 PF04823.12 KXX78531.1 - 0.092 12.9 0.3 0.19 11.9 0.3 1.5 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Med13_C PF06333.12 KXX78531.1 - 0.28 10.4 5.0 0.38 10.0 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Sporozoite_P67 PF05642.11 KXX78531.1 - 0.3 9.1 9.5 0.33 9.0 9.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MGC-24 PF05283.11 KXX78531.1 - 9.5 6.7 12.3 20 5.6 12.3 1.6 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_47 PF01532.20 KXX78532.1 - 4.2e-164 546.8 0.0 4.8e-164 546.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pyr_redox_2 PF07992.14 KXX78533.1 - 6.7e-63 212.6 10.6 1.6e-62 211.4 10.2 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXX78533.1 - 1.8e-39 134.4 0.0 7e-39 132.5 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXX78533.1 - 3e-24 85.4 11.9 3.3e-21 75.6 2.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX78533.1 - 8.4e-12 45.2 4.2 1.7e-06 28.1 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXX78533.1 - 9.9e-11 41.3 9.9 7.1e-09 35.2 2.6 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXX78533.1 - 2.1e-10 40.3 7.7 1.2e-06 27.9 2.3 3.3 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 KXX78533.1 - 4.2e-10 39.6 7.3 6.5e-09 35.6 0.3 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXX78533.1 - 1.5e-08 34.3 1.2 0.0048 16.2 0.2 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KXX78533.1 - 6.6e-08 32.5 13.8 0.0018 17.9 0.4 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX78533.1 - 4.3e-06 25.7 14.6 0.00011 21.1 1.8 3.8 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 KXX78533.1 - 6.3e-06 25.6 2.4 0.0003 20.1 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KXX78533.1 - 0.00013 21.4 9.7 0.0038 16.5 0.2 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX78533.1 - 0.00038 19.8 9.2 0.12 11.6 1.3 3.3 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 KXX78533.1 - 0.00059 19.0 3.0 0.065 12.3 0.1 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KXX78533.1 - 0.0071 15.7 1.0 3 7.2 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 KXX78533.1 - 0.031 13.4 2.4 1.7 7.7 0.0 3.2 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KXX78533.1 - 0.031 14.7 5.9 1.2 9.6 0.3 3.0 3 1 0 3 3 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KXX78533.1 - 0.08 11.8 6.4 0.061 12.2 0.7 2.2 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 KXX78533.1 - 1.1 8.8 5.1 3.4 7.2 0.3 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KXX78533.1 - 2.6 7.9 9.6 0.31 10.9 1.3 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NUDIX_2 PF13869.6 KXX78534.1 - 1.2e-46 158.7 0.0 3e-31 108.5 0.0 2.0 1 1 1 2 2 2 2 Nucleotide hydrolase UPF0047 PF01894.17 KXX78535.1 - 7.3e-36 122.8 0.0 9.4e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 SMC_N PF02463.19 KXX78536.1 - 3.4e-24 85.5 0.0 2e-23 83.0 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXX78536.1 - 3e-10 40.4 8.3 3e-10 40.4 8.3 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXX78536.1 - 4.4e-08 33.9 44.3 4.4e-08 33.9 44.3 5.9 2 2 1 3 3 3 1 AAA domain AAA_13 PF13166.6 KXX78536.1 - 6.7e-05 21.8 3.6 6.7e-05 21.8 3.6 5.4 3 2 2 5 5 5 3 AAA domain AAA_29 PF13555.6 KXX78536.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KXX78536.1 - 0.0019 18.4 0.0 0.0061 16.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KXX78536.1 - 0.0025 17.7 1.4 0.0025 17.7 1.4 3.7 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Laminin_II PF06009.12 KXX78536.1 - 9.6 6.2 54.2 0.082 12.9 1.0 7.1 4 2 3 7 7 7 0 Laminin Domain II COQ9 PF08511.11 KXX78537.1 - 1.2e-29 101.9 0.1 5e-29 99.9 0.0 1.9 2 0 0 2 2 2 1 COQ9 Emaravirus_P4 PF16505.5 KXX78537.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily RRM_1 PF00076.22 KXX78538.1 - 1.4e-49 165.7 0.0 6e-18 64.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXX78538.1 - 0.00016 21.7 0.5 7.1 6.8 0.0 4.2 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 KXX78538.1 - 0.00017 21.6 0.0 0.91 9.6 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.10 KXX78538.1 - 0.0016 18.0 0.0 0.047 13.2 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RRM_5 PF13893.6 KXX78538.1 - 0.026 14.1 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PknH_C PF14032.6 KXX78538.1 - 0.03 14.2 3.2 5.6 6.8 0.0 3.4 4 0 0 4 4 4 0 PknH-like extracellular domain RRM_occluded PF16842.5 KXX78538.1 - 0.069 13.0 0.0 6.4 6.7 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif Keratin_2_head PF16208.5 KXX78538.1 - 0.079 13.1 45.5 0.46 10.6 8.3 2.6 2 0 0 2 2 2 0 Keratin type II head SRP14 PF02290.15 KXX78539.1 - 9.8e-31 106.0 0.0 1.4e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein SF3a60_bindingd PF12108.8 KXX78539.1 - 0.047 13.6 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain FA_desaturase PF00487.24 KXX78540.1 - 8.4e-29 101.2 25.2 1.3e-28 100.6 25.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXX78540.1 - 2.3e-13 50.1 0.0 4.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Vac14_Fig4_bd PF11916.8 KXX78541.1 - 1.6e-81 272.3 9.1 1.6e-81 272.3 9.1 1.6 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KXX78541.1 - 2.1e-44 150.1 0.0 2.8e-41 140.0 0.0 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KXX78541.1 - 1.3e-07 31.2 0.2 0.00066 19.7 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KXX78541.1 - 1.8e-07 31.5 3.6 0.0058 17.1 0.1 5.1 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 KXX78541.1 - 6.8e-07 29.5 0.6 0.0012 18.9 0.5 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KXX78541.1 - 0.0045 17.0 0.0 1.3 9.2 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXX78541.1 - 0.0096 16.3 2.6 1.7 9.1 0.0 4.5 5 1 1 6 6 6 1 HEAT repeats THUMP PF02926.17 KXX78542.1 - 5.2e-09 36.3 0.0 9.7e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 THUMP domain TPP_enzyme_N PF02776.18 KXX78543.1 - 1.7e-34 118.9 0.1 2.1e-33 115.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXX78543.1 - 4.8e-21 74.9 0.0 1.2e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXX78543.1 - 6e-15 55.3 0.3 2.7e-14 53.2 0.0 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXX78543.1 - 0.097 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SGT1 PF07093.11 KXX78544.1 - 3.4e-96 323.0 6.0 2.6e-81 273.8 0.0 2.2 2 0 0 2 2 2 2 SGT1 protein Parathyroid PF01279.17 KXX78545.1 - 0.14 12.7 0.3 3.6 8.3 0.0 2.7 3 0 0 3 3 3 0 Parathyroid hormone family Sds3 PF08598.11 KXX78546.1 - 0.056 13.4 1.1 0.11 12.4 1.1 1.5 1 0 0 1 1 1 0 Sds3-like Rad60-SLD PF11976.8 KXX78546.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2431 PF10354.9 KXX78547.1 - 2.3e-57 193.9 0.0 3.4e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) NOA36 PF06524.12 KXX78548.1 - 0.016 14.5 9.8 0.026 13.8 9.8 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KXX78548.1 - 0.03 13.8 5.2 0.046 13.1 5.2 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KXX78548.1 - 0.076 11.1 11.7 0.1 10.6 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KXX78548.1 - 0.09 11.1 6.0 0.14 10.4 6.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Cucumo_2B PF03263.13 KXX78548.1 - 0.15 12.5 0.6 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 Cucumovirus protein 2B RXT2_N PF08595.11 KXX78548.1 - 0.16 12.0 3.9 0.43 10.6 3.9 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Utp14 PF04615.13 KXX78548.1 - 0.7 8.4 3.7 1 7.8 3.7 1.3 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.12 KXX78548.1 - 0.84 7.8 6.2 1.2 7.3 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KXX78548.1 - 1 9.0 14.2 0.07 12.9 8.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KXX78548.1 - 1.9 7.7 8.0 2.7 7.2 8.0 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 KXX78548.1 - 2.9 7.7 7.5 5.2 6.9 7.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region ThiF PF00899.21 KXX78549.1 - 4e-24 85.3 0.0 5.5e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF2841 PF11001.8 KXX78550.1 - 1.1e-36 125.7 1.0 1.7e-36 125.0 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF5394 PF17372.2 KXX78550.1 - 0.087 12.4 0.4 0.13 11.8 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5394) HypA PF01155.19 KXX78550.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ABC_membrane PF00664.23 KXX78551.1 - 1.8e-87 293.5 34.5 5.7e-46 157.4 6.8 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXX78551.1 - 4.1e-52 176.3 1.0 1.7e-29 103.0 0.1 3.5 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KXX78551.1 - 8.9e-09 35.1 3.6 0.007 15.8 0.0 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXX78551.1 - 7.8e-06 26.0 0.3 0.28 11.3 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX78551.1 - 5.8e-05 23.1 0.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KXX78551.1 - 0.0022 18.1 0.5 0.3 11.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KXX78551.1 - 0.0028 17.4 2.5 3.1 7.6 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXX78551.1 - 0.0049 17.4 1.2 0.74 10.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXX78551.1 - 0.0061 17.0 0.4 0.16 12.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KXX78551.1 - 0.02 15.0 0.9 0.85 9.7 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 KXX78551.1 - 0.026 14.3 0.2 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane_2 PF06472.15 KXX78551.1 - 0.17 11.3 5.8 0.15 11.4 0.5 2.7 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 NACHT PF05729.12 KXX78551.1 - 0.23 11.4 2.0 0.61 10.0 0.1 2.6 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KXX78551.1 - 0.32 10.7 3.6 1.7 8.4 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KXX78551.1 - 0.35 10.5 2.8 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain MWFE PF15879.5 KXX78551.1 - 0.69 10.1 5.0 2.4 8.4 0.5 3.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit AAA_22 PF13401.6 KXX78551.1 - 0.75 10.1 2.6 55 4.0 0.1 3.2 2 1 0 2 2 2 0 AAA domain Cnn_1N PF07989.11 KXX78552.1 - 9.1e-20 70.6 3.1 9.1e-20 70.6 3.1 17.6 5 4 10 15 15 15 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KXX78552.1 - 2.4e-19 69.7 6.1 2.4e-19 69.7 6.1 7.2 5 3 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TPR_MLP1_2 PF07926.12 KXX78552.1 - 4.2e-05 23.6 43.8 0.0001 22.4 14.5 12.7 2 2 8 11 11 11 5 TPR/MLP1/MLP2-like protein GAS PF13851.6 KXX78552.1 - 0.001 18.4 34.1 0.001 18.4 34.1 10.6 1 1 8 10 10 10 2 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KXX78552.1 - 0.0019 16.9 30.7 0.0019 16.9 30.7 6.1 1 1 6 7 7 7 2 AAA domain Fez1 PF06818.15 KXX78552.1 - 0.002 18.6 25.8 0.002 18.6 25.8 9.3 1 1 7 8 8 8 2 Fez1 DUF3450 PF11932.8 KXX78552.1 - 0.0041 16.5 17.7 0.0041 16.5 17.7 12.3 3 1 9 12 12 12 3 Protein of unknown function (DUF3450) NIT PF08376.10 KXX78553.1 - 0.0068 16.9 9.7 0.0068 16.9 9.7 2.3 2 1 0 2 2 2 1 Nitrate and nitrite sensing Takusan PF04822.13 KXX78553.1 - 0.024 14.5 3.0 0.031 14.2 0.1 2.6 3 0 0 3 3 3 0 Takusan DUF4611 PF15387.6 KXX78553.1 - 0.19 12.0 5.7 2.3 8.5 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) GMC_oxred_N PF00732.19 KXX78554.1 - 9.3e-55 186.1 0.0 1.2e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX78554.1 - 2.6e-36 125.3 0.0 4.6e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXX78554.1 - 0.00016 21.4 1.0 0.0046 16.6 0.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX78554.1 - 0.00071 19.8 0.2 0.0016 18.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX78554.1 - 0.00075 18.7 2.1 0.0015 17.7 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX78554.1 - 0.007 15.6 0.3 0.016 14.4 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX78554.1 - 0.013 14.6 0.6 0.21 10.6 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KXX78554.1 - 0.031 14.3 0.4 0.54 10.2 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXX78554.1 - 0.033 13.0 0.1 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 KXX78554.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KXX78554.1 - 0.091 12.0 0.4 0.76 9.0 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KXX78555.1 - 4.6e-09 36.1 0.0 6.6e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX78555.1 - 8.3e-07 29.1 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXX78555.1 - 0.00032 21.1 0.0 0.00062 20.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXX78555.1 - 0.0013 18.0 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 KXX78555.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 KXX78555.1 - 0.066 12.8 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 KXX78555.1 - 0.098 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Myb_DNA-binding PF00249.31 KXX78556.1 - 3.5e-39 132.7 12.5 1.6e-13 50.6 0.8 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXX78556.1 - 3.7e-30 104.0 7.7 9.9e-13 48.1 0.7 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXX78556.1 - 0.00065 19.5 0.1 0.029 14.2 0.0 2.5 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 KXX78556.1 - 0.0014 18.7 5.8 0.67 10.1 0.1 3.4 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 KXX78556.1 - 0.02 15.1 0.4 4.9 7.4 0.1 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KXX78556.1 - 0.038 14.0 0.0 23 5.1 0.0 3.1 2 1 1 3 3 3 0 SLIDE Myb_DNA-bind_2 PF08914.11 KXX78556.1 - 0.082 13.1 1.1 7.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Rap1 Myb domain MADF_DNA_bdg PF10545.9 KXX78556.1 - 0.088 13.1 4.3 9.6 6.6 0.1 3.2 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PAN_4 PF14295.6 KXX78557.1 - 3.1e-06 27.0 1.9 5.8e-06 26.1 1.9 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXX78557.1 - 0.009 16.0 0.4 0.018 15.0 0.4 1.4 1 0 0 1 1 1 1 PAN domain ETRAMP PF09716.10 KXX78557.1 - 0.14 12.3 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) APH PF01636.23 KXX78558.1 - 2.2e-08 34.3 1.7 3.6e-08 33.6 0.5 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ferric_reduct PF01794.19 KXX78559.1 - 2.3e-20 72.9 9.8 6.7e-20 71.5 9.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXX78559.1 - 5.2e-07 29.7 0.0 0.0069 16.5 0.0 2.7 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.12 KXX78559.1 - 3.7e-05 23.9 0.0 0.036 14.2 0.1 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain SR-25 PF10500.9 KXX78559.1 - 0.43 10.1 5.3 0.66 9.5 5.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 KXX78564.1 - 1.3e-09 38.5 0.6 0.068 14.1 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat SGL PF08450.12 KXX78564.1 - 0.0093 15.6 0.0 0.15 11.6 0.0 2.0 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 KXX78564.1 - 0.14 12.5 0.0 1.1 9.6 0.0 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX78565.1 - 2e-06 28.4 0.8 0.18 12.8 0.2 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat CDC45 PF02724.14 KXX78565.1 - 1.5 7.1 8.0 2 6.6 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein YbfN PF13982.6 KXX78567.1 - 0.044 14.1 0.8 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 YbfN-like lipoprotein cwf21 PF08312.12 KXX78567.1 - 0.13 12.5 0.1 15 5.9 0.0 2.3 2 0 0 2 2 2 0 cwf21 domain AAA PF00004.29 KXX78568.1 - 1.9e-19 70.4 0.0 3.6e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX78568.1 - 0.00011 22.6 0.0 0.0018 18.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXX78568.1 - 0.00028 20.7 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXX78568.1 - 0.01 16.1 0.1 0.048 13.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXX78568.1 - 0.023 15.2 0.1 0.15 12.6 0.0 2.5 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KXX78568.1 - 0.032 14.2 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KXX78568.1 - 0.082 12.7 5.8 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain HET-s_218-289 PF11558.8 KXX78568.1 - 0.091 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Het-s 218-289 NPR3 PF03666.13 KXX78568.1 - 0.2 10.4 9.5 1.8 7.2 8.1 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 KXX78568.1 - 1.8 8.3 14.1 16 5.3 16.0 1.5 2 0 0 2 2 2 0 SpoIIIAH-like protein SURF2 PF05477.11 KXX78568.1 - 1.9 8.1 11.9 1.5e+02 2.0 13.6 2.3 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.12 KXX78568.1 - 3.2 7.0 11.2 6.3 6.0 11.2 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KXX78568.1 - 3.6 5.7 18.1 5.5 5.1 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 KXX78568.1 - 5.8 6.7 13.5 11 5.8 13.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4637 PF15470.6 KXX78568.1 - 7.6 6.2 12.7 14 5.4 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-RING_2 PF13639.6 KXX78569.1 - 2.4e-07 31.0 4.4 2.4e-07 31.0 4.4 2.2 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KXX78569.1 - 0.0011 19.1 6.1 0.0011 19.1 6.1 2.0 2 1 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 KXX78569.1 - 0.0042 17.0 3.2 0.0088 15.9 3.2 1.5 1 0 0 1 1 1 1 PHD-finger SWIM PF04434.17 KXX78569.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_UBOX PF13445.6 KXX78569.1 - 0.011 15.8 1.6 0.032 14.2 1.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXX78569.1 - 0.016 15.2 1.9 0.016 15.2 1.9 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger MFS_1 PF07690.16 KXX78570.1 - 3.7e-24 85.3 41.6 6e-22 78.0 28.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrolase_6 PF13344.6 KXX78571.1 - 7.8e-08 32.4 0.0 2.1e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase p450 PF00067.22 KXX78572.1 - 6.2e-66 223.0 0.0 7.1e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KXX78573.1 - 1.9e-25 89.4 0.0 8.1e-25 87.4 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX78573.1 - 7.6e-19 68.2 0.1 1.1e-18 67.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX78573.1 - 2.1e-10 40.8 0.0 3.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXX78573.1 - 4.4e-05 23.0 0.0 5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXX78573.1 - 7.9e-05 22.2 0.0 9.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SLD5_C PF16922.5 KXX78573.1 - 0.032 14.4 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Polysacc_synt_2 PF02719.15 KXX78573.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PUL PF08324.11 KXX78574.1 - 4e-62 210.0 0.3 5.5e-62 209.5 0.3 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KXX78574.1 - 1e-42 145.0 0.2 1.6e-42 144.3 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KXX78574.1 - 9.5e-30 102.2 12.4 3.2e-05 24.6 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.6 KXX78574.1 - 0.0073 16.8 0.0 0.31 11.6 0.0 3.0 2 0 0 2 2 2 1 PQQ-like domain Polbeta PF18765.1 KXX78575.1 - 1.1e-05 25.4 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RlaP PF10127.9 KXX78575.1 - 0.00012 21.7 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 KXX78575.1 - 0.00032 20.9 0.1 0.00066 19.9 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain Amidoligase_2 PF12224.8 KXX78576.1 - 5.2e-10 39.4 0.1 3.3e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme AAA PF00004.29 KXX78578.1 - 2.4e-07 31.2 0.1 6.7e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXX78578.1 - 0.052 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RGS PF00615.19 KXX78578.1 - 0.15 12.3 0.1 0.36 11.1 0.0 1.6 2 0 0 2 2 2 0 Regulator of G protein signaling domain MFS_1 PF07690.16 KXX78579.1 - 5.9e-45 153.7 65.1 3.5e-36 124.9 40.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXX78579.1 - 9.8e-06 24.7 21.5 0.0046 15.9 4.6 2.1 1 1 1 2 2 2 2 MFS_1 like family Acyl-CoA_dh_1 PF00441.24 KXX78580.1 - 4.2e-22 79.0 1.3 4.2e-22 79.0 1.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXX78580.1 - 9.7e-09 35.9 0.4 2.2e-08 34.7 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXX78580.1 - 5.3e-07 29.8 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXX78580.1 - 1.3e-05 25.4 1.9 1.3e-05 25.4 1.9 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain T3SS_ExsE PF18286.1 KXX78580.1 - 0.15 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system ExsE p450 PF00067.22 KXX78581.1 - 1.2e-59 202.3 0.0 1.5e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EMP70 PF02990.16 KXX78581.1 - 0.57 8.8 2.8 0.27 9.9 0.2 1.7 2 0 0 2 2 2 0 Endomembrane protein 70 Glyco_hydro_8 PF01270.17 KXX78582.1 - 0.011 14.6 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 SRR1 PF07985.12 KXX78583.1 - 7.1e-09 35.6 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 SRR1 DUF3663 PF12404.8 KXX78584.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase DUF3040 PF11239.8 KXX78584.1 - 0.84 9.9 5.9 28 5.1 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) WD40 PF00400.32 KXX78587.1 - 3.2e-19 68.9 3.8 3.2e-09 37.3 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXX78587.1 - 1.5e-05 24.2 0.0 0.05 12.5 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KXX78587.1 - 0.00014 22.1 0.0 0.24 11.7 0.0 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KXX78589.1 - 9.6e-28 97.4 0.1 1.7e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Cellulase PF00150.18 KXX78590.1 - 0.00083 18.9 0.2 0.047 13.1 0.1 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) HET PF06985.11 KXX78593.1 - 1.1e-21 77.7 0.1 1.9e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SBD_N PF07005.11 KXX78594.1 - 0.0026 17.5 0.7 0.004 16.9 0.7 1.3 1 0 0 1 1 1 1 Sugar-binding N-terminal domain DUF948 PF06103.11 KXX78594.1 - 0.02 15.1 1.3 0.02 15.1 1.3 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DASH_Dad2 PF08654.10 KXX78594.1 - 0.084 13.3 0.3 0.34 11.3 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad2 NPP1 PF05630.11 KXX78595.1 - 1.1e-58 198.6 0.3 1.4e-58 198.3 0.3 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Mito_carr PF00153.27 KXX78596.1 - 7.8e-15 54.6 3.6 1.3e-09 37.8 0.1 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein Methyltransf_23 PF13489.6 KXX78597.1 - 1.3e-21 77.1 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX78597.1 - 1.2e-09 38.7 0.0 4.1e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX78597.1 - 2.5e-06 28.2 0.0 2e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX78597.1 - 3.5e-06 26.9 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX78597.1 - 3.3e-05 24.5 0.0 6.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXX78597.1 - 0.012 15.8 0.0 0.04 14.0 0.0 1.7 1 1 0 2 2 2 0 FtsJ-like methyltransferase Rad4 PF03835.15 KXX78598.1 - 6.4e-11 42.1 0.7 1.6e-10 40.8 0.7 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KXX78598.1 - 8.5e-08 32.6 1.2 1.8e-07 31.6 1.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 KXX78598.1 - 0.23 11.2 4.5 6.8 6.5 0.3 2.5 1 1 1 2 2 2 0 Cold-inducible protein YdjO E1-E2_ATPase PF00122.20 KXX78600.1 - 2.2e-50 170.7 3.6 5.9e-50 169.3 3.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXX78600.1 - 1.7e-26 93.9 0.1 3.4e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXX78600.1 - 4.7e-06 27.0 1.3 2.6e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KXX78600.1 - 0.0046 16.7 0.2 0.058 13.1 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SCAMP PF04144.13 KXX78600.1 - 4.6 7.5 7.0 0.89 9.8 2.0 2.2 2 0 0 2 2 2 0 SCAMP family Pkinase PF00069.25 KXX78601.1 - 2.7e-41 141.7 0.0 6.5e-38 130.6 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78601.1 - 2.7e-13 49.8 0.0 1.4e-07 31.1 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KXX78601.1 - 0.00066 19.7 0.1 0.03 14.3 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXX78601.1 - 0.017 13.9 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXX78601.1 - 0.019 14.3 0.0 5.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KXX78601.1 - 0.021 14.4 0.0 0.38 10.4 0.0 2.6 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Helicase_C_2 PF13307.6 KXX78602.1 - 5.2e-55 186.2 0.0 1.5e-54 184.7 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXX78602.1 - 9.6e-48 162.1 0.0 2e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KXX78602.1 - 0.0045 17.0 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXX78602.1 - 0.1 12.8 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF134 PF02001.16 KXX78603.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF134 SUZ-C PF12901.7 KXX78606.1 - 0.051 13.6 0.6 16 5.6 0.1 2.7 2 0 0 2 2 2 0 SUZ-C motif Microvir_lysis PF04517.12 KXX78607.1 - 0.19 11.7 1.3 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus Bestrophin PF01062.21 KXX78608.1 - 1.1 8.5 5.4 2.7 7.3 0.1 2.4 1 1 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Glyco_hydro2_C5 PF18565.1 KXX78609.1 - 4.3e-33 113.2 0.1 1e-32 112.0 0.1 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 KXX78609.1 - 6.6e-25 87.8 0.0 2.3e-24 86.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 KXX78609.1 - 3.7e-24 84.4 0.2 1.2e-23 82.8 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 KXX78609.1 - 2.8e-19 69.6 0.1 7.9e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KXX78609.1 - 5.5e-13 49.5 0.0 1.5e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KXX78609.1 - 0.00012 22.7 0.0 0.0011 19.6 0.0 2.7 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 KXX78609.1 - 0.00094 19.4 0.2 0.00094 19.4 0.2 2.7 3 0 0 3 3 3 1 Invasin, domain 3 Big_1 PF02369.16 KXX78609.1 - 0.0042 17.1 2.7 0.018 15.0 2.7 2.1 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) DUF3632 PF12311.8 KXX78610.1 - 1.1e-24 87.8 4.7 1.6e-24 87.3 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) SdpI PF13630.6 KXX78611.1 - 0.038 14.1 0.1 0.038 14.1 0.1 3.0 2 1 1 3 3 3 0 SdpI/YhfL protein family DUF1772 PF08592.11 KXX78611.1 - 0.053 13.8 4.5 2.8 8.2 0.4 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Ferric_reduct PF01794.19 KXX78611.1 - 1.2 9.3 11.2 1.1 9.3 9.3 2.0 1 1 0 1 1 1 0 Ferric reductase like transmembrane component MRP-S31 PF15433.6 KXX78613.1 - 0.0015 18.3 1.0 0.0018 18.0 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 APG6_N PF17675.1 KXX78613.1 - 0.0057 17.2 5.9 0.012 16.2 5.9 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region Macoilin PF09726.9 KXX78613.1 - 0.017 13.7 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF3584 PF12128.8 KXX78613.1 - 0.038 11.5 6.6 0.048 11.2 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BssS PF13991.6 KXX78613.1 - 0.074 13.1 0.2 0.074 13.1 0.2 2.2 3 0 0 3 3 3 0 BssS protein family Cep57_CLD_2 PF14197.6 KXX78613.1 - 0.11 12.6 16.2 0.92 9.6 1.0 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Prp19 PF08606.11 KXX78613.1 - 1.3 9.1 7.8 0.13 12.3 1.9 2.3 2 0 0 2 2 2 0 Prp19/Pso4-like TEX13 PF15186.6 KXX78613.1 - 2.2 8.0 10.3 0.33 10.6 1.8 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF1635 PF07795.11 KXX78613.1 - 3.5 7.4 8.9 4 7.2 6.5 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) Ank_2 PF12796.7 KXX78615.1 - 0.00037 21.0 0.0 0.00077 20.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Acetyltransf_7 PF13508.7 KXX78615.1 - 0.00046 20.5 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX78615.1 - 0.00074 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ank_4 PF13637.6 KXX78615.1 - 0.0012 19.4 0.0 0.0041 17.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) FR47 PF08445.10 KXX78615.1 - 0.0019 18.1 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KXX78615.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Ank_3 PF13606.6 KXX78615.1 - 0.0027 18.0 0.0 0.0095 16.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 KXX78615.1 - 0.0094 16.4 0.2 0.041 14.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXX78615.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Acetyltransf_10 PF13673.7 KXX78615.1 - 0.021 14.8 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXX78615.1 - 0.1 12.1 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Putative acetyl-transferase Peptidase_C14 PF00656.22 KXX78617.1 - 1.8e-05 24.8 0.0 6.9e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Caspase domain Kinesin PF00225.23 KXX78618.1 - 2.5e-57 194.3 0.0 4.5e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXX78618.1 - 1.4e-09 38.0 0.0 1.9e-07 31.2 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Jnk-SapK_ap_N PF09744.9 KXX78618.1 - 2.3 8.4 13.9 0.056 13.7 5.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF1640 PF07798.11 KXX78618.1 - 4.4 7.3 8.7 1.1 9.3 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) YabA PF06156.13 KXX78618.1 - 9.4 6.9 6.6 4.9 7.8 0.4 2.7 2 1 1 3 3 3 0 Initiation control protein YabA Tyrosinase PF00264.20 KXX78619.1 - 5e-42 144.7 0.0 6.2e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase adh_short PF00106.25 KXX78620.1 - 3.3e-20 72.4 1.0 6.6e-19 68.1 0.1 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX78620.1 - 7.9e-18 64.9 0.4 1e-17 64.5 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX78620.1 - 0.0052 16.7 0.5 0.063 13.2 0.0 2.2 1 1 1 2 2 2 2 KR domain NOA36 PF06524.12 KXX78621.1 - 5.1 6.3 15.3 15 4.8 15.3 1.7 1 0 0 1 1 1 0 NOA36 protein SesA PF17107.5 KXX78622.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases LMWPc PF01451.21 KXX78622.1 - 0.035 14.5 0.0 9.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase BCLP PF12304.8 KXX78624.1 - 0.14 11.7 11.0 0.027 14.0 1.1 2.7 2 1 0 2 2 2 0 Beta-casein like protein TNFR_16_TM PF18422.1 KXX78624.1 - 0.69 9.9 3.3 0.72 9.9 0.8 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain HlyIII PF03006.20 KXX78624.1 - 0.94 9.1 9.8 0.95 9.1 1.8 2.3 2 0 0 2 2 2 0 Haemolysin-III related FtsX PF02687.21 KXX78624.1 - 6.7 7.3 17.2 2e+02 2.5 8.7 3.3 1 1 1 2 2 2 0 FtsX-like permease family Esterase PF00756.20 KXX78625.1 - 1.1e-07 31.7 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXX78625.1 - 3.7e-05 23.3 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXX78625.1 - 0.00024 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX78625.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PLDc_N PF13396.6 KXX78626.1 - 4.1e-13 49.0 4.0 6e-13 48.5 4.0 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal Pox_A14 PF05767.12 KXX78626.1 - 0.045 13.9 0.2 0.06 13.5 0.2 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Glucos_trans_II PF14264.6 KXX78626.1 - 0.083 12.2 3.8 0.095 12.0 3.6 1.3 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF2207 PF09972.9 KXX78626.1 - 0.12 11.1 0.4 0.14 10.9 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.11 KXX78626.1 - 0.14 11.8 1.6 0.2 11.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Cation_ATPase_C PF00689.21 KXX78626.1 - 0.24 11.1 3.5 0.35 10.6 3.5 1.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Otopetrin PF03189.13 KXX78626.1 - 0.31 9.8 1.9 0.32 9.8 0.2 1.7 1 1 1 2 2 2 0 Otopetrin zf-C2H2_4 PF13894.6 KXX78628.1 - 0.05 14.5 0.8 5.8 8.0 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger CENP-B_dimeris PF09026.10 KXX78628.1 - 0.74 10.2 14.6 3.3 8.2 1.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM60A PF15396.6 KXX78628.1 - 0.86 9.6 4.6 0.66 9.9 0.2 2.4 2 0 0 2 2 2 0 Protein Family FAM60A DUF1996 PF09362.10 KXX78630.1 - 8.9e-56 189.5 0.0 2.9e-55 187.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_79C PF16862.5 KXX78631.1 - 3.7e-19 69.5 0.4 9.5e-19 68.2 0.4 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Gly_transf_sug PF04488.15 KXX78632.1 - 0.0079 16.8 0.0 0.0099 16.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF2781 PF10914.8 KXX78633.1 - 2.4e-33 115.6 9.7 2.7e-33 115.4 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF5542 PF17696.1 KXX78633.1 - 7 6.9 7.0 6.5 7.0 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5542) ApbA PF02558.16 KXX78634.1 - 1.1e-24 86.9 0.0 1.6e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXX78634.1 - 3.3e-10 40.2 0.0 6.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sel_put PF04328.13 KXX78634.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Selenoprotein, putative ABC_tran PF00005.27 KXX78635.1 - 6.4e-24 85.0 0.0 2.3e-10 41.1 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXX78635.1 - 4.9e-08 33.1 0.1 0.013 15.3 0.1 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXX78635.1 - 1.5e-06 28.4 0.0 0.0024 18.0 0.1 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXX78635.1 - 7.4e-05 22.4 0.0 0.043 13.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX78635.1 - 0.00098 19.4 0.0 0.62 10.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KXX78635.1 - 0.0014 19.2 0.1 0.046 14.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXX78635.1 - 0.0068 16.2 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXX78635.1 - 0.011 15.9 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX78635.1 - 0.017 15.5 0.0 1.5 9.2 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Ploopntkinase1 PF18748.1 KXX78635.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 TniB PF05621.11 KXX78635.1 - 0.036 13.5 0.0 7.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 KXX78635.1 - 0.068 13.7 0.0 7.3 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXX78635.1 - 0.072 12.9 0.1 3 7.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KXX78635.1 - 0.079 13.0 0.0 18 5.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXX78635.1 - 0.099 13.0 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KXX78635.1 - 0.1 13.0 0.1 0.74 10.2 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KXX78635.1 - 0.12 12.2 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 KXX78635.1 - 0.17 11.2 0.0 5.3 6.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KXX78635.1 - 0.23 11.1 0.0 8.5 6.1 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein UMP1 PF05348.11 KXX78636.1 - 5.6e-44 149.2 0.0 6.5e-44 148.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 KXX78637.1 - 6.7e-09 35.8 0.0 1.8e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXX78637.1 - 0.00018 22.1 0.2 0.00049 20.6 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KXX78637.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Adaptin_N PF01602.20 KXX78638.1 - 4.1e-124 415.0 10.0 5.1e-124 414.7 10.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXX78638.1 - 5.4e-56 189.1 0.2 5.4e-56 189.1 0.2 3.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXX78638.1 - 1.1e-16 61.0 4.9 4.2e-09 36.7 0.2 4.9 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KXX78638.1 - 1.1e-10 40.8 4.1 0.00013 21.9 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KXX78638.1 - 1.2e-05 25.6 3.0 15 6.3 0.1 6.3 6 0 0 6 6 6 2 HEAT-like repeat CLASP_N PF12348.8 KXX78638.1 - 0.00028 20.6 1.3 0.21 11.1 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.23 KXX78638.1 - 0.0012 18.8 1.9 2.6 8.2 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KXX78638.1 - 0.0071 16.5 1.3 1.4 9.1 0.1 3.5 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 KXX78638.1 - 0.054 13.5 0.1 9.3 6.3 0.0 3.9 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DUF1077 PF06417.12 KXX78639.1 - 5.6e-51 171.5 4.9 7.2e-51 171.2 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF3796 PF12676.7 KXX78639.1 - 0.015 15.7 0.1 0.02 15.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) MARVEL PF01284.23 KXX78640.1 - 2.7e-20 72.9 1.9 3.9e-20 72.4 1.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain Chitin_synth_1 PF01644.17 KXX78641.1 - 5.8e-78 260.5 0.4 8.7e-78 259.9 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXX78641.1 - 4.5e-28 97.0 0.2 9.7e-28 95.9 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXX78641.1 - 1.5e-22 79.9 6.0 1.7e-19 69.9 0.0 2.4 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXX78641.1 - 1.4e-08 34.9 0.4 1.4e-08 34.9 0.4 2.2 1 1 0 2 2 2 1 Glycosyl transferase family group 2 NIR_SIR PF01077.22 KXX78642.1 - 5.5e-55 185.2 1.1 6.8e-50 168.7 0.0 2.7 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KXX78642.1 - 9.6e-32 108.7 0.0 4.6e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KXX78642.1 - 5e-30 104.6 0.0 1.2e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KXX78642.1 - 2e-07 31.0 0.2 6.3e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.11 KXX78643.1 - 1.6e-52 178.2 8.6 3.6e-52 177.0 8.6 1.5 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_M56 PF05569.11 KXX78643.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Sugar_tr PF00083.24 KXX78644.1 - 8.5e-100 334.7 24.6 9.8e-100 334.5 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX78644.1 - 1.6e-29 103.0 52.2 1.1e-27 96.9 28.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX78644.1 - 2e-06 26.5 1.0 2e-06 26.5 1.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KXX78644.1 - 2 8.7 10.3 0.61 10.4 2.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) MFS_1 PF07690.16 KXX78645.1 - 3.5e-30 105.1 58.1 2.5e-29 102.3 58.1 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX78645.1 - 1.6e-15 56.6 12.8 1.6e-15 56.6 12.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_31 PF01055.26 KXX78646.1 - 3e-107 359.6 0.1 3.6e-107 359.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXX78646.1 - 6e-16 58.5 0.0 1.4e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.21 KXX78647.1 - 2.3e-59 201.4 0.0 3.4e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXX78647.1 - 1e-53 182.3 0.4 1.6e-53 181.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXX78647.1 - 5.8e-22 77.6 2.3 6.1e-22 77.5 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 KXX78647.1 - 0.003 17.8 0.2 0.012 15.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF11 Sugar-bind PF04198.13 KXX78647.1 - 0.027 13.6 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain TIP41 PF04176.13 KXX78649.1 - 1.3e-63 213.6 0.0 1.5e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 KXX78650.1 - 3.9e-72 242.8 0.0 4.8e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78650.1 - 3.4e-44 151.1 0.0 4.4e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX78650.1 - 2.5e-07 30.3 0.0 1.8e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXX78650.1 - 0.00059 19.2 0.1 0.00093 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXX78650.1 - 0.0058 15.6 1.2 0.034 13.1 1.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXX78650.1 - 0.015 14.9 0.0 0.048 13.2 0.0 1.7 2 1 0 3 3 3 0 RIO1 family APH PF01636.23 KXX78650.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXX78650.1 - 0.1 12.2 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KXX78650.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KXX78650.1 - 0.24 10.1 1.3 0.51 9.0 1.3 1.5 1 1 0 1 1 1 0 Fungal protein kinase Peptidase_M76 PF09768.9 KXX78651.1 - 1.2e-66 223.7 0.4 1.5e-66 223.4 0.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KXX78651.1 - 0.029 14.2 1.4 0.047 13.5 0.7 1.7 1 1 1 2 2 2 0 SprT-like family Peptidase_M91 PF14891.6 KXX78651.1 - 0.034 14.5 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Effector protein Creatinase_N_2 PF16189.5 KXX78652.1 - 1.5e-55 187.7 0.2 1.2e-53 181.5 0.2 2.6 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KXX78652.1 - 5.4e-46 156.9 0.0 8.5e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KXX78652.1 - 5.1e-23 82.2 0.0 1.7e-18 67.6 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KXX78652.1 - 1.9e-19 69.5 0.1 4.3e-19 68.3 0.1 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 FUN14 PF04930.15 KXX78653.1 - 1.2e-07 32.0 2.4 2.7e-07 30.9 2.4 1.5 1 0 0 1 1 1 1 FUN14 family CBFD_NFYB_HMF PF00808.23 KXX78654.1 - 2.3e-19 69.4 0.5 3.8e-19 68.7 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXX78654.1 - 5.7e-15 55.8 0.2 9.7e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KXX78654.1 - 0.041 14.2 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pol_alpha_B_N PF08418.10 KXX78654.1 - 0.16 11.9 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fcf2 PF08698.11 KXX78655.1 - 7.5e-32 109.6 0.0 1.3e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_60s PF00428.19 KXX78655.1 - 0.072 13.7 2.1 0.16 12.5 2.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sec15 PF04091.12 KXX78657.1 - 5.2e-107 357.9 0.9 5.2e-107 357.9 0.9 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.9 KXX78657.1 - 3.4e-05 23.7 1.2 7.1e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF4201 PF13870.6 KXX78657.1 - 0.0096 15.7 2.6 0.015 15.1 1.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF717 PF05338.12 KXX78657.1 - 0.044 13.9 0.7 0.57 10.3 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF717) Sec8_exocyst PF04048.14 KXX78657.1 - 0.092 12.6 5.5 0.37 10.7 1.6 3.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF3510 PF12022.8 KXX78657.1 - 0.11 12.9 1.9 9 6.7 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3510) DASH_Duo1 PF08651.10 KXX78657.1 - 0.11 12.3 2.3 0.47 10.3 0.5 3.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 BORCS8 PF10167.9 KXX78657.1 - 0.36 10.8 2.8 1.2 9.1 0.9 2.8 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 ApoLp-III PF07464.11 KXX78657.1 - 0.37 10.9 4.7 0.19 11.8 1.1 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) COG2 PF06148.11 KXX78657.1 - 1.3 9.1 10.6 2.5 8.2 1.3 4.2 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 KXX78657.1 - 1.3 9.1 7.2 0.17 11.9 1.3 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Spc29 PF17082.5 KXX78657.1 - 9.4 6.0 8.1 0.67 9.8 0.8 2.7 4 0 0 4 4 4 0 Spindle Pole Component 29 Sad1_UNC PF07738.13 KXX78658.1 - 1.6e-33 115.6 0.0 2.4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal tRNA-synt_1b PF00579.25 KXX78659.1 - 1.8e-71 240.8 0.0 2.7e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.22 KXX78659.1 - 9.3e-26 89.9 0.0 2.7e-25 88.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF5561 PF17716.1 KXX78659.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5561) RRM_2 PF04059.12 KXX78660.1 - 2.7e-36 123.6 0.3 5.5e-36 122.7 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KXX78660.1 - 0.00017 21.3 0.1 0.37 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_61 PF03443.14 KXX78663.1 - 4.7e-57 193.3 0.4 5.9e-57 192.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_6 PF12697.7 KXX78664.1 - 2.4e-10 41.4 9.6 4.4e-10 40.5 9.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX78664.1 - 8.2e-10 38.3 0.2 1.1e-09 37.9 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX78664.1 - 2.2e-08 34.1 0.2 3e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXX78664.1 - 0.00013 21.9 0.1 0.00019 21.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXX78664.1 - 0.081 12.7 0.1 0.16 11.7 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KXX78664.1 - 0.23 10.1 0.2 0.59 8.7 0.1 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase PF00151.19 KXX78664.1 - 0.25 10.6 0.1 0.39 10.0 0.1 1.2 1 0 0 1 1 1 0 Lipase MFS_1 PF07690.16 KXX78666.1 - 3.2e-31 108.6 64.1 2.2e-20 72.9 39.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX78666.1 - 0.0025 16.7 29.1 0.0084 15.0 16.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Spt5-NGN PF03439.13 KXX78667.1 - 1.3e-24 85.9 0.0 2.1e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 KXX78667.1 - 6.5e-24 84.3 38.1 1.1e-17 64.4 20.4 4.9 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 KXX78667.1 - 4.9e-20 72.4 10.8 4.9e-20 72.4 10.8 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KXX78667.1 - 2e-05 24.3 19.5 7e-05 22.6 0.8 5.1 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 KXX78667.1 - 0.066 13.5 0.2 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) Abhydrolase_1 PF00561.20 KXX78668.1 - 8.4e-16 58.4 0.0 1.1e-14 54.8 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX78668.1 - 5.8e-13 50.0 5.2 1.3e-12 48.9 5.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX78668.1 - 4.9e-12 45.6 0.0 2.9e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 UPF0227 PF05728.12 KXX78668.1 - 0.0061 16.5 0.0 1.8 8.5 0.0 2.5 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) DUF2048 PF09752.9 KXX78668.1 - 0.011 14.8 0.3 0.017 14.2 0.3 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_4 PF08386.10 KXX78668.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 KXX78668.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KXX78668.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KXX78668.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein NMT_C PF02799.15 KXX78669.1 - 4e-86 287.9 0.0 6e-86 287.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KXX78669.1 - 9.9e-62 207.5 0.0 2.5e-61 206.2 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KXX78669.1 - 2.2e-05 24.6 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX78669.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family eIF3_subunit PF08597.10 KXX78669.1 - 0.059 13.3 15.5 0.11 12.4 15.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PGA2 PF07543.12 KXX78669.1 - 0.53 10.3 9.1 0.97 9.4 9.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF5102 PF17104.5 KXX78669.1 - 2.4 8.1 5.3 9.3 6.2 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) UPF0239 PF06783.11 KXX78669.1 - 2.5 8.3 5.8 5.5 7.3 5.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) AA_permease_2 PF13520.6 KXX78671.1 - 3.6e-81 273.2 25.7 4.5e-81 272.9 25.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX78671.1 - 1e-09 37.5 22.6 1.5e-09 37.0 22.6 1.3 1 0 0 1 1 1 1 Amino acid permease Cyd_oper_YbgE PF09600.10 KXX78671.1 - 0.00073 19.9 1.9 0.00073 19.9 1.9 3.6 4 1 1 5 5 5 1 Cyd operon protein YbgE (Cyd_oper_YbgE) FGGY_C PF02782.16 KXX78672.1 - 1.4e-25 90.2 0.0 3.1e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXX78672.1 - 3.9e-21 75.7 0.0 4.7e-13 49.3 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Say1_Mug180 PF10340.9 KXX78672.1 - 3.8e-08 32.6 0.0 2.8e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KXX78672.1 - 1.3e-07 31.7 0.2 8.7e-07 29.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold CBFD_NFYB_HMF PF00808.23 KXX78673.1 - 3.2e-12 46.6 1.8 5.2e-12 45.9 1.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.13 KXX78673.1 - 0.018 15.0 30.8 0.033 14.2 30.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF702 PF05142.12 KXX78673.1 - 2.3 8.7 7.3 1.5 9.3 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Histone PF00125.24 KXX78673.1 - 3.4 8.1 10.1 0.27 11.6 4.0 2.3 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 PI3_PI4_kinase PF00454.27 KXX78674.1 - 2e-34 119.5 0.0 6.6e-34 117.8 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KXX78674.1 - 6e-20 71.0 0.0 1.3e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KXX78674.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 KXX78674.1 - 0.15 12.3 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal Pribosyl_synth PF14572.6 KXX78675.1 - 6.4e-43 146.9 3.7 1.2e-36 126.5 1.6 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXX78675.1 - 1.7e-29 102.1 0.0 4.4e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXX78675.1 - 3.6e-14 52.6 0.6 5.8e-14 51.9 0.6 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXX78675.1 - 0.12 11.8 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase WD40 PF00400.32 KXX78676.1 - 4.9e-21 74.6 15.0 0.00013 22.7 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX78676.1 - 6e-13 48.9 4.9 9.3e-05 22.7 0.3 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXX78676.1 - 7e-08 32.6 0.1 0.00033 20.6 0.1 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A tRNA_anti-like PF12869.7 KXX78676.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like Ge1_WD40 PF16529.5 KXX78676.1 - 0.15 11.0 0.1 0.86 8.5 0.0 2.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein M16C_assoc PF08367.11 KXX78677.1 - 4.4e-81 271.7 0.0 6.4e-81 271.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KXX78677.1 - 8.1e-33 114.0 0.0 7.1e-22 78.3 0.0 3.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXX78677.1 - 6e-09 36.0 0.0 1.9e-07 31.2 0.0 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) HHH_8 PF14716.6 KXX78677.1 - 0.091 13.1 0.0 0.59 10.5 0.0 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix domain Orn_Arg_deC_N PF02784.16 KXX78678.1 - 1.8e-83 279.7 0.0 2.5e-83 279.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXX78678.1 - 7.2e-20 71.0 0.0 9.5e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Taxilin PF09728.9 KXX78679.1 - 6.8e-89 298.1 61.4 2.2e-88 296.4 61.4 1.8 1 1 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 KXX78679.1 - 0.092 13.0 52.3 0.25 11.6 2.8 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4156 PF13698.6 KXX78679.1 - 3.7 8.0 6.1 1.5 9.2 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4156) NPV_P10 PF05531.12 KXX78679.1 - 6.4 7.3 17.5 0.73 10.3 3.3 4.1 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 KXX78679.1 - 6.9 6.8 51.4 1.8 8.7 23.1 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF2203 PF09969.9 KXX78679.1 - 8.1 7.2 30.3 0.12 13.1 1.6 4.4 2 1 3 5 5 5 0 Uncharacterized conserved protein (DUF2203) Acetyltransf_1 PF00583.25 KXX78681.1 - 1e-14 54.8 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX78681.1 - 1.1e-10 41.8 0.0 1.6e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX78681.1 - 1.9e-10 40.8 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX78681.1 - 6.9e-07 29.2 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXX78681.1 - 6.5e-05 23.0 0.0 9.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXX78681.1 - 0.0014 18.7 0.8 0.0031 17.7 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain NMO PF03060.15 KXX78683.1 - 1.5e-49 169.2 1.8 2.3e-49 168.6 1.8 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXX78683.1 - 4.3e-07 29.3 2.7 7.4e-06 25.2 2.7 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXX78683.1 - 0.0016 17.6 5.8 0.003 16.6 5.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase XS PF03468.14 KXX78684.1 - 0.083 13.2 0.0 0.09 13.1 0.0 1.1 1 0 0 1 1 1 0 XS domain Zw10 PF06248.13 KXX78685.1 - 4.6e-07 28.8 1.9 3.2e-06 26.0 1.9 2.1 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KXX78685.1 - 0.0083 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Com_YlbF PF06133.11 KXX78685.1 - 0.62 10.7 2.6 26 5.5 0.0 3.3 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Ribosomal_L36e PF01158.18 KXX78686.1 - 1.7e-41 140.3 5.7 2e-41 140.1 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 KXX78686.1 - 0.0082 16.3 0.6 0.01 16.0 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 UQ_con PF00179.26 KXX78687.1 - 2.3e-19 69.4 0.0 3.6e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX78687.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B DHHC PF01529.20 KXX78688.1 - 4.4e-39 133.7 7.5 4.4e-39 133.7 7.5 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4134 PF13572.6 KXX78688.1 - 0.004 17.4 0.3 0.0079 16.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4134) DUF3602 PF12223.8 KXX78688.1 - 0.13 12.9 2.0 15 6.3 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) PI-PLC-X PF00388.19 KXX78689.1 - 1.6e-58 196.4 0.0 3.3e-58 195.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXX78689.1 - 1.7e-42 144.4 0.0 3.6e-42 143.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KXX78689.1 - 2e-08 34.4 0.0 5.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 KXX78689.1 - 0.00011 22.5 0.0 0.00023 21.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_12 PF16457.5 KXX78689.1 - 0.015 15.8 0.5 0.041 14.4 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain GDPD PF03009.17 KXX78689.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family PH PF00169.29 KXX78689.1 - 0.13 12.7 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 PH domain SMC_N PF02463.19 KXX78690.1 - 7.3e-60 202.1 0.0 6.1e-59 199.1 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXX78690.1 - 2.5e-26 92.3 0.0 1.1e-25 90.2 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KXX78690.1 - 3.2e-11 44.1 19.3 3.2e-11 44.1 19.3 6.4 3 2 2 5 5 2 2 AAA domain AAA_15 PF13175.6 KXX78690.1 - 5.8e-10 39.4 8.2 5.8e-10 39.4 8.2 4.7 2 2 2 4 4 2 1 AAA ATPase domain AAA_21 PF13304.6 KXX78690.1 - 2.5e-08 34.1 5.1 3.9e-05 23.6 0.0 3.9 4 2 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXX78690.1 - 5.7e-08 32.4 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 KXX78690.1 - 4.5e-05 22.5 116.9 0.02 13.8 18.5 7.1 3 2 4 7 7 7 5 Spc7 kinetochore protein DUF3584 PF12128.8 KXX78690.1 - 0.0001 20.0 39.8 0.0001 20.0 39.8 4.9 2 2 1 5 5 5 2 Protein of unknown function (DUF3584) ATG16 PF08614.11 KXX78690.1 - 0.00016 22.0 109.5 0.12 12.6 8.0 7.3 4 2 1 5 5 5 4 Autophagy protein 16 (ATG16) SbcCD_C PF13558.6 KXX78690.1 - 0.0058 16.8 0.0 0.086 13.1 0.0 3.0 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 KXX78690.1 - 0.84 8.2 97.0 0.18 10.4 25.6 6.4 3 2 2 5 5 5 0 AAA domain ABC_tran PF00005.27 KXX78690.1 - 0.93 10.0 0.0 0.93 10.0 0.0 7.0 4 3 0 4 4 2 0 ABC transporter Baculo_PEP_C PF04513.12 KXX78690.1 - 1.3 9.1 29.1 0.38 10.8 0.1 7.0 5 1 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 KXX78690.1 - 2.2 8.6 6.7 24 5.2 0.0 4.7 4 1 0 4 4 4 0 AAA domain DUF2838 PF10998.8 KXX78691.1 - 8.9e-46 154.7 10.5 8.9e-46 154.7 10.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.7 KXX78691.1 - 0.022 14.9 1.5 0.039 14.1 1.5 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF1640 PF07798.11 KXX78691.1 - 0.16 12.0 0.8 0.57 10.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 KXX78691.1 - 0.27 11.1 3.8 0.52 10.1 3.8 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Glyco_transf_41 PF13844.6 KXX78692.1 - 2.2e-101 339.7 0.0 3.3e-48 164.3 0.0 4.1 3 1 0 4 4 4 3 Glycosyl transferase family 41 TPR_1 PF00515.28 KXX78692.1 - 3.6e-22 77.2 5.1 1.2e-05 24.9 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXX78692.1 - 3.2e-19 67.4 6.7 0.00092 19.2 0.0 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXX78692.1 - 4.9e-14 51.3 2.2 0.0084 16.3 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXX78692.1 - 7.6e-14 51.1 8.2 0.00019 21.1 0.2 6.8 3 2 3 6 6 6 5 TPR repeat TPR_12 PF13424.6 KXX78692.1 - 8.5e-13 48.4 3.3 0.0049 17.1 0.2 4.8 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXX78692.1 - 3.6e-12 45.8 6.8 0.0021 17.9 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXX78692.1 - 1.3e-09 37.7 0.9 0.0051 17.1 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX78692.1 - 4.5e-07 29.4 1.9 0.19 11.8 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX78692.1 - 7e-07 29.5 7.2 0.0087 16.8 0.1 6.2 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX78692.1 - 9.3e-06 26.2 8.0 0.013 16.1 0.4 5.0 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX78692.1 - 6.6e-05 23.3 5.5 0.88 10.1 0.0 4.6 3 2 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXX78692.1 - 0.0098 16.0 0.9 1.1 9.4 0.0 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KXX78692.1 - 0.011 16.1 0.6 0.56 10.6 0.0 2.8 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KXX78692.1 - 0.025 15.2 0.9 17 6.3 0.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX78692.1 - 0.035 14.3 0.4 0.46 10.8 0.4 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L11_N PF03946.14 KXX78693.1 - 5.9e-16 58.1 0.1 9.9e-16 57.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXX78693.1 - 3e-11 43.7 0.1 5.4e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.15 KXX78693.1 - 0.05 13.4 0.0 0.17 11.7 0.0 2.0 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region DNA_pol_lambd_f PF10391.9 KXX78694.1 - 3.9e-21 74.6 0.6 9.3e-21 73.4 0.6 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KXX78694.1 - 3.9e-21 75.4 0.0 6.8e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KXX78694.1 - 3.2e-20 72.0 0.1 7.3e-20 70.9 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KXX78694.1 - 6.7e-13 48.8 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KXX78694.1 - 0.0017 19.0 0.0 0.27 11.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KXX78694.1 - 0.0078 16.5 0.1 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain BRCT_2 PF16589.5 KXX78694.1 - 0.051 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain AadA_C PF18280.1 KXX78694.1 - 0.086 13.0 0.1 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain TFIIE_alpha PF02002.17 KXX78695.1 - 7.2e-17 61.2 0.2 1.3e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KXX78695.1 - 0.0024 17.3 0.2 0.0065 16.0 0.2 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding zinc-ribbons_6 PF07191.12 KXX78695.1 - 0.0078 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 zinc-ribbons SnAC PF14619.6 KXX78695.1 - 0.024 15.2 0.2 0.051 14.2 0.2 1.6 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex zf_UBZ PF18439.1 KXX78695.1 - 0.046 13.3 1.0 3.8 7.2 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Nudix_N_2 PF14803.6 KXX78695.1 - 0.048 13.6 0.6 0.2 11.6 0.3 2.2 2 0 0 2 2 2 0 Nudix N-terminal HscB_4_cys PF18256.1 KXX78695.1 - 0.11 12.4 1.0 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DZR PF12773.7 KXX78695.1 - 0.24 11.5 2.1 4.1 7.5 2.5 2.0 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KXX78695.1 - 0.31 11.2 1.4 1.5 9.0 1.0 2.2 1 1 2 3 3 3 0 Zinc ribbon domain zf-FPG_IleRS PF06827.14 KXX78695.1 - 0.37 10.7 1.6 16 5.5 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS HalOD2 PF18547.1 KXX78695.1 - 0.8 9.7 3.4 5 7.1 3.4 2.1 1 1 0 1 1 1 0 Halobacterial output domain 2 Sec23_trunk PF04811.15 KXX78696.1 - 1.4e-80 270.3 0.0 2e-80 269.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KXX78696.1 - 1.6e-30 105.7 0.2 3.2e-30 104.7 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KXX78696.1 - 2.3e-25 88.4 0.1 6.4e-25 87.0 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KXX78696.1 - 6.3e-16 58.1 6.1 1.2e-15 57.3 6.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXX78696.1 - 2e-14 53.3 0.0 4.7e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXX78696.1 - 0.043 13.2 1.0 0.091 12.2 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MAPEG PF01124.18 KXX78697.1 - 3.6e-22 78.7 2.3 4.3e-22 78.4 2.3 1.1 1 0 0 1 1 1 1 MAPEG family Spo0A_C PF08769.11 KXX78698.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal WD40 PF00400.32 KXX78699.1 - 1.8e-140 452.7 68.5 5.7e-11 42.8 0.2 16.5 16 0 0 16 16 16 16 WD domain, G-beta repeat NACHT_N PF17100.5 KXX78699.1 - 6.9e-73 245.2 0.1 1.1e-72 244.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KXX78699.1 - 5.3e-47 158.1 15.5 0.0077 16.5 0.0 15.1 1 1 14 15 15 15 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX78699.1 - 2e-37 128.9 21.1 0.00065 18.8 0.1 13.3 1 1 12 14 14 14 10 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXX78699.1 - 2.3e-15 56.1 37.5 4.8 7.2 0.1 15.6 16 0 0 16 16 16 3 WD40-like Beta Propeller Repeat NACHT PF05729.12 KXX78699.1 - 2.8e-11 43.6 0.0 6.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.16 KXX78699.1 - 3.3e-10 39.0 14.1 0.026 13.1 0.1 6.2 3 2 4 7 7 7 5 Cytochrome D1 heme domain DUF4784 PF16023.5 KXX78699.1 - 3.4e-07 29.6 3.1 3.3 6.5 0.0 7.3 4 4 6 10 10 10 2 Domain of unknown function (DUF4784) VID27 PF08553.10 KXX78699.1 - 1.1e-06 28.0 8.9 1.5 7.8 0.1 6.1 2 2 3 7 7 7 3 VID27 C-terminal WD40-like domain WD40_like PF17005.5 KXX78699.1 - 1.9e-06 27.4 0.0 4.8 6.4 0.0 6.0 6 1 1 7 7 7 2 WD40-like domain Proteasome_A_N PF10584.9 KXX78699.1 - 5.5e-06 26.0 16.2 31 4.4 0.1 11.2 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature YopE_N PF09020.10 KXX78699.1 - 1.8e-05 25.0 5.3 1.9 8.8 0.0 5.3 2 2 1 5 5 5 2 YopE, N terminal NCOA_u2 PF16665.5 KXX78699.1 - 0.011 16.0 0.5 74 3.7 0.0 4.8 4 1 1 5 5 5 0 Unstructured region on nuclear receptor coactivator protein Invasin_D3 PF09134.10 KXX78699.1 - 0.035 14.4 35.6 1.7 9.0 0.1 9.1 2 2 8 11 11 11 0 Invasin, domain 3 Cuticle_4 PF15955.5 KXX78699.1 - 0.039 14.7 0.4 72 4.2 0.0 4.7 5 0 0 5 5 4 0 Cuticle protein AAA_16 PF13191.6 KXX78699.1 - 0.097 13.1 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KXX78699.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 KXX78701.1 - 0.015 15.4 0.6 0.015 15.4 0.6 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain Bclx_interact PF08945.10 KXX78702.1 - 0.13 12.0 0.1 0.38 10.6 0.1 1.8 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain RhoGAP PF00620.27 KXX78704.1 - 3.2e-45 153.7 0.5 7.4e-45 152.5 0.4 1.6 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KXX78704.1 - 2e-12 47.6 0.0 4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KXX78704.1 - 0.0016 18.9 0.0 0.0044 17.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KXX78704.1 - 0.1 12.9 0.0 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain GOLGA2L5 PF15070.6 KXX78704.1 - 0.31 9.6 5.6 0.066 11.9 0.9 2.0 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Zn_clus PF00172.18 KXX78705.1 - 3.5e-06 27.0 11.0 6.2e-06 26.2 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX78705.1 - 0.00073 18.7 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3915 PF13054.6 KXX78705.1 - 3.5 7.6 11.3 7.8 6.5 11.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) TFIIA PF03153.13 KXX78705.1 - 4.3 7.2 31.4 1.1 9.1 17.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MCM PF00493.23 KXX78706.1 - 5.3e-104 346.2 0.0 9.9e-104 345.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXX78706.1 - 2.8e-31 108.0 0.4 5e-31 107.2 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXX78706.1 - 1.9e-20 73.1 0.2 4.5e-20 71.9 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXX78706.1 - 8.8e-20 71.2 3.5 1.6e-19 70.4 1.5 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXX78706.1 - 1.5e-07 31.0 0.0 1.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXX78706.1 - 1e-06 28.8 0.2 5.9e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KXX78706.1 - 0.0019 18.0 0.1 0.0067 16.2 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KXX78706.1 - 0.022 14.6 0.0 0.085 12.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KXX78706.1 - 0.024 15.3 0.1 0.14 12.8 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 KXX78706.1 - 0.15 11.7 0.0 0.85 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.9 KXX78707.1 - 1.5e-100 336.4 0.0 1.7e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KXX78707.1 - 0.0028 18.1 0.0 0.0053 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXX78708.1 - 3.6e-57 192.4 0.0 3.2e-43 147.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KXX78708.1 - 5.6e-28 97.2 0.0 1.5e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KXX78708.1 - 2.2e-13 49.7 0.1 2.5e-08 33.6 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXX78708.1 - 3e-08 34.3 12.4 0.013 15.8 0.2 5.7 4 2 2 6 6 5 2 AAA ATPase domain AAA_2 PF07724.14 KXX78708.1 - 3.2e-07 30.6 0.0 0.0083 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KXX78708.1 - 3.9e-07 30.1 0.5 0.00051 20.0 0.0 3.6 3 1 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 KXX78708.1 - 9.6e-07 28.5 0.0 4.5e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KXX78708.1 - 4e-05 23.7 0.0 0.066 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KXX78708.1 - 4.7e-05 23.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KXX78708.1 - 6.2e-05 22.8 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXX78708.1 - 6.2e-05 23.3 2.7 0.49 10.7 0.3 4.3 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXX78708.1 - 0.00016 21.8 0.2 0.25 11.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXX78708.1 - 0.00026 21.0 0.1 1.2 9.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KXX78708.1 - 0.00043 19.6 1.0 1.4 8.2 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin Sigma54_activat PF00158.26 KXX78708.1 - 0.0011 18.7 0.0 0.074 12.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 KXX78708.1 - 0.0012 18.1 0.2 1.7 7.7 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain Mg_chelatase PF01078.21 KXX78708.1 - 0.0012 18.2 0.2 0.81 9.0 0.1 2.8 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXX78708.1 - 0.0013 18.5 0.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KXX78708.1 - 0.0018 18.4 0.0 0.14 12.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KXX78708.1 - 0.0019 18.6 0.0 5.2 7.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase TIP49 PF06068.13 KXX78708.1 - 0.0025 17.1 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain ATPase PF06745.13 KXX78708.1 - 0.0031 16.9 0.0 0.83 9.0 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KXX78708.1 - 0.0031 17.1 2.5 1.3 8.6 0.2 3.8 2 2 2 4 4 4 1 AAA domain AAA_18 PF13238.6 KXX78708.1 - 0.0037 17.8 2.1 2.8 8.5 0.0 3.3 3 1 0 3 3 2 1 AAA domain PEX-2N PF09263.10 KXX78708.1 - 0.0076 16.5 0.2 1.1 9.6 0.0 3.1 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal CobU PF02283.16 KXX78708.1 - 0.014 15.0 1.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_19 PF13245.6 KXX78708.1 - 0.016 15.6 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXX78708.1 - 0.019 14.2 0.0 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KXX78708.1 - 0.023 14.6 0.2 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 KXX78708.1 - 0.032 14.7 2.7 2.5 8.5 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 KXX78708.1 - 0.034 13.9 1.4 1.6 8.5 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 KXX78708.1 - 0.035 13.2 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KXX78708.1 - 0.045 13.5 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KXX78708.1 - 0.066 13.4 0.2 20 5.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXX78708.1 - 0.078 13.5 0.0 27 5.3 0.0 2.9 2 0 0 2 2 2 0 ABC transporter APS_kinase PF01583.20 KXX78708.1 - 0.089 12.7 0.9 0.86 9.5 0.0 2.9 3 1 1 4 4 4 0 Adenylylsulphate kinase MGTL PF17059.5 KXX78708.1 - 0.18 11.7 1.5 0.51 10.2 1.5 1.9 1 0 0 1 1 1 0 MgtA leader peptide KAP_NTPase PF07693.14 KXX78708.1 - 0.19 11.0 0.2 8.1 5.6 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain RhoGAP PF00620.27 KXX78709.1 - 7.7e-29 100.5 0.0 1.2e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.12 KXX78710.1 - 7.4e-55 185.2 1.1 8.7e-55 185.0 1.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TRAPP PF04051.16 KXX78711.1 - 0.19 11.4 0.0 0.42 10.3 0.0 1.4 1 1 0 1 1 1 0 Transport protein particle (TRAPP) component FAD_binding_3 PF01494.19 KXX78712.1 - 4.5e-22 78.8 0.0 1.1e-19 70.9 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXX78712.1 - 9.5e-05 21.6 0.6 0.0075 15.4 0.1 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KXX78712.1 - 0.00044 19.9 0.0 0.043 13.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX78712.1 - 0.0031 16.8 0.0 0.016 14.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX78712.1 - 0.0046 17.0 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.10 KXX78712.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase K_oxygenase PF13434.6 KXX78712.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KXX78712.1 - 0.12 11.2 0.0 3.5 6.4 0.0 2.7 2 1 1 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 KXX78712.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Complex1_49kDa PF00346.19 KXX78713.1 - 1.5e-122 407.9 0.0 2.1e-122 407.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KXX78713.1 - 0.0044 16.0 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 KXX78714.1 - 4.9e-27 94.5 0.0 8.9e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXX78714.1 - 1.3e-17 62.9 0.0 1.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Prot_ATP_OB_N PF17758.1 KXX78714.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain ThiF PF00899.21 KXX78715.1 - 6e-66 222.3 0.0 8.3e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KXX78715.1 - 4.1e-32 110.2 0.0 6.6e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 KXX78715.1 - 0.00023 21.7 0.0 0.0021 18.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 KXX78715.1 - 0.00047 20.2 0.4 0.0015 18.6 0.3 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXX78715.1 - 0.017 15.6 0.3 0.04 14.3 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Ecm33 PF12454.8 KXX78715.1 - 0.031 14.4 2.9 0.066 13.4 2.9 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Sacchrp_dh_NADP PF03435.18 KXX78715.1 - 0.082 13.2 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KXX78715.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KXX78715.1 - 0.11 13.1 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GARS_N PF02844.15 KXX78715.1 - 0.12 13.1 0.1 0.85 10.4 0.0 2.3 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain PglD_N PF17836.1 KXX78715.1 - 0.13 12.9 0.2 0.45 11.2 0.1 2.0 2 0 0 2 2 2 0 PglD N-terminal domain Telomere_reg-2 PF10193.9 KXX78716.1 - 1.1e-37 128.8 0.0 4.1e-37 127.0 0.0 2.1 1 0 0 1 1 1 1 Telomere length regulation protein COX17 PF05051.13 KXX78717.1 - 5.6e-21 74.6 7.3 6.6e-21 74.4 7.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) G-patch PF01585.23 KXX78719.1 - 5.6e-06 26.2 0.0 2.6e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXX78719.1 - 0.005 16.9 0.0 0.005 16.9 0.0 3.6 3 1 0 3 3 3 1 G-patch domain Pkinase PF00069.25 KXX78722.1 - 3.3e-53 180.7 0.0 4.6e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78722.1 - 5e-41 140.7 0.0 1e-40 139.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ECH_1 PF00378.20 KXX78722.1 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Haspin_kinase PF12330.8 KXX78722.1 - 0.012 14.5 0.1 0.36 9.7 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXX78722.1 - 0.015 14.1 0.0 0.046 12.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KXX78722.1 - 0.2 11.0 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCM PF00493.23 KXX78723.1 - 1.5e-101 338.2 0.0 3.1e-101 337.2 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXX78723.1 - 5.2e-40 136.2 0.9 9.9e-40 135.3 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXX78723.1 - 9.3e-30 102.9 1.8 2.1e-29 101.8 1.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXX78723.1 - 6.5e-13 49.2 0.0 2e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KXX78723.1 - 1.4e-05 25.1 0.1 6.9e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXX78723.1 - 1.6e-05 24.4 0.0 0.00037 20.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXX78723.1 - 0.0032 17.3 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KXX78723.1 - 0.04 13.7 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 AAA lid domain Oberon_cc PF16312.5 KXX78723.1 - 0.25 11.3 3.3 0.53 10.2 3.3 1.5 1 0 0 1 1 1 0 Coiled-coil region of Oberon Desulfoferrod_N PF06397.12 KXX78723.1 - 0.35 10.5 1.8 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Pil1 PF13805.6 KXX78724.1 - 6.8e-108 360.2 3.3 8e-108 359.9 3.3 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 BAR_3 PF16746.5 KXX78724.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 BAR domain of APPL family Sua5_yciO_yrdC PF01300.18 KXX78725.1 - 3.6e-49 166.7 0.0 6.8e-49 165.8 0.0 1.4 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KXX78725.1 - 2e-26 93.1 0.0 3.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.20 KXX78726.1 - 1.3e-14 54.3 0.3 1.9e-13 50.6 0.3 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain VTC PF09359.10 KXX78727.1 - 3.4e-99 331.7 0.0 5.3e-99 331.1 0.0 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KXX78727.1 - 5.3e-13 49.2 3.3 1.1e-12 48.2 3.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KXX78727.1 - 3.9e-12 46.8 6.6 1.6e-05 25.0 0.1 3.9 2 1 1 4 4 4 2 SPX domain TrmB PF01978.19 KXX78727.1 - 0.0033 17.3 0.3 0.36 10.8 0.1 2.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KXX78727.1 - 0.0073 16.3 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn helix Fe_dep_repress PF01325.19 KXX78727.1 - 0.06 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain FixQ PF05545.11 KXX78727.1 - 0.14 12.2 2.5 0.11 12.5 0.5 1.8 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Ank_2 PF12796.7 KXX78728.1 - 0.0032 18.0 0.0 0.0085 16.7 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ribophorin_I PF04597.14 KXX78729.1 - 1.5e-156 522.0 0.0 1.7e-156 521.8 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I MF_alpha_N PF05436.11 KXX78729.1 - 0.24 11.3 1.1 15 5.6 1.4 2.4 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Hexokinase_2 PF03727.16 KXX78730.1 - 2.5e-79 266.1 0.0 3.6e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXX78730.1 - 9.1e-73 244.4 0.0 1.7e-72 243.5 0.0 1.4 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.21 KXX78730.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain RmlD_sub_bind PF04321.17 KXX78731.1 - 1e-55 188.9 0.0 1.3e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXX78731.1 - 4.8e-23 81.9 0.0 7.3e-23 81.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX78731.1 - 2.1e-11 43.8 0.0 2.4e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXX78731.1 - 4.1e-11 42.5 0.1 2.9e-08 33.2 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KXX78731.1 - 1.1e-10 41.0 0.1 2.8e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXX78731.1 - 3.4e-07 29.7 0.8 0.0002 20.6 0.8 3.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXX78731.1 - 0.0011 18.9 0.3 0.0067 16.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXX78731.1 - 0.0012 18.4 0.5 0.056 13.0 0.3 2.4 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KXX78731.1 - 0.031 13.7 0.2 0.065 12.7 0.2 1.6 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 KXX78731.1 - 0.094 12.6 1.5 0.66 9.9 0.2 2.3 1 1 1 2 2 2 0 KR domain 6PF2K PF01591.18 KXX78732.1 - 8.4e-59 198.6 0.0 1.2e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXX78732.1 - 4e-22 78.9 0.3 3.4e-21 75.8 0.3 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXX78732.1 - 0.0046 17.1 0.0 0.052 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain ZnuA PF01297.17 KXX78732.1 - 0.033 13.6 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic SUIM_assoc PF16619.5 KXX78733.1 - 3.3 7.9 27.9 0.61 10.2 4.3 4.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Acyl-CoA_dh_1 PF00441.24 KXX78735.1 - 1.4e-20 74.0 0.1 3.2e-20 72.9 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXX78735.1 - 4.4e-20 71.7 0.0 7.8e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXX78735.1 - 2.5e-13 50.7 0.0 4.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXX78735.1 - 9e-13 48.7 0.7 2.3e-11 44.1 0.1 2.3 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 KXX78736.1 - 1.1e-15 57.2 1.1 2.3e-15 56.2 1.1 1.6 1 0 0 1 1 1 1 Spo12 family Porin_3 PF01459.22 KXX78737.1 - 1.8e-79 267.0 0.8 2e-79 266.8 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH_1 PF13423.6 KXX78738.1 - 9.5e-38 130.6 0.0 9.9e-37 127.2 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KXX78738.1 - 8.5e-17 61.5 0.0 1.7e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1970 PF09301.10 KXX78738.1 - 0.26 11.6 1.9 8.3 6.7 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) MMR_HSR1_Xtn PF16897.5 KXX78739.1 - 3.4e-35 120.2 1.8 9e-35 118.9 0.6 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KXX78739.1 - 5.1e-21 74.5 0.1 1e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KXX78739.1 - 7.7e-21 74.3 0.0 1.8e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX78739.1 - 1.7e-12 47.1 0.0 2.8e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXX78739.1 - 6.5e-05 23.0 0.2 0.042 13.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KXX78739.1 - 0.07 12.1 0.1 0.17 10.9 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 KXX78739.1 - 0.079 12.0 0.0 0.18 10.9 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain Torus PF16131.5 KXX78740.1 - 1.2e-44 151.4 1.6 1.4e-44 151.3 0.1 1.9 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KXX78740.1 - 2.7e-09 36.7 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KXX78740.1 - 0.00014 21.8 0.6 0.00014 21.8 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KXX78740.1 - 0.00072 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KXX78740.1 - 0.011 15.6 0.7 0.021 14.7 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sulfate_transp PF00916.20 KXX78741.1 - 2.7e-103 345.7 22.3 3.5e-103 345.3 22.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXX78741.1 - 1.5e-08 34.3 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain zf-UBR PF02207.20 KXX78742.1 - 2.6e-19 69.1 16.0 6.6e-19 67.9 16.0 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KXX78742.1 - 0.0014 18.4 0.0 0.0039 16.9 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 KXX78742.1 - 0.019 15.3 0.2 0.019 15.3 0.2 4.1 4 1 1 5 5 5 0 Ring finger domain CAP_N PF01213.19 KXX78742.1 - 1 8.7 3.5 2.3 7.6 3.5 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UCR_UQCRX_QCR9 PF05365.12 KXX78743.1 - 1.4e-27 95.4 1.4 1.6e-27 95.2 1.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like hGDE_N PF14699.6 KXX78743.1 - 0.16 12.1 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Mago-bind PF09282.10 KXX78744.1 - 4.1e-15 55.3 3.1 9.2e-15 54.2 3.1 1.6 1 0 0 1 1 1 1 Mago binding DUF935 PF06074.12 KXX78744.1 - 0.068 11.9 6.3 0.079 11.7 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) RR_TM4-6 PF06459.12 KXX78744.1 - 0.46 10.3 14.2 0.53 10.1 14.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cellulose_synt PF03552.14 KXX78744.1 - 0.69 8.3 2.1 0.86 8.0 2.1 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4407 PF14362.6 KXX78744.1 - 4.9 6.4 8.9 5.3 6.3 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 KXX78744.1 - 7.3 6.6 5.2 8.4 6.4 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_S11 PF00411.19 KXX78745.1 - 1.3e-10 41.7 0.0 2.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 KXX78746.1 - 1.3e-35 122.6 0.0 1.3e-35 122.6 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain PPL5 PF18168.1 KXX78746.1 - 0.25 10.6 13.0 0.53 9.5 13.0 1.5 1 0 0 1 1 1 0 Prim-pol family 5 PPP4R2 PF09184.11 KXX78746.1 - 0.44 10.1 15.4 0.95 9.0 15.4 1.5 1 0 0 1 1 1 0 PPP4R2 NPR3 PF03666.13 KXX78746.1 - 0.95 8.2 14.2 1.6 7.4 14.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 KXX78746.1 - 1.8 7.3 9.4 2.8 6.6 9.4 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 KXX78746.1 - 2.3 7.1 8.0 4 6.3 8.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S64 PF08192.11 KXX78746.1 - 5.8 5.3 12.3 8.2 4.8 12.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 KXX78746.1 - 8 5.4 11.3 15 4.5 11.3 1.5 1 0 0 1 1 1 0 Solute carrier family 12 DUF1768 PF08719.11 KXX78747.1 - 2.7e-43 148.0 0.0 1.3e-42 145.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) BCS1_N PF08740.11 KXX78748.1 - 1.2e-40 139.5 0.1 1.7e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXX78748.1 - 1.7e-20 73.8 0.0 2.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX78748.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX78748.1 - 7.5e-05 23.2 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXX78748.1 - 0.00016 21.7 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX78748.1 - 0.00041 20.6 0.0 0.00089 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXX78748.1 - 0.00042 19.9 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KXX78748.1 - 0.0036 16.5 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXX78748.1 - 0.0054 17.3 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXX78748.1 - 0.0069 16.1 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXX78748.1 - 0.015 14.9 0.1 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXX78748.1 - 0.019 15.4 0.1 2 8.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 KXX78748.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXX78748.1 - 0.034 14.1 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KXX78748.1 - 0.034 14.3 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KXX78748.1 - 0.039 14.4 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KXX78748.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXX78748.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KXX78748.1 - 0.06 13.9 0.0 0.15 12.6 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA_3 PF07726.11 KXX78748.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXX78748.1 - 0.12 12.7 1.3 1.7 9.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_6 PF12774.7 KXX78748.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_21 PF13304.6 KXX78748.1 - 0.13 12.0 0.3 0.75 9.5 0.0 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 KXX78748.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PPV_E1_C PF00519.17 KXX78748.1 - 0.16 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase IstB_IS21 PF01695.17 KXX78748.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KXX78748.1 - 0.28 10.3 0.0 0.43 9.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain polyprenyl_synt PF00348.17 KXX78749.1 - 1.7e-90 302.6 0.0 2.1e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase ANAPC8 PF04049.13 KXX78750.1 - 6.2e-56 188.3 0.3 1.3e-55 187.3 0.0 1.7 2 0 0 2 2 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KXX78750.1 - 9.6e-21 72.2 12.5 2.5e-05 24.1 0.0 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXX78750.1 - 1.5e-17 62.6 9.5 0.00042 20.0 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX78750.1 - 8e-10 38.1 30.0 0.24 11.6 0.0 10.0 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX78750.1 - 2.1e-08 34.3 20.9 0.0012 19.5 0.1 9.0 7 3 2 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXX78750.1 - 6.3e-07 29.0 2.8 6.9e-06 25.6 0.4 3.2 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 KXX78750.1 - 5.5e-06 26.9 13.6 6.3e-06 26.7 1.2 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX78750.1 - 0.00028 20.7 11.0 0.083 13.0 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXX78750.1 - 0.0014 18.9 0.1 2.4 8.7 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX78750.1 - 0.0014 18.8 12.2 0.07 13.4 0.6 4.9 4 1 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KXX78750.1 - 0.0051 16.9 3.0 0.077 13.1 0.2 3.0 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) ChAPs PF09295.10 KXX78750.1 - 0.011 14.8 0.1 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 KXX78750.1 - 0.021 14.9 14.1 0.88 9.8 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4398 PF14346.6 KXX78750.1 - 0.098 13.3 0.7 0.43 11.2 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) TPR_6 PF13174.6 KXX78750.1 - 0.13 13.0 14.7 2.6 8.9 0.4 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXX78750.1 - 0.13 12.5 28.6 0.67 10.3 0.1 7.4 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXX78750.1 - 0.61 10.6 0.1 0.61 10.6 0.1 6.7 5 1 2 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX78750.1 - 6.3 6.8 10.7 17 5.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps54 PF07928.12 KXX78752.1 - 4.5e-52 176.0 0.2 1.5e-51 174.4 0.2 2.0 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KXX78752.1 - 1.9e-06 27.4 0.2 5e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXX78752.1 - 7.7e-05 22.6 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 KXX78752.1 - 0.019 14.9 0.5 0.57 10.1 0.1 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 KXX78752.1 - 0.095 12.8 1.3 0.31 11.1 0.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MCM PF00493.23 KXX78753.1 - 2.2e-105 350.7 0.1 9.9e-105 348.6 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXX78753.1 - 1.9e-36 124.7 0.1 3.5e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXX78753.1 - 3.9e-28 97.7 1.0 9.2e-28 96.5 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXX78753.1 - 8.6e-14 52.0 0.3 2.1e-13 50.8 0.3 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXX78753.1 - 7.5e-07 28.7 0.0 0.00021 20.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXX78753.1 - 1.1e-05 25.4 0.0 4.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXX78753.1 - 0.00022 21.1 0.0 0.00097 19.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXX78753.1 - 0.062 13.0 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KXX78753.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_RNApol_7kD PF03604.13 KXX78753.1 - 0.15 11.7 1.8 9.6 6.0 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Mg_chelatase_C PF13335.6 KXX78753.1 - 0.17 12.6 1.7 0.5 11.0 0.9 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal HGTP_anticodon2 PF12745.7 KXX78754.1 - 1.1e-89 300.4 4.3 1.5e-89 300.0 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KXX78754.1 - 1.2e-75 254.3 0.0 1.1e-36 126.5 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78754.1 - 5.1e-46 157.1 0.0 2.6e-20 72.8 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KXX78754.1 - 8.5e-18 64.7 1.1 2.3e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 KXX78754.1 - 2e-11 44.2 0.0 6.3e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 KXX78754.1 - 1.2e-05 24.7 0.0 3.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXX78754.1 - 5.7e-05 23.2 0.9 0.09 12.7 0.0 2.9 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXX78754.1 - 0.00048 19.0 3.8 0.15 10.8 0.0 3.1 3 0 0 3 3 3 2 Fungal protein kinase zf-C4H2 PF10146.9 KXX78754.1 - 0.013 15.9 4.5 0.036 14.4 4.5 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein FTA2 PF13095.6 KXX78754.1 - 0.038 13.6 0.2 1.5 8.4 0.0 3.1 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Cut12 PF11500.8 KXX78755.1 - 2.7e-44 150.6 14.6 2.7e-44 150.6 14.6 4.6 5 2 1 6 6 6 1 Spindle pole body formation-associated protein UreF PF01730.16 KXX78755.1 - 6e-21 75.4 0.5 6e-21 75.4 0.5 2.4 2 0 0 2 2 2 1 UreF UPF0242 PF06785.11 KXX78755.1 - 0.00012 22.2 15.5 0.00012 22.2 15.5 2.8 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Bacillus_HBL PF05791.11 KXX78755.1 - 7.7 6.3 10.6 0.36 10.6 3.4 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UBA_4 PF14555.6 KXX78756.1 - 0.034 14.0 0.2 0.1 12.4 0.2 1.9 1 0 0 1 1 1 0 UBA-like domain FtsX_ECD PF18075.1 KXX78756.1 - 0.19 12.4 1.0 4.9 7.9 0.2 2.7 2 0 0 2 2 2 0 FtsX extracellular domain UIM PF02809.20 KXX78756.1 - 0.96 9.5 10.4 0.082 12.9 3.7 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif ABC_tran_CTD PF16326.5 KXX78756.1 - 1 9.7 5.8 0.14 12.4 0.7 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain UQ_con PF00179.26 KXX78757.1 - 4.3e-35 120.4 0.0 5.5e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF410 PF04190.13 KXX78759.1 - 2.8e-91 305.8 0.0 3.8e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) GMC_oxred_C PF05199.13 KXX78760.1 - 1.6e-10 41.6 0.2 7.1e-09 36.3 0.1 2.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXX78760.1 - 8.4e-07 28.6 0.3 6e-06 25.9 0.3 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX78760.1 - 8.9e-05 21.7 0.3 0.00014 21.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXX78760.1 - 0.00074 19.0 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX78760.1 - 0.0052 16.1 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX78760.1 - 0.013 15.7 0.2 0.04 14.2 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX78760.1 - 0.022 13.8 0.0 0.048 12.7 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KXX78760.1 - 0.07 12.7 0.7 0.57 9.7 0.1 2.7 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXX78760.1 - 0.097 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXX78760.1 - 0.11 11.2 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KXX78760.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF900 PF05990.12 KXX78760.1 - 0.16 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) GhoS PF11080.8 KXX78760.1 - 0.19 11.7 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease GhoS DNA_pol_B PF00136.21 KXX78761.1 - 6.1e-151 503.2 1.9 8.6e-151 502.7 1.9 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXX78761.1 - 4.9e-80 269.2 0.8 9.3e-80 268.3 0.3 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXX78761.1 - 3.7e-15 56.1 4.1 9.6e-15 54.8 4.1 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KXX78761.1 - 0.00014 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 KXX78761.1 - 0.0017 17.3 0.1 0.051 12.4 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF2614 PF11023.8 KXX78761.1 - 0.16 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain C1_1 PF00130.22 KXX78761.1 - 2.9 7.8 9.2 1.2 9.1 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RabGAP-TBC PF00566.18 KXX78762.1 - 3.4e-32 111.8 0.0 1.4e-26 93.5 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HlyIII PF03006.20 KXX78763.1 - 2.2e-63 214.0 17.9 2.8e-63 213.7 17.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related An_peroxidase PF03098.15 KXX78763.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase LIDHydrolase PF10230.9 KXX78764.1 - 6.1e-51 173.5 0.0 5e-49 167.2 0.0 2.0 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KXX78764.1 - 0.00012 22.8 0.2 0.00015 22.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXX78764.1 - 0.015 15.0 0.1 0.03 14.0 0.1 1.4 1 1 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KXX78764.1 - 0.044 13.0 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FHA PF00498.26 KXX78764.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 FHA domain Abhydrolase_1 PF00561.20 KXX78764.1 - 0.12 11.9 0.1 0.38 10.4 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Spherulin4 PF12138.8 KXX78766.1 - 5.9e-12 45.7 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Spherulation-specific family 4 CVNH PF08881.10 KXX78767.1 - 1.6e-12 48.0 0.1 5.7e-12 46.2 0.1 1.7 1 1 0 1 1 1 1 CVNH domain DUF1282 PF06930.12 KXX78769.1 - 0.0078 16.0 1.3 0.012 15.3 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) T5orf172 PF10544.9 KXX78771.1 - 1e-25 90.3 1.2 2.7e-25 88.9 0.8 1.9 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KXX78771.1 - 1.6e-24 86.3 0.4 3.2e-24 85.4 0.4 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Ribonuclease PF00545.20 KXX78772.1 - 5.1e-08 33.5 0.0 7.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Swi5 PF07061.11 KXX78773.1 - 2.7e-18 65.8 0.1 6.5e-18 64.6 0.1 1.7 1 0 0 1 1 1 1 Swi5 DCP1 PF06058.13 KXX78774.1 - 1.5e-30 105.5 0.0 2.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family TPR_9 PF13371.6 KXX78774.1 - 0.1 12.8 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 KXX78775.1 - 8.7e-18 64.9 0.0 1.4e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXX78775.1 - 2.8e-06 26.5 0.0 7e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXX78775.1 - 0.014 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sugar_tr PF00083.24 KXX78776.1 - 6.9e-74 249.3 17.0 7.9e-74 249.1 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX78776.1 - 6.3e-16 58.2 31.3 6.3e-16 58.2 31.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MerC PF03203.14 KXX78776.1 - 9.9 6.7 10.7 1.9 8.9 0.5 2.8 2 1 0 2 2 2 0 MerC mercury resistance protein Pyr_redox_2 PF07992.14 KXX78777.1 - 6.8e-06 25.5 0.0 0.00012 21.5 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXX78777.1 - 2.2e-05 23.1 0.0 4.3e-05 22.1 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXX78777.1 - 0.00023 21.3 0.1 0.0029 17.8 0.2 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KXX78777.1 - 0.0038 17.3 0.0 0.057 13.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXX78777.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KXX78777.1 - 0.019 14.2 0.5 0.2 10.9 0.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXX78777.1 - 0.027 13.6 0.0 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cyclase PF04199.13 KXX78778.1 - 1.6e-15 57.5 0.2 2.3e-15 57.0 0.2 1.2 1 0 0 1 1 1 1 Putative cyclase NACHT PF05729.12 KXX78780.1 - 3.7e-18 66.0 0.1 6.8e-18 65.1 0.1 1.5 1 1 0 1 1 1 1 NACHT domain SesA PF17107.5 KXX78780.1 - 2.9e-10 40.4 0.0 2.7e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_19 PF13245.6 KXX78780.1 - 0.0092 16.3 0.1 0.014 15.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX78780.1 - 0.0095 16.3 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX78780.1 - 0.028 14.7 0.1 0.073 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXX78780.1 - 0.031 14.0 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KXX78780.1 - 0.034 13.0 0.0 0.071 12.0 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase DUF2075 PF09848.9 KXX78780.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Lebercilin PF15619.6 KXX78781.1 - 0.011 15.4 12.6 0.011 15.4 12.6 3.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 KXX78781.1 - 0.028 12.0 41.0 0.038 11.5 41.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HOOK PF05622.12 KXX78781.1 - 0.041 12.0 42.8 0.067 11.3 42.8 1.2 1 0 0 1 1 1 0 HOOK protein DUF4250 PF14056.6 KXX78781.1 - 2.5 8.1 18.4 1.4 8.9 0.4 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4250) DUF3618 PF12277.8 KXX78781.1 - 6.8 7.0 13.4 2.1 8.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) SurA_N PF09312.11 KXX78781.1 - 9 6.4 13.2 0.62 10.2 0.7 3.2 3 0 0 3 3 3 0 SurA N-terminal domain Pectate_lyase_3 PF12708.7 KXX78784.1 - 6.1e-73 245.2 17.6 6.3e-63 212.5 4.9 3.6 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXX78784.1 - 0.0013 18.3 2.2 0.018 14.7 0.4 2.7 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Varsurf_PPLC PF03490.13 KXX78784.1 - 0.0054 16.6 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C 4HBT PF03061.22 KXX78785.1 - 9.8e-15 54.7 0.8 1.8e-14 53.8 0.8 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXX78785.1 - 0.00048 20.4 0.2 0.00073 19.9 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Ligase_CoA PF00549.19 KXX78786.1 - 1.9e-23 83.0 0.3 3e-23 82.3 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KXX78786.1 - 2.2e-15 57.1 7.3 1.4e-14 54.6 1.3 3.1 2 1 1 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.6 KXX78786.1 - 1e-09 38.3 0.1 1.8e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KXX78786.1 - 0.00053 20.5 0.1 0.0018 18.7 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain UQ_con PF00179.26 KXX78787.1 - 1e-39 135.4 0.0 1.3e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KXX78787.1 - 3.2e-06 26.8 0.1 5.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KXX78787.1 - 0.00023 20.9 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXX78787.1 - 0.035 14.0 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 UEV domain DUF1421 PF07223.11 KXX78787.1 - 0.046 13.6 0.8 0.12 12.2 0.3 1.8 2 0 0 2 2 2 0 UBA-like domain (DUF1421) UBA PF00627.31 KXX78787.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Sod_Fe_C PF02777.18 KXX78788.1 - 3.8e-35 120.1 0.1 8.1e-35 119.1 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXX78788.1 - 1.2e-33 115.5 4.7 1.2e-33 115.5 4.7 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain BAG PF02179.16 KXX78790.1 - 1.7e-20 73.2 0.1 2.7e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KXX78790.1 - 0.00015 21.5 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 KXX78790.1 - 0.17 11.9 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Glutaredoxin PF00462.24 KXX78791.1 - 1.8e-19 69.7 0.0 4.2e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KXX78791.1 - 0.0009 19.1 0.0 0.00099 19.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KXX78791.1 - 0.016 15.6 0.1 0.025 15.0 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 KXX78791.1 - 0.027 14.9 0.0 0.037 14.4 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 KXX78791.1 - 0.077 13.4 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF953 PF06110.11 KXX78791.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DUF4942 PF13708.6 KXX78791.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) AhpC-TSA PF00578.21 KXX78791.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DSBA PF01323.20 KXX78791.1 - 0.17 11.6 0.3 0.48 10.2 0.1 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain AAA PF00004.29 KXX78792.1 - 4.1e-41 140.5 0.0 7.7e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXX78792.1 - 7.8e-12 45.0 0.2 1.7e-11 43.9 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXX78792.1 - 9.2e-11 41.4 0.9 1.7e-10 40.5 0.9 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KXX78792.1 - 2.3e-06 27.8 0.0 4.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXX78792.1 - 5.6e-06 26.7 0.2 0.0058 16.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXX78792.1 - 1.1e-05 24.7 0.0 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXX78792.1 - 8.2e-05 22.6 0.1 0.00028 20.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXX78792.1 - 0.00022 21.6 0.2 0.0028 18.1 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXX78792.1 - 0.00033 20.4 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXX78792.1 - 0.00065 20.2 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KXX78792.1 - 0.0021 17.7 0.8 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 KXX78792.1 - 0.0026 18.0 0.3 0.008 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXX78792.1 - 0.0043 17.2 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXX78792.1 - 0.017 15.0 0.2 0.62 10.0 0.1 2.5 2 1 1 3 3 2 0 NACHT domain AAA_14 PF13173.6 KXX78792.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXX78792.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KXX78792.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXX78792.1 - 0.02 14.3 1.8 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 KXX78792.1 - 0.022 13.9 0.2 0.07 12.3 0.1 1.7 1 1 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KXX78792.1 - 0.042 13.2 0.1 0.51 9.7 0.1 2.2 1 1 0 2 2 2 0 KaiC RNA_helicase PF00910.22 KXX78792.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXX78792.1 - 0.061 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KXX78792.1 - 0.068 12.4 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KXX78792.1 - 0.078 12.5 1.5 0.57 9.7 0.4 2.5 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXX78792.1 - 0.086 12.5 0.3 0.29 10.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXX78792.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ribosomal_L13 PF00572.18 KXX78793.1 - 1.2e-11 44.9 0.0 1.2e-09 38.4 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 Chalcone_2 PF16035.5 KXX78794.1 - 1.6e-76 256.7 0.0 2.5e-76 256.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KXX78794.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Chalcone isomerase-like LRR_6 PF13516.6 KXX78795.1 - 6.4e-16 57.0 24.1 0.34 11.1 0.0 12.0 12 0 0 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.7 KXX78795.1 - 7.2e-13 48.5 14.2 0.0068 16.8 0.3 7.5 6 1 2 8 8 8 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXX78795.1 - 2e-12 46.8 4.6 1.3e-11 44.2 0.8 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXX78795.1 - 0.00025 20.8 0.6 0.00025 20.8 0.6 2.2 2 0 0 2 2 2 1 F-box domain Recep_L_domain PF01030.24 KXX78795.1 - 0.11 12.6 1.3 52 4.0 0.1 3.9 2 1 2 4 4 4 0 Receptor L domain Acetyltransf_7 PF13508.7 KXX78797.1 - 2.2e-07 31.2 0.7 9e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX78797.1 - 1.6e-05 25.1 0.4 4.1e-05 23.8 0.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX78797.1 - 0.00092 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX78797.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 KXX78797.1 - 0.14 12.9 0.2 0.25 12.0 0.2 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 KXX78799.1 - 3e-42 144.9 0.0 4.9e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX78799.1 - 1.7e-37 129.5 0.0 3.2e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX78799.1 - 6e-21 74.3 0.2 1.1e-20 73.5 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pex24p PF06398.11 KXX78800.1 - 9.6e-100 334.1 0.0 1.2e-99 333.8 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ank_2 PF12796.7 KXX78801.1 - 6.1e-64 212.6 0.0 1e-19 70.9 0.0 5.3 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX78801.1 - 7.1e-59 195.5 3.0 1.2e-10 41.6 0.0 7.2 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX78801.1 - 1.5e-42 138.7 0.0 0.00017 21.7 0.0 9.6 10 0 0 10 10 9 6 Ankyrin repeat Ank PF00023.30 KXX78801.1 - 4.4e-40 134.4 0.0 0.00026 21.3 0.0 8.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KXX78801.1 - 5.3e-30 103.1 5.3 1.6e-06 28.3 0.0 7.7 2 1 6 8 8 7 6 Ankyrin repeats (many copies) NACHT PF05729.12 KXX78801.1 - 3.9e-06 26.9 0.1 1.1e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX78801.1 - 0.00014 22.3 0.0 0.00038 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 KXX78801.1 - 0.00076 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_30 PF13604.6 KXX78801.1 - 0.0044 16.8 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXX78801.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cthe_2159 PF14262.6 KXX78801.1 - 0.017 14.5 0.0 1.1 8.5 0.0 2.8 1 1 0 1 1 1 0 Carbohydrate-binding domain-containing protein Cthe_2159 PGAP1 PF07819.13 KXX78801.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein NB-ARC PF00931.22 KXX78801.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KXX78801.1 - 0.15 11.8 0.0 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXX78801.1 - 0.22 10.8 0.0 0.51 9.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin VWA_3_C PF18571.1 KXX78801.1 - 0.62 10.0 9.0 1.6e+02 2.3 0.0 6.1 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain LegC3_N PF18654.1 KXX78806.1 - 2 7.6 6.6 1.7 7.8 0.1 2.3 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain DUF29 PF01724.16 KXX78806.1 - 2.6 8.3 5.8 14 5.9 0.6 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF29 FAM184 PF15665.5 KXX78806.1 - 3.5 7.3 5.8 39 3.9 1.1 3.2 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B Vint PF14623.6 KXX78807.1 - 1.6e-54 184.2 0.0 2.6e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KXX78807.1 - 4.1e-28 97.3 0.0 6.4e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KXX78807.1 - 2.5e-13 50.7 0.0 3.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXX78807.1 - 4.7e-11 43.3 0.0 2.7e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXX78807.1 - 7e-10 39.1 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF966 PF06136.13 KXX78809.1 - 2.9 7.5 6.0 3.6 7.2 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3818 PF12825.7 KXX78810.1 - 1.9e-46 158.7 0.0 1.3e-25 90.2 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXX78810.1 - 4.1e-39 133.5 0.0 8.6e-39 132.5 0.0 1.6 1 0 0 1 1 1 1 PX-associated UBA_2 PF08587.11 KXX78810.1 - 0.021 14.9 0.5 0.068 13.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Cu-oxidase_3 PF07732.15 KXX78811.1 - 3.3e-26 91.6 0.0 3.9e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXX78811.1 - 0.00091 19.0 0.1 0.0039 16.9 0.1 1.8 1 1 0 1 1 1 1 Multicopper oxidase MACPF PF01823.19 KXX78813.1 - 1.2e-06 28.8 0.6 1.7e-06 28.3 0.6 1.2 1 0 0 1 1 1 1 MAC/Perforin domain Pro_Al_protease PF02983.14 KXX78813.1 - 0.15 12.1 0.0 0.78 9.8 0.0 2.1 2 0 0 2 2 2 0 Alpha-lytic protease prodomain DUF1664 PF07889.12 KXX78814.1 - 0.0029 17.6 1.1 0.0054 16.8 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Lant_dehydr_C PF14028.6 KXX78814.1 - 0.021 14.4 1.1 0.035 13.7 1.1 1.3 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term CRR7 PF12095.8 KXX78814.1 - 0.022 15.2 1.1 0.23 11.9 0.0 2.6 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF961 PF06125.11 KXX78814.1 - 0.033 14.6 0.2 0.062 13.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) Baculo_PEP_C PF04513.12 KXX78814.1 - 0.097 12.7 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 KXX78814.1 - 0.12 12.8 1.5 0.23 12.0 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF2120 PF09893.9 KXX78814.1 - 0.13 12.3 0.8 0.36 10.9 0.7 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Tropomyosin PF00261.20 KXX78814.1 - 0.16 11.3 4.6 0.31 10.4 4.6 1.5 1 1 0 1 1 1 0 Tropomyosin Allexi_40kDa PF05549.11 KXX78814.1 - 0.18 11.3 1.1 0.26 10.8 1.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Phasin PF05597.11 KXX78814.1 - 0.27 11.2 1.6 0.43 10.6 1.6 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tropomyosin_1 PF12718.7 KXX78814.1 - 0.83 9.8 5.0 1.4 9.1 5.0 1.3 1 0 0 1 1 1 0 Tropomyosin like Noelin-1 PF12308.8 KXX78814.1 - 1.7 8.7 4.4 1 9.4 0.7 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein Thiolase_N PF00108.23 KXX78816.1 - 7.2e-68 228.7 2.0 9.4e-68 228.4 2.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX78816.1 - 2.1e-40 137.2 1.5 5.7e-40 135.8 1.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain YabA PF06156.13 KXX78820.1 - 0.28 11.8 2.7 0.71 10.5 2.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA BshC PF10079.9 KXX78820.1 - 0.69 8.6 7.6 1 8.0 7.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC TIM21 PF08294.11 KXX78822.1 - 2.3e-46 157.3 0.1 2.9e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KXX78822.1 - 2.1e-06 27.5 0.0 5.5e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ADH_N PF08240.12 KXX78823.1 - 4.4e-29 100.5 0.3 4.4e-29 100.5 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX78823.1 - 1.8e-12 47.4 0.3 3.8e-12 46.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXX78823.1 - 2e-08 34.0 0.4 0.0029 17.1 0.2 2.5 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXX78823.1 - 0.022 14.0 0.5 0.044 13.1 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.21 KXX78824.1 - 6e-35 120.9 0.0 1.8e-24 86.5 0.0 3.0 1 1 2 3 3 3 3 Aldo/keto reductase family YflT PF11181.8 KXX78824.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.8 1 0 0 1 1 1 0 Heat induced stress protein YflT Lipase_3 PF01764.25 KXX78825.1 - 3e-15 56.3 0.0 1.8e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Cupin_6 PF12852.7 KXX78825.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Cupin Acetyltransf_1 PF00583.25 KXX78826.1 - 5.8e-13 49.1 0.1 7.5e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX78826.1 - 8.5e-08 32.5 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX78826.1 - 2.1e-07 30.9 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.6 KXX78827.1 - 5e-58 196.4 0.1 6.5e-58 196.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX78827.1 - 1.2e-52 178.2 0.3 2.4e-52 177.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXX78827.1 - 6.2e-14 52.3 0.5 1.1e-13 51.5 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXX78827.1 - 5.9e-07 29.2 0.0 7.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXX78827.1 - 0.0019 17.4 0.2 0.0038 16.4 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain PALP PF00291.25 KXX78827.1 - 0.068 12.6 0.3 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GDP_Man_Dehyd PF16363.5 KXX78827.1 - 0.083 12.3 0.1 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1815 PF08844.10 KXX78827.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) NmrA PF05368.13 KXX78827.1 - 1.5 8.4 3.8 0.66 9.5 0.5 2.1 2 1 1 3 3 3 0 NmrA-like family DUF1100 PF06500.11 KXX78828.1 - 5.4e-12 45.2 0.0 6.8e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KXX78828.1 - 1.3e-05 24.7 0.1 3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXX78828.1 - 0.0003 20.5 0.0 0.0029 17.3 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 KXX78828.1 - 0.00032 20.4 0.3 0.00051 19.7 0.3 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 KXX78828.1 - 0.0036 16.8 0.0 0.01 15.3 0.0 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KXX78828.1 - 0.037 14.6 1.3 0.059 14.0 0.2 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX78828.1 - 0.043 13.1 0.0 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 KXX78828.1 - 0.097 12.2 0.0 2.1 7.9 0.0 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family ArfGap PF01412.18 KXX78831.1 - 2.7e-33 114.5 0.7 4.8e-33 113.7 0.2 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.22 KXX78832.1 - 1.6e-71 240.8 0.0 2.4e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KXX78832.1 - 7.6e-36 123.0 0.0 2.3e-35 121.5 0.0 1.8 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PEP_mutase PF13714.6 KXX78832.1 - 0.072 12.5 0.4 0.26 10.7 0.2 1.9 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Mst1_SARAH PF11629.8 KXX78833.1 - 0.2 11.8 0.3 0.32 11.1 0.3 1.3 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 NMO PF03060.15 KXX78836.1 - 7.6e-57 193.2 0.1 1.2e-56 192.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXX78836.1 - 3.9e-11 42.6 0.3 7.5e-11 41.6 0.3 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXX78836.1 - 1.3e-06 27.7 1.2 1.9e-06 27.2 1.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXX78836.1 - 0.0021 17.3 0.5 0.0045 16.2 0.5 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NanE PF04131.14 KXX78836.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase NDT80_PhoG PF05224.12 KXX78837.1 - 2.2e-43 148.6 0.0 4.9e-43 147.5 0.0 1.6 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family AfaD PF05775.12 KXX78837.1 - 0.099 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein MscL PF01741.18 KXX78838.1 - 2.9e-17 63.1 0.0 3.6e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.15 KXX78838.1 - 7.3e-05 22.7 1.6 0.00011 22.2 1.6 1.3 1 0 0 1 1 1 1 BED zinc finger C1_1 PF00130.22 KXX78838.1 - 0.036 13.9 1.3 0.056 13.3 1.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cwf_Cwc_15 PF04889.12 KXX78838.1 - 2.4 7.8 8.0 3.3 7.4 8.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SUR7 PF06687.12 KXX78839.1 - 9.6e-13 48.2 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family YjcB PF15940.5 KXX78839.1 - 0.02 15.0 0.5 0.043 14.0 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function SNARE PF05739.19 KXX78840.1 - 9.9e-14 51.1 0.7 4.3e-13 49.1 0.1 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KXX78840.1 - 0.00032 20.4 0.4 0.00032 20.4 0.4 2.9 2 1 1 3 3 3 1 Syntaxin KxDL PF10241.9 KXX78840.1 - 0.0023 18.2 1.6 3 8.2 0.0 3.1 3 1 0 3 3 3 2 Uncharacterized conserved protein Snapin_Pallidin PF14712.6 KXX78840.1 - 0.015 15.7 0.9 3.4 8.2 0.0 2.7 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin-18_N PF10496.9 KXX78840.1 - 0.024 14.9 0.7 0.084 13.1 0.1 2.1 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1664 PF07889.12 KXX78840.1 - 0.029 14.4 1.3 0.95 9.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Trimer_CC PF08954.11 KXX78840.1 - 0.031 13.8 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 Trimerisation motif Peripla_BP_2 PF01497.18 KXX78840.1 - 0.032 13.8 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Syntaxin-5_N PF11416.8 KXX78840.1 - 0.06 12.6 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain MCPsignal PF00015.21 KXX78840.1 - 0.083 12.7 6.3 0.08 12.7 2.2 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 KXX78840.1 - 0.17 12.4 3.2 24 5.5 0.0 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Muted PF14942.6 KXX78840.1 - 0.2 12.0 8.8 0.67 10.3 0.6 2.5 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Prominin PF05478.11 KXX78840.1 - 0.44 8.4 5.5 1.2 7.0 1.3 2.3 2 1 0 2 2 2 0 Prominin DUF16 PF01519.16 KXX78840.1 - 0.78 10.3 5.2 0.66 10.5 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 NMT PF01233.19 KXX78841.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain SKG6 PF08693.10 KXX78843.1 - 0.073 12.5 1.6 0.14 11.5 1.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4381 PF14316.6 KXX78843.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TFIIA PF03153.13 KXX78843.1 - 6.7 6.6 7.5 9.1 6.2 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ARS2 PF04959.13 KXX78843.1 - 6.8 7.0 6.8 12 6.2 6.8 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Glyco_hydro_43 PF04616.14 KXX78844.1 - 5.7e-28 98.1 4.9 2.2e-26 92.9 4.9 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Response_reg PF00072.24 KXX78845.1 - 1.7e-19 70.1 0.0 1.2e-13 51.2 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DUF87 PF01935.17 KXX78846.1 - 0.0012 19.0 0.1 0.016 15.3 0.1 2.1 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 KXX78846.1 - 0.004 17.5 0.0 0.52 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX78846.1 - 0.022 15.0 0.1 0.67 10.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KXX78846.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.12 KXX78846.1 - 0.097 12.3 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.12 KXX78846.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF2052 PF09747.9 KXX78847.1 - 8.6e-28 97.8 16.3 6.2e-26 91.8 16.3 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Y_phosphatase3 PF13350.6 KXX78849.1 - 9e-58 196.0 0.0 1e-57 195.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXX78849.1 - 2.4e-05 24.0 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KXX78849.1 - 0.00045 19.8 0.0 0.00073 19.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXX78849.1 - 0.024 14.4 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain G2BR PF18442.1 KXX78849.1 - 0.039 13.6 0.5 3.2 7.5 0.1 2.5 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) Myotub-related PF06602.14 KXX78849.1 - 0.2 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Bot1p PF12298.8 KXX78850.1 - 7e-54 182.6 4.2 1.1e-53 181.9 4.2 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Fungus-induced PF10917.8 KXX78850.1 - 0.13 12.5 0.4 0.27 11.6 0.4 1.4 1 0 0 1 1 1 0 Fungus-induced protein Bromodomain PF00439.25 KXX78851.1 - 3.4e-18 65.5 0.1 6.8e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 KXX78851.1 - 0.0029 17.8 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CHCH PF06747.13 KXX78851.1 - 0.25 11.5 1.8 8.9 6.6 1.1 2.3 2 0 0 2 2 2 0 CHCH domain DUF1476 PF07345.11 KXX78851.1 - 0.27 11.6 1.4 23 5.4 0.0 2.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Pectate_lyase_3 PF12708.7 KXX78852.1 - 1e-98 329.5 6.0 1.8e-86 289.5 0.2 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXX78852.1 - 1.1e-07 31.4 2.3 0.013 15.2 0.2 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.13 KXX78852.1 - 0.027 13.8 0.1 0.059 12.6 0.1 1.5 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) HET PF06985.11 KXX78853.1 - 1e-28 100.5 0.0 2e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 KXX78853.1 - 0.0079 16.0 13.9 0.0079 16.0 13.9 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type Pept_S41_N PF18294.1 KXX78853.1 - 0.09 12.8 0.1 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain CTD_bind PF04818.13 KXX78854.1 - 2.4e-18 66.7 0.0 6.4e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DGCR6 PF07324.11 KXX78854.1 - 0.00059 19.5 0.6 0.041 13.5 0.3 2.2 2 0 0 2 2 2 2 DiGeorge syndrome critical region 6 (DGCR6) protein CREPT PF16566.5 KXX78854.1 - 0.0059 16.8 1.3 0.014 15.6 1.3 1.7 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour MCD_N PF17408.2 KXX78854.1 - 0.044 13.9 1.1 0.1 12.7 1.1 1.7 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain Spc7 PF08317.11 KXX78854.1 - 0.14 11.0 3.8 0.26 10.1 3.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AA_kinase PF00696.28 KXX78855.1 - 4.4e-37 128.0 1.3 9.2e-37 126.9 0.1 1.9 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 KXX78855.1 - 6.7e-15 54.6 1.9 6.9e-09 35.3 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KXX78855.1 - 8e-14 51.2 3.4 1.8e-10 40.5 0.2 2.5 2 0 0 2 2 2 2 ACT domain SHNi-TPR PF10516.9 KXX78855.1 - 0.16 11.4 0.1 0.41 10.1 0.1 1.7 1 0 0 1 1 1 0 SHNi-TPR ABC_membrane PF00664.23 KXX78856.1 - 2.3e-52 178.4 9.6 3e-52 178.0 9.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXX78856.1 - 6.8e-34 117.3 0.0 1.7e-33 116.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXX78856.1 - 5.1e-06 26.1 0.0 0.00024 20.6 0.0 2.3 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXX78856.1 - 0.0051 17.1 0.1 0.032 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXX78856.1 - 0.0058 17.0 0.1 0.076 13.4 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX78856.1 - 0.014 15.8 0.1 0.038 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXX78856.1 - 0.014 15.1 0.1 0.043 13.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXX78856.1 - 0.025 14.6 0.1 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PrgI PF12666.7 KXX78856.1 - 0.033 14.9 2.5 6 7.7 0.5 2.8 2 0 0 2 2 2 0 PrgI family protein SbcCD_C PF13558.6 KXX78856.1 - 0.13 12.5 1.6 1.8 8.9 1.6 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sigma54_activ_2 PF14532.6 KXX78856.1 - 0.15 12.2 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXX78856.1 - 0.18 11.5 0.1 0.49 10.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.9 KXX78856.1 - 0.32 9.7 1.2 0.38 9.5 0.2 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DIM PF08194.12 KXX78856.1 - 1.9 8.7 3.9 79 3.6 0.0 3.6 3 0 0 3 3 3 0 DIM protein Spt4 PF06093.13 KXX78857.1 - 4.7e-32 109.9 0.1 5.8e-32 109.6 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Kin17_mid PF10357.9 KXX78858.1 - 4.3e-45 152.7 3.5 9.3e-45 151.6 3.5 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KXX78858.1 - 0.00013 22.2 3.3 0.00025 21.2 3.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX78858.1 - 0.0011 19.3 3.5 0.002 18.5 3.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXX78858.1 - 0.011 16.0 1.8 0.011 16.0 1.8 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) 7tm_1 PF00001.21 KXX78859.1 - 7.2e-13 48.5 0.9 8.9e-13 48.2 0.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 KXX78859.1 - 8.5e-13 48.2 4.0 8.5e-13 48.2 4.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KXX78859.1 - 2.4e-12 46.6 8.4 2.4e-12 46.6 8.4 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KXX78859.1 - 2.1e-07 30.9 10.1 2.1e-07 30.9 10.1 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KXX78859.1 - 8.2e-06 25.4 2.6 1.4e-05 24.6 2.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx STE3 PF02076.15 KXX78859.1 - 0.00019 20.8 6.3 0.00019 20.8 6.3 2.0 2 0 0 2 2 2 1 Pheromone A receptor Vps39_2 PF10367.9 KXX78860.1 - 3.4e-05 24.2 0.0 7.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KXX78860.1 - 0.0018 18.1 0.0 0.058 13.3 0.0 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KXX78860.1 - 0.074 13.3 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.12 KXX78861.1 - 3.6e-100 334.5 6.5 5.4e-96 320.8 0.0 2.6 2 0 0 2 2 2 2 CASP C terminal ADIP PF11559.8 KXX78861.1 - 0.0087 16.2 5.2 0.0087 16.2 5.2 6.6 5 1 2 7 7 7 3 Afadin- and alpha -actinin-Binding SKA1 PF07160.12 KXX78861.1 - 0.018 14.9 19.4 0.57 10.0 8.4 3.8 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 1 Cep57_MT_bd PF06657.13 KXX78861.1 - 0.027 14.9 3.0 0.027 14.9 3.0 5.8 6 0 0 6 6 6 0 Centrosome microtubule-binding domain of Cep57 SOGA PF11365.8 KXX78861.1 - 0.034 15.3 1.0 0.034 15.3 1.0 5.8 2 1 2 5 5 5 0 Protein SOGA Trimer_CC PF08954.11 KXX78861.1 - 0.17 11.5 7.1 1.1 8.8 0.6 3.2 2 0 0 2 2 2 0 Trimerisation motif APG6_N PF17675.1 KXX78861.1 - 0.23 12.0 60.3 1.6 9.2 11.4 5.7 2 1 3 5 5 5 0 Apg6 coiled-coil region LMBR1 PF04791.16 KXX78861.1 - 0.25 10.2 8.4 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 LMBR1-like membrane protein Virulence_fact PF13769.6 KXX78861.1 - 0.32 11.2 3.5 1.2 9.4 1.6 2.9 3 0 0 3 3 3 0 Virulence factor TPR_MLP1_2 PF07926.12 KXX78861.1 - 2.6 8.1 63.4 0.41 10.7 9.8 6.9 5 2 1 6 6 6 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KXX78861.1 - 4.4 7.7 46.1 1.1 9.6 4.8 4.6 3 1 2 5 5 5 0 Fez1 DUF1664 PF07889.12 KXX78861.1 - 6.2 6.9 28.7 2.3 8.2 0.1 6.1 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) PI3K_P85_iSH2 PF16454.5 KXX78861.1 - 7.4 6.1 37.3 1.1 8.9 2.2 5.1 3 2 2 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HAP1_N PF04849.13 KXX78861.1 - 8.7 5.4 42.7 0.91 8.7 0.1 5.0 3 1 2 5 5 5 0 HAP1 N-terminal conserved region UPF0184 PF03670.13 KXX78861.1 - 9.3 6.7 10.5 0.87 10.0 0.1 3.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) AAA_16 PF13191.6 KXX78862.1 - 4.9e-07 30.3 0.0 2.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KXX78862.1 - 5.7e-06 26.3 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 KXX78862.1 - 0.00013 22.2 0.1 0.00031 20.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KXX78862.1 - 0.0042 17.4 0.0 0.015 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXX78862.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KXX78862.1 - 0.013 16.0 0.0 0.062 13.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX78862.1 - 0.014 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KXX78862.1 - 0.021 14.6 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXX78862.1 - 0.039 14.4 1.1 0.21 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXX78862.1 - 0.045 14.3 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KXX78862.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T3SSipB PF16535.5 KXX78862.1 - 0.095 13.2 0.1 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 Type III cell invasion protein SipB T2SSE PF00437.20 KXX78862.1 - 0.14 11.2 0.0 0.61 9.1 0.0 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KXX78862.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_51 PF18558.1 KXX78862.1 - 0.14 12.0 0.1 3.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain MMR_HSR1 PF01926.23 KXX78862.1 - 0.19 11.8 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-C2H2 PF00096.26 KXX78863.1 - 4.8e-05 23.6 18.0 0.32 11.5 0.8 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX78863.1 - 0.078 13.9 19.4 1.4 9.9 0.6 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger zf-TAZ PF02135.16 KXX78863.1 - 0.28 11.7 3.6 0.43 11.1 1.2 2.1 2 0 0 2 2 2 0 TAZ zinc finger TT_ORF2 PF02957.15 KXX78863.1 - 2.3 9.2 6.6 0.3 12.0 2.0 1.9 2 0 0 2 2 2 0 TT viral ORF2 FOXP-CC PF16159.5 KXX78863.1 - 6.6 7.5 6.8 24 5.6 1.2 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain Fibrillarin PF01269.17 KXX78864.1 - 1.1e-103 345.2 0.0 1.4e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KXX78864.1 - 3.9e-06 26.7 0.0 5.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KXX78864.1 - 0.0047 16.7 0.1 0.007 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KXX78864.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ribosomal_L22 PF00237.19 KXX78865.1 - 5.1e-41 139.1 0.0 7.4e-41 138.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 KXX78865.1 - 0.01 16.2 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 0 Lamin Tail Domain Peptidase_C12 PF01088.21 KXX78866.1 - 3.8e-70 235.9 0.0 4.8e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXX78866.1 - 2.7e-10 40.0 0.1 5.8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases zf-rbx1 PF12678.7 KXX78867.1 - 4e-10 39.8 4.9 7.1e-10 39.0 4.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXX78867.1 - 1.8e-09 37.8 5.3 3.4e-09 36.9 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX78867.1 - 8.1e-06 25.6 3.5 1.4e-05 24.9 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX78867.1 - 6.3e-05 22.9 1.8 0.00013 21.9 1.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXX78867.1 - 7.2e-05 22.6 6.8 0.0012 18.6 7.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX78867.1 - 8.2e-05 22.5 2.5 0.00026 20.9 2.7 1.7 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXX78867.1 - 0.0003 20.6 1.6 0.00068 19.4 1.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXX78867.1 - 0.0004 20.4 0.5 0.00082 19.4 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXX78867.1 - 0.00053 19.6 0.6 0.00053 19.6 0.6 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KXX78867.1 - 0.0023 17.7 6.6 0.0052 16.6 6.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXX78867.1 - 0.051 13.3 1.7 0.45 10.3 1.7 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-FPG_IleRS PF06827.14 KXX78867.1 - 0.12 12.3 0.9 0.27 11.1 0.9 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-RING_4 PF14570.6 KXX78867.1 - 0.79 9.6 3.2 1.9 8.3 3.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXX78867.1 - 2.4 8.4 4.8 2.3 8.5 2.7 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain Methyltransf_16 PF10294.9 KXX78868.1 - 5.5e-05 23.0 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF3455 PF11937.8 KXX78870.1 - 3.4e-42 144.5 0.2 4.6e-42 144.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KXX78870.1 - 0.0021 18.1 2.5 0.0039 17.3 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2990) Pkinase PF00069.25 KXX78871.1 - 4.1e-09 36.2 0.0 5.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PWI PF01480.17 KXX78871.1 - 0.11 12.8 0.0 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 PWI domain Ribosomal_S9 PF00380.19 KXX78873.1 - 1.7e-40 138.3 1.0 2.7e-40 137.7 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF3168 PF11367.8 KXX78873.1 - 0.12 12.6 0.6 4.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) EF1G PF00647.19 KXX78874.1 - 5.2e-45 151.9 0.1 8.9e-45 151.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KXX78874.1 - 5.2e-16 58.6 0.0 1.2e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXX78874.1 - 4.6e-13 49.3 0.1 1.7e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX78874.1 - 1.1e-09 38.2 0.1 3e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX78874.1 - 2.7e-07 30.9 0.0 6.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXX78874.1 - 5.9e-06 26.4 0.1 1.7e-05 24.9 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXX78874.1 - 0.008 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PTS_IIA PF02255.16 KXX78874.1 - 0.21 11.6 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit NIF PF03031.18 KXX78875.1 - 1.5e-16 60.5 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AMPK1_CBM PF16561.5 KXX78876.1 - 2.2e-26 91.9 0.0 3.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KXX78876.1 - 1.5e-19 70.0 1.5 1.5e-19 70.0 1.5 2.5 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Peptidase_M22 PF00814.25 KXX78877.1 - 1.4e-84 284.1 0.0 1.6e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family EPL1 PF10513.9 KXX78878.1 - 4.9e-22 79.0 2.4 4.9e-22 79.0 2.4 2.2 2 1 0 2 2 2 1 Enhancer of polycomb-like RNA_pol_Rpb1_1 PF04997.12 KXX78878.1 - 0.0075 15.6 2.5 0.012 14.9 2.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RelB_N PF18506.1 KXX78878.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain Erythro_esteras PF05139.14 KXX78878.1 - 0.23 11.2 2.6 0.47 10.2 2.6 1.6 1 1 0 1 1 1 0 Erythromycin esterase EF-hand_1 PF00036.32 KXX78879.1 - 6.2e-27 91.1 13.1 1.7e-07 30.2 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXX78879.1 - 5.4e-23 81.2 14.2 5e-14 52.5 1.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXX78879.1 - 4.3e-20 69.9 7.9 4.9e-05 22.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXX78879.1 - 6.2e-18 63.4 10.7 1.9e-06 27.1 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXX78879.1 - 3.1e-13 49.4 12.7 5.8e-05 22.9 0.8 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXX78879.1 - 7.6e-07 29.4 0.1 0.002 18.4 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXX78879.1 - 1.7e-05 24.7 8.8 0.011 15.6 0.5 3.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXX78879.1 - 0.031 14.6 0.2 1.1 9.7 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 KXX78879.1 - 0.057 13.6 2.7 0.32 11.2 2.6 2.3 1 1 1 2 2 2 0 Dockerin type I domain Anillin PF08174.11 KXX78879.1 - 0.082 13.3 0.0 2.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Cell division protein anillin Clathrin_lg_ch PF01086.17 KXX78880.1 - 2.5e-77 260.0 3.9 2.8e-77 259.9 3.9 1.0 1 0 0 1 1 1 1 Clathrin light chain Mito_carr PF00153.27 KXX78881.1 - 9.6e-30 102.4 0.3 3.4e-14 52.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HET PF06985.11 KXX78882.1 - 7.5e-13 49.1 6.8 9.4e-11 42.3 0.9 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Cupin_8 PF13621.6 KXX78883.1 - 1.4e-29 103.6 0.0 2.3e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXX78883.1 - 2e-07 30.8 0.0 1.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KXX78883.1 - 0.00033 21.1 0.0 0.0064 16.9 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KXX78883.1 - 0.099 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain WD40 PF00400.32 KXX78884.1 - 1.3e-05 25.8 8.5 0.001 19.8 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX78884.1 - 0.0024 18.1 0.2 2.2 8.6 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2457 PF10446.9 KXX78884.1 - 0.07 12.3 14.3 0.11 11.6 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ge1_WD40 PF16529.5 KXX78884.1 - 0.1 11.6 0.2 6.9 5.5 0.1 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GCIP PF13324.6 KXX78884.1 - 0.15 11.6 0.6 0.23 11.1 0.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 KXX78884.1 - 0.22 9.8 1.9 0.29 9.4 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KXX78884.1 - 0.38 10.6 3.4 0.58 10.0 3.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KXX78884.1 - 0.47 8.5 11.2 0.62 8.1 11.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KXX78884.1 - 0.6 9.5 4.0 0.84 9.0 4.0 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KXX78884.1 - 0.61 9.3 15.3 0.95 8.7 15.3 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KXX78884.1 - 2.3 6.3 5.2 3.2 5.9 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KXX78884.1 - 3.3 6.2 4.6 4.5 5.7 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.11 KXX78884.1 - 9.1 6.3 5.7 16 5.5 5.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Glycos_transf_4 PF00953.21 KXX78885.1 - 1.5e-33 116.0 9.7 1.5e-33 116.0 9.7 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 EF-hand_7 PF13499.6 KXX78886.1 - 1.1e-24 86.6 6.6 3.9e-16 59.3 1.1 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KXX78886.1 - 6.1e-24 81.7 11.8 3.2e-08 32.5 0.2 4.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KXX78886.1 - 8e-24 81.5 5.2 6.6e-07 28.8 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KXX78886.1 - 1.7e-16 58.9 12.4 3.8e-05 23.0 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KXX78886.1 - 3.3e-15 55.7 11.2 9.7e-06 25.3 0.7 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KXX78886.1 - 6.9e-08 32.4 7.1 0.0051 16.7 0.1 3.7 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXX78886.1 - 6.1e-05 23.3 0.8 0.0012 19.1 0.1 2.6 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXX78886.1 - 0.00097 19.4 1.4 0.84 10.0 0.3 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KXX78886.1 - 0.049 13.5 2.8 0.62 10.0 0.0 3.3 4 1 0 4 4 4 0 EF hand EF-hand_14 PF17959.1 KXX78886.1 - 0.14 12.5 1.1 7.8 6.9 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain AMP-binding PF00501.28 KXX78887.1 - 1.5e-88 297.2 0.0 2.3e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX78887.1 - 0.0043 18.0 0.2 0.014 16.3 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdhD PF03599.16 KXX78887.1 - 0.0047 15.7 0.0 0.0077 15.0 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Methyltransf_23 PF13489.6 KXX78888.1 - 9.4e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX78888.1 - 1e-09 38.9 0.0 2.6e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX78888.1 - 1.7e-08 34.4 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXX78888.1 - 1.4e-07 32.0 0.0 2.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX78888.1 - 1.3e-06 29.0 0.2 9.7e-06 26.3 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXX78888.1 - 0.00017 21.8 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KXX78888.1 - 0.042 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXX78888.1 - 0.052 12.9 0.0 0.23 10.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXX78888.1 - 0.064 12.7 0.0 0.17 11.3 0.0 1.8 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 KXX78888.1 - 0.073 12.3 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain HEPN_RES_NTD1 PF18870.1 KXX78888.1 - 0.099 12.8 0.0 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 HEPN/RES N-terminal domain 1 CDC45 PF02724.14 KXX78889.1 - 3e-231 769.2 0.0 7e-230 764.7 0.0 1.9 1 1 1 2 2 2 1 CDC45-like protein Methyltransf_16 PF10294.9 KXX78890.1 - 3.8e-14 52.8 0.0 5.1e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Transglut_core PF01841.19 KXX78891.1 - 6.2e-10 39.5 0.0 2.5e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 KXX78891.1 - 0.089 13.8 0.0 0.25 12.4 0.0 1.9 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase GST_N_2 PF13409.6 KXX78894.1 - 4.2e-23 81.4 0.0 2.2e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX78894.1 - 5.4e-16 58.4 0.1 1.2e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX78894.1 - 1.3e-06 28.5 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX78894.1 - 3e-06 27.6 0.1 7.1e-05 23.1 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXX78894.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXX78894.1 - 0.036 14.6 0.0 0.063 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PhetRS_B1 PF18262.1 KXX78894.1 - 0.16 12.2 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain UQ_con PF00179.26 KXX78895.1 - 3.8e-24 84.9 0.0 7.2e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.7 KXX78895.1 - 4.8e-17 62.3 0.0 7.4e-07 29.7 0.0 3.8 2 1 2 4 4 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX78895.1 - 3.7e-16 58.8 0.4 0.023 15.2 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXX78895.1 - 8.8e-11 41.8 2.7 6.2e-05 23.2 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.12 KXX78895.1 - 1.2e-10 41.6 0.0 2.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 KXX78895.1 - 2.3e-10 40.8 0.3 0.00033 21.1 0.1 3.4 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX78895.1 - 1.5e-09 37.2 0.5 0.13 12.8 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat AAA_16 PF13191.6 KXX78895.1 - 0.00029 21.3 0.1 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX78895.1 - 0.0018 18.5 0.2 0.0063 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain SesA PF17107.5 KXX78895.1 - 0.011 15.9 0.0 0.068 13.4 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXX78895.1 - 0.029 13.7 0.7 0.2 11.0 0.0 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins KAP_NTPase PF07693.14 KXX78895.1 - 0.17 11.1 0.1 5.7 6.1 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Cyclin_N PF00134.23 KXX78895.1 - 0.23 11.2 0.7 24 4.7 0.1 3.2 3 0 0 3 3 3 0 Cyclin, N-terminal domain FKBP_C PF00254.28 KXX78896.1 - 4.9e-27 94.1 0.0 5.8e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.21 KXX78897.1 - 3.4e-111 370.4 0.0 2.4e-75 253.0 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KXX78897.1 - 5.5e-86 288.6 1.2 5.5e-86 288.6 1.2 2.2 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KXX78897.1 - 1.5e-32 111.6 0.1 4e-32 110.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KXX78897.1 - 3.8e-25 87.9 1.0 7.7e-25 86.9 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 KXX78897.1 - 1.2e-19 70.8 1.7 1e-18 67.8 0.6 2.4 2 0 0 2 2 2 1 Ubiquitin fold domain NAD_binding_7 PF13241.6 KXX78897.1 - 0.039 14.4 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Tap-RNA_bind PF09162.10 KXX78897.1 - 0.1 12.5 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Tap, RNA-binding MFS_1 PF07690.16 KXX78898.1 - 3.2e-24 85.5 27.4 3.2e-24 85.5 27.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily 2TM PF13239.6 KXX78898.1 - 0.023 15.0 0.9 1.9 8.9 0.7 3.5 2 2 0 2 2 2 0 2TM domain CDC45 PF02724.14 KXX78898.1 - 2.1 6.5 8.0 3.2 5.9 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 KXX78898.1 - 3.3 8.7 10.0 6.8 7.7 10.0 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CD99L2 PF12301.8 KXX78899.1 - 0.025 14.9 0.3 0.025 14.9 0.3 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 LRR_4 PF12799.7 KXX78900.1 - 0.0052 17.2 2.8 20 5.8 0.0 5.2 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXX78900.1 - 0.069 13.2 1.2 27 5.2 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat zf-C2H2 PF00096.26 KXX78901.1 - 5.4e-05 23.4 8.7 0.02 15.3 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX78901.1 - 0.0046 17.7 7.8 0.083 13.8 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Docking PF08990.11 KXX78901.1 - 0.1 12.2 2.1 0.23 11.1 2.1 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking zf-C2H2_jaz PF12171.8 KXX78901.1 - 0.26 11.6 3.3 1.2 9.5 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Hexapep PF00132.24 KXX78902.1 - 1.1e-06 28.1 3.0 0.0002 20.9 0.7 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KXX78902.1 - 2.6e-06 26.6 2.0 0.00014 20.9 2.0 2.1 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KXX78902.1 - 1.5e-05 25.4 0.0 2.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KXX78902.1 - 0.00043 19.9 0.0 0.00092 18.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KXX78902.1 - 0.012 13.7 1.2 0.024 12.8 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) TFIIA PF03153.13 KXX78902.1 - 0.017 15.1 6.6 0.023 14.7 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hexapep_2 PF14602.6 KXX78902.1 - 0.13 12.1 6.5 0.39 10.5 2.3 2.9 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Cwf_Cwc_15 PF04889.12 KXX78902.1 - 5.7 6.6 19.0 9 5.9 19.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Bul1_C PF04426.12 KXX78903.1 - 4.7e-07 29.5 3.0 6.5e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 Bul1 C terminus Arrestin_C PF02752.22 KXX78903.1 - 7.1e-06 26.5 2.3 0.035 14.6 1.1 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Bul1_N PF04425.12 KXX78903.1 - 0.00043 19.2 10.8 0.0034 16.2 0.1 3.1 3 1 1 4 4 4 2 Bul1 N terminus Arrestin_N PF00339.29 KXX78903.1 - 0.0016 18.5 0.0 0.012 15.7 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 KXX78903.1 - 0.016 14.3 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 SPX PF03105.19 KXX78903.1 - 6.2 6.6 9.8 0.47 10.3 4.8 1.6 2 0 0 2 2 2 0 SPX domain Zip PF02535.22 KXX78904.1 - 4.6e-60 203.6 6.8 8.2e-60 202.8 6.8 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Aconitase PF00330.20 KXX78905.1 - 2.3e-164 547.8 0.1 2.9e-164 547.5 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXX78905.1 - 3.7e-41 140.5 0.0 6.4e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Zn_clus PF00172.18 KXX78906.1 - 0.00074 19.6 3.4 0.002 18.2 3.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX78906.1 - 0.0026 16.6 0.0 0.0049 15.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.33 KXX78907.1 - 9.2e-07 28.6 0.0 2.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX78907.1 - 1.8e-06 27.7 0.0 4.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like FadA PF09403.10 KXX78907.1 - 0.9 10.1 4.5 18 5.9 0.2 2.9 1 1 1 2 2 2 0 Adhesion protein FadA Cu_amine_oxid PF01179.20 KXX78908.1 - 7.6e-162 538.9 0.0 9.1e-162 538.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXX78908.1 - 2.3e-06 27.8 0.1 8.7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXX78908.1 - 0.044 14.2 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain SET PF00856.28 KXX78909.1 - 1.8e-11 44.8 0.0 3.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 SET domain LPD11 PF18824.1 KXX78909.1 - 0.0019 18.3 0.1 0.0043 17.1 0.1 1.6 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 11 Peptidase_S66 PF02016.15 KXX78909.1 - 0.0019 18.3 0.1 1.2 9.3 0.0 2.4 1 1 1 2 2 2 2 LD-carboxypeptidase N-terminal domain CENP-S PF15630.6 KXX78911.1 - 3.4e-33 113.8 0.2 8.2e-33 112.6 0.1 1.6 1 1 1 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 KXX78911.1 - 4.2e-08 33.3 0.2 4.8e-08 33.1 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXX78911.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DUF2972 PF11186.8 KXX78911.1 - 0.052 13.5 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) TFIID-18kDa PF02269.16 KXX78911.1 - 0.062 13.3 0.1 0.078 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit UCH PF00443.29 KXX78912.1 - 2.8e-21 76.2 0.0 4.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXX78912.1 - 7.4e-12 45.4 0.1 1.6e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXX78912.1 - 0.0073 15.9 0.4 0.079 12.5 0.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Utp13 PF08625.11 KXX78913.1 - 2e-51 173.7 0.3 3.1e-51 173.0 0.3 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KXX78913.1 - 2.9e-44 148.2 18.7 3.8e-07 30.7 0.0 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX78913.1 - 4.1e-14 52.6 2.9 0.12 12.7 0.0 8.8 6 2 3 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KXX78913.1 - 7.7e-05 21.6 5.5 7 5.3 0.0 6.1 4 3 2 7 7 7 3 Nup133 N terminal like Nup160 PF11715.8 KXX78913.1 - 0.00034 19.4 2.7 0.22 10.1 0.1 4.7 4 2 1 5 5 5 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXX78913.1 - 0.0019 17.2 0.0 0.52 9.2 0.0 3.6 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KXX78914.1 - 3e-08 34.3 0.1 8.6e-08 32.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KXX78914.1 - 0.041 13.4 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KXX78914.1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 KXX78914.1 - 0.18 11.6 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NACHT PF05729.12 KXX78916.1 - 1.2e-10 41.6 0.2 4e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX78916.1 - 9.7e-07 29.3 1.7 2.9e-06 27.8 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 KXX78916.1 - 3.6e-05 23.2 0.1 6.9e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_18 PF13238.6 KXX78916.1 - 0.013 16.0 0.0 0.058 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXX78916.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain HTH_30 PF13556.6 KXX78916.1 - 0.027 14.3 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Rx_N PF18052.1 KXX78916.1 - 0.03 14.6 0.1 0.087 13.1 0.1 1.8 1 0 0 1 1 1 0 Rx N-terminal domain APS_kinase PF01583.20 KXX78916.1 - 0.091 12.7 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KXX78916.1 - 0.098 12.4 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KXX78916.1 - 0.1 12.7 0.6 0.49 10.5 0.1 2.4 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain NPV_P10 PF05531.12 KXX78916.1 - 0.15 12.5 0.1 13 6.3 0.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 KXX78916.1 - 0.17 12.5 0.1 0.44 11.1 0.1 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Gp58 PF07902.11 KXX78916.1 - 0.21 9.8 0.4 0.32 9.2 0.4 1.1 1 0 0 1 1 1 0 gp58-like protein KAP_NTPase PF07693.14 KXX78916.1 - 0.24 10.6 0.5 0.54 9.4 0.2 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Fungal_trans_2 PF11951.8 KXX78917.1 - 1.6e-32 112.8 0.5 1.5e-19 70.1 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX78917.1 - 2.4e-08 34.0 11.5 4e-08 33.2 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.28 KXX78918.1 - 2e-05 24.2 0.2 0.21 11.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX78918.1 - 6.1e-05 22.8 1.8 0.98 9.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX78918.1 - 0.0025 18.0 3.2 0.013 15.8 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat UBA PF00627.31 KXX78918.1 - 0.017 15.0 0.0 0.049 13.6 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain DnaJ PF00226.31 KXX78918.1 - 0.063 13.4 0.2 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 DnaJ domain TPR_19 PF14559.6 KXX78918.1 - 0.08 13.5 0.2 0.08 13.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat APS_kinase PF01583.20 KXX78918.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1996 PF09362.10 KXX78919.1 - 2.9e-83 279.4 0.1 3.9e-83 279.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CENP-B_dimeris PF09026.10 KXX78920.1 - 0.031 14.7 0.6 0.062 13.7 0.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Gemini_mov PF01708.16 KXX78920.1 - 0.2 11.5 0.3 0.56 10.0 0.3 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein LSM PF01423.22 KXX78922.1 - 7.7e-17 60.7 0.2 1.1e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain Ribosomal_S21e PF01249.18 KXX78922.1 - 0.04 14.0 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S21e Ammonium_transp PF00909.21 KXX78923.1 - 0.026 13.2 0.8 0.043 12.5 0.8 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family UQ_con PF00179.26 KXX78924.1 - 1.7e-51 173.6 0.0 1.9e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX78924.1 - 0.16 11.6 0.1 0.33 10.7 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B MTHFR PF02219.17 KXX78925.1 - 8.4e-101 337.1 0.0 1.3e-100 336.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase IF4E PF01652.18 KXX78926.1 - 2.4e-55 186.7 0.0 3.9e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Coilin_N PF15862.5 KXX78926.1 - 0.018 14.9 7.7 0.028 14.2 7.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF4834 PF16118.5 KXX78926.1 - 4.1 8.4 9.6 8.7 7.4 9.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF572 PF04502.13 KXX78927.1 - 1.2e-60 205.9 0.8 1.2e-60 205.9 0.8 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF572) Gin PF10764.9 KXX78927.1 - 0.11 12.5 0.5 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Glyco_hydro_18 PF00704.28 KXX78928.1 - 9.1e-16 58.5 0.0 1.5e-15 57.7 0.0 1.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_transf_15 PF01793.16 KXX78929.1 - 8.8e-118 393.3 5.9 1e-117 393.0 5.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 KXX78930.1 - 1.7e-38 133.0 0.0 2.7e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXX78930.1 - 3.8e-29 102.1 0.0 7.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KXX78930.1 - 9.7e-05 20.9 0.0 0.00042 18.8 0.0 1.8 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Zn_clus PF00172.18 KXX78931.1 - 2.5e-06 27.5 8.6 4.4e-06 26.7 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KXX78932.1 - 3.1e-19 68.9 7.0 0.00021 22.0 0.2 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX78932.1 - 2.6e-07 30.8 0.1 0.49 10.7 0.0 5.0 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX78932.1 - 0.0092 14.7 1.1 3.9 6.0 0.0 3.4 2 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ PF01011.21 KXX78932.1 - 0.11 12.5 4.1 4.4 7.4 0.0 4.4 5 0 0 5 5 5 0 PQQ enzyme repeat PQ-loop PF04193.14 KXX78934.1 - 2.2e-19 69.0 6.1 6.9e-13 48.2 2.8 2.9 2 0 0 2 2 2 2 PQ loop repeat HET PF06985.11 KXX78936.1 - 3.1e-27 95.7 0.2 5.6e-27 94.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_ligase_A_M PF01068.21 KXX78937.1 - 2.6e-46 157.9 0.0 4.2e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXX78937.1 - 2.4e-38 132.2 0.0 5.3e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KXX78937.1 - 2.5e-16 60.4 0.0 7.1e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_C PF04679.15 KXX78937.1 - 3.6e-16 59.6 0.3 4.7e-15 56.0 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KXX78937.1 - 4.3e-14 52.7 0.0 6.8e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXX78937.1 - 1.4e-06 28.6 0.0 3.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KXX78937.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV mRNA_cap_enzyme PF01331.19 KXX78937.1 - 0.028 14.2 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain LIG3_BRCT PF16759.5 KXX78937.1 - 0.12 12.7 0.0 6.6 7.1 0.0 2.7 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain ATG16 PF08614.11 KXX78938.1 - 1.4e-54 185.4 12.2 1.6e-54 185.2 12.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 KXX78938.1 - 0.01 15.0 11.5 0.095 11.8 9.6 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF4201 PF13870.6 KXX78938.1 - 0.012 15.4 9.6 0.012 15.4 9.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF2461 PF09365.10 KXX78938.1 - 0.14 12.1 2.6 0.21 11.5 2.6 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) UPF0242 PF06785.11 KXX78938.1 - 0.15 12.1 10.5 6.4 6.8 5.7 2.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KXX78938.1 - 0.15 11.4 13.8 0.31 10.4 10.6 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KXX78938.1 - 0.38 9.3 5.4 0.53 8.9 5.4 1.2 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 KXX78938.1 - 0.39 11.2 15.0 2.2 8.8 0.5 3.4 3 0 0 3 3 3 0 Cell division protein ZapB DUF4407 PF14362.6 KXX78938.1 - 0.44 9.9 10.7 15 4.8 10.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 KXX78938.1 - 0.66 10.3 7.5 16 5.9 2.2 3.2 3 1 0 3 3 3 0 TSC-22/dip/bun family MSA-2c PF12238.8 KXX78938.1 - 1.3 9.0 4.2 2.2 8.2 4.2 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Atg14 PF10186.9 KXX78938.1 - 3.2 6.8 13.3 0.37 9.8 9.4 1.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 KXX78938.1 - 5.1 7.8 8.4 59 4.4 4.3 3.0 2 1 1 3 3 3 0 Initiation control protein YabA DUF4140 PF13600.6 KXX78938.1 - 6.9 7.2 18.4 1.3 9.5 0.5 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DOT1 PF08123.13 KXX78939.1 - 3.7e-72 242.2 0.0 5.8e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KXX78939.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1129 PF06570.11 KXX78939.1 - 0.012 15.2 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Methyltransf_25 PF13649.6 KXX78939.1 - 0.047 14.4 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF4813 PF16072.5 KXX78939.1 - 0.075 12.7 17.6 0.59 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Methyltransf_11 PF08241.12 KXX78939.1 - 0.092 13.4 0.1 0.99 10.1 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain Mucin PF01456.17 KXX78940.1 - 0.00016 21.7 7.3 0.00023 21.2 7.3 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein MGC-24 PF05283.11 KXX78940.1 - 0.00038 20.9 3.4 0.00074 20.0 3.4 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Peptidase_M16_C PF05193.21 KXX78941.1 - 3e-63 213.1 0.0 1.3e-62 211.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXX78941.1 - 3.9e-43 147.0 0.0 7.1e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Disulph_isomer PF06491.11 KXX78941.1 - 0.069 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Disulphide isomerase AAA_5 PF07728.14 KXX78941.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) S1 PF00575.23 KXX78943.1 - 4.6e-85 280.0 28.3 1.1e-16 60.9 0.2 13.4 13 0 0 13 13 13 11 S1 RNA binding domain TPR_14 PF13428.6 KXX78943.1 - 8.4e-06 26.2 7.7 0.39 11.6 0.0 5.7 6 1 1 7 7 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX78943.1 - 1e-05 25.9 0.3 0.0089 16.5 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 KXX78943.1 - 5.2e-05 23.4 8.3 0.00088 19.3 0.2 3.8 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) RNase_II_C_S1 PF18614.1 KXX78943.1 - 0.0012 18.8 5.1 1.7 8.6 0.1 5.5 6 0 0 6 6 6 1 RNase II-type exonuclease C-terminal S1 domain TPR_6 PF13174.6 KXX78943.1 - 0.0015 19.0 0.7 12 6.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat S1_2 PF13509.6 KXX78943.1 - 0.0018 18.3 0.2 22 5.2 0.0 5.4 4 0 0 4 4 4 0 S1 domain TPR_17 PF13431.6 KXX78943.1 - 0.0023 18.2 0.1 0.5 10.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXX78943.1 - 0.0061 16.6 0.1 0.15 12.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PCB_OB PF17092.5 KXX78943.1 - 0.012 16.3 16.8 16 6.3 0.2 9.1 10 2 1 11 11 10 0 Penicillin-binding protein OB-like domain TPR_12 PF13424.6 KXX78943.1 - 0.028 14.7 0.1 0.21 11.9 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX78943.1 - 0.046 13.9 0.0 0.86 10.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ID PF18543.1 KXX78943.1 - 0.53 10.3 2.0 2.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Intracellular delivery domain MAP65_ASE1 PF03999.12 KXX78946.1 - 1.6e-73 248.4 22.8 5e-73 246.8 22.8 1.8 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.11 KXX78946.1 - 3.1 5.6 6.6 1.6 6.6 0.1 2.3 2 1 1 3 3 3 0 Prominin Fib_alpha PF08702.10 KXX78946.1 - 6.6 6.9 7.4 8.5 6.6 0.1 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 KXX78946.1 - 7.8 7.0 18.0 0.19 12.2 1.6 3.8 3 1 0 3 3 3 0 Spectrin repeat DUF1720 PF08226.11 KXX78947.1 - 5.9 7.4 12.9 0.12 12.8 1.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1720) p450 PF00067.22 KXX78948.1 - 3.6e-32 111.7 0.0 7e-32 110.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Caa3_CtaG PF09678.10 KXX78948.1 - 0.13 11.7 0.4 13 5.2 0.0 2.3 1 1 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Vps16_N PF04841.13 KXX78949.1 - 5e-96 322.0 0.0 6.9e-96 321.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KXX78949.1 - 3.4e-79 266.2 0.0 5.1e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KXX78949.1 - 0.0099 16.2 0.0 0.23 11.8 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 KXX78950.1 - 7.5e-16 58.2 0.0 1.8e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KXX78950.1 - 3.7e-13 49.0 9.4 7.8e-13 47.9 9.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXX78950.1 - 3.3e-06 27.3 12.5 5.4e-06 26.6 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KXX78950.1 - 0.015 15.6 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-HC5HC2H PF13771.6 KXX78950.1 - 0.024 14.9 1.9 0.044 14.0 1.9 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 KXX78950.1 - 0.044 13.7 9.3 0.073 13.0 9.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KXX78950.1 - 0.045 13.6 12.5 0.08 12.8 12.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX78950.1 - 0.048 14.0 7.3 0.11 12.9 7.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXX78950.1 - 0.071 13.2 2.5 0.12 12.4 2.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KXX78950.1 - 0.12 12.2 11.3 0.22 11.4 11.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX78950.1 - 0.6 10.2 11.2 1.3 9.1 11.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF3439 PF11921.8 KXX78950.1 - 3.7 7.5 10.5 2.5 8.1 7.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) UPRTase PF14681.6 KXX78952.1 - 3.1e-74 248.9 0.0 3.5e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXX78952.1 - 0.0074 15.8 0.0 0.015 14.9 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 KXX78952.1 - 0.065 13.3 0.0 0.095 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain TMP-TENI PF02581.17 KXX78952.1 - 0.12 11.7 0.8 0.5 9.7 0.3 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase CRCB PF02537.15 KXX78953.1 - 1.6e-38 130.9 10.4 2.6e-23 82.2 8.8 2.4 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF4449 PF14613.6 KXX78954.1 - 2.6e-67 226.0 0.5 2.6e-67 226.0 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) TPPII_N PF12583.8 KXX78954.1 - 0.032 14.8 0.8 0.032 14.8 0.8 2.4 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Prp18 PF02840.15 KXX78954.1 - 0.045 13.8 4.4 1.5 8.8 0.0 3.1 2 1 1 3 3 3 0 Prp18 domain ExsD PF16806.5 KXX78954.1 - 0.3 11.0 2.3 2 8.3 0.3 2.3 2 0 0 2 2 2 0 Antiactivator protein ExsD tRNA-synt_1g PF09334.11 KXX78955.1 - 2.9e-144 480.7 0.2 1.2e-143 478.6 0.2 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXX78955.1 - 5.1e-08 31.6 0.1 0.0055 15.0 0.0 4.0 3 1 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) B5 PF03484.15 KXX78955.1 - 0.15 12.4 0.0 0.65 10.3 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetase B5 domain Mac PF12464.8 KXX78955.1 - 0.54 10.5 2.1 2.5 8.4 0.0 2.8 2 0 0 2 2 2 0 Maltose acetyltransferase K_channel_TID PF07941.11 KXX78955.1 - 0.8 10.2 4.1 1.5 9.3 4.1 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Lactamase_B PF00753.27 KXX78956.1 - 1.2e-08 35.2 0.3 5.8e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXX78956.1 - 0.00049 19.7 1.0 0.43 10.1 0.0 2.6 2 1 0 2 2 2 2 Beta-lactamase superfamily domain HET PF06985.11 KXX78958.1 - 1.4e-24 87.1 0.1 1.5e-23 83.7 0.1 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABA_GPCR PF12430.8 KXX78960.1 - 7.7e-59 198.5 0.0 7.7e-59 198.5 0.0 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KXX78960.1 - 4.2e-26 90.8 0.2 8.1e-25 86.7 0.0 2.8 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Ank_2 PF12796.7 KXX78961.1 - 6.1e-16 58.8 0.1 4.5e-07 30.4 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX78961.1 - 5.1e-13 49.3 0.5 0.00019 21.9 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX78961.1 - 7.7e-10 38.2 3.7 0.02 15.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXX78961.1 - 2e-08 34.3 3.1 0.17 12.4 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KXX78961.1 - 5.5e-07 29.7 2.7 0.066 13.6 0.0 4.2 3 1 0 4 4 4 2 Ankyrin repeats (many copies) TPR_12 PF13424.6 KXX78961.1 - 0.0014 18.9 0.6 0.0051 17.1 0.6 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2151 PF10221.9 KXX78961.1 - 0.33 9.5 1.3 0.38 9.3 0.5 1.5 2 0 0 2 2 2 0 Cell cycle and development regulator TPR_2 PF07719.17 KXX78961.1 - 0.72 10.1 3.5 0.84 9.9 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5634 PF18681.1 KXX78962.1 - 0.024 15.0 0.1 2.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5634) Med15_fungi PF05397.12 KXX78962.1 - 0.084 13.2 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 15 Sugar_tr PF00083.24 KXX78963.1 - 6.7e-43 147.2 7.5 1.2e-37 129.9 7.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXX78963.1 - 0.0055 15.7 13.0 0.0052 15.8 7.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EpsG PF14897.6 KXX78963.1 - 0.014 14.7 0.8 0.014 14.7 0.8 1.7 2 0 0 2 2 2 0 EpsG family DUF4501 PF14946.6 KXX78966.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) PEX11 PF05648.14 KXX78967.1 - 0.13 11.7 5.5 4.6 6.7 0.9 3.6 2 1 1 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) pPIWI_RE_Y PF18156.1 KXX78968.1 - 0.12 12.7 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y DnaJ PF00226.31 KXX78969.1 - 2.6e-19 69.1 0.4 7.2e-19 67.7 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain Prominin PF05478.11 KXX78969.1 - 6.6 4.5 6.1 3.1 5.6 4.1 1.4 1 1 0 1 1 1 0 Prominin Pkinase PF00069.25 KXX78970.1 - 3.5e-16 59.4 0.0 2.8e-15 56.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX78970.1 - 4e-10 39.4 0.0 1.3e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APG6_N PF17675.1 KXX78970.1 - 0.046 14.2 0.7 0.11 13.0 0.7 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Nup54 PF13874.6 KXX78970.1 - 0.86 9.7 3.2 2.1 8.4 3.2 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 LysM PF01476.20 KXX78971.1 - 1.9e-17 63.0 0.5 9.3e-06 25.6 0.0 4.0 4 0 0 4 4 4 3 LysM domain UPF0203 PF05254.12 KXX78971.1 - 0.019 15.2 3.0 14 6.0 0.4 3.6 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0203) HTH_Tnp_1 PF01527.20 KXX78971.1 - 0.092 13.1 0.0 47 4.4 0.0 3.1 3 0 0 3 3 3 0 Transposase MFAP1 PF06991.11 KXX78972.1 - 4.2e-75 252.3 31.8 4.2e-75 252.3 31.8 3.4 2 2 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Voldacs PF03517.13 KXX78974.1 - 4.2e-18 65.8 3.6 4.2e-18 65.8 3.6 2.3 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling PhoLip_ATPase_C PF16212.5 KXX78975.1 - 6e-71 239.1 14.4 6e-71 239.1 14.4 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXX78975.1 - 6.6e-25 86.6 1.8 3.2e-24 84.4 0.5 2.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXX78975.1 - 3.2e-13 50.5 0.0 4.5e-06 27.1 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXX78975.1 - 8.4e-13 48.2 0.0 4.5e-11 42.7 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXX78975.1 - 4.7e-08 32.8 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXX78975.1 - 0.002 17.9 0.0 0.0095 15.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXX78975.1 - 0.0085 16.5 0.1 4.7 7.6 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ADH_zinc_N_2 PF13602.6 KXX78976.1 - 4.3e-17 63.4 0.0 1.2e-16 61.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX78976.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase CRAL_TRIO PF00650.20 KXX78977.1 - 2.3e-41 141.2 0.0 3.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXX78977.1 - 3.5e-15 55.9 2.6 3.5e-15 55.9 2.6 1.6 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXX78977.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.10 KXX78978.1 - 2.2e-78 263.6 0.0 2.9e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KXX78978.1 - 5.7e-40 136.9 0.0 8.2e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Glyco_hydro_18 PF00704.28 KXX78980.1 - 3e-45 155.3 0.0 5.1e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 KXX78980.1 - 8e-29 99.9 0.5 2.5e-28 98.3 0.5 2.0 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.20 KXX78980.1 - 1.1e-08 34.9 0.0 0.003 17.6 0.0 3.2 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 KXX78980.1 - 2.5e-05 24.7 8.5 2.5e-05 24.7 8.5 3.5 2 1 0 2 2 2 1 Chitin recognition protein PAN_1 PF00024.26 KXX78984.1 - 9.4e-06 25.5 0.1 1.6e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 KXX78984.1 - 1.2e-05 24.8 0.0 3.1e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KXX78984.1 - 0.00039 20.3 0.0 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase PAN_4 PF14295.6 KXX78984.1 - 0.12 12.3 3.7 0.24 11.3 1.5 2.2 2 0 0 2 2 2 0 PAN domain PNP_UDP_1 PF01048.20 KXX78986.1 - 9.9e-14 51.2 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KXX78986.1 - 1.7e-07 31.6 0.1 6.4e-05 23.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KXX78986.1 - 7.2e-07 28.6 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KXX78986.1 - 0.0007 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX78986.1 - 0.006 17.0 0.1 0.034 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXX78986.1 - 0.0065 17.0 0.0 0.019 15.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KXX78986.1 - 0.016 14.8 0.0 0.048 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX78986.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXX78986.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_12 PF13424.6 KXX78986.1 - 0.048 14.0 0.2 9.7 6.6 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX78986.1 - 0.072 13.9 3.7 6.2 7.9 1.2 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KXX78986.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Tugs PF17840.1 KXX78986.1 - 0.08 13.1 0.9 0.31 11.2 0.9 2.0 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain FeThRed_B PF02943.15 KXX78986.1 - 0.17 11.9 1.0 0.37 10.8 1.0 1.5 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain Fungal_trans PF04082.18 KXX78987.1 - 1.9e-12 46.8 0.6 2.7e-12 46.3 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vps54 PF07928.12 KXX78988.1 - 1.3e-43 148.6 0.5 9.9e-43 145.8 0.2 2.4 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KXX78988.1 - 0.00022 20.6 0.3 0.0006 19.2 0.3 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXX78988.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF5364 PF17322.2 KXX78988.1 - 0.049 13.9 0.0 0.049 13.9 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5364) DUF3435 PF11917.8 KXX78989.1 - 0.0044 16.0 1.4 0.0061 15.6 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) E_Pc_C PF06752.12 KXX78990.1 - 0.22 11.6 0.5 0.24 11.5 0.5 1.0 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Zn_clus PF00172.18 KXX78991.1 - 1.3e-05 25.2 6.4 1.3e-05 25.2 6.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARS2 PF04959.13 KXX78991.1 - 5.3 7.4 6.8 0.39 11.1 0.7 1.9 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Homeodomain PF00046.29 KXX78992.1 - 5.1e-20 71.1 4.8 1.2e-19 69.9 4.8 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXX78992.1 - 0.0019 18.0 1.3 0.0043 16.9 0.6 2.0 2 0 0 2 2 2 1 Homeobox KN domain Tho2 PF11262.8 KXX78992.1 - 1.5 8.0 4.5 2 7.5 4.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 NAM-associated PF14303.6 KXX78992.1 - 2.7 8.7 10.6 4.5 8.0 10.6 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Fungal_trans_2 PF11951.8 KXX78993.1 - 7.5e-12 44.7 0.5 8.8e-07 28.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX78993.1 - 0.061 13.5 3.3 0.16 12.1 3.3 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ADD_DNMT3 PF17980.1 KXX78993.1 - 0.14 12.2 0.0 6.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Lung_7-TM_R PF06814.13 KXX78994.1 - 3.1e-72 243.3 18.0 3.8e-72 243.0 18.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SurA_N_3 PF13624.6 KXX78994.1 - 0.03 14.1 1.3 11 5.8 0.1 3.1 3 0 0 3 3 3 0 SurA N-terminal domain DLIC PF05783.11 KXX78994.1 - 0.2 10.5 0.0 0.52 9.1 0.0 1.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DUF4131 PF13567.6 KXX78994.1 - 0.97 9.1 14.1 3.6 7.2 2.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_28 PF02636.17 KXX78995.1 - 3.5e-80 269.4 0.0 5.1e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pro_isomerase PF00160.21 KXX78996.1 - 1.5e-45 155.3 0.0 2.5e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KXX78996.1 - 7.8e-05 22.8 0.0 0.00037 20.6 0.0 2.1 2 0 0 2 2 2 1 U-box domain Rtf2 PF04641.12 KXX78996.1 - 0.0025 17.3 0.0 0.0058 16.0 0.0 1.7 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KXX78996.1 - 0.0078 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Ank_2 PF12796.7 KXX78997.1 - 8.5e-75 247.4 2.1 1.6e-16 60.6 0.0 8.7 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX78997.1 - 1.2e-59 197.9 5.5 5.8e-08 33.1 0.0 11.9 4 1 8 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KXX78997.1 - 2.1e-55 182.9 0.6 1.9e-05 24.9 0.1 13.7 14 0 0 14 14 14 10 Ankyrin repeat Ank_3 PF13606.6 KXX78997.1 - 8.4e-50 160.9 0.0 0.00016 21.8 0.0 15.4 15 1 1 16 16 16 12 Ankyrin repeat Ank_5 PF13857.6 KXX78997.1 - 8.3e-46 153.5 8.6 1.4e-07 31.6 0.1 11.4 5 3 6 11 11 11 9 Ankyrin repeats (many copies) Hemerythrin PF01814.23 KXX78998.1 - 8.5e-11 42.6 0.1 1.2e-10 42.2 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_TAC_8 PF10666.9 KXX78998.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 MFS_1 PF07690.16 KXX78999.1 - 8.5e-39 133.5 61.9 7.7e-38 130.3 59.4 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXX78999.1 - 3 6.0 18.9 4.5 5.4 0.1 3.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family NACHT PF05729.12 KXX79001.1 - 1.2e-05 25.3 0.0 6.2e-05 23.0 0.0 2.2 2 1 0 2 2 2 1 NACHT domain ANAPC4_WD40 PF12894.7 KXX79001.1 - 2.8e-05 24.3 0.0 2.2 8.6 0.0 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX79001.1 - 8.6e-05 23.2 0.1 0.0072 17.2 0.0 3.7 2 0 0 2 2 2 1 WD domain, G-beta repeat PGAP1 PF07819.13 KXX79001.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXX79001.1 - 0.00021 22.0 0.3 0.00093 19.9 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXX79001.1 - 0.0042 16.6 0.0 0.0099 15.4 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NB-ARC PF00931.22 KXX79001.1 - 0.033 13.4 0.1 0.13 11.4 0.1 1.9 1 1 0 1 1 1 0 NB-ARC domain HET PF06985.11 KXX79002.1 - 2e-28 99.6 0.0 3.6e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 KXX79003.1 - 1.4e-19 70.9 0.0 2.7e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX79003.1 - 0.00023 21.6 0.0 0.00065 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX79003.1 - 0.0021 18.4 0.1 0.0082 16.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain Hydin_ADK PF17213.3 KXX79003.1 - 0.0099 16.2 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_5 PF07728.14 KXX79003.1 - 0.025 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KXX79003.1 - 0.057 12.7 0.2 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.12 KXX79003.1 - 0.058 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXX79003.1 - 0.064 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXX79003.1 - 0.072 13.6 0.0 0.46 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KXX79003.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RRM_occluded PF16842.5 KXX79004.1 - 0.062 13.2 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif PEP_mutase PF13714.6 KXX79005.1 - 3.8e-40 137.8 4.0 4.4e-40 137.6 4.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXX79005.1 - 9.3e-18 64.0 1.3 1.4e-17 63.4 1.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family BMC PF00936.19 KXX79005.1 - 1.2 9.1 5.9 1.2 9.1 2.8 2.3 2 0 0 2 2 2 0 BMC domain DUF1899 PF08953.11 KXX79006.1 - 5.7e-36 122.2 0.1 1e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KXX79006.1 - 1.3e-19 69.8 0.1 3.3e-19 68.5 0.1 1.8 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KXX79006.1 - 3.9e-16 59.2 4.3 0.00049 20.9 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79006.1 - 1.6e-07 31.6 0.0 0.0012 19.1 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX79006.1 - 0.0037 16.0 0.6 0.14 10.7 0.3 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXX79006.1 - 0.0059 15.6 0.0 0.53 9.2 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXX79006.1 - 0.0077 16.1 0.0 0.095 12.6 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A SlyX PF04102.12 KXX79006.1 - 0.009 16.6 6.7 0.024 15.2 3.7 2.3 2 0 0 2 2 2 1 SlyX Frtz PF11768.8 KXX79006.1 - 0.05 11.9 0.0 0.15 10.3 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ank_2 PF12796.7 KXX79008.1 - 1.7e-17 63.7 1.8 3.3e-05 24.4 0.0 5.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX79008.1 - 3.7e-15 56.1 0.0 7.7e-05 23.2 0.0 5.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 KXX79008.1 - 2.9e-10 40.3 0.1 1.7e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX79008.1 - 8e-06 26.3 0.7 0.00035 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX79008.1 - 1.7e-05 25.1 1.2 0.00021 21.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain Ank_5 PF13857.6 KXX79008.1 - 2.7e-05 24.4 1.5 0.53 10.7 0.1 4.9 2 2 3 5 5 5 2 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 KXX79008.1 - 0.00042 19.6 0.3 0.062 12.5 0.0 2.9 3 0 0 3 3 3 1 KAP family P-loop domain TAFA PF12020.8 KXX79008.1 - 0.014 15.8 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 TAFA family Helo_like_N PF17111.5 KXX79008.1 - 0.015 14.7 0.3 0.029 13.7 0.3 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Zeta_toxin PF06414.12 KXX79009.1 - 1.7e-15 56.9 0.0 4.8e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 KXX79009.1 - 0.0013 19.0 0.0 0.0024 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX79009.1 - 0.0016 18.9 0.1 0.0025 18.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 KXX79009.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 KXX79009.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KXX79009.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 KXX79009.1 - 0.084 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KXX79009.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 KXX79009.1 - 0.18 12.4 0.0 0.28 11.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KXX79009.1 - 0.23 11.0 0.0 3.6 7.1 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.25 KXX79010.1 - 1.5e-62 211.3 0.0 2.2e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79010.1 - 1.1e-30 106.8 0.0 2.4e-30 105.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX79010.1 - 3.3e-05 23.4 0.0 6.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXX79010.1 - 0.0044 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXX79010.1 - 0.05 12.5 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KXX79010.1 - 0.085 12.8 0.0 0.085 12.8 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family LCD1 PF09798.9 KXX79010.1 - 0.14 10.7 3.3 0.18 10.3 1.2 1.8 2 0 0 2 2 2 0 DNA damage checkpoint protein Aminotran_3 PF00202.21 KXX79011.1 - 7.8e-119 396.9 0.0 8.9e-119 396.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KXX79011.1 - 0.00059 19.2 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXX79011.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_transf_22 PF03901.17 KXX79012.1 - 2.3e-78 264.3 16.7 2.7e-78 264.1 16.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MFS_1 PF07690.16 KXX79013.1 - 2.6e-33 115.4 26.6 9.7e-33 113.5 27.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.22 KXX79013.1 - 0.46 9.5 35.0 0.013 14.6 12.3 2.6 2 1 0 2 2 2 0 Acyltransferase family DUF3543 PF12063.8 KXX79014.1 - 2.9e-96 321.7 1.5 4.7e-96 321.0 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KXX79014.1 - 1.4e-61 208.2 0.0 2.8e-61 207.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79014.1 - 5.3e-41 140.6 0.0 1.1e-40 139.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KXX79014.1 - 0.042 14.0 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC1 family IBB PF01749.20 KXX79014.1 - 7.8 7.0 9.1 2.9 8.4 3.6 2.8 1 1 1 2 2 2 0 Importin beta binding domain RhoGAP PF00620.27 KXX79015.1 - 1.5e-38 132.0 0.0 2.5e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Nup188_C PF18378.1 KXX79017.1 - 1.8e-142 474.6 0.0 2.8e-142 474.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KXX79017.1 - 1.2e-54 185.6 0.0 8.7e-39 133.2 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 zf-Tim10_DDP PF02953.15 KXX79018.1 - 2.9e-18 65.3 0.9 3.8e-18 64.9 0.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HATPase_c_5 PF14501.6 KXX79018.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 GHKL domain Use1 PF09753.9 KXX79019.1 - 2.3e-07 30.8 3.8 3.7e-07 30.1 1.2 2.1 1 1 1 2 2 2 1 Membrane fusion protein Use1 DUF3347 PF11827.8 KXX79019.1 - 0.24 11.6 5.1 6.3 6.9 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Phage_Gp23 PF10669.9 KXX79019.1 - 0.46 10.8 4.2 3 8.2 0.8 3.1 2 2 1 3 3 3 0 Protein gp23 (Bacteriophage A118) Lin-8 PF03353.15 KXX79019.1 - 1.3 8.5 5.0 1.6 8.2 5.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TBCC_N PF16752.5 KXX79019.1 - 1.9 8.9 8.6 1.6 9.2 4.0 2.3 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain GREB1 PF15782.5 KXX79019.1 - 4.5 4.3 13.3 5.6 3.9 13.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IGPS PF00218.21 KXX79020.1 - 7.3e-98 326.8 0.0 1.1e-97 326.2 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KXX79020.1 - 8.1e-49 166.0 0.0 4.4e-43 147.3 0.0 2.6 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KXX79020.1 - 1.5e-46 158.6 0.0 2.5e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXX79020.1 - 7.2e-05 22.6 0.5 0.00071 19.4 0.5 2.4 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KXX79020.1 - 0.013 15.3 0.1 0.12 12.1 0.0 2.6 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain Med5 PF08689.10 KXX79022.1 - 8.1e-88 295.5 0.0 6.8e-87 292.4 0.0 2.1 1 1 0 1 1 1 1 Mediator complex subunit Med5 B-block_TFIIIC PF04182.12 KXX79023.1 - 2.5e-16 59.6 0.0 1.5e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Pkinase_fungal PF17667.1 KXX79025.1 - 9e-54 182.8 0.0 3.2e-43 148.0 0.0 3.1 1 1 2 3 3 3 3 Fungal protein kinase Pkinase PF00069.25 KXX79025.1 - 1.7e-06 27.6 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXX79025.1 - 0.04 13.3 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXX79025.1 - 0.049 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 KXX79025.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ebp2 PF05890.12 KXX79027.1 - 1.7e-90 303.3 17.2 1.7e-90 303.3 17.2 2.0 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 HrpA_pilin PF09589.10 KXX79027.1 - 0.019 15.6 2.4 0.07 13.8 2.4 1.9 1 0 0 1 1 1 0 HrpA pilus formation protein zf-MYND PF01753.18 KXX79028.1 - 2.1e-08 34.1 19.9 5.1e-08 32.9 19.9 1.7 1 0 0 1 1 1 1 MYND finger zf-TAZ PF02135.16 KXX79028.1 - 0.73 10.3 8.0 1.3 9.5 8.0 1.4 1 0 0 1 1 1 0 TAZ zinc finger Cyanate_lyase PF02560.14 KXX79030.1 - 6.3e-29 99.6 0.0 8.8e-29 99.2 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KXX79030.1 - 2.8e-06 27.6 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KXX79030.1 - 0.0026 17.4 0.0 0.0097 15.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.22 KXX79030.1 - 0.0064 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_38 PF13936.6 KXX79030.1 - 0.039 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Kinesin PF00225.23 KXX79031.1 - 5.1e-113 377.4 0.0 6.5e-113 377.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXX79031.1 - 9.2e-27 93.8 0.0 1.6e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding YabA PF06156.13 KXX79031.1 - 0.043 14.5 0.8 19 6.0 0.1 3.0 2 0 0 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 KXX79031.1 - 0.19 10.5 2.8 0.32 9.8 2.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF87 PF01935.17 KXX79031.1 - 0.78 9.8 0.0 0.78 9.8 0.0 3.1 3 1 0 3 3 3 0 Helicase HerA, central domain PUL PF08324.11 KXX79032.1 - 1e-55 188.9 0.0 1.4e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KXX79032.1 - 2e-33 115.4 0.0 3.3e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KXX79032.1 - 7e-13 48.5 0.0 1.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXX79032.1 - 0.0022 18.5 0.2 0.019 15.4 0.2 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KXX79032.1 - 0.0048 16.7 0.0 0.0097 15.8 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 KXX79032.1 - 0.022 14.7 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KXX79032.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.6 KXX79032.1 - 0.091 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain GDA1_CD39 PF01150.17 KXX79033.1 - 2.7e-92 309.6 0.0 3.3e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_lid_2 PF17863.1 KXX79034.1 - 1.8e-10 40.5 0.2 4.8e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KXX79034.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cation_efflux PF01545.21 KXX79035.1 - 2.1e-09 37.4 11.3 3.2e-09 36.8 11.3 1.2 1 0 0 1 1 1 1 Cation efflux family PIG-Y PF15159.6 KXX79036.1 - 3.5e-22 79.1 8.4 5.1e-22 78.6 8.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Peptidase_M16_C PF05193.21 KXX79037.1 - 5.5e-18 65.6 0.0 1.6e-14 54.3 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXX79037.1 - 2.2e-05 24.5 0.0 6.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KXX79037.1 - 0.028 13.5 2.0 0.15 11.2 2.0 2.0 1 1 0 1 1 1 0 Peptidase M16C associated DGF-1_5 PF11038.8 KXX79037.1 - 0.038 13.3 0.2 0.061 12.6 0.2 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 TRAP_alpha PF03896.16 KXX79038.1 - 2.6e-06 26.8 0.1 6.7e-06 25.5 0.1 1.8 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF3955 PF13127.6 KXX79039.1 - 8.2e-15 54.4 2.8 8.2e-15 54.4 2.8 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) EamA PF00892.20 KXX79039.1 - 3.9e-09 36.8 34.5 2.1e-06 28.0 3.2 3.1 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KXX79039.1 - 3e-06 26.7 1.0 3e-06 26.7 1.0 2.1 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 KXX79039.1 - 0.00024 20.7 11.5 0.00024 20.7 11.5 1.9 2 0 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 KXX79039.1 - 0.00025 20.3 10.3 0.00042 19.6 10.3 1.3 1 0 0 1 1 1 1 UAA transporter family Spb1_C PF07780.12 KXX79040.1 - 5.8e-88 294.0 22.2 5.8e-88 294.0 22.2 3.4 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KXX79040.1 - 1.1e-56 191.7 0.0 1.9e-56 190.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KXX79040.1 - 4.6e-52 176.1 11.8 4.6e-52 176.1 11.8 4.9 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 KXX79040.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F WD40 PF00400.32 KXX79041.1 - 2.6e-15 56.5 1.5 0.053 14.4 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79041.1 - 3e-07 30.6 0.0 0.0025 18.1 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Sterol-sensing PF12349.8 KXX79042.1 - 1.7e-36 125.4 4.6 1.7e-36 125.4 4.6 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXX79042.1 - 1.6e-07 29.9 0.8 2.3e-07 29.3 0.8 1.2 1 0 0 1 1 1 1 Patched family Cupin_8 PF13621.6 KXX79043.1 - 4.3e-69 233.1 0.0 5.7e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXX79043.1 - 3.5e-05 23.4 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein 14-3-3 PF00244.20 KXX79044.1 - 9.3e-08 31.8 0.0 4.3e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein HemY_N PF07219.13 KXX79044.1 - 0.1 12.8 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 HemY protein N-terminus FMN_dh PF01070.18 KXX79045.1 - 4.5e-100 335.1 0.0 1.6e-99 333.2 0.0 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXX79045.1 - 3e-17 62.5 0.0 5.5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXX79045.1 - 0.00011 21.4 0.1 0.00019 20.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXX79045.1 - 0.0086 15.1 4.4 0.066 12.2 0.3 3.0 1 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KXX79045.1 - 0.077 12.2 0.1 8.9 5.4 0.1 2.4 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NMO PF03060.15 KXX79045.1 - 0.19 11.1 0.7 0.34 10.3 0.7 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DUF4202 PF13875.6 KXX79046.1 - 6.4e-79 264.2 0.2 7.2e-79 264.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Dynamin_N PF00350.23 KXX79047.1 - 1.1e-42 146.0 0.1 2.5e-42 144.8 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KXX79047.1 - 4.9e-07 29.3 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KXX79047.1 - 1.1e-05 25.5 0.0 0.00016 21.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXX79047.1 - 0.006 17.0 0.2 0.033 14.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 KXX79047.1 - 0.039 13.7 0.3 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KXX79047.1 - 0.049 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system GATase_4 PF13230.6 KXX79048.1 - 2.5e-16 59.4 0.0 7.9e-14 51.2 0.0 2.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KXX79048.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Ras PF00071.22 KXX79049.1 - 7.4e-57 191.5 0.0 8.8e-57 191.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX79049.1 - 8.8e-32 109.8 0.0 1.2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX79049.1 - 1.6e-13 50.4 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXX79049.1 - 2.7e-08 33.9 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXX79049.1 - 5.3e-07 29.2 0.0 6.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXX79049.1 - 1.9e-05 24.3 0.1 0.00058 19.5 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXX79049.1 - 7.3e-05 22.7 0.1 0.0036 17.2 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 KXX79049.1 - 0.0019 17.7 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KXX79049.1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KXX79049.1 - 0.0061 16.3 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KXX79049.1 - 0.0068 16.2 0.2 0.21 11.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KXX79049.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX79049.1 - 0.015 15.7 0.1 0.035 14.5 0.0 1.7 1 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KXX79049.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KXX79049.1 - 0.021 14.1 0.3 0.048 12.9 0.0 1.7 3 0 0 3 3 3 0 Septin AAA_7 PF12775.7 KXX79049.1 - 0.026 14.0 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KXX79049.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KXX79049.1 - 0.052 12.7 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KXX79049.1 - 0.059 13.3 0.2 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KXX79049.1 - 0.069 13.5 0.1 0.32 11.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase TniB PF05621.11 KXX79049.1 - 0.11 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 KXX79049.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KXX79049.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 KXX79049.1 - 0.14 12.0 1.3 1.5 8.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DAP3 PF10236.9 KXX79049.1 - 0.16 11.1 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FAD_binding_3 PF01494.19 KXX79053.1 - 1.2e-10 41.2 0.1 5e-10 39.2 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXX79053.1 - 0.0019 17.3 0.0 0.0088 15.1 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Mem_trans PF03547.18 KXX79054.1 - 3.9e-15 55.1 7.0 2.2e-08 32.9 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein DUF4059 PF13268.6 KXX79054.1 - 0.16 12.4 2.2 2.9 8.3 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) DUF2975 PF11188.8 KXX79054.1 - 1.4 8.8 9.1 0.18 11.7 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) p450 PF00067.22 KXX79056.1 - 3.8e-26 91.9 0.0 5.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 KXX79057.1 - 3.4e-09 36.9 0.0 5.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX79057.1 - 0.0019 17.8 0.0 0.01 15.4 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family HET PF06985.11 KXX79059.1 - 7.5e-15 55.6 4.0 3.7e-12 46.8 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MoaC PF01967.21 KXX79060.1 - 6.2e-55 185.0 2.3 9.3e-55 184.4 2.3 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KXX79060.1 - 6.8e-35 119.8 0.0 4.8e-34 117.0 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KXX79060.1 - 1.7e-25 90.4 0.0 3.2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXX79060.1 - 3.3e-05 24.2 0.0 0.00072 19.8 0.0 2.4 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KXX79060.1 - 0.021 14.9 0.0 2.9 8.0 0.0 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain ANAPC4_WD40 PF12894.7 KXX79061.1 - 1.5e-07 31.6 0.0 0.1 12.9 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX79061.1 - 0.00037 21.2 12.0 18 6.4 0.2 6.8 5 1 1 6 6 6 1 WD domain, G-beta repeat IKI3 PF04762.12 KXX79061.1 - 0.025 12.6 0.1 3.3 5.6 0.0 3.0 3 1 1 4 4 4 0 IKI3 family PD40 PF07676.12 KXX79061.1 - 0.028 14.4 0.7 1.1 9.3 0.1 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat FYVE PF01363.21 KXX79062.1 - 1.4e-15 57.2 7.8 2.3e-15 56.4 7.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KXX79062.1 - 0.56 10.4 13.8 0.21 11.8 9.3 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger Synaptobrevin PF00957.21 KXX79063.1 - 9.6e-15 54.1 0.6 1.5e-14 53.5 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXX79063.1 - 1.2e-09 38.1 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain TPP_enzyme_N PF02776.18 KXX79063.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Herpes_teg_N PF04843.12 KXX79063.1 - 0.074 12.7 0.1 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region DUF742 PF05331.11 KXX79063.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Adenylsucc_synt PF00709.21 KXX79064.1 - 1.1e-163 545.0 0.1 1.3e-163 544.9 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PhageP22-tail PF09251.10 KXX79064.1 - 0.1 10.9 0.0 0.17 10.2 0.0 1.3 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike ELO PF01151.18 KXX79065.1 - 3.6e-80 269.1 11.0 4.6e-80 268.8 11.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family BatD PF13584.6 KXX79065.1 - 0.036 12.9 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF3760 PF12586.8 KXX79065.1 - 2.2 8.5 4.4 0.5 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) VASt PF16016.5 KXX79066.1 - 4.8e-35 121.2 1.1 8.6e-35 120.4 1.1 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KXX79066.1 - 6.4e-11 42.4 0.0 3e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KXX79066.1 - 4e-05 24.1 0.1 9.8e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 KXX79066.1 - 0.076 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 GRAM domain GRASP55_65 PF04495.14 KXX79067.1 - 0.19 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Adap_comp_sub PF00928.21 KXX79068.1 - 5.3e-18 65.3 0.1 7.5e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXX79068.1 - 1.9e-07 31.1 0.1 3e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KXX79068.1 - 0.023 15.1 1.1 0.038 14.4 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) ANAPC4 PF12896.7 KXX79069.1 - 5e-68 228.6 0.0 7.3e-68 228.1 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KXX79069.1 - 4e-14 52.7 0.2 4e-13 49.5 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX79069.1 - 0.082 13.8 0.0 0.86 10.6 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat FAD_binding_4 PF01565.23 KXX79070.1 - 3.6e-25 88.3 0.0 6.4e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXX79070.1 - 3.1e-13 49.9 0.1 1.1e-12 48.1 0.1 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain SET PF00856.28 KXX79072.1 - 1e-08 35.7 0.0 2.4e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 SET domain p450 PF00067.22 KXX79074.1 - 3.8e-23 82.0 0.0 4.6e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 KXX79075.1 - 6.3e-13 49.7 0.8 1.2e-12 48.8 0.8 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX79075.1 - 5.2e-05 23.5 0.1 0.00035 20.8 0.1 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 KXX79076.1 - 7.8e-13 48.0 0.0 3.9e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.31 KXX79077.1 - 1.8e-16 60.5 0.0 7.5e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXX79077.1 - 0.0071 15.6 0.0 0.0089 15.3 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF3074 PF11274.8 KXX79078.1 - 1.3e-54 185.0 3.6 4.4e-54 183.2 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 KXX79078.1 - 0.0015 17.9 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 START domain Exonuc_VII_L PF02601.15 KXX79078.1 - 9.2 5.7 18.2 19 4.7 18.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mg_trans_NIPA PF05653.14 KXX79080.1 - 2.1e-95 319.2 14.2 2.5e-95 319.0 14.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXX79080.1 - 3.6e-05 24.0 6.7 3.6e-05 24.0 6.7 2.5 3 0 0 3 3 3 2 EamA-like transporter family DUF4293 PF14126.6 KXX79080.1 - 1.7 8.9 6.0 3.8 7.8 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Phage_holin_1 PF04531.13 KXX79080.1 - 3.8 8.1 6.0 27 5.4 0.2 3.0 3 1 0 3 3 3 0 Bacteriophage holin Transgly_assoc PF04226.13 KXX79080.1 - 7.1 7.0 8.9 1.1 9.6 2.5 2.9 3 0 0 3 3 3 0 Transglycosylase associated protein DUF1295 PF06966.12 KXX79081.1 - 1.3e-32 113.2 0.0 1.5e-31 109.7 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KXX79081.1 - 1.2e-05 25.3 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KXX79081.1 - 0.0005 20.4 0.0 0.0014 19.0 0.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KXX79081.1 - 0.0051 15.6 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KXX79081.1 - 0.0095 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FAM150 PF15129.6 KXX79082.1 - 0.031 14.4 0.0 9.8 6.4 0.0 2.4 2 0 0 2 2 2 0 FAM150 family GST_N PF02798.20 KXX79083.1 - 2.9e-15 56.4 0.0 7e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXX79083.1 - 1.6e-12 47.5 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX79083.1 - 4.4e-10 39.8 0.0 8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX79083.1 - 6.5e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXX79083.1 - 4.7e-09 36.3 0.0 7.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXX79083.1 - 1.8e-07 31.1 0.1 3.2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXX79083.1 - 0.0015 19.1 0.0 0.028 15.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KXX79084.1 - 2.3e-38 132.0 54.2 2.3e-38 132.0 54.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_23 PF13489.6 KXX79085.1 - 2.8e-19 69.5 0.0 4.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX79085.1 - 2.3e-11 44.3 0.0 9.9e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX79085.1 - 3.9e-10 40.2 0.0 9.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX79085.1 - 2.3e-06 28.3 0.0 8.9e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX79085.1 - 3.3e-06 27.0 0.0 9e-05 22.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX79085.1 - 8.6e-05 22.0 0.0 0.00094 18.6 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX79085.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KXX79085.1 - 0.08 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KXX79085.1 - 0.087 12.3 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 KXX79085.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXX79085.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Hydrolase_6 PF13344.6 KXX79087.1 - 5.1e-21 74.7 0.0 9.7e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXX79087.1 - 2.2e-19 69.3 0.0 4.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXX79087.1 - 0.022 15.0 0.0 0.57 10.4 0.0 2.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXX79087.1 - 0.055 13.5 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.21 KXX79088.1 - 3.2e-55 187.4 0.0 1e-54 185.7 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family GST_N_3 PF13417.6 KXX79089.1 - 1.9e-16 60.2 0.0 4.8e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX79089.1 - 4.1e-16 59.0 0.0 7.8e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXX79089.1 - 8.7e-08 32.4 0.0 3.2e-07 30.6 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXX79089.1 - 1e-06 29.3 0.0 1.8e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXX79089.1 - 4.3e-05 23.5 1.6 7.1e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX79089.1 - 0.001 19.3 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX79089.1 - 0.0017 18.5 0.1 0.0066 16.6 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Spt20 PF12090.8 KXX79089.1 - 0.35 10.4 2.6 0.78 9.3 2.6 1.6 1 0 0 1 1 1 0 Spt20 family RIC1 PF07064.13 KXX79090.1 - 2.2e-94 315.6 0.1 3.6e-94 314.9 0.1 1.4 1 0 0 1 1 1 1 RIC1 PD40 PF07676.12 KXX79090.1 - 0.0084 16.0 0.4 0.23 11.4 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 KXX79091.1 - 3.4e-18 65.7 5.0 6.8e-05 23.6 0.2 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79091.1 - 2.1e-13 50.4 0.0 0.17 12.2 0.0 5.7 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX79091.1 - 0.0072 15.0 0.0 0.033 12.9 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF1513 PF07433.11 KXX79091.1 - 0.0093 15.1 0.0 0.088 11.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KXX79091.1 - 0.022 13.3 0.0 1.8 7.0 0.0 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain Frtz PF11768.8 KXX79091.1 - 0.083 11.2 0.0 0.22 9.8 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Fungal_trans PF04082.18 KXX79092.1 - 3.3e-18 65.7 0.1 1.1e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX79092.1 - 2.5e-08 33.9 8.7 2.5e-08 33.9 8.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hep_59 PF07052.11 KXX79093.1 - 4.4e-20 72.4 1.5 4.4e-20 72.4 1.5 2.8 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 FlgT_M PF16539.5 KXX79093.1 - 0.0021 18.2 3.0 0.0021 18.2 3.0 2.1 3 0 0 3 3 3 1 Flagellar assembly protein T, middle domain DMAP_binding PF06464.11 KXX79093.1 - 0.039 14.8 0.3 0.039 14.8 0.3 3.1 3 0 0 3 3 3 0 DMAP1-binding Domain SKG6 PF08693.10 KXX79094.1 - 0.00049 19.5 3.0 0.001 18.5 3.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 KXX79094.1 - 0.027 14.4 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Got1 PF04178.12 KXX79095.1 - 1.4e-33 115.6 15.4 2.2e-33 115.0 15.4 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family HLH PF00010.26 KXX79096.1 - 3.6e-12 46.0 0.0 1.6e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.19 KXX79096.1 - 0.018 15.6 1.3 0.77 10.4 0.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein NPR3 PF03666.13 KXX79097.1 - 5.8e-153 510.0 0.0 7.7e-153 509.6 0.0 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SARAF PF06682.12 KXX79097.1 - 7.6 6.1 8.2 0.75 9.4 2.1 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Choline_kinase PF01633.20 KXX79098.1 - 2.1e-54 184.3 0.0 2e-53 181.1 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KXX79098.1 - 9.9e-11 42.0 1.0 3e-10 40.5 1.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXX79098.1 - 0.026 13.8 0.0 0.92 8.8 0.0 2.3 2 0 0 2 2 2 0 Ecdysteroid kinase WD40 PF00400.32 KXX79099.1 - 4.6e-15 55.7 10.5 0.0077 17.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79099.1 - 2.8e-07 30.7 0.3 0.0012 19.1 0.3 4.2 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX79099.1 - 3.4e-05 22.7 4.3 5e-05 22.2 2.0 2.2 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXX79099.1 - 0.0024 16.7 0.1 5.6 5.6 0.0 3.1 1 1 0 2 2 2 2 Nup133 N terminal like Dicty_REP PF05086.12 KXX79100.1 - 4.2 5.2 5.0 6.4 4.6 5.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HpcH_HpaI PF03328.14 KXX79101.1 - 9.5e-40 136.1 0.0 1.5e-39 135.4 0.0 1.3 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KXX79101.1 - 2e-05 23.9 0.0 5.8e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold HTH_38 PF13936.6 KXX79102.1 - 0.00033 20.3 0.5 0.011 15.4 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KXX79102.1 - 0.002 17.8 0.9 0.026 14.3 0.3 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KXX79102.1 - 0.013 15.7 0.1 0.21 11.8 0.0 2.8 2 1 0 2 2 2 0 Transposase HTH_32 PF13565.6 KXX79102.1 - 0.063 13.9 1.5 0.84 10.3 0.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KXX79102.1 - 0.066 13.0 0.2 0.18 11.6 0.2 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 KXX79102.1 - 0.19 11.6 0.1 4.1 7.3 0.0 2.8 3 1 0 3 3 3 0 Bacterial regulatory protein, arsR family Sugar_tr PF00083.24 KXX79103.1 - 8.8e-32 110.5 31.4 2.9e-19 69.3 7.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXX79103.1 - 7.4e-23 81.0 24.2 3.7e-17 62.3 12.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KXX79103.1 - 2.8 7.6 14.7 1.1 9.0 1.3 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Acetate_kinase PF00871.17 KXX79104.1 - 2.7e-85 286.5 0.0 3.2e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1908 PF08926.11 KXX79105.1 - 0.051 12.7 1.0 0.077 12.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) MSP1a PF11670.8 KXX79106.1 - 0.042 13.1 0.9 2.8 7.2 0.2 2.6 1 1 0 2 2 2 0 Major surface protein 1a (MSP1a) zf-C2H2 PF00096.26 KXX79107.1 - 5.8e-05 23.3 10.5 0.0027 18.1 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX79107.1 - 0.014 16.2 8.8 0.16 12.9 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXX79107.1 - 0.024 15.1 1.8 0.024 15.1 1.8 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Nup160 PF11715.8 KXX79107.1 - 0.026 13.2 0.2 0.035 12.8 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 zf-C2H2_8 PF15909.5 KXX79107.1 - 0.05 13.9 4.9 0.91 9.9 1.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc ribbon DUF3439 PF11921.8 KXX79107.1 - 0.072 13.1 2.6 0.15 12.0 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-met PF12874.7 KXX79107.1 - 1.1 9.8 6.2 5.8 7.4 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KXX79107.1 - 2 9.1 5.8 4.7 8.0 0.8 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger AAA PF00004.29 KXX79109.1 - 1.7e-29 102.9 0.0 1.1e-10 42.0 0.0 3.6 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KXX79109.1 - 5.4e-19 68.1 4.8 1.6e-06 28.2 0.8 3.8 3 0 0 3 3 3 3 AAA lid domain Viral_helicase1 PF01443.18 KXX79109.1 - 1.3e-09 38.1 0.0 0.0061 16.3 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KXX79109.1 - 6.7e-08 32.5 0.0 0.00017 21.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KXX79109.1 - 4.7e-07 29.4 0.0 0.17 11.3 0.0 3.9 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXX79109.1 - 8.7e-07 29.0 0.1 0.11 12.5 0.0 3.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX79109.1 - 1.1e-06 29.0 4.8 1 9.6 0.3 5.5 3 3 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KXX79109.1 - 4.7e-06 26.8 0.0 0.11 12.7 0.0 3.3 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KXX79109.1 - 1.5e-05 24.8 0.0 3 7.5 0.0 3.8 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXX79109.1 - 5.2e-05 23.8 0.2 0.76 10.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXX79109.1 - 0.0003 21.2 0.5 0.43 10.9 0.0 3.7 4 0 0 4 4 3 1 AAA ATPase domain AAA_28 PF13521.6 KXX79109.1 - 0.00051 20.3 0.4 1.6 8.9 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KXX79109.1 - 0.0016 18.8 3.2 2.5 8.4 0.2 4.0 4 2 2 6 6 4 2 AAA domain AAA_7 PF12775.7 KXX79109.1 - 0.0025 17.3 0.4 1.7 8.1 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXX79109.1 - 0.0072 16.1 0.1 23 4.6 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 KXX79109.1 - 0.013 15.2 3.3 1.9 8.2 0.8 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXX79109.1 - 0.024 15.0 0.1 10 6.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Torsin PF06309.11 KXX79109.1 - 0.032 14.3 0.1 22 5.2 0.0 3.5 3 0 0 3 3 3 0 Torsin SRP54 PF00448.22 KXX79109.1 - 0.072 12.7 1.5 5.5 6.6 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CDC27 PF09507.10 KXX79109.1 - 0.26 10.6 30.4 0.39 10.0 30.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_17 PF13207.6 KXX79109.1 - 0.48 10.8 12.9 0.21 12.0 0.1 3.7 5 0 0 5 5 2 0 AAA domain Peptidase_S64 PF08192.11 KXX79109.1 - 2.9 6.3 6.3 5.4 5.4 6.3 1.5 1 0 0 1 1 1 0 Peptidase family S64 La PF05383.17 KXX79110.1 - 6e-18 64.7 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 La domain HLH PF00010.26 KXX79111.1 - 4.7e-07 29.7 0.1 9e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.6 KXX79111.1 - 0.019 15.8 0.2 0.059 14.2 0.0 1.9 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 GCV_T PF01571.21 KXX79112.1 - 6.7e-85 284.5 0.0 8.6e-85 284.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KXX79112.1 - 2.1e-19 69.2 0.1 5.5e-19 67.9 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HA2 PF04408.23 KXX79113.1 - 1.4e-22 80.0 0.6 5.4e-22 78.1 0.0 2.3 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXX79113.1 - 8.5e-17 61.3 0.0 2.3e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXX79113.1 - 3e-13 50.1 0.0 6.7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX79113.1 - 3.8e-08 33.3 0.1 8.7e-08 32.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXX79113.1 - 3.2e-05 24.2 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXX79113.1 - 8.1e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KXX79113.1 - 0.00014 22.3 0.0 0.00032 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXX79113.1 - 0.00022 21.0 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXX79113.1 - 0.0023 17.6 0.2 0.0054 16.4 0.2 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 KXX79113.1 - 0.0031 17.5 0.0 0.89 9.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KXX79113.1 - 0.0043 17.0 0.1 0.0078 16.2 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ATPase PF06745.13 KXX79113.1 - 0.0084 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 KXX79113.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KXX79113.1 - 0.079 13.0 0.2 0.51 10.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KXX79113.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KXX79113.1 - 0.084 13.2 0.1 0.3 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 KXX79113.1 - 0.13 12.8 0.2 0.49 10.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Pam16 PF03656.13 KXX79113.1 - 1.8 8.6 5.9 0.31 11.1 1.3 2.1 2 0 0 2 2 2 0 Pam16 EF-hand_1 PF00036.32 KXX79114.1 - 1.8e-26 89.7 7.4 1.1e-06 27.7 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KXX79114.1 - 2.5e-22 76.8 7.4 6.8e-05 22.5 0.2 5.4 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 KXX79114.1 - 8.5e-22 77.4 7.9 7.2e-10 39.2 0.0 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KXX79114.1 - 6.7e-20 70.7 10.2 6.6e-10 38.7 0.0 5.1 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KXX79114.1 - 1.6e-16 59.0 4.6 0.00045 19.6 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_10 PF14788.6 KXX79114.1 - 0.048 13.5 0.2 11 6.0 0.0 3.0 2 1 1 3 3 3 0 EF hand EF-hand_9 PF14658.6 KXX79114.1 - 0.062 13.6 0.4 1.8 8.9 0.0 2.9 3 1 0 3 3 3 0 EF-hand domain RRM_1 PF00076.22 KXX79115.1 - 5.4e-24 83.8 0.1 7.2e-24 83.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX79115.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KXX79115.1 - 0.051 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KXX79115.1 - 0.067 13.2 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif DbpA PF03880.15 KXX79115.1 - 0.094 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain DUF846 PF05832.12 KXX79116.1 - 4.9e-52 175.6 8.8 5.9e-52 175.4 8.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5504 PF17608.2 KXX79116.1 - 0.02 15.0 0.8 0.02 15.0 0.8 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5504) TctB PF07331.11 KXX79116.1 - 2.4 8.4 14.4 2.4 8.4 4.0 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family ChaC PF04752.12 KXX79117.1 - 8.1e-54 182.4 0.0 1e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Glyco_hydro_77 PF02446.17 KXX79117.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase Serine_rich PF08824.10 KXX79118.1 - 0.026 14.5 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain RNA_POL_M_15KD PF02150.16 KXX79119.1 - 6.8e-10 38.7 5.3 6.8e-10 38.7 5.3 3.4 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KXX79119.1 - 7.5e-10 38.5 6.4 7.5e-10 38.5 6.4 4.8 4 2 0 4 4 4 1 Transcription factor S-II (TFIIS) RRM_9 PF18444.1 KXX79119.1 - 0.054 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif zf-CHY PF05495.12 KXX79119.1 - 0.15 12.5 0.6 0.15 12.5 0.6 3.5 3 1 0 3 3 3 0 CHY zinc finger GPR15L PF15854.5 KXX79119.1 - 6.4 7.1 7.4 0.39 11.0 0.3 2.3 3 0 0 3 3 3 0 G-protein coupled receptor ligand 15 Lar_restr_allev PF14354.6 KXX79119.1 - 8.4 6.9 15.3 0.24 11.8 1.1 3.4 2 1 1 3 3 3 0 Restriction alleviation protein Lar Rotamase PF00639.21 KXX79120.1 - 5.5e-21 75.3 0.0 7.8e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KXX79120.1 - 5.7e-16 59.1 0.0 7.8e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KXX79120.1 - 1.4e-07 31.4 1.0 3e-07 30.4 1.0 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 KXX79120.1 - 0.00073 20.4 0.0 0.0011 19.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.23 KXX79120.1 - 0.096 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu SET PF00856.28 KXX79121.1 - 1.3e-09 38.7 0.3 9.6e-09 35.9 0.1 2.4 2 1 0 2 2 2 1 SET domain Tmemb_55A PF09788.9 KXX79121.1 - 0.043 12.9 0.2 0.092 11.8 0.2 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A FAM76 PF16046.5 KXX79121.1 - 3.1 7.1 9.3 0.055 12.8 0.9 2.2 2 0 0 2 2 2 0 FAM76 protein Ribosomal_L14 PF00238.19 KXX79122.1 - 2.8e-42 143.7 4.0 3.2e-42 143.5 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF418 PF04235.12 KXX79124.1 - 1.2 9.1 9.6 0.55 10.1 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF418) BCHF PF07284.11 KXX79124.1 - 3 7.9 7.8 4 7.5 7.8 1.2 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) LrgB PF04172.16 KXX79125.1 - 2.8e-21 76.0 11.6 5.9e-21 75.0 11.6 1.5 1 0 0 1 1 1 1 LrgB-like family RecC_C PF17946.1 KXX79125.1 - 0.12 12.1 0.8 0.2 11.4 0.8 1.3 1 0 0 1 1 1 0 RecC C-terminal domain CVNH PF08881.10 KXX79126.1 - 1.7e-14 54.3 0.0 2.2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 CVNH domain FA_desaturase PF00487.24 KXX79127.1 - 5.7e-23 82.1 23.8 1.6e-22 80.6 23.8 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXX79127.1 - 8e-08 32.6 0.0 4.7e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Acetyltransf_3 PF13302.7 KXX79128.1 - 3.5e-30 105.5 0.0 4.2e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXX79128.1 - 5.3e-06 26.6 0.0 7.6e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX79128.1 - 1.8e-05 24.9 0.0 2.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KXX79128.1 - 4.6e-05 23.1 0.1 0.00027 20.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.19 KXX79129.1 - 1.1e-68 231.8 0.0 1.4e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX79129.1 - 1.3e-27 97.1 0.0 2.5e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXX79129.1 - 0.00017 21.3 0.1 0.0023 17.6 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX79129.1 - 0.00075 18.7 0.1 0.5 9.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KXX79129.1 - 0.0011 18.3 0.9 0.0043 16.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXX79129.1 - 0.0019 18.4 0.0 0.005 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX79129.1 - 0.014 14.5 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein WD40 PF00400.32 KXX79130.1 - 1.4e-39 133.3 22.1 1.5e-06 28.8 0.3 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KXX79130.1 - 1.6e-10 40.7 0.3 6.9e-10 38.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KXX79130.1 - 2.9e-09 37.1 1.5 0.052 13.8 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KXX79130.1 - 2.7e-08 33.5 0.1 1.1e-07 31.6 0.0 2.0 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.8 KXX79130.1 - 4.3e-07 29.0 1.6 0.38 9.3 0.0 4.1 3 1 1 4 4 4 4 Nucleoporin Nup120/160 F-box_4 PF15966.5 KXX79130.1 - 0.00061 19.7 0.0 0.0028 17.5 0.0 2.2 1 0 0 1 1 1 1 F-box Mito_carr PF00153.27 KXX79131.1 - 1.3e-67 223.8 1.5 9.3e-22 76.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-RING_2 PF13639.6 KXX79132.1 - 1.2e-05 25.6 6.1 4.1e-05 23.8 6.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX79132.1 - 6.4e-05 22.8 3.1 7.9e-05 22.5 1.6 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX79132.1 - 0.00011 22.4 2.9 0.0004 20.6 3.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXX79132.1 - 0.00012 21.7 0.2 0.00046 19.9 0.2 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXX79132.1 - 0.00022 21.2 6.5 0.0037 17.3 1.1 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXX79132.1 - 0.00022 21.0 3.5 0.00022 21.0 3.5 3.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX79132.1 - 0.00044 20.1 0.6 0.00044 20.1 0.6 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX79132.1 - 0.00087 19.2 3.4 0.00087 19.2 3.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXX79132.1 - 0.018 14.9 4.1 0.054 13.4 4.1 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXX79132.1 - 0.053 13.7 0.8 0.053 13.7 0.8 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXX79132.1 - 0.12 12.4 0.6 0.23 11.5 0.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 KXX79132.1 - 0.23 11.4 2.1 0.35 10.8 2.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Zn_ribbon_17 PF17120.5 KXX79132.1 - 6.7 6.4 8.5 1 9.0 2.5 2.5 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type F-box-like PF12937.7 KXX79133.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.8 1 1 0 1 1 1 0 F-box-like Acyl_transf_3 PF01757.22 KXX79134.1 - 2.5e-21 76.1 20.6 6.4e-21 74.8 20.2 1.9 1 1 0 1 1 1 1 Acyltransferase family ACC_central PF08326.12 KXX79135.1 - 1.4e-274 912.8 0.0 1.8e-274 912.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KXX79135.1 - 5.2e-185 615.8 0.0 6.8e-185 615.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KXX79135.1 - 8.3e-53 179.0 0.0 1.5e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXX79135.1 - 1.4e-27 96.4 0.1 2.9e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXX79135.1 - 8.1e-21 74.2 0.0 1.6e-18 66.8 0.0 3.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXX79135.1 - 1.3e-16 60.2 0.1 2.7e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXX79135.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KXX79135.1 - 0.0046 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXX79135.1 - 0.0095 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.22 KXX79135.1 - 0.014 15.0 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain GxGYxYP_N PF16216.5 KXX79135.1 - 0.015 15.5 0.1 0.042 14.0 0.0 1.7 2 0 0 2 2 2 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 KXX79135.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon NUDE_C PF04880.13 KXX79136.1 - 9.1e-45 153.3 10.2 9.1e-45 153.3 10.2 3.9 2 1 1 4 4 2 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KXX79136.1 - 0.0011 19.3 8.7 0.0011 19.3 8.7 4.8 2 1 2 4 4 3 1 Cell division protein ZapB Tho2 PF11262.8 KXX79136.1 - 0.015 14.5 0.7 0.015 14.5 0.7 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Chibby PF14645.6 KXX79136.1 - 0.031 14.7 11.2 0.46 10.9 1.0 2.6 1 1 1 2 2 2 0 Chibby family Fez1 PF06818.15 KXX79136.1 - 0.4 11.1 24.5 1 9.8 13.4 2.8 2 1 1 3 3 3 0 Fez1 Tropomyosin_1 PF12718.7 KXX79136.1 - 0.63 10.2 34.2 0.36 11.0 2.1 4.0 2 1 2 4 4 4 0 Tropomyosin like FPP PF05911.11 KXX79136.1 - 1 7.5 24.7 6 4.9 24.7 2.0 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 KXX79136.1 - 1.2 8.7 30.2 2.4 7.7 28.1 2.2 2 1 0 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 KXX79136.1 - 1.9 8.5 33.3 0.69 9.9 22.8 3.5 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 KXX79136.1 - 2.6 7.8 30.0 0.022 14.6 15.5 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CCDC158 PF15921.5 KXX79136.1 - 2.7 5.7 15.1 4.1 5.1 15.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 Atg14 PF10186.9 KXX79136.1 - 3.4 6.7 21.8 0.044 12.9 7.2 3.0 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 KXX79136.1 - 3.6 6.1 17.8 5.4 5.5 17.8 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 KXX79136.1 - 4 4.8 22.6 5.7 4.3 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.9 KXX79136.1 - 5.3 5.8 15.2 48 2.6 15.2 2.2 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain BTB PF00651.31 KXX79137.1 - 0.0012 19.1 0.0 0.0041 17.3 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Nbs1_C PF08599.10 KXX79139.1 - 0.54 10.4 2.5 1 9.5 2.5 1.4 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 HAUS-augmin3 PF14932.6 KXX79141.1 - 4.7e-05 23.1 7.5 4.7e-05 23.1 7.5 2.9 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 STAT_alpha PF01017.20 KXX79141.1 - 0.012 15.5 4.8 0.012 15.5 4.8 2.7 3 0 0 3 3 3 0 STAT protein, all-alpha domain Mis14 PF08641.12 KXX79141.1 - 0.018 15.4 2.7 0.018 15.4 2.7 3.3 3 1 1 4 4 4 0 Kinetochore protein Mis14 like V_ATPase_I PF01496.19 KXX79141.1 - 0.34 8.8 2.9 0.55 8.1 2.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 KXX79141.1 - 0.73 10.1 4.4 9.7 6.5 0.2 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1387 PF07139.11 KXX79142.1 - 0.94 9.2 22.0 0.35 10.6 7.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1387) MIF4G_like_2 PF09090.11 KXX79142.1 - 2.8 7.4 6.8 0.089 12.2 0.5 1.6 2 0 0 2 2 2 0 MIF4G like Glyco_hydro_76 PF03663.14 KXX79143.1 - 2.8e-146 487.7 2.5 3.3e-146 487.5 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NPV_P10 PF05531.12 KXX79144.1 - 9.4e-06 26.0 10.7 0.011 16.2 0.1 4.8 2 1 2 4 4 4 1 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 KXX79144.1 - 0.0023 18.5 21.3 1.5 9.5 0.3 5.8 2 1 4 6 6 6 1 SlyX DUF4407 PF14362.6 KXX79144.1 - 0.0043 16.5 8.9 0.0043 16.5 8.9 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) Noelin-1 PF12308.8 KXX79144.1 - 0.0044 17.0 0.2 0.0044 17.0 0.2 4.2 3 1 2 5 5 4 1 Neurogenesis glycoprotein DUF1664 PF07889.12 KXX79144.1 - 0.0052 16.8 20.4 0.32 11.0 1.7 4.6 1 1 5 6 6 6 2 Protein of unknown function (DUF1664) DUF16 PF01519.16 KXX79144.1 - 0.016 15.7 20.6 1.3 9.5 2.1 4.5 1 1 3 4 4 4 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KXX79144.1 - 0.025 15.0 20.7 0.11 13.0 1.5 5.9 5 2 2 7 7 7 0 Flagella accessory protein C (FlaC) Matrilin_ccoil PF10393.9 KXX79144.1 - 0.073 12.9 4.2 7.2 6.6 0.0 3.5 4 0 0 4 4 3 0 Trimeric coiled-coil oligomerisation domain of matrilin LPP PF04728.13 KXX79144.1 - 0.075 13.4 9.8 1.7 9.1 0.4 4.8 5 1 1 6 6 6 0 Lipoprotein leucine-zipper KxDL PF10241.9 KXX79144.1 - 0.12 12.6 10.7 0.43 10.9 0.3 4.1 2 1 2 4 4 4 0 Uncharacterized conserved protein Bacillus_HBL PF05791.11 KXX79144.1 - 0.12 12.2 2.8 2.2 8.1 0.5 2.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BRI3BP PF14965.6 KXX79144.1 - 0.17 11.4 0.4 1.5 8.3 0.0 2.6 3 0 0 3 3 3 0 Negative regulator of p53/TP53 CART PF06373.11 KXX79144.1 - 0.34 11.1 1.3 1.6 9.0 0.0 2.7 3 0 0 3 3 2 0 Cocaine and amphetamine regulated transcript protein (CART) Occludin_ELL PF07303.13 KXX79144.1 - 0.43 11.3 16.7 12 6.6 0.1 4.3 3 1 1 4 4 4 0 Occludin homology domain Exonuc_VII_L PF02601.15 KXX79144.1 - 1.3 8.5 27.1 1.1e+04 -4.4 27.1 2.9 1 1 0 1 1 0 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KXX79144.1 - 1.3 6.8 16.6 0.023 12.7 5.1 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 KXX79144.1 - 1.4 7.4 18.7 0.056 12.0 5.2 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Phage_GP20 PF06810.11 KXX79144.1 - 1.5 8.6 12.8 3.5 7.4 3.0 3.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 XhlA PF10779.9 KXX79144.1 - 1.5 9.0 29.5 2.4 8.4 1.1 6.3 3 3 3 7 7 7 0 Haemolysin XhlA Snapin_Pallidin PF14712.6 KXX79144.1 - 2.3 8.7 21.1 27 5.3 5.3 5.8 4 3 0 4 4 4 0 Snapin/Pallidin Csm1_N PF18504.1 KXX79144.1 - 2.4 8.6 26.9 5.6 7.4 0.5 6.2 5 2 1 6 6 6 0 Csm1 N-terminal domain DUF4988 PF16378.5 KXX79144.1 - 2.7 7.6 7.5 37 3.9 0.8 3.7 3 1 1 4 4 4 0 Domain of unknown function FliD_C PF07195.12 KXX79144.1 - 2.9 7.2 14.0 3.6 7.0 3.4 4.0 2 1 2 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Fzo_mitofusin PF04799.13 KXX79144.1 - 3.2 7.3 16.8 1.5 8.4 0.2 3.9 1 1 2 4 4 4 0 fzo-like conserved region HMMR_N PF15905.5 KXX79144.1 - 4.7 6.6 29.0 0.082 12.4 6.0 3.3 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal ORF6C PF10552.9 KXX79144.1 - 4.8 7.3 12.1 6.5 6.9 1.1 4.3 3 2 2 5 5 5 0 ORF6C domain DASH_Spc19 PF08287.11 KXX79144.1 - 5.6 6.8 31.3 3.2 7.6 9.1 4.9 1 1 3 4 4 4 0 Spc19 Laminin_II PF06009.12 KXX79144.1 - 6.9 6.7 25.7 1.6 8.8 5.0 4.5 2 1 2 4 4 4 0 Laminin Domain II ABC_tran_CTD PF16326.5 KXX79144.1 - 9.1 6.6 15.8 6.9 7.0 3.6 5.0 2 2 4 6 6 6 0 ABC transporter C-terminal domain LXG PF04740.12 KXX79144.1 - 9.2 5.9 11.8 2.7 7.7 5.5 2.7 2 1 0 2 2 2 0 LXG domain of WXG superfamily HalX PF08663.10 KXX79144.1 - 10 6.6 20.2 1.5 9.2 0.1 5.1 4 2 1 5 5 5 0 HalX domain RabGAP-TBC PF00566.18 KXX79146.1 - 1.5e-30 106.5 0.0 2.1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KXX79146.1 - 5.7e-07 28.2 0.9 8.7e-07 27.6 0.4 1.4 1 1 0 1 1 1 1 SBE2, cell-wall formation Upf2 PF04050.14 KXX79146.1 - 0.65 10.7 2.8 0.78 10.5 0.4 2.2 2 0 0 2 2 2 0 Up-frameshift suppressor 2 Herpes_UL25 PF01499.16 KXX79146.1 - 0.95 7.9 2.6 0.99 7.8 0.4 1.9 2 0 0 2 2 2 0 Herpesvirus UL25 family DUF604 PF04646.12 KXX79147.1 - 2.7e-12 46.7 0.0 4.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KXX79147.1 - 0.0023 17.4 0.0 0.0065 15.9 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Fungal_trans PF04082.18 KXX79148.1 - 3.7e-09 36.0 0.0 5.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX79148.1 - 6.7e-06 26.1 8.9 1.2e-05 25.3 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_24 PF13578.6 KXX79149.1 - 6.3e-12 46.5 0.0 1.1e-11 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KXX79149.1 - 2.8e-08 33.2 0.0 4.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase NatB_MDM20 PF09797.9 KXX79150.1 - 3.6e-72 243.4 0.0 6.8e-72 242.5 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Ilm1 PF10311.9 KXX79151.1 - 1.2e-65 220.2 0.2 1.4e-65 220.0 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 G-patch PF01585.23 KXX79152.1 - 1.1e-07 31.6 0.1 1.9e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 G-patch domain Ras PF00071.22 KXX79153.1 - 5.5e-65 217.9 0.0 7.2e-65 217.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX79153.1 - 7.5e-34 116.5 0.0 1.4e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX79153.1 - 4.5e-13 49.0 0.0 5.5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXX79153.1 - 9.1e-06 25.3 0.0 2.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXX79153.1 - 0.00027 20.4 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXX79153.1 - 0.0013 18.6 0.2 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXX79153.1 - 0.0028 17.7 0.0 0.0062 16.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX79153.1 - 0.016 14.7 0.0 0.08 12.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KXX79153.1 - 0.029 13.8 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KXX79153.1 - 0.13 12.5 0.1 0.49 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain Sec63 PF02889.16 KXX79154.1 - 4.3e-133 442.3 0.0 2.6e-80 269.3 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXX79154.1 - 3.9e-50 170.1 0.0 1.4e-26 93.4 0.3 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KXX79154.1 - 3.7e-22 79.1 0.0 2.4e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXX79154.1 - 4.9e-16 59.1 0.2 9.5e-07 29.2 0.0 4.8 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXX79154.1 - 4.4e-07 29.8 0.2 0.02 14.6 0.3 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KXX79154.1 - 2.4e-06 27.9 0.8 0.23 11.8 0.2 3.7 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXX79154.1 - 1.8e-05 25.1 0.3 0.0026 18.1 0.5 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXX79154.1 - 0.00057 20.3 0.2 2.6 8.5 0.0 4.5 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 KXX79154.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain TniB PF05621.11 KXX79154.1 - 0.093 12.1 0.2 19 4.6 0.0 3.8 4 0 0 4 4 4 0 Bacterial TniB protein FA_hydroxylase PF04116.13 KXX79155.1 - 9.7e-27 93.9 15.1 9.7e-27 93.9 15.1 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily NCA2 PF08637.10 KXX79156.1 - 3.7e-109 364.4 0.1 6.3e-109 363.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 bZIP_1 PF00170.21 KXX79157.1 - 6.9e-09 35.7 7.3 2.4e-08 33.9 7.3 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXX79157.1 - 0.42 10.7 9.1 19 5.4 9.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Pterin_4a PF01329.19 KXX79158.1 - 9.9e-23 80.1 0.2 1.3e-22 79.8 0.2 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase SUIM_assoc PF16619.5 KXX79158.1 - 0.013 15.5 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DASH_Dad4 PF08650.10 KXX79159.1 - 2.7e-27 94.5 6.8 2.8e-27 94.5 6.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 HOK_GEF PF01848.16 KXX79159.1 - 0.03 13.7 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Hok/gef family Biotin_carb_C PF02785.19 KXX79159.1 - 0.04 14.0 0.1 0.044 13.9 0.1 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain GM_CSF PF01109.17 KXX79159.1 - 0.043 14.0 0.4 0.048 13.8 0.4 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Actin PF00022.19 KXX79160.1 - 3.1e-55 187.4 0.0 1.7e-32 112.6 0.0 2.3 2 1 0 2 2 2 2 Actin adh_short PF00106.25 KXX79161.1 - 2.1e-40 138.3 0.0 2.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX79161.1 - 9.7e-34 116.9 0.0 1.4e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX79161.1 - 9.6e-14 51.7 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1182 PF06681.13 KXX79161.1 - 0.096 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) DUF1776 PF08643.10 KXX79161.1 - 0.18 11.2 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2717 PF10911.8 KXX79161.1 - 0.19 11.5 0.0 0.65 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) FSH1 PF03959.13 KXX79162.1 - 2.8e-32 112.1 0.0 3.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXX79162.1 - 1.7e-05 25.5 0.9 2.5e-05 25.0 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX79162.1 - 2e-05 24.5 0.0 0.00036 20.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PE-PPE PF08237.11 KXX79162.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_3 PF07859.13 KXX79162.1 - 0.13 12.1 0.3 0.33 10.8 0.3 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KXX79163.1 - 1.2e-34 119.8 46.4 1.2e-34 119.8 46.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX79163.1 - 2.8e-09 36.3 14.1 2.8e-09 36.3 14.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Tri3 PF07428.11 KXX79164.1 - 3.3e-07 29.6 0.0 0.012 14.6 0.0 2.7 2 1 1 3 3 3 2 15-O-acetyltransferase Tri3 PapA_C PF16911.5 KXX79164.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus COMP PF11598.8 KXX79165.1 - 0.21 12.1 0.1 0.38 11.3 0.1 1.3 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Ion_trans PF00520.31 KXX79166.1 - 7.7e-09 35.1 23.3 1.3e-08 34.4 23.3 1.3 1 0 0 1 1 1 1 Ion transport protein CPSase_L_D2 PF02786.17 KXX79167.1 - 7.8e-107 355.5 0.2 4.4e-84 281.2 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KXX79167.1 - 9.1e-46 154.8 0.0 2e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KXX79167.1 - 2.7e-45 154.5 0.0 5.1e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KXX79167.1 - 3.1e-44 150.6 0.0 7.8e-44 149.3 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KXX79167.1 - 3.6e-39 133.9 0.0 1.2e-38 132.2 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KXX79167.1 - 9.2e-21 74.6 0.0 2.3e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KXX79167.1 - 1.8e-20 72.9 0.0 8.6e-20 70.7 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KXX79167.1 - 3.5e-15 56.1 0.7 6e-07 29.2 0.1 2.7 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXX79167.1 - 8.3e-14 51.5 0.1 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 KXX79167.1 - 3.4e-05 23.7 0.4 0.0045 16.8 0.4 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 KXX79167.1 - 9.6e-05 22.2 0.1 0.91 9.2 0.0 3.1 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 KXX79167.1 - 0.0018 18.1 0.0 0.21 11.4 0.0 3.7 4 0 0 4 4 4 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 KXX79167.1 - 0.0031 17.6 0.5 1.4 9.0 0.1 2.9 2 0 0 2 2 2 2 ATP-grasp domain Transferase PF02458.15 KXX79168.1 - 1.6e-16 60.0 0.0 3.5e-16 58.9 0.0 1.4 2 0 0 2 2 2 1 Transferase family PapA_C PF16911.5 KXX79169.1 - 0.00057 19.9 0.1 0.0033 17.5 0.0 2.3 1 1 1 2 2 2 2 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus FAD_binding_4 PF01565.23 KXX79170.1 - 2.3e-28 98.7 1.7 3.5e-28 98.1 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX79170.1 - 1.1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KXX79171.1 - 1.8e-17 63.4 0.3 4.5e-16 58.9 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX79171.1 - 1.5e-07 31.2 0.0 6.1e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX79171.1 - 8.4e-07 29.1 0.7 2.3e-06 27.6 0.0 1.9 2 1 1 3 3 3 1 KR domain Epimerase PF01370.21 KXX79171.1 - 2.3e-06 27.2 0.0 4.7e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX79171.1 - 0.00028 20.4 4.2 0.51 9.7 0.0 2.9 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase E1-N PF14463.6 KXX79171.1 - 0.0039 17.0 0.1 0.011 15.6 0.0 1.8 1 1 1 2 2 2 1 E1 N-terminal domain Ldh_1_N PF00056.23 KXX79171.1 - 0.13 12.3 0.0 22 5.1 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 KXX79171.1 - 0.14 11.8 0.1 3.8 7.1 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Peptidase_C12 PF01088.21 KXX79174.1 - 1.1e-52 178.8 0.0 1.4e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUV3_C PF12513.8 KXX79175.1 - 6.7e-18 64.3 2.5 1.3e-17 63.4 1.0 2.3 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KXX79175.1 - 2.5e-11 43.3 0.1 5.5e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 KXX79175.1 - 4.8e-09 36.6 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.18 KXX79175.1 - 0.035 14.0 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase Synaptobrevin PF00957.21 KXX79176.1 - 1.3e-30 105.0 0.0 1.9e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXX79176.1 - 9.4e-27 92.9 0.1 1.6e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Cation_efflux PF01545.21 KXX79176.1 - 0.019 14.7 0.9 0.062 13.0 0.1 2.0 2 0 0 2 2 2 0 Cation efflux family TAP42 PF04177.12 KXX79178.1 - 1.1e-111 373.0 0.1 1.2e-111 372.8 0.1 1.0 1 0 0 1 1 1 1 TAP42-like family KBP_C PF12309.8 KXX79178.1 - 0.013 15.0 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal PNP_phzG_C PF10590.9 KXX79179.1 - 9.5e-22 76.8 1.8 1.5e-20 72.9 2.8 2.3 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KXX79179.1 - 4.1e-12 46.1 0.0 2.4e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KXX79179.1 - 0.12 12.9 0.0 0.3 11.7 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF3833 PF12915.7 KXX79179.1 - 0.2 11.2 0.5 12 5.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3833) Ribonuclease_3 PF00636.26 KXX79180.1 - 1.9e-38 131.3 0.0 1.3e-17 64.4 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KXX79180.1 - 3.4e-22 78.4 0.0 4.7e-21 74.8 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KXX79180.1 - 6.6e-21 74.8 0.0 7.4e-09 35.8 0.0 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.31 KXX79180.1 - 1.1e-13 51.4 0.1 2.8e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX79180.1 - 2.6e-12 47.1 0.0 5.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXX79180.1 - 1.8e-10 40.8 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXX79180.1 - 0.049 13.9 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 KXX79180.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF4632 PF15451.6 KXX79181.1 - 0.12 12.5 1.5 0.76 9.9 1.5 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF4360 PF14273.6 KXX79182.1 - 3.9e-08 33.4 0.0 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ketoacyl-synt PF00109.26 KXX79183.1 - 1.3e-71 241.2 0.1 5.7e-71 239.1 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 KXX79183.1 - 1.5e-35 120.9 0.0 4.4e-35 119.4 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 KXX79183.1 - 2.4e-31 108.2 0.0 7e-31 106.7 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXX79183.1 - 6.2e-30 104.2 0.0 1.2e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KXX79183.1 - 1.2e-19 71.0 0.0 3.2e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 KXX79183.1 - 5.2e-16 59.1 6.5 1.3e-12 48.0 0.2 3.4 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 KXX79183.1 - 2.8e-13 50.4 0.0 1.1e-12 48.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXX79183.1 - 1.1e-09 38.5 0.5 3.3e-09 37.0 0.5 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KXX79183.1 - 1.3e-09 37.9 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KXX79183.1 - 3.5e-08 33.5 0.0 9.8e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 KXX79183.1 - 4.6e-08 32.6 0.0 1.2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_25 PF13649.6 KXX79183.1 - 1.7e-07 31.8 0.0 5.3e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX79183.1 - 9.3e-07 29.4 0.0 6.3e-06 26.8 0.0 2.5 3 0 0 3 3 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXX79183.1 - 5.7e-06 25.9 0.2 0.00017 21.0 0.0 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KXX79183.1 - 0.00011 22.7 0.0 0.00028 21.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KXX79183.1 - 0.00077 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 KXX79183.1 - 0.0027 17.6 0.0 0.0083 16.1 0.0 1.8 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KXX79183.1 - 0.013 14.7 0.0 4.1 6.4 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Arabino_trans_N PF17689.1 KXX79183.1 - 0.04 14.1 1.0 0.1 12.8 1.0 1.6 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain Polysacc_synt_2 PF02719.15 KXX79183.1 - 0.078 12.1 0.0 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 KXX79183.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family ATP_synt_H PF05493.13 KXX79184.1 - 1.5e-24 86.2 1.6 1.7e-24 86.0 1.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H YfhO PF09586.10 KXX79184.1 - 0.048 11.9 0.2 0.048 11.9 0.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.6 KXX79184.1 - 0.06 13.0 1.1 0.065 12.9 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NAD_binding_2 PF03446.15 KXX79185.1 - 4.5e-28 98.4 0.0 7.4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXX79185.1 - 6.5e-08 33.1 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 KXX79185.1 - 2.3e-07 31.1 0.1 3.9e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KXX79185.1 - 8.4e-07 29.1 0.0 2e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HMGL-like PF00682.19 KXX79185.1 - 0.006 16.2 0.2 0.0096 15.5 0.2 1.2 1 0 0 1 1 1 1 HMGL-like Sacchrp_dh_NADP PF03435.18 KXX79185.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KXX79185.1 - 0.048 13.5 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 KXX79185.1 - 0.062 12.9 0.1 0.16 11.5 0.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KXX79185.1 - 0.11 12.8 0.5 0.32 11.2 0.5 1.8 1 1 0 1 1 1 0 TrkA-N domain Ank_2 PF12796.7 KXX79186.1 - 7.6e-29 100.1 0.0 1.8e-15 57.3 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX79186.1 - 9.6e-24 83.5 0.3 9.5e-09 35.6 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX79186.1 - 4.4e-22 75.8 0.3 0.0053 17.1 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KXX79186.1 - 1.7e-18 66.2 0.0 0.00017 21.8 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXX79186.1 - 3.6e-11 43.1 0.3 1.1e-05 25.6 0.0 4.6 1 1 4 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 KXX79186.1 - 6.2e-11 42.5 0.1 3.7e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXX79186.1 - 0.0014 18.9 0.0 0.0052 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX79186.1 - 0.0015 18.9 0.5 0.0079 16.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KXX79186.1 - 0.012 14.8 0.0 1.4 8.1 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain DUF3767 PF12597.8 KXX79186.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Metallophos PF00149.28 KXX79187.1 - 1.1e-31 110.9 0.0 4.9e-23 82.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXX79187.1 - 0.0012 19.3 0.1 0.0041 17.5 0.1 1.9 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribonucleas_3_3 PF14622.6 KXX79188.1 - 4.6e-08 33.3 0.0 0.0009 19.4 0.1 2.3 1 1 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXX79188.1 - 1.2e-06 29.1 0.0 5.9e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KXX79188.1 - 0.00047 20.8 0.0 0.0009 19.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Septin PF00735.18 KXX79190.1 - 4.9e-119 396.8 0.2 4.9e-119 396.8 0.2 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXX79190.1 - 2.5e-08 34.0 1.0 3.9e-08 33.4 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXX79190.1 - 2e-05 24.2 1.7 0.00039 20.0 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXX79190.1 - 8.6e-05 22.5 2.7 0.003 17.5 0.7 3.2 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KXX79190.1 - 0.00011 22.7 0.6 0.029 14.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 KXX79190.1 - 0.0017 17.7 1.4 0.0033 16.8 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KXX79190.1 - 0.0022 18.2 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KXX79190.1 - 0.0027 18.1 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KXX79190.1 - 0.013 15.1 0.7 0.058 13.0 0.0 2.3 3 0 0 3 3 3 0 Ras family AAA_22 PF13401.6 KXX79190.1 - 0.016 15.5 0.7 0.045 14.0 0.1 2.2 2 2 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXX79190.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KXX79190.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXX79190.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KXX79190.1 - 0.11 12.5 7.6 1.1 9.3 0.0 3.7 4 1 0 4 4 3 0 Dynamin family AAA_7 PF12775.7 KXX79190.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KXX79190.1 - 0.17 12.3 0.4 0.78 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KXX79190.1 - 0.27 11.0 3.4 5.1 6.8 0.1 3.0 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 KXX79190.1 - 0.68 9.5 6.1 1 8.8 6.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 KXX79190.1 - 2.1 8.4 4.3 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 KXX79190.1 - 5.6 5.9 8.6 8.5 5.4 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PLA2_B PF01735.18 KXX79191.1 - 9.2e-26 90.3 0.0 2.1e-25 89.1 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain La PF05383.17 KXX79192.1 - 7.9e-21 73.9 0.0 1.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXX79192.1 - 1.4e-06 28.0 0.4 3.9e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.25 KXX79193.1 - 2.5e-15 55.9 0.0 5.4e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain DUF2089 PF09862.9 KXX79193.1 - 0.0063 16.5 0.3 0.83 9.7 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) S4_2 PF13275.6 KXX79193.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 S4 domain M16C_assoc PF08367.11 KXX79193.1 - 0.24 10.5 0.0 0.24 10.5 0.0 2.0 3 0 0 3 3 3 0 Peptidase M16C associated MscS_TM PF12794.7 KXX79193.1 - 0.82 8.5 4.9 0.93 8.3 2.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Sigma70_ner PF04546.13 KXX79193.1 - 5.8 6.7 10.8 0.37 10.6 5.0 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Cyclin_N PF00134.23 KXX79194.1 - 0.0014 18.4 0.1 0.0051 16.5 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Zn_clus PF00172.18 KXX79196.1 - 0.026 14.7 2.1 0.05 13.7 2.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_meth_N PF18284.1 KXX79196.1 - 0.15 12.0 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 DNA methylase N-terminal domain Ku PF02735.16 KXX79197.1 - 1.6e-46 158.6 0.0 3.3e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KXX79197.1 - 1.8e-35 122.7 0.0 3.3e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KXX79197.1 - 1.1e-29 103.0 0.5 1.1e-29 103.0 0.5 2.4 2 1 1 3 3 3 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KXX79197.1 - 1.9e-08 33.8 1.3 1.9e-08 33.8 1.3 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 KXX79197.1 - 0.011 15.5 0.3 0.011 15.5 0.3 2.0 2 0 0 2 2 2 0 HeH/LEM domain VWA_2 PF13519.6 KXX79197.1 - 0.12 13.0 0.0 0.65 10.7 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain Ferrochelatase PF00762.19 KXX79198.1 - 1.2e-99 333.5 0.0 1.3e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Zn_clus PF00172.18 KXX79199.1 - 2.2e-08 34.1 8.2 4.4e-08 33.1 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX79199.1 - 0.00027 19.9 0.6 0.00045 19.1 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KXX79200.1 - 6.9e-37 127.1 6.9 1.2e-36 126.2 6.9 1.4 1 0 0 1 1 1 1 RTA1 like protein SepZ PF06066.11 KXX79200.1 - 0.12 12.6 2.4 0.22 11.7 2.4 1.4 1 0 0 1 1 1 0 SepZ MFS_1 PF07690.16 KXX79201.1 - 3.4e-26 92.0 38.3 1.3e-20 73.6 15.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX79201.1 - 5.6e-08 32.1 0.9 5.6e-08 32.1 0.9 2.4 3 1 0 3 3 3 1 Sugar (and other) transporter DUF1751 PF08551.10 KXX79201.1 - 0.0049 17.4 3.3 0.0082 16.7 0.3 2.8 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) DUF5326 PF17260.2 KXX79201.1 - 0.19 11.9 0.1 0.19 11.9 0.1 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5326) HIT PF01230.23 KXX79202.1 - 8e-20 71.4 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXX79202.1 - 0.22 12.0 0.0 7.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Fungal_trans PF04082.18 KXX79203.1 - 3.5e-43 147.5 0.0 7.6e-43 146.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX79203.1 - 9.7e-09 35.2 6.6 2e-08 34.2 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1844 PF08899.11 KXX79203.1 - 0.093 13.0 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) BAR_2 PF10455.9 KXX79204.1 - 2e-58 197.8 0.2 3e-58 197.3 0.2 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KXX79204.1 - 2.7e-20 73.1 3.7 2.6e-19 69.8 3.7 2.1 1 1 0 1 1 1 1 BAR domain LSM PF01423.22 KXX79204.1 - 9.1e-15 54.1 0.0 1.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 LSM domain PPR_2 PF13041.6 KXX79204.1 - 1.7e-13 50.5 0.0 0.0016 18.6 0.0 5.0 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 KXX79204.1 - 4.6e-10 39.0 0.9 0.19 12.0 0.0 4.8 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 KXX79204.1 - 2.1e-07 30.6 0.0 0.00025 20.5 0.0 3.3 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KXX79204.1 - 6.4e-07 29.3 0.0 0.0055 16.7 0.0 3.5 3 0 0 3 3 3 2 Pentatricopeptide repeat domain TPR_14 PF13428.6 KXX79204.1 - 0.00082 20.0 0.2 45 5.2 0.0 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.7 KXX79204.1 - 0.018 14.7 0.0 0.85 9.4 0.0 3.5 4 0 0 4 4 4 0 PPR repeat BAR_3 PF16746.5 KXX79204.1 - 0.024 14.3 0.2 0.06 13.0 0.1 1.7 2 0 0 2 2 2 0 BAR domain of APPL family NAT PF04768.13 KXX79205.1 - 1.1e-48 165.1 0.0 7.5e-48 162.4 0.0 2.0 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Trp_halogenase PF04820.14 KXX79206.1 - 3.1e-12 46.1 0.3 2.6e-11 43.0 0.2 2.2 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KXX79206.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.6 1 1 0 1 1 1 0 FAD binding domain Amidohydro_2 PF04909.14 KXX79207.1 - 2.2e-33 116.3 0.3 2.8e-33 115.9 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase SGL PF08450.12 KXX79208.1 - 0.00092 18.9 0.0 0.0044 16.6 0.0 2.0 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NAD_binding_10 PF13460.6 KXX79209.1 - 5.8e-07 29.6 0.0 8.1e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXX79209.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXX79209.1 - 0.076 12.5 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXX79209.1 - 0.12 11.5 0.0 6.9 5.8 0.0 2.4 2 1 1 3 3 3 0 Male sterility protein p450 PF00067.22 KXX79210.1 - 1.3e-62 212.1 0.0 1.6e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MLTR_LBD PF17765.1 KXX79210.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain FAD_binding_4 PF01565.23 KXX79211.1 - 1.5e-21 76.6 3.3 2.5e-21 75.9 3.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX79211.1 - 0.054 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like COA2 PF17051.5 KXX79215.1 - 2.6e-05 24.2 0.9 3.1e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 Cytochrome C oxidase assembly factor 2 ketoacyl-synt PF00109.26 KXX79217.1 - 3.9e-75 252.7 0.0 1.2e-74 251.1 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXX79217.1 - 1.8e-36 124.7 0.7 3.7e-36 123.7 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KXX79217.1 - 1.1e-28 100.7 0.0 1.1e-24 87.5 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.6 KXX79217.1 - 1.1e-26 93.8 0.1 2.2e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXX79217.1 - 1.6e-19 70.0 6.5 1.9e-11 44.1 1.6 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site HTH_51 PF18558.1 KXX79217.1 - 1.2e-18 66.7 0.0 3.6e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain SAT PF16073.5 KXX79217.1 - 2.2e-13 50.5 2.8 1.4e-09 38.1 0.1 4.0 4 1 0 4 4 4 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 KXX79217.1 - 2.4e-12 47.5 0.0 7.7e-12 45.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 KXX79217.1 - 5.2e-12 46.1 0.1 2.1e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 KXX79217.1 - 1e-09 39.0 0.0 5.5e-09 36.6 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX79217.1 - 3.5e-07 30.2 0.0 2.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.21 KXX79217.1 - 4.7e-07 29.5 0.0 0.00013 21.6 0.0 2.7 3 0 0 3 3 2 1 Prolyl oligopeptidase family Methyltransf_11 PF08241.12 KXX79217.1 - 4.8e-07 30.3 0.0 1.4e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXX79217.1 - 3.9e-06 26.4 0.1 9.5e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 KXX79217.1 - 1e-05 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.7 KXX79217.1 - 1.2e-05 26.0 8.3 0.001 19.8 3.9 3.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KXX79217.1 - 1.7e-05 25.3 0.0 0.00017 22.0 0.0 2.6 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 KXX79217.1 - 0.00025 20.4 0.1 0.00095 18.5 0.0 2.0 2 0 0 2 2 1 1 Serine aminopeptidase, S33 Ubie_methyltran PF01209.18 KXX79217.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 KXX79217.1 - 0.022 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent ACP_syn_III PF08545.10 KXX79217.1 - 0.026 14.4 0.2 0.11 12.4 0.2 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III COesterase PF00135.28 KXX79217.1 - 0.038 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DLH PF01738.18 KXX79217.1 - 0.084 12.4 0.0 1.3 8.5 0.0 2.6 3 0 0 3 3 2 0 Dienelactone hydrolase family Methyltransf_28 PF02636.17 KXX79217.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.16 KXX79219.1 - 1.7e-10 40.4 4.1 2e-10 40.1 4.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.13 KXX79219.1 - 0.12 12.7 4.1 0.3 11.4 4.1 1.7 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Fungal_trans PF04082.18 KXX79220.1 - 4.3e-09 35.8 0.0 8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX79220.1 - 1e-05 25.6 7.5 1.8e-05 24.7 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rib_5-P_isom_A PF06026.14 KXX79221.1 - 3.7e-48 163.4 0.0 5e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KXX79221.1 - 0.12 12.3 0.0 21 5.0 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain AAA PF00004.29 KXX79222.1 - 9.3e-16 58.5 0.0 2e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXX79222.1 - 0.0041 17.1 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXX79222.1 - 0.035 14.3 0.1 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX79222.1 - 0.058 13.8 0.2 0.21 12.0 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXX79222.1 - 0.069 13.7 0.0 0.3 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXX79222.1 - 0.075 13.3 0.3 0.075 13.3 0.3 3.0 3 1 1 4 4 4 0 AAA domain SOBP PF15279.6 KXX79222.1 - 4.4 7.8 16.4 11 6.5 16.4 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein PKD_channel PF08016.12 KXX79223.1 - 7.3e-06 24.9 15.4 0.00018 20.3 15.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KXX79223.1 - 8.4e-05 21.9 21.8 0.001 18.4 21.8 2.1 1 1 0 1 1 1 1 Ion transport protein UPF0542 PF15086.6 KXX79223.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Sigma_reg_N PF13800.6 KXX79223.1 - 1.5 9.1 3.4 11 6.4 0.1 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Ac76 PF05814.11 KXX79223.1 - 2.1 8.4 6.5 0.91 9.6 0.4 2.9 2 0 0 2 2 2 0 Orf76 (Ac76) XAP5 PF04921.14 KXX79224.1 - 1.3e-93 313.4 0.0 3.8e-93 311.9 0.0 1.7 1 1 1 2 2 2 2 XAP5, circadian clock regulator DUF4604 PF15377.6 KXX79224.1 - 0.013 16.0 4.1 0.013 16.0 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Herpes_US12 PF05363.12 KXX79224.1 - 0.13 13.0 4.0 0.11 13.2 0.8 2.5 2 0 0 2 2 2 0 Herpesvirus US12 family Methyltransf_10 PF05971.12 KXX79225.1 - 7e-66 222.6 0.0 9e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KXX79225.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXX79225.1 - 0.0027 18.4 0.0 0.043 14.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX79225.1 - 0.024 14.4 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 KXX79225.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXX79225.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KXX79225.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 KXX79225.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase SPESP1 PF15754.5 KXX79226.1 - 0.026 13.7 3.6 0.048 12.8 3.6 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Promethin PF16015.5 KXX79227.1 - 0.33 10.9 7.2 1.2 9.1 1.0 2.2 2 0 0 2 2 2 0 Promethin Asp PF00026.23 KXX79229.1 - 9.5e-40 136.9 0.1 1.7e-39 136.1 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KXX79229.1 - 3.6e-07 30.7 0.0 1 10.0 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.6 KXX79229.1 - 3.9e-05 23.5 0.0 0.00079 19.2 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KXX79229.1 - 0.0039 17.7 0.0 11 6.6 0.0 3.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 KXX79229.1 - 0.22 11.8 0.7 16 5.6 0.7 3.2 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal SH3_1 PF00018.28 KXX79230.1 - 0.00017 21.1 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX79230.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 KXX79230.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Ank_2 PF12796.7 KXX79231.1 - 8.8e-85 279.4 13.2 6.8e-16 58.6 0.1 7.1 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX79231.1 - 4.5e-56 186.5 13.1 3.4e-10 40.3 0.0 10.4 3 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX79231.1 - 1.9e-52 169.1 11.6 2.6e-05 24.3 0.0 14.1 14 0 0 14 14 14 11 Ankyrin repeat Ank PF00023.30 KXX79231.1 - 1.1e-50 168.0 27.9 1.2e-06 28.7 0.0 13.6 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 KXX79231.1 - 2.1e-47 158.5 15.8 1.9e-09 37.6 0.0 11.4 5 3 7 12 12 12 9 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KXX79231.1 - 5.4e-05 22.7 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins MRP-L28 PF09812.9 KXX79232.1 - 0.068 13.3 1.3 2.8 8.1 0.6 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L28 IFT57 PF10498.9 KXX79232.1 - 0.069 12.1 2.6 0.12 11.3 2.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KXX79232.1 - 0.12 11.2 6.0 0.22 10.4 6.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CK2S PF15011.6 KXX79232.1 - 0.14 12.0 3.1 0.24 11.3 2.1 1.8 2 0 0 2 2 2 0 Casein Kinase 2 substrate MetOD2 PF18548.1 KXX79232.1 - 0.17 12.0 2.8 0.22 11.6 0.7 2.2 2 0 0 2 2 2 0 Metanogen output domain 2 Phlebovirus_NSM PF07246.11 KXX79232.1 - 0.28 10.5 4.3 0.47 9.8 4.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Sipho_Gp157 PF05565.11 KXX79232.1 - 0.43 10.6 4.9 0.85 9.6 4.9 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 MFS_1 PF07690.16 KXX79233.1 - 3.1e-39 134.9 32.4 4e-39 134.5 32.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CDH-cyt PF16010.5 KXX79234.1 - 9.8e-08 31.9 4.9 7.3e-06 25.8 0.0 2.9 3 0 0 3 3 3 2 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KXX79234.1 - 1.1e-06 28.8 10.2 2e-06 27.9 10.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KXX79234.1 - 1.7 8.5 7.9 0.11 12.3 2.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) MFS_1 PF07690.16 KXX79236.1 - 6.5e-14 51.6 8.7 8e-11 41.4 1.7 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX79236.1 - 0.018 13.9 1.7 0.024 13.5 0.2 1.9 2 0 0 2 2 2 0 Sugar (and other) transporter Fuseless PF15993.5 KXX79236.1 - 0.054 12.7 1.8 0.1 11.8 1.8 1.3 1 0 0 1 1 1 0 Fuseless UDPGT PF00201.18 KXX79238.1 - 4.6e-14 52.1 0.0 6.6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Rep_fac_C PF08542.11 KXX79239.1 - 4.9e-18 65.3 0.2 1.8e-17 63.5 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXX79239.1 - 1.2e-16 61.3 1.1 8.5e-16 58.6 0.1 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXX79239.1 - 5.4e-13 49.0 0.0 1.6e-12 47.5 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KXX79239.1 - 3.6e-08 33.5 0.0 9.1e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KXX79239.1 - 3.3e-07 30.2 0.0 6.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KXX79239.1 - 3.7e-07 30.4 0.1 1.2e-06 28.8 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_22 PF13401.6 KXX79239.1 - 9.8e-07 29.1 0.3 6.3e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.6 KXX79239.1 - 2.8e-06 27.3 0.1 8.7e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX79239.1 - 7.3e-06 26.5 0.0 3.1e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KXX79239.1 - 3.2e-05 23.7 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KXX79239.1 - 4.4e-05 23.3 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 KXX79239.1 - 5.6e-05 23.1 0.2 0.00015 21.8 0.1 1.7 1 1 1 2 2 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXX79239.1 - 8.2e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KXX79239.1 - 0.00034 21.0 0.1 0.0012 19.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXX79239.1 - 0.00037 20.3 0.0 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KXX79239.1 - 0.00042 20.2 0.1 0.0016 18.3 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXX79239.1 - 0.00043 20.3 0.0 0.00083 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KXX79239.1 - 0.00069 19.1 0.4 0.95 8.9 0.0 2.9 2 1 1 3 3 3 2 PhoH-like protein ResIII PF04851.15 KXX79239.1 - 0.00089 19.3 0.0 0.061 13.3 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 KXX79239.1 - 0.0032 16.9 0.1 0.052 13.0 0.0 2.6 3 0 0 3 3 3 1 Bacterial TniB protein AAA_28 PF13521.6 KXX79239.1 - 0.0038 17.5 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KXX79239.1 - 0.0093 15.7 0.1 0.052 13.3 0.2 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 KXX79239.1 - 0.011 16.2 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TAFII28 PF04719.14 KXX79239.1 - 0.017 15.2 0.0 0.063 13.4 0.0 1.9 2 0 0 2 2 2 0 hTAFII28-like protein conserved region AAA_7 PF12775.7 KXX79239.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KXX79239.1 - 0.022 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KXX79239.1 - 0.024 14.0 0.1 0.17 11.2 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXX79239.1 - 0.029 13.9 0.1 0.14 11.8 0.0 2.1 2 1 1 3 3 3 0 AAA domain ATPase_2 PF01637.18 KXX79239.1 - 0.033 14.1 0.0 0.098 12.6 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXX79239.1 - 0.099 12.4 0.1 0.55 9.9 0.1 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KXX79239.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 RNA helicase MiaE PF06175.11 KXX79239.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Cnd1 PF12717.7 KXX79239.1 - 0.12 12.5 1.3 3.3 7.7 0.2 2.4 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 ABC_tran PF00005.27 KXX79239.1 - 0.15 12.5 0.0 0.35 11.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DUF1586 PF07625.11 KXX79240.1 - 1 9.4 5.5 1.1 9.4 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1586) TauD PF02668.16 KXX79242.1 - 2.3e-44 152.2 0.1 3e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UL16 PF17622.2 KXX79242.1 - 0.032 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral unique long protein 16 SR-25 PF10500.9 KXX79243.1 - 7.9 6.0 15.2 2.8 7.5 4.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Amidohydro_1 PF01979.20 KXX79244.1 - 1.1e-22 80.9 0.1 2.6e-22 79.6 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXX79244.1 - 2.4e-08 33.9 1.3 2.4e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family COX16 PF14138.6 KXX79245.1 - 4.3e-28 97.6 0.3 4.7e-28 97.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 HTH_17 PF12728.7 KXX79245.1 - 0.01 16.0 0.3 0.013 15.7 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sel1 PF08238.12 KXX79247.1 - 9.4e-49 162.8 19.4 7.5e-09 36.0 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_20 PF14561.6 KXX79247.1 - 0.16 12.3 2.6 0.17 12.2 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KXX79248.1 - 4.2e-56 190.2 0.1 2.5e-35 122.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79248.1 - 4.2e-37 127.8 0.0 2.9e-36 125.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX79248.1 - 0.00023 20.6 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXX79248.1 - 0.0086 14.9 0.2 0.46 9.2 0.0 2.5 2 0 0 2 2 2 1 Fungal protein kinase DUF3896 PF13035.6 KXX79248.1 - 0.056 13.6 0.1 0.21 11.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) DUF4140 PF13600.6 KXX79248.1 - 0.087 13.3 0.2 0.27 11.7 0.2 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 KXX79248.1 - 0.28 10.2 5.9 0.51 9.4 5.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2 PF00096.26 KXX79249.1 - 4.6e-09 36.2 10.8 0.00044 20.5 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX79249.1 - 7.4e-06 26.2 9.2 2.1e-05 24.7 1.5 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX79249.1 - 0.00014 22.4 10.1 0.11 13.4 1.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXX79249.1 - 0.011 15.7 0.9 0.011 15.7 0.9 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KXX79249.1 - 0.035 14.5 3.7 0.077 13.4 1.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXX79249.1 - 0.083 13.2 0.4 0.083 13.2 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GDI PF00996.18 KXX79250.1 - 1.7e-24 86.1 0.0 3.6e-24 85.1 0.0 1.4 1 1 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.13 KXX79251.1 - 5.4e-31 107.0 0.0 9.1e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXX79251.1 - 2.1e-08 33.3 0.1 4.8e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ALO PF04030.14 KXX79252.1 - 2.5e-95 319.2 0.3 3.2e-95 318.9 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KXX79252.1 - 1.5e-30 105.7 0.1 2.2e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain BTB PF00651.31 KXX79253.1 - 2.3e-25 89.0 0.9 2.4e-12 47.1 0.2 3.2 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 KXX79253.1 - 7e-07 29.8 0.0 2.6e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXX79253.1 - 9.9e-07 28.9 0.0 0.028 14.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXX79253.1 - 4.7e-06 26.8 0.0 1.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX79253.1 - 8.2e-06 25.8 0.2 0.14 12.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXX79253.1 - 1.7e-05 25.2 0.1 4.4e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ExsD PF16806.5 KXX79253.1 - 0.063 13.2 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Antiactivator protein ExsD MPC PF03650.13 KXX79254.1 - 1.4e-46 157.2 0.4 1.7e-46 156.9 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers L51_S25_CI-B8 PF05047.16 KXX79255.1 - 1e-10 41.4 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 KXX79255.1 - 0.079 13.7 0.0 0.09 13.5 0.0 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain Abhydrolase_1 PF00561.20 KXX79256.1 - 3e-12 46.7 0.0 2e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX79256.1 - 5.2e-09 35.7 0.0 9.3e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXX79256.1 - 2.5e-08 34.8 1.0 2.5e-08 34.8 1.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KXX79256.1 - 0.0063 16.5 0.0 0.65 9.9 0.0 2.8 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal RNase_PH PF01138.21 KXX79257.1 - 2.1e-16 60.6 0.0 1.1e-15 58.4 0.0 2.1 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXX79257.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF4552 PF15089.6 KXX79258.1 - 0.0046 16.1 0.5 0.0061 15.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4552) tRNA-synt_His PF13393.6 KXX79258.1 - 0.0047 16.3 0.4 0.045 13.0 0.3 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase DUF1687 PF07955.11 KXX79259.1 - 1.4e-33 116.1 1.4 1.8e-33 115.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Rotamase_2 PF13145.6 KXX79259.1 - 0.2 12.5 3.8 0.66 10.8 0.7 2.1 1 1 1 2 2 2 0 PPIC-type PPIASE domain BORCS6 PF10157.9 KXX79260.1 - 0.0048 17.1 1.7 0.0053 17.0 0.3 1.8 1 1 1 2 2 2 1 BLOC-1-related complex sub-unit 6 kleA_kleC PF17383.2 KXX79260.1 - 0.0092 16.3 0.2 0.026 14.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized KorC regulated protein A MNR PF15718.5 KXX79260.1 - 0.016 13.4 0.6 0.02 13.1 0.6 1.1 1 0 0 1 1 1 0 Protein moonraker EspB PF05802.11 KXX79260.1 - 0.024 14.7 0.5 2.5 8.0 0.0 2.3 2 1 0 2 2 2 0 Enterobacterial EspB protein AAA_13 PF13166.6 KXX79260.1 - 0.029 13.1 0.4 0.04 12.6 0.4 1.2 1 0 0 1 1 1 0 AAA domain SMP_2 PF10144.9 KXX79260.1 - 0.052 13.2 0.2 0.068 12.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Fzo_mitofusin PF04799.13 KXX79260.1 - 0.061 12.9 0.4 0.11 12.0 0.4 1.4 1 1 0 1 1 1 0 fzo-like conserved region DUF2120 PF09893.9 KXX79260.1 - 0.093 12.8 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Ssu72 PF04722.13 KXX79260.1 - 0.13 11.8 0.3 0.19 11.3 0.3 1.1 1 0 0 1 1 1 0 Ssu72-like protein Rnk_N PF14760.6 KXX79260.1 - 0.98 10.0 9.4 3.3 8.3 5.2 2.8 2 1 0 2 2 2 0 Rnk N-terminus Lipase_GDSL_2 PF13472.6 KXX79261.1 - 9.5e-13 48.9 0.5 1.9e-12 47.9 0.5 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX79261.1 - 3.7e-09 36.8 0.1 9.7e-09 35.5 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXX79261.1 - 0.1 12.7 0.1 0.81 9.8 0.0 2.2 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SCO1-SenC PF02630.14 KXX79262.1 - 4.2e-51 172.4 0.0 5.8e-51 171.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KXX79262.1 - 0.00018 21.4 0.0 0.00043 20.2 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXX79262.1 - 0.002 17.9 0.0 0.064 13.0 0.0 2.2 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KXX79262.1 - 0.038 14.3 0.0 0.079 13.3 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like PHD PF00628.29 KXX79263.1 - 1.6e-11 43.9 7.4 1.6e-11 43.9 7.4 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KXX79263.1 - 0.17 11.5 1.9 0.41 10.3 1.9 1.7 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 KXX79263.1 - 0.2 11.8 4.6 0.46 10.6 4.6 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KXX79263.1 - 1.8 9.0 7.2 4.6 7.7 7.2 1.7 1 0 0 1 1 1 0 Ring finger domain DUF3433 PF11915.8 KXX79264.1 - 5.4e-30 103.7 18.8 1.9e-28 98.7 3.8 4.5 6 0 0 6 6 6 2 Protein of unknown function (DUF3433) Choline_kinase PF01633.20 KXX79265.1 - 3.1e-60 203.4 0.0 8.4e-60 202.0 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KXX79265.1 - 1.9e-20 72.3 0.0 3.9e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KXX79265.1 - 0.0016 18.4 5.9 0.0022 18.0 0.1 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family Peptidase_M24_C PF16188.5 KXX79265.1 - 0.076 13.1 0.2 0.24 11.5 0.2 1.9 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 PepSY_TM_like_2 PF16357.5 KXX79265.1 - 0.18 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative PepSY_TM-like Trypan_PARP PF05887.11 KXX79265.1 - 0.27 11.2 4.6 0.62 10.0 4.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L24e PF01246.20 KXX79268.1 - 4.2e-28 97.4 0.1 4.2e-28 97.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e A_deamin PF02137.18 KXX79269.1 - 3.4e-23 82.6 0.0 3.7e-22 79.2 0.0 2.3 2 1 0 2 2 2 1 Adenosine-deaminase (editase) domain NAC PF01849.18 KXX79270.1 - 7.4e-25 86.7 0.8 2.8e-24 84.9 0.2 2.0 2 0 0 2 2 2 1 NAC domain CBP4 PF07960.11 KXX79271.1 - 7.1e-34 116.5 2.9 8.7e-34 116.2 2.9 1.1 1 0 0 1 1 1 1 CBP4 Seryl_tRNA_N PF02403.22 KXX79271.1 - 0.26 11.5 6.5 0.49 10.7 6.5 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2852 PF11014.8 KXX79271.1 - 4.9 7.3 9.4 1.6 8.9 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF1348 PF07080.11 KXX79274.1 - 2.3e-65 218.4 9.1 2.7e-65 218.1 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KXX79274.1 - 6.4e-08 33.2 0.9 9.5e-08 32.6 0.9 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXX79274.1 - 1.1e-05 25.7 0.1 1.6e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Redoxin PF08534.10 KXX79275.1 - 1.3e-36 125.5 0.0 1.5e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXX79275.1 - 2.6e-09 37.1 0.0 3.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Fumble PF03630.14 KXX79276.1 - 1.4e-144 481.3 0.0 1.7e-144 481.0 0.0 1.1 1 0 0 1 1 1 1 Fumble SelP_N PF04592.14 KXX79276.1 - 0.044 13.2 14.3 0.068 12.6 14.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4780 PF16012.5 KXX79277.1 - 0.078 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) FACT-Spt16_Nlob PF14826.6 KXX79278.1 - 3.5e-57 192.7 0.5 1.1e-56 191.1 0.5 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KXX79278.1 - 1.7e-54 184.1 0.1 1.7e-54 184.1 0.1 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KXX79278.1 - 8.8e-29 100.7 0.0 1.8e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KXX79278.1 - 5.6e-16 58.7 0.4 1.5e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Cyt-b5 PF00173.28 KXX79279.1 - 5e-10 39.4 0.0 5.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2197 PF09963.9 KXX79280.1 - 0.025 14.9 4.3 0.041 14.2 4.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) PolC_DP2 PF03833.13 KXX79280.1 - 0.72 7.6 3.3 0.85 7.4 3.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C2H2 PF00096.26 KXX79281.1 - 2.1e-07 31.0 22.4 0.0023 18.3 7.0 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX79281.1 - 0.011 16.5 5.2 0.011 16.5 5.2 6.6 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXX79281.1 - 0.016 15.2 3.2 0.016 15.2 3.2 3.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX79281.1 - 8.5 6.8 15.5 4.8 7.6 1.1 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXX79282.1 - 0.099 13.5 10.1 1.1 10.3 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Sina PF03145.16 KXX79282.1 - 0.13 12.2 0.8 0.28 11.1 0.8 1.4 1 0 0 1 1 1 0 Seven in absentia protein family PPR_2 PF13041.6 KXX79284.1 - 1.7e-19 69.8 0.0 4e-10 39.7 0.0 4.4 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 KXX79284.1 - 7.4e-13 47.8 4.0 0.0027 17.9 0.0 6.4 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 KXX79284.1 - 9.8e-11 41.2 5.0 8.2e-05 22.2 0.0 6.4 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 KXX79284.1 - 2.6e-09 37.0 0.0 0.0048 16.9 0.0 4.2 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KXX79284.1 - 0.00093 18.6 0.0 0.32 10.3 0.0 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP cwf18 PF08315.12 KXX79285.1 - 8e-47 159.3 7.4 8e-47 159.3 7.4 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor KicB PF03882.14 KXX79285.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 MukF winged-helix domain DUF2057 PF09829.9 KXX79285.1 - 1.9 8.6 7.4 0.21 11.7 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) WD40 PF00400.32 KXX79286.1 - 7.3e-33 112.1 6.6 5.3e-10 39.7 0.1 3.9 4 0 0 4 4 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79286.1 - 8.9e-19 67.6 0.1 9.1e-06 25.9 0.0 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXX79286.1 - 7.3e-16 58.5 1.3 1.7e-13 50.8 1.3 2.2 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KXX79286.1 - 1.4e-11 44.0 0.1 0.0047 15.9 0.0 3.2 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXX79286.1 - 2e-05 23.5 3.8 0.069 11.8 0.1 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.12 KXX79286.1 - 5.1e-05 23.1 2.3 0.85 9.6 0.2 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat HET-S PF17108.5 KXX79286.1 - 0.003 17.2 2.2 0.0086 15.8 2.2 1.8 1 0 0 1 1 1 1 N-terminal small S protein of HET, non-prionic PQQ_2 PF13360.6 KXX79286.1 - 0.012 15.2 3.3 0.036 13.7 3.3 1.8 1 1 0 1 1 1 0 PQQ-like domain AAA_14 PF13173.6 KXX79286.1 - 0.04 14.0 0.0 0.097 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Cytochrom_D1 PF02239.16 KXX79286.1 - 0.059 11.9 0.2 3.1 6.2 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain AAA_16 PF13191.6 KXX79286.1 - 0.063 13.7 0.1 1.5 9.2 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain Proteasome_A_N PF10584.9 KXX79286.1 - 0.096 12.4 0.8 2.3 8.0 0.2 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature FtsK_SpoIIIE PF01580.18 KXX79286.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KXX79286.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HET-s_218-289 PF11558.8 KXX79286.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Het-s 218-289 NYD-SP28_assoc PF14775.6 KXX79286.1 - 0.15 12.1 1.1 46 4.2 0.0 3.5 4 0 0 4 4 3 0 Sperm tail C-terminal domain DUF5570 PF17731.1 KXX79286.1 - 0.22 11.6 3.2 13 5.9 0.1 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5570) Ceramidase_alk PF04734.13 KXX79287.1 - 1.1e-213 710.5 0.0 1.3e-213 710.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KXX79287.1 - 2.6e-59 199.9 0.0 4.3e-59 199.1 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Glyco_hydro_61 PF03443.14 KXX79288.1 - 2.5e-61 207.2 0.1 3e-61 206.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Kelch_3 PF13415.6 KXX79289.1 - 1.1e-19 70.2 13.0 4e-05 23.8 0.1 7.0 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KXX79289.1 - 8.5e-18 64.0 6.7 9.7e-06 25.7 0.0 6.5 5 2 2 7 7 7 3 Kelch motif Kelch_1 PF01344.25 KXX79289.1 - 3.6e-17 61.7 3.2 3.5e-08 32.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KXX79289.1 - 6.3e-16 58.0 10.8 2.9e-05 24.0 0.0 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 KXX79289.1 - 3.2e-15 55.9 16.7 0.00073 19.5 0.1 7.2 7 1 1 8 8 8 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KXX79289.1 - 2.8e-11 42.9 8.7 1.3e-05 25.0 1.3 6.0 5 1 0 5 5 5 2 Kelch motif SPOR PF05036.13 KXX79289.1 - 0.009 16.4 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 Sporulation related domain 2Fe-2S_thioredx PF01257.19 KXX79290.1 - 1.7e-59 199.9 0.1 2.1e-59 199.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HSP9_HSP12 PF04119.12 KXX79290.1 - 0.029 14.8 0.2 0.072 13.5 0.2 1.6 1 0 0 1 1 1 0 Heat shock protein 9/12 CDC50 PF03381.15 KXX79291.1 - 9.4e-83 278.0 0.1 1.1e-82 277.7 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family cNMP_binding PF00027.29 KXX79292.1 - 1.4e-41 140.5 0.0 9.4e-21 73.7 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DNA_pol_viral_N PF00242.17 KXX79293.1 - 0.0033 17.0 6.5 0.0049 16.4 2.1 2.0 1 1 1 2 2 2 2 DNA polymerase (viral) N-terminal domain ALAD PF00490.21 KXX79294.1 - 6.6e-121 403.3 0.0 8.1e-121 403.1 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Acyl_transf_3 PF01757.22 KXX79295.1 - 1.7e-50 172.1 33.9 2.7e-50 171.4 33.9 1.3 1 1 0 1 1 1 1 Acyltransferase family AIM5 PF17050.5 KXX79296.1 - 5.2e-17 62.4 0.3 5.2e-17 62.4 0.3 2.8 2 1 0 2 2 2 1 Altered inheritance of mitochondria 5 ParD PF09386.10 KXX79296.1 - 0.0083 16.5 0.4 0.018 15.4 0.4 1.6 1 0 0 1 1 1 1 Antitoxin ParD DUF883 PF05957.13 KXX79296.1 - 1.3 9.7 10.1 0.27 11.9 5.5 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Ribosomal_L17 PF01196.19 KXX79297.1 - 4.8e-33 113.9 0.1 9.3e-33 113.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 Mn_catalase PF05067.12 KXX79297.1 - 0.031 13.3 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase Mrpl_C PF18502.1 KXX79297.1 - 0.086 13.1 0.3 1.4 9.3 0.1 2.1 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain UTP25 PF06862.12 KXX79298.1 - 4.3e-204 678.7 0.4 5.2e-204 678.4 0.4 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KXX79298.1 - 0.0003 20.6 0.0 0.014 15.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase APH_6_hur PF04655.14 KXX79298.1 - 0.011 15.1 2.6 0.33 10.3 0.1 2.2 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase MitMem_reg PF13012.6 KXX79299.1 - 1.8e-18 67.0 0.3 1.8e-18 67.0 0.3 1.8 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXX79299.1 - 3.3e-16 59.3 0.0 5.9e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RPW8 PF05659.11 KXX79299.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SUZ PF12752.7 KXX79300.1 - 7.7e-15 55.4 2.5 7.7e-15 55.4 2.5 3.3 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 KXX79300.1 - 5.7e-09 35.8 0.3 1.1e-08 34.9 0.3 1.4 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.20 KXX79300.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 S4 PF01479.25 KXX79301.1 - 7.2e-12 44.8 0.1 2e-11 43.4 0.1 1.7 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KXX79301.1 - 3.5e-10 40.6 2.3 5.7e-10 40.0 2.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain THDPS_N_2 PF14805.6 KXX79301.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Y_phosphatase3 PF13350.6 KXX79302.1 - 4.2e-48 164.3 0.0 4.8e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family UME PF08064.13 KXX79302.1 - 0.047 13.6 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 UME (NUC010) domain PTPlike_phytase PF14566.6 KXX79302.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KXX79302.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HeLo PF14479.6 KXX79303.1 - 1.1e-44 152.7 0.0 1.4e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.8 KXX79303.1 - 8.9e-27 92.9 1.6 1.4e-26 92.3 1.6 1.3 1 0 0 1 1 1 1 Het-s 218-289 HET-S PF17108.5 KXX79303.1 - 4.9e-05 23.0 0.1 0.091 12.5 0.1 2.4 2 0 0 2 2 2 2 N-terminal small S protein of HET, non-prionic HHA PF05321.11 KXX79303.1 - 0.14 12.5 0.1 0.9 9.9 0.1 2.2 2 0 0 2 2 2 0 Haemolysin expression modulating protein DUF956 PF06115.11 KXX79303.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF956) BCAS2 PF05700.11 KXX79304.1 - 1.4e-61 207.8 0.8 1.6e-61 207.6 0.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4407 PF14362.6 KXX79304.1 - 0.02 14.2 1.1 0.026 13.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KXX79304.1 - 0.06 13.6 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KXX79304.1 - 0.14 12.0 0.3 0.83 9.5 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator PMP1_2 PF08114.11 KXX79305.1 - 0.083 12.7 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Pyridoxal_deC PF00282.19 KXX79306.1 - 1.9e-23 82.8 0.0 2.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 KXX79306.1 - 0.0029 16.4 0.0 0.0039 15.9 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 KXX79306.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXX79306.1 - 0.039 13.2 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2462 PF09495.10 KXX79307.1 - 3.6e-15 56.4 10.5 5e-15 56.0 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) ArfGap PF01412.18 KXX79308.1 - 4.1e-38 130.1 0.5 6.4e-38 129.4 0.5 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf HAUS4 PF14735.6 KXX79308.1 - 0.26 11.0 0.0 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Methyltransf_23 PF13489.6 KXX79309.1 - 3.4e-16 59.5 0.0 7.5e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX79309.1 - 2.4e-09 37.8 0.0 5.5e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX79309.1 - 1.7e-05 25.4 0.0 0.00011 22.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX79309.1 - 1.9e-05 24.5 0.0 0.00014 21.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX79309.1 - 2.9e-05 24.6 0.0 5.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX79309.1 - 0.0028 17.2 0.0 0.033 13.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXX79309.1 - 0.02 14.2 0.0 0.18 11.1 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXX79309.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KXX79309.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase FTA4 PF13093.6 KXX79310.1 - 3.9e-74 248.9 0.0 4.6e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Peptidase_C2 PF00648.21 KXX79311.1 - 1.4e-64 218.0 0.7 7.9e-43 146.6 0.3 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease CRA PF06589.11 KXX79311.1 - 5.2 7.2 6.3 0.77 9.9 0.2 2.4 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) Ribosomal_S18 PF01084.20 KXX79312.1 - 2.7e-13 49.9 0.0 5.2e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 HTH_32 PF13565.6 KXX79312.1 - 0.32 11.6 7.1 0.79 10.4 4.2 2.5 2 1 0 2 2 2 0 Homeodomain-like domain PPR PF01535.20 KXX79313.1 - 3.5e-05 23.8 0.1 13 6.3 0.0 4.9 5 0 0 5 5 5 3 PPR repeat BTAD PF03704.17 KXX79313.1 - 0.00094 19.6 2.8 1.8 9.0 0.0 3.0 2 0 0 2 2 2 2 Bacterial transcriptional activator domain PPR_2 PF13041.6 KXX79313.1 - 0.0088 16.2 0.0 36 4.6 0.0 4.4 4 0 0 4 4 4 2 PPR repeat family Leuk-A4-hydro_C PF09127.11 KXX79313.1 - 0.24 11.5 1.1 3.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Leukotriene A4 hydrolase, C-terminal ATG7_N PF16420.5 KXX79314.1 - 1.5e-109 366.3 0.0 1.9e-109 365.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KXX79314.1 - 4.5e-45 153.9 0.0 7e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KXX79314.1 - 0.14 12.2 0.0 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.23 KXX79315.1 - 8.5e-28 96.2 2.0 1.3e-27 95.6 2.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXX79315.1 - 5.9e-12 45.5 0.2 9.7e-12 44.8 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KXX79315.1 - 5.6e-05 23.7 0.0 0.00014 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Egh16-like PF11327.8 KXX79316.1 - 6.3e-56 189.7 4.8 7.8e-56 189.4 4.8 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor ADH_N PF08240.12 KXX79317.1 - 1.3e-19 70.1 4.1 2.7e-19 69.1 4.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX79317.1 - 8.1e-16 58.2 0.0 1.7e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX79317.1 - 3.5e-05 24.9 0.0 7.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXX79317.1 - 0.041 13.2 0.1 0.066 12.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXX79317.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HET PF06985.11 KXX79318.1 - 1.1e-18 68.0 0.0 3.5e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HypA PF01155.19 KXX79318.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sugar_tr PF00083.24 KXX79319.1 - 2.3e-24 86.1 6.6 5.2e-19 68.4 3.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXX79319.1 - 2.1e-06 26.9 8.1 2.1e-06 26.9 8.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KXX79319.1 - 0.0087 15.1 4.6 0.013 14.5 4.6 1.4 1 0 0 1 1 1 1 Nucleoside H+ symporter Methyltransf_23 PF13489.6 KXX79320.1 - 7.5e-24 84.4 0.0 1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX79320.1 - 1.9e-10 41.3 0.0 4.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX79320.1 - 1.1e-07 31.8 0.0 1.3e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX79320.1 - 1.3e-07 32.2 0.0 2.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX79320.1 - 2e-06 28.4 0.0 1.2e-05 26.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX79320.1 - 0.00079 18.8 0.0 0.015 14.6 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXX79320.1 - 0.0013 18.6 0.1 0.033 13.9 0.1 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXX79320.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXX79320.1 - 0.029 14.5 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.15 KXX79320.1 - 0.048 13.0 0.0 0.81 9.0 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G eIF3g PF12353.8 KXX79321.1 - 8.7e-44 148.9 2.9 8.7e-44 148.9 2.9 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KXX79321.1 - 1.9e-15 56.4 0.1 3.8e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KXX79321.1 - 0.024 15.0 0.2 0.048 14.0 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 KXX79321.1 - 0.073 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif ADP_PFK_GK PF04587.15 KXX79321.1 - 0.13 10.8 0.1 0.18 10.3 0.1 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region PH PF00169.29 KXX79322.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 PH domain PEMT PF04191.13 KXX79323.1 - 3e-58 194.8 9.6 1.7e-36 124.8 1.6 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 KXX79323.1 - 0.092 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KXX79323.1 - 0.11 13.1 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 SKICH domain PBP_sp32 PF07222.12 KXX79324.1 - 0.62 9.5 4.4 0.76 9.2 4.4 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 adh_short PF00106.25 KXX79325.1 - 8.6e-23 80.8 0.0 8.6e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX79325.1 - 6.5e-14 52.1 0.0 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX79325.1 - 0.001 19.0 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Vfa1 PF08432.10 KXX79326.1 - 4.8e-58 196.5 18.7 5.4e-58 196.3 18.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 MTBP_N PF14918.6 KXX79326.1 - 0.051 13.0 6.4 0.18 11.2 6.4 1.8 1 1 0 1 1 1 0 MDM2-binding RR_TM4-6 PF06459.12 KXX79326.1 - 0.068 13.0 12.4 0.086 12.7 12.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCM_bind PF09739.9 KXX79326.1 - 0.083 11.3 7.3 0.096 11.1 7.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 KXX79326.1 - 0.5 9.1 12.5 0.57 8.9 12.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF908 PF06012.12 KXX79326.1 - 0.51 9.7 6.6 0.57 9.5 6.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ATP11 PF06644.11 KXX79326.1 - 2 8.1 15.3 2.6 7.8 15.3 1.1 1 0 0 1 1 1 0 ATP11 protein Sporozoite_P67 PF05642.11 KXX79326.1 - 4 5.4 13.1 4.9 5.1 13.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 KXX79326.1 - 5.1 5.5 12.2 5.4 5.4 12.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPL5 PF18168.1 KXX79326.1 - 5.3 6.2 12.2 6.6 5.9 12.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Ureide_permease PF07168.11 KXX79326.1 - 6.6 5.4 5.3 8.1 5.1 5.3 1.1 1 0 0 1 1 1 0 Ureide permease MAP7 PF05672.11 KXX79326.1 - 6.8 6.3 32.5 9.9 5.8 32.5 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF702 PF05142.12 KXX79326.1 - 8.3 6.9 10.2 7.4 7.0 8.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF702) MCU PF04678.13 KXX79327.1 - 8.3e-23 81.4 0.1 8.3e-23 81.4 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial calcium uniporter PI3K_1B_p101 PF10486.9 KXX79327.1 - 0.2 9.4 3.4 0.27 8.9 3.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SLM4 PF16818.5 KXX79328.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein SLM4 zf-C2H2 PF00096.26 KXX79328.1 - 0.97 10.0 25.3 0.33 11.5 2.5 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX79328.1 - 3.3 8.8 25.2 0.7 10.9 3.2 5.2 4 0 0 4 4 4 0 C2H2-type zinc finger DSPc PF00782.20 KXX79329.1 - 1.2e-15 57.5 0.0 7.6e-09 35.5 0.2 3.1 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXX79329.1 - 0.035 14.4 0.0 0.078 13.3 0.0 1.6 2 0 0 2 2 2 0 Rit1 DUSP-like domain Glyco_hydro_114 PF03537.13 KXX79330.1 - 6.8e-45 153.2 0.3 8.3e-45 152.9 0.3 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 HET PF06985.11 KXX79331.1 - 0.002 18.5 0.1 0.0029 17.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Alpha_L_fucos PF01120.17 KXX79332.1 - 8.5e-28 97.8 0.1 1.2e-27 97.3 0.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 KXX79332.1 - 3.9e-10 39.9 0.7 2.4e-09 37.4 0.0 2.5 2 1 0 2 2 2 1 F5/8 type C domain Sugar_tr PF00083.24 KXX79333.1 - 2.5e-22 79.4 21.8 2.1e-21 76.4 16.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter TraQ PF09679.10 KXX79333.1 - 0.099 12.6 0.4 0.25 11.3 0.4 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) ABC2_membrane_2 PF12679.7 KXX79333.1 - 7.4 5.7 9.5 36 3.5 9.5 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Tyrosinase PF00264.20 KXX79334.1 - 1.2e-45 156.6 1.7 1.5e-45 156.2 1.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 KXX79335.1 - 1.6e-13 50.3 41.6 1.2e-11 44.2 29.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyoxalase PF00903.25 KXX79336.1 - 0.0055 16.9 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CorA PF01544.18 KXX79338.1 - 6.2e-09 35.6 0.2 1.3e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cupin_2 PF07883.11 KXX79339.1 - 6.9e-11 41.7 0.0 1.6e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXX79339.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 KXX79339.1 - 0.17 11.6 0.0 0.48 10.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Alpha-amylase PF00128.24 KXX79340.1 - 6.2e-16 58.9 0.1 2e-15 57.2 0.2 1.7 2 1 0 2 2 2 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 KXX79340.1 - 0.00026 21.1 0.0 0.00057 20.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 KXX79340.1 - 0.014 13.6 0.0 0.63 8.2 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 70 ABC_tran PF00005.27 KXX79341.1 - 1.5e-25 90.3 0.0 2.4e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KXX79341.1 - 8e-12 45.0 5.5 1.6e-11 44.0 5.5 1.5 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KXX79341.1 - 0.00059 19.8 0.2 0.0011 18.9 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 KXX79341.1 - 0.037 13.4 1.0 0.058 12.7 1.0 1.2 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 KXX79341.1 - 0.048 13.4 0.7 0.1 12.3 0.7 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXX79341.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 KXX79341.1 - 0.11 12.1 0.1 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXX79341.1 - 0.19 11.8 0.3 0.36 10.9 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_11 PF08241.12 KXX79343.1 - 1e-09 38.9 0.0 2.6e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX79343.1 - 3.5e-08 34.0 0.0 1.5e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX79343.1 - 0.0022 17.4 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXX79343.1 - 0.028 15.1 0.0 0.05 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXX79343.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_8 PF13523.6 KXX79344.1 - 8.1e-44 148.8 0.1 1.2e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ORC6 PF05460.13 KXX79345.1 - 1.1 8.4 4.7 2 7.6 4.7 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Herpes_LMP2 PF07415.11 KXX79345.1 - 9.7 4.8 7.6 15 4.2 7.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein CVNH PF08881.10 KXX79346.1 - 1.5e-27 96.3 0.0 1.6e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 CVNH domain Rtt106 PF08512.12 KXX79347.1 - 5e-31 107.0 0.0 2.3e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KXX79347.1 - 0.015 15.3 0.0 0.076 13.0 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain HET PF06985.11 KXX79348.1 - 6.9e-25 88.1 0.0 1.2e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LAGLIDADG_2 PF03161.13 KXX79349.1 - 0.057 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family RELT PF12606.8 KXX79349.1 - 3.6 6.7 4.5 0.48 9.4 0.1 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 GMC_oxred_N PF00732.19 KXX79350.1 - 2e-60 204.7 0.0 2.5e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX79350.1 - 4.3e-38 131.1 0.1 9.8e-38 129.9 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX79350.1 - 4.2e-07 29.4 0.1 0.01 15.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXX79350.1 - 1.5e-05 24.7 1.1 0.00042 20.0 1.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXX79350.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXX79350.1 - 0.00028 21.1 0.3 0.00075 19.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX79350.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX79350.1 - 0.0012 18.2 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX79350.1 - 0.0019 17.5 0.4 0.0041 16.4 0.2 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXX79350.1 - 0.076 11.7 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KXX79350.1 - 0.088 13.4 0.7 4.6 7.9 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX79350.1 - 0.1 12.6 0.4 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KXX79350.1 - 0.16 12.2 0.5 0.47 10.7 0.2 1.9 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 KXX79350.1 - 0.17 11.1 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KXX79350.1 - 0.2 10.5 0.2 0.32 9.8 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase BATS PF06968.13 KXX79352.1 - 4.2e-24 84.5 0.6 1.3e-23 82.9 0.1 2.1 3 0 0 3 3 3 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KXX79352.1 - 3.8e-17 63.2 0.2 8e-17 62.1 0.2 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 KXX79353.1 - 9.2e-34 117.2 0.0 1.1e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3638 PF12340.8 KXX79354.1 - 5.5e-66 222.1 2.5 1e-57 195.1 0.0 3.4 3 1 1 4 4 4 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXX79354.1 - 2.8e-18 65.0 1.7 6e-18 63.9 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Dicty_CAR PF05462.11 KXX79355.1 - 7.8e-15 54.8 7.1 7.8e-15 54.8 7.1 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KXX79355.1 - 8.4e-08 32.2 12.1 1.8e-07 31.2 12.1 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXX79355.1 - 1.5e-06 27.7 0.7 2e-06 27.3 0.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FA_hydroxylase PF04116.13 KXX79356.1 - 3.3e-25 89.0 23.5 9e-25 87.6 21.7 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2109 PF09882.9 KXX79356.1 - 0.065 13.3 0.4 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) DUF4727 PF15856.5 KXX79356.1 - 0.069 12.7 0.4 0.26 10.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4727) DUF347 PF03988.12 KXX79357.1 - 0.0088 16.2 0.5 1.8 8.8 0.2 2.2 2 0 0 2 2 2 2 Repeat of Unknown Function (DUF347) SKG6 PF08693.10 KXX79357.1 - 0.014 14.8 5.6 0.014 14.8 5.6 1.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF3405 PF11885.8 KXX79358.1 - 1.2e-125 420.0 0.1 2.5e-125 419.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Aldose_epim PF01263.20 KXX79359.1 - 6e-50 170.2 0.1 7.1e-50 170.0 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Aminotran_3 PF00202.21 KXX79360.1 - 2.5e-41 141.7 0.0 2.9e-22 78.9 0.0 3.2 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KXX79360.1 - 1.9e-12 47.4 0.0 3.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thioredoxin_14 PF18402.1 KXX79360.1 - 0.059 13.3 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DIM1 PF02966.16 KXX79361.1 - 3.1e-67 224.4 0.3 3.4e-67 224.3 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KXX79361.1 - 0.002 18.1 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin FAD_binding_3 PF01494.19 KXX79362.1 - 2.4e-20 73.1 0.0 8.7e-10 38.4 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXX79362.1 - 0.00077 19.6 0.9 0.002 18.3 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXX79362.1 - 0.0032 16.4 0.6 0.031 13.1 0.4 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KXX79362.1 - 0.027 13.6 1.1 0.052 12.6 1.1 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KXX79362.1 - 0.093 12.3 6.1 0.042 13.4 2.8 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_67M PF07488.12 KXX79363.1 - 1.6e-146 487.5 0.0 2.3e-146 487.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KXX79363.1 - 3.9e-91 304.5 0.2 7.6e-91 303.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KXX79363.1 - 2.5e-27 95.6 0.0 7.1e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KXX79363.1 - 0.0024 18.7 0.1 0.014 16.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 DUF4448 PF14610.6 KXX79365.1 - 0.11 12.3 0.2 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Stevor PF17410.2 KXX79365.1 - 0.29 10.7 0.2 0.3 10.6 0.2 1.0 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Glyco_hydro_36 PF17167.4 KXX79367.1 - 1.5e-59 201.8 0.0 3.3e-59 200.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 KXX79367.1 - 1.9e-30 106.1 0.0 2.8e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Glyco_hydro_65C PF03633.15 KXX79367.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain Bac_rhamnosid6H PF17389.2 KXX79367.1 - 0.048 12.9 0.0 0.12 11.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Melibiase_2 PF16499.5 KXX79368.1 - 3.4e-53 180.6 5.7 1.6e-52 178.5 5.7 1.9 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 KXX79368.1 - 7.4e-07 28.4 0.0 1.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_C PF17801.1 KXX79368.1 - 0.014 15.5 0.0 0.058 13.5 0.0 2.0 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain MdcG PF10620.9 KXX79368.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG DUF1996 PF09362.10 KXX79369.1 - 5.1e-76 255.7 0.6 6.3e-76 255.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltransf_33 PF10017.9 KXX79370.1 - 2.9e-66 223.7 0.0 3.7e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent MetW PF07021.12 KXX79370.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KXX79370.1 - 0.23 11.2 0.0 0.53 10.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CBM_1 PF00734.18 KXX79372.1 - 2.2e-10 40.3 9.0 2.2e-10 40.3 9.0 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 KXX79372.1 - 1.8e-08 35.0 0.1 2.8e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.19 KXX79373.1 - 2e-13 50.4 0.0 3.2e-07 29.9 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Esterase_phd PF10503.9 KXX79374.1 - 6.3e-22 78.2 2.3 1.1e-21 77.4 2.3 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXX79374.1 - 4.8e-09 36.0 0.3 1.2e-08 34.7 0.3 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXX79374.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX79374.1 - 0.013 14.7 0.1 2 7.6 0.1 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 GMC_oxred_N PF00732.19 KXX79375.1 - 1.8e-60 204.8 0.0 2.3e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX79375.1 - 8.5e-33 113.9 0.1 1.7e-32 112.9 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KXX79375.1 - 5.9e-07 29.0 0.5 0.028 13.7 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX79375.1 - 2e-06 27.9 0.0 5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX79375.1 - 2.8e-06 26.8 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX79375.1 - 1.4e-05 24.9 0.0 0.00078 19.1 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX79375.1 - 4e-05 22.9 0.2 0.00019 20.6 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXX79375.1 - 0.00016 20.9 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KXX79375.1 - 0.001 17.9 0.1 0.013 14.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KXX79375.1 - 0.0011 18.2 0.1 0.0026 17.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 KXX79375.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Cdd1 PF11731.8 KXX79375.1 - 0.2 11.9 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus Mid2 PF04478.12 KXX79376.1 - 0.002 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KXX79376.1 - 0.41 10.1 2.9 0.34 10.4 0.5 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF2650 PF10853.8 KXX79376.1 - 1.5 8.6 5.4 0.18 11.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Skp1 PF01466.19 KXX79377.1 - 2.6e-20 72.3 0.6 5.8e-20 71.1 0.6 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXX79377.1 - 1.8e-07 31.2 0.1 5.2e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain IMS PF00817.20 KXX79377.1 - 0.0089 16.0 0.0 0.043 13.8 0.0 1.9 1 1 1 2 2 2 1 impB/mucB/samB family RGS PF00615.19 KXX79378.1 - 9.1e-07 29.2 0.0 1.5e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain Sld5 PF05916.11 KXX79379.1 - 1.1e-21 77.3 0.0 1.5e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.18 KXX79380.1 - 2.5e-37 127.1 0.0 3.9e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXX79380.1 - 6.2e-31 106.7 1.1 1e-30 106.0 1.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MFS_1 PF07690.16 KXX79381.1 - 1.5e-27 96.5 48.7 1.9e-26 92.8 48.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Pribosyltran PF00156.27 KXX79382.1 - 5.7e-23 81.2 0.2 1.4e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 KXX79382.1 - 7.6e-17 61.3 3.8 1.9e-16 60.1 3.8 1.7 1 0 0 1 1 1 1 FAD binding domain P-mevalo_kinase PF04275.14 KXX79382.1 - 1.2e-06 28.4 0.0 3.5e-06 26.9 0.0 1.8 1 1 1 2 2 2 1 Phosphomevalonate kinase UPRTase PF14681.6 KXX79382.1 - 0.00018 21.0 0.1 0.00036 20.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.12 KXX79382.1 - 0.0023 18.0 0.0 0.0069 16.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like RrnaAD PF00398.20 KXX79382.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FAD_binding_3 PF01494.19 KXX79383.1 - 1.8e-16 60.3 0.3 1.6e-15 57.2 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXX79383.1 - 0.0014 17.8 0.0 0.0033 16.5 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase HET PF06985.11 KXX79384.1 - 1.1e-32 113.4 0.2 1.7e-32 112.7 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3328 PF11807.8 KXX79386.1 - 7e-45 153.5 1.7 8e-45 153.3 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sulfate_transp PF00916.20 KXX79387.1 - 1.3e-79 267.7 6.7 1.8e-79 267.3 6.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXX79387.1 - 9.5e-17 60.7 0.0 2.3e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 KXX79387.1 - 0.0031 17.8 0.0 0.0077 16.6 0.0 1.8 1 0 0 1 1 1 1 STAS domain WBS28 PF15164.6 KXX79387.1 - 0.07 12.4 0.2 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF1286 PF06939.11 KXX79387.1 - 0.12 12.7 0.8 7.2 6.9 0.1 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1286) MFS_MOT1 PF16983.5 KXX79387.1 - 0.84 10.1 10.5 0.075 13.4 4.0 2.4 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF3636 PF12331.8 KXX79389.1 - 3.5e-46 156.7 0.0 6.8e-46 155.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) HTH_IclR PF09339.10 KXX79389.1 - 0.3 10.9 3.2 0.72 9.7 3.2 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain CEP63 PF17045.5 KXX79389.1 - 1.1 9.1 7.4 0.41 10.5 3.7 1.9 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF4407 PF14362.6 KXX79389.1 - 1.3 8.3 6.9 3 7.1 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LCD1 PF09798.9 KXX79389.1 - 3.1 6.2 5.0 1.6 7.1 0.1 2.6 3 0 0 3 3 3 0 DNA damage checkpoint protein DUF287 PF03384.14 KXX79389.1 - 5.6 7.4 7.3 0.88 10.0 0.1 2.6 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 CTP_transf_1 PF01148.20 KXX79390.1 - 3.2e-77 259.9 23.8 4e-77 259.6 23.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2304 PF10066.9 KXX79390.1 - 2.3 8.5 13.6 10 6.4 0.6 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Thiolase_N PF00108.23 KXX79391.1 - 1.2e-65 221.5 0.1 1.7e-65 221.0 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX79391.1 - 5.5e-40 135.8 0.2 1.1e-39 134.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXX79391.1 - 0.11 12.1 1.4 0.32 10.5 0.6 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain EF-hand_10 PF14788.6 KXX79391.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 EF hand Glyco_hydro_cc PF11790.8 KXX79392.1 - 1.3e-72 244.3 0.1 1.4e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MscL PF01741.18 KXX79393.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.1 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL KR PF08659.10 KXX79394.1 - 1.7e-55 187.7 1.0 1e-53 181.9 0.0 3.2 3 0 0 3 3 3 1 KR domain NAD_binding_4 PF07993.12 KXX79394.1 - 1.1e-25 90.3 0.0 2.6e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KXX79394.1 - 8.2e-19 68.2 0.0 2.3e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX79394.1 - 4.3e-14 52.4 0.0 3.9e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXX79394.1 - 1.3e-12 48.3 0.0 7e-12 45.9 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain PS-DH PF14765.6 KXX79394.1 - 1e-11 44.7 0.0 2.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_31 PF13847.6 KXX79394.1 - 7.8e-11 42.0 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX79394.1 - 1e-10 42.1 0.0 9.7e-10 39.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX79394.1 - 1.5e-10 41.1 0.0 3.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXX79394.1 - 1.2e-09 38.0 0.0 2.2e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 KXX79394.1 - 2.4e-07 30.3 0.0 4.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KXX79394.1 - 3.2e-07 30.2 0.1 6.9e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KXX79394.1 - 0.00032 21.0 0.2 0.001 19.4 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site HTH_38 PF13936.6 KXX79394.1 - 0.0048 16.6 3.4 0.97 9.3 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain 3Beta_HSD PF01073.19 KXX79394.1 - 0.0062 15.6 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 KXX79394.1 - 0.0094 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 KXX79394.1 - 0.032 13.9 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) GDP_Man_Dehyd PF16363.5 KXX79394.1 - 0.041 13.3 0.0 7.8 5.8 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AATase PF07247.12 KXX79395.1 - 1.2e-18 66.9 0.0 1.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KXX79395.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DNase_NucA_NucB PF14040.6 KXX79398.1 - 1.5e-38 131.7 0.7 2.3e-38 131.1 0.7 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF805 PF05656.14 KXX79399.1 - 0.98 9.9 6.5 0.11 12.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF805) p47_phox_C PF08944.11 KXX79399.1 - 1.6 8.2 3.7 2.8 7.4 3.7 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain AIG1 PF04548.16 KXX79400.1 - 1.3e-10 41.0 0.1 5.7e-10 38.9 0.0 1.8 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 KXX79400.1 - 4e-10 39.8 0.1 1.4e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXX79400.1 - 0.0063 17.0 5.4 0.11 13.0 5.4 2.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXX79400.1 - 0.0077 16.1 0.1 0.021 14.7 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase SRPRB PF09439.10 KXX79400.1 - 0.0088 15.5 1.4 0.15 11.5 0.0 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KXX79400.1 - 0.04 14.5 3.4 0.14 12.8 0.6 3.0 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 KXX79400.1 - 0.047 14.1 2.3 0.34 11.3 0.2 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXX79400.1 - 0.051 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KXX79400.1 - 0.055 13.5 4.3 2.1 8.4 0.0 2.9 2 2 1 3 3 3 0 Dynamin family SRP54 PF00448.22 KXX79400.1 - 0.064 12.9 1.4 3.1 7.4 0.6 2.7 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain CorA PF01544.18 KXX79400.1 - 0.078 12.3 3.4 0.12 11.7 3.4 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein FeoB_N PF02421.18 KXX79400.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_23 PF13476.6 KXX79400.1 - 0.35 11.3 4.7 13 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXX79400.1 - 0.99 9.1 3.8 1.7 8.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXX79400.1 - 1.6 8.8 8.2 16 5.5 8.2 2.5 1 1 0 1 1 1 0 Helicase HerA, central domain cwf21 PF08312.12 KXX79400.1 - 4.1 7.6 6.6 0.7 10.1 0.2 2.9 2 2 0 2 2 2 0 cwf21 domain M PF02370.16 KXX79400.1 - 4.1 8.3 6.9 6.2 7.7 1.8 2.9 2 0 0 2 2 2 0 M protein repeat DUF3481 PF11980.8 KXX79401.1 - 0.12 12.1 0.2 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Phage_P2_GpU PF06995.11 KXX79401.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Phage P2 GpU DUF3328 PF11807.8 KXX79402.1 - 5.9e-30 104.7 0.0 7.4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Transferase PF02458.15 KXX79403.1 - 3.2e-22 78.8 0.0 4.3e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family Cutinase PF01083.22 KXX79404.1 - 1.3e-56 191.3 4.9 1.5e-56 191.1 4.9 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXX79404.1 - 2.3e-06 27.4 0.1 3e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 KXX79404.1 - 0.012 16.2 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX79404.1 - 0.013 15.2 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold VirJ PF06057.11 KXX79404.1 - 0.07 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Palm_thioest PF02089.15 KXX79404.1 - 0.1 12.4 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase p450 PF00067.22 KXX79405.1 - 4.6e-60 203.7 0.0 6.3e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 KXX79405.1 - 0.12 12.1 0.1 0.64 9.7 0.0 1.9 2 0 0 2 2 2 0 TUP1-like enhancer of split LXG PF04740.12 KXX79406.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily Fungal_trans_2 PF11951.8 KXX79408.1 - 9.5e-08 31.2 0.7 9e-07 28.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX79408.1 - 6.2e-07 29.4 8.9 9.6e-07 28.8 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Collagen PF01391.18 KXX79408.1 - 0.027 14.2 2.7 0.051 13.3 2.7 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) p450 PF00067.22 KXX79409.1 - 1.5e-48 165.7 0.0 2e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KXX79409.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 Abhydrolase_3 PF07859.13 KXX79410.1 - 5.5e-35 121.1 0.0 6.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KXX79410.1 - 0.0025 17.4 0.0 0.11 12.0 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KXX79410.1 - 0.0053 16.4 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 KXX79410.1 - 0.016 14.7 1.4 0.72 9.3 0.1 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KXX79410.1 - 0.034 13.9 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KXX79410.1 - 0.062 12.9 1.7 1.7 8.2 1.8 2.1 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 KXX79410.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KXX79410.1 - 0.2 11.1 0.0 0.75 9.2 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family GTP_cyclohydroI PF01227.22 KXX79411.1 - 1.4e-71 239.7 0.5 1.6e-71 239.4 0.5 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KXX79411.1 - 0.00049 20.2 0.0 0.0022 18.1 0.0 2.0 2 0 0 2 2 2 1 QueF-like protein ADP_ribosyl_GH PF03747.14 KXX79412.1 - 3e-65 220.9 7.2 3.4e-65 220.7 7.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.15 KXX79412.1 - 0.062 13.2 2.3 5.2 7.0 0.8 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF4360 PF14273.6 KXX79413.1 - 4.8e-45 153.6 0.3 5.7e-45 153.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Aldedh PF00171.22 KXX79414.1 - 2.7e-138 461.3 0.0 3.1e-138 461.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KXX79414.1 - 0.0079 16.2 0.1 0.021 14.8 0.1 1.7 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Amidohydro_2 PF04909.14 KXX79415.1 - 8.9e-46 157.0 1.4 1.2e-45 156.6 1.4 1.1 1 0 0 1 1 1 1 Amidohydrolase HTH_39 PF14090.6 KXX79415.1 - 0.098 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HRG PF16954.5 KXX79416.1 - 0.013 15.8 0.1 0.027 14.9 0.1 1.5 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Amidohydro_3 PF07969.11 KXX79417.1 - 3e-55 188.6 7.4 6.9e-55 187.4 7.4 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXX79417.1 - 7.3e-06 25.5 0.6 0.43 9.9 0.0 3.3 3 1 0 3 3 3 3 Amidohydrolase family Ribosomal_L44 PF00935.19 KXX79418.1 - 9.5e-37 125.3 10.8 1.3e-36 124.9 10.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.11 KXX79418.1 - 0.014 15.5 1.5 0.014 15.5 1.5 2.2 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like CorA PF01544.18 KXX79419.1 - 3.6e-05 23.2 0.3 7.1e-05 22.3 0.3 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2339 PF10101.9 KXX79419.1 - 0.017 13.7 0.4 0.022 13.4 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF5494 PF17598.2 KXX79419.1 - 0.036 14.2 0.4 0.58 10.3 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5494) 2OG-FeII_Oxy_3 PF13640.6 KXX79420.1 - 4.1e-09 37.2 0.3 2.8e-08 34.5 0.3 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KXX79421.1 - 6.9e-26 91.5 0.0 1.4e-25 90.5 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family NAD_binding_3 PF03447.16 KXX79421.1 - 0.13 12.9 0.0 0.19 12.4 0.0 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain HMG-CoA_red PF00368.18 KXX79422.1 - 1.2e-141 472.0 7.3 1.6e-141 471.6 7.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KXX79422.1 - 1.8e-48 164.3 1.9 3.3e-48 163.5 1.9 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KXX79422.1 - 1e-12 48.2 5.0 9.6e-12 45.0 5.0 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXX79422.1 - 5.5e-05 21.5 1.2 8.8e-05 20.8 1.2 1.2 1 0 0 1 1 1 1 Patched family MFS_1 PF07690.16 KXX79423.1 - 2.3e-41 141.9 55.3 2.3e-41 141.9 55.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX79423.1 - 4.6e-17 62.0 4.0 4.6e-17 62.0 4.0 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXX79423.1 - 5.1e-17 61.5 17.5 7.7e-17 60.9 17.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Esterase_phd PF10503.9 KXX79424.1 - 2.8e-24 85.9 1.0 4.2e-24 85.3 1.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXX79424.1 - 1.4e-13 50.8 0.6 2.2e-13 50.2 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.18 KXX79424.1 - 3.7e-11 42.8 11.8 3.7e-11 42.8 11.8 3.2 4 0 0 4 4 4 1 Fungal cellulose binding domain Abhydrolase_2 PF02230.16 KXX79424.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KXX79424.1 - 0.019 14.6 1.6 0.045 13.4 1.7 1.5 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KXX79424.1 - 0.02 14.6 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KXX79424.1 - 0.035 14.0 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXX79424.1 - 0.047 13.3 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KXX79424.1 - 0.13 11.8 0.2 0.34 10.4 0.2 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family AMP-binding PF00501.28 KXX79425.1 - 2.2e-73 247.3 0.0 3.7e-73 246.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXX79425.1 - 8.8e-72 241.4 0.0 1.2e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXX79425.1 - 1.5e-10 41.0 0.0 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXX79425.1 - 7.7e-10 39.0 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KXX79425.1 - 4.5e-09 35.7 0.3 1.9e-08 33.7 0.3 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KXX79425.1 - 2.9e-05 25.0 0.0 0.0003 21.7 0.0 2.8 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 KXX79425.1 - 0.0005 20.0 0.3 0.0026 17.7 0.3 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXX79425.1 - 0.0025 17.0 0.0 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX79425.1 - 0.054 12.9 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cleaved_Adhesin PF07675.11 KXX79425.1 - 0.084 12.8 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Cleaved Adhesin Domain Piwi PF02171.17 KXX79425.1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Piwi domain RmlD_sub_bind PF04321.17 KXX79425.1 - 0.13 11.3 0.0 0.49 9.5 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain PAP2 PF01569.21 KXX79426.1 - 4.1e-13 49.3 0.1 6.8e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily SUR7 PF06687.12 KXX79428.1 - 9.4e-25 87.5 1.3 1.2e-24 87.2 1.3 1.0 1 0 0 1 1 1 1 SUR7/PalI family LYRIC PF15686.5 KXX79428.1 - 0.0013 18.4 0.4 0.0018 17.9 0.4 1.2 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family TNFR_16_TM PF18422.1 KXX79428.1 - 0.019 14.9 0.8 0.052 13.5 0.8 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF4381 PF14316.6 KXX79428.1 - 0.088 13.1 1.1 0.2 11.9 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4149 PF13664.6 KXX79428.1 - 0.93 9.8 8.5 0.11 12.8 1.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Fig1 PF12351.8 KXX79428.1 - 1.3 8.9 7.1 2.5 8.0 7.1 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Yip1 PF04893.17 KXX79428.1 - 1.5 8.6 18.7 0.4 10.4 14.2 1.9 2 0 0 2 2 2 0 Yip1 domain TPR_2 PF07719.17 KXX79429.1 - 4.9e-13 48.1 4.6 9.2e-05 22.3 0.2 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX79429.1 - 5.8e-09 35.4 2.9 0.039 13.8 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat SET PF00856.28 KXX79429.1 - 1.1e-08 35.6 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 SET domain TPR_19 PF14559.6 KXX79429.1 - 3.7e-05 24.2 2.6 1.6 9.3 0.6 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXX79429.1 - 6.8e-05 22.8 3.2 0.64 10.4 0.5 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX79429.1 - 0.0011 19.2 3.9 1.6 9.0 0.4 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX79429.1 - 0.0028 18.3 4.5 1.2 10.1 1.6 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX79429.1 - 0.0099 15.9 0.2 0.53 10.4 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX79429.1 - 0.12 13.0 2.4 0.43 11.3 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXX79429.1 - 0.13 12.7 3.5 23 5.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Acetyltransf_7 PF13508.7 KXX79430.1 - 0.00046 20.6 0.0 0.00081 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX79430.1 - 0.00078 19.7 0.0 0.0013 19.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX79430.1 - 0.0038 17.1 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NACHT PF05729.12 KXX79431.1 - 2.5e-07 30.8 0.1 1.2e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 KXX79431.1 - 7.2e-07 28.8 0.2 1.3e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KXX79431.1 - 0.00015 22.1 0.0 0.00061 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX79431.1 - 0.00036 20.9 0.0 0.0016 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KXX79431.1 - 0.016 15.6 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KXX79431.1 - 0.02 15.4 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXX79431.1 - 0.088 12.5 0.6 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXX79431.1 - 0.1 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 KXX79432.1 - 4.3e-75 252.5 0.0 6.6e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79432.1 - 5.3e-37 127.5 0.0 1.1e-36 126.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX79432.1 - 0.0002 20.8 0.2 0.69 9.2 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KXX79432.1 - 0.00098 18.0 3.6 0.0043 15.9 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 KXX79432.1 - 0.0042 16.1 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXX79432.1 - 0.014 15.4 0.8 0.034 14.1 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family adh_short_C2 PF13561.6 KXX79433.1 - 1.7e-30 106.3 3.5 2.8e-21 76.1 0.6 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX79433.1 - 1.4e-14 54.0 0.4 4.3e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_25 PF13649.6 KXX79433.1 - 4.4e-05 24.1 0.1 0.00017 22.2 0.0 2.0 2 1 1 3 3 2 1 Methyltransferase domain Epimerase PF01370.21 KXX79433.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXX79433.1 - 0.00027 20.9 0.2 0.00069 19.6 0.1 1.7 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 KXX79433.1 - 0.0018 17.4 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family B12-binding PF02310.19 KXX79433.1 - 0.023 14.7 0.1 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain ApbA PF02558.16 KXX79433.1 - 0.024 14.3 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.12 KXX79433.1 - 0.05 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 KXX79433.1 - 0.062 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_11 PF08241.12 KXX79433.1 - 0.13 12.9 0.1 0.42 11.3 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KXX79433.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KXX79433.1 - 1.2 8.6 5.3 3.2 7.2 0.9 2.6 1 1 1 3 3 3 0 FAD dependent oxidoreductase GFO_IDH_MocA PF01408.22 KXX79434.1 - 8.3e-19 68.6 0.0 1.6e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXX79434.1 - 1.6e-09 37.8 0.0 3.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KXX79434.1 - 0.022 15.4 0.0 0.039 14.6 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fib_alpha PF08702.10 KXX79435.1 - 0.027 14.7 1.3 1.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family WSC PF01822.19 KXX79436.1 - 9.8e-15 54.5 7.4 1.8e-14 53.7 7.4 1.5 1 0 0 1 1 1 1 WSC domain DUF3433 PF11915.8 KXX79437.1 - 2.2e-36 124.2 13.4 1.1e-21 77.1 6.6 4.6 7 0 0 7 7 7 2 Protein of unknown function (DUF3433) Ig_C17orf99 PF17736.1 KXX79437.1 - 0.018 15.1 0.3 1.8 8.7 0.1 2.7 1 1 1 2 2 2 0 C17orf99 Ig domain Glyco_hydro_3_C PF01915.22 KXX79438.1 - 3.4e-38 131.6 0.0 1.2e-37 129.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX79438.1 - 3.9e-28 98.8 0.0 5.9e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX79438.1 - 1.2e-06 28.5 0.0 3.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.21 KXX79439.1 - 0.00015 21.8 8.1 0.00015 21.8 8.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXX79439.1 - 0.0082 16.2 10.8 0.0082 16.2 10.8 1.9 2 0 0 2 2 2 1 Basic region leucine zipper DUF349 PF03993.12 KXX79439.1 - 0.034 14.4 4.9 0.062 13.6 4.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) PGBA_C PF15437.6 KXX79439.1 - 0.21 12.0 4.2 0.41 11.0 4.2 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DUF4551 PF15087.6 KXX79439.1 - 1.3 7.8 3.3 1.7 7.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SET PF00856.28 KXX79440.1 - 4.2e-14 53.3 0.1 2e-13 51.1 0.0 2.2 2 1 0 2 2 2 1 SET domain SAF PF08666.12 KXX79440.1 - 0.0064 17.1 0.0 4 8.1 0.0 2.3 2 0 0 2 2 2 2 SAF domain DUF2225 PF09986.9 KXX79440.1 - 0.022 14.5 0.9 0.095 12.4 0.9 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_12 PF13424.6 KXX79440.1 - 0.067 13.5 2.8 0.13 12.6 2.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FliT PF05400.13 KXX79440.1 - 0.38 11.6 3.1 17 6.3 0.1 2.5 2 0 0 2 2 2 0 Flagellar protein FliT Hemerythrin PF01814.23 KXX79441.1 - 2.4e-08 34.6 0.2 3.3e-08 34.2 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain EcoR124_C PF12008.8 KXX79441.1 - 0.12 12.1 0.5 0.16 11.6 0.5 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal APAF1_C PF17908.1 KXX79441.1 - 0.17 11.9 0.4 0.24 11.4 0.4 1.3 1 0 0 1 1 1 0 APAF-1 helical domain Fungal_trans_2 PF11951.8 KXX79442.1 - 2.9e-52 177.8 1.6 3.7e-52 177.4 1.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX79442.1 - 9.9e-08 32.0 5.8 9.9e-08 32.0 5.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 KXX79443.1 - 3.1e-42 144.5 0.0 3.9e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.12 KXX79444.1 - 1.9e-127 425.3 0.0 2.1e-127 425.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KXX79444.1 - 4.9e-05 23.9 0.0 0.0051 17.4 0.0 2.7 2 0 0 2 2 2 1 Replication protein A C terminal HTH_34 PF13601.6 KXX79444.1 - 0.057 13.6 0.1 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_36 PF13730.6 KXX79444.1 - 0.058 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SUB1_ProdP9 PF18213.1 KXX79444.1 - 0.18 11.7 0.2 22 5.0 0.0 2.8 3 0 0 3 3 3 0 SUB1 protease Prodomain ProdP9 Rio2_N PF09202.11 KXX79444.1 - 0.2 11.9 0.0 0.6 10.4 0.0 1.7 1 0 0 1 1 1 0 Rio2, N-terminal MARVEL PF01284.23 KXX79445.1 - 4e-05 23.7 14.2 9.3e-05 22.5 14.2 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF2818 PF10993.8 KXX79445.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) Tetraspanin PF00335.20 KXX79445.1 - 0.46 10.2 5.8 1.8 8.2 3.3 2.1 2 0 0 2 2 2 0 Tetraspanin family FtsX PF02687.21 KXX79445.1 - 0.68 10.4 11.2 2.7 8.5 7.7 2.3 2 0 0 2 2 2 0 FtsX-like permease family DUF2070 PF09843.9 KXX79445.1 - 7.4 4.7 6.7 9.2 4.4 6.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ENTH PF01417.20 KXX79446.1 - 1.5e-47 160.7 0.2 2.4e-47 160.1 0.2 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KXX79446.1 - 0.00015 20.8 0.2 0.00021 20.4 0.2 1.1 1 0 0 1 1 1 1 ANTH domain GRP PF07172.11 KXX79446.1 - 0.072 13.8 19.2 0.15 12.8 19.2 1.5 1 0 0 1 1 1 0 Glycine rich protein family DUF2477 PF10631.9 KXX79446.1 - 6.9 7.3 6.0 29 5.3 6.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) TPR_1 PF00515.28 KXX79448.1 - 4.3e-44 146.6 26.5 2.2e-05 24.1 0.2 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat STI1 PF17830.1 KXX79448.1 - 8.8e-37 124.8 15.2 3.5e-20 71.7 2.5 3.1 4 0 0 4 4 3 2 STI1 domain TPR_2 PF07719.17 KXX79448.1 - 5.1e-36 119.9 23.8 6.6e-05 22.7 0.0 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 KXX79448.1 - 5.7e-20 70.7 27.3 0.00056 19.5 0.6 8.4 8 1 1 9 9 9 4 TPR repeat TPR_12 PF13424.6 KXX79448.1 - 6.9e-16 58.3 13.5 7.5e-10 39.0 0.4 6.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX79448.1 - 1.1e-14 54.8 9.8 0.0033 18.0 0.1 6.0 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXX79448.1 - 1.1e-14 53.3 21.8 0.012 15.7 0.1 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXX79448.1 - 1.2e-14 53.8 3.9 0.91 10.5 0.0 8.5 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX79448.1 - 2.1e-13 50.6 10.8 0.028 14.9 0.1 6.7 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXX79448.1 - 4.7e-13 48.5 8.5 1 9.9 0.4 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXX79448.1 - 5.7e-11 42.4 0.1 0.00058 20.0 0.0 3.7 5 0 0 5 5 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX79448.1 - 1.9e-10 40.0 8.3 0.03 14.3 0.0 6.5 7 1 0 7 7 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXX79448.1 - 0.00013 21.7 15.8 0.19 11.6 0.1 7.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX79448.1 - 0.0013 18.2 0.5 0.022 14.1 0.0 2.7 3 0 0 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 KXX79448.1 - 0.0037 17.8 13.7 1.8 9.4 0.1 7.4 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXX79448.1 - 0.005 16.9 3.9 8 6.6 0.1 4.9 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat GerD PF17898.1 KXX79448.1 - 0.0071 16.3 6.9 0.16 11.9 2.9 3.3 2 1 0 2 2 2 1 Spore germination GerD central core domain TPR_3 PF07720.12 KXX79448.1 - 0.015 15.2 8.8 18 5.4 0.2 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX79448.1 - 0.13 12.5 8.5 2.7 8.3 1.2 3.7 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KXX79448.1 - 0.18 11.9 15.0 10 6.3 0.2 6.4 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain DUF5113 PF17140.4 KXX79448.1 - 0.55 10.0 6.7 7.3 6.4 0.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) ANAPC8 PF04049.13 KXX79448.1 - 1.1 9.2 6.1 0.43 10.6 0.2 2.5 2 1 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 XPC-binding PF09280.11 KXX79448.1 - 1.3 8.8 6.7 11 5.8 0.4 3.5 3 0 0 3 3 3 0 XPC-binding domain DUF5486 PF17588.2 KXX79448.1 - 2.1 8.3 4.3 8.9 6.3 1.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5486) MFS_1 PF07690.16 KXX79449.1 - 2.6e-32 112.1 19.3 2.6e-32 112.1 19.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.9 KXX79450.1 - 2.3e-19 70.0 2.2 2.3e-19 70.0 2.2 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BUD22 PF09073.10 KXX79450.1 - 0.34 10.2 29.1 0.44 9.8 29.1 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KXX79450.1 - 0.48 9.8 32.2 0.64 9.4 32.2 1.1 1 0 0 1 1 1 0 SDA1 Dicty_REP PF05086.12 KXX79450.1 - 1.3 6.9 6.3 1.8 6.4 6.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PBP_sp32 PF07222.12 KXX79450.1 - 6.3 6.2 11.6 1.1 8.6 8.0 1.5 1 1 1 2 2 2 0 Proacrosin binding protein sp32 AMPK1_CBM PF16561.5 KXX79451.1 - 3.2e-06 27.2 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase APH PF01636.23 KXX79452.1 - 4.9e-06 26.6 0.2 1e-05 25.6 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXX79452.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase DUF2040 PF09745.9 KXX79453.1 - 1.7e-36 124.9 25.4 1.7e-36 124.9 25.4 3.6 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) zf-Tim10_DDP PF02953.15 KXX79454.1 - 1.3e-19 69.6 1.8 1.8e-19 69.1 1.8 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FlgM PF04316.13 KXX79454.1 - 0.024 15.0 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF3361 PF11841.8 KXX79454.1 - 0.032 14.2 0.4 0.17 11.8 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3361) DUF2116 PF09889.9 KXX79454.1 - 0.11 12.5 1.2 0.14 12.1 0.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Actin PF00022.19 KXX79455.1 - 7.7e-27 93.9 0.0 3.5e-18 65.4 0.0 2.5 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KXX79455.1 - 0.00013 21.3 0.7 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KXX79455.1 - 0.0049 17.3 0.0 0.028 14.8 0.0 2.3 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 KXX79455.1 - 0.027 13.3 0.0 0.57 8.9 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein PI-PLC-X PF00388.19 KXX79456.1 - 5.4e-63 210.9 0.0 8.1e-63 210.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXX79456.1 - 2.2e-43 147.2 0.3 8.7e-43 145.3 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF4451 PF14616.6 KXX79457.1 - 8.2e-24 84.1 0.1 1.5e-23 83.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Med3 PF11593.8 KXX79457.1 - 0.44 9.7 30.1 0.95 8.6 30.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GREB1 PF15782.5 KXX79457.1 - 9.7 3.1 9.9 15 2.6 9.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM75 PF14650.6 KXX79458.1 - 8.9 5.7 12.7 12 5.4 12.7 1.1 1 0 0 1 1 1 0 FAM75 family Iso_dh PF00180.20 KXX79459.1 - 7.2e-110 367.4 0.0 1.3e-74 251.4 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.29 KXX79460.1 - 1.1e-09 38.0 7.2 1.8e-09 37.3 7.2 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXX79460.1 - 0.0014 18.1 4.1 0.0023 17.4 4.1 1.3 1 0 0 1 1 1 1 PHD-finger PNRC PF15365.6 KXX79461.1 - 2.1e-08 33.7 7.8 2.1e-08 33.7 7.8 5.0 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif Gti1_Pac2 PF09729.9 KXX79462.1 - 6.5e-40 137.1 9.7 6.1e-34 117.7 0.1 3.3 2 2 1 3 3 3 2 Gti1/Pac2 family GIDA_assoc PF13932.6 KXX79463.1 - 4.7e-20 72.7 0.0 6.3e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 GidA associated domain CorA PF01544.18 KXX79464.1 - 2.7e-42 145.1 0.0 4e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.13 KXX79465.1 - 6.9e-31 106.2 0.6 8.6e-31 105.8 0.6 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Neurensin PF14927.6 KXX79465.1 - 2.2 8.0 3.9 19 5.0 0.1 2.1 1 1 1 2 2 2 0 Neurensin zf-rbx1 PF12678.7 KXX79466.1 - 7.3e-25 87.0 12.9 9.9e-25 86.6 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXX79466.1 - 4.9e-17 61.8 9.8 6.3e-17 61.4 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXX79466.1 - 3.9e-06 27.1 14.1 0.00014 22.1 14.1 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX79466.1 - 0.0016 18.2 14.3 0.0025 17.6 8.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX79466.1 - 0.0017 18.2 11.6 0.03 14.2 11.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX79466.1 - 0.2 11.5 10.7 0.61 10.0 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXX79466.1 - 0.31 10.8 15.8 26 4.7 15.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KXX79466.1 - 0.4 10.7 6.8 1.5 8.9 6.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KXX79466.1 - 1.1 9.5 9.4 6 7.1 9.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXX79466.1 - 1.4 8.6 15.0 0.33 10.6 4.9 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXX79466.1 - 6.3 6.9 12.1 54 3.9 12.1 2.5 1 1 0 1 1 1 0 zinc-RING finger domain Tyr-DNA_phospho PF06087.12 KXX79467.1 - 1.1e-73 248.5 0.0 1.4e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KXX79467.1 - 1.1e-05 25.4 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain CDP-OH_P_transf PF01066.21 KXX79468.1 - 8.2e-14 52.1 0.8 8.2e-14 52.1 0.8 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-Tim10_DDP PF02953.15 KXX79469.1 - 6e-21 73.9 2.1 7.8e-21 73.5 2.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Spore_III_AB PF09548.10 KXX79469.1 - 0.071 13.2 0.3 0.085 13.0 0.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_L23eN PF03939.13 KXX79470.1 - 1.7e-23 82.5 14.2 1.7e-23 82.5 14.2 2.0 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KXX79470.1 - 1.1e-13 51.4 0.3 1.1e-13 51.4 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 DUF3326 PF11805.8 KXX79470.1 - 0.012 14.5 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Bmt2 PF11968.8 KXX79471.1 - 1e-93 313.2 0.0 1.3e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KXX79471.1 - 0.0079 16.0 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Hydrolase_like PF13242.6 KXX79472.1 - 0.008 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DeoC PF01791.9 KXX79472.1 - 0.036 13.7 0.0 8 6.0 0.0 2.1 2 0 0 2 2 2 0 DeoC/LacD family aldolase HAD_2 PF13419.6 KXX79472.1 - 0.068 13.3 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX79472.1 - 0.097 12.9 0.0 0.69 10.2 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KXX79472.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Pkinase PF00069.25 KXX79473.1 - 9.5e-55 185.8 0.0 1.4e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79473.1 - 1.1e-33 116.7 0.0 1.5e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX79473.1 - 1.8e-13 50.5 0.0 3.5e-10 39.7 0.0 2.9 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 KXX79473.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX79473.1 - 0.027 14.4 0.1 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF5485 PF17586.2 KXX79473.1 - 0.065 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5485) Aa_trans PF01490.18 KXX79474.1 - 7.8e-60 202.7 29.3 9.7e-60 202.4 29.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DEAD PF00270.29 KXX79475.1 - 8.6e-30 103.8 0.0 1.4e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX79475.1 - 3.3e-20 72.5 0.0 2.3e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX79475.1 - 4.2e-06 26.9 0.0 2.2e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CorA PF01544.18 KXX79476.1 - 2.2e-05 23.9 2.8 2.2e-05 23.9 2.8 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein His_Phos_1 PF00300.22 KXX79477.1 - 8.5e-20 71.3 0.0 1.8e-19 70.2 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF5102 PF17104.5 KXX79478.1 - 0.23 11.5 0.1 0.23 11.5 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5102) Iwr1 PF08574.10 KXX79479.1 - 2.2e-10 41.4 11.8 2.2e-10 41.4 11.8 2.2 2 0 0 2 2 2 1 Transcription factor Iwr1 DUF4598 PF15370.6 KXX79479.1 - 0.017 15.6 0.7 0.038 14.5 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) SH3_4 PF06347.13 KXX79480.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain RabGAP-TBC PF00566.18 KXX79481.1 - 2.4e-24 86.2 0.1 3.8e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PBD PF00786.28 KXX79482.1 - 0.01 16.1 0.1 0.045 14.1 0.1 2.1 1 0 0 1 1 1 0 P21-Rho-binding domain Pkinase PF00069.25 KXX79483.1 - 3.7e-74 249.4 0.0 6e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79483.1 - 1.3e-37 129.5 0.0 2.3e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX79483.1 - 4.9e-08 32.6 0.0 8.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TFIIA PF03153.13 KXX79483.1 - 0.12 12.3 33.7 0.16 11.9 33.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK5_activator PF03261.15 KXX79483.1 - 5.3 6.5 8.4 8 5.9 8.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Lectin_leg-like PF03388.13 KXX79484.1 - 1.5e-66 224.0 0.0 2e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KXX79484.1 - 1.4e-06 28.4 0.1 2e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KXX79484.1 - 1e-05 25.2 0.0 0.061 12.8 0.0 2.4 3 0 0 3 3 3 2 Legume lectin domain ATG27 PF09451.10 KXX79484.1 - 0.039 13.8 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 TPR_12 PF13424.6 KXX79486.1 - 1.3e-23 83.0 9.9 6.3e-08 32.8 0.2 5.1 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX79486.1 - 3e-09 36.3 4.0 0.56 10.1 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXX79486.1 - 8e-07 28.7 16.9 0.089 12.7 0.2 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX79486.1 - 2.4e-06 27.2 8.7 13 6.2 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX79486.1 - 1.4e-05 24.9 4.6 2.2 8.7 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX79486.1 - 5.3e-05 23.0 4.9 6.7 7.0 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat MitMem_reg PF13012.6 KXX79486.1 - 0.15 12.5 0.0 0.51 10.8 0.0 2.0 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function TPR_11 PF13414.6 KXX79486.1 - 2.9 7.7 10.3 27 4.6 0.0 5.5 7 0 0 7 7 7 0 TPR repeat MFS_1 PF07690.16 KXX79487.1 - 5.5e-34 117.6 67.8 4.1e-21 75.3 32.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PNP_UDP_1 PF01048.20 KXX79488.1 - 1.1e-10 41.2 0.1 2.4e-10 40.1 0.1 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily DUF5560 PF17715.1 KXX79488.1 - 0.16 11.4 1.6 0.81 9.1 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5560) Ank PF00023.30 KXX79489.1 - 4.3e-17 61.7 0.0 9.1e-06 25.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KXX79489.1 - 1.6e-15 57.3 0.1 4.6e-07 30.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX79489.1 - 9.2e-14 51.8 0.1 8.2e-13 48.8 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX79489.1 - 2.9e-09 37.0 0.2 3e-07 30.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX79489.1 - 2.1e-08 33.8 0.0 0.034 14.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF5561 PF17716.1 KXX79489.1 - 0.014 14.7 0.1 2.6 7.3 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5561) XPC-binding PF09280.11 KXX79489.1 - 0.059 13.1 0.9 3.6 7.4 0.1 2.3 2 0 0 2 2 2 0 XPC-binding domain Yippee-Mis18 PF03226.14 KXX79490.1 - 2.1e-18 66.5 0.0 3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Peptidase_M20 PF01546.28 KXX79491.1 - 2.5e-34 118.8 0.0 3.3e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXX79491.1 - 5.3e-13 48.8 0.0 8.5e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain APH PF01636.23 KXX79492.1 - 1.2e-05 25.4 0.0 5.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-RING_2 PF13639.6 KXX79493.1 - 5.7e-14 52.2 16.5 1e-13 51.4 5.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KXX79493.1 - 4.7e-10 39.0 2.2 4.7e-10 39.0 2.2 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXX79493.1 - 4.3e-09 36.1 17.7 7.3e-09 35.3 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX79493.1 - 7e-09 35.4 12.6 8.4e-07 28.8 3.8 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXX79493.1 - 3.1e-07 30.6 5.3 3.1e-07 30.6 5.3 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXX79493.1 - 1.6e-06 27.9 12.5 5.8e-06 26.2 3.8 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 KXX79493.1 - 2.6e-06 27.2 13.2 2.8e-05 23.9 4.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXX79493.1 - 4.8e-06 26.3 12.9 3.4e-05 23.6 4.8 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXX79493.1 - 0.00051 20.0 0.8 0.00051 20.0 0.8 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXX79493.1 - 0.0021 18.1 0.8 0.0021 18.1 0.8 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KXX79493.1 - 0.012 15.7 1.2 0.012 15.7 1.2 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_4 PF14570.6 KXX79493.1 - 0.098 12.5 12.0 1.3 8.9 3.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KXX79493.1 - 0.13 12.3 9.6 0.22 11.6 1.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 KXX79493.1 - 0.14 12.0 12.4 1.3 8.9 3.9 2.8 2 1 0 2 2 2 0 PHD-finger SPX PF03105.19 KXX79493.1 - 0.16 11.8 2.3 0.19 11.6 2.3 1.2 1 0 0 1 1 1 0 SPX domain zinc-ribbons_6 PF07191.12 KXX79493.1 - 0.3 11.1 11.3 0.44 10.6 1.8 2.4 2 0 0 2 2 2 0 zinc-ribbons Suf PF05843.14 KXX79493.1 - 0.57 10.1 9.8 0.67 9.9 3.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Cytochrom_CIII PF02085.16 KXX79493.1 - 0.72 10.2 6.8 0.083 13.2 1.0 2.1 2 0 0 2 2 2 0 Class III cytochrome C family Zn_ribbon_17 PF17120.5 KXX79493.1 - 0.78 9.4 14.4 0.055 13.1 4.5 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-TFIIB PF13453.6 KXX79493.1 - 0.79 9.1 5.5 28 4.1 0.1 3.6 3 0 0 3 3 3 0 Transcription factor zinc-finger Prok-RING_1 PF14446.6 KXX79493.1 - 1 9.4 10.9 12 6.0 0.2 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Anti-TRAP PF15777.5 KXX79493.1 - 2.3 8.2 10.1 0.81 9.7 0.4 3.0 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Rad50_zn_hook PF04423.14 KXX79493.1 - 4.3 7.3 7.7 0.34 10.8 0.3 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zinc_ribbon_9 PF14369.6 KXX79493.1 - 5.2 7.4 7.9 2.7 8.3 3.6 2.3 2 0 0 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KXX79493.1 - 5.3 7.3 7.9 1.6 8.9 1.3 2.7 2 0 0 2 2 2 0 Zinc ribbon domain WW PF00397.26 KXX79494.1 - 0.00044 20.3 0.8 0.00044 20.3 0.8 2.2 2 0 0 2 2 2 1 WW domain UBM PF14377.6 KXX79494.1 - 0.049 13.1 0.3 0.14 11.6 0.3 1.8 1 0 0 1 1 1 0 Ubiquitin binding region zf-CSL PF05207.13 KXX79496.1 - 0.052 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 CSL zinc finger Amidohydro_3 PF07969.11 KXX79498.1 - 2.1e-45 156.1 0.5 3.5e-45 155.4 0.5 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXX79498.1 - 0.0042 16.5 0.0 0.047 13.0 0.1 2.2 2 0 0 2 2 2 1 Amidohydrolase family dCMP_cyt_deam_1 PF00383.23 KXX79499.1 - 0.0001 22.1 0.1 0.00014 21.7 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 3D PF06725.11 KXX79499.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 3D domain LmjF365940-deam PF14421.6 KXX79499.1 - 0.13 11.8 0.6 8.6 5.9 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases MFS_1 PF07690.16 KXX79500.1 - 2.5e-25 89.1 28.6 1.8e-21 76.5 6.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3040 PF11239.8 KXX79500.1 - 2.6 8.4 6.2 3.3 8.0 2.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) NDUF_B7 PF05676.13 KXX79501.1 - 1.3e-29 101.7 7.3 1.5e-29 101.5 7.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KXX79501.1 - 0.14 12.1 3.9 0.088 12.8 2.0 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_S28 PF05577.12 KXX79502.1 - 2.4e-47 161.7 0.0 3.5e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 KXX79502.1 - 0.24 10.5 0.0 0.35 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Fungal_trans PF04082.18 KXX79504.1 - 1.9e-13 50.1 0.0 2.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX79504.1 - 3.4e-08 33.5 11.4 5.3e-08 32.9 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KXX79505.1 - 1.2e-20 73.9 0.2 1.1e-13 51.5 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX79505.1 - 1.2e-19 70.4 0.1 4.6e-10 39.8 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX79505.1 - 5.1e-17 61.5 3.1 0.00021 21.6 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KXX79505.1 - 1.2e-15 56.0 0.6 0.00088 19.6 0.1 4.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXX79505.1 - 5.1e-15 55.4 0.2 9e-07 29.1 0.0 2.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) FAD_binding_3 PF01494.19 KXX79506.1 - 3.8e-15 56.0 0.1 5.7e-07 29.1 0.2 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXX79506.1 - 1.1e-09 38.0 0.3 1.4e-08 34.3 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX79506.1 - 3.4e-09 36.8 0.4 9.5e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX79506.1 - 5.7e-08 32.3 0.9 9.1e-08 31.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXX79506.1 - 3.4e-07 30.4 0.1 9.3e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXX79506.1 - 4.6e-07 28.9 0.3 5e-06 25.5 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXX79506.1 - 3e-06 26.6 0.0 4.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXX79506.1 - 1.4e-05 24.7 0.0 2.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX79506.1 - 1.4e-05 25.5 0.4 0.00026 21.5 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXX79506.1 - 0.00061 18.8 0.2 0.71 8.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KXX79506.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXX79506.1 - 0.0023 17.0 0.4 0.0086 15.2 0.4 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXX79506.1 - 0.0025 17.1 0.1 0.005 16.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXX79506.1 - 0.02 14.2 0.0 0.31 10.3 0.0 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXX79506.1 - 0.054 13.5 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 KXX79506.1 - 0.08 11.3 0.1 0.11 10.8 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 KXX79506.1 - 0.11 11.7 0.4 0.21 10.8 0.1 1.5 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 KXX79506.1 - 0.15 11.9 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXX79506.1 - 0.19 11.3 0.1 0.38 10.3 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Response_reg PF00072.24 KXX79508.1 - 4.7e-27 94.4 0.2 1.4e-26 92.9 0.2 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KXX79508.1 - 1.5e-26 93.1 0.0 3.3e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXX79508.1 - 8.5e-17 61.0 0.1 1.7e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KXX79508.1 - 4.7e-11 42.9 0.0 1.2e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KXX79508.1 - 4.9e-07 29.7 0.0 1.5e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KXX79508.1 - 1e-05 25.7 0.0 0.0073 16.6 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KXX79508.1 - 0.045 14.0 0.3 0.13 12.6 0.3 1.8 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 KXX79508.1 - 0.059 13.4 0.0 6.4 6.9 0.0 3.0 3 0 0 3 3 3 0 PAS domain TFIIIC_sub6 PF10419.9 KXX79510.1 - 2.1e-26 91.6 0.0 3.8e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 KXX79511.1 - 3.3e-10 38.9 0.2 6.5e-10 37.9 0.2 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 KXX79511.1 - 0.022 13.4 2.1 0.024 13.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1302) DUF1996 PF09362.10 KXX79512.1 - 1.9e-79 267.0 0.4 2.4e-79 266.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_11 PF00457.17 KXX79513.1 - 1e-80 269.6 18.1 1.6e-80 268.9 18.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KXX79513.1 - 2.2e-12 46.7 18.6 2.2e-12 46.7 18.6 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain DUF4450 PF14614.6 KXX79513.1 - 0.062 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Toxin_7 PF05980.12 KXX79513.1 - 0.52 10.6 8.8 0.94 9.8 8.8 1.5 1 0 0 1 1 1 0 Toxin 7 ODC_AZ PF02100.17 KXX79514.1 - 1.3e-41 141.2 0.1 1.8e-41 140.7 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF1823 PF08853.11 KXX79514.1 - 0.033 14.4 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) TIR_2 PF13676.6 KXX79514.1 - 0.16 12.6 0.0 0.44 11.2 0.0 1.7 2 0 0 2 2 2 0 TIR domain His_biosynth PF00977.21 KXX79515.1 - 2.5e-49 167.8 0.1 8.4e-49 166.1 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KXX79515.1 - 3.8e-18 65.9 0.0 6.1e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KXX79515.1 - 1.7e-08 34.5 0.0 6.8e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXX79515.1 - 1.8e-06 27.7 0.0 4.9e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 KXX79515.1 - 0.036 13.1 0.0 0.084 12.0 0.0 1.5 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 KXX79515.1 - 0.056 13.2 0.0 0.86 9.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 MIF PF01187.18 KXX79516.1 - 2.1e-07 31.3 0.0 2.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.12 KXX79517.1 - 3e-70 236.2 0.1 3.8e-70 235.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KXX79517.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 KXX79517.1 - 0.031 14.6 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 KXX79517.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXX79517.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase STAT1_TAZ2bind PF12162.8 KXX79518.1 - 0.18 11.4 0.3 0.18 11.4 0.3 1.7 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain Tim17 PF02466.19 KXX79519.1 - 3.1e-27 95.1 1.9 4.5e-27 94.6 1.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Endonuclease_5 PF04493.14 KXX79519.1 - 0.03 14.0 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Endonuclease V XhlA PF10779.9 KXX79520.1 - 9.7e-06 25.7 1.1 0.017 15.3 0.2 2.4 1 1 1 2 2 2 2 Haemolysin XhlA CLZ PF16526.5 KXX79520.1 - 1.5e-05 25.3 1.2 0.008 16.5 0.2 2.5 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSBP1 PF06825.12 KXX79520.1 - 2.9e-05 23.8 1.2 0.00013 21.8 1.2 2.2 1 1 0 1 1 1 1 Heat shock factor binding protein 1 EzrA PF06160.12 KXX79520.1 - 0.00038 18.8 0.1 0.00049 18.4 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA UPF0184 PF03670.13 KXX79520.1 - 0.0016 18.8 0.4 0.015 15.6 0.4 2.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) DUF4164 PF13747.6 KXX79520.1 - 0.0019 18.4 1.4 0.91 9.8 0.6 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4164) MscS_porin PF12795.7 KXX79520.1 - 0.0056 16.3 0.1 0.007 15.9 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Vac_Fusion PF02346.16 KXX79520.1 - 0.0058 16.2 1.5 0.062 12.9 1.5 2.5 2 1 0 2 2 1 1 Chordopoxvirus multifunctional envelope protein A27 ABC_tran_CTD PF16326.5 KXX79520.1 - 0.0062 16.8 0.1 1.2 9.4 0.1 2.4 1 1 0 2 2 2 1 ABC transporter C-terminal domain NPV_P10 PF05531.12 KXX79520.1 - 0.0077 16.7 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXX79520.1 - 0.0085 16.5 0.3 0.097 13.1 0.0 2.1 1 1 1 2 2 2 2 Flagella accessory protein C (FlaC) Osmo_CC PF08946.10 KXX79520.1 - 0.021 15.0 3.5 0.042 14.1 0.3 2.6 2 1 1 3 3 2 0 Osmosensory transporter coiled coil Prefoldin_2 PF01920.20 KXX79520.1 - 0.022 14.7 0.1 2.7 8.0 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit YvrJ PF12841.7 KXX79520.1 - 0.023 14.2 3.9 4.8 6.8 0.1 3.4 3 1 0 3 3 3 0 YvrJ protein family Nsp1_C PF05064.13 KXX79520.1 - 0.023 14.5 0.1 0.098 12.5 0.1 2.0 1 1 0 1 1 1 0 Nsp1-like C-terminal region Baculo_PEP_C PF04513.12 KXX79520.1 - 0.024 14.7 0.1 0.049 13.7 0.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.6 KXX79520.1 - 0.026 14.6 0.2 2 8.5 0.1 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term COG6 PF06419.11 KXX79520.1 - 0.032 12.5 0.1 0.043 12.0 0.1 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Tropomyosin PF00261.20 KXX79520.1 - 0.035 13.5 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin TRPM_tetra PF16519.5 KXX79520.1 - 0.035 14.2 0.4 5.2 7.3 0.1 2.5 1 1 1 2 2 2 0 Tetramerisation domain of TRPM Cluap1 PF10234.9 KXX79520.1 - 0.041 13.3 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 COG5 PF10392.9 KXX79520.1 - 0.041 14.1 0.1 11 6.2 0.0 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Allexi_40kDa PF05549.11 KXX79520.1 - 0.046 13.2 0.2 0.065 12.7 0.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4455 PF14643.6 KXX79520.1 - 0.051 12.2 0.2 0.057 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF2730 PF10805.8 KXX79520.1 - 0.054 13.6 0.2 0.21 11.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) LegC3_N PF18654.1 KXX79520.1 - 0.054 12.7 0.2 0.071 12.3 0.2 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Snapin_Pallidin PF14712.6 KXX79520.1 - 0.064 13.7 0.0 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin ADIP PF11559.8 KXX79520.1 - 0.065 13.3 0.5 0.23 11.5 0.4 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Spc19 PF08287.11 KXX79520.1 - 0.066 13.1 0.4 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Spc19 Laminin_II PF06009.12 KXX79520.1 - 0.075 13.1 0.1 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 Laminin Domain II Nup54 PF13874.6 KXX79520.1 - 0.088 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RmuC PF02646.16 KXX79520.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 RmuC family DUF16 PF01519.16 KXX79520.1 - 0.13 12.8 0.7 13 6.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spc24 PF08286.11 KXX79520.1 - 0.13 12.5 0.6 1.6 9.0 0.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF812 PF05667.11 KXX79520.1 - 0.16 10.8 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 KXX79520.1 - 0.16 11.5 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit vATP-synt_E PF01991.18 KXX79520.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit MtrG PF04210.13 KXX79520.1 - 0.2 11.5 0.1 4.9 7.1 0.0 2.3 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G CCDC53 PF10152.9 KXX79520.1 - 0.21 12.0 0.4 4.7 7.6 0.4 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex TMPIT PF07851.13 KXX79520.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.3 1 1 0 1 1 1 0 TMPIT-like protein Sugarporin_N PF11471.8 KXX79520.1 - 0.25 11.3 1.6 4.8 7.2 0.4 2.4 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension HalX PF08663.10 KXX79520.1 - 0.38 11.1 5.0 7.6 6.9 4.4 2.4 1 1 1 2 2 2 0 HalX domain SlyX PF04102.12 KXX79520.1 - 0.41 11.3 2.4 26 5.5 0.3 2.4 1 1 1 2 2 2 0 SlyX Trimer_CC PF08954.11 KXX79520.1 - 1.4 8.5 7.2 5.7 6.6 0.1 3.1 2 1 0 2 2 2 0 Trimerisation motif DUF2428 PF10350.9 KXX79522.1 - 1.1e-58 198.7 0.1 2.6e-58 197.5 0.1 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KXX79522.1 - 6.6e-06 25.9 11.3 8.9 6.9 0.0 7.4 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 KXX79522.1 - 0.00017 21.9 0.6 0.23 11.8 0.0 4.2 5 0 0 5 5 5 2 HEAT repeats Polyoma_agno PF01736.16 KXX79522.1 - 0.11 12.2 0.8 22 4.9 0.0 3.6 3 0 0 3 3 3 0 Polyomavirus agnoprotein YEATS PF03366.16 KXX79523.1 - 1.5e-29 101.8 0.3 2.3e-29 101.2 0.3 1.3 1 0 0 1 1 1 1 YEATS family Med21 PF11221.8 KXX79523.1 - 0.38 11.0 3.6 0.75 10.0 3.6 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Ins_P5_2-kin PF06090.12 KXX79525.1 - 1.9e-39 136.1 0.0 6.1e-39 134.4 0.0 1.7 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.18 KXX79526.1 - 7.9e-39 133.9 6.5 7.9e-39 133.9 6.5 2.9 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 KXX79526.1 - 0.001 18.1 7.2 0.001 18.1 7.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Catalase PF00199.19 KXX79527.1 - 2e-164 547.3 0.0 2.5e-164 547.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KXX79527.1 - 1.3e-46 158.0 0.0 2.1e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KXX79527.1 - 1.4e-20 73.2 0.1 2.8e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Haspin_kinase PF12330.8 KXX79528.1 - 2.1e-33 115.8 0.0 7.9e-33 113.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXX79528.1 - 0.041 13.8 0.4 0.1 12.5 0.4 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1682 PF07946.14 KXX79529.1 - 1.2e-111 373.0 1.8 1.4e-111 372.8 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) AnkUBD PF18418.1 KXX79529.1 - 0.0045 17.1 0.0 0.099 12.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin ubiquitin-binding domain Big_3 PF07523.12 KXX79529.1 - 0.015 15.6 0.1 3 8.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) TAF4 PF05236.14 KXX79529.1 - 0.32 10.7 12.2 0.47 10.2 12.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Thiamine_BP PF01910.17 KXX79530.1 - 1.4e-31 108.2 0.3 1.6e-31 108.0 0.3 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 KXX79530.1 - 7.2e-05 22.7 0.0 9.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Acid_PPase PF12689.7 KXX79530.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.4 1 1 0 1 1 1 0 Acid Phosphatase DUF2834 PF11196.8 KXX79531.1 - 1.3e-06 28.7 0.6 0.007 16.7 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Arf PF00025.21 KXX79532.1 - 9.9e-40 135.8 0.0 1.4e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXX79532.1 - 7.4e-16 58.2 0.0 1.8e-10 40.6 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXX79532.1 - 9e-09 35.0 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXX79532.1 - 1.8e-08 34.6 0.0 3.5e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXX79532.1 - 7.6e-07 28.9 0.0 1.8e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 KXX79532.1 - 8.8e-07 28.5 0.0 1.9e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXX79532.1 - 0.0013 18.4 0.0 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX79532.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_L29e PF01779.17 KXX79533.1 - 3.2e-23 81.8 9.2 4.7e-23 81.2 9.2 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family SAM_2 PF07647.17 KXX79534.1 - 1.3e-09 38.0 0.1 2.5e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXX79534.1 - 7.2e-05 23.2 0.3 0.00015 22.2 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KXX79534.1 - 0.0073 16.4 0.4 0.019 15.0 0.3 1.7 2 0 0 2 2 2 1 IGR protein motif ALIX_LYPXL_bnd PF13949.6 KXX79534.1 - 0.03 13.6 0.5 0.053 12.8 0.5 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4508 PF14969.6 KXX79534.1 - 0.1 12.9 0.1 0.28 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF1031 PF06275.11 KXX79534.1 - 0.23 11.7 0.2 0.53 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Peptidase_C2 PF00648.21 KXX79535.1 - 1.3e-34 119.6 0.0 2e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Mito_carr PF00153.27 KXX79536.1 - 4.4e-56 186.8 0.8 4.4e-19 68.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltr_RsmB-F PF01189.17 KXX79537.1 - 3.7e-19 69.1 0.0 2.2e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Dicty_REP PF05086.12 KXX79537.1 - 4.8 5.0 4.3 6.8 4.5 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EBP PF05241.12 KXX79538.1 - 1.2e-52 178.0 3.7 1.5e-52 177.6 3.7 1.1 1 0 0 1 1 1 1 Emopamil binding protein P33MONOX PF15302.6 KXX79538.1 - 0.23 11.2 0.4 0.44 10.2 0.4 1.3 1 0 0 1 1 1 0 P33 mono-oxygenase TPR_2 PF07719.17 KXX79539.1 - 3.1e-09 36.2 19.8 0.3 11.3 0.1 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX79539.1 - 3.7e-09 36.0 14.0 2 8.4 0.3 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX79539.1 - 1.1e-07 31.5 10.8 4.8 7.7 0.2 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX79539.1 - 2.7e-05 24.6 12.1 1.5 9.4 0.1 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX79539.1 - 7.2e-05 23.3 22.2 0.34 11.8 0.1 9.6 9 3 2 11 11 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXX79539.1 - 0.00011 21.8 6.8 0.043 13.5 0.3 5.5 4 1 1 5 5 5 1 TPR repeat TPR_17 PF13431.6 KXX79539.1 - 0.00027 21.1 2.4 48 4.6 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXX79539.1 - 0.00028 20.7 13.0 4.9 7.4 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KXX79539.1 - 0.0055 17.0 10.2 0.45 10.9 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX79539.1 - 0.013 16.1 26.4 0.16 12.6 0.0 7.2 7 2 2 9 9 9 0 Tetratricopeptide repeat ELYS PF13934.6 KXX79539.1 - 0.068 13.1 0.2 6.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore complex assembly TPR_6 PF13174.6 KXX79539.1 - 0.64 10.8 11.6 24 5.8 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXX79539.1 - 4.1 7.8 25.5 1.1 9.6 0.0 7.5 7 2 2 9 9 9 0 Tetratricopeptide repeat DUF1996 PF09362.10 KXX79540.1 - 1.5e-59 201.8 0.7 1.8e-59 201.6 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) WSC PF01822.19 KXX79540.1 - 1.5e-18 66.8 13.4 3.2e-18 65.7 10.8 2.4 2 0 0 2 2 2 1 WSC domain Cwf_Cwc_15 PF04889.12 KXX79541.1 - 2e-89 299.5 18.1 2.3e-89 299.4 18.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SART-1 PF03343.13 KXX79541.1 - 0.00021 20.0 13.7 0.00025 19.8 13.7 1.1 1 0 0 1 1 1 1 SART-1 family YL1 PF05764.13 KXX79541.1 - 0.011 15.9 21.7 0.018 15.2 21.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 KXX79541.1 - 0.18 11.2 22.3 0.22 10.9 22.3 1.1 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 KXX79541.1 - 0.56 9.5 13.6 0.72 9.2 13.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3381 PF11861.8 KXX79541.1 - 0.63 9.8 16.7 1.3 8.8 16.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 KXX79541.1 - 1.2 7.3 20.2 1.4 7.1 20.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 KXX79541.1 - 2.6 6.8 9.9 3.1 6.5 9.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.12 KXX79541.1 - 3.4 5.8 23.9 3.9 5.6 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 KXX79541.1 - 4.2 5.4 5.4 4.7 5.2 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNase_PH PF01138.21 KXX79542.1 - 1.3e-21 77.5 0.0 2.2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXX79542.1 - 5.2e-08 32.8 0.0 1.4e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Disaggr_repeat PF06848.11 KXX79542.1 - 0.21 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Disaggregatase related repeat CoaE PF01121.20 KXX79544.1 - 1.2e-42 145.6 0.0 5.4e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 KXX79544.1 - 0.0095 16.1 0.0 0.11 12.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXX79544.1 - 0.018 15.6 0.2 0.3 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CcmH PF03918.14 KXX79544.1 - 0.028 13.7 0.9 0.049 12.9 0.9 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein FixP_N PF14715.6 KXX79544.1 - 0.14 11.9 3.1 0.26 11.1 3.1 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP NAD_binding_10 PF13460.6 KXX79545.1 - 7.3e-06 26.0 0.0 0.00032 20.7 0.0 2.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX79545.1 - 1.1e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX79545.1 - 0.0022 17.0 0.0 0.0047 16.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXX79545.1 - 0.012 14.8 0.0 0.084 12.0 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 KXX79545.1 - 0.035 13.2 0.0 0.27 10.3 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain SYF2 PF08231.12 KXX79546.1 - 1.3e-53 181.6 11.7 1.3e-53 181.6 11.7 1.8 2 0 0 2 2 2 1 SYF2 splicing factor Bravo_FIGEY PF13882.6 KXX79546.1 - 0.036 15.4 1.4 0.036 15.4 1.4 3.6 2 2 1 3 3 3 0 Bravo-like intracellular region ARD PF03079.14 KXX79546.1 - 9.3 6.4 8.6 0.62 10.2 0.2 2.8 1 1 3 4 4 4 0 ARD/ARD' family HEAT PF02985.22 KXX79547.1 - 0.00041 20.3 3.5 0.043 14.1 0.4 4.9 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KXX79547.1 - 0.004 17.5 5.9 1.3 9.4 0.1 5.0 5 0 0 5 5 5 1 HEAT repeats FANCI_S2 PF14676.6 KXX79547.1 - 0.041 14.2 0.2 2.4 8.5 0.1 3.2 3 0 0 3 3 3 0 FANCI solenoid 2 TraY PF05509.11 KXX79547.1 - 0.066 13.3 0.4 0.16 12.0 0.4 1.6 1 0 0 1 1 1 0 TraY domain DUF4507 PF14964.6 KXX79547.1 - 0.089 11.7 0.1 0.45 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4507) HEAT_EZ PF13513.6 KXX79547.1 - 0.14 12.7 2.6 2.4 8.8 1.4 3.6 3 0 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.25 KXX79548.1 - 1.1e-38 133.2 0.0 1.5e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79548.1 - 2.7e-28 99.0 0.0 3.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXX79548.1 - 0.0045 17.0 0.1 1.3 8.9 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF3439 PF11921.8 KXX79548.1 - 0.72 9.8 4.9 0.43 10.6 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1749 PF08538.10 KXX79549.1 - 1.3e-87 293.7 0.0 1.5e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KXX79549.1 - 8.4e-06 26.5 0.1 1.3e-05 26.0 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX79549.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 KXX79549.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.16 KXX79549.1 - 0.13 12.1 0.0 5.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXX79549.1 - 0.17 11.1 0.0 0.67 9.2 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 p450 PF00067.22 KXX79551.1 - 1.9e-45 155.5 0.0 3.5e-45 154.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Alpha-amylase PF00128.24 KXX79551.1 - 0.13 11.8 0.2 0.2 11.2 0.2 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain eIF-5_eIF-2B PF01873.17 KXX79552.1 - 2e-38 130.9 0.0 4e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KXX79552.1 - 1.1e-22 80.0 0.4 1.1e-22 80.0 0.4 2.3 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4519 PF15012.6 KXX79552.1 - 3.3 8.0 5.1 11 6.3 5.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF3328 PF11807.8 KXX79553.1 - 1.8e-21 76.9 0.6 8.3e-21 74.8 0.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SUZ-C PF12901.7 KXX79556.1 - 0.051 13.6 0.6 16 5.6 0.1 2.7 2 0 0 2 2 2 0 SUZ-C motif DUF134 PF02001.16 KXX79557.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF134 MRP-S31 PF15433.6 KXX79559.1 - 0.0015 18.3 1.0 0.0018 18.0 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 APG6_N PF17675.1 KXX79559.1 - 0.0057 17.2 5.9 0.012 16.2 5.9 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region Macoilin PF09726.9 KXX79559.1 - 0.017 13.7 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF3584 PF12128.8 KXX79559.1 - 0.038 11.5 6.6 0.048 11.2 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BssS PF13991.6 KXX79559.1 - 0.074 13.1 0.2 0.074 13.1 0.2 2.2 3 0 0 3 3 3 0 BssS protein family Cep57_CLD_2 PF14197.6 KXX79559.1 - 0.11 12.6 16.2 0.92 9.6 1.0 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Prp19 PF08606.11 KXX79559.1 - 1.3 9.1 7.8 0.13 12.3 1.9 2.3 2 0 0 2 2 2 0 Prp19/Pso4-like TEX13 PF15186.6 KXX79559.1 - 2.2 8.0 10.3 0.33 10.6 1.8 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF1635 PF07795.11 KXX79559.1 - 3.5 7.4 8.9 4 7.2 6.5 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) BNR_2 PF13088.6 KXX79560.1 - 0.0017 17.7 0.7 0.093 12.0 0.1 2.1 1 1 0 2 2 2 2 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KXX79560.1 - 0.093 11.5 0.0 3.4 6.4 0.0 2.0 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, Glyco_hydro_3_C PF01915.22 KXX79561.1 - 2.9e-35 122.1 0.0 4.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX79561.1 - 7.8e-33 114.2 0.0 1.1e-32 113.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX79561.1 - 5.2e-06 26.5 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4232 PF14016.6 KXX79561.1 - 0.36 11.0 1.8 0.62 10.2 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4232) Ank_2 PF12796.7 KXX79562.1 - 0.00037 21.0 0.0 0.00077 20.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Acetyltransf_7 PF13508.7 KXX79562.1 - 0.00046 20.5 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX79562.1 - 0.00074 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ank_4 PF13637.6 KXX79562.1 - 0.0012 19.4 0.0 0.0041 17.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) FR47 PF08445.10 KXX79562.1 - 0.0019 18.1 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KXX79562.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Ank_3 PF13606.6 KXX79562.1 - 0.0027 18.0 0.0 0.0095 16.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 KXX79562.1 - 0.0094 16.4 0.2 0.041 14.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KXX79562.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Acetyltransf_10 PF13673.7 KXX79562.1 - 0.021 14.8 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXX79562.1 - 0.1 12.1 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Putative acetyl-transferase Bestrophin PF01062.21 KXX79565.1 - 1.1 8.5 5.4 2.7 7.3 0.1 2.4 1 1 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Microvir_lysis PF04517.12 KXX79566.1 - 0.19 11.7 1.3 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus Pkinase PF00069.25 KXX79567.1 - 1.4e-17 64.0 0.0 1.4e-10 41.0 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79567.1 - 1.8e-05 24.2 0.0 0.15 11.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Esterase_phd PF10503.9 KXX79568.1 - 5.8e-07 29.2 0.1 2e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KXX79568.1 - 5e-06 26.5 0.0 7.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXX79568.1 - 1.4e-05 24.6 0.1 2.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXX79568.1 - 1.9e-05 24.5 0.1 5.5e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KXX79568.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 KXX79568.1 - 0.068 12.7 0.1 0.18 11.3 0.0 1.6 1 1 1 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXX79568.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cnd1_N PF12922.7 KXX79569.1 - 1.6e-63 213.5 0.1 1.6e-63 213.5 0.1 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KXX79569.1 - 1.3e-50 171.6 0.5 8e-46 156.0 0.0 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXX79569.1 - 7.9e-10 38.1 8.7 0.049 13.9 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 KXX79569.1 - 7e-09 36.0 6.7 8.3e-05 22.9 0.2 5.4 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KXX79569.1 - 3.5e-05 24.2 5.4 0.15 12.6 0.4 5.2 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 KXX79569.1 - 4.2e-05 23.7 0.0 0.32 11.2 0.0 3.3 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KXX79569.1 - 0.00044 18.9 3.0 0.033 12.7 0.2 3.6 3 0 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 KXX79569.1 - 0.00047 19.4 0.5 0.00047 19.4 0.5 3.6 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain TMA7 PF09072.10 KXX79569.1 - 0.65 10.9 9.5 0.3 12.0 2.2 3.0 2 0 0 2 2 2 0 Translation machinery associated TMA7 Pkinase PF00069.25 KXX79570.1 - 2.7e-41 141.7 0.0 6.5e-38 130.6 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79570.1 - 2.7e-13 49.8 0.0 1.4e-07 31.1 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KXX79570.1 - 0.00066 19.7 0.1 0.03 14.3 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXX79570.1 - 0.017 13.9 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXX79570.1 - 0.019 14.3 0.0 5.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KXX79570.1 - 0.021 14.4 0.0 0.38 10.4 0.0 2.6 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Helicase_C_2 PF13307.6 KXX79571.1 - 5.4e-57 192.7 0.0 1.6e-56 191.1 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXX79571.1 - 1e-47 162.0 0.0 2.1e-47 161.0 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KXX79571.1 - 0.0049 16.9 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXX79571.1 - 0.11 12.7 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain HET PF06985.11 KXX79572.1 - 2.1e-22 80.0 0.0 3.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXX79573.1 - 1e-21 77.8 0.0 2.3e-21 76.7 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GRIM-19 PF06212.12 KXX79574.1 - 5.6e-22 78.1 0.0 1.3e-21 76.9 0.0 1.6 1 1 0 1 1 1 1 GRIM-19 protein NIF PF03031.18 KXX79575.1 - 1.9e-26 92.7 0.0 4.2e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KXX79575.1 - 0.00013 21.8 0.0 0.00075 19.4 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KXX79575.1 - 0.0074 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.22 KXX79575.1 - 0.022 14.6 0.0 8.4 6.3 0.0 2.9 1 1 1 2 2 2 0 Biotin-requiring enzyme DUF3606 PF12244.8 KXX79575.1 - 0.078 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) GRAM PF02893.20 KXX79576.1 - 1.8e-31 108.4 0.3 2.8e-19 69.1 0.0 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KXX79576.1 - 2.9e-28 98.6 0.0 6.2e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KXX79576.1 - 6.6e-11 42.7 0.1 1.6e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KXX79576.1 - 0.00018 21.7 0.2 0.0011 19.1 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 KXX79576.1 - 0.00054 18.9 0.0 0.0016 17.3 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.6 KXX79576.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KXX79576.1 - 0.0059 17.0 1.4 0.074 13.5 1.4 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KXX79576.1 - 0.18 12.2 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region E1-E2_ATPase PF00122.20 KXX79577.1 - 2.2e-50 170.7 3.6 5.9e-50 169.3 3.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXX79577.1 - 1.7e-26 93.9 0.1 3.4e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXX79577.1 - 4.7e-06 27.0 1.3 2.6e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KXX79577.1 - 0.0046 16.7 0.2 0.058 13.1 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SCAMP PF04144.13 KXX79577.1 - 4.6 7.5 7.0 0.89 9.8 2.0 2.2 2 0 0 2 2 2 0 SCAMP family SdpI PF13630.6 KXX79579.1 - 0.038 14.1 0.1 0.038 14.1 0.1 3.0 2 1 1 3 3 3 0 SdpI/YhfL protein family DUF1772 PF08592.11 KXX79579.1 - 0.053 13.8 4.5 2.8 8.2 0.4 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Ferric_reduct PF01794.19 KXX79579.1 - 1.2 9.3 11.2 1.1 9.3 9.3 2.0 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Glyco_hydro2_C5 PF18565.1 KXX79581.1 - 4.3e-33 113.2 0.1 1e-32 112.0 0.1 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 KXX79581.1 - 6.6e-25 87.8 0.0 2.3e-24 86.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 KXX79581.1 - 3.7e-24 84.4 0.2 1.2e-23 82.8 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 KXX79581.1 - 2.8e-19 69.6 0.1 7.9e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KXX79581.1 - 5.5e-13 49.5 0.0 1.5e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KXX79581.1 - 0.00012 22.7 0.0 0.0011 19.6 0.0 2.7 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 KXX79581.1 - 0.00094 19.4 0.2 0.00094 19.4 0.2 2.7 3 0 0 3 3 3 1 Invasin, domain 3 Big_1 PF02369.16 KXX79581.1 - 0.0042 17.1 2.7 0.018 15.0 2.7 2.1 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) DUF3632 PF12311.8 KXX79582.1 - 1.1e-24 87.8 4.7 1.6e-24 87.3 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.11 KXX79583.1 - 1.1e-21 77.7 0.1 1.8e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rad4 PF03835.15 KXX79585.1 - 6.4e-11 42.1 0.7 1.6e-10 40.8 0.7 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KXX79585.1 - 8.5e-08 32.6 1.2 1.8e-07 31.6 1.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 KXX79585.1 - 0.23 11.2 4.5 6.8 6.5 0.3 2.5 1 1 1 2 2 2 0 Cold-inducible protein YdjO DUF846 PF05832.12 KXX79586.1 - 4.3e-45 153.2 8.9 5.2e-45 152.9 8.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5504 PF17608.2 KXX79586.1 - 0.019 15.1 0.8 0.019 15.1 0.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5504) TctB PF07331.11 KXX79586.1 - 0.43 10.8 13.2 2.5 8.4 4.3 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family TMEM220 PF15071.6 KXX79586.1 - 7.4 7.4 7.8 1.6 9.5 3.2 1.9 1 1 1 2 2 2 0 Transmembrane family 220, helix HpcH_HpaI PF03328.14 KXX79587.1 - 3e-41 141.0 0.0 4.9e-41 140.3 0.0 1.3 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KXX79587.1 - 7.8e-15 54.8 0.0 1.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Hep_59 PF07052.11 KXX79588.1 - 4.4e-20 72.4 1.5 4.4e-20 72.4 1.5 2.8 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 FlgT_M PF16539.5 KXX79588.1 - 0.0021 18.2 3.0 0.0021 18.2 3.0 2.1 3 0 0 3 3 3 1 Flagellar assembly protein T, middle domain DMAP_binding PF06464.11 KXX79588.1 - 0.039 14.8 0.3 0.039 14.8 0.3 3.1 3 0 0 3 3 3 0 DMAP1-binding Domain SKG6 PF08693.10 KXX79589.1 - 0.00049 19.5 3.0 0.001 18.5 3.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 KXX79589.1 - 0.027 14.4 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain WD40 PF00400.32 KXX79590.1 - 7.2e-15 55.1 11.1 0.0078 17.0 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79590.1 - 4.6e-07 30.0 0.3 0.002 18.4 0.2 4.2 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX79590.1 - 3.3e-06 26.0 4.1 3.7e-05 22.6 2.5 2.9 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXX79590.1 - 0.0028 16.5 0.1 4.4 5.9 0.0 3.1 1 1 1 2 2 2 2 Nup133 N terminal like Ribosomal_L6 PF00347.23 KXX79591.1 - 1.8e-25 89.4 7.1 2.9e-12 47.1 0.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 TMEM51 PF15345.6 KXX79592.1 - 0.0092 15.8 0.3 0.31 10.8 0.0 2.2 2 0 0 2 2 2 1 Transmembrane protein 51 Phage_holin_3_6 PF07332.11 KXX79592.1 - 0.026 14.6 2.7 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zf-TRM13_CCCH PF11722.8 KXX79592.1 - 0.086 12.6 4.1 0.23 11.2 4.1 1.8 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein DUF4690 PF15756.5 KXX79592.1 - 0.22 12.2 2.9 0.56 10.9 2.9 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF726 PF05277.12 KXX79593.1 - 6.1e-126 420.0 1.9 8.6e-126 419.5 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Dicty_REP PF05086.12 KXX79594.1 - 4.2 5.2 5.0 6.4 4.6 5.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sld5 PF05916.11 KXX79595.1 - 3.4e-12 46.8 0.0 4.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 KXX79595.1 - 0.13 13.1 0.0 0.92 10.4 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein FliT Sulfate_transp PF00916.20 KXX79596.1 - 1.4e-52 178.8 14.5 2.3e-52 178.0 14.5 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KXX79596.1 - 5.4e-11 42.4 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KXX79596.1 - 3.7e-08 33.0 0.0 6.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain V-ATPase_H_N PF03224.14 KXX79597.1 - 4.5e-79 266.0 0.0 5.9e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KXX79597.1 - 6.2e-36 123.1 0.0 2.7e-35 121.0 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H ABC_tran_CTD PF16326.5 KXX79597.1 - 0.098 12.9 0.1 0.29 11.4 0.1 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain Fcf1 PF04900.12 KXX79598.1 - 8.7e-28 96.6 0.0 1.4e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 KXX79598.1 - 1.2 7.3 6.7 1.7 6.9 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIE PF07228.12 KXX79599.1 - 0.0021 18.0 0.0 0.0086 16.0 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PH PF00169.29 KXX79600.1 - 2.2e-07 31.3 0.3 8.1e-06 26.3 0.0 3.0 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 KXX79600.1 - 0.0015 18.9 0.0 0.023 15.1 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Pkinase PF00069.25 KXX79601.1 - 4.4e-63 213.1 0.0 9.8e-63 212.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79601.1 - 2.8e-29 102.2 0.0 7.6e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 KXX79601.1 - 2.2e-10 40.7 0.0 5e-07 30.0 0.0 2.8 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 KXX79601.1 - 0.0057 16.9 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KXX79601.1 - 0.012 15.5 0.0 2.2 8.1 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXX79601.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KXX79601.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family STT3 PF02516.14 KXX79603.1 - 1.5e-144 482.5 32.7 8e-140 467.0 30.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Ribosomal_L29 PF00831.23 KXX79604.1 - 9e-17 60.8 1.6 9e-17 60.8 1.6 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein AAA_2 PF07724.14 KXX79605.1 - 1.7e-44 151.9 0.0 2.1e-43 148.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXX79605.1 - 1.2e-35 121.6 2.0 1.2e-35 121.6 2.0 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KXX79605.1 - 1.9e-25 88.7 0.2 7.4e-25 86.8 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KXX79605.1 - 4e-19 69.4 0.0 4.1e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXX79605.1 - 1.9e-11 44.1 0.1 1e-08 35.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXX79605.1 - 1.5e-07 32.0 9.5 0.0035 17.7 0.6 4.3 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 KXX79605.1 - 1.4e-06 28.6 4.1 0.019 15.2 0.0 3.9 3 2 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KXX79605.1 - 1.6e-06 27.9 0.5 0.00053 19.7 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 KXX79605.1 - 1.5e-05 25.0 0.0 0.065 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KXX79605.1 - 3.9e-05 23.6 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 KXX79605.1 - 4.2e-05 23.6 8.2 0.3 10.9 0.0 4.4 4 1 1 5 5 5 2 ATPase domain predominantly from Archaea TniB PF05621.11 KXX79605.1 - 9.2e-05 21.9 0.1 0.016 14.7 0.0 3.4 3 1 0 3 3 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KXX79605.1 - 0.00045 20.0 0.3 0.55 9.9 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KXX79605.1 - 0.00057 19.5 0.0 0.82 9.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 KXX79605.1 - 0.00072 20.1 0.6 0.31 11.6 0.0 3.4 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 KXX79605.1 - 0.0011 18.9 1.6 1.3 8.9 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_18 PF13238.6 KXX79605.1 - 0.0023 18.5 2.8 0.3 11.6 0.0 3.6 4 0 0 4 4 2 1 AAA domain RNA_helicase PF00910.22 KXX79605.1 - 0.0035 17.7 0.0 1.2 9.6 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KXX79605.1 - 0.0058 16.8 0.0 3.1 8.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KXX79605.1 - 0.012 15.3 0.1 0.67 9.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KXX79605.1 - 0.013 15.2 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXX79605.1 - 0.018 15.3 2.2 11 6.3 0.0 4.0 3 1 1 4 4 3 0 AAA domain Roc PF08477.13 KXX79605.1 - 0.02 15.1 0.1 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 KXX79605.1 - 0.022 14.2 0.2 2.9 7.2 0.0 3.1 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KXX79605.1 - 0.024 14.6 0.1 6.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KXX79605.1 - 0.033 14.0 0.0 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Bacterial dnaA protein Zeta_toxin PF06414.12 KXX79605.1 - 0.039 13.2 0.0 2.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 KXX79605.1 - 0.04 13.1 0.4 1.8 7.7 0.3 3.2 3 2 0 3 3 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KXX79605.1 - 0.065 13.0 0.0 0.92 9.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KXX79605.1 - 0.075 12.9 0.1 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 KXX79605.1 - 0.1 12.9 1.0 2 8.7 0.0 3.1 3 1 0 3 3 2 0 AAA domain ERM PF00769.19 KXX79605.1 - 0.11 12.3 13.1 0.21 11.4 13.1 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_25 PF13481.6 KXX79605.1 - 0.12 11.9 0.9 1.6 8.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KXX79605.1 - 0.13 11.7 3.0 0.99 8.9 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain GBP_C PF02841.14 KXX79605.1 - 0.19 11.1 7.7 0.33 10.3 7.7 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Seryl_tRNA_N PF02403.22 KXX79605.1 - 0.2 11.9 13.5 0.35 11.1 11.4 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OEP PF02321.18 KXX79605.1 - 0.56 10.0 11.2 1.3 8.8 11.2 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein ADIP PF11559.8 KXX79605.1 - 1 9.5 13.2 2 8.5 13.2 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1640 PF07798.11 KXX79605.1 - 1.2 9.2 8.6 2.5 8.1 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GrpE PF01025.19 KXX79605.1 - 2.4 7.8 9.2 5.6 6.6 9.2 1.6 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 KXX79605.1 - 4.6 7.1 14.2 0.57 10.0 4.4 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4349 PF14257.6 KXX79605.1 - 7.9 5.9 14.1 4.1 6.8 1.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Arf PF00025.21 KXX79606.1 - 2.2e-78 261.7 0.2 2.6e-78 261.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXX79606.1 - 2.2e-14 53.7 0.0 3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXX79606.1 - 2.4e-13 49.9 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXX79606.1 - 3.6e-13 49.4 1.0 5e-09 35.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXX79606.1 - 8.6e-13 48.2 0.0 9.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXX79606.1 - 1.4e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXX79606.1 - 1e-05 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXX79606.1 - 0.0024 17.2 0.2 0.0071 15.7 0.1 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase EMP24_GP25L PF01105.24 KXX79607.1 - 2e-48 164.7 0.0 2.3e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1408 PF07193.11 KXX79607.1 - 0.07 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) SpoU_methylase PF00588.19 KXX79607.1 - 0.15 12.2 0.0 2.4 8.3 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family DUF3405 PF11885.8 KXX79608.1 - 8.6e-218 724.1 1.8 1.1e-217 723.8 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF2890 PF11081.8 KXX79608.1 - 0.1 12.7 1.4 0.24 11.5 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PBP1_TM PF14812.6 KXX79608.1 - 0.21 12.0 1.3 0.55 10.6 1.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5519 PF17648.1 KXX79609.1 - 0.09 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5519) ATP-synt_10 PF05176.14 KXX79610.1 - 7.2e-79 264.6 0.0 9e-79 264.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Rad51 PF08423.11 KXX79611.1 - 4.6e-128 425.8 0.0 5.6e-128 425.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KXX79611.1 - 4.9e-09 36.0 0.0 7.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KXX79611.1 - 2.4e-08 33.8 0.0 3.3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KXX79611.1 - 5.8e-06 26.8 1.3 1.6e-05 25.4 0.3 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KXX79611.1 - 1.5e-05 24.5 0.1 4.5e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KXX79611.1 - 0.043 13.1 0.1 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 KXX79611.1 - 0.12 12.4 0.2 0.63 10.1 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain AAA_22 PF13401.6 KXX79611.1 - 0.13 12.6 0.1 0.44 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 KXX79611.1 - 0.19 10.8 2.0 0.96 8.5 0.6 2.0 1 1 1 2 2 2 0 PAXNEB protein Macoilin PF09726.9 KXX79612.1 - 1.8 7.0 7.0 2.4 6.6 7.0 1.1 1 0 0 1 1 1 0 Macoilin family Vps26 PF03643.15 KXX79613.1 - 9.4e-130 431.5 0.5 1.1e-129 431.3 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KXX79613.1 - 0.00014 21.9 0.7 0.094 12.8 0.7 3.7 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 KXX79613.1 - 0.062 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Nup160 PF11715.8 KXX79614.1 - 3.5e-171 570.5 0.0 4.5e-171 570.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 EF-hand_1 PF00036.32 KXX79616.1 - 1.8e-26 89.7 7.4 1.1e-06 27.7 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KXX79616.1 - 2.5e-22 76.8 7.4 6.8e-05 22.5 0.2 5.4 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 KXX79616.1 - 8.5e-22 77.4 7.9 7.2e-10 39.2 0.0 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KXX79616.1 - 6.7e-20 70.7 10.2 6.6e-10 38.7 0.0 5.1 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KXX79616.1 - 1.6e-16 59.0 4.6 0.00045 19.6 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_10 PF14788.6 KXX79616.1 - 0.048 13.5 0.2 11 6.0 0.0 3.0 2 1 1 3 3 3 0 EF hand EF-hand_9 PF14658.6 KXX79616.1 - 0.062 13.6 0.4 1.8 8.9 0.0 2.9 3 1 0 3 3 3 0 EF-hand domain DIOX_N PF14226.6 KXX79618.1 - 0.052 14.3 0.3 2.1 9.1 0.0 2.2 1 1 1 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal ChaC PF04752.12 KXX79619.1 - 8.1e-54 182.4 0.0 1e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Glyco_hydro_77 PF02446.17 KXX79619.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase RRM_1 PF00076.22 KXX79620.1 - 5.4e-24 83.8 0.1 7.2e-24 83.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX79620.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KXX79620.1 - 0.051 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KXX79620.1 - 0.067 13.2 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif DbpA PF03880.15 KXX79620.1 - 0.094 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain Ribosomal_L6e PF01159.19 KXX79621.1 - 8e-40 135.8 0.2 1.3e-39 135.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e 2-oxoacid_dh PF00198.23 KXX79622.1 - 7.9e-73 244.7 0.0 1.1e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXX79622.1 - 6.8e-18 64.3 0.2 1.4e-17 63.3 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXX79622.1 - 1.6e-13 50.7 0.2 4.5e-13 49.3 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain V-SNARE_C PF12352.8 KXX79623.1 - 9.9e-12 45.0 0.2 9.9e-12 45.0 0.2 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus STAT_alpha PF01017.20 KXX79623.1 - 0.0011 18.9 0.5 0.015 15.2 0.6 2.2 2 1 0 2 2 2 1 STAT protein, all-alpha domain Atg14 PF10186.9 KXX79623.1 - 0.014 14.5 4.9 0.017 14.3 4.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SATase_N PF06426.14 KXX79623.1 - 0.03 14.7 3.4 0.074 13.4 0.7 2.3 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal Spc7 PF08317.11 KXX79623.1 - 0.37 9.6 6.3 0.066 12.1 3.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein CorA PF01544.18 KXX79623.1 - 3.4 6.9 10.6 0.59 9.4 6.3 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein APG6_N PF17675.1 KXX79623.1 - 4.4 7.8 13.0 12 6.5 11.2 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region ACPS PF01648.20 KXX79624.1 - 5.7e-09 36.1 0.1 1.5e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily K-cyclin_vir_C PF09080.10 KXX79624.1 - 0.089 13.2 0.1 0.31 11.5 0.2 1.8 2 0 0 2 2 2 0 K cyclin, C terminal Peptidase_A22B PF04258.13 KXX79625.1 - 2e-53 181.8 3.7 8.7e-35 120.6 0.5 2.3 2 1 0 2 2 2 2 Signal peptide peptidase SUR7 PF06687.12 KXX79626.1 - 7.7e-36 123.7 4.1 8.9e-36 123.5 4.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 KXX79626.1 - 0.0045 16.9 12.5 0.0045 16.9 12.5 1.5 2 0 0 2 2 2 1 Amastin surface glycoprotein Clc-like PF07062.12 KXX79626.1 - 0.084 12.3 5.7 0.13 11.8 5.7 1.3 1 0 0 1 1 1 0 Clc-like DIE2_ALG10 PF04922.12 KXX79626.1 - 0.76 9.0 6.1 1.1 8.4 6.1 1.2 1 0 0 1 1 1 0 DIE2/ALG10 family YfhO PF09586.10 KXX79626.1 - 3.4 5.8 5.6 4.7 5.3 5.6 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ank_4 PF13637.6 KXX79627.1 - 1.5e-10 41.4 0.1 1e-06 29.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX79627.1 - 2.3e-09 36.7 0.8 0.0023 18.3 0.0 4.1 5 1 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 KXX79627.1 - 1.8e-08 34.8 0.3 3.3e-06 27.6 0.2 3.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX79627.1 - 2.1e-06 27.9 0.4 0.068 13.5 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX79627.1 - 2e-05 24.8 0.0 0.19 12.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat HSP70 PF00012.20 KXX79628.1 - 4.2e-11 41.8 0.3 1.3e-09 36.9 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KXX79628.1 - 0.034 12.9 0.1 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Med31 PF05669.12 KXX79629.1 - 3.3e-36 123.2 3.3 3.9e-36 122.9 3.3 1.1 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.18 KXX79630.1 - 4.2e-20 71.3 3.0 4.2e-20 71.3 3.0 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXX79630.1 - 5.7e-09 35.7 0.1 5.7e-09 35.7 0.1 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 KXX79630.1 - 0.0018 18.4 5.3 0.32 11.2 1.5 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 KXX79630.1 - 0.3 11.6 8.4 15 6.3 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double domain Nudix_N_2 PF14803.6 KXX79630.1 - 3 7.8 7.8 0.24 11.4 0.5 2.6 3 0 0 3 3 3 0 Nudix N-terminal Mem_trans PF03547.18 KXX79631.1 - 7.7e-50 169.4 1.0 5.6e-29 100.7 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein Pkinase PF00069.25 KXX79632.1 - 1.4e-50 172.2 0.0 2.4e-48 164.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX79632.1 - 2e-28 99.4 0.0 1.9e-27 96.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KXX79632.1 - 0.0019 17.3 0.1 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KXX79632.1 - 0.004 16.2 0.0 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXX79632.1 - 0.0098 15.2 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXX79632.1 - 0.092 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXX79632.1 - 0.21 11.5 0.1 0.45 10.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_26 PF02156.15 KXX79633.1 - 2.1e-86 290.2 4.0 2.6e-86 289.9 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 KXX79633.1 - 3.1e-28 98.5 0.6 5.2e-28 97.7 0.6 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) Endotoxin_C PF03944.14 KXX79633.1 - 0.17 12.2 0.2 0.33 11.3 0.2 1.4 1 0 0 1 1 1 0 delta endotoxin Cadherin-like PF12733.7 KXX79633.1 - 0.23 12.0 3.0 0.17 12.4 0.3 2.1 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain Transp_cyt_pur PF02133.15 KXX79634.1 - 2.5e-09 36.5 42.3 3.1e-09 36.1 35.5 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1294 PF06961.13 KXX79634.1 - 0.36 11.1 4.4 1.5 9.1 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) His_Phos_2 PF00328.22 KXX79635.1 - 9.2e-09 35.1 0.2 4.2e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF5325 PF17259.2 KXX79635.1 - 0.2 11.6 0.3 0.41 10.6 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Epimerase PF01370.21 KXX79636.1 - 1.4e-17 64.0 0.0 1.8e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX79636.1 - 1.9e-12 46.8 0.0 2.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXX79636.1 - 6.3e-09 35.7 0.0 8.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXX79636.1 - 1e-08 34.7 0.0 3.8e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXX79636.1 - 2.9e-07 30.5 0.0 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KXX79636.1 - 3.7e-06 27.0 0.0 6.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXX79636.1 - 4.6e-06 26.0 0.0 1e-05 24.9 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXX79636.1 - 8.2e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KXX79636.1 - 0.00022 21.5 0.0 0.00035 20.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KXX79636.1 - 0.00093 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 KXX79636.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KXX79636.1 - 0.038 13.5 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KXX79636.1 - 0.045 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TIR_2 PF13676.6 KXX79636.1 - 0.05 14.2 0.2 1.4 9.6 0.0 2.3 2 0 0 2 2 2 0 TIR domain Semialdhyde_dh PF01118.24 KXX79636.1 - 0.098 13.1 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KXX79637.1 - 1.2e-22 80.7 2.1 6.8e-11 42.0 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXX79637.1 - 0.00013 22.1 0.9 0.00044 20.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX79637.1 - 0.00032 20.0 0.0 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX79637.1 - 0.00049 20.6 2.2 0.0014 19.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX79637.1 - 0.00053 19.7 1.4 0.00053 19.7 1.4 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXX79637.1 - 0.03 13.6 0.6 1.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXX79637.1 - 0.057 13.4 0.0 0.22 11.5 0.0 2.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 KXX79637.1 - 0.093 11.8 0.0 1.3 8.0 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase F-box-like PF12937.7 KXX79638.1 - 0.003 17.4 0.1 0.008 16.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX79638.1 - 0.0063 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain AAA_33 PF13671.6 KXX79639.1 - 6e-13 49.2 0.2 8.3e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KXX79639.1 - 5.6e-08 33.1 0.2 1e-07 32.2 0.2 1.4 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KXX79639.1 - 2.6e-07 31.2 0.1 6.4e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXX79639.1 - 0.00019 21.7 0.7 0.00076 19.8 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXX79639.1 - 0.00031 21.2 0.1 0.00079 19.9 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KXX79639.1 - 0.00073 20.0 0.1 0.0027 18.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX79639.1 - 0.0014 19.1 0.2 0.0027 18.1 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KXX79639.1 - 0.0017 18.9 0.0 0.0027 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KXX79639.1 - 0.002 17.9 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase Rad17 PF03215.15 KXX79639.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain dNK PF01712.19 KXX79639.1 - 0.0056 16.6 0.0 0.03 14.2 0.0 1.8 1 1 0 2 2 2 1 Deoxynucleoside kinase APS_kinase PF01583.20 KXX79639.1 - 0.0059 16.5 0.1 0.014 15.3 0.1 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin2 PF13189.6 KXX79639.1 - 0.0071 16.5 0.2 0.017 15.2 0.2 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_14 PF13173.6 KXX79639.1 - 0.0082 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXX79639.1 - 0.011 15.6 0.0 0.05 13.5 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CoaE PF01121.20 KXX79639.1 - 0.02 14.5 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase ABC_tran PF00005.27 KXX79639.1 - 0.021 15.3 0.0 0.027 15.0 0.0 1.3 1 1 0 1 1 1 0 ABC transporter IPT PF01745.16 KXX79639.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_22 PF13401.6 KXX79639.1 - 0.047 14.0 0.0 0.079 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXX79639.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KXX79639.1 - 0.086 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KXX79639.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 KXX79639.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parathyroid PF01279.17 KXX79639.1 - 0.12 13.0 0.2 0.22 12.2 0.2 1.5 1 0 0 1 1 1 0 Parathyroid hormone family tRNA_lig_kinase PF08303.11 KXX79639.1 - 0.12 12.4 0.0 0.6 10.2 0.0 1.9 1 1 0 2 2 2 0 tRNA ligase kinase domain RhoGAP PF00620.27 KXX79640.1 - 1.3e-10 41.3 0.0 1.1e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 RhoGAP domain FAD_binding_7 PF03441.14 KXX79641.1 - 2.9e-46 157.5 0.1 5.5e-46 156.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXX79641.1 - 5.9e-13 49.2 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase GMC_oxred_N PF00732.19 KXX79642.1 - 4.4e-59 200.3 0.0 2.5e-58 197.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX79642.1 - 2.1e-34 119.1 0.0 3.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX79642.1 - 1.9e-05 23.9 3.3 0.0051 15.9 2.4 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXX79642.1 - 2.1e-05 23.8 1.1 3.3e-05 23.1 1.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXX79642.1 - 0.00011 21.9 1.8 0.00047 19.9 1.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX79642.1 - 0.0002 20.7 0.1 0.00057 19.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXX79642.1 - 0.0023 18.1 1.2 0.006 16.8 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX79642.1 - 0.023 14.0 3.2 0.36 10.1 3.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX79642.1 - 0.037 13.3 0.9 0.073 12.3 0.6 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX79642.1 - 0.18 11.8 0.5 0.37 10.8 0.5 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KXX79642.1 - 0.47 9.1 1.2 0.78 8.4 1.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Putative_PNPOx PF01243.20 KXX79644.1 - 8.3e-12 45.1 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.14 KXX79644.1 - 0.042 12.3 0.1 0.049 12.1 0.1 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Pyridox_ox_2 PF12900.7 KXX79644.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.17 KXX79645.1 - 9.2e-74 247.5 0.0 1.3e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXX79645.1 - 4.5e-37 126.5 0.0 9e-37 125.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXX79645.1 - 9.9e-37 125.9 0.0 1.9e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXX79645.1 - 4.2e-15 55.3 0.4 1e-14 54.1 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KXX79645.1 - 8.4e-08 32.0 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXX79645.1 - 1e-06 28.4 0.0 2.5e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KXX79645.1 - 6.7e-06 25.8 0.0 0.053 13.4 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KXX79645.1 - 8e-05 22.7 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KXX79645.1 - 0.015 16.0 0.0 4.6 8.0 0.0 2.7 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_D23 PF16576.5 KXX79645.1 - 0.038 13.2 0.0 5.1 6.2 0.0 2.6 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 KXX79645.1 - 0.076 12.2 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp 4HBT PF03061.22 KXX79646.1 - 3.2e-05 24.2 0.0 7.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily TP_methylase PF00590.20 KXX79647.1 - 4.1e-46 157.6 0.0 9.2e-46 156.5 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 KXX79647.1 - 4.3e-10 38.8 0.1 8.3e-10 37.9 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KXX79647.1 - 2e-09 36.9 0.1 9.7e-08 31.5 0.0 2.5 3 0 0 3 3 3 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KXX79647.1 - 0.0028 18.1 0.0 0.0061 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding TRH PF05438.12 KXX79647.1 - 0.13 12.0 0.3 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) LVIVD PF08309.11 KXX79648.1 - 5.9e-11 41.5 5.2 0.038 13.3 0.0 5.2 5 0 0 5 5 5 4 LVIVD repeat Glyco_hydro_3_C PF01915.22 KXX79649.1 - 4.1e-48 164.0 0.0 9.8e-48 162.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX79649.1 - 7.3e-41 140.6 0.0 1.2e-40 139.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX79649.1 - 2.9e-27 94.6 0.0 5.6e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Podoplanin PF05808.11 KXX79651.1 - 0.0035 17.5 0.2 0.0057 16.8 0.2 1.3 1 0 0 1 1 1 1 Podoplanin MtrF PF09472.10 KXX79651.1 - 0.026 13.9 0.2 0.047 13.1 0.2 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) VSP PF03302.13 KXX79651.1 - 0.035 13.0 0.3 0.049 12.5 0.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Glyco_hydro_3_C PF01915.22 KXX79653.1 - 1.5e-42 145.9 0.0 2.3e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX79653.1 - 2.8e-32 112.4 0.0 4e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX79653.1 - 6.1e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Aminotran_5 PF00266.19 KXX79654.1 - 1.1e-18 67.4 0.0 8e-18 64.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_M54 PF07998.11 KXX79655.1 - 1.3e-11 44.8 0.0 2.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M54 DUF1639 PF07797.14 KXX79655.1 - 0.15 12.1 0.2 0.97 9.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) Arginase PF00491.21 KXX79656.1 - 1.3e-10 41.2 0.0 1.8e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Arginase family Hexokinase_2 PF03727.16 KXX79657.1 - 1.2e-75 254.0 0.0 1.6e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXX79657.1 - 1.1e-74 250.6 0.0 1.5e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Ribosomal_S11 PF00411.19 KXX79657.1 - 0.12 12.8 0.1 0.36 11.3 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S11 MFS_1 PF07690.16 KXX79659.1 - 1.9e-34 119.1 18.0 1.9e-34 119.1 18.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXX79659.1 - 2.3e-08 33.7 1.4 2.3e-08 33.7 1.4 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Spin-Ssty PF02513.17 KXX79659.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Spin/Ssty Family BTB PF00651.31 KXX79660.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF2463 PF09591.10 KXX79661.1 - 0.028 14.3 0.3 0.028 14.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) FAD_binding_4 PF01565.23 KXX79662.1 - 2.6e-21 75.8 1.7 3.7e-21 75.3 0.8 1.7 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KXX79662.1 - 2.1e-12 46.9 0.0 4.5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.7 KXX79663.1 - 2.4e-05 24.1 0.0 5.6e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KXX79663.1 - 0.056 13.4 1.2 9.7 6.2 0.1 2.8 2 0 0 2 2 2 0 F-box domain Mannosyl_trans PF05007.13 KXX79664.1 - 2.5e-08 34.1 0.0 4.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KXX79664.1 - 2.2e-07 30.3 0.4 2.7e-07 30.0 0.4 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KXX79664.1 - 0.01 15.5 11.8 0.018 14.8 11.8 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 SQS_PSY PF00494.19 KXX79665.1 - 1.9e-37 129.2 0.0 4.4e-37 128.0 0.0 1.6 2 0 0 2 2 2 1 Squalene/phytoene synthase Peptidase_S8 PF00082.22 KXX79666.1 - 3.8e-34 118.3 12.8 9.6e-34 117.0 12.8 1.5 1 1 0 1 1 1 1 Subtilase family DnaJ-X PF14308.6 KXX79667.1 - 1.1e-77 260.2 2.0 1.1e-77 260.2 2.0 2.5 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 KXX79667.1 - 4.3e-27 94.0 1.2 9.2e-27 93.0 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2680 PF10925.8 KXX79667.1 - 0.21 11.6 2.4 0.26 11.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) RmlD_sub_bind PF04321.17 KXX79668.1 - 7.4e-15 54.8 0.0 1.3e-14 54.0 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXX79668.1 - 4.8e-14 52.4 0.0 9.5e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXX79668.1 - 0.00021 20.6 0.0 0.00049 19.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX79668.1 - 0.0009 18.7 0.0 0.0038 16.7 0.0 2.0 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXX79668.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Macro PF01661.21 KXX79668.1 - 0.16 12.0 0.0 0.48 10.5 0.0 1.8 1 0 0 1 1 1 0 Macro domain AMP-binding PF00501.28 KXX79669.1 - 4.7e-69 233.0 0.0 6.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX79669.1 - 1.1e-08 35.9 0.1 2.7e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.21 KXX79670.1 - 1.1e-28 99.6 0.0 1.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KXX79670.1 - 1.8e-11 43.7 0.1 3.6e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KXX79670.1 - 1.8e-11 43.9 0.0 2.4e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 KXX79670.1 - 0.097 12.6 0.0 0.22 11.5 0.0 1.5 2 0 0 2 2 2 0 SCO1/SenC Kelch_4 PF13418.6 KXX79671.1 - 1e-15 57.5 0.1 1.1e-05 25.3 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KXX79671.1 - 1.5e-14 53.9 2.5 1.9e-08 34.4 0.0 5.8 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KXX79671.1 - 1.5e-13 50.4 6.3 7.9e-07 28.9 0.0 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KXX79671.1 - 6.2e-13 48.1 0.1 0.00063 19.3 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KXX79671.1 - 2.6e-12 46.5 2.5 0.00056 20.1 0.4 5.0 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KXX79671.1 - 1.7e-07 30.9 0.2 0.007 16.3 0.0 4.4 3 1 0 3 3 3 1 Kelch motif BTB PF00651.31 KXX79671.1 - 0.0095 16.2 0.0 0.083 13.1 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain AMP-binding PF00501.28 KXX79672.1 - 6e-97 324.9 0.0 7.7e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX79672.1 - 3.4e-13 50.3 0.0 8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.6 KXX79673.1 - 4.4e-20 71.8 0.1 9.9e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 KXX79674.1 - 1.4e-25 90.2 0.0 3.2e-25 89.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX79674.1 - 6.7e-14 52.2 0.2 9.1e-11 42.2 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX79674.1 - 3.2e-05 23.4 1.1 0.055 12.7 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KXX79674.1 - 0.00012 21.4 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXX79674.1 - 0.0005 19.3 1.0 0.00091 18.5 0.3 1.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXX79674.1 - 0.0027 16.8 0.2 0.0064 15.6 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KXX79674.1 - 0.0032 17.1 1.0 0.27 10.8 0.2 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX79674.1 - 0.007 16.6 0.0 1.9 8.8 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXX79674.1 - 0.028 14.4 1.8 2.5 8.0 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXX79674.1 - 0.032 13.1 0.8 0.69 8.7 0.3 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Amino_oxidase PF01593.24 KXX79674.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KXX79674.1 - 0.15 11.1 0.1 7.3 5.5 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXX79674.1 - 0.31 9.7 0.7 1.5 7.4 0.1 2.2 3 0 0 3 3 3 0 HI0933-like protein Sugar_tr PF00083.24 KXX79675.1 - 1.6e-94 317.3 17.4 1.9e-94 317.1 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX79675.1 - 6.6e-24 84.5 33.2 6e-23 81.3 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KXX79676.1 - 6.7e-40 136.6 0.0 8.2e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX79676.1 - 1e-27 97.2 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX79676.1 - 3.2e-07 30.4 0.0 4.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX79676.1 - 0.0089 15.5 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Imm5 PF14423.6 KXX79676.1 - 0.22 11.7 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 p450 PF00067.22 KXX79677.1 - 2.6e-15 56.2 0.0 5e-10 38.7 0.0 2.7 3 0 0 3 3 3 2 Cytochrome P450 PIG-S PF10510.9 KXX79678.1 - 4.8e-169 563.5 0.0 5.7e-169 563.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein WD40 PF00400.32 KXX79680.1 - 8.4e-12 45.4 7.2 8.3e-05 23.3 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Translin PF01997.16 KXX79681.1 - 7.1e-65 218.8 0.0 8.5e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Translin family EF1_GNE PF00736.19 KXX79682.1 - 1.3e-32 111.8 1.0 2.1e-32 111.2 1.0 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KXX79682.1 - 8.2e-14 51.8 9.4 8.2e-14 51.8 9.4 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KXX79682.1 - 0.00031 20.9 0.6 0.0023 18.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain UBA2_C PF16195.5 KXX79682.1 - 0.26 12.0 4.5 0.44 11.3 4.5 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus GST_C PF00043.25 KXX79682.1 - 0.3 11.3 0.1 0.3 11.3 0.1 2.5 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF1996 PF09362.10 KXX79683.1 - 5.9e-82 275.2 0.7 7.1e-82 274.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf_Rg PF17915.1 KXX79683.1 - 1.6 8.2 7.1 1.1 8.7 0.5 2.8 3 0 0 3 3 3 0 Reverse gyrase zinc finger GMC_oxred_N PF00732.19 KXX79684.1 - 1.9e-60 204.7 0.0 2.5e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX79684.1 - 1.1e-31 110.3 0.0 1.9e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXX79684.1 - 1.2e-05 25.4 0.3 3e-05 24.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX79684.1 - 1.5e-05 24.3 3.5 0.00029 20.0 3.5 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX79684.1 - 3.9e-05 23.0 1.0 0.00069 18.9 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX79684.1 - 0.00022 20.6 0.6 0.48 9.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX79684.1 - 0.00032 19.5 0.5 0.005 15.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KXX79684.1 - 0.0045 16.3 0.1 0.011 15.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXX79684.1 - 0.0056 15.8 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXX79684.1 - 0.006 16.2 2.5 0.038 13.6 0.5 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KXX79684.1 - 0.036 13.2 0.9 0.78 8.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXX79684.1 - 0.039 13.2 0.1 0.079 12.2 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KXX79684.1 - 0.041 12.7 0.1 0.061 12.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 KXX79684.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Amidohydro_2 PF04909.14 KXX79685.1 - 2.6e-41 142.3 2.1 3.1e-41 142.1 2.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Metal_resist PF13801.6 KXX79685.1 - 0.0017 18.5 1.3 0.0036 17.5 1.3 1.6 1 0 0 1 1 1 1 Heavy-metal resistance HEV_ORF1 PF02444.16 KXX79686.1 - 0.26 11.9 4.5 0.75 10.4 4.5 1.9 1 1 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) Complex1_LYR PF05347.15 KXX79687.1 - 4.7e-18 65.0 0.1 5.9e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXX79687.1 - 2.3e-07 31.5 0.0 2.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_L36 PF00444.18 KXX79688.1 - 1.9e-20 72.8 10.5 2.7e-20 72.3 10.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 PLAC8 PF04749.17 KXX79689.1 - 2.7e-14 54.0 1.8 3.3e-14 53.7 1.8 1.1 1 0 0 1 1 1 1 PLAC8 family Acetyltransf_1 PF00583.25 KXX79690.1 - 1.3e-11 44.8 0.0 1.7e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX79690.1 - 1.2e-07 32.1 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX79690.1 - 2.9e-05 24.0 0.0 4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX79690.1 - 8.6e-05 22.4 0.0 0.00056 19.8 0.0 2.1 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 KXX79690.1 - 0.0033 18.1 0.0 0.0045 17.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXX79690.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CTP_transf_like PF01467.26 KXX79692.1 - 5.7e-05 23.3 0.0 0.00018 21.7 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like WD40 PF00400.32 KXX79694.1 - 0.0046 17.8 1.6 0.03 15.2 0.1 2.5 2 1 0 2 2 2 1 WD domain, G-beta repeat Cyclin PF08613.11 KXX79695.1 - 7.7e-41 140.1 10.2 6.4e-25 88.4 0.3 3.0 3 0 0 3 3 3 2 Cyclin RRN3 PF05327.11 KXX79695.1 - 0.028 13.0 2.6 0.041 12.4 2.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 KXX79695.1 - 0.71 7.9 11.5 1 7.4 11.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KXX79695.1 - 1.5 8.5 15.8 0.012 15.4 5.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KXX79695.1 - 7.2 5.8 15.6 11 5.2 15.6 1.2 1 0 0 1 1 1 0 NOA36 protein RAP1 PF07218.11 KXX79695.1 - 8.8 4.5 11.7 19 3.4 11.7 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SET PF00856.28 KXX79696.1 - 2.4e-10 41.0 0.0 5.2e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 SET domain PSCyt2 PF07583.11 KXX79696.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Sugar_tr PF00083.24 KXX79697.1 - 3.8e-93 312.8 22.5 4.8e-93 312.5 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX79697.1 - 8.2e-14 51.3 45.4 8.7e-08 31.5 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF2_C PF09173.11 KXX79697.1 - 0.059 13.6 0.0 0.21 11.8 0.0 2.0 1 1 1 2 2 2 0 Initiation factor eIF2 gamma, C terminal DUF3445 PF11927.8 KXX79698.1 - 5.6e-65 219.1 0.0 6.8e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Pyr_redox_2 PF07992.14 KXX79699.1 - 8.5e-35 120.4 0.0 1.1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX79699.1 - 3.7e-18 65.9 0.1 3.2e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX79699.1 - 3.8e-07 30.0 0.8 0.031 13.8 0.1 3.6 3 1 0 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXX79699.1 - 9.6e-06 24.7 0.0 0.069 12.0 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXX79699.1 - 1.1e-05 24.8 0.0 0.00052 19.4 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX79699.1 - 1.4e-05 25.1 0.7 2.3 8.2 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXX79699.1 - 3e-05 23.4 0.0 5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXX79699.1 - 0.00023 21.3 0.1 0.51 10.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KXX79699.1 - 0.00093 19.6 0.0 0.87 10.1 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KXX79699.1 - 0.0032 16.6 0.0 0.17 10.9 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein ApbA PF02558.16 KXX79699.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KXX79699.1 - 0.048 13.0 0.2 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KXX79699.1 - 0.055 13.7 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain DUF1188 PF06690.11 KXX79699.1 - 0.17 11.4 0.0 3.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Abhydrolase_3 PF07859.13 KXX79701.1 - 1.1e-13 51.5 0.1 1.7e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX79702.1 - 0.012 15.1 0.0 0.034 13.6 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXX79702.1 - 0.062 12.9 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3336 PF11815.8 KXX79703.1 - 1.5e-35 121.9 0.2 2.8e-35 121.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXX79703.1 - 1.7e-20 74.1 0.1 3.3e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase TMEM154 PF15102.6 KXX79704.1 - 1.5 8.7 0.0 1.5 8.7 0.0 2.3 1 1 1 2 2 2 0 TMEM154 protein family Glyco_hydro_61 PF03443.14 KXX79706.1 - 2e-63 214.0 0.1 2.5e-63 213.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 KXX79706.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) DHO_dh PF01180.21 KXX79707.1 - 1.5e-67 227.9 0.0 6e-67 225.9 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.17 KXX79707.1 - 0.045 13.2 0.7 7.5 5.9 0.0 2.3 2 0 0 2 2 2 0 PcrB family FMN_dh PF01070.18 KXX79707.1 - 0.048 12.7 2.8 0.53 9.3 2.2 2.3 2 1 0 2 2 2 0 FMN-dependent dehydrogenase HRI1 PF16815.5 KXX79708.1 - 1.4e-68 231.0 0.4 1.6e-68 230.9 0.4 1.0 1 0 0 1 1 1 1 Protein HRI1 GCR1_C PF12550.8 KXX79709.1 - 1.9e-19 69.7 0.9 2.5e-19 69.4 0.9 1.3 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes F5_F8_type_C PF00754.25 KXX79709.1 - 0.0003 20.9 0.5 0.00041 20.5 0.5 1.2 1 0 0 1 1 1 1 F5/8 type C domain AHSA1 PF08327.11 KXX79709.1 - 0.042 14.1 0.2 0.053 13.7 0.2 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein CCM2_C PF16545.5 KXX79709.1 - 0.098 13.2 0.5 0.14 12.7 0.5 1.2 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology TMEM240 PF15207.6 KXX79709.1 - 0.18 11.5 1.1 0.29 10.8 1.1 1.3 1 0 0 1 1 1 0 TMEM240 family ketoacyl-synt PF00109.26 KXX79710.1 - 5.6e-67 226.0 0.4 1.7e-66 224.4 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXX79710.1 - 2.9e-56 191.3 0.1 7.5e-56 189.9 0.1 1.7 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KXX79710.1 - 1.7e-55 187.7 0.1 4.9e-55 186.2 0.1 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXX79710.1 - 9.6e-40 136.7 2.0 1.6e-39 135.9 2.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXX79710.1 - 2.3e-38 130.8 0.0 6.5e-38 129.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KXX79710.1 - 5.7e-17 63.0 0.0 3.5e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXX79710.1 - 8.5e-17 61.6 0.1 1e-14 54.9 0.0 3.5 3 1 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KXX79710.1 - 3.7e-16 59.7 0.0 1e-15 58.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX79710.1 - 2.3e-14 53.3 0.0 6.8e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KXX79710.1 - 2e-12 47.2 1.3 6.1e-12 45.6 0.2 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KXX79710.1 - 1.9e-10 40.9 0.0 9.5e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KXX79710.1 - 2.7e-10 40.3 0.0 6.3e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXX79710.1 - 6.6e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 KXX79710.1 - 8.4e-07 29.6 0.0 2.5e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX79710.1 - 1.2e-06 29.1 0.0 4.1e-06 27.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX79710.1 - 2.4e-05 24.1 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KXX79710.1 - 0.00011 22.0 0.5 0.00028 20.7 0.5 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KXX79710.1 - 0.00051 19.8 0.3 0.0015 18.4 0.3 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KXX79710.1 - 0.021 14.2 0.2 0.066 12.6 0.0 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain Methyltransf_28 PF02636.17 KXX79710.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase p450 PF00067.22 KXX79712.1 - 2.3e-55 188.2 0.0 3.1e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RPM2 PF08579.11 KXX79712.1 - 0.0027 18.1 0.1 0.76 10.2 0.1 2.2 1 1 0 2 2 2 2 Mitochondrial ribonuclease P subunit (RPM2) FSH1 PF03959.13 KXX79713.1 - 5.8e-33 114.3 0.0 6.8e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXX79713.1 - 0.047 14.3 0.0 0.058 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX79713.1 - 0.41 10.4 1.6 0.67 9.7 0.3 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 KXX79714.1 - 2e-26 92.8 27.2 2e-26 92.8 27.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX79714.1 - 4.8e-12 45.1 7.3 4.5e-10 38.6 5.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXX79714.1 - 0.0024 16.3 2.7 0.0024 16.3 2.7 2.6 2 1 0 3 3 3 1 Transmembrane secretion effector EMC3_TMCO1 PF01956.16 KXX79714.1 - 0.036 13.8 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2070 PF09843.9 KXX79714.1 - 0.26 9.5 6.9 0.41 8.9 0.7 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) adh_short PF00106.25 KXX79715.1 - 7.3e-45 152.8 1.8 1e-44 152.4 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX79715.1 - 2.3e-33 115.7 0.4 2.8e-33 115.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX79715.1 - 3.3e-07 30.4 0.4 5.9e-07 29.6 0.4 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXX79715.1 - 6.2e-05 23.0 0.1 0.00024 21.0 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KXX79715.1 - 0.005 16.8 1.0 0.0089 16.0 0.2 1.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KXX79715.1 - 0.022 14.3 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KXX79715.1 - 0.046 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KXX79715.1 - 0.056 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-RING_2 PF13639.6 KXX79716.1 - 2.5e-09 37.3 8.2 4.9e-09 36.4 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXX79716.1 - 3.7e-08 33.5 7.1 9.2e-08 32.3 7.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 KXX79716.1 - 2.8e-06 27.4 8.7 1.1e-05 25.5 8.7 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 KXX79716.1 - 1.1e-05 25.2 8.7 2.1e-05 24.3 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXX79716.1 - 2.1e-05 24.5 3.1 2.1e-05 24.5 3.1 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KXX79716.1 - 0.00056 19.7 8.0 0.00056 19.7 8.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXX79716.1 - 0.0014 18.2 5.6 0.0027 17.3 5.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KXX79716.1 - 0.0022 18.0 5.3 0.0048 16.9 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXX79716.1 - 0.0046 16.8 5.4 0.0078 16.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KXX79716.1 - 0.008 16.3 7.3 0.019 15.1 7.3 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 KXX79716.1 - 0.065 13.6 8.5 0.12 12.7 8.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KXX79716.1 - 0.11 12.3 4.8 0.27 11.0 4.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 KXX79716.1 - 0.33 10.8 3.9 0.68 9.8 3.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KXX79716.1 - 0.72 9.8 5.5 1.7 8.6 5.5 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 C1_1 PF00130.22 KXX79716.1 - 1.1 9.2 5.9 0.79 9.7 4.2 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TetR_C_30 PF17939.1 KXX79716.1 - 1.3 9.2 4.6 6.9 6.9 0.0 4.6 5 1 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain zf-RING_5 PF14634.6 KXX79716.1 - 3.4 7.7 8.6 6.3 6.9 8.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FlaF PF07309.11 KXX79716.1 - 4.4 7.4 4.8 1.6 8.8 0.0 2.8 4 0 0 4 4 2 0 Flagellar protein FlaF PHD PF00628.29 KXX79716.1 - 5.9 6.9 7.2 10 6.1 7.2 1.4 1 0 0 1 1 1 0 PHD-finger COesterase PF00135.28 KXX79717.1 - 2.2e-79 267.7 0.0 3.5e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_3 PF01494.19 KXX79717.1 - 1.3e-15 57.5 0.0 3.5e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Abhydrolase_3 PF07859.13 KXX79717.1 - 1.4e-09 38.1 0.0 4e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX79717.1 - 0.0055 16.2 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family NAD_binding_8 PF13450.6 KXX79717.1 - 0.019 15.2 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXX79717.1 - 0.019 14.3 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Hexapep PF00132.24 KXX79718.1 - 4.9e-14 51.4 4.7 5.9e-11 41.6 3.7 2.8 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KXX79718.1 - 2.8e-13 49.9 0.0 5.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KXX79718.1 - 9.5e-12 44.5 3.7 1.9e-08 33.9 2.6 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase TORC_C PF12886.7 KXX79718.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Transducer of regulated CREB activity, C terminus UDPGT PF00201.18 KXX79719.1 - 2.7e-19 69.4 0.0 5.5e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXX79719.1 - 0.00014 21.9 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Phage_tail_APC PF16778.5 KXX79719.1 - 0.0049 16.7 0.3 0.029 14.2 0.0 2.3 2 0 0 2 2 2 1 Phage tail assembly chaperone protein Glyco_trans_1_3 PF13528.6 KXX79719.1 - 0.074 12.3 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 1 SKG6 PF08693.10 KXX79721.1 - 2.1e-05 23.8 1.1 4.1e-05 22.9 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 KXX79721.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Metallophos PF00149.28 KXX79722.1 - 2.3e-09 38.1 0.0 4.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX79722.1 - 0.00022 21.5 0.9 0.0081 16.4 0.9 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SH3_3 PF08239.11 KXX79723.1 - 2.6e-06 27.6 0.1 5.2e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain NLPC_P60 PF00877.19 KXX79723.1 - 0.0038 17.2 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family SH3_4 PF06347.13 KXX79723.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain MFS_1 PF07690.16 KXX79724.1 - 2.6e-36 125.3 46.7 1.7e-28 99.6 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX79724.1 - 3.3e-12 46.0 13.7 3.3e-12 46.0 13.7 2.7 2 0 0 2 2 2 2 Sugar (and other) transporter MTABC_N PF16185.5 KXX79724.1 - 0.0058 16.2 8.6 0.47 9.9 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial ABC-transporter N-terminal five TM region Lipase_3 PF01764.25 KXX79725.1 - 3.1e-09 36.8 0.0 4.1e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KXX79725.1 - 0.0065 16.2 0.0 0.0088 15.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXX79725.1 - 0.021 15.4 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 KXX79725.1 - 0.21 11.1 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FAD_binding_3 PF01494.19 KXX79728.1 - 2.2e-10 40.3 0.9 2.5e-08 33.5 0.9 2.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX79728.1 - 6.2e-07 28.9 0.0 5.4e-05 22.6 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX79728.1 - 2.6e-06 27.6 0.1 5.3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX79728.1 - 0.00011 21.9 0.6 0.00024 20.8 0.5 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 KXX79728.1 - 0.022 14.4 0.2 0.053 13.2 0.2 1.6 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KXX79728.1 - 0.033 13.3 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KXX79728.1 - 0.047 13.7 0.1 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXX79728.1 - 0.072 13.7 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX79728.1 - 0.11 11.5 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein LPD24 PF18839.1 KXX79728.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 Thi4 PF01946.17 KXX79728.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.15 KXX79728.1 - 0.24 9.9 0.0 0.35 9.4 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) p450 PF00067.22 KXX79730.1 - 3.5e-48 164.5 0.0 5.3e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KXX79732.1 - 9.7e-77 258.0 0.0 1.7e-76 257.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX79732.1 - 1e-61 208.0 0.1 3e-61 206.5 0.1 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXX79732.1 - 3.8e-60 203.6 0.0 7.5e-60 202.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX79732.1 - 1.5e-48 165.9 0.1 4.1e-48 164.5 0.1 1.7 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX79732.1 - 7.2e-40 135.7 0.1 1.7e-39 134.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXX79732.1 - 9e-22 77.7 0.0 2.5e-21 76.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXX79732.1 - 1.9e-20 74.3 0.0 1.1e-18 68.5 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX79732.1 - 3.6e-18 65.8 0.0 2.7e-17 63.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXX79732.1 - 8.8e-14 51.4 0.3 1.2e-11 44.5 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KXX79732.1 - 1.7e-13 51.0 0.0 9.8e-13 48.5 0.0 2.2 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXX79732.1 - 1.3e-12 48.2 0.0 7.5e-11 42.6 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX79732.1 - 4e-11 43.0 0.0 8.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX79732.1 - 1.1e-09 38.8 0.0 4e-09 37.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXX79732.1 - 2e-07 30.8 0.3 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KXX79732.1 - 3e-07 30.3 0.7 7.3e-07 29.0 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 KXX79732.1 - 4e-07 29.9 0.0 1.4e-06 28.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX79732.1 - 2.3e-05 23.9 0.0 4.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KXX79732.1 - 3.5e-05 24.1 0.2 8.5e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXX79732.1 - 4.7e-05 22.9 0.0 9.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PALP PF00291.25 KXX79732.1 - 0.016 14.6 0.3 0.093 12.1 0.1 2.3 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.10 KXX79732.1 - 0.032 14.4 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Epimerase PF01370.21 KXX79732.1 - 0.061 12.8 0.1 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CoA_trans PF01144.23 KXX79732.1 - 0.12 11.7 0.0 0.35 10.2 0.0 1.7 1 0 0 1 1 1 0 Coenzyme A transferase F420_oxidored PF03807.17 KXX79732.1 - 0.19 12.4 0.3 1.8 9.2 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Palm_thioest PF02089.15 KXX79733.1 - 5.5e-78 262.1 0.0 6.5e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KXX79733.1 - 0.015 14.7 0.0 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 KXX79733.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold SF3A3 PF16837.5 KXX79733.1 - 0.053 14.0 0.8 2.2 8.9 0.4 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Ribosomal_L1 PF00687.21 KXX79734.1 - 3.4e-65 219.6 0.6 3.4e-65 219.6 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family p450 PF00067.22 KXX79735.1 - 9.6e-63 212.5 0.0 1.3e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OrfB_Zn_ribbon PF07282.11 KXX79737.1 - 0.0027 17.6 9.9 0.48 10.4 0.1 4.0 2 2 1 4 4 4 2 Putative transposase DNA-binding domain DZR PF12773.7 KXX79737.1 - 0.0029 17.6 10.0 0.15 12.1 3.9 2.7 1 1 2 3 3 3 3 Double zinc ribbon ADD_DNMT3 PF17980.1 KXX79737.1 - 0.073 13.1 1.8 1.3 9.1 0.2 2.6 3 0 0 3 3 3 0 Cysteine rich ADD domain in DNMT3 Zn-ribbon_8 PF09723.10 KXX79737.1 - 1 9.6 13.4 36 4.6 4.7 4.5 2 1 1 4 4 4 0 Zinc ribbon domain PADR1 PF08063.12 KXX79737.1 - 1 9.2 8.9 1.4 8.8 0.8 3.2 3 0 0 3 3 3 0 PADR1 (NUC008) domain ResIII PF04851.15 KXX79739.1 - 1.6e-24 86.8 0.0 8.4e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXX79739.1 - 2.3e-23 82.6 0.0 5.2e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX79739.1 - 1.5e-16 60.7 0.0 3.3e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KXX79739.1 - 9.3e-05 22.2 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KXX79739.1 - 0.0035 17.6 0.0 0.015 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain Spem1 PF15670.5 KXX79739.1 - 1.5 8.3 3.6 23 4.5 0.0 2.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 PMT PF02366.18 KXX79740.1 - 8.4e-84 281.0 16.0 1.6e-83 280.0 16.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXX79740.1 - 6.2e-68 228.3 10.6 6.2e-68 228.3 10.6 2.9 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXX79740.1 - 1e-18 67.9 0.4 1.8e-18 67.1 0.4 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KXX79740.1 - 0.0017 18.6 9.8 0.0017 18.6 9.8 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase zf-C2H2 PF00096.26 KXX79741.1 - 0.0079 16.6 2.7 0.0079 16.6 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KXX79741.1 - 0.035 13.8 0.2 0.035 13.8 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Ank_4 PF13637.6 KXX79742.1 - 1.1e-15 57.8 2.3 3.4e-08 33.9 0.1 4.0 2 1 2 4 4 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX79742.1 - 4.8e-13 49.5 0.3 2.8e-12 47.0 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) NACHT PF05729.12 KXX79742.1 - 3.8e-12 46.4 0.2 1.3e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Ank PF00023.30 KXX79742.1 - 2.5e-11 43.5 2.0 0.0018 18.7 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXX79742.1 - 1.1e-09 37.6 0.9 0.084 13.5 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXX79742.1 - 2.2e-08 34.2 0.2 0.029 14.7 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KXX79742.1 - 4.4e-08 32.7 0.4 1.9e-07 30.6 0.4 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 KXX79742.1 - 5.4e-05 23.6 0.0 0.00055 20.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX79742.1 - 0.0034 17.7 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXX79742.1 - 0.0047 16.9 0.0 0.15 12.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXX79742.1 - 0.0081 16.1 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KXX79742.1 - 0.055 12.7 0.0 0.16 11.1 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain TcdA_TcdB PF12919.7 KXX79742.1 - 0.13 11.5 0.0 1.9 7.7 0.0 2.6 2 1 1 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain zf_C2H2_13 PF18508.1 KXX79742.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Zinc finger domain CdvA PF18822.1 KXX79742.1 - 5.6 6.8 6.4 6.2 6.7 0.2 2.7 3 0 0 3 3 3 0 CdvA-like coiled-coil domain MSC PF09402.10 KXX79743.1 - 3.1e-114 382.0 0.0 3.6e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain TAP_C PF03943.13 KXX79744.1 - 2.2e-17 62.4 0.7 4.1e-17 61.5 0.7 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 KXX79744.1 - 2.4e-10 40.5 0.7 8.3e-06 26.1 0.1 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 KXX79744.1 - 5.3e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif LRR_8 PF13855.6 KXX79744.1 - 5.2e-06 26.1 0.3 1.5e-05 24.7 0.3 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 KXX79744.1 - 1.6e-05 24.6 0.4 0.14 12.3 0.2 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KXX79744.1 - 3.5e-05 23.4 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KXX79744.1 - 0.0056 17.1 2.4 2 9.3 0.6 2.9 2 0 0 2 2 2 2 Leucine Rich Repeat HEAT_2 PF13646.6 KXX79744.1 - 0.045 14.1 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 HEAT repeats Kelch_6 PF13964.6 KXX79745.1 - 0.0031 17.7 2.4 0.12 12.7 0.0 4.1 5 0 0 5 5 5 1 Kelch motif TMEM154 PF15102.6 KXX79745.1 - 0.023 14.6 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family FMN_dh PF01070.18 KXX79746.1 - 1.6e-106 356.3 0.1 2.3e-106 355.7 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXX79746.1 - 0.00015 21.0 0.2 0.00023 20.4 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXX79746.1 - 0.00024 20.2 1.5 0.0012 18.0 0.4 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXX79746.1 - 0.00041 19.8 3.4 0.00062 19.3 3.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KXX79746.1 - 0.3 10.4 2.9 0.2 10.9 0.3 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DAHP_synth_1 PF00793.20 KXX79747.1 - 1.7e-101 338.7 0.1 2.1e-101 338.4 0.1 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Dynamin_M PF01031.20 KXX79749.1 - 5e-111 370.5 0.0 1.3e-110 369.2 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KXX79749.1 - 2.4e-56 190.4 0.0 6e-56 189.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXX79749.1 - 6.8e-31 106.3 2.7 6.8e-31 106.3 2.7 2.1 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXX79749.1 - 5e-05 23.3 0.4 0.00065 19.8 0.4 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ligase_CoA PF00549.19 KXX79750.1 - 9e-26 90.5 2.8 4.9e-15 55.7 0.0 3.9 4 0 0 4 4 4 3 CoA-ligase CoA_binding PF02629.19 KXX79750.1 - 6.4e-17 62.0 0.3 2.4e-16 60.2 0.3 2.0 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 KXX79750.1 - 1.6e-06 28.0 0.4 5.3e-05 23.0 0.0 3.1 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CHCH PF06747.13 KXX79750.1 - 0.049 13.8 1.2 0.12 12.6 1.2 1.6 1 1 1 2 2 2 0 CHCH domain MFS_1 PF07690.16 KXX79751.1 - 3.4e-20 72.3 56.6 3.4e-20 72.3 56.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LIM PF00412.22 KXX79752.1 - 1.4e-25 89.3 23.7 6.9e-09 35.8 1.3 3.5 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.9 KXX79752.1 - 0.01 15.4 0.2 0.01 15.4 0.2 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Auto_anti-p27 PF06677.12 KXX79752.1 - 0.22 11.7 2.0 6.2 7.1 0.5 3.1 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Nudix_N_2 PF14803.6 KXX79752.1 - 3 7.9 16.1 2.5 8.1 1.4 5.1 5 0 0 5 5 5 0 Nudix N-terminal Rad60-SLD PF11976.8 KXX79753.1 - 2.2e-18 65.8 0.1 2.6e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXX79753.1 - 8.7e-11 41.4 0.1 1e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.18 KXX79753.1 - 0.088 12.5 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain MTCP1 PF08991.10 KXX79754.1 - 1.5e-29 102.0 7.0 1.8e-29 101.7 7.0 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KXX79754.1 - 0.0011 19.0 6.8 0.0011 19.0 5.4 1.8 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.10 KXX79754.1 - 0.3 11.2 6.9 0.15 12.1 2.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nup84_Nup100 PF04121.13 KXX79755.1 - 5.3e-204 679.4 0.3 6.1e-204 679.2 0.3 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Cytochrom_C1 PF02167.15 KXX79756.1 - 1.6e-93 312.4 0.0 2e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KXX79756.1 - 0.0043 17.3 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KXX79756.1 - 0.028 15.5 0.0 0.11 13.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c GreA_GreB_N PF03449.15 KXX79756.1 - 0.095 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Pro_isomerase PF00160.21 KXX79757.1 - 2.5e-51 174.1 0.4 8.4e-51 172.4 0.1 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KXX79757.1 - 4.5e-09 36.8 0.0 0.00013 22.7 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79757.1 - 0.003 17.8 0.0 0.083 13.2 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX79757.1 - 0.044 12.7 0.3 1.8 7.4 0.1 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short_C2 PF13561.6 KXX79758.1 - 1.3e-55 188.5 0.0 1.8e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX79758.1 - 8.6e-44 149.3 0.0 1.1e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX79758.1 - 1.5e-10 41.3 0.0 2.1e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXX79758.1 - 0.0051 16.2 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 KXX79758.1 - 0.029 13.8 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme HhH-GPD PF00730.25 KXX79759.1 - 4.8e-06 27.0 0.0 8.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein zf-B_box PF00643.24 KXX79760.1 - 0.085 13.0 6.3 0.21 11.7 6.3 1.6 1 0 0 1 1 1 0 B-box zinc finger ABC_tran PF00005.27 KXX79761.1 - 7.6e-52 175.5 0.0 6.5e-32 110.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXX79761.1 - 1.4e-35 123.3 31.3 6e-26 91.7 19.3 3.0 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KXX79761.1 - 4e-08 33.0 0.0 0.0098 15.3 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXX79761.1 - 3.1e-05 23.6 0.7 0.13 12.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX79761.1 - 5.1e-05 23.6 0.0 1.2 9.4 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KXX79761.1 - 9.6e-05 23.0 3.3 0.024 15.2 0.0 2.6 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 KXX79761.1 - 0.00022 21.4 5.0 0.013 15.6 0.2 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 KXX79761.1 - 0.00027 20.9 0.1 1.3 8.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXX79761.1 - 0.00043 19.9 0.4 6.9 6.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KXX79761.1 - 0.00066 19.7 1.1 0.4 10.8 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX79761.1 - 0.00084 19.3 0.1 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXX79761.1 - 0.0014 19.0 1.1 2.7 8.3 0.1 3.2 3 1 0 3 3 2 2 AAA ATPase domain T2SSE PF00437.20 KXX79761.1 - 0.0078 15.3 0.3 0.2 10.7 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 KXX79761.1 - 0.014 14.7 0.2 1.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KXX79761.1 - 0.035 13.5 0.2 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KXX79761.1 - 0.037 14.0 1.4 3.1 7.7 0.6 2.7 2 0 0 2 2 2 0 NACHT domain Phytase PF02333.15 KXX79761.1 - 0.05 12.6 0.2 0.09 11.7 0.2 1.4 1 0 0 1 1 1 0 Phytase MeaB PF03308.16 KXX79761.1 - 0.064 12.2 3.0 0.12 11.4 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KXX79761.1 - 0.13 11.5 1.2 0.53 9.5 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KXX79761.1 - 0.16 11.1 2.8 2.7 7.1 0.1 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_18 PF13238.6 KXX79761.1 - 0.2 12.2 0.1 34 5.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 KXX79761.1 - 0.46 10.5 1.5 32 4.6 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain p450 PF00067.22 KXX79762.1 - 2.3e-80 270.6 0.0 3.1e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1506 PF07405.11 KXX79762.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) Myb_DNA-bind_6 PF13921.6 KXX79763.1 - 6.5e-05 23.1 0.1 0.0001 22.4 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXX79763.1 - 0.0061 16.7 0.5 0.0097 16.1 0.5 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KXX79763.1 - 0.0094 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ribonuc_L-PSP PF01042.21 KXX79764.1 - 3.4e-38 130.4 0.3 4.6e-38 130.0 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP SR-25 PF10500.9 KXX79765.1 - 0.046 13.3 0.4 0.068 12.8 0.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mso1_Sec1_bdg PF14475.6 KXX79765.1 - 0.21 11.2 0.5 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Sec1-binding region of Mso1 IATP PF04568.12 KXX79766.1 - 0.35 11.3 3.1 0.66 10.4 3.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Alpha-amylase PF00128.24 KXX79767.1 - 2.4e-58 198.3 0.0 3.3e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 KXX79767.1 - 3.2e-26 91.0 0.2 7.4e-26 89.9 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 KXX79767.1 - 1.1e-21 76.9 0.4 5.4e-21 74.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1966) IL34 PF15036.6 KXX79767.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 Fungal_trans PF04082.18 KXX79768.1 - 5.8e-18 64.9 0.1 1e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX79768.1 - 0.00075 19.6 10.9 0.0013 18.8 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glutaredoxin PF00462.24 KXX79769.1 - 3.5e-17 62.4 0.0 1.7e-16 60.2 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KXX79769.1 - 5.6e-12 45.6 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KXX79769.1 - 0.11 12.5 0.0 0.73 9.8 0.0 2.3 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KXX79769.1 - 0.19 12.1 0.0 14 6.1 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like SH3_9 PF14604.6 KXX79770.1 - 2.9e-29 100.7 3.3 6.1e-14 51.6 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXX79770.1 - 7.3e-27 92.7 3.8 7.8e-13 47.8 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXX79770.1 - 2.2e-16 59.3 0.0 2e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KXX79770.1 - 2.6e-16 59.5 0.0 4.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mod_r PF07200.13 KXX79771.1 - 3.5e-35 121.3 1.3 4.2e-35 121.0 1.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KXX79771.1 - 0.016 14.1 0.3 0.02 13.8 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PrgH PF09480.10 KXX79774.1 - 0.062 12.6 0.2 0.063 12.6 0.2 1.0 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) SR-25 PF10500.9 KXX79774.1 - 0.097 12.3 8.3 0.092 12.3 8.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLASP_N PF12348.8 KXX79775.1 - 9.1e-138 457.2 0.1 3.3e-90 301.6 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KXX79775.1 - 3.8e-06 26.7 0.4 0.37 11.2 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KXX79775.1 - 0.0001 22.6 1.2 0.49 10.8 0.0 4.2 3 1 2 5 5 5 3 HEAT repeats Adaptin_N PF01602.20 KXX79775.1 - 0.022 13.3 0.0 1.7 7.1 0.0 2.5 2 1 1 3 3 3 0 Adaptin N terminal region DUF4704 PF15787.5 KXX79775.1 - 0.04 13.2 0.2 9.8 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) Cnd1 PF12717.7 KXX79775.1 - 0.07 13.2 0.0 2.6 8.1 0.0 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 KXX79775.1 - 0.073 13.0 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Tti2 PF10521.9 KXX79775.1 - 0.097 12.2 0.1 3.6 7.0 0.0 2.6 3 0 0 3 3 3 0 Tti2 family Vac14_Fab1_bd PF12755.7 KXX79775.1 - 0.18 12.5 0.0 13 6.4 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region BSP PF04450.12 KXX79776.1 - 2.7e-80 269.0 0.0 3.1e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 KXX79776.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 SprT-like family rRNA_processing PF08524.11 KXX79777.1 - 0.043 13.8 20.6 2.6 8.1 20.6 2.3 1 1 0 1 1 1 0 rRNA processing RhoGAP PF00620.27 KXX79778.1 - 5.7e-22 78.2 0.0 5.7e-22 78.2 0.0 2.6 2 1 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KXX79778.1 - 9.3e-14 51.4 18.6 3.6e-09 36.7 2.2 2.4 2 0 0 2 2 2 2 LIM domain zf-C3HC4_3 PF13920.6 KXX79778.1 - 0.012 15.5 2.0 0.012 15.5 2.0 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SCIMP PF15050.6 KXX79778.1 - 0.84 10.1 3.1 38 4.7 0.8 2.9 2 0 0 2 2 2 0 SCIMP protein GTP_EFTU PF00009.27 KXX79779.1 - 1.5e-66 223.7 0.1 2.1e-66 223.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXX79779.1 - 1.2e-32 112.2 0.0 6.2e-32 109.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KXX79779.1 - 2.4e-21 75.5 0.0 6.5e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXX79779.1 - 4.4e-13 49.4 0.1 1.8e-12 47.5 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXX79779.1 - 5e-12 45.7 0.0 1.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXX79779.1 - 0.00041 20.4 0.2 0.00095 19.2 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4210 PF13915.6 KXX79780.1 - 2.5e-32 111.3 0.2 5.7e-32 110.1 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KXX79780.1 - 8.2e-23 80.3 1.7 1.4e-22 79.6 1.0 1.8 2 0 0 2 2 2 1 Chromosome segregation during meiosis IPP-2 PF04979.14 KXX79780.1 - 0.45 11.3 3.2 0.42 11.4 0.2 2.4 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) Iso_dh PF00180.20 KXX79781.1 - 3.5e-98 329.0 0.0 4.3e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KXX79781.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Sec5 PF15469.6 KXX79782.1 - 5.5e-36 124.2 0.0 1.1e-35 123.2 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KXX79782.1 - 8.9e-05 22.5 0.3 0.0011 19.0 0.1 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Sec15 PF04091.12 KXX79782.1 - 0.0052 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF2415 PF10313.9 KXX79783.1 - 5.2e-15 55.1 0.0 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KXX79783.1 - 0.057 14.3 0.1 6.5 7.8 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79783.1 - 0.07 13.4 0.0 6.1 7.2 0.0 3.8 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 KXX79784.1 - 5.7e-268 890.1 16.0 6.5e-268 889.9 16.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXX79784.1 - 6.3e-15 54.8 4.6 5.1e-13 48.5 1.2 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KXX79784.1 - 0.00018 21.3 0.1 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3080 PF11279.8 KXX79784.1 - 0.0015 17.8 0.3 0.0024 17.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) StbA PF06406.11 KXX79784.1 - 0.0037 16.6 1.1 0.096 11.9 0.1 2.8 2 1 1 3 3 3 1 StbA protein Big_3_4 PF13754.6 KXX79784.1 - 0.051 13.3 0.0 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function PWI PF01480.17 KXX79786.1 - 4.2e-09 36.6 0.0 9.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KXX79786.1 - 2.8e-07 30.3 1.4 1.3e-06 28.2 0.2 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KXX79786.1 - 5.7e-05 22.9 3.3 0.0001 22.1 3.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXX79786.1 - 8.4e-05 22.5 4.2 0.00016 21.6 4.2 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KXX79786.1 - 0.00037 20.4 0.0 0.065 13.3 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF444 PF04285.12 KXX79786.1 - 0.027 13.6 5.6 0.045 12.8 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) RRM_occluded PF16842.5 KXX79786.1 - 0.027 14.3 0.0 0.088 12.7 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1330 PF07045.11 KXX79786.1 - 0.072 13.4 0.3 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) V_ATPase_I PF01496.19 KXX79786.1 - 0.099 10.5 5.3 0.13 10.2 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_3 PF08777.11 KXX79786.1 - 0.2 11.7 6.8 2.5 8.2 0.0 3.0 3 0 0 3 3 2 0 RNA binding motif zf-CCCH_2 PF14608.6 KXX79786.1 - 0.33 11.5 1.8 0.57 10.7 1.8 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PHM7_cyt PF14703.6 KXX79786.1 - 0.61 10.3 8.7 1 9.6 0.1 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter AAA_23 PF13476.6 KXX79786.1 - 1.3 9.5 8.2 0.61 10.6 5.7 1.7 2 0 0 2 2 2 0 AAA domain SRP68 PF16969.5 KXX79787.1 - 4.2e-204 679.7 0.2 4.7e-204 679.5 0.2 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 MTHFR PF02219.17 KXX79788.1 - 1.1e-112 376.0 0.0 1.8e-112 375.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PPR_2 PF13041.6 KXX79790.1 - 5.4e-14 52.1 5.8 2e-06 27.9 0.0 6.3 3 1 4 7 7 7 3 PPR repeat family PPR PF01535.20 KXX79790.1 - 1.9e-12 46.5 1.7 2.1e-05 24.5 0.0 6.8 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 KXX79790.1 - 8.2e-11 41.8 0.0 0.0032 17.5 0.0 4.0 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXX79790.1 - 7.8e-07 28.7 0.0 0.00056 19.6 0.0 3.5 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.6 KXX79790.1 - 7.6e-06 26.3 3.4 1.4 9.9 0.0 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX79790.1 - 0.00018 22.1 4.0 0.00075 20.1 0.0 3.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX79790.1 - 0.0064 17.0 0.0 13 6.4 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat ATP13 PF12921.7 KXX79790.1 - 0.036 13.9 0.0 0.23 11.3 0.0 2.3 3 0 0 3 3 2 0 Mitochondrial ATPase expression B12-binding_2 PF02607.17 KXX79790.1 - 0.037 14.5 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain TPR_2 PF07719.17 KXX79790.1 - 0.09 12.9 2.2 7.3 7.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX79790.1 - 0.16 11.8 2.3 13 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF676 PF05057.14 KXX79791.1 - 1.7e-42 145.5 0.0 2e-32 112.5 0.0 3.2 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KXX79791.1 - 0.044 13.7 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 KXX79791.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 KXX79791.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 2 0 0 2 2 2 0 Palmitoyl protein thioesterase zf-BED PF02892.15 KXX79792.1 - 0.2 11.7 2.7 0.24 11.5 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.18 KXX79792.1 - 6.9 6.9 13.6 0.29 11.3 7.9 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KXX79794.1 - 4.3e-10 40.1 0.0 1.3e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXX79794.1 - 3.8e-08 33.4 0.1 0.0004 20.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXX79794.1 - 6.1e-08 32.3 0.0 0.0009 19.5 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXX79794.1 - 1e-06 28.9 0.0 4.6e-06 26.8 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NACHT PF05729.12 KXX79794.1 - 1.1e-06 28.6 0.5 7.9e-06 25.9 0.1 2.5 2 1 0 2 2 2 1 NACHT domain Ank_4 PF13637.6 KXX79794.1 - 3.4e-06 27.5 0.0 8.9e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXX79794.1 - 0.0023 18.3 0.0 0.05 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.14 KXX79794.1 - 0.0039 16.7 0.0 0.0073 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_29 PF13555.6 KXX79794.1 - 0.054 13.2 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX79794.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXX79795.1 - 2.7e-17 63.4 0.0 8.3e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) W2 PF02020.18 KXX79795.1 - 0.029 14.5 0.8 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon DUF3333 PF11812.8 KXX79795.1 - 0.047 13.9 0.4 0.58 10.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) AAA_16 PF13191.6 KXX79795.1 - 0.068 13.6 0.3 0.28 11.5 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXX79795.1 - 0.076 13.3 1.7 0.46 10.8 0.1 2.8 1 1 1 3 3 3 0 AAA domain AAA_2 PF07724.14 KXX79795.1 - 0.094 12.8 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Solute_trans_a PF03619.16 KXX79796.1 - 1.2e-100 336.5 7.5 1.4e-100 336.2 7.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Ribosomal_L19e PF01280.20 KXX79796.1 - 0.26 11.4 0.6 0.56 10.3 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L19e Na_Ca_ex PF01699.24 KXX79797.1 - 1.1e-10 41.6 13.3 1.7e-09 37.8 13.3 2.0 1 1 0 1 1 1 1 Sodium/calcium exchanger protein Mid2 PF04478.12 KXX79797.1 - 0.19 11.6 2.7 0.13 12.1 0.6 1.7 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor IML1 PF12257.8 KXX79798.1 - 9.1e-104 346.6 0.1 3.6e-95 318.4 0.0 2.2 1 1 1 2 2 2 2 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KXX79798.1 - 5.2e-27 93.7 0.1 1.3e-26 92.4 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.21 KXX79799.1 - 1.3e-30 106.6 1.5 1.6e-30 106.4 1.5 1.0 1 0 0 1 1 1 1 Cation efflux family TM140 PF14985.6 KXX79799.1 - 0.022 14.3 0.2 0.022 14.3 0.2 1.5 2 0 0 2 2 2 0 TM140 protein family HhH-GPD PF00730.25 KXX79800.1 - 4.8e-06 27.0 0.0 8.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3413 PF11893.8 KXX79801.1 - 0.019 14.2 2.6 0.021 14.0 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Phage_holin_Dp1 PF16938.5 KXX79801.1 - 0.19 11.9 1.0 2.9 8.2 0.4 2.6 2 0 0 2 2 2 0 Putative phage holin Dp-1 UPF0016 PF01169.19 KXX79801.1 - 0.69 10.3 8.5 4.8 7.6 0.1 3.4 3 1 0 3 3 3 0 Uncharacterized protein family UPF0016 DUF3433 PF11915.8 KXX79801.1 - 9.6 6.8 8.8 5.1 7.6 3.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3433) adh_short_C2 PF13561.6 KXX79802.1 - 1.3e-55 188.5 0.0 1.8e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX79802.1 - 8.6e-44 149.3 0.0 1.1e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX79802.1 - 1.5e-10 41.3 0.0 2.1e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXX79802.1 - 0.0051 16.2 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 KXX79802.1 - 0.029 13.8 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Uricase PF01014.18 KXX79803.1 - 9.9e-80 265.2 0.9 1.5e-41 141.7 0.3 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 KXX79803.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Plasmid recombination enzyme RICTOR_N PF14664.6 KXX79804.1 - 2.2e-134 448.2 0.2 2.2e-134 448.2 0.2 2.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KXX79804.1 - 3.4e-38 129.6 0.1 1.1e-35 121.5 0.0 4.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KXX79804.1 - 6e-38 129.6 0.0 1.3e-35 122.0 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KXX79804.1 - 6.2e-30 103.3 0.9 6.3e-28 96.8 0.1 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KXX79804.1 - 6.8e-15 54.9 10.6 6.8e-15 54.9 10.6 2.6 2 0 0 2 2 2 1 Hr1 repeat SDA1 PF05285.12 KXX79804.1 - 0.0045 16.5 24.9 0.0045 16.5 24.9 2.8 3 0 0 3 3 3 1 SDA1 Arm PF00514.23 KXX79804.1 - 0.5 10.5 1.7 17 5.6 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF702 PF05142.12 KXX79804.1 - 1.5 9.3 8.0 0.29 11.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF5349 PF17298.2 KXX79804.1 - 2 8.1 11.2 4.7 6.9 11.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5349) FAR1 PF03101.15 KXX79805.1 - 1.8e-05 25.4 0.8 3.8e-05 24.3 0.8 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Matrilin_ccoil PF10393.9 KXX79805.1 - 0.027 14.3 1.9 0.44 10.4 0.6 2.4 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin CHDCT2 PF08074.11 KXX79805.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain AFT PF08731.11 KXX79805.1 - 0.53 10.7 2.9 0.39 11.1 0.2 1.9 2 0 0 2 2 2 0 Transcription factor AFT Spt20 PF12090.8 KXX79805.1 - 0.82 9.2 11.5 1.4 8.5 11.5 1.4 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 KXX79805.1 - 9.5 6.1 8.5 18 5.2 8.5 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TPR_1 PF00515.28 KXX79806.1 - 4.5e-17 61.1 10.9 2.4e-07 30.3 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXX79806.1 - 3e-15 55.0 6.2 6.1e-05 22.8 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXX79806.1 - 1.2e-09 38.3 0.3 3.8e-06 27.1 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXX79806.1 - 6.2e-09 35.4 6.3 9.2e-05 22.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXX79806.1 - 7e-08 32.0 2.4 7.3e-05 22.4 0.2 3.6 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.6 KXX79806.1 - 4.3e-06 27.0 2.3 0.62 10.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX79806.1 - 9.2e-06 25.3 0.3 0.0085 16.1 0.0 3.9 2 2 1 3 3 3 1 Tetratricopeptide repeat PB1 PF00564.24 KXX79806.1 - 9.8e-06 25.4 0.1 1.8e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.6 KXX79806.1 - 1.3e-05 25.2 1.9 0.056 13.6 0.0 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX79806.1 - 0.00015 22.4 0.1 0.096 13.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXX79806.1 - 0.0024 18.1 0.4 1 9.9 0.1 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX79806.1 - 0.003 18.2 0.1 1.3 10.0 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXX79806.1 - 0.015 15.2 0.0 4.9 7.2 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat HMA PF00403.26 KXX79807.1 - 1.4e-13 51.0 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KXX79807.1 - 4e-08 33.5 0.0 8.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.18 KXX79808.1 - 1.3e-39 135.3 0.0 2.3e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 CMAS PF02353.20 KXX79809.1 - 3.9e-62 210.0 0.1 4.8e-62 209.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXX79809.1 - 7.9e-10 38.8 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX79809.1 - 3.3e-09 37.3 0.0 6.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX79809.1 - 1.2e-08 35.5 0.0 2.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX79809.1 - 0.016 16.0 0.0 0.032 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXX79809.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KXX79809.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 KXX79809.1 - 0.21 11.1 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF498 PF04430.14 KXX79810.1 - 1.6e-21 76.4 0.0 2.4e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Ribosomal_L34e PF01199.18 KXX79811.1 - 1.2e-43 147.3 1.6 1.7e-43 146.9 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KXX79811.1 - 0.51 10.3 5.4 1.7 8.7 0.3 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Colicin_Pyocin PF01320.18 KXX79812.1 - 0.067 13.3 0.0 0.091 12.9 0.0 1.3 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein DEAD PF00270.29 KXX79813.1 - 9.1e-51 172.1 0.0 3.8e-49 166.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX79813.1 - 1.2e-31 109.3 0.1 3.3e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX79813.1 - 1.2e-05 25.4 0.0 5.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KXX79813.1 - 0.0067 15.3 0.1 0.54 9.0 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF5335 PF17269.2 KXX79813.1 - 0.066 13.1 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_22 PF13401.6 KXX79813.1 - 0.84 9.9 2.3 32 4.8 0.0 3.3 3 1 1 4 4 4 0 AAA domain Phos_pyr_kin PF08543.12 KXX79814.1 - 9.8e-79 264.2 1.2 6.2e-40 137.1 0.0 2.6 3 0 0 3 3 3 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KXX79814.1 - 7.9e-52 176.1 0.3 1.2e-51 175.6 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KXX79814.1 - 5.1e-06 26.0 0.1 8.5e-05 22.0 0.1 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF4867 PF16161.5 KXX79814.1 - 0.003 17.0 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4867) Carb_kinase PF01256.17 KXX79814.1 - 0.038 13.5 0.1 0.48 9.8 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate kinase AAR2 PF05282.11 KXX79815.1 - 6.5e-33 114.6 0.0 3.6e-22 79.2 0.0 2.1 1 1 1 2 2 2 2 AAR2 protein SSP160 PF06933.11 KXX79815.1 - 0.098 10.8 2.1 0.13 10.4 2.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FOXP-CC PF16159.5 KXX79816.1 - 0.12 13.0 0.3 0.31 11.7 0.3 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KXX79816.1 - 0.16 12.5 0.1 0.35 11.4 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1682 PF07946.14 KXX79816.1 - 0.24 10.5 2.3 0.33 10.1 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Mpv17_PMP22 PF04117.12 KXX79817.1 - 4.7e-09 36.4 5.5 2.7e-08 33.9 4.1 2.3 1 1 1 2 2 2 1 Mpv17 / PMP22 family EAP30 PF04157.16 KXX79818.1 - 1.3e-65 221.0 0.0 2.1e-65 220.3 0.0 1.2 1 1 0 1 1 1 1 EAP30/Vps36 family Hemerythrin PF01814.23 KXX79819.1 - 8.2e-08 32.9 13.8 9.9e-05 23.0 13.8 2.1 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Myb_DNA-bind_6 PF13921.6 KXX79821.1 - 2e-14 53.6 0.2 1.7e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXX79821.1 - 1.4e-12 47.6 0.1 2.2e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4085 PF13315.6 KXX79821.1 - 0.13 11.8 0.1 0.19 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) SNF2_N PF00176.23 KXX79822.1 - 1.7e-64 217.8 0.0 2.6e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX79822.1 - 5.5e-22 78.2 0.0 1.3e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX79822.1 - 0.0001 22.4 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit LON_substr_bdg PF02190.16 KXX79823.1 - 6e-23 81.8 0.0 9.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KXX79823.1 - 2.8e-10 39.8 7.8 6e-10 38.8 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX79823.1 - 2e-09 37.2 5.6 4e-09 36.2 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX79823.1 - 5.2e-09 36.0 6.8 1.3e-08 34.7 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXX79823.1 - 5.7e-08 32.5 6.5 1.1e-07 31.6 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX79823.1 - 2.2e-07 31.1 7.7 6.9e-07 29.5 7.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXX79823.1 - 6.8e-07 29.3 9.0 1.5e-06 28.3 9.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXX79823.1 - 7.6e-07 28.9 5.6 3.3e-06 26.8 5.8 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXX79823.1 - 1e-06 28.6 6.0 2.5e-06 27.3 6.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 KXX79823.1 - 0.00021 21.3 2.5 0.00044 20.3 2.5 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KXX79823.1 - 0.00044 20.4 0.0 0.00098 19.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXX79823.1 - 0.002 17.9 1.2 0.0051 16.6 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXX79823.1 - 0.012 15.4 7.4 0.047 13.5 7.4 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KXX79823.1 - 0.17 12.2 7.9 0.33 11.3 6.4 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-P11 PF03854.14 KXX79823.1 - 0.32 10.7 6.8 0.17 11.6 4.2 1.8 2 0 0 2 2 2 0 P-11 zinc finger efThoc1 PF11957.8 KXX79825.1 - 7.5e-143 476.7 0.5 9.9e-143 476.3 0.5 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KXX79825.1 - 2.5e-26 92.5 0.0 4.4e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase HlyD_D4 PF16572.5 KXX79825.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Aquarius_N PF16399.5 KXX79826.1 - 0 1137.1 0.0 0 1136.7 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KXX79826.1 - 6.1e-22 78.2 0.0 9.7e-21 74.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.6 KXX79826.1 - 3.8e-21 76.0 0.0 1.4e-20 74.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXX79826.1 - 2e-08 34.2 0.0 0.00093 19.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KXX79826.1 - 3.4e-06 27.2 0.0 7.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXX79826.1 - 1.7e-05 25.2 0.0 4.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX79826.1 - 0.00057 20.3 0.0 0.0031 17.9 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXX79826.1 - 0.0018 18.7 0.0 0.0054 17.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KXX79826.1 - 0.0038 16.6 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Viral_helicase1 PF01443.18 KXX79826.1 - 0.0096 15.7 0.1 0.54 10.0 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KXX79826.1 - 0.012 15.5 0.7 0.098 12.5 0.1 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KXX79826.1 - 0.022 15.0 0.8 0.42 10.9 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 KXX79826.1 - 0.06 12.9 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXX79826.1 - 0.062 12.5 1.2 0.097 11.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KXX79826.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase_2 PF01637.18 KXX79826.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KXX79826.1 - 0.18 12.2 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RecA PF00154.21 KXX79826.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Parvo_NS1 PF01057.17 KXX79826.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HSA PF07529.13 KXX79827.1 - 1e-12 48.2 0.1 1e-12 48.2 0.1 3.6 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 KXX79827.1 - 1.1e-12 48.1 0.1 3.6e-12 46.4 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXX79827.1 - 6.9e-05 23.0 0.3 0.00017 21.7 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2656 PF10847.8 KXX79828.1 - 0.063 13.4 2.2 0.09 12.9 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) TFIIA PF03153.13 KXX79828.1 - 0.27 11.2 20.6 0.29 11.1 20.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1631 PF07793.11 KXX79828.1 - 0.71 8.2 19.3 0.81 8.0 19.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Neur_chan_memb PF02932.16 KXX79828.1 - 1.8 8.5 6.8 2.5 8.1 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 KXX79828.1 - 2.1 7.9 15.6 2.8 7.5 15.6 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 KXX79828.1 - 4.5 7.2 11.0 5.5 6.9 11.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 KXX79828.1 - 5.5 5.5 9.1 6.6 5.3 9.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 KXX79829.1 - 6e-12 45.9 0.1 1 10.3 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79829.1 - 0.16 12.3 0.0 90 3.5 0.0 3.8 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain INSIG PF07281.12 KXX79830.1 - 1.7e-84 282.7 2.9 2.3e-84 282.3 2.9 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Alpha-amylase PF00128.24 KXX79831.1 - 6.9e-118 394.1 0.7 8.7e-118 393.7 0.1 1.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXX79831.1 - 0.00062 19.8 0.0 0.0021 18.1 0.0 2.0 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KXX79831.1 - 0.039 13.0 0.1 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Spo7 PF03907.13 KXX79831.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Spo7-like protein DUF4993 PF16384.5 KXX79831.1 - 0.1 11.6 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function G-patch_2 PF12656.7 KXX79832.1 - 1.7e-12 47.2 1.9 5.6e-12 45.6 0.1 2.7 2 0 0 2 2 2 1 G-patch domain Pro-kuma_activ PF09286.11 KXX79833.1 - 1.8e-44 151.5 0.0 3e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXX79833.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Subtilase family DUF3678 PF12435.8 KXX79833.1 - 0.038 13.4 1.1 0.085 12.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Asp PF00026.23 KXX79834.1 - 2.3e-56 191.5 1.4 2.7e-56 191.3 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX79834.1 - 7.7e-13 49.1 1.3 2.2e-10 41.1 0.1 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXX79834.1 - 0.00029 21.4 0.0 0.59 10.8 0.0 2.8 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KXX79834.1 - 0.013 16.1 0.0 10 6.8 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1966 PF09260.11 KXX79835.1 - 3.2e-15 56.2 0.1 7.3e-15 55.0 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KXX79835.1 - 5.4e-05 22.9 0.0 8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain MFS_1 PF07690.16 KXX79836.1 - 2.3e-24 86.0 23.6 2.3e-24 86.0 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX79836.1 - 0.0013 17.3 3.5 0.0023 16.5 3.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Alpha-amylase PF00128.24 KXX79837.1 - 8.1e-30 104.5 0.6 2.7e-28 99.5 0.1 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain COesterase PF00135.28 KXX79838.1 - 3.3e-80 270.4 0.0 4.9e-80 269.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX79838.1 - 0.0092 15.9 0.3 0.026 14.4 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX79838.1 - 0.054 13.0 0.3 0.27 10.7 0.3 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Iron_traffic PF04362.14 KXX79838.1 - 0.13 12.0 0.0 27 4.5 0.0 2.8 3 0 0 3 3 3 0 Bacterial Fe(2+) trafficking 2OG-FeII_Oxy_3 PF13640.6 KXX79840.1 - 4.3e-10 40.3 0.0 7.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAD_binding_10 PF13460.6 KXX79842.1 - 2.1e-17 63.6 0.0 3.4e-17 63.0 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX79842.1 - 1.9e-06 27.6 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXX79842.1 - 0.003 17.1 0.0 0.015 14.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAC2 PF09754.9 KXX79842.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.6 1 1 0 1 1 1 0 PAC2 family Thioredoxin_6 PF13848.6 KXX79843.1 - 7.6e-16 58.6 0.0 2.3e-14 53.7 0.0 2.1 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 KXX79843.1 - 4.1e-07 29.9 0.0 1.8e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin OST3_OST6 PF04756.13 KXX79843.1 - 0.024 14.0 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DDE_Tnp_IS240 PF13610.6 KXX79843.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 DDE domain Hist_deacetyl PF00850.19 KXX79844.1 - 5.9e-80 269.0 0.1 1.1e-79 268.1 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Abhydrolase_4 PF08386.10 KXX79845.1 - 2.1e-18 66.3 0.0 4.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXX79845.1 - 5.7e-14 52.4 0.2 1.4e-13 51.1 0.3 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold ThrE PF06738.12 KXX79846.1 - 1.1e-69 234.5 9.2 4.7e-68 229.1 2.8 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXX79846.1 - 1.5e-05 25.1 25.4 4.3e-05 23.7 1.6 3.4 3 0 0 3 3 3 3 Threonine/Serine exporter, ThrE SR-25 PF10500.9 KXX79846.1 - 0.25 10.9 5.2 0.59 9.7 5.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_A4 PF01828.17 KXX79847.1 - 3.9e-66 222.5 5.7 4.7e-66 222.2 5.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family RNase_PH PF01138.21 KXX79848.1 - 6.1e-36 123.8 0.0 9.6e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 JAB PF01398.21 KXX79851.1 - 1.4e-32 112.1 0.0 2.7e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXX79851.1 - 2.9e-12 47.0 0.6 5.6e-12 46.1 0.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KXX79851.1 - 1.6e-07 31.1 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 KXX79851.1 - 0.073 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Vta1 PF04652.16 KXX79852.1 - 2e-52 177.0 9.0 2e-52 177.0 9.0 1.4 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KXX79852.1 - 1.6e-17 62.9 1.4 1.9e-17 62.6 0.1 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain Thioredoxin PF00085.20 KXX79853.1 - 3e-31 107.5 0.1 1e-24 86.5 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KXX79853.1 - 2.5e-06 27.5 0.0 0.00028 20.9 0.0 3.2 2 2 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXX79853.1 - 3.4e-06 26.6 0.1 2.9e-05 23.6 0.0 2.3 1 1 2 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXX79853.1 - 3.6e-06 27.4 0.8 0.037 14.5 0.1 2.6 1 1 1 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KXX79853.1 - 0.0018 18.2 0.1 0.043 13.7 0.0 2.5 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXX79853.1 - 0.0075 16.6 0.1 3 8.2 0.0 4.1 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXX79853.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 KXX79853.1 - 0.026 14.3 0.0 0.026 14.3 0.0 3.8 3 1 1 4 4 4 0 F plasmid transfer operon protein HyaE PF07449.11 KXX79853.1 - 0.052 13.5 0.0 0.56 10.2 0.0 2.6 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE p450 PF00067.22 KXX79854.1 - 1.8e-68 231.4 0.0 2.1e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amino_oxidase PF01593.24 KXX79855.1 - 1.8e-55 189.1 0.0 2.2e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX79855.1 - 3.4e-09 36.8 0.0 2.9e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX79855.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KXX79855.1 - 0.021 14.4 0.0 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX79855.1 - 0.023 13.4 0.2 0.036 12.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KXX79855.1 - 0.036 13.3 0.1 0.057 12.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KXX79855.1 - 0.036 13.3 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KXX79855.1 - 0.04 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX79855.1 - 0.086 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YopE_N PF09020.10 KXX79856.1 - 0.12 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 YopE, N terminal Abhydrolase_4 PF08386.10 KXX79857.1 - 8.9e-22 77.2 0.0 1.7e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXX79857.1 - 8.5e-14 51.8 0.1 1.2e-11 44.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3224 PF11528.8 KXX79857.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) Gcd10p PF04189.13 KXX79858.1 - 1.1e-120 402.3 0.0 4.2e-114 380.7 0.0 2.1 2 0 0 2 2 2 2 Gcd10p family MPDZ_u10 PF16667.5 KXX79858.1 - 0.056 14.4 0.2 0.16 12.9 0.2 1.8 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein Glyco_hydro_76 PF03663.14 KXX79859.1 - 7.5e-148 492.9 0.6 1e-147 492.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF3426 PF11906.8 KXX79860.1 - 0.089 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) P21-Arc PF04062.14 KXX79861.1 - 4.9e-70 235.1 0.0 6.1e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit BTRD1 PF17660.1 KXX79862.1 - 2.9e-117 382.4 26.6 2.2e-25 88.2 1.1 5.1 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 DUF3884 PF13024.6 KXX79862.1 - 0.0081 15.7 0.2 25 4.5 0.0 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3884) HET PF06985.11 KXX79863.1 - 6.6e-15 55.7 0.1 2.9e-12 47.1 0.0 2.6 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) Terpene_synth_C PF03936.16 KXX79864.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain FAD-oxidase_C PF02913.19 KXX79865.1 - 1.3e-59 201.9 0.0 2e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXX79865.1 - 2.1e-38 131.2 0.0 4.1e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXX79866.1 - 6.4e-89 298.9 0.1 7.4e-89 298.7 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX79866.1 - 8e-07 29.2 0.0 3.3e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX79866.1 - 1.2e-05 25.1 0.0 0.00022 20.9 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KXX79866.1 - 1.6e-05 24.2 0.1 1.6e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXX79866.1 - 6.5e-05 22.3 0.1 0.00054 19.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX79866.1 - 8.7e-05 21.4 1.3 0.0019 17.0 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXX79866.1 - 9e-05 21.9 0.1 0.00034 20.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KXX79866.1 - 0.00055 19.4 0.0 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX79866.1 - 0.001 18.4 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXX79866.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX79866.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXX79866.1 - 0.43 9.6 1.3 0.53 9.3 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Sugar_tr PF00083.24 KXX79867.1 - 7.9e-104 348.0 31.6 1e-103 347.7 31.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX79867.1 - 2.1e-25 89.4 35.7 3.2e-22 79.0 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HEPN_SAV_6107 PF18726.1 KXX79868.1 - 0.08 13.4 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 SAV_6107-like HEPN PEPcase_2 PF14010.6 KXX79868.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Methyltransf_23 PF13489.6 KXX79869.1 - 2.5e-25 89.2 0.0 3.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX79869.1 - 3e-11 43.9 0.0 7.9e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX79869.1 - 2.3e-08 34.5 0.0 5.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX79869.1 - 2.6e-08 34.5 0.0 1.9e-07 31.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX79869.1 - 6.3e-06 26.1 0.0 6.9e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXX79869.1 - 0.00099 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KXX79869.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KXX79869.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Oxysterol_BP PF01237.18 KXX79870.1 - 6.1e-50 170.1 0.0 2.5e-43 148.4 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein DUF835 PF05763.12 KXX79872.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF835) SAD_SRA PF02182.17 KXX79873.1 - 1.1e-34 119.4 0.1 1.7e-34 118.8 0.1 1.3 1 0 0 1 1 1 1 SAD/SRA domain Ank_5 PF13857.6 KXX79874.1 - 7.1e-14 51.7 0.1 1.6e-06 28.3 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX79874.1 - 9.4e-09 35.6 0.8 0.35 11.5 0.0 4.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX79874.1 - 5.4e-08 33.3 0.0 0.0021 18.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX79874.1 - 0.00016 22.0 1.2 2.2 8.9 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXX79874.1 - 0.0057 17.1 4.1 0.63 10.8 0.0 4.8 5 1 0 5 5 5 1 Ankyrin repeat DUF3678 PF12435.8 KXX79874.1 - 0.011 15.1 1.8 0.022 14.1 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) HypA PF01155.19 KXX79876.1 - 0.79 9.8 2.4 1.7 8.7 0.0 2.4 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 KXX79876.1 - 4.6 7.2 5.7 7 6.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain GRDP-like PF07173.12 KXX79877.1 - 2.2e-18 67.3 10.2 2.4e-14 54.2 0.3 4.0 3 1 1 4 4 4 3 Glycine-rich domain-containing protein-like Use1 PF09753.9 KXX79877.1 - 2.5 7.7 10.6 4 7.1 10.6 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DJ-1_PfpI PF01965.24 KXX79880.1 - 2.6e-16 59.9 0.0 3.2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Pyr_redox_2 PF07992.14 KXX79881.1 - 8e-14 51.5 0.0 2.2e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX79881.1 - 0.003 17.6 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KXX79881.1 - 0.0078 15.8 1.3 0.021 14.4 0.3 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXX79881.1 - 0.18 10.9 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXX79881.1 - 0.21 10.8 0.0 0.45 9.7 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 KXX79882.1 - 1.9e-13 50.9 6.7 3.4e-13 50.0 6.7 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXX79882.1 - 0.0036 16.8 0.9 0.011 15.3 0.9 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1100 PF06500.11 KXX79883.1 - 1.5e-11 43.8 0.0 2.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.20 KXX79883.1 - 1.2e-08 34.9 0.0 4.9e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KXX79883.1 - 6.1e-08 32.6 0.0 6.4e-06 26.0 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX79883.1 - 5.7e-07 30.4 3.5 5.7e-07 30.4 3.5 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KXX79883.1 - 6.1e-07 29.3 0.0 8.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXX79883.1 - 1.6e-05 24.5 0.2 4.1e-05 23.2 0.2 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXX79883.1 - 5.4e-05 23.1 0.0 9.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXX79883.1 - 0.00029 20.2 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXX79883.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_7 PF12715.7 KXX79883.1 - 0.069 12.4 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 Abhydrolase family Esterase_phd PF10503.9 KXX79883.1 - 0.083 12.4 0.0 0.45 10.0 0.0 2.2 2 1 0 2 2 2 0 Esterase PHB depolymerase DLH PF01738.18 KXX79883.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family FAD_binding_4 PF01565.23 KXX79885.1 - 3.3e-22 78.7 1.9 5.4e-21 74.8 2.1 2.4 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXX79885.1 - 0.00027 21.0 0.1 0.0006 19.9 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Selenoprotein_S PF06936.11 KXX79885.1 - 0.066 13.0 0.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) RE_TaqI PF09573.10 KXX79886.1 - 0.19 11.5 0.1 0.29 10.9 0.1 1.1 1 0 0 1 1 1 0 TaqI restriction endonuclease Patatin PF01734.22 KXX79887.1 - 1.2e-07 32.2 0.1 1.7e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase NR_Repeat PF14046.6 KXX79888.1 - 0.032 14.4 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 Nuclear receptor repeat ADH_zinc_N PF00107.26 KXX79889.1 - 3.5e-20 72.3 0.0 4.8e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXX79889.1 - 1.7e-15 56.8 0.0 3.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXX79889.1 - 1.7e-07 32.4 0.0 2.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_S8 PF00082.22 KXX79891.1 - 1e-14 54.5 0.0 2.3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 KXX79891.1 - 9.5e-09 35.7 0.5 0.0031 18.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX79891.1 - 7.8e-05 23.2 0.0 0.059 14.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX79891.1 - 0.00056 20.2 0.0 3.1 8.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXX79891.1 - 0.0019 18.6 0.0 2.2 8.9 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KXX79891.1 - 0.019 15.3 0.6 9 6.7 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) RRM_3 PF08777.11 KXX79891.1 - 0.12 12.4 0.5 1.8 8.6 0.1 2.8 3 0 0 3 3 3 0 RNA binding motif Jag_N PF14804.6 KXX79891.1 - 1.4 9.3 3.2 8.1 6.9 0.0 3.3 3 0 0 3 3 3 0 Jag N-terminus Sigma70_ner PF04546.13 KXX79891.1 - 8.5 6.2 13.6 3 7.7 0.2 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region p450 PF00067.22 KXX79892.1 - 3.5e-65 220.6 0.0 4.3e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTV_P6 PF06706.11 KXX79892.1 - 0.068 12.9 0.4 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein DIT1_PvcA PF05141.12 KXX79893.1 - 7.1e-99 330.7 0.0 8.8e-99 330.4 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein adh_short_C2 PF13561.6 KXX79894.1 - 2.2e-48 164.9 0.6 2.9e-48 164.5 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX79894.1 - 8.4e-44 149.4 4.0 9.9e-44 149.1 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX79894.1 - 8.7e-05 22.5 0.7 0.00011 22.2 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX79894.1 - 0.0022 17.5 0.3 0.0066 15.9 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX79894.1 - 0.016 15.1 0.8 0.022 14.7 0.8 1.2 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 KXX79894.1 - 0.045 13.6 1.1 0.082 12.8 1.1 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXX79894.1 - 0.056 14.2 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KXX79895.1 - 5.3e-40 137.4 49.5 7.5e-39 133.6 24.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX79895.1 - 4.8e-14 52.1 7.3 4.8e-14 52.1 7.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter PTR2 PF00854.21 KXX79895.1 - 0.0016 17.4 0.2 0.0016 17.4 0.2 1.7 2 0 0 2 2 2 1 POT family OATP PF03137.20 KXX79895.1 - 0.25 9.6 11.4 0.2 9.9 2.1 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 KXX79895.1 - 5.3 5.2 9.3 2.7 6.1 1.0 2.2 2 0 0 2 2 2 0 BT1 family CFEM PF05730.11 KXX79897.1 - 1.9e-30 104.7 87.9 6.1e-10 39.1 9.8 7.9 4 4 4 8 8 8 4 CFEM domain Patatin PF01734.22 KXX79898.1 - 1.3e-12 48.4 0.1 2.6e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_UBOX PF13445.6 KXX79898.1 - 0.0018 18.3 1.2 0.0061 16.6 1.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXX79898.1 - 0.05 13.8 1.6 0.15 12.2 1.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KXX79898.1 - 0.076 12.9 4.6 0.29 11.0 4.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX79898.1 - 0.1 12.6 7.4 0.057 13.4 4.6 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KXX79898.1 - 1 9.7 7.1 5.2 7.5 7.1 2.3 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KXX79898.1 - 5.8 6.9 7.2 0.42 10.5 1.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXX79898.1 - 9.9 6.1 8.7 1.4 8.8 4.0 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 ABC_tran PF00005.27 KXX79899.1 - 0.0028 18.2 0.0 0.005 17.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 KXX79899.1 - 0.0093 16.0 0.0 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX79899.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KXX79899.1 - 0.027 14.7 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXX79899.1 - 0.029 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXX79899.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KXX79899.1 - 0.071 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KXX79899.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CEBP_ZZ PF16366.5 KXX79899.1 - 0.81 10.0 5.4 1.5 9.1 5.4 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 KXX79899.1 - 0.89 9.8 7.8 1.4 9.1 7.8 1.3 1 0 0 1 1 1 0 B-box zinc finger DUF3176 PF11374.8 KXX79900.1 - 6.4e-19 68.1 0.0 9.7e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF5451 PF17532.2 KXX79900.1 - 0.023 15.0 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5451) DUF3237 PF11578.8 KXX79902.1 - 4.4e-29 101.3 0.4 1.5e-23 83.3 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) Zn_clus PF00172.18 KXX79903.1 - 1e-09 38.3 9.4 1.7e-09 37.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX79903.1 - 7.8e-07 28.4 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Kinesin PF00225.23 KXX79904.1 - 2e-59 201.2 0.0 3e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXX79904.1 - 2.2e-08 34.2 0.0 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Pectate_lyase PF03211.13 KXX79905.1 - 5.5e-82 274.2 5.8 6.4e-82 274.0 5.8 1.0 1 0 0 1 1 1 1 Pectate lyase TauD PF02668.16 KXX79906.1 - 1.3e-44 153.0 0.1 1.8e-44 152.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SIR2 PF02146.17 KXX79907.1 - 3.1e-25 89.1 0.5 8.7e-18 64.9 0.0 2.9 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KXX79907.1 - 0.019 14.7 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TauD PF02668.16 KXX79907.1 - 0.099 12.4 0.0 1.7 8.4 0.0 2.0 1 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.19 KXX79909.1 - 3.9e-16 59.2 0.2 8.3e-15 54.9 0.2 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX79909.1 - 1.2e-05 25.4 0.2 2.7e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX79909.1 - 1.9e-05 24.1 0.1 0.033 13.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX79909.1 - 0.0006 20.3 0.1 0.15 12.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXX79909.1 - 0.017 14.2 0.0 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 KXX79909.1 - 0.02 14.5 0.4 0.052 13.1 0.3 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX79909.1 - 0.028 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXX79909.1 - 0.06 12.6 0.0 1 8.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 KXX79910.1 - 3.6e-86 283.8 0.0 2.3e-12 47.3 0.0 10.9 4 3 6 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX79910.1 - 8.1e-64 211.2 6.6 7.5e-09 36.0 0.1 16.3 9 3 7 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX79910.1 - 1.1e-53 178.6 26.2 1.9e-05 24.8 0.0 16.9 7 6 13 20 20 20 16 Ankyrin repeats (many copies) Ank PF00023.30 KXX79910.1 - 3.8e-53 175.7 29.7 0.0016 18.8 0.0 20.1 21 0 0 21 21 21 14 Ankyrin repeat Ank_3 PF13606.6 KXX79910.1 - 1.5e-51 166.3 20.3 0.0021 18.4 0.0 20.6 21 1 0 21 21 21 13 Ankyrin repeat ZZ PF00569.17 KXX79910.1 - 2.3e-07 30.5 8.9 4.6e-07 29.5 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KXX79910.1 - 0.0079 16.5 8.8 0.016 15.5 8.8 1.5 1 0 0 1 1 1 1 C1 domain Cyt-b5 PF00173.28 KXX79912.1 - 2e-12 47.1 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HET PF06985.11 KXX79913.1 - 1.5e-19 70.8 0.0 1.1e-18 68.0 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4033 PF13225.6 KXX79913.1 - 0.0071 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) DUF1295 PF06966.12 KXX79914.1 - 1.9e-37 129.0 7.9 2.5e-37 128.6 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2830 PF11125.8 KXX79915.1 - 1.5 8.8 3.9 0.78 9.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) DUF4149 PF13664.6 KXX79916.1 - 2.8e-24 85.4 2.3 2.8e-24 85.4 2.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) ECF_trnsprt PF12822.7 KXX79916.1 - 1.6 8.8 9.4 0.36 10.9 5.5 1.7 2 1 0 2 2 2 0 ECF transporter, substrate-specific component Ku PF02735.16 KXX79917.1 - 4e-34 118.1 0.0 6.7e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KXX79917.1 - 1.5e-33 115.5 0.0 3.4e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KXX79917.1 - 6.6e-16 58.7 0.0 1.1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KXX79917.1 - 3e-05 24.3 0.1 8e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 KXX79917.1 - 0.064 14.0 1.3 0.2 12.4 0.0 2.5 3 1 0 3 3 3 0 Ku70/Ku80 C-terminal arm DUF2408 PF10303.9 KXX79917.1 - 0.13 12.8 0.5 0.36 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF374 PF04028.13 KXX79918.1 - 0.097 12.2 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Pam16 PF03656.13 KXX79919.1 - 1.4e-05 25.1 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KXX79919.1 - 3.5e-05 23.8 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Glycos_transf_1 PF00534.20 KXX79920.1 - 2.7e-27 95.4 0.0 4e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXX79920.1 - 2e-23 83.3 0.1 3.2e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXX79920.1 - 7.4e-10 39.1 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 PIGA PF08288.12 KXX79920.1 - 2.3e-05 24.9 1.1 0.00016 22.2 0.2 2.6 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_2 PF13524.6 KXX79920.1 - 0.00018 21.8 0.0 0.00041 20.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 SKG6 PF08693.10 KXX79921.1 - 8.4e-09 34.7 4.6 1.4e-08 34.0 4.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KXX79921.1 - 0.00042 20.1 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) VSP PF03302.13 KXX79921.1 - 0.00045 19.2 0.0 0.00052 19.0 0.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein stn_TNFRSF12A PF12191.8 KXX79921.1 - 0.0033 17.6 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Epiglycanin_C PF14654.6 KXX79921.1 - 0.013 15.6 0.3 0.024 14.7 0.3 1.5 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF4381 PF14316.6 KXX79921.1 - 0.15 12.3 0.1 0.2 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KXX79921.1 - 0.15 12.9 0.0 0.2 12.5 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.7 KXX79923.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like CENP-X PF09415.10 KXX79924.1 - 2.4e-25 88.6 0.2 2.4e-25 88.6 0.2 2.2 2 1 0 2 2 2 1 CENP-S associating Centromere protein X RskA PF10099.9 KXX79924.1 - 0.01 16.2 5.1 0.033 14.5 3.1 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TRAP_alpha PF03896.16 KXX79924.1 - 0.059 12.6 2.3 0.077 12.2 2.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SPX PF03105.19 KXX79924.1 - 0.32 10.9 2.9 0.38 10.6 2.9 1.0 1 0 0 1 1 1 0 SPX domain ORC6 PF05460.13 KXX79924.1 - 9.9 5.3 6.2 17 4.6 6.2 1.5 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mito_carr PF00153.27 KXX79925.1 - 3.3e-68 225.7 4.7 1.4e-24 85.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 KXX79926.1 - 1.3e-08 35.0 0.0 2.5e-07 31.0 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX79926.1 - 2.3e-08 34.1 0.0 0.00072 19.5 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX79926.1 - 3.1e-08 33.9 0.0 8.7e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX79926.1 - 0.00016 21.6 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KXX79926.1 - 0.00071 19.7 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 KXX79926.1 - 0.034 14.8 0.1 3.2 8.5 0.1 2.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXX79926.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.6 KXX79927.1 - 2.4e-42 145.1 0.0 3.4e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX79927.1 - 1.5e-41 142.0 0.0 2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX79927.1 - 4.7e-07 29.9 0.0 7.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXX79927.1 - 0.00045 19.4 0.0 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXX79927.1 - 0.0084 16.0 0.0 0.085 12.7 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX79927.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX79927.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ribosomal_S25 PF03297.15 KXX79928.1 - 8.9e-39 131.8 5.2 9.7e-39 131.6 5.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.12 KXX79928.1 - 0.0018 17.7 0.3 0.0033 16.9 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.6 KXX79928.1 - 0.0021 17.6 0.2 0.0035 16.9 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 KXX79928.1 - 0.0066 16.2 0.1 0.0092 15.7 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KXX79928.1 - 0.014 15.7 0.1 0.02 15.2 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 KXX79928.1 - 0.036 13.9 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 KXX79928.1 - 0.058 13.3 0.1 0.078 12.9 0.1 1.2 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 KXX79928.1 - 0.072 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_S7 PF00177.21 KXX79929.1 - 1.6e-37 128.4 1.8 2.1e-37 128.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e p450 PF00067.22 KXX79931.1 - 1.1e-30 106.8 0.0 1.4e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tannase PF07519.11 KXX79932.1 - 4.4e-90 302.8 0.0 5e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KXX79932.1 - 0.00053 19.5 0.0 0.6 9.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXX79932.1 - 0.0049 16.2 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 SpoVS PF04232.12 KXX79932.1 - 0.018 14.7 1.4 0.02 14.6 0.1 1.7 2 0 0 2 2 2 0 Stage V sporulation protein S (SpoVS) Abhydrolase_1 PF00561.20 KXX79932.1 - 0.032 13.9 0.2 0.088 12.4 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Zn_clus PF00172.18 KXX79933.1 - 1.1e-05 25.5 3.5 1.9e-05 24.7 3.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Stb3 PF10330.9 KXX79934.1 - 3.7e-37 126.2 0.0 5.7e-37 125.6 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein HET PF06985.11 KXX79935.1 - 2.6e-30 105.7 0.0 4.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3875 PF12991.7 KXX79935.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) Topoisom_bac PF01131.20 KXX79936.1 - 5.9e-107 358.2 0.0 2.9e-101 339.5 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KXX79936.1 - 7.6e-20 71.1 0.0 1.5e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain EF-hand_4 PF12763.7 KXX79937.1 - 5.1e-34 116.3 0.0 2e-13 50.2 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KXX79937.1 - 8e-12 45.4 0.1 5.4e-07 30.0 0.2 4.9 4 1 0 4 4 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KXX79937.1 - 5.1e-09 35.1 0.5 0.29 10.8 0.5 5.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KXX79937.1 - 7.5e-07 28.6 0.6 0.099 12.6 0.3 4.9 5 0 0 5 5 4 1 EF-hand domain UBA PF00627.31 KXX79937.1 - 0.00014 21.7 0.1 0.00043 20.1 0.0 1.8 2 0 0 2 2 1 1 UBA/TS-N domain DUF812 PF05667.11 KXX79937.1 - 0.00017 20.7 14.9 0.00017 20.7 14.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Spc7 PF08317.11 KXX79937.1 - 0.0057 15.6 33.0 0.067 12.1 18.6 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 KXX79937.1 - 0.0097 16.1 15.4 0.0097 16.1 15.4 3.8 4 1 1 5 5 2 2 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 KXX79937.1 - 0.017 16.0 9.9 0.017 16.0 9.9 3.6 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain EF-hand_8 PF13833.6 KXX79937.1 - 0.027 14.3 0.0 15 5.5 0.0 3.7 3 1 1 4 4 4 0 EF-hand domain pair CENP-F_leu_zip PF10473.9 KXX79937.1 - 0.031 14.3 30.8 0.068 13.2 10.9 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KXX79937.1 - 0.039 13.3 32.3 0.48 9.8 15.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KXX79937.1 - 0.049 13.7 36.2 0.39 10.8 20.9 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KXX79937.1 - 0.059 13.4 36.1 0.4 10.8 9.3 3.8 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KXX79937.1 - 0.13 12.3 15.6 0.22 11.6 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 KXX79937.1 - 0.19 9.2 28.6 0.27 8.7 28.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AIP3 PF03915.13 KXX79937.1 - 0.19 10.8 15.3 0.39 9.7 15.3 1.5 1 0 0 1 1 1 0 Actin interacting protein 3 Scaffolding_pro PF11418.8 KXX79937.1 - 0.37 11.4 8.2 2.4 8.8 0.1 3.0 1 1 1 3 3 2 0 Phi29 scaffolding protein TMF_TATA_bd PF12325.8 KXX79937.1 - 0.37 11.0 26.3 0.15 12.3 2.7 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.6 KXX79937.1 - 0.79 9.7 37.1 2.3 8.3 14.4 3.0 1 1 1 2 2 2 0 FlxA-like protein CALCOCO1 PF07888.11 KXX79937.1 - 0.8 8.5 27.7 1.3 7.8 27.7 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TolA_bind_tri PF16331.5 KXX79937.1 - 0.89 9.7 33.8 2.3 8.3 1.3 4.4 1 1 3 4 4 4 0 TolA binding protein trimerisation Cep57_MT_bd PF06657.13 KXX79937.1 - 0.91 10.0 20.1 1.3 9.6 3.5 3.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SYCE1 PF15233.6 KXX79937.1 - 0.91 9.6 23.5 2.4 8.2 1.2 3.0 1 1 2 3 3 3 0 Synaptonemal complex central element protein 1 Golgin_A5 PF09787.9 KXX79937.1 - 1.7 8.0 29.6 0.57 9.6 22.6 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 APG6_N PF17675.1 KXX79937.1 - 1.8 9.1 35.0 32 5.1 6.8 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KXX79937.1 - 1.8 8.8 29.8 0.91 9.7 16.7 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 KXX79937.1 - 1.9 8.9 27.0 8.6 6.8 26.6 2.0 1 1 0 1 1 1 0 Fez1 Csm1_N PF18504.1 KXX79937.1 - 2.1 8.7 27.5 0.079 13.3 1.7 4.2 3 1 1 4 4 4 0 Csm1 N-terminal domain Filament PF00038.21 KXX79937.1 - 2.2 7.8 29.6 1.7 8.2 13.7 2.2 1 1 1 2 2 2 0 Intermediate filament protein Exonuc_VII_L PF02601.15 KXX79937.1 - 2.3 7.7 17.4 4.4 6.8 17.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit HrpB7 PF09486.10 KXX79937.1 - 3.2 8.1 17.9 12 6.3 17.6 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FUSC PF04632.12 KXX79937.1 - 3.5 6.0 7.2 5.9 5.3 7.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.14 KXX79937.1 - 4.1 7.2 23.1 8.2 6.2 18.4 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Tup_N PF08581.10 KXX79937.1 - 5 7.5 14.7 0.91 9.9 3.5 2.9 1 1 1 2 2 2 0 Tup N-terminal SOGA PF11365.8 KXX79937.1 - 5.3 8.2 16.3 15 6.8 11.2 3.4 2 1 1 3 3 3 0 Protein SOGA ZapB PF06005.12 KXX79937.1 - 6 7.4 34.6 0.86 10.1 7.1 4.3 2 1 2 4 4 4 0 Cell division protein ZapB PI3K_P85_iSH2 PF16454.5 KXX79937.1 - 6.3 6.4 24.6 1.4 8.5 1.2 3.0 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain EzrA PF06160.12 KXX79937.1 - 6.5 4.8 24.9 1.6 6.8 20.7 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA COG2 PF06148.11 KXX79937.1 - 6.7 6.8 14.6 0.22 11.6 3.8 2.6 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 KXX79937.1 - 8.7 5.6 33.1 8.9 5.5 12.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Baculo_F PF12259.8 KXX79937.1 - 9.5 4.6 8.6 14 4.1 8.6 1.1 1 0 0 1 1 1 0 Baculovirus F protein zf-CSL PF05207.13 KXX79938.1 - 6.8e-22 77.0 1.6 8.7e-22 76.6 1.6 1.1 1 0 0 1 1 1 1 CSL zinc finger Laminin_II PF06009.12 KXX79939.1 - 3.8 7.5 11.3 1.3 9.1 6.9 2.3 1 1 0 2 2 2 0 Laminin Domain II Herpes_UL14 PF03580.14 KXX79940.1 - 0.0084 16.4 2.4 0.0084 16.4 2.4 2.0 1 1 1 2 2 2 1 Herpesvirus UL14-like protein APG6_N PF17675.1 KXX79940.1 - 0.035 14.6 12.3 0.073 13.6 12.3 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Cauli_AT PF03233.13 KXX79940.1 - 0.054 13.4 1.8 0.075 13.0 1.8 1.3 1 0 0 1 1 1 0 Aphid transmission protein DUF3584 PF12128.8 KXX79940.1 - 0.055 11.0 10.7 0.063 10.8 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KXX79940.1 - 0.073 12.5 13.9 0.088 12.3 13.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Uso1_p115_C PF04871.13 KXX79940.1 - 0.083 13.3 14.1 0.16 12.4 13.4 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 KXX79940.1 - 0.15 11.6 7.9 0.21 11.2 7.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4618 PF15397.6 KXX79940.1 - 0.17 11.3 12.5 0.74 9.2 10.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) FapA PF03961.13 KXX79940.1 - 0.19 10.3 5.8 0.23 10.0 5.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_11 PF13086.6 KXX79940.1 - 0.63 9.8 9.2 0.8 9.4 9.2 1.1 1 0 0 1 1 1 0 AAA domain CENP-H PF05837.12 KXX79940.1 - 0.69 10.3 13.8 0.72 10.3 12.2 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 KXX79940.1 - 0.88 8.8 5.4 1.1 8.5 5.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 KXX79940.1 - 1.3 6.8 7.7 1.6 6.6 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 KXX79940.1 - 1.4 9.4 11.3 2 8.9 11.3 1.3 1 0 0 1 1 1 0 AAA domain DUF4164 PF13747.6 KXX79940.1 - 1.8 8.9 15.4 41 4.5 15.1 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 KXX79940.1 - 2.6 8.5 6.5 2.6 8.5 0.2 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 KXX79940.1 - 5 7.5 13.6 3.9 7.8 6.7 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein LMBR1 PF04791.16 KXX79940.1 - 9.2 5.0 11.1 6.9 5.4 10.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Cupredoxin_1 PF13473.6 KXX79941.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Herpes_capsid PF06112.11 KXX79941.1 - 2.2 8.3 9.0 3.5 7.7 9.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cyt-b5 PF00173.28 KXX79942.1 - 2e-07 31.0 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC_export PF16962.5 KXX79943.1 - 0.0017 16.9 4.2 0.027 12.9 1.6 2.3 2 0 0 2 2 2 2 Putative ABC exporter Yip1 PF04893.17 KXX79943.1 - 0.0024 17.6 4.1 0.0024 17.6 4.1 2.3 1 1 1 2 2 2 1 Yip1 domain DUF1129 PF06570.11 KXX79943.1 - 0.087 12.3 0.3 0.087 12.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF373 PF04123.13 KXX79943.1 - 2.7 7.3 12.3 0.3 10.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4149 PF13664.6 KXX79943.1 - 9.1 6.7 11.0 0.99 9.8 0.1 3.5 2 2 2 4 4 4 0 Domain of unknown function (DUF4149) CYYR1 PF10873.8 KXX79944.1 - 0.026 15.0 0.7 0.026 15.0 0.7 1.7 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Pex14_N PF04695.13 KXX79944.1 - 3.9 8.1 10.3 69 4.1 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.11 KXX79944.1 - 7.8 4.6 12.9 9.6 4.3 12.2 1.3 1 1 0 1 1 1 0 Special lobe-specific silk protein SSP160 HET PF06985.11 KXX79945.1 - 6.1e-17 62.3 0.0 2.5e-16 60.3 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr5 PF14420.6 KXX79946.1 - 4.5e-16 58.8 0.5 1.1e-15 57.5 0.5 1.7 1 0 0 1 1 1 1 Clr5 domain Utp14 PF04615.13 KXX79947.1 - 1.4 7.4 17.3 2.1 6.8 17.3 1.1 1 0 0 1 1 1 0 Utp14 protein Clat_adaptor_s PF01217.20 KXX79948.1 - 6.2e-43 146.1 0.0 8.8e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 KXX79949.1 - 2.5e-38 130.5 0.0 3.1e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Glyco_hydro38C2 PF17677.1 KXX79949.1 - 0.027 14.6 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain GMC_oxred_N PF00732.19 KXX79950.1 - 2.2e-57 194.7 0.0 3.3e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX79950.1 - 6.3e-28 98.1 0.0 1e-27 97.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase pKID PF02173.17 KXX79950.1 - 0.2 11.1 0.5 0.37 10.3 0.5 1.4 1 0 0 1 1 1 0 pKID domain tRNA-synt_1 PF00133.22 KXX79952.1 - 1.4e-38 132.5 0.0 4.7e-28 97.8 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXX79952.1 - 2.2e-17 62.9 0.0 8.1e-11 41.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXX79952.1 - 7.8e-15 55.1 1.0 1.3e-14 54.4 0.6 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXX79952.1 - 1.9e-08 34.0 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain BESS PF02944.20 KXX79953.1 - 0.017 14.9 1.1 0.033 14.0 1.1 1.5 1 0 0 1 1 1 0 BESS motif DUF4566 PF15130.6 KXX79953.1 - 0.03 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) BTB_2 PF02214.22 KXX79954.1 - 1.6e-07 31.6 0.1 0.00053 20.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Tubulin PF00091.25 KXX79955.1 - 1.5e-66 224.3 0.0 2.2e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXX79955.1 - 3.5e-50 169.4 0.1 5.9e-50 168.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXX79955.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain tRNA_U5-meth_tr PF05958.11 KXX79956.1 - 2.4e-07 30.1 0.0 1.2e-05 24.5 0.0 3.0 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KXX79956.1 - 0.0024 17.7 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX79956.1 - 0.0092 16.7 0.0 0.033 14.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXX79956.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ALG11_N PF15924.5 KXX79957.1 - 1.7e-83 279.8 0.0 2.7e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KXX79957.1 - 1.6e-21 76.6 0.0 2.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXX79957.1 - 9e-12 45.6 0.0 2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXX79957.1 - 0.00024 21.2 0.3 0.00049 20.1 0.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 60KD_IMP PF02096.20 KXX79958.1 - 0.0043 17.0 0.0 0.0087 16.0 0.0 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein Ferric_reduct PF01794.19 KXX79959.1 - 0.0002 21.4 2.0 0.00033 20.8 2.0 1.3 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Herpes_ORF11 PF04797.13 KXX79959.1 - 0.064 12.0 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein Trp_DMAT PF11991.8 KXX79960.1 - 3.5e-93 312.9 0.0 4.5e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase TetR_C_33 PF13305.6 KXX79960.1 - 0.13 13.0 1.1 0.71 10.6 0.1 2.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Acetyltransf_1 PF00583.25 KXX79961.1 - 0.061 13.6 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CysG_dimeriser PF10414.9 KXX79961.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Gly-zipper_Omp PF13488.6 KXX79962.1 - 1.5e-05 24.9 4.0 0.00071 19.5 0.2 2.4 2 0 0 2 2 2 2 Glycine zipper Rick_17kDa_Anti PF05433.15 KXX79962.1 - 0.00015 21.5 9.4 0.004 17.0 2.0 2.4 2 0 0 2 2 2 2 Glycine zipper 2TM domain DUF2530 PF10745.9 KXX79962.1 - 0.023 14.9 0.5 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) CbtA PF09490.10 KXX79962.1 - 0.029 14.2 2.3 0.048 13.4 2.3 1.5 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SARAF PF06682.12 KXX79962.1 - 5.3 6.6 8.5 16 5.0 0.2 2.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SelP_N PF04592.14 KXX79962.1 - 7.5 5.9 26.8 0.89 8.9 22.6 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF4129 PF13559.6 KXX79963.1 - 0.0025 18.0 0.1 0.0074 16.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Phage_GPD PF05954.11 KXX79963.1 - 0.019 14.3 1.1 0.028 13.7 1.1 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) NICE-3 PF07406.11 KXX79963.1 - 0.026 14.5 0.1 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 NICE-3 protein Lsm_interact PF05391.11 KXX79963.1 - 0.17 11.4 0.0 0.44 10.1 0.0 1.7 1 0 0 1 1 1 0 Lsm interaction motif DUF2427 PF10348.9 KXX79963.1 - 1.1 9.0 4.1 1.9 8.3 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) CD52 PF15116.6 KXX79963.1 - 8.8 6.5 9.4 2.8 8.0 4.3 2.8 2 1 0 2 2 2 0 CAMPATH-1 antigen DUF4938 PF16292.5 KXX79964.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4938) Hydrophobin PF01185.18 KXX79965.1 - 0.00039 21.0 4.6 0.00039 21.0 4.6 2.1 1 1 1 2 2 2 1 Fungal hydrophobin RINGv PF12906.7 KXX79966.1 - 6.1e-09 35.9 4.3 1.1e-08 35.1 0.9 2.2 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 KXX79966.1 - 0.0012 18.9 1.0 0.099 12.7 0.9 2.3 2 0 0 2 2 2 1 PHD-finger TatC PF00902.18 KXX79966.1 - 0.036 13.9 0.3 0.057 13.2 0.3 1.3 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) zf-RING_2 PF13639.6 KXX79966.1 - 0.76 10.2 5.5 1.5 9.2 1.4 2.2 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 KXX79966.1 - 0.86 9.5 6.1 0.23 11.4 2.6 1.8 2 0 0 2 2 2 0 PHD-finger Glyco_transf_34 PF05637.12 KXX79967.1 - 2e-77 260.1 0.0 2.5e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KXX79967.1 - 0.00027 20.6 0.0 0.039 13.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Citrate_synt PF00285.21 KXX79968.1 - 9.3e-21 74.3 0.0 7.9e-18 64.6 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KXX79968.1 - 2e-19 70.1 0.0 5.6e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KXX79968.1 - 7.5e-16 58.3 0.1 1.8e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXX79968.1 - 6.5e-06 26.0 0.0 0.00022 21.0 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 KXX79969.1 - 2.7e-87 290.8 0.1 3.8e-87 290.4 0.1 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KXX79969.1 - 5.9e-07 29.2 0.0 2e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KXX79969.1 - 0.0055 14.9 0.0 0.0078 14.4 0.0 1.1 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Arginosuc_synth PF00764.19 KXX79970.1 - 8.6e-138 459.8 0.0 3.4e-90 303.1 0.0 2.0 2 0 0 2 2 2 2 Arginosuccinate synthase QueC PF06508.13 KXX79970.1 - 0.049 13.1 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Mito_carr PF00153.27 KXX79971.1 - 1.4e-49 166.0 0.6 1.8e-17 63.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TetR_C_22 PF17928.1 KXX79971.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Serine_protease PF18405.1 KXX79971.1 - 0.19 10.9 0.4 0.69 9.0 0.1 2.0 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Calcipressin PF04847.12 KXX79972.1 - 2.1e-58 197.1 0.1 2.1e-58 197.1 0.1 1.9 2 1 0 2 2 2 1 Calcipressin DUF2722 PF10846.8 KXX79972.1 - 0.002 17.2 8.6 0.0034 16.4 7.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 KXX79972.1 - 0.089 12.4 15.5 0.12 12.0 15.5 1.2 1 0 0 1 1 1 0 Spt20 family RBM39linker PF15519.6 KXX79972.1 - 0.14 13.3 3.4 0.22 12.6 2.2 1.9 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Activator_LAG-3 PF11498.8 KXX79972.1 - 0.59 9.0 16.9 0.89 8.5 16.9 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 KXX79972.1 - 3.3 8.3 13.3 4.8 7.8 10.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_DNAp_acc PF04929.12 KXX79972.1 - 4.8 6.1 11.0 7.9 5.3 11.0 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.13 KXX79972.1 - 8.8 6.2 17.5 15 5.5 17.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA-synt_2d PF01409.20 KXX79973.1 - 1.2e-47 162.4 0.3 2.9e-24 85.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KXX79973.1 - 3.9e-26 91.3 0.0 8.1e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain WD40 PF00400.32 KXX79974.1 - 1.4e-10 41.5 7.5 0.0056 17.5 0.0 7.2 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX79974.1 - 3e-06 27.5 0.0 0.73 10.2 0.0 5.7 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain LVIVD PF08309.11 KXX79974.1 - 0.11 11.8 5.4 3 7.2 1.2 2.5 2 0 0 2 2 2 0 LVIVD repeat Neugrin PF06413.11 KXX79975.1 - 7.3e-13 49.1 1.8 7.3e-13 49.1 1.8 2.5 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KXX79975.1 - 0.00028 21.1 7.3 0.00028 21.1 7.3 3.2 2 2 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 Glyco_hydro_72 PF03198.14 KXX79976.1 - 4.3e-116 387.6 0.1 5.2e-116 387.3 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXX79976.1 - 0.0044 16.5 0.0 0.048 13.1 0.0 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) WLM PF08325.10 KXX79977.1 - 7.3e-52 176.2 0.0 1e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KXX79977.1 - 0.0017 18.4 0.2 0.0017 18.4 0.2 2.2 3 0 0 3 3 3 1 Protein of unknown function DUF45 SprT-like PF10263.9 KXX79977.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 SprT-like family Proteasome PF00227.26 KXX79978.1 - 2.5e-57 193.4 0.0 3.2e-33 114.8 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXX79978.1 - 1.3e-10 40.7 0.3 3.2e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 KXX79978.1 - 0.31 9.7 1.8 12 4.5 0.0 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Pyridoxal_deC PF00282.19 KXX79979.1 - 7e-14 51.3 0.0 1.1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXX79979.1 - 0.00055 19.0 0.0 0.0011 18.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXX79979.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribonuclease_3 PF00636.26 KXX79980.1 - 2.2e-33 115.0 0.0 2.2e-16 60.4 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KXX79980.1 - 5.6e-24 84.1 0.1 6.7e-23 80.7 0.1 2.7 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KXX79980.1 - 3e-17 63.0 0.0 3.1e-06 27.4 0.0 3.9 3 1 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.31 KXX79980.1 - 9.2e-17 61.4 0.0 3.4e-16 59.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX79980.1 - 3.1e-15 56.4 0.1 1.7e-13 50.7 0.1 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KXX79980.1 - 1.4e-08 34.9 0.0 2.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 KXX79980.1 - 0.0012 19.6 0.0 0.003 18.3 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF3638 PF12340.8 KXX79980.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) RCC1_2 PF13540.6 KXX79981.1 - 2.1e-17 62.4 13.4 3.5e-08 33.0 0.5 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXX79981.1 - 1.9e-15 57.2 0.5 0.00057 20.4 0.0 4.5 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat CENP-Q PF13094.6 KXX79983.1 - 2.3e-51 174.4 0.3 2.3e-51 174.4 0.3 2.2 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit RBR PF17208.3 KXX79983.1 - 1.7 9.4 14.0 12 6.6 7.1 3.1 1 1 1 2 2 2 0 RNA binding Region Ribosomal_L30 PF00327.20 KXX79984.1 - 1.4e-15 56.8 0.1 2e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.13 KXX79985.1 - 2.4e-61 206.5 0.7 3.2e-61 206.1 0.7 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KXX79985.1 - 1.4e-06 28.1 0.5 2.7e-06 27.2 0.5 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KXX79985.1 - 0.051 13.5 0.6 0.12 12.2 0.6 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DLIC PF05783.11 KXX79985.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Cnl2_NKP2 PF09447.10 KXX79987.1 - 1.2e-26 92.6 1.9 2.1e-26 91.9 1.9 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Syntaxin_2 PF14523.6 KXX79988.1 - 1.3e-27 96.1 1.2 1.3e-27 96.1 1.2 2.9 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KXX79988.1 - 3.7e-17 62.1 0.6 8.3e-17 60.9 0.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KXX79988.1 - 9.3e-05 22.2 10.8 0.00024 20.9 10.8 1.7 1 1 0 1 1 1 1 Syntaxin Prominin PF05478.11 KXX79988.1 - 0.00015 20.0 2.5 0.00017 19.8 2.5 1.0 1 0 0 1 1 1 1 Prominin VCX_VCY PF15231.6 KXX79988.1 - 0.032 14.9 0.1 0.049 14.3 0.1 1.3 1 0 0 1 1 1 0 Variable charge X/Y family Synaptobrevin PF00957.21 KXX79988.1 - 0.06 13.1 0.8 0.25 11.2 0.1 2.4 2 1 1 3 3 3 0 Synaptobrevin DUF948 PF06103.11 KXX79988.1 - 0.07 13.4 0.9 4.7 7.5 0.3 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nre_C PF04895.12 KXX79988.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.3 3 0 0 3 3 3 0 Archaeal Nre, C-terminal DUF883 PF05957.13 KXX79988.1 - 0.23 12.1 9.8 4.2 8.0 0.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) PCRF PF03462.18 KXX79988.1 - 0.34 10.7 7.2 0.27 11.1 4.6 2.2 1 1 1 2 2 2 0 PCRF domain T3SSipB PF16535.5 KXX79988.1 - 0.49 10.9 13.7 0.61 10.5 9.5 2.4 1 1 0 2 2 2 0 Type III cell invasion protein SipB UPF0242 PF06785.11 KXX79988.1 - 2.7 8.1 15.0 7.7 6.6 11.9 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 KXX79988.1 - 7.2 5.7 6.5 20 4.3 1.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein GrpE PF01025.19 KXX79989.1 - 3.1e-49 166.8 7.0 4e-49 166.5 7.0 1.1 1 0 0 1 1 1 1 GrpE Peptidase_S49 PF01343.18 KXX79989.1 - 0.34 10.8 2.5 0.38 10.7 1.6 1.5 1 1 0 1 1 1 0 Peptidase family S49 RNA_pol_A_bac PF01000.26 KXX79990.1 - 1.7e-31 108.9 0.0 2.5e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXX79990.1 - 4e-19 67.8 0.0 5.1e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Atg14 PF10186.9 KXX79991.1 - 0.014 14.5 14.5 0.029 13.5 14.5 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 KXX79991.1 - 0.26 9.2 8.5 0.36 8.7 8.5 1.1 1 0 0 1 1 1 0 Prominin IFT57 PF10498.9 KXX79991.1 - 0.41 9.6 8.7 0.68 8.8 8.7 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GAS PF13851.6 KXX79991.1 - 0.6 9.4 13.9 0.42 9.9 12.1 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding AI-2E_transport PF01594.16 KXX79991.1 - 0.65 9.1 6.5 0.78 8.8 0.0 2.2 2 0 0 2 2 2 0 AI-2E family transporter FUSC PF04632.12 KXX79991.1 - 0.75 8.3 26.9 1.4 7.4 26.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family EzrA PF06160.12 KXX79991.1 - 0.79 7.8 7.4 1.2 7.2 7.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA LMBR1 PF04791.16 KXX79991.1 - 1.1 8.1 4.7 1.5 7.6 4.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RIFIN PF02009.16 KXX79991.1 - 1.2 8.9 20.9 0.071 13.0 2.5 2.2 1 1 1 2 2 2 0 Rifin AAA_13 PF13166.6 KXX79991.1 - 1.3 7.5 14.5 1.8 7.1 14.5 1.1 1 0 0 1 1 1 0 AAA domain Phe_tRNA-synt_N PF02912.18 KXX79991.1 - 1.6 8.7 6.5 0.33 10.9 1.8 2.3 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF4776 PF16003.5 KXX79991.1 - 1.8 7.5 9.7 2.5 7.0 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF948 PF06103.11 KXX79991.1 - 1.8 8.9 7.1 1.8 8.9 2.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 KXX79991.1 - 2.1 8.4 9.5 5.7 7.0 9.5 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.8 KXX79991.1 - 2.2 5.7 30.3 3 5.2 30.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 KXX79991.1 - 8.6 5.5 19.2 0.65 9.2 12.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF966 PF06136.13 KXX79991.1 - 9.8 5.8 21.2 20 4.7 21.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ER_lumen_recept PF00810.18 KXX79992.1 - 7.5e-55 185.8 8.3 1.3e-54 185.0 8.3 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXX79992.1 - 0.044 13.5 0.1 0.044 13.5 0.1 4.0 6 0 0 6 6 6 0 PQ loop repeat Rgp1 PF08737.10 KXX79993.1 - 6e-161 536.3 0.0 9.5e-161 535.6 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KXX79993.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXX79993.1 - 0.11 13.0 0.0 0.47 10.9 0.0 2.1 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain LicD PF04991.13 KXX79994.1 - 0.024 14.8 0.0 0.065 13.4 0.0 1.5 1 1 1 2 2 2 0 LicD family RFC1 PF08519.12 KXX79995.1 - 6.8e-60 201.8 0.0 1.6e-59 200.6 0.0 1.7 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KXX79995.1 - 4.1e-13 49.5 0.0 1.2e-12 48.0 0.0 1.9 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KXX79995.1 - 7.2e-09 36.2 0.0 2.3e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXX79995.1 - 8.3e-07 29.1 0.0 2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KXX79995.1 - 5.5e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 KXX79995.1 - 0.0017 18.9 0.1 0.013 16.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX79995.1 - 0.0074 16.7 2.7 0.057 13.8 0.1 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXX79995.1 - 0.0098 16.2 0.0 0.41 10.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXX79995.1 - 0.017 15.2 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXX79995.1 - 0.025 14.8 2.5 0.061 13.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXX79995.1 - 0.027 14.7 0.0 0.089 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXX79995.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KXX79995.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 KXX79995.1 - 4.4 7.0 8.2 13 5.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain DNA_pol3_delta2 PF13177.6 KXX79997.1 - 1.7e-11 44.2 0.0 3.1e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KXX79997.1 - 7.5e-07 29.6 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX79997.1 - 6.7e-06 26.4 0.1 7.2e-05 23.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXX79997.1 - 0.00019 21.8 0.5 0.005 17.2 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KXX79997.1 - 0.00036 20.3 0.2 0.0011 18.7 0.2 1.8 2 1 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 KXX79997.1 - 0.0015 18.9 0.1 0.005 17.2 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 KXX79997.1 - 0.0046 16.9 0.0 0.0097 15.8 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 KXX79997.1 - 0.011 16.2 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DNA_pol3_delta PF06144.13 KXX79997.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit T4SS-DNA_transf PF02534.14 KXX79997.1 - 0.05 12.4 0.1 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ATPase_2 PF01637.18 KXX79997.1 - 0.081 12.8 0.1 0.21 11.5 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Ribosomal_L16 PF00252.18 KXX79998.1 - 1.8e-33 115.3 0.2 2.9e-33 114.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ndc1_Nup PF09531.10 KXX79999.1 - 4.2e-196 653.3 0.1 4.7e-196 653.1 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Methyltransf_25 PF13649.6 KXX80000.1 - 1.4e-14 54.6 0.0 2.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX80000.1 - 7.5e-12 45.9 0.0 1.1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX80000.1 - 6.3e-11 42.8 0.0 9.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX80000.1 - 4e-08 33.2 0.0 5.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX80000.1 - 2.8e-07 30.1 0.0 4.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXX80000.1 - 3.5e-06 26.9 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX80000.1 - 0.00019 21.0 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KXX80000.1 - 0.0059 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 KXX80000.1 - 0.0093 15.4 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KXX80000.1 - 0.23 11.0 0.0 0.33 10.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) SPESP1 PF15754.5 KXX80003.1 - 0.0087 15.3 2.9 0.016 14.4 2.9 1.4 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 Trypan_PARP PF05887.11 KXX80003.1 - 0.019 14.9 22.4 0.019 14.9 22.4 3.6 4 0 0 4 4 4 0 Procyclic acidic repetitive protein (PARP) DOR PF14839.6 KXX80003.1 - 0.03 14.3 0.0 0.03 14.3 0.0 2.5 3 1 0 3 3 3 0 DOR family Mac PF12464.8 KXX80003.1 - 0.079 13.2 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 Maltose acetyltransferase Aldolase_II PF00596.21 KXX80005.1 - 4.9e-32 111.4 0.0 6.1e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SH3_1 PF00018.28 KXX80006.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX80006.1 - 0.0045 16.8 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX80006.1 - 0.046 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Dynamin_N PF00350.23 KXX80007.1 - 1.1e-36 126.5 0.1 2e-36 125.6 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXX80007.1 - 5.6e-23 81.6 0.0 3e-22 79.2 0.0 2.0 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KXX80007.1 - 8.4e-05 22.6 0.0 0.00044 20.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Med9 PF07544.13 KXX80007.1 - 0.0014 18.7 1.6 0.025 14.6 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 GED PF02212.18 KXX80007.1 - 0.0033 17.5 0.4 0.021 14.9 0.1 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.27 KXX80007.1 - 0.056 14.0 0.0 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_15 PF13175.6 KXX80007.1 - 0.085 12.6 0.2 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KXX80007.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KXX80007.1 - 0.2 11.9 0.0 5.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Snapin_Pallidin PF14712.6 KXX80007.1 - 0.46 10.9 2.2 11 6.5 0.0 3.4 4 0 0 4 4 4 0 Snapin/Pallidin Ank_2 PF12796.7 KXX80008.1 - 8.8e-85 279.4 13.2 6.8e-16 58.6 0.1 7.1 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX80008.1 - 4.5e-56 186.5 13.1 3.4e-10 40.3 0.0 10.4 3 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX80008.1 - 1.9e-52 169.1 11.6 2.6e-05 24.3 0.0 14.1 14 0 0 14 14 14 11 Ankyrin repeat Ank PF00023.30 KXX80008.1 - 1.1e-50 168.0 27.9 1.2e-06 28.7 0.0 13.6 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 KXX80008.1 - 2.1e-47 158.5 15.8 1.9e-09 37.6 0.0 11.4 5 3 7 12 12 12 9 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KXX80008.1 - 5.4e-05 22.7 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins MRP-L28 PF09812.9 KXX80009.1 - 0.068 13.3 1.3 2.8 8.1 0.6 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L28 IFT57 PF10498.9 KXX80009.1 - 0.069 12.1 2.6 0.12 11.3 2.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KXX80009.1 - 0.12 11.2 6.0 0.22 10.4 6.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CK2S PF15011.6 KXX80009.1 - 0.14 12.0 3.1 0.24 11.3 2.1 1.8 2 0 0 2 2 2 0 Casein Kinase 2 substrate MetOD2 PF18548.1 KXX80009.1 - 0.17 12.0 2.8 0.22 11.6 0.7 2.2 2 0 0 2 2 2 0 Metanogen output domain 2 Phlebovirus_NSM PF07246.11 KXX80009.1 - 0.28 10.5 4.3 0.47 9.8 4.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Sipho_Gp157 PF05565.11 KXX80009.1 - 0.43 10.6 4.9 0.85 9.6 4.9 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 Promethin PF16015.5 KXX80010.1 - 0.33 10.9 7.2 1.2 9.1 1.0 2.2 2 0 0 2 2 2 0 Promethin FAD_binding_3 PF01494.19 KXX80011.1 - 3.6e-14 52.8 0.0 5.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_C PF05199.13 KXX80012.1 - 6.9e-32 110.9 0.0 1.1e-31 110.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXX80012.1 - 2.3e-29 102.7 0.0 7.1e-25 88.0 0.0 3.4 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KXX80012.1 - 0.00035 20.7 0.1 0.0012 19.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX80012.1 - 0.0061 15.7 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX80012.1 - 0.0065 15.7 0.1 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX80012.1 - 0.093 12.0 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXX80012.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KXX80012.1 - 0.15 11.4 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 KXX80012.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GFA PF04828.14 KXX80013.1 - 7.9e-13 48.6 1.8 2e-07 31.2 1.2 3.2 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Herpes_Helicase PF02689.14 KXX80014.1 - 0.00047 18.2 0.0 0.00063 17.8 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KXX80014.1 - 0.0005 19.9 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Abhydrolase_3 PF07859.13 KXX80015.1 - 2.6e-29 102.6 0.0 4.1e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXX80015.1 - 0.00036 19.6 0.0 0.00066 18.7 0.0 1.3 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXX80015.1 - 0.0011 19.7 2.5 0.0011 19.7 2.5 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX80015.1 - 0.0093 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXX80015.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.12 KXX80015.1 - 0.028 13.1 0.1 0.052 12.2 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AOX PF01786.17 KXX80016.1 - 1.5e-81 273.1 0.0 1.9e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase ADH_zinc_N_2 PF13602.6 KXX80019.1 - 6.7e-28 98.4 0.0 9.6e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX80019.1 - 8.2e-16 58.2 0.1 1.3e-15 57.5 0.1 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PH_8 PF15409.6 KXX80020.1 - 0.035 14.4 0.7 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1232 PF06803.12 KXX80020.1 - 0.073 12.9 1.9 0.27 11.1 1.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Esterase_phd PF10503.9 KXX80021.1 - 1.3e-22 80.4 0.5 1.7e-22 80.0 0.5 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXX80021.1 - 6.2e-09 35.6 0.7 1e-08 35.0 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXX80021.1 - 0.00025 20.8 0.8 0.00038 20.2 0.8 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KXX80021.1 - 0.022 14.6 0.2 0.077 12.8 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXX80021.1 - 0.039 13.7 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KXX80021.1 - 0.055 13.4 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 KXX80021.1 - 0.063 12.6 1.4 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase DLH PF01738.18 KXX80021.1 - 0.2 11.2 1.3 0.58 9.7 1.3 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Eapp_C PF10238.9 KXX80022.1 - 0.0014 18.8 3.4 2 8.5 0.0 2.1 2 0 0 2 2 2 2 E2F-associated phosphoprotein DUF4419 PF14388.6 KXX80023.1 - 6.8e-98 327.8 0.0 9.5e-98 327.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) TPR_1 PF00515.28 KXX80025.1 - 5.3e-46 152.6 33.0 3.1e-06 26.8 0.1 11.3 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 KXX80025.1 - 5.7e-40 132.2 29.7 3.9e-05 23.5 0.0 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.6 KXX80025.1 - 4.2e-24 84.9 13.5 2e-06 28.3 0.3 7.6 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXX80025.1 - 5.3e-22 77.2 25.5 1.8e-05 24.3 0.0 9.1 5 2 4 9 9 9 6 TPR repeat TPR_17 PF13431.6 KXX80025.1 - 1.8e-20 71.7 13.1 0.0031 17.8 0.6 8.9 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX80025.1 - 2e-19 68.1 33.4 0.00015 21.7 0.0 11.3 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXX80025.1 - 1.3e-18 67.1 30.4 0.004 17.4 0.6 8.8 3 2 4 8 8 8 7 Tetratricopeptide repeat TPR_9 PF13371.6 KXX80025.1 - 3.2e-14 52.8 12.3 2e-06 27.8 0.2 6.3 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXX80025.1 - 4.9e-13 49.4 24.9 0.00064 20.2 1.3 7.9 4 2 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXX80025.1 - 2.8e-10 40.1 21.5 0.012 16.4 0.2 9.6 5 3 6 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX80025.1 - 2.7e-09 36.4 26.0 0.094 12.8 0.2 9.6 9 1 1 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX80025.1 - 4.9e-09 36.3 19.0 0.2 11.9 0.0 5.7 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 KXX80025.1 - 9.4e-07 28.2 9.2 0.078 12.4 0.0 6.1 6 0 0 6 6 6 2 SHNi-TPR TPR_15 PF13429.6 KXX80025.1 - 1.9e-05 24.1 8.4 0.24 10.6 0.8 5.4 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX80025.1 - 0.00011 21.7 1.4 0.00011 21.7 1.4 2.4 2 1 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 KXX80025.1 - 0.00016 21.4 26.4 0.25 11.2 0.5 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat DUF3856 PF12968.7 KXX80025.1 - 0.00074 19.6 5.5 5.3 7.1 0.0 5.7 4 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) preATP-grasp_3 PF18301.1 KXX80025.1 - 0.0082 16.4 0.1 0.14 12.5 0.2 2.8 3 0 0 3 3 3 1 pre ATP-grasp 3 domain MIT PF04212.18 KXX80025.1 - 0.022 14.8 18.6 14 5.8 0.0 6.8 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TAF1_subA PF14929.6 KXX80025.1 - 0.2 11.0 1.7 0.3 10.5 0.2 1.8 2 1 0 2 2 2 0 TAF RNA Polymerase I subunit A NARP1 PF12569.8 KXX80025.1 - 0.24 10.3 24.8 0.095 11.6 0.5 4.4 2 2 0 4 4 4 0 NMDA receptor-regulated protein 1 Sel1 PF08238.12 KXX80025.1 - 0.26 12.0 3.2 1.8 9.4 0.1 3.8 3 0 0 3 3 3 0 Sel1 repeat MAS20 PF02064.15 KXX80025.1 - 0.61 10.2 14.4 3.7 7.7 2.1 4.5 5 1 1 6 6 5 0 MAS20 protein import receptor TPR_20 PF14561.6 KXX80025.1 - 2.4 8.5 10.3 13 6.2 0.3 5.0 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX80025.1 - 4.2 8.2 25.8 32 5.4 0.0 9.2 10 0 0 10 10 9 0 Tetratricopeptide repeat Syntaxin PF00804.25 KXX80026.1 - 3.8e-19 69.1 6.1 3.8e-19 69.1 6.1 1.9 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KXX80026.1 - 6.4e-11 42.1 0.8 1.7e-10 40.7 0.8 1.8 1 0 0 1 1 1 1 SNARE domain SKA2 PF16740.5 KXX80026.1 - 0.04 13.7 0.6 0.04 13.7 0.6 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF2951 PF11166.8 KXX80026.1 - 0.097 12.9 0.3 0.097 12.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF3018 PF11455.8 KXX80026.1 - 2 8.4 5.7 1.9 8.5 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3018) Synaptobrevin PF00957.21 KXX80026.1 - 2.4 8.0 8.0 0.27 11.0 2.2 2.3 2 1 1 3 3 3 0 Synaptobrevin Baculo_PEP_C PF04513.12 KXX80026.1 - 3 7.9 16.2 1.7 8.7 2.8 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KXX80026.1 - 5.9 7.6 14.7 0.082 13.5 2.2 3.2 2 1 2 4 4 4 0 SlyX FUSC PF04632.12 KXX80026.1 - 6.3 5.2 10.8 4.2 5.8 3.6 2.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.7 KXX80026.1 - 7.1 6.8 8.2 2 8.6 0.6 2.3 2 0 0 2 2 2 0 Tropomyosin like BRE1 PF08647.11 KXX80026.1 - 8.1 6.6 9.8 2.9 8.0 0.5 3.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Brix PF04427.18 KXX80027.1 - 4.3e-30 105.3 0.2 5.5e-30 104.9 0.2 1.1 1 0 0 1 1 1 1 Brix domain AAA PF00004.29 KXX80028.1 - 9.8e-16 58.4 0.0 2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXX80028.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXX80028.1 - 0.038 14.2 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX80028.1 - 0.063 13.7 0.2 0.22 11.9 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXX80028.1 - 0.073 13.6 0.0 0.32 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXX80028.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.9 3 1 1 4 4 4 0 AAA domain PKD_channel PF08016.12 KXX80029.1 - 7.3e-06 24.9 15.4 0.00018 20.3 15.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KXX80029.1 - 8.4e-05 21.9 21.8 0.001 18.4 21.8 2.1 1 1 0 1 1 1 1 Ion transport protein UPF0542 PF15086.6 KXX80029.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Sigma_reg_N PF13800.6 KXX80029.1 - 1.5 9.1 3.4 11 6.4 0.1 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Ac76 PF05814.11 KXX80029.1 - 2.1 8.4 6.5 0.91 9.6 0.4 2.9 2 0 0 2 2 2 0 Orf76 (Ac76) Asp PF00026.23 KXX80030.1 - 6.9e-13 48.7 0.2 2.3e-09 37.1 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KXX80030.1 - 0.13 12.8 0.1 0.98 10.0 0.1 2.1 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Aminotran_4 PF01063.19 KXX80031.1 - 8.2e-21 74.9 0.0 1.7e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV Myosin-VI_CBD PF16521.5 KXX80031.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Myosin VI cargo binding domain XAP5 PF04921.14 KXX80032.1 - 1.3e-93 313.4 0.0 3.8e-93 311.9 0.0 1.7 1 1 1 2 2 2 2 XAP5, circadian clock regulator DUF4604 PF15377.6 KXX80032.1 - 0.013 16.0 4.1 0.013 16.0 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Herpes_US12 PF05363.12 KXX80032.1 - 0.13 13.0 4.0 0.11 13.2 0.8 2.5 2 0 0 2 2 2 0 Herpesvirus US12 family Methyltransf_10 PF05971.12 KXX80033.1 - 7e-66 222.6 0.0 9e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KXX80033.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXX80033.1 - 0.0027 18.4 0.0 0.043 14.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX80033.1 - 0.024 14.4 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 KXX80033.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXX80033.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KXX80033.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 KXX80033.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HMMR_N PF15905.5 KXX80034.1 - 8.5e-06 25.5 26.4 8.5e-06 25.5 26.4 2.4 1 1 1 2 2 1 1 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KXX80034.1 - 0.0004 19.8 19.2 0.0004 19.8 19.2 3.5 1 1 2 3 3 2 2 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 KXX80034.1 - 0.00041 20.6 29.2 0.0066 16.7 16.2 4.8 1 1 2 4 4 4 1 Domain of unknown function (DUF5082) HAP1_N PF04849.13 KXX80034.1 - 0.00065 19.0 20.6 0.00065 19.0 20.6 2.4 1 1 1 2 2 1 1 HAP1 N-terminal conserved region Lebercilin PF15619.6 KXX80034.1 - 0.00088 19.0 13.2 0.00088 19.0 13.2 2.9 1 1 1 2 2 1 1 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 KXX80034.1 - 0.0017 17.3 23.8 0.0017 17.3 23.8 2.5 1 1 1 2 2 2 1 Spc7 kinetochore protein ERM PF00769.19 KXX80034.1 - 0.0021 18.0 26.1 0.0021 18.0 26.1 3.0 1 1 2 3 3 2 1 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 KXX80034.1 - 0.0032 17.5 14.6 0.0032 17.5 14.6 3.8 1 1 3 4 4 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 KXX80034.1 - 0.0045 17.2 11.4 0.0045 17.2 11.4 2.9 3 1 1 4 4 2 1 Fibrinogen alpha/beta chain family SlyX PF04102.12 KXX80034.1 - 0.006 17.2 21.3 0.017 15.7 9.9 4.3 1 1 3 4 4 4 2 SlyX Tropomyosin_1 PF12718.7 KXX80034.1 - 0.0088 16.2 16.1 0.0088 16.2 16.1 4.3 2 1 3 5 5 3 2 Tropomyosin like NBP1 PF08537.10 KXX80034.1 - 0.01 15.3 19.4 0.015 14.7 19.4 1.2 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 ADIP PF11559.8 KXX80034.1 - 0.013 15.6 11.4 0.013 15.6 11.4 3.5 1 1 3 4 4 3 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 KXX80034.1 - 0.016 15.6 11.0 0.016 15.6 11.0 4.6 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.19 KXX80034.1 - 0.021 12.6 47.7 0.23 9.2 47.7 2.1 1 1 0 1 1 1 0 Myosin tail PKcGMP_CC PF16808.5 KXX80034.1 - 0.023 14.6 0.8 0.023 14.6 0.8 5.8 6 2 1 8 8 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Gp58 PF07902.11 KXX80034.1 - 0.04 12.2 6.9 0.068 11.5 6.9 1.4 1 0 0 1 1 1 0 gp58-like protein TolA_bind_tri PF16331.5 KXX80034.1 - 0.041 14.0 18.3 0.69 10.0 7.8 2.9 1 1 0 2 2 2 0 TolA binding protein trimerisation ATG16 PF08614.11 KXX80034.1 - 0.068 13.4 44.9 0.2 11.8 14.7 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 KXX80034.1 - 0.087 11.9 21.7 0.11 11.6 20.4 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HOOK PF05622.12 KXX80034.1 - 0.091 10.9 39.7 0.14 10.2 39.7 1.2 1 0 0 1 1 1 0 HOOK protein DUF3584 PF12128.8 KXX80034.1 - 0.13 9.8 45.6 0.17 9.3 45.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KXX80034.1 - 0.33 11.0 14.5 0.18 11.8 8.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KXX80034.1 - 0.36 9.7 46.2 0.9 8.3 46.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) GIT_CC PF16559.5 KXX80034.1 - 0.72 9.8 9.9 0.2 11.5 0.5 2.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor End3 PF12761.7 KXX80034.1 - 0.78 9.9 31.0 0.016 15.4 18.4 2.4 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Golgin_A5 PF09787.9 KXX80034.1 - 0.94 8.9 41.6 0.56 9.6 14.5 2.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 DASH_Hsk3 PF08227.11 KXX80034.1 - 0.95 9.9 0.1 0.95 9.9 0.1 3.8 4 1 1 5 5 4 0 DASH complex subunit Hsk3 like DUF641 PF04859.12 KXX80034.1 - 1.8 8.9 33.9 0.055 13.8 4.7 3.9 1 1 2 3 3 2 0 Plant protein of unknown function (DUF641) Med9 PF07544.13 KXX80034.1 - 2.1 8.5 13.6 2.3 8.4 2.6 3.6 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 IFT57 PF10498.9 KXX80034.1 - 2.6 6.9 32.9 4.7 6.1 32.9 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 KXX80034.1 - 3.9 8.0 10.0 4.5e+02 1.4 9.0 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KXX80034.1 - 5 6.4 46.5 0.042 13.2 20.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 KXX80034.1 - 5.4 7.4 33.9 0.64 10.4 4.7 5.3 2 2 3 5 5 4 0 Csm1 N-terminal domain DUF4763 PF15960.5 KXX80034.1 - 5.9 6.1 24.8 0.32 10.3 14.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) FPP PF05911.11 KXX80034.1 - 6.4 4.8 43.7 41 2.1 43.8 1.9 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF16 PF01519.16 KXX80034.1 - 9.3 6.8 26.7 0.95 10.0 4.8 3.5 1 1 1 2 2 1 0 Protein of unknown function DUF16 Bacillus_HBL PF05791.11 KXX80034.1 - 9.6 6.0 15.3 13 5.5 9.6 2.7 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Prefoldin PF02996.17 KXX80034.1 - 9.8 6.1 29.9 0.25 11.3 4.0 4.9 2 2 2 5 5 5 0 Prefoldin subunit Cortex-I_coil PF09304.10 KXX80035.1 - 0.001 19.2 0.6 0.0013 18.9 0.6 1.2 1 0 0 1 1 1 1 Cortexillin I, coiled coil MobL PF18555.1 KXX80035.1 - 0.01 15.1 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 MobL relaxases DUF842 PF05811.13 KXX80035.1 - 0.01 15.5 1.0 0.016 14.9 1.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DHC_N1 PF08385.12 KXX80035.1 - 0.015 14.0 0.1 0.017 13.8 0.1 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 PP2C_C PF07830.13 KXX80035.1 - 0.054 13.9 1.0 0.13 12.7 0.3 1.9 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Lipoprotein_6 PF01441.19 KXX80035.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein FliT PF05400.13 KXX80035.1 - 0.22 12.3 0.4 0.22 12.3 0.4 2.4 1 1 1 2 2 2 0 Flagellar protein FliT ThrE PF06738.12 KXX80035.1 - 0.28 10.5 0.0 0.51 9.7 0.0 1.2 1 1 0 1 1 1 0 Putative threonine/serine exporter Peptidase_M20 PF01546.28 KXX80036.1 - 1.6e-34 119.5 0.0 2.8e-34 118.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXX80036.1 - 8e-13 48.3 0.0 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXX80036.1 - 4.6e-05 23.2 0.0 8.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TMEM247 PF15444.6 KXX80039.1 - 0.57 10.2 2.1 0.71 9.9 2.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 DUF1180 PF06679.12 KXX80039.1 - 1.3 9.4 6.1 1.8 8.9 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Gag_p10 PF02337.17 KXX80040.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral GAG p10 protein Clr5 PF14420.6 KXX80041.1 - 2e-20 72.7 0.3 4.6e-20 71.6 0.3 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KXX80041.1 - 0.017 15.4 0.0 0.15 12.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_31 PF01055.26 KXX80042.1 - 2.5e-93 313.7 2.8 3.5e-93 313.2 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 KXX80042.1 - 0.064 13.5 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) HrpF PF06266.12 KXX80043.1 - 0.015 15.6 0.9 0.015 15.6 0.9 2.3 2 0 0 2 2 2 0 HrpF protein DUF1664 PF07889.12 KXX80043.1 - 6.1 6.9 9.8 0.99 9.4 3.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NMO PF03060.15 KXX80045.1 - 1.5e-29 103.4 7.5 3.3e-24 85.9 3.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KXX80045.1 - 2.3e-09 36.7 0.2 0.0013 17.8 0.0 2.0 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXX80045.1 - 4.8e-06 25.8 2.8 6e-06 25.5 2.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase adh_short PF00106.25 KXX80046.1 - 1.3e-46 158.6 4.2 1.6e-46 158.2 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX80046.1 - 1.2e-44 152.6 3.5 1.4e-44 152.4 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX80046.1 - 7.3e-10 39.0 1.0 1.4e-09 38.1 1.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX80046.1 - 0.00047 19.7 0.1 0.00084 18.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX80046.1 - 0.00062 19.3 0.0 0.0016 17.9 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXX80046.1 - 0.0014 18.5 0.5 0.0024 17.8 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KXX80046.1 - 0.0044 16.2 0.2 0.0064 15.6 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXX80046.1 - 0.0091 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXX80046.1 - 0.014 14.4 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KXX80046.1 - 0.023 15.3 0.4 0.048 14.2 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 KXX80046.1 - 0.025 14.4 1.6 0.05 13.4 1.6 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 KXX80046.1 - 0.031 13.6 0.1 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KXX80046.1 - 0.033 13.6 0.2 0.068 12.5 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 KXX80046.1 - 0.046 13.3 0.8 0.079 12.5 0.8 1.4 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 KXX80046.1 - 0.051 13.8 0.2 0.086 13.1 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain tRNA-synt_1e PF01406.19 KXX80047.1 - 1.9e-111 372.3 0.2 3.1e-111 371.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 KXX80047.1 - 0.00018 21.9 0.0 0.00075 19.9 0.0 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 KXX80047.1 - 0.00099 18.0 0.1 0.69 8.6 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) AMP-binding PF00501.28 KXX80048.1 - 3.1e-88 296.2 0.0 3.7e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX80048.1 - 2.5e-21 76.4 0.2 6.5e-21 75.1 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.15 KXX80051.1 - 3e-14 53.4 0.0 6.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Peptidase_S64 PF08192.11 KXX80052.1 - 0.28 9.6 0.0 0.53 8.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 Glyco_hydro_61 PF03443.14 KXX80054.1 - 1e-13 51.7 0.0 1.2e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.11 KXX80055.1 - 3.4e-29 102.1 0.0 1.2e-28 100.3 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ricin_B_lectin PF00652.22 KXX80056.1 - 1.9e-16 60.5 5.5 2.3e-09 37.6 0.3 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXX80056.1 - 1.9e-09 38.1 3.7 1.7e-06 28.7 0.5 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SnoaL PF07366.12 KXX80057.1 - 5.8e-14 52.0 0.2 4e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXX80057.1 - 1.1e-05 26.0 0.2 8.9e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 SnoaL-like domain RhoGAP PF00620.27 KXX80059.1 - 1.1e-15 57.8 0.0 2.4e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain Helo_like_N PF17111.5 KXX80059.1 - 1.8e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AP_endonuc_2 PF01261.24 KXX80061.1 - 1.4e-38 132.5 0.0 2.1e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 KXX80061.1 - 0.068 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus PTS_2-RNA PF01885.16 KXX80063.1 - 1.8e-23 83.6 0.0 2.4e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF4939 PF16297.5 KXX80063.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Methyltransf_31 PF13847.6 KXX80064.1 - 1.2e-05 25.2 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX80064.1 - 2.6e-05 24.8 0.0 4.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX80064.1 - 4.1e-05 24.1 0.0 6.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX80064.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX80064.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family 6PGD PF00393.19 KXX80065.1 - 1.7e-93 313.2 0.0 2.2e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXX80065.1 - 8.7e-30 104.0 0.1 2.4e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KXX80065.1 - 0.0023 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KXX80065.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 KXX80066.1 - 0.028 14.6 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NIF PF03031.18 KXX80067.1 - 1.9e-38 131.7 0.0 2.7e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Suf PF05843.14 KXX80067.1 - 2.5 8.0 7.2 5 7.0 7.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Myosin_head PF00063.21 KXX80068.1 - 7.9e-265 880.3 0.0 1.9e-264 879.0 0.0 1.7 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KXX80068.1 - 8.6e-14 51.1 0.8 2.4e-13 49.7 0.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KXX80068.1 - 3.3e-12 45.1 108.2 3.3e-12 45.1 108.2 7.1 3 2 3 6 6 6 3 Myosin tail TsaE PF02367.17 KXX80068.1 - 0.049 13.6 0.2 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KXX80068.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.7 5 0 0 5 5 5 0 AAA domain UDPG_MGDP_dh_N PF03721.14 KXX80068.1 - 0.48 10.0 2.9 1.3 8.5 2.9 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LapD_MoxY_N PF16448.5 KXX80068.1 - 6.1 6.7 9.7 0.69 9.8 3.3 2.7 2 0 0 2 2 2 0 LapD/MoxY periplasmic domain COG2 PF06148.11 KXX80069.1 - 0.0083 16.2 0.4 0.25 11.5 0.0 2.5 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 SesA PF17107.5 KXX80069.1 - 0.025 14.8 2.4 2.1 8.5 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Baculo_PEP_C PF04513.12 KXX80069.1 - 0.095 12.7 4.1 2.7 8.0 0.9 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pro_isomerase PF00160.21 KXX80070.1 - 3.3e-55 186.7 0.0 3.8e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Flavoprotein PF02441.19 KXX80071.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Flavoprotein zf_UBZ PF18439.1 KXX80071.1 - 0.23 11.1 2.4 2 8.1 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 KXX80071.1 - 2.2 7.9 7.8 0.16 11.5 3.1 1.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) EST1_DNA_bind PF10373.9 KXX80072.1 - 1.2e-11 44.6 0.0 6.4e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Rad50_zn_hook PF04423.14 KXX80072.1 - 0.24 11.3 1.0 0.59 10.0 1.0 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif Oxysterol_BP PF01237.18 KXX80073.1 - 1.4e-132 442.1 0.1 1.8e-131 438.4 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 KXX80073.1 - 9.7e-17 60.8 0.1 2.3e-09 37.3 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX80073.1 - 2.1e-14 53.9 0.0 1.3e-09 38.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX80073.1 - 2.3e-14 53.1 1.3 0.0002 21.7 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXX80073.1 - 5.8e-13 49.1 0.0 1.5e-07 31.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 KXX80073.1 - 9e-12 45.4 0.8 1.8e-11 44.5 0.8 1.6 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KXX80073.1 - 2.3e-11 42.9 0.1 8.5e-05 22.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 KXX80073.1 - 5e-08 33.1 1.1 1.3e-07 31.8 1.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KXX80073.1 - 3.5e-05 24.2 3.2 0.0001 22.7 3.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain 4HBT_3 PF13622.6 KXX80074.1 - 1.9e-81 274.0 0.7 2.3e-81 273.7 0.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXX80074.1 - 4.3e-24 84.8 0.0 1.6e-11 44.2 0.0 4.0 3 1 0 3 3 3 3 Acyl-CoA thioesterase Ge1_WD40 PF16529.5 KXX80074.1 - 0.065 12.2 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C3H1 PF10650.9 KXX80075.1 - 0.0001 22.0 5.5 0.00018 21.1 5.5 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain GIT_SHD PF08518.11 KXX80076.1 - 6.9e-24 83.2 5.5 2.6e-12 46.1 2.1 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KXX80076.1 - 0.0031 17.6 4.5 0.0085 16.2 0.0 3.2 3 0 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term CLZ PF16526.5 KXX80076.1 - 0.055 13.8 0.4 0.055 13.8 0.4 4.1 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin_2 PF14523.6 KXX80076.1 - 0.077 13.4 21.9 0.97 9.8 0.0 4.7 4 1 1 5 5 5 0 Syntaxin-like protein PSII_Pbs27 PF13326.6 KXX80076.1 - 0.69 10.2 7.8 1.3e+02 2.9 8.0 3.6 2 2 0 2 2 2 0 Photosystem II Pbs27 APG6_N PF17675.1 KXX80076.1 - 1.6 9.2 43.4 6.4 7.3 21.9 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region HrcA PF01628.21 KXX80076.1 - 4 7.3 7.0 9.9 6.0 7.0 1.6 1 0 0 1 1 1 0 HrcA protein C terminal domain DUF1759 PF03564.15 KXX80076.1 - 5.1 7.0 5.8 4.4 7.2 0.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1759) pKID PF02173.17 KXX80076.1 - 9.9 5.7 7.9 0.17 11.3 0.3 2.2 2 0 0 2 2 2 0 pKID domain MARVEL PF01284.23 KXX80077.1 - 1.6e-11 44.4 11.0 2e-11 44.1 11.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain SH3_1 PF00018.28 KXX80078.1 - 1.7e-08 34.0 0.1 2.8e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX80078.1 - 8.5e-08 31.9 0.2 1.7e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX80078.1 - 9.3e-05 22.0 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.13 KXX80079.1 - 3.5e-83 277.9 0.0 4e-83 277.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF3807 PF12720.7 KXX80080.1 - 9.2e-57 192.3 8.7 1.1e-56 192.0 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Pannexin_like PF12534.8 KXX80080.1 - 0.088 11.9 2.6 0.11 11.6 2.6 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 CCDC106 PF15794.5 KXX80080.1 - 0.12 12.1 5.8 0.17 11.6 5.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ribosomal_60s PF00428.19 KXX80080.1 - 0.15 12.6 7.2 0.12 12.9 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3682 PF12446.8 KXX80080.1 - 0.31 11.5 8.7 1.6 9.2 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) NAD_binding_1 PF00175.21 KXX80081.1 - 5e-33 114.0 0.0 3.3e-32 111.4 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXX80081.1 - 6.7e-23 80.9 0.0 1.9e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXX80081.1 - 5.4e-10 39.6 0.0 2.8e-05 24.3 0.0 2.5 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXX80081.1 - 0.12 12.5 0.1 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Atg14 PF10186.9 KXX80082.1 - 2.7e-79 266.6 0.0 3.4e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF488 PF04343.13 KXX80083.1 - 0.29 11.8 2.3 1 10.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF488 Cyd_oper_YbgE PF09600.10 KXX80084.1 - 0.1 13.0 3.9 0.18 12.2 3.9 1.4 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Pox_A_type_inc PF04508.12 KXX80084.1 - 0.72 9.8 3.5 0.63 10.0 0.2 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Cyt_bd_oxida_II PF02322.15 KXX80086.1 - 0.015 14.6 3.6 0.025 14.0 3.6 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II PRA1 PF03208.19 KXX80086.1 - 2.1 8.0 5.3 2.2 7.9 1.9 2.1 2 0 0 2 2 2 0 PRA1 family protein WH2 PF02205.20 KXX80088.1 - 1.8e-10 40.3 0.3 4.5e-10 39.0 0.3 1.7 1 0 0 1 1 1 1 WH2 motif LSM PF01423.22 KXX80090.1 - 5.4e-15 54.8 0.1 6.6e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain HpcH_HpaI PF03328.14 KXX80091.1 - 5.8e-30 104.1 0.0 7.6e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 KXX80091.1 - 0.024 14.1 0.7 9.8 5.5 0.0 3.0 3 1 0 3 3 3 0 Phosphoenolpyruvate phosphomutase DUF3726 PF12525.8 KXX80091.1 - 0.059 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) DUF836 PF05768.14 KXX80092.1 - 2.1e-12 47.3 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KXX80092.1 - 0.0058 16.8 0.1 0.026 14.7 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KXX80092.1 - 0.063 13.1 0.3 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein CHORD PF04968.12 KXX80093.1 - 9.1e-49 164.0 21.0 4.8e-26 91.3 6.3 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KXX80093.1 - 3.4e-14 53.6 0.0 5.5e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 CS domain SMN PF06003.12 KXX80093.1 - 1.5 8.0 8.0 2.5 7.3 8.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RRM_1 PF00076.22 KXX80094.1 - 4.5e-39 132.1 0.0 9.2e-20 70.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXX80094.1 - 0.024 14.6 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CDC45 PF02724.14 KXX80094.1 - 0.029 12.7 12.4 0.032 12.5 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SET_assoc PF11767.8 KXX80094.1 - 0.033 13.8 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated SDA1 PF05285.12 KXX80094.1 - 0.051 13.0 19.2 0.073 12.5 19.2 1.4 1 0 0 1 1 1 0 SDA1 RRM_occluded PF16842.5 KXX80094.1 - 0.12 12.2 0.3 0.33 10.8 0.0 1.9 2 0 0 2 2 1 0 Occluded RNA-recognition motif Apt1 PF10351.9 KXX80094.1 - 0.18 10.6 9.3 0.21 10.4 9.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRM_Rrp7 PF17799.1 KXX80094.1 - 0.35 10.6 3.1 2.2 8.1 0.0 2.7 3 1 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Presenilin PF01080.17 KXX80094.1 - 0.41 9.4 10.2 0.53 9.0 10.2 1.1 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 KXX80094.1 - 0.58 9.8 25.9 1 9.0 25.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zip PF02535.22 KXX80094.1 - 1.6 7.9 7.3 2.1 7.5 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 KXX80094.1 - 2 6.9 9.3 2 6.8 9.3 1.1 1 0 0 1 1 1 0 Macoilin family Merozoite_SPAM PF07133.11 KXX80094.1 - 3.3 7.7 23.9 5.2 7.0 23.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) AF-4 PF05110.13 KXX80094.1 - 9.6 4.1 25.2 13 3.7 25.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NOA36 PF06524.12 KXX80094.1 - 10 5.4 12.2 15 4.8 12.2 1.4 1 0 0 1 1 1 0 NOA36 protein NDUFB10 PF10249.9 KXX80095.1 - 0.011 16.2 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 KXX80095.1 - 0.081 13.6 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase CBFD_NFYB_HMF PF00808.23 KXX80096.1 - 5.3e-09 36.2 0.0 8.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXX80096.1 - 5.8e-05 23.5 0.0 5.8e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXX80096.1 - 0.0022 18.1 0.0 0.0046 17.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PPP4R2 PF09184.11 KXX80096.1 - 0.17 11.5 18.8 0.24 11.0 18.8 1.3 1 0 0 1 1 1 0 PPP4R2 Cadherin_C_2 PF16492.5 KXX80097.1 - 0.15 12.9 0.1 0.79 10.5 0.0 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Saf_2TM PF18303.1 KXX80097.1 - 0.21 11.2 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain TMEM154 PF15102.6 KXX80097.1 - 0.26 11.2 0.0 0.87 9.5 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Spc7_N PF15402.6 KXX80098.1 - 1.5e-215 718.5 75.8 1.4e-131 440.7 22.3 3.2 1 1 2 3 3 3 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KXX80098.1 - 2.1e-126 421.0 7.0 2.1e-126 421.0 7.0 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KXX80098.1 - 3.2e-19 68.8 1.9 5.9e-19 67.9 1.9 1.5 1 0 0 1 1 1 1 Spc7_C2 Ribosomal_S17_N PF16205.5 KXX80099.1 - 6.2e-34 116.2 0.6 1e-33 115.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KXX80099.1 - 2.1e-27 95.0 0.4 4.5e-27 94.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 RRM_1 PF00076.22 KXX80100.1 - 2e-17 62.8 0.0 3e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWI-SNF_Ssr4 PF08549.10 KXX80101.1 - 8.8e-288 956.9 1.0 1e-287 956.7 1.0 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.19 KXX80102.1 - 1.2e-127 425.3 0.0 1.5e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXX80102.1 - 1.2e-50 171.8 0.0 1.9e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXX80102.1 - 0.097 12.9 0.2 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TAFII55_N PF04658.13 KXX80103.1 - 1.3e-50 171.2 0.0 2.5e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Rho_Binding PF08912.11 KXX80103.1 - 0.17 12.7 0.1 0.17 12.7 0.1 2.4 2 1 0 2 2 2 0 Rho Binding RPN2_C PF18004.1 KXX80103.1 - 2.4 8.1 7.6 0.13 12.2 0.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ribosomal_L37 PF08561.10 KXX80104.1 - 2e-41 141.3 1.4 2e-41 141.3 1.4 1.4 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L37 FXR_C1 PF16096.5 KXX80104.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Glyco_hydro_15 PF00723.21 KXX80105.1 - 1e-51 176.1 0.0 1.8e-49 168.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 IU_nuc_hydro PF01156.19 KXX80106.1 - 4.5e-58 197.2 0.0 7.8e-58 196.4 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HLH PF00010.26 KXX80109.1 - 4.7e-13 48.9 0.4 8.4e-13 48.1 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aldedh PF00171.22 KXX80110.1 - 3.4e-109 365.4 0.0 4.3e-109 365.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phage_TAC_7 PF10109.9 KXX80111.1 - 0.0058 16.7 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 PVL_ORF50 PF07768.11 KXX80112.1 - 0.039 14.3 1.8 0.13 12.6 1.8 1.8 1 0 0 1 1 1 0 PVL ORF-50-like family MID_pPIWI_RE PF18157.1 KXX80113.1 - 0.14 12.5 1.6 2.1 8.6 0.0 2.6 3 0 0 3 3 3 0 MID domain of pPIWI_RE Rhomboid PF01694.22 KXX80114.1 - 2.7e-24 85.9 7.6 5.1e-24 85.0 7.6 1.4 1 0 0 1 1 1 1 Rhomboid family PhoD PF09423.10 KXX80115.1 - 0.00047 19.3 0.1 0.02 13.9 0.0 2.5 3 0 0 3 3 3 2 PhoD-like phosphatase Dehydrin PF00257.19 KXX80115.1 - 0.0095 16.5 4.9 0.018 15.6 4.9 1.4 1 0 0 1 1 1 1 Dehydrin TPT PF03151.16 KXX80116.1 - 3.8e-21 75.7 14.3 4.7e-21 75.4 14.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXX80116.1 - 1.4e-05 25.2 35.7 0.00056 20.1 5.6 3.0 2 1 1 3 3 3 2 EamA-like transporter family Phage_holin_2_1 PF04971.12 KXX80116.1 - 0.089 12.8 1.7 1.8 8.6 0.4 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S Bromo_TP PF07524.13 KXX80117.1 - 4.7e-06 26.5 0.0 1.8e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 KXX80117.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-GRF PF06839.12 KXX80118.1 - 2.7e-07 30.6 6.7 5e-07 29.7 6.7 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF416 PF04222.12 KXX80118.1 - 0.12 11.8 0.3 0.22 10.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) MGTL PF17059.5 KXX80118.1 - 1.5 8.7 4.6 1.6 8.6 0.2 2.7 2 0 0 2 2 2 0 MgtA leader peptide ELMO_CED12 PF04727.13 KXX80119.1 - 1e-50 172.3 0.0 3.5e-50 170.6 0.0 1.8 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 KXX80119.1 - 8.4e-37 126.7 0.0 6.1e-36 123.9 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain DUF3361 PF11841.8 KXX80119.1 - 1.2e-12 48.0 0.0 7.6e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) FAD_binding_4 PF01565.23 KXX80120.1 - 3.5e-16 59.2 0.0 6.9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain CRT10 PF08728.10 KXX80121.1 - 1e-17 63.7 0.0 3.4e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 CRT10 His_Phos_2 PF00328.22 KXX80122.1 - 2.9e-48 165.1 0.0 3.5e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mtf2_C PF14061.6 KXX80122.1 - 0.12 12.6 0.6 0.26 11.5 0.6 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 PTPA PF03095.15 KXX80123.1 - 2.7e-112 375.1 0.0 3.1e-112 374.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein NAD_kinase PF01513.21 KXX80125.1 - 6.7e-81 271.7 0.0 1e-80 271.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Glyco_transf_28 PF03033.20 KXX80126.1 - 6.6e-22 78.0 0.0 7.8e-21 74.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXX80126.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXX80126.1 - 0.00063 19.7 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain KR PF08659.10 KXX80127.1 - 2.4e-59 200.3 0.1 4.1e-59 199.5 0.1 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 KXX80127.1 - 1.8e-11 45.2 0.0 5.9e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXX80127.1 - 3e-10 39.9 0.0 8.5e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KXX80127.1 - 3.8e-10 39.8 0.0 8.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KXX80127.1 - 1.7e-05 25.0 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KXX80127.1 - 2.3e-05 24.1 0.0 7.2e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KXX80127.1 - 0.00068 19.5 0.1 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PDZ PF00595.24 KXX80127.1 - 0.088 13.2 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Phage_Coat_A PF05357.13 KXX80127.1 - 0.2 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Phage Coat Protein A Zn_clus PF00172.18 KXX80128.1 - 0.0077 16.3 7.1 0.016 15.3 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KXX80129.1 - 1e-30 107.5 0.1 1.3e-30 107.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXX80129.1 - 0.01 15.0 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 CsiD 7tm_2 PF00002.24 KXX80130.1 - 6.3e-08 32.2 11.8 6.3e-08 32.2 11.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KXX80130.1 - 0.031 13.4 4.2 0.055 12.6 4.2 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Git3 PF11710.8 KXX80130.1 - 0.85 9.3 9.0 4.4 7.0 9.0 2.1 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Cellulase PF00150.18 KXX80131.1 - 5.8e-40 137.5 0.1 6.8e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pcc1 PF09341.10 KXX80132.1 - 5.3e-30 103.4 2.2 6.5e-30 103.1 2.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 KXX80133.1 - 1.7e-41 141.9 0.0 8.3e-39 133.2 0.0 2.8 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KXX80133.1 - 3.3e-17 62.6 0.0 6e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXX80133.1 - 2e-06 27.6 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KXX80133.1 - 0.055 13.6 0.4 0.18 11.9 0.0 2.0 3 0 0 3 3 3 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 KXX80133.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family SWIM PF04434.17 KXX80134.1 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger Pkinase_Tyr PF07714.17 KXX80135.1 - 1.2e-06 28.0 0.0 1.6e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXX80135.1 - 6.9e-05 22.3 0.0 0.00016 21.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain RNase_PH PF01138.21 KXX80136.1 - 1.8e-14 54.4 0.1 3e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXX80136.1 - 0.016 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 WD40 PF00400.32 KXX80137.1 - 2.9e-49 164.0 25.9 2.9e-09 37.4 0.5 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX80137.1 - 8.2e-20 70.9 0.0 0.00085 19.6 0.0 6.2 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX80137.1 - 6.3e-07 28.4 1.7 0.055 12.1 0.2 4.2 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KXX80137.1 - 5.6e-06 26.4 0.0 0.00069 19.5 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXX80137.1 - 1.4e-05 24.2 1.1 0.58 9.1 0.0 4.8 3 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KXX80137.1 - 0.00067 18.5 0.1 1.3 7.7 0.0 3.2 2 1 1 3 3 3 1 Nup133 N terminal like VID27 PF08553.10 KXX80137.1 - 0.026 13.6 0.0 3.3 6.7 0.0 3.5 4 1 1 5 5 5 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 KXX80137.1 - 0.041 13.8 0.1 3.6 7.6 0.1 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KXX80137.1 - 0.074 11.4 0.0 0.98 7.7 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KXX80137.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Exo_endo_phos PF03372.23 KXX80138.1 - 9.3e-15 54.8 0.0 1.5e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Oxysterol_BP PF01237.18 KXX80140.1 - 1.6e-91 306.9 0.0 4.2e-89 299.0 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Abhydrolase_1 PF00561.20 KXX80141.1 - 5.1e-12 46.0 0.0 1.8e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX80141.1 - 2.4e-11 43.4 0.0 4.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXX80141.1 - 4.9e-09 37.1 8.6 4.9e-09 37.1 8.6 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KXX80141.1 - 0.0016 18.6 0.0 0.0036 17.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 KXX80141.1 - 0.036 14.0 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 KXX80141.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Melittin PF01372.17 KXX80141.1 - 0.15 12.1 0.1 0.49 10.4 0.1 1.9 1 0 0 1 1 1 0 Melittin Ammonium_transp PF00909.21 KXX80142.1 - 3.5e-114 381.6 28.7 4e-114 381.4 28.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family C2 PF00168.30 KXX80143.1 - 1.1e-90 298.7 0.3 1.7e-23 82.9 0.0 5.6 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KXX80143.1 - 0.00029 20.3 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 KXX80143.1 - 0.036 13.8 0.2 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins MLVIN_C PF18697.1 KXX80143.1 - 0.066 13.3 0.1 2.7 8.1 0.1 2.9 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain FKBP_C PF00254.28 KXX80143.1 - 0.12 12.7 0.1 1 9.7 0.0 2.6 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase zf-CCCH PF00642.24 KXX80144.1 - 2.8e-08 33.4 20.0 2.9e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXX80144.1 - 0.0057 16.7 3.3 0.0057 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain RRM_1 PF00076.22 KXX80144.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KXX80144.1 - 0.015 16.0 3.4 0.48 11.1 0.2 2.4 2 0 0 2 2 2 0 Torus domain SCRG1 PF15224.6 KXX80144.1 - 0.12 12.5 3.4 0.17 12.0 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 KXX80144.1 - 0.17 12.1 4.6 0.21 11.8 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Homeodomain PF00046.29 KXX80145.1 - 1e-13 50.9 1.4 2.1e-13 49.9 1.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXX80145.1 - 0.15 12.0 0.3 0.31 11.0 0.3 1.5 1 0 0 1 1 1 0 Homeobox KN domain NPL PF17800.1 KXX80146.1 - 2.3e-32 111.7 4.6 1.6e-31 109.0 4.6 2.4 1 1 0 1 1 1 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KXX80146.1 - 1.4e-31 108.7 0.1 1.1e-30 105.8 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 KXX80146.1 - 2e-18 66.7 0.0 2.9e-17 62.9 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80146.1 - 1.5e-06 27.7 0.4 3.1e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase OCC1 PF15506.6 KXX80146.1 - 4 7.6 6.4 13 6.0 0.1 3.3 2 0 0 2 2 2 0 OCC1 family CCDC-167 PF15188.6 KXX80146.1 - 5.5 7.4 7.0 3.4 8.1 4.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TT_ORF2 PF02957.15 KXX80147.1 - 4.3 8.3 6.5 1.1 10.1 0.1 2.5 3 0 0 3 3 3 0 TT viral ORF2 UDPGP PF01704.18 KXX80148.1 - 4.1e-54 183.8 0.0 5.5e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KXX80148.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain YhcG_C PF06250.11 KXX80148.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 YhcG PDDEXK nuclease domain HSP70 PF00012.20 KXX80151.1 - 3.3e-151 504.4 2.5 3.9e-151 504.2 2.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXX80151.1 - 3.1e-12 46.0 0.6 4.4e-11 42.2 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KXX80151.1 - 0.012 14.6 2.0 0.015 14.3 0.6 2.0 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain TOBE_3 PF12857.7 KXX80151.1 - 0.053 13.4 0.0 6.7 6.7 0.1 2.3 2 0 0 2 2 2 0 TOBE-like domain DUF1894 PF08979.11 KXX80151.1 - 0.13 12.7 0.1 16 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) Sporozoite_P67 PF05642.11 KXX80152.1 - 0.034 12.2 0.3 0.063 11.4 0.1 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen F-box PF00646.33 KXX80152.1 - 0.25 11.3 1.3 0.28 11.1 0.1 1.6 2 0 0 2 2 2 0 F-box domain HVSL PF09749.9 KXX80153.1 - 8e-77 257.9 0.0 1.5e-76 257.1 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised conserved protein AbiTii PF18864.1 KXX80153.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 AbiTii Apt1 PF10351.9 KXX80153.1 - 0.19 10.5 1.5 0.23 10.3 1.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KXX80153.1 - 1.2 7.6 5.8 1.6 7.2 5.8 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 KXX80153.1 - 1.2 9.0 10.8 1.9 8.3 10.8 1.5 1 1 0 1 1 1 0 SPX domain CCDC106 PF15794.5 KXX80153.1 - 2.1 8.0 3.3 3.2 7.4 3.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AF-4 PF05110.13 KXX80153.1 - 7 4.6 17.4 9.9 4.1 17.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pal1 PF08316.11 KXX80154.1 - 6.1e-11 43.2 0.1 1.4e-10 42.0 0.1 1.8 1 1 0 1 1 1 1 Pal1 cell morphology protein DUF3682 PF12446.8 KXX80154.1 - 0.026 15.0 1.3 0.026 15.0 1.3 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3682) PRIMA1 PF16101.5 KXX80154.1 - 7.6 6.6 13.0 0.75 9.8 3.4 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CPSF_A PF03178.15 KXX80155.1 - 9.4e-93 311.0 0.0 2e-92 310.0 0.0 1.5 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KXX80155.1 - 8.3e-15 54.4 0.0 3.6e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 KXX80156.1 - 3e-17 62.7 17.4 1.9e-15 56.8 15.2 2.6 2 1 0 2 2 2 1 LMBR1-like membrane protein UDG PF03167.19 KXX80157.1 - 6e-23 81.6 0.1 2.3e-22 79.7 0.0 2.0 2 1 0 2 2 2 1 Uracil DNA glycosylase superfamily ORC6 PF05460.13 KXX80157.1 - 3.6 6.8 6.3 6 6.0 6.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CytochromB561_N PF09786.9 KXX80157.1 - 9 5.2 6.6 11 4.9 6.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mpv17_PMP22 PF04117.12 KXX80158.1 - 1.1e-23 83.2 0.9 1.7e-23 82.6 0.9 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family ubiquitin PF00240.23 KXX80159.1 - 1.6e-17 63.0 0.1 2.3e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KXX80159.1 - 2.7e-07 30.4 0.4 1.2e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.9 KXX80159.1 - 0.0008 19.9 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXX80159.1 - 0.0071 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 KXX80159.1 - 0.026 14.3 0.2 0.04 13.7 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 KXX80159.1 - 0.081 12.9 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_4 PF18036.1 KXX80159.1 - 0.15 12.1 0.6 14 5.8 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain STI1 PF17830.1 KXX80159.1 - 0.25 11.3 4.2 2 8.4 0.5 2.8 1 1 1 2 2 2 0 STI1 domain G-patch PF01585.23 KXX80161.1 - 0.036 14.0 0.8 0.13 12.2 0.8 2.0 1 1 0 1 1 1 0 G-patch domain SRP-alpha_N PF04086.13 KXX80161.1 - 0.45 10.4 19.2 0.8 9.6 19.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hox9_act PF04617.13 KXX80161.1 - 0.67 10.7 4.8 0.92 10.2 4.8 1.2 1 0 0 1 1 1 0 Hox9 activation region Borrelia_P83 PF05262.11 KXX80161.1 - 0.95 7.9 13.3 1.2 7.6 13.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop53 PF07767.11 KXX80161.1 - 2.5 7.4 30.8 3.4 6.9 30.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PA26 PF04636.13 KXX80161.1 - 3.6 6.4 7.3 5 5.9 7.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) AAA_11 PF13086.6 KXX80161.1 - 4.8 6.9 12.9 6.8 6.4 12.9 1.2 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 KXX80161.1 - 6.9 6.6 5.5 9.3 6.2 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Bromodomain PF00439.25 KXX80162.1 - 3e-33 113.7 0.7 3.6e-15 55.8 0.0 2.4 2 0 0 2 2 2 2 Bromodomain BUD22 PF09073.10 KXX80162.1 - 0.0017 17.7 14.3 0.0028 17.1 14.3 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 KXX80162.1 - 0.0085 14.4 15.7 0.013 13.7 15.7 1.3 1 0 0 1 1 1 1 Nop14-like family DARPP-32 PF05395.12 KXX80162.1 - 0.026 14.8 8.9 0.12 12.6 9.5 1.8 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 CDC45 PF02724.14 KXX80162.1 - 0.14 10.4 13.5 0.23 9.7 13.5 1.3 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 KXX80162.1 - 0.15 11.5 16.3 0.23 10.8 16.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Merozoite_SPAM PF07133.11 KXX80162.1 - 3.6 7.5 28.7 6.2 6.8 28.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) NOA36 PF06524.12 KXX80162.1 - 5.9 6.1 22.4 9.6 5.4 22.4 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KXX80162.1 - 6.1 4.8 30.2 9.7 4.2 30.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 KXX80162.1 - 7.6 6.2 7.5 19 5.0 7.5 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Spore_coat_CotO PF14153.6 KXX80162.1 - 7.8 6.4 11.6 14 5.6 11.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_Rpb1_1 PF04997.12 KXX80164.1 - 5.1e-106 354.5 0.0 8e-106 353.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXX80164.1 - 7.5e-100 333.8 0.1 1.6e-99 332.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXX80164.1 - 2.9e-77 258.6 0.0 6e-77 257.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KXX80164.1 - 1.3e-64 217.5 3.0 2.5e-64 216.7 3.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KXX80164.1 - 3.7e-46 156.9 0.0 1.2e-45 155.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KXX80164.1 - 8.6e-44 148.8 4.4 2.6e-43 147.2 4.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KXX80164.1 - 9.3e-37 125.3 0.1 2.4e-36 124.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KXX80164.1 - 0.01 16.1 8.9 0.01 16.1 8.9 14.6 10 4 6 16 16 16 0 RNA polymerase Rpb1 C-terminal repeat zf-C4pol PF14260.6 KXX80164.1 - 0.38 11.2 1.2 0.97 9.9 1.2 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Thg1 PF04446.12 KXX80166.1 - 1.7e-54 183.1 0.0 2.6e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KXX80166.1 - 1.6e-50 170.4 0.2 2.3e-50 169.8 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain WD40 PF00400.32 KXX80167.1 - 1.4e-16 60.6 5.1 1.3e-05 25.9 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX80167.1 - 1e-11 44.9 1.3 0.00056 20.1 0.0 5.3 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXX80167.1 - 9.4e-05 22.4 0.0 0.092 12.6 0.0 3.2 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KXX80167.1 - 0.065 12.8 0.2 0.58 9.7 0.0 2.4 3 1 0 3 3 3 0 PQQ-like domain ERO1 PF04137.15 KXX80168.1 - 9.8e-134 446.0 0.5 2.9e-133 444.5 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RPA_interact_N PF14766.6 KXX80168.1 - 0.23 11.1 1.9 7 6.4 0.0 3.2 4 0 0 4 4 4 0 Replication protein A interacting N-terminal CKS PF01111.19 KXX80169.1 - 3.1e-33 113.8 0.7 4.2e-33 113.4 0.7 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit AMP-binding PF00501.28 KXX80170.1 - 1.2e-70 238.3 0.0 2.5e-70 237.2 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX80170.1 - 1.7e-11 44.9 0.2 3.2e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 KXX80171.1 - 5.6e-56 188.7 0.2 7.1e-56 188.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E BolA PF01722.18 KXX80172.1 - 2.2e-30 104.8 0.4 2.6e-30 104.5 0.4 1.1 1 0 0 1 1 1 1 BolA-like protein PIP5K PF01504.18 KXX80174.1 - 2e-32 112.5 4.8 2.4e-25 89.3 0.8 2.8 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KXX80174.1 - 5.7e-27 94.5 0.0 9.3e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KXX80174.1 - 3.3e-13 49.6 11.0 3.3e-13 49.6 11.0 1.9 2 0 0 2 2 2 1 FYVE zinc finger FF PF01846.19 KXX80174.1 - 0.038 14.2 0.0 5.4 7.3 0.0 3.0 2 0 0 2 2 2 0 FF domain AvrM_N PF18247.1 KXX80174.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain LHH PF14411.6 KXX80174.1 - 0.16 12.1 0.4 0.61 10.3 0.4 2.0 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH FYVE_2 PF02318.16 KXX80174.1 - 2.3 8.4 10.0 0.3 11.3 4.9 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger C1_1 PF00130.22 KXX80174.1 - 6.5 6.7 14.3 18 5.3 9.1 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cyclin_N PF00134.23 KXX80175.1 - 3.3e-40 136.8 0.5 1.2e-39 134.9 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXX80175.1 - 3.4e-11 43.3 0.1 1.1e-10 41.6 0.1 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain Myosin_head PF00063.21 KXX80176.1 - 1.1e-238 793.9 4.2 1.3e-238 793.6 4.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KXX80176.1 - 2.6e-48 164.2 0.0 4.6e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KXX80176.1 - 4.5e-12 45.4 0.2 8.3e-12 44.5 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX80176.1 - 2.2e-07 30.6 0.0 5.7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX80176.1 - 8.2e-06 25.4 0.0 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KXX80176.1 - 0.0032 17.1 10.7 0.16 11.8 2.3 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 KXX80176.1 - 0.01 15.3 0.2 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KXX80176.1 - 0.037 14.3 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX80176.1 - 0.1 13.0 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KXX80176.1 - 0.13 12.2 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain SepF PF04472.12 KXX80176.1 - 0.14 12.4 0.0 0.47 10.8 0.0 1.8 1 0 0 1 1 1 0 Cell division protein SepF DUF4913 PF16259.5 KXX80176.1 - 0.25 11.4 1.5 0.66 10.1 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) DHHC PF01529.20 KXX80178.1 - 1.6e-33 115.7 0.2 1.6e-33 115.7 0.2 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Glyco_transf_90 PF05686.12 KXX80179.1 - 2e-09 36.9 0.3 0.0074 15.2 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 Lactamase_B PF00753.27 KXX80180.1 - 1.2e-06 28.7 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_18 PF00704.28 KXX80181.1 - 6.4e-63 213.3 0.0 7.5e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Calpain_inhib PF00748.19 KXX80182.1 - 0.053 14.0 1.2 0.053 14.0 1.2 3.2 2 2 1 3 3 3 0 Calpain inhibitor Pec_lyase_C PF00544.19 KXX80183.1 - 3.2e-38 131.4 8.9 4.4e-38 131.0 8.9 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXX80183.1 - 2e-05 24.5 10.1 0.00052 19.9 9.9 2.3 1 1 0 1 1 1 1 Right handed beta helix region DUF3614 PF12267.8 KXX80183.1 - 0.04 14.4 0.0 0.061 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) AAA_16 PF13191.6 KXX80184.1 - 4.5e-05 23.9 0.0 0.00015 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXX80184.1 - 4.8e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF829 PF05705.14 KXX80184.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PGAP1 PF07819.13 KXX80184.1 - 0.0019 17.9 0.0 0.005 16.6 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KXX80184.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KXX80184.1 - 0.014 16.0 0.1 0.045 14.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA_22 PF13401.6 KXX80184.1 - 0.044 14.1 0.4 1.3 9.3 0.0 3.0 1 1 1 2 2 2 0 AAA domain CYSTM PF12734.7 KXX80184.1 - 0.047 14.0 2.9 0.13 12.6 2.9 1.7 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF1664 PF07889.12 KXX80185.1 - 0.33 11.0 1.4 0.73 9.9 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KXX80185.1 - 0.34 11.0 3.1 0.13 12.3 0.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KXX80185.1 - 1.8 8.6 6.6 5.2 7.1 0.0 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 KXX80185.1 - 5.5 7.1 7.9 1.7 8.8 0.1 3.3 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KXX80186.1 - 0.0039 17.3 4.0 0.0039 17.3 4.0 5.6 2 2 3 5 5 5 1 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 KXX80186.1 - 0.0046 17.2 2.8 0.0046 17.2 2.8 7.9 1 1 6 8 8 8 2 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 KXX80186.1 - 0.8 10.0 8.4 8.6 6.7 0.2 3.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KXX80186.1 - 2.3 8.7 8.1 2.5 8.6 0.0 3.9 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein EDR1 PF14381.6 KXX80186.1 - 6.6 6.4 8.1 5.7 6.6 4.0 2.7 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 Vps54 PF07928.12 KXX80186.1 - 8.1 6.9 0.0 8.1 6.9 0.0 3.8 4 1 1 5 5 5 0 Vps54-like protein DUF3292 PF11696.8 KXX80187.1 - 1.7e-284 945.3 0.0 1.9e-284 945.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PMI_typeI PF01238.21 KXX80188.1 - 3e-77 260.3 0.0 2.7e-76 257.2 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KXX80188.1 - 3.4e-06 26.7 0.3 0.0021 17.8 0.3 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KXX80188.1 - 1.3e-05 25.1 0.0 0.0014 18.6 0.0 2.3 1 1 1 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KXX80188.1 - 0.012 15.3 0.4 0.041 13.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) AraC_binding_2 PF14525.6 KXX80188.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AraC-binding-like domain SET PF00856.28 KXX80189.1 - 0.00063 20.2 0.8 0.0066 16.9 0.8 2.3 1 1 0 1 1 1 1 SET domain TPR_MalT PF17874.1 KXX80189.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region Ribosomal_60s PF00428.19 KXX80189.1 - 0.028 15.0 13.6 0.082 13.5 13.6 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Noelin-1 PF12308.8 KXX80189.1 - 0.031 14.3 0.0 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein TPR_2 PF07719.17 KXX80189.1 - 0.047 13.8 2.5 1.8 8.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SAF PF08666.12 KXX80189.1 - 0.1 13.2 0.0 20 5.9 0.0 2.4 2 0 0 2 2 2 0 SAF domain RPN2_C PF18004.1 KXX80189.1 - 0.15 12.0 2.9 0.29 11.0 2.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Myc_N PF01056.18 KXX80189.1 - 0.19 11.6 2.2 0.29 11.0 2.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TPR_1 PF00515.28 KXX80189.1 - 0.26 11.2 0.9 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 KXX80189.1 - 0.85 7.6 5.0 1.2 7.2 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi NARP1 PF12569.8 KXX80189.1 - 4.3 6.1 6.2 20 3.9 0.1 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Glyco_hydro_30 PF02055.16 KXX80190.1 - 0.046 12.7 0.0 0.89 8.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain An_peroxidase PF03098.15 KXX80191.1 - 2.4e-12 46.2 0.0 3.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Oxidored_molyb PF00174.19 KXX80192.1 - 1.9e-49 167.6 0.0 5.8e-49 166.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXX80192.1 - 8e-38 129.6 1.2 1.6e-37 128.6 1.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KXX80192.1 - 8.9e-22 77.8 0.1 5.4e-21 75.3 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXX80192.1 - 5.4e-18 65.2 0.0 7.9e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KXX80192.1 - 8.3e-17 61.1 0.2 2e-16 59.9 0.2 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXX80192.1 - 0.086 13.0 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Aldo_ket_red PF00248.21 KXX80193.1 - 9.2e-65 218.7 0.0 1.1e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_3 PF07969.11 KXX80196.1 - 8e-18 65.1 1.3 1.2e-10 41.5 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 KXX80196.1 - 2.2e-12 47.0 0.0 8.8e-09 35.1 0.0 3.3 2 1 0 2 2 2 2 Amidohydrolase family DUF2717 PF10911.8 KXX80197.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Ribosomal_L21e PF01157.18 KXX80198.1 - 0.06 13.2 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L21e Fungal_trans PF04082.18 KXX80199.1 - 1.8e-20 73.1 0.1 2.5e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF202 PF02656.15 KXX80200.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Yip1 PF04893.17 KXX80200.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.20 KXX80200.1 - 0.25 11.3 0.5 0.43 10.5 0.5 1.3 1 0 0 1 1 1 0 Syndecan domain An_peroxidase PF03098.15 KXX80202.1 - 2.1e-26 92.6 0.0 5.7e-11 41.7 0.1 3.1 1 1 1 2 2 2 2 Animal haem peroxidase zf-C2H2_assoc PF16606.5 KXX80202.1 - 0.037 14.2 2.8 0.055 13.7 1.7 1.8 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF2235 PF09994.9 KXX80203.1 - 4.3e-96 321.6 0.2 5.5e-96 321.3 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 KXX80203.1 - 0.078 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Peptidase_C97 PF05903.14 KXX80204.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain CLASP_N PF12348.8 KXX80204.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 CLASP N terminal Zincin_2 PF10103.9 KXX80204.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Zincin-like metallopeptidase TPR_12 PF13424.6 KXX80207.1 - 3.4e-11 43.3 18.0 9.1e-05 22.7 4.6 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXX80207.1 - 5.8e-09 36.0 17.0 0.047 14.5 0.4 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX80207.1 - 1.3e-05 24.8 12.6 0.00086 18.8 7.9 2.3 1 1 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 KXX80207.1 - 3.3e-05 23.6 16.8 0.0038 17.0 0.6 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat HET PF06985.11 KXX80207.1 - 4.7e-05 23.8 0.0 0.0028 18.0 0.0 2.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_19 PF14559.6 KXX80207.1 - 6.3e-05 23.4 11.7 0.022 15.2 0.0 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX80207.1 - 0.0052 16.8 11.2 0.26 11.5 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX80207.1 - 0.025 14.6 0.3 2.2 8.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXX80207.1 - 0.99 10.2 22.8 4 8.4 3.8 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.13 KXX80207.1 - 1.3 9.3 6.0 6.1 7.1 1.2 2.7 2 0 0 2 2 2 0 HemY protein N-terminus Peptidase_M14 PF00246.24 KXX80208.1 - 4.3e-82 276.2 0.0 5.8e-82 275.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KXX80208.1 - 1e-07 32.2 0.0 1.6e-06 28.4 0.0 2.5 2 1 0 2 2 2 1 Carboxypeptidase activation peptide adh_short PF00106.25 KXX80209.1 - 3.9e-21 75.4 0.0 5.3e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX80209.1 - 3.5e-11 43.1 0.0 5.6e-11 42.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX80209.1 - 6.3e-09 36.0 0.0 8.3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX80209.1 - 9.7e-06 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXX80209.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 KXX80210.1 - 2.2e-53 181.5 0.0 3e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX80210.1 - 9e-31 107.3 0.0 1.4e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXX80210.1 - 3.9e-06 26.2 0.0 7.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXX80210.1 - 9.9e-05 21.6 0.0 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX80210.1 - 0.00039 19.8 0.0 0.0015 17.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX80210.1 - 0.00063 19.4 0.0 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX80210.1 - 0.0013 19.0 0.1 0.0067 16.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXX80210.1 - 0.0014 17.8 0.1 0.13 11.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXX80210.1 - 0.004 16.4 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX80210.1 - 0.0043 15.8 0.0 0.72 8.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KXX80210.1 - 0.2 10.9 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Glyco_hydro_11 PF00457.17 KXX80212.1 - 3e-70 235.5 19.1 3.6e-70 235.2 19.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 PYNP_C PF07831.13 KXX80213.1 - 0.096 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Glyco_hydro_31 PF01055.26 KXX80215.1 - 4.3e-150 500.7 3.4 6.3e-150 500.2 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AA_permease PF00324.21 KXX80215.1 - 4.4e-125 418.0 40.3 5.5e-123 411.1 40.3 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX80215.1 - 5e-34 117.9 35.4 7.3e-34 117.3 35.4 1.2 1 0 0 1 1 1 1 Amino acid permease NtCtMGAM_N PF16863.5 KXX80215.1 - 2.4e-22 79.3 0.3 4.4e-22 78.5 0.3 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXX80215.1 - 2.9e-11 43.5 2.0 3.5e-11 43.2 0.4 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXX80215.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Vma12 PF11712.8 KXX80215.1 - 7.4 6.6 7.4 13 5.8 1.5 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MoCF_biosynth PF00994.24 KXX80216.1 - 6.5e-30 103.7 0.0 3e-29 101.5 0.0 1.9 2 1 0 2 2 2 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 KXX80217.1 - 4.9e-20 71.6 0.0 5.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Csm1 PF12539.8 KXX80217.1 - 0.082 13.6 0.6 0.19 12.3 0.4 1.7 1 1 1 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 ParA PF10609.9 KXX80218.1 - 2e-96 322.2 0.0 2.4e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXX80218.1 - 7.2e-09 35.8 0.0 2.9e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXX80218.1 - 1.1e-05 25.4 0.1 6.4e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KXX80218.1 - 1.8e-05 24.1 0.5 0.00025 20.3 0.1 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KXX80218.1 - 0.001 18.7 0.3 0.0019 17.8 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KXX80218.1 - 0.0012 18.7 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXX80218.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 KXX80218.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 KXX80218.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Fer4_NifH PF00142.18 KXX80218.1 - 0.0054 16.2 0.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 KXX80218.1 - 0.0068 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXX80218.1 - 0.0068 16.8 0.0 0.01 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain CBP_BcsQ PF06564.12 KXX80218.1 - 0.0071 15.9 0.1 0.079 12.4 0.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 KXX80218.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Ras PF00071.22 KXX80218.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Ras family RNA_helicase PF00910.22 KXX80218.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KXX80218.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 KXX80218.1 - 0.075 12.2 0.2 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 KXX80218.1 - 0.084 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXX80218.1 - 0.085 12.9 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KXX80218.1 - 0.085 12.9 0.1 6.1 7.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KXX80218.1 - 0.089 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 KXX80218.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KXX80218.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KXX80218.1 - 0.25 11.4 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ECM11 PF15463.6 KXX80219.1 - 1.2e-46 158.6 0.8 1.2e-46 158.6 0.8 2.4 2 1 1 3 3 3 1 Extracellular mutant protein 11 DUF3915 PF13054.6 KXX80219.1 - 0.28 11.2 7.3 0.6 10.1 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SRP54 PF00448.22 KXX80220.1 - 4.6e-07 29.7 0.0 6.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRK PF00485.18 KXX80220.1 - 4.9e-05 23.2 0.0 0.00011 22.0 0.0 1.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 KXX80220.1 - 0.00023 20.3 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXX80220.1 - 0.00024 21.5 0.1 0.0005 20.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXX80220.1 - 0.00038 19.8 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KXX80220.1 - 0.00049 20.6 0.0 0.0017 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXX80220.1 - 0.00093 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 KXX80220.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.4 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 KXX80220.1 - 0.0019 17.5 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.29 KXX80220.1 - 0.0022 18.4 0.0 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX80220.1 - 0.0029 17.8 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXX80220.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KXX80220.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXX80220.1 - 0.012 16.1 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXX80220.1 - 0.014 15.6 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KXX80220.1 - 0.015 15.2 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 KXX80220.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KXX80220.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 KXX80220.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 KXX80220.1 - 0.032 13.9 0.4 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 KXX80220.1 - 0.033 14.1 0.2 0.053 13.4 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 KXX80220.1 - 0.048 13.9 0.1 0.11 12.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KXX80220.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KXX80220.1 - 0.077 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LpxK PF02606.14 KXX80220.1 - 0.079 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF815 PF05673.13 KXX80220.1 - 0.085 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ArsA_ATPase PF02374.15 KXX80220.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase APS_kinase PF01583.20 KXX80220.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.6 KXX80220.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXX80220.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 adh_short PF00106.25 KXX80221.1 - 3.4e-86 287.7 11.0 2.1e-45 154.6 0.6 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX80221.1 - 4.2e-67 226.1 7.2 4.5e-35 121.3 0.5 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KXX80221.1 - 3.3e-34 117.1 0.0 6.4e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KXX80221.1 - 4.4e-31 108.2 3.4 4.6e-15 56.0 0.6 2.6 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 KXX80221.1 - 0.00032 20.8 0.0 0.38 10.9 0.0 2.8 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 KXX80221.1 - 0.00047 19.5 1.2 0.0091 15.3 0.6 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KXX80221.1 - 0.005 16.3 3.2 0.15 11.5 0.1 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXX80221.1 - 1.1 9.1 5.8 3.3 7.6 0.8 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 KXX80221.1 - 2.4 8.0 8.0 5.4 6.8 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase Ysc84 PF04366.12 KXX80222.1 - 1.3e-34 118.7 0.0 2.4e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator PAC2 PF09754.9 KXX80222.1 - 0.029 14.4 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 PAC2 family TrkA_TMD PF18613.1 KXX80222.1 - 0.12 11.8 0.8 0.34 10.4 0.8 1.7 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain SasG_E PF17041.5 KXX80223.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 E domain Lactamase_B PF00753.27 KXX80225.1 - 1e-17 64.8 1.8 2.4e-17 63.6 1.8 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXX80225.1 - 0.00092 18.8 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sulf_transp PF04143.14 KXX80226.1 - 8.1e-26 91.3 28.4 1.7e-25 90.2 28.4 1.5 1 1 0 1 1 1 1 Sulphur transport DUF3007 PF11460.8 KXX80226.1 - 0.18 12.1 0.6 0.55 10.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3007) Kelch_5 PF13854.6 KXX80227.1 - 1.9e-13 50.1 8.7 7.8e-13 48.1 0.6 3.8 3 1 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 KXX80227.1 - 4.4e-08 32.6 1.1 0.0066 16.0 0.3 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KXX80227.1 - 4.2e-07 29.9 1.9 0.72 9.9 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXX80227.1 - 0.00043 20.5 11.9 0.0015 18.8 0.3 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXX80227.1 - 0.0044 17.3 4.4 0.031 14.6 0.2 4.0 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 KXX80227.1 - 0.019 14.9 3.2 5.5 7.1 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Plasmodium_Vir PF05795.11 KXX80228.1 - 5 6.4 10.0 0.047 13.1 0.4 2.1 2 1 0 2 2 2 0 Plasmodium vivax Vir protein Vps5 PF09325.10 KXX80229.1 - 1.7e-12 47.4 1.6 2.7e-12 46.8 1.6 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXX80229.1 - 8.9e-09 35.3 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 PX domain NST1 PF13945.6 KXX80229.1 - 0.15 12.2 1.4 0.25 11.4 1.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator GTP_EFTU PF00009.27 KXX80230.1 - 2.2e-54 184.0 0.0 3.4e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXX80230.1 - 9.1e-24 83.4 0.0 2.1e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KXX80230.1 - 1.4e-10 41.1 0.0 0.0009 19.2 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus RF3_C PF16658.5 KXX80230.1 - 0.0041 16.9 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 KXX80230.1 - 0.016 15.5 0.0 0.053 13.9 0.0 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 2 IBR PF01485.21 KXX80231.1 - 7.7e-06 26.0 4.9 7.7e-06 26.0 4.9 5.0 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain Actin PF00022.19 KXX80232.1 - 7.8e-18 64.3 0.0 1.1e-14 53.8 0.0 2.5 3 0 0 3 3 3 2 Actin FtsA PF14450.6 KXX80232.1 - 0.06 13.8 0.1 0.23 11.9 0.1 2.2 1 1 0 1 1 1 0 Cell division protein FtsA Ribonuc_L-PSP PF01042.21 KXX80233.1 - 6e-26 90.8 0.0 7.1e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SMC_Nse1 PF07574.13 KXX80234.1 - 5.4e-65 218.9 0.0 6.7e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KXX80234.1 - 4.4e-15 55.7 10.0 6.6e-15 55.1 10.0 1.3 1 0 0 1 1 1 1 RING-like domain Mrr_N PF14338.6 KXX80234.1 - 0.028 14.5 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Mrr N-terminal domain zf-TAZ PF02135.16 KXX80234.1 - 0.34 11.4 5.7 0.59 10.6 5.7 1.3 1 0 0 1 1 1 0 TAZ zinc finger DZR PF12773.7 KXX80234.1 - 3.4 7.8 6.6 12 6.0 6.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon Sugar_tr PF00083.24 KXX80235.1 - 0.086 11.7 0.0 0.16 10.8 0.0 1.4 2 0 0 2 2 2 0 Sugar (and other) transporter SPRY PF00622.28 KXX80236.1 - 0.00023 21.2 0.0 0.0031 17.6 0.0 2.8 4 0 0 4 4 4 1 SPRY domain Myb_Cef PF11831.8 KXX80237.1 - 4.4e-50 170.5 12.1 4.4e-50 170.5 12.1 2.7 2 1 0 2 2 2 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KXX80237.1 - 1.9e-22 79.2 4.3 8.5e-11 41.9 0.9 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXX80237.1 - 1.3e-20 73.4 6.7 3e-14 53.0 2.5 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KXX80237.1 - 0.046 13.8 2.3 0.11 12.6 0.0 2.9 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.16 KXX80238.1 - 7.7e-07 28.3 6.0 7.7e-07 28.3 6.0 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily TMEM132D_C PF15706.5 KXX80238.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term GILT PF03227.16 KXX80240.1 - 5.6e-19 68.4 0.1 7.8e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) ADH_N PF08240.12 KXX80241.1 - 5e-27 93.9 1.2 1.2e-26 92.7 1.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX80241.1 - 2.5e-14 53.4 2.3 1.7e-13 50.6 2.3 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXX80241.1 - 3.9e-09 36.3 0.9 4.2e-05 23.1 0.1 2.7 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXX80241.1 - 0.013 15.1 0.5 0.04 13.5 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KXX80241.1 - 0.015 16.4 0.0 0.029 15.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KXX80241.1 - 0.026 14.7 0.4 0.083 13.1 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KXX80241.1 - 0.027 13.8 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 KXX80241.1 - 0.03 13.6 0.9 0.056 12.7 0.9 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KXX80241.1 - 0.064 12.5 0.0 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXX80241.1 - 0.097 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_25 PF13649.6 KXX80241.1 - 0.13 13.0 0.3 19 6.0 0.1 2.5 2 0 0 2 2 2 0 Methyltransferase domain Shikimate_DH PF01488.20 KXX80241.1 - 0.16 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KXX80241.1 - 0.33 9.6 0.9 0.47 9.1 0.9 1.2 1 0 0 1 1 1 0 HI0933-like protein MitMem_reg PF13012.6 KXX80242.1 - 3.3e-14 53.2 0.8 6e-14 52.4 0.8 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXX80242.1 - 2e-08 34.2 0.0 5.1e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Utp21 PF04192.12 KXX80243.1 - 4.9e-80 268.4 0.0 6.7e-80 267.9 0.0 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KXX80243.1 - 4.3e-17 62.2 27.3 9e-06 26.3 1.1 10.0 10 1 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX80243.1 - 5.3e-14 52.3 0.0 0.00014 22.1 0.0 5.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX80243.1 - 7.5e-06 24.9 1.1 0.81 8.3 0.0 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KXX80243.1 - 7.8e-05 21.4 0.0 0.00013 20.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KXX80243.1 - 0.032 13.0 0.0 3.7 6.2 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KXX80243.1 - 0.12 11.3 0.5 20 4.0 0.0 3.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 KXX80243.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 His_Phos_2 PF00328.22 KXX80244.1 - 5.3e-109 365.1 0.0 7.2e-109 364.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KXX80244.1 - 9.5e-30 102.6 0.1 1.2e-13 51.1 0.0 2.4 2 0 0 2 2 2 2 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KXX80244.1 - 4.3e-07 29.7 0.0 7.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Roughex PF06020.11 KXX80245.1 - 0.22 10.6 0.6 0.29 10.2 0.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF4023 PF13215.6 KXX80245.1 - 0.65 10.0 3.1 0.61 10.1 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) AA_permease PF00324.21 KXX80246.1 - 2.5e-115 385.8 36.0 3.1e-115 385.5 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX80246.1 - 2.6e-21 76.0 37.5 3.4e-21 75.6 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease CheZ PF04344.13 KXX80247.1 - 0.027 14.4 0.1 0.074 13.0 0.1 1.8 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ CHASE3 PF05227.13 KXX80247.1 - 0.052 13.5 0.1 0.052 13.5 0.1 3.2 4 1 0 4 4 4 0 CHASE3 domain DcpS PF05652.12 KXX80248.1 - 6.8e-37 126.5 0.0 1e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KXX80248.1 - 2.2e-31 108.7 0.0 3.5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Glyco_hydro_76 PF03663.14 KXX80249.1 - 3.6e-46 158.3 11.6 5.1e-46 157.9 11.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXX80249.1 - 3.1e-06 26.5 0.1 0.0035 16.5 0.0 2.3 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KXX80249.1 - 0.014 14.9 0.0 0.17 11.4 0.0 2.3 2 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus TFCD_C PF12612.8 KXX80250.1 - 4.7e-27 95.1 0.2 2.6e-26 92.6 0.1 2.4 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KXX80250.1 - 0.033 14.4 7.8 0.096 13.0 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat RTP1_C1 PF10363.9 KXX80250.1 - 0.062 13.5 0.2 0.33 11.2 0.1 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KXX80250.1 - 0.079 13.4 0.2 0.079 13.4 0.2 5.4 5 1 1 6 6 6 0 HEAT repeats IFRD PF05004.13 KXX80250.1 - 0.079 12.0 3.0 0.19 10.8 0.5 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 KXX80250.1 - 0.16 12.5 3.1 8.8 6.9 0.0 4.9 3 0 0 3 3 3 0 HEAT-like repeat Pyridoxal_deC PF00282.19 KXX80251.1 - 4.6e-101 338.2 0.0 5.9e-101 337.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Anoctamin PF04547.12 KXX80252.1 - 6.3e-111 371.4 14.1 7.9e-111 371.1 14.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel EIF_2_alpha PF07541.12 KXX80253.1 - 4.3e-35 120.3 0.0 8.2e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KXX80253.1 - 8.7e-14 51.6 0.7 1.5e-13 50.8 0.7 1.4 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.29 KXX80254.1 - 1.8e-27 95.2 0.3 8.4e-16 57.8 0.0 6.1 7 0 0 7 7 7 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KXX80254.1 - 2.6e-17 63.7 3.9 3.3e-16 60.1 3.9 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase Mito_carr PF00153.27 KXX80255.1 - 1.3e-61 204.5 2.2 1.5e-21 76.1 0.5 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.23 KXX80256.1 - 1.4e-07 31.3 0.1 4.8e-07 29.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXX80256.1 - 4.1e-05 23.4 0.0 0.0013 18.5 0.0 2.4 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 SE PF08491.10 KXX80257.1 - 5.1e-88 294.7 0.0 7.1e-88 294.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KXX80257.1 - 8.4e-10 38.8 0.8 1e-06 28.6 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXX80257.1 - 1.7e-08 34.1 3.6 1.8e-06 27.4 0.4 2.8 2 1 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KXX80257.1 - 1.6e-06 27.5 2.4 7.8e-05 21.9 0.2 2.5 2 1 1 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXX80257.1 - 2e-05 24.7 0.3 4.5e-05 23.6 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX80257.1 - 6.1e-05 22.3 0.6 0.00013 21.2 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXX80257.1 - 6.8e-05 22.4 0.3 6.8e-05 22.4 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX80257.1 - 0.00046 19.5 0.0 0.00079 18.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXX80257.1 - 0.00079 18.7 0.1 0.0016 17.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX80257.1 - 0.0012 19.4 0.2 0.0026 18.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXX80257.1 - 0.0099 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KXX80257.1 - 0.024 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXX80257.1 - 0.029 13.1 0.1 0.047 12.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KXX80257.1 - 0.03 13.2 0.9 1.6 7.5 0.9 2.5 2 1 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KXX80257.1 - 0.03 14.2 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXX80257.1 - 0.049 13.7 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KXX80257.1 - 0.071 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 KXX80257.1 - 0.072 12.4 0.0 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 ThiF family TPR_14 PF13428.6 KXX80258.1 - 0.0029 18.3 15.2 0.27 12.1 0.0 7.0 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXX80258.1 - 0.0086 16.7 8.0 2.5 8.8 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX80258.1 - 0.011 15.7 0.0 3.2 8.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KXX80258.1 - 0.015 15.5 0.6 79 3.8 0.0 5.1 5 0 0 5 5 5 0 PPR repeat TPR_MalT PF17874.1 KXX80258.1 - 0.03 13.7 1.9 0.15 11.4 0.1 2.8 3 0 0 3 3 3 0 MalT-like TPR region TPR_4 PF07721.14 KXX80258.1 - 0.075 13.7 2.3 1.7 9.5 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXX80258.1 - 0.088 13.3 5.2 0.34 11.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXX80258.1 - 0.14 12.4 1.0 43 4.6 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Rabaptin PF03528.15 KXX80258.1 - 0.43 9.2 2.8 0.65 8.6 2.8 1.1 1 0 0 1 1 1 0 Rabaptin TPR_12 PF13424.6 KXX80258.1 - 1.3 9.4 4.2 11 6.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 KXX80260.1 - 1.2e-22 80.5 0.0 1.9e-18 66.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXX80260.1 - 2.3e-06 27.7 0.0 0.00048 20.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Zn_clus PF00172.18 KXX80262.1 - 2e-06 27.8 10.3 3.3e-06 27.1 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKI PF01202.22 KXX80263.1 - 8.5e-22 78.0 0.0 1.6e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase DHquinase_I PF01487.15 KXX80263.1 - 5.9e-17 62.7 0.0 1.1e-16 61.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KXX80263.1 - 1e-15 57.7 0.1 2e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KXX80263.1 - 7.2e-07 29.4 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KXX80263.1 - 0.00035 20.3 0.1 0.00086 19.0 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain HemY_N PF07219.13 KXX80264.1 - 0.32 11.2 1.2 18 5.6 0.0 2.6 3 0 0 3 3 3 0 HemY protein N-terminus DUF3984 PF13136.6 KXX80264.1 - 1 8.7 5.6 1.6 8.1 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Spt20 PF12090.8 KXX80264.1 - 1.3 8.6 17.7 1.9 8.1 17.7 1.1 1 0 0 1 1 1 0 Spt20 family EIF4E-T PF10477.9 KXX80264.1 - 2.2 7.0 11.0 2.9 6.6 11.0 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E TFIIA PF03153.13 KXX80264.1 - 6.8 6.6 17.6 8.9 6.2 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM76 PF16046.5 KXX80265.1 - 7.7e-10 38.6 13.7 7.7e-10 38.6 13.7 2.2 2 0 0 2 2 2 1 FAM76 protein TFIIA PF03153.13 KXX80265.1 - 2.9e-06 27.6 32.8 4.1e-06 27.1 32.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 KXX80265.1 - 0.00025 20.6 12.1 0.0023 17.4 12.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 KXX80265.1 - 0.00036 21.0 12.6 0.00047 20.6 12.6 1.3 1 0 0 1 1 1 1 Enhancer of polycomb-like Lin-8 PF03353.15 KXX80265.1 - 0.00074 19.2 16.9 0.00086 19.0 16.9 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Pex14_N PF04695.13 KXX80265.1 - 0.0062 17.2 27.2 0.01 16.5 27.2 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 KXX80265.1 - 0.012 14.0 14.4 0.014 13.8 14.4 1.2 1 0 0 1 1 1 0 CDC45-like protein GPCR_chapero_1 PF11904.8 KXX80265.1 - 0.014 14.9 4.9 0.014 14.8 4.9 1.3 1 0 0 1 1 1 0 GPCR-chaperone Neur_chan_memb PF02932.16 KXX80265.1 - 0.014 15.5 9.4 0.019 15.1 9.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 KXX80265.1 - 0.034 13.1 22.1 0.042 12.8 22.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 KXX80265.1 - 0.042 12.7 9.6 0.049 12.5 9.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Tim54 PF11711.8 KXX80265.1 - 0.042 12.6 13.4 0.066 12.0 13.4 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 KXX80265.1 - 0.043 12.1 38.5 0.055 11.7 38.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dsh_C PF12316.8 KXX80265.1 - 0.045 14.2 12.5 0.072 13.5 12.5 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 KXX80265.1 - 0.062 12.1 23.7 0.084 11.6 23.7 1.1 1 0 0 1 1 1 0 Presenilin Asparaginase_2 PF01112.18 KXX80265.1 - 0.063 12.3 4.7 0.085 11.9 4.7 1.4 1 0 0 1 1 1 0 Asparaginase Dicty_REP PF05086.12 KXX80265.1 - 0.07 11.1 6.4 0.086 10.8 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4045 PF13254.6 KXX80265.1 - 0.086 12.5 16.5 0.1 12.2 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Zip PF02535.22 KXX80265.1 - 0.1 11.8 7.0 0.12 11.5 7.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 KXX80265.1 - 0.11 11.0 10.7 0.13 10.7 10.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 KXX80265.1 - 0.12 9.4 16.0 0.14 9.3 16.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 KXX80265.1 - 0.13 11.9 44.5 0.24 11.0 44.5 1.5 1 0 0 1 1 1 0 Spt20 family Bul1_N PF04425.12 KXX80265.1 - 0.13 11.0 8.5 0.15 10.8 8.5 1.2 1 0 0 1 1 1 0 Bul1 N terminus DUF4746 PF15928.5 KXX80265.1 - 0.16 11.4 13.5 0.23 10.9 13.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Plasmodium_Vir PF05795.11 KXX80265.1 - 0.18 11.2 7.0 0.21 11.0 7.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 KXX80265.1 - 0.28 10.2 17.7 0.4 9.7 17.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 KXX80265.1 - 0.31 9.4 4.6 0.34 9.2 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MDM10 PF12519.8 KXX80265.1 - 0.39 9.5 12.3 0.52 9.1 12.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 EIF4E-T PF10477.9 KXX80265.1 - 0.39 9.5 26.3 0.022 13.6 21.0 1.5 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E YjbH PF06082.11 KXX80265.1 - 0.55 9.0 12.1 0.65 8.7 12.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH WDCP PF15390.6 KXX80265.1 - 0.6 8.4 10.1 0.72 8.2 10.1 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ABC2_membrane_2 PF12679.7 KXX80265.1 - 0.69 9.1 1.8 0.95 8.7 1.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Hid1 PF12722.7 KXX80265.1 - 0.84 7.7 21.8 1.1 7.3 21.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WTX PF09422.10 KXX80265.1 - 0.95 8.5 15.9 1.2 8.1 15.9 1.1 1 0 0 1 1 1 0 WTX protein OATP PF03137.20 KXX80265.1 - 1.2 7.3 5.4 1.5 7.0 5.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MID_MedPIWI PF18296.1 KXX80265.1 - 1.5 8.6 18.3 2.1 8.1 18.3 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Ndc1_Nup PF09531.10 KXX80265.1 - 1.6 7.4 13.2 1.8 7.2 13.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.6 KXX80265.1 - 2 7.1 18.1 2.9 6.5 18.1 1.2 1 0 0 1 1 1 0 Raftlin Paf1 PF03985.13 KXX80265.1 - 2.6 7.0 34.5 3.8 6.4 34.5 1.2 1 0 0 1 1 1 0 Paf1 MCM_bind PF09739.9 KXX80265.1 - 2.7 6.3 19.6 3.9 5.8 19.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Gti1_Pac2 PF09729.9 KXX80265.1 - 2.8 8.0 17.2 4.6 7.3 17.2 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Band_3_cyto PF07565.13 KXX80265.1 - 3 7.6 19.1 5.1 6.8 19.1 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TERB2 PF15101.6 KXX80265.1 - 3.1 7.8 29.2 1.5 8.8 26.7 1.7 2 0 0 2 2 1 0 Telomere-associated protein TERB2 FAM60A PF15396.6 KXX80265.1 - 3.4 7.6 18.0 6 6.8 18.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A UPF0560 PF10577.9 KXX80265.1 - 3.4 6.1 27.5 4.7 5.6 27.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Serinc PF03348.15 KXX80265.1 - 3.8 6.3 10.1 5 5.9 10.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 KXX80265.1 - 4 7.1 17.4 6.3 6.5 17.4 1.4 1 0 0 1 1 1 0 Connexin Baculo_PP31 PF05311.11 KXX80265.1 - 4.4 6.7 18.4 6.9 6.1 18.4 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Rrn6 PF10214.9 KXX80265.1 - 5.5 5.4 23.3 8 4.8 23.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4569 PF15133.6 KXX80265.1 - 5.8 6.5 20.8 9.8 5.8 20.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Pannexin_like PF12534.8 KXX80265.1 - 6.1 5.8 14.2 12 4.9 14.2 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 NPR3 PF03666.13 KXX80265.1 - 6.7 5.4 20.5 4.7 5.9 19.0 1.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 YABBY PF04690.13 KXX80265.1 - 6.9 7.2 14.9 7 7.2 13.3 1.9 2 0 0 2 2 1 0 YABBY protein Pal1 PF08316.11 KXX80265.1 - 9.3 7.0 10.7 20 6.0 10.7 1.5 1 0 0 1 1 1 0 Pal1 cell morphology protein PPL5 PF18168.1 KXX80265.1 - 10 5.3 15.9 15 4.7 15.9 1.4 1 0 0 1 1 1 0 Prim-pol family 5 PAP_assoc PF03828.19 KXX80266.1 - 1.5e-17 63.6 0.0 1.8e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXX80266.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain TPR_1 PF00515.28 KXX80266.1 - 0.095 12.6 0.2 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIF_alpha PF05793.12 KXX80267.1 - 0.22 10.1 55.5 9.9 4.6 55.2 2.9 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.9 KXX80268.1 - 1.8e-21 77.1 5.7 1.8e-21 77.1 5.7 2.9 1 1 2 3 3 3 1 Pre-mRNA-splicing factor of RES complex TFIIA PF03153.13 KXX80268.1 - 1.2 9.0 11.9 1.7 8.6 11.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXX80269.1 - 0.94 9.0 10.2 1.5 8.4 10.2 1.2 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 KXX80269.1 - 4.9 6.1 5.9 7.1 5.6 5.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein 2_5_RNA_ligase2 PF13563.6 KXX80270.1 - 1.7e-33 115.7 0.0 4.5e-33 114.3 0.0 1.8 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 KXX80270.1 - 1.3e-21 76.7 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 KXX80270.1 - 7.4e-20 71.5 0.6 1.8e-19 70.2 0.6 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 KXX80270.1 - 8.9e-08 31.9 0.0 3.6e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 KXX80270.1 - 0.00041 20.6 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PBP1_TM PF14812.6 KXX80270.1 - 0.39 11.1 2.4 1.3 9.5 2.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_61 PF03443.14 KXX80271.1 - 2.9e-61 207.0 0.0 3.6e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.21 KXX80272.1 - 1.2e-105 353.8 41.8 1.5e-105 353.6 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXX80272.1 - 1.1e-29 103.5 45.7 1.5e-29 103.1 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease NUDIX PF00293.28 KXX80273.1 - 1.6e-14 54.1 0.8 5.8e-14 52.3 0.3 1.9 2 0 0 2 2 2 1 NUDIX domain Pribosyltran_N PF13793.6 KXX80274.1 - 2.7e-43 146.6 0.0 5.1e-42 142.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXX80274.1 - 7e-34 117.5 0.1 1.4e-29 103.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXX80274.1 - 1.7e-08 34.2 0.0 0.00016 21.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain XPG_I_2 PF12813.7 KXX80275.1 - 8.1e-68 228.6 0.0 1.4e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing HEAT_2 PF13646.6 KXX80275.1 - 1.6e-26 92.5 4.7 6.4e-13 48.9 0.1 3.8 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 KXX80275.1 - 1.5e-17 62.4 13.7 0.0083 16.7 0.7 7.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KXX80275.1 - 4.7e-07 29.5 1.2 0.43 11.0 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KXX80275.1 - 0.028 14.9 11.2 0.11 13.0 0.1 5.5 4 1 2 6 6 6 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KXX80275.1 - 0.059 13.7 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PAN_1 PF00024.26 KXX80276.1 - 0.042 13.8 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 PAN domain CD52 PF15116.6 KXX80276.1 - 0.84 9.7 4.3 1.9 8.6 0.4 2.5 2 0 0 2 2 2 0 CAMPATH-1 antigen Phage_holin_3_5 PF16085.5 KXX80276.1 - 2.5 8.3 7.1 1.1 9.4 4.6 1.6 1 1 0 1 1 1 0 Bacteriophage holin Hol, superfamily III Homeobox_KN PF05920.11 KXX80277.1 - 2.7e-16 59.2 0.9 7.5e-16 57.8 0.9 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KXX80277.1 - 4.6e-15 55.4 6.8 1.9e-06 27.8 0.0 5.6 5 1 0 5 5 5 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KXX80277.1 - 1.8e-06 27.7 0.9 5.5e-06 26.1 0.9 1.9 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KXX80277.1 - 0.0033 18.1 3.8 0.0033 18.1 3.8 4.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX80277.1 - 0.0043 17.4 15.6 0.041 14.3 3.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type CpXC PF14353.6 KXX80277.1 - 0.11 12.5 0.2 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 CpXC protein zf-C2H2_jaz PF12171.8 KXX80277.1 - 0.42 10.9 1.8 2.1 8.7 1.8 2.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 KXX80277.1 - 1 9.4 5.1 12 6.1 5.2 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Nipped-B_C PF12830.7 KXX80278.1 - 3.4e-46 157.6 0.6 3.4e-46 157.6 0.6 3.8 4 1 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KXX80278.1 - 1.7e-08 34.6 2.9 4.5e-07 30.0 0.6 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KXX80278.1 - 2.7e-05 24.3 0.6 0.0012 19.0 0.0 2.8 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXX80278.1 - 0.00015 21.8 5.4 0.3 11.5 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat SKA2 PF16740.5 KXX80278.1 - 0.0029 17.4 0.0 0.013 15.3 0.0 2.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 NEMO PF11577.8 KXX80278.1 - 0.16 12.0 0.0 0.68 10.0 0.0 2.1 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO PRP38_assoc PF12871.7 KXX80279.1 - 0.58 10.8 24.6 0.68 10.6 8.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term YAcAr PF10686.9 KXX80281.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Ras PF00071.22 KXX80282.1 - 1e-39 135.8 0.0 1.7e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXX80282.1 - 6e-31 107.2 0.0 8.6e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX80282.1 - 2.3e-09 36.9 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXX80282.1 - 0.00069 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RTP1_C2 PF10304.9 KXX80282.1 - 0.023 14.4 0.3 0.04 13.6 0.3 1.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 AAA_33 PF13671.6 KXX80282.1 - 0.036 14.2 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KXX80282.1 - 0.038 13.4 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KXX80282.1 - 0.045 14.1 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 KXX80282.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 KXX80282.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 KXX80282.1 - 0.25 10.7 0.0 0.42 9.9 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FMN_dh PF01070.18 KXX80283.1 - 1e-117 393.1 1.0 1.2e-117 392.8 1.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXX80283.1 - 7.2e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXX80283.1 - 2.8e-07 30.0 0.1 4.4e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXX80283.1 - 8.9e-05 21.6 1.6 0.00061 18.9 0.1 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXX80283.1 - 0.0013 18.2 1.0 0.0017 17.8 0.2 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KXX80283.1 - 0.0054 16.2 0.7 0.2 11.1 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.12 KXX80283.1 - 0.084 12.0 0.0 1.8 7.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF561) ThiG PF05690.14 KXX80283.1 - 0.13 11.6 0.0 4.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Coatomer_E PF04733.14 KXX80285.1 - 0.0055 16.2 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Coatomer epsilon subunit ResIII PF04851.15 KXX80286.1 - 1e-19 71.2 0.0 3.3e-19 69.5 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXX80286.1 - 5.7e-14 52.4 0.0 1.5e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX80286.1 - 2.6e-10 40.4 0.1 8e-10 38.8 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KXX80286.1 - 0.097 11.9 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PI3_PI4_kinase PF00454.27 KXX80288.1 - 1.7e-44 152.5 0.0 2.4e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Acetyltransf_10 PF13673.7 KXX80289.1 - 6.2e-12 45.6 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX80289.1 - 1.1e-07 32.1 0.0 1.8e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX80289.1 - 4.6e-06 27.0 0.0 9.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX80289.1 - 9.3e-05 22.3 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXX80289.1 - 0.0036 17.4 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXX80289.1 - 0.029 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Zn_clus PF00172.18 KXX80290.1 - 0.013 15.6 12.2 0.024 14.7 12.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXX80291.1 - 2.9e-30 105.4 6.2 4.8e-30 104.7 6.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX80291.1 - 3.8e-10 39.2 3.9 8.4e-10 38.1 2.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KXX80291.1 - 4.9e-05 21.9 2.6 4.9e-05 21.9 2.6 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 KXX80291.1 - 7.4e-05 21.5 4.1 0.1 11.2 0.0 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 KXX80291.1 - 0.0084 14.6 1.1 0.013 13.9 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 KXX80291.1 - 0.047 12.5 2.0 0.047 12.5 0.4 1.7 2 0 0 2 2 2 0 LacY proton/sugar symporter DUF4131 PF13567.6 KXX80291.1 - 0.066 12.9 5.4 1.3 8.6 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF5518 PF17647.1 KXX80291.1 - 0.82 9.8 11.3 1.5 9.0 2.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5518) Formyl_trans_N PF00551.19 KXX80292.1 - 1.2e-37 129.4 0.1 1.5e-37 129.1 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KXX80292.1 - 3.3e-07 30.0 0.0 8.8e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KXX80292.1 - 0.00072 19.5 0.0 0.0019 18.1 0.0 1.8 1 0 0 1 1 1 1 ACT domain ZnuA PF01297.17 KXX80292.1 - 0.039 13.4 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic SSF PF00474.17 KXX80293.1 - 1e-17 64.1 30.0 1e-17 64.1 30.0 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family Glyco_hydro_3_C PF01915.22 KXX80294.1 - 5.9e-43 147.2 0.0 1.2e-42 146.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX80294.1 - 2.3e-42 145.5 0.0 3.3e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX80294.1 - 4.2e-26 90.8 0.1 8.9e-26 89.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CFEM PF05730.11 KXX80295.1 - 9.9e-12 44.8 7.3 1.3e-11 44.4 7.3 1.2 1 0 0 1 1 1 1 CFEM domain SH3_1 PF00018.28 KXX80297.1 - 2.4e-09 36.6 0.1 3.7e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXX80297.1 - 1.3e-06 27.9 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXX80297.1 - 2.1e-06 27.5 0.0 4.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1129 PF06570.11 KXX80297.1 - 0.74 9.3 2.7 1.2 8.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Dynactin_p22 PF07426.11 KXX80298.1 - 1.9e-08 34.4 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 FAD-SLDH PF12318.8 KXX80298.1 - 0.02 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Aa_trans PF01490.18 KXX80299.1 - 7.6e-88 295.0 10.5 1.1e-87 294.4 10.5 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXX80299.1 - 0.00053 19.1 13.5 0.001 18.2 13.5 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family YlaH PF14036.6 KXX80299.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.2 2 0 0 2 2 2 0 YlaH-like protein ABC2_membrane_2 PF12679.7 KXX80299.1 - 2 7.6 10.4 0.62 9.3 0.6 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein Ribosomal_S16 PF00886.19 KXX80300.1 - 6e-26 90.3 0.0 9.2e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 KXX80301.1 - 2.6e-32 112.1 0.0 3.2e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 KXX80301.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Glyco_hydro_16 PF00722.21 KXX80302.1 - 7.4e-38 129.8 0.2 1.4e-37 128.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.22 KXX80303.1 - 9.8e-51 172.9 0.0 2.3e-50 171.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KXX80304.1 - 2.6e-06 27.2 0.1 7.7e-06 25.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like PLA2_B PF01735.18 KXX80305.1 - 0.053 11.9 0.0 0.086 11.2 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain GSH-S_N PF02951.14 KXX80306.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Sec7_N PF12783.7 KXX80306.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CREPT PF16566.5 KXX80306.1 - 0.15 12.2 1.2 2.1 8.5 0.1 3.0 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour DUF983 PF06170.12 KXX80308.1 - 5.9 7.4 10.4 0.44 11.0 2.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) DUF2076 PF09849.9 KXX80309.1 - 0.12 12.4 1.4 0.12 12.4 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) EHN PF06441.12 KXX80310.1 - 5.7e-28 97.4 0.3 1.1e-27 96.5 0.3 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXX80310.1 - 5.4e-06 26.2 0.2 1.2e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Clr5 PF14420.6 KXX80311.1 - 8.7e-09 35.5 0.1 1.1e-08 35.2 0.1 1.1 1 0 0 1 1 1 1 Clr5 domain Sugar_tr PF00083.24 KXX80313.1 - 1.2e-77 261.7 19.8 1.5e-77 261.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX80313.1 - 7.4e-17 61.3 26.1 7.4e-17 61.3 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NIPSNAP PF07978.13 KXX80314.1 - 7.6e-41 138.5 0.7 1.3e-29 102.4 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP SR-25 PF10500.9 KXX80314.1 - 0.18 11.4 6.7 0.28 10.8 6.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FSH1 PF03959.13 KXX80315.1 - 4.5e-57 193.1 0.0 5.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXX80315.1 - 0.003 17.4 0.0 1.3 8.8 0.2 3.1 3 1 0 3 3 3 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXX80315.1 - 0.071 12.4 0.2 0.43 9.8 0.0 2.2 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Rpp20 PF12328.8 KXX80316.1 - 1.3e-26 93.2 1.0 1.6e-26 92.9 1.0 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KXX80316.1 - 1.3e-09 37.7 0.0 4.1e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Alba Rogdi_lz PF10259.9 KXX80317.1 - 2.9e-89 299.1 0.0 2.2e-47 161.8 0.9 2.0 1 1 1 2 2 2 2 Rogdi leucine zipper containing protein ABC2_membrane PF01061.24 KXX80318.1 - 1.1e-86 289.6 48.9 4e-44 150.6 14.8 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXX80318.1 - 1.5e-39 135.7 0.1 2.6e-19 70.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXX80318.1 - 2.7e-28 97.7 0.0 1.9e-23 82.2 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXX80318.1 - 3.6e-16 59.5 0.3 3.6e-16 59.5 0.3 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXX80318.1 - 4.8e-07 30.3 0.9 0.0012 19.3 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KXX80318.1 - 2.1e-05 24.7 0.1 0.17 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KXX80318.1 - 3.5e-05 23.8 0.0 0.077 12.8 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXX80318.1 - 4e-05 23.6 0.2 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KXX80318.1 - 5.6e-05 22.4 9.6 5.6e-05 22.4 9.6 2.6 3 0 0 3 3 2 1 ABC-2 family transporter protein AAA_18 PF13238.6 KXX80318.1 - 5.8e-05 23.6 0.0 0.0012 19.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXX80318.1 - 0.00028 21.2 0.0 0.22 11.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXX80318.1 - 0.00051 20.1 0.0 0.055 13.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KXX80318.1 - 0.00063 19.4 0.3 0.48 10.2 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KXX80318.1 - 0.0023 18.2 0.0 0.0066 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXX80318.1 - 0.0028 17.3 0.0 0.085 12.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KXX80318.1 - 0.017 15.1 0.1 1.4 8.8 0.3 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KXX80318.1 - 0.023 14.3 0.1 0.26 10.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXX80318.1 - 0.027 14.2 1.6 3.2 7.4 0.6 3.0 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 KXX80318.1 - 0.027 13.9 0.3 0.33 10.3 0.1 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 KXX80318.1 - 0.033 13.5 1.2 6.9 5.9 0.1 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXX80318.1 - 0.035 13.8 0.0 0.29 10.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 KXX80318.1 - 0.12 11.6 0.2 1.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 KXX80318.1 - 0.13 11.6 0.0 0.53 9.5 0.1 1.9 2 0 0 2 2 2 0 Septin AAA PF00004.29 KXX80318.1 - 0.13 12.7 0.0 28 5.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXX80318.1 - 0.15 11.2 0.2 2.9 7.0 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 KXX80318.1 - 0.18 10.9 0.0 9.1 5.3 0.0 2.9 2 1 0 2 2 2 0 G-protein alpha subunit AAA_19 PF13245.6 KXX80318.1 - 0.36 11.2 1.0 46 4.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain Cupin_2 PF07883.11 KXX80319.1 - 6.9e-08 32.1 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DNA_ligase_A_N PF04675.14 KXX80320.1 - 0.062 13.6 0.2 0.11 12.8 0.2 1.7 1 1 0 1 1 1 0 DNA ligase N terminus FAD_binding_3 PF01494.19 KXX80322.1 - 9.9e-11 41.5 0.2 3.3e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXX80322.1 - 6.5e-08 32.7 0.2 3.8e-07 30.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX80322.1 - 0.00011 21.5 1.2 0.00011 21.5 1.2 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXX80322.1 - 0.00027 20.7 1.8 0.00089 18.9 0.3 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX80322.1 - 0.00037 19.8 0.0 0.00067 19.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXX80322.1 - 0.0005 19.4 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXX80322.1 - 0.0014 17.8 0.9 0.002 17.3 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXX80322.1 - 0.0026 18.3 0.8 0.045 14.3 0.4 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX80322.1 - 0.0034 16.2 0.0 0.0073 15.1 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXX80322.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXX80322.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXX80322.1 - 0.13 11.6 1.1 0.21 10.9 1.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXX80322.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KXX80322.1 - 0.17 11.1 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Chitin_bind_1 PF00187.19 KXX80323.1 - 1.4e-16 60.7 64.0 1.1e-07 32.1 14.8 4.2 3 2 0 3 3 3 3 Chitin recognition protein Conotoxin PF02950.17 KXX80323.1 - 4 8.5 18.9 1.9 9.5 0.9 3.7 3 0 0 3 3 3 0 Conotoxin MIP PF00230.20 KXX80324.1 - 4.5e-48 163.9 16.0 5.9e-48 163.6 16.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Cofilin_ADF PF00241.20 KXX80325.1 - 1.4e-25 89.4 0.0 1.6e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3656 PF12392.8 KXX80325.1 - 0.0069 17.0 0.0 0.0096 16.6 0.0 1.2 1 0 0 1 1 1 1 Collagenase DASH_Spc19 PF08287.11 KXX80326.1 - 4.8e-50 169.5 0.0 6.7e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Spc19 Lzipper-MIP1 PF14389.6 KXX80326.1 - 0.035 14.4 1.2 2.8 8.3 3.9 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 bZIP_2 PF07716.15 KXX80327.1 - 2.3e-08 34.0 12.5 2.3e-08 34.0 12.5 1.6 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KXX80327.1 - 2.3e-08 34.0 9.7 3.4e-08 33.5 9.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXX80327.1 - 0.00026 21.4 6.4 0.00039 20.9 6.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Takusan PF04822.13 KXX80327.1 - 0.009 15.9 2.5 0.016 15.1 2.5 1.4 1 0 0 1 1 1 1 Takusan IMUP PF15761.5 KXX80327.1 - 0.053 14.2 2.2 0.079 13.7 2.2 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein TPD52 PF04201.15 KXX80327.1 - 0.076 12.6 1.8 0.12 12.0 1.8 1.4 1 0 0 1 1 1 0 Tumour protein D52 family ZapB PF06005.12 KXX80327.1 - 0.1 13.0 5.4 0.16 12.4 5.4 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Pyocin_S PF06958.12 KXX80327.1 - 0.14 12.7 2.8 0.18 12.3 2.3 1.5 1 1 0 1 1 1 0 S-type Pyocin DUF4140 PF13600.6 KXX80327.1 - 0.15 12.5 2.8 0.25 11.8 2.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) WD40_alt PF14077.6 KXX80327.1 - 0.22 11.4 3.2 5.5 6.9 0.3 2.2 1 1 1 2 2 2 0 Alternative WD40 repeat motif PKcGMP_CC PF16808.5 KXX80327.1 - 0.77 9.7 10.8 2.6 8.0 3.8 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 KXX80327.1 - 1.6 7.7 6.8 2 7.4 6.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HNH_2 PF13391.6 KXX80332.1 - 2.4e-12 46.8 0.5 6e-12 45.5 0.5 1.7 1 0 0 1 1 1 1 HNH endonuclease BTB PF00651.31 KXX80335.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HET PF06985.11 KXX80337.1 - 1.7e-11 44.7 5.3 9.1e-10 39.1 0.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GIIM PF08388.11 KXX80337.1 - 0.19 11.8 0.0 0.5 10.5 0.0 1.6 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Raf1_HTH PF18579.1 KXX80337.1 - 0.31 10.7 1.4 0.32 10.7 0.1 1.7 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Na_H_Exchanger PF00999.21 KXX80338.1 - 7.2e-48 163.3 23.3 9.2e-48 162.9 23.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family p450 PF00067.22 KXX80339.1 - 4.8e-40 137.7 0.0 1.4e-32 113.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Ank_4 PF13637.6 KXX80339.1 - 2.6e-17 63.0 0.0 7e-09 36.1 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX80339.1 - 4.1e-16 59.3 0.0 3.4e-15 56.4 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX80339.1 - 6.4e-14 50.7 0.0 0.0017 18.7 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KXX80339.1 - 1.2e-12 47.6 0.0 0.00046 20.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXX80339.1 - 3.6e-12 46.3 0.0 1.6e-06 28.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) FAR1 PF03101.15 KXX80339.1 - 1.8e-05 25.3 0.1 3.6e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF3237 PF11578.8 KXX80340.1 - 1.7e-24 86.3 1.6 4.3e-18 65.6 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) End_beta_barrel PF12195.8 KXX80340.1 - 0.089 12.8 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase Pkinase PF00069.25 KXX80341.1 - 2.3e-28 99.3 0.0 9.3e-28 97.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80341.1 - 3.3e-06 26.6 0.2 5.3e-05 22.6 0.2 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX80341.1 - 0.0023 16.8 0.0 0.0083 14.9 0.0 1.5 1 1 1 2 2 2 1 Fungal protein kinase Methyltransf_2 PF00891.18 KXX80342.1 - 2.2e-23 82.6 0.0 3.4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MFS_1 PF07690.16 KXX80343.1 - 1.2e-35 123.1 51.7 3.6e-34 118.2 51.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX80343.1 - 1.8e-05 23.8 26.2 3.1e-05 23.0 12.4 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 KXX80345.1 - 5.1e-30 104.7 0.0 4.2e-29 101.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80345.1 - 3.9e-05 23.1 0.2 0.0031 16.9 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXX80345.1 - 0.03 14.2 0.2 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXX80345.1 - 0.081 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Glyco_transf_25 PF01755.17 KXX80346.1 - 8.5e-08 32.3 0.0 2.5e-06 27.5 0.0 2.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_hydro_11 PF00457.17 KXX80347.1 - 1.7e-48 164.6 6.5 2.1e-48 164.3 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Tyrosinase PF00264.20 KXX80348.1 - 4.5e-32 112.1 0.2 4.8e-31 108.8 0.2 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase COesterase PF00135.28 KXX80349.1 - 3.6e-71 240.6 0.0 9.3e-62 209.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX80349.1 - 1.7e-07 31.3 0.2 4e-07 30.1 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX80349.1 - 0.00033 21.3 1.7 0.00033 21.3 1.7 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KXX80349.1 - 0.0034 16.9 0.2 0.0057 16.2 0.2 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXX80349.1 - 0.0075 15.8 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family CDH-cyt PF16010.5 KXX80350.1 - 1.8e-65 220.0 2.8 3.3e-65 219.2 1.8 1.9 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_C PF05199.13 KXX80350.1 - 1.6e-23 83.8 0.1 3.2e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXX80350.1 - 2.2e-22 79.8 0.0 5.6e-22 78.5 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX80350.1 - 6.9e-08 32.0 0.0 0.00039 19.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXX80350.1 - 0.00015 21.9 0.0 0.00041 20.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX80350.1 - 0.00081 18.7 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX80350.1 - 0.00097 18.8 1.0 0.0067 16.0 1.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX80350.1 - 0.0023 16.7 0.0 0.0035 16.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DOMON PF03351.17 KXX80350.1 - 0.0053 17.0 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 DOMON domain Pyr_redox_3 PF13738.6 KXX80350.1 - 0.017 14.4 0.2 0.029 13.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX80350.1 - 0.018 14.1 0.1 0.041 12.9 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KXX80350.1 - 0.086 13.4 0.0 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX80350.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXX80350.1 - 0.1 11.9 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pkinase PF00069.25 KXX80351.1 - 2.5e-19 69.7 0.0 4.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80351.1 - 2.3e-09 36.9 0.0 1.1e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXX80351.1 - 0.014 15.4 0.3 0.48 10.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Glyco_hydro_61 PF03443.14 KXX80352.1 - 6.7e-48 163.4 0.1 8e-48 163.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ferritin_2 PF13668.6 KXX80353.1 - 8.6e-17 61.6 0.0 1.9e-16 60.5 0.0 1.5 2 0 0 2 2 2 1 Ferritin-like domain Beta_helix PF13229.6 KXX80354.1 - 0.00013 21.9 29.3 0.002 18.0 21.6 2.4 1 1 1 2 2 2 2 Right handed beta helix region NTP_transf_9 PF04248.12 KXX80359.1 - 4.6e-32 109.8 0.2 3.9e-31 106.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF427) HET PF06985.11 KXX80360.1 - 1.4e-07 32.0 0.8 0.00025 21.4 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NAD_binding_10 PF13460.6 KXX80361.1 - 8.4e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXX80361.1 - 0.034 13.3 0.0 8.9 5.4 0.0 2.7 2 1 1 3 3 3 0 Male sterility protein DJ-1_PfpI PF01965.24 KXX80362.1 - 1.1e-14 54.5 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family NAD_binding_8 PF13450.6 KXX80363.1 - 0.0075 16.5 2.1 0.0075 16.5 2.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX80363.1 - 0.012 14.9 7.7 0.23 10.6 7.7 2.2 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KXX80363.1 - 0.043 13.0 1.1 0.17 11.1 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX80363.1 - 2.2 8.3 4.4 3.2 7.7 1.2 2.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXX80364.1 - 3e-09 36.6 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KXX80364.1 - 0.0035 16.4 0.0 0.0068 15.5 0.0 1.4 2 0 0 2 2 2 1 Squalene epoxidase DUF5587 PF17825.1 KXX80364.1 - 0.22 8.8 0.1 0.31 8.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5587) DUF3237 PF11578.8 KXX80366.1 - 2e-18 66.7 0.0 6.7e-13 48.7 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) NACHT PF05729.12 KXX80367.1 - 8.8e-05 22.5 0.0 0.00027 20.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXX80367.1 - 0.00016 22.0 0.0 0.0015 18.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXX80367.1 - 0.00037 20.9 0.0 0.0058 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KXX80367.1 - 0.0047 17.5 0.1 0.014 16.0 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXX80367.1 - 0.0094 15.5 0.0 0.054 13.0 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) KAP_NTPase PF07693.14 KXX80367.1 - 0.017 14.4 0.2 3.3 6.9 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 KXX80367.1 - 0.026 14.2 0.0 0.079 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXX80367.1 - 0.037 14.4 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Hydrolase_4 PF12146.8 KXX80367.1 - 0.075 12.3 0.0 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AAA_18 PF13238.6 KXX80367.1 - 0.098 13.2 0.0 0.4 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXX80367.1 - 0.16 12.4 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PGAP1 PF07819.13 KXX80367.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein p450 PF00067.22 KXX80368.1 - 5.2e-58 196.9 0.0 7.1e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.16 KXX80370.1 - 1.8e-32 113.2 0.1 2.6e-32 112.7 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_M66 PF10462.9 KXX80370.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 MFS_1 PF07690.16 KXX80371.1 - 1.4e-27 96.5 4.4 1.4e-27 96.5 4.4 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXX80371.1 - 0.0054 15.3 1.0 0.0054 15.3 1.0 3.8 3 1 0 3 3 3 1 MFS/sugar transport protein DUF5367 PF17329.2 KXX80371.1 - 0.019 15.1 5.9 1.4 9.1 2.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5367) TPR_12 PF13424.6 KXX80372.1 - 9.2e-40 134.8 20.3 2.2e-12 47.1 0.1 6.5 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KXX80372.1 - 1.5e-22 78.7 20.5 0.00012 21.8 0.1 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX80372.1 - 2e-13 50.4 17.0 4.8e-10 39.3 8.9 3.5 1 1 2 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 KXX80372.1 - 9.1e-08 31.7 8.3 0.21 11.9 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX80372.1 - 2e-07 31.4 17.6 0.69 10.5 1.2 6.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 KXX80372.1 - 1e-06 28.8 29.9 0.046 14.4 0.3 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX80372.1 - 4.8e-05 23.2 25.5 0.91 9.8 0.4 8.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX80372.1 - 0.00083 20.0 13.9 0.31 11.7 0.0 6.5 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXX80372.1 - 0.001 19.5 14.8 1.9 9.3 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat NACHT PF05729.12 KXX80372.1 - 0.0016 18.4 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX80372.1 - 0.0025 18.2 0.0 0.015 15.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXX80372.1 - 0.0039 17.5 0.1 0.026 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain TPR_7 PF13176.6 KXX80372.1 - 0.011 15.7 13.0 0.3 11.2 0.1 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX80372.1 - 0.014 16.1 29.1 8 7.6 0.3 9.2 8 2 2 10 10 8 0 Tetratricopeptide repeat NB-ARC PF00931.22 KXX80372.1 - 0.039 13.1 0.0 0.27 10.4 0.0 2.3 1 1 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KXX80372.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_1 PF00515.28 KXX80372.1 - 1.8 8.5 18.4 5.7 6.9 0.1 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Hva1_TUDOR PF11160.8 KXX80373.1 - 1.4e-13 50.8 1.8 1.7e-13 50.5 1.8 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain HNH PF01844.23 KXX80373.1 - 0.4 10.9 2.8 2.8 8.2 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease Amidase PF01425.21 KXX80374.1 - 2.1e-72 244.5 0.0 2.7e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.25 KXX80375.1 - 6.8e-08 32.2 0.0 1.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80375.1 - 2.7e-05 23.6 0.0 0.00017 21.0 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Zn_clus PF00172.18 KXX80376.1 - 0.32 11.1 7.4 1 9.5 7.4 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4246 PF14033.6 KXX80377.1 - 3.4e-162 540.6 0.0 4e-162 540.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KXX80377.1 - 0.084 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.24 KXX80378.1 - 6.6e-114 381.2 27.8 7.6e-114 381.0 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX80378.1 - 1.3e-22 80.3 54.4 3.2e-18 65.8 28.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Meth_synt_2 PF01717.18 KXX80379.1 - 6.7e-15 55.2 0.0 1.2e-14 54.4 0.0 1.4 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXX80379.1 - 0.022 14.3 0.0 0.12 11.9 0.0 2.1 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain Gelsolin PF00626.22 KXX80380.1 - 1.8e-25 88.6 0.0 3.4e-07 30.1 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Abhydrolase_6 PF12697.7 KXX80381.1 - 3.3e-20 73.6 0.0 3.8e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX80381.1 - 0.00015 21.5 0.0 0.008 15.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX80381.1 - 0.0027 17.0 0.1 0.094 12.0 0.2 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KXX80381.1 - 0.0068 16.2 0.1 0.034 13.9 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KXX80381.1 - 0.019 14.5 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Zeta_toxin PF06414.12 KXX80381.1 - 0.045 13.0 0.0 0.28 10.4 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin Abhydrolase_2 PF02230.16 KXX80381.1 - 0.088 12.6 0.2 0.34 10.7 0.0 2.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KXX80381.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KXX80382.1 - 1.9e-22 80.2 0.1 9.6e-19 68.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXX80382.1 - 7.7e-20 70.9 0.0 1.9e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Peptidase_S41 PF03572.18 KXX80383.1 - 1.2e-06 28.2 0.0 3.4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 BNR_2 PF13088.6 KXX80384.1 - 0.0022 17.3 0.4 0.0096 15.3 0.4 2.0 1 1 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KXX80384.1 - 0.12 11.1 0.6 2.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 KXX80384.1 - 0.38 10.9 7.6 6.6 7.2 0.3 3.5 3 0 0 3 3 3 0 BNR/Asp-box repeat TILa PF12714.7 KXX80385.1 - 0.18 11.8 0.2 0.18 11.8 0.2 3.8 2 1 2 4 4 4 0 TILa domain Adaptin_N PF01602.20 KXX80386.1 - 2e-139 465.5 4.4 2.9e-139 465.0 4.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXX80386.1 - 4.4e-64 215.4 2.5 9e-62 207.9 0.1 2.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXX80386.1 - 1.7e-17 63.6 0.0 2.1e-07 31.2 0.0 5.5 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 KXX80386.1 - 3e-11 42.6 6.2 0.0074 16.5 0.0 6.9 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 KXX80386.1 - 6e-05 23.5 0.9 0.58 10.7 0.0 5.1 4 1 1 5 5 5 1 HEAT-like repeat Arm PF00514.23 KXX80386.1 - 0.0019 18.2 0.6 11 6.3 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KXX80386.1 - 0.019 14.9 1.0 0.25 11.3 0.0 2.8 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 KXX80386.1 - 0.025 14.7 0.8 1.5 9.1 0.0 3.9 1 1 2 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 KXX80386.1 - 0.043 13.8 0.0 3.9 7.6 0.0 3.2 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 KXX80386.1 - 0.058 12.9 0.2 2.4 7.6 0.0 3.1 3 1 1 4 4 4 0 CLASP N terminal CAAP1 PF15335.6 KXX80386.1 - 0.5 10.9 0.1 0.5 10.9 0.1 2.5 3 0 0 3 3 2 0 Caspase activity and apoptosis inhibitor 1 Ribosomal_60s PF00428.19 KXX80387.1 - 0.014 15.9 7.2 0.014 15.9 7.2 4.3 5 0 0 5 5 5 0 60s Acidic ribosomal protein PBP1_TM PF14812.6 KXX80387.1 - 0.03 14.7 3.8 0.03 14.7 3.8 4.1 4 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SOTI PF17079.5 KXX80387.1 - 2.9 8.3 5.9 37 4.8 0.2 3.3 3 0 0 3 3 3 0 Male-specific protein scotti Lipocalin_5 PF13924.6 KXX80388.1 - 7.9e-19 67.9 0.0 9.1e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain LVIVD PF08309.11 KXX80389.1 - 2e-07 30.2 3.1 0.28 10.5 0.0 4.3 4 0 0 4 4 4 4 LVIVD repeat NmrA PF05368.13 KXX80390.1 - 5.4e-11 42.5 0.0 2.6e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX80390.1 - 8.6e-07 29.0 0.2 4.4e-06 26.7 0.0 2.1 2 1 1 3 3 3 1 NAD(P)H-binding AflR PF08493.10 KXX80391.1 - 2.7e-08 33.6 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Asparaginase_2 PF01112.18 KXX80392.1 - 5.8e-70 235.7 3.0 7.3e-70 235.4 3.0 1.0 1 0 0 1 1 1 1 Asparaginase DUF2083 PF09856.9 KXX80392.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Cerato-platanin PF07249.12 KXX80393.1 - 2.3e-06 27.7 0.2 5.3e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 Cerato-platanin p450 PF00067.22 KXX80394.1 - 2.7e-76 257.2 0.0 3.3e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_20 PF00982.21 KXX80395.1 - 2e-199 663.2 0.0 2.3e-199 663.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KXX80395.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain CARDB PF07705.11 KXX80397.1 - 0.012 15.9 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 CARDB Arylsulfotran_2 PF14269.6 KXX80398.1 - 2e-19 70.1 0.1 2.7e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXX80398.1 - 0.00056 18.9 0.0 0.00076 18.5 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) p450 PF00067.22 KXX80400.1 - 6.2e-28 97.7 0.0 3.2e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 NHL PF01436.21 KXX80401.1 - 3.6e-05 23.6 0.0 1.2 9.3 0.0 4.2 3 1 1 4 4 4 2 NHL repeat SBBP PF06739.11 KXX80401.1 - 9.4e-05 22.3 0.2 0.47 10.5 0.0 3.3 3 0 0 3 3 3 2 Beta-propeller repeat SGL PF08450.12 KXX80401.1 - 0.0002 21.1 0.0 0.12 12.0 0.0 3.1 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KXX80401.1 - 0.01 15.1 0.2 1.9 7.6 0.2 2.3 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller GSDH PF07995.11 KXX80401.1 - 0.021 14.2 3.1 0.58 9.4 0.1 3.2 4 0 0 4 4 4 0 Glucose / Sorbosone dehydrogenase RCC1_2 PF13540.6 KXX80401.1 - 0.059 13.2 2.0 5.7 6.9 0.1 3.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Hexapep PF00132.24 KXX80402.1 - 1.4e-13 50.0 12.8 4.9e-11 41.9 5.2 3.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXX80402.1 - 3.1e-13 49.2 8.0 3.3e-10 39.5 5.0 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KXX80402.1 - 3.7e-10 39.9 0.0 6.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Tyrosinase PF00264.20 KXX80403.1 - 1e-38 133.9 0.3 1.4e-38 133.5 0.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_88 PF07470.13 KXX80404.1 - 4.6e-86 289.0 0.1 5.2e-86 288.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 KXX80405.1 - 6.9e-30 104.2 30.0 6.9e-30 104.2 30.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXX80405.1 - 0.14 12.0 4.6 0.35 10.6 0.0 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ank_2 PF12796.7 KXX80406.1 - 4.1e-08 33.7 0.2 0.0011 19.6 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX80406.1 - 0.0018 18.5 0.4 0.19 12.1 0.1 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX80406.1 - 0.004 17.5 0.1 0.34 11.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KXX80406.1 - 0.014 15.8 5.0 0.069 13.6 0.2 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 KXX80406.1 - 0.066 13.8 0.1 0.34 11.5 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) ADP_ribosyl_GH PF03747.14 KXX80407.1 - 6.3e-59 200.1 0.5 9e-59 199.6 0.5 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase TetR_C_16 PF17920.1 KXX80407.1 - 0.048 13.9 0.5 0.72 10.1 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Rick_17kDa_Anti PF05433.15 KXX80407.1 - 2.4 8.1 6.8 11 6.0 0.5 2.7 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KXX80407.1 - 2.5 8.1 9.5 4.1 7.5 1.1 3.2 3 0 0 3 3 3 0 Glycine zipper Sugar_tr PF00083.24 KXX80408.1 - 2.6e-97 326.5 20.4 3e-97 326.3 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX80408.1 - 2e-34 119.1 46.5 1.2e-29 103.4 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX80408.1 - 0.0011 17.5 10.1 0.0041 15.6 3.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) ATP-synt_C PF00137.21 KXX80409.1 - 1.9e-13 50.5 15.9 1.1e-12 48.1 11.4 2.4 2 1 0 2 2 2 2 ATP synthase subunit C MFS_3 PF05977.13 KXX80409.1 - 0.037 12.4 8.6 0.04 12.3 8.6 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Beta_helix_2 PF18835.1 KXX80409.1 - 0.053 13.3 0.2 0.094 12.5 0.2 1.4 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase p450 PF00067.22 KXX80410.1 - 2.3e-37 128.9 0.0 3.1e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 KXX80410.1 - 0.29 10.8 1.4 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 KXX80411.1 - 3.3e-32 111.8 24.0 4.4e-32 111.4 24.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3341 PF11821.8 KXX80411.1 - 4.5 6.9 8.6 0.31 10.7 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) Glyco_hydro_61 PF03443.14 KXX80412.1 - 7.8e-34 117.4 0.0 9.3e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SHIPPO-rpt PF07004.12 KXX80412.1 - 0.13 13.2 2.1 0.65 11.0 2.1 2.3 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat Alpha_kinase PF02816.18 KXX80413.1 - 5.6e-50 170.0 0.0 6.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family CHD5 PF04420.14 KXX80415.1 - 0.13 12.1 0.9 0.31 10.9 0.9 1.6 1 0 0 1 1 1 0 CHD5-like protein Snf7 PF03357.21 KXX80416.1 - 2.1e-07 30.7 1.8 3.4e-07 30.0 0.2 1.8 1 1 1 2 2 2 1 Snf7 Aminotran_3 PF00202.21 KXX80417.1 - 3.2e-25 88.6 0.0 1.4e-23 83.3 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.21 KXX80418.1 - 3.5e-13 49.0 0.0 3.5e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF1045 PF06299.12 KXX80419.1 - 0.093 12.7 0.4 0.18 11.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) NAD_binding_10 PF13460.6 KXX80420.1 - 1.2e-09 38.4 0.0 3.1e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX80420.1 - 9.4e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Stanniocalcin PF03298.13 KXX80421.1 - 5.2e-05 22.7 3.8 9.3e-05 21.8 3.8 1.3 1 0 0 1 1 1 1 Stanniocalcin family CarboxypepD_reg PF13620.6 KXX80421.1 - 0.0001 22.5 2.2 0.00012 22.3 0.1 2.3 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 KXX80421.1 - 0.075 13.1 0.0 0.075 13.1 0.0 3.8 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 1) Sugar_tr PF00083.24 KXX80422.1 - 9.7e-108 360.9 23.2 1.2e-107 360.6 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX80422.1 - 2.5e-25 89.2 32.6 1.8e-17 63.3 8.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 KXX80423.1 - 7.5e-28 97.8 2.0 8.8e-28 97.5 2.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_hydro_61 PF03443.14 KXX80424.1 - 1.3e-29 103.6 0.0 1.6e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Trp_DMAT PF11991.8 KXX80425.1 - 8.9e-83 278.7 0.0 1.1e-82 278.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase SnoaL_2 PF12680.7 KXX80426.1 - 0.096 13.3 0.0 0.31 11.7 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain AMP-binding PF00501.28 KXX80427.1 - 6.5e-275 911.2 0.4 4e-75 253.0 0.0 4.4 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KXX80427.1 - 2.9e-178 593.2 0.0 1.7e-45 155.5 0.0 7.4 6 2 0 6 6 6 5 Condensation domain PP-binding PF00550.25 KXX80427.1 - 8.1e-33 112.6 0.4 3.3e-11 43.4 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXX80427.1 - 0.027 15.4 0.2 25 5.9 0.0 3.9 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KXX80428.1 - 3e-37 128.4 0.0 4e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KXX80428.1 - 6.7e-13 48.8 0.7 1.9e-10 41.0 0.1 2.9 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding PF00501.28 KXX80428.1 - 0.00037 19.2 0.1 0.00055 18.6 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_2_C PF02836.17 KXX80429.1 - 3.7e-109 364.5 0.0 5e-109 364.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXX80429.1 - 1.2e-64 218.2 0.0 2.4e-64 217.3 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXX80429.1 - 5e-51 173.0 1.2 1.7e-50 171.3 0.4 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KXX80429.1 - 6.1e-15 55.9 0.0 1.2e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 KXX80429.1 - 1.4e-12 47.9 0.3 4.6e-12 46.3 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_42 PF02449.15 KXX80429.1 - 0.0027 17.1 0.2 0.0052 16.2 0.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase HET PF06985.11 KXX80430.1 - 1.6e-27 96.7 0.0 2.6e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SMP_LBD PF17047.5 KXX80431.1 - 2.9e-23 82.2 0.2 4e-23 81.8 0.2 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KXX80431.1 - 1.2e-20 73.7 0.0 8.2e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain Glycos_transf_N PF04413.16 KXX80431.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) WD40 PF00400.32 KXX80432.1 - 1.8e-07 31.7 5.7 0.36 11.8 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat RRM_1 PF00076.22 KXX80433.1 - 1.7e-67 223.2 2.6 3.7e-17 61.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXX80433.1 - 4.3e-12 45.7 0.0 0.00059 19.6 0.0 5.4 5 0 0 5 5 5 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXX80433.1 - 1.7e-07 31.1 0.0 0.082 12.9 0.0 4.9 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KXX80433.1 - 0.00061 19.9 0.0 16 5.7 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 KXX80433.1 - 0.0036 17.3 0.3 8.3 6.6 0.0 4.4 4 1 0 4 4 4 1 Limkain b1 Smg4_UPF3 PF03467.15 KXX80433.1 - 0.0084 16.1 0.5 0.41 10.7 0.2 3.1 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_3 PF08777.11 KXX80433.1 - 0.0095 16.0 0.2 3 7.9 0.0 4.2 5 0 0 5 5 5 1 RNA binding motif Nup35_RRM PF05172.13 KXX80433.1 - 0.069 13.1 0.0 1.3 9.0 0.0 3.0 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KXX80433.1 - 0.089 12.6 0.1 2.3 8.0 0.0 3.3 5 0 0 5 5 5 0 Rrp7 RRM-like N-terminal domain NOP5NT PF08156.13 KXX80433.1 - 0.13 12.7 0.3 0.95 9.9 0.3 2.6 1 0 0 1 1 1 0 NOP5NT (NUC127) domain Dus PF01207.17 KXX80434.1 - 2.1e-38 132.2 0.0 4.3e-29 101.6 0.0 2.5 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 KXX80434.1 - 0.21 11.6 4.5 4.7 7.2 0.3 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXX80434.1 - 9.3 6.5 11.1 3.3 7.9 1.8 2.6 2 0 0 2 2 2 0 Zinc finger domain Pro_isomerase PF00160.21 KXX80435.1 - 1.3e-49 168.6 0.2 1.4e-49 168.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 KXX80435.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Dynein_light PF01221.18 KXX80436.1 - 2.9e-38 130.1 1.5 3.3e-38 129.9 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 ELL PF10390.9 KXX80437.1 - 1.2e-06 28.3 0.1 1.2e-06 28.3 0.1 2.7 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL Peroxin-13_N PF04088.13 KXX80439.1 - 1e-50 171.8 0.0 1.4e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KXX80439.1 - 6.2e-08 32.2 0.0 6.2e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXX80439.1 - 6.9e-06 25.6 0.1 1.8e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX80439.1 - 0.00011 21.9 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.32 KXX80440.1 - 5.1e-08 33.5 12.2 0.2 12.6 0.0 7.8 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX80440.1 - 1.6e-05 25.1 0.9 1.4 9.3 0.0 5.8 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX80440.1 - 2.5e-05 23.4 0.0 0.023 13.7 0.0 3.7 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KXX80440.1 - 3.2e-05 23.6 0.1 0.00019 21.1 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KXX80440.1 - 0.0021 17.9 0.6 0.051 13.5 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat PD40 PF07676.12 KXX80440.1 - 0.011 15.7 0.1 6.9 6.7 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KXX80440.1 - 0.02 15.4 1.7 10 6.8 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain Frtz PF11768.8 KXX80440.1 - 0.18 10.1 0.0 0.76 8.0 0.0 1.9 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz NAPRTase PF04095.16 KXX80441.1 - 8.1e-55 186.0 0.2 3.8e-30 105.3 0.6 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KXX80441.1 - 3.6e-35 121.1 0.0 7.4e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Transglut_core PF01841.19 KXX80442.1 - 2.7e-15 56.8 1.1 6.3e-15 55.6 1.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KXX80442.1 - 7.7e-14 51.6 3.9 1.4e-13 50.7 3.9 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain NUDE_C PF04880.13 KXX80442.1 - 0.029 14.9 2.8 0.056 13.9 2.8 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ogr_Delta PF04606.12 KXX80442.1 - 0.16 12.0 1.7 0.63 10.1 1.7 2.0 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger ATP-synt_G PF04718.15 KXX80443.1 - 3.7e-33 114.3 1.9 5.9e-33 113.7 0.5 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Alpha_adaptin_C PF02296.16 KXX80443.1 - 0.089 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain ADH_N PF08240.12 KXX80444.1 - 2.3e-26 91.8 2.9 4.5e-26 90.9 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX80444.1 - 5e-17 62.1 0.0 7.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXX80444.1 - 1.7e-05 24.4 0.4 0.00032 20.2 0.4 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXX80444.1 - 0.085 13.9 0.0 0.15 13.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ceramidase PF05875.12 KXX80445.1 - 2.1e-31 109.3 12.7 2e-15 56.9 2.4 3.0 1 1 1 2 2 2 2 Ceramidase MerC PF03203.14 KXX80445.1 - 0.79 10.2 6.4 26 5.3 6.4 2.2 1 1 0 1 1 1 0 MerC mercury resistance protein Methyltransf_23 PF13489.6 KXX80446.1 - 1.9e-14 53.8 0.0 2.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX80446.1 - 1.2e-10 42.0 0.0 3.5e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX80446.1 - 4.2e-09 36.4 0.0 1.8e-07 31.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX80446.1 - 1.3e-07 32.2 0.0 3.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX80446.1 - 3.4e-06 26.7 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXX80446.1 - 5.1e-06 27.2 0.0 1.9e-05 25.3 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 KXX80446.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXX80446.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KXX80446.1 - 0.002 17.7 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KXX80446.1 - 0.013 14.8 0.0 0.088 12.1 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KXX80446.1 - 0.15 11.4 0.0 0.39 10.0 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family HIG_1_N PF04588.13 KXX80447.1 - 1.2e-05 25.5 3.8 1.2e-05 25.5 3.8 2.5 3 0 0 3 3 3 1 Hypoxia induced protein conserved region UreF PF01730.16 KXX80447.1 - 0.0018 18.9 1.4 0.0029 18.2 1.4 1.4 1 0 0 1 1 1 1 UreF Romo1 PF10247.9 KXX80447.1 - 0.095 13.1 4.3 0.22 11.9 4.3 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DMT_6 PF04342.12 KXX80447.1 - 0.14 12.3 0.1 0.22 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative member of DMT superfamily (DUF486) Kelch_1 PF01344.25 KXX80448.1 - 2.1e-40 136.1 18.7 3.1e-09 36.2 1.6 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KXX80448.1 - 2.8e-40 135.7 15.0 1.6e-07 31.1 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KXX80448.1 - 8.8e-36 121.5 19.1 2.4e-07 30.9 0.0 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KXX80448.1 - 4.2e-35 118.9 16.7 6.7e-07 29.4 0.0 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KXX80448.1 - 4.7e-35 119.4 16.9 2.3e-06 27.5 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KXX80448.1 - 2.3e-31 106.6 17.2 1.2e-08 34.6 0.4 6.5 6 0 0 6 6 6 6 Kelch motif API5 PF05918.11 KXX80448.1 - 0.14 10.9 0.6 0.2 10.5 0.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TEA PF01285.18 KXX80450.1 - 2.3e-21 75.6 0.0 6.3e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 TEA/ATTS domain HSP70 PF00012.20 KXX80451.1 - 1.1e-247 823.1 4.7 1.2e-247 822.9 4.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXX80451.1 - 8.8e-21 74.1 1.0 7.2e-20 71.0 0.3 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KXX80451.1 - 0.00035 19.7 0.2 0.012 14.6 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 KXX80451.1 - 0.024 15.0 5.7 0.81 10.1 0.1 3.5 3 2 0 3 3 3 0 Cell division protein FtsA DUF5300 PF17224.3 KXX80451.1 - 0.035 14.4 0.9 3.5 7.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5300) StbA PF06406.11 KXX80451.1 - 0.096 11.9 0.3 0.47 9.6 0.0 2.1 2 1 1 3 3 3 0 StbA protein zf-C2H2_aberr PF17017.5 KXX80452.1 - 1.4e-05 25.3 0.8 0.022 14.9 0.1 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KXX80452.1 - 0.00064 20.0 6.5 0.016 15.6 0.9 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXX80452.1 - 0.00076 19.8 13.2 0.11 13.0 1.6 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX80452.1 - 0.0016 19.1 18.2 0.024 15.4 1.1 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HE PF16278.5 KXX80452.1 - 1.2 9.7 3.7 0.46 11.0 0.6 2.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KXX80452.1 - 9.5 6.6 13.5 2.1 8.7 0.3 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Kelch_4 PF13418.6 KXX80453.1 - 1.7e-28 98.4 7.3 2.1e-08 34.0 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXX80453.1 - 2.3e-23 81.7 2.0 1.3e-06 28.2 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KXX80453.1 - 2.6e-23 81.5 2.0 0.00018 21.7 0.0 4.9 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXX80453.1 - 2.9e-20 71.6 0.6 0.00011 21.7 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KXX80453.1 - 3.1e-17 61.8 2.4 0.0014 18.5 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KXX80453.1 - 2.9e-16 59.3 5.2 0.00011 22.4 0.6 6.1 5 1 0 5 5 5 3 Galactose oxidase, central domain BTB PF00651.31 KXX80453.1 - 2.6e-09 37.3 0.0 4.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 KXX80454.1 - 4.8e-17 62.0 3.7 3.9e-05 23.8 0.2 4.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX80454.1 - 2.7e-16 59.7 18.6 0.00033 21.4 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 KXX80454.1 - 4.1e-06 26.8 0.2 0.00022 21.2 0.1 2.5 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXX80454.1 - 6.1e-06 25.4 0.1 0.00035 19.7 0.0 3.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIA PF03153.13 KXX80455.1 - 2.1e-89 301.4 9.6 2.5e-89 301.2 9.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 KXX80455.1 - 0.009 15.8 5.2 0.016 15.0 5.2 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3295 PF11702.8 KXX80455.1 - 0.018 14.4 2.5 0.013 14.8 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3295) BTV_NS2 PF04514.12 KXX80455.1 - 0.14 11.0 2.4 0.21 10.4 2.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YL1 PF05764.13 KXX80455.1 - 0.39 10.8 4.6 0.83 9.7 4.6 1.6 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 KXX80455.1 - 4.4 5.3 9.1 5.5 5.0 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi p450 PF00067.22 KXX80456.1 - 5.4e-70 236.4 0.0 6.8e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Get5_bdg PF16843.5 KXX80456.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein LptF_LptG PF03739.14 KXX80456.1 - 0.18 10.6 1.8 0.35 9.7 1.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Kinesin PF00225.23 KXX80458.1 - 2.6e-96 322.5 1.2 4.3e-96 321.7 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXX80458.1 - 2.4e-22 79.5 0.0 1.9e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KXX80458.1 - 0.02 14.7 1.5 0.02 14.7 1.5 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KXX80458.1 - 0.65 9.3 13.9 0.15 11.4 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_11 PF13086.6 KXX80458.1 - 1 9.1 8.5 0.18 11.6 3.7 2.2 2 0 0 2 2 2 0 AAA domain Tho2 PF11262.8 KXX80458.1 - 1.1 8.4 4.7 1.9 7.6 4.7 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FapA PF03961.13 KXX80458.1 - 2.2 6.8 6.2 2.4 6.7 2.0 2.7 3 0 0 3 3 3 0 Flagellar Assembly Protein A TFB6 PF17110.5 KXX80458.1 - 7.3 6.3 5.8 20 4.9 5.8 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Stk19 PF10494.9 KXX80459.1 - 6.5e-63 212.7 0.0 8.4e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 EccE PF11203.8 KXX80459.1 - 0.36 11.2 7.7 0.11 12.8 1.8 2.6 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE HTH_31 PF13560.6 KXX80459.1 - 1.3 9.4 8.2 3.1 8.2 2.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain DIOX_N PF14226.6 KXX80460.1 - 2.3e-13 50.9 0.0 2.5e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal zf-met2 PF12907.7 KXX80461.1 - 8.8e-15 54.6 3.7 1.5e-14 53.8 3.7 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KXX80461.1 - 0.00022 22.0 8.3 0.00045 21.0 8.3 1.5 1 0 0 1 1 1 1 4F5 protein family zf-C2H2_12 PF18658.1 KXX80461.1 - 0.034 13.7 0.2 0.047 13.3 0.2 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type HypA PF01155.19 KXX80461.1 - 0.046 13.7 0.3 0.054 13.5 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 KXX80461.1 - 0.17 12.8 1.3 0.24 12.4 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger NinE PF05322.11 KXX80461.1 - 0.34 10.8 2.4 6.7 6.7 0.3 2.2 1 1 1 2 2 2 0 NINE Protein DUF1479 PF07350.12 KXX80462.1 - 7.1e-109 364.3 0.0 4.5e-86 289.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) HHH PF00633.23 KXX80462.1 - 0.01 15.7 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PhyH PF05721.13 KXX80462.1 - 0.015 15.6 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) CDC37_N PF03234.14 KXX80462.1 - 0.094 13.6 0.3 0.21 12.5 0.3 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding 2OG-FeII_Oxy PF03171.20 KXX80463.1 - 8.6e-14 51.9 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXX80463.1 - 1.3e-10 42.1 0.0 2.1e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal RNA_pol_N PF01194.17 KXX80464.1 - 7.9e-18 64.5 0.1 1.1e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 KXX80465.1 - 1.7e-08 35.0 7.3 0.015 16.2 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat PD40 PF07676.12 KXX80465.1 - 0.0089 15.9 0.2 1.4 9.0 0.1 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat KcnmB2_inactiv PF09303.10 KXX80465.1 - 0.014 15.2 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 KCNMB2, ball and chain domain WD40_like PF17005.5 KXX80465.1 - 0.16 11.3 0.2 5.9 6.1 0.0 3.1 4 0 0 4 4 4 0 WD40-like domain MRJP PF03022.16 KXX80465.1 - 0.19 11.1 0.6 4.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Major royal jelly protein Methyltransf_16 PF10294.9 KXX80466.1 - 9.9e-22 77.5 0.0 1.9e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXX80466.1 - 2e-06 27.8 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SPACA9 PF15120.6 KXX80467.1 - 0.14 11.9 1.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 Bap31 PF05529.12 KXX80468.1 - 3e-50 169.6 9.1 3.8e-50 169.3 9.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KXX80468.1 - 4.3e-16 58.6 4.0 4.3e-16 58.6 4.0 2.2 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Csm1_N PF18504.1 KXX80468.1 - 0.016 15.5 0.4 0.016 15.5 0.4 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain GPS2_interact PF15784.5 KXX80468.1 - 0.37 11.3 2.7 0.29 11.6 0.9 1.7 1 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Sec8_exocyst PF04048.14 KXX80470.1 - 3.5e-50 169.6 0.3 8e-50 168.4 0.3 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KXX80470.1 - 5.2e-10 39.1 1.8 9.7e-10 38.2 1.8 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KXX80470.1 - 0.026 13.1 2.2 0.062 11.9 2.1 1.6 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 ATP-grasp_4 PF13535.6 KXX80470.1 - 0.085 12.4 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Swi5 PF07061.11 KXX80470.1 - 0.095 12.8 0.3 0.34 11.0 0.3 2.0 1 0 0 1 1 1 0 Swi5 Occludin_ELL PF07303.13 KXX80470.1 - 0.36 11.6 1.7 1.5 9.6 0.1 2.9 2 1 1 3 3 3 0 Occludin homology domain IZUMO PF15005.6 KXX80470.1 - 0.43 11.1 1.6 1.1 9.7 0.4 2.4 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated SMI1_KNR4 PF09346.10 KXX80471.1 - 1.2e-32 113.1 0.0 2.3e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) zf-C2H2 PF00096.26 KXX80472.1 - 0.58 10.7 12.4 0.56 10.8 0.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF629 PF04780.12 KXX80472.1 - 0.74 8.3 6.6 0.79 8.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 KXX80472.1 - 2 9.4 10.9 3.9 8.6 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger EST1_DNA_bind PF10373.9 KXX80473.1 - 2.6e-49 168.2 0.0 4e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KXX80473.1 - 1.2e-21 77.7 0.8 3.2e-21 76.4 0.8 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 Complex1_LYR_2 PF13233.6 KXX80474.1 - 2.1e-06 28.4 0.1 2.9e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXX80474.1 - 4.5e-06 26.6 0.1 9.6e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) G10 PF01125.17 KXX80475.1 - 1.7e-63 212.8 4.3 1.9e-63 212.6 4.3 1.0 1 0 0 1 1 1 1 G10 protein Auto_anti-p27 PF06677.12 KXX80475.1 - 0.019 15.1 1.9 0.019 15.1 1.9 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RNA_pol_L_2 PF13656.6 KXX80477.1 - 2.6e-30 104.0 0.0 3.5e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXX80477.1 - 1.6e-12 46.6 0.0 2.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SDA1 PF05285.12 KXX80477.1 - 0.0011 18.4 16.7 0.0011 18.4 16.7 1.1 1 0 0 1 1 1 1 SDA1 Na_trans_assoc PF06512.13 KXX80477.1 - 0.1 12.9 9.9 0.1 12.9 9.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated LAT PF15234.6 KXX80477.1 - 0.1 12.3 9.2 0.15 11.8 9.2 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Nop14 PF04147.12 KXX80477.1 - 0.2 9.8 22.7 0.24 9.6 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2151 PF10221.9 KXX80477.1 - 0.2 10.2 4.6 0.21 10.2 4.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RabGAP-TBC PF00566.18 KXX80477.1 - 0.23 11.1 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Zip PF02535.22 KXX80477.1 - 0.23 10.6 3.8 0.27 10.4 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Tankyrase_bdg_C PF15327.6 KXX80477.1 - 0.52 10.8 8.6 0.86 10.0 8.6 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain RPN2_C PF18004.1 KXX80477.1 - 0.95 9.4 14.1 1.6 8.7 14.1 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Rrn6 PF10214.9 KXX80477.1 - 1.3 7.4 4.9 1.3 7.5 4.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF913 PF06025.12 KXX80477.1 - 1.6 7.6 7.0 2.1 7.3 7.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 KXX80477.1 - 2 7.1 10.5 2.5 6.8 10.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DNA_pol_phi PF04931.13 KXX80477.1 - 2.1 6.3 25.6 2.7 6.0 25.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 KXX80477.1 - 3 6.9 14.5 4.1 6.5 14.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Usp PF00582.26 KXX80477.1 - 3.4 8.2 6.6 7.3 7.1 6.5 1.7 2 0 0 2 2 2 0 Universal stress protein family SAPS PF04499.15 KXX80477.1 - 3.8 6.2 9.7 4.1 6.1 9.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 KXX80477.1 - 4.5 7.0 14.8 6.1 6.6 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SURF2 PF05477.11 KXX80477.1 - 4.7 6.8 15.8 6.2 6.4 15.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) THOC2_N PF16134.5 KXX80477.1 - 5.6 5.5 7.4 6.8 5.2 7.4 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF4746 PF15928.5 KXX80477.1 - 6.1 6.2 22.5 8.1 5.8 22.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 KXX80477.1 - 6.3 5.5 10.5 7 5.3 10.5 1.1 1 0 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 KXX80477.1 - 7.2 4.2 8.6 8.7 4.0 8.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 KXX80477.1 - 7.5 4.7 16.6 9.9 4.3 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KXX80477.1 - 8.3 5.6 20.4 9.8 5.4 20.4 1.1 1 0 0 1 1 1 0 BUD22 UPF0220 PF05255.11 KXX80478.1 - 2.3e-55 186.6 2.9 2.7e-55 186.4 2.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) BNIP3 PF06553.12 KXX80478.1 - 0.075 12.7 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 BNIP3 DNApol_Exo PF18136.1 KXX80480.1 - 6.8e-102 340.4 0.0 1.1e-101 339.7 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KXX80480.1 - 3.2e-55 187.7 0.0 5.2e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1841 PF08897.11 KXX80480.1 - 0.13 12.3 2.4 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) MORN_2 PF07661.13 KXX80480.1 - 1.6 9.2 3.7 13 6.4 0.3 3.2 3 0 0 3 3 3 0 MORN repeat variant CH PF00307.31 KXX80481.1 - 3.3e-12 46.5 0.0 5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KXX80481.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.16 KXX80482.1 - 2e-10 41.4 0.4 6.3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2722 PF10846.8 KXX80483.1 - 0.00034 19.7 2.3 0.0005 19.1 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF5327 PF17261.2 KXX80483.1 - 0.057 14.2 4.6 0.16 12.8 4.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) TFIIA PF03153.13 KXX80483.1 - 0.084 12.9 8.1 0.13 12.3 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 KXX80483.1 - 0.22 11.5 2.1 0.36 10.8 2.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Androgen_recep PF02166.16 KXX80483.1 - 1.2 7.9 12.9 2.4 6.9 12.9 1.4 1 0 0 1 1 1 0 Androgen receptor PRIMA1 PF16101.5 KXX80483.1 - 2.1 8.4 7.3 4.4 7.4 7.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Spt20 PF12090.8 KXX80483.1 - 5.9 6.4 16.1 9.8 5.7 16.1 1.2 1 0 0 1 1 1 0 Spt20 family ABC2_membrane PF01061.24 KXX80484.1 - 1.6e-22 80.0 27.3 2.3e-22 79.4 27.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXX80484.1 - 3e-22 79.6 0.1 5.2e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXX80484.1 - 2.3e-06 27.6 0.1 3.1e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KXX80484.1 - 1.2e-05 25.3 0.0 0.014 15.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXX80484.1 - 0.00023 21.5 0.0 0.00053 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX80484.1 - 0.00037 20.9 0.1 0.00072 20.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KXX80484.1 - 0.0026 16.9 1.1 0.003 16.7 0.2 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.6 KXX80484.1 - 0.0038 17.5 0.7 0.012 15.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXX80484.1 - 0.0055 16.2 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 KXX80484.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KXX80484.1 - 0.011 15.3 0.2 0.02 14.5 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KXX80484.1 - 0.014 15.0 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXX80484.1 - 0.014 15.9 0.2 0.075 13.6 0.1 2.2 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KXX80484.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 KXX80484.1 - 0.023 14.1 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 KXX80484.1 - 0.026 14.3 0.4 0.11 12.1 0.0 2.2 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.15 KXX80484.1 - 0.03 14.3 0.1 0.091 12.7 0.1 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KXX80484.1 - 0.03 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXX80484.1 - 0.032 14.4 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXX80484.1 - 0.039 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KXX80484.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KXX80484.1 - 0.089 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KXX80484.1 - 0.098 12.4 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 KXX80484.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX80484.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KXX80484.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KXX80484.1 - 0.14 12.2 0.2 0.38 10.8 0.2 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zn_clus PF00172.18 KXX80485.1 - 4.1e-09 36.4 7.3 8.3e-09 35.4 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX80485.1 - 8.9e-06 24.9 0.0 4e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Nup192 PF11894.8 KXX80486.1 - 0 1478.5 0.0 0 1478.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Lipoprotein_Ltp PF07553.11 KXX80486.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein zf-C3HC4_3 PF13920.6 KXX80487.1 - 1.2e-10 41.1 6.8 1.8e-10 40.5 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX80487.1 - 1.2e-07 31.5 9.6 2e-07 30.7 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXX80487.1 - 2e-07 30.7 8.4 2e-07 30.7 8.4 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXX80487.1 - 3.3e-07 30.1 8.3 5.3e-07 29.5 8.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXX80487.1 - 4.1e-07 30.2 9.0 8.2e-07 29.3 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXX80487.1 - 6.5e-07 29.1 9.1 1.1e-06 28.4 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX80487.1 - 3.4e-06 27.0 7.5 8.5e-06 25.7 3.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXX80487.1 - 0.00027 20.9 2.6 0.00056 19.9 2.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXX80487.1 - 0.00097 18.9 5.3 0.0017 18.1 5.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXX80487.1 - 0.008 16.3 7.4 0.014 15.6 7.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXX80487.1 - 0.0098 16.2 4.7 0.024 14.9 4.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Gin PF10764.9 KXX80487.1 - 1.4 8.9 3.9 0.82 9.7 0.6 2.0 1 1 1 2 2 2 0 Inhibitor of sigma-G Gin FSA_C PF10479.9 KXX80487.1 - 1.5 6.8 4.8 2.6 6.1 4.8 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-RING_11 PF17123.5 KXX80487.1 - 2.1 8.2 11.1 0.29 10.9 6.4 2.0 2 0 0 2 2 2 0 RING-like zinc finger SSP160 PF06933.11 KXX80487.1 - 4.1 5.5 16.2 6.7 4.8 16.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 KXX80487.1 - 4.1 7.4 11.4 9 6.3 11.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WHIM1 PF15612.6 KXX80488.1 - 3.2e-07 29.7 0.0 7.3e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Pox_Ag35 PF03286.14 KXX80488.1 - 0.68 9.7 6.7 8.9 6.1 7.5 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nop14 PF04147.12 KXX80488.1 - 2.3 6.3 13.0 3.9 5.6 13.0 1.4 1 0 0 1 1 1 0 Nop14-like family Transglut_core PF01841.19 KXX80489.1 - 1.2e-11 45.0 0.2 2.9e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KXX80489.1 - 2.1e-08 33.7 0.1 4.8e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXX80489.1 - 6.7e-05 22.4 0.1 6.7e-05 22.4 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXX80489.1 - 0.015 15.1 0.2 0.036 13.9 0.2 1.7 1 0 0 1 1 1 0 Variant SH3 domain ABC_tran PF00005.27 KXX80490.1 - 5.6e-15 56.1 0.0 1.2e-08 35.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXX80490.1 - 2.4e-10 40.7 0.3 0.00019 21.4 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KXX80490.1 - 0.00078 17.1 0.2 0.001 16.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KXX80490.1 - 0.0012 18.5 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXX80490.1 - 0.0017 17.9 0.0 0.94 8.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXX80490.1 - 0.0089 16.6 0.1 0.012 16.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXX80490.1 - 0.01 16.3 0.1 0.075 13.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXX80490.1 - 0.011 16.0 0.9 0.038 14.2 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX80490.1 - 0.011 16.1 1.5 0.046 14.1 1.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXX80490.1 - 0.023 15.0 0.1 0.059 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KXX80490.1 - 0.028 14.1 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXX80490.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 KXX80490.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KXX80490.1 - 0.05 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXX80490.1 - 0.053 13.7 0.2 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KXX80490.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXX80490.1 - 0.16 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.21 KXX80490.1 - 0.17 11.3 0.4 0.29 10.6 0.4 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.12 KXX80490.1 - 0.2 11.6 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 NACHT domain RAI1 PF08652.11 KXX80491.1 - 1e-27 96.1 0.0 4.1e-27 94.2 0.0 2.1 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Trypan_PARP PF05887.11 KXX80491.1 - 0.68 9.9 6.8 1.4 8.9 6.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Corona_nucleoca PF00937.18 KXX80491.1 - 1.1 8.2 9.1 1.7 7.6 9.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pap_E4 PF02711.14 KXX80491.1 - 7.4 7.6 13.6 15 6.6 13.6 1.5 1 0 0 1 1 1 0 E4 protein Pkinase PF00069.25 KXX80492.1 - 2.4e-67 227.1 0.0 3.3e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80492.1 - 4.1e-47 160.6 0.0 6e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX80492.1 - 1.8e-05 23.8 0.2 4.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXX80492.1 - 0.0011 18.4 0.0 0.0043 16.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Chorion_2 PF03964.15 KXX80492.1 - 2.3 9.1 6.6 4.3 8.2 3.7 2.3 1 1 0 2 2 2 0 Chorion family 2 DUF3384 PF11864.8 KXX80493.1 - 9.4e-145 483.2 2.0 1.9e-144 482.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KXX80493.1 - 1.6e-52 177.8 0.0 4e-52 176.5 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KXX80493.1 - 1.4e-40 139.5 1.2 8.6e-36 123.8 0.0 3.6 4 0 0 4 4 4 3 Tuberin CAS_CSE1 PF03378.15 KXX80494.1 - 1.5e-184 613.7 0.0 2.6e-184 612.8 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KXX80494.1 - 4.3e-153 509.5 2.9 2.3e-152 507.1 3.7 1.8 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 KXX80494.1 - 1.1e-13 50.8 0.0 3.4e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXX80494.1 - 0.023 14.8 0.3 1.7 8.7 0.0 3.3 2 1 0 2 2 2 0 Exportin 1-like protein V-ATPase_H_N PF03224.14 KXX80494.1 - 0.12 11.6 1.0 0.47 9.7 0.3 2.3 1 1 2 3 3 3 0 V-ATPase subunit H ACDC PF14733.6 KXX80494.1 - 0.14 12.5 0.1 1.4 9.3 0.0 2.8 2 1 0 2 2 2 0 AP2-coincident C-terminal CENP-I PF07778.11 KXX80495.1 - 1.7e-33 116.1 0.0 3.9e-32 111.7 0.0 2.1 1 1 0 1 1 1 1 Mis6 Acetyltransf_1 PF00583.25 KXX80496.1 - 0.0037 17.5 0.0 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX80496.1 - 0.0066 16.4 0.0 0.066 13.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX80496.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PI3_PI4_kinase PF00454.27 KXX80497.1 - 1.2e-49 169.4 0.0 2.2e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KXX80497.1 - 8.3e-39 133.1 1.9 1.4e-38 132.4 0.0 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.23 KXX80497.1 - 4.7e-16 58.9 6.2 1.1e-15 57.7 6.2 1.6 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KXX80497.1 - 1.3e-11 44.1 0.1 4.3e-11 42.4 0.1 1.9 1 0 0 1 1 1 1 FATC domain SNF5 PF04855.12 KXX80498.1 - 1.2e-64 218.3 0.1 1.4e-63 214.9 0.1 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 KXX80499.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 RNA_pol_3_Rpc31 PF11705.8 KXX80499.1 - 0.015 15.6 5.6 0.015 15.6 5.6 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 KXX80499.1 - 3.1 7.5 6.9 5.5 6.6 6.9 1.4 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KXX80499.1 - 7.1 7.1 8.7 4.1 7.8 6.3 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD PF00628.29 KXX80500.1 - 2.6e-16 59.2 18.4 4.9e-09 35.9 8.9 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 KXX80500.1 - 0.0037 17.5 7.0 0.068 13.4 2.2 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-PHD-like PF15446.6 KXX80500.1 - 0.026 14.1 10.2 0.051 13.2 2.4 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 KXX80500.1 - 0.39 10.9 12.2 0.3 11.2 0.5 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger zf-HC5HC2H_2 PF13832.6 KXX80500.1 - 0.71 10.1 4.4 1.7 8.8 0.9 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain DUF2321 PF10083.9 KXX80500.1 - 0.82 9.3 2.9 1.6 8.3 2.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) PHD_4 PF16866.5 KXX80500.1 - 3.6 7.8 15.5 2.4 8.3 1.7 2.6 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KXX80500.1 - 4.4 7.3 16.0 1.3 9.0 1.0 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PDT PF00800.18 KXX80501.1 - 2.2e-52 177.6 0.0 2.8e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KXX80501.1 - 0.00048 19.8 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 ACT domain eRF1_2 PF03464.15 KXX80502.1 - 1.6e-47 161.1 0.1 2.9e-47 160.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXX80502.1 - 1.6e-40 138.1 0.7 3.1e-40 137.2 0.7 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KXX80502.1 - 6.7e-22 77.9 0.0 1.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KXX80502.1 - 1.1e-10 41.9 0.0 2.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KXX80502.1 - 2.9e-09 37.3 0.1 4.8e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF1770 PF08589.10 KXX80503.1 - 3.7e-35 120.9 0.1 4.6e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Ribosomal_L2_C PF03947.18 KXX80504.1 - 9.3e-42 142.2 4.9 1.6e-41 141.5 4.9 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXX80504.1 - 2.6e-15 56.1 0.2 6.2e-15 54.9 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 KXX80505.1 - 9.4e-68 228.7 0.0 1.1e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXX80505.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Acetyltransf_3 PF13302.7 KXX80506.1 - 9.4e-25 87.9 0.0 1.2e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX80506.1 - 0.00052 20.2 0.0 0.00072 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXX80506.1 - 0.062 13.4 0.0 0.098 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain COPIIcoated_ERV PF07970.12 KXX80507.1 - 4.3e-85 285.1 0.0 6.1e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXX80507.1 - 3.5e-31 107.4 0.0 9.9e-31 106.0 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Per1 PF04080.13 KXX80509.1 - 2.4e-104 348.7 11.3 2.8e-104 348.4 11.3 1.0 1 0 0 1 1 1 1 Per1-like family NUP214 PF16755.5 KXX80510.1 - 4.8e-06 26.0 0.0 9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KXX80510.1 - 0.0026 18.0 0.0 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG PF13634.6 KXX80510.1 - 0.0078 17.0 2.9 0.0078 17.0 2.9 5.3 4 1 1 5 5 5 2 Nucleoporin FG repeat region ER_lumen_recept PF00810.18 KXX80511.1 - 6.2e-44 150.4 9.5 9.8e-44 149.7 9.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF1516 PF07457.11 KXX80511.1 - 0.009 16.2 0.4 0.022 15.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) Pex2_Pex12 PF04757.14 KXX80511.1 - 0.03 13.9 1.7 0.051 13.2 1.7 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF2227 PF09988.9 KXX80511.1 - 0.064 13.1 4.1 0.16 11.8 4.0 1.7 1 1 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) PQ-loop PF04193.14 KXX80511.1 - 0.13 12.1 0.0 0.13 12.1 0.0 3.1 4 0 0 4 4 4 0 PQ loop repeat Sel1 PF08238.12 KXX80512.1 - 5.1e-13 49.2 4.2 0.00086 19.9 0.0 3.6 3 0 0 3 3 3 3 Sel1 repeat Proteasome PF00227.26 KXX80513.1 - 3e-46 157.3 0.1 3.8e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KXX80513.1 - 2.7e-13 49.1 0.5 2.7e-13 49.1 0.5 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DUF2722 PF10846.8 KXX80515.1 - 0.0022 17.0 17.5 0.0031 16.5 17.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Cmc1 PF08583.10 KXX80515.1 - 0.008 16.2 0.6 0.045 13.8 0.6 2.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_S64 PF08192.11 KXX80515.1 - 0.12 10.8 5.6 0.17 10.3 5.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Suf PF05843.14 KXX80515.1 - 0.51 10.3 14.3 1.1 9.2 14.3 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 KXX80515.1 - 0.95 7.7 19.0 0.24 9.6 15.4 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Rxt3 PF08642.10 KXX80515.1 - 1.8 9.4 5.1 0.38 11.5 1.2 1.9 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Spt20 PF12090.8 KXX80515.1 - 2.3 7.8 34.9 4 7.0 34.9 1.3 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 KXX80515.1 - 2.7 6.6 7.5 3.5 6.2 7.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCDC53 PF10152.9 KXX80515.1 - 2.8 8.3 17.7 0.47 10.8 12.7 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SKA1 PF07160.12 KXX80515.1 - 2.9 7.7 15.4 0.067 13.0 8.6 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Pex14_N PF04695.13 KXX80515.1 - 3.1 8.4 23.6 0.55 10.9 19.8 1.7 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.7 KXX80515.1 - 3.5 5.6 8.6 5.1 5.1 8.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_DNAp_acc PF04929.12 KXX80515.1 - 5 6.0 8.8 7.1 5.5 8.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CLN3 PF02487.17 KXX80515.1 - 6.4 5.7 4.6 12 4.8 4.6 1.4 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 KXX80515.1 - 8 5.1 12.6 1.3 7.7 8.7 1.6 2 0 0 2 2 2 0 Presenilin DUF2076 PF09849.9 KXX80515.1 - 8.5 6.3 27.1 0.023 14.8 17.0 1.8 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2076) ATP_sub_h PF10775.9 KXX80516.1 - 2.9e-26 91.2 0.6 4.4e-26 90.7 0.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h CDH-cyt PF16010.5 KXX80517.1 - 2e-19 70.0 2.2 3.8e-19 69.1 2.2 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KXX80517.1 - 1.9e-07 31.3 0.3 6.5e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.9 KXX80517.1 - 0.0017 18.1 5.5 0.0017 18.1 5.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) YtpI PF14007.6 KXX80517.1 - 0.13 12.4 2.8 0.44 10.7 0.6 2.4 2 0 0 2 2 2 0 YtpI-like protein ABC_tran PF00005.27 KXX80518.1 - 0.00043 20.8 0.0 0.0013 19.2 0.0 2.1 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 KXX80518.1 - 0.0031 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 KXX80518.1 - 0.0053 16.8 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX80518.1 - 0.0095 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KXX80518.1 - 0.017 15.7 0.2 0.044 14.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXX80518.1 - 0.034 14.5 0.0 0.16 12.3 0.0 2.1 3 1 0 3 3 3 0 AAA ATPase domain Prok-RING_1 PF14446.6 KXX80518.1 - 0.034 14.1 5.4 0.074 13.0 5.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AAA_29 PF13555.6 KXX80518.1 - 0.044 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXX80518.1 - 0.096 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain HGD-D PF06050.13 KXX80518.1 - 0.098 12.4 0.2 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component AAA_21 PF13304.6 KXX80518.1 - 0.12 12.2 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_pol_Rpb2_6 PF00562.28 KXX80519.1 - 4.3e-114 381.6 0.0 5.6e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXX80519.1 - 3.4e-35 121.4 0.0 5.3e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KXX80519.1 - 1.2e-28 99.1 0.0 2.6e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KXX80519.1 - 3e-26 92.2 0.0 5.9e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KXX80519.1 - 2.1e-24 85.3 0.0 4.5e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KXX80519.1 - 3.5e-16 59.4 0.0 1.6e-14 54.0 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Arf PF00025.21 KXX80520.1 - 1.1e-42 145.5 0.0 1.3e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXX80520.1 - 1.3e-19 70.3 0.0 1.5e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX80520.1 - 1.4e-14 54.4 0.0 2.3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KXX80520.1 - 2.1e-07 30.5 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KXX80520.1 - 1.8e-06 27.4 0.0 7.6e-06 25.3 0.0 2.1 2 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KXX80520.1 - 2.2e-06 27.8 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXX80520.1 - 7.5e-06 25.5 0.0 9.1e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KXX80520.1 - 0.019 14.5 0.2 0.041 13.4 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1979 PF09322.10 KXX80520.1 - 0.09 12.7 0.4 13 5.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) Dynamin_N PF00350.23 KXX80520.1 - 0.1 12.6 0.1 0.66 10.0 0.1 2.0 1 1 1 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 KXX80520.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Patatin PF01734.22 KXX80521.1 - 1.1e-16 61.7 0.0 1.7e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Corona_S2 PF01601.16 KXX80522.1 - 2.9 6.3 19.4 3.9 5.8 19.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ribosomal_S9 PF00380.19 KXX80523.1 - 7.6e-34 116.8 0.4 8.7e-34 116.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NAD_binding_8 PF13450.6 KXX80524.1 - 2e-10 40.7 0.1 4.3e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX80524.1 - 2.1e-07 30.4 0.9 3.9e-07 29.5 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXX80524.1 - 1.5e-06 27.9 0.4 2.2e-06 27.3 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXX80524.1 - 2.5e-06 27.4 0.0 4.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX80524.1 - 5.7e-05 22.0 0.4 8.6e-05 21.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXX80524.1 - 0.0001 21.6 0.1 0.00022 20.6 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX80524.1 - 0.00045 19.6 0.4 0.00071 18.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXX80524.1 - 0.0017 17.6 0.5 0.0082 15.4 0.5 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KXX80524.1 - 0.0022 18.5 0.1 0.0047 17.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXX80524.1 - 0.0039 16.4 0.0 2.7 7.1 0.1 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXX80524.1 - 0.014 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXX80524.1 - 0.021 14.1 0.1 0.18 11.1 0.1 2.0 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase IlvN PF07991.12 KXX80524.1 - 0.026 14.1 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 KXX80524.1 - 0.036 13.2 0.5 0.049 12.7 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Ppx-GppA PF02541.16 KXX80526.1 - 1.7e-27 96.6 0.0 8e-26 91.1 0.0 2.2 1 1 0 1 1 1 1 Ppx/GppA phosphatase family DUF3546 PF12066.8 KXX80528.1 - 8.2e-34 116.1 2.4 8.2e-34 116.1 2.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KXX80528.1 - 5.1e-15 56.4 1.3 1.5e-14 54.8 1.3 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KXX80528.1 - 4.7e-12 45.5 0.0 1.3e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DEAD PF00270.29 KXX80529.1 - 1.3e-48 165.1 0.0 1.5e-47 161.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX80529.1 - 9.6e-29 100.0 0.0 6.4e-28 97.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX80529.1 - 0.00014 21.9 0.0 0.0004 20.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 KXX80529.1 - 0.042 13.6 0.0 0.042 13.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3334) CMS1 PF14617.6 KXX80529.1 - 0.74 9.1 0.0 0.74 9.1 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.29 KXX80530.1 - 1.3e-40 138.9 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX80530.1 - 2.2e-07 30.6 0.0 5.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXX80530.1 - 6.5e-05 22.9 0.1 0.00043 20.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX80530.1 - 0.00012 22.4 0.0 0.0069 16.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KXX80530.1 - 0.00027 21.1 0.0 0.00083 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXX80530.1 - 0.00063 20.2 0.1 0.014 15.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KXX80530.1 - 0.0024 17.1 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXX80530.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KXX80530.1 - 0.023 15.0 0.0 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXX80530.1 - 0.051 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX80530.1 - 0.053 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KXX80530.1 - 0.064 13.0 0.0 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXX80530.1 - 0.067 12.7 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KXX80530.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXX80530.1 - 0.092 12.5 0.1 0.28 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXX80530.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXX80530.1 - 0.17 11.2 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 KXX80531.1 - 7.5e-149 496.5 16.5 8.5e-149 496.3 16.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 KXX80531.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X RRM_1 PF00076.22 KXX80532.1 - 1.1e-18 66.8 0.3 2.1e-18 65.9 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXX80532.1 - 1.1e-05 25.0 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXX80532.1 - 0.0024 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Frankia_peptide PF14407.6 KXX80532.1 - 0.0073 16.3 0.2 4.8 7.2 0.0 3.1 2 1 1 3 3 3 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PHM7_cyt PF14703.6 KXX80532.1 - 0.041 14.1 0.3 2.2 8.5 0.0 2.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter FliD_N PF02465.18 KXX80532.1 - 0.06 14.0 0.5 0.099 13.4 0.5 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Hemolysin_N PF12563.8 KXX80532.1 - 0.07 12.7 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Hemolytic toxin N terminal IFT20 PF14931.6 KXX80532.1 - 0.12 12.6 0.5 0.17 12.1 0.5 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 SOAR PF16533.5 KXX80532.1 - 0.38 10.7 2.2 1 9.4 0.7 2.0 1 1 1 2 2 2 0 STIM1 Orai1-activating region zf-C3HC4 PF00097.25 KXX80533.1 - 0.24 11.3 5.9 0.58 10.1 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 KXX80533.1 - 0.98 9.3 12.9 1.2 9.1 12.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tyosinase_C PF18132.1 KXX80534.1 - 2.7e-21 76.5 0.0 6.2e-21 75.3 0.0 1.6 2 0 0 2 2 2 1 Tyosinase C-terminal domain STIMATE PF12400.8 KXX80535.1 - 6.8e-28 97.7 10.9 6.3e-27 94.6 8.9 2.5 2 1 0 2 2 2 1 STIMATE family Pkinase PF00069.25 KXX80536.1 - 6.1e-68 229.0 0.0 8.4e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80536.1 - 3.4e-31 108.5 0.0 5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXX80536.1 - 6.1e-14 52.5 0.6 2.7e-13 50.4 0.6 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXX80536.1 - 4.7e-09 36.0 0.0 1.4e-08 34.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 KXX80536.1 - 7.6e-08 32.6 0.0 3.6e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 KXX80536.1 - 0.0014 17.7 0.3 0.0038 16.2 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXX80536.1 - 0.016 14.6 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E3_15_3 PF03307.14 KXX80536.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region APH PF01636.23 KXX80536.1 - 0.043 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KXX80536.1 - 0.069 12.8 0.8 5.6 6.5 0.1 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KXX80536.1 - 0.07 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SUZ PF12752.7 KXX80538.1 - 0.00029 21.5 10.1 0.00029 21.5 10.1 4.3 3 1 1 4 4 4 1 SUZ domain DUF812 PF05667.11 KXX80538.1 - 0.011 14.7 1.4 0.014 14.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) API5 PF05918.11 KXX80538.1 - 0.4 9.4 5.2 0.54 9.0 5.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) eIF3_subunit PF08597.10 KXX80538.1 - 3.3 7.5 16.2 3 7.7 4.6 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Fe_hyd_lg_C PF02906.14 KXX80539.1 - 2.2e-50 171.6 0.0 5.3e-50 170.4 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain zf-H2C2_2 PF13465.6 KXX80541.1 - 4.5e-07 30.0 9.7 3.3e-06 27.3 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 KXX80541.1 - 2e-05 25.1 4.7 0.15 12.7 0.0 2.8 2 1 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KXX80541.1 - 2.1e-05 24.4 0.5 0.061 13.3 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX80541.1 - 2.5e-05 24.5 0.3 2.5e-05 24.5 0.3 3.5 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX80541.1 - 0.0002 21.9 2.9 0.012 16.4 0.3 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXX80541.1 - 0.062 13.1 0.4 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KXX80541.1 - 0.29 11.5 1.1 6.4 7.2 0.2 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sina PF03145.16 KXX80541.1 - 0.3 11.0 6.8 1.3 8.9 1.9 2.1 1 1 1 2 2 2 0 Seven in absentia protein family zf-H2C2_5 PF13909.6 KXX80541.1 - 0.46 10.3 1.9 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain NUDE_C PF04880.13 KXX80541.1 - 1.5 9.3 4.2 0.71 10.3 0.1 2.3 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region LRR_6 PF13516.6 KXX80542.1 - 4.1e-11 42.0 9.7 0.041 13.9 0.0 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KXX80542.1 - 2.3e-05 24.6 15.2 0.082 13.4 0.0 5.2 5 0 0 5 5 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXX80542.1 - 0.00096 19.4 1.8 14 6.7 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 KXX80542.1 - 0.0025 17.5 15.1 1.2 9.0 0.1 5.3 4 1 0 4 4 4 2 Leucine rich repeat DUF2052 PF09747.9 KXX80542.1 - 1.1 9.3 18.0 1.6 8.8 18.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpc4 PF05132.14 KXX80542.1 - 1.3 9.4 5.6 2.2 8.7 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 KXX80542.1 - 1.5 7.8 18.9 2 7.3 18.9 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 KXX80542.1 - 1.6 8.5 14.6 2.6 7.8 14.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KXX80542.1 - 3.1 6.0 17.1 4.9 5.3 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 KXX80542.1 - 6.8 6.7 16.3 12 5.9 16.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 NOA36 PF06524.12 KXX80542.1 - 7.2 5.8 11.7 11 5.3 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein DARPP-32 PF05395.12 KXX80542.1 - 7.8 6.7 20.2 20 5.3 20.2 1.6 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 ATP11 PF06644.11 KXX80542.1 - 8.5 6.1 10.8 13 5.4 10.8 1.2 1 0 0 1 1 1 0 ATP11 protein Glyco_hydro_18 PF00704.28 KXX80544.1 - 5e-83 279.4 1.7 6e-83 279.1 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3153 PF11353.8 KXX80544.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) O_Spanin_T7 PF17531.2 KXX80545.1 - 0.23 11.5 1.2 0.89 9.7 1.2 2.0 1 0 0 1 1 1 0 outer-membrane spanin sub-unit Pkinase PF00069.25 KXX80547.1 - 1.5e-37 129.4 0.0 4.6e-37 127.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80547.1 - 3.9e-12 46.0 0.0 3.1e-11 43.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Tudor_3 PF18115.1 KXX80548.1 - 0.064 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain ATS3 PF06232.11 KXX80548.1 - 0.18 11.7 0.0 0.66 9.9 0.0 1.7 1 1 1 2 2 2 0 Embryo-specific protein 3, (ATS3) zf_CCCH_4 PF18345.1 KXX80549.1 - 1.1e-05 25.3 5.3 2e-05 24.5 5.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KXX80549.1 - 1.9e-05 24.3 1.6 3.2e-05 23.6 1.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KXX80549.1 - 0.00051 20.7 0.5 0.0023 18.6 0.5 2.2 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KXX80549.1 - 0.0028 18.1 1.6 0.0049 17.3 1.6 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KXX80549.1 - 0.0038 17.1 2.4 0.0075 16.2 2.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KXX80549.1 - 0.022 15.0 0.5 0.048 13.9 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger containing family PBP1_TM PF14812.6 KXX80549.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec1 PF00995.23 KXX80550.1 - 4.1e-130 435.7 0.0 4.7e-130 435.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family IFT43 PF15305.6 KXX80550.1 - 0.061 13.5 3.6 0.13 12.4 1.5 2.2 2 0 0 2 2 2 0 Intraflagellar transport protein 43 Chitin_synth_1 PF01644.17 KXX80551.1 - 8.4e-75 250.2 0.2 1.2e-74 249.7 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXX80551.1 - 3.8e-29 100.4 0.0 7.7e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXX80551.1 - 1.9e-20 73.0 8.8 3.2e-17 62.3 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXX80551.1 - 9.7e-06 25.6 3.8 9.7e-06 25.6 3.8 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DUF3602 PF12223.8 KXX80552.1 - 7.2e-20 71.4 1.7 7.2e-20 71.4 1.7 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) RRM_1 PF00076.22 KXX80553.1 - 7.9e-35 118.5 0.1 4e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX80553.1 - 1.3e-10 41.2 0.1 0.00057 19.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXX80553.1 - 4.4e-06 26.6 0.1 0.035 14.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif P22_CoatProtein PF11651.8 KXX80553.1 - 0.049 12.2 10.1 0.081 11.5 10.1 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 GEMIN8 PF15348.6 KXX80553.1 - 3.4 7.9 10.4 18 5.5 3.0 3.2 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 Flavoprotein PF02441.19 KXX80553.1 - 9 6.0 6.2 16 5.2 6.2 1.4 1 0 0 1 1 1 0 Flavoprotein RabGAP-TBC PF00566.18 KXX80554.1 - 6.8e-50 169.7 0.0 1.3e-49 168.8 0.0 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SHNi-TPR PF10516.9 KXX80555.1 - 1.3e-16 59.7 0.1 7.2e-16 57.4 0.1 2.4 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 KXX80555.1 - 0.0002 21.6 4.6 0.012 15.9 1.8 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX80555.1 - 0.00037 21.1 2.2 0.00037 21.1 2.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 KXX80555.1 - 0.0042 17.0 3.4 0.011 15.7 3.4 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXX80555.1 - 0.026 15.0 1.9 0.026 15.0 1.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXX80555.1 - 0.15 12.5 0.9 3.7 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L29 PF00831.23 KXX80555.1 - 0.15 12.0 4.7 0.84 9.6 1.0 3.3 2 1 1 3 3 3 0 Ribosomal L29 protein ANAPC3 PF12895.7 KXX80555.1 - 0.35 11.1 3.7 3.3 8.0 2.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KXX80555.1 - 1.7 8.6 6.2 1.4 8.9 1.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXX80555.1 - 8.9 6.7 17.1 0.46 10.7 3.6 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Flavoprotein PF02441.19 KXX80556.1 - 3.5e-27 95.1 0.0 5.5e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Btz PF09405.10 KXX80557.1 - 7.8e-29 100.6 2.5 7.8e-29 100.6 2.5 1.9 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.23 KXX80558.1 - 6.9e-13 48.7 0.2 2.3e-09 37.1 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KXX80558.1 - 0.13 12.8 0.1 0.98 10.0 0.1 2.1 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Aconitase PF00330.20 KXX80559.1 - 4.3e-146 487.5 0.0 5.6e-146 487.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXX80559.1 - 1.1e-37 129.3 0.0 1.9e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KXX80559.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Rad52_Rad22 PF04098.15 KXX80560.1 - 5e-60 201.9 0.0 6.6e-60 201.5 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Pkinase PF00069.25 KXX80561.1 - 1.8e-09 37.4 0.0 4.5e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KXX80561.1 - 7.5e-08 32.0 2.3 0.064 13.5 0.0 5.4 5 1 1 6 6 6 3 HEAT repeat Cnd1 PF12717.7 KXX80561.1 - 2.1e-06 27.9 0.0 4.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 KXX80561.1 - 2.8e-05 23.5 0.0 5.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KXX80561.1 - 0.00051 20.4 0.4 0.026 14.9 0.1 3.4 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KXX80561.1 - 0.002 18.6 0.0 5.6 7.6 0.0 3.5 2 1 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.6 KXX80561.1 - 0.0079 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Adaptin_N PF01602.20 KXX80561.1 - 0.17 10.4 0.1 0.38 9.3 0.1 1.4 1 1 0 1 1 1 0 Adaptin N terminal region N_BRCA1_IG PF16158.5 KXX80562.1 - 7.5e-34 116.5 0.0 2.1e-33 115.1 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KXX80562.1 - 1.5e-17 63.1 61.4 3.8e-06 26.6 5.5 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type Baculo_IE-1 PF05290.11 KXX80562.1 - 0.0067 16.4 0.6 0.0067 16.4 0.6 2.3 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) C1_2 PF03107.16 KXX80562.1 - 2 8.8 52.1 0.22 11.9 11.2 4.7 4 0 0 4 4 4 0 C1 domain UPF0052 PF01933.18 KXX80563.1 - 6.1e-59 199.6 0.0 7.9e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Cut8 PF08559.10 KXX80564.1 - 6.2e-81 271.6 0.0 7.7e-81 271.2 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein RRM_1 PF00076.22 KXX80565.1 - 1.3e-21 76.2 0.1 1.2e-13 50.6 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX80565.1 - 0.0021 18.1 0.0 0.087 13.0 0.1 2.8 2 0 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 KXX80565.1 - 0.024 14.7 0.3 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 KXX80565.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PhyH PF05721.13 KXX80566.1 - 2.4e-60 204.4 0.0 2.9e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Rho_N PF07498.12 KXX80567.1 - 0.0061 16.5 0.3 0.013 15.5 0.3 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain FAM176 PF14851.6 KXX80567.1 - 0.042 13.5 0.9 0.063 12.9 0.9 1.2 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 KXX80567.1 - 0.047 14.1 0.8 0.082 13.3 0.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 KXX80567.1 - 0.062 13.1 2.6 0.09 12.6 2.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 KXX80567.1 - 1.2 8.5 6.2 1.6 8.1 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4637 PF15470.6 KXX80567.1 - 1.5 8.5 6.1 2.7 7.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Adeno_terminal PF02459.15 KXX80567.1 - 9.2 4.5 5.6 13 4.1 5.6 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein WD40 PF00400.32 KXX80568.1 - 1.7e-39 133.1 14.7 1.6e-09 38.2 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX80568.1 - 5.1e-12 45.9 0.6 0.0046 17.2 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX80568.1 - 1.7e-08 33.8 0.6 0.97 8.3 0.0 4.6 2 2 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXX80568.1 - 3e-06 26.2 2.3 0.084 11.5 0.1 4.4 2 1 1 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KXX80568.1 - 0.00059 18.9 2.8 0.0012 17.8 0.1 2.6 3 1 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KXX80568.1 - 0.00061 18.2 0.0 0.0038 15.6 0.0 2.1 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KXX80568.1 - 0.061 12.7 0.0 9.6 5.4 0.0 3.2 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal USP7_C2 PF14533.6 KXX80568.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal Hira PF07569.11 KXX80568.1 - 0.18 11.5 0.5 27 4.4 0.0 2.8 1 1 2 3 3 3 0 TUP1-like enhancer of split FHA PF00498.26 KXX80569.1 - 5.3e-13 49.1 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain SDA1 PF05285.12 KXX80569.1 - 0.041 13.3 20.3 0.08 12.4 20.3 1.4 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 KXX80569.1 - 1.5 8.3 19.0 3.3 7.2 19.0 1.6 1 0 0 1 1 1 0 PPP4R2 IFRD PF05004.13 KXX80570.1 - 1.4e-79 267.4 6.6 1.8e-79 267.1 6.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 KXX80570.1 - 0.01 16.3 0.0 40 4.9 0.0 4.1 5 0 0 5 5 5 0 HEAT-like repeat HET-s_218-289 PF11558.8 KXX80570.1 - 0.047 13.7 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 Het-s 218-289 Apolipoprotein PF01442.18 KXX80570.1 - 0.33 10.8 3.4 2.6 7.9 0.7 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Transket_pyr PF02779.24 KXX80571.1 - 0.057 13.1 1.2 0.35 10.5 0.2 2.4 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain DUF2613 PF11021.8 KXX80571.1 - 9.8 6.4 7.0 7.5 6.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) AhpC-TSA_2 PF13911.6 KXX80573.1 - 1.1e-17 64.2 0.0 2.5e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXX80573.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family UPF1_Zn_bind PF09416.10 KXX80574.1 - 2.1e-71 238.8 4.8 6.6e-71 237.2 1.7 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KXX80574.1 - 4e-62 209.4 0.0 1.1e-61 207.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXX80574.1 - 3.1e-54 184.5 4.5 6.5e-31 108.1 0.4 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KXX80574.1 - 7.7e-34 115.8 0.0 1.5e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KXX80574.1 - 7.2e-13 48.7 0.5 1.1e-11 44.8 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX80574.1 - 1.7e-10 41.4 0.2 1.4e-09 38.5 0.2 2.5 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KXX80574.1 - 9.1e-06 25.8 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXX80574.1 - 2.2e-05 24.4 0.1 5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 KXX80574.1 - 3.8e-05 23.6 0.4 0.35 10.6 0.0 3.2 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXX80574.1 - 0.00019 20.8 0.3 0.0058 15.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KXX80574.1 - 0.00029 20.1 0.2 0.22 10.7 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 KXX80574.1 - 0.00029 20.4 0.1 0.0072 15.9 0.2 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KXX80574.1 - 0.0057 16.4 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KXX80574.1 - 0.0063 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ATPase PF06745.13 KXX80574.1 - 0.0082 15.5 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.6 KXX80574.1 - 0.012 15.8 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KXX80574.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ribosomal_S13_N PF08069.12 KXX80574.1 - 0.071 13.2 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA PF00004.29 KXX80574.1 - 0.11 13.0 0.0 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXX80574.1 - 0.15 11.5 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.14 KXX80574.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PBP1_TM PF14812.6 KXX80574.1 - 0.31 11.5 1.5 0.83 10.1 1.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Brix PF04427.18 KXX80575.1 - 3.9e-30 105.4 0.2 4.8e-30 105.1 0.2 1.1 1 0 0 1 1 1 1 Brix domain Syntaxin PF00804.25 KXX80576.1 - 3.8e-19 69.1 6.1 3.8e-19 69.1 6.1 1.9 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KXX80576.1 - 6.4e-11 42.1 0.8 1.7e-10 40.7 0.8 1.8 1 0 0 1 1 1 1 SNARE domain SKA2 PF16740.5 KXX80576.1 - 0.04 13.7 0.6 0.04 13.7 0.6 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF2951 PF11166.8 KXX80576.1 - 0.097 12.9 0.3 0.097 12.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF3018 PF11455.8 KXX80576.1 - 2 8.4 5.7 1.9 8.5 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3018) Synaptobrevin PF00957.21 KXX80576.1 - 2.4 8.0 8.0 0.27 11.0 2.2 2.3 2 1 1 3 3 3 0 Synaptobrevin Baculo_PEP_C PF04513.12 KXX80576.1 - 3 7.9 16.2 1.7 8.7 2.8 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KXX80576.1 - 5.9 7.6 14.7 0.082 13.5 2.2 3.2 2 1 2 4 4 4 0 SlyX FUSC PF04632.12 KXX80576.1 - 6.3 5.2 10.8 4.2 5.8 3.6 2.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.7 KXX80576.1 - 7.1 6.8 8.2 2 8.6 0.6 2.3 2 0 0 2 2 2 0 Tropomyosin like BRE1 PF08647.11 KXX80576.1 - 8.1 6.6 9.8 2.9 8.0 0.5 3.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase TPR_1 PF00515.28 KXX80577.1 - 7.8e-46 152.1 33.0 3.2e-06 26.7 0.1 11.3 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 KXX80577.1 - 8.4e-40 131.7 29.7 4e-05 23.4 0.0 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.6 KXX80577.1 - 5.7e-24 84.5 13.6 2.1e-06 28.3 0.3 7.6 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXX80577.1 - 6.5e-22 76.9 25.4 1.9e-05 24.3 0.0 9.1 5 2 4 9 9 9 6 TPR repeat TPR_17 PF13431.6 KXX80577.1 - 8.5e-21 72.8 11.7 0.0032 17.7 0.6 8.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX80577.1 - 2.9e-19 67.6 33.4 0.00015 21.7 0.0 11.3 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXX80577.1 - 2.3e-18 66.2 30.8 0.0043 17.3 0.7 8.7 3 2 4 8 8 8 7 Tetratricopeptide repeat TPR_9 PF13371.6 KXX80577.1 - 5.3e-14 52.1 12.7 2.1e-06 27.8 0.2 6.3 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXX80577.1 - 3.9e-13 49.7 24.2 0.00066 20.1 1.3 7.8 4 2 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXX80577.1 - 3.2e-10 39.9 21.2 0.012 16.4 0.2 9.5 5 3 6 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXX80577.1 - 3.7e-09 36.0 26.0 0.098 12.7 0.2 9.5 9 1 1 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX80577.1 - 5.4e-09 36.1 18.9 0.21 11.8 0.0 5.7 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 KXX80577.1 - 8.9e-07 28.3 8.8 0.081 12.4 0.0 6.1 6 0 0 6 6 6 2 SHNi-TPR TPR_15 PF13429.6 KXX80577.1 - 2e-05 23.9 8.2 0.22 10.7 0.7 5.3 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX80577.1 - 0.00011 21.6 1.4 0.00011 21.6 1.4 2.4 2 1 0 2 2 1 1 MalT-like TPR region TPR_10 PF13374.6 KXX80577.1 - 0.00015 21.5 25.9 0.26 11.2 0.5 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat DUF3856 PF12968.7 KXX80577.1 - 0.001 19.1 5.7 5.4 7.1 0.0 5.6 4 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) preATP-grasp_3 PF18301.1 KXX80577.1 - 0.009 16.3 0.1 0.14 12.4 0.2 2.8 3 0 0 3 3 3 1 pre ATP-grasp 3 domain MIT PF04212.18 KXX80577.1 - 0.027 14.5 18.6 14 5.8 0.0 6.7 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TAF1_subA PF14929.6 KXX80577.1 - 0.21 11.0 1.6 0.29 10.5 0.2 1.8 2 1 0 2 2 2 0 TAF RNA Polymerase I subunit A Sel1 PF08238.12 KXX80577.1 - 0.28 11.9 3.2 1.8 9.3 0.1 3.8 3 0 0 3 3 3 0 Sel1 repeat NARP1 PF12569.8 KXX80577.1 - 0.29 10.0 24.8 0.099 11.5 0.5 4.4 2 2 0 4 4 4 0 NMDA receptor-regulated protein 1 MAS20 PF02064.15 KXX80577.1 - 0.77 9.9 14.6 3.9 7.6 2.1 4.5 5 1 1 6 6 5 0 MAS20 protein import receptor TPR_20 PF14561.6 KXX80577.1 - 2.6 8.4 10.2 14 6.1 0.3 4.9 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX80577.1 - 6.1 7.7 25.9 33 5.4 0.0 9.1 10 0 0 10 10 9 0 Tetratricopeptide repeat Aminotran_4 PF01063.19 KXX80578.1 - 8.2e-21 74.9 0.0 1.7e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV Myosin-VI_CBD PF16521.5 KXX80578.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Myosin VI cargo binding domain Actin PF00022.19 KXX80579.1 - 2.5e-127 424.9 0.0 1e-126 422.9 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXX80579.1 - 0.0052 15.6 0.0 1.1 8.0 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein Methyltransf_23 PF13489.6 KXX80581.1 - 5.3e-20 71.9 0.0 3.3e-19 69.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX80581.1 - 9.9e-15 55.0 0.0 2.9e-14 53.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX80581.1 - 2.7e-13 50.4 0.0 5.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX80581.1 - 1.7e-11 44.1 0.0 4.3e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX80581.1 - 2.8e-10 40.8 0.0 1.9e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXX80581.1 - 9.3e-05 22.0 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXX80581.1 - 0.00025 20.6 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXX80581.1 - 0.0016 18.0 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 KXX80581.1 - 0.0045 17.1 0.1 0.012 15.7 0.0 1.6 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXX80581.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KXX80581.1 - 0.028 13.7 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KXX80581.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXX80582.1 - 1.4e-15 57.1 0.0 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dak2 PF02734.17 KXX80582.1 - 0.014 15.3 0.4 0.032 14.2 0.3 1.7 1 1 0 1 1 1 0 DAK2 domain DUF3046 PF11248.8 KXX80582.1 - 0.068 13.6 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) HTH_24 PF13412.6 KXX80582.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 KXX80582.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix GHMP_kinases_N PF00288.26 KXX80583.1 - 1.3e-09 38.2 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXX80583.1 - 2.8e-06 27.6 0.0 6.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal p53-inducible11 PF14936.6 KXX80585.1 - 0.21 11.6 2.7 0.47 10.5 2.4 1.7 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 DUF1996 PF09362.10 KXX80586.1 - 1.3e-79 267.5 2.2 1.6e-79 267.2 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NAD_binding_2 PF03446.15 KXX80587.1 - 3e-31 108.7 0.1 3.6e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXX80587.1 - 0.00089 19.2 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXX80587.1 - 0.001 19.6 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KXX80587.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Dak1 PF02733.17 KXX80588.1 - 1e-102 343.3 0.1 2.8e-102 341.8 0.0 1.7 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KXX80588.1 - 3.9e-43 147.3 1.6 6.7e-43 146.6 1.6 1.4 1 0 0 1 1 1 1 DAK2 domain AIM3 PF17096.5 KXX80590.1 - 2.3 9.2 5.5 3.4 8.7 5.5 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DDR PF08841.10 KXX80591.1 - 0.15 11.0 1.3 0.28 10.1 1.3 1.4 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DAO PF01266.24 KXX80595.1 - 1.1e-30 107.5 0.0 1.3e-30 107.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX80595.1 - 3.8e-10 39.4 0.2 1.2e-07 31.2 0.2 2.4 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXX80595.1 - 2.4e-07 29.8 0.1 1e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXX80595.1 - 1.1e-06 28.2 0.0 1.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX80595.1 - 3.6e-06 26.5 0.0 1.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXX80595.1 - 6.1e-06 25.8 0.1 1.1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX80595.1 - 1.4e-05 24.5 0.1 5.3e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX80595.1 - 2.7e-05 24.3 0.1 7.3e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXX80595.1 - 3.2e-05 23.3 0.0 5.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXX80595.1 - 0.00028 20.1 0.0 0.00089 18.4 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A GDI PF00996.18 KXX80595.1 - 0.0021 16.7 0.0 0.0031 16.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_7 PF13241.6 KXX80595.1 - 0.017 15.5 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KXX80595.1 - 0.038 14.6 0.0 0.072 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX80595.1 - 0.067 12.2 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 KXX80595.1 - 0.17 11.0 0.0 5.3 6.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Clr5 PF14420.6 KXX80596.1 - 6.3e-19 68.0 2.9 1.3e-18 66.9 2.9 1.6 1 0 0 1 1 1 1 Clr5 domain RRN9 PF10680.9 KXX80596.1 - 0.045 14.0 0.1 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor EFP_N PF08207.12 KXX80596.1 - 0.07 13.2 0.5 0.19 11.8 0.2 1.8 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain AAA PF00004.29 KXX80597.1 - 1.8e-40 138.4 0.0 5.1e-40 137.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXX80597.1 - 5.2e-19 67.9 0.1 1.1e-18 67.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXX80597.1 - 5.9e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXX80597.1 - 3.8e-05 23.7 0.7 0.00019 21.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXX80597.1 - 0.00013 22.4 2.0 0.02 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXX80597.1 - 0.00034 20.4 0.0 0.0009 19.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXX80597.1 - 0.0011 19.1 0.2 0.0091 16.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KXX80597.1 - 0.008 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KXX80597.1 - 0.0083 15.6 0.2 0.078 12.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 KXX80597.1 - 0.0094 16.2 5.2 0.082 13.2 0.0 3.1 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 KXX80597.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXX80597.1 - 0.014 14.5 0.0 0.032 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF572 PF04502.13 KXX80597.1 - 0.067 12.8 4.1 0.1 12.2 4.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) IstB_IS21 PF01695.17 KXX80597.1 - 0.069 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXX80597.1 - 0.1 12.1 0.0 0.31 10.6 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KXX80597.1 - 0.1 12.3 0.1 0.41 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXX80597.1 - 0.43 10.3 5.5 0.48 10.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain Amino_oxidase PF01593.24 KXX80598.1 - 8.8e-41 140.6 0.1 1.1e-40 140.3 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX80598.1 - 4.6e-12 46.0 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX80598.1 - 0.0029 16.9 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX80598.1 - 0.0098 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXX80598.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 KXX80598.1 - 0.026 14.1 0.1 0.097 12.2 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase MCRA PF06100.11 KXX80598.1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 KXX80598.1 - 0.046 14.3 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX80598.1 - 0.14 10.8 0.0 0.29 9.8 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein F_bP_aldolase PF01116.20 KXX80599.1 - 6.1e-87 291.6 0.1 6.8e-87 291.5 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LacAB_rpiB PF02502.18 KXX80600.1 - 1.5e-43 148.2 1.1 1.7e-43 148.0 1.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase KptA_kDCL PF18176.1 KXX80600.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Arm-DNA-bind_3 PF13356.6 KXX80600.1 - 0.093 13.1 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 Arm DNA-binding domain TIM PF00121.18 KXX80602.1 - 1.5e-48 165.3 0.0 1.7e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase PRP4 PF08799.11 KXX80602.1 - 0.084 12.4 0.4 0.22 11.1 0.2 1.9 1 1 1 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like NmrA PF05368.13 KXX80603.1 - 1.5e-07 31.2 0.0 2.5e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX80603.1 - 3.4e-05 23.8 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Glyco_hydro_61 PF03443.14 KXX80605.1 - 3e-45 154.7 0.0 3.5e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KXX80606.1 - 9.8e-44 149.7 49.4 1.9e-42 145.5 49.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Phtf-FEM1B_bdg PF12129.8 KXX80606.1 - 0.051 13.4 0.5 0.27 11.0 0.5 2.1 1 1 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor SPT_ssu-like PF11779.8 KXX80606.1 - 0.06 13.0 0.4 0.06 13.0 0.4 2.5 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like MFS_1_like PF12832.7 KXX80606.1 - 0.063 12.1 21.4 0.14 11.0 10.2 2.9 1 1 2 3 3 3 0 MFS_1 like family Ish1 PF10281.9 KXX80608.1 - 4.4e-97 318.1 10.9 1.1e-14 54.4 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KXX80608.1 - 4e-13 48.8 0.0 0.22 11.3 0.0 8.4 9 0 0 9 9 9 3 SAP domain Slx4 PF09494.10 KXX80608.1 - 9.8e-08 31.8 2.2 0.81 9.7 0.0 6.3 6 1 0 6 6 6 2 Slx4 endonuclease HeH PF12949.7 KXX80608.1 - 2.1e-06 27.4 0.0 1.5 8.6 0.0 6.5 6 1 0 6 6 6 1 HeH/LEM domain SAM_2 PF07647.17 KXX80608.1 - 0.054 13.6 0.9 2.5 8.3 0.1 3.5 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) JmjC PF02373.22 KXX80608.1 - 0.091 13.2 0.1 0.82 10.1 0.0 2.4 2 0 0 2 2 2 0 JmjC domain, hydroxylase DUF2795 PF11387.8 KXX80608.1 - 0.85 9.9 4.4 8.7 6.6 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2795) Homeobox_KN PF05920.11 KXX80608.1 - 8.2 6.4 7.5 4.5 7.3 0.3 3.4 3 1 1 4 4 4 0 Homeobox KN domain DUF1996 PF09362.10 KXX80609.1 - 1.9e-82 276.8 3.0 2.3e-82 276.5 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MMR_HSR1 PF01926.23 KXX80610.1 - 1e-10 41.7 0.0 1e-10 41.7 0.0 2.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase Septin PF00735.18 KXX80610.1 - 0.0002 20.7 0.0 0.00066 19.0 0.0 1.8 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 KXX80610.1 - 0.00031 20.1 0.0 0.00092 18.6 0.0 1.8 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.6 KXX80610.1 - 0.00037 21.0 2.0 0.0013 19.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXX80610.1 - 0.00041 20.6 0.4 0.0021 18.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXX80610.1 - 0.0071 16.3 0.6 0.0071 16.3 0.6 2.8 2 1 0 2 2 2 1 RsgA GTPase DUF4974 PF16344.5 KXX80610.1 - 0.01 15.8 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) Dynamin_N PF00350.23 KXX80610.1 - 0.012 15.7 20.1 0.026 14.6 0.1 4.6 3 2 1 4 4 4 0 Dynamin family AAA_24 PF13479.6 KXX80610.1 - 0.026 14.3 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KXX80610.1 - 0.038 13.5 0.0 0.094 12.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.6 KXX80610.1 - 0.05 13.2 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 KXX80610.1 - 0.085 11.9 2.1 0.45 9.5 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KXX80610.1 - 0.37 11.3 0.1 0.37 11.3 0.1 2.9 3 2 0 3 3 3 0 ABC transporter CDC45 PF02724.14 KXX80610.1 - 1 7.5 12.3 1.6 6.9 12.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 KXX80610.1 - 7.7 6.8 17.7 4.7 7.5 10.9 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF948 PF06103.11 KXX80610.1 - 9.3 6.6 7.0 5.8 7.2 1.9 2.6 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) UBD PF16455.5 KXX80611.1 - 2.5e-38 130.5 0.0 5.1e-38 129.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KXX80611.1 - 3.9e-05 23.3 0.0 6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KXX80611.1 - 0.0003 20.8 0.1 0.00061 19.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXX80611.1 - 0.00037 21.0 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KXX80611.1 - 0.0063 16.3 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FAM199X PF15814.5 KXX80611.1 - 0.027 13.6 2.1 0.041 12.9 2.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X NAD_binding_11 PF14833.6 KXX80612.1 - 5.6e-29 100.9 1.3 3.7e-20 72.4 0.1 2.8 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pre-SET PF05033.16 KXX80612.1 - 3e-19 69.7 1.7 5.2e-19 68.9 1.7 1.4 1 0 0 1 1 1 1 Pre-SET motif SET PF00856.28 KXX80612.1 - 7.6e-19 68.7 0.0 3.3e-17 63.4 0.0 2.7 2 1 0 2 2 2 1 SET domain Ank_5 PF13857.6 KXX80613.1 - 5.1e-11 42.6 0.0 2.7e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX80613.1 - 6e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX80613.1 - 0.00041 20.9 0.0 0.00072 20.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX80613.1 - 0.0043 17.4 0.0 0.025 15.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ribonuc_P_40 PF08584.11 KXX80614.1 - 7.4e-54 183.0 0.0 1.3e-53 182.2 0.0 1.3 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit EF_assoc_1 PF08355.12 KXX80614.1 - 0.026 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 EF hand associated CCB1 PF12046.8 KXX80614.1 - 0.23 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Glycos_transf_3 PF00591.21 KXX80615.1 - 1.1e-60 205.4 0.0 3.7e-60 203.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KXX80615.1 - 1.1e-12 47.6 0.0 3.1e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain tRNA_lig_CPD PF08302.11 KXX80616.1 - 9.8e-88 293.9 0.0 1.4e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KXX80616.1 - 3.4e-86 288.6 0.0 5.7e-86 287.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KXX80616.1 - 3.6e-57 193.1 0.0 7e-57 192.2 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain Mago_nashi PF02792.14 KXX80617.1 - 5.7e-73 243.7 0.3 6.4e-73 243.5 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 KXX80618.1 - 1.6e-94 317.4 4.0 2.7e-94 316.6 4.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KXX80618.1 - 1.7e-58 196.5 0.2 3.7e-58 195.4 0.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KXX80618.1 - 6.9e-55 184.5 0.0 2.4e-54 182.7 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KXX80618.1 - 2.4e-14 53.7 5.7 1.9e-10 41.0 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXX80618.1 - 4.2e-09 36.7 2.8 0.02 15.3 0.0 5.5 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 KXX80618.1 - 0.00013 21.9 0.2 1.9 8.9 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 KXX80618.1 - 0.00013 22.1 0.0 0.00047 20.3 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform AP4E_app_platf PF14807.6 KXX80618.1 - 0.04 14.3 0.1 0.15 12.4 0.1 2.1 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF5071 PF16804.5 KXX80618.1 - 0.87 9.9 4.0 14 6.0 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5071) UPF0020 PF01170.18 KXX80619.1 - 2.5e-07 30.6 0.1 0.00091 19.0 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Vac_ImportDeg PF09783.9 KXX80620.1 - 1.1e-69 233.3 0.6 1.5e-69 233.0 0.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein GFA PF04828.14 KXX80621.1 - 1.2e-13 51.2 0.8 1.7e-13 50.7 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NUP PF06516.11 KXX80621.1 - 0.17 11.0 0.5 0.22 10.7 0.5 1.1 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) 3HCDH_N PF02737.18 KXX80622.1 - 5.8e-24 85.0 0.0 2.8e-23 82.7 0.0 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXX80622.1 - 1.2e-15 57.9 0.0 2.2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.14 KXX80622.1 - 0.0019 17.5 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXX80622.1 - 0.0042 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KXX80622.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 KXX80622.1 - 0.045 14.3 0.0 0.082 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXX80622.1 - 0.098 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Mito_carr PF00153.27 KXX80623.1 - 4.9e-65 215.5 3.0 5.7e-21 74.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SKG6 PF08693.10 KXX80625.1 - 2.5e-07 30.0 0.2 2.5e-07 30.0 0.2 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain GPI-anchored PF10342.9 KXX80625.1 - 0.03 15.1 0.1 0.058 14.2 0.1 1.5 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MtrF PF09472.10 KXX80625.1 - 0.2 11.1 1.2 0.37 10.2 1.2 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) LapA_dom PF06305.11 KXX80625.1 - 3.2 7.6 5.7 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Zip PF02535.22 KXX80626.1 - 4.2e-31 108.4 31.1 3.7e-15 56.0 2.8 4.3 5 0 0 5 5 5 3 ZIP Zinc transporter DUF1556 PF07590.11 KXX80626.1 - 0.88 9.9 2.5 1.1 9.6 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Fungal_trans PF04082.18 KXX80627.1 - 7.9e-19 67.7 0.3 3.9e-18 65.4 0.3 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX80627.1 - 3.7e-09 36.6 11.0 6.4e-09 35.8 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC4_WD40 PF12894.7 KXX80628.1 - 7.5e-12 45.4 0.1 0.0022 18.3 0.0 5.9 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX80628.1 - 5.7e-06 27.0 7.0 0.061 14.2 0.1 6.8 6 0 0 6 6 5 1 WD domain, G-beta repeat Abhydrolase_6 PF12697.7 KXX80628.1 - 1.7e-05 25.6 1.1 4e-05 24.3 0.1 2.2 2 1 1 3 3 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXX80628.1 - 2.6e-05 24.1 1.3 0.0001 22.1 1.3 1.9 1 1 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 KXX80628.1 - 3.2e-05 24.4 0.0 0.00012 22.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXX80628.1 - 0.00012 22.0 0.4 0.00031 20.7 0.4 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 KXX80628.1 - 0.00015 21.4 0.1 0.0004 20.0 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_33 PF13671.6 KXX80628.1 - 0.0015 18.7 0.1 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KXX80628.1 - 0.0015 17.7 0.6 0.031 13.5 0.5 2.7 2 1 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KXX80628.1 - 0.0032 17.7 0.1 0.011 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain LCAT PF02450.15 KXX80628.1 - 0.005 16.0 0.1 0.0097 15.1 0.1 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase AAA_19 PF13245.6 KXX80628.1 - 0.016 15.5 0.1 0.034 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXX80628.1 - 0.02 15.3 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hydrolase_4 PF12146.8 KXX80628.1 - 0.027 13.7 0.0 0.065 12.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ion_trans_N PF08412.10 KXX80628.1 - 0.043 13.4 0.7 2.1 8.0 0.0 3.3 3 0 0 3 3 3 0 Ion transport protein N-terminal Nbas_N PF15492.6 KXX80628.1 - 0.047 13.0 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal MeaB PF03308.16 KXX80628.1 - 0.054 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KXX80628.1 - 0.097 12.6 0.1 0.32 10.9 0.0 1.9 2 0 0 2 2 1 0 NTPase HrpB1_HrpK PF09613.10 KXX80628.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) AAA_7 PF12775.7 KXX80628.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KXX80628.1 - 0.18 12.3 0.0 0.53 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fructosamin_kin PF03881.14 KXX80629.1 - 8.6e-35 120.3 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXX80629.1 - 0.00044 20.2 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DNA_pol_phi PF04931.13 KXX80629.1 - 0.54 8.3 4.8 0.79 7.8 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KXX80629.1 - 2.4 7.4 4.9 3.9 6.7 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein PG_binding_2 PF08823.11 KXX80631.1 - 0.0047 17.2 0.0 0.018 15.3 0.0 2.0 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Melibiase_2 PF16499.5 KXX80633.1 - 8.3e-46 156.4 0.3 1.4e-45 155.7 0.3 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXX80633.1 - 2.2e-11 43.7 0.1 3.6e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXX80633.1 - 0.00057 18.9 0.0 0.00087 18.3 0.0 1.2 1 0 0 1 1 1 1 Melibiase GST_N_2 PF13409.6 KXX80634.1 - 1.6e-09 38.0 0.0 4e-09 36.6 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXX80634.1 - 3.3e-09 37.0 0.2 4.8e-08 33.3 0.2 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX80634.1 - 6.7e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX80634.1 - 0.00072 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX80634.1 - 0.0086 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXX80634.1 - 0.16 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RPN13_C PF16550.5 KXX80634.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 UCH-binding domain MFS_1 PF07690.16 KXX80635.1 - 6.5e-21 74.6 36.7 2.4e-19 69.5 9.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX80635.1 - 4.7e-07 29.0 2.8 9.2e-07 28.1 2.8 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter FAD_binding_4 PF01565.23 KXX80636.1 - 8.4e-23 80.6 2.8 1.5e-15 57.2 0.1 2.4 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.12 KXX80636.1 - 2e-17 63.0 0.8 3.5e-17 62.2 0.8 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXX80636.1 - 0.12 11.8 1.3 0.19 11.0 1.3 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HET PF06985.11 KXX80637.1 - 3.2e-28 98.9 0.0 7.8e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-XS PF03470.14 KXX80637.1 - 0.15 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 XS zinc finger domain DUF2846 PF11008.8 KXX80638.1 - 0.017 15.1 0.0 2 8.5 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2846) SLD5_C PF16922.5 KXX80638.1 - 0.042 14.0 0.0 0.19 11.9 0.0 2.1 2 1 0 2 2 2 0 DNA replication complex GINS protein SLD5 C-terminus PLDc_3 PF13918.6 KXX80638.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 PLD-like domain Pkinase PF00069.25 KXX80641.1 - 2.9e-34 118.7 0.0 5.1e-34 117.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80641.1 - 7.1e-16 58.3 0.0 1.3e-15 57.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX80641.1 - 0.00018 20.9 0.0 0.00038 19.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like ABC1 PF03109.16 KXX80641.1 - 0.016 15.3 0.3 0.031 14.4 0.3 1.4 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 KXX80641.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase HET PF06985.11 KXX80643.1 - 1.6e-31 109.6 0.0 3.2e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cyclase PF04199.13 KXX80643.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative cyclase DUF4360 PF14273.6 KXX80645.1 - 1.5e-32 112.9 0.6 1.8e-32 112.7 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Glyco_hydro_61 PF03443.14 KXX80646.1 - 3.1e-44 151.4 0.0 8.9e-39 133.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXX80646.1 - 3.6e-12 46.0 8.6 3.6e-12 46.0 8.6 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Aldo_ket_red PF00248.21 KXX80647.1 - 1.4e-66 224.7 0.0 1.7e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.10 KXX80648.1 - 3.4e-26 91.0 0.0 6.6e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.19 KXX80648.1 - 0.015 15.1 18.2 0.41 10.7 3.9 3.7 2 0 0 2 2 2 0 AT hook motif KIF1B PF12423.8 KXX80648.1 - 0.35 11.4 2.3 5.9 7.4 0.1 2.9 2 0 0 2 2 2 0 Kinesin protein 1B NUDIX PF00293.28 KXX80649.1 - 5.7e-05 23.2 0.0 0.00023 21.2 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain DJ-1_PfpI PF01965.24 KXX80650.1 - 1.2e-12 48.0 0.0 2e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family XLF PF09302.11 KXX80651.1 - 3.4e-55 187.0 0.0 4.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component WD40 PF00400.32 KXX80652.1 - 7.1e-11 42.5 7.2 0.00019 22.2 0.4 5.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX80652.1 - 0.001 19.3 0.2 0.058 13.7 0.1 3.4 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L37ae PF01780.19 KXX80652.1 - 0.0039 17.2 0.3 0.012 15.6 0.3 1.8 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-CHY PF05495.12 KXX80652.1 - 0.017 15.6 1.9 0.045 14.3 1.9 1.7 1 0 0 1 1 1 0 CHY zinc finger zinc_ribbon_16 PF17034.5 KXX80652.1 - 0.23 11.6 3.4 0.25 11.5 1.7 1.7 1 1 0 1 1 1 0 Zinc-ribbon like family DUF4379 PF14311.6 KXX80652.1 - 0.39 11.1 6.6 3.9 7.9 1.1 2.9 2 0 0 2 2 2 0 Probable Zinc-ribbon domain PHD PF00628.29 KXX80652.1 - 2.4 8.1 7.9 7.3 6.6 0.2 3.1 2 1 0 2 2 2 0 PHD-finger Ribosomal_S21e PF01249.18 KXX80653.1 - 1.9e-37 127.2 0.1 2.1e-37 127.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Forkhead PF00250.18 KXX80654.1 - 5.9e-21 74.5 1.1 1.2e-20 73.6 1.1 1.5 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 KXX80655.1 - 1.6e-64 217.3 7.7 2.1e-64 216.9 7.7 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KXX80655.1 - 8.4e-54 180.8 4.2 1.1e-50 170.7 1.6 2.4 2 0 0 2 2 2 2 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KXX80655.1 - 0.012 16.0 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) YolD PF08863.10 KXX80655.1 - 0.19 11.8 1.0 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 YolD-like protein DUF1087 PF06465.13 KXX80655.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF3110 PF11360.8 KXX80656.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) RHIM PF12721.7 KXX80657.1 - 0.81 10.2 3.0 20 5.7 0.9 2.8 2 1 0 2 2 2 0 RIP homotypic interaction motif cNMP_binding PF00027.29 KXX80658.1 - 4.5e-34 116.4 0.0 9.5e-19 67.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 KXX80658.1 - 4.4e-32 111.7 11.3 4.4e-32 111.7 11.3 2.9 3 0 0 3 3 3 1 Unstructured region on cNMP-binding protein F-box PF00646.33 KXX80658.1 - 3.1e-07 30.1 0.3 3.1e-07 30.1 0.3 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXX80658.1 - 2.2e-06 27.5 1.9 8e-06 25.7 1.9 2.0 1 0 0 1 1 1 1 F-box-like Cupin_3 PF05899.12 KXX80658.1 - 0.15 11.8 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Bax1-I PF01027.20 KXX80659.1 - 3.4e-35 121.8 8.3 5.1e-35 121.2 8.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.21 KXX80660.1 - 3.3e-60 202.7 0.2 3.8e-60 202.5 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SH3_1 PF00018.28 KXX80660.1 - 4.8 6.9 5.6 1.9 8.2 0.5 2.2 1 1 1 2 2 2 0 SH3 domain AAA PF00004.29 KXX80661.1 - 1.7e-15 57.6 0.0 3.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX80661.1 - 7.4e-05 23.0 1.7 0.015 15.6 0.1 2.9 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KXX80661.1 - 0.00012 22.5 0.1 0.00051 20.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXX80661.1 - 0.0023 17.7 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXX80661.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KXX80661.1 - 0.068 13.5 0.0 0.67 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ANXA2R PF15721.5 KXX80661.1 - 0.076 13.5 0.8 0.14 12.6 0.8 1.4 1 0 0 1 1 1 0 Annexin-2 receptor AAA_33 PF13671.6 KXX80661.1 - 0.12 12.5 0.0 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NUDIX PF00293.28 KXX80662.1 - 9.3e-19 67.8 0.2 1.1e-18 67.5 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXX80662.1 - 0.015 15.3 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 NUDIX domain LRR_6 PF13516.6 KXX80663.1 - 4.3e-05 23.2 5.4 0.21 11.7 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 KXX80663.1 - 5.2e-05 23.5 0.0 0.064 13.7 0.1 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXX80663.1 - 0.00017 21.7 1.6 2.2 9.2 0.0 4.8 6 0 0 6 6 6 1 Leucine Rich Repeat SAM_Ste50p PF09235.10 KXX80663.1 - 0.096 12.9 0.0 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Ste50p, sterile alpha motif LRR_8 PF13855.6 KXX80663.1 - 0.28 11.0 1.8 22 4.9 0.2 3.5 3 1 1 4 4 4 0 Leucine rich repeat AAA PF00004.29 KXX80664.1 - 1e-12 48.6 0.3 6e-12 46.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX80664.1 - 0.00043 20.6 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX80664.1 - 0.13 12.6 0.2 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX80664.1 - 1.4 9.3 3.1 2.7 8.3 1.2 2.3 1 1 1 2 2 2 0 AAA ATPase domain Gp_dh_C PF02800.20 KXX80665.1 - 1.3e-73 245.8 0.0 1.9e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXX80665.1 - 1.6e-38 131.1 0.0 3.2e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXX80665.1 - 0.0091 16.1 0.1 0.03 14.5 0.1 2.1 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus PTH2 PF01981.16 KXX80667.1 - 2.1e-45 153.8 0.3 2.9e-45 153.3 0.3 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Arb2 PF09757.9 KXX80668.1 - 2.6e-104 347.9 0.0 3.7e-104 347.5 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KXX80668.1 - 2e-78 264.0 0.0 3.3e-78 263.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DUF4719 PF15843.5 KXX80669.1 - 0.22 11.6 3.6 0.34 11.0 3.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4719) Ras PF00071.22 KXX80671.1 - 1.7e-48 164.3 0.9 5.8e-44 149.5 0.1 2.2 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KXX80671.1 - 3e-33 114.6 0.1 4.2e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX80671.1 - 1.2e-10 41.1 0.1 1.4e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXX80671.1 - 2.6e-07 30.7 0.1 3.4e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX80671.1 - 0.00089 19.2 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXX80671.1 - 0.0025 18.1 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DLIC PF05783.11 KXX80671.1 - 0.0029 16.5 0.1 0.27 10.0 0.0 2.1 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 KXX80671.1 - 0.0058 16.0 0.1 0.0086 15.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KXX80671.1 - 0.013 16.0 0.1 0.021 15.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KXX80671.1 - 0.018 14.6 0.1 0.14 11.7 0.1 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXX80671.1 - 0.021 15.2 0.0 0.032 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF1128 PF06569.11 KXX80671.1 - 0.033 14.2 0.1 0.067 13.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_24 PF13479.6 KXX80671.1 - 0.036 13.8 0.1 0.091 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KXX80671.1 - 0.037 13.4 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KXX80671.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KXX80671.1 - 0.082 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_21 PF13304.6 KXX80671.1 - 0.087 12.6 0.7 0.12 12.1 0.7 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FAD-SLDH PF12318.8 KXX80671.1 - 0.13 12.3 0.0 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_7 PF12775.7 KXX80671.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KXX80671.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.24 KXX80672.1 - 4e-10 39.5 0.4 8.7e-10 38.4 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.7 KXX80673.1 - 0.00017 21.4 0.7 0.00087 19.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXX80673.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box FIBP PF05427.11 KXX80673.1 - 0.24 10.6 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) Brix PF04427.18 KXX80674.1 - 1.8e-38 132.6 0.0 2.3e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain UbiA PF01040.18 KXX80675.1 - 2.1e-42 145.2 21.4 2.6e-42 144.9 21.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.25 KXX80676.1 - 3.8e-51 171.5 0.6 4.7e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 KXX80676.1 - 0.043 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MitMem_reg PF13012.6 KXX80677.1 - 6.5e-37 126.4 0.1 1.2e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXX80677.1 - 7.5e-32 109.8 0.0 1.6e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KXX80677.1 - 0.016 14.9 2.0 0.024 14.4 2.0 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain SWIM PF04434.17 KXX80678.1 - 0.0018 17.9 0.8 0.41 10.4 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger CRISPR_Cas6 PF10040.9 KXX80678.1 - 0.016 15.8 0.0 0.052 14.2 0.0 1.7 2 0 0 2 2 2 0 CRISPR-associated endoribonuclease Cas6 Coprogen_oxidas PF01218.18 KXX80679.1 - 3.8e-143 475.6 0.1 4.4e-143 475.4 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF4200 PF13863.6 KXX80679.1 - 4.4 7.7 6.1 3.3 8.2 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Atg8 PF02991.16 KXX80680.1 - 3e-51 172.0 0.2 3.5e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KXX80680.1 - 3.1e-06 27.5 0.0 3.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF5315 PF17242.2 KXX80681.1 - 2.1e-23 81.9 1.1 4.6e-23 80.8 1.1 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) SSP160 PF06933.11 KXX80681.1 - 2.4 6.3 6.9 4.2 5.5 6.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ADK PF00406.22 KXX80682.1 - 3.3e-58 196.1 0.0 4.3e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXX80682.1 - 1.6e-23 83.7 0.7 2.6e-23 83.0 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KXX80682.1 - 1.3e-17 63.4 0.0 4.7e-17 61.7 0.0 2.0 3 0 0 3 3 3 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KXX80682.1 - 5.4e-05 23.8 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXX80682.1 - 0.00028 21.1 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXX80682.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KXX80682.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase HOOK PF05622.12 KXX80683.1 - 4.5e-17 61.5 55.9 4.5e-17 61.5 55.9 2.9 1 1 1 2 2 2 1 HOOK protein YscO PF07321.12 KXX80683.1 - 0.0023 17.9 6.5 0.0023 17.9 6.5 6.5 2 2 2 5 5 5 2 Type III secretion protein YscO bZIP_1 PF00170.21 KXX80683.1 - 0.0047 17.0 2.4 0.0047 17.0 2.4 9.5 5 2 4 9 9 9 3 bZIP transcription factor CH PF00307.31 KXX80683.1 - 0.01 16.0 0.1 0.044 14.0 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain UXS1_N PF11803.8 KXX80683.1 - 1.6 9.2 4.8 0.38 11.1 0.7 2.2 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal Inhibitor_I9 PF05922.16 KXX80684.1 - 0.0067 17.1 0.1 0.0086 16.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 C2 PF00168.30 KXX80686.1 - 1.1e-29 102.8 0.0 1.1e-16 61.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Spt20 PF12090.8 KXX80686.1 - 1.4 8.5 9.0 3 7.4 9.0 1.5 1 0 0 1 1 1 0 Spt20 family DUF3043 PF11241.8 KXX80686.1 - 7.9 6.5 15.6 0.13 12.2 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Gon7 PF08738.10 KXX80687.1 - 2.3e-09 37.3 1.3 2.3e-09 37.3 1.3 1.6 1 1 1 2 2 2 1 Gon7 family DUF3684 PF12449.8 KXX80687.1 - 0.0033 15.3 0.6 0.0037 15.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Chi-conotoxin PF16981.5 KXX80687.1 - 0.24 11.7 0.3 0.41 10.9 0.2 1.4 1 1 0 1 1 1 0 chi-Conotoxin or t superfamily cobW PF02492.19 KXX80688.1 - 3.1e-34 118.1 0.0 3.8e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXX80688.1 - 1.3e-06 27.6 0.9 8.9e-06 24.9 0.9 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KXX80688.1 - 0.0067 16.9 0.0 0.0094 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXX80688.1 - 0.014 15.5 0.0 0.08 13.0 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KXX80688.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DJ-1_PfpI PF01965.24 KXX80689.1 - 1.1e-11 44.9 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family AARP2CN PF08142.12 KXX80690.1 - 1.2e-17 63.7 0.0 3.6e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KXX80690.1 - 0.029 13.9 0.0 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RIBIOP_C PF04950.12 KXX80691.1 - 1e-108 363.2 0.0 1.3e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal DNA_pol3_chi PF04364.13 KXX80691.1 - 0.21 11.8 1.0 22 5.2 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III chi subunit, HolC CPT PF07931.12 KXX80692.1 - 0.00053 19.9 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 KXX80692.1 - 0.0074 16.0 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KXX80692.1 - 0.01 16.4 0.0 0.034 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXX80692.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXX80692.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain BING4CT PF08149.11 KXX80693.1 - 1.1e-39 134.1 0.0 3.5e-36 122.9 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KXX80693.1 - 1.3e-07 31.8 0.0 1.5 9.1 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX80693.1 - 0.00014 22.6 0.0 0.013 16.3 0.0 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Glyco_hydro_15 PF00723.21 KXX80695.1 - 8.4e-104 347.8 0.0 9.9e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KXX80695.1 - 1.3e-32 111.5 0.1 2.7e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 Starch binding domain DUF3328 PF11807.8 KXX80696.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3301 PF11743.8 KXX80696.1 - 0.17 11.6 0.4 0.25 11.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) SART-1 PF03343.13 KXX80697.1 - 2.2e-185 617.9 56.0 2.6e-185 617.7 56.0 1.0 1 0 0 1 1 1 1 SART-1 family DUF4050 PF13259.6 KXX80698.1 - 7.8e-59 199.1 5.9 2.2e-58 197.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4050) SPX PF03105.19 KXX80699.1 - 3.2e-46 159.0 6.0 9.6e-34 117.9 2.1 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KXX80699.1 - 2.6e-33 115.8 40.3 4.6e-33 115.0 40.3 1.4 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXX80699.1 - 5.4e-26 91.5 60.1 2.5e-22 79.5 40.1 2.1 2 1 1 3 3 3 2 Citrate transporter RFX_DNA_binding PF02257.15 KXX80699.1 - 0.012 16.2 0.1 0.026 15.2 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Vps39_1 PF10366.9 KXX80700.1 - 1.2e-32 112.5 0.0 1.1e-31 109.3 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KXX80700.1 - 7.5e-29 100.4 0.0 2.1e-28 98.9 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KXX80700.1 - 2.5e-15 56.8 0.0 1.3e-14 54.5 0.0 1.9 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KXX80700.1 - 0.00023 21.1 0.8 0.001 19.0 0.3 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.28 KXX80700.1 - 0.039 13.8 4.6 0.56 10.1 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXX80700.1 - 0.17 12.0 0.9 16 5.9 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat bZIP_2 PF07716.15 KXX80701.1 - 0.15 12.2 1.4 0.35 11.0 1.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF1168 PF06658.12 KXX80702.1 - 0.17 11.7 6.8 0.39 10.5 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PAPA-1 PF04795.12 KXX80703.1 - 1.2e-29 102.9 4.7 1.2e-29 102.9 4.7 2.9 3 1 0 3 3 3 1 PAPA-1-like conserved region PI3K_1B_p101 PF10486.9 KXX80703.1 - 0.033 12.0 8.6 0.05 11.4 8.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Herpes_BLLF1 PF05109.13 KXX80703.1 - 7.5 4.4 8.9 9.7 4.0 8.9 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Pex14_N PF04695.13 KXX80704.1 - 4.8e-33 115.0 4.1 4.8e-33 115.0 4.1 3.8 3 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1387 PF07139.11 KXX80704.1 - 6.8 6.3 7.3 22 4.7 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) HbrB PF08539.11 KXX80705.1 - 2.7e-52 177.2 0.1 2.7e-52 177.2 0.1 2.1 3 0 0 3 3 3 1 HbrB-like EutC PF05985.11 KXX80705.1 - 0.098 11.9 0.8 0.17 11.1 0.8 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) LIM_bind PF01803.16 KXX80706.1 - 8.3e-74 248.1 0.1 8.3e-74 248.1 0.1 5.5 2 1 2 4 4 4 1 LIM-domain binding protein DUF4452 PF14618.6 KXX80707.1 - 5.7e-83 276.9 10.0 7e-83 276.6 10.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) BTB PF00651.31 KXX80708.1 - 3.1e-05 24.2 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain JmjC PF02373.22 KXX80709.1 - 5.6e-11 42.9 0.1 9.5e-10 38.9 0.1 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KXX80709.1 - 8.1e-10 38.8 8.3 8.1e-10 38.8 8.3 2.9 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KXX80709.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DUF3827 PF12877.7 KXX80710.1 - 0.31 9.3 3.4 0.38 9.1 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EF-hand_7 PF13499.6 KXX80711.1 - 1.2e-22 80.1 2.4 3.7e-12 46.5 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXX80711.1 - 2.8e-21 73.4 4.4 1.2e-05 24.5 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KXX80711.1 - 4.2e-18 64.0 7.7 1.4e-05 24.4 1.7 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KXX80711.1 - 1.1e-17 62.4 6.7 3.5e-05 23.4 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXX80711.1 - 2.5e-15 56.0 5.1 4.2e-07 29.7 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXX80711.1 - 1.6e-07 31.6 0.0 0.00021 21.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXX80711.1 - 0.00018 21.4 1.2 0.25 11.3 0.0 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KXX80711.1 - 0.0018 18.1 0.2 0.82 9.6 0.0 2.6 2 1 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KXX80711.1 - 0.051 13.9 0.0 2.5 8.5 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain EF-hand_14 PF17959.1 KXX80711.1 - 0.069 13.5 0.5 4.9 7.6 0.1 2.4 1 1 2 3 3 3 0 EF-hand domain DUF5580 PF17743.1 KXX80711.1 - 0.096 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) TauD PF02668.16 KXX80712.1 - 5.5e-45 154.2 1.6 6.5e-45 154.0 1.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cyclin_N PF00134.23 KXX80713.1 - 9e-12 44.8 0.1 2.4e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Las1 PF04031.13 KXX80713.1 - 0.031 14.4 0.8 6.5 6.9 0.1 2.8 2 1 1 3 3 3 0 Las1-like Cyclin_C_2 PF16899.5 KXX80713.1 - 0.66 10.4 0.1 0.66 10.4 0.1 2.3 3 0 0 3 3 3 0 Cyclin C-terminal domain Piwi PF02171.17 KXX80714.1 - 3.7e-06 26.4 0.0 6.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXX80714.1 - 0.00093 19.8 0.0 0.0031 18.1 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute Lgl_C PF08596.10 KXX80715.1 - 2.6e-116 388.6 0.0 4e-116 388.0 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KXX80715.1 - 2.9e-05 24.7 6.2 0.023 15.5 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX80715.1 - 0.0001 22.5 0.0 0.11 12.8 0.0 4.3 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 KXX80716.1 - 6.4e-40 137.2 28.9 8.9e-40 136.7 28.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.14 KXX80718.1 - 1.5e-56 191.6 0.1 2e-56 191.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXX80718.1 - 3.5e-11 42.9 13.5 1.2e-10 41.2 13.5 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain zf-C2H2_assoc PF16606.5 KXX80718.1 - 2.1 8.6 12.4 1.3 9.3 7.3 2.5 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers Clp1 PF06807.14 KXX80719.1 - 0.19 12.2 0.0 0.37 11.2 0.0 1.6 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 Glyco_hydro_61 PF03443.14 KXX80720.1 - 1.5e-56 191.6 0.1 2e-56 191.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXX80720.1 - 3.5e-11 42.9 13.5 1.2e-10 41.2 13.5 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain zf-C2H2_assoc PF16606.5 KXX80720.1 - 2.1 8.6 12.4 1.3 9.3 7.3 2.5 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers Gti1_Pac2 PF09729.9 KXX80721.1 - 2.5e-40 138.5 0.7 9.1e-36 123.6 0.1 3.3 2 2 1 3 3 3 2 Gti1/Pac2 family Macoilin PF09726.9 KXX80721.1 - 7.4 5.0 4.7 10 4.5 4.7 1.1 1 0 0 1 1 1 0 Macoilin family RasGAP PF00616.19 KXX80722.1 - 7.2e-59 199.0 0.0 2e-58 197.5 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KXX80722.1 - 4.1e-29 101.5 5.7 4.1e-29 101.5 5.7 2.7 3 0 0 3 3 3 1 RasGAP C-terminus FlxA PF14282.6 KXX80722.1 - 0.21 11.6 4.4 6.2 6.9 0.8 2.9 2 0 0 2 2 2 0 FlxA-like protein MFS_1 PF07690.16 KXX80723.1 - 1.9e-30 106.0 39.1 6e-30 104.3 35.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX80723.1 - 1.4e-05 24.1 8.6 1.4e-05 24.1 8.6 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter tRNA-synt_2 PF00152.20 KXX80724.1 - 1.8e-66 224.4 0.0 2.4e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2263 PF10021.9 KXX80725.1 - 7.1e-10 39.4 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SMC_N PF02463.19 KXX80727.1 - 3.2e-77 258.9 0.2 1.6e-76 256.6 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXX80727.1 - 1.5e-24 86.6 1.4 7.4e-24 84.3 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXX80727.1 - 5.5e-12 46.1 1.8 6.2e-05 23.0 0.0 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Filament PF00038.21 KXX80727.1 - 9.3e-05 22.2 45.7 9.3e-05 22.2 45.7 4.9 3 1 1 4 4 4 1 Intermediate filament protein Tektin PF03148.14 KXX80727.1 - 0.00015 20.6 15.5 0.00015 20.6 15.5 6.5 3 2 1 5 5 5 1 Tektin family AAA_29 PF13555.6 KXX80727.1 - 0.00061 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 KXX80727.1 - 0.0033 17.6 13.2 0.0033 17.6 13.2 7.8 3 2 6 9 9 9 1 Tropomyosin like DUF1664 PF07889.12 KXX80727.1 - 0.0075 16.3 5.6 0.0075 16.3 5.6 7.8 4 2 6 10 10 10 2 Protein of unknown function (DUF1664) BCL_N PF04714.13 KXX80727.1 - 0.15 12.2 0.2 0.85 9.7 0.2 2.4 1 0 0 1 1 1 0 BCL7, N-terminal conserver region ABC_tran PF00005.27 KXX80727.1 - 2 9.0 0.0 2 9.0 0.0 6.9 4 2 1 5 5 5 0 ABC transporter ELYS PF13934.6 KXX80728.1 - 1.8e-71 240.6 0.1 2.1e-71 240.4 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly HUN PF08729.10 KXX80729.1 - 3e-07 30.3 0.5 6.3e-07 29.3 0.5 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain SLX9 PF15341.6 KXX80729.1 - 0.29 11.5 0.1 0.29 11.5 0.1 3.1 3 1 0 3 3 3 0 Ribosome biogenesis protein SLX9 Glyco_hydro_3_C PF01915.22 KXX80730.1 - 5.4e-52 176.7 0.0 9.2e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX80730.1 - 3.2e-37 128.6 0.0 5.3e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX80730.1 - 2.1e-16 59.8 0.1 3.8e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1823 PF08853.11 KXX80730.1 - 0.088 13.0 0.1 61 3.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1823) ASF1_hist_chap PF04729.13 KXX80731.1 - 4.5e-72 241.0 0.1 5.9e-72 240.6 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone FlgD_ig PF13860.6 KXX80731.1 - 0.039 13.8 0.7 0.25 11.2 1.1 2.1 2 0 0 2 2 2 0 FlgD Ig-like domain Suf PF05843.14 KXX80732.1 - 5e-89 299.2 9.4 1.4e-86 291.2 0.0 3.5 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KXX80732.1 - 0.001 19.5 0.0 0.026 15.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX80732.1 - 0.0043 17.7 1.9 0.0086 16.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX80732.1 - 0.013 16.3 5.7 0.016 16.0 1.2 3.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Sigma70_ner PF04546.13 KXX80732.1 - 0.018 14.9 2.7 0.046 13.6 2.7 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region HAT PF02184.16 KXX80732.1 - 0.033 14.2 0.8 0.7 9.9 0.1 2.9 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat NRDE-2 PF08424.10 KXX80732.1 - 0.94 8.5 4.8 2.6 7.1 0.1 3.3 2 1 1 4 4 4 0 NRDE-2, necessary for RNA interference RMI1_N PF08585.12 KXX80733.1 - 1.8e-42 145.5 2.5 3.7e-34 118.4 0.3 2.0 2 0 0 2 2 2 2 RecQ mediated genome instability protein CENP-B_dimeris PF09026.10 KXX80734.1 - 0.93 9.9 2.7 14 6.1 0.0 3.0 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Neisseria_TspB PF05616.13 KXX80734.1 - 2.4 6.5 4.7 1.7 7.0 2.1 1.8 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein Fungus-induced PF10917.8 KXX80734.1 - 4 7.8 9.0 0.75 10.2 1.9 2.4 2 0 0 2 2 2 0 Fungus-induced protein XFP_N PF09364.10 KXX80735.1 - 1.2e-170 567.2 0.0 1.5e-170 566.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KXX80735.1 - 1.1e-82 276.1 0.0 1.6e-82 275.4 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KXX80735.1 - 3e-79 265.2 0.0 4.2e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain Pkinase_fungal PF17667.1 KXX80737.1 - 1.5e-126 422.5 0.0 1.9e-126 422.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KXX80737.1 - 5.5e-05 22.7 0.0 9.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain MauJ PF17419.2 KXX80737.1 - 0.0098 15.4 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Methylamine utilization protein MauJ Kdo PF06293.14 KXX80737.1 - 0.037 13.4 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX80737.1 - 0.052 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PUF PF00806.19 KXX80738.1 - 3.5e-09 35.8 0.0 8.2 6.3 0.0 6.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Lactamase_B_6 PF16661.5 KXX80739.1 - 1.5e-66 223.5 0.0 2.7e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KXX80739.1 - 2.6e-56 190.5 0.1 1.6e-55 187.9 0.0 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 KXX80739.1 - 4e-18 65.1 0.0 8.3e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 KXX80739.1 - 6.9e-16 58.5 0.0 2e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KXX80739.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXX80739.1 - 0.048 13.2 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Sec23_trunk PF04811.15 KXX80740.1 - 7.4e-53 179.6 0.0 5.3e-52 176.8 0.0 2.2 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXX80740.1 - 6.3e-23 80.6 0.0 1.2e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KXX80740.1 - 3.3e-15 55.8 4.1 6.8e-15 54.8 4.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KXX80740.1 - 1.2e-12 48.4 0.1 4.5e-12 46.6 0.1 1.9 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KXX80740.1 - 4.4e-06 26.5 0.0 1.3e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps51 PF08700.11 KXX80741.1 - 4.4e-23 81.2 0.0 7.1e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KXX80741.1 - 0.011 16.0 0.1 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Dor1 PF04124.12 KXX80741.1 - 0.05 12.3 0.2 0.076 11.7 0.2 1.2 1 0 0 1 1 1 0 Dor1-like family Nrap_D4 PF17405.2 KXX80742.1 - 1e-58 198.2 0.1 1.7e-58 197.5 0.1 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KXX80742.1 - 1.7e-58 196.9 0.1 6.9e-58 195.0 0.1 1.9 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KXX80742.1 - 1.1e-47 161.6 0.0 2.3e-45 154.1 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KXX80742.1 - 4.8e-42 143.6 0.0 1.4e-41 142.1 0.0 1.8 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KXX80742.1 - 4.3e-40 137.4 0.0 1e-39 136.2 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KXX80742.1 - 3.4e-37 127.7 0.0 6.8e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 BolA PF01722.18 KXX80743.1 - 1.8e-21 76.2 0.0 4.6e-21 74.9 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein CUTL PF16557.5 KXX80743.1 - 0.12 12.6 0.1 0.54 10.5 0.0 1.9 1 1 0 2 2 2 0 CUT1-like DNA-binding domain of SATB CorA PF01544.18 KXX80744.1 - 2.8e-10 40.0 0.2 5.8e-10 39.0 0.1 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein NIF3 PF01784.18 KXX80746.1 - 5.7e-63 212.8 0.0 7.1e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RPAP1_C PF08620.10 KXX80748.1 - 1.3e-27 95.7 0.0 2.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KXX80748.1 - 7.4e-20 70.5 1.4 1.3e-19 69.7 1.4 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal TPR_16 PF13432.6 KXX80749.1 - 1.7e-34 118.1 41.2 6.4e-08 33.1 0.0 12.4 11 2 1 12 12 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXX80749.1 - 4.4e-32 107.6 44.0 0.0023 17.9 0.0 16.4 17 0 0 17 17 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 KXX80749.1 - 8.6e-28 94.2 27.4 0.019 15.1 0.3 13.7 17 0 0 17 17 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 KXX80749.1 - 9.1e-28 96.6 33.0 1.5e-06 28.6 1.1 11.2 10 3 2 12 12 12 7 Tetratricopeptide repeat TPR_14 PF13428.6 KXX80749.1 - 1.1e-25 88.1 43.5 7.9e-05 23.2 0.0 16.4 13 5 5 18 18 16 5 Tetratricopeptide repeat TPR_1 PF00515.28 KXX80749.1 - 2.8e-24 83.9 35.3 0.00053 19.7 0.0 14.0 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_17 PF13431.6 KXX80749.1 - 3.9e-19 67.6 16.6 0.57 10.7 0.0 14.1 17 0 0 17 17 14 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXX80749.1 - 8.9e-14 50.9 30.3 0.017 14.8 0.0 10.5 10 1 1 11 11 10 4 TPR repeat TPR_12 PF13424.6 KXX80749.1 - 1.6e-12 47.6 60.4 0.00046 20.4 0.2 14.2 13 3 3 16 16 15 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXX80749.1 - 7.7e-10 38.1 32.9 0.0051 16.7 0.0 13.0 14 1 1 15 15 15 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXX80749.1 - 5.6e-09 36.1 30.1 0.024 15.3 0.0 14.0 17 0 0 17 17 15 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXX80749.1 - 4.6e-08 33.1 16.2 0.13 12.4 0.0 8.8 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_22 PF18833.1 KXX80749.1 - 8.4e-05 22.6 0.0 0.00026 21.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat ChAPs PF09295.10 KXX80749.1 - 0.0082 15.2 5.3 4.8 6.1 0.5 4.1 4 0 0 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_WDAD PF04053.14 KXX80749.1 - 0.031 13.3 0.1 0.072 12.1 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region DUF4192 PF13830.6 KXX80749.1 - 0.036 14.1 0.2 0.036 14.1 0.2 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4192) PPTA PF01239.22 KXX80749.1 - 0.068 12.9 0.3 65 3.5 0.0 4.1 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat DUF3239 PF11580.8 KXX80749.1 - 0.12 12.7 0.5 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3239) ANAPC3 PF12895.7 KXX80749.1 - 0.15 12.3 30.6 1.3 9.3 0.2 9.4 8 2 3 11 11 11 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 KXX80749.1 - 0.16 12.2 2.9 4.1 7.7 0.0 4.1 5 0 0 5 5 3 0 Tetratrico peptide repeat HrpB1_HrpK PF09613.10 KXX80749.1 - 0.19 11.4 5.5 56 3.4 0.0 5.4 5 1 1 6 6 6 0 Bacterial type III secretion protein (HrpB1_HrpK) Alkyl_sulf_dimr PF14863.6 KXX80749.1 - 0.22 12.0 4.6 1.3 9.5 1.3 3.4 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KXX80749.1 - 0.47 10.6 6.0 16 5.6 0.0 5.5 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat HemY_N PF07219.13 KXX80749.1 - 0.88 9.8 8.5 9.1 6.5 0.1 5.2 4 1 1 5 5 5 0 HemY protein N-terminus TPR_4 PF07721.14 KXX80749.1 - 1.6 9.5 38.7 57 4.8 0.2 10.9 12 0 0 12 12 8 0 Tetratricopeptide repeat ketoacyl-synt PF00109.26 KXX80750.1 - 3.3e-77 259.5 0.1 2.8e-76 256.4 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXX80750.1 - 2.1e-70 237.5 0.4 5.5e-70 236.1 0.3 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KXX80750.1 - 5.8e-65 219.7 0.0 8.1e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KXX80750.1 - 1.4e-53 181.5 0.0 2e-51 174.5 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KXX80750.1 - 9.9e-46 156.3 0.8 1.7e-45 155.5 0.8 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX80750.1 - 4.1e-40 138.2 0.1 8e-40 137.3 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX80750.1 - 7.6e-31 106.6 0.1 1.6e-29 102.3 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXX80750.1 - 2e-30 105.9 0.0 3.8e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KXX80750.1 - 2.2e-20 73.2 0.0 6.3e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXX80750.1 - 1.7e-15 57.1 1.5 6.4e-09 36.0 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 KXX80750.1 - 2.9e-14 53.1 0.0 1.8e-12 47.3 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KXX80750.1 - 3.1e-14 53.4 0.0 1.4e-13 51.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX80750.1 - 6.3e-14 51.9 0.1 5e-11 42.4 0.0 4.3 5 0 0 5 5 5 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KXX80750.1 - 6.3e-12 46.0 0.0 2e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX80750.1 - 7.1e-12 45.5 0.0 1.5e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXX80750.1 - 1.5e-10 41.5 0.0 3.8e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KXX80750.1 - 9.7e-08 31.9 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KXX80750.1 - 1.1e-06 27.9 0.0 3.1e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 KXX80750.1 - 2e-06 27.3 0.0 4.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KXX80750.1 - 8.5e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KXX80750.1 - 0.00026 20.5 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 KXX80750.1 - 0.00046 21.1 0.1 0.0042 18.0 0.0 2.8 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain ACP_syn_III PF08545.10 KXX80750.1 - 0.0037 17.1 0.7 0.011 15.6 0.7 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.9 KXX80750.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 KXX80750.1 - 0.072 14.1 1.4 2.9 8.9 0.0 3.9 4 0 0 4 4 3 0 Methyltransferase domain Methyltransf_33 PF10017.9 KXX80750.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Condensation PF00668.20 KXX80751.1 - 9.4e-249 825.6 0.0 6e-43 147.2 0.0 9.6 8 2 0 8 8 8 8 Condensation domain AMP-binding PF00501.28 KXX80751.1 - 5.9e-215 713.7 0.0 1.3e-71 241.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 KXX80751.1 - 3.8e-49 164.9 0.0 8e-15 54.9 0.0 5.7 5 0 0 5 5 5 4 Phosphopantetheine attachment site Transferase PF02458.15 KXX80751.1 - 3.9e-07 29.1 0.0 0.16 10.6 0.0 5.2 6 0 0 6 6 6 2 Transferase family AMP-binding_C PF13193.6 KXX80751.1 - 5.1e-07 30.6 0.1 0.075 14.0 0.0 3.1 2 1 0 2 2 2 2 AMP-binding enzyme C-terminal domain 2-oxoacid_dh PF00198.23 KXX80751.1 - 0.035 13.5 0.0 3.3 7.1 0.0 2.6 2 0 0 2 2 2 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) CorA PF01544.18 KXX80752.1 - 9.6e-10 38.2 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pyr_redox_2 PF07992.14 KXX80753.1 - 3.4e-22 79.0 0.0 3.4e-21 75.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX80753.1 - 1.5e-05 25.0 1.3 0.022 14.7 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXX80753.1 - 4.1e-05 22.8 0.5 0.00098 18.3 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 KXX80753.1 - 4.6e-05 22.7 0.5 0.00036 19.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KXX80753.1 - 0.00011 21.5 1.7 0.19 10.8 0.1 2.1 1 1 1 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 KXX80753.1 - 0.00016 21.4 2.5 0.0016 18.1 0.7 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXX80753.1 - 0.00039 19.8 0.1 0.1 11.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX80753.1 - 0.00064 18.5 0.1 0.0039 16.0 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KXX80753.1 - 0.00083 18.5 0.5 0.068 12.2 0.3 2.1 1 1 1 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXX80753.1 - 0.0021 18.2 0.1 0.0044 17.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX80753.1 - 0.048 12.9 0.2 0.21 10.8 0.1 2.1 3 0 0 3 3 3 0 FAD binding domain YqfD PF06898.11 KXX80754.1 - 0.21 10.4 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD MARVEL PF01284.23 KXX80754.1 - 8.7 6.4 11.9 34 4.5 11.9 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF2278 PF10042.9 KXX80756.1 - 6.5e-64 215.7 0.0 8.6e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.19 KXX80756.1 - 3.6e-09 37.0 0.1 9.2e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Lamin Tail Domain CorA PF01544.18 KXX80757.1 - 0.00053 19.4 3.9 0.00054 19.4 2.1 1.9 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein K-box PF01486.17 KXX80757.1 - 0.074 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 K-box region DUF3394 PF11874.8 KXX80757.1 - 0.11 12.2 0.1 15 5.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3394) Hepatitis_core PF00906.20 KXX80757.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Hepatitis core antigen Thioredoxin PF00085.20 KXX80759.1 - 1.1e-25 89.6 0.0 1.4e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXX80759.1 - 1.3e-06 28.0 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXX80759.1 - 2.1e-06 28.2 0.0 3.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXX80759.1 - 1.8e-05 25.0 0.0 5.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KXX80759.1 - 0.00014 21.6 0.1 0.00025 20.8 0.1 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXX80759.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KXX80759.1 - 0.00026 21.1 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 KXX80759.1 - 0.001 19.0 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KXX80759.1 - 0.001 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KXX80759.1 - 0.0015 18.4 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein HR_lesion PF05514.11 KXX80759.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 HR-like lesion-inducing Dfp1_Him1_M PF08630.10 KXX80760.1 - 4e-32 111.1 0.0 1.3e-31 109.4 0.0 2.0 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KXX80760.1 - 7.9e-21 73.9 0.0 1.3e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KXX80760.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain FAR1 PF03101.15 KXX80762.1 - 9.9e-08 32.6 0.3 2e-07 31.6 0.3 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain OTT_1508_deam PF14441.6 KXX80763.1 - 1.9e-19 69.4 0.0 3.6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase SOR_SNZ PF01680.17 KXX80764.1 - 2e-102 341.3 9.1 2.6e-102 340.9 9.1 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KXX80764.1 - 6.5e-06 25.6 14.2 0.0026 17.1 3.8 2.8 1 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KXX80764.1 - 6.4e-05 22.2 0.3 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KXX80764.1 - 0.0014 18.1 0.7 0.056 12.9 0.1 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 KXX80764.1 - 0.019 14.2 2.3 0.14 11.4 0.0 2.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KXX80764.1 - 0.36 10.1 14.8 0.21 10.9 4.9 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase DivIC PF04977.15 KXX80767.1 - 0.0097 15.7 9.8 1.1 9.1 0.2 4.0 3 1 1 4 4 4 2 Septum formation initiator Filament PF00038.21 KXX80767.1 - 0.029 14.0 12.0 0.033 13.8 8.0 2.5 2 1 0 2 2 2 0 Intermediate filament protein DUF5082 PF16888.5 KXX80767.1 - 0.056 13.7 6.8 2 8.7 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) SseC PF04888.12 KXX80767.1 - 0.12 11.9 7.1 1 8.9 0.2 2.7 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family CENP-F_leu_zip PF10473.9 KXX80767.1 - 0.15 12.1 16.8 1.1 9.2 6.1 3.7 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Csm1_N PF18504.1 KXX80767.1 - 0.2 12.0 3.8 21 5.5 0.1 3.7 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF724 PF05266.14 KXX80767.1 - 0.81 9.5 9.5 6.8 6.5 0.2 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF724) V-SNARE PF05008.15 KXX80767.1 - 1.1 9.7 6.1 2 8.8 0.2 3.5 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DegS PF05384.11 KXX80767.1 - 1.5 8.3 8.4 0.15 11.5 0.9 2.8 3 0 0 3 3 3 0 Sensor protein DegS Fmp27_WPPW PF10359.9 KXX80767.1 - 1.7 7.4 7.5 3.6 6.3 5.2 2.4 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain TMF_DNA_bd PF12329.8 KXX80767.1 - 3.1 7.8 14.9 2.6 8.1 0.0 4.6 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding LPP PF04728.13 KXX80767.1 - 3.5 8.1 10.4 26 5.3 0.2 4.1 4 1 1 5 5 5 0 Lipoprotein leucine-zipper COG2 PF06148.11 KXX80767.1 - 4.1 7.5 12.8 13 5.9 1.2 4.1 3 1 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 KXX80767.1 - 4.6 7.3 20.0 5.8 7.0 3.6 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 KXX80767.1 - 5.8 7.6 5.5 83 3.9 0.0 3.6 3 2 1 4 4 4 0 Initiation control protein YabA CENP-H PF05837.12 KXX80767.1 - 6.2 7.3 16.6 2.3 8.7 0.5 4.0 3 2 1 4 4 4 0 Centromere protein H (CENP-H) Sin_N PF04801.13 KXX80769.1 - 8.9e-23 81.2 0.0 2.2e-22 79.9 0.0 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region FlgM PF04316.13 KXX80769.1 - 0.026 14.9 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM SNO PF01174.19 KXX80770.1 - 7.2e-53 179.2 0.0 1.3e-41 142.6 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXX80770.1 - 2.4e-10 40.3 0.1 9.5e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KXX80770.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 KXX80770.1 - 0.0033 17.3 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KXX80770.1 - 0.0039 17.0 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I SR-25 PF10500.9 KXX80770.1 - 1.8 8.1 8.2 2.7 7.5 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KXX80770.1 - 5.2 7.8 8.6 0.22 12.2 2.9 1.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein She9_MDM33 PF05546.11 KXX80771.1 - 2.4e-80 269.0 3.4 3.1e-80 268.7 3.4 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Tropomyosin_1 PF12718.7 KXX80771.1 - 0.0069 16.6 0.2 0.017 15.3 0.2 1.6 1 0 0 1 1 1 1 Tropomyosin like BCAS2 PF05700.11 KXX80771.1 - 0.011 15.5 1.2 0.013 15.2 0.2 1.8 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) TPR_21 PF09976.9 KXX80771.1 - 0.019 14.7 0.3 0.019 14.7 0.3 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain SOG2 PF10428.9 KXX80771.1 - 0.055 12.7 17.1 0.084 12.1 17.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KXX80771.1 - 0.13 11.0 8.9 0.18 10.4 8.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Serine_rich PF08824.10 KXX80771.1 - 0.16 12.0 1.4 2.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain ADIP PF11559.8 KXX80771.1 - 0.75 9.9 5.3 0.21 11.6 2.1 1.7 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding PsbH PF00737.20 KXX80771.1 - 1.1 9.0 4.3 0.42 10.4 1.1 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein SfLAP PF11139.8 KXX80771.1 - 1.2 8.5 4.3 3 7.2 4.3 1.6 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein PRCC PF10253.9 KXX80771.1 - 1.2 9.8 17.1 0.22 12.3 12.8 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting APG6_N PF17675.1 KXX80771.1 - 2.7 8.5 9.7 0.48 10.9 0.3 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 KXX80771.1 - 5 7.5 6.5 0.51 10.7 0.3 2.3 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 KXX80771.1 - 6.7 7.2 10.4 0.15 12.5 2.1 2.5 3 1 0 3 3 3 0 Cell division protein ZapB Pkinase PF00069.25 KXX80772.1 - 1.6e-59 201.4 0.0 3e-59 200.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80772.1 - 2e-35 122.3 0.0 3.8e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KXX80772.1 - 1.6e-21 76.2 26.9 1.6e-12 47.3 4.5 2.9 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 KXX80772.1 - 4.7e-21 74.4 26.5 1.4e-12 47.2 9.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KXX80772.1 - 2.1e-14 53.9 1.3 8.1e-14 52.1 1.3 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KXX80772.1 - 5.2e-05 23.5 0.0 9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KXX80772.1 - 0.04 13.2 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KXX80772.1 - 0.073 12.7 0.1 0.69 9.5 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAT1 PF09770.9 KXX80772.1 - 4.1 5.5 6.5 6.8 4.8 6.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HET PF06985.11 KXX80773.1 - 2e-27 96.4 0.0 3.5e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HATPase_c PF02518.26 KXX80774.1 - 0.00079 19.9 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_transf_15 PF01793.16 KXX80775.1 - 4.7e-132 440.2 9.8 5.4e-132 439.9 9.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.9 KXX80776.1 - 0 1231.9 15.7 8.8e-293 973.8 3.3 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Acyl-CoA_dh_1 PF00441.24 KXX80777.1 - 5.9e-37 127.2 3.6 1e-36 126.4 3.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXX80777.1 - 1.6e-28 99.6 0.5 4.2e-28 98.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXX80777.1 - 7.1e-23 80.6 0.0 1.5e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXX80777.1 - 1.2e-17 64.4 0.6 2.3e-17 63.5 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXX80777.1 - 0.0029 17.3 0.0 0.009 15.7 0.0 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 KXX80777.1 - 0.0063 16.5 0.2 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Staphylococcal AgrD protein Ribosom_S12_S23 PF00164.25 KXX80778.1 - 1.2e-28 99.1 0.7 1.5e-28 98.7 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Beta_elim_lyase PF01212.21 KXX80781.1 - 3.2e-55 187.5 0.0 4.8e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Trp_DMAT PF11991.8 KXX80781.1 - 5.4e-10 39.2 0.0 1.8e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase SK_channel PF03530.14 KXX80782.1 - 0.033 14.2 0.8 0.033 14.2 0.8 1.9 2 0 0 2 2 2 0 Calcium-activated SK potassium channel DUF1980 PF09323.10 KXX80782.1 - 0.73 9.7 2.5 3.8 7.4 0.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) p450 PF00067.22 KXX80783.1 - 1.7e-62 211.7 0.0 2.1e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KXX80784.1 - 1.2e-12 47.9 0.2 2.2e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX80784.1 - 0.11 13.5 0.0 0.18 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KXX80785.1 - 9e-21 74.4 0.0 1.8e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX80785.1 - 8.8e-09 36.0 0.0 5.6e-08 33.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX80785.1 - 2.5e-05 24.1 0.0 0.00098 18.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX80785.1 - 2.9e-05 24.6 0.0 6.8e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX80785.1 - 0.0002 22.1 0.0 0.0026 18.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXX80785.1 - 0.037 13.5 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KXX80785.1 - 0.061 12.9 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXX80785.1 - 0.096 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KXX80785.1 - 0.15 11.4 0.0 0.95 8.7 0.0 2.2 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase Spindle_Spc25 PF08234.12 KXX80786.1 - 1.4e-25 89.2 0.0 4.1e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Atg14 PF10186.9 KXX80786.1 - 0.015 14.4 5.8 0.018 14.2 5.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Hom_end_hint PF05203.16 KXX80786.1 - 0.36 10.7 2.7 0.53 10.2 2.7 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint DUF4407 PF14362.6 KXX80786.1 - 2.9 7.2 16.0 4.2 6.6 16.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KXX80786.1 - 8.4 5.5 10.8 12 5.0 10.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein MOZART1 PF12554.8 KXX80787.1 - 2.5e-25 88.0 0.8 3.1e-25 87.7 0.8 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zinc_ribbon_6 PF14599.6 KXX80788.1 - 6.7e-24 83.7 1.1 6.7e-24 83.7 1.1 3.7 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 KXX80788.1 - 8.4e-18 64.6 20.2 8.4e-18 64.6 20.2 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KXX80788.1 - 6.9e-09 35.9 9.7 6.9e-09 35.9 9.7 5.0 2 1 3 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX80788.1 - 1.4e-06 28.1 7.8 1.4e-06 28.1 7.8 4.7 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXX80788.1 - 0.00067 19.8 6.8 0.00067 19.8 6.8 5.1 4 1 2 6 6 6 1 zinc finger of C3HC4-type, RING DIRP PF06584.13 KXX80788.1 - 0.21 11.8 0.3 0.83 9.9 0.0 1.9 2 0 0 2 2 2 0 DIRP SDA1 PF05285.12 KXX80788.1 - 8.6 5.7 16.9 13 5.1 16.9 1.2 1 0 0 1 1 1 0 SDA1 Exo_endo_phos PF03372.23 KXX80789.1 - 2.6e-08 33.7 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L3 PF00297.22 KXX80790.1 - 1.5e-11 43.9 3.5 1.3e-08 34.2 3.5 2.3 1 1 0 1 1 1 1 Ribosomal protein L3 NifQ PF04891.12 KXX80790.1 - 0.012 15.9 1.2 0.021 15.2 1.2 1.3 1 0 0 1 1 1 0 NifQ TMF_DNA_bd PF12329.8 KXX80790.1 - 0.027 14.5 3.0 0.044 13.8 3.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding LTXXQ PF07813.12 KXX80790.1 - 0.036 14.8 2.0 0.078 13.7 2.0 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein NFACT-R_1 PF05670.13 KXX80791.1 - 2.9e-38 130.8 0.0 4.6e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain PITH PF06201.13 KXX80792.1 - 4.3e-44 150.4 0.0 5.2e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.9 KXX80793.1 - 2.4e-107 360.5 0.0 8.8e-107 358.7 0.0 1.9 2 1 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor CPSase_L_D2 PF02786.17 KXX80794.1 - 5e-81 271.2 0.3 7.9e-81 270.6 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KXX80794.1 - 1.2e-69 234.0 0.0 2.5e-69 233.0 0.0 1.6 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KXX80794.1 - 6e-35 120.1 0.1 1.2e-34 119.2 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXX80794.1 - 9.3e-32 109.3 0.0 2.3e-31 108.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KXX80794.1 - 4.2e-26 92.1 0.0 8.2e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KXX80794.1 - 5.9e-19 67.7 0.8 1.9e-18 66.0 0.4 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXX80794.1 - 1.5e-09 37.5 0.2 7.1e-06 25.8 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KXX80794.1 - 1.6e-09 37.6 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXX80794.1 - 4.5e-08 32.9 0.1 8.7e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KXX80794.1 - 3.3e-05 23.2 0.0 0.09 12.0 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KXX80794.1 - 4.4e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KXX80794.1 - 0.0029 17.2 0.0 0.016 14.8 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KXX80794.1 - 0.0093 15.6 0.1 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KXX80794.1 - 0.011 15.5 0.0 0.041 13.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KXX80794.1 - 0.012 14.9 0.0 0.052 12.8 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KXX80794.1 - 0.012 15.5 0.1 0.1 12.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.6 KXX80794.1 - 0.056 14.2 0.1 16 6.3 0.0 3.0 2 0 0 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 KXX80794.1 - 0.092 12.6 0.2 0.72 9.8 0.1 2.4 1 1 1 2 2 2 0 Glycine cleavage H-protein p450 PF00067.22 KXX80795.1 - 1.5e-54 185.5 0.0 2e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L5_C PF00673.21 KXX80796.1 - 7.7e-22 77.3 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXX80796.1 - 2.6e-20 72.5 0.0 7.3e-20 71.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 ApbA PF02558.16 KXX80796.1 - 0.14 11.8 0.0 0.8 9.3 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pkinase PF00069.25 KXX80797.1 - 3.7e-28 98.6 0.0 6.6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.11 KXX80797.1 - 7.2e-24 84.8 0.0 1.3e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 KXX80797.1 - 4.2e-15 55.7 0.0 6.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Coa1 PF08695.10 KXX80800.1 - 2.2e-40 137.0 0.0 2.9e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SLATT_1 PF18181.1 KXX80801.1 - 0.059 13.3 1.3 0.85 9.6 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DNA_pol_phi PF04931.13 KXX80802.1 - 1.9e-185 618.2 6.6 2.9e-185 617.6 6.6 1.3 1 0 0 1 1 1 1 DNA polymerase phi DUF1676 PF07898.13 KXX80802.1 - 0.13 12.3 2.1 0.3 11.1 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Vps35 PF03635.17 KXX80802.1 - 0.5 8.8 3.2 2.1 6.8 1.2 2.3 2 1 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 Proteasome PF00227.26 KXX80803.1 - 1.3e-47 161.7 2.7 1.7e-31 109.2 0.0 3.1 3 0 0 3 3 3 3 Proteasome subunit Proteasome_A_N PF10584.9 KXX80803.1 - 1.4e-11 43.8 1.2 1.5e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ecl1 PF12855.7 KXX80804.1 - 4.4e-13 50.8 20.7 4.5e-12 47.5 20.7 1.9 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KXX80804.1 - 0.18 11.9 3.4 0.41 10.8 3.4 1.6 1 0 0 1 1 1 0 MYND finger zf-DNL PF05180.12 KXX80805.1 - 1.6e-27 95.2 0.1 2.4e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger JHY PF15261.6 KXX80805.1 - 0.0093 16.7 0.2 0.013 16.3 0.2 1.3 1 0 0 1 1 1 1 Jhy protein zf-CSL PF05207.13 KXX80805.1 - 0.023 14.4 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 CSL zinc finger Msg2_C PF12373.8 KXX80805.1 - 0.026 14.0 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Elf1 PF05129.13 KXX80805.1 - 0.064 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KXX80805.1 - 0.099 12.8 0.5 0.21 11.8 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF4379 PF14311.6 KXX80805.1 - 0.14 12.5 0.5 0.27 11.6 0.5 1.5 1 0 0 1 1 1 0 Probable Zinc-ribbon domain DUF3408 PF11888.8 KXX80805.1 - 1.8 8.7 4.3 0.75 9.9 1.2 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3408) DRIM PF07539.12 KXX80806.1 - 6.4e-207 688.7 1.7 6.4e-207 688.7 1.7 2.4 2 1 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.22 KXX80806.1 - 8.2e-05 22.5 10.8 9.5 6.8 0.0 8.7 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KXX80806.1 - 0.0036 17.9 1.6 0.62 10.7 0.0 4.2 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region TFCD_C PF12612.8 KXX80806.1 - 0.025 14.4 0.2 5.9 6.7 0.0 3.9 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal Dopey_N PF04118.14 KXX80806.1 - 0.086 11.9 0.9 12 4.9 0.1 4.2 4 1 0 4 4 4 0 Dopey, N-terminal DUF3161 PF11362.8 KXX80806.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) CwfJ_C_1 PF04677.15 KXX80807.1 - 2.1e-24 85.7 0.0 5.2e-24 84.5 0.0 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KXX80807.1 - 7.4e-15 55.6 1.7 1.9e-14 54.3 1.7 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Rhodanese PF00581.20 KXX80808.1 - 1.2e-12 48.3 0.1 2.5e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Cullin PF00888.22 KXX80810.1 - 3.8e-179 597.3 3.2 7e-179 596.4 3.2 1.4 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXX80810.1 - 3.2e-26 91.2 0.4 3.2e-26 91.2 0.4 2.2 3 0 0 3 3 3 1 Cullin protein neddylation domain LSM PF01423.22 KXX80811.1 - 7e-19 67.3 0.0 9.1e-19 66.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain Glyco_transf_4 PF13439.6 KXX80812.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Pkinase PF00069.25 KXX80813.1 - 1.1e-11 44.7 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80813.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXX80813.1 - 0.13 11.2 0.1 0.37 9.7 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase MMR_HSR1 PF01926.23 KXX80814.1 - 0.038 14.1 1.1 0.084 13.0 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AIG1 PF04548.16 KXX80814.1 - 0.041 13.2 0.4 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 KXX80814.1 - 0.053 13.6 0.0 0.053 13.6 0.0 2.8 2 1 0 2 2 2 0 Dynamin family DUF4047 PF13256.6 KXX80814.1 - 0.21 11.8 7.6 0.26 11.5 6.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) 60KD_IMP PF02096.20 KXX80814.1 - 7.4 6.4 5.6 5 7.0 0.2 2.3 1 1 1 2 2 2 0 60Kd inner membrane protein MMR_HSR1 PF01926.23 KXX80815.1 - 2.9e-05 24.1 0.0 7.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX80815.1 - 9.5e-05 22.4 0.1 0.00019 21.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 KXX80815.1 - 0.035 13.4 0.1 0.087 12.1 0.0 1.8 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 KXX80815.1 - 0.059 13.6 0.6 0.25 11.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KXX80815.1 - 0.076 13.6 1.6 0.43 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain KapB PF08810.10 KXX80815.1 - 0.097 12.8 0.8 0.29 11.3 0.8 1.7 1 0 0 1 1 1 0 Kinase associated protein B Dynamin_N PF00350.23 KXX80815.1 - 0.42 10.6 0.0 0.42 10.6 0.0 3.5 2 2 1 3 3 3 0 Dynamin family DUF87 PF01935.17 KXX80815.1 - 0.75 9.8 0.0 0.75 9.8 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 KXX80815.1 - 0.95 10.0 0.0 0.95 10.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Peptidase_C37 PF05416.12 KXX80815.1 - 2.2 6.7 12.6 0.02 13.4 4.8 1.4 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Methyltr_RsmB-F PF01189.17 KXX80816.1 - 1e-76 257.0 0.0 1.8e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KXX80816.1 - 4.9e-08 33.3 0.0 1.5e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF DUF2431 PF10354.9 KXX80816.1 - 0.0097 16.2 0.0 0.03 14.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Clathrin PF00637.20 KXX80817.1 - 9e-198 648.1 42.3 1.7e-32 112.2 1.0 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KXX80817.1 - 1.1e-34 118.2 0.3 5.6e-34 115.9 0.3 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 KXX80817.1 - 5.8e-34 114.8 0.6 6.5e-08 32.5 0.1 6.5 6 0 0 6 6 6 5 Clathrin propeller repeat TPR_14 PF13428.6 KXX80817.1 - 9.6e-05 22.9 13.7 1.8 9.6 0.1 8.7 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX80817.1 - 0.0022 17.9 9.0 5.1 7.4 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat Clathrin-link PF09268.10 KXX80817.1 - 0.0037 16.6 0.7 3.5 7.1 0.0 2.9 2 0 0 2 2 2 2 Clathrin, heavy-chain linker TPR_8 PF13181.6 KXX80817.1 - 0.023 14.9 4.1 5.8 7.4 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 KXX80817.1 - 0.093 13.0 0.5 48 4.5 0.0 4.8 3 0 0 3 3 3 0 PPR repeat Ank_5 PF13857.6 KXX80817.1 - 0.11 12.8 0.0 37 4.8 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) TPR_1 PF00515.28 KXX80817.1 - 0.22 11.4 2.5 1.3e+02 2.7 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1640 PF07798.11 KXX80818.1 - 1.6e-56 191.1 9.4 2e-56 190.8 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 KXX80818.1 - 0.03 13.7 1.5 0.071 12.5 0.1 1.9 1 1 1 2 2 2 0 GNAT acetyltransferase 2 MPC PF03650.13 KXX80819.1 - 1.3e-34 118.6 0.0 1.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 KXX80819.1 - 0.08 13.0 0.2 0.12 12.4 0.2 1.4 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Cyto_heme_lyase PF01265.17 KXX80820.1 - 3.8e-125 417.3 0.5 4.7e-125 417.0 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Ribosomal_S28e PF01200.18 KXX80822.1 - 7.7e-31 105.9 2.2 8.5e-31 105.8 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ABC1 PF03109.16 KXX80823.1 - 5.1e-24 84.7 0.0 2.5e-14 53.5 0.0 2.4 1 1 1 2 2 2 2 ABC1 family APH PF01636.23 KXX80823.1 - 0.06 13.3 0.9 0.16 11.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cu-oxidase_2 PF07731.14 KXX80824.1 - 3.4e-39 133.7 6.6 5.5e-39 133.0 0.1 3.3 3 2 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KXX80824.1 - 1.8e-35 122.4 0.0 2.4e-34 118.7 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXX80824.1 - 3e-33 114.3 6.4 2.2e-32 111.6 1.6 3.5 4 0 0 4 4 4 1 Multicopper oxidase GCIP PF13324.6 KXX80825.1 - 8.8e-22 78.0 0.1 3.7e-21 75.9 0.0 2.0 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting RNA_pol_3_Rpc31 PF11705.8 KXX80825.1 - 0.0063 16.8 6.6 0.0091 16.3 6.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Utp14 PF04615.13 KXX80825.1 - 0.031 12.9 5.0 0.042 12.4 5.0 1.1 1 0 0 1 1 1 0 Utp14 protein CNDH2_C PF16858.5 KXX80825.1 - 0.062 13.2 0.2 0.081 12.8 0.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 KXX80825.1 - 0.28 9.4 2.3 0.39 8.9 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 KXX80825.1 - 0.52 10.1 2.3 17 5.2 1.7 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRN3 PF05327.11 KXX80825.1 - 0.69 8.4 6.2 1.2 7.6 5.6 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 TT_ORF2 PF02957.15 KXX80825.1 - 0.84 10.6 6.0 2.2 9.2 6.0 1.7 1 0 0 1 1 1 0 TT viral ORF2 DUF4611 PF15387.6 KXX80825.1 - 3.3 8.0 8.0 8.9 6.6 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KXX80825.1 - 4.4 6.5 10.1 6.2 6.1 10.1 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KXX80825.1 - 5.5 6.6 11.1 19 4.9 11.7 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DbpA PF03880.15 KXX80826.1 - 0.068 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Questin_oxidase PF14027.6 KXX80827.1 - 0.03 13.9 0.1 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 Questin oxidase-like gpW PF02831.15 KXX80827.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 gpW DASH_Duo1 PF08651.10 KXX80827.1 - 0.12 12.2 0.8 0.68 9.8 0.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 PRKCSH-like PF12999.7 KXX80828.1 - 9.3e-40 136.3 3.7 1.5e-23 83.5 0.1 3.0 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KXX80828.1 - 1.4e-31 109.2 0.5 1.4e-31 109.2 0.5 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KXX80828.1 - 1.7e-10 41.7 0.9 4.2e-10 40.5 0.9 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KXX80828.1 - 0.00044 20.2 0.4 0.00044 20.2 0.4 1.8 2 0 0 2 2 2 1 Autophagy-related protein 27 DUF773 PF05600.12 KXX80828.1 - 0.0039 16.0 1.6 0.0039 16.0 1.6 1.4 1 1 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 NPV_P10 PF05531.12 KXX80828.1 - 0.021 15.3 2.1 0.049 14.1 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 KXX80828.1 - 0.022 14.3 19.4 0.043 13.4 9.0 2.7 3 0 0 3 3 3 0 Intermediate filament protein Myb_DNA-bind_4 PF13837.6 KXX80828.1 - 0.024 15.0 1.1 0.12 12.7 0.3 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3086 PF11285.8 KXX80828.1 - 0.033 13.3 1.4 0.081 12.0 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Mod_r PF07200.13 KXX80828.1 - 0.052 13.7 0.6 0.052 13.7 0.6 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein PspB PF06667.12 KXX80828.1 - 0.15 12.2 0.3 0.15 12.2 0.3 1.9 2 0 0 2 2 1 0 Phage shock protein B DUF4200 PF13863.6 KXX80828.1 - 0.26 11.7 20.7 1.5 9.2 8.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KXX80828.1 - 0.42 10.7 18.7 4.3 7.4 0.2 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ABATE PF07336.11 KXX80828.1 - 0.45 11.2 4.2 30 5.3 1.6 2.9 2 1 0 2 2 2 0 Putative stress-induced transcription regulator Prefoldin_2 PF01920.20 KXX80828.1 - 0.74 9.8 18.1 9 6.3 0.1 4.2 3 1 1 4 4 4 0 Prefoldin subunit PspA_IM30 PF04012.12 KXX80828.1 - 3.2 7.2 17.7 0.93 9.0 7.1 2.6 3 0 0 3 3 3 0 PspA/IM30 family FlaC_arch PF05377.11 KXX80828.1 - 3.5 8.1 6.6 28 5.2 2.5 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KXX80828.1 - 3.8 7.9 8.2 3.1 8.2 1.2 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ldl_recept_a PF00057.18 KXX80828.1 - 5.3 7.3 12.0 1.2 9.5 1.8 3.1 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A Spc7 PF08317.11 KXX80828.1 - 8.2 5.2 17.1 8.9 5.1 0.3 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein Spc24 PF08286.11 KXX80828.1 - 8.4 6.7 12.3 17 5.7 2.7 3.5 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 Rtf2 PF04641.12 KXX80829.1 - 6.9e-48 163.3 0.0 9.5e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KXX80829.1 - 0.00013 21.9 0.1 0.00019 21.3 0.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXX80829.1 - 0.00052 19.8 0.2 0.00085 19.1 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX80829.1 - 0.00089 19.2 0.0 0.0027 17.7 0.0 1.8 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXX80829.1 - 0.0048 16.7 0.3 0.013 15.4 0.4 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXX80829.1 - 0.0049 17.2 0.1 0.0084 16.4 0.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KXX80829.1 - 0.16 11.8 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 KXX80829.1 - 0.19 11.8 0.7 0.45 10.7 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain MFS_1 PF07690.16 KXX80830.1 - 1.5e-24 86.6 34.0 1.5e-24 86.6 34.0 2.2 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX80830.1 - 2.7e-12 46.3 8.3 2.7e-12 46.3 8.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXX80830.1 - 1.4e-07 30.3 2.0 1.4e-07 30.3 2.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UQ_con PF00179.26 KXX80831.1 - 5.6e-20 71.4 0.1 8.1e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX80831.1 - 0.092 12.4 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family B Tyr_Deacylase PF02580.16 KXX80832.1 - 1.7e-52 177.7 0.1 2e-52 177.5 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FAT PF02259.23 KXX80833.1 - 1e-135 452.5 4.1 1e-135 452.5 4.1 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXX80833.1 - 1e-73 248.2 0.1 1.8e-73 247.4 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KXX80833.1 - 3.4e-69 231.9 9.3 3.1e-65 219.0 0.1 6.1 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KXX80833.1 - 1.3e-44 150.7 3.1 1.4e-44 150.5 0.1 2.8 3 0 0 3 3 1 1 FKBP12-rapamycin binding domain HEAT PF02985.22 KXX80833.1 - 2e-19 68.0 12.3 0.0012 18.9 0.0 10.9 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 KXX80833.1 - 2e-14 53.7 7.4 0.0013 19.0 0.1 7.5 6 0 0 6 6 6 3 HEAT repeats FATC PF02260.20 KXX80833.1 - 1.7e-13 50.1 0.2 6.3e-13 48.3 0.2 2.1 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 KXX80833.1 - 8.5e-11 42.2 4.9 0.0089 16.1 0.0 6.7 4 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXX80833.1 - 1e-08 35.5 13.3 0.14 12.7 0.0 10.9 9 3 3 12 12 10 2 HEAT-like repeat Adaptin_N PF01602.20 KXX80833.1 - 1.7e-07 30.2 6.3 0.0013 17.4 0.2 4.2 3 1 1 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 KXX80833.1 - 0.00031 20.4 5.3 3.9 7.0 0.0 5.7 5 1 1 6 6 6 2 CLASP N terminal RIX1 PF08167.12 KXX80833.1 - 0.0023 17.7 0.3 4.2 7.1 0.0 4.6 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis UME PF08064.13 KXX80833.1 - 0.0046 16.9 4.6 5.4 7.0 0.0 6.6 7 0 0 7 7 7 1 UME (NUC010) domain FANCI_S2 PF14676.6 KXX80833.1 - 0.008 16.5 0.5 2.1 8.6 0.1 4.1 4 0 0 4 4 4 1 FANCI solenoid 2 DUF3730 PF12530.8 KXX80833.1 - 0.027 14.0 4.2 4.4 6.8 0.1 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3730) ANAPC3 PF12895.7 KXX80833.1 - 1 9.6 4.3 28 5.0 0.0 4.2 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec7_N PF12783.7 KXX80833.1 - 6.3 6.7 8.5 31 4.4 0.0 4.8 5 1 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ADH_zinc_N PF00107.26 KXX80835.1 - 1.6e-18 66.9 0.0 2.9e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX80835.1 - 1.7e-13 51.7 0.0 4.6e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX80835.1 - 8e-08 32.1 0.0 5.1e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 4HBT PF03061.22 KXX80837.1 - 5.1e-06 26.8 0.0 6.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KXX80837.1 - 5.7e-06 26.8 0.0 8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KXX80837.1 - 8.7e-05 21.9 3.1 0.00018 20.9 2.6 1.6 1 1 0 2 2 2 1 Acyl-ACP thioesterase YqzH PF14164.6 KXX80837.1 - 0.05 13.7 0.3 0.097 12.8 0.3 1.4 1 0 0 1 1 1 0 YqzH-like protein Leu_zip PF15294.6 KXX80839.1 - 0.012 15.1 1.2 0.017 14.7 1.2 1.1 1 0 0 1 1 1 0 Leucine zipper Csm1_N PF18504.1 KXX80839.1 - 0.018 15.3 5.2 0.028 14.7 5.2 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KXX80839.1 - 0.055 13.6 13.8 0.075 13.1 13.1 1.5 1 1 1 2 2 2 0 bZIP transcription factor Guanylate_kin PF00625.21 KXX80839.1 - 0.31 10.7 1.2 0.41 10.3 1.2 1.1 1 0 0 1 1 1 0 Guanylate kinase PseudoU_synth_2 PF00849.22 KXX80840.1 - 3e-28 98.9 0.0 4.7e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KXX80840.1 - 0.0039 16.9 0.0 0.0097 15.6 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.6 KXX80840.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin Auto_anti-p27 PF06677.12 KXX80840.1 - 0.089 13.0 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF5125 PF17163.4 KXX80841.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5125) UCR_Fe-S_N PF10399.9 KXX80841.1 - 0.73 9.2 7.9 2 7.8 7.9 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MFS_1 PF07690.16 KXX80842.1 - 7e-26 91.0 40.1 1.9e-21 76.4 10.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX80842.1 - 8.4e-08 31.5 1.2 8.4e-08 31.5 1.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Ctr PF04145.15 KXX80842.1 - 0.066 13.8 0.0 11 6.7 0.0 2.5 2 0 0 2 2 2 0 Ctr copper transporter family DUF2723 PF11028.8 KXX80842.1 - 0.45 10.4 5.1 0.27 11.1 0.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2723) S1_2 PF13509.6 KXX80843.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 S1 domain U1snRNP70_N PF12220.8 KXX80843.1 - 4 8.2 9.9 45 4.8 0.1 2.8 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-C3HC4_3 PF13920.6 KXX80843.1 - 7.7 6.5 8.6 2.1 8.3 3.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ABC2_membrane PF01061.24 KXX80844.1 - 7.5e-78 260.8 49.6 1.1e-51 175.2 23.2 4.7 4 1 1 5 5 5 3 ABC-2 type transporter PDR_CDR PF06422.12 KXX80844.1 - 2e-36 123.8 10.5 4.2e-32 109.9 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KXX80844.1 - 3.1e-34 118.4 0.0 8.6e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KXX80844.1 - 6.2e-17 62.0 0.1 1.6e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXX80844.1 - 1.7e-06 28.5 0.4 0.001 19.5 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXX80844.1 - 6.3e-06 26.2 0.1 0.00037 20.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KXX80844.1 - 3.7e-05 23.4 0.0 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXX80844.1 - 0.00022 20.9 0.5 0.034 13.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXX80844.1 - 0.00023 21.1 0.0 0.73 9.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KXX80844.1 - 0.00027 21.1 0.0 0.12 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXX80844.1 - 0.00028 21.4 0.0 0.03 14.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KXX80844.1 - 0.002 18.4 0.1 0.46 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXX80844.1 - 0.0038 17.7 0.0 2 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXX80844.1 - 0.007 15.8 0.0 1.7 8.0 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 KXX80844.1 - 0.012 15.2 0.4 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HalX PF08663.10 KXX80844.1 - 0.019 15.3 0.0 5.8 7.3 0.0 2.4 2 0 0 2 2 2 0 HalX domain NACHT PF05729.12 KXX80844.1 - 0.022 14.7 0.2 3.2 7.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KXX80844.1 - 0.044 13.5 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXX80844.1 - 0.081 13.4 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX80844.1 - 0.11 12.2 1.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 AAA domain Voltage_CLC PF00654.20 KXX80844.1 - 0.4 9.9 11.6 2.1 7.5 0.3 2.9 3 0 0 3 3 3 0 Voltage gated chloride channel ABC2_membrane_3 PF12698.7 KXX80844.1 - 2.8 7.0 33.3 0.0056 15.8 11.6 3.1 3 1 1 4 4 4 0 ABC-2 family transporter protein Bac_surface_Ag PF01103.23 KXX80845.1 - 2.7e-42 145.4 0.5 3.5e-42 145.1 0.5 1.1 1 0 0 1 1 1 1 Surface antigen Sugar_tr PF00083.24 KXX80846.1 - 1.8e-85 287.5 15.4 2e-85 287.3 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX80846.1 - 2e-21 76.3 37.2 2.2e-20 72.9 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXX80846.1 - 0.051 11.9 0.7 0.17 10.1 0.7 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_4 PF01565.23 KXX80847.1 - 1.9e-24 86.0 1.2 3.6e-24 85.1 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX80847.1 - 3.8e-13 49.3 0.1 9.7e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like COesterase PF00135.28 KXX80848.1 - 6.3e-76 256.3 0.0 8.8e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX80848.1 - 2.1e-08 34.3 0.3 1.4e-07 31.6 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX80848.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family CDH-cyt PF16010.5 KXX80849.1 - 6.7e-49 166.0 0.1 7.7e-49 165.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase RhgB_N PF09284.10 KXX80850.1 - 2.2e-107 358.3 2.6 3.2e-107 357.8 2.6 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KXX80850.1 - 1.1e-43 148.9 0.0 2.6e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXX80850.1 - 1.6e-22 79.0 4.6 1.6e-22 79.0 4.6 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXX80850.1 - 1.3e-05 25.4 1.5 1.3e-05 25.4 1.5 3.0 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KXX80850.1 - 0.042 13.9 0.6 0.15 12.0 0.6 2.0 1 0 0 1 1 1 0 CarboxypepD_reg-like domain DUF1735 PF08522.10 KXX80850.1 - 0.045 14.3 1.5 13 6.4 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF1735) DUF2012 PF09430.10 KXX80850.1 - 0.093 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Peptidase_M28 PF04389.17 KXX80851.1 - 8.9e-35 120.2 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXX80851.1 - 4.1e-09 36.4 1.0 1.4e-08 34.7 1.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KXX80851.1 - 0.013 15.0 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Nicastrin Aldo_ket_red PF00248.21 KXX80852.1 - 1.6e-46 158.8 0.0 2.3e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Transposase_20 PF02371.16 KXX80852.1 - 0.14 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family RasGAP PF00616.19 KXX80853.1 - 3.4e-31 108.6 0.0 3.2e-22 79.3 0.0 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KXX80853.1 - 0.00016 21.9 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain SNF2_N PF00176.23 KXX80855.1 - 4.9e-13 48.5 0.0 1.4e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 KXX80855.1 - 3.9e-08 33.0 0.0 8.6e-07 28.6 0.0 2.7 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.6 KXX80855.1 - 0.00018 21.4 6.4 0.00018 21.4 6.4 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Helicase_C PF00271.31 KXX80855.1 - 0.0029 17.9 0.1 0.0067 16.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KXX80855.1 - 0.032 14.1 5.2 0.09 12.7 5.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GFA PF04828.14 KXX80855.1 - 0.033 14.5 0.3 0.033 14.5 0.3 2.6 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ureidogly_lyase PF04115.12 KXX80856.1 - 1.3e-59 201.2 0.0 2e-59 200.5 0.0 1.3 1 1 0 1 1 1 1 Ureidoglycolate lyase Mucin PF01456.17 KXX80856.1 - 0.096 12.7 18.9 0.16 12.0 18.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 KXX80856.1 - 0.22 9.4 3.9 0.26 9.2 3.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 KXX80856.1 - 1.7 6.7 5.1 2.1 6.4 5.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3439 PF11921.8 KXX80856.1 - 4 7.4 18.8 7.3 6.6 18.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2 PF00096.26 KXX80857.1 - 0.063 13.8 17.7 0.36 11.4 0.2 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Not3 PF04065.15 KXX80858.1 - 6.4e-90 300.6 25.0 6.4e-90 300.6 25.0 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KXX80858.1 - 1.8e-42 144.5 9.4 4.3e-42 143.3 9.4 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KXX80858.1 - 0.0049 17.2 4.7 0.0049 17.2 4.7 2.5 3 0 0 3 3 2 1 Syntaxin-like protein ABC_tran_CTD PF16326.5 KXX80858.1 - 0.007 16.6 6.8 0.007 16.6 6.8 3.4 2 1 0 2 2 1 1 ABC transporter C-terminal domain Snapin_Pallidin PF14712.6 KXX80858.1 - 0.0072 16.7 0.5 0.0072 16.7 0.5 2.8 2 1 1 3 3 3 1 Snapin/Pallidin DUF2373 PF10180.9 KXX80858.1 - 0.014 15.3 2.8 0.032 14.1 2.8 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) HR1 PF02185.16 KXX80858.1 - 0.028 14.5 1.8 0.028 14.5 1.8 3.0 3 0 0 3 3 3 0 Hr1 repeat Cep57_MT_bd PF06657.13 KXX80858.1 - 0.042 14.3 13.1 0.38 11.2 2.6 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.11 KXX80858.1 - 0.069 13.2 7.5 0.079 13.0 3.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Sec5 PF15469.6 KXX80858.1 - 0.3 10.9 10.5 0.17 11.7 1.6 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 4HB_MCP_1 PF12729.7 KXX80858.1 - 2 7.9 15.3 0.64 9.5 9.1 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction CorA PF01544.18 KXX80858.1 - 6.9 5.9 9.0 0.76 9.0 1.9 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Pro_isomerase PF00160.21 KXX80859.1 - 5.8e-49 166.4 0.1 8.5e-49 165.9 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KXX80859.1 - 1.6e-06 27.7 3.0 0.00034 20.5 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX80859.1 - 0.00019 21.1 0.9 0.00058 19.6 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX80859.1 - 0.0018 18.4 0.1 0.0056 16.8 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX80859.1 - 0.002 18.4 0.4 0.0067 16.7 0.2 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXX80859.1 - 0.0045 17.1 1.0 0.011 15.9 1.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXX80859.1 - 0.0081 15.8 1.6 2.6 7.8 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 KXX80859.1 - 0.015 15.9 1.7 0.015 15.9 1.7 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX80859.1 - 0.036 14.7 1.3 0.11 13.1 0.2 2.6 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX80859.1 - 0.044 14.6 3.8 0.1 13.4 1.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXX80859.1 - 0.075 13.6 3.4 0.12 12.9 2.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KXX80859.1 - 0.095 12.6 0.3 0.15 11.9 0.3 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Iso_dh PF00180.20 KXX80860.1 - 3.3e-70 236.9 0.0 4e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short_C2 PF13561.6 KXX80861.1 - 2.4e-49 168.0 0.1 3.4e-49 167.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX80861.1 - 6e-38 130.3 0.1 8.7e-38 129.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX80861.1 - 5.9e-12 45.9 0.2 8.8e-12 45.3 0.2 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXX80861.1 - 0.11 11.8 0.3 0.32 10.4 0.3 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase PHD PF00628.29 KXX80865.1 - 2.6e-09 36.8 2.0 2.6e-09 36.8 2.0 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KXX80865.1 - 0.014 14.9 2.7 0.023 14.2 2.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 KXX80865.1 - 0.29 11.2 2.1 0.68 10.0 2.1 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger CEBP_ZZ PF16366.5 KXX80865.1 - 0.64 10.3 3.4 1.6 9.0 3.4 1.7 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain MMR_HSR1 PF01926.23 KXX80866.1 - 2.6e-11 43.6 0.0 4.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXX80866.1 - 0.0068 16.5 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin family IIGP PF05049.13 KXX80866.1 - 0.02 14.0 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 KXX80866.1 - 0.029 13.9 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXX80866.1 - 0.087 12.7 0.0 0.37 10.7 0.1 1.9 2 1 0 2 2 2 0 RsgA GTPase Aminotran_4 PF01063.19 KXX80866.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 1 0 1 1 1 0 Amino-transferase class IV Adeno_PIX PF03955.14 KXX80866.1 - 1.3 9.2 7.1 3 8.1 7.1 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) CDC45 PF02724.14 KXX80868.1 - 0.59 8.4 4.7 0.67 8.2 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein PRP38 PF03371.15 KXX80869.1 - 1.1e-57 194.7 0.0 1.3e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KXX80869.1 - 1.7e-05 25.3 22.2 1.7e-05 25.3 22.2 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PI3K_1B_p101 PF10486.9 KXX80869.1 - 0.061 11.1 0.3 0.073 10.8 0.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 KXX80869.1 - 2.4 6.3 5.4 2.9 6.1 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KXX80869.1 - 5.9 4.9 5.4 8.2 4.4 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Corona_nucleoca PF00937.18 KXX80869.1 - 8.1 5.4 9.8 12 4.8 9.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AAA PF00004.29 KXX80870.1 - 1.6e-30 106.2 0.0 6.7e-16 58.9 0.0 3.8 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KXX80870.1 - 2.3e-10 40.5 7.1 7.1e-10 38.9 2.5 3.8 4 0 0 4 4 4 1 AAA lid domain RuvB_N PF05496.12 KXX80870.1 - 6.4e-09 35.8 0.0 0.18 11.5 0.0 3.6 3 0 0 3 3 3 3 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXX80870.1 - 1.7e-08 34.5 0.1 0.0042 17.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXX80870.1 - 4.5e-08 33.1 0.0 0.054 13.2 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_22 PF13401.6 KXX80870.1 - 6.5e-07 29.7 1.4 0.12 12.7 0.2 5.0 3 2 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KXX80870.1 - 7.3e-07 28.8 0.0 0.13 11.7 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXX80870.1 - 1.6e-06 28.6 0.2 0.17 12.3 0.0 4.5 3 1 0 4 4 4 1 AAA ATPase domain Torsin PF06309.11 KXX80870.1 - 2.3e-06 27.7 0.0 0.41 10.7 0.0 3.3 3 0 0 3 3 3 1 Torsin IstB_IS21 PF01695.17 KXX80870.1 - 5.9e-06 26.1 0.2 0.073 12.8 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_19 PF13245.6 KXX80870.1 - 2.1e-05 24.9 0.1 0.78 10.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KXX80870.1 - 0.00017 21.7 0.0 0.18 12.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXX80870.1 - 0.00026 21.4 0.0 0.36 11.2 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 KXX80870.1 - 0.0011 18.7 0.5 0.54 9.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KXX80870.1 - 0.0011 19.5 2.7 0.6 10.7 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_7 PF12775.7 KXX80870.1 - 0.0084 15.6 0.2 1.6 8.2 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region MCM PF00493.23 KXX80870.1 - 0.03 13.4 0.0 6.8 5.7 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain Viral_helicase1 PF01443.18 KXX80870.1 - 0.034 13.9 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KXX80870.1 - 0.039 13.7 0.1 2 8.2 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain TniB PF05621.11 KXX80870.1 - 0.039 13.4 0.0 11 5.3 0.0 3.6 3 1 1 4 4 4 0 Bacterial TniB protein NTPase_1 PF03266.15 KXX80870.1 - 0.044 13.7 0.9 12 5.8 0.1 3.1 3 0 0 3 3 3 0 NTPase T2SSE PF00437.20 KXX80870.1 - 0.066 12.3 0.5 11 5.0 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_28 PF13521.6 KXX80870.1 - 0.066 13.5 4.5 2 8.6 0.1 3.6 4 0 0 4 4 3 0 AAA domain Pox_A32 PF04665.12 KXX80870.1 - 0.27 10.7 0.1 0.73 9.2 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_11 PF13086.6 KXX80870.1 - 0.65 9.7 0.0 0.65 9.7 0.0 5.4 4 1 0 4 4 3 0 AAA domain Borrelia_REV PF03978.13 KXX80871.1 - 0.16 11.9 2.0 0.89 9.5 0.3 2.8 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein Rsa3 PF14615.6 KXX80871.1 - 1.1 8.8 2.7 1.7 8.3 0.7 2.3 2 0 0 2 2 2 0 Ribosome-assembly protein 3 SlyX PF04102.12 KXX80871.1 - 2.2 9.0 34.4 0.26 11.9 2.1 6.7 6 0 0 6 6 6 0 SlyX DUF2935 PF11155.8 KXX80871.1 - 5.1 7.5 6.3 15 5.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) CorA PF01544.18 KXX80871.1 - 7.5 5.8 19.1 11 5.3 0.5 4.3 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein Val_tRNA-synt_C PF10458.9 KXX80871.1 - 7.6 6.9 7.3 0.62 10.4 0.5 2.7 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm RRM_1 PF00076.22 KXX80872.1 - 0.068 13.0 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 KXX80873.1 - 4.9e-52 175.8 0.0 5.6e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX80873.1 - 4.6e-21 75.3 0.0 6.2e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX80873.1 - 1.5e-05 24.5 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXX80873.1 - 0.026 14.1 0.0 0.078 12.5 0.0 1.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PQ-loop PF04193.14 KXX80874.1 - 1.7e-14 53.3 6.1 3.6e-13 49.1 0.6 2.8 2 1 1 3 3 3 2 PQ loop repeat DUF4535 PF15054.6 KXX80874.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Ras PF00071.22 KXX80875.1 - 3.5e-44 150.3 0.1 4.4e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX80875.1 - 1.4e-11 44.6 0.0 2.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX80875.1 - 5.6e-06 25.9 0.1 7.3e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXX80875.1 - 0.00075 19.1 0.0 0.00091 18.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain fn3_PAP PF17808.1 KXX80875.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase RsgA_GTPase PF03193.16 KXX80875.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase DUF3357 PF11837.8 KXX80876.1 - 0.044 14.3 0.0 0.16 12.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF5305 PF17231.2 KXX80876.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RNA_pol_Rpb1_6 PF04992.14 KXX80876.1 - 0.11 12.4 0.1 1.1 9.1 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 6 EGF_2 PF07974.13 KXX80876.1 - 1.6 9.1 11.5 2.9 8.4 11.5 1.4 1 0 0 1 1 1 0 EGF-like domain CMS1 PF14617.6 KXX80878.1 - 1e-93 313.3 2.1 1.1e-93 313.2 2.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KXX80878.1 - 2e-08 34.2 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1752 PF08550.10 KXX80879.1 - 0.06 13.2 0.8 0.14 12.0 0.8 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) Pkinase PF00069.25 KXX80881.1 - 4.5e-22 78.7 0.0 5.1e-10 39.2 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX80881.1 - 4.1e-10 39.4 0.3 0.00029 20.2 0.1 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXX80881.1 - 0.0011 18.3 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX80881.1 - 0.0018 18.3 1.2 0.005 16.8 0.1 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXX80881.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KXX80881.1 - 0.24 11.0 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Amidase PF01425.21 KXX80882.1 - 6.7e-94 315.4 3.4 6.1e-50 170.5 4.9 2.3 2 1 0 2 2 2 2 Amidase DUF4336 PF14234.6 KXX80883.1 - 2.1e-14 53.5 0.0 8.7e-09 35.0 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4336) Lactamase_B_5 PF14597.6 KXX80883.1 - 0.063 12.8 0.1 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily WD40 PF00400.32 KXX80884.1 - 3.4e-22 78.3 12.4 2.4e-06 28.1 1.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX80884.1 - 0.0057 16.9 0.0 0.21 11.9 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXX80884.1 - 0.0058 17.1 1.1 3.4 8.3 0.0 3.9 5 0 0 5 5 5 1 PQQ-like domain Cytochrom_D1 PF02239.16 KXX80884.1 - 0.048 12.2 2.4 6.5 5.2 0.1 3.4 4 0 0 4 4 4 0 Cytochrome D1 heme domain PD40 PF07676.12 KXX80884.1 - 0.13 12.2 1.5 3.1 7.8 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MmgE_PrpD PF03972.14 KXX80885.1 - 1.1e-151 505.3 0.0 1.4e-151 505.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Carboxyl_trans PF01039.22 KXX80886.1 - 1.2e-134 449.6 0.0 1.7e-134 449.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KXX80886.1 - 0.0033 16.9 0.2 2.3 7.6 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.24 KXX80887.1 - 2.5e-43 147.9 1.8 5.3e-43 146.8 1.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXX80887.1 - 6e-30 104.2 0.1 1.3e-29 103.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXX80887.1 - 4.2e-26 91.0 0.1 7.6e-26 90.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXX80887.1 - 4.7e-14 52.8 2.6 7.2e-14 52.2 0.2 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXX80887.1 - 0.0044 16.7 0.1 0.01 15.5 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal NUDIX PF00293.28 KXX80888.1 - 8.3e-09 35.6 0.0 6.8e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.18 KXX80889.1 - 2.3e-15 56.7 0.0 3e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Zn_ribbon_17 PF17120.5 KXX80890.1 - 1.8e-09 37.1 13.9 1.8e-09 37.1 13.9 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KXX80890.1 - 4.2e-06 27.4 18.2 0.0068 17.2 0.3 5.4 4 0 0 4 4 4 2 WD domain, G-beta repeat RWD PF05773.22 KXX80890.1 - 0.0024 18.1 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain Arabinose_Isome PF02610.15 KXX80890.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 L-arabinose isomerase zf-RING_2 PF13639.6 KXX80890.1 - 1.5 9.3 9.1 4.2 7.8 9.1 1.8 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.26 KXX80891.1 - 2.7e-47 159.9 0.0 3.1e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX80891.1 - 0.0003 20.5 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXX80891.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KXX80891.1 - 0.096 13.0 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain ADH_zinc_N PF00107.26 KXX80893.1 - 2.7e-14 53.3 0.0 7.8e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX80893.1 - 0.043 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ribosomal_L12 PF00542.19 KXX80893.1 - 0.12 12.8 0.2 0.29 11.5 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain PI3Ka PF00613.20 KXX80894.1 - 2.2e-56 190.2 1.8 4e-56 189.4 1.8 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KXX80894.1 - 3.2e-47 161.5 0.1 6.3e-32 111.3 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KXX80894.1 - 3.4e-34 117.7 0.0 6.3e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 KXX80895.1 - 7.9e-36 122.2 0.0 2.1e-35 120.8 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KXX80895.1 - 3e-20 72.1 0.0 1e-19 70.4 0.0 2.0 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE UPF0302 PF08864.10 KXX80895.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 UPF0302 domain ApbA PF02558.16 KXX80896.1 - 8.2e-20 71.0 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXX80896.1 - 3.6e-14 53.0 0.0 5.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sas10_Utp3 PF04000.15 KXX80897.1 - 1.6e-15 57.5 2.4 1.6e-15 57.5 2.4 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CdvA PF18822.1 KXX80897.1 - 0.0085 15.9 4.9 2.3 8.0 0.1 2.9 3 0 0 3 3 3 2 CdvA-like coiled-coil domain Glu-tRNAGln PF02686.15 KXX80897.1 - 0.037 14.3 2.2 0.096 13.0 0.6 2.2 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Spectrin PF00435.21 KXX80897.1 - 0.13 12.8 1.9 0.82 10.2 1.0 2.1 2 0 0 2 2 2 0 Spectrin repeat YabA PF06156.13 KXX80897.1 - 2 9.1 5.5 7 7.3 0.0 2.3 2 1 0 2 2 2 0 Initiation control protein YabA Coq4 PF05019.13 KXX80898.1 - 1.3e-96 322.2 0.0 1.6e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GAF_2 PF13185.6 KXX80898.1 - 0.13 12.6 0.0 12 6.1 0.0 2.7 3 0 0 3 3 3 0 GAF domain dsDNA_bind PF01984.20 KXX80899.1 - 4.4e-42 142.8 16.6 5.2e-42 142.6 16.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.6 KXX80899.1 - 0.05 14.2 0.8 0.05 14.2 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) EF-1_beta_acid PF10587.9 KXX80899.1 - 0.057 13.9 2.7 0.057 13.9 2.7 4.0 5 1 0 5 5 5 0 Eukaryotic elongation factor 1 beta central acidic region LAMTOR PF15454.6 KXX80899.1 - 1.6 9.4 8.2 0.78 10.4 1.8 2.3 2 1 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Tom5 PF10642.9 KXX80899.1 - 2 8.5 4.2 4.3 7.4 2.1 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase SURF1 PF02104.15 KXX80900.1 - 2.3e-49 168.0 0.0 3e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 KXX80901.1 - 1.8e-49 166.3 0.1 3.1e-49 165.6 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXX80901.1 - 9.6e-10 38.7 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KXX80901.1 - 3.3e-05 24.2 0.0 6.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXX80901.1 - 0.0004 20.6 0.0 0.00077 19.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2076 PF09849.9 KXX80902.1 - 1.7e-07 31.6 14.0 2.2e-07 31.2 14.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KXX80902.1 - 1.4e-05 25.1 3.5 1.9e-05 24.7 3.0 1.5 1 1 1 2 2 2 1 CHCH domain GCK PF07802.11 KXX80902.1 - 0.0015 18.9 0.4 0.0026 18.1 0.4 1.4 1 1 0 1 1 1 1 GCK domain Trypan_glycop_C PF10659.9 KXX80902.1 - 0.03 14.7 2.9 0.056 13.8 2.9 1.4 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain CX9C PF16860.5 KXX80902.1 - 0.072 13.1 3.2 0.11 12.5 2.4 1.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UBX PF00789.20 KXX80903.1 - 8.4e-15 54.7 0.0 1.8e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain SelK_SelG PF10961.8 KXX80903.1 - 0.0012 19.4 0.0 0.0031 18.1 0.0 1.7 1 0 0 1 1 1 1 Selenoprotein SelK_SelG DUF3446 PF11928.8 KXX80903.1 - 0.013 15.8 6.0 0.29 11.5 0.0 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain TFIIA PF03153.13 KXX80903.1 - 0.045 13.7 12.2 0.058 13.4 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5523 PF17661.1 KXX80903.1 - 0.061 13.0 11.7 0.11 12.2 11.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Bud13 PF09736.9 KXX80903.1 - 0.26 11.7 12.4 0.53 10.7 12.4 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex ERM PF00769.19 KXX80903.1 - 0.73 9.6 24.4 1.2 9.0 24.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Borrelia_P83 PF05262.11 KXX80903.1 - 2 6.8 16.1 2.6 6.5 16.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF966 PF06136.13 KXX80903.1 - 2.2 7.9 12.2 2.8 7.6 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hamartin PF04388.12 KXX80903.1 - 2.4 6.7 12.0 2.9 6.4 12.0 1.1 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 KXX80903.1 - 3.5 6.9 25.4 6.2 6.1 25.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_13 PF13166.6 KXX80903.1 - 8.9 4.8 11.3 11 4.5 11.3 1.1 1 0 0 1 1 1 0 AAA domain MAJIN PF15077.6 KXX80903.1 - 9.9 5.9 13.0 17 5.1 13.0 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein RRM_1 PF00076.22 KXX80904.1 - 0.0052 16.6 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 KXX80905.1 - 7.6e-14 52.5 0.0 1.1e-13 52.0 0.0 1.2 1 0 0 1 1 1 1 SET domain UBA_6 PF18039.1 KXX80906.1 - 0.042 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain DnaJ_C PF01556.18 KXX80909.1 - 3.1e-39 134.4 0.3 4.2e-39 134.0 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXX80909.1 - 8.2e-27 93.1 3.7 1.3e-26 92.5 3.7 1.3 1 0 0 1 1 1 1 DnaJ domain Zn_clus PF00172.18 KXX80910.1 - 9.9e-08 32.0 11.7 1.9e-07 31.1 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX80910.1 - 0.00051 19.0 0.0 0.00073 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.27 KXX80911.1 - 1.8e-56 190.8 0.0 2.4e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXX80911.1 - 1.2e-24 86.7 0.0 2.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXX80911.1 - 2e-15 56.9 2.9 2e-15 56.9 2.9 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXX80911.1 - 3.2e-05 24.0 0.0 6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX80911.1 - 0.026 14.5 0.0 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 KXX80911.1 - 0.052 13.1 0.2 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KXX80911.1 - 0.056 13.2 0.1 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thioredoxin PF00085.20 KXX80912.1 - 9.7e-62 205.4 0.0 1.1e-29 102.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KXX80912.1 - 3.7e-27 95.0 2.0 8.4e-27 93.9 0.9 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KXX80912.1 - 3.5e-18 66.1 0.0 1.4e-08 35.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXX80912.1 - 4.8e-15 55.7 0.0 7.1e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXX80912.1 - 2.9e-11 43.5 0.0 0.00045 20.5 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KXX80912.1 - 3.7e-09 36.6 0.1 0.003 17.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 KXX80912.1 - 2.5e-08 34.0 2.0 0.0013 18.8 0.0 2.8 3 0 0 3 3 2 2 Thioredoxin-like HyaE PF07449.11 KXX80912.1 - 2.6e-07 30.6 0.0 0.0086 16.0 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KXX80912.1 - 2.8e-07 30.6 0.0 0.0041 17.0 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KXX80912.1 - 5.2e-06 26.2 0.5 0.088 12.5 0.2 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 KXX80912.1 - 0.00021 21.1 0.0 0.26 11.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 KXX80912.1 - 0.0003 21.0 0.1 0.93 9.8 0.1 3.0 2 1 0 2 2 2 2 Glutaredoxin Thioredoxin_3 PF13192.6 KXX80912.1 - 0.0004 20.4 0.0 0.64 10.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.6 KXX80912.1 - 0.0014 18.8 2.6 0.59 10.3 0.1 3.6 2 2 2 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KXX80912.1 - 0.0016 18.4 0.1 0.05 13.5 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain DSBA PF01323.20 KXX80912.1 - 0.019 14.7 1.4 6.9 6.4 0.1 3.6 3 1 1 4 4 4 0 DSBA-like thioredoxin domain Ribosomal_S14 PF00253.21 KXX80913.1 - 2.5e-14 52.7 2.7 2.9e-14 52.6 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-RING_2 PF13639.6 KXX80914.1 - 4.8e-08 33.2 2.5 4.8e-08 33.2 2.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXX80914.1 - 1.6e-07 31.5 3.8 7.6e-07 29.3 3.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXX80914.1 - 8.8e-07 28.7 5.8 4.1e-06 26.5 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX80914.1 - 1.1e-06 28.4 0.1 1.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX80914.1 - 2e-05 24.4 1.0 2e-05 24.4 1.0 1.6 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXX80914.1 - 4.6e-05 23.2 0.6 4.6e-05 23.2 0.6 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXX80914.1 - 0.00059 19.4 0.9 0.0014 18.2 0.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXX80914.1 - 0.00082 19.1 8.0 0.0027 17.4 0.7 3.1 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXX80914.1 - 0.0012 18.6 1.1 0.0012 18.6 1.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX80914.1 - 0.0053 16.7 9.1 0.0072 16.3 1.7 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXX80914.1 - 0.0077 16.3 0.8 0.019 15.0 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 KXX80914.1 - 0.03 12.2 0.3 0.099 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2921) zf-C3H2C3 PF17122.5 KXX80914.1 - 0.19 11.8 4.8 0.63 10.1 1.6 2.4 2 0 0 2 2 2 0 Zinc-finger RINGv PF12906.7 KXX80914.1 - 0.21 11.7 1.3 0.53 10.5 1.3 1.6 1 0 0 1 1 1 0 RING-variant domain HSBP1 PF06825.12 KXX80915.1 - 1.4e-15 56.9 1.7 1.6e-15 56.6 1.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 KXX80915.1 - 0.0015 18.9 0.1 0.0017 18.7 0.1 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Apolipoprotein PF01442.18 KXX80915.1 - 0.0038 17.1 0.1 0.0043 17.0 0.1 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Matrilin_ccoil PF10393.9 KXX80915.1 - 0.044 13.7 0.4 0.17 11.8 0.4 1.9 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.12 KXX80915.1 - 0.047 13.7 0.2 0.055 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Peptidase_C50 PF03568.17 KXX80915.1 - 0.061 12.4 0.0 0.063 12.4 0.0 1.0 1 0 0 1 1 1 0 Peptidase family C50 Rit1_C PF17184.4 KXX80916.1 - 4.6e-104 347.7 0.0 6.1e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KXX80916.1 - 7.9e-35 119.5 0.0 1.6e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain HAD_2 PF13419.6 KXX80917.1 - 2.1e-20 73.5 0.0 3.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX80917.1 - 1.2e-11 45.3 0.4 1.5e-10 41.7 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 KXX80917.1 - 6.6e-07 29.2 0.0 1.5e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 KXX80917.1 - 3.9e-06 26.8 0.0 7.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXX80917.1 - 0.025 15.0 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXX80917.1 - 0.034 14.3 0.0 8.6 6.5 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KXX80918.1 - 1.7e-31 109.2 0.0 2.4e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX80918.1 - 5.1e-07 29.7 10.5 8.6e-07 29.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.19 KXX80919.1 - 3e-73 242.0 65.7 1.8e-19 69.7 10.4 4.7 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.23 KXX80919.1 - 1e-23 84.3 0.1 2.3e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Peroxidase NAD_kinase PF01513.21 KXX80921.1 - 3.3e-72 243.1 0.0 6.1e-72 242.3 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase CBF_beta PF02312.17 KXX80921.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Core binding factor beta subunit DAGK_cat PF00781.24 KXX80921.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain IBR PF01485.21 KXX80922.1 - 1.8e-21 76.1 37.6 2.1e-16 59.9 3.9 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KXX80922.1 - 2.3e-19 69.8 0.0 4.4e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KXX80922.1 - 0.00049 20.4 9.9 0.00049 20.4 9.9 3.8 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KXX80922.1 - 0.00092 19.2 7.3 0.00092 19.2 7.3 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXX80922.1 - 0.0012 18.6 6.6 0.0038 16.9 6.6 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXX80922.1 - 0.0059 16.5 9.8 0.0059 16.5 9.8 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX80922.1 - 0.007 16.3 9.9 0.007 16.3 9.9 3.8 3 1 1 4 4 4 1 zinc-RING finger domain RXT2_N PF08595.11 KXX80922.1 - 2 8.4 4.7 2.8 7.9 0.9 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF2011 PF09428.10 KXX80923.1 - 4.1e-17 62.2 0.5 2.4e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Nop53 PF07767.11 KXX80923.1 - 5.7 6.2 26.6 0.32 10.4 19.3 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Ashwin PF15323.6 KXX80924.1 - 0.013 15.6 1.6 0.026 14.5 1.6 1.5 1 0 0 1 1 1 0 Developmental protein HAUS6_N PF14661.6 KXX80925.1 - 1.2e-65 221.3 4.3 1.8e-65 220.8 4.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF4050 PF13259.6 KXX80925.1 - 7 6.9 9.4 0.27 11.5 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) PfkB PF00294.24 KXX80926.1 - 3.9e-19 69.1 0.0 5.2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UDPGT PF00201.18 KXX80926.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Pyr_redox_3 PF13738.6 KXX80927.1 - 1.4e-11 44.2 0.0 7.9e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX80927.1 - 3.5e-11 42.9 0.1 1.4e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXX80927.1 - 1.4e-07 31.0 0.5 3e-06 26.6 0.1 2.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KXX80927.1 - 2.3e-06 26.3 0.0 0.00022 19.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 KXX80927.1 - 0.13 11.6 0.0 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ECH_1 PF00378.20 KXX80928.1 - 9.7e-45 152.8 0.0 4.5e-33 114.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX80928.1 - 1.2e-18 67.7 1.1 2.4e-17 63.4 1.2 2.4 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase PWI PF01480.17 KXX80929.1 - 3.1e-14 53.0 0.6 7.9e-14 51.7 0.6 1.8 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.20 KXX80930.1 - 1.8e-12 46.7 6.7 3.9e-12 45.7 6.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 Peptidase_M43 PF05572.13 KXX80931.1 - 1.5e-10 41.2 2.1 1.8e-10 41.0 1.4 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KXX80931.1 - 0.0031 17.7 1.5 0.022 14.9 0.8 2.0 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXX80931.1 - 0.0054 17.3 0.7 0.0088 16.6 0.7 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXX80931.1 - 0.0079 15.9 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXX80931.1 - 0.0095 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 KXX80931.1 - 0.043 13.7 0.7 0.059 13.3 0.7 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Sterile PF03015.19 KXX80931.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein Glyco_hydro_62 PF03664.13 KXX80932.1 - 3e-148 492.5 7.8 3.5e-148 492.2 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DUF3638 PF12340.8 KXX80933.1 - 1e-86 289.9 0.0 1.8e-86 289.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXX80933.1 - 1.3e-15 56.5 0.1 2.7e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Fer4_19 PF06902.11 KXX80933.1 - 0.23 11.6 0.5 3 8.0 0.1 2.7 3 0 0 3 3 3 0 Divergent 4Fe-4S mono-cluster DUF4239 PF14023.6 KXX80934.1 - 0.1 12.3 0.2 0.1 12.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) PAP2 PF01569.21 KXX80935.1 - 1.4e-14 54.0 6.6 6.1e-14 51.9 6.6 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KXX80935.1 - 0.038 14.1 2.2 0.8 9.8 0.0 2.8 2 1 1 3 3 3 0 Divergent PAP2 family Transmemb_17 PF09799.9 KXX80935.1 - 0.82 10.3 5.6 2.5 8.7 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein PAP2_3 PF14378.6 KXX80935.1 - 0.82 9.3 19.8 0.69 9.6 5.3 3.2 2 1 0 2 2 2 0 PAP2 superfamily EphA2_TM PF14575.6 KXX80936.1 - 1.2 10.1 0.0 1.2 10.1 0.0 2.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain MARVEL PF01284.23 KXX80936.1 - 1.5 8.9 19.2 3.3 7.7 19.3 1.5 1 1 0 1 1 1 0 Membrane-associating domain EBP PF05241.12 KXX80937.1 - 6.5e-54 182.1 6.4 2.9e-53 180.0 6.4 1.8 1 1 0 1 1 1 1 Emopamil binding protein LMBR1 PF04791.16 KXX80937.1 - 0.0088 15.0 1.1 0.014 14.3 1.1 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein TMEM208_SND2 PF05620.11 KXX80937.1 - 0.42 10.4 6.0 2.4 7.9 0.6 2.7 2 1 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 PAN_4 PF14295.6 KXX80938.1 - 8.2e-16 57.7 21.2 4.8e-05 23.2 0.9 4.7 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 KXX80938.1 - 4.6e-13 48.9 6.0 0.0074 16.2 0.1 4.7 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 KXX80938.1 - 3.8 7.4 21.3 5.6 6.9 1.8 4.7 4 0 0 4 4 4 0 PAN-like domain Grg1 PF11034.8 KXX80939.1 - 5.2e-33 113.1 11.2 5.8e-33 112.9 11.2 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 NDT80_PhoG PF05224.12 KXX80940.1 - 6.3e-39 134.1 0.0 1.9e-38 132.6 0.0 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF3402 PF11882.8 KXX80941.1 - 1.3e-208 693.7 2.6 6.8e-205 681.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KXX80941.1 - 4.4e-95 318.2 0.0 4.4e-95 318.2 0.0 2.1 2 0 0 2 2 1 1 N1221-like protein Neur_chan_memb PF02932.16 KXX80941.1 - 0.013 15.6 6.1 0.026 14.6 6.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 KXX80941.1 - 0.051 13.6 14.7 0.099 12.7 14.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PLAC9 PF15205.6 KXX80941.1 - 0.11 12.8 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 Placenta-specific protein 9 TFIIA PF03153.13 KXX80941.1 - 0.13 12.2 47.0 0.32 10.9 47.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 KXX80941.1 - 0.14 12.4 21.1 0.27 11.5 21.1 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SLC12 PF03522.15 KXX80941.1 - 0.26 10.3 8.4 0.36 9.8 8.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 KXX80941.1 - 0.39 9.6 5.0 0.59 9.0 5.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TCP PF03634.13 KXX80941.1 - 0.79 10.3 11.3 1.6 9.3 11.3 1.4 1 0 0 1 1 1 0 TCP family transcription factor Raftlin PF15250.6 KXX80941.1 - 0.94 8.2 10.1 1.6 7.4 10.1 1.2 1 0 0 1 1 1 0 Raftlin SpoIIP PF07454.11 KXX80941.1 - 1.4 8.3 11.7 2.6 7.4 11.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 KXX80941.1 - 1.6 7.6 18.0 2.3 7.1 18.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WASH-7_C PF14746.6 KXX80941.1 - 1.9 8.1 10.7 4.1 7.1 10.7 1.5 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Presenilin PF01080.17 KXX80941.1 - 2.2 7.0 19.0 3.8 6.2 19.0 1.3 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 KXX80941.1 - 2.8 7.0 25.1 4.7 6.2 25.1 1.2 1 0 0 1 1 1 0 SprA-related family V_ATPase_I PF01496.19 KXX80941.1 - 3.7 5.4 10.7 5.6 4.8 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4770 PF15994.5 KXX80941.1 - 4.1 7.6 16.0 10 6.3 16.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CLN3 PF02487.17 KXX80941.1 - 4.7 6.2 5.8 7.6 5.5 5.8 1.2 1 0 0 1 1 1 0 CLN3 protein BRF1 PF07741.13 KXX80941.1 - 4.9 7.6 9.1 18 5.8 9.1 1.9 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Endostatin PF06482.11 KXX80941.1 - 7.3 6.0 15.2 14 5.1 15.2 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PUD1_2 PF18457.1 KXX80942.1 - 1.4e-57 194.5 1.5 1.6e-57 194.4 1.5 1.0 1 0 0 1 1 1 1 Up-Regulated in long-lived daf-2 ABC_tran PF00005.27 KXX80943.1 - 1.6e-48 164.7 0.0 6.1e-28 98.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXX80943.1 - 5.5e-30 104.9 28.3 4.7e-28 98.6 11.9 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KXX80943.1 - 3e-12 47.0 1.0 0.0033 17.3 0.0 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX80943.1 - 3.7e-12 46.2 2.2 4.6e-05 23.0 1.2 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXX80943.1 - 1.5e-06 28.7 0.5 0.045 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXX80943.1 - 2.1e-06 28.1 3.3 0.056 13.7 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_23 PF13476.6 KXX80943.1 - 1.5e-05 25.6 1.3 0.028 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXX80943.1 - 1.7e-05 24.8 0.2 0.018 15.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXX80943.1 - 2.9e-05 23.7 1.2 0.02 14.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXX80943.1 - 5.4e-05 23.3 0.6 0.23 11.5 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 KXX80943.1 - 0.00013 21.1 0.1 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 KXX80943.1 - 0.00018 21.1 0.1 0.49 9.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 KXX80943.1 - 0.00027 20.8 0.0 0.08 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KXX80943.1 - 0.00066 19.8 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXX80943.1 - 0.0022 17.6 1.6 0.47 10.0 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KXX80943.1 - 0.0023 18.3 0.4 1.1 9.7 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXX80943.1 - 0.0032 18.0 0.0 2.5 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KXX80943.1 - 0.005 16.2 0.4 1.4 8.2 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KXX80943.1 - 0.0068 16.1 0.1 2.6 7.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXX80943.1 - 0.0074 16.7 0.0 1.6 9.1 0.0 2.8 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.12 KXX80943.1 - 0.0087 16.0 0.9 1.7 8.6 0.0 3.0 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 KXX80943.1 - 0.012 15.3 1.7 0.37 10.5 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KXX80943.1 - 0.013 15.2 0.0 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXX80943.1 - 0.021 14.8 0.0 5.4 6.9 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KXX80943.1 - 0.022 14.5 0.1 0.37 10.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KXX80943.1 - 0.024 14.4 4.0 8.7 6.0 0.2 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KXX80943.1 - 0.024 14.4 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KXX80943.1 - 0.03 13.9 0.7 0.73 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXX80943.1 - 0.032 13.4 1.0 3.1 6.9 0.0 2.8 4 0 0 4 4 4 0 NB-ARC domain AAA_5 PF07728.14 KXX80943.1 - 0.033 14.2 0.4 5.7 6.9 0.2 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 KXX80943.1 - 0.037 14.2 0.3 17 5.6 0.1 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KXX80943.1 - 0.045 13.8 0.4 0.95 9.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 KXX80943.1 - 0.047 13.0 0.4 7.8 5.7 0.1 2.2 2 0 0 2 2 2 0 Septin MobB PF03205.14 KXX80943.1 - 0.047 13.6 0.2 3 7.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 KXX80943.1 - 0.052 12.8 0.1 3 7.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KXX80943.1 - 0.053 12.9 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 KXX80943.1 - 0.092 13.0 0.1 17 5.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KXX80943.1 - 0.096 12.3 0.1 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 KXX80943.1 - 0.097 12.6 0.8 11 5.9 0.1 2.5 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 KXX80943.1 - 0.19 11.7 0.2 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXX80943.1 - 0.24 11.4 0.5 4.8 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 KXX80943.1 - 0.27 11.1 1.0 0.48 10.3 0.1 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain DEAD PF00270.29 KXX80943.1 - 0.28 10.9 1.4 4.7 7.0 1.4 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.17 KXX80943.1 - 0.32 11.0 1.9 0.92 9.6 0.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Condensation PF00668.20 KXX80944.1 - 0 1298.6 0.0 3.2e-62 210.7 0.0 11.2 10 3 0 10 10 10 9 Condensation domain AMP-binding PF00501.28 KXX80944.1 - 0 1108.1 6.9 1.1e-77 261.5 0.3 6.6 6 1 0 6 6 6 6 AMP-binding enzyme PP-binding PF00550.25 KXX80944.1 - 4.2e-72 238.4 17.5 9e-12 45.2 0.0 9.0 9 0 0 9 9 9 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXX80944.1 - 1.1e-13 51.9 1.2 0.23 12.4 0.0 6.4 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KXX80944.1 - 5.4e-08 31.9 0.0 0.17 10.5 0.0 5.6 7 0 0 7 7 7 3 Transferase family DUF3658 PF12395.8 KXX80944.1 - 0.095 12.6 2.7 2.3 8.2 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function RHH_3 PF12651.7 KXX80944.1 - 0.2 11.7 0.1 0.52 10.3 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain DUF5122 PF17164.4 KXX80944.1 - 1.2 9.5 3.9 34 4.9 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller FAD_binding_4 PF01565.23 KXX80946.1 - 1.5e-11 44.2 0.1 8.4e-10 38.5 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXX80946.1 - 4.3e-06 26.7 0.2 0.037 13.8 0.0 2.4 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.11 KXX80946.1 - 0.011 14.7 0.2 0.2 10.6 0.1 2.3 2 1 1 3 3 3 0 Cholesterol oxidase, substrate-binding HTH_38 PF13936.6 KXX80946.1 - 0.17 11.7 0.0 0.53 10.1 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C2H2_4 PF13894.6 KXX80947.1 - 3.8e-08 33.5 10.6 0.019 15.7 0.7 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX80947.1 - 4.3e-07 30.0 10.7 0.00049 20.4 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KXX80947.1 - 0.00011 22.4 5.0 0.00045 20.5 2.0 2.6 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KXX80947.1 - 0.0014 19.0 22.2 0.0086 16.5 2.2 4.5 4 1 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KXX80947.1 - 0.11 12.3 13.6 0.72 9.7 1.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KXX80947.1 - 0.31 11.4 3.3 5 7.5 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX80947.1 - 0.81 10.2 3.3 14 6.3 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXX80947.1 - 1.7 9.0 6.3 9.6 6.6 1.1 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KXX80947.1 - 9.3 6.4 10.7 0.54 10.3 0.8 2.7 2 1 0 2 2 2 0 BED zinc finger Methyltransf_25 PF13649.6 KXX80948.1 - 7.6e-16 58.6 0.0 1.5e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX80948.1 - 3.5e-14 52.8 0.0 4.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX80948.1 - 6.5e-13 49.1 0.0 1.5e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX80948.1 - 2.5e-09 37.8 0.0 4.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX80948.1 - 3.1e-09 36.9 0.0 4.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX80948.1 - 1.6e-06 27.7 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXX80948.1 - 1.3e-05 25.4 0.0 1.8e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KXX80948.1 - 0.0008 18.8 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 KXX80948.1 - 0.002 18.2 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_19 PF04672.12 KXX80948.1 - 0.0021 17.6 0.0 0.025 14.1 0.0 2.0 1 1 0 1 1 1 1 S-adenosyl methyltransferase NodS PF05401.11 KXX80948.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) CheR PF01739.18 KXX80948.1 - 0.025 14.1 0.0 2.2 7.7 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain RrnaAD PF00398.20 KXX80948.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 KXX80948.1 - 0.21 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.14 KXX80948.1 - 0.25 10.7 0.0 0.47 9.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF4357 PF14267.6 KXX80949.1 - 0.57 10.2 3.0 1 9.3 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) HET PF06985.11 KXX80950.1 - 2.9e-25 89.3 0.0 5.2e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 KXX80950.1 - 0.00068 19.7 0.6 0.0016 18.5 0.6 1.6 1 0 0 1 1 1 1 WW domain Chorismate_bind PF00425.18 KXX80951.1 - 5.9e-49 167.0 0.0 1.8e-47 162.1 0.0 2.3 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KXX80951.1 - 1.1e-28 100.2 0.0 1.1e-27 97.0 0.0 2.6 3 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region HET PF06985.11 KXX80953.1 - 5.7e-33 114.3 0.1 9.1e-33 113.7 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.31 KXX80954.1 - 3.6e-07 30.4 0.1 2.5e-06 27.7 0.0 2.3 3 0 0 3 3 3 1 BTB/POZ domain NAD_binding_2 PF03446.15 KXX80955.1 - 8.2e-12 45.6 0.0 1.3e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXX80955.1 - 9e-07 29.4 0.0 1.9e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXX80955.1 - 0.031 14.3 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KXX80955.1 - 0.068 13.1 0.1 0.25 11.3 0.0 1.8 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cu_bind_like PF02298.17 KXX80956.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Glyco_hydro_45 PF02015.16 KXX80957.1 - 5.9e-80 268.1 15.5 6.9e-80 267.9 15.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 RNA_pol_Rpb2_6 PF00562.28 KXX80958.1 - 9.6e-125 416.7 0.0 1.4e-124 416.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXX80958.1 - 1.8e-52 177.8 0.0 2.6e-50 170.8 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KXX80958.1 - 8.5e-47 159.2 0.0 1.9e-46 158.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXX80958.1 - 1.2e-33 115.3 0.1 3e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KXX80958.1 - 7.8e-26 90.1 0.1 2.3e-25 88.5 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KXX80958.1 - 7.4e-24 84.1 0.1 2.1e-23 82.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KXX80958.1 - 8.8e-22 77.2 0.5 2e-21 76.0 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 PET117 PF15786.5 KXX80959.1 - 5.3e-26 90.7 2.7 6.4e-26 90.4 2.7 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial V-ATPase_G PF03179.15 KXX80960.1 - 4.8e-26 91.3 19.9 5.9e-26 91.1 19.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit YusW PF14039.6 KXX80960.1 - 0.0033 17.9 4.9 0.0048 17.4 4.9 1.3 1 0 0 1 1 1 1 YusW-like protein RGS-like PF09128.11 KXX80960.1 - 0.12 12.1 4.5 0.15 11.7 4.5 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF3552 PF12072.8 KXX80960.1 - 0.2 11.1 20.8 0.047 13.1 12.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP11 PF06644.11 KXX80960.1 - 0.23 11.2 10.3 0.27 11.0 10.3 1.0 1 0 0 1 1 1 0 ATP11 protein AAA_11 PF13086.6 KXX80960.1 - 0.24 11.2 7.5 0.3 10.8 7.5 1.0 1 0 0 1 1 1 0 AAA domain DUF5398 PF17376.2 KXX80960.1 - 0.4 11.3 8.1 0.19 12.4 5.2 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5398) V-ATPase_G_2 PF16999.5 KXX80960.1 - 0.43 11.0 21.3 0.85 10.1 21.3 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit UPF0029 PF01205.19 KXX80960.1 - 0.49 10.8 3.8 0.71 10.2 3.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Asp-B-Hydro_N PF05279.11 KXX80960.1 - 0.53 10.3 12.2 0.63 10.1 12.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Metal_resist PF13801.6 KXX80960.1 - 1.3 9.3 10.3 3.1 8.0 10.3 1.6 1 1 0 1 1 1 0 Heavy-metal resistance DUF4407 PF14362.6 KXX80960.1 - 2.2 7.5 9.3 2.6 7.3 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.18 KXX80960.1 - 5.8 7.0 25.1 2.9 8.0 11.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) FAD_binding_4 PF01565.23 KXX80961.1 - 6.1e-25 87.6 2.1 6.7e-25 87.4 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain Glyco_hydro_43 PF04616.14 KXX80963.1 - 1.6e-68 231.2 1.9 2e-68 230.8 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXX80963.1 - 1.3e-14 54.4 0.0 2.3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Reg_prop PF07494.11 KXX80963.1 - 0.019 15.1 1.3 5 7.7 0.0 3.9 4 0 0 4 4 4 0 Two component regulator propeller Glyco_hydro_32N PF00251.20 KXX80963.1 - 0.083 12.4 0.2 0.74 9.3 0.0 2.4 3 0 0 3 3 3 0 Glycosyl hydrolases family 32 N-terminal domain Ifi-6-16 PF06140.13 KXX80965.1 - 4.5e-08 32.9 0.0 8.8e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family VPR PF00522.18 KXX80965.1 - 0.17 11.9 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 VPR/VPX protein BTB_2 PF02214.22 KXX80966.1 - 1.9e-11 44.2 0.0 3.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXX80966.1 - 0.00042 20.5 0.0 0.00068 19.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Abhydrolase_1 PF00561.20 KXX80968.1 - 9e-21 74.7 0.2 5.4e-20 72.1 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX80968.1 - 6.4e-17 62.9 6.0 7.7e-17 62.6 6.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX80968.1 - 1.7e-15 56.9 0.0 5.4e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXX80968.1 - 0.029 14.5 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KXX80968.1 - 0.038 13.7 0.2 0.46 10.2 0.2 2.1 1 1 0 1 1 1 0 PGAP1-like protein Regnase_1_C PF18561.1 KXX80968.1 - 0.054 13.2 0.5 1.5 8.7 0.1 3.0 3 1 1 4 4 4 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Lipase_3 PF01764.25 KXX80968.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Ubie_methyltran PF01209.18 KXX80969.1 - 4.1e-10 39.4 0.0 7.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXX80969.1 - 2.8e-09 37.6 0.0 5.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX80969.1 - 1e-07 32.5 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX80969.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Glyco_hydro_36C PF16874.5 KXX80969.1 - 0.0092 16.4 0.0 0.15 12.6 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 36 C-terminal domain DUF982 PF06169.12 KXX80969.1 - 0.098 12.7 0.5 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF982) VHL_C PF17211.3 KXX80970.1 - 0.063 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 VHL box domain DUF4149 PF13664.6 KXX80971.1 - 9e-23 80.5 0.3 1.3e-22 80.0 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) Erg28 PF03694.13 KXX80971.1 - 0.079 13.3 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Erg28 like protein CTNNBL PF08216.11 KXX80972.1 - 2.2e-36 124.1 0.0 7.2e-36 122.5 0.0 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear GFA PF04828.14 KXX80973.1 - 1.1e-19 70.6 0.3 1.5e-19 70.1 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme B_lectin PF01453.24 KXX80974.1 - 4.4e-06 27.2 0.1 2.9e-05 24.6 0.1 1.9 1 1 1 2 2 2 1 D-mannose binding lectin BofC_C PF08955.10 KXX80974.1 - 0.049 13.7 0.0 7.1 6.8 0.0 2.5 2 1 0 2 2 2 0 BofC C-terminal domain Tail_tube PF10618.9 KXX80974.1 - 0.081 12.8 1.7 9 6.2 0.3 2.3 2 1 0 2 2 2 0 Phage tail tube protein PQQ PF01011.21 KXX80974.1 - 0.16 12.0 3.9 0.31 11.0 1.0 2.7 2 1 1 3 3 3 0 PQQ enzyme repeat DUF1996 PF09362.10 KXX80975.1 - 2.7e-80 269.7 1.1 3.3e-80 269.5 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PQQ_2 PF13360.6 KXX80976.1 - 3.6e-13 49.6 3.8 3.2e-06 26.9 1.5 3.6 2 2 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KXX80976.1 - 2.1e-07 30.6 8.5 0.061 13.3 0.1 6.3 6 0 0 6 6 6 3 PQQ enzyme repeat PQQ_3 PF13570.6 KXX80976.1 - 2.4e-07 31.0 34.2 0.00036 20.9 1.1 8.5 8 0 0 8 8 8 4 PQQ-like domain Colicin_E5 PF12106.8 KXX80976.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Colicin E5 ribonuclease domain ketoacyl-synt PF00109.26 KXX80977.1 - 7.1e-65 219.1 0.0 1e-64 218.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXX80977.1 - 6.4e-35 119.7 0.4 6.2e-34 116.5 0.4 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KXX80977.1 - 1.9e-23 83.5 0.0 2.9e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KXX80977.1 - 8e-18 64.9 0.0 1.5e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXX80977.1 - 0.00032 20.1 0.1 0.00074 18.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain SpoVAD PF07451.11 KXX80977.1 - 0.0066 15.2 0.5 0.012 14.3 0.1 1.5 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KXX80977.1 - 0.013 15.3 0.1 0.054 13.3 0.1 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAT PF16073.5 KXX80977.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF676 PF05057.14 KXX80977.1 - 0.18 11.3 0.1 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Cnn_1N PF07989.11 KXX80978.1 - 4e-09 36.5 13.8 4e-09 36.5 13.8 1.9 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 IFT20 PF14931.6 KXX80978.1 - 0.21 11.8 8.1 0.4 10.9 8.1 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Herpes_UL25 PF01499.16 KXX80978.1 - 0.23 9.9 2.2 0.46 9.0 2.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family adh_short PF00106.25 KXX80979.1 - 3.8e-23 82.0 0.2 5.5e-21 74.9 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX80979.1 - 1.5e-12 47.6 0.4 4.2e-11 42.9 0.4 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX80979.1 - 1.6e-05 24.9 0.4 3.4e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXX80979.1 - 0.13 11.7 0.2 0.64 9.4 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KXX80981.1 - 2.7e-22 79.0 1.1 4.7e-22 78.2 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX80981.1 - 5.1e-07 29.7 2.3 1.5e-06 28.2 2.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KXX80982.1 - 6.6e-20 71.4 0.0 9.3e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX80982.1 - 6.7e-10 38.9 0.0 1.1e-09 38.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX80982.1 - 2e-08 34.3 0.0 2.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX80982.1 - 0.00015 21.3 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF629 PF04780.12 KXX80982.1 - 0.074 11.6 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Transferase PF02458.15 KXX80983.1 - 4.7e-34 117.8 0.0 4.1e-28 98.2 0.0 2.0 2 0 0 2 2 2 2 Transferase family Condensation PF00668.20 KXX80983.1 - 0.15 10.7 0.1 0.33 9.6 0.1 1.5 1 0 0 1 1 1 0 Condensation domain p450 PF00067.22 KXX80984.1 - 1.7e-58 198.5 0.0 6.1e-58 196.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 Hydrolase_4 PF12146.8 KXX80985.1 - 5.2e-14 52.1 0.0 1.3e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXX80985.1 - 4.2e-09 37.3 0.0 5.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KXX80985.1 - 2e-08 33.3 0.1 0.002 16.9 0.1 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KXX80985.1 - 3.2e-05 23.7 0.0 0.00098 18.8 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXX80985.1 - 7.1e-05 22.5 0.0 9.2e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXX80985.1 - 0.0027 17.2 0.0 0.61 9.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXX80985.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1996 PF09362.10 KXX80986.1 - 7e-72 242.2 2.2 8.4e-72 241.9 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ETX_MTX2 PF03318.13 KXX80988.1 - 0.7 9.6 5.1 1.1 9.0 5.1 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Amino_oxidase PF01593.24 KXX80989.1 - 2.5e-40 139.1 0.2 4.6e-38 131.7 0.2 2.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX80989.1 - 2.3e-11 43.8 0.1 5.1e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX80989.1 - 5.1e-05 23.0 0.0 9.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX80989.1 - 6.8e-05 22.1 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX80989.1 - 9.1e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX80989.1 - 0.00053 18.8 0.1 0.00079 18.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein MCRA PF06100.11 KXX80989.1 - 0.00071 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 MCRA family FAD_oxidored PF12831.7 KXX80989.1 - 0.0046 16.4 0.0 0.0086 15.5 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXX80989.1 - 0.0068 16.9 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX80989.1 - 0.0085 15.4 0.2 0.013 14.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXX80989.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 KXX80989.1 - 0.21 10.6 0.1 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HET PF06985.11 KXX80990.1 - 1.5e-25 90.2 0.1 2.5e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Toxin_18 PF08087.11 KXX80992.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Conotoxin O-superfamily HET PF06985.11 KXX80993.1 - 4e-28 98.6 0.0 7.1e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Myb_DNA-binding PF00249.31 KXX80994.1 - 0.026 14.7 0.2 0.077 13.2 0.2 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Scs3p PF10261.9 KXX80995.1 - 3.5e-68 229.8 0.7 5.7e-68 229.1 0.7 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.9 KXX80995.1 - 2.4e-23 82.1 0.1 4.7e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase Glyco_hydro_47 PF01532.20 KXX80996.1 - 5.3e-168 559.6 0.0 6.1e-168 559.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA_12 PF13087.6 KXX80997.1 - 3.9e-41 140.9 0.0 9.2e-41 139.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXX80997.1 - 1.6e-40 138.6 0.0 3.4e-13 50.2 0.0 7.1 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXX80997.1 - 3.9e-31 108.8 29.6 1.5e-26 93.8 0.0 6.5 6 0 0 6 6 6 2 AAA domain AAA_30 PF13604.6 KXX80997.1 - 8.7e-21 74.5 1.5 0.00012 21.9 0.0 6.1 5 0 0 5 5 5 5 AAA domain AAA_19 PF13245.6 KXX80997.1 - 3.8e-15 56.5 0.0 1.3e-05 25.6 0.0 5.3 4 2 0 4 4 4 2 AAA domain AAA_lid_6 PF17866.1 KXX80997.1 - 1.4e-13 50.8 12.0 1.3e-06 28.5 0.3 3.7 3 0 0 3 3 3 2 AAA lid domain AAA_5 PF07728.14 KXX80997.1 - 5.1e-12 46.0 0.9 0.16 12.0 0.0 5.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX80997.1 - 7.5e-10 39.2 11.9 0.02 15.2 0.1 8.0 7 3 0 7 7 6 3 AAA domain Mg_chelatase PF01078.21 KXX80997.1 - 2.3e-09 37.0 0.5 0.061 12.7 0.0 4.9 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KXX80997.1 - 1.8e-08 34.4 0.0 0.48 10.1 0.0 5.9 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KXX80997.1 - 3.2e-08 33.5 0.5 0.71 9.6 0.0 5.3 6 0 0 6 6 4 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KXX80997.1 - 3.3e-07 30.2 0.0 2 8.1 0.0 4.5 4 0 0 4 4 4 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KXX80997.1 - 5.9e-07 29.9 0.2 1.8 9.0 0.0 4.7 4 0 0 4 4 4 1 RNA helicase AAA_7 PF12775.7 KXX80997.1 - 2e-06 27.4 0.1 1.6 8.2 0.0 4.7 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_16 PF13191.6 KXX80997.1 - 2.4e-06 28.0 13.4 1.2 9.5 0.0 6.3 6 0 0 6 6 5 3 AAA ATPase domain Torsin PF06309.11 KXX80997.1 - 3.9e-06 27.0 0.0 5.7 7.1 0.0 4.5 4 0 0 4 4 4 0 Torsin AAA_24 PF13479.6 KXX80997.1 - 4.3e-06 26.6 6.9 0.44 10.2 0.1 5.5 5 0 0 5 5 5 2 AAA domain AAA_17 PF13207.6 KXX80997.1 - 2.8e-05 24.5 11.9 0.031 14.7 0.0 5.9 5 0 0 5 5 5 1 AAA domain Sigma54_activat PF00158.26 KXX80997.1 - 7.1e-05 22.6 0.1 5.9 6.6 0.0 4.8 5 0 0 5 5 4 0 Sigma-54 interaction domain AAA_18 PF13238.6 KXX80997.1 - 9.1e-05 23.0 7.9 3.5 8.2 0.0 5.6 5 0 0 5 5 4 1 AAA domain TniB PF05621.11 KXX80997.1 - 0.00011 21.7 0.0 27 4.1 0.0 6.1 7 0 0 7 7 6 0 Bacterial TniB protein PhoH PF02562.16 KXX80997.1 - 0.00061 19.3 0.9 13 5.2 0.0 4.4 4 0 0 4 4 4 0 PhoH-like protein ResIII PF04851.15 KXX80997.1 - 0.0013 18.8 0.1 3.3 7.7 0.0 4.8 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 KXX80997.1 - 0.0031 17.7 21.0 0.78 9.9 0.1 6.5 6 0 0 6 6 5 2 AAA domain ATPase PF06745.13 KXX80997.1 - 0.019 14.3 2.6 16 4.8 0.0 4.3 4 0 0 4 4 4 0 KaiC NTPase_1 PF03266.15 KXX80997.1 - 0.023 14.6 6.4 22 4.9 0.1 4.7 5 0 0 5 5 4 0 NTPase AAA_10 PF12846.7 KXX80997.1 - 0.027 13.4 0.1 0.88 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA-like domain SRP54 PF00448.22 KXX80997.1 - 0.065 12.9 2.6 0.72 9.5 0.0 3.5 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 KXX80997.1 - 0.088 12.9 0.0 87 3.2 0.0 3.9 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 KXX80997.1 - 0.13 11.8 7.7 3 7.4 0.0 5.2 5 0 0 5 5 5 0 AAA domain DUF2075 PF09848.9 KXX80997.1 - 0.14 11.4 0.0 0.14 11.4 0.0 7.3 8 1 0 8 8 6 0 Uncharacterized conserved protein (DUF2075) AAA_6 PF12774.7 KXX80997.1 - 0.19 10.6 0.3 4.5 6.1 0.1 2.6 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region NACHT PF05729.12 KXX80997.1 - 0.36 10.7 4.2 42 4.0 0.0 4.4 4 0 0 4 4 4 0 NACHT domain YjbH PF06082.11 KXX80997.1 - 1.5 7.5 3.7 3 6.5 3.7 1.4 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH ADK PF00406.22 KXX80997.1 - 1.8 8.7 5.4 48 4.0 0.0 3.9 4 0 0 4 4 3 0 Adenylate kinase CbiA PF01656.23 KXX80997.1 - 4.1 7.5 5.2 31 4.6 0.0 3.9 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Med21 PF11221.8 KXX80998.1 - 0.39 11.0 1.3 0.9 9.8 1.3 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex MFS_1 PF07690.16 KXX80999.1 - 7.1e-20 71.2 83.5 7.8e-19 67.8 44.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YobH PF13996.6 KXX80999.1 - 0.026 14.5 1.1 0.026 14.5 1.1 2.9 3 0 0 3 3 3 0 YobH-like protein ISK_Channel PF02060.15 KXX80999.1 - 0.15 11.8 0.4 0.42 10.4 0.4 1.8 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Methyltransf_2 PF00891.18 KXX81000.1 - 1.9e-23 82.9 0.0 2.1e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KXX81000.1 - 0.17 11.7 0.0 4.4 7.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Cellulase PF00150.18 KXX81001.1 - 5.2e-20 72.0 0.4 9.4e-20 71.2 0.4 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AnkUBD PF18418.1 KXX81002.1 - 0.02 15.0 0.0 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Ankyrin ubiquitin-binding domain HRCT1 PF15758.5 KXX81002.1 - 0.023 15.7 0.0 0.39 11.7 0.0 2.3 2 0 0 2 2 2 0 Histidine-rich carboxyl terminus protein 1 Clr5 PF14420.6 KXX81002.1 - 0.18 12.0 0.8 0.45 10.8 0.8 1.7 1 0 0 1 1 1 0 Clr5 domain HET PF06985.11 KXX81003.1 - 3.6e-23 82.5 0.2 3.4e-22 79.4 0.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXX81004.1 - 1.5e-13 51.3 4.9 8.1e-11 42.5 0.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3872 PF12988.7 KXX81004.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) Pectate_lyase_3 PF12708.7 KXX81005.1 - 1.1e-99 332.6 13.3 1.1e-86 290.1 6.3 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXX81005.1 - 4.4e-08 32.7 0.1 0.004 16.8 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase AMP-binding PF00501.28 KXX81007.1 - 3.6e-67 226.8 0.0 4.5e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX81007.1 - 0.017 16.1 0.0 0.15 13.0 0.0 2.3 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 KXX81008.1 - 1.9e-77 260.3 0.0 3.8e-77 259.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXX81008.1 - 7.1e-76 255.5 0.0 9.6e-75 251.8 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KXX81008.1 - 4e-61 207.1 0.0 6.4e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KXX81008.1 - 1.5e-44 152.4 0.0 2.5e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX81008.1 - 1.3e-41 143.1 0.0 2.7e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KXX81008.1 - 7.5e-41 140.0 0.0 3e-39 134.8 0.0 2.5 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 KXX81008.1 - 1e-35 123.3 0.8 2.5e-33 115.5 0.1 2.8 3 0 0 3 3 2 1 KR domain Ketoacyl-synt_C PF02801.22 KXX81008.1 - 9.2e-32 109.5 0.0 2.1e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.21 KXX81008.1 - 3.8e-13 49.5 0.0 1.4e-11 44.3 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXX81008.1 - 1.2e-12 48.0 2.4 7.7e-06 26.2 0.2 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXX81008.1 - 1.1e-11 45.1 0.0 2.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension SAT PF16073.5 KXX81008.1 - 1.7e-05 24.6 0.5 3.7e-05 23.6 0.5 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short PF00106.25 KXX81008.1 - 2.5e-05 23.8 1.6 0.00014 21.4 0.1 2.8 3 0 0 3 3 3 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KXX81008.1 - 8.8e-05 21.6 0.0 0.00048 19.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 KXX81008.1 - 0.00025 20.5 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.6 KXX81008.1 - 0.0039 17.1 0.1 0.047 13.6 0.0 2.9 3 0 0 3 3 3 1 NAD(P)H-binding Methyltransf_12 PF08242.12 KXX81008.1 - 0.03 15.1 0.0 0.077 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXX81008.1 - 0.058 14.0 0.0 0.18 12.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXX81008.1 - 0.069 13.0 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ACP_syn_III PF08545.10 KXX81008.1 - 0.08 12.8 0.3 0.2 11.5 0.3 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_31 PF13847.6 KXX81008.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Toxin_29 PF08116.11 KXX81010.1 - 0.16 12.0 15.4 1.8 8.6 3.2 2.8 2 0 0 2 2 2 0 PhTx neurotoxin family BTB PF00651.31 KXX81011.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain GRDP-like PF07173.12 KXX81012.1 - 6.5e-20 72.2 1.6 1.9e-13 51.3 0.0 2.6 2 1 0 2 2 2 2 Glycine-rich domain-containing protein-like Glyco_hydro_7 PF00840.20 KXX81013.1 - 7.8e-148 492.8 1.6 8.9e-148 492.6 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Tyrosinase PF00264.20 KXX81014.1 - 2.2e-10 41.2 0.0 3.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_2 PF00703.21 KXX81015.1 - 0.063 13.9 0.3 1.9 9.2 0.0 2.4 1 1 1 2 2 2 0 Glycosyl hydrolases family 2 UCH PF00443.29 KXX81017.1 - 6.1e-34 117.7 0.0 8.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KXX81017.1 - 2.7e-25 87.9 1.8 1.4e-23 82.4 0.1 2.5 2 0 0 2 2 2 2 Variant UBP zinc finger zf-UBP PF02148.19 KXX81017.1 - 1.8e-22 79.4 17.3 2.7e-20 72.4 1.1 3.3 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KXX81017.1 - 1.9e-17 62.8 0.0 1.2e-09 37.9 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KXX81017.1 - 2.4e-16 60.2 1.3 3.2e-14 53.3 0.0 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase HORMA PF02301.18 KXX81018.1 - 4.6e-33 114.6 0.0 5.3e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KXX81018.1 - 0.00097 19.1 0.4 0.0046 16.9 0.4 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 PP_M1 PF03012.14 KXX81018.1 - 0.032 13.8 0.4 0.04 13.5 0.4 1.2 1 0 0 1 1 1 0 Phosphoprotein DUF2660 PF10859.8 KXX81018.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Ank_2 PF12796.7 KXX81019.1 - 6.2e-10 39.5 0.0 8.7e-07 29.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX81019.1 - 1.4e-07 31.6 5.3 0.88 10.1 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXX81019.1 - 3.3e-06 27.5 0.6 0.48 11.1 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX81019.1 - 9.4e-05 22.5 4.6 1 10.2 0.1 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KXX81019.1 - 0.00033 20.9 0.5 0.47 10.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TRP PF06011.12 KXX81020.1 - 3.8e-159 530.0 29.0 4.6e-159 529.7 29.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXX81020.1 - 3.4e-42 144.1 0.1 5.8e-42 143.4 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KXX81020.1 - 0.093 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 ML domain DUF4579 PF15158.6 KXX81020.1 - 0.41 10.4 3.1 0.83 9.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) DHHC PF01529.20 KXX81020.1 - 3.9 7.6 13.4 6.9 6.8 2.8 3.0 2 2 0 2 2 2 0 DHHC palmitoyltransferase adh_short PF00106.25 KXX81021.1 - 1e-38 132.8 0.0 1.3e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81021.1 - 7e-28 97.8 0.0 9.1e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXX81021.1 - 4.3e-05 23.5 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding DUF1776 PF08643.10 KXX81021.1 - 0.0068 15.8 0.0 0.0087 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KXX81021.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 KR domain RNase_H PF00075.24 KXX81022.1 - 1.4e-37 129.0 0.0 2.1e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KXX81022.1 - 1.5e-36 124.5 14.1 7.2e-19 67.8 3.3 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RVT_3 PF13456.6 KXX81022.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Beta-lactamase PF00144.24 KXX81025.1 - 2.7e-38 132.0 0.1 5.4e-38 131.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF420 PF04238.12 KXX81027.1 - 0.27 11.5 11.7 5.2 7.4 4.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF420) DUF1100 PF06500.11 KXX81029.1 - 4.3e-06 25.8 0.0 6.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 KXX81029.1 - 4.3e-06 27.5 1.2 4.3e-06 27.5 1.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXX81029.1 - 2.4e-05 23.9 0.0 4.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXX81029.1 - 0.0005 18.8 0.0 0.036 12.7 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXX81029.1 - 0.0034 16.7 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KXX81029.1 - 0.01 15.4 0.0 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KXX81029.1 - 0.019 14.6 0.0 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXX81029.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KXX81029.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 KXX81029.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Carb_bind PF10645.9 KXX81030.1 - 2.4e-15 56.5 6.9 5.3e-15 55.4 6.9 1.6 1 0 0 1 1 1 1 Carbohydrate binding Glyco_hydro_11 PF00457.17 KXX81032.1 - 2.1e-81 271.8 16.7 2.5e-81 271.6 16.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 HrpA_pilin PF09589.10 KXX81033.1 - 0.13 12.9 10.7 1.6 9.5 2.8 3.1 2 1 0 2 2 2 0 HrpA pilus formation protein AAA_23 PF13476.6 KXX81033.1 - 7.3 7.0 14.3 19 5.7 8.2 2.3 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KXX81034.1 - 8.3e-16 57.8 0.1 1.5e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX81034.1 - 3.9e-06 26.9 12.3 7.2e-06 26.0 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KXX81035.1 - 7.3e-74 249.2 0.0 8.5e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 KXX81036.1 - 4.2e-22 78.1 0.8 1.2e-21 76.7 0.8 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX81036.1 - 9.1e-22 77.4 1.4 1.4e-21 76.8 0.5 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXX81036.1 - 2.3e-08 33.8 0.9 2.3e-08 33.8 0.9 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXX81036.1 - 0.00086 18.7 3.8 0.0017 17.7 3.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXX81036.1 - 0.0093 17.0 0.1 0.048 14.7 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXX81036.1 - 0.017 15.4 0.3 0.029 14.6 0.3 1.3 1 0 0 1 1 1 0 TrkA-N domain Redoxin PF08534.10 KXX81036.1 - 0.024 14.4 0.4 3.9 7.2 0.1 2.3 1 1 1 2 2 2 0 Redoxin UDPG_MGDP_dh_N PF03721.14 KXX81036.1 - 0.076 12.6 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GMC_oxred_N PF00732.19 KXX81037.1 - 1.4e-48 165.8 0.0 1.9e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX81037.1 - 3e-30 105.6 0.2 5.1e-30 104.9 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXX81037.1 - 0.0022 17.1 0.1 0.025 13.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXX81037.1 - 0.0064 16.7 0.1 0.027 14.7 0.1 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXX81037.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KXX81037.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase EphA2_TM PF14575.6 KXX81038.1 - 0.0067 17.3 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KXX81038.1 - 0.0078 15.8 0.3 0.18 11.4 0.1 2.0 1 1 0 2 2 2 1 CD34/Podocalyxin family SKG6 PF08693.10 KXX81038.1 - 0.021 14.2 1.8 0.055 12.9 1.8 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Granulin PF00396.18 KXX81038.1 - 3.3 8.1 8.5 2.5 8.5 3.2 2.5 2 0 0 2 2 2 0 Granulin Atg14 PF10186.9 KXX81039.1 - 5.3e-18 65.2 0.1 1e-17 64.3 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KXX81039.1 - 2.4e-11 43.2 0.3 1.4e-07 30.7 0.0 2.9 3 0 0 3 3 3 2 Vacuolar protein sorting 38 DUF1996 PF09362.10 KXX81040.1 - 5.4e-80 268.7 0.9 6.3e-80 268.5 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lyase_1 PF00206.20 KXX81041.1 - 1.2e-87 294.2 0.0 1.7e-87 293.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KXX81041.1 - 1.7e-25 89.5 0.3 5.3e-25 88.0 0.1 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal YPEB PF14620.6 KXX81041.1 - 0.065 12.6 0.1 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 YpeB sporulation ATPgrasp_N PF18130.1 KXX81042.1 - 4.5e-23 81.6 0.0 1.2e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KXX81042.1 - 1.1e-10 41.3 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXX81042.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KXX81042.1 - 0.036 14.1 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Esterase_phd PF10503.9 KXX81042.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase PALP PF00291.25 KXX81043.1 - 1.1e-28 100.5 0.0 5.9e-28 98.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_31 PF13847.6 KXX81044.1 - 1.2e-21 77.1 0.0 2.7e-21 76.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81044.1 - 9.1e-16 58.4 0.0 1.1e-14 54.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX81044.1 - 1.8e-12 47.7 0.0 5.1e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX81044.1 - 4.6e-12 46.5 0.0 1.3e-11 45.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX81044.1 - 1.8e-09 37.6 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX81044.1 - 4.4e-07 29.5 0.0 9.1e-07 28.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXX81044.1 - 4.7e-06 26.0 0.0 7.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KXX81044.1 - 1.1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXX81044.1 - 4.4e-05 23.0 0.0 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KXX81044.1 - 0.00032 20.9 0.0 0.00045 20.4 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KXX81044.1 - 0.00056 19.3 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KXX81044.1 - 0.00098 18.8 0.0 0.0015 18.3 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 KXX81044.1 - 0.0014 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF1421 PF07223.11 KXX81044.1 - 0.0022 17.8 0.0 1.3 8.9 0.0 2.7 3 0 0 3 3 3 1 UBA-like domain (DUF1421) MetW PF07021.12 KXX81044.1 - 0.0023 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KXX81044.1 - 0.0043 17.1 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXX81044.1 - 0.0062 16.3 0.0 0.025 14.4 0.0 1.9 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 KXX81044.1 - 0.12 12.0 0.0 1.5 8.5 0.0 2.4 3 0 0 3 3 3 0 Putative RNA methylase family UPF0020 Ferric_reduct PF01794.19 KXX81045.1 - 6.9e-21 74.7 16.6 2e-20 73.1 16.6 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXX81045.1 - 4.5e-05 23.6 0.0 0.44 10.7 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXX81045.1 - 0.0081 16.2 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KXX81045.1 - 0.02 15.5 0.0 0.12 13.0 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Hist_deacetyl PF00850.19 KXX81045.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain DUF4293 PF14126.6 KXX81045.1 - 8.6 6.6 10.6 0.94 9.7 5.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) NifU_N PF01592.16 KXX81046.1 - 7.7e-55 184.5 0.0 9.8e-55 184.2 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1858 PF08984.11 KXX81046.1 - 0.081 13.1 0.1 0.28 11.4 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1858) TSCPD PF12637.7 KXX81046.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain PTR2 PF00854.21 KXX81047.1 - 5e-52 177.1 1.7 8e-52 176.4 1.7 1.3 1 1 0 1 1 1 1 POT family GPI2 PF06432.11 KXX81047.1 - 0.092 12.2 0.2 0.092 12.2 0.2 1.9 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Kinesin PF00225.23 KXX81049.1 - 9.3e-116 386.4 0.0 1.4e-115 385.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXX81049.1 - 9.2e-27 93.8 0.0 1.9e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 KXX81049.1 - 0.0014 18.9 1.8 0.0036 17.6 1.8 1.7 1 0 0 1 1 1 1 Herpesvirus UL14-like protein AAA_33 PF13671.6 KXX81049.1 - 0.047 13.9 0.0 0.2 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 KXX81050.1 - 7.3e-08 32.6 2.4 0.0031 18.2 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXX81050.1 - 9.3e-07 29.0 3.0 0.004 17.5 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type LicD PF04991.13 KXX81050.1 - 0.2 11.8 0.0 0.27 11.3 0.0 1.1 1 0 0 1 1 1 0 LicD family zf-Di19 PF05605.12 KXX81050.1 - 0.23 11.8 1.5 6 7.2 0.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_115 PF15979.5 KXX81051.1 - 5.9e-139 463.2 0.2 1e-138 462.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXX81051.1 - 4.3e-45 153.6 0.0 7.4e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Peptidase_A4 PF01828.17 KXX81052.1 - 1.3e-33 116.2 0.5 1.6e-33 116.0 0.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family Helo_like_N PF17111.5 KXX81053.1 - 8.5e-06 25.3 0.2 9.3e-06 25.2 0.2 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KXX81053.1 - 0.019 15.2 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases XhlA PF10779.9 KXX81053.1 - 0.18 12.1 0.8 21 5.4 0.0 2.9 2 1 1 3 3 3 0 Haemolysin XhlA Sugar_tr PF00083.24 KXX81054.1 - 1.5e-112 376.8 26.2 2.8e-112 375.9 26.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX81054.1 - 2.9e-25 89.0 62.6 2e-20 73.0 32.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3506 PF12014.8 KXX81056.1 - 6.4e-55 185.0 0.0 5.4e-54 182.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KXX81056.1 - 1.3e-11 44.2 0.9 2.2e-11 43.4 0.9 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX81056.1 - 2.2e-05 24.2 1.6 3.3e-05 23.6 0.3 1.9 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.11 KXX81056.1 - 0.0069 16.9 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 KXX81056.1 - 0.042 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 F-box Oxidored_molyb PF00174.19 KXX81057.1 - 2.2e-57 193.4 0.0 4.3e-57 192.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXX81057.1 - 3.6e-24 85.3 0.1 2.9e-14 53.3 0.1 3.0 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KXX81057.1 - 1.6e-12 47.4 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 KXX81057.1 - 1.9 8.8 3.6 1.2 9.4 0.3 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat UbiA PF01040.18 KXX81058.1 - 1.6e-59 201.3 21.3 1.6e-59 201.3 21.3 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family ZapB PF06005.12 KXX81059.1 - 1.9e-06 28.2 5.2 0.00071 20.0 0.4 3.6 2 1 1 3 3 3 1 Cell division protein ZapB Pox_A_type_inc PF04508.12 KXX81059.1 - 1.3e-05 24.8 2.0 0.00088 19.0 0.0 2.9 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat Syntaxin PF00804.25 KXX81059.1 - 0.00021 21.0 4.8 0.23 11.1 0.2 3.6 3 1 1 4 4 4 1 Syntaxin TSC22 PF01166.18 KXX81059.1 - 0.00023 21.4 0.3 0.12 12.7 0.0 3.0 3 0 0 3 3 2 1 TSC-22/dip/bun family FAM184 PF15665.5 KXX81059.1 - 0.00042 20.2 0.2 0.001 18.9 0.2 1.6 1 1 0 1 1 1 1 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 KXX81059.1 - 0.00088 19.3 5.7 0.0083 16.2 2.1 2.7 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 KXX81059.1 - 0.0033 17.6 5.5 0.56 10.5 1.1 3.2 2 2 1 3 3 3 2 ABC transporter C-terminal domain Ax_dynein_light PF10211.9 KXX81059.1 - 0.0045 17.0 1.3 3.1 7.7 0.0 2.4 2 0 0 2 2 2 2 Axonemal dynein light chain DUF1664 PF07889.12 KXX81059.1 - 0.0047 17.0 3.5 0.15 12.1 0.1 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) DUF16 PF01519.16 KXX81059.1 - 0.0051 17.3 1.8 0.57 10.7 0.2 2.8 2 1 0 3 3 2 1 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.22 KXX81059.1 - 0.0081 16.4 3.1 3.6 7.9 0.1 3.6 2 1 2 4 4 4 1 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 KXX81059.1 - 0.01 16.1 2.3 0.01 16.1 2.3 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 KXX81059.1 - 0.019 13.7 4.2 0.67 8.5 0.2 2.5 2 1 0 2 2 2 0 AAA domain Dynactin_p22 PF07426.11 KXX81059.1 - 0.024 14.5 2.3 0.062 13.2 2.2 1.8 1 1 1 2 2 2 0 Dynactin subunit p22 DUF4795 PF16043.5 KXX81059.1 - 0.026 14.1 2.9 0.11 12.1 2.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 KXX81059.1 - 0.05 12.5 7.6 0.31 9.9 0.4 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 KXX81059.1 - 0.06 12.6 2.1 4.7 6.4 0.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein AIP3 PF03915.13 KXX81059.1 - 0.1 11.6 7.4 0.15 11.1 0.3 2.2 1 1 0 2 2 2 0 Actin interacting protein 3 TMF_DNA_bd PF12329.8 KXX81059.1 - 0.12 12.4 10.1 1.8 8.6 1.3 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding JAKMIP_CC3 PF16034.5 KXX81059.1 - 0.13 12.2 3.3 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 JAKMIP CC3 domain BMFP PF04380.13 KXX81059.1 - 0.16 12.5 3.7 22 5.6 0.4 3.6 3 0 0 3 3 3 0 Membrane fusogenic activity Enkurin PF13864.6 KXX81059.1 - 0.2 12.1 5.1 0.11 12.9 1.5 2.3 2 0 0 2 2 2 0 Calmodulin-binding HalX PF08663.10 KXX81059.1 - 0.28 11.6 2.2 1.5 9.2 0.1 3.1 3 1 1 4 4 2 0 HalX domain Bacillus_HBL PF05791.11 KXX81059.1 - 0.3 10.9 2.8 0.55 10.0 0.7 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GrpE PF01025.19 KXX81059.1 - 0.34 10.6 3.7 1.6 8.4 0.3 2.4 1 1 0 2 2 2 0 GrpE DUF2203 PF09969.9 KXX81059.1 - 0.43 11.3 3.8 15 6.3 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 KXX81059.1 - 0.55 10.5 6.3 6.7 7.1 0.1 3.4 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 KXX81059.1 - 0.6 9.6 5.7 15 5.1 1.1 2.3 1 1 0 1 1 1 0 Intermediate filament protein FlaC_arch PF05377.11 KXX81059.1 - 0.92 9.9 4.0 32 5.0 0.1 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) YlqD PF11068.8 KXX81059.1 - 0.96 9.8 6.5 11 6.5 1.0 2.7 2 1 0 2 2 2 0 YlqD protein ADIP PF11559.8 KXX81059.1 - 1.1 9.3 9.6 4.2 7.4 2.1 3.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 KXX81059.1 - 1.3 9.5 8.7 0.85 10.0 0.3 3.8 3 1 1 4 4 3 0 Csm1 N-terminal domain Hemerythrin PF01814.23 KXX81059.1 - 1.4 9.6 4.1 59 4.3 0.0 3.9 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain Snapin_Pallidin PF14712.6 KXX81059.1 - 1.4 9.4 8.5 1.8 9.0 0.7 2.9 3 0 0 3 3 2 0 Snapin/Pallidin TMF_TATA_bd PF12325.8 KXX81059.1 - 1.5 9.1 6.3 4.5 7.5 0.4 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding YscO PF07321.12 KXX81059.1 - 2 8.4 10.9 2.2 8.2 0.4 3.2 3 1 0 3 3 2 0 Type III secretion protein YscO Uso1_p115_C PF04871.13 KXX81059.1 - 2.2 8.7 4.6 7.5 6.9 0.3 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FAM76 PF16046.5 KXX81059.1 - 3.1 7.1 10.3 0.69 9.2 2.2 2.1 2 0 0 2 2 2 0 FAM76 protein DUF4140 PF13600.6 KXX81059.1 - 4.6 7.7 12.9 1.2 9.6 2.3 3.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) HET PF06985.11 KXX81060.1 - 1.4e-25 90.4 0.0 1e-17 64.8 0.0 2.2 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXX81061.1 - 0.076 13.4 1.1 0.15 12.4 1.1 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) TPR_8 PF13181.6 KXX81061.1 - 0.077 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat APG17 PF04108.12 KXX81062.1 - 0.12 11.5 0.0 4.4 6.3 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 HIP1_clath_bdg PF16515.5 KXX81063.1 - 0.00072 20.1 4.8 0.00072 20.1 4.8 6.9 4 1 3 7 7 7 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 KXX81063.1 - 0.03 14.7 41.1 0.58 10.6 1.8 6.4 4 3 1 5 5 5 0 Cell division protein ZapB YabA PF06156.13 KXX81063.1 - 0.087 13.5 0.5 0.087 13.5 0.5 5.3 4 2 1 5 5 5 0 Initiation control protein YabA ATG16 PF08614.11 KXX81063.1 - 0.098 12.9 56.7 0.23 11.7 3.4 5.4 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) WEMBL PF05701.11 KXX81063.1 - 0.2 10.3 43.2 3.9 6.0 0.0 3.8 3 1 0 3 3 3 0 Weak chloroplast movement under blue light Fez1 PF06818.15 KXX81063.1 - 0.27 11.6 38.9 3.3 8.1 6.3 4.2 2 2 1 3 3 3 0 Fez1 DUF1664 PF07889.12 KXX81063.1 - 0.38 10.8 22.9 0.17 12.0 0.7 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 KXX81063.1 - 0.98 9.8 29.8 1.1 9.7 1.4 5.6 3 1 2 5 5 5 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.11 KXX81063.1 - 1.3 8.8 25.6 1.3 8.8 9.8 4.0 2 1 2 4 4 4 0 Phage minor structural protein GP20 SpoOE-like PF09388.10 KXX81063.1 - 2.4 8.1 5.2 7.2 6.6 0.2 3.2 3 0 0 3 3 2 0 Spo0E like sporulation regulatory protein GAS PF13851.6 KXX81063.1 - 3.3 7.0 40.6 2.1 7.7 5.9 4.8 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 KXX81063.1 - 4.2 6.9 52.8 0.076 12.6 2.0 5.0 2 1 1 4 4 4 0 Mechanosensitive ion channel porin domain GIT_CC PF16559.5 KXX81063.1 - 7.7 6.5 11.6 43 4.1 0.2 4.8 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 KXX81063.1 - 8.8 6.4 43.8 0.056 13.4 1.3 7.3 3 2 2 6 6 6 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KXX81063.1 - 9.1 5.1 47.3 0.92 8.3 6.5 4.3 3 1 1 4 4 4 0 Spc7 kinetochore protein DnaJ PF00226.31 KXX81065.1 - 6.5e-10 39.0 0.3 1.1e-09 38.3 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_6 PF12697.7 KXX81065.1 - 0.036 14.6 3.6 6.4 7.3 0.1 2.6 1 1 2 3 3 3 0 Alpha/beta hydrolase family DEAD PF00270.29 KXX81066.1 - 3.6e-43 147.4 0.0 6.4e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX81066.1 - 8e-28 97.0 0.5 7.6e-27 93.9 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KXX81066.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TFIIA PF03153.13 KXX81066.1 - 0.41 10.6 16.2 0.68 9.9 16.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit API5 PF05918.11 KXX81066.1 - 1.2 7.9 9.1 1.9 7.2 9.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Spt20 PF12090.8 KXX81066.1 - 2.2 7.9 20.4 5.1 6.6 20.4 1.6 1 0 0 1 1 1 0 Spt20 family DUF3328 PF11807.8 KXX81067.1 - 2.7e-27 96.0 8.3 1.8e-26 93.3 7.2 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXX81068.1 - 5.8e-38 130.9 1.0 7e-38 130.6 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NACHT PF05729.12 KXX81069.1 - 4.6e-09 36.4 0.0 5.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 KXX81069.1 - 0.012 14.9 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 KXX81069.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXX81069.1 - 0.024 15.0 0.0 0.029 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KXX81069.1 - 0.028 14.7 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KXX81069.1 - 0.029 14.4 0.0 0.03 14.3 0.0 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 KXX81069.1 - 0.043 13.0 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Bac_DnaA PF00308.18 KXX81069.1 - 0.047 13.5 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein RAG2 PF03089.14 KXX81069.1 - 0.081 11.9 0.0 0.092 11.7 0.0 1.0 1 0 0 1 1 1 0 Recombination activating protein 2 ATPase_2 PF01637.18 KXX81069.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 KXX81069.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase PIF1 PF05970.14 KXX81069.1 - 0.15 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase zf-C2H2_11 PF16622.5 KXX81070.1 - 0.023 14.5 2.8 0.04 13.7 2.8 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 KXX81070.1 - 0.14 12.7 2.1 0.42 11.2 2.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX81070.1 - 2.5 9.2 7.5 0.18 12.7 1.9 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger TAL_FSA PF00923.19 KXX81071.1 - 4.1e-44 151.1 0.0 5e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Lysine_decarbox PF03641.14 KXX81071.1 - 0.045 13.8 0.2 0.09 12.9 0.2 1.5 1 0 0 1 1 1 0 Possible lysine decarboxylase DUF4360 PF14273.6 KXX81073.1 - 6.7e-14 52.2 0.1 7.9e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Abhydrolase_6 PF12697.7 KXX81074.1 - 1.3e-08 35.7 7.8 1.3e-08 35.7 7.8 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX81074.1 - 0.00027 20.7 0.1 0.00052 19.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXX81074.1 - 0.00029 20.7 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.20 KXX81074.1 - 0.0032 17.6 0.1 0.005 17.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KXX81074.1 - 0.0069 15.7 0.2 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KXX81074.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 KXX81074.1 - 0.13 11.9 0.1 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein DUF900 PF05990.12 KXX81074.1 - 0.23 10.9 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cupin_2 PF07883.11 KXX81075.1 - 2.7e-11 43.0 0.3 4.5e-11 42.3 0.3 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXX81075.1 - 0.0024 17.5 0.0 0.0031 17.1 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KXX81075.1 - 0.0036 17.2 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KXX81075.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.14 KXX81075.1 - 0.17 12.1 0.1 0.24 11.5 0.1 1.2 1 0 0 1 1 1 0 ARD/ARD' family Myb_DNA-bind_6 PF13921.6 KXX81077.1 - 2.2e-06 27.8 0.8 2.1e-05 24.7 0.1 2.4 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXX81077.1 - 2.7e-06 27.5 0.9 1e-05 25.6 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KXX81077.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HET PF06985.11 KXX81079.1 - 1.6e-26 93.4 0.2 3.5e-26 92.3 0.2 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VirB3 PF05101.13 KXX81080.1 - 0.0077 16.4 0.8 0.0077 16.4 0.8 2.3 3 0 0 3 3 3 1 Type IV secretory pathway, VirB3-like protein ANAPC4_WD40 PF12894.7 KXX81083.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Amidase PF01425.21 KXX81084.1 - 8e-49 166.8 1.9 2.4e-47 161.9 1.4 2.3 2 1 0 2 2 2 2 Amidase DUF3328 PF11807.8 KXX81085.1 - 2e-41 142.2 5.8 7.2e-40 137.1 5.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acyl_transf_3 PF01757.22 KXX81086.1 - 1.7e-31 109.6 24.2 3.1e-31 108.7 24.2 1.4 1 1 0 1 1 1 1 Acyltransferase family DUF3328 PF11807.8 KXX81089.1 - 2.6e-34 119.0 0.0 2.9e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) VPS9 PF02204.18 KXX81092.1 - 7.7e-25 87.1 0.1 1.4e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXX81092.1 - 0.04 14.2 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) K_oxygenase PF13434.6 KXX81092.1 - 0.23 10.6 0.7 0.65 9.1 0.6 1.7 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) VPS9 PF02204.18 KXX81093.1 - 8e-25 87.1 0.1 1.4e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXX81093.1 - 0.042 14.2 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) K_oxygenase PF13434.6 KXX81093.1 - 0.26 10.4 0.8 0.7 9.0 0.7 1.7 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lipase_3 PF01764.25 KXX81094.1 - 4.6e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KXX81094.1 - 0.03 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 KXX81094.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_C50 PF03568.17 KXX81095.1 - 7e-162 539.1 0.0 1.5e-161 538.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 KXX81095.1 - 0.00097 18.6 0.1 0.053 12.9 0.1 3.2 1 1 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KXX81095.1 - 0.74 10.2 22.4 0.37 11.1 0.4 6.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX81095.1 - 3.5 8.7 21.3 27 5.9 0.1 8.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX81095.1 - 5.1 7.6 9.5 54 4.4 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5321 PF17254.2 KXX81096.1 - 2e-59 199.6 0.0 2.5e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) RAMP4 PF06624.12 KXX81096.1 - 0.048 13.7 0.6 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Qua1 PF16274.5 KXX81096.1 - 0.32 10.9 1.1 0.43 10.4 0.1 1.7 2 0 0 2 2 2 0 Qua1 domain SIR2 PF02146.17 KXX81097.1 - 7.9e-29 100.8 0.0 1.2e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.21 KXX81098.1 - 5.3e-51 173.2 4.7 6.6e-51 172.9 4.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXX81098.1 - 0.0002 21.4 1.7 0.00026 21.1 0.2 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DAPDH_C PF16654.5 KXX81098.1 - 0.019 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain LpxK PF02606.14 KXX81099.1 - 0.087 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase SesA PF17107.5 KXX81100.1 - 0.0073 16.5 0.6 0.015 15.5 0.2 1.7 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases SesA PF17107.5 KXX81101.1 - 1.1e-07 32.1 2.4 1.3e-07 31.9 0.3 2.3 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXX81101.1 - 3e-05 23.5 0.7 7.8e-05 22.1 0.7 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KXX81101.1 - 0.00063 19.7 0.2 0.0014 18.6 0.2 1.6 1 0 0 1 1 1 1 NACHT domain YPEB PF14620.6 KXX81101.1 - 0.06 12.7 1.2 0.1 11.9 0.9 1.4 1 1 0 1 1 1 0 YpeB sporulation AAA_22 PF13401.6 KXX81101.1 - 0.061 13.6 0.0 0.64 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain cwf21 PF08312.12 KXX81101.1 - 0.071 13.3 0.7 0.67 10.1 0.0 2.7 2 0 0 2 2 2 0 cwf21 domain Baculo_PEP_C PF04513.12 KXX81101.1 - 0.38 10.8 1.8 29 4.7 0.1 3.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box_4 PF15966.5 KXX81102.1 - 1.2e-09 38.1 0.1 0.0008 19.3 0.0 2.5 2 0 0 2 2 2 2 F-box F-box-like PF12937.7 KXX81102.1 - 6.8e-09 35.5 0.3 0.0021 17.9 0.0 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KXX81102.1 - 2e-07 30.7 6.5 0.0016 18.3 0.1 3.0 3 0 0 3 3 3 2 F-box domain Sugar_tr PF00083.24 KXX81104.1 - 4e-76 256.7 22.9 5.1e-76 256.4 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX81104.1 - 1.9e-23 83.0 30.7 1.9e-23 83.0 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PLAC8 PF04749.17 KXX81105.1 - 1.2e-20 74.3 11.2 1.5e-20 74.0 11.2 1.1 1 0 0 1 1 1 1 PLAC8 family SH3_3 PF08239.11 KXX81106.1 - 0.0029 17.8 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KXX81106.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain VPS13_C PF16909.5 KXX81107.1 - 0.059 13.1 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal MT0933_antitox PF14013.6 KXX81107.1 - 7.7 6.9 9.7 31 5.0 9.7 2.0 1 1 0 1 1 1 0 MT0933-like antitoxin protein DUF5321 PF17254.2 KXX81109.1 - 2e-59 199.6 0.0 2.5e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) RAMP4 PF06624.12 KXX81109.1 - 0.048 13.7 0.6 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Qua1 PF16274.5 KXX81109.1 - 0.32 10.9 1.1 0.43 10.4 0.1 1.7 2 0 0 2 2 2 0 Qua1 domain CorA PF01544.18 KXX81111.1 - 1.3e-07 31.2 3.9 1.3e-07 31.2 3.9 2.9 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF948 PF06103.11 KXX81111.1 - 0.11 12.8 3.0 2.5 8.4 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LUC7 PF03194.15 KXX81111.1 - 0.41 10.3 7.3 4.3 6.9 0.1 2.8 3 0 0 3 3 3 0 LUC7 N_terminus Rer1 PF03248.13 KXX81112.1 - 1.2e-78 262.8 6.6 1.3e-78 262.6 6.6 1.0 1 0 0 1 1 1 1 Rer1 family ECH_1 PF00378.20 KXX81113.1 - 2.4e-79 266.2 0.1 2.8e-79 266.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX81113.1 - 2.4e-36 125.9 0.2 6.1e-32 111.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HA70_C PF17993.1 KXX81113.1 - 0.17 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain zf-C3HC4_2 PF13923.6 KXX81114.1 - 9.8e-08 31.7 3.0 9.8e-08 31.7 3.0 5.2 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX81114.1 - 1.4e-07 31.3 3.2 1.4e-07 31.3 3.2 6.1 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX81114.1 - 1.6e-07 31.2 1.3 1.6e-07 31.2 1.3 4.7 5 1 0 5 5 5 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXX81114.1 - 1.1e-05 25.7 4.5 1.1e-05 25.7 4.5 5.1 4 1 0 4 4 4 1 Ring finger domain zf-RING_6 PF14835.6 KXX81114.1 - 1.6e-05 24.6 1.0 1.6e-05 24.6 1.0 3.0 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KXX81114.1 - 0.00018 21.6 4.2 0.00018 21.6 4.2 5.6 5 3 0 5 5 5 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.28 KXX81114.1 - 0.00021 20.8 0.0 0.00056 19.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX81114.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXX81114.1 - 0.0092 15.6 0.4 0.078 12.7 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain Rer1 PF03248.13 KXX81115.1 - 1.2e-78 262.8 6.6 1.3e-78 262.6 6.6 1.0 1 0 0 1 1 1 1 Rer1 family ECH_1 PF00378.20 KXX81116.1 - 2.4e-79 266.2 0.1 2.8e-79 266.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXX81116.1 - 2.4e-36 125.9 0.2 6.1e-32 111.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HA70_C PF17993.1 KXX81116.1 - 0.17 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain zf-C3HC4_2 PF13923.6 KXX81117.1 - 9.8e-08 31.7 3.0 9.8e-08 31.7 3.0 5.2 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX81117.1 - 1.4e-07 31.3 3.2 1.4e-07 31.3 3.2 6.1 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX81117.1 - 1.6e-07 31.2 1.3 1.6e-07 31.2 1.3 4.7 5 1 0 5 5 5 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXX81117.1 - 1.1e-05 25.7 4.5 1.1e-05 25.7 4.5 5.1 4 1 0 4 4 4 1 Ring finger domain zf-RING_6 PF14835.6 KXX81117.1 - 1.6e-05 24.6 1.0 1.6e-05 24.6 1.0 3.0 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KXX81117.1 - 0.00018 21.6 4.2 0.00018 21.6 4.2 5.6 5 3 0 5 5 5 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.28 KXX81117.1 - 0.00021 20.8 0.0 0.00056 19.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXX81117.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXX81117.1 - 0.0092 15.6 0.4 0.078 12.7 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain Lipase_3 PF01764.25 KXX81118.1 - 4.6e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KXX81118.1 - 0.03 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 KXX81118.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_C50 PF03568.17 KXX81119.1 - 7e-162 539.1 0.0 1.5e-161 538.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 KXX81119.1 - 0.00097 18.6 0.1 0.053 12.9 0.1 3.2 1 1 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KXX81119.1 - 0.74 10.2 22.4 0.37 11.1 0.4 6.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX81119.1 - 3.5 8.7 21.3 27 5.9 0.1 8.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX81119.1 - 5.1 7.6 9.5 54 4.4 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SIR2 PF02146.17 KXX81120.1 - 7.9e-29 100.8 0.0 1.2e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.21 KXX81121.1 - 5.3e-51 173.2 4.7 6.6e-51 172.9 4.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXX81121.1 - 0.0002 21.4 1.7 0.00026 21.1 0.2 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DAPDH_C PF16654.5 KXX81121.1 - 0.019 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain LpxK PF02606.14 KXX81122.1 - 0.087 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase SesA PF17107.5 KXX81123.1 - 0.0073 16.5 0.6 0.015 15.5 0.2 1.7 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CPDase PF07823.11 KXX81125.1 - 9.7e-33 113.5 0.0 1.4e-32 113.1 0.0 1.2 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KXX81125.1 - 0.013 15.4 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily WD40 PF00400.32 KXX81126.1 - 1.8e-11 44.4 3.9 4.5e-09 36.8 0.4 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81126.1 - 0.0046 17.2 0.1 0.019 15.3 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXX81127.1 - 6.5e-10 39.2 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX81127.1 - 5.8e-07 30.0 1.9 6.5e-07 29.9 0.2 1.9 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 KXX81127.1 - 7e-06 25.6 0.2 1.5e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KXX81127.1 - 0.0052 16.0 0.0 0.009 15.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KXX81127.1 - 0.01 16.4 0.1 0.024 15.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXX81127.1 - 0.021 14.7 0.1 0.061 13.2 0.1 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Rx_N PF18052.1 KXX81127.1 - 0.026 14.8 0.1 0.07 13.4 0.1 1.8 1 1 0 1 1 1 0 Rx N-terminal domain CbiA PF01656.23 KXX81127.1 - 0.032 14.3 1.3 0.29 11.2 0.1 2.8 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KXX81127.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KXX81127.1 - 0.057 12.1 0.4 5.6 5.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 KXX81127.1 - 0.059 13.6 0.7 1.1 9.6 0.0 2.7 2 2 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KXX81127.1 - 0.075 12.3 1.3 0.18 11.0 0.2 1.9 1 1 0 2 2 2 0 KAP family P-loop domain NPV_P10 PF05531.12 KXX81127.1 - 0.081 13.4 0.9 6.2 7.4 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA PF00004.29 KXX81127.1 - 0.11 12.9 0.1 0.61 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXX81127.1 - 0.11 12.8 0.1 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase OmpH PF03938.14 KXX81127.1 - 0.16 12.3 0.4 0.3 11.4 0.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TsaE PF02367.17 KXX81127.1 - 0.17 11.9 0.0 0.69 9.9 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytochrom_B561 PF03188.16 KXX81129.1 - 0.018 15.2 8.4 0.099 12.8 8.7 2.0 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 Adeno_E3 PF06040.11 KXX81129.1 - 0.41 10.8 2.4 13 6.0 0.2 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein DUF4079 PF13301.6 KXX81129.1 - 0.61 10.2 13.4 0.68 10.1 9.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 KXX81129.1 - 1.6 8.3 12.8 7.2 6.2 11.7 2.4 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 WaaY PF06176.11 KXX81130.1 - 0.0066 16.1 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Adaptin_N PF01602.20 KXX81134.1 - 2.8e-101 339.6 0.0 3.6e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXX81134.1 - 7.9e-14 52.0 0.1 5.7e-13 49.2 0.0 2.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXX81134.1 - 2.9e-10 40.4 11.9 1.4e-05 25.4 0.0 5.4 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.22 KXX81134.1 - 7.1e-08 32.1 1.9 0.018 15.3 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat Nop14 PF04147.12 KXX81134.1 - 0.00034 19.0 38.2 0.00051 18.4 38.2 1.2 1 0 0 1 1 1 1 Nop14-like family Cohesin_HEAT PF12765.7 KXX81134.1 - 0.009 16.3 0.1 0.11 12.8 0.0 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KXX81134.1 - 0.009 16.5 9.5 0.45 11.1 0.1 5.1 5 0 0 5 5 5 1 HEAT-like repeat CCSAP PF15748.5 KXX81134.1 - 0.74 9.9 19.7 1.5 8.9 19.7 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4045 PF13254.6 KXX81134.1 - 0.82 9.3 15.0 1.4 8.5 15.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SDA1 PF05285.12 KXX81134.1 - 1.4 8.3 49.6 2.2 7.6 49.6 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KXX81134.1 - 1.6 7.5 17.0 2.3 6.9 17.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nuf2 PF03800.14 KXX81136.1 - 2.4e-42 144.4 0.0 7.6e-42 142.7 0.0 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KXX81136.1 - 4.3e-38 130.0 21.2 4.3e-38 130.0 21.2 4.6 4 1 1 5 5 5 1 Designed helical repeat protein 10 domain P22_AR_C PF10548.9 KXX81136.1 - 0.048 13.8 0.2 19 5.5 0.0 2.6 2 0 0 2 2 2 0 P22AR C-terminal domain UPF0242 PF06785.11 KXX81136.1 - 6.2 6.9 51.5 2.6 8.1 9.7 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus RPA_interact_M PF14767.6 KXX81137.1 - 1.3 9.6 7.0 0.83 10.3 1.3 2.9 2 0 0 2 2 2 0 Replication protein A interacting middle p450 PF00067.22 KXX81139.1 - 6.8e-35 120.7 0.0 8.3e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXX81140.1 - 4.6e-09 35.5 0.0 4.8e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 KXX81141.1 - 3e-08 33.3 0.1 4.5e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXX81141.1 - 0.00025 20.7 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Cupin MFS_1 PF07690.16 KXX81143.1 - 3.4e-47 161.1 42.8 3.4e-47 161.1 42.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX81143.1 - 2.1e-15 56.6 7.5 2.1e-15 56.6 7.5 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KXX81143.1 - 5.8e-09 35.7 6.6 5.8e-09 35.7 6.6 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXX81143.1 - 1.3 7.2 6.4 0.49 8.6 3.2 1.8 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2583 PF10762.9 KXX81143.1 - 2.2 8.8 4.7 1.5 9.3 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) eIF-1a PF01176.19 KXX81144.1 - 2.5e-17 62.4 0.0 3.4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HAD PF12710.7 KXX81145.1 - 2.1e-24 87.0 0.0 2.9e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX81145.1 - 0.00015 22.2 0.3 0.03 14.6 0.0 3.1 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXX81145.1 - 0.00051 19.5 0.0 0.0089 15.5 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.12 KXX81145.1 - 0.00067 19.2 0.0 0.00088 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) UbiA PF01040.18 KXX81146.1 - 1.3e-23 83.6 13.9 1.9e-23 83.1 13.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family NmrA PF05368.13 KXX81147.1 - 1.2e-17 64.3 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX81147.1 - 2.4e-15 56.9 0.0 5.5e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXX81147.1 - 8.9e-07 29.2 0.0 2.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXX81147.1 - 4.5e-06 26.3 0.7 0.00028 20.4 0.1 2.8 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXX81147.1 - 0.00026 20.9 0.1 0.00041 20.3 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXX81147.1 - 0.0026 16.8 0.0 0.0057 15.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KXX81147.1 - 0.0032 17.5 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KXX81147.1 - 0.079 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus LpxI_N PF17930.1 KXX81147.1 - 0.17 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 LpxI N-terminal domain APH PF01636.23 KXX81148.1 - 1.1e-05 25.6 0.0 1.2e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_61 PF03443.14 KXX81149.1 - 1e-48 166.0 0.0 1.3e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DIM PF08194.12 KXX81149.1 - 0.2 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 DIM protein p450 PF00067.22 KXX81150.1 - 1.5e-32 112.9 0.0 1.8e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXX81151.1 - 0.0015 17.4 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 KXX81152.1 - 0.25 11.1 1.4 0.53 10.0 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) p450 PF00067.22 KXX81153.1 - 2.1e-28 99.3 0.0 2.6e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2HE PF16278.5 KXX81154.1 - 1.5e-18 67.0 0.1 3.3e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KXX81154.1 - 9.2e-14 51.9 1.9 1.2e-08 35.4 0.8 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KXX81154.1 - 3.3e-12 47.0 0.4 7.1e-12 45.9 0.4 1.5 1 0 0 1 1 1 1 HIT domain SnoaL_4 PF13577.6 KXX81155.1 - 7.4e-14 52.0 0.1 1.2e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXX81155.1 - 0.0059 17.0 1.0 0.024 15.0 1.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) IBN_N PF03810.19 KXX81156.1 - 4.2e-11 42.6 0.0 1.3e-09 37.8 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 KXX81156.1 - 0.00078 18.1 0.0 0.007 14.9 0.0 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Xpo1 PF08389.12 KXX81156.1 - 0.0015 18.6 0.0 0.053 13.6 0.0 3.3 3 0 0 3 3 3 1 Exportin 1-like protein YccJ PF13993.6 KXX81156.1 - 0.033 14.5 1.4 0.34 11.3 0.5 2.5 2 0 0 2 2 2 0 YccJ-like protein zf-CCHC PF00098.23 KXX81157.1 - 3.3e-05 23.8 0.6 7.1e-05 22.7 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXX81157.1 - 0.0029 17.4 1.3 0.0089 15.8 1.3 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KXX81157.1 - 0.46 10.5 5.9 0.81 9.7 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Metallophos PF00149.28 KXX81158.1 - 1.8e-35 123.3 0.2 2.3e-35 123.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXX81158.1 - 0.041 14.3 0.2 0.1 13.0 0.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Rho_GDI PF02115.17 KXX81159.1 - 2.2e-64 216.8 0.2 2.5e-64 216.6 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.15 KXX81159.1 - 0.0031 17.9 0.0 0.0055 17.1 0.0 1.5 1 1 0 1 1 1 1 ML domain GATase_7 PF13537.6 KXX81160.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain KilA-N PF04383.13 KXX81160.1 - 0.059 13.2 0.0 0.2 11.5 0.0 1.9 1 1 0 1 1 1 0 KilA-N domain NAD_binding_2 PF03446.15 KXX81161.1 - 7.7e-37 126.9 0.0 1.2e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXX81161.1 - 8.5e-31 106.7 0.1 1.9e-30 105.6 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXX81161.1 - 5e-06 27.0 0.0 1.5e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KXX81161.1 - 1.3e-05 24.4 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 KXX81161.1 - 3.4e-05 24.7 0.0 7.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXX81161.1 - 0.0024 18.3 0.0 0.006 17.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXX81161.1 - 0.007 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 KXX81161.1 - 0.0076 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXX81161.1 - 0.036 14.0 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXX81161.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RTA1 PF04479.13 KXX81162.1 - 2.6e-65 219.9 2.8 4.3e-65 219.2 2.8 1.3 1 0 0 1 1 1 1 RTA1 like protein ALG3 PF05208.13 KXX81163.1 - 2.4e-148 494.3 13.0 2.8e-148 494.1 13.0 1.0 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.24 KXX81164.1 - 2e-37 129.6 1.6 2.2e-37 129.4 1.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX81164.1 - 0.00022 20.5 0.0 0.00036 19.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX81164.1 - 0.0007 19.8 0.1 0.0018 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX81164.1 - 0.0015 17.8 0.1 0.0028 16.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX81164.1 - 0.0027 17.0 1.6 0.0052 16.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KXX81164.1 - 0.0049 17.4 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX81164.1 - 0.0069 15.1 0.1 0.0096 14.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KXX81164.1 - 0.073 12.1 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 KXX81164.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Csd3_N PF18059.1 KXX81165.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.5 1 1 1 2 2 2 0 Csd3 N-terminal NPV_P10 PF05531.12 KXX81165.1 - 0.12 12.8 2.2 3.5 8.2 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Thioredoxin PF00085.20 KXX81166.1 - 2.2e-27 95.1 0.2 2.5e-27 94.9 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXX81166.1 - 4.4e-08 33.5 0.2 1.7e-07 31.7 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXX81166.1 - 4e-06 26.4 0.2 4.2e-06 26.3 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXX81166.1 - 1.6e-05 25.1 0.0 0.016 15.6 0.0 2.6 1 1 2 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KXX81166.1 - 0.00011 22.0 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KXX81166.1 - 0.00032 20.4 0.1 0.077 12.7 0.1 2.1 1 1 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 KXX81166.1 - 0.0066 16.4 0.1 0.057 13.4 0.1 1.9 1 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KXX81166.1 - 0.025 14.8 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.6 KXX81166.1 - 0.094 12.4 0.1 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 KXX81166.1 - 0.16 12.2 0.7 0.36 11.1 0.7 1.6 1 1 0 1 1 1 0 Glutaredoxin WSC PF01822.19 KXX81167.1 - 1.1e-19 70.4 7.9 1.8e-19 69.7 7.9 1.4 1 0 0 1 1 1 1 WSC domain Gamma-thionin PF00304.20 KXX81167.1 - 0.038 14.2 0.8 0.13 12.6 0.8 1.9 1 0 0 1 1 1 0 Gamma-thionin family Transferase PF02458.15 KXX81168.1 - 3.5e-19 68.8 0.0 1.2e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 Transferase family COesterase PF00135.28 KXX81169.1 - 6.9e-90 302.3 0.0 3.9e-80 270.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX81169.1 - 4.9e-10 39.6 0.0 8.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Na_Ca_ex PF01699.24 KXX81170.1 - 2.1e-25 89.5 23.0 1.1e-12 48.2 9.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pectate_lyase PF03211.13 KXX81171.1 - 1.9e-85 285.6 10.4 2.8e-85 285.0 10.4 1.2 1 0 0 1 1 1 1 Pectate lyase APH PF01636.23 KXX81172.1 - 5.3e-30 105.1 0.0 9.6e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXX81172.1 - 0.022 13.6 0.0 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KXX81172.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 KXX81172.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Ifi-6-16 PF06140.13 KXX81173.1 - 3.8e-08 33.1 12.4 7e-08 32.3 12.4 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family FAD_binding_3 PF01494.19 KXX81174.1 - 1.6e-20 73.6 0.0 3.4e-20 72.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX81174.1 - 1.5e-08 34.7 2.2 0.0033 17.0 1.6 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX81174.1 - 7.5e-05 22.1 0.3 0.0041 16.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXX81174.1 - 0.0031 16.6 0.0 0.015 14.4 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 KXX81174.1 - 0.011 16.0 0.3 0.029 14.6 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXX81174.1 - 0.047 12.5 3.6 1 8.1 0.1 2.2 1 1 1 2 2 2 0 Tryptophan halogenase NapD PF03927.13 KXX81175.1 - 0.33 11.0 2.8 0.76 9.9 0.2 2.7 3 0 0 3 3 3 0 NapD protein RD3 PF14473.6 KXX81175.1 - 3.1 7.6 7.6 16 5.3 0.1 3.3 3 0 0 3 3 3 0 RD3 protein AAA PF00004.29 KXX81176.1 - 8e-21 74.8 0.5 3e-20 73.0 0.1 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX81176.1 - 0.00022 21.6 3.5 0.00048 20.6 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXX81176.1 - 0.001 19.1 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX81176.1 - 0.0011 19.3 1.6 0.015 15.5 0.1 3.0 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KXX81176.1 - 0.0054 16.5 0.2 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KXX81176.1 - 0.0066 16.5 0.6 0.2 11.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KXX81176.1 - 0.0098 15.6 0.1 0.023 14.4 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXX81176.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXX81176.1 - 0.015 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX81176.1 - 0.028 14.1 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXX81176.1 - 0.029 14.0 0.1 0.078 12.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KXX81176.1 - 0.035 14.2 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 KXX81176.1 - 0.065 12.9 0.2 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KXX81176.1 - 0.066 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXX81176.1 - 0.1 12.9 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXX81176.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KXX81176.1 - 0.16 11.9 0.2 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 KXX81176.1 - 0.18 11.6 1.3 0.94 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF282 PF03380.14 KXX81177.1 - 0.12 12.3 1.9 0.41 10.6 1.0 2.0 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 NAD_binding_4 PF07993.12 KXX81179.1 - 1.7e-21 76.6 0.0 2.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXX81179.1 - 5.6e-07 29.3 0.0 7.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXX81179.1 - 0.024 13.7 0.0 0.043 12.8 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXX81179.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXX81179.1 - 0.12 11.5 0.1 0.28 10.2 0.1 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain TRAM_LAG1_CLN8 PF03798.16 KXX81180.1 - 2.4e-36 125.3 18.3 2.4e-36 125.3 18.3 1.7 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.11 KXX81180.1 - 5.4e-25 86.8 3.2 3.3e-24 84.3 0.1 2.8 2 0 0 2 2 2 1 TRAM1-like protein HORMA PF02301.18 KXX81181.1 - 1.9e-08 34.2 0.0 5.1e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 HORMA domain RhoGEF PF00621.20 KXX81182.1 - 4.8e-27 95.4 1.1 1.1e-26 94.2 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 KXX81182.1 - 0.021 14.6 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Nod1 PF17114.5 KXX81182.1 - 0.029 14.5 0.0 0.12 12.5 0.0 2.2 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 PMC2NT PF08066.12 KXX81182.1 - 3.9 8.2 12.3 5 7.9 0.0 4.6 4 1 1 5 5 5 0 PMC2NT (NUC016) domain DUF3584 PF12128.8 KXX81182.1 - 4 4.8 18.4 0.049 11.2 10.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4404 PF14357.6 KXX81182.1 - 5.3 7.8 8.1 4.9 7.9 2.6 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) YabA PF06156.13 KXX81182.1 - 7 7.4 16.0 4.2 8.0 1.3 4.9 3 1 1 4 4 4 0 Initiation control protein YabA Crystall_3 PF08964.10 KXX81183.1 - 0.0027 17.8 0.5 0.017 15.3 0.3 2.0 1 1 1 2 2 2 2 Beta/Gamma crystallin Pkinase PF00069.25 KXX81184.1 - 7.9e-06 25.4 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81184.1 - 0.014 14.7 0.0 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase HeLo PF14479.6 KXX81184.1 - 0.1 12.4 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation FAD_binding_4 PF01565.23 KXX81185.1 - 2.4e-20 72.7 1.4 5.9e-20 71.4 1.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX81185.1 - 4.5e-10 39.5 0.8 9.5e-10 38.4 0.2 1.9 2 0 0 2 2 2 1 Berberine and berberine like Alpha_kinase PF02816.18 KXX81186.1 - 0.00022 21.4 0.3 0.00044 20.4 0.3 1.5 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KXX81186.1 - 0.0058 17.3 0.1 0.041 14.5 0.0 2.2 1 1 1 2 2 2 1 von Willebrand factor type A domain Ras PF00071.22 KXX81187.1 - 1e-48 165.0 0.0 1.6e-37 128.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXX81187.1 - 4.9e-28 97.8 0.0 2.4e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX81187.1 - 2.9e-08 33.4 0.0 4.5e-07 29.5 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXX81187.1 - 4.2e-05 23.2 0.0 0.00031 20.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX81187.1 - 0.00048 20.2 0.0 0.0039 17.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXX81187.1 - 0.0047 16.3 0.0 0.037 13.4 0.0 2.1 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KXX81187.1 - 0.05 13.9 0.2 0.31 11.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXX81187.1 - 0.079 12.9 0.0 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PMT PF02366.18 KXX81188.1 - 7.5e-83 277.9 16.1 7.5e-83 277.9 16.1 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXX81188.1 - 3.1e-65 219.5 14.6 3.1e-65 219.5 14.6 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXX81188.1 - 1.1e-37 129.7 0.4 1.8e-37 129.0 0.4 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 KXX81188.1 - 0.073 12.9 4.7 0.11 12.3 2.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) WW PF00397.26 KXX81189.1 - 8.5e-11 41.8 6.9 1.6e-10 40.9 6.9 1.5 1 0 0 1 1 1 1 WW domain CtaG_Cox11 PF04442.14 KXX81190.1 - 5.8e-60 201.7 0.0 1e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Amino_oxidase PF01593.24 KXX81191.1 - 3.4e-23 82.6 0.2 9.5e-22 77.9 0.2 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX81191.1 - 7.3e-12 45.3 0.0 1.7e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXX81191.1 - 4.4e-07 30.0 0.1 0.034 14.1 0.0 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KXX81191.1 - 4.3e-05 23.2 0.8 0.00053 19.7 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX81191.1 - 0.0001 21.7 0.0 0.0079 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX81191.1 - 0.0014 17.5 0.0 1.2 7.8 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KXX81191.1 - 0.012 14.8 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX81191.1 - 0.017 15.6 0.1 0.41 11.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXX81191.1 - 0.02 14.2 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Prenylcys_lyase PF07156.14 KXX81191.1 - 0.076 12.1 0.0 0.16 11.1 0.0 1.4 2 0 0 2 2 2 0 Prenylcysteine lyase L51_S25_CI-B8 PF05047.16 KXX81192.1 - 1.5e-19 69.6 0.0 2.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.23 KXX81193.1 - 0.00018 21.6 0.0 0.85 9.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Cys_Met_Meta_PP PF01053.20 KXX81194.1 - 5.5e-153 509.0 0.0 6.2e-153 508.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXX81194.1 - 2.1e-10 40.5 0.2 4.2e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXX81194.1 - 5.5e-10 39.0 0.1 9.1e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXX81194.1 - 4.1e-09 35.9 0.3 6.7e-09 35.2 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXX81194.1 - 9.5e-07 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KXX81194.1 - 3.3e-05 22.6 0.1 4.4e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 KXX81194.1 - 0.0038 17.4 0.1 0.014 15.6 0.0 2.0 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 KXX81194.1 - 0.048 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Ribosomal_60s PF00428.19 KXX81194.1 - 0.28 11.8 7.2 0.55 10.8 1.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2012 PF09430.10 KXX81195.1 - 1.6e-10 41.2 0.0 2.9e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) PUF PF00806.19 KXX81196.1 - 2.3e-37 124.6 0.7 3.5e-06 26.4 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 KXX81196.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 RasGEF domain RraB PF06877.11 KXX81196.1 - 0.13 13.0 0.0 0.36 11.6 0.0 1.7 1 0 0 1 1 1 0 Regulator of ribonuclease activity B MRP-S33 PF08293.11 KXX81197.1 - 2.3e-30 104.7 0.0 2.6e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MutL_C PF08676.11 KXX81197.1 - 0.098 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 MutL C terminal dimerisation domain Aldo_ket_red PF00248.21 KXX81198.1 - 6.1e-43 147.1 0.0 2e-41 142.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 KXX81199.1 - 1.2e-122 410.1 0.0 1.6e-122 409.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family GAPES3 PF17154.4 KXX81200.1 - 0.1 12.5 0.1 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain Molybdopterin PF00384.22 KXX81201.1 - 2.1e-75 254.3 0.0 9e-74 249.0 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KXX81201.1 - 1.8e-20 72.8 0.1 5.5e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KXX81201.1 - 5.2e-18 65.5 0.0 1.5e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KXX81201.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KXX81201.1 - 9.2e-09 35.1 0.4 9.2e-09 35.1 0.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KXX81201.1 - 0.0039 16.9 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KXX81201.1 - 0.12 12.2 1.1 3.5 7.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Ribonuclease_3 PF00636.26 KXX81202.1 - 8.1e-15 55.3 0.0 2.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXX81202.1 - 9.8e-14 51.6 0.0 1.8e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Vsr PF03852.15 KXX81202.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr ACBP PF00887.19 KXX81203.1 - 9e-25 86.7 0.0 1.7e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF5572 PF17733.1 KXX81204.1 - 1.9e-14 53.2 1.9 3.9e-14 52.2 1.9 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DUF3712 PF12505.8 KXX81205.1 - 7e-10 39.2 0.4 9.1e-09 35.6 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXX81205.1 - 0.00029 21.3 0.7 0.27 11.8 0.1 4.2 4 0 0 4 4 4 1 Late embryogenesis abundant protein PapD_C PF02753.17 KXX81205.1 - 0.075 13.4 0.1 0.37 11.2 0.1 2.3 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain EcoEI_R_C PF08463.10 KXX81206.1 - 0.086 13.0 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal DUF1631 PF07793.11 KXX81206.1 - 0.11 11.0 0.6 0.11 10.9 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) LppA PF16708.5 KXX81207.1 - 0.036 14.0 0.4 0.11 12.4 0.1 2.0 2 1 1 3 3 3 0 Lipoprotein confined to pathogenic Mycobacterium GYF PF02213.16 KXX81208.1 - 6.8e-12 44.9 1.0 1.6e-11 43.7 1.0 1.6 1 0 0 1 1 1 1 GYF domain HTH_Tnp_Mu_1 PF02316.16 KXX81208.1 - 0.0079 16.4 0.5 0.017 15.3 0.5 1.6 1 0 0 1 1 1 1 Mu DNA-binding domain Gluconate_2-dh3 PF13618.6 KXX81208.1 - 0.04 14.2 3.4 0.084 13.1 3.4 1.8 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 BT1 PF03092.16 KXX81208.1 - 0.092 11.0 2.6 0.14 10.3 2.6 1.2 1 0 0 1 1 1 0 BT1 family GYF_2 PF14237.6 KXX81208.1 - 0.099 12.5 0.2 0.26 11.1 0.2 1.7 1 0 0 1 1 1 0 GYF domain 2 TIP49 PF06068.13 KXX81209.1 - 2.1e-154 514.0 2.5 2.5e-154 513.7 2.5 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXX81209.1 - 6.6e-22 77.4 0.1 2.2e-21 75.8 0.1 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXX81209.1 - 2.8e-08 34.3 0.3 2.9e-05 24.5 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX81209.1 - 2.8e-08 33.7 0.5 2e-05 24.4 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KXX81209.1 - 6.8e-07 28.9 1.4 1.2e-06 28.0 1.4 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KXX81209.1 - 4.1e-06 27.3 0.1 1.1e-05 25.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KXX81209.1 - 0.0033 16.8 1.0 0.044 13.2 0.5 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXX81209.1 - 0.0059 16.3 0.1 1.4 8.6 0.1 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KXX81209.1 - 0.0077 15.8 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX81209.1 - 0.017 15.1 0.2 2 8.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX81209.1 - 0.025 14.8 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXX81209.1 - 0.03 14.6 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXX81209.1 - 0.035 14.4 2.8 0.7 10.2 2.8 2.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXX81209.1 - 0.042 13.6 1.0 0.2 11.4 1.0 2.0 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXX81209.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KXX81209.1 - 0.1 12.1 0.3 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KXX81209.1 - 0.14 12.4 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NA37 PF04245.13 KXX81209.1 - 0.15 11.5 0.1 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 37-kD nucleoid-associated bacterial protein YrzK PF17449.2 KXX81210.1 - 0.18 12.1 1.3 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized YrzK-like DUF1676 PF07898.13 KXX81210.1 - 0.19 11.8 2.0 0.29 11.2 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Rota_VP2 PF05087.12 KXX81210.1 - 0.64 8.1 2.5 0.84 7.7 2.5 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF2399 PF09664.10 KXX81211.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) DUF1764 PF08576.10 KXX81211.1 - 0.81 10.6 3.4 3.6 8.5 3.4 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TFIIF_alpha PF05793.12 KXX81211.1 - 1.1 7.7 10.8 1.6 7.2 10.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TAF4 PF05236.14 KXX81211.1 - 3.2 7.4 8.4 3.7 7.2 8.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SRP-alpha_N PF04086.13 KXX81211.1 - 7.3 6.4 11.3 9.8 6.0 11.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ORC6 PF05460.13 KXX81211.1 - 9.8 5.3 12.9 3.7e+02 0.2 12.9 2.1 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) F-box-like PF12937.7 KXX81212.1 - 4.7e-05 23.2 0.4 0.00011 22.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KXX81212.1 - 0.021 15.3 6.7 0.24 11.9 0.1 4.3 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) UFD1 PF03152.14 KXX81213.1 - 2e-67 226.0 0.0 2.4e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Choline_transpo PF04515.12 KXX81214.1 - 2.1e-26 92.9 18.7 2.1e-26 92.9 18.7 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF726 PF05277.12 KXX81215.1 - 1.1e-116 389.5 1.7 1.5e-116 389.1 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.15 KXX81216.1 - 2.2e-07 31.1 0.0 8.2e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit WTF PF03303.13 KXX81216.1 - 0.14 11.8 0.9 0.19 11.4 0.9 1.1 1 0 0 1 1 1 0 WTF protein DENN PF02141.21 KXX81217.1 - 8.5e-58 195.4 0.0 1.5e-57 194.6 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KXX81217.1 - 8.3e-15 54.5 0.7 1.9e-14 53.4 0.7 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 KXX81217.1 - 1.8e-13 51.0 0.0 4.9e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.16 KXX81217.1 - 0.0051 17.1 9.0 0.0097 16.2 9.0 1.4 1 0 0 1 1 1 1 C1 domain Collagen PF01391.18 KXX81217.1 - 0.012 15.4 6.4 0.021 14.5 6.4 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) C1_1 PF00130.22 KXX81217.1 - 0.017 15.0 7.6 0.032 14.1 7.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Metaviral_G PF09595.10 KXX81217.1 - 0.017 15.2 9.2 0.021 14.9 1.8 2.6 2 0 0 2 2 2 0 Metaviral_G glycoprotein SPA PF08616.10 KXX81217.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.29 KXX81217.1 - 0.75 9.7 7.5 1.6 8.7 7.5 1.6 1 0 0 1 1 1 0 PHD-finger PPI_Ypi1 PF07491.11 KXX81218.1 - 5.2e-23 80.6 9.3 4.2e-22 77.7 9.3 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.14 KXX81218.1 - 2.4 6.4 7.7 3 6.0 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein KH_1 PF00013.29 KXX81219.1 - 7.9e-11 41.6 0.0 7.6e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 KH domain DUF974 PF06159.13 KXX81220.1 - 4.5e-81 272.3 0.0 5.4e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) OTCace PF00185.24 KXX81221.1 - 2.2e-45 154.6 0.0 3.1e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KXX81221.1 - 1.1e-42 145.6 0.1 1.5e-42 145.1 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ALS_ss_C PF10369.9 KXX81222.1 - 1.3e-15 57.4 0.0 2.9e-14 53.0 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KXX81222.1 - 3.8e-15 55.4 0.1 7.3e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KXX81222.1 - 2.5e-08 33.7 0.0 4.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain OGFr_III PF04680.13 KXX81222.1 - 0.04 14.5 3.0 2 9.2 0.0 2.6 2 0 0 2 2 2 0 Opioid growth factor receptor repeat SNAP PF14938.6 KXX81223.1 - 9.9e-110 366.4 21.2 1.1e-109 366.2 21.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KXX81223.1 - 1.1e-06 28.9 10.3 3.1e-05 24.2 0.8 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX81223.1 - 0.00011 22.0 12.7 1.4 9.2 2.2 6.1 4 1 2 6 6 6 1 Tetratricopeptide repeat SMBP PF16785.5 KXX81223.1 - 0.17 12.1 5.7 0.25 11.6 4.4 1.9 2 1 0 2 2 2 0 Small metal-binding protein Spatacsin_C PF14649.6 KXX81223.1 - 0.27 10.3 7.6 0.47 9.5 1.8 2.6 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_7 PF13176.6 KXX81223.1 - 0.38 10.9 5.9 30 5.0 0.2 4.4 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX81223.1 - 0.58 10.5 20.4 2.1 8.8 1.3 6.4 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX81223.1 - 1.5 8.8 6.2 38 4.3 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX81223.1 - 1.8 9.4 17.0 74 4.3 0.0 6.3 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX81223.1 - 3.6 8.6 12.8 24 6.1 1.5 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat NUC173 PF08161.12 KXX81224.1 - 3.4e-80 268.5 0.0 3.6e-76 255.4 0.0 3.5 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 KXX81224.1 - 0.00057 19.9 0.2 0.57 10.6 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KXX81224.1 - 0.021 15.2 1.4 0.41 11.1 0.3 3.6 3 1 1 4 4 4 0 HEAT repeats Thg1 PF04446.12 KXX81224.1 - 0.031 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase SDA1 PF05285.12 KXX81224.1 - 1.4 8.3 17.9 0.23 10.8 12.4 2.1 2 0 0 2 2 2 0 SDA1 MARVEL PF01284.23 KXX81225.1 - 3.3e-18 66.1 18.5 4e-18 65.8 18.5 1.0 1 0 0 1 1 1 1 Membrane-associating domain AMP-binding PF00501.28 KXX81226.1 - 1.9e-86 290.3 0.0 2.2e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NPP1 PF05630.11 KXX81227.1 - 6.2e-54 183.1 1.3 7.3e-54 182.9 1.3 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Hid1 PF12722.7 KXX81228.1 - 0.73 7.9 5.1 0.93 7.5 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3704 PF12488.8 KXX81231.1 - 0.0028 17.3 0.3 0.0062 16.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3704) Cpn60_TCP1 PF00118.24 KXX81232.1 - 1.5e-87 294.3 11.4 1.5e-86 291.0 11.4 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Baculo_PEP_C PF04513.12 KXX81233.1 - 7.5e-06 26.0 20.6 0.047 13.7 4.6 5.4 2 1 3 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KXX81233.1 - 0.00027 21.0 34.3 0.14 12.2 0.7 6.7 3 2 3 6 6 6 2 Protein of unknown function (DUF1664) APG6_N PF17675.1 KXX81233.1 - 0.0019 18.7 45.2 0.93 10.0 13.5 5.9 2 2 3 6 6 6 3 Apg6 coiled-coil region ATG16 PF08614.11 KXX81233.1 - 0.0024 18.1 21.4 0.0024 18.1 21.4 5.3 2 2 2 5 5 5 2 Autophagy protein 16 (ATG16) Transcrip_act PF04949.13 KXX81233.1 - 0.018 14.9 32.1 0.069 13.0 0.1 4.7 3 2 2 5 5 5 0 Transcriptional activator Filament PF00038.21 KXX81233.1 - 0.05 13.2 49.8 0.054 13.1 32.7 3.7 1 1 1 3 3 3 0 Intermediate filament protein Golgin_A5 PF09787.9 KXX81233.1 - 0.1 12.1 53.8 0.17 11.4 4.5 4.8 1 1 4 5 5 5 0 Golgin subfamily A member 5 WXG100 PF06013.12 KXX81233.1 - 0.11 12.8 17.5 3.1 8.1 0.0 7.2 5 2 2 7 7 6 0 Proteins of 100 residues with WXG DUF948 PF06103.11 KXX81233.1 - 0.17 12.1 24.7 18 5.6 1.9 7.0 4 3 2 6 6 6 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 KXX81233.1 - 0.19 12.0 0.0 0.19 12.0 0.0 6.7 4 3 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 KXX81233.1 - 0.42 9.6 41.3 2.1 7.4 0.2 4.8 2 2 1 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KXX81233.1 - 1.5 7.6 53.8 0.072 12.0 6.7 5.3 2 1 3 6 6 6 0 Spc7 kinetochore protein Prominin PF05478.11 KXX81233.1 - 1.9 6.3 31.6 0.039 11.9 4.2 3.3 1 1 1 3 3 3 0 Prominin Bacillus_HBL PF05791.11 KXX81233.1 - 2 8.2 38.1 0.49 10.2 3.4 6.3 2 2 2 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.12 KXX81233.1 - 2.1 8.4 51.7 0.57 10.3 2.0 6.9 3 1 3 7 7 6 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KXX81233.1 - 2.9 7.2 38.9 0.67 9.3 7.3 3.9 2 1 2 4 4 3 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KXX81233.1 - 3.8 7.5 53.4 0.6 10.1 0.3 6.7 2 2 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SpoOE-like PF09388.10 KXX81233.1 - 4.8 7.2 9.6 30 4.6 1.8 3.8 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Carbpep_Y_N PF05388.11 KXX81233.1 - 5.5 7.6 14.7 14 6.2 2.6 4.1 4 0 0 4 4 4 0 Carboxypeptidase Y pro-peptide AIP3 PF03915.13 KXX81233.1 - 6.5 5.7 43.9 0.8 8.7 22.6 3.5 1 1 1 2 2 1 0 Actin interacting protein 3 Blt1 PF12754.7 KXX81234.1 - 7.9e-35 120.4 0.0 1.1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KXX81234.1 - 5.4e-20 70.7 0.2 9.2e-20 70.0 0.2 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KXX81234.1 - 0.00042 20.0 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Cofilin_ADF PF00241.20 KXX81235.1 - 9.3e-42 141.7 0.3 1e-41 141.5 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein XRCC4 PF06632.12 KXX81236.1 - 1.5e-06 27.3 10.2 3.8e-06 26.0 10.2 1.6 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.8 KXX81236.1 - 0.0032 17.6 3.1 0.0049 17.0 3.1 1.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain DUF3584 PF12128.8 KXX81236.1 - 0.011 13.3 4.7 0.013 13.1 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HalX PF08663.10 KXX81236.1 - 0.42 11.0 7.1 1.5 9.2 7.1 2.0 1 0 0 1 1 1 0 HalX domain CCDC106 PF15794.5 KXX81236.1 - 0.54 9.9 14.5 0.028 14.1 6.8 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 PALP PF00291.25 KXX81238.1 - 1.7e-67 227.9 0.3 2.4e-67 227.4 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KXX81238.1 - 1.3e-12 48.0 0.0 2.1e-08 34.4 0.0 3.4 3 0 0 3 3 3 2 CBS domain FLgD_tudor PF13861.6 KXX81238.1 - 0.14 12.5 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 FlgD Tudor-like domain SRPRB PF09439.10 KXX81239.1 - 3.4e-22 78.7 0.0 6.5e-15 55.0 0.0 3.2 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KXX81239.1 - 8.1e-05 23.1 1.0 0.00027 21.4 0.9 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KXX81239.1 - 0.0028 18.2 0.0 0.0037 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXX81239.1 - 0.0045 17.1 0.0 0.021 14.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXX81239.1 - 0.0056 16.1 0.0 0.52 9.7 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 KXX81239.1 - 0.018 15.5 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KXX81239.1 - 0.025 14.2 0.1 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KXX81239.1 - 0.025 14.8 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXX81239.1 - 0.034 14.1 0.0 0.31 10.9 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase TniB PF05621.11 KXX81239.1 - 0.035 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KXX81239.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX81239.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXX81239.1 - 0.23 11.2 0.1 0.23 11.2 0.1 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain Zn_clus PF00172.18 KXX81240.1 - 6.9e-09 35.7 10.1 1.4e-08 34.7 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX81240.1 - 3.5e-05 23.0 0.0 6.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXX81241.1 - 8.5e-20 71.0 15.1 1.1e-19 70.6 15.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 KXX81243.1 - 0.04 13.9 0.2 0.063 13.3 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PIP5K PF01504.18 KXX81245.1 - 5e-48 163.7 0.0 1.3e-47 162.4 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase UDPG_MGDP_dh_N PF03721.14 KXX81249.1 - 1.7e-50 171.2 0.1 3.5e-35 121.3 0.0 2.6 2 1 1 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXX81249.1 - 6.7e-28 96.7 0.0 1.5e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXX81249.1 - 9.9e-23 80.6 0.0 2e-17 63.5 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 KXX81249.1 - 0.016 15.4 0.2 0.29 11.3 0.2 2.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXX81249.1 - 0.12 12.9 0.1 5 7.8 0.1 3.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KXX81250.1 - 1.2e-19 70.5 0.0 6.3e-16 58.4 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81250.1 - 1.4e-13 51.0 0.1 2.4e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX81250.1 - 0.001 19.0 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KXX81250.1 - 0.039 13.7 0.2 0.078 12.7 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DHHC PF01529.20 KXX81252.1 - 2.2e-33 115.2 11.2 2.2e-33 115.2 11.2 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KXX81252.1 - 1.7e-25 89.4 0.0 2.9e-12 47.0 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX81252.1 - 1.4e-21 76.2 0.0 1.7e-06 28.2 0.0 4.9 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX81252.1 - 5.4e-21 74.7 0.2 1.6e-06 28.6 0.2 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX81252.1 - 1.5e-20 71.1 0.6 4.4e-07 29.7 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KXX81252.1 - 1.7e-19 69.3 0.2 0.00034 20.9 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat lci PF12197.8 KXX81252.1 - 0.15 11.9 0.5 0.36 10.7 0.5 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein PocR PF10114.9 KXX81252.1 - 0.61 9.8 3.1 1.1 9.0 3.1 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR DLH PF01738.18 KXX81253.1 - 7.8e-29 100.8 0.0 9.9e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXX81253.1 - 0.13 11.8 0.0 0.38 10.4 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Gly_transf_sug PF04488.15 KXX81254.1 - 1.3e-10 41.8 0.1 2.7e-10 40.7 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif zf-CCCH PF00642.24 KXX81256.1 - 0.0017 18.2 4.9 0.0017 18.2 4.9 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXX81256.1 - 0.36 10.7 25.4 0.043 13.6 4.0 3.4 3 1 0 3 3 3 0 CCCH-type zinc finger zf-C2H2 PF00096.26 KXX81258.1 - 0.0069 16.8 5.4 0.021 15.3 1.3 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXX81258.1 - 0.014 15.7 2.8 0.02 15.2 1.8 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX81258.1 - 0.03 14.7 5.3 0.051 14.0 1.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3449 PF11931.8 KXX81258.1 - 0.19 11.5 1.2 0.31 10.8 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.6 KXX81258.1 - 0.44 11.5 4.0 0.47 11.4 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Peroxidase_2 PF01328.17 KXX81259.1 - 8.2e-40 137.3 0.0 1e-39 137.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 T2SSK PF03934.13 KXX81259.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K HATPase_c_3 PF13589.6 KXX81259.1 - 0.091 12.6 0.0 0.82 9.5 0.0 2.0 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CcmF_C PF16327.5 KXX81259.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal An_peroxidase PF03098.15 KXX81260.1 - 2.9e-110 369.3 0.0 3.7e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Glyco_hydro_3_C PF01915.22 KXX81261.1 - 3.8e-49 167.4 0.0 6.5e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX81261.1 - 7e-37 127.5 0.0 1.1e-36 126.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXX81261.1 - 9.1e-16 57.7 0.6 2.6e-15 56.3 0.3 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain LSM PF01423.22 KXX81262.1 - 4.2e-17 61.6 0.1 6e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain PspC PF04024.12 KXX81263.1 - 0.2 11.5 1.5 27 4.7 1.4 2.3 2 0 0 2 2 2 0 PspC domain TrbC PF04956.13 KXX81263.1 - 0.56 10.5 4.3 0.35 11.1 1.7 1.8 2 0 0 2 2 2 0 TrbC/VIRB2 family Glyco_hydro_61 PF03443.14 KXX81265.1 - 1.6e-61 207.8 0.0 2.8e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KXX81265.1 - 1.1e-08 34.8 15.1 1.1e-08 34.8 15.1 3.4 3 1 0 3 3 3 1 Fungal cellulose binding domain Flavokinase PF01687.17 KXX81266.1 - 8.6e-10 38.9 0.0 1.6e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase ERG4_ERG24 PF01222.17 KXX81267.1 - 5.9e-176 585.4 1.2 6.7e-176 585.3 1.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXX81267.1 - 0.00066 19.3 0.2 0.0017 17.9 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) SpecificRecomb PF10136.9 KXX81267.1 - 1.4 7.2 2.9 1.9 6.7 2.9 1.1 1 0 0 1 1 1 0 Site-specific recombinase Man-6-P_recep PF02157.15 KXX81268.1 - 5.8e-17 61.6 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KXX81268.1 - 6.1e-14 52.5 0.0 1.5e-13 51.2 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 KXX81268.1 - 3.3e-06 27.2 0.2 0.00013 22.1 0.0 2.3 2 1 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat SDA1 PF05285.12 KXX81268.1 - 0.036 13.5 13.5 0.049 13.1 13.5 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 KXX81268.1 - 0.053 12.5 0.5 0.071 12.1 0.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 KXX81268.1 - 0.074 11.3 11.5 0.1 10.9 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 KXX81268.1 - 0.25 10.5 0.3 0.34 10.1 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 KXX81268.1 - 2.8 6.1 18.9 0.039 12.2 11.5 1.6 2 0 0 2 2 2 0 Nop14-like family YL1 PF05764.13 KXX81268.1 - 3 7.9 20.1 4.5 7.3 20.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Atrophin-1 PF03154.15 KXX81268.1 - 3.6 5.7 6.7 6 5.0 6.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family RNA_pol_Rpc4 PF05132.14 KXX81268.1 - 5.7 7.4 6.5 11 6.4 6.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 KXX81268.1 - 6.5 6.4 5.2 12 5.6 5.2 1.3 1 0 0 1 1 1 0 Connexin RRN3 PF05327.11 KXX81268.1 - 8.4 4.8 15.3 12 4.3 15.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GFA PF04828.14 KXX81269.1 - 0.00052 20.3 1.0 0.00052 20.3 1.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_61 PF03443.14 KXX81270.1 - 5.7e-53 179.9 0.0 7.2e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.11 KXX81271.1 - 3.8e-22 79.2 0.0 6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NicO PF03824.16 KXX81272.1 - 2.5e-68 230.5 4.4 3.4e-68 230.1 4.4 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein TIP39 PF14980.6 KXX81274.1 - 0.018 14.9 0.4 0.041 13.7 0.4 1.6 1 0 0 1 1 1 0 TIP39 peptide Tho2 PF11262.8 KXX81274.1 - 0.84 8.8 3.4 1.4 8.1 3.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Fungal_trans PF04082.18 KXX81275.1 - 4.3e-21 75.1 0.0 7.8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.18 KXX81276.1 - 5.9e-15 55.3 0.1 8.9e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_10 PF00331.20 KXX81276.1 - 0.0057 15.9 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 OmdA PF13376.6 KXX81277.1 - 9.7e-24 83.2 0.6 9.7e-24 83.2 0.6 2.7 4 0 0 4 4 4 1 Bacteriocin-protection, YdeI or OmpD-Associated Peptidase_C12 PF01088.21 KXX81278.1 - 5.9e-42 143.8 0.0 1.1e-24 87.3 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 TGF_beta_GS PF08515.12 KXX81278.1 - 0.3 10.6 0.1 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif PCMT PF01135.19 KXX81280.1 - 6.7e-54 182.8 0.0 7.8e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXX81280.1 - 5e-05 23.1 0.0 7.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXX81280.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81280.1 - 0.00045 20.9 0.0 0.00089 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX81280.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXX81280.1 - 0.026 15.5 0.1 0.057 14.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXX81280.1 - 0.057 14.1 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXX81280.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KXX81280.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) SCP2_2 PF13530.6 KXX81280.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Sterol carrier protein domain OTT_1508_deam PF14441.6 KXX81281.1 - 6e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.23 KXX81281.1 - 0.0027 17.6 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1923 PF09083.10 KXX81281.1 - 0.023 14.4 2.0 0.26 11.0 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1923) DUF2271 PF10029.9 KXX81281.1 - 0.059 13.0 0.3 0.087 12.5 0.3 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Laminin_II PF06009.12 KXX81282.1 - 0.4 10.7 17.8 0.7 9.9 1.0 2.7 2 0 0 2 2 2 0 Laminin Domain II V_ATPase_I PF01496.19 KXX81282.1 - 0.67 7.8 16.6 1.6 6.6 10.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KXX81282.1 - 1.2 8.0 34.1 0.22 10.4 21.5 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein CEP63 PF17045.5 KXX81282.1 - 2.5 7.9 36.5 0.22 11.4 25.3 2.3 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF948 PF06103.11 KXX81282.1 - 3.7 7.9 6.4 13 6.1 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 KXX81282.1 - 4.9 6.1 33.0 0.86 8.6 23.3 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2370 PF10176.9 KXX81284.1 - 1.7e-89 299.3 0.0 2.9e-89 298.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) TMEM252 PF15664.5 KXX81284.1 - 0.042 13.6 0.1 7.8 6.2 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 252 family Mito_carr PF00153.27 KXX81286.1 - 3.3e-50 168.0 4.4 1e-20 73.4 0.3 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein PTR2 PF00854.21 KXX81287.1 - 3.7e-09 35.9 1.2 0.00024 20.1 0.1 2.2 2 0 0 2 2 2 2 POT family DUF4231 PF14015.6 KXX81288.1 - 0.54 10.8 3.7 2 8.9 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) IDO PF01231.18 KXX81291.1 - 1.9e-07 30.3 0.1 2.9e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase HET PF06985.11 KXX81292.1 - 7.2e-23 81.6 0.0 1.4e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COesterase PF00135.28 KXX81293.1 - 1.2e-52 179.5 0.0 2.9e-52 178.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX81293.1 - 3.9e-05 23.6 0.0 8.6e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX81293.1 - 0.0041 16.6 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Zn_clus PF00172.18 KXX81294.1 - 2.5e-07 30.7 13.7 5.7e-07 29.6 13.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX81294.1 - 1.7e-05 23.8 0.9 2.5e-05 23.3 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATX_III PF08098.11 KXX81295.1 - 0.04 13.9 0.5 0.09 12.8 0.5 1.5 1 0 0 1 1 1 0 Anemonia sulcata toxin III family RNA_helicase PF00910.22 KXX81295.1 - 0.21 12.0 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Peroxidase_2 PF01328.17 KXX81297.1 - 3.6e-43 148.3 0.0 4.5e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 BLM10_N PF16547.5 KXX81297.1 - 0.052 13.8 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal LAMTOR PF15454.6 KXX81297.1 - 0.19 12.3 0.2 1 10.0 0.0 2.0 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator E1-E2_ATPase PF00122.20 KXX81298.1 - 8.4e-39 133.0 12.1 8.6e-31 106.9 0.1 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXX81298.1 - 6.6e-25 87.9 6.2 6.6e-25 87.9 6.2 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KXX81298.1 - 4.6e-19 68.3 0.0 9e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX81298.1 - 2e-18 67.5 0.1 6.5e-15 56.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX81298.1 - 1.4e-15 56.8 2.2 1.6e-15 56.5 0.2 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXX81298.1 - 0.0011 18.8 0.2 0.0052 16.6 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PE PF00934.20 KXX81298.1 - 0.14 12.5 0.7 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 PE family Piwi PF02171.17 KXX81299.1 - 5.3e-77 259.0 0.0 8.9e-77 258.3 0.0 1.4 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXX81299.1 - 3.2e-18 66.7 0.1 5.7e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXX81299.1 - 5.5e-13 48.4 0.2 1.4e-12 47.0 0.2 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KXX81299.1 - 2.2e-10 40.7 0.1 9.5e-10 38.7 0.1 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KXX81299.1 - 1.4e-09 37.9 0.0 3.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KXX81299.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute NmrA PF05368.13 KXX81300.1 - 1.2e-12 47.9 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX81300.1 - 2.8e-11 43.7 0.0 5.6e-11 42.7 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXX81300.1 - 8e-08 32.0 0.1 5.6e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXX81300.1 - 0.0039 17.1 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KXX81300.1 - 0.0069 17.0 0.1 0.012 16.1 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 KXX81300.1 - 0.0082 15.3 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXX81300.1 - 0.018 14.2 0.1 0.026 13.6 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXX81300.1 - 0.032 14.5 0.2 0.057 13.7 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXX81300.1 - 0.078 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KXX81300.1 - 0.13 11.2 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXX81300.1 - 0.21 10.9 0.1 0.43 9.9 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KXX81301.1 - 1e-08 34.5 0.0 2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXX81303.1 - 0.00057 20.2 2.0 0.1 13.1 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXX81303.1 - 0.0054 17.1 0.5 0.0054 17.1 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX81303.1 - 0.025 15.4 0.4 0.025 15.4 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KXX81303.1 - 0.23 11.9 0.2 0.23 11.9 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DAO PF01266.24 KXX81304.1 - 9.2e-37 127.4 0.5 1.3e-36 127.0 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 KXX81304.1 - 1.1e-12 47.7 0.1 3e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_oxidored PF12831.7 KXX81304.1 - 4.2e-07 29.7 0.7 0.00076 18.9 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX81304.1 - 3.4e-05 23.2 0.1 8.5e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX81304.1 - 3.8e-05 23.8 0.3 0.0001 22.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX81304.1 - 7.7e-05 21.9 0.3 0.00014 21.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KXX81304.1 - 0.00011 21.6 0.2 0.00019 20.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXX81304.1 - 0.0069 15.7 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX81304.1 - 0.0085 15.2 0.2 0.019 14.1 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KXX81304.1 - 0.01 15.0 0.4 0.046 12.8 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KXX81304.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXX81304.1 - 0.028 13.1 0.2 0.046 12.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KXX81304.1 - 0.058 14.0 0.5 0.17 12.5 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KXX81305.1 - 1.1e-36 126.2 4.1 7.8e-24 84.2 1.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81305.1 - 6.3e-34 117.5 0.2 9e-32 110.5 0.2 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX81305.1 - 3.7e-09 36.7 0.5 3.7e-09 36.7 0.5 2.6 2 1 0 2 2 2 1 KR domain Glu_dehyd_C PF16912.5 KXX81305.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 3Beta_HSD PF01073.19 KXX81305.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXX81305.1 - 0.038 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SET PF00856.28 KXX81306.1 - 7.5e-11 42.7 0.0 1.5e-09 38.5 0.0 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KXX81306.1 - 0.05 14.2 0.0 10 6.9 0.0 2.6 2 0 0 2 2 2 0 SAF domain Cys_Met_Meta_PP PF01053.20 KXX81307.1 - 1.9e-27 95.8 0.0 2.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXX81307.1 - 0.00026 20.3 0.0 0.0005 19.3 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_2 PF00891.18 KXX81308.1 - 7.9e-17 61.3 0.1 3.1e-16 59.3 0.1 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Glyco_transf_20 PF00982.21 KXX81309.1 - 1.2e-149 499.0 0.0 1.7e-149 498.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXX81309.1 - 6.5e-69 231.6 0.0 1.3e-68 230.6 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase DUF3638 PF12340.8 KXX81310.1 - 1.8e-89 299.0 0.2 1.6e-88 295.8 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXX81310.1 - 7.7e-15 54.0 0.1 1.7e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) GFA PF04828.14 KXX81311.1 - 6.8e-11 42.4 1.3 6.8e-11 42.4 1.3 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_11 PF00457.17 KXX81312.1 - 9.8e-68 227.3 10.8 1.1e-67 227.1 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 GFA PF04828.14 KXX81313.1 - 3.7e-15 56.0 0.7 5.8e-15 55.4 0.7 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KXX81313.1 - 0.0005 19.9 0.7 0.0005 19.9 0.7 2.4 3 0 0 3 3 3 1 Nudix N-terminal EI24 PF07264.11 KXX81314.1 - 1.5e-10 41.6 14.0 2.6e-10 40.8 14.0 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF805 PF05656.14 KXX81314.1 - 5.5 7.5 7.1 25 5.3 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Fungal_trans PF04082.18 KXX81315.1 - 1e-13 51.0 0.0 1.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.25 KXX81316.1 - 0.00021 21.5 0.0 0.00029 21.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PFL-like PF02901.15 KXX81317.1 - 0.16 10.5 0.0 0.22 10.1 0.0 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase-like 2-Hacid_dh_C PF02826.19 KXX81318.1 - 9.5e-41 139.1 0.0 5.5e-38 130.1 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXX81318.1 - 0.038 14.5 0.0 0.071 13.6 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 KXX81318.1 - 0.14 12.7 0.0 0.41 11.2 0.0 1.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KXX81319.1 - 0.0077 15.8 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX81319.1 - 0.011 15.9 0.2 0.027 14.7 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX81319.1 - 0.038 13.2 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 KXX81321.1 - 8.4e-23 80.9 55.6 1e-21 77.3 40.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.33 KXX81322.1 - 1e-09 38.0 1.0 1.6e-05 24.6 0.0 3.7 4 0 0 4 4 4 2 F-box domain F-box-like PF12937.7 KXX81322.1 - 1.3e-05 25.0 0.5 0.00075 19.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXX81322.1 - 0.014 15.2 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 F-box LRR_4 PF12799.7 KXX81322.1 - 0.14 12.6 0.0 37 4.9 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Proteasome PF00227.26 KXX81323.1 - 2e-51 174.2 0.1 2.5e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXX81323.1 - 2.3e-11 43.2 0.2 3.6e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 KXX81324.1 - 6.2e-44 148.7 10.0 7e-44 148.5 10.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Chorismate_bind PF00425.18 KXX81325.1 - 4.6e-65 219.8 0.2 1e-36 126.8 0.0 3.1 2 1 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 KXX81325.1 - 2e-21 76.6 0.0 1.3e-13 51.2 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KXX81325.1 - 2.7e-12 47.1 0.0 5.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KXX81325.1 - 1.9e-05 24.6 1.0 0.0074 16.1 0.1 2.4 2 0 0 2 2 2 2 Peptidase C26 TRAPPC9-Trs120 PF08626.11 KXX81326.1 - 0 1379.4 0.0 0 1379.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Longin PF13774.6 KXX81327.1 - 3.7e-24 84.6 0.2 6.7e-24 83.7 0.1 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXX81327.1 - 3e-15 55.8 0.0 5.4e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF5435 PF17503.2 KXX81327.1 - 0.037 13.7 0.2 0.066 12.9 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5435) DUF334 PF03904.13 KXX81327.1 - 0.1 12.2 2.1 8.3 5.9 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF334) DUF1664 PF07889.12 KXX81327.1 - 0.83 9.7 5.8 0.4 10.7 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Anti-TRAP PF15777.5 KXX81328.1 - 0.1 12.6 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein CLPTM1 PF05602.12 KXX81329.1 - 1.9e-157 524.7 0.0 2.3e-157 524.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1772 PF08592.11 KXX81329.1 - 0.73 10.1 3.3 11 6.4 1.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Lysine_decarbox PF03641.14 KXX81330.1 - 1.9e-29 102.5 0.0 2.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXX81330.1 - 3.4e-05 23.5 2.4 0.00031 20.3 2.5 2.1 1 1 0 1 1 1 1 SLOG cluster4 family Glt_symporter PF03616.14 KXX81330.1 - 0.041 12.6 2.4 1.3 7.7 0.3 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter LSDAT_prok PF18171.1 KXX81330.1 - 0.11 11.8 0.4 0.51 9.5 0.1 2.1 1 1 1 2 2 2 0 SLOG in TRPM, prokaryote Elong_Iki1 PF10483.9 KXX81331.1 - 6.2e-76 255.7 0.0 7.6e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 ASXH PF13919.6 KXX81332.1 - 3.4e-36 124.3 0.2 7e-36 123.3 0.2 1.5 1 0 0 1 1 1 1 Asx homology domain YL1_C PF08265.11 KXX81332.1 - 0.071 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Pmp3 PF01679.17 KXX81333.1 - 1.6e-16 60.2 15.4 2.1e-16 59.8 15.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator COX5A PF02284.16 KXX81335.1 - 3.2e-41 139.5 0.2 3.2e-41 139.5 0.2 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va DUF488 PF04343.13 KXX81335.1 - 0.1 13.2 0.2 0.43 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF488 Chromo PF00385.24 KXX81336.1 - 0.001 18.9 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TMF_TATA_bd PF12325.8 KXX81336.1 - 0.9 9.8 31.4 2.2 8.5 7.5 3.9 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 KXX81336.1 - 1.3 9.0 23.3 0.3 11.1 8.3 3.3 1 1 2 3 3 3 0 Laminin Domain II Fzo_mitofusin PF04799.13 KXX81336.1 - 4.4 6.8 19.6 0.95 9.0 4.7 3.1 2 2 1 3 3 3 0 fzo-like conserved region Filament PF00038.21 KXX81336.1 - 5.7 6.4 34.2 3.8 7.0 8.0 3.2 1 1 1 3 3 3 0 Intermediate filament protein DUF2730 PF10805.8 KXX81336.1 - 6.6 6.9 15.2 12 6.0 1.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) YabA PF06156.13 KXX81336.1 - 7 7.4 22.3 8.2 7.1 10.5 3.5 2 1 1 3 3 3 0 Initiation control protein YabA YscO PF07321.12 KXX81336.1 - 9 6.2 40.4 0.63 10.0 17.5 3.5 1 1 2 3 3 3 0 Type III secretion protein YscO Pox_A_type_inc PF04508.12 KXX81336.1 - 9.3 6.3 16.1 1.6 8.7 0.8 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ELO PF01151.18 KXX81338.1 - 1.6e-62 211.3 19.3 1.8e-62 211.1 19.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Glycogen_syn PF05693.13 KXX81339.1 - 0 1181.8 0.0 0 1181.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KXX81339.1 - 4e-05 23.7 0.2 8.8e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KXX81339.1 - 8.4e-05 22.4 0.1 0.00017 21.4 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXX81339.1 - 0.00014 21.5 0.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXX81339.1 - 0.00037 20.9 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXX81339.1 - 0.00099 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain F-box-like PF12937.7 KXX81340.1 - 1.4e-06 28.0 0.3 3.5e-06 26.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KXX81341.1 - 7.9e-70 235.2 0.0 1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81341.1 - 7.7e-35 120.4 0.0 2.2e-34 118.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX81341.1 - 0.0098 15.2 0.1 0.025 13.9 0.0 1.5 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXX81341.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXX81341.1 - 0.029 13.1 0.5 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KXX81341.1 - 0.074 12.0 0.3 0.3 10.0 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain PBP1_TM PF14812.6 KXX81342.1 - 0.042 14.2 6.3 0.073 13.5 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NPR3 PF03666.13 KXX81342.1 - 0.6 8.8 3.3 0.63 8.8 3.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 YqfD PF06898.11 KXX81343.1 - 0.21 10.4 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD MARVEL PF01284.23 KXX81343.1 - 8.7 6.4 11.9 34 4.5 11.9 1.8 1 1 0 1 1 1 0 Membrane-associating domain Pyr_redox_2 PF07992.14 KXX81344.1 - 3.4e-22 79.0 0.0 3.4e-21 75.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX81344.1 - 1.5e-05 25.0 1.3 0.022 14.7 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXX81344.1 - 4.1e-05 22.8 0.5 0.00098 18.3 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 KXX81344.1 - 4.6e-05 22.7 0.5 0.00036 19.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KXX81344.1 - 0.00011 21.5 1.7 0.19 10.8 0.1 2.1 1 1 1 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 KXX81344.1 - 0.00016 21.4 2.5 0.0016 18.1 0.7 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXX81344.1 - 0.00039 19.8 0.1 0.1 11.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX81344.1 - 0.00064 18.5 0.1 0.0039 16.0 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KXX81344.1 - 0.00083 18.5 0.5 0.068 12.2 0.3 2.1 1 1 1 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXX81344.1 - 0.0021 18.2 0.1 0.0044 17.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX81344.1 - 0.048 12.9 0.2 0.21 10.8 0.1 2.1 3 0 0 3 3 3 0 FAD binding domain CorA PF01544.18 KXX81345.1 - 7.2e-10 38.7 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein 7TM-7TMR_HD PF07698.11 KXX81345.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase HET PF06985.11 KXX81346.1 - 1.4e-22 80.7 0.0 2.3e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KXX81347.1 - 9.8e-20 70.8 0.0 2.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81347.1 - 2.3e-16 60.1 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 7TM_GPCR_Srsx PF10320.9 KXX81348.1 - 0.26 10.6 0.9 0.32 10.3 0.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx MFS_1 PF07690.16 KXX81349.1 - 1.6e-12 47.0 24.5 1e-06 28.0 5.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX81349.1 - 0.00016 20.2 1.1 0.00024 19.7 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX81349.1 - 0.0011 17.9 4.3 0.0011 17.9 4.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXX81349.1 - 0.65 8.2 6.3 0.64 8.2 3.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GST_N PF02798.20 KXX81350.1 - 1.8e-11 44.2 0.0 4.1e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX81350.1 - 9.3e-09 35.5 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXX81350.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX81350.1 - 1.6e-08 34.6 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX81350.1 - 6e-08 33.0 0.0 1.7e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX81350.1 - 3.6e-07 30.1 0.0 6.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TfuA PF07812.12 KXX81351.1 - 9.3e-16 57.6 0.0 1.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 TfuA-like protein CHAD PF05235.14 KXX81351.1 - 0.18 11.7 0.2 0.26 11.2 0.2 1.1 1 0 0 1 1 1 0 CHAD domain Cation_efflux PF01545.21 KXX81353.1 - 1.2e-15 57.8 7.1 1.5e-15 57.5 7.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXX81353.1 - 6.3e-12 45.5 0.2 1.3e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4824 PF16106.5 KXX81353.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) EspB PF05802.11 KXX81353.1 - 0.32 11.0 0.1 0.32 11.0 0.1 1.6 2 0 0 2 2 2 0 Enterobacterial EspB protein Glyco_transf_8 PF01501.20 KXX81354.1 - 3.6e-22 79.1 0.3 3.2e-21 76.0 0.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KXX81354.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative RAMP4 PF06624.12 KXX81355.1 - 1.6e-23 82.5 0.1 1.8e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SNRNP27 PF08648.12 KXX81357.1 - 5.2e-28 96.9 0.7 5.2e-28 96.9 0.7 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins SMAP PF15477.6 KXX81358.1 - 1.8e-11 44.8 3.1 1.8e-11 44.8 3.1 4.3 2 1 0 2 2 2 1 Small acidic protein family RFX_DNA_binding PF02257.15 KXX81359.1 - 4.4e-28 97.7 0.1 9.7e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Hydrolase_4 PF12146.8 KXX81360.1 - 1.1e-49 168.9 0.0 1.3e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX81360.1 - 5.6e-13 49.1 0.0 7.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX81360.1 - 7.1e-13 49.7 2.7 8.6e-13 49.4 2.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXX81360.1 - 0.062 12.8 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KXX81360.1 - 0.067 13.1 0.1 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) DLH PF01738.18 KXX81360.1 - 0.12 12.0 0.0 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 KXX81360.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Mid1 PF12929.7 KXX81361.1 - 7.8e-156 519.5 0.1 9.1e-156 519.3 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KXX81361.1 - 8.5e-06 26.4 3.7 0.00042 20.9 1.0 2.5 2 0 0 2 2 2 2 Fz domain TB2_DP1_HVA22 PF03134.19 KXX81362.1 - 8e-29 99.4 8.8 1.3e-28 98.7 8.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bestrophin PF01062.21 KXX81362.1 - 0.03 13.7 0.5 0.042 13.2 0.5 1.3 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Phage_holin_3_6 PF07332.11 KXX81362.1 - 0.42 10.7 2.5 0.71 9.9 2.5 1.5 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III zf-RanBP PF00641.18 KXX81363.1 - 2.4e-18 65.1 13.3 8.4e-11 41.0 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KXX81363.1 - 3.2e-08 33.3 0.0 6.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KXX81363.1 - 1.7e-07 31.9 0.0 2.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_7 PF16367.5 KXX81363.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DUF1281 PF06924.11 KXX81364.1 - 0.014 14.9 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) IL34 PF15036.6 KXX81364.1 - 0.15 12.1 0.1 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Interleukin 34 CAF1C_H4-bd PF12265.8 KXX81365.1 - 4.7e-28 97.2 0.2 3.8e-27 94.3 0.3 2.5 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXX81365.1 - 1.2e-24 86.1 9.6 8e-07 29.7 0.3 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81365.1 - 1.9e-05 24.9 0.1 0.032 14.5 0.0 3.5 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain XRN_N PF03159.18 KXX81366.1 - 2.9e-98 328.1 0.0 5.1e-98 327.3 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KXX81366.1 - 1.3e-72 245.1 2.0 2e-72 244.6 2.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain DsrD PF08679.11 KXX81366.1 - 0.027 14.7 1.5 0.054 13.8 0.4 2.1 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Thioredoxin_14 PF18402.1 KXX81366.1 - 0.089 12.7 0.2 16 5.4 0.2 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain DUF1345 PF07077.11 KXX81366.1 - 0.15 11.7 0.2 0.26 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) XRN1_D1 PF18332.1 KXX81367.1 - 6.7e-78 260.9 0.0 1.1e-77 260.2 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KXX81367.1 - 1.7e-32 111.4 1.0 2.5e-32 110.9 0.0 1.9 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KXX81367.1 - 9.4e-24 83.3 0.3 2.2e-23 82.1 0.3 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN_M PF17846.1 KXX81367.1 - 2.4e-10 40.0 0.0 4.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Xrn1 helical domain Xrn1_D3 PF18194.1 KXX81367.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 TFIIA PF03153.13 KXX81367.1 - 0.11 12.5 6.0 0.16 11.9 6.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KXX81367.1 - 0.78 9.3 10.9 1.4 8.5 10.9 1.3 1 0 0 1 1 1 0 Spt20 family SPC22 PF04573.12 KXX81368.1 - 7.3e-38 129.7 0.1 9.9e-37 126.0 0.1 2.0 1 1 0 1 1 1 1 Signal peptidase subunit Hid1 PF12722.7 KXX81369.1 - 0 1048.8 0.0 0 1048.6 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KXX81369.1 - 1.1e-107 361.0 0.0 1.4e-107 360.7 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein EHN PF06441.12 KXX81370.1 - 6e-25 87.7 0.0 1.1e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus NPCC PF08058.11 KXX81371.1 - 6.8e-24 84.4 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component DUF2417 PF10329.9 KXX81371.1 - 0.17 11.3 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) AMP-binding PF00501.28 KXX81372.1 - 1.8e-18 66.3 0.1 8.6e-09 34.5 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme SurE PF01975.17 KXX81373.1 - 1e-28 100.5 0.3 1.4e-28 100.0 0.3 1.2 1 0 0 1 1 1 1 Survival protein SurE Fungal_trans PF04082.18 KXX81374.1 - 1.4e-05 24.3 0.2 2.4e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX81374.1 - 0.0045 17.1 10.6 0.0071 16.4 0.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_viral_C PF00336.18 KXX81374.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Ctr PF04145.15 KXX81375.1 - 7.3e-40 137.0 0.4 9e-40 136.7 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 KXX81375.1 - 0.2 11.4 5.1 0.72 9.6 4.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YfhO PF09586.10 KXX81375.1 - 1.7 6.8 10.6 0.48 8.6 6.2 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DIT1_PvcA PF05141.12 KXX81376.1 - 1.2e-104 349.7 0.0 1.6e-104 349.3 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.22 KXX81377.1 - 2.1e-53 181.7 0.0 2e-38 132.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 KXX81378.1 - 5.7e-40 137.3 48.7 6.1e-37 127.4 29.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX81378.1 - 6.4e-12 45.1 1.3 6.4e-12 45.1 1.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TTL PF03133.15 KXX81379.1 - 6e-34 117.5 0.0 2.5e-33 115.5 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXX81379.1 - 0.00011 21.6 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KXX81379.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus PHO4 PF01384.20 KXX81380.1 - 3.2e-117 391.3 15.0 3.7e-117 391.1 15.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.16 KXX81381.1 - 1.3e-37 129.5 58.4 3.2e-37 128.3 55.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX81381.1 - 2.2e-07 30.1 10.3 2.2e-07 30.1 10.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1418 PF07214.12 KXX81381.1 - 0.034 14.0 1.8 0.64 9.9 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) Corona_S2 PF01601.16 KXX81381.1 - 1.9 6.9 6.0 0.3 9.5 2.0 1.5 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein DUF2681 PF10883.8 KXX81382.1 - 1.9 9.0 6.4 1.8 9.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SCIMP PF15050.6 KXX81383.1 - 0.0054 17.2 0.1 0.0068 16.9 0.1 1.1 1 0 0 1 1 1 1 SCIMP protein SNARE_assoc PF09335.11 KXX81383.1 - 0.014 15.9 0.3 0.017 15.6 0.3 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein EVC2_like PF12297.8 KXX81383.1 - 0.022 13.4 0.0 0.023 13.4 0.0 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Adeno_E3_CR2 PF02439.15 KXX81383.1 - 0.032 14.0 4.6 0.062 13.1 4.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Comm PF15957.5 KXX81383.1 - 0.059 13.7 0.0 0.061 13.7 0.0 1.1 1 0 0 1 1 1 0 Commissureless Amnionless PF14828.6 KXX81383.1 - 0.07 12.0 0.0 0.072 11.9 0.0 1.0 1 0 0 1 1 1 0 Amnionless MtrF PF09472.10 KXX81383.1 - 0.12 11.8 0.7 0.2 11.1 0.7 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MLANA PF14991.6 KXX81383.1 - 0.14 12.5 0.1 0.14 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein melan-A Fungal_trans_2 PF11951.8 KXX81384.1 - 7.8e-27 94.1 0.8 1.1e-26 93.5 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX81384.1 - 4.3e-07 29.9 8.0 7.8e-07 29.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.20 KXX81385.1 - 4.9e-26 90.7 0.0 6.1e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXX81385.1 - 9.2e-07 29.3 0.1 9.3e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXX81385.1 - 4.7e-06 26.2 0.0 5.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXX81385.1 - 0.0013 18.6 0.1 0.0081 16.1 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXX81385.1 - 0.0041 17.4 0.0 0.033 14.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXX81385.1 - 0.0073 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXX81385.1 - 0.0096 15.7 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KXX81385.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.16 KXX81385.1 - 0.04 13.7 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Spc7 PF08317.11 KXX81387.1 - 8.4e-07 28.2 102.2 0.003 16.5 16.1 6.1 1 1 4 6 6 6 5 Spc7 kinetochore protein Filament PF00038.21 KXX81387.1 - 4.8e-06 26.4 89.8 0.00027 20.6 11.1 3.8 1 1 2 3 3 3 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 KXX81387.1 - 1.9e-05 24.7 97.8 0.00017 21.6 4.7 7.4 1 1 7 8 8 4 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 KXX81387.1 - 0.00081 19.4 4.9 0.00081 19.4 4.9 9.6 3 2 6 10 10 8 2 Designed helical repeat protein 10 domain DUF5082 PF16888.5 KXX81387.1 - 0.0021 18.3 3.2 0.0021 18.3 3.2 8.9 2 2 4 7 7 6 3 Domain of unknown function (DUF5082) Cortex-I_coil PF09304.10 KXX81387.1 - 0.006 16.8 10.7 0.006 16.8 10.7 8.4 2 2 5 8 8 7 2 Cortexillin I, coiled coil CENP-Q PF13094.6 KXX81387.1 - 0.0077 16.5 2.6 0.0077 16.5 2.6 6.9 2 1 5 7 7 4 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF724 PF05266.14 KXX81387.1 - 0.0089 15.9 4.2 0.0089 15.9 4.2 7.5 2 2 6 8 8 8 4 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 KXX81387.1 - 0.0094 16.2 6.1 0.0094 16.2 6.1 10.9 3 2 10 13 13 12 4 ABC transporter C-terminal domain APG6_N PF17675.1 KXX81387.1 - 0.016 15.8 9.1 0.016 15.8 9.1 8.4 1 1 4 6 6 5 0 Apg6 coiled-coil region DUF812 PF05667.11 KXX81387.1 - 0.022 13.7 84.0 0.0074 15.2 13.3 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 KXX81387.1 - 0.059 13.4 39.0 1 9.4 1.8 6.8 4 2 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 KXX81387.1 - 0.15 12.5 87.1 0.032 14.7 11.5 5.5 1 1 3 4 4 4 0 Fez1 Myosin_tail_1 PF01576.19 KXX81387.1 - 0.18 9.5 106.1 0.09 10.6 19.5 3.7 1 1 1 3 3 2 0 Myosin tail DUF1664 PF07889.12 KXX81387.1 - 0.46 10.5 57.5 0.56 10.3 3.5 8.2 2 2 7 10 10 10 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 KXX81387.1 - 0.53 7.7 103.3 0.066 10.7 49.7 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 KXX81387.1 - 0.81 9.6 14.5 1.7 8.6 0.6 6.8 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat TPR_MLP1_2 PF07926.12 KXX81387.1 - 2 8.5 112.7 0.13 12.3 10.6 8.2 2 2 6 8 8 8 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 KXX81387.1 - 2.1 8.3 16.5 9.8 6.1 0.0 6.3 7 1 0 7 7 6 0 Shugoshin N-terminal coiled-coil region BLOC1_2 PF10046.9 KXX81387.1 - 5.7 7.3 54.7 0.074 13.4 0.7 8.3 3 1 6 9 9 9 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APC_N_CC PF16689.5 KXX81387.1 - 7.7 6.7 11.8 3.8 7.7 2.9 4.6 3 2 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain SnoaL_4 PF13577.6 KXX81388.1 - 1.4e-09 38.2 0.0 2.7e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain Arrestin_C PF02752.22 KXX81389.1 - 2.5e-14 53.9 0.0 1.4e-13 51.5 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXX81389.1 - 2.3e-07 31.0 2.5 0.002 18.2 0.0 2.8 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF5621 PF18532.1 KXX81389.1 - 0.11 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) Cyclin PF08613.11 KXX81390.1 - 7.3e-11 42.7 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXX81390.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Fungal_trans PF04082.18 KXX81391.1 - 1.3e-21 76.8 1.7 2.1e-21 76.2 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX81391.1 - 9.2e-08 32.1 11.6 1.8e-07 31.1 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KXX81391.1 - 5.3 7.1 11.8 0.36 10.8 6.2 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Aldo_ket_red PF00248.21 KXX81392.1 - 3.3e-41 141.4 0.0 8.3e-34 117.1 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Abhydrolase_3 PF07859.13 KXX81393.1 - 2.9e-09 37.1 0.0 5.3e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXX81393.1 - 0.0035 16.3 0.0 0.0036 16.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase PAE PF03283.13 KXX81393.1 - 0.014 14.6 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase Peptidase_S9 PF00326.21 KXX81393.1 - 0.029 13.9 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.18 KXX81394.1 - 4.7e-15 55.3 0.1 1.4e-14 53.8 0.0 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 KXX81395.1 - 2.3e-87 293.1 30.6 1.6e-46 159.2 12.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXX81395.1 - 1.1e-68 229.9 0.0 6.7e-33 114.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXX81395.1 - 1.4e-15 57.3 2.6 1.1e-05 24.9 0.0 4.3 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KXX81395.1 - 9.3e-10 38.1 0.2 0.00013 21.4 0.0 3.7 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.6 KXX81395.1 - 5.7e-09 36.4 0.5 0.0013 19.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXX81395.1 - 1.2e-08 34.5 0.4 0.0031 17.2 0.3 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXX81395.1 - 1.6e-07 31.9 2.4 0.0019 18.6 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KXX81395.1 - 1.1e-06 28.7 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXX81395.1 - 1.1e-06 28.6 0.3 0.033 14.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KXX81395.1 - 3.2e-06 26.2 5.1 0.024 13.4 0.0 4.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 KXX81395.1 - 9.9e-05 22.9 0.0 0.7 10.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 KXX81395.1 - 0.00011 22.1 0.6 3.5 7.3 0.0 3.9 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KXX81395.1 - 0.00019 21.2 3.2 0.91 9.2 1.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KXX81395.1 - 0.00039 20.0 1.6 0.42 10.1 0.4 2.7 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 KXX81395.1 - 0.0009 18.5 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 KXX81395.1 - 0.0013 18.9 1.5 3.3 8.0 0.1 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KXX81395.1 - 0.0021 18.0 0.1 1.8 8.6 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KXX81395.1 - 0.0025 17.9 1.8 1.7 8.7 0.5 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain APS_kinase PF01583.20 KXX81395.1 - 0.0041 17.0 0.1 4.4 7.2 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA PF00004.29 KXX81395.1 - 0.0046 17.4 0.2 7.3 7.0 0.0 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 KXX81395.1 - 0.0052 16.5 0.0 0.62 9.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 KXX81395.1 - 0.0069 16.1 0.0 1.9 8.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KXX81395.1 - 0.0072 16.3 0.0 0.049 13.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KXX81395.1 - 0.008 16.4 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KXX81395.1 - 0.013 15.1 0.9 1.3 8.6 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KXX81395.1 - 0.014 15.5 0.0 1.8 8.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KXX81395.1 - 0.015 14.8 0.2 3.3 7.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KXX81395.1 - 0.019 14.1 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase PF06745.13 KXX81395.1 - 0.027 13.8 0.5 1.9 7.7 0.2 2.3 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 KXX81395.1 - 0.028 13.6 0.3 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase3 PF18751.1 KXX81395.1 - 0.03 14.2 0.0 6.8 6.6 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 KXX81395.1 - 0.035 14.2 0.3 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KXX81395.1 - 0.055 14.0 0.0 5.7 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXX81395.1 - 0.18 11.7 0.5 24 4.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KXX81395.1 - 0.19 12.1 0.3 12 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KXX81395.1 - 0.33 11.2 4.0 0.36 11.1 0.0 2.8 4 0 0 4 4 2 0 AAA domain Glyco_hydro_61 PF03443.14 KXX81396.1 - 6.9e-52 176.4 0.0 8.3e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Myb_DNA-binding PF00249.31 KXX81397.1 - 1.1e-37 127.9 10.4 4.1e-16 58.9 0.5 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXX81397.1 - 6.6e-26 90.3 1.2 2.9e-12 46.6 0.3 4.0 3 1 2 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXX81397.1 - 6.2e-05 22.8 0.0 0.059 13.3 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 KXX81397.1 - 0.0093 16.3 4.5 7.1 7.1 0.0 3.6 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 KXX81397.1 - 0.016 15.2 0.0 0.92 9.5 0.0 2.9 2 1 1 3 3 3 0 SLIDE DUF3606 PF12244.8 KXX81397.1 - 0.089 12.7 0.1 0.31 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) MADF_DNA_bdg PF10545.9 KXX81397.1 - 0.12 12.8 0.7 12 6.3 0.0 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 KXX81397.1 - 1.2 9.3 7.3 6.9 6.8 0.7 3.5 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain peroxidase PF00141.23 KXX81398.1 - 2.8e-84 282.4 0.0 1.9e-43 148.8 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 KXX81398.1 - 0.048 13.9 0.0 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX81398.1 - 0.076 13.2 0.0 9.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain 5_nucleotid_C PF02872.18 KXX81399.1 - 3.7e-32 111.7 0.0 6.5e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXX81399.1 - 3.2e-10 40.9 0.7 1.3e-09 38.9 0.2 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KXX81399.1 - 0.039 13.3 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 YmdB-like protein Peptidase_M28 PF04389.17 KXX81400.1 - 9.1e-33 113.6 0.0 1.3e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXX81400.1 - 4.3e-13 49.1 0.2 8.2e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXX81400.1 - 0.00013 21.7 0.0 0.00075 19.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF1667 PF07892.11 KXX81400.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) DUF3938 PF13074.6 KXX81401.1 - 0.026 14.7 3.9 0.081 13.2 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Rhodanese PF00581.20 KXX81402.1 - 7e-24 84.4 0.0 1.6e-10 41.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain adh_short PF00106.25 KXX81404.1 - 6.1e-19 68.2 0.1 1.3e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81404.1 - 1.5e-13 50.9 0.1 5.9e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX81404.1 - 3.5e-06 27.1 0.1 5.4e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX81404.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KXX81405.1 - 1.9e-20 73.1 0.4 3.7e-20 72.1 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX81405.1 - 6.5e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MMS22L_N PF14910.6 KXX81405.1 - 0.2 10.0 0.0 0.3 9.4 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Ank_2 PF12796.7 KXX81406.1 - 2.4e-74 245.9 5.9 1.3e-13 51.4 0.0 8.6 3 1 8 11 11 11 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX81406.1 - 4.8e-57 189.3 4.6 3.4e-08 33.6 0.0 11.2 5 2 7 12 12 12 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX81406.1 - 1.6e-51 172.1 6.1 2.1e-09 37.7 0.0 10.3 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX81406.1 - 6.8e-42 136.6 1.5 0.0011 19.3 0.0 12.7 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 KXX81406.1 - 5.8e-40 134.0 13.2 9.8e-05 22.6 0.0 12.0 13 0 0 13 13 13 8 Ankyrin repeat SPRY PF00622.28 KXX81406.1 - 2.8e-05 24.2 0.2 6.7e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 SPRY domain GATase_7 PF13537.6 KXX81406.1 - 0.026 14.5 0.0 11 6.0 0.0 4.2 4 1 1 5 5 5 0 Glutamine amidotransferase domain DUF2306 PF10067.9 KXX81407.1 - 1.5e-16 60.9 11.9 3.7e-16 59.7 11.9 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) CDH-cyt PF16010.5 KXX81408.1 - 2.1e-50 170.9 3.5 2.4e-50 170.8 3.5 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase YL1_C PF08265.11 KXX81408.1 - 0.17 11.7 1.1 0.39 10.5 0.2 2.0 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Ribosomal_L19e PF01280.20 KXX81409.1 - 1.9e-61 206.4 6.2 1.9e-61 206.4 6.2 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e SHMT PF00464.19 KXX81410.1 - 3.8e-196 651.4 0.0 4.5e-196 651.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KXX81410.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXX81410.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Helicase_C PF00271.31 KXX81411.1 - 6.3e-14 52.3 0.0 1.7e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KXX81411.1 - 6.5e-14 52.1 2.1 8.4e-14 51.8 0.0 2.3 3 0 0 3 3 2 1 Helicase associated domain (HA2) DEAD PF00270.29 KXX81411.1 - 1.1e-10 41.5 0.0 2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXX81411.1 - 1.2e-08 35.3 0.4 1.8e-07 31.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 KXX81411.1 - 1.4e-08 35.0 0.0 3.3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC_tran PF00005.27 KXX81411.1 - 0.01 16.3 0.0 0.035 14.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KXX81411.1 - 0.026 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KXX81411.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 KXX81411.1 - 0.092 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF87 PF01935.17 KXX81411.1 - 0.17 12.0 2.6 63 3.5 0.3 3.5 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 KXX81411.1 - 0.45 11.0 7.9 0.75 10.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain Gcn1_N PF12074.8 KXX81412.1 - 3.3e-119 398.4 3.5 2.3e-118 395.6 0.2 3.9 3 1 1 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KXX81412.1 - 3.6e-37 123.2 35.7 0.012 15.8 0.1 22.9 26 0 0 26 26 22 8 HEAT repeat HEAT_2 PF13646.6 KXX81412.1 - 2e-29 101.8 53.8 2.2e-06 28.0 0.1 15.6 10 4 7 17 17 16 9 HEAT repeats HEAT_EZ PF13513.6 KXX81412.1 - 4.7e-28 97.2 61.7 6.1e-07 29.8 0.0 20.7 16 4 9 25 25 21 6 HEAT-like repeat Cnd1 PF12717.7 KXX81412.1 - 4.5e-18 65.8 8.8 0.18 11.8 0.3 11.4 9 2 2 11 11 11 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXX81412.1 - 5.4e-15 55.8 0.0 0.51 11.0 0.0 10.3 8 3 3 11 11 10 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KXX81412.1 - 2.7e-12 46.7 0.1 0.035 13.7 0.0 6.5 4 1 3 7 7 7 4 CLASP N terminal ParcG PF10274.9 KXX81412.1 - 8.6e-12 45.5 0.9 0.00025 21.2 0.0 5.2 4 1 0 4 4 4 3 Parkin co-regulated protein UME PF08064.13 KXX81412.1 - 3.7e-09 36.4 1.8 5.4 7.0 0.0 9.0 9 1 1 10 10 10 1 UME (NUC010) domain Adaptin_N PF01602.20 KXX81412.1 - 2.1e-08 33.2 13.9 0.0089 14.6 3.2 8.4 4 3 3 7 7 7 1 Adaptin N terminal region MMS19_C PF12460.8 KXX81412.1 - 5.1e-08 32.4 18.8 0.0017 17.5 0.2 7.3 6 1 1 7 7 7 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 KXX81412.1 - 1.8e-06 27.8 0.0 0.0051 16.6 0.0 5.4 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) DUF937 PF06078.11 KXX81412.1 - 8.4e-05 23.2 0.5 6.1 7.5 0.0 5.6 6 0 0 6 6 5 1 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 KXX81412.1 - 0.00015 21.4 1.3 2 7.9 0.0 5.9 5 1 1 6 6 6 1 Tti2 family RIX1 PF08167.12 KXX81412.1 - 0.004 16.9 10.6 0.086 12.6 0.3 5.6 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis TFCD_C PF12612.8 KXX81412.1 - 0.0041 17.0 0.9 0.053 13.3 0.0 3.5 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal RasGEF_N_2 PF14663.6 KXX81412.1 - 0.0043 17.4 0.4 1.2 9.5 0.0 4.8 5 0 0 5 5 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain IFRD PF05004.13 KXX81412.1 - 0.012 14.8 18.2 0.0049 16.0 2.8 6.5 7 1 0 7 7 7 0 Interferon-related developmental regulator (IFRD) FANCI_S2 PF14676.6 KXX81412.1 - 0.024 14.9 0.5 5.6 7.2 0.0 4.6 4 0 0 4 4 4 0 FANCI solenoid 2 Ipi1_N PF12333.8 KXX81412.1 - 0.032 14.8 0.1 1 10.0 0.0 3.6 3 0 0 3 3 2 0 Rix1 complex component involved in 60S ribosome maturation Pes-10 PF07149.11 KXX81412.1 - 0.099 11.7 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Pes-10 Arm PF00514.23 KXX81412.1 - 0.54 10.4 16.3 37 4.5 0.0 8.9 9 1 1 10 10 9 0 Armadillo/beta-catenin-like repeat U3snoRNP10 PF12397.8 KXX81412.1 - 0.62 10.4 14.3 29 5.1 0.1 6.8 7 1 1 8 8 5 0 U3 small nucleolar RNA-associated protein 10 RTP1_C1 PF10363.9 KXX81412.1 - 0.71 10.1 10.8 69 3.7 0.2 8.0 9 1 0 10 10 10 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 KXX81412.1 - 1.4 9.8 23.3 1.1e+02 3.9 0.0 10.8 10 0 0 10 10 9 0 PBS lyase HEAT-like repeat XPC-binding PF09280.11 KXX81412.1 - 3.6 7.4 5.1 19 5.1 0.0 4.6 5 0 0 5 5 4 0 XPC-binding domain SURNod19 PF07712.12 KXX81414.1 - 2e-06 26.8 0.3 3.4e-05 22.8 0.6 2.4 2 1 0 2 2 2 2 Stress up-regulated Nod 19 COX6C PF02937.15 KXX81415.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc COesterase PF00135.28 KXX81416.1 - 5e-68 230.2 0.0 8.3e-68 229.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX81416.1 - 1.9e-08 34.4 1.5 5.9e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXX81416.1 - 0.0037 16.2 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KXX81416.1 - 0.17 11.1 0.1 0.32 10.2 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Hydrolase_6 PF13344.6 KXX81417.1 - 4e-22 78.2 0.0 1.2e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXX81417.1 - 7.1e-13 48.4 0.0 2.2e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXX81417.1 - 0.014 15.7 0.0 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LAL_C2 PF18603.1 KXX81417.1 - 0.091 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 DUF4360 PF14273.6 KXX81419.1 - 2e-41 141.8 0.4 2.4e-41 141.6 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RRM_1 PF00076.22 KXX81420.1 - 7.5e-43 144.2 0.2 3.8e-15 55.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXX81420.1 - 8.3e-32 108.9 0.0 7.3e-24 83.4 0.0 3.6 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXX81420.1 - 2.2e-09 37.1 0.0 0.0031 17.5 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KXX81420.1 - 0.0018 18.1 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 KXX81420.1 - 0.0041 17.1 0.1 0.1 12.6 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif RL PF17797.1 KXX81420.1 - 0.028 14.3 0.0 0.22 11.5 0.0 2.4 3 0 0 3 3 3 0 RL domain Lsm_interact PF05391.11 KXX81420.1 - 0.061 12.8 2.4 0.15 11.6 2.4 1.6 1 0 0 1 1 1 0 Lsm interaction motif PNP_UDP_1 PF01048.20 KXX81422.1 - 1.3e-17 63.8 0.0 3.4e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.32 KXX81422.1 - 3.9e-15 56.0 6.4 1.7e-08 34.9 0.1 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81422.1 - 9.1e-05 22.7 0.2 0.038 14.3 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KXX81422.1 - 0.0018 17.4 0.1 0.39 9.8 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 KXX81422.1 - 0.0079 15.2 0.0 0.017 14.1 0.0 1.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein GMC_oxred_N PF00732.19 KXX81423.1 - 2.3e-59 201.2 0.0 3.4e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX81423.1 - 4e-30 105.2 0.0 7.7e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXX81423.1 - 6.3e-06 26.0 0.0 1.8e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX81423.1 - 0.00014 21.2 0.1 0.076 12.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX81423.1 - 0.00015 21.1 0.1 0.00047 19.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXX81423.1 - 0.00036 20.7 0.0 0.0014 18.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX81423.1 - 0.0013 18.1 0.0 0.38 10.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX81423.1 - 0.0054 15.9 0.1 0.038 13.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXX81423.1 - 0.031 13.3 0.1 0.097 11.7 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXX81423.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KXX81423.1 - 0.13 10.9 0.0 0.27 9.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein RTA1 PF04479.13 KXX81424.1 - 6e-28 97.9 3.9 1.1e-27 97.0 3.9 1.5 1 0 0 1 1 1 1 RTA1 like protein DUF3995 PF13160.6 KXX81424.1 - 0.018 15.4 0.2 0.018 15.4 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) DUF5608 PF18356.1 KXX81424.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5608) Ninjurin PF04923.12 KXX81424.1 - 1.3 9.0 4.6 0.83 9.6 0.8 2.4 2 1 0 2 2 2 0 Ninjurin Glyco_hydro_16 PF00722.21 KXX81425.1 - 2.2e-14 53.3 0.0 3.6e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXX81425.1 - 5.8e-05 21.7 0.1 0.027 12.9 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KXX81425.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Effector_1 PF04518.12 KXX81425.1 - 0.2 10.7 0.1 0.29 10.2 0.1 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Peptidase_S8 PF00082.22 KXX81427.1 - 2.2e-30 106.0 7.9 5e-30 104.8 7.8 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXX81427.1 - 2.7e-10 40.8 0.2 8.4e-10 39.2 0.2 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 Methyltransf_11 PF08241.12 KXX81430.1 - 0.0016 19.0 0.0 0.0028 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF3681 PF12442.8 KXX81430.1 - 0.056 13.9 0.1 0.28 11.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3681) Methyltransf_31 PF13847.6 KXX81430.1 - 0.083 12.7 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_125 PF06824.11 KXX81431.1 - 3.4e-180 599.4 0.0 3.9e-180 599.2 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) zf-CCHC PF00098.23 KXX81433.1 - 1.6e-44 148.1 58.9 1.4e-07 31.3 2.4 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KXX81433.1 - 8.8e-09 35.0 46.2 0.048 13.4 1.3 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KXX81433.1 - 0.00058 19.8 44.9 0.55 10.2 1.5 7.0 4 2 2 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 KXX81433.1 - 0.0087 15.8 46.3 0.019 14.6 1.1 7.0 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger Form_Nir_trans PF01226.17 KXX81434.1 - 0.037 13.4 0.2 0.054 12.8 0.2 1.1 1 0 0 1 1 1 0 Formate/nitrite transporter Apt1 PF10351.9 KXX81434.1 - 0.73 8.6 1.7 0.57 9.0 0.1 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain FAD_binding_3 PF01494.19 KXX81435.1 - 1.1e-16 61.1 0.0 1.6e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXX81435.1 - 4.1e-05 23.3 0.0 0.001 18.7 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXX81435.1 - 0.0008 19.4 0.0 0.0075 16.3 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXX81435.1 - 0.0011 19.2 1.3 0.0033 17.6 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX81435.1 - 0.0012 18.0 0.3 0.011 14.8 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX81435.1 - 0.0023 17.2 0.1 1.1 8.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXX81435.1 - 0.016 14.3 0.0 0.046 12.8 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 KXX81435.1 - 0.023 13.6 0.1 5.1 5.8 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_4 PF01565.23 KXX81436.1 - 7.4e-20 71.1 1.8 1.5e-19 70.1 1.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX81436.1 - 7.9e-07 29.1 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like ORC_WH_C PF18137.1 KXX81438.1 - 1.1 9.4 3.5 2.9 8.0 0.1 2.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal WD40 PF00400.32 KXX81439.1 - 1.6e-40 136.3 3.1 7.4e-08 32.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81439.1 - 3.2e-13 49.8 0.1 0.00061 20.0 0.0 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX81439.1 - 0.044 12.7 0.0 2.6 6.9 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Retro_M PF02813.14 KXX81439.1 - 0.067 13.6 0.0 20 5.6 0.0 3.2 3 0 0 3 3 3 0 Retroviral M domain Nucleoporin_N PF08801.11 KXX81439.1 - 0.07 11.9 0.3 5.8 5.5 0.1 3.1 1 1 0 3 3 3 0 Nup133 N terminal like PD40 PF07676.12 KXX81439.1 - 0.11 12.5 0.2 36 4.5 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KXX81439.1 - 0.12 11.7 0.0 8.6 5.6 0.0 2.7 2 1 1 3 3 3 0 WD40-like domain TRAPP PF04051.16 KXX81440.1 - 2.6e-35 121.3 0.0 3e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KXX81440.1 - 0.039 12.8 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4360 PF14273.6 KXX81441.1 - 6.2e-20 71.8 0.0 6.7e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CFEM PF05730.11 KXX81442.1 - 2.2e-11 43.7 4.4 3.6e-11 43.0 4.4 1.4 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.11 KXX81442.1 - 0.00069 19.7 6.6 0.001 19.2 6.6 1.2 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KXX81442.1 - 0.0041 16.5 0.8 0.0093 15.4 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.6 KXX81442.1 - 0.098 12.9 1.5 0.19 12.0 0.0 2.2 3 0 0 3 3 3 0 Protein melan-A Ndc1_Nup PF09531.10 KXX81442.1 - 0.7 8.5 6.5 0.96 8.1 6.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 KXX81442.1 - 1.7 8.5 6.4 2 8.2 6.4 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KXX81442.1 - 3.6 6.7 13.6 5.1 6.2 13.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein WD40 PF00400.32 KXX81443.1 - 9.6e-45 149.7 23.0 1.1e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81443.1 - 6.8e-09 35.9 0.8 0.13 12.6 0.0 4.6 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX81443.1 - 9.1e-06 24.6 6.4 0.042 12.5 0.1 4.1 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXX81443.1 - 0.0029 16.6 0.0 8.2 5.3 0.0 3.9 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXX81443.1 - 0.0089 15.4 0.0 0.51 9.6 0.0 2.3 2 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KXX81443.1 - 0.018 15.0 0.5 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Bromo_TP PF07524.13 KXX81444.1 - 1e-17 63.9 0.0 1.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 KXX81444.1 - 9.5e-09 35.7 6.4 1.1e-05 25.9 0.7 3.0 3 0 0 3 3 3 2 Transcription factor TFIID complex subunit 8 C-term RAG1 PF12940.7 KXX81444.1 - 0.029 12.4 0.0 0.058 11.5 0.0 1.4 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase CENP-T_C PF15511.6 KXX81444.1 - 0.051 13.7 0.1 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Pkinase_Tyr PF07714.17 KXX81445.1 - 6.6e-11 42.0 0.0 4.3e-09 36.0 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.6 KXX81445.1 - 1.1e-10 41.2 0.0 5.3e-05 22.9 0.0 3.5 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KXX81445.1 - 8e-07 29.3 0.1 1.2 9.7 0.0 4.5 1 1 5 6 6 6 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KXX81445.1 - 2e-06 27.4 0.0 2.1e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXX81445.1 - 4e-05 23.1 0.1 6.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 KXX81445.1 - 0.00026 20.5 0.0 0.00077 19.0 0.0 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KXX81445.1 - 0.026 15.0 1.4 1.5e+02 3.6 0.0 5.0 3 1 0 3 3 3 0 Leucine Rich Repeat 2OG-FeII_Oxy_2 PF13532.6 KXX81446.1 - 1.7e-29 103.4 0.0 4.6e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KXX81446.1 - 3.6e-28 98.9 0.1 2e-27 96.5 0.1 2.1 1 1 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 KXX81446.1 - 0.0018 18.2 0.0 0.0058 16.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L22 PF00237.19 KXX81447.1 - 1.3e-22 79.9 0.4 8.3e-22 77.4 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Exonuc_VII_L PF02601.15 KXX81447.1 - 0.022 14.3 1.7 0.04 13.5 1.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit SH3_4 PF06347.13 KXX81447.1 - 0.034 14.0 0.3 0.093 12.6 0.3 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain DUF3112 PF11309.8 KXX81448.1 - 5e-14 52.3 3.3 1e-08 34.9 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) DUF1418 PF07214.12 KXX81448.1 - 0.067 13.1 4.5 1.5 8.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF420 PF04238.12 KXX81448.1 - 0.74 10.1 11.7 15 5.8 7.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF420) Vut_1 PF02592.15 KXX81448.1 - 8.4 6.7 11.4 0.66 10.3 6.7 1.6 2 0 0 2 2 2 0 Putative vitamin uptake transporter APH PF01636.23 KXX81450.1 - 1.3e-06 28.5 0.5 4.8e-06 26.7 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXX81450.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase MFS_1 PF07690.16 KXX81451.1 - 1.9e-17 63.3 20.3 7.1e-16 58.1 11.0 3.4 3 1 0 3 3 3 2 Major Facilitator Superfamily Adeno_PIX PF03955.14 KXX81453.1 - 0.071 13.3 0.2 0.082 13.1 0.2 1.1 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) TPR_2 PF07719.17 KXX81454.1 - 3.3e-13 48.7 7.0 9.9e-05 22.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXX81454.1 - 5.2e-12 45.0 2.7 0.00053 19.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX81454.1 - 2.5e-07 31.2 2.3 0.00023 21.7 0.6 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXX81454.1 - 2.9e-07 30.1 0.4 0.0065 16.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXX81454.1 - 9.2e-06 25.9 1.8 0.016 15.5 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX81454.1 - 1.9e-05 25.1 0.1 0.014 15.9 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXX81454.1 - 0.0013 18.5 5.4 0.022 14.6 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXX81454.1 - 0.0017 18.8 0.9 0.32 11.7 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX81454.1 - 0.002 18.0 3.4 0.99 9.6 0.1 3.5 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXX81454.1 - 0.0021 18.2 1.8 0.31 11.2 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXX81454.1 - 0.0024 18.1 0.2 0.1 13.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX81454.1 - 0.0032 18.2 2.7 1.1 10.2 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXX81454.1 - 0.011 15.4 1.1 4.4 7.1 0.3 3.4 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 KXX81454.1 - 0.13 12.9 4.2 3.3 8.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXX81454.1 - 0.21 11.7 1.1 5.5 7.1 0.1 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DHR10 PF18595.1 KXX81454.1 - 1.3 9.1 6.9 8 6.6 0.1 2.8 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain TauD PF02668.16 KXX81456.1 - 9.2e-32 110.9 0.0 1.1e-31 110.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXX81456.1 - 0.048 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.16 KXX81457.1 - 3.2e-27 95.4 41.8 3.2e-27 95.4 41.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyltransferase PF01553.21 KXX81458.1 - 1.1e-25 89.8 0.0 1.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXX81458.1 - 2e-13 50.3 0.1 3.5e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus GST_N_2 PF13409.6 KXX81459.1 - 1.1e-05 25.7 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXX81459.1 - 0.0018 18.6 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXX81459.1 - 0.005 17.2 0.0 0.0077 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain p450 PF00067.22 KXX81460.1 - 4.2e-42 144.5 0.0 4.8e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXX81461.1 - 3.6e-23 82.0 0.0 6e-23 81.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KXX81461.1 - 0.0053 15.6 0.1 0.0082 15.0 0.1 1.2 1 0 0 1 1 1 1 Amino acid permease Methyltransf_2 PF00891.18 KXX81462.1 - 7.1e-29 100.6 0.0 3.9e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXX81462.1 - 8.2e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain AAA_33 PF13671.6 KXX81462.1 - 0.029 14.5 1.7 0.049 13.8 0.5 1.9 2 0 0 2 2 2 0 AAA domain Dimerisation PF08100.11 KXX81462.1 - 0.039 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.6 KXX81463.1 - 9e-09 35.4 0.0 3.6e-08 33.4 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81463.1 - 1.9e-07 31.7 0.0 4.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX81463.1 - 1.4e-06 29.0 0.0 2.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX81463.1 - 1.3e-05 25.0 0.0 0.00037 20.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX81463.1 - 0.0001 22.9 0.0 0.00024 21.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KXX81463.1 - 0.0056 16.8 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KXX81463.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MBOAT_2 PF13813.6 KXX81464.1 - 2.6e-19 69.3 4.1 7.1e-19 67.9 4.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 KXX81465.1 - 1.6e-64 218.4 0.0 1.8e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Holin_BhlA PF10960.8 KXX81465.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 BhlA holin family TctB PF07331.11 KXX81465.1 - 0.074 13.3 0.0 0.67 10.2 0.0 2.4 2 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF92 PF01940.16 KXX81465.1 - 0.21 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 Methyltransf_11 PF08241.12 KXX81466.1 - 5.2e-15 55.9 0.1 1.3e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81466.1 - 3.6e-13 50.0 0.1 7.9e-13 48.9 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX81466.1 - 1.6e-11 44.4 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX81466.1 - 9.2e-11 42.4 0.0 1.5e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX81466.1 - 2.2e-09 37.3 0.0 3.7e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX81466.1 - 7.4e-09 35.3 0.0 6.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXX81466.1 - 3.9e-05 23.8 0.0 9.9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KXX81466.1 - 0.00028 20.9 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PepSY_2 PF13670.6 KXX81466.1 - 0.006 16.6 3.8 0.0078 16.2 0.0 2.7 3 0 0 3 3 3 1 Peptidase propeptide and YPEB domain PrmA PF06325.13 KXX81466.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXX81466.1 - 0.074 12.6 0.0 0.75 9.3 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase small domain PCMT PF01135.19 KXX81466.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) P-II PF00543.22 KXX81466.1 - 0.17 12.5 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II Pyr_redox_2 PF07992.14 KXX81467.1 - 1.5e-09 37.5 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX81467.1 - 1.1e-06 28.0 0.0 1.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXX81467.1 - 0.00019 20.6 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KXX81467.1 - 0.00083 18.7 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXX81467.1 - 0.00092 19.4 0.1 0.002 18.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX81467.1 - 0.002 17.8 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXX81467.1 - 0.0027 17.0 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXX81467.1 - 0.0029 16.4 0.0 0.0051 15.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KXX81467.1 - 0.005 16.3 0.1 0.0069 15.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXX81467.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXX81467.1 - 0.034 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXX81467.1 - 0.064 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXX81467.1 - 0.079 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding zf-FPG_IleRS PF06827.14 KXX81468.1 - 0.072 13.0 0.8 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn_ribbon_SprT PF17283.2 KXX81468.1 - 0.16 11.9 3.7 0.63 10.0 2.4 2.5 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Zn_clus PF00172.18 KXX81469.1 - 2.7e-10 40.2 10.0 4.8e-10 39.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX81469.1 - 7.5e-08 31.7 3.5 3.6e-07 29.5 3.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cerato-platanin PF07249.12 KXX81471.1 - 2.5e-56 188.9 3.3 2.9e-56 188.7 3.3 1.0 1 0 0 1 1 1 1 Cerato-platanin Ribonuclease_T2 PF00445.18 KXX81472.1 - 3.4e-35 121.9 0.0 4.4e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family ADH_zinc_N_2 PF13602.6 KXX81472.1 - 0.06 14.4 0.0 0.1 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 4HBT_2 PF13279.6 KXX81473.1 - 3.7e-23 82.3 0.0 5.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXX81473.1 - 0.054 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily DUF4720 PF15846.5 KXX81473.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) DUF1664 PF07889.12 KXX81474.1 - 0.35 10.9 12.5 0.41 10.7 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KXX81474.1 - 1.5 7.3 14.0 2.5 6.6 14.0 1.4 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.22 KXX81474.1 - 2.1 8.6 24.7 1.2 9.4 3.5 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain UCH_C PF18031.1 KXX81474.1 - 4.1 7.4 6.8 0.32 10.9 1.3 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases DUF4407 PF14362.6 KXX81474.1 - 5 6.4 29.4 2.1e+03 -2.3 29.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Exo_endo_phos PF03372.23 KXX81475.1 - 1.3e-18 67.4 0.7 1e-17 64.4 0.7 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KXX81475.1 - 4.6e-07 30.0 4.9 0.00013 22.3 3.0 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXX81475.1 - 5.3e-06 26.1 8.6 0.00055 19.6 0.1 2.6 2 1 1 3 3 3 2 Leucine rich repeat Methyltransf_25 PF13649.6 KXX81476.1 - 3.2e-11 43.8 0.0 1.1e-09 38.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX81476.1 - 6.3e-08 33.2 0.0 5.8e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX81476.1 - 3.9e-07 30.0 0.0 7.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX81476.1 - 4.5e-06 26.5 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXX81476.1 - 0.0048 16.3 0.0 0.067 12.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXX81476.1 - 0.011 16.4 0.0 0.28 12.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain CFEM PF05730.11 KXX81477.1 - 2.7e-10 40.2 9.4 3.9e-10 39.7 9.4 1.2 1 0 0 1 1 1 1 CFEM domain NAD_kinase PF01513.21 KXX81478.1 - 9.7e-49 166.1 0.0 6.9e-48 163.3 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KXX81478.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Methyltransf_11 PF08241.12 KXX81479.1 - 1.9e-11 44.4 0.0 3.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81479.1 - 1.1e-10 42.1 0.0 2.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX81479.1 - 0.0081 16.9 0.0 0.013 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX81479.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NmrA PF05368.13 KXX81480.1 - 1.9e-25 89.8 1.0 2.4e-25 89.4 1.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX81480.1 - 8.7e-20 71.4 0.5 2.9e-19 69.7 0.1 2.0 3 0 0 3 3 3 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXX81480.1 - 0.00028 21.2 0.1 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXX81480.1 - 0.011 15.2 0.0 4.2 6.8 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF2913 PF11140.8 KXX81480.1 - 0.11 12.2 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) TauD PF02668.16 KXX81481.1 - 8e-37 127.5 0.0 1e-36 127.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXX81481.1 - 0.0012 18.0 0.1 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 CsiD FR47 PF08445.10 KXX81484.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Virul_fac_BrkB PF03631.15 KXX81485.1 - 0.00023 20.9 2.7 0.00023 20.9 2.7 1.7 2 0 0 2 2 2 1 Virulence factor BrkB Methyltransf_23 PF13489.6 KXX81487.1 - 3.9e-06 26.8 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81487.1 - 0.024 15.3 0.0 0.1 13.3 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain SRP54_N PF02881.19 KXX81487.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain KicB PF03882.14 KXX81487.1 - 0.2 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 MukF winged-helix domain Pyr_redox_2 PF07992.14 KXX81488.1 - 4e-20 72.2 0.5 8.8e-19 67.8 0.5 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX81488.1 - 2.3e-07 30.3 0.0 5.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX81488.1 - 4.4e-06 26.5 3.5 9e-05 22.2 1.0 2.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX81488.1 - 6.8e-06 25.0 0.0 0.0001 21.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXX81488.1 - 9e-06 25.0 0.5 0.0012 18.0 0.6 2.2 1 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXX81488.1 - 1.6e-05 24.3 0.1 0.00011 21.5 0.0 2.2 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX81488.1 - 4.6e-05 23.6 0.4 0.00013 22.2 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXX81488.1 - 6.1e-05 22.4 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXX81488.1 - 0.00011 22.3 0.7 0.48 10.4 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXX81488.1 - 0.00081 18.8 0.7 0.0013 18.1 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX81488.1 - 0.00082 18.7 0.1 0.0021 17.4 0.1 1.7 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXX81488.1 - 0.0027 16.8 0.4 0.024 13.7 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXX81488.1 - 0.0028 18.1 0.2 0.17 12.3 0.0 2.5 3 0 0 3 3 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KXX81488.1 - 0.0099 15.2 0.0 0.0099 15.2 0.0 2.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KXX81488.1 - 0.022 13.6 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Glyco_transf_4 PF13439.6 KXX81488.1 - 0.045 13.8 0.3 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Acyltransferase PF01553.21 KXX81489.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 Acyltransferase Kinesin PF00225.23 KXX81490.1 - 1.5e-104 349.6 0.3 1.5e-104 349.6 0.3 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXX81490.1 - 5.7e-54 182.1 1.0 1e-53 181.3 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding WEMBL PF05701.11 KXX81490.1 - 0.00012 20.9 38.4 0.00012 20.9 38.4 1.8 2 0 0 2 2 2 1 Weak chloroplast movement under blue light MiaE_2 PF13794.6 KXX81490.1 - 0.0085 15.8 1.4 0.017 14.9 1.4 1.5 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like AAA_16 PF13191.6 KXX81490.1 - 0.041 14.3 0.0 0.041 14.3 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KXX81490.1 - 0.06 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXX81490.1 - 0.72 10.1 0.0 0.72 10.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Mce4_CUP1 PF11887.8 KXX81490.1 - 0.82 9.1 3.3 1.4 8.3 2.3 1.9 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative CLP_protease PF00574.23 KXX81491.1 - 5.3e-70 235.0 0.1 6.9e-70 234.6 0.1 1.1 1 0 0 1 1 1 1 Clp protease MWFE PF15879.5 KXX81491.1 - 0.16 12.1 0.1 0.33 11.1 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit ILVD_EDD PF00920.21 KXX81492.1 - 5e-213 708.4 0.1 5.8e-213 708.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family DNA_primase_lrg PF04104.14 KXX81493.1 - 1.4e-83 280.3 0.0 2.4e-83 279.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Thioesterase PF00975.20 KXX81495.1 - 2.6e-10 40.8 0.0 7.3e-10 39.3 0.0 1.7 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXX81495.1 - 1.6e-07 32.2 0.0 2.8e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX81495.1 - 0.0031 17.3 0.1 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PS_Dcarbxylase PF02666.15 KXX81496.1 - 8.3e-56 188.7 0.1 1e-55 188.4 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase FAD_binding_3 PF01494.19 KXX81498.1 - 2e-72 244.4 0.0 5e-72 243.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX81498.1 - 2.9e-06 26.7 0.2 0.047 12.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX81498.1 - 0.00023 20.9 2.0 0.0047 16.6 0.4 3.0 1 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX81498.1 - 0.0011 18.1 0.1 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KXX81498.1 - 0.0027 17.0 0.0 0.074 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX81498.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KXX81498.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 KXX81498.1 - 0.06 13.9 0.1 1.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXX81498.1 - 0.095 13.0 0.1 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 KXX81498.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KXX81498.1 - 0.11 11.5 0.1 0.41 9.6 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXX81498.1 - 0.12 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family CAP PF00188.26 KXX81500.1 - 9.4e-16 58.8 0.9 2e-15 57.8 0.9 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Complex1_LYR PF05347.15 KXX81501.1 - 5.5e-05 23.1 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) UQ_con PF00179.26 KXX81502.1 - 4.5e-13 49.1 0.1 7.1e-13 48.4 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXX81502.1 - 0.0062 16.8 0.0 0.0068 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain E1_4HB PF16191.5 KXX81502.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Pkinase PF00069.25 KXX81503.1 - 1.1e-33 116.7 0.0 9.1e-25 87.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81503.1 - 2.6e-23 82.7 0.0 4.3e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-F_N PF10481.9 KXX81503.1 - 0.0065 16.1 1.7 0.0065 16.1 1.7 1.9 2 0 0 2 2 2 1 Cenp-F N-terminal domain Kdo PF06293.14 KXX81503.1 - 0.028 13.8 0.1 0.028 13.8 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Flu_PB2 PF00604.17 KXX81503.1 - 0.077 10.9 1.5 0.11 10.4 1.5 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 Rabaptin PF03528.15 KXX81503.1 - 0.1 11.3 3.3 0.15 10.8 3.3 1.2 1 0 0 1 1 1 0 Rabaptin GBP_C PF02841.14 KXX81503.1 - 0.22 10.9 2.8 0.35 10.2 2.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain APH PF01636.23 KXX81503.1 - 0.8 9.6 3.7 0.47 10.3 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Golgin_A5 PF09787.9 KXX81503.1 - 0.84 9.0 7.0 1.4 8.3 7.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fungal_TACC PF12709.7 KXX81503.1 - 1.1 9.8 3.2 2.1 8.9 2.9 1.6 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins betaPIX_CC PF16523.5 KXX81503.1 - 3 7.7 6.9 8 6.4 6.9 1.7 1 1 0 1 1 1 0 betaPIX coiled coil DivIC PF04977.15 KXX81503.1 - 3.1 7.6 7.7 4.2 7.2 6.4 1.8 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 KXX81504.1 - 2.3e-07 30.8 1.4 4.4e-07 29.9 1.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor PilO PF04350.13 KXX81504.1 - 0.042 14.0 0.2 0.073 13.2 0.2 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO bZIP_2 PF07716.15 KXX81504.1 - 0.13 12.3 4.4 0.47 10.6 3.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF1938 PF09153.10 KXX81504.1 - 0.25 11.5 0.0 19 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) Methyltransf_31 PF13847.6 KXX81505.1 - 4.9e-25 88.1 0.0 6.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81505.1 - 3.6e-17 62.8 0.0 6.5e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX81505.1 - 9.2e-16 58.3 0.0 1.8e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX81505.1 - 1.4e-12 47.4 0.0 2.3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXX81505.1 - 8.3e-09 36.1 0.0 1.3e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX81505.1 - 8.7e-09 35.4 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXX81505.1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 KXX81505.1 - 9.4e-05 22.2 0.0 0.00014 21.7 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXX81505.1 - 0.00018 21.0 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KXX81505.1 - 0.0032 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KXX81505.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.20 KXX81505.1 - 0.041 13.2 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KXX81505.1 - 0.045 13.8 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KXX81505.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 KXX81505.1 - 0.23 10.7 0.1 0.51 9.6 0.1 1.5 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_9 PF08003.11 KXX81505.1 - 0.28 10.1 0.0 0.98 8.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) BLM10_mid PF16507.5 KXX81506.1 - 3.9e-205 682.5 0.0 7e-205 681.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KXX81506.1 - 1e-29 102.2 0.0 1.7e-28 98.4 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KXX81506.1 - 7.9e-23 80.5 0.1 3.9e-22 78.3 0.0 2.3 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 KXX81506.1 - 0.83 10.1 7.4 25 5.5 0.1 5.5 6 0 0 6 6 6 0 HEAT repeat Glyoxalase PF00903.25 KXX81507.1 - 2e-08 34.5 0.1 2.4e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CENP-F_leu_zip PF10473.9 KXX81508.1 - 0.065 13.3 0.4 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KXX81508.1 - 0.077 13.3 0.8 0.19 12.0 0.8 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 KXX81508.1 - 0.089 12.9 0.4 0.17 12.0 0.4 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1192 PF06698.11 KXX81508.1 - 0.14 12.3 2.1 0.52 10.4 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Tektin PF03148.14 KXX81508.1 - 0.17 10.6 0.3 0.26 10.0 0.3 1.2 1 0 0 1 1 1 0 Tektin family ATG16 PF08614.11 KXX81508.1 - 0.57 10.4 3.5 0.63 10.2 1.8 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 KXX81508.1 - 0.68 8.4 4.7 0.84 8.1 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CHAT PF12770.7 KXX81509.1 - 3.8e-29 102.0 0.0 8.4e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.17 KXX81509.1 - 6.8e-09 35.3 0.0 1.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 TPR_19 PF14559.6 KXX81509.1 - 7.6e-06 26.3 0.7 6.2 7.4 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KXX81509.1 - 0.022 14.8 0.2 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_14 PF13428.6 KXX81509.1 - 0.071 14.0 10.9 14 6.9 0.0 6.6 6 2 1 7 7 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KXX81509.1 - 0.47 10.5 3.7 1.6 8.8 0.1 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 KXX81509.1 - 2.8 8.2 4.8 84 3.5 0.0 5.0 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 S1FA PF04689.13 KXX81510.1 - 0.14 12.3 1.8 0.35 11.1 0.5 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA Yip1 PF04893.17 KXX81510.1 - 2.8 7.6 15.5 0.12 12.0 0.3 3.9 4 0 0 4 4 4 0 Yip1 domain AAA PF00004.29 KXX81511.1 - 0.00063 20.2 0.0 0.0027 18.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CorA PF01544.18 KXX81511.1 - 0.043 13.1 3.1 0.092 12.1 1.2 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein AAA_5 PF07728.14 KXX81511.1 - 0.049 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXX81511.1 - 0.062 13.7 0.0 0.85 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain PGG PF13962.6 KXX81511.1 - 0.075 12.8 0.3 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function Peptidase_M13_N PF05649.13 KXX81511.1 - 0.093 12.4 0.6 7.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M13 DUF746 PF05344.11 KXX81511.1 - 0.1 12.4 0.0 0.96 9.3 0.0 2.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) RuvB_N PF05496.12 KXX81511.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain GMC_oxred_N PF00732.19 KXX81512.1 - 1.3e-55 188.9 0.0 1.8e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX81512.1 - 5.5e-39 134.0 0.0 1e-38 133.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXX81512.1 - 0.00025 20.2 0.1 0.00039 19.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXX81512.1 - 0.00077 18.8 0.1 0.0081 15.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX81512.1 - 0.0027 17.3 0.8 0.012 15.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX81512.1 - 0.021 15.0 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX81512.1 - 0.031 13.3 0.4 0.52 9.3 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 KXX81512.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KXX81512.1 - 0.15 11.2 0.4 18 4.5 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CorA PF01544.18 KXX81513.1 - 2.1e-06 27.3 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3611 PF12263.8 KXX81513.1 - 0.0036 17.2 0.5 0.005 16.8 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3611) DUF2207 PF09972.9 KXX81513.1 - 0.13 10.9 0.6 0.16 10.7 0.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MS_channel PF00924.18 KXX81514.1 - 6e-14 52.1 0.5 1.2e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel XkdW PF09636.10 KXX81514.1 - 0.4 10.8 1.6 3.9 7.6 1.0 2.2 2 0 0 2 2 2 0 XkdW protein Allexi_40kDa PF05549.11 KXX81515.1 - 0.036 13.6 0.2 0.037 13.5 0.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein NAD_binding_10 PF13460.6 KXX81516.1 - 2e-08 34.4 0.0 2.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX81516.1 - 4.4e-07 29.7 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXX81516.1 - 1.6e-06 28.4 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXX81516.1 - 9.6e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 KXX81516.1 - 0.00046 21.0 0.0 0.00078 20.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 KXX81516.1 - 0.037 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 KR domain Big_3_5 PF16640.5 KXX81516.1 - 0.13 12.4 0.4 7.6 6.8 0.0 2.6 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) Esterase PF00756.20 KXX81517.1 - 5.2e-16 59.0 0.2 1.4e-14 54.4 0.2 2.2 1 1 0 1 1 1 1 Putative esterase Band_7 PF01145.25 KXX81519.1 - 2e-30 106.1 0.6 4e-30 105.1 0.6 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KXX81519.1 - 1.3e-23 82.8 0.3 1.3e-23 82.8 0.3 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 KXX81519.1 - 0.027 13.8 0.3 0.042 13.1 0.3 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein DCB PF16213.5 KXX81520.1 - 4.9e-46 156.6 7.0 7.8e-45 152.7 4.8 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KXX81520.1 - 2.4e-40 138.0 6.4 4.4e-40 137.2 0.0 3.9 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KXX81520.1 - 2e-27 95.7 8.8 5.7e-21 74.4 0.9 3.9 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 KXX81520.1 - 1e-05 25.3 2.7 0.0011 18.8 0.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Peptidase_M20 PF01546.28 KXX81521.1 - 2.2e-22 79.8 0.0 7.9e-22 78.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KXX81521.1 - 5.5e-12 46.0 8.4 0.012 16.4 0.4 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 KXX81521.1 - 5.7e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXX81521.1 - 0.0011 18.7 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PQQ_3 PF13570.6 KXX81521.1 - 0.081 13.4 0.4 3.6 8.2 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain Ge1_WD40 PF16529.5 KXX81521.1 - 0.2 10.6 0.1 0.52 9.2 0.1 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tim17 PF02466.19 KXX81522.1 - 2.6e-26 92.2 5.9 4.2e-26 91.5 5.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ank_2 PF12796.7 KXX81523.1 - 1.1e-24 86.8 0.0 1.8e-11 44.5 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX81523.1 - 1.3e-22 79.9 0.1 3.5e-08 33.8 0.0 5.2 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXX81523.1 - 1.1e-19 69.9 0.1 0.00011 22.5 0.2 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KXX81523.1 - 2.6e-17 61.1 0.1 1.4e-05 25.1 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KXX81523.1 - 7.3e-16 58.0 0.1 9.4e-07 29.0 0.1 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Cas_VVA1548 PF09652.10 KXX81523.1 - 0.038 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) SesA PF17107.5 KXX81523.1 - 0.16 12.2 2.7 0.6 10.3 0.3 2.7 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Chitin_bind_1 PF00187.19 KXX81524.1 - 0.013 16.0 19.9 0.025 15.0 19.9 1.5 1 0 0 1 1 1 0 Chitin recognition protein Cupin_2 PF07883.11 KXX81525.1 - 3e-08 33.3 0.0 5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXX81525.1 - 0.0044 16.7 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) BBS2_Mid PF14783.6 KXX81525.1 - 0.027 14.5 0.1 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Lactamase_B_2 PF12706.7 KXX81526.1 - 6.9e-23 81.2 0.2 2.6e-22 79.3 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXX81526.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXX81526.1 - 0.0025 17.8 0.2 0.078 13.0 0.4 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Asparaginase_2 PF01112.18 KXX81527.1 - 6.5e-58 196.2 0.0 2e-26 92.8 0.0 3.2 3 0 0 3 3 3 3 Asparaginase Pkinase PF00069.25 KXX81529.1 - 1.5e-47 162.2 0.0 1.9e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81529.1 - 4.1e-23 82.0 0.0 6.2e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YTH PF04146.15 KXX81529.1 - 2.9e-22 79.4 0.2 2.5e-21 76.3 0.2 2.5 1 1 0 1 1 1 1 YT521-B-like domain Kdo PF06293.14 KXX81529.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXX81529.1 - 0.015 14.7 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3176 PF11374.8 KXX81530.1 - 5.5e-17 61.9 2.3 6.4e-17 61.7 1.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3176) DoxX PF07681.12 KXX81530.1 - 0.31 11.7 2.1 0.68 10.6 0.4 2.3 2 1 0 2 2 2 0 DoxX CLLAC PF15675.5 KXX81530.1 - 1.6 8.3 4.3 5.3 6.7 4.3 1.8 1 0 0 1 1 1 0 CLLAC-motif containing domain Amino_oxidase PF01593.24 KXX81533.1 - 5e-38 131.5 0.0 1e-37 130.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX81533.1 - 1.2e-12 47.9 0.0 2.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX81533.1 - 1.3e-05 24.7 0.2 3.8e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX81533.1 - 3.6e-05 24.2 0.3 0.00047 20.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX81533.1 - 5e-05 23.0 4.0 0.00013 21.7 2.4 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX81533.1 - 0.00053 19.3 0.0 0.00084 18.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXX81533.1 - 0.00093 18.0 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KXX81533.1 - 0.0012 18.2 0.2 0.0027 17.0 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KXX81533.1 - 0.0031 16.7 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXX81533.1 - 0.0039 17.2 0.0 0.063 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXX81533.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXX81533.1 - 0.027 13.8 0.1 0.097 12.0 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXX81533.1 - 0.033 14.1 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EnY2 PF10163.9 KXX81533.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 Ank_4 PF13637.6 KXX81534.1 - 8.8e-10 38.9 0.0 4.6e-06 27.1 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX81534.1 - 1.2e-07 32.2 0.0 4.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX81534.1 - 2.8e-07 30.7 0.0 0.036 14.4 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX81534.1 - 9e-05 22.6 0.1 0.76 10.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXX81534.1 - 0.00019 21.7 0.1 0.3 11.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Helo_like_N PF17111.5 KXX81534.1 - 0.0002 20.8 0.1 0.00035 20.0 0.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF1327 PF07041.11 KXX81534.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) FUSC PF04632.12 KXX81534.1 - 0.51 8.8 3.1 3.8 5.9 0.6 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Methyltransf_23 PF13489.6 KXX81535.1 - 1.6e-22 80.1 0.0 2.5e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81535.1 - 4.3e-13 49.8 0.0 1.2e-12 48.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX81535.1 - 5.1e-10 39.9 0.0 1.4e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX81535.1 - 2e-09 38.1 0.0 1e-08 35.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX81535.1 - 6.4e-06 26.0 0.0 0.00015 21.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX81535.1 - 5.9e-05 22.5 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX81535.1 - 0.0042 16.6 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KXX81535.1 - 0.0053 16.5 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXX81535.1 - 0.0069 15.8 0.0 0.014 14.8 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KXX81535.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KXX81535.1 - 0.072 12.6 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.19 KXX81535.1 - 0.083 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pkinase PF00069.25 KXX81536.1 - 1.9e-06 27.4 0.0 6e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81536.1 - 2.5e-05 23.7 0.0 7.5e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Hrs_helical PF12210.8 KXX81536.1 - 0.074 13.6 0.5 0.19 12.3 0.4 1.8 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pox_ser-thr_kin PF05445.11 KXX81536.1 - 0.075 12.0 0.1 0.27 10.1 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ciart PF15673.5 KXX81537.1 - 0.087 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor p450 PF00067.22 KXX81538.1 - 4.3e-70 236.7 0.0 5.4e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 KXX81539.1 - 3.1e-31 108.9 0.0 3.8e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.25 KXX81541.1 - 5e-06 26.1 0.2 6.5e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81541.1 - 0.011 15.0 0.1 0.07 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase MR_MLE_C PF13378.6 KXX81542.1 - 3e-57 193.7 0.0 5.5e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXX81542.1 - 0.0011 19.1 0.1 0.0024 18.1 0.1 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KXX81542.1 - 0.0089 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Rad10 PF03834.14 KXX81544.1 - 3.7e-46 155.8 0.1 4.8e-46 155.5 0.1 1.1 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KXX81544.1 - 0.043 14.4 0.0 0.093 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Acetyltransf_1 PF00583.25 KXX81546.1 - 1e-09 38.6 0.0 2.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX81546.1 - 2.2e-09 37.3 0.0 4.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KXX81546.1 - 2.8e-08 33.7 7.8 6.1e-08 32.7 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_7 PF13508.7 KXX81546.1 - 1.1e-06 29.0 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.8 KXX81546.1 - 0.00087 18.2 0.1 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_9 PF13527.7 KXX81546.1 - 0.00093 19.3 0.0 0.0029 17.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX81546.1 - 0.0044 17.0 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXX81546.1 - 0.025 14.7 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Prot_inhib_II PF02428.15 KXX81546.1 - 5.2 7.6 7.4 3.9 8.0 5.2 1.8 1 1 1 2 2 2 0 Potato type II proteinase inhibitor family Fungal_trans PF04082.18 KXX81547.1 - 1.8e-21 76.4 0.0 3.8e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX81547.1 - 0.83 9.8 5.2 1.7 8.8 4.3 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.20 KXX81549.1 - 8.4e-139 463.4 0.0 9.7e-139 463.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DEAD PF00270.29 KXX81550.1 - 3.1e-40 137.8 0.3 4.8e-40 137.2 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX81550.1 - 2.5e-29 101.8 0.1 5.5e-28 97.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX81550.1 - 6.2e-07 29.6 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FAM110_C PF14160.6 KXX81550.1 - 0.047 14.8 0.4 0.82 10.8 0.0 2.6 2 0 0 2 2 2 0 Centrosome-associated C terminus OCRL_clath_bd PF16726.5 KXX81550.1 - 0.11 12.7 0.5 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Inositol polyphosphate 5-phosphatase clathrin binding domain DUF4834 PF16118.5 KXX81551.1 - 1.1 10.2 8.2 0.55 11.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Inv-AAD PF18785.1 KXX81552.1 - 5.9e-64 213.7 0.3 6.9e-64 213.5 0.3 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KXX81552.1 - 2.2e-14 53.2 0.0 2.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXX81552.1 - 0.00091 19.0 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KXX81552.1 - 0.00092 19.1 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Tis11B_N PF04553.12 KXX81553.1 - 0.068 13.7 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Tis11B like protein, N terminus HTH_Tnp_4 PF13613.6 KXX81553.1 - 0.089 12.5 0.3 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease DUF234 PF03008.14 KXX81553.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function RXT2_N PF08595.11 KXX81554.1 - 1.9e-47 161.2 0.1 1.9e-47 161.2 0.1 2.3 3 0 0 3 3 3 1 RXT2-like, N-terminal Glyco_hydro81C PF17652.1 KXX81555.1 - 1.3e-152 508.1 0.2 1.7e-152 507.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KXX81555.1 - 8.6e-119 396.5 0.1 1.4e-118 395.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain FGGY_C PF02782.16 KXX81556.1 - 1.4e-75 253.4 0.6 3.1e-75 252.3 0.6 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXX81556.1 - 6.4e-65 219.1 0.0 8.6e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DnaJ PF00226.31 KXX81557.1 - 3.4e-22 78.3 1.5 3.4e-22 78.3 1.5 2.1 2 0 0 2 2 2 1 DnaJ domain Nif11 PF07862.11 KXX81557.1 - 0.0057 16.9 7.1 0.38 11.1 0.0 4.1 3 1 0 3 3 3 1 Nif11 domain Stn1 PF10451.9 KXX81558.1 - 5.3e-15 55.1 0.4 4.1e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KXX81558.1 - 0.00016 21.6 0.4 0.00045 20.1 0.4 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KXX81558.1 - 0.0072 16.1 0.8 0.041 13.7 0.8 2.0 1 1 0 1 1 1 1 RecQ-mediated genome instability protein 2 NTP_transferase PF00483.23 KXX81559.1 - 1.8e-54 184.9 0.0 4.7e-54 183.6 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KXX81559.1 - 1.5e-16 59.4 15.5 1.8e-10 40.1 1.1 3.6 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXX81559.1 - 1.6e-09 38.3 0.0 2.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KXX81559.1 - 2.3e-06 27.3 0.9 2.3e-06 27.3 0.9 3.3 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXX81559.1 - 0.00041 18.6 0.1 0.0011 17.2 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) dsrm PF00035.26 KXX81560.1 - 0.00019 22.1 0.0 0.00036 21.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KXX81560.1 - 0.0083 16.4 0.1 0.015 15.6 0.1 1.6 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PXA PF02194.15 KXX81561.1 - 2e-54 184.4 1.1 4.4e-54 183.2 0.4 2.0 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KXX81561.1 - 3.2e-26 92.1 0.0 1e-25 90.5 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KXX81561.1 - 4.9e-20 71.6 0.3 1.4e-19 70.2 0.3 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KXX81561.1 - 4.9e-11 42.9 0.0 1.4e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Rbsn PF11464.8 KXX81561.1 - 0.13 12.0 1.0 0.48 10.2 1.0 2.1 1 0 0 1 1 1 0 Rabenosyn Rab binding domain RRM_1 PF00076.22 KXX81562.1 - 4.1e-23 81.0 0.1 7e-11 41.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXX81562.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 RNA binding motif MinC_N PF05209.13 KXX81562.1 - 0.2 11.7 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain HA2 PF04408.23 KXX81565.1 - 1.5e-18 67.1 0.1 2.4e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) GST_N PF02798.20 KXX81566.1 - 2.2e-11 44.0 0.0 4.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX81566.1 - 4.8e-09 36.4 0.0 7.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXX81566.1 - 6.5e-09 35.9 0.0 1.8e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX81566.1 - 8e-08 32.6 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX81566.1 - 0.00025 21.0 0.0 0.00062 19.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX81566.1 - 0.00099 19.3 0.0 0.0026 17.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF4078 PF13300.6 KXX81567.1 - 3.1e-28 97.9 19.6 3.1e-28 97.9 19.6 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Phage_GPD PF05954.11 KXX81567.1 - 0.02 14.2 0.5 0.02 14.2 0.5 2.4 1 1 2 3 3 3 0 Phage late control gene D protein (GPD) PHR PF08005.12 KXX81567.1 - 0.023 15.4 0.0 0.049 14.3 0.0 1.5 1 0 0 1 1 1 0 PHR domain APG6_N PF17675.1 KXX81567.1 - 2.5 8.6 15.7 0.31 11.6 11.2 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF5427 PF10310.9 KXX81567.1 - 3.9 6.3 17.3 0.43 9.5 6.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Homoserine_dh PF00742.19 KXX81568.1 - 6.4e-52 176.0 0.0 8.6e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KXX81568.1 - 1.7e-18 67.4 0.0 3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXX81568.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PglD_N PF17836.1 KXX81568.1 - 0.26 12.0 1.0 0.57 10.9 0.0 2.2 2 0 0 2 2 2 0 PglD N-terminal domain Methyltransf_4 PF02390.17 KXX81569.1 - 9.2e-55 184.8 0.0 1.3e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KXX81569.1 - 0.00029 21.5 0.0 0.00087 19.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX81569.1 - 0.0056 16.5 0.0 0.0078 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX81569.1 - 0.014 16.1 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXX81569.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KXX81569.1 - 0.097 12.7 0.0 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXX81569.1 - 0.17 12.5 0.0 0.7 10.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Drf_GBD PF06371.13 KXX81570.1 - 5.7e-13 48.9 2.8 1.5e-11 44.2 2.8 2.2 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain adh_short PF00106.25 KXX81571.1 - 0.00082 18.9 0.0 0.5 9.8 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase MFS_1 PF07690.16 KXX81572.1 - 5.1e-21 75.0 41.0 5.1e-21 75.0 41.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXX81572.1 - 0.0011 17.9 7.7 0.049 12.5 0.2 2.4 1 1 1 2 2 2 2 MFS_1 like family DUF805 PF05656.14 KXX81572.1 - 3.7 8.0 6.6 0.58 10.6 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF805) MFS_1 PF07690.16 KXX81573.1 - 1.1e-35 123.2 63.0 1.2e-35 123.1 60.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4044 PF13253.6 KXX81573.1 - 0.99 9.0 7.1 3.9 7.1 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) SIR2 PF02146.17 KXX81574.1 - 9.2e-35 120.2 0.0 7.7e-34 117.1 0.0 2.0 1 1 0 1 1 1 1 Sir2 family Glyco_hydro_16 PF00722.21 KXX81575.1 - 7.8e-44 149.2 0.1 7.8e-44 149.2 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Sporozoite_P67 PF05642.11 KXX81575.1 - 2.1 6.4 8.7 2.7 6.0 8.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PhoLip_ATPase_C PF16212.5 KXX81576.1 - 1e-79 267.8 17.1 1e-79 267.8 17.1 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXX81576.1 - 2.8e-27 94.2 4.2 7.2e-27 92.9 4.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXX81576.1 - 5.6e-12 45.6 0.0 3.2e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX81576.1 - 7.6e-12 46.0 2.7 5.2e-07 30.2 0.5 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXX81576.1 - 2.1e-07 30.6 0.0 5.7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXX81576.1 - 0.0009 19.1 0.5 0.0069 16.2 0.6 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Imm49 PF15575.6 KXX81576.1 - 0.17 11.6 0.8 0.77 9.5 0.0 2.3 1 1 1 2 2 2 0 Immunity protein 49 Zn_clus PF00172.18 KXX81577.1 - 0.0039 17.3 7.7 0.0081 16.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.21 KXX81578.1 - 4.5e-35 119.1 27.3 1e-08 34.8 0.4 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Acyltransferase PF01553.21 KXX81579.1 - 6.6e-09 35.5 0.0 0.00018 21.1 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase SAT PF16073.5 KXX81579.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.5 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis BRAP2 PF07576.12 KXX81580.1 - 6.1e-24 84.1 0.0 1.2e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KXX81580.1 - 1.5e-16 60.5 9.0 4.4e-16 59.0 9.0 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KXX81580.1 - 1.1e-07 32.1 8.8 1.1e-07 32.1 8.8 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX81580.1 - 1.6e-06 27.9 9.4 3.5e-06 26.7 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXX81580.1 - 1.7e-05 24.4 5.0 4.5e-05 23.1 5.0 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXX81580.1 - 0.00022 21.0 8.0 0.00056 19.7 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX81580.1 - 0.00068 19.6 4.5 0.0048 16.9 4.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXX81580.1 - 0.0007 19.8 6.6 0.0021 18.3 6.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXX81580.1 - 0.00073 19.4 7.1 0.00073 19.4 7.1 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXX81580.1 - 0.0033 17.3 6.4 0.0033 17.3 6.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXX81580.1 - 0.0065 16.3 6.7 0.0065 16.3 6.7 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KXX81580.1 - 0.015 15.2 3.0 0.015 15.2 3.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein HeLo PF14479.6 KXX81580.1 - 0.19 11.6 3.0 0.31 10.9 3.0 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation zf-ANAPC11 PF12861.7 KXX81580.1 - 0.2 11.7 5.8 0.55 10.3 5.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3450 PF11932.8 KXX81580.1 - 0.67 9.2 12.5 0.043 13.1 1.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KXX81580.1 - 0.91 10.0 16.9 0.88 10.1 2.9 2.6 1 1 1 2 2 2 0 Cell division protein ZapB DUF2205 PF10224.9 KXX81580.1 - 1.1 9.3 5.5 0.25 11.4 1.9 1.7 2 0 0 2 2 1 0 Short coiled-coil protein CtIP_N PF10482.9 KXX81580.1 - 2.9 7.9 8.3 11 6.1 8.0 2.0 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain CP12 PF02672.15 KXX81580.1 - 6.2 7.7 7.3 43 4.9 0.1 2.5 2 0 0 2 2 2 0 CP12 domain Suc_Fer-like PF06999.12 KXX81581.1 - 5.7e-70 235.2 0.0 6.9e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like UCR_hinge PF02320.16 KXX81582.1 - 7.1e-27 93.4 10.5 7.1e-27 93.4 10.5 1.9 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.14 KXX81582.1 - 0.17 10.1 9.9 0.18 10.1 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.18 KXX81582.1 - 0.18 11.7 13.9 0.2 11.5 13.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Tim54 PF11711.8 KXX81582.1 - 0.23 10.2 12.5 0.25 10.1 12.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4471 PF14740.6 KXX81582.1 - 0.27 10.4 4.1 0.37 10.0 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) RR_TM4-6 PF06459.12 KXX81582.1 - 0.28 11.0 15.4 0.35 10.6 15.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 KXX81582.1 - 0.73 10.0 14.2 0.86 9.7 14.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Pox_Ag35 PF03286.14 KXX81582.1 - 0.9 9.3 16.9 1.2 8.9 16.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF-3c_N PF05470.12 KXX81582.1 - 1.1 7.5 12.8 1.4 7.1 12.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 KXX81582.1 - 1.2 8.5 19.3 1.3 8.3 19.3 1.0 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 KXX81582.1 - 1.4 7.9 8.0 1.5 7.7 8.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 KXX81582.1 - 1.5 8.9 4.2 1.7 8.8 4.2 1.2 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.12 KXX81582.1 - 1.7 6.8 20.6 1.7 6.8 20.6 1.0 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 KXX81582.1 - 1.7 8.1 12.7 2 7.9 12.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4045 PF13254.6 KXX81582.1 - 2.2 7.8 13.3 2.5 7.6 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Mitofilin PF09731.9 KXX81582.1 - 2.3 7.0 20.1 2.8 6.7 20.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NPR3 PF03666.13 KXX81582.1 - 2.7 6.7 8.0 2.7 6.7 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 KXX81582.1 - 3 7.2 22.1 3.4 7.0 22.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Raftlin PF15250.6 KXX81582.1 - 4 6.1 11.5 4.7 5.8 11.5 1.1 1 0 0 1 1 1 0 Raftlin SAPS PF04499.15 KXX81582.1 - 4.4 6.0 10.1 4.7 5.9 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GET2 PF08690.10 KXX81582.1 - 5.9 6.5 7.4 7.4 6.1 7.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SLC12 PF03522.15 KXX81582.1 - 6.2 5.7 7.4 6.9 5.6 7.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 KXX81582.1 - 6.7 6.7 7.1 7.6 6.5 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SDA1 PF05285.12 KXX81582.1 - 7.4 5.9 22.2 8.5 5.7 22.2 1.1 1 0 0 1 1 1 0 SDA1 Sec62 PF03839.16 KXX81582.1 - 9 5.7 7.7 11 5.4 7.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DHDPS PF00701.22 KXX81584.1 - 1.4e-37 129.0 0.0 1.8e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Methyltransf_33 PF10017.9 KXX81585.1 - 2e-84 283.4 0.0 3.3e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KXX81585.1 - 2.6e-19 69.8 2.9 8.5e-12 45.2 0.4 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KXX81585.1 - 1.4e-06 28.9 0.7 3.9e-06 27.4 0.7 1.8 1 0 0 1 1 1 1 DinB superfamily IF-2B PF01008.17 KXX81586.1 - 1.4e-34 119.7 0.0 1.9e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family adh_short_C2 PF13561.6 KXX81587.1 - 1.3e-43 149.2 3.2 1.7e-41 142.3 3.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX81587.1 - 2.8e-38 131.3 2.1 3.6e-38 131.0 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX81587.1 - 4.2e-09 36.6 1.3 1.1e-08 35.2 1.3 1.7 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KXX81587.1 - 0.0017 18.5 0.3 0.0032 17.5 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KXX81587.1 - 0.0023 17.8 0.9 0.0041 17.0 0.9 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXX81587.1 - 0.091 12.1 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.16 KXX81588.1 - 8.3e-28 97.3 29.2 8.3e-28 97.3 29.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX81588.1 - 4.7e-07 29.0 6.9 4.7e-07 29.0 6.9 3.7 4 0 0 4 4 4 3 Sugar (and other) transporter CFEM PF05730.11 KXX81589.1 - 2.6e-12 46.6 11.6 2.6e-12 46.6 11.6 1.6 2 0 0 2 2 2 1 CFEM domain Med13_C PF06333.12 KXX81589.1 - 6.3 6.0 8.3 7.5 5.7 8.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain MGC-24 PF05283.11 KXX81589.1 - 6.4 7.2 13.3 11 6.4 13.3 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin p450 PF00067.22 KXX81590.1 - 1.7e-43 149.0 0.0 2.7e-36 125.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_2 PF00891.18 KXX81592.1 - 5.9e-17 61.7 0.0 8.5e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXX81592.1 - 0.00036 20.4 0.0 0.00077 19.4 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KXX81592.1 - 0.0018 18.3 0.1 0.0065 16.5 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_23 PF13489.6 KXX81592.1 - 0.011 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HTH_5 PF01022.20 KXX81592.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KXX81592.1 - 0.089 12.9 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain MKT1_N PF12247.8 KXX81592.1 - 0.13 12.6 0.0 20 5.6 0.0 2.5 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication ADH_N PF08240.12 KXX81593.1 - 3.7e-27 94.3 1.8 6.2e-27 93.6 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KXX81593.1 - 1.1e-09 38.1 0.6 2.8e-09 36.7 0.6 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 KXX81593.1 - 9.3e-08 32.1 0.4 0.00015 21.7 0.0 3.2 3 0 0 3 3 3 2 Zinc-binding dehydrogenase adh_short PF00106.25 KXX81595.1 - 3.7e-35 121.2 0.0 5.7e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81595.1 - 2.6e-25 89.4 0.0 3.6e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX81595.1 - 1.7e-07 31.4 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX81595.1 - 3.9e-05 23.2 0.0 5.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX81595.1 - 4.8e-05 23.3 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXX81595.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 KXX81595.1 - 0.069 12.9 0.4 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rft-1 PF04506.13 KXX81596.1 - 2e-149 498.6 5.6 2.4e-149 498.4 5.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KXX81596.1 - 1.7e-08 34.2 11.9 1.7e-08 34.2 11.9 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 KXX81596.1 - 0.002 17.4 0.3 0.002 17.4 0.3 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein DEAD PF00270.29 KXX81597.1 - 1.1e-48 165.3 0.0 1.6e-47 161.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX81597.1 - 2.5e-35 121.2 0.0 2.5e-32 111.5 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KXX81597.1 - 2.9e-05 24.2 0.1 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KXX81597.1 - 0.0071 15.2 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Zip PF02535.22 KXX81597.1 - 0.25 10.5 1.5 0.38 9.9 1.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CMS1 PF14617.6 KXX81597.1 - 0.32 10.3 0.0 0.32 10.3 0.0 3.3 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit MARVEL PF01284.23 KXX81598.1 - 0.0025 17.8 22.7 0.0037 17.3 22.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 KXX81598.1 - 1.7 6.8 13.7 2.2 6.4 13.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4181 PF13789.6 KXX81598.1 - 4.2 7.7 11.2 1.6 9.0 8.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) Glycos_transf_2 PF00535.26 KXX81601.1 - 3.7e-36 124.5 0.0 4.5e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXX81601.1 - 4.6e-14 52.9 0.0 6e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXX81601.1 - 1.4e-05 24.6 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KXX81601.1 - 1.5e-05 24.6 0.0 2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KXX81601.1 - 0.0067 16.9 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 E1-E2_ATPase PF00122.20 KXX81602.1 - 1.8e-38 131.9 4.5 2.1e-38 131.6 2.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXX81602.1 - 3.9e-29 101.7 1.3 3.9e-29 101.7 1.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KXX81602.1 - 1e-20 73.6 0.0 2.5e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXX81602.1 - 4.4e-19 69.6 1.3 1.3e-14 55.0 0.2 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXX81602.1 - 8.6e-13 47.8 0.0 2.1e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXX81602.1 - 4.5e-07 29.9 0.5 1e-05 25.4 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1206 PF06724.11 KXX81602.1 - 0.1 12.7 1.4 25 5.0 0.0 3.9 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1206) MSA-2c PF12238.8 KXX81603.1 - 0.00098 19.2 3.9 0.00098 19.2 3.9 2.1 2 0 0 2 2 2 1 Merozoite surface antigen 2c DUF1465 PF07323.12 KXX81603.1 - 0.085 12.7 0.4 0.2 11.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Pkinase PF00069.25 KXX81604.1 - 4e-51 173.9 0.0 5.3e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81604.1 - 3.2e-22 79.0 0.0 6.4e-22 78.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXX81604.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KXX81604.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FAD_binding_3 PF01494.19 KXX81605.1 - 1.5e-78 264.5 0.0 2.1e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX81605.1 - 0.0057 15.9 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX81605.1 - 0.015 14.9 1.6 0.048 13.2 0.5 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX81605.1 - 0.017 15.3 1.5 0.038 14.2 1.5 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX81605.1 - 0.027 13.6 1.0 0.047 12.8 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXX81605.1 - 0.043 14.4 0.1 0.49 11.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXX81605.1 - 0.058 12.4 0.3 0.12 11.3 0.3 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXX81605.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family RSN1_7TM PF02714.15 KXX81606.1 - 2.3e-78 263.3 22.7 4e-78 262.5 22.7 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXX81606.1 - 2.8e-39 134.4 2.4 2.8e-39 134.4 2.4 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXX81606.1 - 3.9e-39 134.7 0.0 5.6e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PfkB PF00294.24 KXX81607.1 - 2.3e-52 178.2 2.8 3e-43 148.3 1.3 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase eIF3_subunit PF08597.10 KXX81608.1 - 1.1e-74 251.4 28.5 1.4e-74 251.1 28.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit VSG_B PF13206.6 KXX81608.1 - 0.28 10.4 17.8 0.53 9.5 11.7 2.0 2 0 0 2 2 2 0 Trypanosomal VSG domain Vpu PF00558.19 KXX81608.1 - 2.9 7.7 8.1 8.3 6.3 8.1 1.8 1 0 0 1 1 1 0 Vpu protein DAG_kinase_N PF14513.6 KXX81608.1 - 4.6 7.4 8.1 15 5.7 4.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Presenilin PF01080.17 KXX81608.1 - 5.6 5.6 12.8 0.73 8.5 8.6 1.6 2 0 0 2 2 2 0 Presenilin DUF4407 PF14362.6 KXX81608.1 - 8.6 5.6 19.4 1.9 7.7 14.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nop53 PF07767.11 KXX81608.1 - 8.7 5.6 33.9 8.6 5.6 25.6 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.12 KXX81609.1 - 0.002 17.5 1.8 0.0033 16.8 1.8 1.2 1 0 0 1 1 1 1 NOA36 protein GvpG PF05120.12 KXX81609.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein G zf-C2H2_4 PF13894.6 KXX81609.1 - 0.59 11.1 10.1 4.8 8.3 0.8 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger MDM31_MDM32 PF08118.11 KXX81610.1 - 6.2e-256 850.1 0.0 7.3e-256 849.9 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.29 KXX81611.1 - 0.032 14.1 0.7 0.076 12.8 0.7 1.6 1 0 0 1 1 1 0 KH domain adh_short_C2 PF13561.6 KXX81612.1 - 1.8e-35 122.6 5.9 3e-35 121.9 5.9 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX81612.1 - 1.4e-30 106.2 1.4 1.9e-30 105.8 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX81612.1 - 2.6e-09 37.3 4.1 3.5e-08 33.6 4.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX81612.1 - 5.4e-05 22.8 0.7 0.00081 18.9 0.7 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX81612.1 - 0.0014 18.1 0.0 0.0084 15.5 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXX81612.1 - 0.0038 16.4 0.1 0.0052 16.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KXX81612.1 - 0.03 14.9 0.6 0.057 14.0 0.6 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PDZ PF00595.24 KXX81612.1 - 0.042 14.2 0.1 0.082 13.3 0.1 1.4 1 0 0 1 1 1 0 PDZ domain Shikimate_DH PF01488.20 KXX81612.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Phage_Coat_Gp8 PF05371.12 KXX81612.1 - 0.17 11.7 1.5 5 7.0 0.1 3.2 3 0 0 3 3 3 0 Phage major coat protein, Gp8 Rad60-SLD PF11976.8 KXX81613.1 - 1.2e-15 57.1 0.3 1.6e-14 53.4 0.7 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXX81613.1 - 0.013 15.2 0.1 0.056 13.2 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin family GFA PF04828.14 KXX81614.1 - 6.9e-08 32.7 9.6 2e-05 24.8 0.3 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KXX81614.1 - 0.094 12.9 0.1 0.094 12.9 0.1 2.5 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like BCDHK_Adom3 PF10436.9 KXX81615.1 - 1.1e-47 161.8 0.1 2.5e-47 160.8 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXX81615.1 - 3.2e-11 43.7 0.0 1.5e-10 41.6 0.0 2.1 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KH_10 PF17905.1 KXX81615.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 GLD-3 KH domain 5 RIBIOP_C PF04950.12 KXX81616.1 - 3.7e-93 312.1 0.0 3.7e-93 312.1 0.0 2.1 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXX81616.1 - 1.9e-27 95.2 0.0 5.8e-27 93.6 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KXX81616.1 - 4.7e-05 23.7 0.2 0.00015 22.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXX81616.1 - 6.5e-05 23.4 0.1 0.00025 21.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KXX81616.1 - 0.00041 20.0 0.0 0.081 12.5 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXX81616.1 - 0.00045 20.7 1.1 0.004 17.7 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KXX81616.1 - 0.00055 20.4 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXX81616.1 - 0.00076 19.7 0.9 0.0018 18.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 KXX81616.1 - 0.00098 19.2 0.1 0.0044 17.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KXX81616.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.7 1 1 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 KXX81616.1 - 0.0049 16.6 0.0 0.019 14.7 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KXX81616.1 - 0.0063 17.1 11.9 0.039 14.5 0.0 3.7 4 0 0 4 4 2 2 AAA domain AAA_30 PF13604.6 KXX81616.1 - 0.0072 16.1 0.0 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX81616.1 - 0.0081 16.5 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX81616.1 - 0.01 15.8 0.0 0.29 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KXX81616.1 - 0.014 14.6 0.9 0.024 13.8 0.0 1.7 2 0 0 2 2 1 0 NB-ARC domain cobW PF02492.19 KXX81616.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KXX81616.1 - 0.019 15.0 0.0 0.064 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXX81616.1 - 0.02 15.3 0.0 0.056 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 KXX81616.1 - 0.028 14.6 0.3 0.12 12.6 0.0 2.3 3 0 0 3 3 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXX81616.1 - 0.032 14.1 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 KXX81616.1 - 0.041 13.8 0.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Ploopntkinase3 PF18751.1 KXX81616.1 - 0.049 13.6 1.0 0.069 13.1 0.0 1.7 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 KXX81616.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 KXX81616.1 - 0.07 13.0 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 KXX81616.1 - 0.083 12.5 0.0 0.32 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXX81616.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 KXX81616.1 - 0.21 12.0 8.0 0.3 11.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXX81616.1 - 0.33 10.8 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea DUF3435 PF11917.8 KXX81616.1 - 0.49 9.3 9.5 1.1 8.1 9.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) NTPase_1 PF03266.15 KXX81616.1 - 1.6 8.7 5.9 0.12 12.3 0.2 2.0 2 0 0 2 2 1 0 NTPase AAA_23 PF13476.6 KXX81616.1 - 3.7 8.0 0.0 3.7 8.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain Herpes_LMP1 PF05297.11 KXX81616.1 - 4 6.5 9.0 8.3 5.5 9.0 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Radical_SAM PF04055.21 KXX81617.1 - 1.3e-05 25.6 0.0 2.6e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXX81617.1 - 0.0035 17.6 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1681 PF07933.14 KXX81618.1 - 1.4e-52 177.4 0.0 1.8e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SH3_2 PF07653.17 KXX81618.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Ank_2 PF12796.7 KXX81619.1 - 8.2e-91 298.7 0.7 1.9e-11 44.4 0.0 17.5 7 4 14 21 21 21 18 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX81619.1 - 1.9e-86 283.4 19.0 2.5e-06 27.9 0.1 25.9 18 5 7 27 27 27 15 Ankyrin repeats (many copies) Ank PF00023.30 KXX81619.1 - 1.4e-57 189.7 46.0 0.0016 18.8 0.0 27.4 29 2 0 29 29 29 14 Ankyrin repeat Ank_5 PF13857.6 KXX81619.1 - 8.2e-53 175.8 50.1 1.7e-05 25.0 0.3 23.6 19 5 9 28 28 28 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX81619.1 - 9.9e-50 160.7 31.3 0.0011 19.3 0.0 28.7 31 2 0 31 31 31 9 Ankyrin repeat NACHT PF05729.12 KXX81619.1 - 2e-12 47.3 0.0 1.1e-09 38.5 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KXX81619.1 - 3.5e-07 30.8 0.3 2.1e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX81619.1 - 0.013 15.8 0.0 0.043 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXX81619.1 - 0.044 13.5 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 KXX81619.1 - 0.06 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Chitin_synth_2 PF03142.15 KXX81620.1 - 4.2e-251 834.1 1.3 5.6e-251 833.7 1.3 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KXX81620.1 - 3.3e-74 250.3 0.0 7.5e-74 249.2 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KXX81620.1 - 2.6e-17 62.5 0.0 1e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KXX81620.1 - 1.4e-12 47.6 0.0 1.3e-09 38.1 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KXX81620.1 - 1.8e-11 44.3 6.4 6.8e-11 42.4 6.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXX81620.1 - 2.8e-11 43.8 0.1 4e-10 40.0 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXX81620.1 - 2e-05 24.4 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 TrwB_AAD_bind PF10412.9 KXX81620.1 - 0.0038 16.2 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 KXX81620.1 - 0.0073 16.7 0.1 0.037 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Glyco_transf_21 PF13506.6 KXX81620.1 - 0.025 14.1 0.2 0.087 12.3 0.2 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 21 AAA_7 PF12775.7 KXX81620.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KXX81620.1 - 0.073 13.3 0.1 0.35 11.1 0.1 2.2 1 0 0 1 1 1 0 AAA domain DUF1622 PF07784.11 KXX81620.1 - 0.12 12.3 0.4 11 6.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) G-alpha PF00503.20 KXX81620.1 - 0.13 11.4 0.1 1.4 8.0 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Chitin_synth_2 PF03142.15 KXX81621.1 - 4.5e-229 761.4 0.0 6.6e-229 760.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KXX81621.1 - 2.2e-15 56.3 2.3 1.9e-14 53.3 3.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KXX81621.1 - 2.1e-14 53.4 0.0 3.4e-08 33.5 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KXX81621.1 - 9e-14 51.8 5.2 1.4e-13 51.3 3.9 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXX81621.1 - 1.4e-11 44.7 0.0 1.1e-10 41.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KXX81621.1 - 3.8e-07 28.7 0.0 3.3e-06 25.6 0.0 2.4 3 1 0 3 3 3 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KXX81621.1 - 0.00081 18.9 0.0 0.003 17.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXX81621.1 - 0.0013 18.6 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pkinase PF00069.25 KXX81622.1 - 0.00067 19.1 0.0 0.0025 17.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXX81622.1 - 0.096 12.6 0.4 0.94 9.3 0.8 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Aldolase_II PF00596.21 KXX81623.1 - 2.6e-23 82.9 0.4 3.6e-23 82.4 0.4 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ala_racemase_N PF01168.20 KXX81625.1 - 2.7e-24 86.0 0.0 3.3e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain F-box-like PF12937.7 KXX81626.1 - 4.5e-07 29.7 0.3 1e-06 28.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX81626.1 - 0.031 14.2 0.8 0.031 14.2 0.8 2.8 2 1 0 2 2 2 0 F-box domain DUF4954 PF16314.5 KXX81626.1 - 0.13 10.4 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) tRNA-synt_1 PF00133.22 KXX81628.1 - 3.3e-224 745.6 0.0 5e-224 745.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXX81628.1 - 7.3e-27 94.2 0.0 3.2e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXX81628.1 - 2.8e-16 59.3 0.2 1.4e-06 27.3 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KXX81628.1 - 0.011 15.1 0.0 0.089 12.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L26 PF16906.5 KXX81630.1 - 1.5e-39 134.4 2.5 1.9e-39 134.0 2.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KXX81630.1 - 4.1e-06 26.5 1.4 1.1e-05 25.2 1.4 1.7 1 0 0 1 1 1 1 KOW motif Sfi1 PF08457.10 KXX81631.1 - 1.1e-145 486.5 86.6 3.2e-142 475.0 79.5 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Cupin_8 PF13621.6 KXX81631.1 - 0.18 11.5 3.8 0.085 12.6 0.9 2.0 2 1 0 2 2 2 0 Cupin-like domain Mo25 PF08569.11 KXX81633.1 - 2.4e-128 428.1 0.0 2.7e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Hpt PF01627.23 KXX81633.1 - 0.039 14.2 0.2 0.084 13.2 0.2 1.5 1 0 0 1 1 1 0 Hpt domain Mito_carr PF00153.27 KXX81634.1 - 9.6e-30 102.4 0.3 3.4e-14 52.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.7 KXX81635.1 - 0.0052 17.2 2.8 20 5.8 0.0 5.2 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXX81635.1 - 0.069 13.2 1.2 27 5.2 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Pkinase PF00069.25 KXX81636.1 - 4.1e-69 232.9 0.0 5.5e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81636.1 - 3.3e-35 121.6 0.0 5.5e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX81636.1 - 2.5e-05 23.7 1.3 0.01 15.2 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KXX81636.1 - 0.00076 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX81636.1 - 0.0041 17.1 0.1 0.017 15.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXX81636.1 - 0.023 13.6 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KXX81636.1 - 0.1 12.2 0.1 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RHD3 PF05879.12 KXX81637.1 - 0 1080.2 0.0 0 1079.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KXX81637.1 - 1.3e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KXX81637.1 - 4.3e-06 26.9 0.0 8.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXX81637.1 - 0.00012 22.1 0.0 0.00031 20.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXX81637.1 - 0.0011 19.2 0.1 0.0034 17.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KXX81637.1 - 0.06 12.6 0.1 0.16 11.3 0.1 1.6 2 0 0 2 2 2 0 Septin Amidohydro_1 PF01979.20 KXX81638.1 - 4.7e-61 207.0 0.0 5.9e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXX81638.1 - 3.5e-15 56.4 0.5 1.2e-11 44.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KXX81638.1 - 0.00051 19.5 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Adenosine/AMP deaminase Dpy-30 PF05186.13 KXX81638.1 - 0.077 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Dpy-30 motif Fructosamin_kin PF03881.14 KXX81639.1 - 4.6e-61 206.6 0.0 5.6e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXX81639.1 - 0.0067 16.4 0.0 0.0099 15.8 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXX81639.1 - 0.29 9.9 0.0 0.41 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) zf-C2H2 PF00096.26 KXX81640.1 - 5.4e-05 23.4 8.7 0.02 15.3 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX81640.1 - 0.0046 17.7 7.8 0.083 13.8 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Docking PF08990.11 KXX81640.1 - 0.1 12.2 2.1 0.23 11.1 2.1 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking zf-C2H2_jaz PF12171.8 KXX81640.1 - 0.26 11.6 3.3 1.2 9.5 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Hexapep PF00132.24 KXX81641.1 - 1.1e-06 28.1 3.0 0.0002 20.9 0.7 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KXX81641.1 - 2.6e-06 26.6 2.0 0.00014 20.9 2.0 2.1 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KXX81641.1 - 1.5e-05 25.4 0.0 2.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KXX81641.1 - 0.00043 19.9 0.0 0.00092 18.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KXX81641.1 - 0.012 13.7 1.2 0.024 12.8 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) TFIIA PF03153.13 KXX81641.1 - 0.017 15.1 6.6 0.023 14.7 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hexapep_2 PF14602.6 KXX81641.1 - 0.13 12.1 6.5 0.39 10.5 2.3 2.9 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Cwf_Cwc_15 PF04889.12 KXX81641.1 - 5.7 6.6 19.0 9 5.9 19.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hva1_TUDOR PF11160.8 KXX81642.1 - 4.2e-13 49.2 0.1 4.8e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Glyco_hydro_61 PF03443.14 KXX81643.1 - 3.6e-55 187.1 0.6 4.8e-55 186.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KXX81643.1 - 0.022 15.0 0.1 0.089 13.1 0.0 2.0 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_61 PF03443.14 KXX81644.1 - 1.1e-52 179.0 0.1 1.4e-52 178.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Med18 PF09637.10 KXX81645.1 - 2.6e-19 70.1 0.1 3e-19 69.9 0.1 1.0 1 0 0 1 1 1 1 Med18 protein adh_short PF00106.25 KXX81646.1 - 2.6e-19 69.5 0.0 3.1e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81646.1 - 1.3e-14 54.3 0.0 1.6e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX81646.1 - 4.7e-09 36.4 0.1 1e-08 35.3 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXX81646.1 - 8.2e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXX81646.1 - 0.05 13.9 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Calici_MSP PF05752.11 KXX81646.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Calicivirus minor structural protein RNA_pol_Rpb6 PF01192.22 KXX81646.1 - 0.095 12.6 0.3 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb6 MS_channel PF00924.18 KXX81647.1 - 3.8e-21 75.6 2.5 7.5e-21 74.6 2.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 KXX81647.1 - 0.00079 19.8 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXX81647.1 - 0.00099 18.5 0.1 0.0021 17.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KXX81647.1 - 0.0049 16.3 0.2 0.012 15.1 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXX81647.1 - 0.064 13.2 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain DLH PF01738.18 KXX81648.1 - 1.8e-27 96.3 0.0 2.6e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXX81648.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KXX81648.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Apolipoprotein PF01442.18 KXX81649.1 - 0.0017 18.3 8.2 0.0017 18.3 8.2 11.1 3 2 6 9 9 9 2 Apolipoprotein A1/A4/E domain Gp_dh_C PF02800.20 KXX81649.1 - 0.014 15.0 6.2 0.97 9.0 0.2 3.8 2 1 1 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain MEF2_binding PF09047.10 KXX81649.1 - 0.032 14.1 0.2 0.96 9.3 0.0 2.9 2 0 0 2 2 2 0 MEF2 binding Fer2_BFD PF04324.15 KXX81649.1 - 0.3 11.5 4.5 1.5e+02 2.8 0.0 6.8 8 0 0 8 8 8 0 BFD-like [2Fe-2S] binding domain SO_alpha_A3 PF17806.1 KXX81649.1 - 0.72 10.2 2.5 2.2e+02 2.2 0.1 5.2 4 1 1 5 5 5 0 Sarcosine oxidase A3 domain Cas6_N PF17952.1 KXX81649.1 - 1.9 8.8 3.9 2.1 8.7 0.3 2.8 2 1 1 3 3 3 0 Cas6 N-terminal domain Radical_SAM PF04055.21 KXX81649.1 - 4.4 7.7 5.8 3.1 8.1 0.1 3.6 4 0 0 4 4 4 0 Radical SAM superfamily Glyco_hydro_67N PF03648.14 KXX81649.1 - 4.9 7.5 6.6 2.1 8.7 0.1 3.7 2 1 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus tRNA-synt_2b PF00587.25 KXX81650.1 - 1.2e-20 74.2 0.0 1.8e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXX81650.1 - 8.4e-13 48.5 0.9 3e-12 46.7 0.9 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 KXX81650.1 - 0.37 11.0 3.9 0.89 9.7 3.9 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) RNA12 PF10443.9 KXX81651.1 - 1.6e-164 547.9 1.0 2e-164 547.6 1.0 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 KXX81651.1 - 1e-06 28.4 0.0 5e-06 26.2 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 KXX81651.1 - 0.0004 20.4 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) Fungal_trans_2 PF11951.8 KXX81652.1 - 2.3e-12 46.5 0.2 4e-12 45.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX81652.1 - 4.6e-06 26.6 15.2 9.4e-06 25.7 15.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KXX81652.1 - 0.047 13.8 8.0 0.12 12.5 8.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Hydin_ADK PF17213.3 KXX81652.1 - 0.24 11.7 1.6 0.44 10.8 1.6 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Med3 PF11593.8 KXX81652.1 - 1.2 8.3 9.7 1.7 7.7 9.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 KXX81652.1 - 2.3 7.8 10.0 3.5 7.2 10.0 1.2 1 0 0 1 1 1 0 Spt20 family HSP70 PF00012.20 KXX81653.1 - 1.1e-248 826.4 2.9 1.3e-248 826.2 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXX81653.1 - 6.3e-17 61.4 0.0 1e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXX81653.1 - 0.0022 17.7 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KXX81653.1 - 0.0023 18.3 0.6 3.1 8.3 0.0 3.3 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KXX81653.1 - 0.017 14.4 0.1 0.036 13.3 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KXX81653.1 - 0.034 13.4 0.2 0.076 12.2 0.0 1.6 2 0 0 2 2 2 0 StbA protein DUF3128 PF11326.8 KXX81654.1 - 3.5e-27 94.6 2.5 6.4e-27 93.7 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ndc1_Nup PF09531.10 KXX81654.1 - 0.3 9.7 7.1 0.32 9.6 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 KXX81654.1 - 6.5 6.2 8.1 1.2 8.6 4.6 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RNA_pol_Rpc82 PF05645.13 KXX81655.1 - 4.6e-61 206.8 0.0 9.5e-61 205.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KXX81655.1 - 3.4e-19 68.7 0.6 8.6e-16 57.8 0.0 3.8 3 1 1 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KXX81655.1 - 0.00079 19.3 0.2 0.81 9.6 0.0 4.1 4 1 0 4 4 4 2 TFIIE alpha subunit ATP-synt_Eps PF04627.13 KXX81656.1 - 4.7e-21 74.5 2.9 4.7e-21 74.5 2.9 2.2 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.20 KXX81656.1 - 3.8e-16 59.4 0.0 6.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXX81656.1 - 3.8e-13 49.8 0.0 9.1e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 KXX81656.1 - 0.13 11.3 0.1 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase M16C associated Mak10 PF04112.13 KXX81657.1 - 1e-61 207.4 0.0 1.6e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.27 KXX81658.1 - 1.2e-51 172.6 5.4 2.4e-16 59.4 0.5 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Abp2 PF09441.10 KXX81659.1 - 8.5e-87 289.6 0.0 1.3e-86 289.0 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Acetyltransf_4 PF13420.7 KXX81660.1 - 0.053 13.7 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain V_ATPase_I PF01496.19 KXX81661.1 - 0.033 12.1 1.1 0.047 11.6 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Actin PF00022.19 KXX81662.1 - 6.1e-12 44.9 0.0 1.2e-10 40.6 0.0 2.7 1 1 0 1 1 1 1 Actin GEN1_C PF18380.1 KXX81663.1 - 9.2e-33 113.3 0.1 3e-32 111.6 0.1 2.0 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KXX81663.1 - 2.2e-24 85.6 0.0 4.5e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXX81663.1 - 9.8e-08 32.4 0.0 2.2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain SWIB PF02201.18 KXX81664.1 - 1.3e-23 82.6 0.2 3e-23 81.5 0.1 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain RNase_HII PF01351.18 KXX81666.1 - 5e-46 157.0 0.0 8.4e-42 143.3 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII Adeno_VII PF03228.14 KXX81666.1 - 0.24 12.0 1.1 0.43 11.2 0.1 1.8 2 0 0 2 2 2 0 Adenoviral core protein VII HET PF06985.11 KXX81668.1 - 7.1e-22 78.3 0.1 1.3e-21 77.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mif2_N PF15624.6 KXX81669.1 - 1.1e-42 145.9 1.0 1.1e-42 145.9 1.0 4.0 3 1 0 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 KXX81669.1 - 4.7e-34 116.4 0.5 7.4e-34 115.8 0.5 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KXX81669.1 - 5.1e-05 22.9 0.0 0.00017 21.2 0.0 2.0 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXX81669.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 KXX81669.1 - 0.13 12.0 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Cupin DUF3446 PF11928.8 KXX81670.1 - 0.004 17.4 2.5 0.0049 17.1 2.5 1.3 1 0 0 1 1 1 1 Early growth response N-terminal domain Clr5 PF14420.6 KXX81671.1 - 8.4e-16 57.9 2.9 2.7e-15 56.3 2.9 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KXX81671.1 - 5.5e-07 29.8 0.0 0.025 14.9 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXX81671.1 - 2.5e-05 24.0 0.0 0.027 14.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Pex14_N PF04695.13 KXX81671.1 - 0.021 15.5 3.7 0.068 13.8 3.7 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_14 PF13428.6 KXX81671.1 - 0.026 15.3 0.1 10 7.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXX81671.1 - 0.059 13.4 0.1 13 6.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 KXX81671.1 - 0.081 12.6 0.0 22 4.7 0.0 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 RNase_T PF00929.24 KXX81674.1 - 8.3e-27 94.7 0.0 9.5e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Exonuclease GFO_IDH_MocA PF01408.22 KXX81675.1 - 1.1e-11 45.7 0.0 2.8e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXX81675.1 - 2.9e-05 24.0 0.0 6.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.16 KXX81677.1 - 4.5e-33 113.9 0.0 6.4e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXX81677.1 - 4.1e-26 91.4 0.0 9.7e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXX81677.1 - 2.6e-15 56.9 0.0 5.9e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KXX81677.1 - 4.7e-06 26.7 0.0 9.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ATG11 PF10377.9 KXX81678.1 - 8.2e-46 155.3 0.2 8.2e-46 155.3 0.2 3.0 3 1 0 3 3 3 1 Autophagy-related protein 11 Tropomyosin PF00261.20 KXX81678.1 - 0.00019 20.9 6.8 0.00019 20.9 6.8 8.1 7 2 1 8 8 8 1 Tropomyosin DHR10 PF18595.1 KXX81678.1 - 0.0035 17.4 15.3 0.0035 17.4 15.3 7.8 7 1 2 9 9 9 1 Designed helical repeat protein 10 domain FERM_f0 PF16511.5 KXX81678.1 - 0.0069 16.7 0.1 1.1 9.6 0.0 2.8 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM Protoglobin PF11563.8 KXX81678.1 - 0.028 14.3 3.2 3.8 7.4 0.2 2.7 2 0 0 2 2 2 0 Protoglobin NuA4 PF09340.10 KXX81678.1 - 0.33 10.9 7.5 7.2 6.6 0.0 4.6 4 0 0 4 4 4 0 Histone acetyltransferase subunit NuA4 MCPsignal PF00015.21 KXX81678.1 - 1.6 8.5 9.2 0.16 11.7 1.7 3.3 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HMG_box PF00505.19 KXX81679.1 - 2e-25 89.0 1.0 2.7e-25 88.5 1.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXX81679.1 - 4.3e-18 65.7 1.8 6.1e-18 65.2 1.8 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KXX81679.1 - 0.0015 19.0 2.3 0.0033 18.0 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KXX81679.1 - 0.017 15.0 0.2 0.03 14.3 0.2 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 KXX81679.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain AATase PF07247.12 KXX81680.1 - 1.8e-15 56.5 0.0 3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KXX81680.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Ribosomal_L9_N PF01281.19 KXX81681.1 - 7.7e-12 44.6 0.0 1.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 KXX81681.1 - 0.0061 17.0 0.0 0.033 14.6 0.0 2.1 2 1 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Ten_N PF06484.12 KXX81681.1 - 0.061 13.2 0.3 0.079 12.8 0.3 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region Cyclin_N PF00134.23 KXX81682.1 - 6.8e-45 151.9 0.1 1.5e-44 150.8 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXX81682.1 - 4.7e-34 117.0 0.1 7.9e-34 116.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain HJURP_mid PF12346.8 KXX81682.1 - 2.8 8.4 6.8 1.8 9.0 0.4 2.7 1 1 2 3 3 3 0 Holliday junction recognition protein-associated repeat Ribosomal_L2_C PF03947.18 KXX81683.1 - 1.4e-52 177.2 3.2 2.8e-52 176.2 2.8 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXX81683.1 - 1.3e-26 92.4 0.2 3e-26 91.2 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain AC_N PF16214.5 KXX81684.1 - 0.44 9.6 2.6 0.49 9.5 2.6 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region PHD PF00628.29 KXX81686.1 - 5.3e-09 35.8 9.2 1.2e-08 34.7 9.2 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXX81686.1 - 0.013 15.0 4.3 0.028 14.0 4.3 1.6 1 0 0 1 1 1 0 PHD-finger Ion_trans PF00520.31 KXX81687.1 - 2e-128 426.8 78.7 7.5e-43 146.5 0.9 4.7 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 KXX81687.1 - 0.064 12.8 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KXX81687.1 - 0.07 13.6 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair MMgT PF10270.9 KXX81688.1 - 5.9e-36 122.8 0.0 7e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter HMG_box PF00505.19 KXX81689.1 - 3.6e-10 40.1 2.4 9.2e-10 38.8 2.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXX81689.1 - 0.0019 18.8 1.5 0.0055 17.3 1.4 1.9 2 0 0 2 2 2 1 HMG-box domain MATalpha_HMGbox PF04769.12 KXX81689.1 - 0.033 13.5 0.1 0.057 12.7 0.1 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box CFEM PF05730.11 KXX81690.1 - 0.0044 17.1 4.2 0.0078 16.3 4.2 1.4 1 0 0 1 1 1 1 CFEM domain PP_M1 PF03012.14 KXX81690.1 - 2.2 7.8 3.5 3.3 7.2 3.5 1.2 1 0 0 1 1 1 0 Phosphoprotein MutS_V PF00488.21 KXX81691.1 - 9.2e-38 130.2 0.0 3.7e-36 124.9 0.0 2.2 1 1 0 1 1 1 1 MutS domain V AAA_14 PF13173.6 KXX81691.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXX81691.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2946 PF11162.8 KXX81692.1 - 0.036 14.7 1.6 0.11 13.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) LSM PF01423.22 KXX81694.1 - 5.7e-19 67.6 0.1 6.8e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXX81694.1 - 0.005 17.0 0.1 0.0058 16.8 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KXX81694.1 - 0.09 12.9 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain HSP20 PF00011.21 KXX81695.1 - 9.2e-18 64.3 0.0 2.3e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXX81695.1 - 0.0001 21.8 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA YTH PF04146.15 KXX81696.1 - 3.5e-63 212.5 0.0 5.6e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KXX81696.1 - 0.0015 18.3 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 KXX81697.1 - 2.2e-30 105.6 0.2 4.6e-30 104.5 0.2 1.7 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 KXX81698.1 - 4.7e-38 131.4 0.0 9.1e-36 123.9 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KXX81698.1 - 2.5e-23 82.4 0.0 5.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.21 KXX81699.1 - 1.1e-23 84.1 13.3 1.4e-23 83.7 13.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXX81699.1 - 5.3e-06 26.5 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DMRL_synthase PF00885.19 KXX81701.1 - 3.8e-57 192.1 0.0 5e-57 191.7 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Fungal_trans PF04082.18 KXX81702.1 - 5.5e-20 71.5 0.1 1.8e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX81702.1 - 2.4e-08 34.0 8.7 2.4e-08 34.0 8.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KXX81703.1 - 3.4e-18 65.7 5.0 6.8e-05 23.6 0.2 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81703.1 - 2.1e-13 50.4 0.0 0.17 12.2 0.0 5.7 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX81703.1 - 0.0072 15.0 0.0 0.033 12.9 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF1513 PF07433.11 KXX81703.1 - 0.0093 15.1 0.0 0.088 11.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KXX81703.1 - 0.022 13.3 0.0 1.8 7.0 0.0 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain Frtz PF11768.8 KXX81703.1 - 0.083 11.2 0.0 0.22 9.8 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Oxysterol_BP PF01237.18 KXX81704.1 - 1.8e-62 211.3 0.2 2.8e-60 204.1 0.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein UCH PF00443.29 KXX81705.1 - 9.2e-35 120.4 0.0 3.6e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX81705.1 - 8.5e-07 28.9 0.0 0.0039 16.8 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase TPR_12 PF13424.6 KXX81706.1 - 1.9e-08 34.5 5.1 0.0008 19.7 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX81706.1 - 1.4e-07 31.9 6.4 8.2e-05 23.0 0.1 4.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX81706.1 - 1.9e-07 30.7 0.3 0.034 14.2 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX81706.1 - 3.1e-06 26.8 0.0 0.068 13.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX81706.1 - 3.1e-06 27.7 6.2 0.00019 22.0 0.9 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXX81706.1 - 1.5e-05 24.8 0.0 0.1 12.8 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX81706.1 - 5.4e-05 23.7 9.8 1.1 10.3 0.0 6.0 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX81706.1 - 0.0016 18.2 0.0 0.35 10.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX81706.1 - 0.018 15.3 0.1 0.65 10.3 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXX81706.1 - 0.031 14.9 4.6 52 4.8 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXX81706.1 - 0.044 13.4 3.9 0.047 13.3 1.4 2.3 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) SHNi-TPR PF10516.9 KXX81706.1 - 0.054 12.9 0.1 0.69 9.4 0.0 2.5 3 0 0 3 3 3 0 SHNi-TPR DUF2681 PF10883.8 KXX81706.1 - 0.12 12.8 0.4 0.31 11.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CMS1 PF14617.6 KXX81706.1 - 0.24 10.7 0.8 3.6 6.9 0.2 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit TPR_4 PF07721.14 KXX81706.1 - 0.52 11.1 12.9 0.73 10.6 0.3 4.2 4 0 0 4 4 2 0 Tetratricopeptide repeat PPP4R2 PF09184.11 KXX81706.1 - 1.3 8.6 5.9 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 PPP4R2 TPR_9 PF13371.6 KXX81706.1 - 1.9 8.7 9.3 3.9 7.7 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat RWD PF05773.22 KXX81707.1 - 1.6e-23 83.2 0.6 2.7e-23 82.4 0.6 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KXX81707.1 - 2.4e-06 27.9 8.1 5.2e-06 26.8 8.1 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 KfrA_N PF11740.8 KXX81707.1 - 0.67 10.6 11.0 1.1 9.9 1.9 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term CPL PF08144.11 KXX81708.1 - 1.9e-38 132.0 0.0 2e-36 125.5 0.0 3.4 3 0 0 3 3 3 1 CPL (NUC119) domain CTI PF06934.11 KXX81708.1 - 0.0039 15.8 0.1 0.0064 15.1 0.1 1.2 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) COPR5 PF15340.6 KXX81708.1 - 0.035 14.8 1.5 0.11 13.2 0.2 2.4 2 0 0 2 2 2 0 Cooperator of PRMT5 family RNA_pol_Rpb4 PF03874.16 KXX81710.1 - 7.7e-27 94.1 1.0 9.6e-27 93.8 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.32 KXX81711.1 - 5.9e-13 49.1 4.0 0.21 12.5 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81711.1 - 0.0096 16.2 0.0 3.1 8.2 0.0 3.8 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HTH_38 PF13936.6 KXX81712.1 - 0.00033 20.3 0.5 0.011 15.4 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KXX81712.1 - 0.002 17.8 0.9 0.026 14.3 0.3 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KXX81712.1 - 0.013 15.7 0.1 0.21 11.8 0.0 2.8 2 1 0 2 2 2 0 Transposase HTH_32 PF13565.6 KXX81712.1 - 0.063 13.9 1.5 0.84 10.3 0.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KXX81712.1 - 0.066 13.0 0.2 0.18 11.6 0.2 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 KXX81712.1 - 0.19 11.6 0.1 4.1 7.3 0.0 2.8 3 1 0 3 3 3 0 Bacterial regulatory protein, arsR family Sugar_tr PF00083.24 KXX81713.1 - 1.1e-31 110.2 31.7 3.6e-19 69.0 8.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXX81713.1 - 7.7e-23 81.0 24.2 3.8e-17 62.2 12.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.10 KXX81713.1 - 0.012 15.6 1.7 0.012 15.6 1.7 3.1 2 2 1 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4131 PF13567.6 KXX81713.1 - 3 7.5 14.7 1.1 8.9 1.3 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Acetate_kinase PF00871.17 KXX81714.1 - 2.5e-85 286.5 0.0 3e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1908 PF08926.11 KXX81715.1 - 0.041 13.0 0.9 0.062 12.4 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) RIC1 PF07064.13 KXX81716.1 - 2.2e-94 315.6 0.1 3.6e-94 314.9 0.1 1.4 1 0 0 1 1 1 1 RIC1 PD40 PF07676.12 KXX81716.1 - 0.0084 16.0 0.4 0.23 11.4 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat GST_N_3 PF13417.6 KXX81717.1 - 2.1e-16 60.1 0.0 5.2e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXX81717.1 - 4.3e-16 59.0 0.0 8.5e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXX81717.1 - 9.4e-08 32.3 0.0 3.5e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXX81717.1 - 5.5e-06 26.9 0.0 9.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXX81717.1 - 1.9e-05 24.6 1.3 3.7e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXX81717.1 - 0.00022 21.4 0.0 0.00055 20.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX81717.1 - 0.027 14.6 0.3 0.09 13.0 0.0 2.1 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Spt20 PF12090.8 KXX81717.1 - 0.38 10.3 2.6 0.85 9.2 2.6 1.6 1 0 0 1 1 1 0 Spt20 family CK_II_beta PF01214.18 KXX81718.1 - 1e-76 256.8 0.1 1.3e-76 256.4 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DNA_pol_phi PF04931.13 KXX81718.1 - 8.5 4.3 7.7 11 4.0 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAP2 PF01569.21 KXX81719.1 - 1.5e-21 76.6 3.3 1.5e-21 76.6 3.3 2.8 2 1 0 2 2 2 1 PAP2 superfamily TRP PF06011.12 KXX81720.1 - 2.3e-36 125.4 22.4 8.6e-35 120.3 22.4 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXX81720.1 - 2.3e-26 92.8 0.0 3.4e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 ML-like domain HATPase_c_3 PF13589.6 KXX81721.1 - 1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KXX81721.1 - 0.00019 21.1 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KXX81721.1 - 0.00034 21.1 0.0 0.00063 20.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IF3_C PF00707.22 KXX81722.1 - 7.2e-08 32.3 0.2 1.2e-07 31.6 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KXX81722.1 - 0.00015 21.5 0.2 0.0025 17.5 0.2 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Arm PF00514.23 KXX81723.1 - 1e-74 244.5 29.7 3.9e-13 49.0 0.2 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXX81723.1 - 1.1e-18 67.3 15.2 1.2e-05 25.7 0.2 7.6 7 1 2 9 9 8 5 HEAT-like repeat HEAT_2 PF13646.6 KXX81723.1 - 2e-16 60.1 10.9 0.00053 20.3 0.1 7.1 4 3 1 6 6 6 5 HEAT repeats HEAT PF02985.22 KXX81723.1 - 3.7e-14 51.6 15.2 0.18 12.1 0.0 8.7 10 0 0 10 10 8 4 HEAT repeat Adaptin_N PF01602.20 KXX81723.1 - 3.5e-11 42.4 8.6 8.7e-07 27.9 0.5 3.3 2 1 1 3 3 3 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KXX81723.1 - 4.3e-10 39.4 2.8 9.8e-06 25.1 0.4 3.7 2 1 1 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.13 KXX81723.1 - 1.3e-09 37.9 5.4 8.3e-06 25.4 1.6 2.9 1 1 2 3 3 3 3 Armadillo-like KAP PF05804.12 KXX81723.1 - 1.3e-09 36.8 0.2 3.4e-09 35.4 0.1 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 KXX81723.1 - 6.4e-07 29.6 6.9 0.019 15.0 0.2 4.9 1 1 4 6 6 6 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KXX81723.1 - 0.00022 21.2 8.0 0.55 10.2 0.1 4.4 2 1 2 4 4 4 2 Domain of unknown function (DUF3361) Vpu PF00558.19 KXX81723.1 - 0.015 15.0 1.5 0.027 14.3 0.3 2.0 2 0 0 2 2 2 0 Vpu protein HEAT_PBS PF03130.16 KXX81723.1 - 0.017 15.8 7.2 92 4.2 0.1 6.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KXX81723.1 - 0.056 14.0 0.2 1.9 9.1 0.1 3.3 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 KXX81723.1 - 0.061 13.3 2.8 13 5.7 0.0 3.6 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 KXX81723.1 - 0.074 13.2 2.1 57 4.0 0.0 4.4 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 KXX81723.1 - 0.75 9.9 8.9 3 7.9 0.3 4.7 3 1 3 7 7 6 0 Spinocerebellar ataxia type 10 protein domain CBS PF00571.28 KXX81724.1 - 1.3e-27 96.0 8.2 9.6e-11 42.0 0.4 4.3 4 0 0 4 4 4 4 CBS domain Golgin_A5 PF09787.9 KXX81725.1 - 0.012 15.1 0.6 0.015 14.7 0.6 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3287 PF11690.8 KXX81725.1 - 0.24 11.1 1.1 0.58 9.9 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) PBP PF01161.20 KXX81726.1 - 7.1e-11 42.5 0.0 1.2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TPT PF03151.16 KXX81727.1 - 3.6e-24 85.6 23.3 4.5e-24 85.3 23.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXX81727.1 - 0.00025 21.2 43.6 0.00032 20.9 14.1 2.8 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KXX81727.1 - 0.00044 19.6 21.4 0.0048 16.1 21.4 2.1 1 1 0 1 1 1 1 UAA transporter family COMPASS-Shg1 PF05205.12 KXX81728.1 - 4.9e-25 88.2 0.0 1.3e-24 86.8 0.0 1.8 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Rox3 PF08633.10 KXX81729.1 - 2.5e-68 230.4 0.0 4.3e-68 229.6 0.0 1.4 1 0 0 1 1 1 1 Rox3 mediator complex subunit FAM216B PF15107.6 KXX81729.1 - 0.14 12.0 0.0 2.2 8.2 0.0 2.3 1 1 1 2 2 2 0 FAM216B protein family Ribosomal_L4 PF00573.22 KXX81730.1 - 2.5e-45 154.6 0.0 3.2e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Adeno_E3_CR2 PF02439.15 KXX81731.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mid2 PF04478.12 KXX81731.1 - 0.03 14.1 0.1 0.03 14.1 0.1 2.3 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor DUF676 PF05057.14 KXX81732.1 - 8.5e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXX81732.1 - 2.4e-06 27.5 0.2 6.6e-05 22.7 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXX81732.1 - 6.5e-05 23.6 6.1 6.5e-05 23.6 6.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX81732.1 - 0.00075 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 KXX81732.1 - 0.0065 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PHM7_cyt PF14703.6 KXX81732.1 - 0.0087 16.3 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Med11 PF10280.9 KXX81732.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Mediator complex protein Thioesterase PF00975.20 KXX81732.1 - 0.067 13.3 1.2 0.9 9.6 0.0 2.7 3 0 0 3 3 3 0 Thioesterase domain NinG PF05766.12 KXX81732.1 - 1.3 8.9 8.3 14 5.6 9.6 1.9 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Syntaxin PF00804.25 KXX81732.1 - 4.5 6.9 8.0 6.9 6.3 8.0 1.2 1 0 0 1 1 1 0 Syntaxin Ribosomal_S3Ae PF01015.18 KXX81733.1 - 2.1e-88 295.2 1.0 2.5e-88 295.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KXX81733.1 - 0.037 14.6 0.1 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 KXX81733.1 - 0.075 13.1 1.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Abhydrolase_1 PF00561.20 KXX81735.1 - 1.5e-25 90.3 0.0 5.4e-24 85.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX81735.1 - 2.8e-16 60.8 0.1 4.1e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX81735.1 - 9.3e-10 38.2 0.2 1.7e-09 37.3 0.2 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXX81735.1 - 0.00045 20.0 0.1 0.092 12.4 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KXX81735.1 - 0.00079 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KXX81735.1 - 0.00084 19.0 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 KXX81735.1 - 0.0062 16.5 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 KXX81735.1 - 0.054 12.4 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Palm_thioest PF02089.15 KXX81735.1 - 0.087 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF3530 PF12048.8 KXX81735.1 - 0.13 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Chlorophyllase PF07224.11 KXX81735.1 - 0.16 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ser_hydrolase PF06821.13 KXX81735.1 - 0.18 11.6 0.0 0.34 10.8 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase Ras PF00071.22 KXX81736.1 - 1.9e-47 160.9 0.0 2.2e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX81736.1 - 7.4e-27 94.0 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX81736.1 - 4.7e-09 35.9 0.0 5.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KXX81736.1 - 3.3e-05 24.4 0.0 4.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXX81736.1 - 0.0001 22.4 0.0 0.00014 21.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXX81736.1 - 0.0027 17.3 0.0 0.0075 15.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KXX81736.1 - 0.0048 16.6 0.1 0.0099 15.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRPRB PF09439.10 KXX81736.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXX81736.1 - 0.014 14.7 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KXX81736.1 - 0.015 15.4 0.0 0.023 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXX81736.1 - 0.029 14.3 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KXX81736.1 - 0.031 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXX81736.1 - 0.057 13.9 0.0 0.1 13.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KXX81736.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXX81736.1 - 0.08 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KXX81736.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 KXX81736.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ComX PF05952.12 KXX81736.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX SRP_TPR_like PF17004.5 KXX81737.1 - 5.5e-23 81.2 0.3 9.2e-21 74.0 0.1 2.5 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KXX81737.1 - 1.7e-15 57.2 13.9 1.7e-15 57.2 13.9 2.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.6 KXX81737.1 - 2.8e-05 24.3 16.8 0.14 12.5 1.2 6.4 5 1 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX81737.1 - 0.00023 21.3 4.3 0.11 12.7 0.9 4.3 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXX81737.1 - 0.0011 19.5 24.7 1.9 9.1 1.2 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 KXX81737.1 - 0.0012 19.3 11.8 0.92 10.3 0.1 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXX81737.1 - 0.0015 18.5 19.6 3.2 8.1 0.3 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXX81737.1 - 0.012 16.2 27.7 0.028 15.1 2.3 6.6 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX81737.1 - 0.05 13.8 3.2 14 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX81737.1 - 0.71 10.8 34.6 7 7.8 0.4 9.7 7 3 3 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXX81737.1 - 3.2 7.7 11.0 15 5.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat GGA_N-GAT PF18308.1 KXX81737.1 - 4.1 7.1 6.2 0.79 9.4 0.1 2.8 3 0 0 3 3 3 0 GGA N-GAT domain Glyco_hydro_115 PF15979.5 KXX81738.1 - 1.3e-131 439.0 0.1 1.8e-131 438.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXX81738.1 - 6.6e-51 172.6 0.0 2.3e-50 170.8 0.0 1.9 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain Peptidase_M14 PF00246.24 KXX81739.1 - 5e-78 262.8 0.0 6.2e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KXX81739.1 - 0.0063 16.9 0.0 0.032 14.6 0.1 2.1 2 0 0 2 2 2 1 Carboxypeptidase activation peptide DUF2817 PF10994.8 KXX81739.1 - 0.11 11.9 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2817) Sec7 PF01369.20 KXX81740.1 - 3.5e-31 108.3 0.2 5.7e-31 107.6 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KXX81740.1 - 1.9e-05 25.1 0.3 5.9e-05 23.5 0.3 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 KXX81740.1 - 9.3e-05 22.8 0.0 0.00023 21.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain GTP_CH_N PF12471.8 KXX81741.1 - 4.1e-86 287.7 0.0 7.5e-85 283.6 0.0 2.1 1 1 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KXX81741.1 - 2.4e-17 63.0 0.0 3.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.13 KXX81742.1 - 5.8e-25 87.1 0.8 5.8e-25 87.1 0.8 2.0 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KXX81742.1 - 0.24 11.5 1.7 0.54 10.4 1.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF3084 PF11283.8 KXX81743.1 - 0.072 13.1 2.9 4.3 7.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) NAP PF00956.18 KXX81744.1 - 3e-100 334.9 6.6 3e-100 334.9 6.6 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Striatin PF08232.12 KXX81744.1 - 0.047 14.3 0.5 0.047 14.3 0.5 2.7 2 1 0 2 2 2 0 Striatin family RNA_pol_Rpc4 PF05132.14 KXX81744.1 - 3 8.3 0.0 3 8.3 0.0 3.5 2 2 0 3 3 3 0 RNA polymerase III RPC4 Nop14 PF04147.12 KXX81744.1 - 7.7 4.6 25.4 0.28 9.4 18.8 1.7 2 0 0 2 2 2 0 Nop14-like family P5-ATPase PF12409.8 KXX81745.1 - 4.6e-41 139.8 0.1 1e-40 138.7 0.1 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KXX81745.1 - 1.5e-30 106.1 0.0 4.1e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXX81745.1 - 6e-15 56.1 0.2 2.4e-08 34.5 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KXX81745.1 - 3.5e-05 23.6 3.3 3.5e-05 23.6 3.3 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KXX81745.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXX81745.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) CMAS PF02353.20 KXX81746.1 - 3.6e-43 147.8 0.6 6.5e-43 147.0 0.6 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXX81746.1 - 4e-15 56.2 0.0 7.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX81746.1 - 5.2e-14 52.7 0.0 9.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX81746.1 - 2.9e-12 46.6 0.0 4.3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX81746.1 - 1.6e-10 41.0 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX81746.1 - 3e-09 37.5 0.0 6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXX81746.1 - 2.5e-07 30.3 0.0 6e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXX81746.1 - 3.8e-06 26.5 0.0 6.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXX81746.1 - 0.00029 20.2 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KXX81746.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KXX81746.1 - 0.04 13.2 0.0 0.068 12.5 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KXX81746.1 - 0.047 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 KXX81746.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Zwilch PF09817.9 KXX81746.1 - 0.22 9.9 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 RZZ complex, subunit zwilch Pkinase PF00069.25 KXX81747.1 - 9.4e-66 221.9 0.0 1.1e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81747.1 - 4.7e-29 101.5 0.0 6.3e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX81747.1 - 0.0026 17.1 0.0 0.0075 15.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXX81747.1 - 0.024 13.6 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KXX81747.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UCH PF00443.29 KXX81748.1 - 2.8e-30 105.7 0.0 1.4e-29 103.3 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX81748.1 - 1.6e-05 24.7 0.1 0.00017 21.3 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Octopine_DH PF02317.17 KXX81748.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Fungal_trans PF04082.18 KXX81750.1 - 4.1e-27 94.9 0.1 1.4e-26 93.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX81750.1 - 2.2e-10 40.5 11.5 3.7e-10 39.8 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP-alpha_N PF04086.13 KXX81750.1 - 1.1 9.2 7.1 1.2 9.0 0.8 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal HCO3_cotransp PF00955.21 KXX81751.1 - 1.8e-84 284.4 13.8 1.8e-44 152.5 5.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family Serglycin PF04360.12 KXX81751.1 - 0.0077 16.2 3.3 0.015 15.2 3.3 1.4 1 0 0 1 1 1 1 Serglycin SEEEED PF14797.6 KXX81751.1 - 0.7 10.1 5.0 1.1 9.5 5.0 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Peptidase_M41 PF01434.18 KXX81752.1 - 1.2e-67 227.4 0.0 1.2e-67 227.4 0.0 2.0 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 KXX81752.1 - 5.1e-43 146.6 0.0 1.8e-42 144.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX81752.1 - 3e-10 39.7 0.6 7.4e-10 38.5 0.6 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KXX81752.1 - 5.9e-10 39.5 0.0 1.3e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular Pex14_N PF04695.13 KXX81752.1 - 0.00036 21.2 24.6 0.00041 21.0 22.7 1.9 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_5 PF07728.14 KXX81752.1 - 0.002 18.2 0.0 0.0088 16.0 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DDHD PF02862.17 KXX81752.1 - 0.0028 17.8 4.7 0.0049 17.1 4.7 1.3 1 0 0 1 1 1 1 DDHD domain AAA_22 PF13401.6 KXX81752.1 - 0.009 16.3 0.0 0.61 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXX81752.1 - 0.011 15.5 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXX81752.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KXX81752.1 - 0.017 14.9 0.0 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein Presenilin PF01080.17 KXX81752.1 - 0.026 13.3 17.5 0.037 12.8 17.5 1.1 1 0 0 1 1 1 0 Presenilin AAA_2 PF07724.14 KXX81752.1 - 0.043 13.9 3.5 0.098 12.8 0.0 2.7 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) Hydin_ADK PF17213.3 KXX81752.1 - 0.045 14.0 9.0 0.029 14.6 6.3 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 KXX81752.1 - 0.06 13.7 0.1 0.06 13.7 0.1 3.4 3 1 0 4 4 2 0 AAA ATPase domain ALMT PF11744.8 KXX81752.1 - 0.063 12.1 7.2 0.098 11.5 7.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 KXX81752.1 - 0.081 12.9 35.3 0.13 12.2 35.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 KXX81752.1 - 0.14 11.0 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Otopetrin RR_TM4-6 PF06459.12 KXX81752.1 - 0.2 11.4 19.1 0.34 10.7 19.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 KXX81752.1 - 0.44 10.3 21.3 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ndc1_Nup PF09531.10 KXX81752.1 - 0.5 9.0 8.9 0.81 8.3 8.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec62 PF03839.16 KXX81752.1 - 1.3 8.4 9.8 2.6 7.5 9.8 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Velvet PF11754.8 KXX81752.1 - 1.5 8.7 14.8 2.5 8.0 14.8 1.2 1 0 0 1 1 1 0 Velvet factor AAA_17 PF13207.6 KXX81752.1 - 1.8 9.0 0.0 1.8 9.0 0.0 3.3 3 0 0 3 3 2 0 AAA domain PPP4R2 PF09184.11 KXX81752.1 - 1.9 8.0 14.9 2.9 7.4 14.9 1.2 1 0 0 1 1 1 0 PPP4R2 DUF5427 PF10310.9 KXX81752.1 - 1.9 7.3 20.8 2.9 6.7 20.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Hid1 PF12722.7 KXX81752.1 - 2 6.4 15.2 2.8 6.0 15.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KXX81752.1 - 2.1 6.5 17.8 3.1 6.0 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 KXX81752.1 - 2.3 7.6 16.7 4.2 6.7 16.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 KXX81752.1 - 3.1 6.7 9.9 5 6.0 9.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 KXX81752.1 - 3.3 5.9 28.4 4.9 5.3 28.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.11 KXX81752.1 - 4 6.8 7.5 6.1 6.2 7.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 KXX81752.1 - 4.5 6.7 24.3 8 5.9 24.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AAA_28 PF13521.6 KXX81752.1 - 4.7 7.4 8.8 2.1 8.6 0.0 3.1 2 0 0 2 2 1 0 AAA domain Raftlin PF15250.6 KXX81752.1 - 4.9 5.8 14.5 8 5.1 14.5 1.2 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.8 KXX81752.1 - 5.2 5.7 16.0 9.5 4.9 16.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.13 KXX81752.1 - 5.4 5.9 23.7 8.7 5.2 23.7 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 KXX81752.1 - 6 6.2 27.9 9.8 5.5 27.3 1.6 2 0 0 2 2 1 0 Cobalamin biosynthesis protein CobT CPSF100_C PF13299.6 KXX81752.1 - 6.5 6.9 12.3 15 5.7 12.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal UPF0560 PF10577.9 KXX81752.1 - 7 5.0 20.3 11 4.4 20.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.16 KXX81752.1 - 7.7 6.5 14.3 14 5.6 14.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCDC53 PF10152.9 KXX81752.1 - 8.1 6.8 18.4 25 5.2 18.4 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Zip PF02535.22 KXX81752.1 - 8.7 5.5 11.0 13 4.9 11.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.14 KXX81752.1 - 8.8 6.2 24.6 2.5 8.0 21.5 1.6 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) IF-2B PF01008.17 KXX81754.1 - 7.3e-44 150.1 0.0 1.6e-43 149.0 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_S24 PF00717.23 KXX81755.1 - 4.7e-08 32.9 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXX81755.1 - 3e-06 27.1 0.0 8.2e-05 22.4 0.0 2.5 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Catalase PF00199.19 KXX81756.1 - 5.2e-152 506.4 0.1 6.5e-152 506.1 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXX81756.1 - 2.8e-15 56.2 0.1 5.5e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive HAUS4 PF14735.6 KXX81757.1 - 0.18 11.5 0.1 0.26 10.9 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Secretin_N_2 PF07655.13 KXX81757.1 - 0.53 10.9 6.4 1.1 9.8 6.4 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain VIR_N PF15912.5 KXX81757.1 - 3.1 7.3 8.7 6.3 6.3 8.7 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Macoilin PF09726.9 KXX81757.1 - 4.6 5.7 6.5 5.3 5.5 6.5 1.1 1 0 0 1 1 1 0 Macoilin family Alb1 PF09135.11 KXX81758.1 - 1.9e-29 102.6 12.3 1.9e-29 102.6 12.3 1.8 2 0 0 2 2 2 1 Alb1 bZIP_1 PF00170.21 KXX81759.1 - 8.3e-09 35.4 5.3 1.5e-08 34.6 5.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXX81759.1 - 9.5e-06 25.6 3.1 9.5e-06 25.6 3.1 1.8 2 0 0 2 2 2 1 Basic region leucine zipper NAM-associated PF14303.6 KXX81759.1 - 0.022 15.5 10.3 0.037 14.8 10.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Rep_fac-A_3 PF08661.11 KXX81760.1 - 3e-22 79.0 0.1 3.2e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF1522 PF07482.11 KXX81760.1 - 0.072 13.4 0.2 0.13 12.6 0.2 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1522) GATA PF00320.27 KXX81761.1 - 0.00013 21.5 3.3 0.013 15.1 0.5 2.4 2 0 0 2 2 2 2 GATA zinc finger zf-RING_7 PF02591.15 KXX81761.1 - 0.21 11.8 0.1 0.55 10.5 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain Pyr_redox_2 PF07992.14 KXX81762.1 - 1.6e-30 106.4 0.0 2.8e-30 105.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX81762.1 - 9.2e-13 48.6 0.0 1.4e-10 41.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX81762.1 - 0.00098 19.1 1.4 1.2 9.1 0.0 4.1 2 2 2 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXX81762.1 - 0.0037 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 KXX81762.1 - 0.076 13.3 0.1 5.1 7.4 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 KXX81762.1 - 0.092 12.0 0.3 7.8 5.7 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Sacchrp_dh_NADP PF03435.18 KXX81762.1 - 0.096 12.9 0.1 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PBP PF01161.20 KXX81764.1 - 5e-15 56.0 0.0 6.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_C78 PF07910.13 KXX81765.1 - 1.9e-66 223.6 0.0 2.4e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C47 PF05543.13 KXX81765.1 - 0.046 13.3 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Staphopain peptidase C47 DCP2 PF05026.13 KXX81766.1 - 0.17 12.2 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Dcp2, box A domain AAA_18 PF13238.6 KXX81767.1 - 6.2e-27 94.7 0.3 1.2e-26 93.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXX81767.1 - 5.6e-08 33.3 0.1 3.4e-07 30.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 KXX81767.1 - 2.5e-05 24.4 0.1 0.024 14.7 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_33 PF13671.6 KXX81767.1 - 2.6e-05 24.4 0.0 0.0017 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KXX81767.1 - 0.00022 21.6 0.0 0.00067 20.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXX81767.1 - 0.00042 20.6 0.5 0.00067 19.9 0.5 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KXX81767.1 - 0.0026 17.9 0.2 0.015 15.5 0.2 1.9 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 KXX81767.1 - 0.0051 17.1 0.6 0.013 15.7 0.6 2.0 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KXX81767.1 - 0.0091 15.9 2.3 0.78 9.6 0.1 2.2 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 KXX81767.1 - 0.0093 16.4 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Hydin_ADK PF17213.3 KXX81767.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain KTI12 PF08433.10 KXX81767.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 KXX81767.1 - 0.016 15.2 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 NTPase Thymidylate_kin PF02223.17 KXX81767.1 - 0.032 13.9 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Cytidylate_kin2 PF13189.6 KXX81767.1 - 0.044 13.9 0.0 0.066 13.3 0.0 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_5 PF07728.14 KXX81767.1 - 0.062 13.3 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXX81767.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 KXX81767.1 - 0.12 12.2 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KXX81767.1 - 0.14 11.8 1.4 0.38 10.4 0.2 2.2 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXX81767.1 - 0.77 9.4 3.5 12 5.6 0.0 2.6 2 1 1 3 3 3 0 AAA domain Ham1p_like PF01725.16 KXX81768.1 - 2.8e-57 193.7 0.0 3.2e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family WAPL PF07814.13 KXX81769.1 - 9.3e-77 258.3 0.3 1.5e-76 257.6 0.3 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 KXX81770.1 - 4.3e-80 268.0 0.0 5.5e-80 267.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXX81770.1 - 0.0032 17.0 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ras PF00071.22 KXX81771.1 - 9e-45 152.2 0.0 1e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX81771.1 - 7.2e-16 58.5 0.0 1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX81771.1 - 7.1e-07 28.8 0.0 8.6e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXX81771.1 - 3.1e-05 23.6 0.0 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX81771.1 - 0.00021 21.4 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXX81771.1 - 0.00096 18.6 0.0 0.0026 17.2 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXX81771.1 - 0.0023 17.9 0.1 0.32 10.9 0.0 2.2 1 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KXX81771.1 - 0.02 14.4 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.6 KXX81771.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 KXX81772.1 - 2.2e-258 859.0 0.0 3.4e-258 858.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KXX81772.1 - 5.6e-27 94.1 2.6 3.2e-26 91.6 2.6 2.5 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 KXX81772.1 - 1.1e-14 52.7 34.2 1.4e-06 27.6 0.9 6.9 6 0 0 6 6 6 4 IQ calmodulin-binding motif GAS PF13851.6 KXX81772.1 - 7.2e-05 22.2 11.6 7.2e-05 22.2 11.6 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Myosin_N PF02736.19 KXX81772.1 - 0.00049 19.9 0.5 0.0012 18.7 0.5 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain FlaC_arch PF05377.11 KXX81772.1 - 0.0085 16.5 9.3 0.025 15.0 0.2 4.0 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) AAA_22 PF13401.6 KXX81772.1 - 0.011 16.0 0.0 0.041 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain CALCOCO1 PF07888.11 KXX81772.1 - 0.051 12.4 26.1 0.1 11.4 26.1 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HSF_DNA-bind PF00447.17 KXX81772.1 - 0.095 13.3 0.5 0.38 11.4 0.5 2.1 1 0 0 1 1 1 0 HSF-type DNA-binding AAA_16 PF13191.6 KXX81772.1 - 0.1 13.0 3.3 0.23 11.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain APG6_N PF17675.1 KXX81772.1 - 0.11 13.0 32.8 0.04 14.5 24.9 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TsaE PF02367.17 KXX81772.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF812 PF05667.11 KXX81772.1 - 0.13 11.1 26.5 0.23 10.3 26.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KXX81772.1 - 0.16 12.4 31.6 0.032 14.7 11.8 3.0 2 1 1 3 3 3 0 Fez1 Hemerythrin PF01814.23 KXX81772.1 - 0.38 11.4 6.7 0.32 11.6 4.4 2.1 2 0 0 2 2 1 0 Hemerythrin HHE cation binding domain Baculo_PEP_C PF04513.12 KXX81772.1 - 0.61 10.1 7.7 3.6 7.6 7.7 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.9 KXX81772.1 - 2.8 8.2 11.5 0.36 11.1 6.2 2.3 2 0 0 2 2 1 0 Zinc finger-containing protein EMP24_GP25L PF01105.24 KXX81772.1 - 6.4 6.7 9.1 77 3.1 9.1 2.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TolA_bind_tri PF16331.5 KXX81772.1 - 9 6.5 21.2 0.96 9.6 5.5 4.0 1 1 2 3 3 3 0 TolA binding protein trimerisation DegQ PF08181.11 KXX81772.1 - 9.8 6.4 7.1 1 9.5 0.3 2.9 2 0 0 2 2 1 0 DegQ (SacQ) family tRNA-synt_2b PF00587.25 KXX81773.1 - 2.2e-38 132.0 0.0 3.5e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXX81773.1 - 5.9e-19 68.3 5.5 1.2e-18 67.3 5.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TssO PF17561.2 KXX81773.1 - 0.089 12.9 1.1 0.19 11.8 1.1 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO Peptidase_C54 PF03416.19 KXX81773.1 - 0.098 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C54 2-Hacid_dh_C PF02826.19 KXX81774.1 - 2.3e-52 176.9 0.0 3.7e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXX81774.1 - 8.8e-39 132.2 0.1 1.2e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXX81774.1 - 2.7e-05 24.4 0.1 6.1e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 KXX81774.1 - 0.0014 18.3 0.1 0.0044 16.8 0.1 1.9 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 KXX81774.1 - 0.0017 17.9 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KXX81774.1 - 0.0027 17.8 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KXX81774.1 - 0.026 15.0 0.0 0.092 13.3 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Cyt-b5 PF00173.28 KXX81775.1 - 2.4e-20 72.5 0.2 2.6e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EMP24_GP25L PF01105.24 KXX81777.1 - 2.8e-40 138.2 0.0 3.3e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KXX81777.1 - 0.013 13.7 0.4 0.016 13.4 0.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF5521 PF17659.1 KXX81778.1 - 9.4 3.9 5.8 19 2.9 5.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MIS13 PF08202.11 KXX81779.1 - 4.1e-61 206.9 0.0 8.4e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF2981 PF11200.8 KXX81779.1 - 0.83 9.3 2.2 1.4 8.6 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Chitin_synth_1 PF01644.17 KXX81780.1 - 4.2e-70 235.0 0.0 7.2e-70 234.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXX81780.1 - 1.7e-27 95.1 0.1 3e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXX81780.1 - 2e-25 89.4 0.0 2.1e-21 76.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXX81780.1 - 2.2e-06 27.7 9.5 2.2e-06 27.7 9.5 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 IlvN PF07991.12 KXX81781.1 - 1.4e-46 158.1 0.0 2.2e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KXX81781.1 - 7.4e-41 139.8 0.0 1.1e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KXX81781.1 - 0.045 14.3 0.0 0.14 12.8 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Phage_holin_2_4 PF16082.5 KXX81782.1 - 0.21 11.4 0.7 0.83 9.4 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Glyco_hydro_16 PF00722.21 KXX81783.1 - 2.4e-05 23.9 0.0 2.4e-05 23.9 0.0 3.1 4 0 0 4 4 4 1 Glycosyl hydrolases family 16 TPR_1 PF00515.28 KXX81784.1 - 1.2e-09 37.5 2.3 0.03 14.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXX81784.1 - 2.2e-09 37.5 9.8 7.4e-05 23.0 0.2 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXX81784.1 - 2e-07 30.7 2.7 3.1e-05 23.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXX81784.1 - 6.4e-07 29.0 7.8 0.0018 18.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXX81784.1 - 8.3e-07 28.6 7.6 0.021 14.8 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXX81784.1 - 0.011 15.5 3.8 0.67 9.7 0.0 3.7 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 KXX81784.1 - 0.024 14.8 6.5 1.6 9.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXX81784.1 - 0.04 14.6 3.9 5.4 7.7 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat SNAP PF14938.6 KXX81784.1 - 0.052 13.0 1.0 0.15 11.4 0.1 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KXX81784.1 - 0.26 12.0 1.4 8.2 7.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX81784.1 - 0.41 11.6 7.1 11 7.1 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KXX81784.1 - 1.8 8.7 8.5 3.6 7.7 0.7 4.0 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain bZIP_1 PF00170.21 KXX81785.1 - 9.3e-06 25.7 7.5 9.3e-06 25.7 7.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXX81785.1 - 3.1e-05 24.0 6.7 3.1e-05 24.0 6.7 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXX81785.1 - 0.017 15.7 7.5 0.017 15.7 7.5 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor PKcGMP_CC PF16808.5 KXX81785.1 - 0.035 14.0 0.6 0.058 13.3 0.6 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SHE3 PF17078.5 KXX81785.1 - 0.037 13.7 3.0 0.057 13.1 3.0 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 BCL9 PF11502.8 KXX81785.1 - 0.092 12.6 1.0 0.19 11.5 1.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Dicty_REP PF05086.12 KXX81785.1 - 0.29 9.1 0.6 0.33 8.9 0.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sugarporin_N PF11471.8 KXX81785.1 - 0.34 10.9 0.1 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF3433 PF11915.8 KXX81786.1 - 2.1e-38 130.7 11.0 9.9e-21 74.0 2.1 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Pho86 PF11124.8 KXX81786.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 TRP PF06011.12 KXX81787.1 - 4.3e-164 546.3 27.7 5e-164 546.1 27.7 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXX81787.1 - 1.1e-42 145.6 0.6 1.1e-42 145.6 0.6 1.6 2 0 0 2 2 2 1 ML-like domain DUF4079 PF13301.6 KXX81787.1 - 1.3 9.2 15.7 3.4 7.8 2.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF4579 PF15158.6 KXX81787.1 - 5.4 6.7 6.1 1 9.1 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4579) Peptidase_M48 PF01435.18 KXX81788.1 - 1.3e-37 129.5 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Ras PF00071.22 KXX81789.1 - 1.5e-14 54.0 0.0 5.2e-09 35.9 0.0 2.7 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KXX81789.1 - 0.016 15.4 0.1 0.084 13.1 0.0 2.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KXX81789.1 - 0.077 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KXX81789.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXX81789.1 - 0.2 11.1 0.1 0.73 9.3 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region zf-U1 PF06220.12 KXX81790.1 - 1.6e-21 75.8 3.8 2.4e-21 75.2 3.8 1.3 1 0 0 1 1 1 1 U1 zinc finger NicO PF03824.16 KXX81791.1 - 0.015 14.7 1.7 0.021 14.2 1.7 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SpoIIIAH PF12685.7 KXX81791.1 - 0.051 13.4 1.2 0.058 13.2 1.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SR-25 PF10500.9 KXX81791.1 - 0.15 11.7 15.5 0.2 11.3 15.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KXX81791.1 - 0.3 10.7 9.3 0.39 10.4 9.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 HNF-1_N PF04814.13 KXX81791.1 - 0.51 10.9 9.4 0.61 10.7 9.4 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Macoilin PF09726.9 KXX81791.1 - 1.3 7.5 8.1 1.4 7.4 8.1 1.0 1 0 0 1 1 1 0 Macoilin family BES1_N PF05687.13 KXX81791.1 - 3.6 8.0 13.3 3.5 8.0 12.6 1.3 1 1 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal FAM76 PF16046.5 KXX81791.1 - 3.8 6.8 9.3 4.8 6.4 9.3 1.1 1 0 0 1 1 1 0 FAM76 protein ASD2 PF08687.11 KXX81791.1 - 9.3 5.7 5.4 12 5.4 5.4 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 HD PF01966.22 KXX81793.1 - 4.1e-05 23.8 0.1 0.00022 21.5 0.0 2.0 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 KXX81793.1 - 0.029 13.8 0.0 0.057 12.9 0.0 1.5 1 1 0 1 1 1 0 HDOD domain SUR7 PF06687.12 KXX81794.1 - 5.7e-33 114.3 20.7 6.8e-33 114.1 20.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Sdh5 PF03937.16 KXX81795.1 - 2.6e-24 84.9 0.1 1.4e-23 82.7 0.1 1.9 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase IDO PF01231.18 KXX81796.1 - 2e-32 112.5 0.0 2.6e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TipAS PF07739.13 KXX81796.1 - 0.066 13.8 0.0 0.56 10.8 0.0 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain PALP PF00291.25 KXX81797.1 - 1.7e-58 198.3 1.4 2e-58 198.1 1.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ras PF00071.22 KXX81798.1 - 3.1e-51 173.2 0.0 5.9e-51 172.3 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXX81798.1 - 3.3e-18 66.0 0.0 5.1e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX81798.1 - 0.0005 19.6 0.0 0.0013 18.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXX81798.1 - 0.021 14.7 0.0 7 6.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KXX81798.1 - 0.056 13.0 0.1 0.81 9.2 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF2075 PF09848.9 KXX81798.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KXX81798.1 - 0.11 12.9 0.1 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KXX81798.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KXX81798.1 - 0.18 11.9 0.1 0.54 10.3 0.1 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Opy2 PF09463.10 KXX81799.1 - 1.2e-05 25.5 16.1 2e-05 24.8 16.1 1.3 1 0 0 1 1 1 1 Opy2 protein UQ_con PF00179.26 KXX81800.1 - 7.4e-37 126.1 0.0 9.9e-37 125.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX81800.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B AMPK1_CBM PF16561.5 KXX81801.1 - 5.5e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 KXX81801.1 - 0.014 15.2 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Starch binding domain zf-PHD-like PF15446.6 KXX81803.1 - 1.8e-69 232.7 12.1 1.8e-69 232.7 12.1 1.9 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KXX81803.1 - 1.7e-51 175.0 0.0 2.7e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX81803.1 - 1.1e-18 67.6 0.0 7.8e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX81803.1 - 4.4e-07 30.1 0.0 1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXX81803.1 - 2.5e-05 23.6 0.4 7.6e-05 22.0 0.4 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 KXX81803.1 - 0.00014 21.7 6.4 0.00014 21.7 6.4 3.4 2 2 1 3 3 2 1 PHD-finger Chromo PF00385.24 KXX81803.1 - 0.0017 18.2 4.9 0.0077 16.1 1.0 3.2 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 KXX81803.1 - 0.0029 17.4 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1087 PF06465.13 KXX81803.1 - 0.023 14.7 0.1 0.063 13.3 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) AAA_22 PF13401.6 KXX81803.1 - 0.029 14.7 0.0 0.13 12.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain Zf_RING PF16744.5 KXX81803.1 - 6.9 6.9 12.3 3.7 7.7 4.8 2.7 2 1 0 2 2 2 0 KIAA1045 RING finger PCI PF01399.27 KXX81805.1 - 0.009 16.5 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain cwf21 PF08312.12 KXX81805.1 - 0.073 13.2 0.3 0.14 12.3 0.3 1.5 1 0 0 1 1 1 0 cwf21 domain Rep_fac-A_C PF08646.10 KXX81806.1 - 2.3e-57 192.8 2.6 1.2e-55 187.2 1.0 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KXX81806.1 - 6.1e-39 131.9 1.1 4.1e-38 129.2 0.5 2.3 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KXX81806.1 - 2.5e-19 69.2 0.0 6.3e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KXX81806.1 - 1.5e-17 63.3 2.1 7.2e-12 45.1 0.0 4.6 4 1 1 5 5 5 3 OB-fold nucleic acid binding domain DUF4539 PF15072.6 KXX81806.1 - 0.0016 18.4 0.3 0.54 10.3 0.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4539) CDC24_OB3 PF17244.2 KXX81806.1 - 0.0044 16.8 3.7 0.027 14.2 0.1 3.1 4 0 0 4 4 4 1 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 KXX81806.1 - 0.0068 14.3 0.1 0.012 13.5 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5521) zf-like PF04071.12 KXX81806.1 - 0.037 13.9 0.3 0.088 12.7 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain Amidohydro_2 PF04909.14 KXX81807.1 - 1.7e-25 90.4 0.2 2.2e-25 90.1 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Clc-like PF07062.12 KXX81807.1 - 0.17 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Clc-like SpoU_methylase PF00588.19 KXX81809.1 - 1.5e-28 99.8 0.0 2.7e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KXX81809.1 - 1.6e-09 37.9 0.0 5.9e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding TMV_coat PF00721.21 KXX81809.1 - 0.1 12.4 0.5 0.2 11.5 0.5 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) Lin-8 PF03353.15 KXX81810.1 - 3.4 7.2 5.6 5.3 6.5 5.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SUR7 PF06687.12 KXX81812.1 - 2e-21 76.6 9.5 2.4e-21 76.4 9.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family MFS_MOT1 PF16983.5 KXX81814.1 - 5.8e-62 207.0 33.1 2.9e-34 117.8 14.7 2.3 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KXX81814.1 - 5.2e-06 25.5 0.2 5.2e-06 25.5 0.2 2.5 2 1 0 2 2 2 2 Sulfate permease family Bromodomain PF00439.25 KXX81815.1 - 4.4e-24 84.4 0.2 7.6e-24 83.6 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXX81815.1 - 1.7e-07 31.5 0.0 3.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX81815.1 - 9.1e-07 28.9 0.3 1.9e-06 27.9 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX81815.1 - 0.00061 20.2 0.1 0.0013 19.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Forkhead PF00250.18 KXX81816.1 - 1.9e-14 53.7 0.0 3.5e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXX81816.1 - 2.3e-06 27.9 0.0 4.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Saf_2TM PF18303.1 KXX81817.1 - 0.33 10.5 1.2 0.64 9.6 1.1 1.6 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain Aft1_HRR PF11787.8 KXX81818.1 - 2.4e-29 102.3 6.0 2.4e-29 102.3 6.0 3.7 3 1 0 3 3 2 1 Aft1 HRR domain Aft1_HRA PF11786.8 KXX81818.1 - 3.6e-25 88.1 9.0 3.6e-25 88.1 9.0 3.1 3 1 0 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.8 KXX81818.1 - 3.8e-23 81.7 12.0 3.8e-23 81.7 12.0 4.8 5 1 0 5 5 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KXX81818.1 - 1.8e-12 47.1 6.5 3.5e-12 46.3 6.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXX81818.1 - 6.9e-06 26.1 7.4 1.6e-05 24.9 7.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXX81818.1 - 0.0038 17.7 3.9 0.0038 17.7 3.9 2.2 3 0 0 3 3 3 1 bZIP Maf transcription factor FAM76 PF16046.5 KXX81818.1 - 0.066 12.6 7.3 0.15 11.4 7.3 1.6 1 0 0 1 1 1 0 FAM76 protein ZapB PF06005.12 KXX81818.1 - 0.14 12.6 0.4 0.14 12.6 0.4 1.7 2 0 0 2 2 1 0 Cell division protein ZapB Tmemb_cc2 PF10267.9 KXX81818.1 - 0.2 10.8 5.8 0.34 10.0 5.8 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3450 PF11932.8 KXX81818.1 - 0.34 10.2 4.6 1.2 8.4 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 KXX81818.1 - 0.36 10.6 1.4 0.71 9.7 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 KXX81818.1 - 0.54 8.7 7.9 0.83 8.1 7.9 1.2 1 0 0 1 1 1 0 Macoilin family Nnf1 PF03980.14 KXX81818.1 - 3.5 8.0 7.5 0.42 11.0 1.9 2.4 2 0 0 2 2 2 0 Nnf1 GST_N_3 PF13417.6 KXX81819.1 - 1.1e-12 48.2 0.8 1.8e-12 47.4 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX81819.1 - 3.2e-06 27.1 0.2 6.8e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXX81819.1 - 4.4e-06 26.9 0.0 8.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXX81819.1 - 0.093 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Transferase PF02458.15 KXX81820.1 - 1.6e-16 60.0 0.0 3.5e-16 58.9 0.0 1.4 2 0 0 2 2 2 1 Transferase family CPSase_L_D2 PF02786.17 KXX81821.1 - 1.8e-113 377.3 0.2 4.5e-84 281.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KXX81821.1 - 9.2e-46 154.8 0.0 2e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KXX81821.1 - 2.7e-45 154.5 0.0 5.2e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KXX81821.1 - 3.2e-44 150.5 0.0 7.9e-44 149.3 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KXX81821.1 - 3.7e-39 133.8 0.0 1.2e-38 132.2 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KXX81821.1 - 9e-27 94.1 0.0 2.2e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KXX81821.1 - 1.7e-20 73.0 0.0 8.7e-20 70.7 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 KXX81821.1 - 1.6e-17 63.6 0.1 3.4e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXX81821.1 - 1.7e-17 63.6 1.1 6.9e-08 32.3 0.1 2.7 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KXX81821.1 - 9.3e-11 41.6 0.0 3e-05 23.8 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KXX81821.1 - 3.1e-05 24.1 0.4 0.13 12.3 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 KXX81821.1 - 3.5e-05 23.7 0.4 0.0046 16.8 0.4 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 KXX81821.1 - 6.5e-05 22.8 0.1 0.68 9.7 0.0 3.3 3 1 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 KXX81821.1 - 0.0018 18.1 0.0 0.21 11.4 0.0 3.7 4 0 0 4 4 4 1 DJ-1/PfpI family Ion_trans PF00520.31 KXX81822.1 - 7.7e-09 35.1 23.3 1.3e-08 34.4 23.3 1.3 1 0 0 1 1 1 1 Ion transport protein COMP PF11598.8 KXX81823.1 - 0.16 12.5 0.1 0.26 11.8 0.1 1.2 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein PapA_C PF16911.5 KXX81824.1 - 0.0038 17.3 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus MFS_1 PF07690.16 KXX81825.1 - 1.2e-34 119.8 46.4 1.2e-34 119.8 46.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX81825.1 - 2.8e-09 36.3 14.1 2.8e-09 36.3 14.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter FSH1 PF03959.13 KXX81826.1 - 2.8e-32 112.1 0.0 3.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXX81826.1 - 1.7e-05 25.5 0.9 2.5e-05 25.0 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX81826.1 - 2e-05 24.5 0.0 0.00036 20.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PE-PPE PF08237.11 KXX81826.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_3 PF07859.13 KXX81826.1 - 0.13 12.1 0.3 0.33 10.8 0.3 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.25 KXX81827.1 - 2.1e-40 138.3 0.0 2.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81827.1 - 9.7e-34 116.9 0.0 1.4e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX81827.1 - 9.6e-14 51.7 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1182 PF06681.13 KXX81827.1 - 0.096 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) DUF1776 PF08643.10 KXX81827.1 - 0.18 11.2 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2717 PF10911.8 KXX81827.1 - 0.19 11.5 0.0 0.65 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) Hydrophobin_2 PF06766.11 KXX81828.1 - 7.2e-25 86.7 9.1 9e-25 86.4 9.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin HeLo PF14479.6 KXX81829.1 - 9.3e-08 32.1 0.6 0.0065 16.3 0.1 2.5 1 1 1 2 2 2 2 Prion-inhibition and propagation Apolipoprotein PF01442.18 KXX81830.1 - 0.03 14.2 33.1 0.035 14.0 0.0 6.1 5 1 1 6 6 6 0 Apolipoprotein A1/A4/E domain DUF842 PF05811.13 KXX81830.1 - 0.41 10.3 1.3 8.4 6.1 0.0 3.5 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF842) MT0933_antitox PF14013.6 KXX81830.1 - 1 9.7 20.4 0.18 12.1 3.7 4.3 3 0 0 3 3 3 0 MT0933-like antitoxin protein RINGv PF12906.7 KXX81831.1 - 2e-16 59.8 9.3 3.4e-16 59.1 9.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXX81831.1 - 0.0088 16.4 8.1 0.015 15.6 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KXX81831.1 - 0.85 9.7 4.5 1.9 8.6 4.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXX81831.1 - 1.6 8.6 7.1 2.8 7.8 7.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXX81831.1 - 3.4 7.9 5.8 6.5 7.0 5.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain FAD_binding_4 PF01565.23 KXX81832.1 - 1.4e-20 73.4 4.0 5.7e-18 65.0 4.0 2.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX81832.1 - 4.9e-10 39.4 0.0 1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KXX81833.1 - 4.5e-27 94.9 0.0 6.5e-26 91.1 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 tRNA-synt_1d PF00750.19 KXX81834.1 - 6.4e-99 331.2 1.9 8.4e-99 330.8 1.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KXX81834.1 - 1.8e-27 95.9 1.1 2.9e-27 95.2 0.1 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KXX81834.1 - 2.9e-06 27.8 0.0 1e-05 26.0 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain HetR_C PF18460.1 KXX81834.1 - 0.01 15.8 0.4 20 5.2 0.0 4.1 4 0 0 4 4 4 1 Heterocyst differentiation regulator C-terminal Hood domain SYF2 PF08231.12 KXX81834.1 - 1.6 9.1 7.1 0.22 11.9 3.0 1.6 2 0 0 2 2 2 0 SYF2 splicing factor Ferric_reduct PF01794.19 KXX81835.1 - 6.5e-17 61.8 14.1 7.7e-17 61.6 12.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXX81835.1 - 2.4e-15 56.6 0.0 5.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXX81835.1 - 1.1e-13 51.6 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DNA_PPF PF02916.15 KXX81837.1 - 0.03 14.7 2.3 0.079 13.4 2.3 1.6 1 0 0 1 1 1 0 DNA polymerase processivity factor Phage_F PF02305.17 KXX81837.1 - 0.32 9.7 0.1 0.4 9.4 0.1 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) Dynactin_p62 PF05502.13 KXX81838.1 - 4.7e-218 724.8 0.0 5.8e-218 724.5 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.6 KXX81838.1 - 1.3 9.3 5.7 0.11 12.7 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) zinc_ribbon_10 PF10058.9 KXX81838.1 - 3.8 7.3 0.0 3.8 7.3 0.0 3.6 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein ADH_N PF08240.12 KXX81839.1 - 3.8e-24 84.7 2.0 6.1e-24 84.0 2.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX81839.1 - 4e-13 49.5 0.1 9.8e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXX81839.1 - 4.3e-05 22.9 0.1 7.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXX81839.1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 KXX81839.1 - 0.054 13.8 0.0 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GATase PF00117.28 KXX81840.1 - 2.4e-06 27.4 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C2 PF00648.21 KXX81841.1 - 7.5e-60 202.5 0.3 1.5e-58 198.2 0.3 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Ribosomal_S7e PF01251.18 KXX81843.1 - 3.9e-80 268.0 0.1 4.6e-80 267.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Peptidase_S8 PF00082.22 KXX81844.1 - 3e-44 151.5 0.2 5e-44 150.7 0.2 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXX81844.1 - 2.7e-16 60.3 0.0 5.1e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KXX81844.1 - 1.5e-08 34.6 0.8 7.6e-08 32.3 0.0 2.5 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.6 KXX81844.1 - 2.8e-06 27.1 0.1 9.5e-06 25.4 0.1 1.9 1 0 0 1 1 1 1 FlgD Ig-like domain Glyco_hydro_10 PF00331.20 KXX81845.1 - 5.7e-87 291.8 0.0 6.3e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 SnoaL_2 PF12680.7 KXX81845.1 - 0.11 13.2 0.0 0.41 11.3 0.0 2.1 1 1 0 1 1 1 0 SnoaL-like domain Apolipoprotein PF01442.18 KXX81846.1 - 0.00024 21.0 14.3 0.016 15.1 1.8 3.3 1 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 KXX81846.1 - 0.00036 20.7 1.8 3.2 8.1 0.3 4.2 2 1 3 5 5 5 2 Bacterial protein of unknown function (DUF948) TetR_C_24 PF17932.1 KXX81846.1 - 0.0085 16.3 0.4 0.35 11.2 0.0 3.4 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain Alpha-E PF04168.12 KXX81846.1 - 0.017 14.9 1.0 0.06 13.1 0.0 2.3 3 0 0 3 3 3 0 A predicted alpha-helical domain with a conserved ER motif. Tugs PF17840.1 KXX81846.1 - 0.018 15.2 0.1 0.059 13.6 0.0 1.9 2 0 0 2 2 1 0 Tethering Ubl4a to BAGS domain ApoLp-III PF07464.11 KXX81846.1 - 0.027 14.6 9.6 8.2 6.5 0.3 4.7 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Dynamin_M PF01031.20 KXX81846.1 - 0.048 12.9 1.4 16 4.6 0.0 3.2 2 1 1 3 3 3 0 Dynamin central region DUF3223 PF11523.8 KXX81846.1 - 0.069 14.0 0.5 5.5 7.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3223) YtxH PF12732.7 KXX81846.1 - 0.16 12.5 19.9 12 6.5 5.0 5.3 2 2 0 2 2 2 0 YtxH-like protein Syntaxin_2 PF14523.6 KXX81846.1 - 0.54 10.6 9.3 16 5.9 0.0 4.6 4 1 1 5 5 5 0 Syntaxin-like protein FAM184 PF15665.5 KXX81846.1 - 3 7.6 12.3 0.57 9.9 0.4 3.4 3 1 1 4 4 4 0 Family with sequence similarity 184, A and B DUF2203 PF09969.9 KXX81846.1 - 4.4 8.1 6.0 15 6.4 0.1 3.7 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) CarD_CdnL_TRCF PF02559.16 KXX81846.1 - 7.6 7.3 6.5 1e+02 3.7 0.0 4.3 5 1 1 6 6 6 0 CarD-like/TRCF domain LANC_like PF05147.13 KXX81847.1 - 4.7e-21 74.8 0.0 1.1e-20 73.5 0.0 1.5 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Ribosomal_S7e PF01251.18 KXX81848.1 - 3.9e-80 268.0 0.1 4.6e-80 267.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.12 KXX81850.1 - 3.8e-24 84.7 2.0 6.1e-24 84.0 2.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX81850.1 - 4e-13 49.5 0.1 9.8e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXX81850.1 - 4.3e-05 22.9 0.1 7.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXX81850.1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 KXX81850.1 - 0.054 13.8 0.0 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Dynactin_p62 PF05502.13 KXX81851.1 - 4.7e-218 724.8 0.0 5.8e-218 724.5 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.6 KXX81851.1 - 1.3 9.3 5.7 0.11 12.7 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) zinc_ribbon_10 PF10058.9 KXX81851.1 - 3.8 7.3 0.0 3.8 7.3 0.0 3.6 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Glyco_hydro_59 PF02057.15 KXX81852.1 - 5.2e-14 52.2 3.9 8.9e-14 51.4 3.9 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 KXX81852.1 - 5.7e-12 45.7 5.1 1.4e-10 41.2 6.1 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 KXX81852.1 - 9.5e-10 38.6 4.5 3.5e-08 33.4 0.0 2.2 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 KXX81852.1 - 2.5e-09 36.6 0.2 1.3e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain BolA PF01722.18 KXX81854.1 - 3.9e-10 39.8 0.0 9.3e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Peptidase_S8 PF00082.22 KXX81855.1 - 3e-44 151.5 0.2 5e-44 150.7 0.2 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KXX81855.1 - 2.7e-16 60.3 0.0 5.1e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KXX81855.1 - 1.5e-08 34.6 0.8 7.6e-08 32.3 0.0 2.5 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.6 KXX81855.1 - 2.8e-06 27.1 0.1 9.5e-06 25.4 0.1 1.9 1 0 0 1 1 1 1 FlgD Ig-like domain Peptidase_C2 PF00648.21 KXX81856.1 - 8e-60 202.4 0.3 1.6e-58 198.1 0.3 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease TMEM171 PF15471.6 KXX81856.1 - 1.4 7.8 8.3 3.6 6.5 8.3 1.7 1 0 0 1 1 1 0 Transmembrane protein family 171 GATase PF00117.28 KXX81857.1 - 2.6e-06 27.4 0.0 3.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Glyco_hydro_59 PF02057.15 KXX81859.1 - 4.7e-14 52.3 3.7 8e-14 51.6 3.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 KXX81859.1 - 6.5e-13 48.7 5.7 1.5e-11 44.3 6.4 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 KXX81859.1 - 1.1e-09 38.3 4.7 3.7e-08 33.4 0.0 2.2 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 KXX81859.1 - 2.8e-09 36.4 0.2 1.3e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain BolA PF01722.18 KXX81860.1 - 3.9e-10 39.8 0.0 9.3e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Cofilin_ADF PF00241.20 KXX81862.1 - 2.3e-35 121.0 0.0 2.2e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DIOX_N PF14226.6 KXX81863.1 - 8.4e-05 23.3 0.0 0.0002 22.1 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXX81863.1 - 0.00023 21.6 0.0 0.0004 20.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXX81864.1 - 8.4e-05 23.3 0.0 0.0002 22.1 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXX81864.1 - 0.00023 21.6 0.0 0.0004 20.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cofilin_ADF PF00241.20 KXX81865.1 - 2.3e-35 121.0 0.0 2.2e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Asp PF00026.23 KXX81868.1 - 6.2e-39 134.3 0.0 9.6e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX81868.1 - 0.00014 22.1 0.1 0.00038 20.7 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 KXX81869.1 - 6.2e-39 134.3 0.0 9.6e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX81869.1 - 0.00014 22.1 0.1 0.00038 20.7 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal PMT PF02366.18 KXX81871.1 - 8.4e-84 281.0 16.0 1.6e-83 280.0 16.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXX81871.1 - 6.2e-68 228.3 10.6 6.2e-68 228.3 10.6 2.9 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXX81871.1 - 1e-18 67.9 0.4 1.8e-18 67.1 0.4 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KXX81871.1 - 0.0017 18.6 9.8 0.0017 18.6 9.8 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ammonium_transp PF00909.21 KXX81872.1 - 5.7e-111 371.0 26.3 3.7e-81 272.8 20.6 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family DUF441 PF04284.13 KXX81872.1 - 0.04 13.9 1.8 0.082 12.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF441) DUF373 PF04123.13 KXX81872.1 - 1.1 8.7 6.5 4.5 6.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Peptidase_C15 PF01470.17 KXX81873.1 - 1.6e-11 44.8 0.1 0.00021 21.5 0.0 2.9 2 1 0 2 2 2 2 Pyroglutamyl peptidase IBR PF01485.21 KXX81874.1 - 1.3e-10 41.4 45.1 4.1e-06 26.9 12.5 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-ACC PF17848.1 KXX81874.1 - 0.065 13.3 6.2 0.61 10.2 0.1 3.2 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Filament PF00038.21 KXX81875.1 - 0.0011 18.6 36.9 0.0011 18.6 36.9 6.2 3 2 1 4 4 4 3 Intermediate filament protein FAM184 PF15665.5 KXX81875.1 - 0.0023 17.8 23.9 0.0023 17.8 23.9 4.8 4 1 0 4 4 4 1 Family with sequence similarity 184, A and B FIVAR PF07554.13 KXX81875.1 - 0.51 11.1 2.9 3.1 8.6 0.1 3.5 3 0 0 3 3 3 0 FIVAR domain SWIB PF02201.18 KXX81875.1 - 0.89 9.5 3.3 7.3 6.6 0.2 3.3 3 0 0 3 3 3 0 SWIB/MDM2 domain XPG_N PF00752.17 KXX81877.1 - 2.6e-33 114.5 0.0 5.8e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KXX81877.1 - 4.5e-26 91.0 0.0 1.3e-25 89.6 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KXX81877.1 - 0.00023 20.9 0.6 0.00023 20.9 0.6 3.4 3 0 0 3 3 3 1 Ubiquitin interaction motif XPG_I_2 PF12813.7 KXX81877.1 - 0.00073 19.1 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing CAF1A PF12253.8 KXX81877.1 - 0.062 13.5 0.2 0.062 13.5 0.2 3.9 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A HHH PF00633.23 KXX81877.1 - 0.068 13.1 0.1 0.26 11.2 0.1 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 KXX81877.1 - 0.094 13.3 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Oxidored_FMN PF00724.20 KXX81878.1 - 2.6e-70 237.4 0.0 3.1e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 KXX81879.1 - 1.3e-33 116.4 26.1 1.2e-32 113.2 27.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXX81879.1 - 2e-08 33.9 6.6 1.5e-06 27.8 2.0 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF3185 PF11381.8 KXX81879.1 - 0.044 13.8 0.9 0.2 11.7 0.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) Transmemb_17 PF09799.9 KXX81879.1 - 0.25 11.9 0.0 0.25 11.9 0.0 3.3 3 1 0 3 3 3 0 Predicted membrane protein Mito_carr PF00153.27 KXX81882.1 - 5.6e-59 196.1 2.8 5.8e-20 71.0 0.1 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF1708 PF08101.11 KXX81883.1 - 1.3e-178 594.6 0.0 1.9e-178 594.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.19 KXX81884.1 - 3.3e-23 82.4 0.0 5.4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily CDC27 PF09507.10 KXX81884.1 - 0.062 12.7 0.6 0.062 12.7 0.6 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Metallophos PF00149.28 KXX81885.1 - 1.1e-11 45.6 0.7 2.4e-11 44.6 0.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_transf_28 PF03033.20 KXX81886.1 - 3.9e-20 72.3 0.7 4.2e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXX81886.1 - 1.9e-05 23.7 0.1 3.2e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXX81886.1 - 4.3e-05 23.5 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 KXX81886.1 - 7.7e-05 23.0 0.1 0.00043 20.6 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UIM PF02809.20 KXX81886.1 - 0.52 10.4 21.4 0.2 11.7 3.7 4.5 3 0 0 3 3 3 0 Ubiquitin interaction motif NAD_binding_10 PF13460.6 KXX81887.1 - 1.5e-12 47.8 0.0 4.2e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX81887.1 - 2.1e-08 34.0 0.1 2.6e-07 30.4 0.1 2.3 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXX81887.1 - 1e-06 28.4 0.0 0.0012 18.4 0.0 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Peripla_BP_1 PF00532.21 KXX81887.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family CbiJ PF02571.14 KXX81887.1 - 0.021 14.3 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK DUF4350 PF14258.6 KXX81887.1 - 0.025 15.0 0.1 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) RmlD_sub_bind PF04321.17 KXX81887.1 - 0.086 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 KXX81887.1 - 0.11 12.4 0.1 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 KXX81887.1 - 0.15 12.3 0.4 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PAF-AH_p_II PF03403.13 KXX81888.1 - 2.2e-52 177.8 0.0 8.3e-26 90.4 0.0 3.9 4 0 0 4 4 4 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXX81888.1 - 4.5e-07 29.0 0.0 0.00011 21.3 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KXX81888.1 - 5e-05 24.0 0.5 0.00036 21.2 0.6 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX81888.1 - 0.00012 21.5 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXX81888.1 - 0.00046 19.3 0.0 0.0062 15.6 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase MCPsignal PF00015.21 KXX81890.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mito_carr PF00153.27 KXX81891.1 - 9.4e-50 166.5 8.7 1.1e-18 66.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein vATP-synt_E PF01991.18 KXX81891.1 - 1.3 8.4 3.8 2 7.8 3.8 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit BRCT_2 PF16589.5 KXX81892.1 - 0.0097 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain EFP_N PF08207.12 KXX81892.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Mob1_phocein PF03637.17 KXX81893.1 - 2.2e-43 148.2 0.0 4.6e-43 147.2 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family Methyltransf_25 PF13649.6 KXX81894.1 - 7.4e-13 49.0 0.0 1.9e-12 47.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX81894.1 - 2.5e-12 46.8 0.1 4.2e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXX81894.1 - 9.9e-12 44.8 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXX81894.1 - 9.4e-10 39.0 0.0 2.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXX81894.1 - 6.7e-08 31.8 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 KXX81894.1 - 2.4e-06 27.5 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXX81894.1 - 1.6e-05 24.8 0.1 2.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX81894.1 - 2.3e-05 24.0 0.1 4.4e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXX81894.1 - 4.7e-05 24.1 0.0 0.00013 22.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXX81894.1 - 8.8e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 KXX81894.1 - 0.00029 20.7 0.2 0.00064 19.6 0.2 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_2 PF00891.18 KXX81894.1 - 0.00038 19.8 0.0 0.00072 18.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KXX81894.1 - 0.00095 19.3 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 KXX81894.1 - 0.0029 17.0 0.1 0.005 16.3 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KXX81894.1 - 0.0036 17.3 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 KXX81894.1 - 0.0042 17.0 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KXX81894.1 - 0.0048 16.7 0.2 0.0068 16.2 0.2 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DOT1 PF08123.13 KXX81894.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KXX81894.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 KXX81894.1 - 0.036 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 KXX81894.1 - 0.048 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase RrnaAD PF00398.20 KXX81894.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PGM_PMM_I PF02878.16 KXX81895.1 - 1.4e-17 63.7 0.0 3.6e-08 33.2 0.0 2.8 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KXX81895.1 - 1.1e-12 47.9 2.4 2.5e-12 46.8 1.0 2.4 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KXX81895.1 - 0.0055 17.3 1.0 0.37 11.4 0.6 3.4 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KXX81895.1 - 0.044 14.0 0.1 0.14 12.4 0.1 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III T3SS_ATPase_C PF18269.1 KXX81895.1 - 0.06 13.2 0.0 16 5.4 0.0 2.9 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain ERCC4 PF02732.15 KXX81896.1 - 6.8e-26 91.3 0.0 1.1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KXX81896.1 - 0.00087 19.6 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KXX81896.1 - 0.0076 16.8 0.0 0.025 15.2 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain Lum_binding PF00677.17 KXX81897.1 - 1.6e-45 153.0 0.9 4e-22 78.0 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain zf-C2H2 PF00096.26 KXX81900.1 - 0.0079 16.6 2.7 0.0079 16.6 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KXX81900.1 - 0.035 13.8 0.2 0.035 13.8 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Ribonuc_L-PSP PF01042.21 KXX81901.1 - 3.4e-38 130.4 0.3 4.6e-38 130.0 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Metallophos PF00149.28 KXX81902.1 - 1.1e-34 120.7 0.0 1.7e-34 120.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXX81902.1 - 6.3e-16 58.5 0.0 1.3e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain EZH2_N PF18601.1 KXX81903.1 - 1.1e-31 109.0 0.0 3.4e-31 107.4 0.0 1.9 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 KXX81903.1 - 9.9e-25 85.9 0.4 2.2e-24 84.8 0.4 1.6 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 KXX81903.1 - 2.3e-16 60.7 0.3 1e-15 58.5 0.3 2.2 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 KXX81903.1 - 0.00034 21.0 13.3 0.00034 21.0 13.3 3.3 2 1 2 4 4 4 1 CXC domain WD40 PF00400.32 KXX81904.1 - 4.1e-18 65.4 9.1 6.4e-06 26.8 0.1 9.7 9 0 0 9 9 9 4 WD domain, G-beta repeat SUR7 PF06687.12 KXX81905.1 - 1.3e-34 119.7 11.2 1.6e-34 119.4 11.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family F_actin_cap_B PF01115.17 KXX81906.1 - 3.2e-105 351.1 0.0 3.7e-105 350.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Glyco_transf_22 PF03901.17 KXX81907.1 - 7.9e-43 147.2 19.6 1.1e-42 146.8 19.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Epimerase PF01370.21 KXX81909.1 - 1.4e-18 67.2 0.0 2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXX81909.1 - 1.3e-07 31.1 0.0 1.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXX81909.1 - 3.5e-07 29.9 0.0 4.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXX81909.1 - 0.00084 18.4 0.0 0.0016 17.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pil1 PF13805.6 KXX81910.1 - 2.9e-127 423.7 0.2 3.7e-127 423.3 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KXX81910.1 - 0.27 10.6 3.2 0.23 10.9 0.9 1.8 1 1 1 2 2 2 0 FAM92 protein LSM PF01423.22 KXX81911.1 - 1.1e-10 41.0 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain Glyco_hydro_3_C PF01915.22 KXX81912.1 - 3.6e-67 226.3 0.0 8.5e-67 225.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXX81912.1 - 4.1e-55 187.4 0.0 6.7e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 KXX81912.1 - 6.8e-24 84.4 0.0 1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 KXX81912.1 - 4.8e-20 71.4 0.2 1.1e-19 70.3 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_transf_17 PF04724.13 KXX81913.1 - 4.3e-52 177.3 0.1 2.2e-51 175.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 17 SLT_2 PF13406.6 KXX81913.1 - 0.00075 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain p450 PF00067.22 KXX81914.1 - 3.5e-80 270.0 0.0 4.6e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1506 PF07405.11 KXX81914.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) MCM PF00493.23 KXX81916.1 - 1.6e-100 334.9 1.4 2.8e-100 334.1 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXX81916.1 - 2.9e-39 133.8 0.2 5.3e-39 132.9 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KXX81916.1 - 1e-33 116.8 32.7 1e-33 116.8 32.7 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KXX81916.1 - 9.3e-26 90.1 0.5 2.4e-25 88.8 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXX81916.1 - 4e-15 56.3 0.1 9.3e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXX81916.1 - 1e-07 31.6 0.0 6.1e-06 25.8 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXX81916.1 - 2.1e-06 27.8 0.0 4.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXX81916.1 - 0.0016 18.3 0.0 0.015 15.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXX81916.1 - 0.0025 17.5 0.2 0.017 14.8 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KXX81916.1 - 0.21 12.3 0.5 0.58 10.9 0.5 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 KXX81916.1 - 0.45 9.9 1.9 0.91 8.9 1.9 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Band_7 PF01145.25 KXX81917.1 - 1.8e-23 83.5 7.4 4.4e-23 82.2 7.4 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KXX81917.1 - 4.6e-05 22.7 5.1 6.3e-05 22.2 5.1 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3103 PF11301.8 KXX81917.1 - 0.09 11.6 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) AAA_lid_4 PF17864.1 KXX81917.1 - 0.57 10.0 4.1 0.4 10.5 0.2 2.5 1 1 0 2 2 2 0 RuvB AAA lid domain UCH PF00443.29 KXX81918.1 - 5.4e-46 157.2 0.0 1e-45 156.3 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX81918.1 - 3.2e-11 43.4 0.0 6.6e-10 39.1 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SAE2 PF08573.10 KXX81919.1 - 3e-22 79.8 0.3 7.5e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus CHORD PF04968.12 KXX81920.1 - 0.13 13.1 5.0 0.13 13.0 0.7 2.8 2 1 1 3 3 3 0 CHORD Glyco_transf_8 PF01501.20 KXX81921.1 - 1.5e-11 44.4 0.0 3e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 UcrQ PF02939.16 KXX81922.1 - 7.8e-38 128.3 1.1 9.1e-38 128.1 1.1 1.0 1 0 0 1 1 1 1 UcrQ family DUF1761 PF08570.10 KXX81923.1 - 5e-25 88.2 4.9 6e-25 87.9 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) BRCT_assoc PF12820.7 KXX81923.1 - 0.04 13.8 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT DUF996 PF06195.13 KXX81923.1 - 0.19 12.0 1.8 0.36 11.1 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF996) NIF PF03031.18 KXX81924.1 - 2.4e-56 189.8 0.0 3.3e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Calici_coat PF00915.20 KXX81924.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Calicivirus coat protein IF-2B PF01008.17 KXX81925.1 - 7.4e-38 130.4 0.0 1.4e-37 129.4 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_L7Ae PF01248.26 KXX81926.1 - 1.6e-15 56.6 0.7 1.5e-14 53.5 0.7 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Eapp_C PF10238.9 KXX81926.1 - 0.55 10.3 8.1 0.85 9.7 4.0 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein RPN2_C PF18004.1 KXX81926.1 - 2.7 7.9 22.6 0.27 11.1 12.7 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain ORC_WH_C PF18137.1 KXX81926.1 - 3 7.9 9.2 36 4.4 0.0 2.3 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal UBA PF00627.31 KXX81927.1 - 2.3e-05 24.2 0.0 5.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 KXX81927.1 - 0.0048 17.1 0.3 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 UBX domain zf-C2H2_3rep PF18868.1 KXX81927.1 - 0.044 14.5 1.2 0.044 14.5 1.2 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Cyclin_C PF02984.19 KXX81927.1 - 0.1 12.7 0.2 0.28 11.3 0.2 1.7 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF1258 PF06869.12 KXX81927.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Exonuc_VII_L PF02601.15 KXX81927.1 - 1 8.8 12.2 1.3 8.5 12.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Asp-B-Hydro_N PF05279.11 KXX81927.1 - 1.3 9.0 18.6 1.8 8.6 18.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ArfGap PF01412.18 KXX81927.1 - 1.8 8.7 6.7 3.6 7.7 6.3 1.9 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf RskA PF10099.9 KXX81927.1 - 4.5 7.5 14.9 0.07 13.4 6.6 2.1 3 0 0 3 3 3 0 Anti-sigma-K factor rskA SOBP PF15279.6 KXX81927.1 - 5.1 7.6 8.4 6.3 7.3 8.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 KXX81927.1 - 6.3 5.0 17.1 7.3 4.8 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Motile_Sperm PF00635.26 KXX81928.1 - 3.5e-23 81.5 0.1 7.1e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KXX81928.1 - 0.051 13.8 1.0 0.096 12.9 0.1 1.9 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF4407 PF14362.6 KXX81928.1 - 0.091 12.1 1.0 0.12 11.7 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AMP-binding PF00501.28 KXX81929.1 - 1.4e-88 297.3 0.0 1.7e-88 297.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX81929.1 - 2.9e-19 69.8 0.2 2.8e-18 66.7 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KXX81929.1 - 0.00014 20.8 0.0 0.0011 18.0 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KXX81929.1 - 0.024 14.7 0.2 0.089 12.8 0.0 2.0 2 0 0 2 2 2 0 RTX C-terminal domain HA2 PF04408.23 KXX81930.1 - 2.3e-18 66.4 0.1 2.3e-18 66.4 0.1 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXX81930.1 - 6.4e-17 61.7 0.0 1.4e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXX81930.1 - 8.4e-13 48.6 0.0 2.4e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX81930.1 - 1.4e-06 28.2 0.1 2.9e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXX81930.1 - 9.2e-05 22.7 0.0 0.00028 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXX81930.1 - 0.00023 21.0 1.1 0.00028 20.7 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXX81930.1 - 0.001 19.4 0.2 0.0023 18.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXX81930.1 - 0.0028 17.3 0.2 0.0053 16.4 0.2 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 KXX81930.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 KXX81930.1 - 0.03 13.9 0.6 2.2 7.9 0.1 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KXX81930.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3824 PF12868.7 KXX81931.1 - 0.00072 20.2 9.9 0.00072 20.2 9.9 13.2 7 4 4 11 11 11 3 Domain of unknwon function (DUF3824) Ribosomal_60s PF00428.19 KXX81932.1 - 2.4e-28 98.5 13.4 3e-28 98.2 13.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KXX81932.1 - 0.36 9.2 2.3 0.46 8.9 2.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Phage_holin_6_1 PF09682.10 KXX81932.1 - 1 9.8 5.4 0.74 10.3 0.4 2.1 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2408 PF10303.9 KXX81933.1 - 1.1e-39 136.1 3.9 6.3e-23 81.8 0.1 4.8 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) YCII PF03795.14 KXX81934.1 - 4.1e-08 33.5 0.0 5.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain G-patch PF01585.23 KXX81935.1 - 2e-11 43.6 1.0 5.8e-11 42.1 1.0 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KXX81935.1 - 0.0077 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3246 PF11596.8 KXX81935.1 - 0.04 13.4 1.2 0.077 12.4 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) G-patch_2 PF12656.7 KXX81935.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.6 3 0 0 3 3 3 0 G-patch domain Ecm33 PF12454.8 KXX81936.1 - 2.5e-15 56.3 0.3 5.2e-15 55.3 0.3 1.6 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 KXX81936.1 - 1.7e-05 24.9 0.7 0.26 11.4 0.0 3.9 2 1 1 3 3 3 3 Receptor L domain HABP4_PAI-RBP1 PF04774.15 KXX81937.1 - 0.021 15.7 2.5 0.038 14.8 2.5 1.5 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family CIAPIN1 PF05093.13 KXX81938.1 - 4.1e-42 142.8 4.3 6.4e-42 142.1 4.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KXX81938.1 - 2.6e-37 128.0 0.0 3.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus SpoIIP PF07454.11 KXX81939.1 - 0.0062 16.0 3.7 0.011 15.3 3.7 1.4 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 KXX81939.1 - 0.0085 15.7 33.0 0.017 14.7 33.0 1.4 1 0 0 1 1 1 1 Spt20 family Endostatin PF06482.11 KXX81939.1 - 0.015 14.8 10.0 0.031 13.7 10.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SHE3 PF17078.5 KXX81939.1 - 0.03 14.0 0.6 0.03 14.0 0.6 2.3 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 DUF4763 PF15960.5 KXX81939.1 - 0.061 12.6 0.1 0.061 12.6 0.1 2.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4763) Pex14_N PF04695.13 KXX81939.1 - 0.16 12.6 29.8 0.043 14.5 26.4 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 KXX81939.1 - 0.2 11.7 3.8 0.45 10.5 3.8 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KXX81939.1 - 0.35 9.6 11.1 0.018 13.8 5.9 1.5 2 0 0 2 2 2 0 Presenilin DUF4770 PF15994.5 KXX81939.1 - 0.76 10.0 11.7 1.6 9.0 11.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Band_3_cyto PF07565.13 KXX81939.1 - 1.2 8.9 6.9 0.25 11.1 3.2 1.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EIIBC-GUT_N PF03612.14 KXX81939.1 - 1.6 8.4 6.5 3.6 7.3 6.5 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3464 PF11947.8 KXX81939.1 - 1.7 8.4 10.2 4.3 7.1 10.2 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Tim54 PF11711.8 KXX81939.1 - 2.1 7.1 13.4 0.077 11.8 7.4 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM76 PF16046.5 KXX81939.1 - 7.1 5.9 13.0 35 3.6 13.0 1.9 1 1 0 1 1 1 0 FAM76 protein Med1 PF10744.9 KXX81940.1 - 6e-107 358.3 0.0 7.9e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 KXX81941.1 - 1.8e-43 148.8 0.0 8.3e-41 140.1 0.0 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX81941.1 - 8.2e-22 77.7 0.0 1.8e-21 76.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pex19 PF04614.12 KXX81942.1 - 3.3e-77 259.6 15.1 4.9e-77 259.0 15.1 1.3 1 0 0 1 1 1 1 Pex19 protein family PP2C_C PF07830.13 KXX81942.1 - 0.00098 19.5 3.5 1.8 9.1 0.1 3.6 2 1 1 3 3 3 2 Protein serine/threonine phosphatase 2C, C-terminal domain Ank_2 PF12796.7 KXX81944.1 - 3.2e-33 114.1 0.0 2.6e-13 50.4 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) SesA PF17107.5 KXX81944.1 - 7.5e-32 110.1 0.1 2.4e-31 108.5 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_5 PF13857.6 KXX81944.1 - 4.9e-22 77.7 0.0 2e-08 34.3 0.0 5.8 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX81944.1 - 7.2e-21 74.3 0.0 2.3e-07 31.2 0.0 5.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KXX81944.1 - 7.1e-18 64.2 0.0 0.00054 20.3 0.0 7.2 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KXX81944.1 - 3.6e-17 60.7 0.1 0.085 13.5 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat NACHT PF05729.12 KXX81944.1 - 2e-09 37.6 0.1 2.7e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX81944.1 - 2e-07 31.6 0.3 9.4e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX81944.1 - 0.0012 19.1 0.3 0.018 15.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KXX81944.1 - 0.002 18.5 0.0 0.016 15.6 0.0 2.5 3 0 0 3 3 3 1 RNA helicase FAM196 PF15265.6 KXX81944.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 FAM196 family AAA_14 PF13173.6 KXX81944.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain FCD PF07729.12 KXX81944.1 - 3.6 8.0 8.3 5.9 7.3 0.1 4.0 3 1 1 4 4 4 0 FCD domain WD40 PF00400.32 KXX81945.1 - 2.5e-47 157.9 11.4 2.3e-07 31.4 0.0 8.4 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81945.1 - 1.8e-10 41.0 0.1 0.0014 18.9 0.0 4.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX81945.1 - 9.5e-07 27.8 0.0 0.0019 16.9 0.0 4.0 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXX81945.1 - 0.014 14.1 0.0 0.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like Formyl_trans_N PF00551.19 KXX81946.1 - 2.7e-23 82.7 0.0 3.7e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Rrn6 PF10214.9 KXX81947.1 - 0.00021 20.0 8.9 0.00033 19.3 8.9 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF4646 PF15496.6 KXX81947.1 - 0.00045 20.8 0.0 0.42 11.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4646) DUF2046 PF09755.9 KXX81947.1 - 0.14 11.3 19.3 0.099 11.9 14.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF508 PF04370.12 KXX81947.1 - 0.16 11.7 1.3 0.37 10.5 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Adeno_VII PF03228.14 KXX81947.1 - 1.6 9.3 7.6 4.7 7.9 7.6 1.8 1 0 0 1 1 1 0 Adenoviral core protein VII Ku_C PF03730.14 KXX81947.1 - 5.9 7.7 8.5 68 4.3 0.0 3.1 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm Acetyltransf_1 PF00583.25 KXX81948.1 - 3.5e-12 46.6 0.0 5.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX81948.1 - 1.2e-06 28.5 0.2 1.8e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX81948.1 - 2e-06 27.7 0.1 3.5e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXX81948.1 - 6.4e-06 26.5 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXX81948.1 - 0.025 14.7 0.1 0.041 14.0 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CI-B14_5a PF07347.12 KXX81949.1 - 0.015 15.2 0.2 0.035 14.0 0.0 1.7 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) AhpC-TSA PF00578.21 KXX81950.1 - 4.3e-22 78.4 0.0 6.5e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXX81950.1 - 4e-16 59.0 0.0 6.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KXX81950.1 - 0.0018 18.3 0.0 0.0036 17.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme TT_ORF2 PF02957.15 KXX81950.1 - 7.4 7.5 15.0 0.67 10.9 1.1 2.3 2 0 0 2 2 2 0 TT viral ORF2 adh_short_C2 PF13561.6 KXX81951.1 - 7.1e-47 159.9 0.4 6.8e-39 133.8 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX81951.1 - 1.1e-43 149.0 0.1 1.6e-43 148.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX81951.1 - 3.4e-13 49.9 0.1 5.7e-13 49.2 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX81951.1 - 7.7e-08 32.1 0.0 2.3e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX81951.1 - 0.011 15.1 0.0 0.56 9.5 0.0 2.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Yae1_N PF09811.9 KXX81952.1 - 1.5e-10 40.6 5.9 2.6e-10 39.8 5.9 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Trns_repr_metal PF02583.17 KXX81952.1 - 0.16 12.4 2.7 0.21 12.0 1.3 1.8 1 1 1 2 2 2 0 Metal-sensitive transcriptional repressor Anp1 PF03452.14 KXX81953.1 - 4.2e-109 364.0 0.0 5e-109 363.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.25 KXX81954.1 - 3.8e-14 53.0 0.0 7.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Acyl-thio_N PF12590.8 KXX81954.1 - 0.067 13.8 1.3 6.4 7.3 0.8 2.4 2 0 0 2 2 2 0 Acyl-ATP thioesterase Mito_carr PF00153.27 KXX81955.1 - 2.7e-62 206.7 1.4 1.1e-22 79.7 0.1 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.16 KXX81956.1 - 5.1e-44 148.3 0.3 5.9e-44 148.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DnaJ_C PF01556.18 KXX81957.1 - 1.1e-29 103.4 0.0 1.6e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXX81957.1 - 1.1e-26 92.8 4.0 1.7e-26 92.1 4.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXX81957.1 - 3.2e-13 49.8 17.9 5.1e-13 49.2 17.9 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KXX81957.1 - 0.016 15.3 8.0 0.31 11.1 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KXX81957.1 - 2.5 8.1 9.0 7.5 6.6 1.8 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein RNA_Me_trans PF04252.13 KXX81958.1 - 6.1e-83 277.3 0.0 6.9e-83 277.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 KXX81959.1 - 4.2e-114 382.2 0.0 6.2e-114 381.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase GRA6 PF05084.13 KXX81959.1 - 0.046 13.7 1.1 0.077 13.0 0.8 1.6 1 1 0 1 1 1 0 Granule antigen protein (GRA6) DHquinase_I PF01487.15 KXX81960.1 - 3.1e-46 158.5 0.0 4.4e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase GidB PF02527.15 KXX81960.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF2228 PF10228.9 KXX81960.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DHO_dh PF01180.21 KXX81961.1 - 7.6e-18 64.7 0.0 1.3e-17 63.9 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 KXX81961.1 - 0.093 11.7 0.3 0.13 11.2 0.3 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain LRR_6 PF13516.6 KXX81962.1 - 0.00011 22.0 18.0 13 6.1 0.1 8.8 9 0 0 9 9 9 4 Leucine Rich repeat Ribosomal_L5e PF17144.4 KXX81963.1 - 1.4e-79 265.8 0.1 2.1e-79 265.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KXX81963.1 - 4.9e-35 120.4 8.3 4.9e-35 120.4 8.3 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KXX81963.1 - 0.039 14.3 0.1 0.09 13.2 0.1 1.6 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast HAD_2 PF13419.6 KXX81964.1 - 0.00023 21.3 0.0 0.00049 20.2 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX81964.1 - 0.047 14.0 0.0 0.14 12.4 0.0 1.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-UBR PF02207.20 KXX81965.1 - 5.9e-14 52.0 4.9 5.9e-14 52.0 4.9 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ATG2_CAD PF13329.6 KXX81966.1 - 4.8e-51 172.6 0.0 1.4e-50 171.0 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KXX81966.1 - 1.2e-31 108.9 3.6 5.8e-31 106.7 0.4 3.4 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 KXX81966.1 - 6.1e-07 29.6 0.1 3.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KXX81966.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Amino_oxidase PF01593.24 KXX81967.1 - 9e-55 186.7 0.0 1.2e-54 186.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX81967.1 - 2.9e-16 59.4 0.0 6.3e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXX81967.1 - 3e-09 37.0 0.1 3.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXX81967.1 - 7.6e-09 35.2 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX81967.1 - 2.1e-05 24.3 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX81967.1 - 3.8e-05 22.6 0.1 0.0018 17.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXX81967.1 - 0.00015 22.2 0.1 0.00038 21.0 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX81967.1 - 0.0011 18.1 0.1 0.0028 16.8 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXX81967.1 - 0.0018 17.6 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXX81967.1 - 0.0048 16.2 0.1 0.0073 15.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXX81967.1 - 0.013 14.9 0.1 0.023 14.1 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXX81967.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KXX81967.1 - 0.038 13.2 0.5 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXX81967.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXX81967.1 - 0.19 10.7 0.2 1 8.3 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Prenylcys_lyase PF07156.14 KXX81967.1 - 0.22 10.6 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase GIDA PF01134.22 KXX81967.1 - 0.24 10.4 0.1 0.65 9.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Acyl-CoA_dh_1 PF00441.24 KXX81968.1 - 8e-35 120.3 1.0 1.2e-34 119.7 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXX81968.1 - 3.8e-20 71.8 0.1 1e-19 70.5 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXX81968.1 - 1.7e-15 57.0 0.1 3.1e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXX81968.1 - 1.5e-05 25.6 0.1 9.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXX81968.1 - 5.6e-05 23.4 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC PF00098.23 KXX81969.1 - 1.8e-48 160.5 56.7 7.7e-09 35.2 4.3 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KXX81969.1 - 4e-10 39.3 33.5 0.011 15.4 0.9 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 KXX81969.1 - 1.1e-09 38.1 35.5 0.076 13.0 1.1 6.2 3 2 3 6 6 6 6 Zinc knuckle zf-CCHC_6 PF15288.6 KXX81969.1 - 0.004 17.0 44.8 0.044 13.6 1.9 6.4 5 2 2 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.6 KXX81969.1 - 0.022 14.6 1.4 0.022 14.6 1.4 6.9 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_5 PF14787.6 KXX81969.1 - 0.064 13.0 40.0 2.1 8.1 0.7 7.0 5 2 2 7 7 7 0 GAG-polyprotein viral zinc-finger DUF2353 PF09789.9 KXX81970.1 - 0.0007 19.1 1.2 0.001 18.5 1.2 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) WXG100 PF06013.12 KXX81970.1 - 0.0033 17.6 3.0 0.018 15.2 1.3 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG JAKMIP_CC3 PF16034.5 KXX81970.1 - 0.01 15.8 4.2 0.16 11.9 0.5 2.3 2 0 0 2 2 2 0 JAKMIP CC3 domain GAS PF13851.6 KXX81970.1 - 0.011 15.1 3.3 0.083 12.2 0.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_I PF06008.14 KXX81970.1 - 0.019 14.7 1.7 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain I Dynamitin PF04912.14 KXX81970.1 - 0.043 13.1 3.0 0.11 11.8 0.4 2.1 1 1 1 2 2 2 0 Dynamitin Fmp27_WPPW PF10359.9 KXX81970.1 - 0.046 12.6 1.6 0.12 11.2 0.1 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Uso1_p115_C PF04871.13 KXX81970.1 - 0.047 14.1 9.5 1.2 9.5 0.5 2.7 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 KXX81970.1 - 0.051 13.6 1.2 9.9 6.2 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 KXX81970.1 - 0.057 13.7 9.1 0.43 10.8 0.3 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper ATG16 PF08614.11 KXX81970.1 - 0.083 13.1 10.5 0.18 12.0 10.5 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 KXX81970.1 - 0.089 13.2 4.2 13 6.3 0.1 2.9 2 1 1 3 3 3 0 Cell division protein ZapB KASH_CCD PF14662.6 KXX81970.1 - 0.25 11.2 3.5 0.39 10.5 1.8 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 KXX81970.1 - 0.25 12.0 0.6 2.1 9.0 0.1 2.3 2 1 0 2 2 2 0 Initiation control protein YabA Rootletin PF15035.6 KXX81970.1 - 0.49 10.4 6.9 1.3 9.0 0.6 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Ax_dynein_light PF10211.9 KXX81970.1 - 1.1 9.2 5.3 5.9 6.8 0.2 2.8 2 1 1 3 3 3 0 Axonemal dynein light chain TMF_TATA_bd PF12325.8 KXX81970.1 - 1.9 8.8 5.8 10 6.4 1.3 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 KXX81970.1 - 4.5 7.3 9.2 3.1 7.8 1.4 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 KXX81970.1 - 5.2 7.2 12.2 1.7 8.8 1.6 3.1 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Trp_syntA PF00290.20 KXX81971.1 - 4e-98 327.4 0.0 1.5e-97 325.6 0.0 1.8 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 KXX81971.1 - 3.3e-47 161.3 0.9 5.6e-47 160.6 0.9 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.17 KXX81971.1 - 0.19 11.1 0.2 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 PcrB family Baculo_PEP_C PF04513.12 KXX81972.1 - 0.21 11.6 14.3 0.27 11.3 0.4 4.2 3 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 KXX81972.1 - 0.27 10.6 0.4 26 4.1 0.1 2.8 3 0 0 3 3 3 0 SF-assemblin/beta giardin GFA PF04828.14 KXX81973.1 - 1.8e-11 44.2 0.2 2.7e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DEAD PF00270.29 KXX81974.1 - 7.1e-47 159.4 0.0 2.6e-46 157.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX81974.1 - 1e-24 87.0 0.0 1.3e-23 83.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXX81974.1 - 3.4e-19 68.8 0.2 8.5e-19 67.6 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXX81974.1 - 0.00046 20.2 1.5 0.00051 20.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MFMR_assoc PF16596.5 KXX81974.1 - 1.6 9.2 11.3 3.1 8.3 11.3 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR 6PF2K PF01591.18 KXX81975.1 - 1.5e-77 259.9 0.0 2e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXX81975.1 - 2.6e-34 118.6 0.0 4.1e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXX81975.1 - 8.1e-05 22.8 0.0 0.00018 21.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXX81975.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MRP-S28 PF10213.9 KXX81976.1 - 6.5e-50 168.8 0.4 1.8e-49 167.4 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Aldedh PF00171.22 KXX81977.1 - 1.8e-83 280.6 0.0 2.2e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ECR1_N PF14382.6 KXX81978.1 - 8.1e-16 57.5 0.2 1.8e-15 56.4 0.2 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KXX81978.1 - 5e-06 26.8 0.7 9.6e-06 25.9 0.7 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KXX81978.1 - 0.14 12.8 0.5 1.3 9.7 0.1 2.6 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 HET PF06985.11 KXX81980.1 - 6.1e-22 78.6 0.0 9.4e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KXX81981.1 - 9.6e-29 99.0 31.2 0.00028 21.6 0.6 11.0 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX81981.1 - 2.1e-14 53.6 5.6 0.013 15.8 0.0 7.6 4 3 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXX81981.1 - 0.001 19.0 0.7 0.9 9.6 0.0 4.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXX81981.1 - 0.0028 16.7 5.9 0.98 8.3 0.3 4.8 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_tran_28_C PF04101.16 KXX81982.1 - 2e-18 66.9 1.3 3.6e-17 62.9 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain PKI PF02827.16 KXX81982.1 - 0.11 12.7 2.0 0.23 11.7 2.0 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF3043 PF11241.8 KXX81982.1 - 2 8.4 3.8 3.1 7.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4834 PF16118.5 KXX81982.1 - 3.4 8.7 5.7 6.7 7.7 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 KXX81982.1 - 4.9 6.7 18.6 7.8 6.0 18.6 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 KXX81982.1 - 5.1 7.0 14.7 7.9 6.4 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 KXX81982.1 - 5.3 5.9 16.2 8.2 5.2 16.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) HET PF06985.11 KXX81983.1 - 4e-11 43.5 8.2 1.3e-09 38.6 1.9 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pribosyltran PF00156.27 KXX81985.1 - 0.0055 16.2 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Abhydrolase_3 PF07859.13 KXX81986.1 - 1.5e-20 74.0 0.1 1.9e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXX81986.1 - 2.1e-18 66.4 0.0 4.2e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase NYAP_N PF15439.6 KXX81987.1 - 0.0045 16.3 3.3 0.0074 15.5 3.3 1.3 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 4PPT_N PF17837.1 KXX81987.1 - 0.021 15.0 0.3 0.057 13.6 0.3 1.7 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain HAUS4 PF14735.6 KXX81987.1 - 0.03 14.0 2.1 0.21 11.3 2.1 2.2 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 4 XPC-binding PF09280.11 KXX81987.1 - 0.078 12.7 4.2 2.1 8.1 0.1 3.1 3 0 0 3 3 3 0 XPC-binding domain DinB_2 PF12867.7 KXX81987.1 - 3.2 8.3 8.3 13 6.3 7.0 2.6 2 1 0 2 2 2 0 DinB superfamily Ribosomal_L28 PF00830.19 KXX81988.1 - 1.6e-20 73.1 0.8 2.5e-20 72.4 0.8 1.3 1 0 0 1 1 1 1 Ribosomal L28 family NAD_binding_10 PF13460.6 KXX81989.1 - 7.5e-10 39.0 0.1 1e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX81989.1 - 5.5e-09 35.9 0.2 7.8e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXX81989.1 - 0.0002 20.9 0.0 0.00035 20.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX81989.1 - 0.00046 19.8 0.2 0.00098 18.7 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXX81989.1 - 0.00047 19.7 0.0 0.0011 18.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SelB-wing_1 PF09105.10 KXX81989.1 - 0.0087 16.0 0.1 0.027 14.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor SelB, winged helix Peripla_BP_4 PF13407.6 KXX81989.1 - 0.014 15.0 1.3 0.068 12.7 0.2 2.3 2 1 1 3 3 3 0 Periplasmic binding protein domain FAD_binding_2 PF00890.24 KXX81989.1 - 0.037 13.1 2.4 0.069 12.2 2.4 1.8 1 1 0 1 1 1 0 FAD binding domain HEM4 PF02602.15 KXX81989.1 - 0.061 12.7 0.3 1.5 8.1 0.2 2.3 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Phytase-like PF13449.6 KXX81990.1 - 1.5e-38 133.4 0.1 2.8e-38 132.5 0.1 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase PLDc PF00614.22 KXX81991.1 - 7.8e-17 60.7 0.4 5.2e-08 32.8 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KXX81991.1 - 2.5e-13 50.0 0.0 4.3e-07 29.9 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KXX81991.1 - 6.5e-07 29.3 0.4 5.9e-06 26.2 0.0 2.7 2 1 0 2 2 2 1 PX domain COQ7 PF03232.13 KXX81992.1 - 1.6e-70 236.4 0.2 2e-70 236.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KXX81992.1 - 0.00019 21.8 0.0 0.00037 20.9 0.0 1.5 2 0 0 2 2 2 1 Rubrerythrin Crr6 PF08847.11 KXX81992.1 - 0.043 13.5 0.1 2.1 8.0 0.0 2.3 1 1 1 2 2 2 0 Chlororespiratory reduction 6 Vitellogenin_N PF01347.22 KXX81992.1 - 0.14 10.5 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Oxidored_q6 PF01058.22 KXX81993.1 - 3.2e-22 78.8 0.0 4.4e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tubulin PF00091.25 KXX81994.1 - 2.5e-67 226.9 0.0 3.5e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXX81994.1 - 2.4e-45 153.7 0.3 6.8e-45 152.3 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXX81994.1 - 1.7e-07 31.6 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXX81994.1 - 0.058 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain SPX PF03105.19 KXX81995.1 - 1.4e-10 41.7 13.2 0.00014 21.9 0.1 4.1 2 1 2 4 4 4 3 SPX domain CcmD PF04995.14 KXX81995.1 - 0.074 13.1 0.2 0.074 13.1 0.2 3.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Mpp10 PF04006.12 KXX81996.1 - 1.6e-102 343.9 62.3 1.4e-101 340.9 62.3 1.9 1 1 0 1 1 1 1 Mpp10 protein Mur_ligase_M PF08245.12 KXX81996.1 - 0.21 11.5 0.1 0.56 10.2 0.0 1.6 2 0 0 2 2 2 0 Mur ligase middle domain Amidohydro_3 PF07969.11 KXX81997.1 - 1.9e-65 222.2 0.2 2.4e-65 221.8 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXX81997.1 - 4.8e-05 22.8 0.3 0.00041 19.8 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family RskA PF10099.9 KXX81997.1 - 0.29 11.4 3.1 0.62 10.3 0.2 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA NMO PF03060.15 KXX81998.1 - 1.3e-36 126.7 10.6 1.1e-30 107.1 6.7 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KXX81998.1 - 5.1e-07 29.0 12.7 9.9e-07 28.1 12.4 1.5 1 1 1 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXX81998.1 - 7.2e-07 28.5 12.2 6.8e-06 25.3 12.2 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXX81998.1 - 0.0036 16.5 5.9 0.0059 15.8 5.9 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KXX81998.1 - 0.3 10.3 3.6 0.67 9.2 2.8 2.0 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG RRM_1 PF00076.22 KXX81999.1 - 1.7e-16 59.7 0.0 2.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4472 PF14739.6 KXX81999.1 - 0.047 14.4 3.6 0.065 14.0 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Nup35_RRM_2 PF14605.6 KXX81999.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ADIP PF11559.8 KXX81999.1 - 0.064 13.3 3.2 0.087 12.9 3.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 KXX81999.1 - 0.15 9.9 2.0 0.19 9.6 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 KXX81999.1 - 0.16 11.8 6.2 0.23 11.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 KXX81999.1 - 0.42 9.9 5.6 0.58 9.4 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.15 KXX81999.1 - 0.53 10.1 4.5 0.83 9.5 4.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.11 KXX81999.1 - 0.62 8.9 6.7 0.85 8.4 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GRP PF07172.11 KXX81999.1 - 8.4 7.2 18.7 0.2 12.4 11.8 1.8 2 1 0 2 2 2 0 Glycine rich protein family HECT PF00632.25 KXX82000.1 - 7.5e-95 317.9 0.0 1.1e-94 317.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KXX82000.1 - 3.7e-34 116.5 23.5 2e-12 47.0 5.3 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KXX82000.1 - 6.5e-20 71.4 0.0 2.2e-19 69.6 0.0 2.0 1 0 0 1 1 1 1 C2 domain DUF829 PF05705.14 KXX82001.1 - 6.4e-41 140.8 0.0 7.9e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) F-box PF00646.33 KXX82003.1 - 2.5e-07 30.4 0.1 7.6e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX82003.1 - 6.3e-05 22.8 0.2 0.00018 21.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KXX82004.1 - 1.8e-28 99.5 31.8 1.8e-28 99.5 31.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 KXX82005.1 - 1.4e-93 314.0 0.0 1.6e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M13_N PF05649.13 KXX82006.1 - 6.4e-96 322.3 0.0 8.6e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KXX82006.1 - 3.1e-61 206.6 0.2 7.3e-61 205.4 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M13 CBM_20 PF00686.19 KXX82008.1 - 4e-33 113.2 0.1 7.3e-33 112.4 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 KXX82008.1 - 3.4e-10 40.9 1.1 8e-10 39.7 1.1 1.7 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Cellulase PF00150.18 KXX82009.1 - 7.7e-17 61.6 8.4 1.5e-16 60.7 8.4 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXX82009.1 - 4e-07 29.5 0.0 2.7e-06 26.7 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KXX82009.1 - 0.00024 20.6 0.7 0.001 18.5 0.1 2.3 2 1 0 2 2 2 1 Beta-galactosidase FAD_binding_4 PF01565.23 KXX82011.1 - 5.1e-20 71.6 1.6 1e-19 70.6 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 KXX82011.1 - 6.5e-12 45.0 33.1 2.6e-07 29.9 27.9 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily BBE PF08031.12 KXX82011.1 - 1.5e-07 31.4 0.2 3.4e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3664 PF12406.8 KXX82011.1 - 0.21 12.2 0.9 0.41 11.3 0.9 1.4 1 0 0 1 1 1 0 Surface protein CorA PF01544.18 KXX82012.1 - 0.091 12.1 0.2 0.88 8.8 0.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein F-box-like PF12937.7 KXX82014.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 F-box-like Tctex-1 PF03645.13 KXX82015.1 - 5.9e-37 126.0 0.0 7e-37 125.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family KH_1 PF00013.29 KXX82016.1 - 6.5e-48 160.4 12.1 2e-16 59.5 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXX82016.1 - 5.1e-11 42.2 3.8 0.022 14.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXX82016.1 - 2.7e-10 40.0 4.6 0.023 14.6 0.0 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KXX82016.1 - 1.5e-05 24.9 0.0 0.24 11.4 0.0 3.2 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 KXX82016.1 - 0.0059 16.7 3.5 4.2 7.5 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain CTP_transf_like PF01467.26 KXX82017.1 - 4.2e-31 108.1 0.0 7.5e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF4611 PF15387.6 KXX82017.1 - 1.9 8.8 7.3 3.5 7.9 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nop14 PF04147.12 KXX82018.1 - 0.58 8.3 2.5 0.8 7.8 2.5 1.1 1 0 0 1 1 1 0 Nop14-like family Plus-3 PF03126.18 KXX82019.1 - 5.7e-19 68.6 0.1 1.7e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 Plus-3 domain DUF202 PF02656.15 KXX82020.1 - 7.9e-16 58.3 5.4 1.2e-15 57.7 3.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.20 KXX82020.1 - 0.029 14.2 6.9 0.037 13.9 6.9 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF983 PF06170.12 KXX82020.1 - 0.16 12.4 3.6 8.4 6.9 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF983) Alba PF01918.21 KXX82021.1 - 3.1e-09 36.5 0.0 5.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Alba zf-H2C2_2 PF13465.6 KXX82022.1 - 3.1e-13 49.5 8.0 2e-07 31.2 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KXX82022.1 - 9.6e-13 47.8 11.9 4.2e-06 26.9 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX82022.1 - 1.3e-08 34.9 10.6 0.00052 20.6 1.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXX82022.1 - 3.4e-08 33.3 5.7 0.00027 20.8 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX82022.1 - 9.2e-06 25.8 0.5 0.2 12.0 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX82022.1 - 3.6e-05 24.0 1.0 0.011 16.1 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXX82022.1 - 0.028 14.2 5.4 1.5 8.7 1.0 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 KXX82022.1 - 0.056 14.0 0.9 0.13 12.8 0.9 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 KXX82022.1 - 0.086 13.1 1.4 0.16 12.2 1.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 KXX82022.1 - 0.17 12.1 2.9 9.4 6.6 0.1 2.4 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 KXX82022.1 - 6.2 7.1 6.7 21 5.3 1.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain Aminotran_1_2 PF00155.21 KXX82023.1 - 1.4e-62 212.0 0.0 3.4e-42 144.9 0.0 2.3 2 1 1 3 3 3 2 Aminotransferase class I and II Nop52 PF05997.12 KXX82024.1 - 1.3e-52 178.8 0.0 2.5e-52 177.8 0.0 1.4 1 1 0 1 1 1 1 Nucleolar protein,Nop52 Syntaxin-18_N PF10496.9 KXX82025.1 - 2.5e-07 30.8 0.3 4e-06 27.0 0.0 2.7 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Chlor_dismutase PF06778.12 KXX82025.1 - 0.074 12.6 0.2 0.28 10.7 0.1 1.9 2 0 0 2 2 2 0 Chlorite dismutase DUF16 PF01519.16 KXX82025.1 - 0.09 13.3 0.7 0.59 10.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3071 PF11268.8 KXX82025.1 - 0.27 11.3 4.6 0.35 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) MFS_1 PF07690.16 KXX82026.1 - 3.7e-47 161.0 20.4 3.7e-47 161.0 20.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX82026.1 - 2.5e-09 36.5 9.8 2.5e-09 36.5 9.8 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXX82026.1 - 0.0052 15.7 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 MFS_1 like family OATP PF03137.20 KXX82026.1 - 0.51 8.6 5.9 0.22 9.7 0.9 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family YlaC PF10777.9 KXX82026.1 - 0.62 9.9 2.2 1.9 8.3 0.6 2.3 2 0 0 2 2 2 0 Inner membrane protein YlaC DUF1422 PF07226.11 KXX82026.1 - 2.5 8.2 6.7 1.1 9.3 0.1 3.3 3 2 0 4 4 4 0 Protein of unknown function (DUF1422) APH PF01636.23 KXX82029.1 - 0.00082 19.4 0.2 0.00082 19.4 0.2 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KXX82029.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Presenilin PF01080.17 KXX82029.1 - 0.046 12.5 9.3 0.07 11.9 9.3 1.3 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.11 KXX82029.1 - 0.38 10.1 28.8 0.68 9.3 28.8 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF913 PF06025.12 KXX82029.1 - 0.79 8.6 5.3 1.4 7.8 5.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF-3_zeta PF05091.12 KXX82029.1 - 1.6 7.6 11.1 2.4 7.0 11.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5401 PF17380.2 KXX82029.1 - 5.5 4.9 37.6 8.2 4.4 37.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF3659 PF12396.8 KXX82030.1 - 3.6e-16 58.8 2.3 4.2e-11 42.6 0.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) ORC6 PF05460.13 KXX82030.1 - 0.57 9.4 6.8 0.77 9.0 6.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4551 PF15087.6 KXX82030.1 - 3.9 6.2 4.8 4.6 6.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ctr PF04145.15 KXX82032.1 - 7.1e-29 101.3 10.2 1.1e-27 97.5 10.2 2.0 1 1 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.21 KXX82032.1 - 0.061 13.1 1.3 0.29 10.9 0.1 2.0 2 0 0 2 2 2 0 PAP2 superfamily DUF4574 PF15141.6 KXX82032.1 - 0.12 12.3 0.8 3.1 7.8 0.3 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 NUDIX PF00293.28 KXX82033.1 - 1.9e-08 34.4 0.0 7.7e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain DUF5404 PF17397.2 KXX82033.1 - 2.6 8.2 5.7 41 4.3 3.4 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5404) FAA_hydrolase PF01557.18 KXX82034.1 - 4.7e-50 170.3 0.0 5.7e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 KXX82035.1 - 8.7e-57 191.0 0.1 6.8e-46 155.6 0.0 2.0 1 1 1 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KXX82035.1 - 3e-05 23.6 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXX82035.1 - 0.0026 17.7 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXX82035.1 - 0.0027 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Cupin DZR PF12773.7 KXX82035.1 - 0.046 13.8 0.4 0.12 12.4 0.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon ARD PF03079.14 KXX82035.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family EXS PF03124.14 KXX82037.1 - 1.5e-107 359.8 8.6 1.7e-107 359.6 8.6 1.0 1 0 0 1 1 1 1 EXS family ADH_zinc_N PF00107.26 KXX82038.1 - 4.3e-07 30.0 0.1 2.2e-06 27.7 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX82038.1 - 4.9e-05 23.2 1.1 0.001 18.9 0.4 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXX82038.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase NARP1 PF12569.8 KXX82039.1 - 2.5e-203 676.7 14.0 3.9e-200 666.1 7.8 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 KXX82039.1 - 4.5e-21 75.2 31.4 2.1e-05 25.1 8.2 8.4 9 1 1 10 10 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXX82039.1 - 5e-19 68.6 22.5 0.00015 22.2 0.1 7.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXX82039.1 - 6.3e-15 54.6 29.4 0.00098 19.8 0.0 10.3 8 3 3 11 11 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXX82039.1 - 1.2e-13 50.4 9.8 0.001 19.3 0.0 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXX82039.1 - 4.3e-12 45.2 45.9 0.00061 19.7 0.1 11.1 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXX82039.1 - 4.3e-11 42.8 15.1 0.00061 19.9 0.0 7.4 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXX82039.1 - 1.5e-10 40.6 14.6 0.0012 18.5 0.1 6.2 6 0 0 6 6 6 4 TPR repeat ANAPC3 PF12895.7 KXX82039.1 - 8.1e-09 35.6 15.4 0.0034 17.6 1.5 5.0 4 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXX82039.1 - 1.1e-08 34.6 26.3 0.0032 17.6 0.0 9.0 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXX82039.1 - 1.3e-08 34.3 35.5 2.1e-05 24.1 0.1 9.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXX82039.1 - 2.5e-08 34.1 20.3 0.018 15.3 0.0 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXX82039.1 - 1.6e-05 24.9 4.0 2.7 8.1 0.1 5.3 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 KXX82039.1 - 0.00086 19.2 0.9 1.1 9.3 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat YcaO_C PF18381.1 KXX82039.1 - 0.0015 18.4 1.2 0.0066 16.4 0.1 2.4 2 1 1 3 3 3 1 YcaO cyclodehydratase C-terminal domain TPR_10 PF13374.6 KXX82039.1 - 0.007 16.2 20.2 0.2 11.6 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat PPTA PF01239.22 KXX82039.1 - 0.012 15.3 1.1 2.6 7.9 0.0 3.6 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat BTAD PF03704.17 KXX82039.1 - 0.016 15.6 2.8 0.016 15.6 2.8 3.2 4 1 0 4 4 2 0 Bacterial transcriptional activator domain TPR_7 PF13176.6 KXX82039.1 - 0.021 14.8 15.9 21 5.4 0.0 7.6 7 1 1 8 8 7 0 Tetratricopeptide repeat DUF4919 PF16266.5 KXX82039.1 - 0.48 10.4 4.8 0.44 10.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) DAGK_cat PF00781.24 KXX82040.1 - 4.5e-23 81.2 0.0 6.9e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3323 PF11796.8 KXX82042.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Chalcone_3 PF16036.5 KXX82043.1 - 0.028 14.5 0.1 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 Chalcone isomerase-like UPF0560 PF10577.9 KXX82044.1 - 0.029 12.9 0.0 0.032 12.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Vpu PF00558.19 KXX82044.1 - 0.084 12.7 0.4 0.1 12.4 0.4 1.1 1 0 0 1 1 1 0 Vpu protein Orf78 PF06024.12 KXX82044.1 - 0.086 13.1 0.0 0.094 13.0 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Ribosomal_S5_C PF03719.15 KXX82045.1 - 3.7e-23 80.8 0.0 2.5e-22 78.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXX82045.1 - 1.3e-16 60.3 0.0 2.2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.10 KXX82046.1 - 5.9e-26 90.3 0.6 1.1e-24 86.3 0.6 2.0 1 1 0 1 1 1 1 DASH complex subunit Dad3 DAG1 PF05454.11 KXX82046.1 - 0.046 13.1 0.4 0.049 13.0 0.4 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PARP PF00644.20 KXX82047.1 - 4.6e-11 42.7 0.1 8.4e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KXX82047.1 - 9.4e-08 31.8 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COG5 PF10392.9 KXX82048.1 - 6.9e-05 23.0 2.2 0.0021 18.2 0.1 3.0 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Cdh1_DBD_1 PF18196.1 KXX82048.1 - 0.038 14.3 1.0 0.08 13.3 1.0 1.5 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF5082 PF16888.5 KXX82048.1 - 0.069 13.4 1.0 20 5.4 0.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF3486 PF11985.8 KXX82048.1 - 0.099 13.1 0.5 0.099 13.1 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3486) Phage_pRha PF09669.10 KXX82048.1 - 0.18 12.4 0.0 0.42 11.2 0.0 1.6 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Ribosomal_60s PF00428.19 KXX82048.1 - 0.39 11.3 4.3 2.1 9.0 4.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein ATE_C PF04377.15 KXX82049.1 - 1.4e-48 164.9 0.0 2.4e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KXX82049.1 - 2.9e-20 72.5 0.3 6.4e-20 71.3 0.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KXX82049.1 - 0.14 12.3 2.3 0.18 12.0 0.2 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain NUDIX PF00293.28 KXX82050.1 - 5.5e-17 62.0 1.1 6.9e-17 61.7 1.1 1.1 1 0 0 1 1 1 1 NUDIX domain 2-Hacid_dh_C PF02826.19 KXX82051.1 - 7.1e-57 191.6 0.0 9.6e-57 191.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXX82051.1 - 2.6e-20 72.5 0.0 4e-20 71.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXX82051.1 - 4.2e-05 23.8 0.0 7.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.18 KXX82052.1 - 1.1e-07 31.9 11.0 1.6e-07 31.3 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KXX82052.1 - 0.023 14.8 1.6 0.023 14.8 1.6 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 JAB PF01398.21 KXX82053.1 - 3.2e-09 36.8 0.3 5.8e-08 32.7 0.3 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1574 PF07611.11 KXX82053.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) AdoHcyase PF05221.17 KXX82054.1 - 7.5e-133 442.3 0.0 2.1e-74 250.3 0.3 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KXX82054.1 - 3.8e-82 274.1 2.6 6.8e-82 273.3 2.6 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXX82054.1 - 1.9e-06 27.3 0.2 5.1e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KXX82054.1 - 0.028 14.0 0.2 0.053 13.1 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KXX82054.1 - 0.075 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.21 KXX82054.1 - 0.094 12.4 0.5 0.27 10.9 0.4 1.9 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase zf-LYAR PF08790.11 KXX82056.1 - 3.5e-14 52.4 1.7 3.5e-14 52.4 1.7 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Pex2_Pex12 PF04757.14 KXX82057.1 - 4e-46 157.4 3.3 5.2e-46 157.1 3.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KXX82057.1 - 9.3e-12 44.6 7.9 1.5e-11 43.9 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX82057.1 - 4.4e-11 42.9 8.6 7.4e-11 42.2 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXX82057.1 - 3.5e-10 39.6 5.7 5.4e-10 39.0 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX82057.1 - 8.5e-10 38.4 6.1 1.4e-09 37.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX82057.1 - 6.5e-08 32.5 6.7 1.3e-07 31.5 6.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXX82057.1 - 9.4e-08 31.8 6.8 1.5e-07 31.1 6.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXX82057.1 - 1.5e-07 31.3 5.0 2.6e-07 30.5 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXX82057.1 - 6.9e-07 29.3 7.7 1.2e-06 28.6 7.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXX82057.1 - 7.8e-07 29.3 6.9 1.5e-06 28.4 6.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KXX82057.1 - 0.00051 19.9 2.4 0.001 18.9 2.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KXX82057.1 - 0.00076 19.6 6.1 0.0014 18.7 6.1 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 KXX82057.1 - 0.0087 15.9 1.0 0.015 15.1 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXX82057.1 - 0.066 13.0 5.8 0.15 11.8 5.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXX82057.1 - 0.16 12.0 2.4 0.31 11.1 2.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXX82057.1 - 0.22 11.3 3.4 0.51 10.1 3.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KXX82057.1 - 0.61 9.7 5.5 1.1 8.9 5.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ABC_tran PF00005.27 KXX82058.1 - 6.4e-48 162.7 0.0 7.3e-26 91.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXX82058.1 - 2.3e-17 63.7 0.7 3.3e-07 30.4 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system R3H PF01424.22 KXX82058.1 - 2.3e-15 56.3 1.7 5.1e-15 55.2 0.2 2.2 2 0 0 2 2 2 1 R3H domain ABC2_membrane_3 PF12698.7 KXX82058.1 - 1e-11 44.6 45.8 5.4e-07 29.0 24.9 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 KXX82058.1 - 4.7e-09 36.0 0.0 0.02 14.3 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXX82058.1 - 2.4e-06 28.2 0.1 0.013 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain zf-NF-X1 PF01422.17 KXX82058.1 - 3.8e-06 26.8 14.3 3.8e-06 26.8 14.3 9.7 10 0 0 10 10 8 5 NF-X1 type zinc finger RsgA_GTPase PF03193.16 KXX82058.1 - 1.2e-05 25.3 0.2 0.046 13.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXX82058.1 - 1.9e-05 25.1 5.3 0.069 13.5 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 KXX82058.1 - 3.3e-05 23.6 0.2 0.38 10.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KXX82058.1 - 8.4e-05 22.4 0.1 0.24 11.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KXX82058.1 - 0.0035 17.1 0.0 1.5 8.4 0.2 2.7 3 0 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 KXX82058.1 - 0.0081 16.1 0.1 2.6 7.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 KXX82058.1 - 0.017 14.8 0.3 2.9 7.5 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KXX82058.1 - 0.02 15.2 0.1 6.9 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF4162 PF13732.6 KXX82058.1 - 0.041 14.6 0.0 0.26 12.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_27 PF13514.6 KXX82058.1 - 0.061 12.9 0.2 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXX82058.1 - 0.079 12.2 0.2 15 4.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 KXX82058.1 - 0.18 12.2 0.4 5.8 7.4 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KXX82058.1 - 0.32 10.6 0.5 31 4.2 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase SbcCD_C PF13558.6 KXX82058.1 - 0.48 10.7 5.4 6.8 7.0 0.0 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Hydrolase_4 PF12146.8 KXX82059.1 - 4.1e-19 68.8 0.0 2e-13 50.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX82059.1 - 7.5e-12 45.4 0.2 1.6e-08 34.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX82059.1 - 1.7e-06 28.8 0.2 6.5e-06 26.9 0.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KXX82059.1 - 4.7e-05 23.2 0.0 0.00019 21.2 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 KXX82059.1 - 5.4e-05 22.0 0.1 1.7 7.2 0.1 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 KXX82059.1 - 0.0002 20.4 0.0 0.00028 19.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 KXX82059.1 - 0.005 16.3 0.0 0.056 12.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXX82059.1 - 0.0088 15.6 0.0 5.4 6.5 0.0 2.7 2 1 1 3 3 3 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KXX82059.1 - 0.03 13.9 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KXX82059.1 - 0.03 14.2 0.0 0.4 10.6 0.0 2.4 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KXX82059.1 - 0.085 12.6 0.0 3.6 7.3 0.0 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KXX82059.1 - 0.1 12.4 0.2 0.35 10.7 0.1 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KXX82059.1 - 0.19 11.4 0.3 2.1 8.0 0.3 2.1 1 1 0 1 1 1 0 PGAP1-like protein p450 PF00067.22 KXX82060.1 - 7.1e-57 193.2 0.0 8.3e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3450 PF11932.8 KXX82060.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CFEM PF05730.11 KXX82061.1 - 8.5e-14 51.4 11.1 1.9e-13 50.3 11.1 1.6 1 0 0 1 1 1 1 CFEM domain Herpes_US9 PF06072.11 KXX82061.1 - 1.3 9.0 6.9 0.24 11.3 2.1 2.3 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Zn_clus PF00172.18 KXX82062.1 - 4.5e-08 33.1 11.7 1.3e-07 31.6 11.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX82062.1 - 6.7e-06 25.1 0.4 1e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.17 KXX82063.1 - 2.4e-51 174.9 0.1 3.1e-51 174.6 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.16 KXX82064.1 - 6.7e-46 156.8 51.3 3.6e-45 154.4 49.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX82064.1 - 1.6e-20 73.1 25.2 1e-19 70.5 25.2 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX82064.1 - 2.1e-09 36.8 11.4 2.1e-09 36.8 11.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXX82064.1 - 0.0031 15.9 0.6 0.0031 15.9 0.6 2.3 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Caveolin PF01146.17 KXX82064.1 - 2.5 8.1 5.0 2.4 8.1 3.1 2.0 2 0 0 2 2 2 0 Caveolin MnhB PF04039.13 KXX82065.1 - 8.8 6.7 12.4 0.13 12.5 2.3 2.5 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF3659 PF12396.8 KXX82066.1 - 3.5e-103 337.5 51.9 3.3e-22 78.2 2.2 5.5 5 0 0 5 5 5 5 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 KXX82066.1 - 0.0078 16.1 0.8 23 5.0 0.0 4.4 4 0 0 4 4 4 2 Glycine cleavage T-protein C-terminal barrel domain Trypan_PARP PF05887.11 KXX82066.1 - 0.0082 16.1 0.3 0.0082 16.1 0.3 6.2 5 1 3 8 8 8 1 Procyclic acidic repetitive protein (PARP) SNF2_N PF00176.23 KXX82067.1 - 1.4e-71 241.1 0.0 2.2e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXX82067.1 - 7.2e-19 67.5 0.0 1.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXX82067.1 - 7e-15 55.3 0.0 2e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXX82067.1 - 7.6e-08 32.1 14.0 7.6e-08 32.1 14.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX82067.1 - 8.9e-08 31.9 15.5 9.2e-08 31.8 11.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX82067.1 - 1.9e-07 30.9 11.5 4.4e-07 29.8 11.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXX82067.1 - 2.2e-07 31.1 13.5 2.2e-07 31.1 13.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXX82067.1 - 5.3e-07 29.4 15.0 5.3e-07 29.4 15.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX82067.1 - 7.2e-07 29.1 12.2 1.8e-06 27.8 12.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXX82067.1 - 5.3e-06 26.5 12.2 1.1e-05 25.4 12.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXX82067.1 - 9e-06 25.5 10.8 2.5e-05 24.0 10.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXX82067.1 - 1.9e-05 24.8 8.8 5e-05 23.5 8.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain DEAD PF00270.29 KXX82067.1 - 0.00045 20.0 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Rad50_zn_hook PF04423.14 KXX82067.1 - 0.0035 17.2 0.5 1.3 8.9 0.0 2.9 2 0 0 2 2 2 1 Rad50 zinc hook motif ResIII PF04851.15 KXX82067.1 - 0.0052 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit U-box PF04564.15 KXX82067.1 - 0.008 16.3 0.2 0.029 14.6 0.2 1.9 1 0 0 1 1 1 1 U-box domain zf-ANAPC11 PF12861.7 KXX82067.1 - 0.0082 16.2 4.8 0.019 15.0 4.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KXX82067.1 - 0.019 14.8 13.6 0.036 13.9 11.2 2.5 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXX82067.1 - 0.037 13.8 9.1 0.11 12.4 9.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KXX82067.1 - 0.041 13.7 4.0 0.11 12.4 4.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KXX82067.1 - 0.24 11.6 12.5 0.028 14.5 7.8 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 KXX82067.1 - 0.26 11.0 10.3 2.3 8.0 3.9 2.7 1 1 1 2 2 2 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 KXX82067.1 - 0.28 11.2 6.7 0.57 10.2 6.7 1.5 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 KXX82067.1 - 2.4 8.3 5.2 7 6.8 5.2 1.7 1 1 0 1 1 1 0 Double zinc ribbon Glyco_hydro_61 PF03443.14 KXX82068.1 - 4.4e-52 177.0 0.0 6.4e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cpn10 PF00166.21 KXX82069.1 - 4.2e-29 100.5 0.0 4.8e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.25 KXX82070.1 - 2.5e-47 161.5 0.0 5.7e-47 160.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX82070.1 - 6.4e-22 78.1 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXX82070.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXX82070.1 - 0.033 13.1 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L11 PF00298.19 KXX82071.1 - 2.5e-29 101.6 0.6 9.9e-29 99.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KXX82071.1 - 1.3e-26 92.2 0.2 2e-26 91.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 KXX82072.1 - 5.2e-63 211.8 0.0 9.7e-63 210.9 0.0 1.5 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KXX82072.1 - 1.9e-55 187.4 0.0 2.5e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Histone PF00125.24 KXX82073.1 - 0.0016 18.8 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXX82073.1 - 0.0046 17.0 0.0 0.0062 16.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KXX82073.1 - 0.0066 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXX82073.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AbiEi_4 PF13338.6 KXX82073.1 - 0.04 14.1 1.8 0.099 12.8 1.8 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin TFIID-31kDa PF02291.15 KXX82073.1 - 0.098 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Pho86 PF11124.8 KXX82074.1 - 0.0023 17.4 0.3 0.0034 16.9 0.3 1.2 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_1 PF00583.25 KXX82074.1 - 0.029 14.6 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AOX PF01786.17 KXX82075.1 - 6.7e-92 306.9 0.0 8.3e-92 306.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase CorA PF01544.18 KXX82076.1 - 0.37 10.1 6.4 1.5 8.1 5.9 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein GTA_holin_3TM PF11351.8 KXX82078.1 - 1.6 9.3 4.5 2.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release HD PF01966.22 KXX82079.1 - 0.0002 21.5 0.2 0.00041 20.5 0.2 1.5 1 1 0 1 1 1 1 HD domain APH PF01636.23 KXX82081.1 - 1.9e-35 122.9 0.1 2.8e-35 122.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KXX82081.1 - 0.036 13.3 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase DUF2263 PF10021.9 KXX82082.1 - 2e-18 67.1 0.6 7.9e-18 65.2 0.6 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) AAA PF00004.29 KXX82083.1 - 2.7e-16 60.2 0.0 4.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX82083.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 KXX82084.1 - 7.7e-12 45.5 0.1 9.6e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KXX82085.1 - 0.013 14.4 21.3 0.16 10.9 12.0 3.1 2 1 2 4 4 4 0 Major Facilitator Superfamily IncD PF17628.2 KXX82085.1 - 0.25 11.1 0.8 1.2 8.9 0.8 2.0 2 0 0 2 2 2 0 Inclusion membrane protein D GLTP PF08718.11 KXX82086.1 - 3e-47 160.6 0.0 7.6e-47 159.3 0.0 1.6 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) RNase_H PF00075.24 KXX82087.1 - 4.9e-18 65.7 0.0 8.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNase H HET PF06985.11 KXX82088.1 - 0.083 13.2 1.1 0.19 12.1 1.1 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Peptidase_U4 PF03419.13 KXX82089.1 - 1.5 8.1 5.1 2.3 7.4 5.1 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA PLDc_2 PF13091.6 KXX82091.1 - 1.8e-16 60.2 0.0 8.1e-06 25.8 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KXX82091.1 - 8.5e-16 57.4 1.5 1.8e-07 31.0 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif NMO PF03060.15 KXX82095.1 - 7.6e-57 193.2 0.1 1.2e-56 192.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXX82095.1 - 3.9e-11 42.6 0.3 7.5e-11 41.6 0.3 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXX82095.1 - 1.3e-06 27.7 1.2 1.9e-06 27.2 1.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXX82095.1 - 0.0021 17.3 0.5 0.0045 16.2 0.5 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NanE PF04131.14 KXX82095.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Pterin_bind PF00809.22 KXX82096.1 - 1.2e-71 241.3 0.0 1.7e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KXX82096.1 - 7.6e-36 123.0 0.0 2.3e-35 121.5 0.0 1.8 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PEP_mutase PF13714.6 KXX82096.1 - 0.072 12.5 0.4 0.26 10.7 0.2 1.9 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase MscL PF01741.18 KXX82097.1 - 2.9e-17 63.1 0.0 3.6e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.15 KXX82097.1 - 7.3e-05 22.7 1.6 0.00011 22.2 1.6 1.3 1 0 0 1 1 1 1 BED zinc finger C1_1 PF00130.22 KXX82097.1 - 0.036 13.9 1.3 0.056 13.3 1.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cwf_Cwc_15 PF04889.12 KXX82097.1 - 2.4 7.8 8.0 3.3 7.4 8.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SUR7 PF06687.12 KXX82098.1 - 6.9e-13 48.7 0.0 9e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family YjcB PF15940.5 KXX82098.1 - 0.017 15.3 0.5 0.037 14.2 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function MFS_1 PF07690.16 KXX82101.1 - 4.4e-36 124.5 36.8 4.4e-36 124.5 36.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily GDPD PF03009.17 KXX82102.1 - 6.5e-13 49.0 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SET PF00856.28 KXX82102.1 - 7e-12 46.0 0.1 4e-11 43.6 0.1 2.1 1 1 0 1 1 1 1 SET domain FAD_binding_4 PF01565.23 KXX82103.1 - 5.2e-22 78.1 0.5 5.2e-22 78.1 0.5 3.7 3 1 0 3 3 3 1 FAD binding domain BBE PF08031.12 KXX82103.1 - 8.8e-12 44.9 0.5 1.7e-11 44.0 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like Esterase PF00756.20 KXX82104.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase ABC_tran PF00005.27 KXX82105.1 - 1.5e-45 155.1 0.0 5.8e-24 85.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXX82105.1 - 1e-26 94.2 28.1 5.2e-26 91.9 9.1 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXX82105.1 - 8.6e-10 38.4 4.4 0.017 14.6 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXX82105.1 - 7.5e-09 35.8 1.3 0.002 18.0 0.0 3.4 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXX82105.1 - 9.2e-07 28.5 1.8 0.013 15.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXX82105.1 - 9.3e-06 26.3 0.2 0.024 15.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXX82105.1 - 3.5e-05 24.1 0.1 0.61 10.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXX82105.1 - 5.5e-05 23.6 0.0 0.029 14.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KXX82105.1 - 9.6e-05 22.0 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KXX82105.1 - 0.00018 21.6 0.4 0.68 10.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXX82105.1 - 0.00086 19.4 1.3 0.064 13.3 0.1 2.3 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KXX82105.1 - 0.0011 18.9 0.4 0.31 10.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KXX82105.1 - 0.0014 17.7 0.0 0.38 9.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXX82105.1 - 0.002 17.9 0.1 0.073 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KXX82105.1 - 0.0046 16.3 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AIG1 PF04548.16 KXX82105.1 - 0.0067 15.8 0.7 1.2 8.4 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_18 PF13238.6 KXX82105.1 - 0.011 16.3 0.6 6.7 7.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 KXX82105.1 - 0.014 15.1 0.2 1.4 8.6 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF87 PF01935.17 KXX82105.1 - 0.018 15.2 4.6 0.029 14.4 0.6 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_11 PF13086.6 KXX82105.1 - 0.032 14.0 0.0 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXX82105.1 - 0.05 13.4 0.8 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 KXX82105.1 - 0.052 13.3 0.2 11 5.7 0.0 3.4 4 0 0 4 4 4 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KXX82105.1 - 0.063 13.6 0.1 5.1 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXX82105.1 - 0.075 12.7 0.2 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 KXX82105.1 - 0.12 11.5 0.4 4.6 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 KXX82105.1 - 0.16 11.6 0.1 1.1 8.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXX82105.1 - 0.21 12.0 0.1 17 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KXX82105.1 - 0.25 11.0 0.1 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXX82105.1 - 0.28 10.4 0.3 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 KXX82105.1 - 2.7 7.9 6.5 12 5.8 0.1 3.2 3 0 0 3 3 3 0 NTPase HCO3_cotransp PF00955.21 KXX82106.1 - 1.2e-65 222.3 13.9 1.8e-39 135.9 6.5 2.7 1 1 1 2 2 2 2 HCO3- transporter family SET PF00856.28 KXX82107.1 - 9.6e-10 39.1 0.0 4.7e-09 36.9 0.0 1.9 1 1 1 2 2 2 1 SET domain DUF4748 PF15932.5 KXX82107.1 - 0.049 13.4 0.7 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) Putative_PNPOx PF01243.20 KXX82109.1 - 2.5e-05 24.4 0.0 5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.25 KXX82110.1 - 8.8e-20 71.0 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82110.1 - 1.5e-13 50.8 0.0 2e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82110.1 - 6.7e-05 22.9 0.0 7.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 KR domain BTG PF07742.12 KXX82110.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 BTG family Lipase_GDSL PF00657.22 KXX82111.1 - 8.3e-12 45.5 0.0 1.4e-11 44.8 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXX82111.1 - 1.3e-07 32.2 0.4 2e-07 31.6 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_76 PF03663.14 KXX82113.1 - 2.1e-134 448.6 5.9 2.4e-134 448.5 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 KXX82113.1 - 0.0028 16.2 0.3 0.039 12.4 0.0 2.1 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 KXX82113.1 - 0.0068 15.5 3.5 1.6 7.7 0.0 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 KXX82113.1 - 0.086 12.1 3.1 7.1 5.8 0.1 2.5 2 1 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Aminotran_1_2 PF00155.21 KXX82114.1 - 8.4e-62 209.4 0.0 1e-61 209.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SLATT_fungal PF18142.1 KXX82115.1 - 1.3e-10 41.3 0.1 6.3e-09 35.9 0.1 2.1 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Xpo1 PF08389.12 KXX82116.1 - 1.9e-27 96.1 0.1 9.2e-27 93.9 0.1 2.3 1 0 0 1 1 1 1 Exportin 1-like protein HEAT_EZ PF13513.6 KXX82116.1 - 0.00036 21.0 0.7 0.37 11.3 0.0 5.5 5 0 0 5 5 5 1 HEAT-like repeat IBN_N PF03810.19 KXX82116.1 - 0.0022 17.9 1.5 0.019 14.9 0.2 2.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain Death PF00531.22 KXX82116.1 - 0.069 13.3 0.2 1.1 9.4 0.0 3.1 3 0 0 3 3 3 0 Death domain NUC173 PF08161.12 KXX82116.1 - 0.07 12.8 2.0 44 3.6 0.0 4.9 6 0 0 6 6 6 0 NUC173 domain Adaptin_N PF01602.20 KXX82116.1 - 0.085 11.4 0.2 0.91 8.0 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region ABATE PF07336.11 KXX82116.1 - 0.09 13.4 4.0 0.2 12.3 0.1 2.9 2 0 0 2 2 2 0 Putative stress-induced transcription regulator RabGAP-TBC PF00566.18 KXX82117.1 - 6.2e-48 163.3 0.0 1.6e-47 162.0 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Leu_zip PF15294.6 KXX82117.1 - 0.00041 19.9 2.2 0.00041 19.9 2.2 2.5 3 0 0 3 3 3 1 Leucine zipper CENP-K PF11802.8 KXX82117.1 - 0.0019 17.8 8.1 0.51 9.9 6.5 2.5 2 0 0 2 2 2 2 Centromere-associated protein K DUF1664 PF07889.12 KXX82117.1 - 0.0028 17.7 4.9 0.0028 17.7 4.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KXX82117.1 - 0.014 15.6 7.7 0.014 15.6 7.7 3.2 4 0 0 4 4 4 0 Tropomyosin like DUF4763 PF15960.5 KXX82117.1 - 0.028 13.7 16.6 1.3 8.3 7.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) CpXC PF14353.6 KXX82117.1 - 0.43 10.6 1.4 0.93 9.6 0.0 2.2 2 0 0 2 2 2 0 CpXC protein AAA_13 PF13166.6 KXX82117.1 - 0.74 8.4 8.7 1.6 7.3 8.7 1.5 1 0 0 1 1 1 0 AAA domain DUF5340 PF17275.2 KXX82117.1 - 0.98 9.6 7.7 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5340) Tmemb_cc2 PF10267.9 KXX82117.1 - 1.8 7.6 21.8 0.02 14.1 1.3 3.0 3 0 0 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein DUF773 PF05600.12 KXX82117.1 - 7.6 5.1 11.5 0.84 8.3 5.0 2.2 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 Reticulon PF02453.17 KXX82118.1 - 6.8e-34 117.1 5.8 1e-33 116.5 5.8 1.3 1 0 0 1 1 1 1 Reticulon HET PF06985.11 KXX82120.1 - 5.6e-07 30.0 0.0 6.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Myelin-PO_C PF10570.9 KXX82120.1 - 0.099 13.1 0.0 0.36 11.3 0.0 1.9 1 1 1 2 2 2 0 Myelin-PO cytoplasmic C-term p65 binding region Yip1 PF04893.17 KXX82121.1 - 4.2e-13 49.4 16.6 4.2e-13 49.4 16.6 1.5 1 1 0 1 1 1 1 Yip1 domain QCR10 PF09796.9 KXX82121.1 - 0.15 12.2 0.8 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) ubiquitin PF00240.23 KXX82122.1 - 6.3e-33 112.3 0.6 1.2e-32 111.5 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KXX82122.1 - 4.4e-30 103.3 10.4 9.4e-30 102.3 10.4 1.6 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KXX82122.1 - 3.8e-15 55.5 0.7 7.2e-15 54.6 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RRN7 PF11781.8 KXX82122.1 - 5.9e-08 32.2 3.8 5.9e-08 32.2 3.8 2.3 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ubiquitin_2 PF14560.6 KXX82122.1 - 0.00028 21.3 0.2 0.00066 20.1 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXX82122.1 - 0.038 13.9 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXX82122.1 - 0.046 14.1 0.1 0.091 13.1 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXX82122.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pex24p PF06398.11 KXX82123.1 - 9.6e-100 334.1 0.0 1.2e-99 333.8 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin MIF4G PF02854.19 KXX82125.1 - 9.5e-60 201.8 0.0 1.8e-32 112.7 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KXX82125.1 - 3e-40 138.1 4.1 3e-40 138.1 4.1 2.5 2 0 0 2 2 2 1 Up-frameshift suppressor 2 CDC45 PF02724.14 KXX82125.1 - 0.15 10.4 6.1 0.36 9.1 6.1 1.6 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 KXX82125.1 - 0.55 10.2 12.3 0.55 10.2 7.3 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Chitin_synth_2 PF03142.15 KXX82126.1 - 4.3e-21 75.1 3.0 4.3e-21 75.1 3.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXX82126.1 - 1.1e-17 64.6 6.7 1.1e-17 64.6 6.7 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXX82126.1 - 6.1e-13 49.2 0.1 1.7e-12 47.7 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXX82126.1 - 0.017 15.0 0.3 7.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 MMS1_N PF10433.9 KXX82127.1 - 2.1e-54 185.0 0.0 3.8e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXX82127.1 - 0.0028 17.0 0.0 0.024 13.9 0.0 2.5 2 1 0 2 2 2 1 CPSF A subunit region RabGAP-TBC PF00566.18 KXX82128.1 - 9.1e-23 81.0 0.0 1.1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 KXX82130.1 - 5.3e-15 55.6 12.1 1.1e-07 32.4 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX82130.1 - 0.05 13.9 0.4 1.7 9.0 0.1 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4148 PF13663.6 KXX82130.1 - 0.29 11.3 2.3 15 5.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) PAS_3 PF08447.12 KXX82131.1 - 1.4e-17 63.7 0.0 7.1e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KXX82131.1 - 1.1e-11 44.9 0.0 1.4e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KXX82131.1 - 9.2e-09 35.3 0.0 0.0004 20.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KXX82131.1 - 3.1e-05 24.2 0.0 0.038 14.2 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KXX82131.1 - 0.0006 19.9 0.0 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KXX82131.1 - 0.0009 19.2 0.0 0.4 10.8 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_12 PF18095.1 KXX82131.1 - 0.044 13.4 0.0 5.6 6.6 0.0 2.2 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain Med13_C PF06333.12 KXX82131.1 - 0.16 11.2 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Yip1 PF04893.17 KXX82132.1 - 5.3e-12 45.8 17.4 8.6e-12 45.1 17.4 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KXX82132.1 - 0.0006 19.6 4.9 0.001 18.9 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF2070 PF09843.9 KXX82132.1 - 0.11 10.8 7.2 0.13 10.5 7.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Na_Ca_ex PF01699.24 KXX82133.1 - 1.3e-22 80.4 23.8 3.2e-14 53.1 6.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1298 PF06974.13 KXX82133.1 - 0.0056 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) COX2_TM PF02790.15 KXX82133.1 - 3.3 7.9 0.0 3.3 7.9 0.0 3.9 4 2 2 6 6 6 0 Cytochrome C oxidase subunit II, transmembrane domain DEAD PF00270.29 KXX82134.1 - 8.1e-28 97.4 0.0 1.5e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KXX82134.1 - 5.8e-20 71.8 0.3 1.4e-19 70.6 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KXX82134.1 - 4.8e-11 43.0 0.0 1.3e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX82134.1 - 7.7e-08 32.5 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KXX82134.1 - 0.039 14.3 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor CDT1 like Ran_BP1 PF00638.18 KXX82135.1 - 2.5e-11 43.9 0.2 0.00024 21.4 0.0 2.4 2 0 0 2 2 2 2 RanBP1 domain zf-RING_2 PF13639.6 KXX82136.1 - 1.1e-14 54.4 17.2 4e-13 49.5 8.3 2.2 2 0 0 2 2 2 2 Ring finger domain zf-RING_11 PF17123.5 KXX82136.1 - 1.1e-09 37.8 4.0 1.1e-09 37.8 4.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXX82136.1 - 4.2e-09 36.1 11.5 5.5e-08 32.5 5.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX82136.1 - 2.7e-08 33.5 7.2 2.7e-08 33.5 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KXX82136.1 - 3.2e-08 33.7 1.4 3.2e-08 33.7 1.4 2.3 2 0 0 2 2 2 1 zinc-ribbon zf-rbx1 PF12678.7 KXX82136.1 - 4.8e-07 30.0 13.7 9.3e-07 29.0 7.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXX82136.1 - 1.9e-06 27.7 16.1 4.5e-05 23.2 7.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX82136.1 - 3.1e-05 23.8 4.8 3.1e-05 23.8 4.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXX82136.1 - 9.1e-05 22.2 13.2 0.00026 20.8 5.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXX82136.1 - 0.00023 21.1 1.4 0.00023 21.1 1.4 2.6 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_1 PF14446.6 KXX82136.1 - 0.00054 19.8 10.7 0.23 11.4 1.9 3.2 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 KXX82136.1 - 0.0019 18.2 6.3 0.01 15.8 2.9 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 KXX82136.1 - 0.0024 17.5 2.4 0.0064 16.1 2.4 1.7 1 0 0 1 1 1 1 P-11 zinc finger HypA PF01155.19 KXX82136.1 - 0.016 15.2 0.3 0.016 15.2 0.3 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Baculo_RING PF05883.11 KXX82136.1 - 0.24 11.4 1.2 6.3 6.8 0.7 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Zn_ribbon_17 PF17120.5 KXX82136.1 - 0.57 9.8 14.5 0.59 9.8 6.9 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DNA_ligase_ZBD PF03119.16 KXX82136.1 - 0.78 9.8 3.3 26 5.0 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc-ribbons_6 PF07191.12 KXX82136.1 - 1.1 9.3 7.0 2.2 8.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 KXX82136.1 - 1.1 9.3 6.4 0.87 9.7 0.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 KXX82136.1 - 1.3 9.3 12.7 0.48 10.6 1.3 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KXX82136.1 - 2.5 8.1 14.3 4.6 7.2 6.2 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 KXX82136.1 - 4.5 7.2 12.0 1.2 9.0 4.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 KXX82136.1 - 5 6.7 5.6 5 6.7 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.11 KXX82136.1 - 5.6 7.1 7.4 2.7 8.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) FANCL_C PF11793.8 KXX82136.1 - 8.2 6.7 12.2 10 6.4 7.0 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain Fis1_TPR_C PF14853.6 KXX82137.1 - 1.1e-25 89.4 1.1 1.6e-25 88.9 1.1 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KXX82137.1 - 1.8e-16 59.5 0.0 2.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KXX82137.1 - 0.0016 18.4 1.2 0.0037 17.3 1.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3665 PF12427.8 KXX82137.1 - 1.2 8.9 0.1 1.2 8.9 0.1 2.2 3 0 0 3 3 3 0 Branched-chain amino acid aminotransferase p450 PF00067.22 KXX82138.1 - 9.9e-52 176.2 0.0 1.5e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.20 KXX82139.1 - 4.8e-15 56.0 0.0 8.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain CHASE5 PF17149.4 KXX82139.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins DASH_Ask1 PF08655.10 KXX82140.1 - 1.4e-30 104.9 0.2 2.2e-30 104.3 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 SR-25 PF10500.9 KXX82141.1 - 0.11 12.1 5.5 0.12 12.0 5.5 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GCP_C_terminal PF04130.13 KXX82142.1 - 2.6e-54 184.8 0.0 4.8e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXX82142.1 - 8e-29 101.2 0.0 1.5e-28 100.3 0.0 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Eaf7 PF07904.13 KXX82143.1 - 6.4e-28 97.2 0.0 6.4e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Pox_Ag35 PF03286.14 KXX82143.1 - 1.3 8.7 10.8 2.8 7.7 10.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 KXX82143.1 - 4.3 7.1 7.5 6.5 6.5 7.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 KXX82143.1 - 6.2 6.0 6.1 9.5 5.4 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Vint PF14623.6 KXX82144.1 - 3e-52 176.8 0.0 5.4e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KXX82144.1 - 3.6e-28 97.5 0.0 5.5e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KXX82144.1 - 2.6e-13 50.6 0.0 4.1e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXX82144.1 - 3.7e-11 43.6 0.0 2.2e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXX82144.1 - 5.7e-10 39.3 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1664 PF07889.12 KXX82145.1 - 0.0049 16.9 1.1 0.0088 16.1 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CRR7 PF12095.8 KXX82145.1 - 0.039 14.4 0.9 0.35 11.3 0.0 2.6 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Lant_dehydr_C PF14028.6 KXX82145.1 - 0.04 13.5 1.3 0.069 12.7 1.3 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF961 PF06125.11 KXX82145.1 - 0.04 14.3 0.2 0.092 13.1 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) DUF2120 PF09893.9 KXX82145.1 - 0.15 12.2 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) DUF16 PF01519.16 KXX82145.1 - 0.2 12.2 1.5 0.37 11.3 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF3584 PF12128.8 KXX82146.1 - 0.0014 16.3 2.7 0.0014 16.3 2.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) BicD PF09730.9 KXX82146.1 - 0.036 12.5 2.1 0.074 11.5 1.3 1.8 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D CSN5_C PF18323.1 KXX82146.1 - 0.075 14.0 9.4 3.5 8.6 5.3 2.6 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Spectrin PF00435.21 KXX82146.1 - 0.092 13.2 2.6 0.36 11.3 0.7 2.8 2 0 0 2 2 2 0 Spectrin repeat Tho2 PF11262.8 KXX82146.1 - 0.14 11.3 5.9 0.068 12.4 3.4 1.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF842 PF05811.13 KXX82146.1 - 1.9 8.2 6.8 0.4 10.4 0.9 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF966 PF06136.13 KXX82147.1 - 2.9 7.5 6.0 3.6 7.2 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ETC_C1_NDUFA5 PF04716.14 KXX82148.1 - 5.1e-26 90.3 6.1 5.8e-25 86.9 0.3 2.7 3 0 0 3 3 3 2 ETC complex I subunit conserved region Mo-co_dimer PF03404.16 KXX82149.1 - 6.6e-60 201.1 0.0 1.2e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KXX82149.1 - 1.9e-55 187.1 0.0 3.2e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KXX82149.1 - 8.3e-33 112.7 0.0 1.4e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXX82149.1 - 1.8e-27 96.1 0.0 3.8e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXX82149.1 - 5.6e-21 74.5 0.0 1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXX82149.1 - 0.0012 19.0 0.0 0.033 14.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain HSP70 PF00012.20 KXX82150.1 - 1e-165 552.3 7.0 3.5e-165 550.6 7.0 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXX82150.1 - 2.6e-10 39.7 0.0 2.3e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Trans_reg_C PF00486.28 KXX82150.1 - 0.14 12.3 0.0 0.59 10.3 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal GTP_EFTU PF00009.27 KXX82151.1 - 5.1e-35 120.8 0.8 1.2e-34 119.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXX82151.1 - 1.1e-19 70.5 0.0 2.7e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KXX82151.1 - 1.7e-09 37.4 0.2 9.5e-09 35.1 0.2 2.4 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KXX82151.1 - 1.2e-08 35.2 12.9 2.2e-07 31.1 0.1 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXX82151.1 - 1.5e-07 31.5 0.1 3.5e-06 27.1 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KXX82151.1 - 0.00014 22.0 0.0 0.00049 20.3 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KXX82151.1 - 0.0027 17.5 0.0 0.0027 17.5 0.0 2.2 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KXX82151.1 - 0.046 13.3 0.0 0.25 10.9 0.0 2.3 1 1 0 1 1 1 0 Ras family Vps52 PF04129.12 KXX82152.1 - 2.5e-121 405.9 0.0 3.1e-121 405.6 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KXX82152.1 - 5e-06 25.2 0.3 1.1e-05 24.1 0.3 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.10 KXX82152.1 - 0.0082 16.0 0.2 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 Mer2 Filament PF00038.21 KXX82152.1 - 0.027 14.0 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 KXX82152.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein eIF-5a PF01287.20 KXX82153.1 - 2.1e-29 101.4 1.3 2.8e-29 101.0 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KXX82153.1 - 0.00078 19.4 0.3 0.0028 17.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Dynamin_N PF00350.23 KXX82154.1 - 0.00085 19.4 0.1 0.00092 19.3 0.1 1.0 1 0 0 1 1 1 1 Dynamin family Cu-oxidase_3 PF07732.15 KXX82155.1 - 3.3e-26 91.6 0.0 3.9e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXX82155.1 - 0.00091 19.0 0.1 0.0039 16.9 0.1 1.8 1 1 0 1 1 1 1 Multicopper oxidase DUF3818 PF12825.7 KXX82156.1 - 1.9e-46 158.7 0.0 1.3e-25 90.2 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXX82156.1 - 4.1e-39 133.5 0.0 8.6e-39 132.5 0.0 1.6 1 0 0 1 1 1 1 PX-associated UBA_2 PF08587.11 KXX82156.1 - 0.021 14.9 0.5 0.068 13.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) YabA PF06156.13 KXX82158.1 - 0.28 11.8 2.7 0.71 10.5 2.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA BshC PF10079.9 KXX82158.1 - 0.69 8.6 7.6 1 8.0 7.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Thiolase_N PF00108.23 KXX82159.1 - 7.2e-68 228.7 2.0 9.4e-68 228.4 2.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX82159.1 - 2.1e-40 137.2 1.5 5.7e-40 135.8 1.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ABC_tran_CTD PF16326.5 KXX82162.1 - 2e-05 24.7 4.6 2e-05 24.7 4.6 5.9 4 2 2 6 6 6 1 ABC transporter C-terminal domain FapA PF03961.13 KXX82162.1 - 0.00073 18.3 9.8 0.00073 18.3 9.8 3.7 2 1 1 3 3 3 1 Flagellar Assembly Protein A DUF4407 PF14362.6 KXX82162.1 - 1.9 7.7 51.5 1.1 8.5 20.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Hemagglutinin PF00509.18 KXX82162.1 - 2.1 6.7 6.1 0.21 10.0 1.2 1.7 2 0 0 2 2 2 0 Haemagglutinin GTP1_OBG PF01018.22 KXX82164.1 - 2.4e-39 134.4 2.2 9.3e-29 100.0 4.8 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KXX82164.1 - 3.2e-23 82.0 0.0 5.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXX82164.1 - 5.3e-06 26.0 0.1 1.4e-05 24.7 0.1 1.6 1 1 1 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KXX82164.1 - 0.0071 15.4 0.0 0.46 9.4 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KXX82164.1 - 0.083 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 KXX82164.1 - 0.11 11.9 0.0 0.67 9.4 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KXX82164.1 - 0.19 12.3 0.4 0.77 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Methyltr_RsmB-F PF01189.17 KXX82165.1 - 9.7e-32 110.2 0.0 9.4e-25 87.4 0.0 3.0 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KXX82165.1 - 0.0096 16.0 0.0 0.025 14.7 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Presenilin PF01080.17 KXX82165.1 - 5.1 5.8 4.4 8.4 5.0 4.4 1.3 1 0 0 1 1 1 0 Presenilin FoP_duplication PF13865.6 KXX82165.1 - 9.3 6.9 12.9 0.57 10.8 7.3 1.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Fungal_trans PF04082.18 KXX82166.1 - 3e-23 82.2 0.2 4.5e-23 81.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF948 PF06103.11 KXX82166.1 - 0.16 12.2 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TatD_DNase PF01026.21 KXX82167.1 - 2.2e-28 99.3 0.0 3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Spc24 PF08286.11 KXX82169.1 - 9.6e-38 128.6 0.6 6.8e-36 122.7 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF1633 PF07794.11 KXX82169.1 - 0.0083 14.4 0.1 0.011 14.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) Exonuc_VII_L PF02601.15 KXX82169.1 - 0.023 14.3 1.3 0.028 14.0 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLZ PF16526.5 KXX82169.1 - 0.04 14.3 8.1 1.6 9.2 1.6 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MAGSP PF03082.14 KXX82169.1 - 0.059 13.0 0.7 0.086 12.4 0.7 1.3 1 0 0 1 1 1 0 Male accessory gland secretory protein DUF4337 PF14235.6 KXX82169.1 - 0.084 13.0 3.6 0.12 12.5 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Trimer_CC PF08954.11 KXX82169.1 - 0.086 12.4 5.8 1.7 8.2 2.3 2.4 2 0 0 2 2 2 0 Trimerisation motif APG6_N PF17675.1 KXX82169.1 - 0.12 12.9 10.5 0.19 12.3 10.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4164 PF13747.6 KXX82169.1 - 0.12 12.7 12.4 0.47 10.8 12.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3073 PF11273.8 KXX82169.1 - 0.12 13.1 1.8 0.18 12.6 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) Miff PF05644.11 KXX82169.1 - 0.16 11.6 3.5 0.22 11.1 3.5 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff FUSC PF04632.12 KXX82169.1 - 0.19 10.2 4.7 0.2 10.2 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Blo-t-5 PF11642.8 KXX82169.1 - 0.2 11.6 2.1 0.35 10.9 2.1 1.4 1 0 0 1 1 1 0 Mite allergen Blo t 5 Nsp1_C PF05064.13 KXX82169.1 - 0.2 11.4 3.9 5.9 6.7 1.8 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF5082 PF16888.5 KXX82169.1 - 0.38 11.0 3.6 1.5 9.1 3.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) SlyX PF04102.12 KXX82169.1 - 0.41 11.3 6.8 1 10.0 1.5 2.6 1 1 0 2 2 2 0 SlyX GAS PF13851.6 KXX82169.1 - 0.42 9.9 7.5 0.84 9.0 7.5 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 KXX82169.1 - 1.1 9.2 5.5 1.2 9.1 1.7 2.2 1 1 1 2 2 2 0 Prefoldin subunit THOC7 PF05615.13 KXX82169.1 - 1.2 9.4 10.3 3.7 7.8 10.3 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 DUF1690 PF07956.11 KXX82169.1 - 2.6 8.5 8.6 22 5.4 8.6 2.0 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) ABC_tran_CTD PF16326.5 KXX82169.1 - 2.8 8.3 10.1 27 5.1 10.1 2.4 1 1 0 1 1 1 0 ABC transporter C-terminal domain ADIP PF11559.8 KXX82169.1 - 3.6 7.6 11.0 4 7.5 5.7 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KXX82169.1 - 3.7 6.4 8.9 8.5 5.2 8.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein M PF02370.16 KXX82169.1 - 4.2 8.3 6.0 60 4.7 3.1 2.8 2 0 0 2 2 2 0 M protein repeat Claudin_3 PF06653.11 KXX82170.1 - 0.31 11.0 3.4 3.2 7.7 0.2 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like RNA_pol_Rpb5_C PF01191.19 KXX82171.1 - 1.1e-33 114.9 0.8 2.3e-33 113.9 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KXX82171.1 - 5.3e-29 100.6 0.0 8.3e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KXX82171.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease AAA_3 PF07726.11 KXX82171.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GMC_oxred_N PF00732.19 KXX82172.1 - 1.2e-51 175.9 0.3 5.4e-51 173.7 0.3 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX82172.1 - 7.5e-27 94.6 0.0 1.4e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXX82172.1 - 8.6e-06 25.6 1.1 4.6e-05 23.2 1.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX82172.1 - 8.1e-05 21.9 0.0 0.0019 17.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXX82172.1 - 9.5e-05 22.6 0.2 0.0003 20.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX82172.1 - 0.0011 18.3 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX82172.1 - 0.0035 16.6 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXX82172.1 - 0.0039 16.5 0.2 0.22 10.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX82172.1 - 0.052 12.2 0.0 0.53 8.9 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.25 KXX82173.1 - 8.6e-21 74.3 0.0 2.9e-18 66.0 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82173.1 - 5.3e-13 49.1 0.0 3.6e-11 43.1 0.0 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82173.1 - 5.1e-07 29.8 0.1 7.3e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXX82173.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXX82173.1 - 0.015 14.5 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXX82173.1 - 0.016 14.6 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXX82173.1 - 0.054 13.5 0.1 0.077 13.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXX82173.1 - 0.095 13.3 0.2 0.2 12.2 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KXX82173.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KXX82173.1 - 0.17 12.0 0.1 0.42 10.8 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.12 KXX82173.1 - 0.19 10.9 0.1 0.46 9.6 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein FAD_binding_4 PF01565.23 KXX82174.1 - 1.5e-19 70.1 2.3 2.7e-19 69.3 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX82174.1 - 1e-10 41.5 0.6 2.2e-10 40.5 0.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like MscL PF01741.18 KXX82175.1 - 0.084 13.2 0.2 0.084 13.2 0.2 2.1 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL ketoacyl-synt PF00109.26 KXX82176.1 - 2.6e-74 250.0 0.0 7e-74 248.6 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX82176.1 - 6.4e-55 185.9 0.8 1.9e-53 181.1 0.0 3.1 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KXX82176.1 - 2.9e-41 142.0 0.0 6.3e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXX82176.1 - 1e-38 133.3 0.1 2e-38 132.3 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXX82176.1 - 6.9e-29 100.3 0.1 4.8e-27 94.3 0.0 3.4 4 0 0 4 4 3 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXX82176.1 - 2.3e-25 89.3 0.0 4.7e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KXX82176.1 - 1.3e-18 67.5 0.0 3.9e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX82176.1 - 1.1e-13 51.0 0.0 7.1e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXX82176.1 - 2.7e-12 47.2 0.0 1.2e-11 45.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXX82176.1 - 1.6e-11 44.7 0.0 3.9e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KXX82176.1 - 1.3e-10 41.3 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82176.1 - 2.5e-10 40.8 0.0 1.7e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX82176.1 - 2.8e-10 40.3 0.0 7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXX82176.1 - 3.7e-09 36.4 0.0 4.1e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 KXX82176.1 - 4.2e-07 29.5 0.0 8.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KXX82176.1 - 5.9e-07 29.3 0.1 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXX82176.1 - 2.5e-05 23.8 0.1 5.7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KXX82176.1 - 0.00055 20.2 0.2 0.0017 18.7 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 KXX82176.1 - 0.016 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase HTH_38 PF13936.6 KXX82176.1 - 0.017 14.8 3.4 1.6 8.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain ACP_syn_III PF08545.10 KXX82176.1 - 0.036 13.9 1.0 0.12 12.3 0.5 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NodS PF05401.11 KXX82176.1 - 0.05 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) GDP_Man_Dehyd PF16363.5 KXX82176.1 - 0.11 11.8 0.0 13 5.0 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KXX82178.1 - 0.0006 19.8 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX82178.1 - 0.0013 18.6 0.0 0.0086 15.9 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3636 PF12331.8 KXX82179.1 - 3.5e-46 156.7 0.0 7e-46 155.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) HTH_IclR PF09339.10 KXX82179.1 - 0.25 11.1 3.2 0.73 9.7 3.2 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF4407 PF14362.6 KXX82179.1 - 1 8.6 6.6 2.3 7.5 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CEP63 PF17045.5 KXX82179.1 - 1.2 9.0 7.4 0.42 10.5 3.7 1.9 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF287 PF03384.14 KXX82179.1 - 5.7 7.4 7.3 0.9 10.0 0.1 2.6 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 LCD1 PF09798.9 KXX82179.1 - 9.2 4.6 6.6 1.6 7.1 0.1 2.6 3 0 0 3 3 3 0 DNA damage checkpoint protein CTP_transf_1 PF01148.20 KXX82180.1 - 3.2e-77 259.9 23.8 4e-77 259.6 23.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2304 PF10066.9 KXX82180.1 - 2.3 8.5 13.6 10 6.4 0.6 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Thiolase_N PF00108.23 KXX82181.1 - 1.2e-65 221.5 0.1 1.7e-65 221.0 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX82181.1 - 5.5e-40 135.8 0.2 1.1e-39 134.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXX82181.1 - 0.11 12.1 1.4 0.32 10.5 0.6 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain EF-hand_10 PF14788.6 KXX82181.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 EF hand Glyco_hydro_cc PF11790.8 KXX82182.1 - 1.3e-72 244.3 0.1 1.4e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core adh_short PF00106.25 KXX82183.1 - 2.3e-25 89.2 0.0 7.8e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82183.1 - 3.2e-14 53.0 0.0 7.4e-14 51.9 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82183.1 - 1.3e-10 41.5 0.1 1.9e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX82183.1 - 0.00029 20.4 0.0 0.0004 19.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXX82183.1 - 0.0018 18.5 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXX82183.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Dynamin_N PF00350.23 KXX82184.1 - 3e-30 105.5 0.1 7.2e-30 104.2 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KXX82184.1 - 1.4e-11 44.1 0.0 2.8e-10 39.9 0.0 2.6 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KXX82184.1 - 2.9e-05 24.1 0.0 8.3e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXX82184.1 - 0.011 16.3 0.0 0.047 14.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MLTR_LBD PF17765.1 KXX82184.1 - 0.053 13.7 1.4 0.18 11.9 0.2 2.5 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain GED PF02212.18 KXX82184.1 - 0.061 13.5 1.7 0.18 12.0 1.7 1.8 1 0 0 1 1 1 0 Dynamin GTPase effector domain AAA_23 PF13476.6 KXX82184.1 - 0.11 12.9 0.1 2.7 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain KI67R PF08065.12 KXX82184.1 - 0.28 11.8 4.4 0.93 10.1 4.4 1.9 1 0 0 1 1 1 0 KI67R (NUC007) repeat Metal_resist PF13801.6 KXX82184.1 - 0.3 11.3 0.1 0.3 11.3 0.1 3.7 3 0 0 3 3 3 0 Heavy-metal resistance MFS_1 PF07690.16 KXX82185.1 - 1e-23 83.9 36.9 3.7e-23 82.0 33.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Transport_MerF PF11431.8 KXX82185.1 - 3.8 7.5 9.3 6.3 6.8 0.5 3.2 3 0 0 3 3 3 0 Membrane transport protein MerF RSN1_7TM PF02714.15 KXX82187.1 - 3.3e-76 256.2 24.6 6.6e-76 255.2 24.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXX82187.1 - 7.8e-40 137.0 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KXX82187.1 - 3e-38 131.0 0.5 3e-38 131.0 0.5 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Imm3 PF14425.6 KXX82187.1 - 0.043 13.9 0.1 0.076 13.1 0.1 1.3 1 0 0 1 1 1 0 Immunity protein Imm3 Trehalose_PPase PF02358.16 KXX82188.1 - 9.1e-46 155.9 0.0 1.4e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Aminotran_4 PF01063.19 KXX82188.1 - 4.8e-21 75.7 0.0 7.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV WD40 PF00400.32 KXX82190.1 - 6.4e-58 191.4 37.3 5.9e-11 42.8 0.8 9.4 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX82190.1 - 2.9e-21 75.5 5.6 0.0031 17.8 0.0 6.2 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXX82190.1 - 3.7e-07 30.2 0.8 0.00048 20.1 0.1 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXX82190.1 - 3.6e-05 22.9 0.0 1.1 8.2 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXX82190.1 - 0.0013 17.5 0.1 22 3.6 0.0 4.4 4 1 1 5 5 5 0 Nucleoporin Nup120/160 PD40 PF07676.12 KXX82190.1 - 0.026 14.5 0.3 4.3 7.4 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1707 PF08044.11 KXX82190.1 - 0.03 14.4 0.2 0.03 14.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) FAD_binding_9 PF08021.11 KXX82190.1 - 0.1 12.8 0.0 0.81 9.9 0.0 2.4 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain NLE PF08154.12 KXX82190.1 - 0.14 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain WD40_like PF17005.5 KXX82190.1 - 0.21 10.9 0.0 8.8 5.6 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain Glyco_transf_20 PF00982.21 KXX82191.1 - 2.7e-157 524.2 0.0 3.4e-157 523.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KXX82191.1 - 0.0075 16.0 0.3 0.013 15.2 0.3 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain LAP2alpha PF11560.8 KXX82191.1 - 0.086 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha TPR_2 PF07719.17 KXX82192.1 - 3.2e-11 42.4 13.7 0.0001 22.1 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXX82192.1 - 8.8e-10 38.0 5.2 0.013 15.7 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX82192.1 - 2e-09 37.9 3.6 2e-09 37.9 3.6 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXX82192.1 - 2.5e-09 36.5 7.8 0.0037 17.0 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX82192.1 - 1.6e-05 25.1 7.3 0.022 15.1 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX82192.1 - 3.7e-05 24.1 2.8 0.0072 16.8 1.6 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXX82192.1 - 0.0034 18.1 20.0 0.03 15.1 0.6 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXX82192.1 - 0.0044 17.3 0.9 0.22 12.0 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXX82192.1 - 0.0061 16.5 2.5 0.094 12.8 0.1 3.8 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXX82192.1 - 0.037 14.7 5.4 34 5.4 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXX82192.1 - 0.037 13.7 3.9 3.9 7.1 0.9 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KXX82192.1 - 0.12 12.5 3.9 0.76 10.0 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KXX82192.1 - 0.32 10.7 2.2 7.2 6.3 0.4 3.6 4 1 1 5 5 5 0 26S proteasome subunit RPN7 TPR_11 PF13414.6 KXX82192.1 - 1.5 8.5 3.3 15 5.4 0.0 3.9 2 1 1 3 3 3 0 TPR repeat Mg_chelatase_C PF13335.6 KXX82192.1 - 2.3 8.9 5.1 10 6.8 1.2 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal WxL PF13731.6 KXX82193.1 - 0.026 14.5 0.5 0.077 13.0 0.4 1.8 2 0 0 2 2 2 0 WxL domain surface cell wall-binding MARVEL PF01284.23 KXX82194.1 - 4.6e-09 36.4 9.7 6.4e-09 36.0 9.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3094 PF11293.8 KXX82194.1 - 0.27 11.0 1.5 14 5.5 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Peptidase_U4 PF03419.13 KXX82194.1 - 0.3 10.3 2.2 0.38 10.0 2.2 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Glyco_hydro_43 PF04616.14 KXX82195.1 - 9.5e-106 353.3 1.2 1.3e-105 352.9 0.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXX82195.1 - 1.2e-45 155.7 0.0 1.7e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Methyltransf_31 PF13847.6 KXX82196.1 - 2.6e-29 102.0 0.0 3.7e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82196.1 - 2.8e-24 85.6 0.0 4.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82196.1 - 3.9e-23 82.0 0.0 8.4e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX82196.1 - 1.2e-15 57.5 0.0 2.6e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXX82196.1 - 1.5e-15 57.7 0.0 2.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX82196.1 - 7e-13 48.7 0.0 9.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXX82196.1 - 3.1e-07 30.4 0.0 4.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KXX82196.1 - 4.1e-07 29.5 0.0 6.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KXX82196.1 - 9e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXX82196.1 - 1.2e-05 24.8 0.0 2.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 KXX82196.1 - 4.2e-05 23.6 0.0 6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXX82196.1 - 6.2e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW GCD14 PF08704.10 KXX82196.1 - 0.00066 19.4 0.0 0.00092 19.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.10 KXX82196.1 - 0.00091 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 KXX82196.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_9 PF08003.11 KXX82196.1 - 0.0032 16.4 0.0 0.0042 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF938 PF06080.12 KXX82196.1 - 0.0037 17.0 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.13 KXX82196.1 - 0.0042 16.5 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 KXX82196.1 - 0.0055 17.7 0.1 0.014 16.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.18 KXX82196.1 - 0.0066 16.2 0.0 0.024 14.3 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 CheR PF01739.18 KXX82196.1 - 0.0071 15.8 0.0 2.6 7.5 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 KXX82196.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KXX82196.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 KXX82196.1 - 0.039 12.5 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Met_10 PF02475.16 KXX82196.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein GidB PF02527.15 KXX82196.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G p450 PF00067.22 KXX82197.1 - 1.3e-33 116.4 0.0 5e-30 104.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Pex24p PF06398.11 KXX82197.1 - 0.034 13.1 0.5 0.047 12.7 0.5 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin adh_short_C2 PF13561.6 KXX82198.1 - 2.6e-51 174.5 2.4 3.4e-51 174.1 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX82198.1 - 1.3e-49 168.3 0.2 1.9e-49 167.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX82198.1 - 2.8e-12 46.9 0.1 1e-11 45.1 0.1 1.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXX82198.1 - 0.053 13.0 0.3 0.12 11.8 0.3 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LXG PF04740.12 KXX82199.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily Cutinase PF01083.22 KXX82200.1 - 1.3e-56 191.3 4.9 1.5e-56 191.1 4.9 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXX82200.1 - 2.3e-06 27.4 0.1 3e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 KXX82200.1 - 0.012 16.2 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX82200.1 - 0.013 15.2 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold VirJ PF06057.11 KXX82200.1 - 0.07 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Palm_thioest PF02089.15 KXX82200.1 - 0.1 12.4 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase p450 PF00067.22 KXX82201.1 - 4.6e-60 203.7 0.0 6.3e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 KXX82201.1 - 0.12 12.1 0.1 0.64 9.7 0.0 1.9 2 0 0 2 2 2 0 TUP1-like enhancer of split ADP_ribosyl_GH PF03747.14 KXX82202.1 - 3e-65 220.9 7.2 3.4e-65 220.7 7.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.15 KXX82202.1 - 0.062 13.2 2.3 5.2 7.0 0.8 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Sulfate_transp PF00916.20 KXX82204.1 - 1.3e-79 267.7 6.7 1.8e-79 267.3 6.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXX82204.1 - 9.5e-17 60.7 0.0 2.3e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 KXX82204.1 - 0.0031 17.8 0.0 0.0077 16.6 0.0 1.8 1 0 0 1 1 1 1 STAS domain WBS28 PF15164.6 KXX82204.1 - 0.07 12.4 0.2 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF1286 PF06939.11 KXX82204.1 - 0.12 12.7 0.8 7.2 6.9 0.1 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1286) MFS_MOT1 PF16983.5 KXX82204.1 - 0.84 10.1 10.5 0.075 13.4 4.0 2.4 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Fungal_trans_2 PF11951.8 KXX82205.1 - 1.8e-29 102.7 0.0 2.6e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82205.1 - 4.7e-05 23.4 9.1 8.6e-05 22.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 KXX82206.1 - 1.2e-29 103.6 0.0 3.8e-29 102.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase zf-RING_2 PF13639.6 KXX82206.1 - 0.00048 20.4 1.1 0.00048 20.4 1.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXX82206.1 - 0.00059 19.7 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXX82206.1 - 0.0015 18.4 0.1 0.005 16.7 0.1 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXX82206.1 - 0.0019 18.4 2.4 0.0046 17.2 2.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KXX82206.1 - 0.019 14.8 0.3 0.019 14.8 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX82206.1 - 0.059 13.4 0.8 0.2 11.7 0.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Peptidase_S11 PF00768.20 KXX82206.1 - 0.096 12.1 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Pellino PF04710.14 KXX82206.1 - 0.11 11.1 0.2 0.17 10.5 0.2 1.2 1 0 0 1 1 1 0 Pellino zf-RING_5 PF14634.6 KXX82206.1 - 0.14 12.1 0.1 0.37 10.8 0.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain PAD PF03068.15 KXX82207.1 - 1.1e-112 376.9 0.0 1.4e-112 376.5 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) TyeA PF09059.10 KXX82207.1 - 0.14 12.3 0.0 1.5 9.0 0.0 2.4 3 0 0 3 3 3 0 TyeA Dockerin_1 PF00404.18 KXX82207.1 - 0.19 12.0 0.6 4.5 7.6 0.0 3.0 3 0 0 3 3 3 0 Dockerin type I domain DUF4360 PF14273.6 KXX82208.1 - 4.8e-45 153.6 0.3 5.7e-45 153.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) GYF PF02213.16 KXX82209.1 - 6.6e-17 60.9 0.3 1.4e-16 59.9 0.3 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXX82209.1 - 0.087 12.6 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 GYF domain 2 SnoaL PF07366.12 KXX82210.1 - 0.0025 17.6 0.0 0.0061 16.4 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.18 KXX82210.1 - 0.086 12.4 0.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Acetyltransf_1 PF00583.25 KXX82211.1 - 2e-14 53.8 0.0 2.3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXX82211.1 - 1.3e-08 34.6 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXX82211.1 - 3.1e-07 30.7 0.0 4.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX82211.1 - 3.5e-06 27.0 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXX82211.1 - 0.0093 16.6 0.0 0.016 15.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXX82211.1 - 0.12 12.5 0.0 1.6 8.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXX82211.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Complex1_LYR PF05347.15 KXX82212.1 - 9.9e-09 35.1 0.5 2e-08 34.2 0.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXX82212.1 - 0.0033 18.2 0.6 0.0033 18.2 0.6 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KXX82212.1 - 0.0098 16.5 2.3 0.82 10.3 0.1 2.4 2 0 0 2 2 2 2 Complex1_LYR-like DUF2678 PF10856.8 KXX82213.1 - 2.3 8.2 10.5 0.42 10.5 1.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) 5_nucleotid_C PF02872.18 KXX82214.1 - 2.3e-39 135.1 0.0 4.6e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXX82214.1 - 2.1e-05 25.1 0.0 3.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FYVE PF01363.21 KXX82215.1 - 2.1e-22 79.0 23.7 3.3e-17 62.4 5.9 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KXX82215.1 - 9.9e-18 63.6 2.4 2.4e-17 62.4 2.4 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KXX82215.1 - 0.00033 20.7 2.8 0.00033 20.7 2.8 3.8 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KXX82215.1 - 0.11 12.8 12.8 0.15 12.4 0.1 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXX82215.1 - 0.62 11.1 0.0 0.62 11.1 0.0 6.3 5 1 1 6 6 6 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXX82215.1 - 0.73 10.2 0.0 0.73 10.2 0.0 3.7 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KXX82215.1 - 1.1 9.1 6.3 11 6.0 0.0 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) CtIP_N PF10482.9 KXX82215.1 - 2.2 8.4 9.0 2.4 8.2 0.1 3.1 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Csm1_N PF18504.1 KXX82215.1 - 4.8 7.6 6.3 26 5.2 0.9 2.9 2 1 0 2 2 2 0 Csm1 N-terminal domain CENP-L PF13092.6 KXX82216.1 - 7e-54 182.4 0.0 1.2e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Ank_4 PF13637.6 KXX82217.1 - 1.4e-16 60.6 0.4 2.2e-08 34.5 0.1 4.6 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX82217.1 - 9.9e-12 45.3 0.0 0.00088 19.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX82217.1 - 3.7e-11 42.2 0.2 0.00058 20.1 0.0 4.7 5 0 0 5 5 4 2 Ankyrin repeat Ank PF00023.30 KXX82217.1 - 1.6e-10 40.9 0.5 0.0013 19.0 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXX82217.1 - 4.5e-08 33.2 0.3 0.013 15.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KXX82217.1 - 2.2e-05 24.3 0.1 0.00018 21.3 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Exonuc_VII_L PF02601.15 KXX82217.1 - 0.046 13.3 3.5 0.079 12.5 3.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 KXX82217.1 - 0.048 13.7 3.6 0.096 12.7 3.6 1.4 1 0 0 1 1 1 0 Laminin Domain II USP8_interact PF08941.10 KXX82217.1 - 0.078 12.8 3.2 0.17 11.7 3.2 1.5 1 0 0 1 1 1 0 USP8 interacting TATR PF03430.13 KXX82217.1 - 0.13 10.6 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator MIF4G_like_2 PF09090.11 KXX82217.1 - 0.32 10.4 3.0 0.69 9.3 3.0 1.5 1 0 0 1 1 1 0 MIF4G like FliJ PF02050.16 KXX82217.1 - 0.33 11.2 14.3 0.069 13.4 10.4 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein Tmemb_cc2 PF10267.9 KXX82217.1 - 0.54 9.3 8.4 0.0097 15.1 1.5 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF3734 PF12536.8 KXX82217.1 - 0.71 10.2 3.1 3.2 8.1 1.2 2.5 2 0 0 2 2 2 0 Patatin phospholipase DUF5082 PF16888.5 KXX82217.1 - 6 7.2 8.9 9.3 6.5 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) NAD_binding_7 PF13241.6 KXX82218.1 - 1.3e-33 115.5 0.0 1.9e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KXX82218.1 - 3.9e-28 96.9 0.0 6e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KXX82218.1 - 2.3e-15 55.7 0.1 3.8e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KXX82218.1 - 0.00025 20.4 0.0 0.00033 20.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXX82218.1 - 0.00064 19.8 0.0 0.00097 19.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KXX82218.1 - 0.0066 15.8 0.4 0.04 13.3 0.0 2.0 2 0 0 2 2 2 1 ThiF family LSDAT_prok PF18171.1 KXX82218.1 - 0.014 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote AlaDh_PNT_C PF01262.21 KXX82218.1 - 0.11 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_S8 PF00082.22 KXX82219.1 - 7.1e-06 25.5 0.2 0.058 12.7 0.0 2.8 2 1 0 2 2 2 2 Subtilase family ThrE PF06738.12 KXX82219.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter HET PF06985.11 KXX82220.1 - 2.4e-20 73.4 0.1 5.1e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Arg_decarb_HB PF17810.1 KXX82220.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain Aldedh PF00171.22 KXX82221.1 - 7.8e-170 565.3 0.1 8.9e-170 565.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RhodobacterPufX PF11511.8 KXX82222.1 - 0.069 12.8 0.1 0.28 10.8 0.1 2.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF4337 PF14235.6 KXX82222.1 - 1.2 9.3 4.0 0.43 10.7 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TBX PF12598.8 KXX82223.1 - 0.14 13.0 2.5 0.19 12.6 0.9 1.8 2 0 0 2 2 2 0 T-box transcription factor Sec3_C PF09763.9 KXX82224.1 - 0.27 9.6 0.8 0.38 9.1 0.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 tRNA-synt_2 PF00152.20 KXX82225.1 - 4.9e-61 206.5 0.0 7.4e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXX82225.1 - 2.5e-10 40.2 0.0 4.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXX82225.1 - 6.4e-06 25.8 0.1 0.0035 16.9 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 KXX82226.1 - 3.9e-17 61.6 1.7 4.5e-17 61.5 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KXX82226.1 - 0.0091 15.7 2.3 0.012 15.3 2.3 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) HATPase_c PF02518.26 KXX82227.1 - 3.2e-22 79.2 0.0 6.6e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXX82227.1 - 1e-17 64.3 0.1 1.2e-13 51.2 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain PAS_4 PF08448.10 KXX82227.1 - 1.6e-08 34.8 0.0 0.00017 21.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 KXX82227.1 - 2.2e-06 27.6 1.8 3.8e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KXX82227.1 - 5.5e-06 26.4 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXX82227.1 - 2.8e-05 24.3 0.0 0.0002 21.6 0.0 2.5 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 KXX82227.1 - 0.00011 22.1 0.0 0.00062 19.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 KXX82227.1 - 0.00025 21.3 0.4 0.0022 18.3 0.1 2.3 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 KXX82227.1 - 0.067 13.5 0.0 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.6 KXX82227.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 GAF domain PH_6 PF15406.6 KXX82228.1 - 1.7e-47 160.3 4.5 1.7e-47 160.3 4.5 4.6 4 1 1 5 5 5 1 Pleckstrin homology domain PH PF00169.29 KXX82228.1 - 0.00016 22.2 0.0 0.0005 20.5 0.0 2.0 1 1 0 1 1 1 1 PH domain PH_4 PF15404.6 KXX82228.1 - 0.6 9.9 0.0 0.6 9.9 0.0 3.8 3 1 0 4 4 4 0 Pleckstrin homology domain Ost5 PF05251.12 KXX82229.1 - 3e-20 72.3 11.6 3.5e-20 72.1 11.6 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 KXX82230.1 - 6.7e-74 248.4 0.0 7.7e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Mago-bind PF09282.10 KXX82231.1 - 4.1e-15 55.3 3.1 9.2e-15 54.2 3.1 1.6 1 0 0 1 1 1 1 Mago binding DUF935 PF06074.12 KXX82231.1 - 0.068 11.9 6.3 0.079 11.7 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) RR_TM4-6 PF06459.12 KXX82231.1 - 0.46 10.3 14.2 0.53 10.1 14.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cellulose_synt PF03552.14 KXX82231.1 - 0.69 8.3 2.1 0.86 8.0 2.1 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4407 PF14362.6 KXX82231.1 - 4.9 6.4 8.9 5.3 6.3 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 KXX82231.1 - 7.3 6.6 5.2 8.4 6.4 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UCR_UQCRX_QCR9 PF05365.12 KXX82232.1 - 1.4e-27 95.4 1.4 1.6e-27 95.2 1.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like hGDE_N PF14699.6 KXX82232.1 - 0.16 12.1 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme IQ PF00612.27 KXX82233.1 - 2.2e-06 27.0 1.2 7.4e-06 25.3 1.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif SR-25 PF10500.9 KXX82233.1 - 0.0027 17.4 7.8 0.0027 17.4 7.8 3.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein ABC_tran PF00005.27 KXX82234.1 - 2.4e-31 109.1 0.0 4.8e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXX82234.1 - 1e-15 58.1 9.0 1e-15 58.1 9.0 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KXX82234.1 - 7.8e-08 32.0 0.0 8.9e-07 28.6 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXX82234.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXX82234.1 - 0.0039 16.5 0.0 0.0082 15.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 KXX82234.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KXX82234.1 - 0.0089 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KXX82234.1 - 0.013 16.0 0.1 0.029 14.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KXX82234.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXX82234.1 - 0.076 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KXX82234.1 - 0.088 13.2 0.2 0.67 10.4 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXX82234.1 - 0.11 12.0 0.9 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KXX82234.1 - 0.12 12.1 0.3 0.35 10.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXX82234.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1449 PF07290.11 KXX82234.1 - 0.21 11.2 0.1 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) Questin_oxidase PF14027.6 KXX82234.1 - 0.28 10.7 1.5 0.47 9.9 0.5 1.8 2 0 0 2 2 2 0 Questin oxidase-like PX PF00787.24 KXX82235.1 - 7.4e-21 74.2 0.0 1.3e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 PX domain adh_short PF00106.25 KXX82236.1 - 4e-35 121.1 0.2 5.6e-35 120.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82236.1 - 3e-27 95.7 3.1 4.1e-27 95.3 3.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82236.1 - 3.4e-11 43.4 0.3 5.8e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXX82236.1 - 1.9e-07 31.2 1.4 1.9e-07 31.2 1.4 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXX82236.1 - 3.1e-07 30.1 0.2 4e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXX82236.1 - 0.00024 20.3 1.1 0.00047 19.4 1.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KXX82236.1 - 0.0012 18.5 0.4 0.0023 17.5 0.4 1.5 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXX82236.1 - 0.0033 17.7 0.3 0.0061 16.8 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXX82236.1 - 0.01 16.1 0.5 0.027 14.7 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain DUF1776 PF08643.10 KXX82236.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ribosomal_S11 PF00411.19 KXX82237.1 - 1.3e-10 41.7 0.0 2.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 BCS1_N PF08740.11 KXX82238.1 - 1.2e-40 139.5 0.1 1.7e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXX82238.1 - 1.7e-20 73.8 0.0 2.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX82238.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX82238.1 - 7.5e-05 23.2 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXX82238.1 - 0.00016 21.7 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX82238.1 - 0.00041 20.6 0.0 0.00089 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXX82238.1 - 0.00042 19.9 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KXX82238.1 - 0.0036 16.5 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXX82238.1 - 0.0054 17.3 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXX82238.1 - 0.0069 16.1 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXX82238.1 - 0.015 14.9 0.1 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXX82238.1 - 0.019 15.4 0.1 2 8.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 KXX82238.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXX82238.1 - 0.034 14.1 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KXX82238.1 - 0.034 14.3 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KXX82238.1 - 0.039 14.4 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KXX82238.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXX82238.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KXX82238.1 - 0.06 13.9 0.0 0.15 12.6 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA_3 PF07726.11 KXX82238.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXX82238.1 - 0.12 12.7 1.3 1.7 9.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_6 PF12774.7 KXX82238.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_21 PF13304.6 KXX82238.1 - 0.13 12.0 0.3 0.75 9.5 0.0 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 KXX82238.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PPV_E1_C PF00519.17 KXX82238.1 - 0.16 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase IstB_IS21 PF01695.17 KXX82238.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KXX82238.1 - 0.28 10.3 0.0 0.43 9.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain DUF1768 PF08719.11 KXX82239.1 - 1.1e-48 165.5 0.0 1.3e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tim44 PF04280.15 KXX82240.1 - 1.3e-35 122.6 0.0 1.3e-35 122.6 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain PPL5 PF18168.1 KXX82240.1 - 0.25 10.6 13.0 0.53 9.5 13.0 1.5 1 0 0 1 1 1 0 Prim-pol family 5 PPP4R2 PF09184.11 KXX82240.1 - 0.44 10.1 15.4 0.95 9.0 15.4 1.5 1 0 0 1 1 1 0 PPP4R2 NPR3 PF03666.13 KXX82240.1 - 0.95 8.2 14.2 1.6 7.4 14.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 KXX82240.1 - 1.8 7.3 9.4 2.8 6.6 9.4 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 KXX82240.1 - 2.3 7.1 8.0 4 6.3 8.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S64 PF08192.11 KXX82240.1 - 5.8 5.3 12.3 8.2 4.8 12.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 KXX82240.1 - 8 5.4 11.3 15 4.5 11.3 1.5 1 0 0 1 1 1 0 Solute carrier family 12 CLTH PF10607.9 KXX82241.1 - 8.2e-31 106.9 0.0 1.5e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KXX82241.1 - 1.1e-05 25.3 1.8 2e-05 24.5 1.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KXX82241.1 - 0.011 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_2 PF13639.6 KXX82241.1 - 0.013 15.8 2.0 0.021 15.2 2.0 1.3 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KXX82241.1 - 0.021 14.7 1.3 0.037 13.9 1.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Flagellin_C PF00700.21 KXX82241.1 - 0.03 14.7 0.1 0.063 13.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region zf-C3HC4_3 PF13920.6 KXX82241.1 - 0.058 13.3 1.3 0.098 12.5 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXX82241.1 - 0.07 13.1 1.6 0.11 12.4 1.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXX82241.1 - 0.1 12.8 2.7 0.19 11.9 2.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXX82241.1 - 0.31 10.9 3.8 0.55 10.1 3.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX82241.1 - 0.43 10.5 2.9 0.76 9.7 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HlyIII PF03006.20 KXX82242.1 - 2.2e-63 214.0 17.9 2.8e-63 213.7 17.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related An_peroxidase PF03098.15 KXX82242.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase PG_binding_1 PF01471.18 KXX82243.1 - 0.00021 21.5 0.0 0.12 12.6 0.0 3.4 3 0 0 3 3 3 1 Putative peptidoglycan binding domain BLOC1_2 PF10046.9 KXX82243.1 - 0.048 14.0 2.2 0.15 12.4 2.2 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KXX82243.1 - 0.94 10.1 4.1 28 5.4 1.0 2.9 2 0 0 2 2 2 0 SlyX Tropomyosin_1 PF12718.7 KXX82243.1 - 1.3 9.2 10.0 0.034 14.3 1.4 2.5 3 0 0 3 3 3 0 Tropomyosin like AIM5 PF17050.5 KXX82243.1 - 1.8 9.4 5.2 11 7.0 0.1 3.3 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 Spc7 PF08317.11 KXX82243.1 - 1.9 7.3 11.0 0.028 13.3 3.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 KXX82243.1 - 3.7 6.1 4.3 1.8 7.1 1.9 1.6 2 0 0 2 2 2 0 AAA domain HMMR_N PF15905.5 KXX82243.1 - 8.7 5.7 8.2 0.43 10.0 2.2 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Ank_2 PF12796.7 KXX82245.1 - 9.3e-78 256.9 3.0 2.2e-14 53.8 0.0 7.5 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX82245.1 - 2.6e-66 219.2 6.5 8e-09 35.9 0.1 9.0 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KXX82245.1 - 3.4e-65 213.8 10.3 7.8e-06 26.1 0.0 13.7 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 KXX82245.1 - 3.8e-64 205.0 3.2 9.7e-06 25.6 0.0 13.7 13 0 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.6 KXX82245.1 - 3.3e-53 177.1 18.4 8.3e-06 26.0 0.1 12.1 2 2 11 13 13 13 11 Ankyrin repeats (many copies) Peptidase_S8 PF00082.22 KXX82245.1 - 1.3e-13 50.9 0.6 1.8e-12 47.2 0.6 2.4 1 1 0 1 1 1 1 Subtilase family Polyoma_agno PF01736.16 KXX82245.1 - 0.029 14.1 0.0 2.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Polyomavirus agnoprotein DUF2789 PF10982.8 KXX82245.1 - 0.069 13.3 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) HET PF06985.11 KXX82246.1 - 5.9e-29 101.3 0.0 1.2e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KXX82247.1 - 1.3e-69 234.5 0.0 2.6e-69 233.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX82247.1 - 1.5e-49 168.6 0.0 2.6e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KXX82247.1 - 5.5e-27 94.0 0.0 1.1e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KXX82247.1 - 6.6e-18 64.6 0.5 2.6e-17 62.7 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXX82247.1 - 3e-16 59.6 0.1 5.9e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXX82247.1 - 1e-13 51.7 0.1 2.3e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KXX82247.1 - 1.7e-07 30.9 0.0 9.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 KXX82247.1 - 0.016 15.1 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KXX82247.1 - 0.027 13.3 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase SAM_PNT PF02198.16 KXX82247.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain LRR_6 PF13516.6 KXX82248.1 - 0.061 13.4 5.0 20 5.5 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 KXX82248.1 - 0.47 11.2 8.4 13 6.8 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich Repeat DUF3774 PF12609.8 KXX82248.1 - 1.6 9.8 4.2 0.74 10.9 0.4 2.4 2 0 0 2 2 2 0 Wound-induced protein PPP4R2 PF09184.11 KXX82250.1 - 1.6e-06 27.9 0.1 1.6e-06 27.9 0.1 2.8 2 1 1 3 3 3 1 PPP4R2 EPL1 PF10513.9 KXX82250.1 - 0.003 18.0 7.0 0.4 11.0 0.7 2.2 2 0 0 2 2 2 2 Enhancer of polycomb-like Apc15p PF05841.11 KXX82250.1 - 0.014 16.2 4.6 0.014 16.2 4.6 2.6 2 0 0 2 2 2 0 Apc15p protein Spt20 PF12090.8 KXX82250.1 - 0.015 14.9 16.7 0.015 14.9 16.7 2.5 2 0 0 2 2 2 0 Spt20 family Neur_chan_memb PF02932.16 KXX82250.1 - 0.097 12.7 2.4 0.5 10.4 0.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 KXX82250.1 - 0.25 11.3 32.7 0.46 10.4 20.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phostensin_N PF13916.6 KXX82250.1 - 0.4 11.0 8.2 0.53 10.7 4.7 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Ndc1_Nup PF09531.10 KXX82250.1 - 0.77 8.4 13.2 1.7 7.3 5.5 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Menin PF05053.13 KXX82250.1 - 0.94 7.8 12.1 0.19 10.1 2.1 2.0 2 0 0 2 2 2 0 Menin DUF3391 PF11871.8 KXX82250.1 - 2.9 8.4 9.1 12 6.4 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Suf PF05843.14 KXX82250.1 - 4.6 7.1 21.1 1.1 9.2 4.6 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 KXX82250.1 - 6.1 6.8 11.9 0.56 10.2 4.3 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Band_3_cyto PF07565.13 KXX82250.1 - 6.3 6.5 6.8 2.1 8.1 1.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2722 PF10846.8 KXX82250.1 - 8.2 5.2 24.7 2.6 6.9 16.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF1772 PF08592.11 KXX82251.1 - 0.0024 18.2 9.5 0.0079 16.5 0.3 3.3 2 2 0 3 3 3 2 Domain of unknown function (DUF1772) CRPA PF05745.11 KXX82251.1 - 0.11 12.5 6.1 0.66 10.0 0.2 3.2 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Ribophorin_II PF05817.14 KXX82252.1 - 1.3e-33 116.5 0.2 2.3e-33 115.7 0.2 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PufQ PF05398.11 KXX82252.1 - 0.11 12.6 1.1 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 PufQ cytochrome subunit Carn_acyltransf PF00755.20 KXX82253.1 - 0.12 11.0 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase Cep57_MT_bd PF06657.13 KXX82255.1 - 1.3e-22 80.0 0.5 1.3e-22 80.0 0.5 7.9 6 1 1 7 7 7 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KXX82255.1 - 2.1e-13 50.1 8.9 2.1e-13 50.1 8.9 8.0 5 4 2 7 7 7 3 Centrosome localisation domain of PPC89 ADIP PF11559.8 KXX82255.1 - 0.00038 20.6 7.8 0.00038 20.6 7.8 7.5 6 1 2 8 8 8 2 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KXX82255.1 - 0.018 15.5 3.3 0.018 15.5 3.3 9.3 7 1 2 9 9 9 0 Cell division protein ZapB HALZ PF02183.18 KXX82255.1 - 1.3 9.3 41.6 0.11 12.7 0.7 8.0 6 2 1 7 7 7 0 Homeobox associated leucine zipper Coat_F PF07875.12 KXX82255.1 - 1.8 8.9 5.3 3.1 8.1 1.0 3.2 3 0 0 3 3 3 0 Coat F domain Mst1_SARAH PF11629.8 KXX82255.1 - 3.6 7.7 8.3 10 6.3 0.0 3.9 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 DUF4710 PF15828.5 KXX82255.1 - 4.1 7.6 5.5 8.1 6.7 1.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Beta_elim_lyase PF01212.21 KXX82256.1 - 2.3e-71 240.5 0.0 2.9e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXX82256.1 - 5.2e-05 22.6 0.0 0.00053 19.3 0.0 1.9 1 1 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXX82256.1 - 0.013 14.1 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXX82256.1 - 0.13 11.5 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.18 KXX82257.1 - 4.1e-15 55.5 0.1 6.8e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82257.1 - 1.1e-05 25.5 11.0 1.1e-05 25.5 11.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fis1_TPR_N PF14852.6 KXX82257.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Bromodomain PF00439.25 KXX82258.1 - 5e-25 87.4 0.8 1e-24 86.4 0.8 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXX82258.1 - 3.8e-08 33.6 0.0 6.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXX82258.1 - 6.5e-07 29.3 0.3 1.7e-06 28.0 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXX82258.1 - 0.00028 21.2 0.3 0.00062 20.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Trehalase PF01204.18 KXX82259.1 - 1.8e-116 390.0 0.8 1.3e-115 387.2 0.8 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KXX82259.1 - 0.00063 18.8 0.1 0.0011 17.9 0.1 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase CDP-OH_P_transf PF01066.21 KXX82260.1 - 2.4e-16 60.3 0.1 2.4e-16 60.3 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M28 PF04389.17 KXX82261.1 - 1.3e-36 126.2 0.0 1.7e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Sulfate_transp PF00916.20 KXX82262.1 - 2.7e-103 345.7 22.3 3.5e-103 345.3 22.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXX82262.1 - 1.5e-08 34.3 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain zf-UBR PF02207.20 KXX82263.1 - 2.6e-19 69.1 16.0 6.6e-19 67.9 16.0 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KXX82263.1 - 0.0014 18.4 0.0 0.0039 16.9 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 KXX82263.1 - 0.019 15.3 0.2 0.019 15.3 0.2 4.1 4 1 1 5 5 5 0 Ring finger domain CAP_N PF01213.19 KXX82263.1 - 1 8.7 3.5 2.3 7.6 3.5 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RabGAP-TBC PF00566.18 KXX82264.1 - 3.4e-32 111.8 0.0 1.4e-26 93.5 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Methyltransf_25 PF13649.6 KXX82265.1 - 1.1e-11 45.3 0.1 3.4e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX82265.1 - 1.7e-09 38.3 0.0 2.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82265.1 - 1e-08 35.7 0.1 1.3e-07 32.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82265.1 - 4e-07 29.9 0.0 5.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX82265.1 - 6.1e-06 25.7 0.0 2.1e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KXX82265.1 - 0.03 13.2 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 KXX82265.1 - 0.083 12.4 0.0 0.49 9.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXX82265.1 - 0.14 11.4 0.0 0.6 9.4 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase domain FmiP_Thoc5 PF09766.9 KXX82266.1 - 1.1e-34 120.3 12.8 1.4e-34 120.0 12.8 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 TSC22 PF01166.18 KXX82266.1 - 0.074 13.4 5.6 0.6 10.5 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.15 KXX82266.1 - 0.081 12.5 8.3 0.11 12.0 8.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 KXX82266.1 - 0.12 12.4 10.5 0.91 9.6 4.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3958 PF13125.6 KXX82266.1 - 0.13 12.5 11.4 2.2 8.5 9.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) DivIC PF04977.15 KXX82266.1 - 0.2 11.4 7.9 1.1 9.1 4.3 2.5 2 0 0 2 2 2 0 Septum formation initiator SPATA1_C PF15743.5 KXX82266.1 - 0.27 11.3 10.9 0.087 12.9 5.3 2.2 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus Cnn_1N PF07989.11 KXX82266.1 - 0.89 9.8 10.0 0.23 11.6 4.0 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF641 PF04859.12 KXX82266.1 - 1.4 9.2 9.1 2.3 8.6 0.3 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) YabA PF06156.13 KXX82266.1 - 2.5 8.8 9.0 14 6.4 0.4 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Casc1_N PF15927.5 KXX82266.1 - 3.6 7.2 14.9 0.12 12.1 7.9 2.0 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 N-terminus Lactonase PF10282.9 KXX82267.1 - 0.00019 20.8 0.0 0.0045 16.3 0.0 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller zf-H2C2_2 PF13465.6 KXX82268.1 - 1.5e-17 63.1 8.5 2.6e-06 27.6 0.3 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KXX82268.1 - 1.5e-14 53.5 11.5 1.2e-06 28.6 0.7 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX82268.1 - 3.6e-08 33.6 11.8 0.0013 19.4 0.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX82268.1 - 3.6e-05 23.9 1.5 0.4 11.0 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KXX82268.1 - 3.8e-05 24.2 2.4 3.5 8.3 0.1 3.1 1 1 2 3 3 3 3 FOXP coiled-coil domain zf-met PF12874.7 KXX82268.1 - 0.00014 22.1 1.5 0.025 15.0 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KXX82268.1 - 0.0031 18.2 5.2 0.07 13.8 0.8 2.2 1 1 1 2 2 2 2 TRAF-type zinc finger CHORD PF04968.12 KXX82268.1 - 0.03 15.0 7.2 0.15 12.8 2.0 2.6 1 1 1 2 2 2 0 CHORD zf-C2H2_8 PF15909.5 KXX82268.1 - 0.046 14.0 2.2 0.64 10.4 1.9 2.2 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KXX82268.1 - 0.06 13.5 3.2 3.2 7.8 0.1 2.9 1 1 2 3 3 3 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KXX82268.1 - 0.27 11.0 0.4 0.27 11.0 0.4 3.9 6 0 0 6 6 6 0 C2H2-type zinc-finger domain Prefoldin_2 PF01920.20 KXX82269.1 - 8.1e-25 86.8 3.1 1.1e-24 86.4 3.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit PI3K_P85_iSH2 PF16454.5 KXX82269.1 - 0.0036 16.9 3.0 0.0081 15.8 3.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Syntaxin-6_N PF09177.11 KXX82269.1 - 0.029 14.9 3.5 0.3 11.7 1.3 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal HAP1_N PF04849.13 KXX82269.1 - 0.092 11.9 0.2 0.092 11.9 0.2 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Seryl_tRNA_N PF02403.22 KXX82269.1 - 0.31 11.3 7.9 4.5 7.5 4.0 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Band_7 PF01145.25 KXX82270.1 - 3.6e-27 95.5 2.8 5.7e-27 94.9 2.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KXX82270.1 - 0.038 13.7 0.3 0.06 13.0 0.3 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family DEAD PF00270.29 KXX82271.1 - 5.8e-36 123.9 0.0 1.6e-35 122.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX82271.1 - 7.4e-23 81.0 0.0 1.7e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXX82271.1 - 1.3e-20 73.4 0.1 2.2e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXX82271.1 - 0.0013 18.8 0.0 0.0057 16.7 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXX82271.1 - 0.0028 16.9 2.8 0.038 13.2 0.0 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase IHABP4_N PF16174.5 KXX82271.1 - 1.7 9.2 21.0 3.1 8.4 21.0 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Hydrolase_4 PF12146.8 KXX82272.1 - 1.1e-14 54.3 0.5 1.3e-14 54.0 0.5 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX82272.1 - 1.2e-14 54.6 0.2 1.4e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX82272.1 - 4.5e-14 53.6 2.1 7.3e-14 52.9 2.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXX82272.1 - 0.00099 18.6 0.3 0.0013 18.2 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KXX82272.1 - 0.0034 17.5 0.1 0.005 17.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KXX82272.1 - 0.0035 17.1 0.1 0.0083 15.9 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.25 KXX82272.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 KXX82272.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 KXX82272.1 - 0.062 12.8 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) AXE1 PF05448.12 KXX82272.1 - 0.15 10.7 1.8 2 7.0 0.1 2.0 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Skp1_POZ PF03931.15 KXX82274.1 - 1.7e-11 44.1 0.0 2.3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.13 KXX82275.1 - 5e-47 159.8 0.0 8.5e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KXX82275.1 - 3.1e-07 31.1 0.5 6e-07 30.2 0.4 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DASH_Dad1 PF08649.10 KXX82276.1 - 6.6e-27 93.5 2.8 8.7e-27 93.1 2.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KXX82276.1 - 0.055 13.4 0.3 0.073 13.1 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 CK2S PF15011.6 KXX82276.1 - 0.059 13.3 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate V_ATPase_I PF01496.19 KXX82276.1 - 0.14 10.0 1.9 0.14 10.1 1.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ras PF00071.22 KXX82277.1 - 1.1e-47 161.7 0.0 1.4e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX82277.1 - 4.5e-20 72.0 0.0 8e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX82277.1 - 2.5e-05 23.8 0.0 5e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KXX82277.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ima1_N PF09779.9 KXX82278.1 - 9.9e-35 120.3 1.1 1.6e-34 119.7 1.1 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 KXX82278.1 - 0.15 12.1 5.8 0.19 11.8 0.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KXX82278.1 - 2.2 8.3 5.8 0.92 9.5 0.9 2.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 KXX82278.1 - 4.1 7.4 6.6 1 9.4 3.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RNHCP PF12647.7 KXX82278.1 - 6.8 6.7 5.7 3.8 7.5 0.1 2.6 3 0 0 3 3 3 0 RNHCP domain Sec6 PF06046.13 KXX82279.1 - 2.2e-169 564.5 11.4 3.2e-169 564.0 11.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KXX82279.1 - 5.1e-05 22.4 1.9 0.00016 20.8 1.9 1.8 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KXX82279.1 - 0.049 12.9 2.4 0.086 12.1 1.2 2.0 1 1 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex TSP_NTD PF17804.1 KXX82279.1 - 0.24 11.7 2.9 0.33 11.2 0.1 2.7 2 1 0 2 2 2 0 Tail specific protease N-terminal domain THOC7 PF05615.13 KXX82279.1 - 7.6 6.8 10.7 7 6.9 0.1 3.6 3 1 0 3 3 3 0 Tho complex subunit 7 COX7C PF02935.16 KXX82281.1 - 1.7e-22 79.4 1.8 2e-22 79.2 1.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Tcf25 PF04910.14 KXX82282.1 - 6.6e-58 196.4 2.9 9.1e-58 196.0 2.9 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PGA2 PF07543.12 KXX82282.1 - 0.26 11.3 9.0 0.76 9.8 9.0 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 Vpu PF00558.19 KXX82282.1 - 0.95 9.3 6.7 5.1 6.9 1.2 2.7 2 0 0 2 2 2 0 Vpu protein Pox_Ag35 PF03286.14 KXX82282.1 - 9.1 6.0 13.4 25 4.6 11.7 2.4 2 1 0 2 2 2 0 Pox virus Ag35 surface protein MRP-S25 PF13741.6 KXX82283.1 - 5.6e-23 81.7 0.7 6.4e-23 81.5 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 P22_Cro PF14549.6 KXX82283.1 - 0.066 13.1 0.2 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro DUF2934 PF11154.8 KXX82283.1 - 0.29 10.8 0.3 0.29 10.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2934) Alg14 PF08660.11 KXX82284.1 - 2e-49 167.9 0.0 2.7e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PEN-2 PF10251.9 KXX82284.1 - 0.043 14.2 0.2 0.14 12.5 0.2 1.9 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Steroid_dh PF02544.16 KXX82285.1 - 1.2e-21 77.3 0.1 1.2e-21 77.3 0.1 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KXX82285.1 - 0.0017 18.7 0.5 0.0067 16.8 0.5 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KXX82285.1 - 0.002 17.7 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GCN5L1 PF06320.13 KXX82286.1 - 1.7e-15 57.2 0.8 2.7e-15 56.5 0.8 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) PRCC PF10253.9 KXX82286.1 - 0.0062 17.3 6.7 0.0062 17.3 6.7 1.5 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting TFIIA PF03153.13 KXX82286.1 - 0.0085 16.1 1.5 0.01 15.9 1.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Serglycin PF04360.12 KXX82286.1 - 0.027 14.4 7.6 0.027 14.4 7.6 2.5 3 1 1 4 4 4 0 Serglycin BLOC1_2 PF10046.9 KXX82286.1 - 0.13 12.6 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_10 PF12846.7 KXX82286.1 - 0.18 10.7 0.2 0.3 9.9 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain SOG2 PF10428.9 KXX82287.1 - 5.7e-72 243.6 0.9 6e-46 157.7 0.0 4.1 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 KXX82287.1 - 5.6e-17 61.3 1.5 8.5e-10 38.3 0.8 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXX82287.1 - 3.2e-12 46.5 5.1 6.9e-06 26.3 1.2 4.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXX82287.1 - 0.24 12.1 8.7 8.8 7.3 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat PHA_synth_III_E PF09712.10 KXX82287.1 - 0.26 10.3 0.5 0.57 9.2 0.5 1.5 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) LRR_6 PF13516.6 KXX82287.1 - 0.51 10.5 4.8 40 4.6 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Helicase_C PF00271.31 KXX82288.1 - 3.5e-17 62.7 0.0 7.1e-15 55.3 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KXX82288.1 - 8.7e-16 58.2 0.0 1.5e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KXX82288.1 - 1.8e-12 47.8 3.9 4e-12 46.7 3.9 1.6 1 0 0 1 1 1 1 RecQ zinc-binding DUF2407_C PF13373.6 KXX82289.1 - 2.2e-35 121.9 0.0 3.1e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KXX82289.1 - 1.2e-28 99.8 0.0 1.8e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TrbC PF04956.13 KXX82289.1 - 0.014 15.6 1.3 0.023 14.9 1.3 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family rRNA_proc-arch PF13234.6 KXX82290.1 - 2e-89 300.1 0.1 9.2e-89 297.9 0.0 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KXX82290.1 - 2.2e-47 160.8 4.0 2.6e-47 160.5 2.7 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KXX82290.1 - 7.7e-18 64.9 0.1 3.7e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX82290.1 - 1.9e-07 31.4 0.7 1.4e-06 28.6 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX82290.1 - 1.3e-05 25.3 0.0 6.4e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KXX82290.1 - 0.0084 15.2 0.0 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Prp19 PF08606.11 KXX82290.1 - 0.05 13.6 0.5 5.8 7.0 0.1 2.6 2 0 0 2 2 2 0 Prp19/Pso4-like ATPase PF06745.13 KXX82290.1 - 0.085 12.2 0.1 2.9 7.2 0.0 3.0 4 0 0 4 4 4 0 KaiC AAA_22 PF13401.6 KXX82290.1 - 0.12 12.7 0.0 0.78 10.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain DFP PF04127.15 KXX82290.1 - 0.13 12.1 0.3 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DDE_1 PF03184.19 KXX82291.1 - 1.1e-26 93.6 0.0 3.9e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.16 KXX82291.1 - 1.4e-07 31.1 0.0 3.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 KXX82291.1 - 1e-06 28.7 0.1 2.5e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KXX82291.1 - 0.01 15.6 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_28 PF13518.6 KXX82291.1 - 0.07 13.3 0.1 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 KXX82291.1 - 0.11 12.4 0.4 3.9 7.4 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain HET PF06985.11 KXX82292.1 - 5.7e-34 117.6 0.1 8.8e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ydc2-catalyt PF09159.10 KXX82293.1 - 1.1e-58 199.2 0.0 1.3e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 KXX82293.1 - 4.2e-05 23.2 0.2 9.9e-05 22.0 0.2 1.6 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.13 KXX82293.1 - 0.078 13.1 0.0 43 4.2 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A22 protein Pyr_redox_2 PF07992.14 KXX82294.1 - 1.6e-64 218.0 2.1 2.1e-64 217.6 2.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXX82294.1 - 6.9e-32 110.0 0.4 1.7e-31 108.7 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXX82294.1 - 2e-19 69.9 3.2 9.6e-18 64.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXX82294.1 - 7.1e-17 61.6 0.2 9.8e-17 61.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXX82294.1 - 6.5e-05 22.2 0.1 0.00055 19.2 0.0 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KXX82294.1 - 0.00037 20.0 0.2 0.00057 19.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX82294.1 - 0.00082 18.2 5.1 0.6 8.7 1.7 3.1 2 1 1 3 3 3 2 HI0933-like protein GIDA PF01134.22 KXX82294.1 - 0.002 17.3 0.6 0.0089 15.2 0.2 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 KXX82294.1 - 0.01 15.1 0.8 0.021 14.1 0.8 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KXX82294.1 - 0.013 15.1 3.2 0.29 10.7 1.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX82294.1 - 0.035 13.2 5.5 1 8.4 2.4 2.5 2 0 0 2 2 2 0 FAD binding domain Ntox47 PF15540.6 KXX82294.1 - 0.094 13.0 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Bacterial toxin 47 NAD_binding_8 PF13450.6 KXX82294.1 - 0.17 12.1 3.4 0.23 11.7 2.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KXX82294.1 - 0.39 10.6 0.0 0.39 10.6 0.0 2.9 4 0 0 4 4 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RasGEF PF00617.19 KXX82295.1 - 9.4e-48 162.7 0.1 1.6e-47 162.0 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXX82295.1 - 3.8e-14 52.8 0.3 8.4e-14 51.7 0.3 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF2244 PF10003.9 KXX82296.1 - 0.11 12.1 0.3 0.27 10.9 0.3 1.6 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF3984 PF13136.6 KXX82296.1 - 0.93 8.8 7.3 0.28 10.5 4.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) zf-HIT PF04438.16 KXX82297.1 - 3.3e-09 36.4 7.8 6.1e-09 35.6 7.8 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KXX82297.1 - 1.8 8.7 10.4 4.9 7.3 10.4 1.7 1 0 0 1 1 1 0 MYND finger DENN PF02141.21 KXX82298.1 - 5.1e-40 137.4 0.0 9.1e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KXX82298.1 - 6.8e-07 29.9 0.6 3.3e-06 27.7 0.0 2.5 3 0 0 3 3 3 1 uDENN domain Elongin_A PF06881.11 KXX82298.1 - 0.0087 16.6 4.9 0.04 14.4 4.9 2.1 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Dfp1_Him1_M PF08630.10 KXX82298.1 - 0.072 13.3 1.4 5.2 7.3 2.3 2.4 2 0 0 2 2 2 0 Dfp1/Him1, central region DUF3135 PF11333.8 KXX82298.1 - 0.3 11.3 3.7 1.9 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Met_10 PF02475.16 KXX82299.1 - 3.7e-07 30.1 0.0 7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF2470 PF10615.9 KXX82300.1 - 1.6e-22 79.9 0.0 2.4e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Porph_ging PF09697.10 KXX82301.1 - 0.096 13.2 2.7 1.3 9.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (Porph_ging) EF-hand_7 PF13499.6 KXX82302.1 - 1.2e-08 35.3 1.1 1.2e-08 35.3 1.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXX82302.1 - 1.9e-08 33.6 0.5 0.00083 19.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXX82302.1 - 4.5e-07 29.0 1.3 3.2e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXX82302.1 - 2.9e-06 26.5 0.8 1.5e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXX82302.1 - 0.0019 18.0 1.7 0.0035 17.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair Pirin PF02678.16 KXX82303.1 - 9.4e-31 106.0 0.0 6.8e-30 103.2 0.0 2.2 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KXX82303.1 - 1.3e-26 93.0 0.1 7.2e-26 90.6 0.1 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KXX82303.1 - 5e-10 39.0 2.2 9.6e-06 25.2 0.3 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXX82303.1 - 7.2e-05 22.4 1.2 0.22 11.2 0.4 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF861) Perilipin PF03036.16 KXX82304.1 - 0.00096 18.3 0.8 0.034 13.2 0.0 2.0 1 1 0 2 2 2 2 Perilipin family PET10 PF17316.2 KXX82304.1 - 0.0013 18.4 0.1 0.0038 16.8 0.0 1.8 1 1 0 2 2 2 1 Petite colonies protein 10 Fungal_trans PF04082.18 KXX82305.1 - 2.8e-13 49.5 0.4 4.6e-13 48.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82305.1 - 1.2e-07 31.8 7.4 2.3e-07 30.8 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.14 KXX82306.1 - 2.4e-27 96.1 0.7 1.9e-26 93.1 0.7 1.9 1 1 0 1 1 1 1 Phosphoesterase family Ras PF00071.22 KXX82307.1 - 4.5e-16 58.9 0.0 1.1e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXX82307.1 - 4.5e-09 36.6 0.0 6.1e-08 32.9 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXX82307.1 - 6.9e-05 22.4 0.0 0.00021 20.8 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit TsaE PF02367.17 KXX82307.1 - 0.0015 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KXX82307.1 - 0.0023 17.9 0.6 0.0068 16.3 0.0 2.0 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 KXX82307.1 - 0.0023 18.0 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXX82307.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 KXX82307.1 - 0.0078 15.3 0.3 0.035 13.2 0.3 1.8 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ATP-synt_ab PF00006.25 KXX82307.1 - 0.0091 15.7 0.6 0.041 13.5 0.0 2.2 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 KXX82307.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 KXX82307.1 - 0.02 14.4 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KXX82307.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 KXX82307.1 - 0.021 14.6 0.1 0.045 13.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXX82307.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KXX82307.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXX82307.1 - 0.044 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KXX82307.1 - 0.054 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.16 KXX82307.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 KXX82307.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXX82307.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KXX82307.1 - 0.12 12.5 0.0 2.3 8.2 0.1 2.1 1 1 1 2 2 2 0 Dynamin family RNA_helicase PF00910.22 KXX82307.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 KXX82307.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arf PF00025.21 KXX82307.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family G-alpha PF00503.20 KXX82307.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 KXX82307.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA PF00004.29 KXX82308.1 - 2.8e-54 183.1 0.0 1.8e-38 132.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX82308.1 - 4.9e-11 43.1 0.1 0.00033 20.9 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KXX82308.1 - 2.8e-10 40.9 0.0 0.00026 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 KXX82308.1 - 2.8e-09 36.6 0.2 6.1e-08 32.3 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KXX82308.1 - 3.1e-09 37.0 0.1 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KXX82308.1 - 6.6e-09 35.4 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KXX82308.1 - 1e-08 34.8 0.0 0.001 18.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 KXX82308.1 - 1.4e-08 34.6 0.1 0.0031 17.3 0.0 3.5 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXX82308.1 - 2.6e-07 30.2 0.2 0.005 16.2 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXX82308.1 - 3e-07 31.1 0.0 0.039 14.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 KXX82308.1 - 6.1e-07 29.5 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KXX82308.1 - 6.8e-07 29.6 0.0 0.00019 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXX82308.1 - 1.3e-06 28.6 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXX82308.1 - 1.3e-06 28.2 0.0 0.026 14.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXX82308.1 - 5.3e-06 26.8 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 KXX82308.1 - 7.9e-06 26.4 0.0 0.045 14.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter AAA_19 PF13245.6 KXX82308.1 - 1.8e-05 25.1 0.1 0.43 10.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KXX82308.1 - 2.3e-05 24.4 1.8 0.024 14.5 0.0 3.4 4 0 0 4 4 3 1 NACHT domain AAA_7 PF12775.7 KXX82308.1 - 2.5e-05 23.9 0.2 0.058 12.9 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 KXX82308.1 - 3.3e-05 23.2 0.0 0.084 12.0 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain IstB_IS21 PF01695.17 KXX82308.1 - 4.6e-05 23.2 0.0 0.37 10.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 KXX82308.1 - 5e-05 23.3 0.0 0.45 10.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KXX82308.1 - 5e-05 23.2 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KXX82308.1 - 5.3e-05 22.7 0.1 0.026 13.9 0.2 2.5 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 KXX82308.1 - 8.8e-05 22.3 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 KXX82308.1 - 0.00011 21.9 0.2 0.27 10.8 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KXX82308.1 - 0.00015 21.5 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXX82308.1 - 0.00017 21.9 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KXX82308.1 - 0.00032 20.7 0.2 6.3 6.6 0.0 4.0 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KXX82308.1 - 0.00065 19.2 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 KXX82308.1 - 0.0012 18.7 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KXX82308.1 - 0.0024 18.3 0.1 0.75 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KXX82308.1 - 0.0032 16.6 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 TniB PF05621.11 KXX82308.1 - 0.0043 16.5 0.2 6.9 6.0 0.1 3.5 3 1 0 3 3 3 0 Bacterial TniB protein DUF2075 PF09848.9 KXX82308.1 - 0.0049 16.2 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KXX82308.1 - 0.014 15.4 0.0 4.8 7.2 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 KXX82308.1 - 0.015 15.0 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXX82308.1 - 0.015 14.5 0.0 0.42 9.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 KXX82308.1 - 0.019 14.9 0.0 11 5.9 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain KTI12 PF08433.10 KXX82308.1 - 0.038 13.5 0.0 7.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CPT PF07931.12 KXX82308.1 - 0.05 13.4 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.6 KXX82308.1 - 0.055 13.6 0.0 8.6 6.5 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KXX82308.1 - 0.068 13.1 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 NTPase cobW PF02492.19 KXX82308.1 - 0.068 12.7 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.22 KXX82308.1 - 0.076 13.1 0.1 14 5.8 0.0 2.8 3 0 0 3 3 3 0 Shikimate kinase T2SSE PF00437.20 KXX82308.1 - 0.087 11.9 0.0 8.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Hydin_ADK PF17213.3 KXX82308.1 - 0.11 12.8 0.2 0.91 9.8 0.1 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain HATPase_c PF02518.26 KXX82308.1 - 0.11 13.0 0.0 22 5.6 0.0 2.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cir_N PF10197.9 KXX82309.1 - 1.7e-07 31.3 1.3 1.7e-07 31.3 1.3 2.6 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CAP_N PF01213.19 KXX82311.1 - 1 8.8 10.7 1.6 8.1 10.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KXX82311.1 - 2 8.4 6.8 3.6 7.6 6.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator KxDL PF10241.9 KXX82312.1 - 1.4e-31 108.6 1.8 2e-31 108.1 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 KXX82312.1 - 0.085 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Activator of aromatic catabolism zf-met2 PF12907.7 KXX82312.1 - 5 7.3 5.2 7.3 6.8 0.6 2.2 2 0 0 2 2 2 0 Zinc-binding Aminotran_1_2 PF00155.21 KXX82313.1 - 4.2e-63 213.7 0.0 4.9e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXX82313.1 - 0.00067 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXX82313.1 - 0.0011 18.4 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXX82313.1 - 0.0011 17.6 0.0 0.0019 16.8 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXX82313.1 - 0.014 14.4 0.0 0.029 13.3 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V CcmH PF03918.14 KXX82314.1 - 0.097 12.0 0.8 0.43 9.9 0.2 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein LSM14 PF12701.7 KXX82315.1 - 1.4e-31 108.4 0.0 1.7e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KXX82315.1 - 5.6e-07 29.6 0.0 6.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KXX82315.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 LSM domain FDF PF09532.10 KXX82316.1 - 5.9e-22 78.5 1.8 5.9e-22 78.5 1.8 2.7 3 0 0 3 3 3 1 FDF domain TFIIA PF03153.13 KXX82316.1 - 1.3 8.9 14.0 1.7 8.5 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.18 KXX82318.1 - 3.9e-10 39.2 0.1 8.4e-10 38.1 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Choline_kinase PF01633.20 KXX82319.1 - 2e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KXX82319.1 - 0.011 15.6 0.2 0.056 13.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family HMA PF00403.26 KXX82320.1 - 6.5e-16 58.5 0.3 9.1e-16 58.1 0.3 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 KXX82320.1 - 0.063 13.6 0.2 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Clr5 PF14420.6 KXX82321.1 - 7.3e-16 58.1 2.2 8.9e-16 57.9 0.8 2.0 2 0 0 2 2 2 1 Clr5 domain GSH-S_N PF02951.14 KXX82321.1 - 0.025 14.7 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain CREPT PF16566.5 KXX82321.1 - 1.6 8.9 3.5 2.9 8.0 0.1 2.9 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour Rogdi_lz PF10259.9 KXX82322.1 - 2.9e-85 286.0 0.0 6e-53 180.0 0.2 2.0 1 1 1 2 2 2 2 Rogdi leucine zipper containing protein NIPSNAP PF07978.13 KXX82323.1 - 7.6e-41 138.5 0.7 1.3e-29 102.4 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP SR-25 PF10500.9 KXX82323.1 - 0.18 11.4 6.7 0.28 10.8 6.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_tran PF00005.27 KXX82324.1 - 4.4e-50 169.8 0.0 2.6e-27 96.0 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXX82324.1 - 4.1e-14 53.1 5.8 0.00055 19.8 0.8 4.8 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXX82324.1 - 1.4e-12 47.5 0.2 0.0022 17.5 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXX82324.1 - 1e-09 39.2 0.1 0.00011 22.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain Chromo PF00385.24 KXX82324.1 - 2e-07 30.8 0.1 4e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KXX82324.1 - 2e-07 31.1 0.0 0.0036 17.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXX82324.1 - 5.5e-07 29.2 0.7 0.0074 16.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXX82324.1 - 2e-06 27.8 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXX82324.1 - 0.00025 21.3 0.4 0.72 10.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXX82324.1 - 0.00025 21.3 0.0 0.0078 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXX82324.1 - 0.00034 20.4 0.1 0.15 11.7 0.2 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXX82324.1 - 0.00099 19.7 0.0 0.25 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXX82324.1 - 0.0021 18.2 0.0 1.1 9.6 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KXX82324.1 - 0.0029 17.8 0.0 3.1 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXX82324.1 - 0.0032 17.8 0.1 2.7 8.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase HEAT_2 PF13646.6 KXX82324.1 - 0.0036 17.7 3.2 5.8 7.4 0.0 4.4 3 1 1 4 4 4 0 HEAT repeats NACHT PF05729.12 KXX82324.1 - 0.004 17.1 0.2 1.7 8.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 KXX82324.1 - 0.0045 16.0 0.4 0.74 8.7 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KXX82324.1 - 0.0088 15.8 0.2 3.4 7.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KXX82324.1 - 0.0099 15.6 0.6 0.65 9.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXX82324.1 - 0.013 15.6 3.0 0.38 10.8 0.0 3.2 4 0 0 4 4 2 0 Helicase HerA, central domain AAA PF00004.29 KXX82324.1 - 0.017 15.6 0.0 6.4 7.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KXX82324.1 - 0.018 15.1 0.0 1.4 8.9 0.0 2.8 2 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 KXX82324.1 - 0.019 15.4 0.1 1.8 8.9 0.0 3.1 3 0 0 3 3 2 0 AAA ATPase domain PduV-EutP PF10662.9 KXX82324.1 - 0.021 14.5 0.0 0.99 9.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 KXX82324.1 - 0.022 13.5 0.0 2.3 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KXX82324.1 - 0.03 13.9 0.1 7.9 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 KXX82324.1 - 0.037 11.6 0.7 3.3 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF815 PF05673.13 KXX82324.1 - 0.12 11.5 0.1 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KXX82324.1 - 0.12 11.5 0.0 10 5.2 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KXX82324.1 - 0.13 12.2 0.3 15 5.5 0.2 3.0 3 0 0 3 3 2 0 NTPase AAA_14 PF13173.6 KXX82324.1 - 0.17 11.9 0.0 11 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXX82324.1 - 0.2 11.7 0.4 38 4.3 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RRM_1 PF00076.22 KXX82325.1 - 4.5e-14 52.0 0.0 7.6e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXX82325.1 - 3.2e-05 23.5 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXX82325.1 - 0.077 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Glyco_hydro_16 PF00722.21 KXX82326.1 - 7.7e-15 54.8 0.0 2.8e-14 53.0 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 KXX82327.1 - 3.1e-51 174.1 2.2 3.1e-51 174.1 2.2 2.5 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXX82327.1 - 8.4e-05 22.4 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXX82327.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2076 PF09849.9 KXX82328.1 - 0.12 12.4 1.4 0.12 12.4 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Rpp20 PF12328.8 KXX82329.1 - 1.1e-26 93.4 1.0 1.3e-26 93.1 1.0 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KXX82329.1 - 1.1e-09 38.0 0.0 3.4e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Alba EBP50_C PF09007.11 KXX82330.1 - 0.47 11.4 6.2 0.071 14.1 1.1 1.9 1 1 1 2 2 2 0 EBP50, C-terminal Pkinase PF00069.25 KXX82331.1 - 2.2e-25 89.5 0.0 2.4e-24 86.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX82331.1 - 6.9e-12 45.2 0.0 0.00016 21.1 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXX82331.1 - 0.0024 17.8 0.1 0.0068 16.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXX82331.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kri1_C PF12936.7 KXX82331.1 - 0.044 14.0 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 KRI1-like family C-terminal Kinase-like PF14531.6 KXX82331.1 - 0.045 13.1 0.0 12 5.1 0.0 2.6 3 0 0 3 3 3 0 Kinase-like Abhydrolase_6 PF12697.7 KXX82332.1 - 0.00079 20.1 3.1 0.0015 19.2 3.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Arginase PF00491.21 KXX82333.1 - 8.6e-81 271.5 0.1 1.1e-80 271.1 0.1 1.0 1 0 0 1 1 1 1 Arginase family FtsJ PF01728.19 KXX82333.1 - 0.083 13.0 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 FtsJ-like methyltransferase UPF0489 PF12640.7 KXX82333.1 - 0.12 12.6 0.2 0.17 12.1 0.2 1.2 1 0 0 1 1 1 0 UPF0489 domain APH PF01636.23 KXX82334.1 - 2.8e-20 73.3 0.8 4.8e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3726 PF12525.8 KXX82334.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) Abhydrolase_6 PF12697.7 KXX82335.1 - 6.9e-11 43.2 12.5 1.3e-10 42.3 12.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX82335.1 - 1.4e-09 38.0 1.9 3.3e-09 36.8 1.9 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX82335.1 - 1.2e-08 34.6 1.1 3.4e-08 33.1 0.1 2.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 DUF4215 PF13948.6 KXX82336.1 - 3.7e-34 116.9 231.6 0.0023 18.3 1.4 20.2 10 5 9 19 19 19 18 Domain of unknown function (DUF4215) WD40 PF00400.32 KXX82337.1 - 7.5e-20 70.9 2.7 0.0014 19.4 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX82337.1 - 1.3e-09 38.2 0.0 0.3 11.4 0.0 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX82337.1 - 0.0013 17.7 0.6 0.71 8.8 0.0 3.4 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXX82337.1 - 0.016 14.5 0.2 2.7 7.2 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KXX82337.1 - 0.14 10.5 0.0 3.2 5.9 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz KNOX1 PF03790.13 KXX82337.1 - 0.19 11.5 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 KNOX1 domain GDC-P PF02347.16 KXX82338.1 - 1.8e-174 580.6 0.0 4.5e-160 533.2 0.0 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KXX82338.1 - 1.4e-05 24.5 0.1 3.5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXX82338.1 - 0.069 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family UvrD_C_2 PF13538.6 KXX82338.1 - 0.19 11.6 0.2 0.43 10.5 0.2 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Nup54 PF13874.6 KXX82339.1 - 8.3e-40 136.1 0.3 8.3e-40 136.1 0.3 2.9 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KXX82339.1 - 3e-15 55.5 10.5 3e-15 55.5 10.5 1.9 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain Adhesin_P1_N PF18652.1 KXX82339.1 - 0.0023 17.9 2.5 0.0023 17.9 2.5 2.1 2 0 0 2 2 1 1 Adhesin P1 N-terminal domain V-SNARE_C PF12352.8 KXX82339.1 - 0.009 16.3 1.5 0.83 10.0 0.1 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GAPES3 PF17154.4 KXX82339.1 - 0.14 12.1 2.3 5.9 6.9 0.1 3.3 3 1 1 4 4 4 0 Gammaproteobacterial periplasmic sensor domain FapA PF03961.13 KXX82339.1 - 0.44 9.1 1.8 0.64 8.6 1.6 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A EzrA PF06160.12 KXX82339.1 - 0.51 8.4 6.3 3.5 5.7 0.9 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CCDC-167 PF15188.6 KXX82339.1 - 1.1 9.7 5.2 1.5 9.3 1.7 2.6 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 DivIVA PF05103.13 KXX82339.1 - 2.5 8.2 8.2 0.061 13.4 0.7 2.2 2 0 0 2 2 2 0 DivIVA protein HCMV_UL139 PF12507.8 KXX82339.1 - 8.8 6.7 7.7 46 4.4 0.1 3.1 2 1 1 3 3 3 0 Human Cytomegalovirus UL139 protein Spt20 PF12090.8 KXX82339.1 - 9.1 5.8 15.6 0.27 10.8 9.5 1.5 2 0 0 2 2 2 0 Spt20 family CHCH PF06747.13 KXX82340.1 - 3.2e-08 33.5 15.7 6.5e-07 29.3 5.6 2.5 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KXX82340.1 - 2.5e-07 30.6 9.1 3.9e-05 23.6 4.4 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KXX82340.1 - 4e-06 26.7 5.6 0.019 15.0 0.1 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CAP PF00188.26 KXX82341.1 - 6.3e-19 69.0 2.7 8.4e-19 68.6 2.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Fungal_trans PF04082.18 KXX82342.1 - 5.9e-07 28.8 0.0 4.5e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.20 KXX82343.1 - 2.1e-164 547.3 0.0 2.6e-164 547.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXX82343.1 - 1.2e-08 35.1 0.1 2.2e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXX82343.1 - 8.2e-06 26.2 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DUF1691 PF07950.11 KXX82344.1 - 9.8e-40 135.6 7.0 8.7e-34 116.5 4.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.8 KXX82345.1 - 8.1e-08 32.4 3.7 1.6e-07 31.4 3.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX82345.1 - 0.00011 22.4 0.9 0.00023 21.5 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXX82345.1 - 0.019 15.3 0.3 0.033 14.5 0.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KXX82345.1 - 0.072 13.6 0.8 0.13 12.7 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX82345.1 - 0.11 13.4 0.3 0.22 12.5 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Aminotran_4 PF01063.19 KXX82345.1 - 0.2 11.5 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Amino-transferase class IV zf-DBF PF07535.12 KXX82345.1 - 0.3 11.3 2.4 0.52 10.5 2.4 1.4 1 0 0 1 1 1 0 DBF zinc finger p450 PF00067.22 KXX82346.1 - 8.7e-48 163.2 0.0 1.2e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2268 PF10026.9 KXX82346.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Epimerase PF01370.21 KXX82347.1 - 2.8e-17 63.0 0.0 4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX82347.1 - 2e-11 43.9 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXX82347.1 - 1.5e-07 30.7 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXX82347.1 - 2.7e-05 23.5 0.0 8.8e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KXX82347.1 - 0.18 11.3 0.7 1.4 8.3 0.1 2.3 2 1 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.16 KXX82348.1 - 1e-32 113.5 26.2 1e-32 113.5 26.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4079 PF13301.6 KXX82348.1 - 0.47 10.6 0.0 0.47 10.6 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) SLATT_1 PF18181.1 KXX82348.1 - 0.98 9.4 2.8 6.6 6.7 0.5 2.8 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4231 PF14015.6 KXX82348.1 - 5.8 7.4 7.9 2.5 8.6 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Lipase_GDSL_2 PF13472.6 KXX82349.1 - 9.8e-14 52.1 0.1 1.3e-13 51.8 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ALGX PF16822.5 KXX82349.1 - 0.00017 21.4 0.0 0.087 12.5 0.0 2.1 2 0 0 2 2 2 2 SGNH hydrolase-like domain, acetyltransferase AlgX Lipase_GDSL PF00657.22 KXX82349.1 - 0.00052 20.0 0.0 0.0015 18.5 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4007 PF13182.6 KXX82353.1 - 0.16 11.1 0.2 4 6.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4007) AMP-binding PF00501.28 KXX82354.1 - 1.4e-65 221.6 0.0 1e-64 218.7 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX82354.1 - 1.1e-13 51.9 0.0 3.5e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_TAC_6 PF09550.10 KXX82354.1 - 0.054 13.9 1.1 7.6 7.1 0.0 2.8 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC adh_short_C2 PF13561.6 KXX82355.1 - 5.5e-61 206.1 0.1 6.3e-61 205.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX82355.1 - 9.5e-43 145.9 0.0 1.2e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX82355.1 - 3.1e-11 43.5 0.6 4.7e-11 42.9 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXX82355.1 - 5.2e-05 23.2 0.2 8.8e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXX82355.1 - 0.00059 20.5 0.0 0.0014 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX82355.1 - 0.0032 18.2 0.0 0.0069 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KXX82355.1 - 0.014 14.5 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ChuX_HutX PF06228.13 KXX82355.1 - 0.037 13.8 0.1 9.2 6.0 0.0 2.4 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX Epimerase PF01370.21 KXX82355.1 - 0.039 13.4 0.1 0.055 12.9 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RecC_C PF17946.1 KXX82355.1 - 0.041 13.7 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 RecC C-terminal domain Methyltransf_31 PF13847.6 KXX82355.1 - 0.046 13.5 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KXX82355.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Eno-Rase_NADH_b PF12242.8 KXX82355.1 - 0.068 12.9 1.2 6.6 6.6 0.2 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_11 PF08241.12 KXX82355.1 - 0.086 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.19 KXX82355.1 - 0.092 12.1 0.0 0.24 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_23 PF13489.6 KXX82355.1 - 0.11 12.3 0.0 0.56 10.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.24 KXX82356.1 - 2.9e-82 276.5 0.0 4.4e-82 275.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Citrate_synt PF00285.21 KXX82357.1 - 7.7e-101 337.7 0.0 9.1e-101 337.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Meth_synt_1 PF08267.12 KXX82357.1 - 0.073 12.6 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain ICL PF00463.21 KXX82358.1 - 6.9e-196 651.8 0.3 7.8e-196 651.6 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXX82358.1 - 2.3e-10 40.3 0.0 7.3e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4360 PF14273.6 KXX82360.1 - 5.6e-67 225.0 5.0 6.4e-67 224.9 5.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) EHN PF06441.12 KXX82361.1 - 5.7e-28 97.4 0.3 1.1e-27 96.5 0.3 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXX82361.1 - 5.4e-06 26.2 0.2 1.2e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Sugar_tr PF00083.24 KXX82362.1 - 1.2e-77 261.7 19.8 1.5e-77 261.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX82362.1 - 7.4e-17 61.3 26.1 7.4e-17 61.3 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FSH1 PF03959.13 KXX82364.1 - 4.5e-57 193.1 0.0 5.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXX82364.1 - 0.003 17.4 0.0 1.3 8.8 0.2 3.1 3 1 0 3 3 3 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXX82364.1 - 0.071 12.4 0.2 0.43 9.8 0.0 2.2 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DLIC PF05783.11 KXX82365.1 - 3.9e-33 115.0 0.2 2.3e-30 105.9 0.0 2.6 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.15 KXX82366.1 - 1e-60 204.4 0.0 1.6e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Sigma70_r4 PF04545.16 KXX82366.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_hydro_76 PF03663.14 KXX82366.1 - 0.35 10.3 2.5 0.3 10.5 0.7 1.8 2 1 0 2 2 2 0 Glycosyl hydrolase family 76 TRAM_LAG1_CLN8 PF03798.16 KXX82367.1 - 1.1e-39 136.2 16.2 1.8e-39 135.6 16.2 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KXX82367.1 - 3.7e-19 68.1 0.0 1.1e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 TRAM1-like protein RRM_1 PF00076.22 KXX82369.1 - 4e-16 58.6 0.0 4.9e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX82369.1 - 0.00075 19.6 0.0 0.0024 18.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif WD40 PF00400.32 KXX82370.1 - 3.8e-07 30.7 0.1 0.045 14.7 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX82370.1 - 0.00022 21.5 0.0 0.0068 16.7 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX82370.1 - 0.03 13.3 0.1 0.45 9.4 0.0 2.1 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXX82370.1 - 0.071 12.4 0.0 0.57 9.5 0.0 2.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KXX82370.1 - 0.11 12.2 0.5 29 4.3 0.0 3.0 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Septin PF00735.18 KXX82371.1 - 6e-108 360.4 0.1 1.2e-107 359.4 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXX82371.1 - 2.9e-06 27.3 0.0 6.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXX82371.1 - 0.00096 19.2 3.5 0.67 10.0 0.0 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KXX82371.1 - 0.0048 16.8 1.9 0.0063 16.4 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 KXX82371.1 - 0.013 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 KXX82371.1 - 0.048 13.8 0.5 0.091 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KXX82371.1 - 0.075 12.6 1.2 0.18 11.3 0.1 2.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KXX82371.1 - 0.077 12.3 0.2 0.19 11.0 0.2 1.7 1 1 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 KXX82371.1 - 0.11 12.7 1.3 0.27 11.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain EB1 PF03271.17 KXX82371.1 - 0.13 12.6 0.7 5.6 7.3 1.1 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif AAA_23 PF13476.6 KXX82371.1 - 8.8 6.8 8.3 20 5.6 3.6 2.2 2 1 0 2 2 2 0 AAA domain Bax1-I PF01027.20 KXX82372.1 - 6.2e-53 179.7 25.8 7.1e-53 179.5 25.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 TMEM171 PF15471.6 KXX82372.1 - 0.47 9.4 3.1 1.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 Spore_YhaL PF14147.6 KXX82372.1 - 1.6 8.5 3.9 0.73 9.6 0.1 2.4 3 0 0 3 3 3 0 Sporulation protein YhaL MFS_1 PF07690.16 KXX82375.1 - 1.6e-15 56.9 31.0 1.6e-15 56.9 31.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.9 KXX82377.1 - 5.5e-29 100.5 15.0 5.5e-29 100.5 15.0 3.4 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 GTP_EFTU PF00009.27 KXX82379.1 - 1.1e-35 123.0 3.8 4.3e-34 117.8 3.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXX82379.1 - 5.4e-27 94.0 0.1 1.7e-26 92.4 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KXX82379.1 - 1.7e-10 40.9 0.1 4.7e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 KXX82379.1 - 1.3e-09 37.8 0.0 3.4e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 KXX82379.1 - 8.9e-08 32.4 4.5 0.0042 17.4 0.3 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 Arf PF00025.21 KXX82379.1 - 2.7e-06 27.0 0.0 4.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 KXX82379.1 - 6e-06 25.9 0.2 1.1e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXX82379.1 - 9.7e-06 25.6 1.4 0.0023 17.9 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KXX82379.1 - 4.8e-05 23.1 0.3 0.00014 21.7 0.3 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KXX82379.1 - 0.00021 21.5 0.0 0.00045 20.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXX82379.1 - 0.00028 20.4 0.3 0.001 18.6 0.3 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 KXX82379.1 - 0.0063 15.5 1.0 0.015 14.3 0.4 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU_D4 PF14578.6 KXX82379.1 - 0.018 14.9 3.3 0.029 14.3 0.6 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 MMR_HSR1_Xtn PF16897.5 KXX82379.1 - 0.034 14.2 0.1 0.09 12.8 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KXX82379.1 - 0.18 11.8 2.8 4.1 7.4 0.0 3.0 3 1 1 4 4 3 0 Dynamin family Ribo_biogen_C PF04034.13 KXX82380.1 - 9.1e-50 167.7 0.0 1.2e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KXX82380.1 - 1.8e-12 46.9 0.7 3.7e-12 45.8 0.7 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Polyoma_lg_T_C PF06431.11 KXX82380.1 - 0.43 9.4 0.7 0.74 8.6 0.7 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus VHS PF00790.19 KXX82381.1 - 2.4e-44 150.6 0.0 9.1e-44 148.7 0.0 2.0 3 0 0 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.20 KXX82381.1 - 2.8e-22 79.1 5.6 1.6e-21 76.7 0.0 2.5 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 KXX82381.1 - 1.2e-19 70.3 0.8 3e-19 69.1 0.1 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KXX82381.1 - 2.5e-07 30.2 0.0 7.3e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 GGA N-GAT domain Transglut_C PF00927.22 KXX82381.1 - 0.1 12.8 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain AAA_16 PF13191.6 KXX82382.1 - 9.5e-07 29.4 0.8 4.1e-06 27.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KXX82382.1 - 1.9e-06 27.2 0.0 4.7e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain DUF676 PF05057.14 KXX82382.1 - 1.5e-05 24.7 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXX82382.1 - 0.0058 16.4 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.6 KXX82382.1 - 0.081 13.2 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain FHA PF00498.26 KXX82383.1 - 5.4e-16 58.7 0.0 1.2e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXX82383.1 - 0.0028 17.9 0.0 0.09 13.1 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CoA_trans PF01144.23 KXX82384.1 - 2e-96 321.6 0.3 1.5e-56 191.2 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KXX82384.1 - 0.0002 21.3 0.3 0.00038 20.4 0.3 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 KXX82384.1 - 0.00066 18.1 0.3 0.0016 16.9 0.1 1.5 1 1 0 2 2 2 1 Malonate decarboxylase, alpha subunit, transporter Terpene_synth_C PF03936.16 KXX82387.1 - 0.0015 18.0 0.1 0.0018 17.7 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain MARVEL PF01284.23 KXX82388.1 - 0.029 14.4 20.8 0.058 13.4 20.8 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF4293 PF14126.6 KXX82388.1 - 0.074 13.3 6.8 0.017 15.4 2.8 1.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4293) 7TMR-DISM_7TM PF07695.11 KXX82388.1 - 0.3 10.9 16.5 1 9.2 11.1 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF5337 PF17272.2 KXX82388.1 - 2.7 7.9 8.3 3.3 7.6 3.5 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5337) DUF1129 PF06570.11 KXX82388.1 - 5.3 6.5 8.8 1.5 8.3 5.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Egh16-like PF11327.8 KXX82389.1 - 1e-17 65.2 4.5 5.7e-15 56.2 1.6 2.4 1 1 1 2 2 2 2 Egh16-like virulence factor Xan_ur_permease PF00860.20 KXX82390.1 - 5.1e-65 219.7 31.9 8.3e-64 215.7 31.9 2.0 1 1 0 1 1 1 1 Permease family Mito_carr PF00153.27 KXX82392.1 - 4.4e-45 151.5 4.3 2e-14 53.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 KXX82393.1 - 7.2e-06 26.0 8.1 1.3e-05 25.2 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KXX82394.1 - 8.8e-30 104.0 0.0 1.3e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2517 PF10725.9 KXX82395.1 - 0.013 15.2 0.1 0.038 13.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) IBR PF01485.21 KXX82396.1 - 1.7e-21 76.2 47.4 7.7e-12 45.3 6.8 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXX82396.1 - 4.2e-05 23.3 42.4 0.00055 19.8 5.3 4.6 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX82396.1 - 0.0099 16.2 7.1 0.0099 16.2 7.1 4.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX82396.1 - 0.018 14.9 40.8 0.048 13.5 4.4 5.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX82396.1 - 0.56 10.3 36.0 0.035 14.1 5.5 3.9 3 1 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXX82396.1 - 2.7 8.2 31.7 1.4 9.2 1.6 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING CoA_trans PF01144.23 KXX82397.1 - 4.5e-99 330.2 0.6 1.5e-59 201.0 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KXX82397.1 - 0.0043 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SprT-like PF10263.9 KXX82398.1 - 2.9e-35 120.5 0.1 5.9e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KXX82398.1 - 2.7e-10 40.0 5.1 6.8e-10 38.7 5.1 1.8 1 0 0 1 1 1 1 SprT-like zinc ribbon domain HMG_box PF00505.19 KXX82398.1 - 0.00015 22.1 0.2 0.00075 19.9 0.2 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXX82398.1 - 0.002 18.7 0.1 0.011 16.3 0.1 2.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KXX82398.1 - 0.015 15.3 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 KXX82398.1 - 0.062 13.9 0.5 0.062 13.9 0.5 2.4 3 0 0 3 3 3 0 YABBY protein DUF4379 PF14311.6 KXX82398.1 - 0.28 11.6 7.8 0.091 13.1 1.9 3.0 3 0 0 3 3 3 0 Probable Zinc-ribbon domain CENP-B_dimeris PF09026.10 KXX82398.1 - 0.38 11.2 14.4 0.041 14.3 7.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Zn-ribbon_8 PF09723.10 KXX82398.1 - 7.3 6.8 6.8 1.3 9.3 2.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain DASH_Dam1 PF08653.10 KXX82399.1 - 4.2e-27 93.7 2.2 7.5e-27 92.9 2.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF4588 PF15251.6 KXX82399.1 - 0.088 12.6 3.0 0.14 11.9 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) Mog1 PF04603.12 KXX82400.1 - 4.2e-40 137.3 0.0 5.1e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein HIT PF01230.23 KXX82401.1 - 1e-20 74.3 0.2 1.6e-20 73.6 0.2 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXX82401.1 - 6.7e-11 42.7 0.0 1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXX82401.1 - 0.0001 22.2 0.1 0.00016 21.6 0.1 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF167 PF02594.16 KXX82402.1 - 1.6e-23 82.6 0.6 2.2e-23 82.2 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Redoxin PF08534.10 KXX82403.1 - 1e-27 96.6 0.0 1.3e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXX82403.1 - 1.2e-06 28.4 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glucan_synthase PF02364.15 KXX82404.1 - 0 1336.5 0.0 0 1335.8 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KXX82404.1 - 1.1e-43 148.7 0.4 3.2e-43 147.1 0.4 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 CRAL_TRIO PF00650.20 KXX82405.1 - 8.8e-46 155.5 0.1 1.6e-45 154.7 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXX82405.1 - 2.7e-13 49.9 0.1 6.4e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXX82405.1 - 3e-08 33.9 0.0 5.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain F_bP_aldolase PF01116.20 KXX82406.1 - 5.2e-91 305.0 0.0 5.9e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF2973 PF11189.8 KXX82406.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Aminotran_1_2 PF00155.21 KXX82407.1 - 2.1e-39 135.7 0.0 2.6e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXX82407.1 - 0.0026 16.3 0.0 0.0044 15.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KXX82407.1 - 0.011 14.5 0.0 0.046 12.4 0.0 2.0 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain BtpA PF03437.15 KXX82407.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 BtpA family MFS_1 PF07690.16 KXX82408.1 - 2.5e-38 131.9 75.0 8.7e-28 97.2 41.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX82408.1 - 1.4e-14 53.8 27.7 1.1e-08 34.4 10.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MutS_V PF00488.21 KXX82409.1 - 1.4e-67 227.4 0.1 2.6e-67 226.5 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXX82409.1 - 3e-41 141.8 0.0 6.1e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXX82409.1 - 8.6e-32 109.7 0.1 2.9e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KXX82409.1 - 1.1e-13 51.6 0.0 7.1e-13 49.0 0.0 2.4 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXX82409.1 - 1.5e-12 47.7 0.9 3.3e-12 46.6 0.9 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KXX82409.1 - 0.01 16.3 0.2 0.01 16.3 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXX82409.1 - 0.037 13.8 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 KXX82409.1 - 0.044 13.4 0.2 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KXX82409.1 - 1.1 9.0 6.4 0.11 12.3 0.2 2.4 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Mating_N PF12731.7 KXX82410.1 - 0.13 12.4 0.1 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Mating-type protein beta 1 Clr5 PF14420.6 KXX82411.1 - 1.5e-10 41.1 0.0 4.8e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Clr5 domain Cu-oxidase_4 PF02578.15 KXX82412.1 - 9.2e-27 94.1 0.0 1.2e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Ost5 PF05251.12 KXX82413.1 - 0.046 14.0 7.2 0.12 12.7 7.2 1.6 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Diphthamide_syn PF01866.17 KXX82414.1 - 8.1e-91 304.6 0.0 9.7e-91 304.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SET PF00856.28 KXX82415.1 - 2.9e-09 37.5 0.2 3.6e-08 34.0 0.2 2.4 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 KXX82415.1 - 0.0096 16.2 0.3 0.022 15.0 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat SAF PF08666.12 KXX82415.1 - 0.096 13.3 0.1 0.8 10.4 0.1 2.2 2 0 0 2 2 2 0 SAF domain Fasciclin PF02469.22 KXX82416.1 - 2e-41 141.2 0.2 4.1e-25 88.5 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain Peptidase_C12 PF01088.21 KXX82417.1 - 4.8e-40 137.6 0.0 5.6e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CP2 PF04516.15 KXX82419.1 - 1.5e-81 273.1 0.0 2.2e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KXX82419.1 - 0.046 12.5 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.8 KXX82419.1 - 0.07 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Oxysterol_BP PF01237.18 KXX82420.1 - 3.6e-48 164.3 0.0 5.8e-46 157.0 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein eIF2A PF08662.11 KXX82421.1 - 6.1e-76 254.6 0.0 1.9e-75 253.0 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KXX82421.1 - 1e-05 26.2 0.0 2.1 9.3 0.0 4.7 4 1 1 5 5 5 2 WD domain, G-beta repeat IATP PF04568.12 KXX82421.1 - 0.012 16.1 1.1 0.028 14.8 1.1 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP PAF-AH_p_II PF03403.13 KXX82422.1 - 8.6e-38 129.8 0.0 1e-32 113.2 0.0 2.0 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KXX82422.1 - 9.3e-06 25.1 0.2 0.014 14.7 0.1 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KXX82422.1 - 0.00078 18.4 0.0 0.0027 16.6 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KXX82422.1 - 0.0073 16.9 1.9 0.012 16.3 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KXX82422.1 - 0.049 12.6 0.1 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_5 PF12695.7 KXX82422.1 - 0.15 11.8 0.1 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Transformer PF06495.11 KXX82423.1 - 0.11 12.6 12.7 0.079 13.0 5.4 2.4 2 0 0 2 2 2 0 Fruit fly transformer protein SDP_N PF12278.8 KXX82423.1 - 4.6 7.4 6.3 17 5.5 2.2 2.4 2 0 0 2 2 2 0 Sex determination protein N terminal PRP38_assoc PF12871.7 KXX82423.1 - 8.2 7.1 22.7 2.9 8.6 2.1 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MFS_1 PF07690.16 KXX82424.1 - 2.8e-33 115.3 22.3 2.8e-33 115.3 22.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 KXX82424.1 - 0.043 12.6 8.9 0.11 11.3 3.8 2.2 2 0 0 2 2 2 0 POT family Sars6 PF12133.8 KXX82424.1 - 0.071 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus PIRT PF15099.6 KXX82424.1 - 0.69 9.5 4.5 2.2 7.8 0.1 3.0 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family DUF4131 PF13567.6 KXX82424.1 - 3.3 7.3 0.0 3.3 7.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) LIP PF03583.14 KXX82425.1 - 1.2e-38 133.0 0.0 2.5e-25 89.4 0.0 2.7 2 1 0 2 2 2 2 Secretory lipase p450 PF00067.22 KXX82427.1 - 4.7e-48 164.1 0.0 5.3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WSC PF01822.19 KXX82428.1 - 2e-31 108.0 29.4 2.3e-17 63.0 7.7 4.5 3 1 1 4 4 4 4 WSC domain Amidase PF01425.21 KXX82429.1 - 7.7e-91 305.3 0.0 1.3e-90 304.6 0.0 1.3 1 1 0 1 1 1 1 Amidase p450 PF00067.22 KXX82430.1 - 3.4e-12 45.9 0.0 4.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 gag_pre-integrs PF13976.6 KXX82431.1 - 0.001 18.8 0.0 0.001 18.8 0.0 2.3 2 1 1 3 3 3 1 GAG-pre-integrase domain Cript PF10235.9 KXX82431.1 - 0.0018 18.8 2.6 0.026 15.1 1.1 2.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT FYVE PF01363.21 KXX82431.1 - 0.0028 17.8 1.4 0.0035 17.4 0.2 1.8 2 0 0 2 2 2 1 FYVE zinc finger DZR PF12773.7 KXX82431.1 - 0.0049 16.9 1.7 0.059 13.4 0.5 2.4 2 0 0 2 2 2 1 Double zinc ribbon zinc-ribbon_6 PF10005.9 KXX82431.1 - 0.0095 16.6 2.1 0.068 13.9 1.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KXX82431.1 - 0.018 15.8 4.3 0.22 12.3 1.1 2.5 2 1 0 2 2 2 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KXX82431.1 - 0.026 13.9 1.4 0.026 13.9 1.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TENA_THI-4 PF03070.16 KXX82431.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Phage_sheath_1 PF04984.14 KXX82431.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain NOB1_Zn_bind PF08772.11 KXX82431.1 - 1.4 9.1 7.6 1.5 9.0 2.3 3.2 3 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like A2L_zn_ribbon PF08792.10 KXX82431.1 - 4.6 7.1 8.5 3 7.7 0.1 2.9 2 1 1 3 3 3 0 A2L zinc ribbon domain Retrotran_gag_2 PF14223.6 KXX82432.1 - 0.00078 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2795 PF11387.8 KXX82432.1 - 0.038 14.2 0.0 0.29 11.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2795) RVT_2 PF07727.14 KXX82433.1 - 5.2e-44 150.7 0.0 6.5e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cellulase PF00150.18 KXX82435.1 - 5.9e-56 189.9 4.9 6.8e-56 189.8 4.9 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5103 PF17116.5 KXX82435.1 - 0.035 13.4 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) Tcp11 PF05794.13 KXX82436.1 - 7.6e-103 344.9 0.4 7.6e-103 344.9 0.4 2.4 2 1 1 3 3 3 1 T-complex protein 11 DUF4170 PF13773.6 KXX82436.1 - 1 9.5 2.6 35 4.6 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) Fringe PF02434.16 KXX82437.1 - 2.7e-06 27.0 2.5 3.3e-05 23.4 2.5 2.3 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KXX82437.1 - 0.042 13.7 0.2 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Galactosyltransferase DUF604 PF04646.12 KXX82437.1 - 0.12 11.7 0.1 0.28 10.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF604 HEPN_SAV_6107 PF18726.1 KXX82438.1 - 0.08 13.4 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 SAV_6107-like HEPN PEPcase_2 PF14010.6 KXX82438.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Methyltransf_23 PF13489.6 KXX82439.1 - 2.5e-25 89.2 0.0 3.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82439.1 - 3e-11 43.9 0.0 7.9e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82439.1 - 2.3e-08 34.5 0.0 5.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX82439.1 - 2.6e-08 34.5 0.0 1.9e-07 31.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82439.1 - 6.3e-06 26.1 0.0 6.9e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXX82439.1 - 0.00099 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KXX82439.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KXX82439.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Ank_5 PF13857.6 KXX82440.1 - 7.1e-14 51.7 0.1 1.6e-06 28.3 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX82440.1 - 9.4e-09 35.6 0.8 0.35 11.5 0.0 4.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX82440.1 - 5.4e-08 33.3 0.0 0.0021 18.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX82440.1 - 0.00016 22.0 1.2 2.2 8.9 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KXX82440.1 - 0.0057 17.1 4.1 0.63 10.8 0.0 4.8 5 1 0 5 5 5 1 Ankyrin repeat DUF3678 PF12435.8 KXX82440.1 - 0.011 15.1 1.8 0.022 14.1 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Oxysterol_BP PF01237.18 KXX82441.1 - 6.1e-50 170.1 0.0 2.5e-43 148.4 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein FAD-oxidase_C PF02913.19 KXX82442.1 - 1.3e-59 201.9 0.0 2e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXX82442.1 - 2.1e-38 131.2 0.0 4.1e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ketoacyl-synt PF00109.26 KXX82443.1 - 8.1e-77 258.2 0.0 1.5e-76 257.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXX82443.1 - 1e-71 241.8 0.0 1.5e-71 241.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.10 KXX82443.1 - 1.1e-53 181.8 0.0 9e-52 175.6 0.0 2.5 2 0 0 2 2 2 1 KR domain Condensation PF00668.20 KXX82443.1 - 2.6e-51 174.7 0.1 4e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KXX82443.1 - 1.3e-48 165.8 0.0 2.4e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX82443.1 - 6.5e-41 140.9 0.3 1.3e-40 139.9 0.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX82443.1 - 2.5e-28 98.5 0.0 5.3e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KXX82443.1 - 9.7e-28 97.0 0.0 1.3e-26 93.3 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KXX82443.1 - 1.9e-17 63.8 0.0 1.1e-16 61.4 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXX82443.1 - 1.8e-15 57.4 0.0 4.6e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KXX82443.1 - 3.5e-13 49.6 0.0 9.1e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXX82443.1 - 9.9e-13 48.2 3.0 3e-06 27.5 0.2 3.7 4 0 0 4 4 3 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KXX82443.1 - 3.8e-10 40.3 0.0 5.8e-09 36.5 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82443.1 - 1.9e-09 38.0 0.0 7e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX82443.1 - 9.9e-09 34.9 0.0 7.9e-08 32.0 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KXX82443.1 - 1.9e-08 34.3 0.0 4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82443.1 - 2.9e-05 23.9 0.0 7.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 KXX82443.1 - 8.7e-05 22.5 0.0 0.002 18.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H-binding Thiolase_N PF00108.23 KXX82443.1 - 0.00011 21.7 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KXX82443.1 - 0.0063 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.19 KXX82443.1 - 0.14 11.1 0.0 0.99 8.4 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KXX82443.1 - 0.16 11.5 0.0 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KXX82443.1 - 0.19 11.1 0.0 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KXX82445.1 - 7.6e-16 57.9 0.1 1.9e-15 56.6 0.0 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Med3 PF11593.8 KXX82445.1 - 0.045 12.9 4.0 0.069 12.3 4.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Roughex PF06020.11 KXX82445.1 - 0.39 9.8 3.0 0.65 9.0 3.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 KXX82445.1 - 0.55 10.2 6.1 0.9 9.5 6.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 KXX82445.1 - 1.3 9.2 12.3 4.5 7.4 12.3 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KXX82445.1 - 1.5 8.4 8.0 2.9 7.5 8.0 1.4 1 0 0 1 1 1 0 Spt20 family DUF3682 PF12446.8 KXX82445.1 - 2.2 8.8 9.2 0.27 11.7 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) ADH_zinc_N PF00107.26 KXX82446.1 - 9e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX82446.1 - 0.00044 20.1 0.1 0.00098 19.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXX82446.1 - 0.027 14.4 0.3 5.9 6.8 0.0 2.5 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase K_oxygenase PF13434.6 KXX82447.1 - 3e-13 49.6 0.0 3.4e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXX82447.1 - 1.2e-08 34.6 0.0 0.00064 19.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX82447.1 - 2.7e-05 24.2 0.2 0.037 14.0 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXX82447.1 - 0.00013 21.4 0.0 0.0074 15.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXX82447.1 - 0.0018 17.6 0.0 0.039 13.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXX82447.1 - 0.0036 17.0 4.1 0.0059 16.2 0.8 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXX82447.1 - 0.0065 15.6 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXX82447.1 - 0.012 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KXX82447.1 - 0.013 15.7 0.3 0.088 13.1 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KXX82447.1 - 0.062 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KXX82447.1 - 0.08 11.6 0.0 0.34 9.5 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KXX82447.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KXX82447.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA VirE2 PF07229.12 KXX82447.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 VirE2 Phage_stabilise PF11134.8 KXX82447.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Phage stabilisation protein adh_short PF00106.25 KXX82448.1 - 2.9e-08 33.4 0.0 5.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82448.1 - 0.00075 19.1 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HTH_AsnC-type PF13404.6 KXX82448.1 - 0.0019 18.0 0.1 0.0059 16.4 0.0 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain KR PF08659.10 KXX82448.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 KR domain gp45-slide_C PF09116.10 KXX82448.1 - 0.16 12.1 0.0 0.51 10.4 0.0 1.7 2 0 0 2 2 2 0 gp45 sliding clamp, C terminal FA_hydroxylase PF04116.13 KXX82449.1 - 2.8e-21 76.2 16.7 6.7e-21 75.0 16.7 1.7 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Methyltransf_23 PF13489.6 KXX82449.1 - 6.6e-19 68.3 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82449.1 - 3.6e-08 33.3 0.0 2.8e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82449.1 - 5.7e-06 27.0 0.0 1.5e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82449.1 - 0.0004 21.0 0.0 0.00093 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KXX82449.1 - 0.21 11.0 0.0 0.46 10.0 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain GFO_IDH_MocA_C PF02894.17 KXX82450.1 - 3.3e-17 62.5 0.1 9.6e-17 61.1 0.1 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KXX82450.1 - 2e-14 54.4 0.0 3.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 KXX82451.1 - 4.1e-27 95.0 28.5 4.1e-27 95.0 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXX82452.1 - 1.9e-45 155.3 42.7 1.9e-45 155.3 42.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX82452.1 - 7e-12 44.9 8.3 7e-12 44.9 8.3 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KXX82452.1 - 7.4e-06 25.5 6.6 7.4e-06 25.5 6.6 2.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KXX82452.1 - 0.0012 17.3 7.9 0.0012 17.3 7.9 2.8 1 1 1 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 KXX82452.1 - 4.7 5.4 13.8 3.1 6.0 6.6 3.0 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 KXX82454.1 - 8.9e-17 61.2 0.0 1.1e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82454.1 - 3.4e-12 46.4 0.0 4.1e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82454.1 - 4.5e-09 36.5 0.0 7.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXX82454.1 - 0.0002 21.6 0.1 0.018 15.3 0.2 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain RNA_pol_Rpb6 PF01192.22 KXX82454.1 - 0.0042 17.0 0.7 0.0071 16.3 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 NAD_binding_10 PF13460.6 KXX82454.1 - 0.055 13.3 0.2 0.079 12.9 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXX82454.1 - 0.057 12.5 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXX82454.1 - 0.062 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KXX82454.1 - 0.062 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXX82454.1 - 0.12 11.7 0.1 0.34 10.2 0.0 1.8 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.16 KXX82455.1 - 3.1e-25 88.9 35.6 5.9e-24 84.7 31.8 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily YqjK PF13997.6 KXX82455.1 - 0.00025 21.2 0.2 0.51 10.6 0.4 2.6 2 0 0 2 2 2 2 YqjK-like protein Sugar_tr PF00083.24 KXX82455.1 - 0.0043 16.0 17.0 0.0084 15.0 16.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter CorA PF01544.18 KXX82456.1 - 6.7e-08 32.2 0.2 6.7e-08 32.2 0.2 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Ureide_permease PF07168.11 KXX82456.1 - 0.012 14.4 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 0 Ureide permease Ammonium_transp PF00909.21 KXX82456.1 - 0.043 12.5 1.6 0.057 12.1 1.6 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family Patched PF02460.18 KXX82456.1 - 0.47 8.5 5.1 5.1 5.0 0.1 2.1 1 1 1 2 2 2 0 Patched family CD225 PF04505.12 KXX82456.1 - 0.82 9.9 0.1 0.82 9.9 0.1 2.6 3 1 0 3 3 3 0 Interferon-induced transmembrane protein SLAC1 PF03595.17 KXX82457.1 - 2.9e-73 246.9 43.6 3.4e-73 246.7 43.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel FAD_binding_3 PF01494.19 KXX82458.1 - 3.5e-16 59.4 0.0 7.5e-16 58.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX82458.1 - 1.1e-06 28.5 0.0 0.044 13.4 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX82458.1 - 4.1e-06 26.2 0.0 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX82458.1 - 0.00029 21.3 0.0 0.035 14.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXX82458.1 - 0.0017 17.3 0.0 0.3 9.9 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KXX82458.1 - 0.02 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 KXX82458.1 - 0.25 10.4 0.0 1.8 7.6 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase DUF3429 PF11911.8 KXX82459.1 - 2.8e-43 147.7 10.3 3.7e-43 147.3 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Peptidase_S49_N PF08496.10 KXX82459.1 - 0.0098 16.0 4.8 0.019 15.0 4.8 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Transgly_assoc PF04226.13 KXX82459.1 - 0.11 12.7 2.4 0.48 10.7 0.2 2.3 2 0 0 2 2 2 0 Transglycosylase associated protein DUF4834 PF16118.5 KXX82459.1 - 0.12 13.4 2.5 0.18 12.8 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) U79_P34 PF03064.16 KXX82459.1 - 1.1 8.5 11.6 1.7 8.0 11.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4770 PF15994.5 KXX82459.1 - 9.9 6.4 8.3 27 4.9 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) VPS13_mid_rpt PF16910.5 KXX82464.1 - 1.3e-94 316.1 8.9 6.7e-90 300.6 0.3 5.9 5 1 1 6 6 6 4 Repeating coiled region of VPS13 VPS13 PF16908.5 KXX82464.1 - 1.1e-87 293.8 0.0 9.4e-86 287.4 0.0 3.1 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 KXX82464.1 - 6.4e-87 291.4 0.0 2.1e-85 286.4 0.0 2.6 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 KXX82464.1 - 3.9e-76 254.8 5.4 8.1e-71 237.5 0.3 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KXX82464.1 - 1.3e-39 134.9 0.1 4.9e-39 133.0 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KXX82464.1 - 5.8e-07 29.8 0.3 2.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain MFS_1 PF07690.16 KXX82466.1 - 2.3e-24 86.0 23.6 2.3e-24 86.0 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX82466.1 - 0.0013 17.3 3.5 0.0023 16.5 3.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1966 PF09260.11 KXX82467.1 - 3.1e-15 56.2 0.5 4.6e-15 55.7 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Peptidase_M1 PF01433.20 KXX82468.1 - 2.8e-81 272.3 2.1 4.3e-81 271.6 2.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KXX82468.1 - 7.2e-78 262.3 0.0 1.8e-76 257.7 0.0 2.3 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KXX82468.1 - 7.5e-47 159.9 0.5 2.4e-46 158.3 0.1 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 KXX82468.1 - 0.0026 17.8 0.0 0.0079 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 Peptidase_M50 PF02163.22 KXX82468.1 - 0.074 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M50 SprT-like PF10263.9 KXX82468.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 SprT-like family DUF1479 PF07350.12 KXX82469.1 - 1.3e-152 508.4 0.0 1.7e-152 508.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) FAD_binding_2 PF00890.24 KXX82470.1 - 6.4e-89 298.9 0.1 7.4e-89 298.7 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX82470.1 - 8e-07 29.2 0.0 3.3e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX82470.1 - 1.2e-05 25.1 0.0 0.00022 20.9 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KXX82470.1 - 1.6e-05 24.2 0.1 1.6e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KXX82470.1 - 6.5e-05 22.3 0.1 0.00054 19.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX82470.1 - 8.7e-05 21.4 1.3 0.0019 17.0 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXX82470.1 - 9e-05 21.9 0.1 0.00034 20.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KXX82470.1 - 0.00055 19.4 0.0 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX82470.1 - 0.001 18.4 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXX82470.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX82470.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXX82470.1 - 0.43 9.6 1.3 0.53 9.3 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein SAD_SRA PF02182.17 KXX82471.1 - 1.1e-34 119.4 0.1 1.6e-34 118.8 0.1 1.3 1 0 0 1 1 1 1 SAD/SRA domain Sugar_tr PF00083.24 KXX82472.1 - 7.9e-104 348.0 31.6 1e-103 347.7 31.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX82472.1 - 2.1e-25 89.4 35.7 3.2e-22 79.0 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SGL PF08450.12 KXX82473.1 - 0.016 14.8 1.3 2.7 7.5 0.2 2.8 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXX82473.1 - 0.021 14.9 3.1 7.2 6.9 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Aldo_ket_red PF00248.21 KXX82475.1 - 7.1e-72 242.1 0.0 8e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2235 PF09994.9 KXX82476.1 - 5.3e-71 239.3 0.1 4.1e-44 151.1 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) OHCU_decarbox PF09349.10 KXX82477.1 - 1e-49 169.0 0.6 1.2e-49 168.8 0.6 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Granin PF01271.17 KXX82477.1 - 0.075 11.9 6.1 0.091 11.7 6.1 1.1 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) DUF4404 PF14357.6 KXX82477.1 - 0.091 13.4 2.1 0.24 12.0 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Methyltransf_23 PF13489.6 KXX82478.1 - 6.6e-19 68.3 0.0 9.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82478.1 - 7.6e-12 45.8 0.0 2.6e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82478.1 - 4.9e-11 43.1 0.0 1.1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX82478.1 - 1.3e-07 32.2 0.0 1.7e-06 28.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82478.1 - 2.8e-06 27.2 0.0 1.3e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX82478.1 - 4.1e-06 26.3 0.0 3.3e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KXX82478.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXX82478.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KXX82478.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.13 KXX82478.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PUL PF08324.11 KXX82478.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 PUL domain TPMT PF05724.11 KXX82479.1 - 5.4e-29 101.4 0.0 7.6e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 KXX82479.1 - 1.8e-08 35.1 0.0 3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82479.1 - 2e-08 34.8 0.0 7.3e-07 29.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX82479.1 - 4e-08 33.3 0.0 6.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82479.1 - 1.2e-07 32.3 0.0 2.3e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82479.1 - 1.9e-05 24.5 0.0 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXX82479.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KXX82479.1 - 0.028 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Peptidase_MA_2 PF13485.6 KXX82479.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase MA superfamily Ank_5 PF13857.6 KXX82480.1 - 3.4e-11 43.2 0.3 1.1e-06 28.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX82480.1 - 2.6e-10 40.6 1.5 0.0041 17.7 0.1 5.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX82480.1 - 2.7e-10 40.7 0.2 1.6e-05 25.4 0.1 3.6 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX82480.1 - 3e-08 33.3 0.3 0.0064 16.9 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KXX82480.1 - 5.5e-08 32.9 0.5 0.011 16.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat YhdB PF14148.6 KXX82480.1 - 0.2 11.8 0.1 2 8.6 0.0 2.3 2 0 0 2 2 2 0 YhdB-like protein EthD PF07110.11 KXX82482.1 - 0.00031 21.8 0.0 0.00041 21.5 0.0 1.2 1 0 0 1 1 1 1 EthD domain ADH_N PF08240.12 KXX82483.1 - 2.8e-26 91.5 4.2 4.6e-26 90.8 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX82483.1 - 4e-16 59.2 0.0 7.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX82483.1 - 0.0016 19.5 0.0 0.0026 18.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXX82483.1 - 0.0029 17.0 0.2 0.01 15.2 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXX82483.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Chs7 PF12271.8 KXX82484.1 - 5.1e-124 413.3 14.6 5.8e-124 413.1 14.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Cyclin PF08613.11 KXX82485.1 - 7.3e-11 42.7 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXX82485.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Aldo_ket_red PF00248.21 KXX82486.1 - 3.3e-41 141.4 0.0 8.3e-34 117.1 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Fungal_trans PF04082.18 KXX82487.1 - 1.3e-21 76.8 1.7 2.1e-21 76.2 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82487.1 - 9.2e-08 32.1 11.6 1.8e-07 31.1 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KXX82487.1 - 5.3 7.1 11.8 0.36 10.8 6.2 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat p450 PF00067.22 KXX82488.1 - 2.1e-53 181.7 0.0 2e-38 132.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SnoaL_4 PF13577.6 KXX82489.1 - 1.4e-09 38.2 0.0 2.7e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain Spc7 PF08317.11 KXX82490.1 - 8.1e-07 28.2 102.6 0.0015 17.4 14.9 6.2 1 1 4 6 6 6 5 Spc7 kinetochore protein Filament PF00038.21 KXX82490.1 - 2.9e-06 27.1 89.4 6e-05 22.8 8.8 3.8 1 1 1 3 3 3 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 KXX82490.1 - 1.3e-05 25.2 97.8 0.00017 21.7 4.7 7.4 1 1 7 8 8 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 KXX82490.1 - 0.00058 19.9 4.6 0.00058 19.9 4.6 9.7 3 2 5 9 9 8 2 Designed helical repeat protein 10 domain DUF5082 PF16888.5 KXX82490.1 - 0.0027 18.0 3.6 0.0027 18.0 3.6 9.1 2 2 4 7 7 6 3 Domain of unknown function (DUF5082) Cortex-I_coil PF09304.10 KXX82490.1 - 0.0062 16.7 10.8 0.0062 16.7 10.8 8.5 2 2 5 7 7 5 2 Cortexillin I, coiled coil ABC_tran_CTD PF16326.5 KXX82490.1 - 0.0063 16.7 5.5 0.0063 16.7 5.5 11.0 3 2 9 12 12 11 3 ABC transporter C-terminal domain DUF724 PF05266.14 KXX82490.1 - 0.0079 16.0 4.2 0.0079 16.0 4.2 7.5 2 2 6 8 8 8 4 Protein of unknown function (DUF724) CENP-Q PF13094.6 KXX82490.1 - 0.0083 16.3 5.0 0.0083 16.3 5.0 7.0 2 1 5 7 7 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF812 PF05667.11 KXX82490.1 - 0.012 14.5 84.5 0.013 14.5 13.8 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF812) APG6_N PF17675.1 KXX82490.1 - 0.016 15.8 9.2 0.016 15.8 9.2 8.4 1 1 5 7 7 6 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 KXX82490.1 - 0.047 13.7 39.1 0.9 9.6 1.5 6.8 4 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.19 KXX82490.1 - 0.18 9.6 106.5 0.025 12.4 15.8 3.9 1 1 2 3 3 2 0 Myosin tail DUF1664 PF07889.12 KXX82490.1 - 0.23 11.5 56.9 0.58 10.2 3.5 8.3 2 2 7 10 10 10 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KXX82490.1 - 0.58 10.6 89.8 0.13 12.7 13.6 5.7 1 1 4 5 5 5 0 Fez1 Pox_A_type_inc PF04508.12 KXX82490.1 - 0.65 9.9 14.5 1.6 8.7 0.6 6.9 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat DUF3584 PF12128.8 KXX82490.1 - 1.1 6.7 105.2 0.08 10.4 50.2 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 KXX82490.1 - 1.4 9.0 112.7 0.12 12.4 10.5 8.2 2 2 6 8 8 7 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 KXX82490.1 - 1.7 8.6 16.5 9.5 6.2 0.0 6.4 7 1 0 7 7 6 0 Shugoshin N-terminal coiled-coil region BLOC1_2 PF10046.9 KXX82490.1 - 4.7 7.6 54.9 0.071 13.4 1.0 8.4 3 1 6 9 9 9 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APC_N_CC PF16689.5 KXX82490.1 - 5.6 7.1 11.6 3.6 7.7 2.9 4.7 3 2 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain GIT_SHD PF08518.11 KXX82492.1 - 3.1e-08 33.1 5.5 3.7e-08 32.8 2.7 2.4 2 0 0 2 2 2 1 Spa2 homology domain (SHD) of GIT DUF3435 PF11917.8 KXX82493.1 - 0.0076 15.2 2.1 0.01 14.8 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Vps54 PF07928.12 KXX82495.1 - 6.6e-27 94.6 0.7 7.3e-25 88.0 0.1 3.4 2 1 1 3 3 3 2 Vps54-like protein DUF2451 PF10474.9 KXX82495.1 - 0.00073 19.4 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KXX82495.1 - 0.0063 15.8 0.1 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF5364 PF17322.2 KXX82495.1 - 0.023 15.0 1.2 0.033 14.5 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5364) MFS_1 PF07690.16 KXX82496.1 - 1.3e-37 129.5 58.4 3.2e-37 128.3 55.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX82496.1 - 2.2e-07 30.1 10.3 2.2e-07 30.1 10.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1418 PF07214.12 KXX82496.1 - 0.034 14.0 1.8 0.64 9.9 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) Corona_S2 PF01601.16 KXX82496.1 - 1.9 6.9 6.0 0.3 9.5 2.0 1.5 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein DUF2681 PF10883.8 KXX82497.1 - 1.9 9.0 6.4 1.8 9.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Ctr PF04145.15 KXX82498.1 - 7.3e-40 137.0 0.4 9e-40 136.7 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 KXX82498.1 - 0.2 11.4 5.1 0.72 9.6 4.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YfhO PF09586.10 KXX82498.1 - 1.7 6.8 10.6 0.48 8.6 6.2 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DIT1_PvcA PF05141.12 KXX82499.1 - 1.2e-104 349.7 0.0 1.6e-104 349.3 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF3716 PF12511.8 KXX82500.1 - 2.1e-07 30.9 4.9 3.7e-07 30.1 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Ribosomal_S6 PF01250.17 KXX82501.1 - 9.1e-18 64.3 0.0 1.1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Arrestin_C PF02752.22 KXX82502.1 - 2.5e-14 53.9 0.0 1.4e-13 51.5 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXX82502.1 - 2.3e-07 31.0 2.5 0.002 18.2 0.0 2.8 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF5621 PF18532.1 KXX82502.1 - 0.11 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) SurE PF01975.17 KXX82503.1 - 1e-28 100.5 0.3 1.4e-28 100.0 0.3 1.2 1 0 0 1 1 1 1 Survival protein SurE Fungal_trans PF04082.18 KXX82504.1 - 1.4e-05 24.3 0.2 2.4e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82504.1 - 0.0045 17.1 10.6 0.0071 16.4 0.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_viral_C PF00336.18 KXX82504.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain SCIMP PF15050.6 KXX82505.1 - 0.0054 17.2 0.1 0.0068 16.9 0.1 1.1 1 0 0 1 1 1 1 SCIMP protein SNARE_assoc PF09335.11 KXX82505.1 - 0.014 15.9 0.3 0.017 15.6 0.3 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein EVC2_like PF12297.8 KXX82505.1 - 0.022 13.4 0.0 0.023 13.4 0.0 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Adeno_E3_CR2 PF02439.15 KXX82505.1 - 0.032 14.0 4.6 0.062 13.1 4.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Comm PF15957.5 KXX82505.1 - 0.059 13.7 0.0 0.061 13.7 0.0 1.1 1 0 0 1 1 1 0 Commissureless Amnionless PF14828.6 KXX82505.1 - 0.07 12.0 0.0 0.072 11.9 0.0 1.0 1 0 0 1 1 1 0 Amnionless MtrF PF09472.10 KXX82505.1 - 0.12 11.8 0.7 0.2 11.1 0.7 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MLANA PF14991.6 KXX82505.1 - 0.14 12.5 0.1 0.14 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein melan-A Fungal_trans_2 PF11951.8 KXX82506.1 - 5.7e-27 94.5 0.8 8.1e-27 94.0 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82506.1 - 4e-07 30.0 8.0 6.9e-07 29.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.20 KXX82507.1 - 4.9e-26 90.7 0.0 6.1e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXX82507.1 - 9.2e-07 29.3 0.1 9.3e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXX82507.1 - 4.7e-06 26.2 0.0 5.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXX82507.1 - 0.0013 18.6 0.1 0.0081 16.1 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXX82507.1 - 0.0041 17.4 0.0 0.033 14.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXX82507.1 - 0.0073 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXX82507.1 - 0.0096 15.7 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KXX82507.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.16 KXX82507.1 - 0.04 13.7 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 PX PF00787.24 KXX82509.1 - 2.3e-18 66.2 0.1 4.5e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 PX domain Cullin_binding PF03556.15 KXX82510.1 - 8.8e-29 100.4 6.4 1.5e-28 99.7 6.4 1.3 1 0 0 1 1 1 1 Cullin binding Peptidase_S8 PF00082.22 KXX82512.1 - 9.1e-09 35.0 0.0 2.9e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 KXX82513.1 - 1.1e-50 170.1 15.9 5.1e-10 39.8 0.3 6.5 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX82513.1 - 9.4e-36 121.8 9.3 1e-06 29.2 0.0 11.0 7 2 5 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX82513.1 - 3.5e-23 79.2 12.1 1.8 9.4 0.0 15.1 15 0 0 15 15 14 3 Ankyrin repeat Ank PF00023.30 KXX82513.1 - 2.8e-17 62.3 36.2 1.5 9.4 0.1 14.6 15 0 0 15 15 14 5 Ankyrin repeat Ank_5 PF13857.6 KXX82513.1 - 6.7e-14 51.8 24.6 0.29 11.5 0.2 12.2 4 3 7 12 12 12 4 Ankyrin repeats (many copies) AAA_22 PF13401.6 KXX82513.1 - 9.9e-07 29.1 0.0 2.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX82513.1 - 8.7e-05 23.0 0.1 0.00036 21.0 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXX82513.1 - 0.00073 19.5 0.6 0.002 18.1 0.6 1.7 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KXX82513.1 - 0.0029 16.9 0.0 0.086 12.1 0.0 2.2 1 1 1 2 2 2 1 KAP family P-loop domain DUF629 PF04780.12 KXX82513.1 - 0.038 12.5 0.0 0.069 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) AAA_5 PF07728.14 KXX82513.1 - 0.12 12.4 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PIF1 PF05970.14 KXX82513.1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase GIT1_C PF12205.8 KXX82513.1 - 0.19 11.8 0.6 1.5 9.0 0.3 2.3 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term LIM PF00412.22 KXX82513.1 - 0.25 11.6 0.4 0.54 10.5 0.4 1.5 1 0 0 1 1 1 0 LIM domain Ribosomal_L27A PF00828.19 KXX82514.1 - 2.3e-30 105.9 0.2 3.4e-30 105.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GST_N PF02798.20 KXX82515.1 - 5.7e-12 45.8 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXX82515.1 - 2.8e-09 36.9 0.0 5.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX82515.1 - 6.9e-09 36.0 0.0 2.1e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXX82515.1 - 1.5e-08 34.7 0.0 2.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX82515.1 - 8.2e-08 32.4 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXX82515.1 - 1.3e-07 31.8 0.0 3.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXX82515.1 - 0.1 13.2 0.0 0.22 12.1 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain p450 PF00067.22 KXX82516.1 - 6.1e-65 219.8 0.0 7.8e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KXX82517.1 - 1e-25 90.6 0.2 8e-20 71.4 0.1 2.4 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KXX82517.1 - 4.6e-08 33.2 0.1 6.6e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXX82517.1 - 0.0097 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KXX82518.1 - 7.7e-21 74.6 0.0 1.5e-20 73.7 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82518.1 - 1.8e-13 51.0 0.0 5.1e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82518.1 - 8e-11 42.0 0.0 0.00014 21.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82518.1 - 6.2e-10 39.6 0.0 1.5e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX82518.1 - 2e-09 38.0 0.0 7.9e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXX82518.1 - 0.00048 19.6 0.1 0.0015 18.0 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXX82518.1 - 0.00099 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXX82518.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KXX82518.1 - 0.019 14.3 0.0 0.043 13.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXX82518.1 - 0.019 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXX82518.1 - 0.049 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 KXX82518.1 - 0.11 11.8 0.0 0.8 9.0 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Osmo_MPGsynth PF09488.10 KXX82519.1 - 8.9e-139 462.5 0.0 1e-138 462.3 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) EHN PF06441.12 KXX82521.1 - 3e-28 98.3 0.0 5.3e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXX82521.1 - 9.5e-08 32.0 0.1 1.4e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PAM2 PF07145.15 KXX82523.1 - 0.0023 17.5 0.4 0.0065 16.1 0.4 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region NAD_binding_10 PF13460.6 KXX82524.1 - 4.7e-15 56.0 0.0 6.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXX82524.1 - 0.046 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ACC_epsilon PF13822.6 KXX82524.1 - 0.16 12.7 0.9 14 6.4 0.7 2.5 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Hydrolase_4 PF12146.8 KXX82525.1 - 3.4e-06 26.5 0.1 0.037 13.3 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX82525.1 - 1.5e-05 24.8 0.0 3e-05 23.8 0.0 1.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KXX82525.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXX82525.1 - 0.00032 20.2 0.6 0.15 11.5 0.6 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXX82525.1 - 0.0018 18.9 5.5 0.0038 17.9 5.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KXX82525.1 - 0.003 17.4 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX82525.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FAD_binding_3 PF01494.19 KXX82526.1 - 2.4e-75 254.0 0.0 3.1e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXX82526.1 - 1.2e-45 155.6 0.0 1.9e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 KXX82526.1 - 0.00053 19.7 0.3 0.071 12.7 0.1 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX82526.1 - 0.00065 19.0 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXX82526.1 - 0.0026 16.9 0.0 0.0069 15.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX82526.1 - 0.0057 15.9 0.1 0.21 10.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXX82526.1 - 0.0061 16.0 0.0 0.012 14.9 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KXX82526.1 - 0.074 12.1 0.0 0.37 9.8 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.6 KXX82526.1 - 0.078 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXX82526.1 - 0.085 12.1 0.1 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SNN_linker PF09050.10 KXX82526.1 - 0.13 12.0 1.0 0.32 10.8 1.0 1.6 1 0 0 1 1 1 0 Stannin unstructured linker PP2C PF00481.21 KXX82527.1 - 1.4e-35 123.2 0.0 3.3e-30 105.6 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXX82527.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein phosphatase 2C YrzK PF17449.2 KXX82527.1 - 0.12 12.7 0.1 0.36 11.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized YrzK-like RRM_1 PF00076.22 KXX82528.1 - 2.8e-42 142.4 1.5 1.2e-19 69.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXX82528.1 - 4.1e-23 82.3 0.1 1.4e-22 80.6 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KXX82528.1 - 5.7e-05 22.9 0.0 0.25 11.3 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KXX82528.1 - 0.0022 18.0 0.7 0.11 12.5 0.0 3.0 3 1 0 3 3 3 1 RNA binding motif PHM7_cyt PF14703.6 KXX82528.1 - 0.0043 17.3 0.1 0.2 11.9 0.1 3.4 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KXX82528.1 - 0.01 15.9 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KXX82528.1 - 0.02 14.9 0.0 2.8 8.0 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXX82528.1 - 0.06 12.9 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAG6 PF12057.8 KXX82529.1 - 0.062 13.0 0.2 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 BCL2-associated athanogene 6 Topo_Zn_Ribbon PF08272.11 KXX82529.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like MetOD2 PF18548.1 KXX82529.1 - 0.19 11.9 1.1 0.66 10.1 0.5 2.2 2 1 0 2 2 2 0 Metanogen output domain 2 DUF4763 PF15960.5 KXX82529.1 - 0.35 10.1 6.4 0.39 10.0 3.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) KASH_CCD PF14662.6 KXX82529.1 - 0.4 10.5 9.6 1.5 8.6 5.2 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH CtIP_N PF10482.9 KXX82529.1 - 0.59 10.2 5.3 8.6 6.4 4.5 2.4 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Lzipper-MIP1 PF14389.6 KXX82529.1 - 0.78 10.1 4.3 7.9 6.9 2.4 2.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 bZIP_2 PF07716.15 KXX82531.1 - 1.6e-12 47.3 9.7 3e-12 46.4 9.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXX82531.1 - 0.00045 20.3 8.5 0.00095 19.2 8.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.9 KXX82531.1 - 0.025 14.8 2.5 0.052 13.7 2.5 1.5 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.18 KXX82531.1 - 0.032 14.5 0.1 0.065 13.6 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family CENP-N PF05238.13 KXX82532.1 - 1.5e-134 449.5 0.0 8.8e-134 446.9 0.0 1.9 1 1 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.21 KXX82533.1 - 4.4e-47 160.6 0.0 1e-46 159.4 0.0 1.6 1 1 0 1 1 1 1 TatD related DNase Androgen_recep PF02166.16 KXX82533.1 - 2 7.2 7.2 1 8.1 4.2 1.8 2 0 0 2 2 2 0 Androgen receptor Ribosomal_60s PF00428.19 KXX82533.1 - 2.6 8.7 7.7 7.1 7.3 6.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribonuc_red_lgC PF02867.15 KXX82534.1 - 7.5e-194 645.1 0.0 9.5e-194 644.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KXX82534.1 - 8.8e-24 83.3 0.0 2.1e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KXX82534.1 - 2.7e-17 63.1 0.0 5.7e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain AAA PF00004.29 KXX82535.1 - 2.2e-49 167.3 0.0 5.2e-42 143.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX82535.1 - 1.3e-10 40.9 0.1 1.4e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KXX82535.1 - 7.9e-07 29.6 0.7 0.00099 19.5 0.3 3.4 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KXX82535.1 - 1.4e-06 28.2 0.0 3.6e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXX82535.1 - 2.9e-05 24.3 0.0 6.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXX82535.1 - 0.00016 21.7 0.1 0.014 15.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX82535.1 - 0.0012 19.1 0.3 0.063 13.5 0.2 3.3 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KXX82535.1 - 0.0013 18.9 1.5 0.035 14.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KXX82535.1 - 0.0015 18.3 0.0 0.038 13.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXX82535.1 - 0.003 18.1 0.8 0.042 14.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KXX82535.1 - 0.0093 16.3 0.0 0.035 14.5 0.0 2.0 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KXX82535.1 - 0.01 15.1 0.0 0.025 13.8 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KXX82535.1 - 0.022 14.2 0.3 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KXX82535.1 - 0.042 12.9 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KXX82535.1 - 0.052 13.8 0.2 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KXX82535.1 - 0.059 13.2 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KXX82535.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Bromodomain NACHT PF05729.12 KXX82535.1 - 0.065 13.1 0.0 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.6 KXX82535.1 - 0.073 13.2 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Torsin PF06309.11 KXX82535.1 - 0.079 13.1 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_7 PF12775.7 KXX82535.1 - 0.08 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXX82535.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXX82535.1 - 0.11 12.1 0.0 4 7.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_11 PF13086.6 KXX82535.1 - 0.75 9.5 0.0 0.75 9.5 0.0 3.5 3 1 0 3 3 1 0 AAA domain FAM83 PF07894.12 KXX82536.1 - 0.1 12.2 0.6 0.18 11.3 0.6 1.4 1 0 0 1 1 1 0 FAM83 A-H DUF2315 PF10231.9 KXX82536.1 - 0.21 11.7 0.9 0.42 10.7 0.8 1.5 1 1 0 1 1 1 0 Apoptogenic protein 1 adh_short PF00106.25 KXX82537.1 - 2.4e-24 85.9 0.5 3.2e-15 56.1 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82537.1 - 6.6e-18 65.1 0.6 4.3e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82537.1 - 0.00018 21.5 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX82537.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RNA_pol_I_A49 PF06870.12 KXX82538.1 - 1.4e-94 317.1 1.9 1.7e-94 316.9 1.9 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Arfaptin PF06456.13 KXX82538.1 - 0.11 12.1 1.7 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Arfaptin-like domain DUF4423 PF14394.6 KXX82538.1 - 2.6 7.7 5.8 1 9.1 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4423) CTK3 PF12243.8 KXX82539.1 - 1.9e-50 170.0 0.4 2.7e-50 169.5 0.4 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KXX82539.1 - 1.5e-20 73.1 11.7 1.5e-20 73.1 11.7 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus P5CR_dimer PF14748.6 KXX82540.1 - 3.5e-36 123.6 1.2 7.1e-36 122.6 1.2 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXX82540.1 - 8.9e-15 55.1 2.3 1.7e-12 47.8 0.1 2.6 1 1 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 KXX82540.1 - 0.059 12.4 0.0 0.29 10.1 0.0 1.9 1 1 0 1 1 1 0 Prephenate dehydrogenase AAA_5 PF07728.14 KXX82541.1 - 4.6e-122 402.4 0.0 3.2e-21 75.8 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KXX82541.1 - 1.5e-53 179.5 9.2 7.6e-19 67.9 0.0 5.9 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_16 PF13191.6 KXX82541.1 - 1e-30 107.4 24.6 3e-05 24.5 0.2 9.3 7 2 0 8 8 7 6 AAA ATPase domain AAA_lid_5 PF17865.1 KXX82541.1 - 2.4e-30 104.7 0.2 2.4e-30 104.7 0.2 3.0 3 0 0 3 3 1 1 Midasin AAA lid domain AAA_7 PF12775.7 KXX82541.1 - 8.1e-30 103.7 0.1 2.5e-05 23.9 0.0 6.9 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_3 PF07726.11 KXX82541.1 - 1.2e-29 102.8 0.0 2.6e-10 40.3 0.0 7.2 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KXX82541.1 - 1e-27 97.1 0.0 8.9e-05 22.9 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXX82541.1 - 3.2e-25 89.0 0.6 0.0013 19.0 0.0 8.6 7 0 0 7 7 6 6 AAA domain Dynein_heavy PF03028.15 KXX82541.1 - 2.4e-24 85.7 0.0 8.3e-05 22.7 0.0 8.1 7 0 0 7 7 7 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 KXX82541.1 - 3.6e-21 75.6 0.0 0.0036 17.0 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_6 PF12774.7 KXX82541.1 - 2.3e-19 69.5 0.0 0.0052 15.8 0.0 8.7 9 0 0 9 9 9 3 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 KXX82541.1 - 6.7e-19 68.2 0.0 0.0023 17.9 0.0 7.7 8 0 0 8 8 7 4 AAA domain AAA_18 PF13238.6 KXX82541.1 - 2.1e-18 67.1 0.4 0.0053 17.3 0.0 7.3 6 0 0 6 6 6 3 AAA domain AAA_33 PF13671.6 KXX82541.1 - 6.1e-18 65.4 0.2 0.093 12.9 0.0 7.3 6 0 0 6 6 6 4 AAA domain TsaE PF02367.17 KXX82541.1 - 5e-16 58.8 3.6 0.005 16.8 0.1 6.3 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KXX82541.1 - 5.8e-16 59.3 11.3 0.008 16.7 0.0 8.5 8 0 0 8 8 7 4 ABC transporter AAA_30 PF13604.6 KXX82541.1 - 8.9e-16 58.2 0.0 0.0027 17.5 0.0 7.4 6 1 0 6 6 6 1 AAA domain NACHT PF05729.12 KXX82541.1 - 2.8e-14 53.4 5.7 0.17 11.8 0.0 6.4 5 0 0 5 5 5 4 NACHT domain RNA_helicase PF00910.22 KXX82541.1 - 8.3e-14 51.9 0.4 1.3 9.4 0.0 6.7 6 0 0 6 6 6 2 RNA helicase Sigma54_activ_2 PF14532.6 KXX82541.1 - 1.2e-13 51.4 0.7 7.1e-05 22.9 0.0 6.4 7 0 0 7 7 5 2 Sigma-54 interaction domain RsgA_GTPase PF03193.16 KXX82541.1 - 2.5e-13 50.3 3.7 0.058 13.3 0.0 6.7 7 0 0 7 7 6 3 RsgA GTPase T2SSE PF00437.20 KXX82541.1 - 7.8e-13 48.1 6.6 0.011 14.8 0.0 7.1 8 0 0 8 8 7 3 Type II/IV secretion system protein RuvB_N PF05496.12 KXX82541.1 - 9.5e-12 44.9 1.7 0.32 10.7 0.0 6.3 6 0 0 6 6 5 3 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KXX82541.1 - 1.8e-11 43.7 0.5 0.09 12.1 0.0 6.8 6 0 0 6 6 6 1 Zeta toxin AAA_29 PF13555.6 KXX82541.1 - 2.3e-11 43.3 0.1 0.035 13.8 0.0 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXX82541.1 - 4.1e-11 42.7 1.0 1.4 8.3 0.1 7.8 8 0 0 8 8 8 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXX82541.1 - 6.6e-11 42.1 1.2 0.38 10.3 0.0 5.9 5 0 0 5 5 5 2 AAA domain IstB_IS21 PF01695.17 KXX82541.1 - 7.3e-11 42.1 0.1 0.23 11.2 0.0 6.3 6 0 0 6 6 6 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KXX82541.1 - 1.2e-09 38.4 0.0 0.19 11.6 0.0 6.5 6 0 0 6 6 5 1 ATPase domain predominantly from Archaea SRP54 PF00448.22 KXX82541.1 - 1.8e-09 37.5 3.4 1.1 8.9 0.0 6.5 7 0 0 7 7 6 3 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KXX82541.1 - 2.5e-09 37.6 4.5 1.5 9.0 0.0 6.9 6 0 0 6 6 6 1 AAA domain Rad17 PF03215.15 KXX82541.1 - 9.9e-09 35.4 3.8 0.19 11.7 0.0 6.8 7 0 0 7 7 7 1 Rad17 P-loop domain CbiA PF01656.23 KXX82541.1 - 2.1e-08 34.3 0.1 0.24 11.4 0.0 5.5 5 0 0 5 5 5 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KXX82541.1 - 7.9e-08 32.3 0.1 10 5.8 0.0 7.0 7 0 0 7 7 7 0 AAA domain TniB PF05621.11 KXX82541.1 - 9.4e-08 31.7 0.1 0.91 8.9 0.0 6.0 6 0 0 6 6 6 2 Bacterial TniB protein DUF815 PF05673.13 KXX82541.1 - 3e-07 29.9 3.8 1.1 8.4 0.0 5.5 6 0 0 6 6 5 2 Protein of unknown function (DUF815) Roc PF08477.13 KXX82541.1 - 4.1e-07 30.2 3.3 11 6.3 0.0 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 KXX82541.1 - 5.1e-07 30.1 6.2 4.5 7.6 0.1 6.2 6 0 0 6 6 5 0 AAA domain NTPase_1 PF03266.15 KXX82541.1 - 6.7e-07 29.4 4.7 1.6 8.6 0.0 5.8 5 0 0 5 5 5 2 NTPase ResIII PF04851.15 KXX82541.1 - 1e-06 28.9 0.1 2.1 8.3 0.0 6.2 6 0 0 6 6 6 1 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 KXX82541.1 - 2.9e-06 27.1 4.8 0.064 13.0 0.0 5.2 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KXX82541.1 - 1.1e-05 25.5 2.7 11 6.2 0.0 6.2 6 0 0 6 6 6 0 50S ribosome-binding GTPase dNK PF01712.19 KXX82541.1 - 1.3e-05 25.2 3.4 1.8 8.4 0.0 5.3 5 0 0 5 5 5 1 Deoxynucleoside kinase Viral_helicase1 PF01443.18 KXX82541.1 - 1.9e-05 24.5 0.1 4.7 6.9 0.0 4.8 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 KXX82541.1 - 2.4e-05 24.3 0.7 5.1 6.9 0.0 5.3 5 0 0 5 5 5 0 Bacterial dnaA protein NB-ARC PF00931.22 KXX82541.1 - 6.6e-05 22.2 3.5 14 4.8 0.0 6.1 6 0 0 6 6 6 0 NB-ARC domain DAP3 PF10236.9 KXX82541.1 - 0.00011 21.5 0.8 0.25 10.5 0.0 4.3 4 0 0 4 4 4 1 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.17 KXX82541.1 - 0.00011 22.0 3.3 3.1 7.5 0.0 5.6 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein TIP49 PF06068.13 KXX82541.1 - 0.00022 20.6 0.4 4.5 6.4 0.0 4.6 5 0 0 5 5 5 0 TIP49 P-loop domain cobW PF02492.19 KXX82541.1 - 0.00033 20.3 7.4 7.6 6.1 0.0 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 KXX82541.1 - 0.0018 17.8 0.1 17 4.8 0.0 4.7 5 0 0 5 5 4 0 PhoH-like protein KAP_NTPase PF07693.14 KXX82541.1 - 0.0024 17.2 0.0 30 3.7 0.0 5.1 4 1 0 4 4 4 0 KAP family P-loop domain SRPRB PF09439.10 KXX82541.1 - 0.0037 16.7 1.7 44 3.4 0.0 5.5 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit CPT PF07931.12 KXX82541.1 - 0.0045 16.8 0.1 38 4.1 0.0 5.0 3 1 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KXX82541.1 - 0.0047 16.3 0.0 6.1 6.1 0.0 4.2 3 0 0 3 3 3 0 KaiC VWA_2 PF13519.6 KXX82541.1 - 0.0068 17.0 0.3 0.069 13.8 0.1 3.0 2 0 0 2 2 1 1 von Willebrand factor type A domain APS_kinase PF01583.20 KXX82541.1 - 0.0071 16.3 0.5 0.7 9.8 0.0 4.1 5 0 0 5 5 4 1 Adenylylsulphate kinase MobB PF03205.14 KXX82541.1 - 0.01 15.8 6.0 25 4.8 0.1 5.5 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.29 KXX82541.1 - 0.022 14.6 0.3 9.9 5.9 0.0 4.1 5 0 0 5 5 3 0 DEAD/DEAH box helicase Ploopntkinase3 PF18751.1 KXX82541.1 - 0.04 13.8 0.2 26 4.6 0.0 4.3 5 0 0 5 5 4 0 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 KXX82541.1 - 0.043 13.5 8.2 22 4.6 0.0 5.9 7 0 0 7 7 5 0 Thymidylate kinase AAA_8 PF12780.7 KXX82541.1 - 0.059 12.7 0.7 20 4.4 0.0 4.3 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KXX82541.1 - 0.062 12.4 0.0 5.6 6.0 0.0 3.9 4 0 0 4 4 4 0 ATP-binding dynein motor region MeaB PF03308.16 KXX82541.1 - 0.089 11.8 1.7 7.5 5.4 0.1 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 KXX82541.1 - 0.14 11.4 1.4 17 4.6 0.0 4.0 5 0 0 5 5 3 0 Septin Ras PF00071.22 KXX82541.1 - 0.84 9.2 2.7 1.3e+02 2.1 0.0 4.5 5 0 0 5 5 5 0 Ras family DUF87 PF01935.17 KXX82541.1 - 3.9 7.5 8.4 3.1e+02 1.3 0.0 5.4 5 1 0 5 5 3 0 Helicase HerA, central domain Ribosomal_L12 PF00542.19 KXX82542.1 - 1.5e-20 73.3 6.6 1.2e-19 70.5 4.3 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KXX82542.1 - 1.4e-11 43.9 17.1 1e-10 41.1 14.5 2.8 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Hat1_N PF10394.9 KXX82543.1 - 1.4e-49 168.4 0.0 2.5e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Elong-fact-P_C PF09285.11 KXX82543.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Elongation factor P, C-terminal Acetyltransf_10 PF13673.7 KXX82543.1 - 0.08 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zip PF02535.22 KXX82544.1 - 1.3e-37 129.8 12.3 3.3e-25 89.0 9.4 2.0 1 1 0 2 2 2 2 ZIP Zinc transporter Het-C PF07217.11 KXX82545.1 - 4.5e-286 949.8 0.0 5.5e-286 949.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cyt-b5 PF00173.28 KXX82546.1 - 3.9e-18 65.4 0.8 1.3e-17 63.7 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KXX82546.1 - 1.2e-12 48.3 18.5 1.2e-12 48.3 18.5 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KXX82546.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Fungal_trans PF04082.18 KXX82547.1 - 2.7e-10 39.8 3.2 2.5e-07 30.0 0.0 3.7 4 0 0 4 4 4 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82547.1 - 7.2e-07 29.2 11.5 1.3e-06 28.5 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 KXX82548.1 - 0.065 13.5 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 BTB/POZ domain Dynactin PF12455.8 KXX82549.1 - 2.3e-115 384.8 8.8 2.3e-115 384.8 8.8 3.6 5 0 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 KXX82549.1 - 1e-24 86.3 0.7 1.9e-24 85.4 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 KXX82549.1 - 0.00029 20.3 24.0 0.00029 20.3 24.0 4.6 4 1 0 5 5 5 2 Uncharacterized coiled-coil protein (DUF2353) SRP19 PF01922.17 KXX82550.1 - 6.1e-33 113.6 0.0 1.1e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein SWI-SNF_Ssr4 PF08549.10 KXX82550.1 - 0.061 12.0 3.3 0.08 11.6 3.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) CCDC53 PF10152.9 KXX82550.1 - 0.58 10.6 4.7 0.86 10.0 4.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 KXX82550.1 - 1.3 8.5 6.8 1.8 8.1 6.8 1.1 1 0 0 1 1 1 0 Spt20 family CDP-OH_P_transf PF01066.21 KXX82551.1 - 1.5e-12 48.1 0.2 1.5e-12 48.1 0.2 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.24 KXX82552.1 - 3.3e-99 331.1 0.1 4.8e-99 330.5 0.1 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Dak2 PF02734.17 KXX82552.1 - 0.098 12.5 3.6 0.17 11.8 3.6 1.5 1 0 0 1 1 1 0 DAK2 domain TIP49 PF06068.13 KXX82554.1 - 8.9e-166 551.4 0.0 1.1e-165 551.0 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXX82554.1 - 1.2e-25 89.5 0.4 3.5e-25 87.9 0.2 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KXX82554.1 - 1.3e-11 45.1 0.1 5.9e-07 30.0 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX82554.1 - 5.8e-10 39.1 0.1 2.4e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXX82554.1 - 0.00031 21.0 0.2 0.37 11.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXX82554.1 - 0.00078 19.9 0.0 0.0061 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KXX82554.1 - 0.0027 18.0 0.5 0.0098 16.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXX82554.1 - 0.0047 16.5 0.1 0.038 13.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXX82554.1 - 0.0055 16.7 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KXX82554.1 - 0.0066 16.8 3.5 0.15 12.4 3.5 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXX82554.1 - 0.0081 15.6 0.1 0.31 10.4 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 KXX82554.1 - 0.023 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 KXX82554.1 - 0.025 14.3 0.1 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KXX82554.1 - 0.026 13.8 0.2 0.065 12.5 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 KXX82554.1 - 0.03 14.0 0.1 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 KXX82554.1 - 0.042 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXX82554.1 - 0.054 12.7 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KXX82554.1 - 0.077 12.5 0.1 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KXX82554.1 - 0.11 12.2 0.3 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain HMG_box PF00505.19 KXX82555.1 - 4.6e-23 81.4 2.6 7.7e-23 80.7 2.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXX82555.1 - 4.9e-09 36.7 2.5 1e-08 35.6 2.5 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KXX82555.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box zf-H2C2_2 PF13465.6 KXX82555.1 - 4.9 7.8 5.5 0.55 10.8 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger double domain VIR_N PF15912.5 KXX82556.1 - 0.45 10.1 5.3 0.6 9.7 5.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal SNF2_N PF00176.23 KXX82557.1 - 1e-73 248.1 0.8 1e-73 248.1 0.8 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX82557.1 - 2.2e-20 73.1 0.2 5e-18 65.5 0.0 3.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KXX82557.1 - 4.4e-19 68.3 0.0 1.2e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 KXX82557.1 - 1.1e-18 67.3 10.6 1.1e-18 67.3 10.6 5.3 5 1 1 6 6 6 1 HSA SnAC PF14619.6 KXX82557.1 - 2.4e-13 50.5 0.1 2.4e-13 50.5 0.1 4.6 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KXX82557.1 - 1.1e-10 41.1 1.6 4.4e-10 39.1 1.6 2.2 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KXX82557.1 - 1.5e-10 41.4 0.0 1.5e-10 41.4 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CorA PF01544.18 KXX82557.1 - 9.3 5.5 10.2 25 4.0 10.2 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein LRR_4 PF12799.7 KXX82559.1 - 8.2e-28 96.0 34.3 1.8e-05 25.0 2.2 8.8 6 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXX82559.1 - 2.6e-19 68.7 35.6 5.9e-06 25.9 4.4 6.9 6 1 2 8 8 8 5 Leucine rich repeat LRR_9 PF14580.6 KXX82559.1 - 4.7e-12 45.8 7.9 9.2e-06 25.3 2.2 3.8 2 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KXX82559.1 - 8.3 6.7 28.8 17 5.8 0.2 8.1 8 0 0 8 8 8 0 Leucine Rich repeat VWA PF00092.28 KXX82560.1 - 6.4e-08 33.0 0.0 9.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXX82560.1 - 0.00047 20.8 0.0 0.00085 19.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Cytidylate_kin PF02224.18 KXX82560.1 - 0.17 11.6 0.1 0.26 11.0 0.1 1.2 1 0 0 1 1 1 0 Cytidylate kinase Aminotran_1_2 PF00155.21 KXX82561.1 - 8.8e-39 133.7 0.0 1e-38 133.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glycos_transf_1 PF00534.20 KXX82562.1 - 3.4e-34 117.8 0.0 4.5e-32 110.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXX82562.1 - 1e-16 61.4 0.1 2.1e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXX82562.1 - 1.7e-14 54.4 0.3 4.1e-14 53.2 0.3 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXX82562.1 - 2.2e-07 31.5 0.2 2.2e-07 31.5 0.2 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXX82562.1 - 1.3e-06 28.7 0.0 6.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 ALG11_N PF15924.5 KXX82562.1 - 0.00071 19.7 1.4 1.3 9.0 0.2 3.0 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_4_5 PF16994.5 KXX82562.1 - 0.12 12.0 0.0 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl-transferase family 4 Pkinase PF00069.25 KXX82563.1 - 2.8e-50 171.1 0.0 4.5e-34 118.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX82563.1 - 7.3e-21 74.6 0.2 4.3e-19 68.8 0.2 3.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX82563.1 - 7.2e-05 22.2 0.0 0.00022 20.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXX82563.1 - 0.00079 19.4 0.1 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXX82563.1 - 0.0021 16.9 0.1 0.011 14.5 0.1 2.2 1 1 0 1 1 1 1 Fungal protein kinase DUF4698 PF15769.5 KXX82563.1 - 0.06 12.4 0.3 0.13 11.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) TFIIF_alpha PF05793.12 KXX82563.1 - 0.84 8.2 6.0 1.8 7.1 6.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CFEM PF05730.11 KXX82564.1 - 1.2e-11 44.5 4.6 2.2e-11 43.7 4.6 1.3 1 0 0 1 1 1 1 CFEM domain Endonuclease_NS PF01223.23 KXX82565.1 - 1e-66 225.0 0.0 1.4e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Patatin PF01734.22 KXX82565.1 - 0.019 15.2 1.4 0.051 13.8 1.4 1.7 1 1 0 1 1 1 0 Patatin-like phospholipase WD40 PF00400.32 KXX82567.1 - 1.3e-15 57.5 6.7 0.0018 19.1 0.5 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX82567.1 - 0.00027 21.2 0.0 9 6.7 0.0 4.2 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 KXX82567.1 - 0.0029 16.3 3.7 0.015 14.0 1.8 2.0 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) F-protein PF00469.20 KXX82567.1 - 0.14 11.8 0.6 0.25 10.9 0.6 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef FAM176 PF14851.6 KXX82567.1 - 0.2 11.3 0.5 0.4 10.3 0.5 1.5 1 0 0 1 1 1 0 FAM176 family DSBA PF01323.20 KXX82568.1 - 8.7e-17 61.5 0.0 4.1e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain BCNT PF07572.12 KXX82569.1 - 5.9e-24 83.9 0.6 1.2e-23 83.0 0.6 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development Zn_clus PF00172.18 KXX82570.1 - 3.2e-06 27.2 11.1 5.8e-06 26.3 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_A_M PF01068.21 KXX82571.1 - 9.4e-60 201.7 1.5 1.3e-57 194.8 1.5 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXX82571.1 - 4e-45 154.2 0.0 9.3e-45 153.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXX82571.1 - 7.5e-29 100.2 0.6 2.8e-28 98.4 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXX82571.1 - 1.4e-05 25.5 0.4 2.3e-05 24.8 0.4 1.4 1 0 0 1 1 1 1 RNA ligase PNKP_ligase PF16542.5 KXX82571.1 - 0.04 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain E1_dh PF00676.20 KXX82572.1 - 6.6e-113 376.6 0.1 8.6e-113 376.2 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXX82572.1 - 0.0018 17.6 0.1 0.0031 16.8 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.32 KXX82573.1 - 3e-37 125.9 25.5 1.8e-07 31.7 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KXX82573.1 - 2.9e-12 46.3 0.9 5.5e-12 45.4 0.9 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXX82573.1 - 1.1e-08 35.3 3.6 0.53 10.6 0.0 6.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX82573.1 - 1e-06 27.8 9.4 0.13 10.9 0.1 5.6 1 1 5 6 6 6 3 Nucleoporin Nup120/160 F-box PF00646.33 KXX82573.1 - 9e-06 25.4 2.3 1.7e-05 24.6 2.3 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 KXX82573.1 - 0.0033 17.0 6.9 0.48 10.0 0.1 3.8 1 1 3 4 4 4 2 PQQ-like domain WD40_like PF17005.5 KXX82573.1 - 0.015 14.7 0.0 1.1 8.5 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 KXX82573.1 - 0.12 12.9 1.9 9.2 6.9 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain CAP_N PF01213.19 KXX82573.1 - 1.5 8.3 2.8 2.6 7.4 2.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ERCC3_RAD25_C PF16203.5 KXX82574.1 - 1.2e-120 401.4 0.1 2.2e-120 400.5 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KXX82574.1 - 9.8e-33 113.0 0.0 3.9e-32 111.1 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX82574.1 - 4.1e-18 66.0 0.0 9e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXX82574.1 - 6.3e-12 45.8 0.1 1.9e-11 44.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXX82574.1 - 2.2e-08 33.3 0.0 2.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KXX82574.1 - 0.00047 20.0 0.0 0.0043 16.8 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase MraY_sig1 PF10555.9 KXX82574.1 - 0.47 10.1 1.8 1.5 8.5 1.8 1.9 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 zf-CHY PF05495.12 KXX82575.1 - 3.4e-07 30.6 9.9 6.8e-07 29.7 9.9 1.5 1 0 0 1 1 1 1 CHY zinc finger Zn_ribbon_SprT PF17283.2 KXX82575.1 - 0.11 12.4 5.2 0.72 9.8 1.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HypA PF01155.19 KXX82575.1 - 0.78 9.8 9.7 2.7 8.1 9.7 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KXX82575.1 - 2.1 8.6 11.1 0.64 10.3 6.0 2.5 1 1 2 3 3 3 0 zinc-ribbon Proteasome PF00227.26 KXX82576.1 - 4.8e-57 192.5 0.1 8.1e-57 191.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXX82576.1 - 1.1e-11 44.1 0.4 3.6e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.19 KXX82577.1 - 1.3e-65 221.6 0.0 1.7e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXX82577.1 - 1e-36 125.7 0.6 1.9e-36 124.9 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_11 PF00457.17 KXX82578.1 - 3.6e-79 264.5 22.6 4.2e-79 264.3 22.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 TrkH PF02386.16 KXX82579.1 - 6.3e-143 476.8 15.3 8.8e-142 473.1 7.1 2.0 2 0 0 2 2 2 2 Cation transport protein Ribosomal_S4e PF00900.20 KXX82580.1 - 7.7e-37 125.1 0.2 1.8e-36 123.9 0.2 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KXX82580.1 - 2.7e-23 81.4 0.1 4.3e-23 80.7 0.1 1.3 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KXX82580.1 - 4.3e-19 68.3 5.3 8.6e-19 67.4 5.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KXX82580.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KXX82580.1 - 0.00014 21.7 1.8 0.00014 21.7 1.8 3.1 3 0 0 3 3 3 1 KOW motif LysM PF01476.20 KXX82582.1 - 3.6e-07 30.1 0.0 7.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain Myb_DNA-binding PF00249.31 KXX82583.1 - 1.7e-18 66.5 0.2 3.9e-10 39.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXX82583.1 - 2.8e-11 43.5 0.1 0.00011 22.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KXX82583.1 - 1.2e-05 25.3 1.3 0.036 14.1 0.0 2.9 3 0 0 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 KXX82583.1 - 0.00082 19.5 0.0 0.0032 17.6 0.0 1.8 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Mid2 PF04478.12 KXX82585.1 - 0.0054 16.6 1.9 0.021 14.7 1.9 2.0 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor SPX PF03105.19 KXX82585.1 - 0.077 12.9 8.6 0.095 12.6 8.6 1.2 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 KXX82585.1 - 0.53 8.9 3.8 0.64 8.6 3.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KXX82585.1 - 6.4 5.5 7.8 7.5 5.3 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAM2 PF07145.15 KXX82586.1 - 0.00014 21.3 10.0 0.14 11.9 0.5 5.0 5 0 0 5 5 5 3 Ataxin-2 C-terminal region Exo_endo_phos PF03372.23 KXX82587.1 - 4.4e-14 52.6 0.0 8e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KXX82587.1 - 2.8e-06 27.3 0.5 6.9e-06 26.1 0.5 1.7 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.19 KXX82589.1 - 5e-22 78.1 0.3 1.1e-21 77.0 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXX82589.1 - 8.5e-07 29.5 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain ANTH PF07651.16 KXX82590.1 - 6.1e-81 271.5 0.0 6.1e-81 271.5 0.0 2.4 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KXX82590.1 - 4.5e-55 186.1 10.4 4.5e-55 186.1 10.4 6.6 4 2 4 9 9 9 2 I/LWEQ domain T2SSF PF00482.23 KXX82590.1 - 0.76 9.7 5.4 1.2 9.1 1.7 3.4 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F Autophagy_N PF03986.13 KXX82591.1 - 5.6e-44 149.4 0.2 1.2e-43 148.4 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KXX82591.1 - 9.9e-16 57.0 0.5 2.2e-15 55.8 0.5 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KXX82591.1 - 5.1e-15 55.8 0.2 1.1e-14 54.7 0.2 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain zf-CCCH PF00642.24 KXX82592.1 - 1.6e-08 34.2 2.3 3.4e-08 33.2 2.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KXX82592.1 - 3.9e-07 29.8 3.4 6.9e-07 29.0 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX82592.1 - 3.8e-06 26.7 5.9 6.8e-06 25.9 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX82592.1 - 5.4e-06 26.1 5.4 1e-05 25.3 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KXX82592.1 - 3.7e-05 23.8 1.9 8.1e-05 22.7 1.9 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KXX82592.1 - 4e-05 23.6 7.1 7.6e-05 22.7 7.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KXX82592.1 - 5.8e-05 23.0 6.8 0.0001 22.2 6.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-RING_5 PF14634.6 KXX82592.1 - 0.00011 22.1 6.0 0.0002 21.3 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH_4 PF18044.1 KXX82592.1 - 0.00038 20.2 3.2 0.00038 20.2 3.2 1.8 2 0 0 2 2 1 1 CCCH-type zinc finger zf-RING_2 PF13639.6 KXX82592.1 - 0.00053 20.3 4.8 0.00097 19.4 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXX82592.1 - 0.0072 16.2 4.2 0.013 15.3 4.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXX82592.1 - 0.083 13.1 6.8 0.18 12.0 6.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KXX82592.1 - 0.2 12.2 4.7 0.36 11.4 4.7 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Harakiri PF15196.6 KXX82592.1 - 0.59 10.6 3.4 0.51 10.8 1.4 1.9 2 0 0 2 2 2 0 Activator of apoptosis harakiri TRP PF06011.12 KXX82593.1 - 7e-102 341.3 19.9 9.1e-102 340.9 19.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXX82593.1 - 3.2e-33 115.0 0.0 5.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 ML-like domain COX6A PF02046.15 KXX82595.1 - 1e-50 170.9 0.7 1.2e-50 170.6 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANAPC5 PF12862.7 KXX82596.1 - 1.2e-30 105.4 1.6 4e-30 103.7 1.6 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KXX82596.1 - 0.00066 19.9 14.6 6.6 7.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 KXX82596.1 - 0.0015 18.3 0.1 0.062 13.0 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 KXX82596.1 - 0.017 15.1 4.7 6.1 7.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX82596.1 - 0.021 14.7 10.0 3.4 7.7 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXX82596.1 - 0.034 14.3 10.2 42 4.6 0.4 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX82596.1 - 0.22 11.8 3.4 95 3.6 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXX82596.1 - 0.25 11.2 6.2 19 5.2 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXX82596.1 - 0.46 11.2 14.6 8.1 7.2 2.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXX82596.1 - 1.3 10.0 17.1 2.8 9.0 0.9 6.3 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXX82596.1 - 2.7 8.6 16.6 0.36 11.4 0.6 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat PA PF02225.22 KXX82597.1 - 9.7e-11 41.6 0.0 2.6e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-RING_11 PF17123.5 KXX82597.1 - 1.1e-07 31.5 2.0 1.8e-07 30.7 2.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXX82597.1 - 1.3e-05 25.4 1.7 2e-05 24.8 1.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX82597.1 - 0.00047 19.9 1.5 0.00074 19.3 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX82597.1 - 0.00096 19.0 0.7 0.0015 18.4 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX82597.1 - 0.0032 17.4 1.3 0.006 16.6 1.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXX82597.1 - 0.021 14.7 0.8 0.033 14.2 0.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KXX82597.1 - 0.26 11.6 0.5 0.46 10.8 0.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain tRNA-synt_1 PF00133.22 KXX82598.1 - 1.5e-228 760.0 0.0 2.9e-227 755.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXX82598.1 - 6.8e-35 120.3 0.0 1.9e-34 118.8 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXX82598.1 - 1.3e-14 53.8 0.5 0.00019 20.3 0.1 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KXX82598.1 - 6.1e-11 42.2 0.1 1.8e-07 30.8 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KXX82598.1 - 0.00066 19.1 0.0 0.02 14.2 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Ribosomal_L37e PF01907.19 KXX82599.1 - 2.1e-27 95.0 11.4 3e-27 94.5 11.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KXX82599.1 - 0.0079 16.2 0.9 0.011 15.7 0.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2845 PF11006.8 KXX82599.1 - 0.052 13.7 0.2 0.072 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) HypA PF01155.19 KXX82599.1 - 0.067 13.2 0.7 0.091 12.8 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KXX82599.1 - 0.12 11.8 1.4 0.21 11.0 1.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KXX82599.1 - 0.14 11.9 3.0 7.3 6.4 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C3HC4_2 PF13923.6 KXX82599.1 - 0.32 10.9 3.3 0.55 10.1 3.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXX82599.1 - 0.42 10.5 3.7 0.7 9.8 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1289 PF06945.13 KXX82599.1 - 1.7 8.5 7.7 0.91 9.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) ELP6 PF09807.9 KXX82600.1 - 2.9e-06 26.9 0.1 4.6e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 Elongation complex protein 6 Serglycin PF04360.12 KXX82600.1 - 0.4 10.6 1.4 30 4.5 1.6 2.5 3 0 0 3 3 3 0 Serglycin MFS_1 PF07690.16 KXX82601.1 - 2.1e-39 135.4 34.1 2.8e-28 98.9 15.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX82601.1 - 6.1e-12 45.1 11.4 6.1e-12 45.1 11.4 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Thioredoxin PF00085.20 KXX82602.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KXX82602.1 - 0.017 14.8 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.6 KXX82602.1 - 0.037 14.5 0.0 0.45 11.0 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain BLOC1_2 PF10046.9 KXX82603.1 - 3.7e-05 24.0 0.2 0.0091 16.3 0.1 2.7 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KXX82603.1 - 7.4e-05 21.8 9.5 0.033 13.1 0.6 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 KXX82603.1 - 0.0027 17.9 15.0 0.057 13.7 0.4 4.5 3 1 1 4 4 4 2 ABC transporter C-terminal domain KxDL PF10241.9 KXX82603.1 - 0.015 15.5 0.4 0.076 13.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Atg14 PF10186.9 KXX82603.1 - 0.023 13.8 7.9 0.86 8.6 3.4 2.4 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PuR_N PF09182.10 KXX82603.1 - 0.025 14.5 0.0 3.9 7.5 0.0 2.9 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal Fez1 PF06818.15 KXX82603.1 - 0.063 13.7 8.5 0.022 15.2 5.5 1.7 2 0 0 2 2 2 0 Fez1 APG6_N PF17675.1 KXX82603.1 - 0.09 13.3 7.6 3.2 8.3 2.9 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Prefoldin PF02996.17 KXX82603.1 - 0.093 12.7 0.3 10 6.1 0.1 2.8 3 0 0 3 3 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 KXX82603.1 - 0.14 12.2 8.0 1.5 8.8 3.6 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 KXX82603.1 - 0.17 12.5 11.8 0.12 13.0 1.7 3.8 4 1 1 5 5 4 0 SlyX DUF4407 PF14362.6 KXX82603.1 - 0.18 11.1 14.6 0.48 9.7 14.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KXX82603.1 - 0.23 10.0 5.5 0.059 12.0 1.3 1.9 1 1 1 2 2 2 0 AAA domain Csm1_N PF18504.1 KXX82603.1 - 0.29 11.5 10.2 36 4.8 0.4 4.4 2 2 2 4 4 4 0 Csm1 N-terminal domain Uso1_p115_C PF04871.13 KXX82603.1 - 0.35 11.2 9.9 4.4 7.7 0.2 2.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Macoilin PF09726.9 KXX82603.1 - 0.4 9.2 5.2 0.7 8.4 5.2 1.4 1 1 0 1 1 1 0 Macoilin family DivIC PF04977.15 KXX82603.1 - 0.41 10.4 14.0 14 5.5 0.1 3.7 2 1 0 3 3 3 0 Septum formation initiator OmpH PF03938.14 KXX82603.1 - 0.57 10.5 10.7 1.3 9.4 0.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) YlqD PF11068.8 KXX82603.1 - 0.68 10.3 3.2 1.8 8.9 1.2 2.2 2 0 0 2 2 2 0 YlqD protein Cluap1 PF10234.9 KXX82603.1 - 0.78 9.1 4.7 11 5.3 0.2 2.3 2 1 0 2 2 2 0 Clusterin-associated protein-1 TMF_TATA_bd PF12325.8 KXX82603.1 - 0.87 9.8 6.5 4.4 7.6 1.7 3.0 3 1 0 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF2721 PF11026.8 KXX82603.1 - 1.2 9.0 3.7 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Spc24 PF08286.11 KXX82603.1 - 1.4 9.2 8.3 0.67 10.2 0.8 3.3 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 zf-C2H2_4 PF13894.6 KXX82604.1 - 0.16 12.9 0.4 10 7.2 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger bZIP_1 PF00170.21 KXX82605.1 - 7.1e-08 32.4 16.5 1.1e-07 31.9 16.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KXX82605.1 - 0.00012 21.9 7.9 0.00038 20.3 0.0 2.1 1 1 1 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 KXX82605.1 - 0.00065 19.5 8.2 0.00093 19.0 8.2 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Adaptin_binding PF10199.9 KXX82605.1 - 0.00069 20.2 1.5 0.00093 19.8 1.5 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 V_ATPase_I PF01496.19 KXX82605.1 - 0.0062 14.5 2.0 0.0076 14.2 2.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ADIP PF11559.8 KXX82605.1 - 0.034 14.2 11.2 2.5 8.2 12.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KXX82605.1 - 0.037 14.7 0.4 0.069 13.8 0.4 1.4 1 0 0 1 1 1 0 Initiation control protein YabA GIT_CC PF16559.5 KXX82605.1 - 0.058 13.3 4.5 0.1 12.5 4.5 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor GvpL_GvpF PF06386.11 KXX82605.1 - 0.079 12.9 5.0 0.12 12.2 5.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 KXX82605.1 - 0.082 13.0 19.1 0.31 11.2 17.3 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 KXX82605.1 - 0.12 12.9 17.2 0.43 11.1 17.4 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor FapA PF03961.13 KXX82605.1 - 0.19 10.3 0.9 0.26 9.8 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PSI_PsaF PF02507.15 KXX82605.1 - 0.21 11.4 0.6 0.92 9.3 1.1 1.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III SVIP PF15811.5 KXX82605.1 - 1 9.8 16.1 1.5 9.4 14.7 1.9 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DUF3499 PF12005.8 KXX82605.1 - 1.2 9.7 4.6 0.48 11.0 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3499) XhlA PF10779.9 KXX82605.1 - 1.8 8.8 4.1 3.2 8.0 4.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA OmpH PF03938.14 KXX82605.1 - 2.2 8.6 12.3 3.7 7.9 12.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KXX82605.1 - 3.7 6.3 11.1 5.4 5.8 11.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 KXX82605.1 - 4 4.8 13.1 5.1 4.5 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EMP24_GP25L PF01105.24 KXX82605.1 - 5.6 6.9 5.2 8.8 6.2 5.2 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Tho2 PF11262.8 KXX82605.1 - 9.7 5.3 7.4 14 4.8 7.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Septin PF00735.18 KXX82607.1 - 6.4e-32 110.9 0.0 3.2e-11 43.0 0.0 3.2 3 0 0 3 3 3 3 Septin G-alpha PF00503.20 KXX82607.1 - 0.012 14.8 0.0 0.038 13.2 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.6 KXX82607.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KXX82607.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KXX82607.1 - 0.026 15.0 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KXX82607.1 - 0.05 13.1 0.0 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX82607.1 - 0.057 13.5 0.3 0.28 11.3 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXX82607.1 - 0.068 13.2 0.8 0.58 10.2 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KXX82607.1 - 0.081 13.5 0.0 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KXX82607.1 - 0.23 10.9 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein PLATZ PF04640.14 KXX82608.1 - 0.005 17.4 3.2 0.005 17.4 3.2 3.7 3 1 0 3 3 3 1 PLATZ transcription factor zf-MYND PF01753.18 KXX82608.1 - 0.0065 16.5 15.4 0.053 13.6 0.8 3.2 3 0 0 3 3 3 2 MYND finger zf-C6H2 PF15801.5 KXX82608.1 - 0.021 15.1 16.9 1.1 9.6 1.1 3.8 3 1 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding TerY_C PF15616.6 KXX82608.1 - 0.27 11.3 4.2 6.5 6.9 0.1 2.4 2 0 0 2 2 2 0 TerY-C metal binding domain AP1AR PF15745.5 KXX82608.1 - 4.2 6.9 7.6 1.5 8.4 1.1 2.2 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein SUR7 PF06687.12 KXX82609.1 - 8.3e-25 87.7 14.4 1.1e-24 87.2 14.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4381 PF14316.6 KXX82609.1 - 1.5 9.1 3.1 0.87 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) ABC1 PF03109.16 KXX82610.1 - 1.3e-21 77.0 0.0 3.2e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KXX82610.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family 2OG-FeII_Oxy_3 PF13640.6 KXX82611.1 - 5.5e-10 40.0 0.0 1e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD-oxidase_C PF02913.19 KXX82612.1 - 8.4e-62 209.0 0.0 2.8e-61 207.3 0.0 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXX82612.1 - 3e-34 117.7 0.0 5.6e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KXX82612.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS SF3b10 PF07189.11 KXX82613.1 - 1.5e-37 127.6 0.0 1.7e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 KXX82614.1 - 2.5e-69 233.2 0.0 3.5e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 MAGE family MCM6_C PF18263.1 KXX82614.1 - 0.028 14.6 0.2 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain GFRP PF06399.13 KXX82614.1 - 0.033 14.1 0.1 0.092 12.6 0.0 1.8 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) SUI1 PF01253.22 KXX82615.1 - 1.7e-26 92.5 1.4 2.3e-26 92.1 1.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.8 KXX82615.1 - 0.097 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) EOS1 PF12326.8 KXX82616.1 - 5.3e-18 65.6 9.1 1.4e-17 64.2 5.0 2.3 1 1 1 2 2 2 2 N-glycosylation protein Dioxygenase_C PF00775.21 KXX82617.1 - 1.7e-43 148.2 0.0 2.3e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXX82617.1 - 1.1e-30 105.2 0.0 2.1e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXX82617.1 - 1.8e-05 24.9 0.0 5.5e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF824 PF05688.11 KXX82617.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Salmonella repeat of unknown function (DUF824) Big_1 PF02369.16 KXX82617.1 - 0.025 14.6 0.2 0.066 13.2 0.2 1.7 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) SpaA PF17802.1 KXX82617.1 - 0.077 13.3 0.0 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Prealbumin-like fold domain AdoMet_MTase PF07757.13 KXX82618.1 - 1.1e-36 125.5 0.0 2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KXX82618.1 - 0.032 14.2 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXX82618.1 - 0.035 13.9 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 KXX82619.1 - 3.5e-27 94.0 0.3 7.3e-14 51.4 0.1 3.5 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX82619.1 - 2.7e-05 24.2 0.1 0.0011 19.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif Tim44 PF04280.15 KXX82620.1 - 6.9e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain RHS_repeat PF05593.14 KXX82620.1 - 0.23 12.0 1.0 1 9.9 0.0 2.3 2 0 0 2 2 2 0 RHS Repeat SSF PF00474.17 KXX82621.1 - 1.9e-10 40.2 32.4 7.6e-10 38.2 32.4 1.9 1 1 0 1 1 1 1 Sodium:solute symporter family Adaptin_N PF01602.20 KXX82623.1 - 3.2e-117 392.2 0.6 4.1e-117 391.9 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KXX82623.1 - 5.4e-55 185.7 6.5 1.1e-54 184.7 6.5 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KXX82623.1 - 2.1e-35 121.3 0.3 5.8e-35 119.9 0.3 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KXX82623.1 - 3.9e-18 65.6 0.3 2.2e-12 47.2 0.0 5.5 2 1 3 5 5 5 1 HEAT repeats Cnd1 PF12717.7 KXX82623.1 - 8.1e-07 29.2 8.8 0.027 14.5 0.1 4.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KXX82623.1 - 0.00068 20.1 0.5 1.2 10.0 0.0 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat MRP-S35 PF10246.9 KXX82623.1 - 0.022 14.7 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 CLASP_N PF12348.8 KXX82623.1 - 0.03 13.9 5.7 0.036 13.6 0.1 3.0 3 1 0 4 4 4 0 CLASP N terminal RTP1_C1 PF10363.9 KXX82623.1 - 0.04 14.1 0.5 5.1 7.3 0.0 3.7 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Coatomer_b_Cpla PF14806.6 KXX82623.1 - 0.041 13.9 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform HEAT PF02985.22 KXX82623.1 - 0.088 13.1 6.7 2.1 8.8 0.2 4.9 5 0 0 5 5 4 0 HEAT repeat DUF5010 PF16402.5 KXX82623.1 - 0.14 10.9 0.0 0.31 9.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT_EZ PF13513.6 KXX82623.1 - 6.3 7.4 5.9 2.5 8.7 0.7 3.1 3 0 0 3 3 3 0 HEAT-like repeat CDP-OH_P_transf PF01066.21 KXX82624.1 - 1.8e-17 63.8 0.1 1.8e-17 63.8 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Lipase_3 PF01764.25 KXX82625.1 - 1.9e-15 57.0 0.0 2.8e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXX82625.1 - 4.2e-05 24.3 0.0 5.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXX82625.1 - 0.02 14.6 0.0 0.05 13.3 0.0 1.6 1 1 1 2 2 2 0 PGAP1-like protein UPF0016 PF01169.19 KXX82627.1 - 5.7e-43 145.1 22.7 9e-22 77.2 7.7 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-bind_6 PF13921.6 KXX82628.1 - 0.022 15.0 0.1 0.052 13.8 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain ATP-sulfurylase PF01747.17 KXX82629.1 - 1.5e-87 292.6 0.0 2.2e-87 292.0 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KXX82629.1 - 1.6e-57 193.8 0.0 2.6e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KXX82629.1 - 2.2e-53 180.2 0.0 3.8e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain EI24 PF07264.11 KXX82630.1 - 3.9e-11 43.5 2.3 6.2e-11 42.9 2.3 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Iron_permease PF04120.12 KXX82630.1 - 4.8 7.0 5.2 3.2 7.5 2.5 1.9 2 0 0 2 2 2 0 Low affinity iron permease CIA30 PF08547.12 KXX82631.1 - 8.3e-47 159.2 0.0 1.2e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) JmjC PF02373.22 KXX82632.1 - 2.2e-17 63.5 0.0 4.3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.28 KXX82632.1 - 0.00046 20.6 0.0 0.0013 19.2 0.0 1.6 1 1 0 1 1 1 1 SET domain Mcp5_PH PF12814.7 KXX82633.1 - 7.9e-46 155.1 0.1 1.6e-45 154.2 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KXX82633.1 - 1.6e-05 25.3 0.0 4.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Fez1 PF06818.15 KXX82633.1 - 1.4 9.3 42.4 0.038 14.4 19.1 3.7 4 0 0 4 4 4 0 Fez1 TPR_12 PF13424.6 KXX82634.1 - 2.1e-12 47.2 10.9 4.8e-06 26.8 0.1 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXX82634.1 - 1.4e-05 24.8 11.9 0.55 10.5 0.3 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXX82634.1 - 2.1e-05 24.2 15.8 0.00072 19.4 0.4 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXX82634.1 - 6.3e-05 22.9 5.7 0.68 10.3 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXX82634.1 - 0.002 17.9 4.4 0.27 11.1 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXX82634.1 - 0.0025 18.5 22.8 13 7.0 0.9 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXX82634.1 - 0.0064 17.0 15.0 0.01 16.3 2.3 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXX82634.1 - 0.31 10.8 2.7 10 5.9 0.4 3.7 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 KXX82634.1 - 0.35 11.0 6.6 13 6.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXX82634.1 - 5.5 7.7 26.2 0.41 11.3 0.7 5.3 3 2 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX82634.1 - 7.7 7.4 16.0 19 6.1 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 KXX82636.1 - 2.4e-29 101.7 1.8 1.1e-11 45.2 0.0 5.2 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX82636.1 - 1.2e-19 70.4 9.8 2.8e-05 24.6 0.2 7.2 5 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KXX82636.1 - 6e-18 64.4 8.6 0.00069 19.9 0.7 8.2 7 1 0 7 7 6 4 Ankyrin repeat Ank_3 PF13606.6 KXX82636.1 - 5.3e-14 51.0 6.4 0.032 14.8 0.0 8.5 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 KXX82636.1 - 2.4e-13 50.0 6.2 0.00077 19.7 0.4 6.0 3 3 2 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.12 KXX82636.1 - 9.1e-08 32.2 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXX82636.1 - 9.2e-06 26.1 0.2 4.8e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXX82636.1 - 0.022 15.2 0.0 0.089 13.2 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT_N PF17100.5 KXX82636.1 - 0.055 13.3 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase RNA_helicase PF00910.22 KXX82636.1 - 0.059 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KXX82636.1 - 0.063 13.2 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KXX82636.1 - 0.069 13.4 0.0 0.24 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain SspK PF08176.12 KXX82636.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein K family Mucin PF01456.17 KXX82638.1 - 0.44 10.5 7.7 1.6 8.7 7.7 1.9 1 1 0 1 1 1 0 Mucin-like glycoprotein NB-ARC PF00931.22 KXX82641.1 - 7.9e-19 67.8 0.0 1.3e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXX82641.1 - 3.4e-08 34.1 0.4 7.6e-07 29.7 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain Goodbye PF17109.5 KXX82641.1 - 8.4e-06 26.2 0.0 3.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 KXX82641.1 - 0.0046 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Dabb PF07876.12 KXX82643.1 - 2.7e-22 79.2 0.0 1.8e-20 73.3 0.0 2.0 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain PAPS_reduct PF01507.19 KXX82645.1 - 4.2e-20 72.5 0.0 2.1e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ADH_zinc_N_2 PF13602.6 KXX82647.1 - 4.9e-24 85.9 0.0 9.1e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX82647.1 - 2.4e-15 56.7 0.2 3.6e-15 56.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXX82647.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXX82647.1 - 0.011 15.2 0.5 0.018 14.5 0.5 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 KXX82647.1 - 0.13 12.4 0.2 0.2 11.8 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KXX82647.1 - 0.15 11.5 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NUDIX PF00293.28 KXX82648.1 - 8.6e-11 42.0 0.3 1.3e-10 41.5 0.3 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXX82648.1 - 0.055 13.4 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 NUDIX domain LDB19 PF13002.7 KXX82649.1 - 4.8e-34 117.7 0.3 7.4e-34 117.1 0.3 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KXX82649.1 - 5e-05 23.4 0.1 0.00014 21.9 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SQS_PSY PF00494.19 KXX82650.1 - 1.3e-65 221.5 0.0 3e-65 220.4 0.0 1.5 1 1 0 1 1 1 1 Squalene/phytoene synthase LIP PF03583.14 KXX82651.1 - 3.2e-49 167.8 0.0 4.4e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KXX82651.1 - 0.0031 17.0 0.3 0.27 10.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF3237 PF11578.8 KXX82652.1 - 9e-20 71.0 0.5 1.4e-15 57.4 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) SNF2_N PF00176.23 KXX82653.1 - 5.8e-74 248.9 0.0 8.8e-74 248.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXX82653.1 - 1.9e-26 91.8 0.0 3.3e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXX82653.1 - 6.7e-16 58.6 0.0 1.3e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX82653.1 - 4.1e-05 23.6 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KXX82653.1 - 0.00047 20.0 9.4 0.001 18.9 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXX82653.1 - 0.0014 18.4 6.4 0.0031 17.3 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXX82653.1 - 0.0036 17.6 10.3 0.0095 16.2 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain ERCC3_RAD25_C PF16203.5 KXX82653.1 - 0.005 16.1 1.9 0.0051 16.0 0.1 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_3 PF13920.6 KXX82653.1 - 0.015 15.2 8.5 0.031 14.1 8.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX82653.1 - 0.061 13.4 9.1 0.14 12.2 9.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KXX82653.1 - 2.4 8.2 8.8 6.4 6.8 8.8 1.8 1 0 0 1 1 1 0 zinc-RING finger domain IU_nuc_hydro PF01156.19 KXX82655.1 - 8.8e-13 48.5 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HET PF06985.11 KXX82656.1 - 3.6e-25 89.0 0.0 5.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_17 PF00332.18 KXX82657.1 - 8.2e-08 32.2 0.5 1.7e-07 31.1 0.4 1.5 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 PTCB-BRCT PF12738.7 KXX82659.1 - 9.7e-43 144.0 0.4 3.3e-22 78.2 0.0 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KXX82659.1 - 1.9e-34 117.9 0.2 9e-12 45.2 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXX82659.1 - 6.8e-16 58.4 0.1 3.9e-07 30.4 0.0 3.7 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXX82659.1 - 3.9e-08 33.5 0.7 0.0019 18.4 0.0 3.4 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KXX82659.1 - 0.0022 17.8 0.0 2.8 7.9 0.0 3.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KXX82659.1 - 0.0044 17.1 0.4 0.22 11.6 0.1 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Ndc1_Nup PF09531.10 KXX82659.1 - 0.042 12.5 7.0 0.077 11.7 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup K_channel_TID PF07941.11 KXX82659.1 - 4.8 7.7 24.8 0.074 13.5 4.3 3.5 3 1 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain AAA PF00004.29 KXX82662.1 - 2.9e-07 31.0 0.1 2.2e-06 28.1 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXX82662.1 - 5.2e-05 23.2 0.1 0.00091 19.2 0.0 2.7 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 KXX82662.1 - 0.00087 19.6 0.1 0.0032 17.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXX82662.1 - 0.006 17.0 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KXX82662.1 - 0.053 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KXX82662.1 - 0.094 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXX82662.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CDC45 PF02724.14 KXX82662.1 - 2 6.6 4.2 3.2 5.9 3.3 1.7 2 0 0 2 2 2 0 CDC45-like protein Asp PF00026.23 KXX82663.1 - 4.8e-57 193.8 0.0 5.9e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXX82663.1 - 3.2e-14 53.6 4.1 8.5e-13 48.9 1.4 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXX82663.1 - 0.023 15.4 0.1 9.7 6.9 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease HET PF06985.11 KXX82666.1 - 1.4e-21 77.3 0.0 3.8e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zip PF02535.22 KXX82667.1 - 3.6e-47 161.2 7.3 4.5e-47 160.9 7.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter AMP-binding PF00501.28 KXX82668.1 - 3.3e-55 187.4 0.0 4.5e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXX82668.1 - 9.4e-19 67.4 0.0 2.2e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KXX82668.1 - 0.066 14.2 0.3 0.16 13.0 0.3 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 KXX82669.1 - 2e-57 194.6 0.5 5.4e-57 193.3 0.5 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX82669.1 - 8.3e-50 169.2 0.0 2.4e-49 167.7 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXX82669.1 - 5.4e-43 147.7 0.8 9.5e-43 146.9 0.8 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXX82669.1 - 1.4e-36 126.3 0.0 2.7e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KXX82669.1 - 2.1e-33 114.8 0.2 5.4e-33 113.5 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXX82669.1 - 4.2e-18 65.9 0.0 1.2e-17 64.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXX82669.1 - 2.1e-12 46.9 0.0 5.6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KXX82669.1 - 3.4e-12 46.5 0.0 7.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXX82669.1 - 1.8e-11 44.1 0.0 2.3e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KXX82669.1 - 4e-11 43.5 0.0 4.6e-10 40.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KXX82669.1 - 2.1e-10 40.8 0.1 1.4e-09 38.2 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KXX82669.1 - 5.1e-09 37.3 0.0 2.1e-08 35.3 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KXX82669.1 - 1.6e-08 34.5 0.0 8.4e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82669.1 - 3.2e-07 30.9 0.0 1.2e-06 29.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXX82669.1 - 3e-06 27.0 0.0 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KXX82669.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 KXX82669.1 - 0.00021 21.1 1.2 0.00073 19.3 1.2 2.0 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 KXX82669.1 - 0.00086 19.7 0.4 4.3 7.8 0.0 3.5 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension Methyltransf_16 PF10294.9 KXX82669.1 - 0.0018 18.1 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase YbbR PF07949.12 KXX82669.1 - 0.013 15.8 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 YbbR-like protein Methyltransf_33 PF10017.9 KXX82669.1 - 0.021 14.0 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Thiolase_N PF00108.23 KXX82669.1 - 0.029 13.8 0.1 0.063 12.6 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain DREV PF05219.12 KXX82669.1 - 0.03 13.4 0.1 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase Ubie_methyltran PF01209.18 KXX82669.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 KXX82669.1 - 0.043 13.0 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 KXX82669.1 - 0.065 13.1 2.6 5.7 6.9 1.1 3.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Asp PF00026.23 KXX82671.1 - 0.00023 20.7 0.0 0.00028 20.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KXX82671.1 - 0.19 11.5 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal SNF2_N PF00176.23 KXX82672.1 - 8.6e-62 208.9 0.0 1.2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KXX82672.1 - 6.6e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KXX82672.1 - 0.00013 21.7 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-RING_5 PF14634.6 KXX82672.1 - 0.95 9.5 4.9 2.1 8.4 4.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain AAA_7 PF12775.7 KXX82673.1 - 0.003 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KXX82673.1 - 0.0033 17.8 6.4 0.0047 17.3 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain DUF2075 PF09848.9 KXX82673.1 - 0.0048 16.2 0.0 0.0098 15.2 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KXX82673.1 - 0.016 15.2 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXX82673.1 - 0.019 14.7 0.1 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXX82673.1 - 0.037 13.9 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KXX82673.1 - 0.11 12.9 0.0 0.73 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXX82673.1 - 0.12 12.1 0.1 1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXX82673.1 - 0.13 11.4 0.0 0.35 10.0 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain Phage_Nu1 PF07471.12 KXX82673.1 - 1.9 8.2 6.6 0.57 9.9 0.1 2.6 3 0 0 3 3 3 0 Phage DNA packaging protein Nu1 Ank_2 PF12796.7 KXX82674.1 - 1.6e-90 297.8 2.1 1.3e-12 48.2 0.1 5.8 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX82674.1 - 7.8e-51 169.8 1.3 5.9e-11 42.7 0.0 8.3 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KXX82674.1 - 4.7e-48 159.6 0.7 2.5e-05 24.5 0.0 10.5 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.6 KXX82674.1 - 6.2e-44 142.9 0.1 0.0044 17.4 0.0 10.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KXX82674.1 - 1.5e-40 136.7 1.0 1.4e-08 34.8 0.0 8.9 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Cation_ATPase_C PF00689.21 KXX82674.1 - 0.3 10.8 1.9 18 5.0 0.2 2.4 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Zn_clus PF00172.18 KXX82675.1 - 0.002 18.2 6.5 0.0024 18.0 4.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF382 PF04037.13 KXX82675.1 - 0.089 13.0 0.6 0.31 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF382) Beta-lactamase PF00144.24 KXX82677.1 - 5.4e-35 121.2 0.1 7.3e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase zf-3CxxC PF13695.6 KXX82678.1 - 2.4e-17 63.2 0.0 3.4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding domain Methyltransf_23 PF13489.6 KXX82679.1 - 1.9e-23 83.1 0.0 3.2e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82679.1 - 8.5e-14 52.0 0.0 2.6e-13 50.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82679.1 - 2.9e-12 47.1 0.0 6.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX82679.1 - 6.1e-09 36.5 0.0 3.5e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82679.1 - 1.6e-08 34.5 0.0 0.0008 19.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KXX82679.1 - 2.2e-07 30.5 0.0 2.9e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXX82679.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXX82679.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXX82679.1 - 0.0023 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KXX82679.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 KXX82679.1 - 0.047 13.4 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KXX82679.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KXX82679.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KXX82679.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain MMR_HSR1 PF01926.23 KXX82681.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.7 1 1 1 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXX82681.1 - 0.45 10.5 0.0 0.45 10.5 0.0 3.7 2 1 0 2 2 2 0 Dynamin family Peptidase_U57 PF05582.12 KXX82681.1 - 5.9 6.1 19.7 0.85 8.8 15.4 1.8 1 1 1 2 2 2 0 YabG peptidase U57 BASP1 PF05466.12 KXX82682.1 - 0.091 12.8 4.1 0.13 12.3 4.1 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF3440 PF11922.8 KXX82682.1 - 0.3 10.7 1.9 9.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) RR_TM4-6 PF06459.12 KXX82682.1 - 0.55 10.0 8.9 0.87 9.4 8.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cupin_8 PF13621.6 KXX82682.1 - 2.6 7.7 5.2 4 7.1 5.2 1.2 1 0 0 1 1 1 0 Cupin-like domain Abhydrolase_6 PF12697.7 KXX82683.1 - 2.6e-17 64.2 8.4 3.4e-17 63.8 8.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX82683.1 - 0.00088 19.0 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX82683.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MOSC PF03473.17 KXX82684.1 - 1.4e-29 102.7 0.0 2.2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXX82684.1 - 2.3e-13 50.1 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Fungal_trans PF04082.18 KXX82685.1 - 9.1e-19 67.5 0.0 1.9e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXX82685.1 - 4.8e-09 36.2 13.4 0.0002 21.7 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX82685.1 - 1.9e-06 28.0 12.8 2.3e-06 27.8 7.1 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX82685.1 - 0.00018 22.0 12.9 0.038 14.8 2.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger DUF1908 PF08926.11 KXX82685.1 - 0.019 14.1 0.0 0.019 14.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) zf-C2H2_jaz PF12171.8 KXX82685.1 - 1.3 9.4 3.2 0.8 10.1 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX82685.1 - 2.3 8.7 4.9 0.59 10.6 0.9 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FA_desaturase PF00487.24 KXX82686.1 - 3.1e-27 96.0 28.7 5.1e-27 95.3 28.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXX82686.1 - 3.2e-09 37.1 0.0 5.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) GTP_EFTU PF00009.27 KXX82687.1 - 4.6e-18 65.5 0.0 9.8e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXX82687.1 - 1.6e-09 38.1 0.5 7.3e-09 35.9 0.4 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXX82687.1 - 0.00026 21.3 0.0 0.00067 19.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXX82687.1 - 0.00038 20.5 0.4 0.0013 18.8 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX82687.1 - 0.002 18.1 1.1 0.81 9.6 0.4 2.5 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 KXX82687.1 - 0.015 15.5 0.2 0.17 12.1 0.1 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KXX82687.1 - 0.015 15.0 0.3 1.1 8.9 0.1 3.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KXX82687.1 - 0.085 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Dynamin family PIG-L PF02585.17 KXX82688.1 - 2.2e-26 93.0 0.0 3.7e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Polysacc_deac_1 PF01522.21 KXX82690.1 - 1.2e-28 99.5 0.1 2.5e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase ArAE_2_N PF10337.9 KXX82691.1 - 4.9e-41 141.3 5.6 2e-36 126.0 6.4 3.3 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KXX82691.1 - 1.1e-18 67.6 16.1 1.1e-18 67.6 16.1 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KXX82691.1 - 5.1e-07 29.8 0.0 0.0027 17.6 0.0 2.8 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 ALMT PF11744.8 KXX82691.1 - 0.047 12.5 7.7 0.096 11.5 7.7 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter OST3_OST6 PF04756.13 KXX82691.1 - 1.5 8.1 7.3 0.21 10.9 1.6 2.3 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Cutinase PF01083.22 KXX82693.1 - 4.1e-31 108.3 0.1 3.1e-27 95.7 0.0 2.0 2 0 0 2 2 2 2 Cutinase PE-PPE PF08237.11 KXX82693.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KXX82693.1 - 0.01 15.6 0.1 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 KXX82693.1 - 0.017 15.0 0.0 0.043 13.7 0.0 1.5 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KXX82693.1 - 0.06 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) E1-E2_ATPase PF00122.20 KXX82695.1 - 9.4e-35 119.8 20.0 7.2e-29 100.6 0.3 4.0 5 0 0 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 KXX82695.1 - 9.9e-18 65.2 0.0 1.1e-16 61.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXX82695.1 - 9.5e-17 60.9 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 KXX82695.1 - 4.7e-12 46.0 14.8 9.2e-08 32.0 7.8 3.6 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KXX82695.1 - 8.5e-12 44.6 0.4 4.9e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXX82695.1 - 0.0038 17.0 0.4 0.0063 16.3 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KXX82696.1 - 1.6e-28 99.5 0.0 2.2e-15 56.7 0.0 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82696.1 - 5.8e-21 75.1 0.0 1.7e-11 44.1 0.0 3.0 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82696.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1967 PF09269.11 KXX82696.1 - 0.072 13.0 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Pectate_lyase_3 PF12708.7 KXX82698.1 - 1e-98 329.5 6.0 1.8e-86 289.5 0.2 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXX82698.1 - 1.1e-07 31.4 2.3 0.013 15.2 0.2 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.13 KXX82698.1 - 0.027 13.8 0.1 0.059 12.6 0.1 1.5 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) HET PF06985.11 KXX82699.1 - 1e-28 100.5 0.0 2e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 KXX82699.1 - 0.0079 16.0 13.9 0.0079 16.0 13.9 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type Pept_S41_N PF18294.1 KXX82699.1 - 0.09 12.8 0.1 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain ApbA_C PF08546.11 KXX82700.1 - 2.6e-32 111.6 0.1 4.2e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXX82700.1 - 5.8e-25 87.7 0.0 1.9e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Glyco_hydro_7 PF00840.20 KXX82701.1 - 8.9e-150 499.2 0.1 1e-149 499.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FAD_binding_3 PF01494.19 KXX82702.1 - 1.1e-16 61.0 4.0 3.8e-10 39.5 0.4 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXX82702.1 - 1e-08 34.8 0.1 0.00025 20.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX82702.1 - 1.4e-08 34.3 0.0 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXX82702.1 - 2e-08 34.3 0.6 0.0013 18.4 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX82702.1 - 4.9e-07 28.8 0.3 0.00014 20.7 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KXX82702.1 - 8.1e-07 29.2 0.1 2.6e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXX82702.1 - 2.6e-05 23.8 0.4 6.1e-05 22.5 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXX82702.1 - 0.00015 21.2 0.0 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXX82702.1 - 0.00048 19.3 0.1 0.0031 16.7 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXX82702.1 - 0.00051 19.5 0.1 1 8.6 0.0 3.2 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXX82702.1 - 0.00075 18.7 0.1 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXX82702.1 - 0.0012 18.2 0.0 0.007 15.7 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXX82702.1 - 0.0045 16.3 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXX82702.1 - 0.03 14.9 0.0 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXX82702.1 - 0.17 11.7 0.1 0.39 10.6 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KXX82702.1 - 0.45 9.3 2.8 0.86 8.4 0.1 2.5 3 1 1 4 4 4 0 Tryptophan halogenase p450 PF00067.22 KXX82703.1 - 8e-49 166.6 0.0 1.5e-48 165.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KXX82703.1 - 3.2e-16 59.6 0.0 5.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX82703.1 - 1.8e-05 24.7 0.0 4.2e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Laminin_G_3 PF13385.6 KXX82704.1 - 0.0015 18.7 0.1 0.0022 18.2 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF747 PF05346.11 KXX82705.1 - 4e-123 410.9 2.9 5.1e-123 410.6 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF3886 PF13025.6 KXX82705.1 - 0.53 10.5 7.4 1.5 9.1 7.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Acetyltransf_1 PF00583.25 KXX82706.1 - 3.1e-06 27.4 0.0 4.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX82706.1 - 3.8e-05 24.0 0.0 5.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXX82706.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.22 KXX82707.1 - 1.2e-66 225.4 0.0 1.6e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Complex1_LYR_2 PF13233.6 KXX82707.1 - 0.12 13.1 0.3 1.6 9.5 0.2 2.5 2 1 0 2 2 2 0 Complex1_LYR-like Peptidase_C32 PF05411.12 KXX82707.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase Sugar_tr PF00083.24 KXX82708.1 - 1.5e-67 228.5 15.4 2.3e-67 227.8 15.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX82708.1 - 1.2e-14 54.0 25.2 4.9e-13 48.7 2.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXX82708.1 - 0.0069 14.7 0.3 0.0069 14.7 0.3 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KXX82708.1 - 0.57 9.4 13.6 0.056 12.7 2.5 2.4 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB DUF1129 PF06570.11 KXX82708.1 - 3.1 7.2 14.1 0.084 12.3 0.9 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1129) Aldedh PF00171.22 KXX82709.1 - 8.7e-156 519.0 1.0 9.8e-156 518.9 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXX82709.1 - 0.013 14.9 0.1 0.12 11.8 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Dimeth_Pyl PF09505.10 KXX82709.1 - 0.083 11.4 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) FAD_binding_3 PF01494.19 KXX82710.1 - 1e-12 48.0 2.3 3.3e-08 33.2 0.7 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXX82710.1 - 1.3e-09 37.8 0.2 5.9e-05 22.4 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX82710.1 - 1.4e-06 27.7 0.1 2.8e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX82710.1 - 5.2e-06 26.6 0.1 1.7e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXX82710.1 - 0.00011 22.6 0.1 0.006 17.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXX82710.1 - 0.00012 21.3 0.0 0.00027 20.2 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXX82710.1 - 0.00015 21.3 0.1 0.00027 20.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX82710.1 - 0.00026 19.8 0.0 0.0014 17.5 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KXX82710.1 - 0.001 18.0 0.1 0.9 8.3 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 KXX82710.1 - 0.0041 16.7 0.1 0.0095 15.6 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXX82710.1 - 0.027 13.8 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXX82710.1 - 0.074 12.3 0.1 0.17 11.1 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXX82710.1 - 0.11 11.7 0.0 5.4 6.2 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXX82710.1 - 0.16 11.0 0.0 8 5.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXX82710.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amidohydro_2 PF04909.14 KXX82711.1 - 2.1e-36 126.2 1.0 2.8e-36 125.8 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase NACHT PF05729.12 KXX82712.1 - 4.1e-12 46.3 0.0 4.1e-12 46.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX82712.1 - 0.00017 22.0 0.5 0.00099 19.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KXX82712.1 - 0.0016 19.0 0.3 0.01 16.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KXX82712.1 - 0.0097 16.3 0.0 0.038 14.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXX82712.1 - 0.05 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 KXX82712.1 - 0.2 12.1 3.3 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 KXX82712.1 - 1.6 8.2 11.3 3.3 7.2 11.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DLH PF01738.18 KXX82713.1 - 1.5e-27 96.6 0.0 1.7e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXX82713.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF915 PF06028.11 KXX82713.1 - 0.035 13.4 0.0 0.73 9.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Glyco_hydro_10 PF00331.20 KXX82714.1 - 2.9e-95 319.1 0.0 3.4e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Ferric_reduct PF01794.19 KXX82715.1 - 1.2e-19 70.6 15.5 1.2e-19 70.6 15.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXX82715.1 - 7.7e-07 29.2 0.0 1e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 KXX82715.1 - 9.4e-06 25.8 0.6 0.18 11.9 0.4 2.7 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Cyt-b5 PF00173.28 KXX82716.1 - 5.9e-14 52.0 0.0 1.4e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 KXX82716.1 - 1.1e-13 50.8 0.0 1.1e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 KXX82716.1 - 1.7e-10 40.9 0.0 5.4e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXX82716.1 - 5.3e-08 33.5 0.0 2e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain 2-Hacid_dh_C PF02826.19 KXX82717.1 - 1.4e-45 154.8 0.0 1.8e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXX82717.1 - 0.00049 19.8 0.0 0.00078 19.1 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 KXX82717.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ELFV_dehydrog PF00208.21 KXX82717.1 - 0.2 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SAICAR_synt PF01259.18 KXX82718.1 - 2e-95 319.2 0.0 2.6e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase HEAT_EZ PF13513.6 KXX82719.1 - 8.2e-16 58.1 14.3 3.3e-06 27.5 0.1 10.1 8 2 3 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.6 KXX82719.1 - 6.8e-14 52.0 19.6 0.026 14.9 1.9 8.8 6 1 4 10 10 10 6 HEAT repeats HEAT PF02985.22 KXX82719.1 - 5.2e-13 48.1 8.6 0.016 15.4 0.0 9.2 10 0 0 10 10 8 3 HEAT repeat IBN_N PF03810.19 KXX82719.1 - 3.4e-09 36.5 0.8 8.6e-08 32.0 0.3 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KXX82719.1 - 1.6e-08 35.0 0.3 0.76 10.4 0.0 5.6 4 3 1 5 5 5 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXX82719.1 - 7.6e-08 32.6 4.2 0.00024 21.2 0.0 4.3 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KXX82719.1 - 1.4e-05 24.9 0.0 14 5.3 0.0 5.0 3 2 2 5 5 5 0 rRNA processing/ribosome biogenesis ParcG PF10274.9 KXX82719.1 - 5.3e-05 23.4 0.9 0.52 10.4 0.1 4.6 4 1 0 5 5 5 1 Parkin co-regulated protein CLASP_N PF12348.8 KXX82719.1 - 0.00067 19.3 0.3 0.036 13.6 0.0 3.5 4 1 0 4 4 4 1 CLASP N terminal LcrG PF07216.12 KXX82719.1 - 0.0015 18.4 1.3 0.015 15.2 0.0 3.2 4 0 0 4 4 3 1 LcrG protein RTP1_C1 PF10363.9 KXX82719.1 - 0.0035 17.5 0.8 0.92 9.7 0.0 4.1 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 KXX82719.1 - 0.0065 15.6 3.3 0.18 10.9 0.3 3.7 1 1 2 3 3 3 1 Interferon-related developmental regulator (IFRD) TIP120 PF08623.10 KXX82719.1 - 0.021 14.6 0.3 0.87 9.3 0.0 3.5 3 1 0 3 3 3 0 TATA-binding protein interacting (TIP20) Arm PF00514.23 KXX82719.1 - 0.023 14.8 10.8 15 5.8 0.1 7.0 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat TFCD_C PF12612.8 KXX82719.1 - 0.042 13.7 0.1 0.72 9.7 0.1 3.2 1 1 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF577 PF04510.12 KXX82719.1 - 0.14 12.1 0.7 0.97 9.3 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF577) Importin_rep_4 PF18808.1 KXX82719.1 - 0.4 11.0 8.2 11 6.3 0.1 5.0 5 0 0 5 5 4 0 Importin repeat 2CSK_N PF08521.10 KXX82720.1 - 0.0055 16.8 0.1 0.014 15.5 0.0 1.5 1 1 1 2 2 2 1 Two-component sensor kinase N-terminal F-box-like PF12937.7 KXX82722.1 - 3.1e-08 33.4 1.8 8.4e-08 32.0 1.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX82722.1 - 5.8e-05 22.9 1.7 0.00012 21.8 1.7 1.6 1 0 0 1 1 1 1 F-box domain 7tm_2 PF00002.24 KXX82723.1 - 0.2 10.9 3.7 0.35 10.1 3.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Abhydrolase_3 PF07859.13 KXX82725.1 - 7.9e-40 137.0 0.0 9.9e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXX82725.1 - 4e-05 22.7 0.0 6.8e-05 21.9 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 KXX82725.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase tRNA-synt_2 PF00152.20 KXX82726.1 - 7.5e-73 245.3 0.0 1.1e-72 244.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KXX82726.1 - 7.5e-24 84.3 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KXX82726.1 - 9.5e-08 31.9 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXX82726.1 - 0.0072 15.8 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3328 PF11807.8 KXX82728.1 - 4.9e-45 154.0 1.8 6.2e-45 153.7 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GMC_oxred_N PF00732.19 KXX82729.1 - 5.1e-58 196.8 0.0 7.1e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX82729.1 - 4.4e-34 118.1 0.0 1.5e-33 116.4 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX82729.1 - 1.7e-08 34.0 0.9 8.6e-05 21.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXX82729.1 - 2.3e-06 27.5 3.4 4.3e-05 23.3 3.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXX82729.1 - 4.9e-05 22.7 0.1 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXX82729.1 - 0.00037 19.8 0.2 0.006 15.9 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX82729.1 - 0.00061 18.6 0.2 0.49 9.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KXX82729.1 - 0.0083 16.3 0.1 0.026 14.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX82729.1 - 0.0084 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXX82729.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KXX82729.1 - 0.04 14.2 0.1 0.097 12.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KXX82729.1 - 0.058 12.6 0.2 0.18 11.0 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain RTA1 PF04479.13 KXX82731.1 - 4.5e-66 222.4 11.0 4.5e-66 222.4 11.0 1.6 2 0 0 2 2 2 1 RTA1 like protein Ank PF00023.30 KXX82733.1 - 2.2e-30 103.8 2.1 1.2e-05 25.6 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.7 KXX82733.1 - 5.4e-27 94.2 0.0 1.6e-10 41.5 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXX82733.1 - 1.8e-21 73.9 0.1 0.0011 19.2 0.0 6.8 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KXX82733.1 - 3.9e-19 68.4 3.7 4.1e-08 33.3 0.1 5.5 5 2 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX82733.1 - 3.2e-17 62.6 0.0 0.00047 20.7 0.0 6.1 3 2 3 6 6 6 4 Ankyrin repeats (many copies) DUF1996 PF09362.10 KXX82734.1 - 3e-84 282.7 0.7 4.1e-84 282.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NUDIX PF00293.28 KXX82734.1 - 2.2e-11 43.9 0.2 2.2e-11 43.9 0.2 1.9 2 0 0 2 2 2 1 NUDIX domain GFO_IDH_MocA PF01408.22 KXX82735.1 - 2.4e-16 60.6 0.0 4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXX82735.1 - 0.085 13.5 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain SH3_9 PF14604.6 KXX82736.1 - 4.2e-10 39.3 0.2 8.8e-07 28.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KXX82736.1 - 3.3e-06 26.7 0.3 0.0026 17.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXX82736.1 - 0.00082 18.9 1.4 0.0075 15.9 0.1 2.5 2 0 0 2 2 2 1 SH3 domain KinB_sensor PF16767.5 KXX82737.1 - 0.069 13.6 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF1996 PF09362.10 KXX82738.1 - 8.4e-46 156.9 0.1 1e-45 156.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Vac17 PF17321.2 KXX82739.1 - 0.25 10.7 0.0 0.31 10.4 0.0 1.0 1 0 0 1 1 1 0 Vacuole-related protein 17 DUF1996 PF09362.10 KXX82740.1 - 2.6e-82 276.3 2.5 3.5e-82 275.9 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MFS_1 PF07690.16 KXX82741.1 - 8.7e-07 28.2 39.3 2.6e-05 23.3 39.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Asp PF00026.23 KXX82742.1 - 3.4e-32 112.1 0.0 4.3e-17 62.5 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KXX82742.1 - 0.0002 21.9 0.1 15 6.3 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease TAXi_N PF14543.6 KXX82742.1 - 0.0018 18.5 0.4 5.9 7.1 0.0 3.2 3 1 0 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KXX82742.1 - 0.042 13.6 0.0 0.17 11.7 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KXX82742.1 - 0.08 13.5 0.0 71 4.1 0.0 3.6 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease SGL PF08450.12 KXX82743.1 - 6.3e-05 22.7 0.1 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXX82743.1 - 0.036 14.1 0.1 27 5.1 0.0 4.9 4 1 1 5 5 5 0 NHL repeat Apyrase PF06079.11 KXX82743.1 - 0.17 11.0 0.4 0.89 8.7 0.2 1.9 2 0 0 2 2 2 0 Apyrase RCC1_2 PF13540.6 KXX82743.1 - 0.53 10.2 15.3 1.6 8.6 1.1 4.6 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat Acetyltransf_2 PF00797.17 KXX82744.1 - 2.4e-44 151.9 0.0 3e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase DUF4448 PF14610.6 KXX82745.1 - 2e-34 119.0 0.0 2.9e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 KXX82745.1 - 0.0013 18.1 4.7 0.0034 16.8 4.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 KXX82745.1 - 0.035 14.2 0.1 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment K_oxygenase PF13434.6 KXX82746.1 - 1.4e-108 363.1 0.0 1.7e-108 362.8 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXX82746.1 - 1.5e-08 34.3 0.0 6.3e-08 32.2 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX82746.1 - 3.4e-05 23.9 0.0 0.00034 20.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXX82746.1 - 6.1e-05 22.4 0.0 0.00053 19.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GBP_PSP PF02425.15 KXX82746.1 - 0.0097 15.5 0.3 0.022 14.4 0.3 1.5 1 0 0 1 1 1 1 Paralytic/GBP/PSP peptide Condensation PF00668.20 KXX82747.1 - 4.1e-130 434.5 0.0 3e-28 98.7 0.0 6.0 5 1 0 5 5 5 5 Condensation domain AMP-binding PF00501.28 KXX82747.1 - 1e-83 281.4 0.0 1.5e-83 280.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXX82747.1 - 1.1e-33 115.4 3.3 3.5e-10 40.1 0.0 5.0 5 0 0 5 5 5 4 Phosphopantetheine attachment site Transferase PF02458.15 KXX82747.1 - 0.0039 15.9 0.0 0.88 8.1 0.0 2.3 2 0 0 2 2 2 2 Transferase family WW PF00397.26 KXX82748.1 - 1.6e-09 37.7 4.5 1.6e-09 37.7 4.5 2.7 3 0 0 3 3 3 1 WW domain FF PF01846.19 KXX82748.1 - 1.4e-08 34.8 0.4 1.4e-08 34.8 0.4 2.8 3 0 0 3 3 3 1 FF domain DUF5641 PF18701.1 KXX82748.1 - 0.33 11.2 4.8 0.2 11.8 1.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Alpha_GJ PF03229.13 KXX82749.1 - 0.32 11.6 5.7 0.6 10.7 5.7 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF1264 PF06884.11 KXX82750.1 - 2.8e-73 245.1 0.0 3.3e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) SET PF00856.28 KXX82751.1 - 0.0032 17.9 0.0 0.014 15.8 0.0 2.0 2 0 0 2 2 2 1 SET domain Ras PF00071.22 KXX82752.1 - 1.7e-65 219.5 0.5 2.1e-65 219.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX82752.1 - 6.9e-36 123.1 0.1 1.3e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX82752.1 - 3.3e-16 59.2 0.1 3.9e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXX82752.1 - 1e-05 25.5 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXX82752.1 - 2.4e-05 24.4 0.0 9.6e-05 22.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXX82752.1 - 8.1e-05 22.2 0.5 0.00018 21.1 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXX82752.1 - 0.00026 20.4 0.1 0.00034 20.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXX82752.1 - 0.00041 19.8 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KXX82752.1 - 0.0024 18.3 0.1 0.17 12.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KXX82752.1 - 0.0041 16.7 0.0 0.026 14.1 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KXX82752.1 - 0.0096 16.3 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain LANC_like PF05147.13 KXX82752.1 - 0.029 13.0 0.1 0.13 10.8 0.0 2.0 1 1 1 2 2 2 0 Lanthionine synthetase C-like protein Septin PF00735.18 KXX82752.1 - 0.033 13.5 0.1 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 KXX82752.1 - 0.037 14.3 0.0 0.069 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXX82752.1 - 0.052 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KXX82752.1 - 0.07 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 KXX82752.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXX82752.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXX82752.1 - 0.098 13.2 0.1 0.18 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KXX82752.1 - 0.11 12.3 0.0 1.3 8.8 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Endonuclease_5 PF04493.14 KXX82752.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease V MMU163 PF17119.5 KXX82753.1 - 1.1e-81 273.6 0.0 2e-81 272.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 KXX82753.1 - 0.16 12.0 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Kinesin PF00225.23 KXX82754.1 - 1.4e-93 313.4 0.0 1.4e-93 313.4 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KXX82754.1 - 9.8e-18 64.5 0.0 2.8e-14 53.3 0.0 3.0 1 1 1 2 2 2 2 Microtubule binding Chordopox_A30L PF06015.12 KXX82754.1 - 0.037 13.9 0.1 0.18 11.7 0.1 2.2 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Img2 PF05046.14 KXX82754.1 - 0.12 12.7 0.2 2.6 8.4 0.0 3.4 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) AMP-binding PF00501.28 KXX82755.1 - 7.1e-88 295.0 0.1 8.7e-88 294.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX82755.1 - 1.6e-26 93.1 0.8 5.2e-25 88.2 0.4 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXX82755.1 - 2.4e-18 65.8 0.4 6.2e-18 64.5 0.4 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 KXX82755.1 - 0.14 12.1 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) ADH_N PF08240.12 KXX82756.1 - 4.1e-28 97.4 0.2 7.3e-28 96.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX82756.1 - 9.2e-24 83.9 0.0 1.8e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXX82756.1 - 4.5e-05 24.5 0.0 7.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXX82756.1 - 0.0031 16.8 0.1 0.0048 16.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KXX82756.1 - 0.013 15.0 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KXX82756.1 - 0.077 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2226 PF09987.9 KXX82756.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Actin PF00022.19 KXX82757.1 - 2.7e-85 286.4 0.0 8e-83 278.3 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXX82757.1 - 0.15 10.8 0.1 3.7 6.3 0.1 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 KXX82758.1 - 1e-37 129.9 2.9 6.9e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 Asparaginase Reprolysin_5 PF13688.6 KXX82760.1 - 1.7e-60 204.6 4.4 5.7e-60 202.8 4.4 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KXX82760.1 - 4.3e-51 173.6 1.0 9e-51 172.5 1.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXX82760.1 - 2.8e-47 161.0 3.7 4.7e-47 160.3 0.8 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KXX82760.1 - 4.4e-17 62.6 31.0 4.4e-17 62.6 31.0 4.5 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KXX82760.1 - 5.7e-11 43.0 0.0 1.6e-10 41.6 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KXX82760.1 - 3.5e-05 23.8 9.6 3.5e-05 23.8 9.6 3.0 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KXX82760.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide TPR_1 PF00515.28 KXX82761.1 - 3.7e-54 178.4 28.7 5.7e-08 32.3 0.1 10.3 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KXX82761.1 - 6.4e-51 166.4 21.4 4.6e-06 26.3 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KXX82761.1 - 4.1e-35 117.1 19.0 6.6e-06 25.9 0.0 10.5 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 KXX82761.1 - 3e-28 98.2 14.2 2.1e-06 28.3 0.1 7.0 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.6 KXX82761.1 - 1.9e-26 90.5 18.4 0.00012 22.6 0.0 9.3 2 2 8 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 KXX82761.1 - 1.1e-25 88.1 18.4 0.0014 18.9 0.1 10.1 10 1 1 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXX82761.1 - 2.8e-24 85.4 20.2 0.00026 21.4 0.4 7.0 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXX82761.1 - 5.5e-24 84.3 19.9 1.3e-05 25.4 0.7 7.5 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 KXX82761.1 - 3.5e-23 80.7 15.0 0.014 16.0 0.9 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXX82761.1 - 1.2e-19 69.6 31.8 1.1e-05 25.1 0.1 9.6 5 2 4 9 9 9 5 TPR repeat TPR_7 PF13176.6 KXX82761.1 - 2.9e-19 67.6 13.3 0.016 15.2 0.1 9.5 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 KXX82761.1 - 6.4e-16 58.3 17.6 0.0028 17.8 0.3 7.1 1 1 6 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KXX82761.1 - 6.1e-14 52.0 6.8 1.8e-07 31.3 1.6 3.9 2 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KXX82761.1 - 1.2e-11 44.3 9.6 0.0016 17.8 2.6 4.6 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 KXX82761.1 - 3.5e-06 26.9 6.4 0.19 11.4 0.0 5.1 3 2 1 5 5 5 2 Tetratricopeptide repeat-like domain BTAD PF03704.17 KXX82761.1 - 0.00016 22.1 9.5 1.7 9.0 0.7 3.7 3 1 1 4 4 4 3 Bacterial transcriptional activator domain TPR_20 PF14561.6 KXX82761.1 - 0.0005 20.4 3.9 0.91 9.9 0.0 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 KXX82761.1 - 0.35 10.9 14.2 7.8 6.6 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX82761.1 - 0.57 10.1 21.0 30 4.7 0.2 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Ribosomal_L3 PF00297.22 KXX82762.1 - 3.8e-181 602.0 12.6 4.3e-181 601.8 12.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Smg4_UPF3 PF03467.15 KXX82763.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family UNC45-central PF11701.8 KXX82764.1 - 1.4e-56 190.7 0.1 1.4e-55 187.5 0.0 2.7 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central IFRD PF05004.13 KXX82764.1 - 0.071 12.2 3.6 1.6 7.8 0.2 3.3 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KXX82764.1 - 1.3 9.5 18.5 13 6.3 6.0 5.5 3 1 2 5 5 5 0 HEAT repeats ERCC4 PF02732.15 KXX82765.1 - 4.9e-26 91.8 0.0 1e-25 90.7 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain DUF4355 PF14265.6 KXX82765.1 - 0.46 10.7 9.4 0.83 9.9 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) SAGA-Tad1 PF12767.7 KXX82765.1 - 0.62 9.8 4.7 2 8.1 1.6 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit NARP1 PF12569.8 KXX82765.1 - 2 7.2 6.8 3.1 6.6 6.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3391 PF11871.8 KXX82765.1 - 2.2 8.8 11.8 11 6.6 7.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Tfb4 PF03850.14 KXX82766.1 - 7.1e-84 281.6 7.3 3.1e-61 207.3 0.0 2.0 2 0 0 2 2 2 2 Transcription factor Tfb4 tRNA_int_end_N2 PF12928.7 KXX82768.1 - 2.4e-16 59.6 0.3 5.3e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KXX82768.1 - 0.086 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain WW PF00397.26 KXX82769.1 - 5.1e-10 39.3 0.2 1.4e-09 37.8 0.2 1.9 1 0 0 1 1 1 1 WW domain GDPD PF03009.17 KXX82770.1 - 5.4e-72 242.6 0.0 1.2e-71 241.5 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KXX82770.1 - 1e-37 128.6 4.7 4.8e-17 62.3 0.1 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX82770.1 - 3.8e-28 97.5 3.2 4.7e-09 36.6 0.2 5.7 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXX82770.1 - 1.2e-19 70.1 0.9 1.7e-07 31.4 0.0 5.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX82770.1 - 8.1e-18 64.0 2.7 0.00037 20.8 0.1 6.1 5 0 0 5 5 5 3 Ankyrin repeat SPX PF03105.19 KXX82770.1 - 4.4e-17 63.1 21.0 4.2e-08 33.5 0.0 4.9 4 2 1 5 5 5 3 SPX domain Ank_3 PF13606.6 KXX82770.1 - 5.9e-16 57.0 1.1 0.0027 18.0 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat ABC_membrane_2 PF06472.15 KXX82771.1 - 6.3e-104 347.1 1.0 1e-103 346.4 1.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXX82771.1 - 1.6e-16 61.1 0.0 4.1e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXX82771.1 - 0.0003 20.7 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXX82771.1 - 0.012 16.2 0.1 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX82771.1 - 0.027 14.9 0.4 0.34 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 KXX82771.1 - 0.078 12.4 0.1 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KXX82771.1 - 0.083 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KXX82771.1 - 0.091 12.2 0.1 0.26 10.7 0.1 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KXX82771.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Pga1 PF10333.9 KXX82772.1 - 6.6e-05 22.8 0.1 0.00015 21.7 0.1 1.6 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Rpr2 PF04032.16 KXX82773.1 - 8.2e-13 48.5 0.8 1.7e-12 47.5 0.2 1.8 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ZPR1 PF03367.13 KXX82774.1 - 4.6e-113 374.3 0.2 1.4e-57 194.0 0.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain SAM_decarbox PF01536.16 KXX82774.1 - 0.12 11.4 0.1 2 7.3 0.0 2.6 3 1 1 4 4 4 0 Adenosylmethionine decarboxylase DUF866 PF05907.13 KXX82776.1 - 8.3e-66 220.7 0.1 9.2e-66 220.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) HalOD2 PF18547.1 KXX82776.1 - 0.037 13.9 1.4 0.21 11.5 0.2 2.3 2 0 0 2 2 2 0 Halobacterial output domain 2 RNHCP PF12647.7 KXX82776.1 - 0.21 11.5 2.0 6.4 6.8 0.2 2.2 1 1 1 2 2 2 0 RNHCP domain Zn_ribbon_SprT PF17283.2 KXX82776.1 - 0.31 11.0 6.2 2.4 8.2 6.2 2.1 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DUF4379 PF14311.6 KXX82776.1 - 0.33 11.3 3.5 0.33 11.3 1.9 1.9 1 1 0 1 1 1 0 Probable Zinc-ribbon domain RabGAP-TBC PF00566.18 KXX82777.1 - 8.7e-43 146.5 0.0 1.2e-41 142.7 0.0 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain kleA_kleC PF17383.2 KXX82778.1 - 0.0016 18.7 0.4 0.0034 17.7 0.4 1.5 1 0 0 1 1 1 1 Uncharacterized KorC regulated protein A Ank_4 PF13637.6 KXX82779.1 - 8.7e-29 99.5 0.5 1.1e-10 41.8 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX82779.1 - 6.5e-28 97.1 0.3 8.9e-19 67.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX82779.1 - 3.3e-26 91.0 5.0 1.1e-09 38.4 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXX82779.1 - 4.1e-24 83.9 4.7 1.5e-06 28.4 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KXX82779.1 - 1.6e-22 77.2 0.2 0.00011 22.3 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Imm_superinfect PF14373.6 KXX82779.1 - 2.5e-05 24.1 0.5 3.1 7.8 0.0 3.2 3 0 0 3 3 3 3 Superinfection immunity protein YlzJ PF14035.6 KXX82779.1 - 0.00037 20.7 0.0 1.2 9.4 0.0 3.1 3 0 0 3 3 3 1 YlzJ-like protein PEGA PF08308.11 KXX82779.1 - 0.02 14.8 0.0 4.2 7.3 0.0 3.4 3 1 0 3 3 3 0 PEGA domain VWA_3_C PF18571.1 KXX82779.1 - 0.69 9.8 5.3 27 4.7 0.2 3.5 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain ATP-grasp_2 PF08442.10 KXX82780.1 - 1.7e-76 256.3 0.6 1.7e-76 256.3 0.6 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KXX82780.1 - 9.6e-27 93.7 0.5 2e-26 92.7 0.5 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KXX82780.1 - 1.5e-07 31.1 0.3 5.4e-07 29.3 0.3 1.9 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXX82780.1 - 0.00065 19.5 1.5 0.017 14.9 0.2 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Lar_restr_allev PF14354.6 KXX82782.1 - 0.1 13.0 4.7 6.1 7.3 1.9 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF629 PF04780.12 KXX82782.1 - 0.19 10.2 1.2 0.31 9.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) DUF3883 PF13020.6 KXX82783.1 - 2.5e-05 24.2 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) MAPEG PF01124.18 KXX82785.1 - 6.5e-18 64.9 1.2 8.4e-18 64.5 1.2 1.1 1 0 0 1 1 1 1 MAPEG family DUF943 PF06092.12 KXX82785.1 - 0.17 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) Myotub-related PF06602.14 KXX82786.1 - 0.0024 16.9 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Pro_isomerase PF00160.21 KXX82787.1 - 4.4e-47 160.3 0.0 5e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 KXX82788.1 - 1.3e-12 48.3 0.1 3.2e-11 43.8 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Aldose_epim PF01263.20 KXX82789.1 - 4.1e-48 164.2 0.1 5.9e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Ctf8 PF09696.10 KXX82789.1 - 4.7e-32 111.3 0.0 7e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Ctf8 ATP-synt_ab PF00006.25 KXX82790.1 - 1e-66 224.6 0.0 1.5e-66 224.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXX82790.1 - 2e-13 50.7 0.8 4e-13 49.7 0.8 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PGA2 PF07543.12 KXX82791.1 - 3.5 7.6 11.5 8 6.4 2.8 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 WD40 PF00400.32 KXX82792.1 - 1.4e-11 44.8 20.0 0.0039 18.0 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Sigma70_r1_2 PF00140.20 KXX82792.1 - 0.016 15.2 0.5 0.031 14.3 0.5 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DUF3494 PF11999.8 KXX82792.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) COPI_C PF06957.11 KXX82793.1 - 1.4 7.5 6.3 2.4 6.8 6.3 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus SDA1 PF05285.12 KXX82793.1 - 2.5 7.4 8.7 3.6 6.9 8.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXX82793.1 - 7.1 4.7 11.0 11 4.0 11.0 1.2 1 0 0 1 1 1 0 Nop14-like family G_glu_transpept PF01019.21 KXX82794.1 - 4.9e-160 533.7 0.0 6.1e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ribosomal_S8e PF01201.22 KXX82795.1 - 1.4e-47 161.3 0.1 1.7e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ago_PAZ PF18309.1 KXX82795.1 - 0.071 13.8 0.3 0.2 12.4 0.1 1.8 1 1 1 2 2 2 0 Argonaute PAZ domain DUF913 PF06025.12 KXX82796.1 - 1.1e-124 416.2 0.0 1.1e-124 416.2 0.0 6.1 5 1 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KXX82796.1 - 6.4e-122 407.4 0.0 6.4e-122 407.4 0.0 4.9 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KXX82796.1 - 1.8e-95 320.0 0.0 3.3e-95 319.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KXX82796.1 - 1.8e-26 90.7 16.8 8.9e-09 34.5 1.4 3.9 3 0 0 3 3 3 3 Ubiquitin binding region Pro_isomerase PF00160.21 KXX82797.1 - 1.2e-42 145.9 0.0 2.2e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PRP38_assoc PF12871.7 KXX82797.1 - 0.0066 17.0 31.6 0.0066 17.0 31.6 3.5 3 1 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TMEM247 PF15444.6 KXX82797.1 - 0.38 10.8 4.1 11 5.9 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 247 HSF_DNA-bind PF00447.17 KXX82798.1 - 4.6e-28 97.7 0.3 1e-27 96.5 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KXX82798.1 - 0.076 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Ets-domain Ribosomal_S6e PF01092.19 KXX82799.1 - 4.2e-57 191.5 0.0 8.4e-57 190.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Gas_vesicle_C PF01304.17 KXX82799.1 - 0.3 11.1 2.1 0.8 9.8 2.1 1.7 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Atg14 PF10186.9 KXX82799.1 - 6.5 5.7 8.9 8.6 5.3 8.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Diphthamide_syn PF01866.17 KXX82800.1 - 7.1e-116 386.9 0.0 9.1e-116 386.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Mcl1_mid PF12341.8 KXX82801.1 - 9.6e-98 327.2 0.0 6.2e-97 324.5 0.0 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KXX82801.1 - 1.1e-21 76.7 0.3 6.8e-08 33.1 0.1 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX82801.1 - 7e-16 58.3 0.0 1.2e-05 25.5 0.1 7.0 2 1 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXX82801.1 - 2.1e-05 23.7 0.0 0.0003 20.0 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 KXX82801.1 - 0.0058 16.5 0.0 0.06 13.2 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KXX82801.1 - 0.021 12.9 0.1 0.057 11.4 0.1 1.5 1 1 0 1 1 1 0 IKI3 family Ge1_WD40 PF16529.5 KXX82801.1 - 0.037 13.0 0.0 1.1 8.2 0.0 2.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 KXX82801.1 - 0.072 11.7 0.0 0.74 8.4 0.0 2.4 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.12 KXX82801.1 - 0.099 12.6 0.4 38 4.4 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DNA_pol_alpha_N PF12254.8 KXX82801.1 - 1.5 8.9 5.8 3.8 7.7 5.8 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal HSF_DNA-bind PF00447.17 KXX82802.1 - 2.6e-30 104.9 1.3 4.4e-30 104.1 1.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding GAT PF03127.14 KXX82802.1 - 0.17 12.2 0.1 11 6.4 0.1 2.3 2 0 0 2 2 2 0 GAT domain Ets PF00178.22 KXX82802.1 - 0.18 12.3 0.1 0.35 11.4 0.1 1.4 1 0 0 1 1 1 0 Ets-domain p450 PF00067.22 KXX82803.1 - 1.4e-50 172.4 0.0 1.5e-44 152.5 0.0 2.4 1 1 0 2 2 2 2 Cytochrome P450 F-box-like PF12937.7 KXX82804.1 - 0.0043 16.9 0.3 0.0085 16.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX82804.1 - 2.9 7.9 6.4 11 6.0 0.0 2.9 3 0 0 3 3 3 0 F-box domain Trp_halogenase PF04820.14 KXX82805.1 - 2.1e-27 96.1 0.3 2.8e-12 46.2 0.3 3.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KXX82805.1 - 1.7e-11 43.9 0.0 5.2e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX82805.1 - 7.4e-06 26.1 0.2 0.0001 22.5 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXX82805.1 - 1.6e-05 24.3 0.0 3.1e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXX82805.1 - 4.4e-05 23.0 0.0 7.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXX82805.1 - 0.0007 18.8 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXX82805.1 - 0.00092 18.4 0.1 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KXX82805.1 - 0.0017 18.0 2.6 0.074 12.6 0.5 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX82805.1 - 0.0035 16.1 0.1 0.0053 15.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXX82805.1 - 0.024 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UbiA PF01040.18 KXX82806.1 - 6e-28 97.8 29.5 1.1e-27 96.9 29.0 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family Fig1 PF12351.8 KXX82806.1 - 0.01 15.8 4.2 0.57 10.1 0.1 3.2 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 polyprenyl_synt PF00348.17 KXX82806.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Polyprenyl synthetase DUF3357 PF11837.8 KXX82806.1 - 6 7.4 8.4 19 5.8 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) CrgA PF06781.12 KXX82806.1 - 8 6.6 10.1 23 5.2 0.0 3.6 4 0 0 4 4 4 0 Cell division protein CrgA AMP-binding PF00501.28 KXX82807.1 - 8.4e-38 130.1 0.0 1.4e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXX82807.1 - 2.8e-18 66.0 0.0 4.4e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KXX82807.1 - 6.7e-08 32.3 0.0 2.1e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXX82807.1 - 1e-05 25.8 0.1 0.0001 22.6 0.1 2.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site eIF-5_eIF-2B PF01873.17 KXX82809.1 - 9.5e-41 138.4 0.2 1.6e-40 137.6 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.6 KXX82809.1 - 0.12 12.4 0.5 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon Arc_trans_TRASH PF08394.10 KXX82809.1 - 2.1 8.7 7.2 1.7 9.0 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain NmrA PF05368.13 KXX82810.1 - 1e-08 35.0 0.0 5.8e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXX82810.1 - 4.6e-07 29.9 0.0 4.8e-06 26.6 0.0 2.4 3 0 0 3 3 3 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXX82810.1 - 6.9e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXX82810.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KXX82810.1 - 0.079 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KXX82810.1 - 0.17 12.5 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent A_deaminase PF00962.22 KXX82811.1 - 4.6e-11 42.6 0.0 7.2e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DAO PF01266.24 KXX82812.1 - 7.2e-40 137.6 1.9 1.8e-39 136.3 1.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXX82812.1 - 4e-05 23.7 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXX82812.1 - 5.5e-05 22.4 0.1 0.047 12.8 0.3 3.0 2 1 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.19 KXX82812.1 - 0.00092 18.5 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXX82812.1 - 0.0036 16.6 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXX82812.1 - 0.0039 16.0 0.0 1.7 7.3 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KXX82812.1 - 0.0039 16.5 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXX82812.1 - 0.017 15.1 0.0 7.3 6.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXX82812.1 - 0.094 12.0 0.0 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2477 PF10631.9 KXX82814.1 - 0.01 16.5 2.0 0.019 15.6 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Abhydro_lipase PF04083.16 KXX82815.1 - 1.2e-20 72.9 0.0 2.4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KXX82815.1 - 1.6e-05 24.7 0.1 3.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX82815.1 - 0.0039 16.5 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Glyco_hydro_125 PF06824.11 KXX82816.1 - 6.4e-182 605.0 0.0 7.6e-182 604.8 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) SH3BGR PF04908.15 KXX82817.1 - 3.7e-05 23.8 0.0 9.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DUF1631 PF07793.11 KXX82817.1 - 6.3 5.1 9.1 8 4.7 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) AAA PF00004.29 KXX82818.1 - 1.2e-49 168.1 0.0 3.9e-43 147.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXX82818.1 - 9.5e-05 22.8 1.5 0.021 15.2 0.0 3.8 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXX82818.1 - 0.00014 21.7 0.0 0.00057 19.7 0.0 2.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KXX82818.1 - 0.00079 18.6 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_lid_3 PF17862.1 KXX82818.1 - 0.003 17.3 4.7 0.15 11.9 0.1 3.1 3 0 0 3 3 2 1 AAA+ lid domain AAA_2 PF07724.14 KXX82818.1 - 0.0035 17.5 0.0 0.0089 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KXX82818.1 - 0.0061 16.2 0.0 0.025 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXX82818.1 - 0.0064 16.9 0.0 0.037 14.4 0.0 2.4 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KXX82818.1 - 0.007 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXX82818.1 - 0.01 16.1 0.5 0.037 14.3 0.0 2.2 2 1 1 3 3 2 0 AAA domain TIP49 PF06068.13 KXX82818.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KXX82818.1 - 0.02 14.3 0.1 0.057 12.8 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXX82818.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KXX82818.1 - 0.029 13.7 0.0 0.085 12.2 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 KXX82818.1 - 0.032 14.8 0.1 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXX82818.1 - 0.037 13.6 0.1 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KXX82818.1 - 0.042 13.3 0.1 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KXX82818.1 - 0.07 13.4 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXX82818.1 - 0.088 12.5 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 KXX82818.1 - 0.092 12.8 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KXX82818.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF4710 PF15828.5 KXX82818.1 - 0.13 12.4 0.7 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) ABC_tran PF00005.27 KXX82818.1 - 0.18 12.3 0.2 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 KXX82818.1 - 0.27 10.4 0.7 4 6.5 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 KXX82818.1 - 0.41 10.8 0.0 0.41 10.8 0.0 2.2 3 0 0 3 3 1 0 AAA domain PNGaseA PF12222.8 KXX82819.1 - 5.1e-171 569.3 0.5 6.7e-171 568.9 0.5 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A AMP-binding PF00501.28 KXX82820.1 - 3.2e-261 866.1 0.0 1e-88 297.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KXX82820.1 - 5.9e-234 776.8 0.0 1.1e-90 304.5 1.2 4.1 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KXX82820.1 - 7.2e-44 148.0 0.0 9.3e-14 51.5 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXX82820.1 - 7.5e-29 100.5 0.0 2.4e-10 41.3 0.0 4.4 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 KXX82820.1 - 2.7e-25 89.8 0.0 6.6e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXX82820.1 - 0.00021 22.0 0.4 0.00095 19.8 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX82820.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXX82820.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.18 KXX82821.1 - 4.3e-07 29.9 9.7 8.5e-07 29.0 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 KXX82822.1 - 4e-65 220.3 0.0 1.7e-64 218.3 0.0 1.8 1 1 0 1 1 1 1 CoA-transferase family III 2OG-FeII_Oxy PF03171.20 KXX82823.1 - 3.6e-15 56.3 0.0 1.3e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXX82823.1 - 3.3e-12 47.2 0.0 5.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Lactamase_B_2 PF12706.7 KXX82824.1 - 2.9e-13 49.8 0.3 1.1e-11 44.6 0.3 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXX82824.1 - 2.9e-08 33.8 1.5 4.2e-07 30.0 1.5 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXX82824.1 - 0.023 14.7 3.3 0.14 12.1 0.9 2.5 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily K_channel_TID PF07941.11 KXX82824.1 - 1.3 9.6 4.5 2.4 8.7 4.5 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain AMP-binding PF00501.28 KXX82825.1 - 6.1e-45 153.6 0.0 1e-21 77.1 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KXX82825.1 - 6e-07 30.3 0.0 1.4e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ldh_1_C PF02866.18 KXX82826.1 - 5.4e-47 159.8 0.0 1.1e-46 158.9 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXX82826.1 - 1.1e-44 151.9 0.0 2.5e-44 150.8 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXX82826.1 - 1.9e-05 23.8 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KXX82826.1 - 0.19 11.3 0.1 0.74 9.3 0.1 1.9 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 KXX82826.1 - 0.19 12.2 0.5 0.62 10.5 0.1 2.1 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_61 PF03443.14 KXX82827.1 - 1.4e-53 181.9 0.0 1.8e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.7 KXX82828.1 - 9.8e-21 74.1 0.0 3.2e-13 50.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXX82828.1 - 4.4e-15 55.3 0.5 0.02 15.4 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KXX82828.1 - 6.8e-15 54.9 0.1 1.1e-05 25.6 0.1 3.6 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX82828.1 - 1.6e-14 52.6 0.0 0.00083 19.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KXX82828.1 - 2.1e-14 53.7 0.2 0.00022 21.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) adh_short PF00106.25 KXX82829.1 - 7.3e-35 120.2 0.2 9.5e-35 119.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82829.1 - 1.5e-29 103.2 0.1 1.8e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82829.1 - 3.6e-06 27.0 0.2 5.3e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXX82829.1 - 7.3e-05 22.3 0.0 0.031 13.6 0.0 2.6 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KXX82829.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding MARVEL PF01284.23 KXX82831.1 - 3.1e-22 79.2 16.1 3.7e-22 78.9 16.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain TMEM132D_C PF15706.5 KXX82831.1 - 0.074 12.8 1.2 0.14 12.0 0.1 1.9 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RP853 PF17542.2 KXX82831.1 - 1.2 8.1 3.6 1.4 7.9 3.6 1.2 1 0 0 1 1 1 0 Uncharacterized RP853 CsbD PF05532.12 KXX82832.1 - 9.4e-19 67.1 19.8 3.2e-12 46.2 1.6 3.1 2 1 1 3 3 3 3 CsbD-like BAR PF03114.18 KXX82833.1 - 8.6e-69 231.8 10.0 1.1e-68 231.5 10.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KXX82833.1 - 5.6e-15 54.7 0.2 1.2e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXX82833.1 - 4.3e-11 42.5 0.0 7.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX82833.1 - 1.5e-08 34.2 0.1 1.1e-07 31.4 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain TMPIT PF07851.13 KXX82833.1 - 0.12 11.6 8.5 0.41 9.8 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.19 KXX82834.1 - 5.8e-95 318.4 0.0 7e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXX82834.1 - 2.7e-06 26.9 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXX82834.1 - 6.7e-06 25.7 0.1 2.1e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KXX82834.1 - 0.0017 17.2 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KXX82834.1 - 0.056 12.0 0.0 0.085 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BOP1NT PF08145.12 KXX82835.1 - 3.6e-104 348.3 7.8 4.9e-104 347.9 7.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KXX82835.1 - 1.9e-19 69.6 0.8 3.4e-07 30.8 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX82835.1 - 1.6e-05 25.1 0.0 0.0021 18.3 0.0 3.5 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KXX82835.1 - 0.077 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KXX82835.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Lipase_GDSL_2 PF13472.6 KXX82836.1 - 9.2e-23 81.6 4.5 1.5e-22 80.8 4.5 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXX82836.1 - 6e-10 39.4 0.0 9.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amino_oxidase PF01593.24 KXX82837.1 - 8.2e-19 68.2 0.0 3.4e-18 66.2 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX82837.1 - 5.8e-11 42.5 0.0 1.9e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX82837.1 - 5.9e-07 29.4 0.0 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX82837.1 - 0.00057 19.2 0.0 0.0087 15.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX82837.1 - 0.0031 18.0 0.0 0.17 12.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX82837.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 KXX82837.1 - 0.088 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 MCRA family Mqo PF06039.15 KXX82837.1 - 0.19 10.2 0.0 6 5.3 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) zf-CCCH_2 PF14608.6 KXX82838.1 - 1.3e-13 50.8 61.3 4.9e-05 23.6 13.8 5.5 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Glyco_hydro_20 PF00728.22 KXX82839.1 - 1.6e-85 287.6 0.0 1.9e-85 287.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KXX82839.1 - 3.6e-34 118.3 0.0 6.7e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KXX82839.1 - 1e-06 29.6 0.1 1e-05 26.3 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 KXX82840.1 - 9e-54 182.9 0.0 1.3e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.21 KXX82841.1 - 2.2e-18 66.6 0.0 2.8e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXX82841.1 - 1.1e-07 31.0 0.0 1.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF4199 PF13858.6 KXX82842.1 - 0.48 10.8 3.5 0.88 9.9 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Glyco_hydro_16 PF00722.21 KXX82843.1 - 1.8e-42 144.8 0.3 2.8e-42 144.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I_N PF02919.15 KXX82844.1 - 6.3e-97 323.2 4.1 6.3e-97 323.2 4.1 3.0 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KXX82844.1 - 6.2e-96 320.1 6.7 1.4e-95 319.0 6.7 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KXX82844.1 - 6.1e-31 106.2 0.1 2.8e-30 104.1 0.1 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain Med14 PF08638.11 KXX82845.1 - 3.1e-62 209.4 0.0 6.3e-62 208.4 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 G6PD_C PF02781.16 KXX82846.1 - 3.1e-115 384.4 0.0 4.8e-115 383.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXX82846.1 - 2.1e-60 204.4 0.0 3.8e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain HET PF06985.11 KXX82848.1 - 2.1e-28 99.5 0.0 3.3e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VMA21 PF09446.10 KXX82849.1 - 3.9e-15 55.7 11.6 5.6e-15 55.2 11.6 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 KXX82850.1 - 6.3e-53 179.7 0.0 9.7e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXX82850.1 - 7.6e-18 64.9 0.0 5.3e-17 62.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXX82850.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_L35Ae PF01247.18 KXX82851.1 - 8.1e-42 141.3 0.3 9.1e-42 141.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KXX82851.1 - 0.00021 21.4 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.9 KXX82852.1 - 2.5e-29 101.7 0.2 6.9e-29 100.3 0.2 1.8 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) DUF3336 PF11815.8 KXX82853.1 - 3.9e-34 117.3 0.0 2.8e-32 111.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3336) Patatin PF01734.22 KXX82853.1 - 8.9e-13 48.9 1.0 1.6e-12 48.0 0.2 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase Amino_oxidase PF01593.24 KXX82855.1 - 2e-84 284.5 0.0 9.1e-71 239.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KXX82855.1 - 9.3e-15 54.7 0.0 1.8e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.19 KXX82855.1 - 1.5e-08 34.9 15.9 1.7e-08 34.8 8.3 2.9 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXX82855.1 - 2.3e-07 31.3 6.0 2.3e-07 31.3 6.0 2.3 1 1 1 2 2 2 1 HMG-box domain NAD_binding_8 PF13450.6 KXX82855.1 - 2e-06 27.9 0.0 4.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX82855.1 - 0.0029 17.3 0.1 0.044 13.4 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX82855.1 - 0.015 14.6 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ATP-synt PF00231.19 KXX82856.1 - 6.5e-80 268.8 0.4 7.9e-80 268.5 0.4 1.0 1 0 0 1 1 1 1 ATP synthase FYVE PF01363.21 KXX82857.1 - 2.4e-21 75.6 2.0 2.4e-21 75.6 2.0 3.0 4 0 0 4 4 4 1 FYVE zinc finger zf-RING_2 PF13639.6 KXX82857.1 - 1.1e-06 28.9 4.8 1.1e-06 28.9 4.8 3.7 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXX82857.1 - 1.7e-06 27.7 3.5 1.7e-06 27.7 3.5 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXX82857.1 - 6.4e-05 22.6 4.1 6.4e-05 22.6 4.1 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXX82857.1 - 0.00081 19.4 3.1 0.00081 19.4 3.1 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXX82857.1 - 0.00087 19.1 2.6 0.00087 19.1 2.6 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KXX82857.1 - 0.0045 17.2 6.8 0.0075 16.5 0.7 2.5 2 0 0 2 2 2 1 FYVE-type zinc finger Rad50_zn_hook PF04423.14 KXX82857.1 - 0.0076 16.1 2.6 0.023 14.5 0.6 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING-like PF08746.11 KXX82857.1 - 0.01 16.2 3.0 0.01 16.2 3.0 2.9 3 0 0 3 3 2 1 RING-like domain DZR PF12773.7 KXX82857.1 - 0.051 13.6 8.3 2 8.5 4.8 3.0 2 0 0 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.13 KXX82857.1 - 0.41 10.8 16.2 0.097 12.8 5.9 3.0 3 0 0 3 3 3 0 Piccolo Zn-finger Elf1 PF05129.13 KXX82857.1 - 6 7.0 14.9 1.1 9.3 2.8 3.8 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like dCMP_cyt_deam_1 PF00383.23 KXX82858.1 - 1.9e-13 50.1 0.2 2.9e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KXX82858.1 - 7.5e-08 32.7 6.8 3e-07 30.7 2.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region ABC_membrane PF00664.23 KXX82859.1 - 6.4e-90 301.5 37.8 2.6e-45 155.2 19.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXX82859.1 - 4.1e-62 208.7 4.3 1.6e-31 109.6 0.0 4.1 4 0 0 4 4 4 3 ABC transporter SMC_N PF02463.19 KXX82859.1 - 1.6e-09 37.5 11.1 0.0012 18.3 3.9 4.5 3 2 1 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXX82859.1 - 1.4e-08 34.3 0.3 0.0026 17.5 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KXX82859.1 - 1.5e-07 31.5 0.2 0.0049 16.7 0.1 3.6 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXX82859.1 - 4.4e-07 30.0 0.1 0.0065 16.4 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXX82859.1 - 8.9e-07 29.4 1.2 0.0052 17.2 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 KXX82859.1 - 1.6e-06 27.2 0.3 0.045 12.5 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KXX82859.1 - 1.9e-06 27.9 1.8 0.0033 17.2 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXX82859.1 - 5.8e-06 26.6 1.0 0.094 13.0 0.0 4.1 4 1 0 4 4 3 2 AAA domain DUF3987 PF13148.6 KXX82859.1 - 6.3e-05 22.2 0.1 0.00023 20.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_30 PF13604.6 KXX82859.1 - 0.00037 20.3 3.1 0.86 9.3 0.0 3.8 5 0 0 5 5 4 2 AAA domain AAA_25 PF13481.6 KXX82859.1 - 0.0035 17.0 0.1 2.4 7.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KXX82859.1 - 0.0041 17.1 0.3 5.5 7.0 0.0 3.3 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXX82859.1 - 0.0069 15.9 0.7 7.1 6.1 0.0 3.4 4 0 0 4 4 4 0 P-loop containing dynein motor region AAA_33 PF13671.6 KXX82859.1 - 0.0073 16.5 0.4 0.56 10.4 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXX82859.1 - 0.011 16.3 0.3 8.7 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXX82859.1 - 0.013 15.3 0.4 4.2 7.0 0.4 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXX82859.1 - 0.02 15.1 0.7 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AP3D1 PF06375.11 KXX82859.1 - 0.024 14.9 6.6 0.047 13.9 6.6 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 G-alpha PF00503.20 KXX82859.1 - 0.038 13.1 0.2 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KXX82859.1 - 0.053 13.3 0.3 3 7.6 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Baculo_11_kDa PF06143.11 KXX82859.1 - 0.074 12.6 0.1 0.074 12.6 0.1 2.4 3 0 0 3 3 1 0 Baculovirus 11 kDa family PRK PF00485.18 KXX82859.1 - 0.083 12.6 0.1 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 KXX82859.1 - 0.098 12.7 0.0 22 5.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KXX82859.1 - 0.11 12.7 9.4 1.3 9.3 0.4 4.4 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Cytomega_UL84 PF06284.11 KXX82859.1 - 0.12 10.8 0.1 0.21 10.0 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein AAA_14 PF13173.6 KXX82859.1 - 0.19 11.7 0.6 27 4.8 0.2 3.2 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 KXX82859.1 - 0.21 11.0 0.8 8.7 5.7 0.0 2.8 3 0 0 3 3 2 0 Poxvirus A32 protein Roc PF08477.13 KXX82859.1 - 1 9.6 4.8 23 5.2 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KXX82859.1 - 1.1 9.3 4.7 1.7 8.7 0.5 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KXX82859.1 - 2.1 8.8 18.2 0.34 11.4 0.5 3.3 2 1 1 3 3 2 0 AAA domain Peptidase_S49_N PF08496.10 KXX82859.1 - 3.1 7.8 7.0 3.7 7.6 1.7 3.2 3 0 0 3 3 3 0 Peptidase family S49 N-terminal tRNA-synt_His PF13393.6 KXX82860.1 - 5.7e-31 107.9 0.0 1e-24 87.4 0.0 2.5 2 1 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KXX82860.1 - 7e-12 45.3 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KXX82860.1 - 0.0028 17.2 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs DUF2681 PF10883.8 KXX82861.1 - 0.012 16.0 6.4 0.022 15.2 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Pkinase PF00069.25 KXX82862.1 - 8.1e-70 235.2 0.0 1.1e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX82862.1 - 1.7e-33 116.0 0.1 3.4e-33 115.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX82862.1 - 4.2e-06 26.3 0.0 5.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 KXX82862.1 - 0.00032 20.3 0.1 0.0027 17.3 0.1 2.3 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KXX82862.1 - 0.00041 19.8 0.2 0.00099 18.5 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXX82862.1 - 0.0024 16.7 0.1 0.006 15.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase TetR_C_27 PF17935.1 KXX82862.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UQ_con PF00179.26 KXX82863.1 - 5.1e-27 94.2 0.0 5.9e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX82863.1 - 4.6e-06 26.4 0.0 6.3e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXX82863.1 - 0.012 15.4 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KXX82863.1 - 0.073 13.4 0.1 0.098 12.9 0.1 1.4 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 KXX82863.1 - 0.18 11.4 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Sec1 PF00995.23 KXX82864.1 - 4.5e-128 429.0 0.0 5.1e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TPK_B1_binding PF04265.14 KXX82865.1 - 7.6e-26 89.6 0.0 1.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.16 KXX82865.1 - 7.1e-20 71.3 0.0 3.7e-19 69.0 0.0 1.9 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF1279 PF06916.13 KXX82866.1 - 2.3e-26 92.2 0.0 3.7e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WD40 PF00400.32 KXX82867.1 - 1.9e-26 91.8 12.9 9.1e-09 35.8 1.2 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.12 KXX82867.1 - 3.4e-23 82.4 0.1 6.5e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KXX82867.1 - 1.3e-13 51.0 2.5 1.7e-05 25.1 0.6 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXX82867.1 - 3.6e-05 22.9 0.3 0.62 9.0 0.0 3.2 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXX82867.1 - 0.00019 20.2 2.1 0.85 8.2 0.4 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 AAA_16 PF13191.6 KXX82867.1 - 0.0024 18.3 0.0 0.006 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KXX82867.1 - 0.024 15.0 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PD40 PF07676.12 KXX82867.1 - 0.056 13.4 0.6 37 4.4 0.1 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.22 KXX82867.1 - 0.13 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 KXX82867.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Gemini_mov PF01708.16 KXX82868.1 - 0.072 12.9 1.4 0.13 12.0 1.4 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein AA_permease_2 PF13520.6 KXX82869.1 - 1e-76 258.5 28.3 1.2e-76 258.2 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXX82869.1 - 1.2e-14 53.8 28.3 3.3e-14 52.4 28.3 1.7 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KXX82869.1 - 0.00083 18.2 5.8 0.00083 18.2 5.8 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein V-SNARE_C PF12352.8 KXX82870.1 - 2.4e-14 53.3 0.5 2.4e-14 53.3 0.5 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXX82870.1 - 8e-05 22.5 0.0 0.00026 20.9 0.0 1.8 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 KXX82870.1 - 0.0053 16.2 0.1 0.0086 15.5 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Sigma70_r4 PF04545.16 KXX82870.1 - 0.0061 16.1 0.2 0.014 14.9 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 KxDL PF10241.9 KXX82870.1 - 0.014 15.6 1.0 4.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein JAKMIP_CC3 PF16034.5 KXX82870.1 - 0.044 13.7 0.0 0.083 12.8 0.0 1.4 1 1 0 1 1 1 0 JAKMIP CC3 domain Mito_fiss_reg PF05308.11 KXX82870.1 - 0.092 12.8 1.0 0.14 12.2 0.9 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator HTH_DeoR PF08220.12 KXX82870.1 - 0.11 12.2 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain TPR_MLP1_2 PF07926.12 KXX82870.1 - 0.13 12.3 5.8 0.36 10.9 1.6 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 KXX82870.1 - 0.15 11.8 3.4 0.47 10.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Allexi_40kDa PF05549.11 KXX82870.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DivIC PF04977.15 KXX82870.1 - 0.18 11.6 2.6 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF2721 PF11026.8 KXX82870.1 - 1.2 9.1 3.3 9.6 6.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) E1-E2_ATPase PF00122.20 KXX82871.1 - 1.5e-18 67.0 0.0 3.7e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXX82871.1 - 6e-15 56.1 2.8 1.1e-08 35.6 3.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXX82871.1 - 0.0024 17.7 1.2 0.038 13.7 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXX82871.1 - 0.003 17.6 2.4 0.0035 17.4 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) S6PP PF05116.13 KXX82871.1 - 0.028 14.0 0.4 1.9 8.0 0.0 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase TRAP-gamma PF07074.12 KXX82871.1 - 0.18 11.3 3.8 0.51 9.9 3.8 1.8 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4059 PF13268.6 KXX82871.1 - 0.8 10.2 5.2 9.6 6.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Whi5 PF08528.11 KXX82873.1 - 1.7e-11 43.5 0.0 3.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Whi5 like Aldo_ket_red PF00248.21 KXX82875.1 - 3.7e-62 210.2 0.0 4.1e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NMO PF03060.15 KXX82877.1 - 5.8e-29 101.5 11.4 1.9e-23 83.4 7.6 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KXX82877.1 - 3.8e-09 36.0 0.3 0.0034 16.4 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXX82877.1 - 2.7e-05 23.4 3.5 4.5e-05 22.7 3.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase UCH PF00443.29 KXX82878.1 - 1.6e-43 149.1 0.1 8.2e-42 143.5 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX82878.1 - 8.5e-18 65.0 0.0 8.5e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase GvpL_GvpF PF06386.11 KXX82878.1 - 0.54 10.1 10.3 1.1 9.1 10.3 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Hamartin PF04388.12 KXX82878.1 - 0.7 8.5 21.9 1.1 7.8 21.9 1.2 1 0 0 1 1 1 0 Hamartin protein DUF737 PF05300.11 KXX82878.1 - 0.73 10.2 25.4 0.022 15.1 17.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Sec61_beta PF03911.16 KXX82879.1 - 3.1e-19 68.7 1.9 4e-19 68.4 1.9 1.2 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.12 KXX82879.1 - 0.02 15.3 2.6 0.024 15.1 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NIF PF03031.18 KXX82880.1 - 1e-53 181.3 0.1 1.3e-53 180.9 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.15 KXX82881.1 - 1e-92 310.3 2.2 8.2e-92 307.4 0.1 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXX82881.1 - 6.6e-16 59.1 0.1 2.6e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.12 KXX82881.1 - 0.015 15.0 0.0 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX82881.1 - 0.029 14.8 0.0 0.12 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXX82881.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ALIX_LYPXL_bnd PF13949.6 KXX82881.1 - 0.075 12.3 10.8 0.046 13.0 8.9 1.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV AAA_21 PF13304.6 KXX82881.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 KXX82881.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KXX82881.1 - 0.096 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXX82881.1 - 0.11 11.9 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 KXX82881.1 - 1.8 7.9 3.9 12 5.2 0.0 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_11 PF13086.6 KXX82881.1 - 3.2 7.4 9.0 1.2e+02 2.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 KXX82882.1 - 3e-12 47.6 1.9 3e-12 47.6 1.9 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX82882.1 - 3.5e-08 33.0 0.0 8.9e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXX82882.1 - 1.3e-07 31.7 0.4 2.4e-07 30.8 0.2 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXX82882.1 - 2e-06 27.7 0.1 2.6e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX82882.1 - 0.0058 16.1 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXX82882.1 - 0.062 13.1 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.25 KXX82883.1 - 8.2e-66 222.1 0.1 9.7e-66 221.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX82883.1 - 2e-19 69.9 0.0 2.8e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXX82883.1 - 1.4e-08 35.0 0.0 5.1e-06 26.6 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXX82883.1 - 0.0085 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXX82883.1 - 0.025 13.9 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXX82883.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KXX82883.1 - 0.042 13.4 1.4 0.055 13.1 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase PP2C PF00481.21 KXX82884.1 - 2.4e-57 194.5 0.0 3.8e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KXX82884.1 - 6e-42 141.2 63.2 4.7e-12 45.5 0.8 10.0 5 3 6 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 KXX82884.1 - 2.6e-34 116.7 66.0 0.00018 21.8 2.3 11.6 9 3 2 12 12 12 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KXX82884.1 - 5e-27 94.7 0.0 1.7e-26 92.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 KXX82884.1 - 7.4e-23 80.0 3.6 7.4e-23 80.0 3.6 2.3 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 KXX82884.1 - 2.2e-05 24.4 51.3 3.5 8.5 0.0 16.5 17 2 0 17 17 17 3 Leucine Rich Repeat LRR_9 PF14580.6 KXX82884.1 - 0.00036 20.1 20.6 0.07 12.6 1.3 5.1 2 1 3 5 5 5 3 Leucine-rich repeat Yos1 PF08571.10 KXX82885.1 - 1.6e-32 111.6 0.2 1.7e-32 111.5 0.2 1.0 1 0 0 1 1 1 1 Yos1-like Aldo_ket_red PF00248.21 KXX82886.1 - 1e-41 143.1 0.0 1.2e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 KXX82887.1 - 1.9e-35 120.3 22.3 2.8e-07 30.8 0.2 6.1 5 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXX82887.1 - 7.6e-23 80.1 26.6 2.4e-07 30.4 0.9 5.4 4 2 2 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 KXX82887.1 - 3.7e-17 62.4 19.4 3e-06 26.8 2.3 3.5 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 KXX82887.1 - 9.7e-05 22.1 21.1 0.86 9.8 0.2 8.1 10 1 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.33 KXX82887.1 - 0.012 16.0 25.5 9.7 7.2 0.3 8.0 7 2 0 7 7 7 0 Leucine Rich Repeat T4bSS_IcmS PF12608.8 KXX82887.1 - 0.07 13.4 0.6 0.14 12.5 0.6 1.4 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment FAD_binding_4 PF01565.23 KXX82888.1 - 3.3e-26 91.7 1.4 1.2e-25 89.9 1.3 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXX82888.1 - 7e-07 29.3 0.5 1.4e-06 28.3 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KXX82889.1 - 1.6e-31 109.6 0.0 3.4e-21 75.5 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 adh_short PF00106.25 KXX82890.1 - 2.8e-31 108.5 0.1 3.7e-31 108.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82890.1 - 6.9e-25 88.0 0.1 8.7e-25 87.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82890.1 - 3.7e-08 33.5 0.2 4.7e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX82890.1 - 1.8e-06 27.6 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXX82890.1 - 0.00055 19.9 0.8 0.0012 18.8 0.8 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXX82890.1 - 0.056 12.8 0.0 5.1 6.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KXX82891.1 - 8.5e-07 28.3 0.1 1.3e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KXX82892.1 - 2.4e-54 184.8 0.0 1.3e-53 182.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 KXX82893.1 - 0.00013 21.5 0.0 0.00015 21.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease NIF PF03031.18 KXX82895.1 - 1.9e-38 131.7 0.0 2.7e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Suf PF05843.14 KXX82895.1 - 2.5 8.0 7.2 5 7.0 7.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Fungal_trans PF04082.18 KXX82897.1 - 1.1e-09 37.8 0.0 1.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82897.1 - 1e-07 31.9 7.5 2.2e-07 30.9 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CGI-121 PF08617.10 KXX82898.1 - 1.4e-49 168.3 0.0 1.6e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Zeta_toxin PF06414.12 KXX82898.1 - 0.13 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Pro_dh PF01619.18 KXX82899.1 - 2.7e-72 243.8 0.0 3.3e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase bZIP_2 PF07716.15 KXX82899.1 - 0.18 11.9 2.0 0.36 10.9 2.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF3176 PF11374.8 KXX82901.1 - 3.6e-31 107.5 0.0 1.1e-30 106.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) adh_short PF00106.25 KXX82902.1 - 2.7e-28 98.7 0.1 3.8e-26 91.7 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX82902.1 - 2.6e-19 69.7 0.0 4.9e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX82902.1 - 4e-07 30.1 0.1 1.7e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX82902.1 - 2.8e-05 23.7 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KXX82902.1 - 0.013 16.1 0.1 0.029 14.9 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXX82902.1 - 0.03 13.7 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KXX82902.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KXX82902.1 - 0.17 11.4 0.1 0.39 10.3 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family Methyltransf_2 PF00891.18 KXX82903.1 - 2e-20 73.0 0.0 3.6e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXX82903.1 - 2.9e-06 27.9 0.0 1.5e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82903.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXX82903.1 - 0.00033 20.2 0.0 0.00063 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KXX82903.1 - 0.018 15.8 0.0 0.041 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Receptor_IA-2 PF11548.8 KXX82903.1 - 0.089 12.8 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 Ubie_methyltran PF01209.18 KXX82903.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PS-DH PF14765.6 KXX82904.1 - 4.9e-78 262.4 0.0 8.7e-78 261.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KXX82904.1 - 2e-67 227.5 0.0 4.1e-67 226.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX82904.1 - 2.4e-51 174.2 0.3 5.6e-51 173.0 0.3 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXX82904.1 - 2.4e-49 168.6 0.1 5.5e-49 167.4 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX82904.1 - 3.1e-35 120.7 0.5 9.5e-35 119.2 0.1 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXX82904.1 - 2.2e-20 73.2 0.0 9.4e-19 68.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXX82904.1 - 2.4e-19 69.8 0.6 2.8e-13 50.3 0.1 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KXX82904.1 - 3.9e-13 49.6 0.0 2e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82904.1 - 7.4e-12 45.8 0.0 8.4e-11 42.4 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82904.1 - 1.2e-10 41.9 0.0 7.9e-10 39.3 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82904.1 - 6.7e-10 39.0 0.0 6.2e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KXX82904.1 - 3.7e-08 33.1 3.8 1.1e-07 31.5 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KXX82904.1 - 8.5e-08 32.2 0.1 1.2e-05 25.3 0.0 3.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KXX82904.1 - 1.6e-07 31.6 0.3 5.4e-07 29.9 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 KXX82904.1 - 2.6e-06 26.8 0.0 4.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ubie_methyltran PF01209.18 KXX82904.1 - 1e-05 25.0 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KXX82904.1 - 0.00038 19.9 0.9 0.00096 18.6 0.3 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_2 PF00891.18 KXX82904.1 - 0.0022 17.3 0.0 0.0057 16.0 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain ACP_syn_III PF08545.10 KXX82904.1 - 0.0033 17.2 0.2 0.0095 15.8 0.2 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 KXX82904.1 - 0.0087 15.9 0.2 0.019 14.9 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.19 KXX82904.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MTS PF05175.14 KXX82904.1 - 0.06 12.9 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase small domain DNA_gyraseB_C PF00986.21 KXX82904.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus EccE PF11203.8 KXX82904.1 - 1.6 9.1 5.5 0.34 11.3 0.2 2.5 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Methyltransf_23 PF13489.6 KXX82905.1 - 2.2e-08 34.1 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX82905.1 - 1.1e-07 32.5 0.0 2.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82905.1 - 1.3e-06 29.0 0.0 8.1e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX82905.1 - 0.00017 21.4 0.0 0.001 18.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82905.1 - 0.02 15.5 0.0 0.063 13.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF1848 PF08902.11 KXX82905.1 - 0.061 13.0 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) CheR PF01739.18 KXX82905.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 KXX82905.1 - 0.2 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MFS_1 PF07690.16 KXX82906.1 - 1.5e-38 132.7 46.4 1.1e-36 126.5 46.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXX82906.1 - 6.7e-14 51.2 17.5 2.1e-13 49.6 17.4 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CENP-B_dimeris PF09026.10 KXX82906.1 - 0.079 13.4 0.3 0.18 12.2 0.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RhoGAP PF00620.27 KXX82908.1 - 1.1e-15 57.8 0.0 2.4e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain Helo_like_N PF17111.5 KXX82908.1 - 1.8e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Methyltransf_31 PF13847.6 KXX82909.1 - 1.2e-05 25.2 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX82909.1 - 2.6e-05 24.8 0.0 4.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX82909.1 - 4.1e-05 24.1 0.0 6.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX82909.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX82909.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PTS_2-RNA PF01885.16 KXX82910.1 - 1.8e-23 83.6 0.0 2.4e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF4939 PF16297.5 KXX82910.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) 6PGD PF00393.19 KXX82911.1 - 1.7e-93 313.2 0.0 2.2e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXX82911.1 - 8.7e-30 104.0 0.1 2.4e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KXX82911.1 - 0.0023 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KXX82911.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AP_endonuc_2 PF01261.24 KXX82912.1 - 1.4e-38 132.5 0.0 2.1e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 KXX82912.1 - 0.068 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus HET PF06985.11 KXX82913.1 - 3.7e-29 102.0 0.0 1.3e-28 100.2 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ricin_B_lectin PF00652.22 KXX82914.1 - 1.9e-16 60.5 5.5 2.3e-09 37.6 0.3 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KXX82914.1 - 1.9e-09 38.1 3.7 1.7e-06 28.7 0.5 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like WD40 PF00400.32 KXX82916.1 - 3.5e-07 30.8 9.5 0.57 11.2 0.5 6.1 6 1 0 6 6 6 3 WD domain, G-beta repeat MtaB PF12176.8 KXX82916.1 - 0.031 13.1 0.2 0.046 12.5 0.2 1.2 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit ATP-synt_E PF05680.12 KXX82917.1 - 1.3e-25 89.6 0.7 1.4e-25 89.4 0.7 1.0 1 0 0 1 1 1 1 ATP synthase E chain SYF2 PF08231.12 KXX82917.1 - 0.035 14.5 1.6 0.041 14.3 1.6 1.2 1 0 0 1 1 1 0 SYF2 splicing factor tRNA-synt_1d PF00750.19 KXX82919.1 - 1.4e-90 303.8 0.4 2.4e-90 303.0 0.4 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) Acetyltransf_3 PF13302.7 KXX82919.1 - 1.1e-33 116.8 0.0 4.7e-33 114.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DALR_1 PF05746.15 KXX82919.1 - 3.8e-13 49.7 0.1 7.3e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arf PF00025.21 KXX82919.1 - 2e-12 46.9 0.0 9.1e-11 41.5 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Acetyltransf_1 PF00583.25 KXX82919.1 - 0.009 16.2 0.0 0.041 14.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Zn_clus PF00172.18 KXX82920.1 - 1e-09 38.3 5.7 1.7e-09 37.7 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXX82920.1 - 6.3e-05 22.1 0.0 0.0002 20.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1656 PF07869.12 KXX82921.1 - 0.089 12.8 2.6 0.14 12.2 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) SinI PF08671.10 KXX82921.1 - 0.5 10.2 3.5 0.72 9.7 1.7 2.3 2 0 0 2 2 2 0 Anti-repressor SinI Ribosomal_60s PF00428.19 KXX82921.1 - 1.5 9.5 5.8 2.1 9.0 3.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KXX82921.1 - 2 8.8 7.6 3.5 8.1 6.5 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BTB PF00651.31 KXX82922.1 - 3.6e-11 43.3 0.3 2.2e-10 40.7 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.15 KXX82922.1 - 0.0012 19.0 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Hydrolase_4 PF12146.8 KXX82923.1 - 0.00033 20.0 0.1 0.071 12.4 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DMRL_synthase PF00885.19 KXX82923.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase Ribosomal_L18A PF01775.17 KXX82924.1 - 4.2e-55 185.0 0.3 5.3e-55 184.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Stimulus_sens_1 PF13756.6 KXX82924.1 - 0.1 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Stimulus-sensing domain PCI PF01399.27 KXX82925.1 - 1.8e-12 47.7 0.0 4.9e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain HEPN_SAV_6107 PF18726.1 KXX82925.1 - 0.027 15.0 0.1 0.17 12.4 0.1 2.1 2 0 0 2 2 2 0 SAV_6107-like HEPN Glyco_hydro_45 PF02015.16 KXX82926.1 - 5.5e-74 248.6 18.5 6.6e-74 248.4 18.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Het-C PF07217.11 KXX82927.1 - 7.4e-233 774.1 0.0 9.3e-233 773.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Maf PF02545.14 KXX82928.1 - 5.8e-49 166.1 0.0 6.8e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Glyco_hydro_47 PF01532.20 KXX82929.1 - 8.5e-172 572.2 0.0 9.8e-172 571.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3791 PF12668.7 KXX82929.1 - 0.038 14.0 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Utp11 PF03998.13 KXX82930.1 - 1.7e-65 221.4 23.1 1.9e-65 221.2 23.1 1.0 1 0 0 1 1 1 1 Utp11 protein FliD_N PF02465.18 KXX82930.1 - 1.4 9.7 6.7 4.3 8.1 0.0 2.7 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SLATT_5 PF18160.1 KXX82930.1 - 3.7 6.8 7.5 0.48 9.7 0.5 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HMG_box PF00505.19 KXX82932.1 - 1.9e-06 28.2 0.1 6e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXX82932.1 - 0.00055 20.5 0.6 0.0031 18.1 0.1 2.4 2 0 0 2 2 2 1 HMG-box domain tRNA-synt_2b PF00587.25 KXX82933.1 - 1.1e-33 116.8 0.0 5.9e-32 111.1 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXX82933.1 - 3.3e-07 30.3 0.0 5.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain DUF848 PF05852.11 KXX82934.1 - 0.062 13.4 0.2 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Amidohydro_1 PF01979.20 KXX82935.1 - 1.7e-73 247.9 0.4 3e-73 247.1 0.4 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KXX82935.1 - 7.6e-56 187.7 2.8 3e-55 185.7 1.0 2.3 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KXX82935.1 - 1.3e-41 140.6 0.3 3.2e-41 139.3 0.1 1.9 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KXX82935.1 - 6.5e-37 125.8 0.0 1.5e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KXX82935.1 - 3.4e-11 43.3 0.1 9e-06 25.4 0.0 2.8 2 1 1 3 3 3 2 Amidohydrolase family PLA2_B PF01735.18 KXX82937.1 - 1.1e-192 640.9 0.0 1.2e-192 640.7 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TFIID-31kDa PF02291.15 KXX82939.1 - 1.1e-30 106.2 0.0 3.7e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit CCSAP PF15748.5 KXX82939.1 - 0.14 12.3 8.8 0.19 11.9 8.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 KXX82939.1 - 1.6 7.4 5.9 2 7.1 5.9 1.1 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 KXX82939.1 - 4.3 6.4 24.4 4.9 6.2 24.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KXX82939.1 - 6 6.7 10.9 7.8 6.3 10.9 1.2 1 0 0 1 1 1 0 SPX domain Spt20 PF12090.8 KXX82939.1 - 8.9 5.8 19.3 13 5.3 19.3 1.2 1 0 0 1 1 1 0 Spt20 family Histidinol_dh PF00815.20 KXX82940.1 - 2.5e-159 530.7 4.2 3.3e-159 530.3 4.2 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KXX82940.1 - 2.1e-23 81.9 0.1 4.2e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KXX82940.1 - 1.3e-12 48.0 1.5 4.4e-11 43.1 0.2 2.7 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Phasin_2 PF09361.10 KXX82940.1 - 0.004 17.4 0.3 0.46 10.8 0.6 3.3 3 0 0 3 3 3 1 Phasin protein fn3 PF00041.21 KXX82941.1 - 1.9e-07 31.3 0.0 5.6e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain LNS2 PF08235.13 KXX82942.1 - 1.4e-93 312.6 0.0 1.8e-93 312.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KXX82942.1 - 1.7e-42 143.5 0.0 5.2e-42 142.0 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KXX82942.1 - 0.0024 17.5 0.0 0.19 11.3 0.0 2.6 2 0 0 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) DAO PF01266.24 KXX82943.1 - 3.2e-29 102.6 0.5 4.3e-29 102.2 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX82943.1 - 1.6e-05 24.3 0.1 2.4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX82943.1 - 1.8e-05 25.2 0.2 3.6e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX82943.1 - 0.0004 19.6 0.7 0.0006 19.0 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX82943.1 - 0.00061 20.0 0.6 0.00061 20.0 0.6 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KXX82943.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KXX82943.1 - 0.0024 17.2 0.7 0.0036 16.6 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KXX82943.1 - 0.005 16.8 0.3 0.008 16.1 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXX82943.1 - 0.0075 15.6 0.5 0.011 15.0 0.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXX82943.1 - 0.01 15.1 1.1 0.017 14.4 1.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXX82943.1 - 0.028 14.9 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 KXX82943.1 - 0.039 13.0 0.1 0.054 12.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXX82943.1 - 0.078 11.7 1.5 0.11 11.2 1.5 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KXX82943.1 - 0.13 11.9 1.4 0.2 11.2 1.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KXX82943.1 - 0.15 11.3 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Cmc1 PF08583.10 KXX82944.1 - 2e-18 66.1 3.1 2e-18 66.1 3.1 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KXX82944.1 - 0.00038 20.4 0.2 0.00061 19.7 0.2 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KXX82944.1 - 0.00047 20.2 2.1 0.77 10.0 0.2 2.4 2 0 0 2 2 2 2 CHCH domain Atrophin-1 PF03154.15 KXX82944.1 - 0.11 10.7 9.1 0.17 10.1 9.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family Zn_Tnp_IS91 PF14319.6 KXX82944.1 - 0.31 11.1 3.7 0.34 11.0 2.6 1.6 2 0 0 2 2 2 0 Transposase zinc-binding domain SnoaL PF07366.12 KXX82946.1 - 5.8e-14 52.0 0.2 4e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXX82946.1 - 1.1e-05 26.0 0.2 8.9e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 SnoaL-like domain HET PF06985.11 KXX82947.1 - 5.9e-29 101.3 0.0 1.2e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KXX82948.1 - 9.3e-78 256.9 3.0 2.2e-14 53.8 0.0 7.5 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX82948.1 - 2.6e-66 219.2 6.5 8e-09 35.9 0.1 9.0 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KXX82948.1 - 3.4e-65 213.8 10.3 7.8e-06 26.1 0.0 13.7 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 KXX82948.1 - 3.8e-64 205.0 3.2 9.7e-06 25.6 0.0 13.7 13 0 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.6 KXX82948.1 - 3.3e-53 177.1 18.4 8.3e-06 26.0 0.1 12.1 2 2 11 13 13 13 11 Ankyrin repeats (many copies) Peptidase_S8 PF00082.22 KXX82948.1 - 1.3e-13 50.9 0.6 1.8e-12 47.2 0.6 2.4 1 1 0 1 1 1 1 Subtilase family Polyoma_agno PF01736.16 KXX82948.1 - 0.029 14.1 0.0 2.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Polyomavirus agnoprotein DUF2789 PF10982.8 KXX82948.1 - 0.069 13.3 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) 3-dmu-9_3-mt PF06983.13 KXX82949.1 - 6.1e-48 162.2 0.3 7.9e-48 161.8 0.3 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase NCD1 PF04904.13 KXX82949.1 - 0.08 13.0 0.0 20 5.3 0.0 2.4 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) FAD_binding_4 PF01565.23 KXX82951.1 - 7.2e-28 97.1 0.4 1.2e-27 96.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Tyrosinase PF00264.20 KXX82952.1 - 1.3e-44 153.1 0.0 2e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_C1 PF00112.23 KXX82953.1 - 5.5e-27 95.3 1.0 9.7e-27 94.5 1.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Flavin_Reduct PF01613.18 KXX82954.1 - 1.5e-13 51.1 0.0 2.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain TPP_enzyme_N PF02776.18 KXX82957.1 - 3.9e-33 114.5 5.8 1.2e-31 109.7 0.2 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXX82957.1 - 2.1e-17 63.3 0.3 7.8e-17 61.5 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXX82957.1 - 3.7e-05 23.5 0.0 0.0001 22.0 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AhpC-TSA PF00578.21 KXX82958.1 - 1.6e-07 31.2 0.0 3e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXX82958.1 - 0.00093 18.9 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KXX82958.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Pkinase PF00069.25 KXX82959.1 - 6.8e-47 160.0 0.0 8.1e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX82959.1 - 2.1e-25 89.5 0.0 2.6e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXX82959.1 - 2.7e-07 30.2 0.0 3.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXX82959.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXX82959.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KXX82960.1 - 4e-06 26.3 0.1 2.6e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXX82960.1 - 7.7e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DUF1363 PF07101.11 KXX82962.1 - 0.0022 18.3 0.0 0.0022 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1363) MFS_1 PF07690.16 KXX82963.1 - 1e-28 100.3 37.9 1.3e-28 100.0 37.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2964 PF11177.8 KXX82963.1 - 1.4 9.1 4.6 25 5.2 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2964) p450 PF00067.22 KXX82964.1 - 2.2e-59 201.4 0.0 3e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 XK-related PF09815.9 KXX82964.1 - 0.57 9.2 3.0 0.82 8.7 3.0 1.2 1 0 0 1 1 1 0 XK-related protein Trypsin_2 PF13365.6 KXX82967.1 - 8.2e-28 98.2 0.1 1.2e-27 97.7 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 KXX82967.1 - 0.025 13.2 0.0 0.3 9.7 0.1 2.0 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.13 KXX82967.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_C4 PF00863.19 KXX82967.1 - 0.14 11.4 0.0 0.56 9.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C4 CorA PF01544.18 KXX82968.1 - 2.3e-21 76.4 9.1 1.8e-18 66.9 5.3 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Zn_clus PF00172.18 KXX82969.1 - 9.9e-08 32.0 9.7 2e-07 31.0 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoD PF09423.10 KXX82971.1 - 1.1e-105 353.5 3.1 1.5e-105 353.1 3.1 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KXX82971.1 - 1.5e-31 108.8 0.2 3.7e-31 107.5 0.2 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KXX82971.1 - 4.8e-05 23.9 3.2 0.00019 21.9 3.3 2.0 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain MFS_1 PF07690.16 KXX82972.1 - 3.8e-28 98.4 22.2 4.9e-28 98.1 22.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX82972.1 - 5.2e-15 55.3 8.0 1.2e-14 54.0 7.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXX82972.1 - 3e-09 35.9 4.4 4.4e-09 35.3 4.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EMP70 PF02990.16 KXX82972.1 - 0.018 13.7 1.0 0.032 12.9 0.1 1.8 2 1 1 3 3 3 0 Endomembrane protein 70 MFS_1 PF07690.16 KXX82973.1 - 7.7e-38 130.3 29.9 1.8e-37 129.1 30.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXX82973.1 - 0.0013 17.7 7.7 0.0028 16.6 6.6 1.9 1 1 0 1 1 1 1 MFS_1 like family ASFV_J13L PF05568.11 KXX82974.1 - 0.24 11.1 0.7 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF202 PF02656.15 KXX82974.1 - 4.8 7.7 13.6 47 4.5 0.7 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Abhydrolase_6 PF12697.7 KXX82976.1 - 5.7e-05 23.8 0.0 6.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXX82976.1 - 0.033 13.7 0.0 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF2855 PF11017.8 KXX82977.1 - 7.2e-71 239.7 0.0 8.5e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) HET PF06985.11 KXX82978.1 - 2.8e-10 40.7 7.5 2.8e-08 34.3 1.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF676 PF05057.14 KXX82979.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXX82979.1 - 3.8e-05 23.5 0.0 5.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.22 KXX82979.1 - 0.00038 20.5 0.0 0.00054 20.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF829 PF05705.14 KXX82979.1 - 0.00053 19.9 0.0 0.00071 19.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.7 KXX82979.1 - 0.004 17.8 0.0 0.021 15.4 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.9 KXX82979.1 - 0.0079 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family DUF726 PF05277.12 KXX82979.1 - 0.01 14.8 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Lipase_3 PF01764.25 KXX82979.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 KXX82979.1 - 0.028 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KXX82979.1 - 0.033 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Palm_thioest PF02089.15 KXX82979.1 - 0.043 13.6 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase HPP PF04982.13 KXX82981.1 - 2.7e-26 92.1 8.7 5.3e-26 91.2 8.6 1.5 1 1 0 1 1 1 1 HPP family FAD_binding_4 PF01565.23 KXX82982.1 - 4.5e-20 71.8 1.1 4.5e-20 71.8 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXX82982.1 - 1e-09 38.3 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Aminotran_5 PF00266.19 KXX82983.1 - 2.3e-07 30.1 0.0 3.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXX82983.1 - 0.086 11.4 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXX82983.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.18 KXX82984.1 - 6.8e-152 506.2 0.0 7.7e-152 506.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CAF1C_H4-bd PF12265.8 KXX82985.1 - 1.2e-13 51.0 0.0 5.3e-13 49.0 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXX82985.1 - 2.6e-13 50.2 8.4 1.7e-06 28.6 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX82985.1 - 2.6e-06 27.6 0.1 0.03 14.6 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain O-FucT PF10250.9 KXX82986.1 - 8.6e-25 88.1 0.0 1.7e-24 87.2 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3445 PF11927.8 KXX82987.1 - 2.3e-45 155.0 0.0 6.3e-45 153.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) MKRN1_C PF15815.5 KXX82987.1 - 0.13 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal DUF2286 PF10051.9 KXX82987.1 - 0.19 11.4 0.5 0.31 10.8 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) HET PF06985.11 KXX82988.1 - 2.4e-20 73.4 0.1 5.1e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Arg_decarb_HB PF17810.1 KXX82988.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain Peptidase_S8 PF00082.22 KXX82989.1 - 7.1e-06 25.5 0.2 0.058 12.7 0.0 2.8 2 1 0 2 2 2 2 Subtilase family ThrE PF06738.12 KXX82989.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter FAD_binding_4 PF01565.23 KXX82991.1 - 3.8e-27 94.7 2.7 3.8e-27 94.7 2.7 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXX82991.1 - 3.8e-06 26.9 0.2 7.5e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like AAA_12 PF13087.6 KXX82993.1 - 8.9e-29 100.5 0.0 2.3e-28 99.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXX82993.1 - 2e-18 67.2 3.1 1.9e-11 44.3 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KXX82993.1 - 1.9e-07 31.0 0.0 8.8e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX82993.1 - 5.9e-07 29.9 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KXX82993.1 - 0.00041 20.0 0.0 0.00086 18.9 0.0 1.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KXX82993.1 - 0.00058 19.9 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXX82993.1 - 0.0013 18.6 0.0 0.13 12.1 0.0 2.8 3 0 0 3 3 3 1 Helicase DUF2075 PF09848.9 KXX82993.1 - 0.0027 17.0 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KXX82993.1 - 0.0029 17.9 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXX82993.1 - 0.022 15.2 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXX82993.1 - 0.052 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.18 KXX82993.1 - 0.069 12.9 0.0 4.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CDC45 PF02724.14 KXX82994.1 - 3.6 5.7 5.5 4 5.6 5.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Keratin_2_head PF16208.5 KXX82994.1 - 5.3 7.2 19.4 7.2 6.7 19.4 1.1 1 0 0 1 1 1 0 Keratin type II head API5 PF05918.11 KXX82994.1 - 7.2 5.3 14.6 8.2 5.1 14.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1524 PF07510.11 KXX82995.1 - 8.1e-06 25.8 0.0 9.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) PGAP1 PF07819.13 KXX82996.1 - 6.5e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 KXX82996.1 - 0.0034 17.0 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KXX82996.1 - 0.048 14.3 0.3 0.12 13.0 0.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 KXX82996.1 - 0.062 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ank_2 PF12796.7 KXX82997.1 - 4e-68 226.0 0.1 2.1e-09 37.8 0.0 10.1 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX82997.1 - 3e-50 168.0 5.7 1.2e-07 32.2 0.0 12.4 9 4 4 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX82997.1 - 1.3e-46 151.2 2.2 0.00091 19.5 0.0 15.3 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.6 KXX82997.1 - 1.3e-45 152.9 6.9 0.0014 18.9 0.0 13.4 9 3 4 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 KXX82997.1 - 4e-45 150.4 3.5 0.00042 20.6 0.0 14.5 15 0 0 15 15 15 11 Ankyrin repeat Fungal_trans PF04082.18 KXX82999.1 - 3.5e-12 45.9 0.0 7.8e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX82999.1 - 0.00012 22.2 8.1 0.00012 22.2 8.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lenti_VIF_2 PF07401.12 KXX82999.1 - 0.036 13.4 0.2 0.22 10.9 0.0 2.2 3 0 0 3 3 3 0 Bovine Lentivirus VIF protein Kelch_6 PF13964.6 KXX83000.1 - 1.3e-13 50.7 8.8 0.00045 20.4 0.2 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KXX83000.1 - 6.7e-13 48.4 12.1 0.0018 18.2 0.2 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXX83000.1 - 1.6e-10 40.7 8.7 0.0028 17.6 0.0 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 KXX83000.1 - 3.7e-10 39.2 5.8 0.17 11.5 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KXX83000.1 - 4.9e-05 23.1 3.4 0.65 10.1 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KXX83000.1 - 0.00036 20.8 15.1 0.017 15.4 0.3 5.3 6 0 0 6 6 6 3 Galactose oxidase, central domain p450 PF00067.22 KXX83001.1 - 2.5e-63 214.4 0.0 7.3e-62 209.6 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 SnoaL_2 PF12680.7 KXX83002.1 - 1.3e-05 25.7 0.0 2.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain RdRP PF05183.12 KXX83003.1 - 2.9e-88 297.0 0.0 3.5e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase EAL PF00563.20 KXX83003.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 EAL domain RdRP PF05183.12 KXX83004.1 - 8.7e-45 153.4 0.0 1.2e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KXX83004.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ILVD_EDD PF00920.21 KXX83005.1 - 4.3e-208 692.1 2.0 4.9e-208 691.9 2.0 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_15 PF01793.16 KXX83006.1 - 4.2e-96 322.0 8.7 4.2e-95 318.7 8.7 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PadR PF03551.14 KXX83006.1 - 0.03 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Myb_DNA-binding PF00249.31 KXX83007.1 - 1.3e-16 60.5 1.8 2.5e-09 37.2 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXX83007.1 - 3.8e-09 36.7 0.5 0.00029 21.0 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXX83008.1 - 0.0011 19.1 0.1 0.011 15.9 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.21 KXX83010.1 - 5.2e-46 156.3 1.9 9.2e-46 155.5 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KXX83010.1 - 9.9 6.7 17.0 0.47 11.0 11.0 1.9 2 0 0 2 2 2 0 Chitin recognition protein PhzC-PhzF PF02567.16 KXX83011.1 - 1.5e-40 139.5 0.0 2.5e-40 138.7 0.0 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein zf-RING_UBOX PF13445.6 KXX83013.1 - 0.00081 19.4 0.7 0.0018 18.3 0.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXX83013.1 - 0.0012 18.6 2.7 0.0089 15.9 0.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXX83013.1 - 0.0019 18.1 3.0 0.0063 16.4 3.1 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXX83013.1 - 0.013 15.3 0.9 0.013 15.3 0.9 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXX83013.1 - 0.041 13.8 3.2 0.063 13.2 0.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXX83013.1 - 0.14 12.4 1.3 1.4 9.2 0.6 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KXX83013.1 - 0.15 12.2 1.2 0.36 11.0 0.2 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 KXX83013.1 - 0.33 11.3 4.5 0.19 12.1 1.5 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 KXX83013.1 - 2 8.4 6.2 5.1 7.1 6.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prp19 PF08606.11 KXX83014.1 - 6.6e-31 106.1 2.3 6.6e-31 106.1 2.3 1.9 2 0 0 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KXX83014.1 - 1.8e-10 41.0 0.0 0.014 15.7 0.0 5.2 1 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXX83014.1 - 4.6e-10 39.9 0.8 0.059 14.3 0.0 5.6 5 1 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 KXX83014.1 - 8.2e-05 22.6 0.0 0.011 15.7 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KXX83014.1 - 0.00062 18.9 0.0 0.0074 15.4 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region V_ATPase_I_N PF18670.1 KXX83014.1 - 0.007 16.7 0.6 0.017 15.5 0.6 1.6 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 KXX83014.1 - 0.0074 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mcl1_mid PF12341.8 KXX83014.1 - 0.011 15.1 0.1 0.38 10.0 0.0 2.2 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region WD40_like PF17005.5 KXX83014.1 - 0.021 14.2 0.0 0.21 10.8 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain Sun2_CC2 PF18580.1 KXX83014.1 - 0.69 10.2 3.0 5.4 7.3 0.2 3.2 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 Raptor_N PF14538.6 KXX83016.1 - 0.13 12.2 0.2 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain SR-25 PF10500.9 KXX83016.1 - 4.5 6.8 12.8 8.4 5.9 12.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.19 KXX83017.1 - 7.7e-11 41.8 0.3 0.001 18.4 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXX83017.1 - 1.6e-05 25.0 0.2 3.2e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX83017.1 - 0.0015 18.1 0.1 0.027 14.1 0.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX83017.1 - 0.0043 16.3 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXX83017.1 - 0.0055 17.2 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXX83017.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TPD52 PF04201.15 KXX83018.1 - 0.42 10.2 4.3 0.72 9.5 4.3 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Abhydrolase_4 PF08386.10 KXX83019.1 - 1.6e-21 76.3 0.0 3.2e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXX83019.1 - 1.5e-19 70.6 0.0 4.4e-16 59.3 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold APH PF01636.23 KXX83020.1 - 4.6e-13 49.7 0.1 9.7e-13 48.6 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXX83020.1 - 0.0012 18.2 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXX83020.1 - 0.022 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CBM_19 PF03427.13 KXX83021.1 - 0.57 10.2 8.6 2.1 8.4 8.6 2.0 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) TFIIA PF03153.13 KXX83022.1 - 0.0062 16.6 8.4 0.0089 16.1 8.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 KXX83022.1 - 0.026 14.5 16.9 0.032 14.1 16.9 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KXX83022.1 - 4.8 6.3 19.4 7.1 5.7 19.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M49 PF03571.15 KXX83023.1 - 1.9e-237 789.0 0.0 2.3e-237 788.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 KXX83023.1 - 0.036 14.2 0.3 0.085 13.0 0.3 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain SKI PF01202.22 KXX83024.1 - 4.6e-14 52.9 0.0 6.1e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KXX83024.1 - 5.3e-10 39.9 0.0 1.2e-09 38.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXX83024.1 - 1.5e-07 31.7 0.0 2.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXX83024.1 - 2.2e-06 28.2 0.0 1.3e-05 25.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KXX83024.1 - 1.4e-05 24.9 0.0 3.6e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 KXX83024.1 - 1.6e-05 24.9 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXX83024.1 - 5.8e-05 23.5 0.0 7e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXX83024.1 - 0.00042 20.7 0.1 0.0076 16.7 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KXX83024.1 - 0.00043 20.2 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase APS_kinase PF01583.20 KXX83024.1 - 0.00084 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT PF05729.12 KXX83024.1 - 0.0011 19.0 0.0 0.0043 17.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXX83024.1 - 0.0011 19.2 0.0 0.0022 18.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KXX83024.1 - 0.0014 19.0 0.0 0.0035 17.7 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.21 KXX83024.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXX83024.1 - 0.0029 17.6 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXX83024.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXX83024.1 - 0.006 17.1 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.17 KXX83024.1 - 0.0068 16.1 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase CoaE PF01121.20 KXX83024.1 - 0.01 15.5 0.0 0.091 12.4 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase PRK PF00485.18 KXX83024.1 - 0.016 15.0 0.0 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 KXX83024.1 - 0.017 15.0 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 KXX83024.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXX83024.1 - 0.021 14.7 0.1 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Cytidylate_kin2 PF13189.6 KXX83024.1 - 0.023 14.8 0.0 0.18 12.0 0.0 2.1 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_29 PF13555.6 KXX83024.1 - 0.028 14.2 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KXX83024.1 - 0.039 14.0 0.0 0.095 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXX83024.1 - 0.065 13.7 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXX83024.1 - 0.082 12.6 0.1 0.24 11.1 0.0 1.6 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 KXX83024.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KXX83024.1 - 0.086 12.1 0.1 0.33 10.2 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KXX83024.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KXX83024.1 - 0.099 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KXX83024.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 KXX83024.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain NB-ARC PF00931.22 KXX83024.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SVIP PF15811.5 KXX83025.1 - 1.2 9.7 12.8 3.1 8.3 12.8 1.7 1 1 0 1 1 1 0 Small VCP/p97-interacting protein zf-C2H2 PF00096.26 KXX83026.1 - 2.9e-27 93.6 35.5 2.5e-05 24.5 0.7 7.9 7 1 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX83026.1 - 3e-22 78.0 26.6 7.3e-07 29.3 0.1 6.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX83026.1 - 2.4e-18 65.2 30.6 0.00034 21.2 0.6 8.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXX83026.1 - 9.7e-13 47.8 21.2 0.012 15.6 0.6 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX83026.1 - 6.6e-11 42.2 14.1 0.061 13.6 0.0 5.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KXX83026.1 - 0.0004 20.6 27.4 0.16 12.3 3.8 6.1 5 1 1 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KXX83026.1 - 0.023 14.5 9.2 0.5 10.3 0.3 3.9 4 0 0 4 4 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KXX83026.1 - 0.03 14.2 9.9 2.2 8.2 0.3 4.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type ZF-HD_dimer PF04770.12 KXX83026.1 - 0.04 14.3 0.8 0.04 14.3 0.8 2.7 3 0 0 3 3 3 0 ZF-HD protein dimerisation region Rad50_zn_hook PF04423.14 KXX83026.1 - 0.044 13.6 0.7 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 KXX83026.1 - 0.18 12.1 18.4 0.69 10.3 0.9 5.1 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 KXX83026.1 - 0.31 11.5 20.7 0.91 10.0 0.1 6.0 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zf-met PF12874.7 KXX83026.1 - 0.67 10.4 24.8 0.86 10.1 0.6 6.2 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 KXX83026.1 - 2.6 8.4 13.9 4.3 7.7 0.1 4.6 4 0 0 4 4 4 0 zinc-ribbon zf-H2C2_5 PF13909.6 KXX83026.1 - 2.8 7.8 18.7 3.9 7.3 1.7 5.5 5 0 0 5 5 5 0 C2H2-type zinc-finger domain HC2 PF07382.11 KXX83028.1 - 1.1e-05 25.6 27.4 1.1e-05 25.6 27.4 1.7 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 DAO PF01266.24 KXX83028.1 - 0.082 12.5 0.5 0.12 11.9 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1682 PF07946.14 KXX83028.1 - 1.6 7.9 19.1 2.9 7.0 19.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Dynamin_N PF00350.23 KXX83029.1 - 3.3e-24 85.8 0.0 3.9e-23 82.3 0.0 2.7 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXX83029.1 - 1.2e-09 37.8 2.0 2e-08 33.8 0.1 2.6 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 KXX83029.1 - 0.0025 17.9 0.0 0.038 14.1 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KXX83029.1 - 0.003 17.7 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.27 KXX83029.1 - 0.035 14.6 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 KXX83029.1 - 0.041 14.1 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 KXX83029.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXX83029.1 - 0.052 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXX83029.1 - 0.14 12.6 1.2 0.61 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Latarcin PF10279.9 KXX83029.1 - 2 8.8 9.1 3.7 8.0 1.2 3.6 3 0 0 3 3 3 0 Latarcin precursor DUF945 PF06097.11 KXX83029.1 - 3.8 6.5 6.0 2.4 7.2 4.0 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF945) Med3 PF11593.8 KXX83029.1 - 5.4 6.1 8.0 13 4.8 8.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NTP_transferase PF00483.23 KXX83030.1 - 3.8e-31 108.6 0.0 4.7e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KXX83030.1 - 4.7e-07 29.3 4.9 6.2e-06 25.7 0.0 3.5 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXX83030.1 - 1.1e-06 29.1 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KXX83030.1 - 0.029 14.1 0.0 0.085 12.6 0.0 1.7 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase F-box PF00646.33 KXX83032.1 - 2.4e-11 43.2 3.4 4.9e-11 42.2 3.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXX83032.1 - 1.4e-08 34.5 2.2 3.6e-08 33.2 2.2 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KXX83032.1 - 6e-05 22.9 0.3 0.00011 22.0 0.3 1.4 1 0 0 1 1 1 1 F-box PRANC PF09372.10 KXX83032.1 - 0.085 13.2 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 PRANC domain zf-C2H2_jaz PF12171.8 KXX83033.1 - 0.00032 20.9 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Med7 PF05983.11 KXX83034.1 - 2.1e-55 187.8 0.3 2.4e-55 187.6 0.3 1.1 1 0 0 1 1 1 1 MED7 protein TBCC_N PF16752.5 KXX83034.1 - 0.016 15.6 0.4 0.044 14.2 0.3 1.7 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain RICTOR_M PF14666.6 KXX83034.1 - 0.019 14.7 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Proteasome PF00227.26 KXX83035.1 - 1.2e-60 204.2 0.1 1.5e-60 203.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXX83035.1 - 1.3e-13 50.4 0.2 4.5e-13 48.6 0.2 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KXX83035.1 - 0.014 15.5 0.4 0.04 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KXX83035.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.21 KXX83036.1 - 4.5e-28 97.7 1.8 4.5e-28 97.7 1.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF2975 PF11188.8 KXX83036.1 - 0.01 15.7 3.2 0.022 14.6 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) AveC_like PF17198.4 KXX83036.1 - 0.13 11.7 1.0 0.24 10.8 0.8 1.6 2 0 0 2 2 2 0 Spirocyclase AveC-like WD40 PF00400.32 KXX83037.1 - 5.3e-41 137.8 19.4 1.9e-05 25.3 0.5 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KXX83037.1 - 5.8e-12 45.3 0.4 1.1e-11 44.4 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX83037.1 - 5.8e-11 42.0 1.1 1.8e-10 40.4 0.7 2.1 2 1 1 3 3 3 1 F-box domain ANAPC4_WD40 PF12894.7 KXX83037.1 - 1e-06 28.9 1.8 2.4 8.5 0.0 5.7 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KXX83037.1 - 0.0007 19.5 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 F-box PQQ_2 PF13360.6 KXX83037.1 - 0.0029 17.2 1.4 0.14 11.7 0.5 2.7 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.8 KXX83037.1 - 0.0041 15.8 6.6 5.7 5.4 0.1 4.7 2 1 3 5 5 5 3 Nucleoporin Nup120/160 CDtoxinA PF03498.14 KXX83037.1 - 0.27 10.8 2.1 8.5 5.9 0.0 2.7 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain zf-met PF12874.7 KXX83038.1 - 0.022 15.2 2.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KXX83038.1 - 0.049 14.1 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KXX83038.1 - 0.14 12.4 0.9 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Dehydrin PF00257.19 KXX83038.1 - 0.8 10.2 8.6 0.041 14.4 1.7 2.1 2 0 0 2 2 2 0 Dehydrin zf-BED PF02892.15 KXX83038.1 - 1.7 8.7 5.6 1 9.5 3.0 1.9 2 0 0 2 2 2 0 BED zinc finger Cutinase PF01083.22 KXX83040.1 - 2.8e-48 164.2 0.0 3.3e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KXX83040.1 - 0.00036 20.5 0.0 0.00046 20.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KXX83040.1 - 0.028 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.16 KXX83040.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KXX83041.1 - 9.5e-14 51.6 0.2 1.3e-13 51.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXX83041.1 - 6.6e-13 49.8 6.5 8e-13 49.5 6.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXX83041.1 - 8.1e-09 35.1 0.0 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXX83041.1 - 6.3e-05 22.7 0.0 0.0001 22.1 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KXX83041.1 - 0.00087 19.5 0.1 0.0012 19.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 KXX83041.1 - 0.051 13.4 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DLH PF01738.18 KXX83041.1 - 0.21 11.1 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family zf-U1 PF06220.12 KXX83043.1 - 3.3e-07 30.0 0.4 5.2e-07 29.3 0.4 1.3 1 0 0 1 1 1 1 U1 zinc finger DUF4140 PF13600.6 KXX83043.1 - 3.5 8.1 10.4 4.7 7.7 0.5 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) PIR PF00399.19 KXX83045.1 - 0.00051 19.5 14.0 0.0043 16.6 1.4 3.1 2 0 0 2 2 2 2 Yeast PIR protein repeat RIO1 PF01163.22 KXX83046.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KXX83046.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain HET PF06985.11 KXX83047.1 - 1.1e-16 61.4 0.0 1.6e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_L6e PF01159.19 KXX83048.1 - 8e-40 135.8 0.2 1.3e-39 135.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e V-SNARE_C PF12352.8 KXX83049.1 - 9.9e-12 45.0 0.2 9.9e-12 45.0 0.2 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus STAT_alpha PF01017.20 KXX83049.1 - 0.0011 18.9 0.5 0.015 15.2 0.6 2.2 2 1 0 2 2 2 1 STAT protein, all-alpha domain Atg14 PF10186.9 KXX83049.1 - 0.014 14.5 4.9 0.017 14.3 4.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SATase_N PF06426.14 KXX83049.1 - 0.03 14.7 3.4 0.074 13.4 0.7 2.3 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal Spc7 PF08317.11 KXX83049.1 - 0.37 9.6 6.3 0.066 12.1 3.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein CorA PF01544.18 KXX83049.1 - 3.4 6.9 10.6 0.59 9.4 6.3 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein APG6_N PF17675.1 KXX83049.1 - 4.4 7.8 13.0 12 6.5 11.2 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region STT3 PF02516.14 KXX83050.1 - 1.5e-144 482.5 32.7 8e-140 467.0 30.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Ribosomal_L29 PF00831.23 KXX83051.1 - 9e-17 60.8 1.6 9e-17 60.8 1.6 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein RhoGAP PF00620.27 KXX83052.1 - 3.4e-37 127.6 0.0 8.7e-37 126.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KXX83052.1 - 3e-29 101.0 36.8 1.3e-11 44.6 5.6 5.2 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.12 KXX83052.1 - 0.15 11.8 0.5 1 9.0 0.1 2.7 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-ribbon_3 PF13248.6 KXX83052.1 - 0.44 10.0 4.5 4.2 6.9 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KXX83052.1 - 7.4 6.6 11.5 56 3.8 0.2 4.7 4 1 1 5 5 5 0 Nudix N-terminal 3Beta_HSD PF01073.19 KXX83053.1 - 6e-62 209.2 0.0 7e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXX83053.1 - 5.9e-34 117.6 0.4 8.4e-34 117.1 0.4 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXX83053.1 - 8.2e-22 78.0 0.0 4.3e-17 62.5 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXX83053.1 - 6.8e-14 51.6 0.5 7.9e-11 41.6 0.2 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXX83053.1 - 9.7e-13 47.9 0.2 1.2e-12 47.5 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXX83053.1 - 6.5e-11 42.5 0.1 9.7e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXX83053.1 - 1.3e-07 31.0 0.6 1.5e-06 27.5 0.5 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KXX83053.1 - 0.00038 20.1 0.1 0.00066 19.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KXX83053.1 - 0.00091 19.5 0.1 0.0019 18.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KXX83053.1 - 0.0014 18.9 0.2 0.0032 17.7 0.2 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KXX83053.1 - 0.003 18.2 0.0 0.0062 17.2 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain KR PF08659.10 KXX83053.1 - 0.0054 16.7 2.9 0.035 14.0 2.9 2.1 1 1 0 1 1 1 1 KR domain Sec63 PF02889.16 KXX83054.1 - 1.2e-165 548.9 0.0 4.5e-93 311.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXX83054.1 - 1.3e-49 168.4 0.1 4e-28 98.3 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KXX83054.1 - 5.8e-34 116.6 0.7 1.5e-33 115.3 0.7 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KXX83054.1 - 7.6e-25 87.9 0.0 5.7e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXX83054.1 - 1.3e-11 44.8 0.0 3.4e-07 30.6 0.0 3.9 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXX83054.1 - 3.4e-08 33.8 0.1 0.0034 17.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 KXX83054.1 - 9.7e-05 21.6 0.0 0.15 11.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 KXX83054.1 - 0.0079 15.7 0.0 0.5 9.8 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 KXX83054.1 - 0.0081 16.0 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXX83054.1 - 0.0098 16.2 0.0 7.5 6.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KXX83054.1 - 0.011 15.3 0.0 2 7.8 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 KXX83054.1 - 0.019 14.5 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region TFIIE_alpha PF02002.17 KXX83054.1 - 1.3 8.9 4.2 22 5.0 0.0 3.6 4 0 0 4 4 4 0 TFIIE alpha subunit PWWP PF00855.17 KXX83056.1 - 3.3e-14 53.0 0.0 3.3e-14 53.0 0.0 3.1 3 2 1 4 4 4 1 PWWP domain Med26 PF08711.11 KXX83056.1 - 0.0012 18.8 0.1 0.0035 17.3 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain ORC3_N PF07034.11 KXX83057.1 - 3.6e-37 128.2 0.3 8.2e-37 127.0 0.3 1.6 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KXX83057.1 - 3.5e-25 88.7 3.4 6.4e-14 52.2 0.0 3.4 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal BPL_N PF09825.9 KXX83057.1 - 0.15 11.1 0.1 0.27 10.3 0.1 1.4 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF2417 PF10329.9 KXX83058.1 - 1.9e-86 289.3 3.2 2.4e-86 289.0 3.2 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2975 PF11188.8 KXX83058.1 - 0.013 15.3 3.2 0.013 15.3 3.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) ABC2_membrane_3 PF12698.7 KXX83058.1 - 0.14 11.2 9.7 0.24 10.4 9.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4632 PF15451.6 KXX83059.1 - 0.45 10.6 4.0 29 4.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) UQ_con PF00179.26 KXX83060.1 - 2e-39 134.5 0.0 4.5e-28 97.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX83060.1 - 0.0022 17.7 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.22 KXX83060.1 - 0.033 14.5 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 RWD domain Rep_fac_C PF08542.11 KXX83061.1 - 4e-22 78.4 0.0 7.4e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXX83061.1 - 2e-16 60.6 0.0 6.9e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXX83061.1 - 8.2e-13 48.4 0.0 1.3e-10 41.3 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 KXX83061.1 - 1e-05 25.4 0.0 2.9e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXX83061.1 - 2.9e-05 24.5 0.0 0.001 19.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX83061.1 - 3.1e-05 24.3 0.0 0.0017 18.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXX83061.1 - 4.8e-05 23.3 0.1 0.00014 21.8 0.0 1.6 1 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXX83061.1 - 0.00025 21.0 0.0 0.00097 19.1 0.0 2.0 3 0 0 3 3 3 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KXX83061.1 - 0.00026 20.4 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 KXX83061.1 - 0.0012 19.2 0.0 0.0039 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 KXX83061.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXX83061.1 - 0.0031 17.8 0.0 0.018 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXX83061.1 - 0.005 16.4 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KXX83061.1 - 0.0054 16.7 0.1 0.03 14.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXX83061.1 - 0.0069 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXX83061.1 - 0.007 16.1 0.0 0.024 14.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KXX83061.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_28 PF13521.6 KXX83061.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXX83061.1 - 0.018 14.8 0.0 0.068 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXX83061.1 - 0.033 13.4 0.0 0.088 12.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KXX83061.1 - 0.043 13.8 0.0 0.18 11.8 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KXX83061.1 - 0.048 14.2 0.0 0.13 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KXX83061.1 - 0.095 12.6 0.0 0.48 10.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KXX83061.1 - 0.11 11.8 0.1 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KXX83061.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase LAMTOR PF15454.6 KXX83062.1 - 2.2e-11 44.2 0.4 5.3e-11 43.0 0.3 1.7 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Com_YlbF PF06133.11 KXX83062.1 - 0.014 15.9 0.5 0.025 15.2 0.5 1.4 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF713 PF05218.14 KXX83062.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) FlaC_arch PF05377.11 KXX83062.1 - 0.16 12.4 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Tagatose_6_P_K PF08013.11 KXX83063.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Beta-lactamase PF00144.24 KXX83065.1 - 5.9e-28 98.1 0.3 9.9e-27 94.0 0.3 2.0 1 1 0 1 1 1 1 Beta-lactamase PAN_4 PF14295.6 KXX83066.1 - 1.7e-06 27.9 0.2 3.1e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 PAN domain MANEC PF07502.14 KXX83066.1 - 0.043 14.1 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 MANEC domain PAN_1 PF00024.26 KXX83066.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 PAN domain Nuc_deoxyri_tr2 PF15891.5 KXX83067.1 - 6e-36 123.0 0.0 6e-35 119.8 0.0 2.0 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase like Sushi PF00084.20 KXX83067.1 - 0.024 15.3 0.1 0.05 14.2 0.1 1.5 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) DUF434 PF04256.12 KXX83067.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF434) DUF3716 PF12511.8 KXX83069.1 - 4.6e-15 55.4 4.8 4.6e-15 55.4 4.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) Gpi16 PF04113.14 KXX83070.1 - 3.8e-244 811.3 0.0 4.7e-244 811.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KXX83071.1 - 1.7e-67 227.7 0.1 2.1e-67 227.4 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 KXX83071.1 - 0.0087 15.2 0.4 0.012 14.7 0.4 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Occludin_ELL PF07303.13 KXX83071.1 - 0.012 16.3 0.4 0.069 13.9 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain Bcr-Abl_Oligo PF09036.10 KXX83071.1 - 0.059 13.4 0.3 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DHR10 PF18595.1 KXX83071.1 - 0.14 12.2 1.6 0.49 10.5 0.1 2.2 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain FAD_binding_3 PF01494.19 KXX83073.1 - 1.4e-06 27.8 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Peptidase_M43 PF05572.13 KXX83076.1 - 2e-12 47.3 0.2 4e-12 46.3 0.1 1.7 2 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Peptidase_M7 PF02031.16 KXX83076.1 - 0.00017 21.7 0.7 0.00034 20.7 0.7 1.5 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_5 PF13688.6 KXX83076.1 - 0.00036 20.7 1.1 0.0008 19.6 1.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXX83076.1 - 0.0024 17.6 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KXX83076.1 - 0.0062 17.0 0.0 0.014 15.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KXX83076.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 KXX83076.1 - 0.013 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 KXX83076.1 - 0.097 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KXX83076.1 - 0.25 10.9 0.4 0.44 10.1 0.4 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Metallopep PF12044.8 KXX83076.1 - 0.25 9.9 2.0 0.36 9.4 2.0 1.1 1 0 0 1 1 1 0 Putative peptidase family adh_short_C2 PF13561.6 KXX83077.1 - 7.1e-57 192.7 0.3 8.7e-57 192.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX83077.1 - 1.5e-42 145.3 0.3 2e-42 144.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase RNase_T PF00929.24 KXX83078.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.1 1 0 0 1 1 1 0 Exonuclease MARVEL PF01284.23 KXX83079.1 - 6.7e-06 26.2 17.8 2.7e-05 24.2 17.7 1.8 1 1 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 KXX83079.1 - 0.013 15.3 4.6 0.013 15.3 4.6 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF588) Peptidase_M56 PF05569.11 KXX83079.1 - 0.023 13.9 1.5 0.031 13.5 0.4 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 TctB PF07331.11 KXX83079.1 - 9.4 6.5 10.8 24 5.2 8.1 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Pkinase_fungal PF17667.1 KXX83081.1 - 4.6e-125 417.6 0.0 5.6e-125 417.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KXX83081.1 - 7.1e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXX83081.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MauJ PF17419.2 KXX83081.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Methylamine utilization protein MauJ POTRA_TamA_1 PF17243.2 KXX83081.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 POTRA domain TamA domain 1 SPOC PF07744.13 KXX83082.1 - 2.2e-26 92.6 0.0 4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KXX83082.1 - 6.5e-21 74.9 0.3 1.6e-20 73.7 0.3 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KXX83082.1 - 8.9e-10 38.3 7.8 1.7e-09 37.4 7.8 1.5 1 0 0 1 1 1 1 PHD-finger SUIM_assoc PF16619.5 KXX83082.1 - 0.029 14.4 0.8 0.029 14.4 0.8 4.4 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 zf-CW PF07496.15 KXX83082.1 - 0.75 9.9 3.2 1.7 8.8 3.2 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger 2-oxoacid_dh PF00198.23 KXX83083.1 - 7.9e-73 244.7 0.0 1.1e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXX83083.1 - 6.8e-18 64.3 0.2 1.4e-17 63.3 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXX83083.1 - 1.6e-13 50.7 0.2 4.5e-13 49.3 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain ATP-synt_10 PF05176.14 KXX83084.1 - 7.2e-79 264.6 0.0 9e-79 264.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein RTC PF01137.21 KXX83085.1 - 3.8e-28 98.2 2.4 9.5e-28 96.9 1.9 1.6 1 1 1 2 2 2 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KXX83085.1 - 1.1e-21 77.2 0.7 2.2e-21 76.3 0.3 1.7 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1746 PF08508.10 KXX83086.1 - 2.1e-39 134.4 2.3 3.5e-39 133.7 2.3 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CPSase_L_D2 PF02786.17 KXX83087.1 - 9.1e-111 368.4 0.1 4.4e-84 281.2 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KXX83087.1 - 6.5e-40 136.3 0.0 2.3e-39 134.5 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KXX83087.1 - 5.4e-22 78.2 0.1 1.7e-10 40.8 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXX83087.1 - 1.7e-19 70.2 1.0 1.2e-09 38.0 0.3 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KXX83087.1 - 4.2e-11 42.7 0.0 0.00031 20.5 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KXX83087.1 - 3.7e-06 26.8 0.4 0.034 13.9 0.2 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KXX83087.1 - 1.2e-05 25.5 0.2 0.05 13.6 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KXX83087.1 - 1.5e-05 24.6 0.1 0.061 12.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 KXX83087.1 - 0.00015 21.4 0.1 0.032 13.8 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KXX83087.1 - 0.00028 20.5 0.1 0.0032 17.1 0.1 2.5 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.21 KXX83087.1 - 0.017 14.6 0.1 0.15 11.5 0.0 2.6 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family NPL4 PF05021.15 KXX83088.1 - 1.3e-140 468.1 0.0 2.6e-140 467.1 0.0 1.4 2 0 0 2 2 2 1 NPL4 family zf-NPL4 PF05020.15 KXX83088.1 - 3.1e-70 234.9 0.2 5.9e-70 234.0 0.2 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KXX83088.1 - 3.6e-05 24.1 0.0 0.00014 22.3 0.0 2.0 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 Metallophos PF00149.28 KXX83089.1 - 1e-08 35.9 0.0 2.2e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX83089.1 - 4.7e-08 33.4 0.1 4.9e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DUF4187 PF13821.6 KXX83091.1 - 8.5e-22 76.7 1.3 8.5e-22 76.7 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KXX83091.1 - 0.036 13.9 1.5 0.091 12.7 1.5 1.7 1 0 0 1 1 1 0 G-patch domain PPR_2 PF13041.6 KXX83092.1 - 4.6e-09 36.3 3.5 9.1e-07 29.0 0.0 4.2 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.20 KXX83092.1 - 0.0024 18.0 8.0 0.0063 16.7 0.0 5.1 7 0 0 7 7 7 1 PPR repeat PPR_long PF17177.4 KXX83092.1 - 0.01 15.2 0.1 0.18 11.1 0.0 2.8 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 KXX83092.1 - 0.046 13.6 0.0 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase expression UPF0184 PF03670.13 KXX83092.1 - 0.064 13.6 0.4 1 9.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) BTAD PF03704.17 KXX83092.1 - 0.16 12.4 2.3 51 4.3 0.1 3.8 3 0 0 3 3 3 0 Bacterial transcriptional activator domain YAcAr PF10686.9 KXX83092.1 - 0.93 9.5 2.8 1.7 8.7 0.0 3.0 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family Sec66 PF09802.9 KXX83093.1 - 5.6e-81 270.4 0.2 6.7e-81 270.2 0.2 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 rRNA_processing PF08524.11 KXX83093.1 - 0.011 15.8 0.8 0.018 15.0 0.8 1.4 1 0 0 1 1 1 0 rRNA processing DUF3848 PF12959.7 KXX83093.1 - 0.063 13.4 0.4 0.22 11.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3848) CDPS PF16715.5 KXX83093.1 - 0.12 12.0 1.3 0.16 11.6 1.3 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase Blt1 PF12754.7 KXX83094.1 - 0.43 10.9 1.8 0.67 10.3 1.8 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain DEAD PF00270.29 KXX83096.1 - 9.7e-52 175.3 0.0 1.6e-49 168.1 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXX83096.1 - 1.6e-27 96.0 0.0 4.7e-27 94.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXX83096.1 - 0.0015 18.5 0.0 0.0043 17.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RAP1 PF07218.11 KXX83096.1 - 1.6 6.9 3.2 2.6 6.2 3.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LRR_6 PF13516.6 KXX83097.1 - 0.00011 22.0 18.0 13 6.1 0.1 8.8 9 0 0 9 9 9 4 Leucine Rich repeat Ribosomal_L5e PF17144.4 KXX83098.1 - 1.4e-79 265.8 0.1 2.1e-79 265.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KXX83098.1 - 4.9e-35 120.4 8.3 4.9e-35 120.4 8.3 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KXX83098.1 - 0.039 14.3 0.1 0.09 13.2 0.1 1.6 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Med1 PF10744.9 KXX83099.1 - 6e-107 358.3 0.0 7.9e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 SpoIIP PF07454.11 KXX83100.1 - 0.0062 16.0 3.7 0.011 15.3 3.7 1.4 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 KXX83100.1 - 0.0085 15.7 33.0 0.017 14.7 33.0 1.4 1 0 0 1 1 1 1 Spt20 family Endostatin PF06482.11 KXX83100.1 - 0.015 14.8 10.0 0.031 13.7 10.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SHE3 PF17078.5 KXX83100.1 - 0.03 14.0 0.6 0.03 14.0 0.6 2.3 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 DUF4763 PF15960.5 KXX83100.1 - 0.061 12.6 0.1 0.061 12.6 0.1 2.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4763) Pex14_N PF04695.13 KXX83100.1 - 0.16 12.6 29.8 0.043 14.5 26.4 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 KXX83100.1 - 0.2 11.7 3.8 0.45 10.5 3.8 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KXX83100.1 - 0.35 9.6 11.1 0.018 13.8 5.9 1.5 2 0 0 2 2 2 0 Presenilin DUF4770 PF15994.5 KXX83100.1 - 0.76 10.0 11.7 1.6 9.0 11.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Band_3_cyto PF07565.13 KXX83100.1 - 1.2 8.9 6.9 0.25 11.1 3.2 1.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EIIBC-GUT_N PF03612.14 KXX83100.1 - 1.6 8.4 6.5 3.6 7.3 6.5 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3464 PF11947.8 KXX83100.1 - 1.7 8.4 10.2 4.3 7.1 10.2 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Tim54 PF11711.8 KXX83100.1 - 2.1 7.1 13.4 0.077 11.8 7.4 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM76 PF16046.5 KXX83100.1 - 7.1 5.9 13.0 35 3.6 13.0 1.9 1 1 0 1 1 1 0 FAM76 protein Pex19 PF04614.12 KXX83101.1 - 3.3e-77 259.6 15.1 4.9e-77 259.0 15.1 1.3 1 0 0 1 1 1 1 Pex19 protein family PP2C_C PF07830.13 KXX83101.1 - 0.00098 19.5 3.5 1.8 9.1 0.1 3.6 2 1 1 3 3 3 2 Protein serine/threonine phosphatase 2C, C-terminal domain Pkinase PF00069.25 KXX83102.1 - 1.8e-43 148.8 0.0 8.3e-41 140.1 0.0 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXX83102.1 - 8.2e-22 77.7 0.0 1.8e-21 76.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 KXX83103.1 - 7.4e-34 116.2 0.0 2.6e-13 50.4 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) SesA PF17107.5 KXX83103.1 - 7.5e-32 110.1 0.1 2.4e-31 108.5 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_5 PF13857.6 KXX83103.1 - 3.5e-21 75.0 0.0 2e-08 34.3 0.0 5.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX83103.1 - 2.4e-20 72.6 0.0 9.2e-07 29.3 0.0 5.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX83103.1 - 6.6e-19 66.0 0.1 0.032 14.8 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KXX83103.1 - 3.1e-17 62.1 0.0 0.0024 18.2 0.0 7.2 6 1 0 6 6 6 3 Ankyrin repeat NACHT PF05729.12 KXX83103.1 - 2e-09 37.6 0.1 2.7e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KXX83103.1 - 2.2e-07 31.4 0.3 9.4e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXX83103.1 - 0.0012 19.1 0.3 0.018 15.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KXX83103.1 - 0.002 18.5 0.0 0.016 15.6 0.0 2.5 3 0 0 3 3 3 1 RNA helicase FAM196 PF15265.6 KXX83103.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 FAM196 family AAA_14 PF13173.6 KXX83103.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Formyl_trans_N PF00551.19 KXX83105.1 - 2.7e-23 82.7 0.0 3.7e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase WD40 PF00400.32 KXX83106.1 - 2.5e-47 157.9 11.8 2.3e-07 31.4 0.0 8.4 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX83106.1 - 1.6e-10 41.1 0.1 0.0013 19.0 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX83106.1 - 1e-06 27.7 0.0 0.0018 17.0 0.0 3.8 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXX83106.1 - 0.014 14.2 0.0 0.38 9.4 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like bZIP_2 PF07716.15 KXX83106.1 - 0.065 13.3 0.5 0.13 12.4 0.5 1.4 1 0 0 1 1 1 0 Basic region leucine zipper PRD1_DD PF11087.8 KXX83106.1 - 0.31 10.8 1.6 0.58 9.9 0.1 2.0 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery Pescadillo_N PF06732.11 KXX83107.1 - 4.5e-123 410.1 0.1 4.5e-123 410.1 0.1 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus Astro_capsid_p PF12226.8 KXX83107.1 - 6.7e-07 28.8 14.5 6.7e-07 28.8 14.5 1.5 2 0 0 2 2 2 1 Turkey astrovirus capsid protein BRCT_2 PF16589.5 KXX83107.1 - 0.02 15.3 0.2 0.12 12.8 0.2 2.2 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Nop53 PF07767.11 KXX83107.1 - 0.037 13.4 29.1 0.08 12.3 29.1 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Ribosomal_L14e PF01929.17 KXX83107.1 - 0.094 13.2 6.1 0.24 11.9 6.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L14 PIG-U PF06728.13 KXX83108.1 - 5.5e-123 410.8 25.2 6.3e-123 410.6 25.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 KXX83108.1 - 0.92 9.2 10.6 2.8 7.6 10.2 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain BatA PF07584.11 KXX83108.1 - 6.1 7.3 9.3 0.24 11.8 0.4 3.2 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Pyridoxal_deC PF00282.19 KXX83110.1 - 5.6e-14 51.6 0.1 8.9e-11 41.1 0.0 3.0 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain DHquinase_I PF01487.15 KXX83111.1 - 3.1e-46 158.5 0.0 4.4e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase GidB PF02527.15 KXX83111.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF2228 PF10228.9 KXX83111.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) PhoD PF09423.10 KXX83112.1 - 0.00051 19.2 0.1 0.0044 16.1 0.1 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase HNH_2 PF13391.6 KXX83113.1 - 8.9e-06 25.7 0.2 3.2e-05 24.0 0.2 2.0 1 1 0 1 1 1 1 HNH endonuclease CxxCxxCC PF03692.15 KXX83113.1 - 0.13 12.9 1.2 0.19 12.5 0.2 1.8 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain UPF0183 PF03676.14 KXX83114.1 - 1.4e-49 169.4 0.0 4.3e-26 92.1 0.0 3.9 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) HAD_2 PF13419.6 KXX83115.1 - 1.8e-05 24.9 0.0 2.7e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX83115.1 - 0.012 15.9 0.0 0.68 10.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ATG2_CAD PF13329.6 KXX83116.1 - 4.8e-51 172.6 0.0 1.4e-50 171.0 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KXX83116.1 - 1.2e-31 108.9 3.6 5.8e-31 106.7 0.4 3.4 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 KXX83116.1 - 6.1e-07 29.6 0.1 3.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KXX83116.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal zf-UBR PF02207.20 KXX83117.1 - 5.9e-14 52.0 4.9 5.9e-14 52.0 4.9 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Acyl-CoA_dh_1 PF00441.24 KXX83118.1 - 8e-35 120.3 1.0 1.2e-34 119.7 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXX83118.1 - 3.8e-20 71.8 0.1 1e-19 70.5 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXX83118.1 - 1.7e-15 57.0 0.1 3.1e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXX83118.1 - 1.5e-05 25.6 0.1 9.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXX83118.1 - 5.6e-05 23.4 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Amino_oxidase PF01593.24 KXX83119.1 - 9e-55 186.7 0.0 1.2e-54 186.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXX83119.1 - 2.9e-16 59.4 0.0 6.3e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXX83119.1 - 3e-09 37.0 0.1 3.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXX83119.1 - 7.6e-09 35.2 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX83119.1 - 2.1e-05 24.3 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXX83119.1 - 3.8e-05 22.6 0.1 0.0018 17.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXX83119.1 - 0.00015 22.2 0.1 0.00038 21.0 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX83119.1 - 0.0011 18.1 0.1 0.0028 16.8 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXX83119.1 - 0.0018 17.6 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXX83119.1 - 0.0048 16.2 0.1 0.0073 15.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXX83119.1 - 0.013 14.9 0.1 0.023 14.1 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXX83119.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KXX83119.1 - 0.038 13.2 0.5 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXX83119.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXX83119.1 - 0.19 10.7 0.2 1 8.3 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Prenylcys_lyase PF07156.14 KXX83119.1 - 0.22 10.6 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase GIDA PF01134.22 KXX83119.1 - 0.24 10.4 0.1 0.65 9.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Tom37 PF10568.9 KXX83120.1 - 1e-32 113.1 1.2 1.6e-32 112.5 1.2 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KXX83120.1 - 0.014 16.1 0.0 0.03 15.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXX83120.1 - 0.14 11.9 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.22 KXX83121.1 - 3e-145 484.8 0.0 4.1e-145 484.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXX83121.1 - 6e-20 71.3 0.0 3.3e-12 45.9 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXX83121.1 - 2.8e-19 69.6 0.0 5.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXX83121.1 - 0.011 15.1 0.0 0.52 9.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KXX83121.1 - 0.032 14.1 6.0 0.1 12.5 6.0 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Helicase_C PF00271.31 KXX83122.1 - 1.4e-24 86.6 0.0 3.5e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXX83122.1 - 1.4e-24 86.8 0.0 1.1e-14 54.7 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KXX83122.1 - 6e-05 23.1 0.1 0.00027 21.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MecA PF05389.12 KXX83122.1 - 0.0054 16.4 1.1 0.01 15.5 1.1 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) SbcCD_C PF13558.6 KXX83122.1 - 7.1 6.9 0.0 7.1 6.9 0.0 3.4 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit SPRY PF00622.28 KXX83123.1 - 0.00062 19.9 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Na_Ca_ex PF01699.24 KXX83124.1 - 8.2e-22 77.8 22.0 8.1e-18 64.8 15.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.12 KXX83124.1 - 0.51 10.5 0.0 0.51 10.5 0.0 3.1 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) HABP4_PAI-RBP1 PF04774.15 KXX83126.1 - 0.021 15.7 2.5 0.038 14.8 2.5 1.5 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family CIAPIN1 PF05093.13 KXX83127.1 - 4.1e-42 142.8 4.3 6.4e-42 142.1 4.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KXX83127.1 - 2.6e-37 128.0 0.0 3.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus RNA_Me_trans PF04252.13 KXX83128.1 - 6.1e-83 277.3 0.0 6.9e-83 277.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DHO_dh PF01180.21 KXX83129.1 - 7.6e-18 64.7 0.0 1.3e-17 63.9 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 KXX83129.1 - 0.093 11.7 0.3 0.13 11.2 0.3 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Abhydrolase_2 PF02230.16 KXX83130.1 - 2.4e-25 89.6 0.0 3e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXX83130.1 - 1.2e-05 26.1 0.9 1.6e-05 25.7 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KXX83130.1 - 0.00025 21.0 0.2 0.00038 20.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXX83130.1 - 0.0031 17.0 0.1 1.8 8.0 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXX83130.1 - 0.04 13.2 0.6 1.6 7.9 0.2 2.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 APH PF01636.23 KXX83131.1 - 5.8e-09 36.2 1.5 4e-08 33.5 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXX83131.1 - 0.0075 15.9 0.0 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KXX83131.1 - 0.065 12.5 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Syja_N PF02383.18 KXX83132.1 - 3.1e-92 309.3 0.0 3.9e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.22 KXX83133.1 - 1.5e-58 197.0 0.2 1.7e-58 196.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXX83133.1 - 3.2e-36 124.2 0.2 6.5e-36 123.2 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX83133.1 - 2.5e-15 56.4 0.1 3e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXX83133.1 - 6e-07 29.0 0.0 7.5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXX83133.1 - 1.3e-06 28.1 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX83133.1 - 2.7e-06 27.4 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX83133.1 - 1.6e-05 24.9 1.0 0.091 12.7 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KXX83133.1 - 0.038 14.4 0.2 0.076 13.4 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KXX83133.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KXX83133.1 - 0.1 12.8 0.0 4.9 7.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain Methyltransf_34 PF11312.8 KXX83134.1 - 7.5e-111 370.2 0.0 8.9e-111 370.0 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Transketolase_N PF00456.21 KXX83135.1 - 6.2e-157 521.8 0.0 8.4e-157 521.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXX83135.1 - 2.2e-45 154.5 0.0 3.6e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXX83135.1 - 2.3e-14 53.3 0.0 4.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KXX83135.1 - 0.00026 20.3 0.0 0.00099 18.4 0.0 1.8 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KXX83135.1 - 0.0004 20.2 0.7 0.0041 16.9 0.1 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 KXX83135.1 - 0.088 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal zf-RING_13 PF17977.1 KXX83135.1 - 0.15 12.2 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CEP63 PF17045.5 KXX83136.1 - 0.00016 21.7 6.0 0.00016 21.7 6.0 4.2 3 1 1 5 5 5 1 Centrosomal protein of 63 kDa Filament PF00038.21 KXX83136.1 - 0.00025 20.7 11.5 0.00025 20.7 11.5 5.3 3 1 2 5 5 5 1 Intermediate filament protein DUF4407 PF14362.6 KXX83136.1 - 0.00049 19.6 4.3 0.00049 19.6 4.3 3.8 2 1 1 3 3 2 1 Domain of unknown function (DUF4407) THOC7 PF05615.13 KXX83136.1 - 0.011 16.0 4.0 0.011 16.0 4.0 5.5 4 1 1 6 6 6 0 Tho complex subunit 7 TcdB_N PF12918.7 KXX83136.1 - 0.014 15.7 0.8 0.23 11.8 0.1 2.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain COG5 PF10392.9 KXX83136.1 - 0.04 14.1 1.2 0.04 14.1 1.2 2.9 1 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 KXX83136.1 - 0.11 12.6 11.1 0.62 10.1 5.1 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 KXX83136.1 - 0.12 12.5 0.2 0.12 12.5 0.2 7.2 7 1 2 9 9 9 0 bZIP transcription factor Baculo_PEP_C PF04513.12 KXX83136.1 - 0.18 11.8 4.5 8.5 6.4 0.3 3.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 KXX83136.1 - 0.21 9.7 20.1 0.075 11.2 7.3 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Bacillus_HBL PF05791.11 KXX83136.1 - 1.2 8.9 5.4 2.5 7.9 0.8 2.9 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Med13_C PF06333.12 KXX83136.1 - 2 7.6 10.2 3.2 6.9 10.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain APC_N_CC PF16689.5 KXX83136.1 - 8 6.6 18.9 0.44 10.6 0.5 5.1 5 0 0 5 5 5 0 Coiled-coil N-terminus of APC, dimerisation domain FSA_C PF10479.9 KXX83136.1 - 9 4.3 6.3 15 3.5 6.3 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CM_1 PF07736.11 KXX83137.1 - 0.068 13.6 0.3 0.13 12.6 0.3 1.5 1 0 0 1 1 1 0 Chorismate mutase type I 4HB PF17947.1 KXX83137.1 - 0.15 12.2 0.2 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Four helical bundle domain Saf_2TM PF18303.1 KXX83138.1 - 0.082 12.5 0.9 0.68 9.5 0.0 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain ATP-synt_C PF00137.21 KXX83139.1 - 2.5e-34 117.4 35.7 1.2e-21 76.8 16.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 KXX83140.1 - 1.2e-25 89.0 0.1 1.5e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXX83140.1 - 0.00057 20.0 0.2 0.0029 17.7 0.2 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KXX83140.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Syja_N PF02383.18 KXX83141.1 - 2.6e-93 312.8 0.0 3.8e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KXX83141.1 - 6.1e-42 142.0 0.0 1.2e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase FSH1 PF03959.13 KXX83142.1 - 0.097 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KXX83142.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXX83142.1 - 0.18 11.4 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXX83143.1 - 2.6e-07 30.7 0.0 4.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase MCM PF00493.23 KXX83144.1 - 1.6e-100 334.9 1.4 2.8e-100 334.1 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KXX83144.1 - 2.9e-39 133.8 0.2 5.3e-39 132.9 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KXX83144.1 - 1e-33 116.8 32.7 1e-33 116.8 32.7 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KXX83144.1 - 9.3e-26 90.1 0.5 2.4e-25 88.8 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXX83144.1 - 4e-15 56.3 0.1 9.3e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXX83144.1 - 1e-07 31.6 0.0 6.1e-06 25.8 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXX83144.1 - 2.1e-06 27.8 0.0 4.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXX83144.1 - 0.0016 18.3 0.0 0.015 15.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXX83144.1 - 0.0025 17.5 0.2 0.017 14.8 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KXX83144.1 - 0.21 12.3 0.5 0.58 10.9 0.5 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 KXX83144.1 - 0.45 9.9 1.9 0.91 8.9 1.9 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger HAD_2 PF13419.6 KXX83145.1 - 0.00023 21.3 0.0 0.00049 20.2 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXX83145.1 - 0.047 14.0 0.0 0.14 12.4 0.0 1.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase CHAT PF12770.7 KXX83146.1 - 4e-32 111.8 0.0 1e-31 110.4 0.0 1.6 1 1 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 KXX83147.1 - 0.0042 17.2 4.6 5.4 7.5 0.1 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXX83147.1 - 0.0085 15.9 0.1 0.0085 15.9 0.1 8.0 7 2 1 8 8 8 2 Tetratricopeptide repeat TFR_dimer PF04253.15 KXX83147.1 - 0.0089 16.1 0.3 0.041 14.0 0.1 2.3 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain TPR_1 PF00515.28 KXX83147.1 - 0.026 14.3 3.7 30 4.6 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXX83147.1 - 0.1 12.8 8.3 31 5.0 0.2 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TAP42 PF04177.12 KXX83147.1 - 0.11 11.6 0.2 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 TAP42-like family TPR_17 PF13431.6 KXX83147.1 - 0.14 12.6 0.1 5.7 7.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HisKA_3 PF07730.13 KXX83147.1 - 0.64 10.6 5.6 35 5.0 0.0 4.8 5 1 0 5 5 5 0 Histidine kinase TPR_19 PF14559.6 KXX83147.1 - 1.6 9.3 13.1 27 5.4 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_S10 PF00450.22 KXX83148.1 - 4.5e-114 382.1 0.0 6.6e-114 381.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase GRA6 PF05084.13 KXX83148.1 - 0.084 12.8 1.2 0.15 12.0 0.9 1.6 1 1 0 1 1 1 0 Granule antigen protein (GRA6) TPR_2 PF07719.17 KXX83149.1 - 4.9e-10 38.7 2.2 0.0002 21.2 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXX83149.1 - 9.9e-10 37.9 0.0 0.0058 16.3 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_19 PF14559.6 KXX83149.1 - 3.6e-07 30.6 5.8 0.058 13.9 0.1 4.3 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXX83149.1 - 1.3e-06 28.7 9.7 0.034 15.0 0.2 5.1 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXX83149.1 - 3.4e-06 27.6 8.7 0.00016 22.2 0.6 3.8 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX83149.1 - 0.00023 21.4 5.0 0.12 12.7 0.1 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXX83149.1 - 0.05 14.0 0.0 0.84 10.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP54_N PF02881.19 KXX83149.1 - 0.096 12.9 0.2 0.21 11.9 0.2 1.6 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain TPR_9 PF13371.6 KXX83149.1 - 0.097 12.8 2.7 0.63 10.2 0.5 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TAF1_subA PF14929.6 KXX83149.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.5 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_20 PF14561.6 KXX83149.1 - 0.23 11.8 3.3 2.6 8.4 0.1 3.5 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXX83149.1 - 0.41 10.8 1.9 1.4e+02 2.9 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TGT PF01702.18 KXX83150.1 - 6.5e-38 130.8 0.0 6.2e-30 104.5 0.0 2.0 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase CN_hydrolase PF00795.22 KXX83151.1 - 1.9e-16 60.2 0.0 1.5e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KXX83152.1 - 3.8e-12 46.1 0.0 2.8e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DKCLD PF08068.12 KXX83153.1 - 3.3e-33 113.5 0.6 6e-32 109.5 0.5 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KXX83153.1 - 1.6e-23 83.7 0.3 1.5e-20 74.1 0.3 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXX83153.1 - 6.5e-23 80.7 0.3 1.2e-22 79.8 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KXX83153.1 - 4.8e-21 74.5 0.7 8.9e-21 73.7 0.7 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KXX83153.1 - 0.00057 20.1 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain SURF2 PF05477.11 KXX83153.1 - 2.7 7.6 13.3 3.9 7.1 13.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) 2-Hacid_dh_C PF02826.19 KXX83156.1 - 6.3e-44 149.4 0.1 3.9e-43 146.9 0.1 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXX83156.1 - 2.5e-05 24.0 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXX83156.1 - 0.0013 18.9 0.3 0.0099 16.1 0.1 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AOC_like PF18678.1 KXX83156.1 - 0.0043 16.7 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Allene oxide cyclase barrel like domain THDPS_N_2 PF14805.6 KXX83156.1 - 0.067 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal IlvN PF07991.12 KXX83156.1 - 0.078 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ras PF00071.22 KXX83157.1 - 9.6e-42 142.3 0.0 1.5e-41 141.7 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXX83157.1 - 8.4e-30 103.5 0.0 1.1e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXX83157.1 - 4.5e-11 42.5 0.0 1.8e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXX83157.1 - 2.7e-05 24.2 0.0 4.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXX83157.1 - 0.0012 18.2 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KXX83157.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXX83157.1 - 0.04 13.8 0.0 0.096 12.6 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KXX83157.1 - 0.052 13.3 0.0 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KXX83157.1 - 0.055 12.9 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXX83157.1 - 0.069 12.7 0.0 0.29 10.6 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KXX83157.1 - 0.07 13.4 0.0 0.099 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXX83157.1 - 0.079 13.2 0.1 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX83157.1 - 0.091 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KXX83157.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KXX83157.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXX83157.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Mannosidase_ig PF17786.1 KXX83158.1 - 1.8e-16 60.5 0.3 5.9e-16 58.8 0.3 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXX83158.1 - 1.7e-13 51.2 0.8 5.6e-13 49.5 0.0 2.3 2 1 1 3 3 3 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KXX83158.1 - 8.2e-07 28.7 0.0 2.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KXX83158.1 - 0.0022 17.9 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KXX83158.1 - 0.0071 15.5 0.2 0.027 13.6 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain adh_short PF00106.25 KXX83160.1 - 6.2e-38 130.2 0.2 8e-38 129.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX83160.1 - 9e-30 104.0 0.4 1e-29 103.7 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX83160.1 - 5.9e-12 45.9 0.5 1.6e-11 44.5 0.4 1.8 1 1 0 1 1 1 1 KR domain AraC_binding_2 PF14525.6 KXX83160.1 - 0.0043 16.8 0.9 0.041 13.6 0.2 2.0 2 0 0 2 2 2 1 AraC-binding-like domain Mur_ligase_M PF08245.12 KXX83161.1 - 0.002 18.1 0.0 3.3 7.7 0.0 2.8 2 1 0 3 3 3 2 Mur ligase middle domain Mitofilin PF09731.9 KXX83162.1 - 7.4e-168 560.2 1.4 1e-167 559.8 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Cas_DxTHG PF09455.10 KXX83162.1 - 0.031 13.9 2.2 0.038 13.6 0.8 1.7 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family DUF4363 PF14276.6 KXX83162.1 - 0.084 13.0 0.6 8.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) 4HB_MCP_1 PF12729.7 KXX83162.1 - 2.6 7.5 8.7 4.7 6.7 7.2 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction MIF4G_like_2 PF09090.11 KXX83162.1 - 3 7.2 7.9 5.6 6.3 7.9 1.3 1 0 0 1 1 1 0 MIF4G like dCache_2 PF08269.11 KXX83162.1 - 8.2 5.5 10.9 0.25 10.5 0.3 2.1 1 1 1 2 2 2 0 Cache domain ADH_N PF08240.12 KXX83163.1 - 5.7e-29 100.2 1.3 9.2e-29 99.5 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXX83163.1 - 2.7e-22 79.1 0.3 6.7e-22 77.9 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXX83163.1 - 3.3e-09 36.5 0.6 5.1e-09 35.9 0.6 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXX83163.1 - 1.4e-06 29.4 0.1 4.9e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXX83163.1 - 0.00028 20.2 1.0 0.00049 19.5 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KXX83163.1 - 0.0003 20.1 0.1 0.00078 18.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXX83163.1 - 0.00086 18.9 0.5 0.0017 17.9 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 KXX83163.1 - 0.0085 15.5 1.4 0.014 14.9 1.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyr_redox PF00070.27 KXX83163.1 - 0.037 14.6 0.5 0.64 10.6 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 KXX83163.1 - 0.037 14.1 0.2 1.2 9.2 0.4 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.14 KXX83163.1 - 0.042 12.5 1.1 0.061 12.0 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KXX83163.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mur_ligase_C PF02875.21 KXX83164.1 - 0.0024 18.1 0.0 0.03 14.5 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KXX83164.1 - 0.088 12.8 0.0 0.56 10.2 0.0 2.1 1 1 0 1 1 1 0 Mur ligase middle domain DnaJ PF00226.31 KXX83165.1 - 5.5e-17 61.6 0.5 1.5e-16 60.3 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Kinesin PF00225.23 KXX83167.1 - 4.8e-113 377.5 1.0 4.8e-113 377.5 1.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXX83167.1 - 4.9e-28 98.0 0.0 1.9e-27 96.0 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KXX83167.1 - 6e-07 29.9 0.7 6e-07 29.9 0.7 5.5 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.18 KXX83167.1 - 0.00017 21.5 52.3 0.014 15.3 14.2 4.7 1 1 2 4 4 4 3 Apolipoprotein A1/A4/E domain DUF3567 PF12091.8 KXX83167.1 - 0.02 15.0 0.9 0.083 13.0 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) ACP_PD PF04336.12 KXX83167.1 - 0.46 10.9 6.1 3.1 8.3 0.1 4.3 3 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase RRN9 PF10680.9 KXX83168.1 - 2.2e-16 59.9 2.3 4.5e-16 58.9 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor SPESP1 PF15754.5 KXX83168.1 - 0.013 14.7 1.9 0.015 14.5 0.5 1.8 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 zf-C2H2 PF00096.26 KXX83168.1 - 0.1 13.1 1.3 1.1 9.9 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Adaptin_N PF01602.20 KXX83169.1 - 2.1e-84 284.0 0.0 3.1e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXX83169.1 - 0.0028 17.7 0.2 0.038 14.0 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2312 PF10073.9 KXX83169.1 - 0.65 9.7 4.5 3.9 7.2 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) Selenoprotein_S PF06936.11 KXX83169.1 - 5.4 6.8 11.1 17 5.2 11.1 1.8 1 1 0 1 1 1 0 Selenoprotein S (SelS) LCCL PF03815.19 KXX83170.1 - 6.4e-21 74.3 0.0 9.6e-21 73.7 0.0 1.2 1 0 0 1 1 1 1 LCCL domain SAC3_GANP PF03399.16 KXX83171.1 - 1.5e-95 319.9 0.1 2.2e-95 319.4 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXX83171.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Methyltransf_12 PF08242.12 KXX83172.1 - 8.3e-15 55.3 0.0 3.2e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX83172.1 - 1e-14 55.0 0.0 2.1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX83172.1 - 4.7e-11 43.2 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX83172.1 - 1.3e-10 41.4 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX83172.1 - 4.6e-07 29.4 0.0 7.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXX83172.1 - 2.6e-06 27.3 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXX83172.1 - 0.0026 17.7 0.0 0.007 16.2 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KXX83172.1 - 0.0064 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KXX83172.1 - 0.0087 17.1 0.0 0.027 15.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Roc PF08477.13 KXX83172.1 - 0.01 16.0 0.3 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NNMT_PNMT_TEMT PF01234.17 KXX83172.1 - 0.097 11.8 0.0 9.2 5.4 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 KXX83172.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Polyketide_cyc PF03364.20 KXX83173.1 - 1e-33 116.3 0.0 1.6e-33 115.7 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KXX83173.1 - 7e-06 26.4 2.2 0.0059 16.9 0.3 2.3 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport DUF4689 PF15755.5 KXX83173.1 - 0.063 12.9 5.1 0.091 12.4 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) Glyco_hydro_43 PF04616.14 KXX83175.1 - 6.6e-17 61.7 0.0 1.5e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 EphA2_TM PF14575.6 KXX83176.1 - 0.0023 18.8 1.4 0.0041 18.0 0.0 2.2 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 KXX83176.1 - 0.027 14.4 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 DAP10 membrane protein AMP-binding PF00501.28 KXX83177.1 - 5.9e-78 262.3 0.0 7.7e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXX83177.1 - 5.6e-16 59.3 0.2 5.3e-15 56.2 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KXX83178.1 - 1e-39 136.5 27.4 3.1e-39 134.9 25.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXX83178.1 - 4.9e-10 38.9 20.8 9.8e-10 37.9 20.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3671 PF12420.8 KXX83178.1 - 0.39 10.8 8.1 2.4 8.3 0.4 4.3 3 3 1 4 4 4 0 Protein of unknown function DUF1992 PF09350.10 KXX83179.1 - 2.1e-21 75.9 0.3 5e-21 74.6 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Fungal_trans PF04082.18 KXX83180.1 - 1.2e-14 54.1 0.0 1.8e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cons_hypoth698 PF03601.14 KXX83180.1 - 0.013 14.4 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MMR_HSR1 PF01926.23 KXX83181.1 - 3.8e-07 30.2 0.0 0.031 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXX83181.1 - 7.7e-05 22.7 0.0 0.00032 20.6 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KXX83181.1 - 7.7e-05 23.1 0.6 0.0024 18.3 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain AIG1 PF04548.16 KXX83181.1 - 0.00038 19.8 0.0 0.16 11.3 0.0 2.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KXX83181.1 - 0.0046 17.0 2.7 0.53 10.3 0.0 2.8 3 0 0 3 3 2 2 Dynamin family T2SSE PF00437.20 KXX83181.1 - 0.0083 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXX83181.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 KXX83181.1 - 0.022 14.1 0.1 0.11 11.8 0.1 2.1 1 1 0 1 1 1 0 Septin IIGP PF05049.13 KXX83181.1 - 0.03 13.4 0.0 0.076 12.1 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TniB PF05621.11 KXX83181.1 - 0.033 13.6 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KXX83181.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KXX83181.1 - 0.059 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KXX83181.1 - 0.088 13.3 0.2 0.42 11.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Roc PF08477.13 KXX83181.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF4404 PF14357.6 KXX83181.1 - 0.2 12.3 1.0 1.4 9.6 1.0 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) AAA_23 PF13476.6 KXX83181.1 - 0.59 10.6 2.8 0.81 10.1 0.0 2.4 2 1 0 2 2 1 0 AAA domain Ank_4 PF13637.6 KXX83182.1 - 1.4e-12 47.9 0.0 4.2e-06 27.2 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXX83182.1 - 6.9e-11 42.6 0.0 1.4e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXX83182.1 - 2e-08 34.3 0.0 3e-07 30.6 0.0 2.8 3 0 0 3 3 2 1 Ankyrin repeat Ank_3 PF13606.6 KXX83182.1 - 2.1e-08 33.8 0.0 1.8e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat MMR_HSR1 PF01926.23 KXX83182.1 - 1.2e-06 28.6 0.3 6.1e-06 26.3 0.0 2.3 3 0 0 3 3 2 1 50S ribosome-binding GTPase Ank_5 PF13857.6 KXX83182.1 - 1.5e-06 28.3 0.0 0.00026 21.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RsgA_GTPase PF03193.16 KXX83182.1 - 2.1e-05 24.5 0.2 7.3e-05 22.7 0.0 2.0 2 0 0 2 2 1 1 RsgA GTPase Dynamin_N PF00350.23 KXX83182.1 - 8.3e-05 22.7 2.7 0.47 10.5 0.1 3.2 2 1 1 3 3 3 2 Dynamin family Septin PF00735.18 KXX83182.1 - 0.00074 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_18 PF13238.6 KXX83182.1 - 0.0014 19.2 0.2 0.0052 17.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain IIGP PF05049.13 KXX83182.1 - 0.0072 15.4 0.0 0.018 14.1 0.0 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.17 KXX83182.1 - 0.0075 16.1 0.2 0.061 13.1 0.0 2.3 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KXX83182.1 - 0.0079 16.4 0.8 0.12 12.6 0.0 2.5 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 KXX83182.1 - 0.0082 16.3 1.5 0.038 14.1 0.0 2.4 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_29 PF13555.6 KXX83182.1 - 0.0093 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KXX83182.1 - 0.012 15.0 0.0 0.18 11.1 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KXX83182.1 - 0.013 15.8 0.2 0.08 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXX83182.1 - 0.015 15.7 0.0 0.068 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KXX83182.1 - 0.021 15.3 0.4 0.17 12.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter SRP54 PF00448.22 KXX83182.1 - 0.026 14.1 0.0 0.18 11.4 0.0 2.4 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 KXX83182.1 - 0.036 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KXX83182.1 - 0.049 12.8 0.1 0.19 10.9 0.0 2.0 3 0 0 3 3 2 0 NB-ARC domain AAA_23 PF13476.6 KXX83182.1 - 0.055 14.0 0.7 3.3 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain WXG100 PF06013.12 KXX83182.1 - 0.057 13.7 1.3 0.37 11.1 2.0 2.0 2 0 0 2 2 1 0 Proteins of 100 residues with WXG AIG1 PF04548.16 KXX83182.1 - 0.058 12.7 1.8 0.18 11.1 0.0 2.6 3 1 0 3 3 3 0 AIG1 family T2SSE PF00437.20 KXX83182.1 - 0.06 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KXX83182.1 - 0.076 12.3 0.0 0.23 10.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Spore_IV_A PF09547.10 KXX83182.1 - 0.12 11.3 0.2 0.28 10.1 0.0 1.6 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) DUF3782 PF12644.7 KXX83182.1 - 0.12 12.5 0.6 0.5 10.6 0.4 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3782) MerR-DNA-bind PF09278.11 KXX83182.1 - 0.17 12.4 1.8 0.59 10.7 1.8 1.9 1 0 0 1 1 1 0 MerR, DNA binding DivIC PF04977.15 KXX83182.1 - 0.35 10.7 2.9 0.73 9.6 2.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Ank_2 PF12796.7 KXX83183.1 - 9.2e-44 147.9 6.5 1e-14 54.9 0.7 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXX83183.1 - 1.4e-35 120.9 10.4 1.6e-09 37.8 0.3 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXX83183.1 - 2e-30 104.8 2.9 2e-08 34.6 0.1 5.3 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX83183.1 - 1.3e-29 98.9 5.9 6.1e-05 23.1 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KXX83183.1 - 3e-24 84.3 18.1 0.00018 21.8 0.4 7.8 7 1 0 7 7 7 6 Ankyrin repeat Acetyltransf_10 PF13673.7 KXX83185.1 - 4.8e-07 29.8 0.0 6.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXX83185.1 - 1.5e-05 25.2 0.0 2.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXX83185.1 - 3.8e-05 24.0 0.0 6.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXX83185.1 - 0.037 14.0 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Cytochrom_B561 PF03188.16 KXX83186.1 - 1.1e-05 25.5 5.4 1.9e-05 24.8 5.4 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXX83186.1 - 3 8.0 11.9 5.8 7.1 2.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF3824 PF12868.7 KXX83186.1 - 5.3 7.7 50.0 0.028 15.1 9.8 5.2 5 0 0 5 5 5 0 Domain of unknwon function (DUF3824) MRP-L46 PF11788.8 KXX83187.1 - 1.7e-36 125.6 0.1 3.2e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KXX83187.1 - 9.6e-06 25.7 0.2 2e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L37ae PF01780.19 KXX83188.1 - 6.1e-40 135.2 7.9 6.8e-40 135.1 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KXX83188.1 - 0.00081 19.3 2.9 0.0014 18.6 2.9 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 KXX83188.1 - 0.0013 18.8 1.4 0.0019 18.3 1.4 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Sgf11 PF08209.11 KXX83188.1 - 0.034 13.7 0.4 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.6 KXX83188.1 - 0.042 14.3 1.0 1.7 9.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.13 KXX83188.1 - 0.066 13.3 2.3 0.12 12.4 2.3 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF1451 PF07295.11 KXX83188.1 - 0.069 13.2 0.4 0.094 12.8 0.4 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-BED PF02892.15 KXX83188.1 - 0.11 12.6 4.8 2.1 8.4 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 KXX83188.1 - 0.18 12.1 2.5 1.3 9.4 2.6 1.9 1 1 1 2 2 2 0 C1 domain DUF4203 PF13886.6 KXX83189.1 - 1.9e-49 168.1 27.7 3.1e-49 167.4 27.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.9 KXX83190.1 - 6.2e-38 129.5 0.0 8.5e-38 129.0 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family GCP_C_terminal PF04130.13 KXX83191.1 - 0.036 13.5 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal Mg_trans_NIPA PF05653.14 KXX83192.1 - 9e-58 195.7 8.3 9.9e-56 189.0 4.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA MerC PF03203.14 KXX83192.1 - 0.18 12.3 6.2 4.8 7.7 1.6 3.2 1 1 2 3 3 3 0 MerC mercury resistance protein DUF4149 PF13664.6 KXX83192.1 - 0.22 11.9 9.9 0.32 11.3 0.4 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) LysE PF01810.18 KXX83192.1 - 0.28 10.6 7.4 0.54 9.7 1.4 2.5 1 1 1 2 2 2 0 LysE type translocator SLC35F PF06027.12 KXX83192.1 - 0.32 10.5 5.2 0.51 9.8 0.7 2.2 1 1 1 2 2 2 0 Solute carrier family 35 TssN PF17555.2 KXX83192.1 - 0.99 8.7 4.8 1.8 7.9 4.8 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF4131 PF13567.6 KXX83192.1 - 1.7 8.3 7.2 3 7.5 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF373 PF04123.13 KXX83192.1 - 2.2 7.6 7.7 3.1 7.2 6.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) EamA PF00892.20 KXX83192.1 - 3.4 7.8 22.6 0.054 13.7 2.5 3.4 3 1 1 4 4 4 0 EamA-like transporter family Egh16-like PF11327.8 KXX83194.1 - 6.3e-56 189.7 4.8 7.8e-56 189.4 4.8 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor ADH_zinc_N PF00107.26 KXX83195.1 - 6.4e-21 74.7 0.1 9.5e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXX83195.1 - 2.9e-15 56.1 0.0 6e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXX83195.1 - 1.6e-08 35.7 0.0 3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KXX83196.1 - 3.2e-09 36.8 6.9 3.2e-09 36.8 6.9 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 KXX83196.1 - 0.5 9.9 21.8 0.058 13.0 13.8 2.1 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 KXX83196.1 - 1.8 9.6 8.2 0.3 12.1 2.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) PEMT PF04191.13 KXX83197.1 - 3e-58 194.8 9.6 1.7e-36 124.8 1.6 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 KXX83197.1 - 0.092 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KXX83197.1 - 0.11 13.1 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 SKICH domain FSH1 PF03959.13 KXX83198.1 - 1.1e-32 113.4 0.0 3e-32 112.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXX83198.1 - 0.0013 19.4 0.0 0.002 18.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX83198.1 - 0.64 9.8 2.2 2.3 8.0 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 KXX83199.1 - 1.3e-31 109.9 0.0 2.2e-30 105.9 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXX83199.1 - 1.7e-08 35.3 0.1 2.2e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXX83199.1 - 0.0007 19.5 0.5 0.0031 17.4 0.3 2.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KXX83199.1 - 0.05 13.2 0.1 0.23 11.1 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX83199.1 - 0.085 12.1 0.0 6.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KXX83200.1 - 2.1e-39 135.5 55.6 2.3e-39 135.4 47.6 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX83200.1 - 1.1e-12 47.2 12.5 1.6e-12 46.7 12.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GFA PF04828.14 KXX83201.1 - 1.7e-10 41.1 0.1 2.7e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tail_VII PF17091.5 KXX83202.1 - 0.12 12.3 4.2 0.11 12.4 1.5 2.4 2 0 0 2 2 2 0 Inovirus G7P protein Rxt3 PF08642.10 KXX83203.1 - 2.6e-43 147.8 0.0 2.6e-43 147.8 0.0 3.9 4 0 0 4 4 4 2 Histone deacetylation protein Rxt3 LCCL PF03815.19 KXX83203.1 - 1.7e-06 28.0 0.0 0.00019 21.5 0.0 2.5 2 0 0 2 2 2 2 LCCL domain Pro-kuma_activ PF09286.11 KXX83204.1 - 2e-14 54.1 0.0 1e-07 32.3 0.0 2.3 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXX83204.1 - 0.0089 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family HoxA13_N PF12284.8 KXX83205.1 - 0.17 12.5 0.9 19 5.9 0.2 2.2 2 0 0 2 2 2 0 Hox protein A13 N terminal GPI-anchored PF10342.9 KXX83206.1 - 1.3e-15 57.9 0.2 3e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pyrophosphatase PF00719.19 KXX83208.1 - 2.4e-53 180.2 0.1 3.5e-53 179.7 0.1 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sugar_tr PF00083.24 KXX83209.1 - 1.6e-115 386.6 19.9 1.9e-115 386.3 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXX83209.1 - 8.3e-23 80.9 23.2 8.3e-23 80.9 23.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 KXX83209.1 - 2.3 8.5 10.3 0.046 13.9 1.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Utp12 PF04003.12 KXX83210.1 - 2.4e-24 85.7 0.0 3.6e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Zn_clus PF00172.18 KXX83211.1 - 0.0025 17.9 11.4 0.005 16.9 1.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 KXX83214.1 - 1.3e-09 37.8 6.0 1.3e-09 37.8 6.0 2.8 2 1 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KXX83214.1 - 4.5e-07 30.1 22.9 8.2e-07 29.3 2.6 3.9 3 1 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.7 KXX83214.1 - 1.6e-05 25.1 2.9 1.6e-05 25.1 2.9 3.6 4 0 0 4 4 4 2 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXX83214.1 - 0.00041 20.1 1.9 0.00041 20.1 1.9 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 KXX83214.1 - 0.00059 19.3 2.5 0.0014 18.2 2.5 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_4 PF14447.6 KXX83214.1 - 0.0006 19.6 2.2 0.0006 19.6 2.2 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXX83214.1 - 0.00068 19.5 1.8 0.00068 19.5 1.8 3.2 4 0 0 4 4 4 1 zinc-RING finger domain zf-PHD-like PF15446.6 KXX83214.1 - 0.0011 18.7 1.5 0.0042 16.7 1.5 2.0 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-ANAPC11 PF12861.7 KXX83214.1 - 0.0015 18.6 1.1 0.0015 18.6 1.1 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXX83214.1 - 0.0034 17.2 1.6 0.0034 17.2 1.6 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXX83214.1 - 0.0035 17.3 1.1 0.0035 17.3 1.1 4.8 4 1 1 5 5 5 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXX83214.1 - 0.0048 16.7 4.5 0.0048 16.7 4.5 3.7 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 KXX83214.1 - 0.44 10.7 8.5 5.4 7.2 0.7 3.4 2 1 1 3 3 3 0 KIAA1045 RING finger zf-RING_9 PF13901.6 KXX83214.1 - 1.8 8.5 11.1 1.3 8.9 1.6 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DUF1644 PF07800.12 KXX83214.1 - 4.7 7.3 13.1 5.5 7.0 2.7 3.7 4 1 0 4 4 3 0 Protein of unknown function (DUF1644) Zn_ribbon_17 PF17120.5 KXX83214.1 - 7.5 6.3 17.8 0.026 14.2 3.3 2.6 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 KXX83214.1 - 9.2 6.2 6.6 15 5.5 0.2 3.7 3 1 1 4 4 4 0 Rad50 zinc hook motif MFS_1 PF07690.16 KXX83215.1 - 1.2e-21 77.1 37.4 1.2e-21 77.1 37.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX83215.1 - 4.2e-08 32.1 2.2 4.2e-08 32.1 2.2 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sacchrp_dh_NADP PF03435.18 KXX83216.1 - 3.2e-15 56.5 0.1 4.8e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXX83216.1 - 0.031 14.7 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RTC4 PF14474.6 KXX83216.1 - 0.2 11.8 0.0 0.56 10.4 0.0 1.7 2 0 0 2 2 2 0 RTC4-like domain PH_10 PF15411.6 KXX83218.1 - 3.8e-31 107.9 0.5 6.6e-31 107.1 0.5 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KXX83218.1 - 1.8e-12 47.8 0.0 2.9e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXX83218.1 - 7.8e-09 35.6 0.0 3.1e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KXX83218.1 - 0.00044 20.5 5.9 0.00079 19.7 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXX83218.1 - 0.0038 17.2 6.1 0.0065 16.4 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXX83218.1 - 0.0091 16.3 2.9 0.021 15.1 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXX83218.1 - 0.023 14.6 4.7 0.042 13.7 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXX83218.1 - 0.069 12.8 6.4 0.014 15.0 2.8 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KXX83218.1 - 0.072 13.0 2.8 0.14 12.1 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXX83218.1 - 0.09 12.5 4.2 0.21 11.4 4.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING-like PF08746.11 KXX83218.1 - 0.092 13.1 4.4 0.17 12.2 4.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 KXX83218.1 - 0.1 12.5 5.6 0.19 11.6 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.11 KXX83218.1 - 0.17 12.0 0.4 0.47 10.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-C3H2C3 PF17122.5 KXX83218.1 - 0.73 9.9 5.1 1.6 8.8 5.1 1.6 1 0 0 1 1 1 0 Zinc-finger Acyl_transf_3 PF01757.22 KXX83219.1 - 6.8e-31 107.6 21.3 1.3e-30 106.6 21.3 1.5 1 1 0 1 1 1 1 Acyltransferase family Med8 PF10232.9 KXX83221.1 - 1.4e-36 126.2 0.6 2e-36 125.7 0.6 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YPEB PF14620.6 KXX83221.1 - 0.043 13.2 0.1 0.059 12.7 0.1 1.2 1 0 0 1 1 1 0 YpeB sporulation GHMP_kinases_C PF08544.13 KXX83221.1 - 0.048 14.0 1.6 0.2 12.1 0.8 2.4 1 1 1 2 2 2 0 GHMP kinases C terminal Pes-10 PF07149.11 KXX83221.1 - 0.28 10.2 4.7 1.3 8.0 4.8 1.9 1 1 0 1 1 1 0 Pes-10 Sigma70_ner PF04546.13 KXX83221.1 - 0.8 9.5 9.0 5 6.9 5.9 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 KXX83221.1 - 3.1 8.2 12.3 1.8 9.0 7.8 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KXX83221.1 - 4.3 6.6 6.8 6.9 5.9 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KXX83221.1 - 5.7 4.9 8.4 0.35 8.9 3.6 1.4 2 0 0 2 2 2 0 DNA polymerase phi Sulfatase PF00884.23 KXX83222.1 - 3.7e-53 180.9 0.0 6.3e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KXX83222.1 - 1.2e-28 98.7 1.8 1.3e-27 95.3 0.6 2.4 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal PQ-loop PF04193.14 KXX83222.1 - 2.9e-23 81.4 5.9 2.5e-13 49.6 1.9 2.4 2 0 0 2 2 2 2 PQ loop repeat Phosphodiest PF01663.22 KXX83222.1 - 1.4e-07 31.4 0.0 0.0093 15.6 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KXX83222.1 - 0.0049 17.1 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KXX83222.1 - 0.16 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Chromo PF00385.24 KXX83223.1 - 3.1e-15 55.8 0.4 6.1e-15 54.9 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Trypan_PARP PF05887.11 KXX83223.1 - 0.021 14.8 7.6 0.021 14.8 7.6 2.4 4 0 0 4 4 4 0 Procyclic acidic repetitive protein (PARP) Chromo_shadow PF01393.19 KXX83223.1 - 0.088 12.9 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 Chromo shadow domain VirC1 PF07015.11 KXX83223.1 - 0.2 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein Ric8 PF10165.9 KXX83225.1 - 2.5e-112 376.3 0.0 1.3e-65 222.2 0.0 2.1 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn FerA PF08165.11 KXX83225.1 - 0.36 10.8 2.6 15 5.6 0.2 3.2 3 0 0 3 3 3 0 FerA (NUC095) domain Rif1_N PF12231.8 KXX83226.1 - 1.2e-146 488.6 0.8 1.9e-146 487.9 0.8 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldose_epim PF01263.20 KXX83227.1 - 1.4e-31 109.9 0.0 3.5e-31 108.6 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.16 KXX83228.1 - 3.1e-204 678.5 0.0 3.4e-204 678.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family p450 PF00067.22 KXX83229.1 - 5.1e-57 193.6 0.0 7.5e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GFA PF04828.14 KXX83230.1 - 1.1e-07 32.1 10.4 2.8e-05 24.4 0.1 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KXX83230.1 - 0.03 14.0 0.3 0.03 14.0 0.3 2.8 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KXX83230.1 - 0.1 12.5 0.1 0.1 12.5 0.1 3.0 4 0 0 4 4 4 0 Nudix N-terminal Rsm1 PF08600.10 KXX83230.1 - 0.12 12.5 0.3 4.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Rsm1-like DUF1857 PF08982.11 KXX83231.1 - 4.7e-25 88.2 0.0 5.3e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) AMP-binding PF00501.28 KXX83232.1 - 4.3e-71 239.7 0.0 6.6e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXX83232.1 - 8.3e-51 173.1 0.0 9.2e-26 90.5 0.0 3.5 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KXX83232.1 - 1e-14 54.6 0.2 2e-07 31.2 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXX83232.1 - 6.1e-05 23.9 0.3 0.00015 22.7 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.18 KXX83233.1 - 2.2e-35 121.9 0.0 8.2e-34 116.7 0.0 2.2 1 1 1 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KXX83233.1 - 0.00038 20.4 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_23 PF13489.6 KXX83233.1 - 0.053 13.4 0.1 0.2 11.5 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXX83233.1 - 0.12 13.2 0.0 0.5 11.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.14 KXX83234.1 - 9.3e-24 84.2 0.0 2.1e-23 83.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXX83234.1 - 1.1e-06 28.7 1.2 0.29 11.1 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXX83234.1 - 3.7e-06 26.4 2.2 0.098 11.9 0.4 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXX83234.1 - 4.3e-05 22.8 0.8 0.0029 16.7 0.1 2.7 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KXX83234.1 - 0.00018 20.3 0.1 0.034 12.9 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 KXX83234.1 - 0.00095 18.3 2.0 0.011 14.8 0.5 2.7 2 1 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXX83234.1 - 0.0018 17.6 0.1 0.0031 16.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXX83234.1 - 0.0025 18.0 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXX83234.1 - 0.0084 15.7 3.1 0.018 14.6 1.3 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXX83234.1 - 0.01 15.1 0.2 0.035 13.3 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 KXX83234.1 - 0.062 12.1 0.4 0.48 9.2 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase CbiG_N PF11760.8 KXX83234.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal GIDA PF01134.22 KXX83234.1 - 0.11 11.6 2.1 1 8.4 0.5 2.8 2 1 1 3 3 3 0 Glucose inhibited division protein A Aminotran_1_2 PF00155.21 KXX83235.1 - 8.4e-31 107.4 0.0 1.9e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II GST_C PF00043.25 KXX83236.1 - 1.9e-09 37.6 0.0 3.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXX83236.1 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXX83236.1 - 2.4e-05 24.2 0.2 4.7e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXX83236.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.6 KXX83237.1 - 1.1e-18 67.6 0.0 1.5e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXX83237.1 - 9.6e-12 45.4 0.0 1.9e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXX83237.1 - 9.7e-12 45.4 0.2 3e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXX83237.1 - 6.2e-10 39.7 0.0 1.2e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX83237.1 - 6.8e-10 38.9 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXX83237.1 - 1.8e-05 24.2 0.0 0.00016 21.1 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXX83237.1 - 0.00041 19.9 0.0 0.0029 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_19 PF04672.12 KXX83237.1 - 0.0015 18.1 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl methyltransferase MFS_1 PF07690.16 KXX83238.1 - 2.1e-34 119.0 55.5 4.1e-34 118.0 52.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXX83238.1 - 1.8e-13 49.8 13.8 3.1e-13 49.0 13.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXX83238.1 - 1.1e-07 31.1 7.2 1.1e-07 31.1 7.2 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter DUF4690 PF15756.5 KXX83238.1 - 0.0014 19.2 0.2 0.0039 17.8 0.2 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage F-box-like PF12937.7 KXX83240.1 - 0.00099 19.0 1.7 0.0023 17.8 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX83240.1 - 0.085 12.8 0.8 0.23 11.4 0.8 1.7 1 0 0 1 1 1 0 F-box domain Carb_bind PF10645.9 KXX83241.1 - 3.8e-16 59.0 11.3 3.8e-16 59.0 11.3 2.2 2 0 0 2 2 2 1 Carbohydrate binding NDUF_B12 PF08122.12 KXX83242.1 - 9.6 6.3 6.0 21 5.3 0.1 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Zn_clus PF00172.18 KXX83243.1 - 0.13 12.4 6.9 0.29 11.3 6.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KXX83244.1 - 9.6e-32 110.8 0.0 1.3e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXX83244.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 CsiD Pkinase_Tyr PF07714.17 KXX83245.1 - 6.8e-07 28.8 0.0 2.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KXX83245.1 - 4.6e-06 26.2 0.0 1.8e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF1996 PF09362.10 KXX83247.1 - 2.1e-83 279.9 1.5 2.5e-83 279.7 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gal_mutarotas_2 PF13802.6 KXX83247.1 - 0.097 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Galactose mutarotase-like HET PF06985.11 KXX83248.1 - 7.9e-06 26.3 0.1 0.00026 21.4 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RGS PF00615.19 KXX83249.1 - 1.1e-11 45.0 0.0 2e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PCI PF01399.27 KXX83250.1 - 0.00042 20.8 0.0 0.0012 19.3 0.0 1.8 1 1 0 1 1 1 1 PCI domain UQ_con PF00179.26 KXX83251.1 - 1.8e-48 163.7 0.0 2.2e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX83251.1 - 2.1e-05 24.2 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXX83251.1 - 0.0015 18.8 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXX83251.1 - 0.0074 16.2 0.0 0.013 15.3 0.0 1.4 1 1 0 1 1 1 1 UEV domain Ribosomal_L31e PF01198.19 KXX83252.1 - 1.5e-40 137.3 0.7 2.1e-40 136.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 KXX83252.1 - 0.091 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein adh_short PF00106.25 KXX83253.1 - 8.8e-54 181.9 0.0 1.2e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX83253.1 - 5.5e-37 127.6 0.1 7.1e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX83253.1 - 3e-11 43.6 0.0 4.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXX83253.1 - 0.0014 17.8 0.1 0.0032 16.6 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KXX83253.1 - 0.07 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 KXX83253.1 - 0.085 13.1 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Suf PF05843.14 KXX83254.1 - 2.8e-12 47.2 11.1 0.026 14.5 0.0 6.4 3 2 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KXX83254.1 - 3.3e-10 39.9 20.4 2.1 9.4 0.0 11.5 10 3 3 13 13 13 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXX83254.1 - 9.9e-08 31.6 2.6 0.044 14.0 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXX83254.1 - 2.8e-07 30.5 10.1 0.28 11.1 0.1 6.7 7 1 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 KXX83254.1 - 5.6e-05 22.5 0.6 5.6e-05 22.5 0.6 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXX83254.1 - 6.9e-05 23.1 6.8 0.83 10.0 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 KXX83254.1 - 0.00025 20.8 2.9 0.0029 17.3 0.2 3.5 3 2 0 3 3 3 1 26S proteasome subunit RPN7 TPR_17 PF13431.6 KXX83254.1 - 0.0043 17.3 2.8 27 5.4 0.2 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KXX83254.1 - 0.0061 15.7 17.7 0.012 14.8 0.2 6.5 3 2 4 7 7 7 1 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 KXX83254.1 - 0.062 13.4 21.8 4.9 7.5 0.0 7.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXX83254.1 - 1 9.3 12.1 49 4.0 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXX83254.1 - 2.8 8.8 5.4 92 4.0 0.0 5.6 5 1 1 6 6 5 0 Tetratricopeptide repeat ThiF PF00899.21 KXX83255.1 - 5.5e-18 65.2 0.0 9.4e-18 64.5 0.0 1.4 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KXX83255.1 - 0.006 16.8 0.1 0.24 11.6 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Fungal_trans PF04082.18 KXX83256.1 - 6.2e-23 81.2 0.1 1.1e-22 80.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXX83256.1 - 3.7e-07 30.2 12.6 6.7e-07 29.3 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDK2AP PF09806.9 KXX83256.1 - 0.33 11.0 3.3 0.58 10.2 3.3 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SUIM_assoc PF16619.5 KXX83256.1 - 0.71 10.0 10.1 0.12 12.5 2.9 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 E1-E2_ATPase PF00122.20 KXX83257.1 - 7.7e-51 172.2 0.4 2.5e-50 170.5 0.4 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KXX83257.1 - 2e-44 149.9 2.6 7e-12 45.6 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXX83257.1 - 3.9e-37 128.6 2.9 3.9e-37 128.6 2.9 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXX83257.1 - 1.3e-05 25.1 0.3 0.00031 20.6 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXX83257.1 - 0.0039 17.6 0.1 0.0079 16.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CDCA PF18484.1 KXX83257.1 - 0.036 13.9 0.2 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Cadmium carbonic anhydrase repeat DUF1656 PF07869.12 KXX83257.1 - 0.053 13.5 4.6 0.4 10.7 3.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) UBA_4 PF14555.6 KXX83258.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain p450 PF00067.22 KXX83259.1 - 1e-47 162.9 0.0 1.1e-46 159.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 KXX83259.1 - 0.36 10.6 2.0 0.99 9.2 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) ketoacyl-synt PF00109.26 KXX83260.1 - 1.9e-62 211.1 0.0 5.8e-62 209.5 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXX83260.1 - 3.1e-52 177.1 0.7 8.8e-52 175.6 0.7 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXX83260.1 - 2.8e-51 174.5 0.0 4.4e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXX83260.1 - 1.2e-44 153.1 0.0 1.8e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXX83260.1 - 3.8e-35 120.5 0.1 1.2e-34 118.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXX83260.1 - 2.5e-19 69.8 0.1 8.1e-19 68.1 0.0 2.0 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KXX83260.1 - 1.8e-17 64.6 0.0 7.6e-17 62.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXX83260.1 - 1.1e-15 57.7 0.0 3.7e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXX83260.1 - 2.8e-09 36.7 3.0 8.8e-09 35.1 0.7 2.9 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 KXX83260.1 - 2.7e-07 30.8 0.0 8.1e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KXX83260.1 - 0.00088 19.9 0.0 0.034 14.8 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 KXX83260.1 - 0.0017 18.0 1.2 0.0042 16.7 0.2 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KXX83260.1 - 0.0061 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.6 KXX83260.1 - 0.0094 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.10 KXX83260.1 - 0.012 15.5 1.8 0.029 14.2 0.3 2.6 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_12 PF08242.12 KXX83260.1 - 0.025 15.3 0.0 0.083 13.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Thiolase_N PF00108.23 KXX83260.1 - 0.078 12.3 0.1 0.23 10.8 0.1 1.8 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 KXX83260.1 - 0.18 11.6 0.3 0.55 10.0 0.0 2.0 3 0 0 3 3 1 0 Methyltransferase domain AXE1 PF05448.12 KXX83261.1 - 2.2e-11 43.0 0.0 4e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXX83261.1 - 1.1e-08 34.6 0.0 2.8e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXX83261.1 - 5e-07 30.5 0.0 7.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXX83261.1 - 0.00011 21.8 0.0 0.055 12.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXX83261.1 - 0.00021 21.0 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KXX83261.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal p450 PF00067.22 KXX83262.1 - 1.3e-40 139.6 0.0 1.7e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1674 PF07896.12 KXX83263.1 - 2.3e-18 66.4 3.7 2.3e-18 66.4 3.7 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) Pkinase PF00069.25 KXX83264.1 - 4.6e-29 101.6 0.0 1.6e-28 99.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX83264.1 - 2.1e-12 46.9 0.0 3.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXX83264.1 - 8.7e-05 21.5 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXX83264.1 - 0.15 11.9 0.1 0.49 10.3 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family AMP-binding PF00501.28 KXX83265.1 - 3.5e-89 299.3 0.0 4.6e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FAD_binding_4 PF01565.23 KXX83266.1 - 1e-21 77.1 1.9 2.1e-21 76.1 1.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXX83266.1 - 4.6e-12 45.8 0.2 7.9e-12 45.1 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KXX83266.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.22 KXX83267.1 - 1.6e-64 218.4 0.0 1.9e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_6 PF13912.6 KXX83268.1 - 0.042 13.9 0.1 0.072 13.1 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Bromodomain PF00439.25 KXX83269.1 - 4.7e-39 132.3 0.3 2.8e-22 78.6 0.1 2.8 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KXX83269.1 - 2.1e-10 40.6 2.2 2.1e-10 40.6 2.2 2.1 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation HAND PF09110.11 KXX83269.1 - 7.8 7.3 14.5 0.13 13.0 5.4 2.7 2 0 0 2 2 2 0 HAND DUF155 PF02582.14 KXX83270.1 - 1.3e-52 178.4 0.1 1.9e-52 177.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HTH_29 PF13551.6 KXX83270.1 - 0.026 14.5 0.0 0.079 13.0 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix CDC37_N PF03234.14 KXX83271.1 - 1.1e-49 168.6 1.2 1.1e-49 168.6 1.2 3.0 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KXX83271.1 - 2.9e-40 136.9 0.2 2.9e-40 136.9 0.2 2.3 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KXX83271.1 - 8.2e-33 112.5 1.8 8.2e-33 112.5 1.8 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain Cor1 PF04803.12 KXX83271.1 - 0.82 9.9 6.8 4.4 7.5 1.7 2.9 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Cpn60_TCP1 PF00118.24 KXX83272.1 - 3.9e-151 504.0 13.1 4.4e-151 503.8 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PP1_inhibitor PF05361.12 KXX83272.1 - 0.022 14.8 0.5 0.096 12.7 0.3 2.2 1 1 1 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor EAL PF00563.20 KXX83272.1 - 0.027 14.0 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 EAL domain Nitro_FeMo-Co PF02579.17 KXX83272.1 - 0.029 14.7 0.1 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor AAA_10 PF12846.7 KXX83272.1 - 0.14 11.0 2.9 1.7 7.5 0.4 2.4 1 1 1 2 2 2 0 AAA-like domain HMG_box PF00505.19 KXX83273.1 - 6.6e-10 39.3 0.8 6.6e-10 39.3 0.8 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXX83273.1 - 1.3e-05 25.7 2.4 1.3e-05 25.7 2.4 2.3 2 1 1 3 3 3 1 HMG-box domain DUF3987 PF13148.6 KXX83273.1 - 4 6.4 10.0 2.1 7.3 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF3535 PF12054.8 KXX83274.1 - 1.4e-130 436.4 0.1 8.3e-130 433.9 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KXX83274.1 - 2.7e-66 223.7 0.0 6.4e-66 222.4 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.22 KXX83274.1 - 1.3e-13 49.9 11.2 0.0051 17.0 0.0 8.8 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 KXX83274.1 - 3.9e-09 36.8 6.9 0.00014 22.2 0.0 6.6 6 0 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KXX83274.1 - 5.5e-06 26.9 0.3 1.2 9.8 0.0 4.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 KXX83274.1 - 0.06 13.1 0.6 11 5.7 0.1 3.3 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 KXX83274.1 - 0.12 13.0 14.1 13 6.4 0.0 7.4 9 0 0 9 9 9 0 HEAT-like repeat TAF6_C PF07571.13 KXX83274.1 - 0.15 12.4 0.4 96 3.4 0.0 5.0 6 1 1 7 7 7 0 TAF6 C-terminal HEAT repeat domain Clr5 PF14420.6 KXX83275.1 - 9.6e-19 67.4 0.9 2.1e-18 66.3 0.9 1.6 1 0 0 1 1 1 1 Clr5 domain Amidohydro_2 PF04909.14 KXX83276.1 - 2.2e-31 109.7 0.3 2.8e-31 109.4 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KXX83276.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 TatD related DNase SMC_N PF02463.19 KXX83277.1 - 1e-56 191.9 32.7 2.4e-56 190.6 32.7 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXX83277.1 - 1.7e-25 89.6 0.0 7.6e-25 87.5 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KXX83277.1 - 1.2e-18 68.4 7.7 1.2e-18 68.4 7.7 8.1 2 2 3 5 5 3 1 AAA domain AAA_21 PF13304.6 KXX83277.1 - 7.7e-15 55.5 14.3 2.5e-08 34.1 0.8 3.8 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXX83277.1 - 1.1e-08 35.3 72.0 1.3e-06 28.4 24.9 5.2 2 2 1 3 3 2 2 AAA ATPase domain SbcCD_C PF13558.6 KXX83277.1 - 0.00045 20.4 0.1 0.0026 18.0 0.1 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXX83277.1 - 0.003 17.3 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KXX83277.1 - 0.4 11.2 0.0 0.4 11.2 0.0 6.5 3 2 0 3 3 1 0 ABC transporter CCP_MauG PF03150.14 KXX83277.1 - 1.1 9.9 10.2 3.4 8.3 0.0 4.0 3 1 0 4 4 4 0 Di-haem cytochrome c peroxidase IR1-M PF12185.8 KXX83277.1 - 1.5 8.8 5.4 4.7 7.2 0.1 3.8 3 0 0 3 3 3 0 Nup358/RanBP2 E3 ligase domain DUF1359 PF07097.11 KXX83277.1 - 2.1 8.6 7.5 1.1 9.6 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1359) peroxidase PF00141.23 KXX83278.1 - 1.3e-20 74.1 0.1 2.2e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 Peroxidase HET PF06985.11 KXX83278.1 - 0.0011 19.4 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PSI_PSAK PF01241.18 KXX83278.1 - 0.17 12.0 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK p450 PF00067.22 KXX83279.1 - 4e-39 134.7 0.0 5.2e-39 134.3 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Noc2 PF03715.13 KXX83280.1 - 6.2e-129 429.5 0.1 1.3e-128 428.5 0.1 1.5 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KXX83280.1 - 5.1e-07 28.4 0.5 5.1e-07 28.4 0.5 3.5 2 2 1 3 3 3 1 Nop14-like family DUF726 PF05277.12 KXX83281.1 - 1.3e-119 399.2 0.5 1.7e-119 398.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KXX83281.1 - 3.5e-05 24.0 0.0 7.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 KXX83281.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain DUF5476 PF17570.2 KXX83281.1 - 9.9 6.6 7.7 0.82 10.1 0.5 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5476) GFA PF04828.14 KXX83282.1 - 4.2e-17 62.3 4.0 7.6e-17 61.4 4.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Gln-synt_C PF00120.24 KXX83283.1 - 2.8e-14 52.9 0.0 3.1e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXX83283.1 - 7.7e-13 48.0 0.0 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RNase_P_p30 PF01876.16 KXX83285.1 - 7.9e-54 182.4 0.0 5.9e-53 179.5 0.0 1.9 1 1 0 1 1 1 1 RNase P subunit p30 DUF155 PF02582.14 KXX83286.1 - 3.6e-55 186.8 0.1 6.9e-55 185.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 KXX83286.1 - 0.098 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Collectrin PF16959.5 KXX83286.1 - 0.15 11.8 0.3 13 5.5 0.2 2.3 2 0 0 2 2 2 0 Renal amino acid transporter LBP_BPI_CETP_C PF02886.17 KXX83286.1 - 0.17 11.3 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain SWIRM-assoc_2 PF16496.5 KXX83287.1 - 0.00018 20.5 0.3 0.00018 20.5 0.3 3.2 3 1 1 4 4 4 1 SWIRM-associated domain at the N-terminal AT_hook PF02178.19 KXX83287.1 - 0.21 11.5 16.6 0.79 9.8 2.4 4.2 3 0 0 3 3 3 0 AT hook motif FTR PF01913.18 KXX83287.1 - 0.23 11.4 5.2 0.57 10.1 5.2 1.6 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase MMM1 PF10296.9 KXX83288.1 - 4.5e-05 22.7 0.0 0.00013 21.1 0.0 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 SPX PF03105.19 KXX83288.1 - 0.22 11.4 7.2 0.38 10.6 7.2 1.3 1 0 0 1 1 1 0 SPX domain CCDC106 PF15794.5 KXX83288.1 - 0.69 9.6 4.0 0.52 10.0 0.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 VPS28 PF03997.12 KXX83289.1 - 1.4e-67 227.1 0.1 1.6e-67 226.8 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein TAF8_C PF10406.9 KXX83289.1 - 0.13 12.8 0.2 5.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Pkinase PF00069.25 KXX83292.1 - 1.6e-17 63.7 0.0 3.3e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX83292.1 - 7.2e-06 25.5 0.0 7.1e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KXX83292.1 - 0.039 12.9 0.0 7 5.5 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 KXX83293.1 - 5.2e-16 58.8 0.0 1.7e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX83293.1 - 0.0033 16.7 0.0 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase HET PF06985.11 KXX83295.1 - 4.4e-22 79.0 0.0 8e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 KXX83296.1 - 4.2e-43 147.8 0.0 3.4e-37 128.3 0.0 2.8 3 0 0 3 3 3 2 Cytochrome P450 Herpes_UL7 PF01677.16 KXX83297.1 - 0.032 14.0 0.4 0.051 13.3 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL7 like Vps35 PF03635.17 KXX83297.1 - 0.15 10.6 0.1 0.18 10.2 0.1 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 PAF-AH_p_II PF03403.13 KXX83297.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ank_2 PF12796.7 KXX83298.1 - 0.00077 20.0 0.0 0.0016 19.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX83298.1 - 0.001 19.6 0.0 1.1 10.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX83298.1 - 0.037 14.6 0.2 32 5.5 0.1 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 KXX83299.1 - 1.2e-20 73.9 0.5 1.4e-08 35.2 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXX83299.1 - 1.8e-15 57.1 1.6 0.00018 22.0 0.2 4.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXX83299.1 - 9.4e-13 47.1 2.4 0.0028 18.0 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXX83299.1 - 1.9e-12 47.2 0.3 7.9e-06 26.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXX83299.1 - 7e-08 32.6 9.8 0.034 14.6 0.1 6.0 7 0 0 7 7 7 3 Ankyrin repeat Peptidase_M28 PF04389.17 KXX83300.1 - 3.6e-40 137.8 0.1 5.4e-40 137.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXX83300.1 - 2.8e-13 49.7 0.8 7.1e-13 48.4 0.8 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXX83300.1 - 5.4e-05 23.0 0.1 0.00015 21.5 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 HET PF06985.11 KXX83301.1 - 0.014 15.7 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Peptidase_M13_N PF05649.13 KXX83302.1 - 3.2e-56 191.6 0.3 4.8e-56 191.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KXX83302.1 - 8.4e-54 182.3 1.6 1.2e-53 181.8 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M13 DUF1330 PF07045.11 KXX83302.1 - 0.0048 17.2 0.4 0.37 11.2 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1330) CLN3 PF02487.17 KXX83303.1 - 4.9e-160 532.9 0.5 5.7e-160 532.7 0.5 1.0 1 0 0 1 1 1 1 CLN3 protein Keratin_assoc PF09775.9 KXX83303.1 - 6.7 6.4 6.6 0.64 9.7 1.7 1.8 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 DUF1741 PF08427.10 KXX83307.1 - 1e-89 300.2 0.3 1.9e-89 299.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.20 KXX83308.1 - 8.6e-19 67.8 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CPT_N PF16484.5 KXX83308.1 - 0.032 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus SWI-SNF_Ssr4 PF08549.10 KXX83308.1 - 0.29 9.7 7.7 0.34 9.5 7.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Macoilin PF09726.9 KXX83308.1 - 1.2 7.6 3.2 1.4 7.4 3.2 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 KXX83308.1 - 2.4 6.8 8.8 2.7 6.6 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ecl1 PF12855.7 KXX83308.1 - 4.5 8.4 25.1 6.2 8.0 25.1 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins MgsA_C PF12002.8 KXX83309.1 - 6.3e-61 205.2 0.1 1.8e-60 203.7 0.0 1.7 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KXX83309.1 - 7.1e-24 84.0 0.1 1.6e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KXX83309.1 - 1e-12 48.6 0.0 2.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXX83309.1 - 4.9e-09 36.1 0.0 9.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KXX83309.1 - 9.2e-07 28.7 0.1 3.8e-05 23.4 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KXX83309.1 - 1.1e-05 25.8 5.7 0.0034 17.8 0.1 3.3 1 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXX83309.1 - 8.8e-05 22.8 0.3 0.00047 20.4 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXX83309.1 - 0.00017 21.6 0.3 0.013 15.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXX83309.1 - 0.00036 20.6 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXX83309.1 - 0.00038 19.9 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXX83309.1 - 0.0051 16.7 0.0 0.1 12.5 0.0 2.6 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXX83309.1 - 0.0053 15.9 0.0 0.012 14.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KXX83309.1 - 0.0073 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain ResIII PF04851.15 KXX83309.1 - 0.014 15.4 0.2 0.9 9.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXX83309.1 - 0.016 15.5 0.1 0.19 12.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain SKI PF01202.22 KXX83309.1 - 0.027 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 KXX83309.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXX83309.1 - 0.077 13.2 0.7 0.22 11.7 0.7 1.8 1 1 0 1 1 1 0 AAA domain zf-WRNIP1_ubi PF18279.1 KXX83309.1 - 0.084 13.6 0.6 0.2 12.3 0.1 2.0 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain TniB PF05621.11 KXX83309.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Cytidylate_kin PF02224.18 KXX83309.1 - 0.13 12.0 0.2 0.66 9.7 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 KXX83309.1 - 0.13 12.8 0.1 0.54 10.8 0.1 2.0 2 0 0 2 2 2 0 ABC transporter CPT PF07931.12 KXX83309.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Annexin PF00191.20 KXX83310.1 - 1.5e-67 223.6 5.0 3.9e-20 71.7 0.0 4.2 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 KXX83310.1 - 0.086 12.6 1.8 31 4.4 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3574) Cpn60_TCP1 PF00118.24 KXX83312.1 - 2.3e-158 527.9 5.8 2.6e-158 527.7 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 KXX83312.1 - 0.18 12.0 3.1 7.1 6.8 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain GTP_EFTU PF00009.27 KXX83313.1 - 1.1e-45 155.6 0.0 1.9e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KXX83313.1 - 1.1e-24 86.5 0.7 2.3e-24 85.5 0.7 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KXX83313.1 - 1.1e-07 32.2 0.1 2.6e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXX83313.1 - 5.1e-07 29.8 0.0 3e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KXX83313.1 - 8.2e-06 26.1 0.0 2.8e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 KXX83313.1 - 0.0011 19.2 0.0 0.052 13.8 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXX83313.1 - 0.02 14.3 0.0 4.2 6.8 0.0 2.4 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit cobW PF02492.19 KXX83313.1 - 0.065 12.8 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain EamA PF00892.20 KXX83314.1 - 0.0011 19.1 15.9 0.07 13.3 15.9 2.1 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KXX83314.1 - 0.04 13.9 3.6 0.061 13.4 3.6 1.4 1 0 0 1 1 1 0 Putative transmembrane family 234 TFIIA_gamma_C PF02751.14 KXX83315.1 - 1e-23 83.2 0.5 1.7e-23 82.5 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KXX83315.1 - 1.4e-22 79.5 0.3 1.9e-22 79.0 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MoCF_biosynth PF00994.24 KXX83316.1 - 3.3e-56 189.0 1.9 2.3e-30 105.1 0.1 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KXX83316.1 - 3.7e-40 137.3 6.1 6.2e-40 136.5 6.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KXX83316.1 - 4.6e-17 62.0 0.3 2.3e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 KXX83316.1 - 7.7 5.8 20.5 11 5.3 20.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MAS20 PF02064.15 KXX83317.1 - 5.6e-44 149.4 1.0 7e-44 149.0 1.0 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF2048 PF09752.9 KXX83317.1 - 0.026 13.7 0.1 0.031 13.4 0.1 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DUF4381 PF14316.6 KXX83317.1 - 0.032 14.5 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TipAS PF07739.13 KXX83317.1 - 0.033 14.7 4.9 12 6.5 0.0 2.2 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain LapA_dom PF06305.11 KXX83317.1 - 0.04 13.7 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NCE101 PF11654.8 KXX83317.1 - 0.086 12.6 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 AP-5_subunit_s1 PF15001.6 KXX83317.1 - 0.14 12.1 0.9 0.18 11.8 0.9 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF4230 PF14014.6 KXX83317.1 - 0.29 11.4 2.5 0.81 9.9 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) Wyosine_form PF08608.12 KXX83318.1 - 1.8e-24 85.8 0.0 3.9e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KXX83318.1 - 3.9e-21 76.2 0.0 1.2e-20 74.5 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KXX83318.1 - 3e-09 37.2 0.0 1.8e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin DNA_pol_alpha_N PF12254.8 KXX83318.1 - 0.031 14.4 0.0 6.4 6.9 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal GHMP_kinases_C PF08544.13 KXX83318.1 - 0.14 12.5 0.0 4.1 7.8 0.0 2.8 2 1 0 2 2 2 0 GHMP kinases C terminal p450 PF00067.22 KXX83319.1 - 4.1e-18 65.4 0.0 1.8e-10 40.2 0.0 2.4 2 1 1 3 3 3 2 Cytochrome P450 Metallophos PF00149.28 KXX83320.1 - 3.6e-38 132.1 0.5 5.7e-38 131.5 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXX83320.1 - 0.12 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Exo84_C PF16528.5 KXX83321.1 - 8e-79 264.2 0.7 8e-79 264.2 0.7 2.2 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KXX83321.1 - 7.7e-17 61.1 1.8 7.7e-17 61.1 1.8 2.8 4 0 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.11 KXX83321.1 - 0.077 13.1 3.0 1.8 8.7 0.1 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.6 KXX83321.1 - 0.63 10.5 2.8 3.6 8.1 0.0 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prominin PF05478.11 KXX83321.1 - 1 7.2 3.6 2.9 5.7 0.1 2.3 2 0 0 2 2 2 0 Prominin APG6_N PF17675.1 KXX83321.1 - 3.8 8.0 12.8 1.9 9.0 3.1 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region ARID PF01388.21 KXX83322.1 - 1.3e-18 67.4 0.1 6.3e-18 65.2 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain SUIM_assoc PF16619.5 KXX83322.1 - 0.0027 17.7 8.5 0.0027 17.7 8.5 2.5 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 V-ATPase_H_N PF03224.14 KXX83322.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 V-ATPase subunit H SPX PF03105.19 KXX83322.1 - 0.36 10.7 22.0 0.092 12.6 3.2 2.1 2 0 0 2 2 2 0 SPX domain Spt20 PF12090.8 KXX83322.1 - 2.5 7.7 27.8 0.15 11.6 20.0 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 KXX83322.1 - 3.2 7.6 24.7 0.27 11.2 14.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Slu7 PF11708.8 KXX83322.1 - 4.2 7.1 10.4 0.18 11.5 3.5 1.9 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Ndc1_Nup PF09531.10 KXX83322.1 - 5.6 5.5 16.1 0.024 13.4 3.9 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 KXX83322.1 - 7.1 6.1 13.2 0.16 11.5 3.5 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist EPL1 PF10513.9 KXX83322.1 - 8 6.8 12.3 5.6 7.3 5.5 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Hydin_ADK PF17213.3 KXX83322.1 - 9.8 6.4 14.3 2.3 8.4 5.1 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain SAP PF02037.27 KXX83323.1 - 1.2e-12 47.2 0.2 2.1e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 SAP domain GATase PF00117.28 KXX83324.1 - 8.4e-48 162.7 0.0 1.1e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KXX83324.1 - 1.4e-46 157.5 0.0 2.3e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KXX83324.1 - 6.3e-06 26.1 0.2 0.00059 19.6 0.2 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KXX83324.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family F-box-like PF12937.7 KXX83325.1 - 1.3e-08 34.5 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXX83325.1 - 2e-06 27.5 0.0 4.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 KXX83325.1 - 0.0023 17.7 14.7 0.075 13.0 2.4 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KXX83326.1 - 0.63 10.3 19.4 6.7 7.0 3.4 3.8 4 0 0 4 4 4 0 FYVE-type zinc finger HypA PF01155.19 KXX83326.1 - 1.4 9.0 23.7 0.21 11.6 1.1 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sar8_2 PF03058.14 KXX83326.1 - 2.4 8.7 11.8 0.6 10.7 2.1 2.8 2 1 0 2 2 2 0 Sar8.2 family Asp PF00026.23 KXX83327.1 - 3.4e-08 33.3 0.8 2.1e-07 30.7 0.8 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Ist1 PF03398.14 KXX83328.1 - 1.1e-63 214.0 3.4 1.4e-63 213.7 3.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway zf-CCHC_2 PF13696.6 KXX83329.1 - 4.9e-13 48.6 7.4 1.9e-06 27.6 1.4 2.5 2 0 0 2 2 2 2 Zinc knuckle eIF3g PF12353.8 KXX83329.1 - 0.36 11.2 5.2 0.8 10.1 2.7 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Clat_adaptor_s PF01217.20 KXX83330.1 - 4.8e-57 191.9 2.0 5.3e-57 191.7 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Serinc PF03348.15 KXX83331.1 - 3.9e-164 546.7 6.9 4.4e-164 546.5 6.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.20 KXX83332.1 - 1.9e-139 464.5 0.0 2.2e-139 464.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXX83332.1 - 6.8e-07 28.6 0.0 1.8e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXX83332.1 - 4.9e-06 26.0 0.0 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KXX83332.1 - 3.8e-05 22.4 0.1 0.0001 21.0 0.1 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KXX83332.1 - 5e-05 22.8 0.1 0.00014 21.3 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 KXX83332.1 - 0.024 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein AAA PF00004.29 KXX83333.1 - 2.4e-37 128.3 0.0 4e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXX83333.1 - 5.4e-11 42.1 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KXX83333.1 - 4.3e-06 26.8 0.0 1.1e-05 25.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KXX83333.1 - 9.4e-06 26.1 0.9 0.00041 20.8 0.0 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KXX83333.1 - 1.2e-05 25.3 0.1 0.00013 22.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXX83333.1 - 1.2e-05 25.6 0.1 0.0013 19.0 0.1 3.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KXX83333.1 - 1.8e-05 24.6 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXX83333.1 - 6e-05 23.2 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KXX83333.1 - 0.00061 19.2 0.2 0.0016 17.8 0.2 1.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXX83333.1 - 0.00099 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXX83333.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KXX83333.1 - 0.0018 18.4 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXX83333.1 - 0.002 17.6 0.0 2.8 7.3 0.0 2.8 2 1 0 3 3 3 2 Bacterial TniB protein AAA_18 PF13238.6 KXX83333.1 - 0.0029 18.1 0.0 0.0071 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXX83333.1 - 0.0038 17.5 0.1 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXX83333.1 - 0.0051 16.8 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 NACHT domain Sigma54_activ_2 PF14532.6 KXX83333.1 - 0.0065 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.6 KXX83333.1 - 0.0065 16.1 2.2 0.026 14.1 0.2 2.7 3 1 1 4 4 4 1 AAA domain Rad17 PF03215.15 KXX83333.1 - 0.0092 15.9 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 KXX83333.1 - 0.015 15.1 0.0 0.028 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXX83333.1 - 0.023 13.9 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KXX83333.1 - 0.027 14.2 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KXX83333.1 - 0.034 13.3 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KXX83333.1 - 0.037 14.6 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KXX83333.1 - 0.054 13.4 0.0 0.2 11.5 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KXX83333.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KXX83333.1 - 0.063 12.6 0.2 0.2 10.9 0.0 1.9 2 0 0 2 2 1 0 Zeta toxin AAA_7 PF12775.7 KXX83333.1 - 0.072 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KXX83333.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KXX83333.1 - 0.077 13.4 0.5 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 KXX83333.1 - 0.1 12.2 0.0 0.64 9.7 0.0 2.3 2 1 0 3 3 3 0 Guanylate kinase TIP49 PF06068.13 KXX83333.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KXX83333.1 - 0.18 11.1 0.0 0.65 9.3 0.0 1.8 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.22 KXX83333.1 - 0.24 10.6 0.0 0.7 9.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Csm1 PF12539.8 KXX83334.1 - 4.5e-32 110.5 0.0 9.5e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 BBP1_C PF15272.6 KXX83334.1 - 0.00018 21.4 1.2 0.00035 20.5 1.2 1.5 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal EzrA PF06160.12 KXX83334.1 - 0.0027 15.9 7.9 0.0042 15.3 7.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF5094 PF17015.5 KXX83334.1 - 0.0046 17.1 0.0 0.0046 17.1 0.0 3.6 3 1 0 3 3 2 1 Domain of unknown function (DUF5094) Spc7 PF08317.11 KXX83334.1 - 0.0064 15.4 11.2 0.0064 15.4 11.2 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Cob_adeno_trans PF01923.18 KXX83334.1 - 0.014 15.6 2.1 0.038 14.1 2.1 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase ADIP PF11559.8 KXX83334.1 - 0.2 11.8 12.7 0.24 11.5 10.8 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KXX83334.1 - 0.39 10.9 4.4 0.82 9.9 4.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2570 PF10828.8 KXX83334.1 - 0.52 10.2 7.4 1.4 8.8 7.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Atg14 PF10186.9 KXX83334.1 - 1.8 7.6 16.5 0.16 11.0 6.7 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 KXX83334.1 - 2.2 7.5 13.0 0.85 8.9 9.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) XhlA PF10779.9 KXX83334.1 - 3.6 7.9 7.2 2.9 8.2 3.0 2.6 1 1 1 2 2 2 0 Haemolysin XhlA CC2-LZ PF16516.5 KXX83334.1 - 4.2 7.8 12.9 0.12 12.7 5.3 2.5 2 1 0 2 2 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMPIT PF07851.13 KXX83334.1 - 5.7 6.1 6.1 9.7 5.3 6.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein TFIID-18kDa PF02269.16 KXX83335.1 - 9.5e-31 105.7 2.1 9.1e-30 102.5 0.2 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KXX83335.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Zn_clus PF00172.18 KXX83336.1 - 1.3e-09 38.0 9.9 2.4e-09 37.1 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXX83336.1 - 3.4e-06 26.1 2.4 4.6e-06 25.7 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VHS PF00790.19 KXX83337.1 - 1.7e-20 73.3 0.0 2e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KXX83337.1 - 3.4e-07 30.5 0.7 1.1e-06 28.9 0.7 1.9 1 0 0 1 1 1 1 GAT domain YliH PF10799.8 KXX83337.1 - 0.1 12.5 0.4 0.27 11.2 0.4 1.8 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) DUF3530 PF12048.8 KXX83337.1 - 1.1 8.7 10.7 0.047 13.1 4.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) BRE1 PF08647.11 KXX83337.1 - 4 7.6 11.7 1.3 9.2 8.1 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase zf-CHY PF05495.12 KXX83338.1 - 1e-10 41.9 10.5 1e-10 41.9 10.5 3.3 2 1 0 2 2 2 1 CHY zinc finger RWD PF05773.22 KXX83338.1 - 0.0014 18.9 0.1 0.0077 16.5 0.0 2.1 2 0 0 2 2 2 1 RWD domain Mu-like_Com PF10122.9 KXX83338.1 - 0.019 14.4 0.1 0.13 11.7 0.1 2.6 1 0 0 1 1 1 0 Mu-like prophage protein Com IL2 PF00715.17 KXX83338.1 - 0.083 12.8 0.6 0.19 11.7 0.6 1.5 1 0 0 1 1 1 0 Interleukin 2 tRNA-synt_His PF13393.6 KXX83338.1 - 0.18 11.0 2.7 0.39 10.0 2.7 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zinc_ribbon_4 PF13717.6 KXX83338.1 - 7.9 6.5 11.9 22 5.1 0.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain HECT PF00632.25 KXX83339.1 - 1.4e-62 211.9 0.0 3.9e-62 210.5 0.0 1.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KXX83339.1 - 9.6e-22 77.0 1.9 1.9e-21 76.0 1.9 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 KXX83340.1 - 1.8e-33 114.9 7.9 1.1e-27 96.3 0.6 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXX83340.1 - 2.6e-07 30.8 19.8 2.7e-06 27.5 3.5 4.0 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXX83340.1 - 6e-07 29.7 1.9 6e-07 29.7 1.9 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KXX83340.1 - 0.0031 17.9 22.1 0.22 12.0 1.2 4.9 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-DBF PF07535.12 KXX83340.1 - 0.1 12.7 0.1 0.1 12.7 0.1 4.0 5 0 0 5 5 5 0 DBF zinc finger AKAP95 PF04988.12 KXX83340.1 - 0.11 12.7 2.5 3.5 7.9 0.1 3.2 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 KXX83340.1 - 0.46 11.5 26.7 2.2 9.3 0.4 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger KCH PF16944.5 KXX83341.1 - 9.2e-97 323.7 7.8 1.1e-96 323.5 7.8 1.1 1 0 0 1 1 1 1 Fungal potassium channel CorA PF01544.18 KXX83342.1 - 3.4e-09 36.4 0.2 4.9e-09 35.9 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein tRNA-synt_2 PF00152.20 KXX83343.1 - 5.8e-72 242.4 0.8 7.5e-72 242.1 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXX83343.1 - 1e-11 44.6 0.1 1.9e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXX83343.1 - 4e-09 36.3 0.0 0.00029 20.4 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ArfGap PF01412.18 KXX83344.1 - 6.4e-40 135.9 0.4 9.7e-40 135.3 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UCH PF00443.29 KXX83345.1 - 6.1e-34 117.7 0.0 8.7e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXX83345.1 - 2.6e-08 33.8 0.0 1.7e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KXX83345.1 - 7.3e-07 29.7 0.0 1.3e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain zf-C3HC PF07967.13 KXX83346.1 - 1.2e-38 132.2 0.1 9.2e-38 129.3 0.0 2.0 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 KXX83346.1 - 2.5e-15 56.4 0.3 1.9e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.21 KXX83346.1 - 0.0024 18.5 0.2 0.029 15.0 0.2 2.2 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-RING_4 PF14570.6 KXX83347.1 - 5.6e-20 70.9 12.0 9.5e-20 70.1 12.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KXX83347.1 - 3.3e-09 36.4 0.0 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KXX83347.1 - 8.7e-07 28.7 10.5 1.6e-06 27.9 10.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXX83347.1 - 0.0033 16.8 2.5 0.0033 16.8 2.5 4.1 4 0 0 4 4 4 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KXX83347.1 - 0.0079 16.5 13.7 0.0079 16.5 13.7 1.7 2 0 0 2 2 1 1 Ring finger domain Nup35_RRM_2 PF14605.6 KXX83347.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HNOBA PF07701.14 KXX83347.1 - 0.074 12.5 3.3 0.28 10.6 0.1 2.5 2 0 0 2 2 2 0 Heme NO binding associated SET_assoc PF11767.8 KXX83347.1 - 0.083 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 KXX83347.1 - 0.1 12.4 11.0 0.24 11.3 8.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXX83347.1 - 0.11 12.4 10.1 0.22 11.4 10.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KXX83347.1 - 0.34 11.1 6.5 0.73 10.0 6.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.11 KXX83347.1 - 0.43 10.5 7.0 0.91 9.5 7.0 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 KXX83347.1 - 1.1 9.4 6.0 2.8 8.1 6.0 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 KXX83347.1 - 3.7 7.6 13.4 6.9 6.7 13.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FYVE_2 PF02318.16 KXX83347.1 - 8.5 6.6 16.5 1.3 9.3 7.0 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger FAD_binding_1 PF00667.20 KXX83348.1 - 1.2e-65 221.2 0.0 2.4e-65 220.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXX83348.1 - 2.4e-09 37.8 0.0 7.3e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KXX83348.1 - 3.1e-09 37.1 0.0 7.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KXX83348.1 - 4.3e-08 33.4 0.3 2.1e-07 31.2 0.2 2.3 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KXX83348.1 - 0.0006 19.7 0.1 0.0028 17.6 0.1 2.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1-E2_ATPase PF00122.20 KXX83349.1 - 2.5e-50 170.5 1.2 3.6e-50 170.0 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KXX83349.1 - 1.8e-38 130.8 2.3 9.3e-12 45.2 0.0 5.2 4 1 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXX83349.1 - 1.7e-37 129.8 0.5 3.8e-37 128.6 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXX83349.1 - 1.3e-05 25.7 0.0 3.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXX83349.1 - 0.00019 21.3 0.0 0.00094 19.0 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Poly_export PF02563.16 KXX83349.1 - 0.0037 17.5 0.0 2.6 8.3 0.0 2.7 2 0 0 2 2 2 2 Polysaccharide biosynthesis/export protein Diphtheria_C PF02763.14 KXX83350.1 - 0.16 11.7 2.0 0.22 11.2 2.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, C domain Fe-ADH PF00465.19 KXX83351.1 - 1.4e-103 346.5 0.0 1.7e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXX83351.1 - 2.9e-15 56.6 0.0 1.6e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KXX83351.1 - 0.0027 17.4 0.1 0.0043 16.8 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein APH PF01636.23 KXX83352.1 - 6.9e-11 42.5 0.1 1.1e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sec3_C PF09763.9 KXX83353.1 - 1.9e-259 862.8 0.0 2.5e-259 862.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KXX83353.1 - 3.6e-28 97.5 0.0 6.5e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KXX83353.1 - 0.0074 16.6 2.1 0.021 15.2 0.0 2.7 3 0 0 3 3 3 1 Sec3 exocyst complex subunit Vps52 PF04129.12 KXX83353.1 - 0.055 12.2 4.0 0.12 11.1 0.3 2.3 2 0 0 2 2 2 0 Vps52 / Sac2 family DUF2018 PF09442.10 KXX83353.1 - 0.068 14.2 0.1 0.26 12.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) HECT PF00632.25 KXX83354.1 - 1.4e-76 257.9 0.0 2.6e-76 257.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) BUD22 PF09073.10 KXX83354.1 - 0.00049 19.6 13.2 0.00049 19.6 13.2 3.8 3 1 1 4 4 4 1 BUD22 CLASP_N PF12348.8 KXX83354.1 - 0.015 14.9 0.2 0.08 12.5 0.0 2.2 3 0 0 3 3 3 0 CLASP N terminal Arm PF00514.23 KXX83354.1 - 0.024 14.7 5.6 7.8 6.7 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXX83354.1 - 0.048 13.9 1.7 9 6.9 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat COPI_C PF06957.11 KXX83354.1 - 7.2 5.3 6.3 18 3.9 6.3 1.7 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ESCRT-II PF05871.12 KXX83356.1 - 2.2e-40 138.2 0.2 2e-33 115.6 0.0 2.2 1 1 1 2 2 2 2 ESCRT-II complex subunit Glyco_hydro_7 PF00840.20 KXX83357.1 - 1.9e-203 676.1 19.1 2.1e-203 675.9 19.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fapy_DNA_glyco PF01149.24 KXX83358.1 - 2.9e-34 118.2 0.0 4.8e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KXX83358.1 - 2.2e-21 75.6 0.0 4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KXX83358.1 - 0.012 14.4 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 KXX83358.1 - 0.083 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 ATP-synt_C PF00137.21 KXX83359.1 - 1.4e-24 86.2 35.5 4.5e-15 55.7 10.9 3.0 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 KXX83359.1 - 0.12 11.7 0.2 0.12 11.7 0.2 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HNH_2 PF13391.6 KXX83360.1 - 8.2e-08 32.3 0.0 2.3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease DDHD PF02862.17 KXX83360.1 - 4.9 7.3 9.0 27 4.8 7.8 2.1 2 0 0 2 2 2 0 DDHD domain PRCC PF10253.9 KXX83360.1 - 8 7.2 19.5 5.5 7.7 16.0 2.0 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting HSP70 PF00012.20 KXX83363.1 - 5.3e-265 880.3 14.4 6e-265 880.1 14.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXX83363.1 - 1.6e-16 60.0 2.4 1.1e-14 54.0 2.4 2.2 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 KXX83363.1 - 0.0059 17.0 5.8 4 7.9 0.3 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KXX83363.1 - 0.051 12.8 3.3 0.16 11.2 0.1 2.7 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase HEPPP_synt_1 PF07307.11 KXX83363.1 - 0.064 12.9 0.9 0.15 11.7 0.9 1.5 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 SAM_3 PF18016.1 KXX83363.1 - 0.37 10.6 1.4 2.8 7.8 0.1 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Gag_spuma PF03276.14 KXX83364.1 - 0.034 12.6 4.7 0.037 12.5 4.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein COesterase PF00135.28 KXX83366.1 - 3.8e-77 260.3 0.0 5.1e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXX83366.1 - 0.00013 21.9 0.9 0.0016 18.3 0.9 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B PF00753.27 KXX83367.1 - 0.076 13.0 0.0 0.24 11.4 0.0 1.5 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily His_Phos_1 PF00300.22 KXX83368.1 - 6.3e-16 58.6 0.1 1.5e-14 54.1 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ABC_tran PF00005.27 KXX83369.1 - 2.6e-46 157.5 0.2 9.5e-25 87.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXX83369.1 - 1.5e-22 80.8 3.1 5.9e-06 26.3 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXX83369.1 - 1.5e-19 70.3 36.8 9.4e-15 54.6 15.4 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 KXX83369.1 - 3.6e-08 33.1 3.3 0.03 13.8 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXX83369.1 - 9.8e-08 31.6 2.9 0.0043 16.8 0.5 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF4162 PF13732.6 KXX83369.1 - 0.00013 22.6 0.1 0.57 10.9 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 KXX83369.1 - 0.00015 22.3 4.0 0.14 12.7 0.6 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXX83369.1 - 0.00062 19.7 0.3 1.3 8.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXX83369.1 - 0.00093 19.6 0.2 0.61 10.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KXX83369.1 - 0.0038 17.0 4.6 0.71 9.6 0.7 2.6 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KXX83369.1 - 0.012 15.4 0.1 5.9 6.5 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_27 PF13514.6 KXX83369.1 - 0.028 14.0 0.6 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXX83369.1 - 0.08 12.6 1.4 7.5 6.1 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KXX83369.1 - 0.12 12.6 0.9 4.6 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXX83369.1 - 0.23 11.3 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 KXX83369.1 - 0.25 11.6 0.8 34 4.8 0.2 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KXX83369.1 - 0.33 10.5 1.8 9 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KXX83369.1 - 1.3 9.0 3.5 18 5.3 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain MeaB PF03308.16 KXX83369.1 - 2.6 7.0 4.6 14 4.6 0.1 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TPR_10 PF13374.6 KXX83370.1 - 2.5e-69 227.4 0.5 1.8e-11 43.5 0.0 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXX83370.1 - 6.2e-66 218.7 7.6 1.3e-14 54.3 0.1 6.3 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXX83370.1 - 5.8e-23 79.2 2.2 0.00039 20.2 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KXX83370.1 - 4.1e-12 46.1 0.7 1.8e-07 30.9 0.2 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 KXX83370.1 - 2.2e-11 43.1 4.1 2 8.4 0.0 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXX83370.1 - 1.3e-10 40.6 5.1 1.3 9.3 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.14 KXX83370.1 - 3.2e-10 39.6 1.1 0.16 12.7 0.2 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat RelA_SpoT PF04607.17 KXX83370.1 - 5.2e-10 39.6 0.0 1.3e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TPR_19 PF14559.6 KXX83370.1 - 4.3e-09 36.8 0.2 1.3 9.5 0.0 5.9 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXX83370.1 - 7e-07 29.2 0.0 7.7 7.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 KXX83370.1 - 2.6e-05 23.5 0.1 0.00057 19.2 0.0 3.0 2 2 2 4 4 4 1 NB-ARC domain TPR_16 PF13432.6 KXX83370.1 - 3.9e-05 24.2 0.0 19 6.0 0.0 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.6 KXX83370.1 - 8.6e-05 22.8 0.0 0.0013 19.0 0.0 2.8 1 1 0 2 2 2 1 AAA domain TPR_14 PF13428.6 KXX83370.1 - 0.0006 20.4 5.3 1.3e+02 3.8 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXX83370.1 - 0.00084 19.4 2.4 59 4.2 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_16 PF13191.6 KXX83370.1 - 0.073 13.4 2.8 0.6 10.5 2.6 2.8 1 1 0 1 1 1 0 AAA ATPase domain RPN6_N PF18055.1 KXX83370.1 - 0.17 12.3 0.1 9.8 6.6 0.0 2.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Pex14_N PF04695.13 KXX83371.1 - 1.7e-37 129.5 1.5 1.7e-37 129.5 1.5 2.6 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.9 KXX83371.1 - 2e-05 25.0 0.6 2e-05 25.0 0.6 1.8 2 0 0 2 2 1 1 Zinc finger-containing protein CR6_interact PF10147.9 KXX83371.1 - 0.00068 19.4 0.5 0.001 18.8 0.5 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Golgin_A5 PF09787.9 KXX83371.1 - 0.0026 17.3 6.2 0.0037 16.8 6.2 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Prominin PF05478.11 KXX83371.1 - 0.0059 14.6 1.0 0.0076 14.3 1.0 1.1 1 0 0 1 1 1 1 Prominin DUF1043 PF06295.12 KXX83371.1 - 0.0093 16.0 1.9 0.019 15.0 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) DUF3584 PF12128.8 KXX83371.1 - 0.0096 13.5 11.1 0.013 13.1 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KXX83371.1 - 0.013 15.5 5.6 0.55 10.3 0.9 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ERM PF00769.19 KXX83371.1 - 0.014 15.2 5.2 0.022 14.6 5.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF16 PF01519.16 KXX83371.1 - 0.015 15.8 1.7 0.52 10.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 LEM PF03020.15 KXX83371.1 - 0.031 13.8 0.1 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 LEM domain DUF1978 PF09321.10 KXX83371.1 - 0.035 13.4 3.2 0.051 12.9 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) UPF0242 PF06785.11 KXX83371.1 - 0.039 14.1 3.0 0.06 13.5 3.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 5_nucleotid PF05761.14 KXX83371.1 - 0.075 11.9 2.0 0.1 11.5 2.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family tRNA-synt_His PF13393.6 KXX83371.1 - 0.076 12.3 0.9 0.31 10.3 0.6 1.9 1 1 1 2 2 2 0 Histidyl-tRNA synthetase DUF148 PF02520.17 KXX83371.1 - 0.12 12.5 3.8 0.18 11.9 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 FlgN PF05130.12 KXX83371.1 - 0.16 12.5 7.0 0.28 11.7 7.0 1.3 1 0 0 1 1 1 0 FlgN protein ADIP PF11559.8 KXX83371.1 - 0.17 11.9 8.6 0.25 11.4 7.5 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Dor1 PF04124.12 KXX83371.1 - 0.2 10.3 3.7 0.28 9.8 3.7 1.2 1 0 0 1 1 1 0 Dor1-like family TMPIT PF07851.13 KXX83371.1 - 0.29 10.3 2.1 0.48 9.6 2.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.12 KXX83371.1 - 0.33 9.4 3.9 0.44 9.0 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Plasmid_RAQPRD PF09686.10 KXX83371.1 - 0.54 10.5 4.9 2.1 8.6 3.8 2.3 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) HSP70 PF00012.20 KXX83371.1 - 0.68 8.0 4.1 0.94 7.6 4.1 1.1 1 0 0 1 1 1 0 Hsp70 protein Spc7 PF08317.11 KXX83371.1 - 0.88 8.4 7.5 1.4 7.8 7.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BST2 PF16716.5 KXX83371.1 - 0.96 10.1 4.8 0.91 10.1 3.1 1.8 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 XhlA PF10779.9 KXX83371.1 - 2 8.7 10.9 0.15 12.3 2.5 2.9 3 0 0 3 3 3 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 KXX83371.1 - 3.1 8.1 9.9 8.7 6.6 9.7 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.12 KXX83371.1 - 4 8.1 5.9 1.2 9.9 1.5 2.4 2 1 1 3 3 2 0 SlyX DUF1664 PF07889.12 KXX83371.1 - 4 7.5 5.0 4.3 7.4 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KXX83371.1 - 6.5 6.9 5.7 27 4.9 6.0 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SYCE1 PF15233.6 KXX83371.1 - 9.7 6.2 11.9 1.1 9.3 7.8 1.4 2 0 0 2 2 1 0 Synaptonemal complex central element protein 1 Abhydrolase_3 PF07859.13 KXX83372.1 - 7.3e-45 153.4 3.1 2.5e-44 151.7 3.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXX83372.1 - 0.0044 15.9 1.1 0.075 11.9 1.1 2.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Cyt-b5 PF00173.28 KXX83373.1 - 7.6e-25 86.9 0.3 9.8e-25 86.5 0.3 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.6 KXX83373.1 - 0.22 11.6 1.1 0.46 10.6 1.1 1.5 1 0 0 1 1 1 0 YqzH-like protein zf-C2H2 PF00096.26 KXX83374.1 - 9.9e-22 76.1 25.4 1.5e-05 25.1 2.0 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXX83374.1 - 6.1e-15 54.9 27.3 1.7e-06 28.2 1.2 4.7 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXX83374.1 - 1.1e-11 44.6 22.8 0.0028 18.4 1.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXX83374.1 - 4.2e-06 26.9 0.2 3.1 8.2 0.0 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KXX83374.1 - 0.0016 18.2 0.4 0.0016 18.2 0.4 3.0 3 0 0 3 3 3 1 zinc-finger C2H2-type FOXP-CC PF16159.5 KXX83374.1 - 0.039 14.6 0.9 10 6.9 0.2 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf_UBZ PF18439.1 KXX83374.1 - 0.053 13.1 3.5 0.7 9.5 0.2 2.9 4 0 0 4 4 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 KXX83374.1 - 0.063 13.4 1.2 4.7 7.3 0.2 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger IBR PF01485.21 KXX83374.1 - 0.36 11.1 5.3 11 6.3 0.7 2.7 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-MYST PF17772.1 KXX83374.1 - 0.41 10.3 2.0 18 5.0 0.0 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain zf-TRAF PF02176.18 KXX83374.1 - 0.57 10.9 8.7 1.3 9.8 0.3 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-met PF12874.7 KXX83374.1 - 1.3 9.5 14.7 6.9 7.2 0.3 4.4 6 0 0 6 6 4 0 Zinc-finger of C2H2 type zf-CRD PF17979.1 KXX83374.1 - 1.5 8.9 7.1 4.4 7.4 1.4 2.2 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions LIM PF00412.22 KXX83374.1 - 2.8 8.3 6.1 25 5.2 0.1 3.0 1 1 2 3 3 3 0 LIM domain DUF2256 PF10013.9 KXX83374.1 - 4.5 7.5 10.0 9.5 6.4 0.2 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 KXX83374.1 - 5.5 7.1 8.7 0.65 10.1 0.5 3.0 4 0 0 4 4 3 0 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KXX83374.1 - 7.5 6.8 8.7 7.9 6.7 2.3 3.0 1 1 3 4 4 4 0 Zinc ribbon domain HNH PF01844.23 KXX83374.1 - 8.1 6.7 8.4 7.9 6.7 0.1 3.7 4 0 0 4 4 4 0 HNH endonuclease HeLo PF14479.6 KXX83376.1 - 3.5e-09 36.8 0.0 4.6e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation Pox_MCEL PF03291.16 KXX83377.1 - 1e-69 235.2 0.0 5.1e-47 160.6 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KXX83377.1 - 2.1e-10 41.2 0.0 3.2e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXX83377.1 - 3e-09 37.5 0.2 0.0044 17.7 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXX83377.1 - 4.3e-06 26.6 0.0 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXX83377.1 - 7.7e-06 26.5 0.0 0.15 12.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KXX83377.1 - 8.6e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Raftlin PF15250.6 KXX83377.1 - 0.00022 20.1 0.7 0.00022 20.1 0.7 1.9 2 0 0 2 2 2 1 Raftlin NNMT_PNMT_TEMT PF01234.17 KXX83377.1 - 0.001 18.4 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family EF_assoc_2 PF08356.12 KXX83378.1 - 4.8e-35 119.4 0.0 1e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KXX83378.1 - 5.6e-32 109.2 0.2 1.5e-31 107.8 0.2 1.8 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KXX83378.1 - 1.8e-24 86.1 0.0 6.7e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXX83378.1 - 5.9e-15 55.5 0.0 5.5e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXX83378.1 - 6.1e-09 36.0 0.0 8.6e-05 22.6 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXX83378.1 - 2.2e-06 27.3 0.1 0.003 17.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXX83378.1 - 4.2e-06 26.8 0.1 0.079 12.9 0.0 3.2 2 1 0 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 KXX83378.1 - 1.5e-05 25.1 0.0 0.19 11.8 0.0 2.8 2 1 1 3 3 3 2 Dynamin family EF-hand_1 PF00036.32 KXX83378.1 - 2.2e-05 23.7 4.8 0.006 16.1 0.5 2.6 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 KXX83378.1 - 3.3e-05 24.3 0.1 0.047 14.1 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain EF-hand_7 PF13499.6 KXX83378.1 - 3.5e-05 24.2 0.3 0.11 13.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair ABC_tran PF00005.27 KXX83378.1 - 4.1e-05 24.1 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 KXX83378.1 - 4.8e-05 23.7 0.0 0.48 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain EF-hand_6 PF13405.6 KXX83378.1 - 0.00028 20.6 2.6 0.076 13.0 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain AAA_24 PF13479.6 KXX83378.1 - 0.00059 19.6 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXX83378.1 - 0.00085 18.6 0.0 0.82 8.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KXX83378.1 - 0.001 19.4 0.0 0.41 11.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase GTP_EFTU PF00009.27 KXX83378.1 - 0.0024 17.5 0.0 7 6.1 0.0 3.1 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 KXX83378.1 - 0.0045 16.9 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 KXX83378.1 - 0.0087 15.7 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXX83378.1 - 0.01 15.4 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KXX83378.1 - 0.011 15.9 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXX83378.1 - 0.012 15.8 0.0 4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 KXX83378.1 - 0.014 15.2 2.5 3.7 7.5 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Septin PF00735.18 KXX83378.1 - 0.015 14.6 0.0 0.56 9.4 0.0 2.2 2 0 0 2 2 2 0 Septin NACHT PF05729.12 KXX83378.1 - 0.019 14.9 0.0 3.2 7.7 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_23 PF13476.6 KXX83378.1 - 0.025 15.1 0.1 2 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 KXX83378.1 - 0.026 13.6 0.1 2 7.4 0.0 2.5 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) EF-hand_5 PF13202.6 KXX83378.1 - 0.048 13.2 6.4 0.32 10.6 1.7 2.7 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 KXX83378.1 - 0.064 13.6 0.1 9.9 6.5 0.0 3.0 2 1 1 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region Zeta_toxin PF06414.12 KXX83378.1 - 0.068 12.4 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 KXX83378.1 - 0.097 12.1 0.0 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain EF-hand_10 PF14788.6 KXX83378.1 - 0.1 12.5 0.3 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 EF hand AAA_18 PF13238.6 KXX83378.1 - 0.11 13.0 0.0 2.1 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXX83378.1 - 0.14 12.6 0.1 7 7.1 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.16 KXX83378.1 - 0.15 11.3 0.4 2.4 7.4 0.3 2.4 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 KXX83378.1 - 0.16 11.6 0.2 12 5.4 0.0 3.5 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KXX83378.1 - 0.18 11.6 0.0 9.3 5.9 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein MCM PF00493.23 KXX83378.1 - 0.19 10.8 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain WD40 PF00400.32 KXX83379.1 - 6.6e-12 45.8 20.7 7.9e-05 23.4 0.4 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX83379.1 - 8.7e-08 32.4 0.0 5e-05 23.5 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXX83379.1 - 0.00054 19.8 0.5 1.3 9.0 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KXX83379.1 - 0.031 14.2 0.0 0.08 12.8 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXX83379.1 - 0.045 12.3 0.0 0.076 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain IKI3 PF04762.12 KXX83379.1 - 0.063 11.3 0.0 0.085 10.8 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Arrestin_C PF02752.22 KXX83380.1 - 8.1e-20 71.6 0.0 1.5e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXX83380.1 - 9.2e-08 32.3 0.0 0.00061 19.9 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KXX83380.1 - 0.0025 17.6 0.0 0.0063 16.2 0.0 1.7 1 0 0 1 1 1 1 Arrestin_N terminal like F-actin_cap_A PF01267.17 KXX83381.1 - 1.9e-87 293.1 0.0 2.1e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ACAS_N PF16177.5 KXX83381.1 - 0.037 13.9 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus TFA2_Winged_2 PF18121.1 KXX83382.1 - 1.1e-23 82.6 0.1 2.4e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KXX83382.1 - 2.1e-08 34.3 0.0 5.8e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 TFIIE beta subunit core domain Dermcidin PF15291.6 KXX83382.1 - 0.03 14.9 0.3 0.09 13.3 0.3 1.8 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Speriolin_N PF15058.6 KXX83382.1 - 0.082 13.0 3.2 0.14 12.2 3.2 1.3 1 0 0 1 1 1 0 Speriolin N terminus FAD_binding_4 PF01565.23 KXX83383.1 - 2.9e-08 33.6 0.0 7.6e-06 25.7 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Na_Ca_ex PF01699.24 KXX83384.1 - 3.6e-42 143.9 38.8 1.6e-21 76.8 16.5 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF1201 PF06716.11 KXX83384.1 - 0.03 14.3 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) SLATT_5 PF18160.1 KXX83384.1 - 1.3 8.3 3.1 1.1 8.6 0.1 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 CDO_I PF05995.12 KXX83385.1 - 3.3e-43 146.9 0.0 4.3e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXX83385.1 - 0.012 15.1 0.1 0.017 14.6 0.1 1.4 1 1 0 1 1 1 0 PCO_ADO DEC1 PF15859.5 KXX83385.1 - 0.086 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family Git3 PF11710.8 KXX83386.1 - 2.3e-17 63.4 7.0 5.1e-17 62.3 7.0 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KXX83386.1 - 6e-09 35.6 0.0 7.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KXX83386.1 - 0.04 13.1 8.0 0.08 12.1 8.0 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor 7TM_GPCR_Srz PF10325.9 KXX83386.1 - 0.11 11.8 5.5 0.38 10.1 5.5 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz CBFD_NFYB_HMF PF00808.23 KXX83387.1 - 2.4e-11 43.7 0.1 3.9e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.20 KXX83388.1 - 6.8e-88 295.3 30.6 6.8e-88 295.3 30.6 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXX83388.1 - 4.8e-12 46.1 0.6 4.2e-05 23.9 0.1 2.6 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.25 KXX83389.1 - 1.4e-22 80.4 0.0 2.1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KXX83389.1 - 1.6e-11 43.4 1.7 0.011 16.0 0.2 6.3 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 KXX83389.1 - 7.9e-10 39.2 14.1 1.2e-06 29.2 0.1 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KXX83389.1 - 1e-05 25.9 1.3 1.2 9.6 0.3 4.1 2 1 1 3 3 3 2 HEAT repeats Pkinase_Tyr PF07714.17 KXX83389.1 - 2.2e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 KXX83389.1 - 9.8e-05 22.4 0.1 7.1 6.6 0.0 3.9 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXX83389.1 - 0.00015 22.2 0.6 0.013 15.9 0.2 3.0 2 0 0 2 2 2 1 HEAT-like repeat Kinase-like PF14531.6 KXX83389.1 - 0.01 15.2 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like LRR_9 PF14580.6 KXX83390.1 - 4.4e-54 182.6 0.1 7.1e-54 181.9 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KXX83390.1 - 2.3e-08 34.2 6.1 3.7e-05 24.0 0.4 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXX83390.1 - 1.4e-07 31.1 2.2 1.5e-07 31.1 0.4 2.1 2 0 0 2 2 2 1 Leucine rich repeat DUF4349 PF14257.6 KXX83390.1 - 0.00052 19.5 2.7 0.00096 18.6 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_6 PF13516.6 KXX83390.1 - 0.083 13.0 1.8 51 4.3 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeat PspB PF06667.12 KXX83390.1 - 0.21 11.7 3.6 0.75 9.9 1.7 2.6 3 0 0 3 3 3 0 Phage shock protein B DUF3112 PF11309.8 KXX83391.1 - 0.00015 21.3 1.4 0.034 13.6 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) DUF2178 PF09946.9 KXX83391.1 - 0.48 10.6 3.7 0.36 11.0 0.3 2.4 1 1 2 3 3 3 0 Predicted membrane protein (DUF2178) SH3_9 PF14604.6 KXX83392.1 - 6.8e-06 25.8 0.2 1.5e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXX83392.1 - 0.00012 21.6 0.4 0.00023 20.7 0.4 1.5 1 0 0 1 1 1 1 SH3 domain DUF4690 PF15756.5 KXX83392.1 - 0.25 12.0 2.2 0.31 11.7 0.3 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage ACT PF01842.25 KXX83393.1 - 0.0071 16.1 0.1 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 ACT domain HLH PF00010.26 KXX83393.1 - 0.28 11.2 2.0 0.84 9.7 0.7 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain zf-C2H2 PF00096.26 KXX83394.1 - 0.00023 21.4 9.7 0.026 15.0 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXX83394.1 - 0.016 16.0 9.8 0.2 12.6 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger RRM_1 PF00076.22 KXX83396.1 - 2.8e-31 107.2 0.2 7.2e-15 54.6 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXX83396.1 - 6e-05 23.1 0.0 0.038 14.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KXX83396.1 - 0.0015 18.1 0.0 1.4 8.6 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCC1 PF15506.6 KXX83396.1 - 0.019 15.1 2.9 0.019 15.1 2.9 2.9 2 1 0 2 2 2 0 OCC1 family PHM7_cyt PF14703.6 KXX83396.1 - 0.03 14.5 0.1 9 6.5 0.0 3.4 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DbpA PF03880.15 KXX83396.1 - 0.037 14.0 0.1 9.5 6.3 0.1 3.1 3 0 0 3 3 3 0 DbpA RNA binding domain DUF4783 PF16022.5 KXX83396.1 - 0.05 13.8 0.0 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) Pns11_12 PF17464.2 KXX83396.1 - 1.6 8.4 7.3 1.5 8.5 5.8 1.7 2 0 0 2 2 2 0 Non-structural protein 11 and 12 Flavodoxin_1 PF00258.25 KXX83397.1 - 1.2e-29 103.4 0.0 1.8e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KXX83397.1 - 3.3e-25 89.0 0.0 5.6e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KXX83397.1 - 2.1e-09 38.0 0.0 1.9e-07 31.7 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 KXX83397.1 - 0.041 13.6 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Flavodoxin domain ETF PF01012.21 KXX83398.1 - 3e-45 154.3 0.5 3.6e-45 154.1 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.18 KXX83399.1 - 8.9e-32 109.6 0.0 1.6e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ATP_bind_1 PF03029.17 KXX83400.1 - 8.8e-78 261.4 0.0 1.2e-77 260.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KXX83400.1 - 0.0011 18.1 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KXX83400.1 - 0.015 15.2 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXX83400.1 - 0.018 14.3 0.0 0.045 13.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 KXX83400.1 - 0.042 12.8 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 KXX83400.1 - 0.045 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GIT_SHD PF08518.11 KXX83400.1 - 0.061 13.0 1.2 0.17 11.5 1.2 1.8 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT GTP_EFTU PF00009.27 KXX83400.1 - 0.11 12.0 0.1 8.9 5.8 0.0 2.7 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXX83400.1 - 0.2 11.8 0.0 2.8 8.0 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KXX83400.1 - 0.51 10.8 4.4 1.1 9.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain RNase_P_Rpp14 PF01900.19 KXX83401.1 - 9e-37 125.4 0.0 1.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family WD40 PF00400.32 KXX83403.1 - 5.8e-31 106.1 5.9 3.3e-06 27.7 0.7 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX83403.1 - 3.9e-08 33.5 0.0 0.12 12.7 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXX83403.1 - 5.7e-06 25.3 6.4 0.37 9.4 0.0 5.3 5 1 1 6 6 6 4 Nucleoporin Nup120/160 DUF5046 PF16465.5 KXX83403.1 - 0.027 13.9 0.1 0.27 10.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5046) BRO1 PF03097.18 KXX83403.1 - 0.082 11.7 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 BRO1-like domain K_channel_TID PF07941.11 KXX83403.1 - 0.17 12.4 2.5 0.46 11.0 2.5 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.32 KXX83405.1 - 2.8e-16 59.6 0.0 0.0096 16.8 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX83405.1 - 0.00024 21.3 0.0 6.2 7.2 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GATA PF00320.27 KXX83407.1 - 6.5e-16 57.6 2.8 1.5e-15 56.5 2.8 1.6 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KXX83407.1 - 0.014 15.5 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 KXX83407.1 - 0.024 14.7 1.3 0.037 14.1 0.7 1.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RRN7 PF11781.8 KXX83407.1 - 0.027 14.2 2.2 0.06 13.0 2.2 1.5 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 KXX83407.1 - 0.045 13.3 0.3 0.086 12.4 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding SPX PF03105.19 KXX83407.1 - 1.1 9.1 8.7 2.2 8.1 8.7 1.5 1 0 0 1 1 1 0 SPX domain Ribosomal_L32p PF01783.23 KXX83407.1 - 7.3 6.9 6.7 6.8 7.0 2.9 3.0 2 1 0 2 2 2 0 Ribosomal L32p protein family COPI_assoc PF08507.10 KXX83408.1 - 7.6e-34 116.6 5.6 8.1e-34 116.5 5.6 1.0 1 0 0 1 1 1 1 COPI associated protein TMEM72 PF16054.5 KXX83408.1 - 0.16 11.6 4.1 1.4 8.6 1.3 2.0 2 0 0 2 2 2 0 Transmembrane protein family 72 MFS_MOT1 PF16983.5 KXX83408.1 - 1.8 9.0 7.8 25 5.3 7.8 2.2 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily BCIP PF13862.6 KXX83409.1 - 1.2e-65 221.2 0.1 1.6e-65 220.7 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein RTT107_BRCT_5 PF16770.5 KXX83410.1 - 1.5e-33 114.6 0.0 4.4e-31 106.7 0.0 3.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KXX83410.1 - 1.2e-32 111.7 1.9 7.9e-20 70.6 0.2 5.0 6 0 0 6 6 6 3 twin BRCT domain BRCT_2 PF16589.5 KXX83410.1 - 1.3e-27 96.0 0.0 3.4e-06 27.4 0.0 5.5 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXX83410.1 - 2.1e-26 92.1 0.0 1.9e-07 31.3 0.0 5.6 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXX83410.1 - 3.9e-11 43.1 0.3 0.02 15.2 0.0 3.9 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KXX83410.1 - 0.0019 18.2 0.1 1.9 8.6 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Ndc80_HEC PF03801.13 KXX83412.1 - 2.3e-42 144.2 0.3 4.9e-26 91.2 0.1 2.6 1 1 1 2 2 2 2 HEC/Ndc80p family Spc7 PF08317.11 KXX83412.1 - 0.00057 18.9 44.4 0.0014 17.6 13.1 2.9 3 0 0 3 3 3 2 Spc7 kinetochore protein DHR10 PF18595.1 KXX83412.1 - 0.00073 19.6 18.6 0.00073 19.6 18.6 3.9 2 2 2 4 4 4 1 Designed helical repeat protein 10 domain DUF4391 PF14335.6 KXX83412.1 - 0.013 15.3 6.6 0.013 15.3 6.6 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4391) DUF1664 PF07889.12 KXX83412.1 - 0.037 14.1 0.8 0.037 14.1 0.8 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 KXX83412.1 - 0.1 12.9 50.3 0.16 12.2 6.6 5.4 3 1 1 5 5 5 0 ABC transporter C-terminal domain WASH_WAHD PF11945.8 KXX83412.1 - 0.31 10.5 10.0 0.059 12.9 4.6 2.2 2 0 0 2 2 2 0 WAHD domain of WASH complex APG6_N PF17675.1 KXX83412.1 - 0.62 10.6 56.0 0.73 10.4 3.7 4.8 2 1 1 4 4 4 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KXX83412.1 - 2.3 8.7 10.6 12 6.4 2.2 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KXX83412.1 - 4.1 6.7 31.8 0.64 9.3 10.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Mito_fiss_reg PF05308.11 KXX83412.1 - 6.5 6.8 13.7 0.19 11.8 5.1 2.6 2 1 0 2 2 2 0 Mitochondrial fission regulator ASPRs PF17641.2 KXX83412.1 - 7.3 6.9 8.0 9.2 6.6 2.2 2.8 2 0 0 2 2 2 0 Ancylostoma-associated secreted protein related DUF16 PF01519.16 KXX83412.1 - 9.7 6.7 26.6 0.27 11.8 7.9 3.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 zf-Nse PF11789.8 KXX83413.1 - 3.8e-19 68.3 2.0 7e-19 67.4 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXX83413.1 - 0.00027 20.9 0.3 0.00049 20.1 0.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 KXX83413.1 - 0.00094 18.9 0.9 0.0016 18.2 0.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 KXX83413.1 - 0.0015 18.3 1.4 0.0023 17.7 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Use1 PF09753.9 KXX83413.1 - 0.025 14.3 0.4 0.052 13.3 0.4 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 zf-ANAPC11 PF12861.7 KXX83413.1 - 0.053 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXX83413.1 - 0.072 13.4 0.9 0.12 12.8 0.9 1.4 1 0 0 1 1 1 0 Ring finger domain U-box PF04564.15 KXX83413.1 - 0.084 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 U-box domain Zn-ribbon_8 PF09723.10 KXX83413.1 - 0.16 12.2 0.2 0.34 11.1 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4 PF00097.25 KXX83413.1 - 0.27 11.1 2.3 0.45 10.4 2.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBB PF01749.20 KXX83413.1 - 1 9.8 9.5 5.4 7.5 0.0 3.8 3 1 0 3 3 3 0 Importin beta binding domain Cwf_Cwc_15 PF04889.12 KXX83413.1 - 7.1 6.3 12.5 3.7 7.2 1.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cupin_2 PF07883.11 KXX83414.1 - 1.7e-14 53.3 0.1 2.4e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXX83414.1 - 6.9e-09 35.5 0.0 8.5e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KXX83414.1 - 9.8e-07 28.8 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KXX83414.1 - 0.00046 19.8 0.0 0.00084 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXX83414.1 - 0.0021 17.8 0.1 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 KXX83414.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 KXX83414.1 - 0.032 14.4 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like SUN PF03856.13 KXX83415.1 - 2.8e-76 256.2 6.5 3.8e-76 255.8 6.5 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Clr2 PF10383.9 KXX83416.1 - 3.7e-26 92.7 0.0 7e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KXX83416.1 - 1.5e-15 57.8 0.3 2.7e-15 56.9 0.3 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Thiolase_N PF00108.23 KXX83417.1 - 1.1e-85 287.1 0.4 2e-85 286.3 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXX83417.1 - 8.9e-38 128.7 1.9 1.7e-37 127.8 1.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXX83417.1 - 5.7e-05 22.8 0.3 0.00017 21.3 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXX83417.1 - 0.82 9.6 3.5 13 5.8 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MutL_C PF08676.11 KXX83418.1 - 3.5e-23 82.0 0.4 1.4e-22 80.0 0.1 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KXX83418.1 - 3.3e-17 62.2 0.0 8.2e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXX83418.1 - 1.7e-10 40.9 4.2 2.6e-10 40.3 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXX83418.1 - 2.1e-05 25.0 0.1 9.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.13 KXX83419.1 - 5.7e-93 310.9 0.0 8.3e-93 310.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXX83419.1 - 0.00025 21.7 0.3 0.00056 20.6 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXX83419.1 - 0.0027 17.4 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXX83419.1 - 0.0048 16.2 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KXX83419.1 - 0.02 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 KXX83419.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KXX83419.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase adh_short PF00106.25 KXX83420.1 - 1.1e-31 109.8 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXX83420.1 - 1.3e-19 70.7 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXX83420.1 - 4.7e-06 26.6 0.0 6.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXX83420.1 - 0.072 12.4 0.0 0.63 9.4 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXX83420.1 - 0.21 11.0 0.0 1.2 8.6 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KXX83422.1 - 1.4e-05 24.6 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXX83422.1 - 0.0062 15.9 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TerB PF05099.13 KXX83423.1 - 0.024 14.6 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB Kinesin PF00225.23 KXX83425.1 - 2.6e-113 378.3 0.5 7e-113 376.9 0.5 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXX83425.1 - 1.4e-26 93.3 1.7 2.4e-26 92.4 0.1 2.3 2 0 0 2 2 2 1 Microtubule binding UQ_con PF00179.26 KXX83426.1 - 4.8e-52 175.3 0.1 5.4e-52 175.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXX83426.1 - 0.00058 19.6 0.0 0.00064 19.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXX83426.1 - 0.04 14.2 0.0 0.053 13.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain Aminotran_1_2 PF00155.21 KXX83429.1 - 1.2e-37 130.0 0.0 1.6e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Spherulin4 PF12138.8 KXX83429.1 - 0.2 11.3 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Spherulation-specific family 4 RPN7 PF10602.9 KXX83430.1 - 4.4e-57 192.6 1.6 5.6e-57 192.2 0.4 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KXX83430.1 - 5e-14 52.7 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain LigB PF02900.18 KXX83430.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Med13_C PF06333.12 KXX83431.1 - 1.9e-88 296.9 3.0 1.9e-88 296.9 3.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KXX83431.1 - 1.7e-25 90.1 0.0 3.2e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KXX83431.1 - 3.6e-12 46.6 5.3 7.7e-06 25.9 0.0 3.3 3 1 0 4 4 4 2 MID domain of medPIWI NUC153 PF08159.12 KXX83432.1 - 3e-12 46.1 0.7 6e-12 45.2 0.7 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KXX83432.1 - 0.0021 18.8 0.0 13 6.8 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXX83432.1 - 0.0087 16.3 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain CTP_transf_like PF01467.26 KXX83433.1 - 2.8e-20 73.0 0.0 4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Putative_PNPOx PF01243.20 KXX83434.1 - 1.5e-07 31.5 0.0 1.1e-05 25.5 0.0 2.7 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase Kre28 PF17097.5 KXX83435.1 - 0.12 11.3 2.3 0.2 10.6 2.3 1.2 1 0 0 1 1 1 0 Spindle pole body component Chromo_shadow PF01393.19 KXX83436.1 - 8.2e-21 73.9 2.3 1.3e-18 66.8 0.2 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KXX83436.1 - 2.4e-14 53.0 0.9 2.4e-14 53.0 0.9 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain BUD22 PF09073.10 KXX83436.1 - 0.015 14.7 17.8 0.02 14.3 17.8 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KXX83436.1 - 2.4 6.1 19.3 3.2 5.7 19.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi FYDLN_acid PF09538.10 KXX83436.1 - 4.2 8.1 16.9 0.84 10.3 11.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RRN3 PF05327.11 KXX83436.1 - 8.7 4.8 7.9 11 4.5 7.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MFS_1 PF07690.16 KXX83437.1 - 2e-17 63.2 34.1 6.1e-15 55.0 9.2 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.13 KXX83437.1 - 1.9e-09 37.4 3.1 5e-09 36.0 3.1 1.7 1 0 0 1 1 1 1 Nodulin-like LCM PF04072.14 KXX83438.1 - 2e-24 86.5 0.0 4.6e-24 85.4 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase MCM PF00493.23 KXX83439.1 - 7.3e-98 326.1 0.2 1.2e-97 325.4 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXX83439.1 - 1.5e-31 108.9 0.0 2.7e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXX83439.1 - 3.1e-25 88.4 1.7 6.8e-25 87.3 1.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXX83439.1 - 2.2e-11 44.2 0.0 7e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXX83439.1 - 4.6e-07 29.4 0.0 5.3e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXX83439.1 - 0.0023 17.8 0.0 0.0061 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXX83439.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Apt1 PF10351.9 KXX83439.1 - 0.12 11.2 7.3 0.18 10.6 7.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAP_N PF01213.19 KXX83440.1 - 2.6e-115 385.3 0.2 4e-115 384.7 0.2 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KXX83440.1 - 1.7e-54 183.7 1.5 2.3e-54 183.3 1.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DUF2433 PF10360.9 KXX83441.1 - 2.5e-50 169.7 0.0 3.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KXX83441.1 - 0.00074 20.1 0.0 0.0015 19.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXX83441.1 - 0.0043 17.3 0.0 0.019 15.2 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CCDC53 PF10152.9 KXX83441.1 - 0.12 12.8 2.4 0.54 10.7 2.4 2.0 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Fungal_trans PF04082.18 KXX83442.1 - 1.6e-37 129.0 0.0 3.1e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dna2 PF08696.11 KXX83442.1 - 0.0029 17.4 0.4 0.0052 16.6 0.4 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 E1_dh PF00676.20 KXX83443.1 - 4.2e-89 298.4 0.0 5.5e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KXX83443.1 - 0.0022 17.8 0.0 0.022 14.6 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SGS PF05002.15 KXX83443.1 - 0.32 11.1 1.9 1.1 9.4 0.5 2.2 2 0 0 2 2 2 0 SGS domain Ubie_methyltran PF01209.18 KXX83444.1 - 5.2e-69 232.1 0.0 6.5e-42 143.5 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXX83444.1 - 1.2e-11 45.2 0.0 2e-05 25.2 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXX83444.1 - 2.4e-10 40.9 0.0 1.7e-05 25.4 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXX83444.1 - 1.9e-08 34.9 0.0 4.6e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXX83444.1 - 1.6e-07 31.3 0.0 6.5e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXX83444.1 - 9.4e-06 25.6 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KXX83444.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 KXX83444.1 - 0.16 11.5 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Glyco_hydro_125 PF06824.11 KXX83445.1 - 5.9e-179 595.3 0.0 6.8e-179 595.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CTD_bind PF04818.13 KXX83445.1 - 0.21 12.5 0.0 3.7 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II-binding domain. FAA_hydrolase PF01557.18 KXX83446.1 - 6.9e-54 182.8 0.0 9.4e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PigN PF04987.14 KXX83447.1 - 5e-166 553.1 28.0 6.7e-166 552.7 28.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KXX83447.1 - 4.9e-11 42.8 2.0 3.9e-09 36.5 1.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXX83447.1 - 5e-07 29.4 0.1 8.4e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase CDC27 PF09507.10 KXX83448.1 - 1.2e-68 232.5 35.3 6e-68 230.2 35.3 2.3 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 K_channel_TID PF07941.11 KXX83448.1 - 0.065 13.7 2.2 0.16 12.5 2.2 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CDC45 PF02724.14 KXX83448.1 - 1.7 6.8 12.3 2.2 6.5 12.3 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KXX83448.1 - 1.9 7.7 10.6 3.3 7.0 10.6 1.4 1 0 0 1 1 1 0 NOA36 protein Exo70 PF03081.15 KXX83449.1 - 1.5e-91 307.3 0.0 5.7e-91 305.4 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit CSN8_PSD8_EIF3K PF10075.9 KXX83449.1 - 0.061 13.3 0.0 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family eIF-3c_N PF05470.12 KXX83449.1 - 0.067 11.5 0.0 0.13 10.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Apolipoprotein PF01442.18 KXX83449.1 - 0.39 10.6 5.9 0.41 10.5 0.1 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2203 PF09969.9 KXX83449.1 - 0.4 11.4 3.0 0.75 10.5 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Baculo_PEP_C PF04513.12 KXX83449.1 - 2.9 7.9 7.1 48 4.0 0.1 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aminotran_3 PF00202.21 KXX83450.1 - 3.8e-86 289.3 0.0 4.6e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXX83450.1 - 8.1e-06 25.2 0.0 2.3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II PNP_UDP_1 PF01048.20 KXX83451.1 - 5e-41 140.5 1.7 5.8e-41 140.3 1.7 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Atx10homo_assoc PF09759.9 KXX83452.1 - 9.8e-10 38.4 0.0 2.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain KH_1 PF00013.29 KXX83453.1 - 2.9e-92 302.5 35.1 1.4e-12 47.3 0.2 12.4 12 1 0 12 12 12 9 KH domain SLS PF14611.6 KXX83453.1 - 4.2e-13 49.6 10.6 0.0078 16.1 0.0 7.3 3 1 4 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KXX83453.1 - 5.9e-11 42.0 30.1 0.00041 20.1 0.1 8.4 8 2 1 9 9 9 4 KH domain KH_4 PF13083.6 KXX83453.1 - 0.0017 18.2 6.6 0.23 11.4 0.1 5.7 6 0 0 6 6 6 1 KH domain Acylphosphatase PF00708.18 KXX83453.1 - 0.21 12.0 11.0 8.2 6.9 0.2 5.1 6 0 0 6 6 6 0 Acylphosphatase NIL PF09383.10 KXX83453.1 - 0.42 10.5 2.9 41 4.1 0.0 4.3 4 0 0 4 4 4 0 NIL domain DUF5300 PF17224.3 KXX83453.1 - 9 6.6 10.5 31 4.9 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF5300) Pkinase PF00069.25 KXX83454.1 - 1e-71 241.4 0.0 1.5e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXX83454.1 - 8.9e-46 156.3 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXX83454.1 - 2.3e-18 66.3 0.0 6.7e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KXX83454.1 - 1.1e-07 31.5 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXX83454.1 - 1e-06 27.9 0.8 2e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXX83454.1 - 0.012 15.0 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXX83454.1 - 0.017 15.1 0.4 0.18 11.7 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXX83454.1 - 0.032 13.2 0.0 0.032 13.2 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KXX83454.1 - 0.14 11.8 0.7 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 adh_short_C2 PF13561.6 KXX83455.1 - 9.8e-62 208.6 1.1 1.3e-61 208.2 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXX83455.1 - 1.6e-50 171.3 0.9 2.2e-50 170.9 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXX83455.1 - 3.1e-10 40.3 0.3 4.7e-10 39.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXX83455.1 - 0.00016 21.2 0.2 0.00049 19.6 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXX83455.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXX83455.1 - 0.03 13.7 0.1 0.062 12.7 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase SelR PF01641.18 KXX83456.1 - 3e-39 133.8 0.5 1.1e-38 132.1 0.5 1.7 1 1 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KXX83456.1 - 0.037 14.2 0.1 0.069 13.4 0.1 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 KXX83456.1 - 0.038 14.0 1.1 2.4 8.3 0.0 2.3 2 1 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 KXX83456.1 - 6.5 6.5 7.8 11 5.7 0.1 3.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Carn_acyltransf PF00755.20 KXX83457.1 - 1.7e-199 664.3 0.0 2.4e-199 663.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SWIRM PF04433.17 KXX83458.1 - 3.4e-32 110.6 0.1 7.9e-32 109.5 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KXX83458.1 - 8.1e-32 109.0 4.7 8.1e-32 109.0 4.7 1.7 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KXX83458.1 - 3.7e-10 39.8 0.1 7.6e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXX83458.1 - 0.00018 21.7 0.4 0.00038 20.6 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KXX83458.1 - 0.048 13.9 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 KXX83458.1 - 0.076 12.9 0.5 0.51 10.3 0.0 2.3 2 0 0 2 2 2 0 Myb DNA-binding like DUF3439 PF11921.8 KXX83458.1 - 0.12 12.3 5.0 0.28 11.2 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 KXX83458.1 - 0.38 8.9 7.3 0.54 8.4 7.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ZZ PF00569.17 KXX83458.1 - 0.67 9.8 2.9 1.4 8.8 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type ETF PF01012.21 KXX83459.1 - 7.9e-44 149.7 4.0 1.3e-43 149.0 4.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KXX83459.1 - 3.2e-34 116.8 0.5 7.4e-34 115.6 0.5 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.14 KXX83460.1 - 3.6e-07 29.7 0.1 4e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX83460.1 - 0.0022 18.2 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXX83460.1 - 0.097 11.3 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXX83460.1 - 0.25 10.6 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 KXX83462.1 - 6e-86 288.7 0.0 7.8e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3295 PF11702.8 KXX83463.1 - 1.5e-166 555.6 33.4 1.9e-166 555.3 33.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KXX83463.1 - 1.1e-12 47.6 3.1 2.1e-12 46.6 3.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RTA1 PF04479.13 KXX83464.1 - 1.1e-53 182.0 6.3 1.1e-53 182.0 6.3 1.6 1 1 1 2 2 2 1 RTA1 like protein DUF4131 PF13567.6 KXX83464.1 - 6.7 6.3 21.6 0.85 9.2 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) VHS PF00790.19 KXX83465.1 - 7.5e-43 145.8 2.2 6.1e-42 142.8 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KXX83465.1 - 4.3e-15 55.6 3.9 9.6e-15 54.5 3.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KXX83465.1 - 8.1e-07 28.5 12.4 0.0025 17.6 1.5 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 KXX83465.1 - 7.1e-05 23.0 0.0 0.00027 21.2 0.0 2.1 1 0 0 1 1 1 1 GAT domain FYVE_2 PF02318.16 KXX83465.1 - 0.12 12.6 3.5 0.094 12.9 1.6 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger Fer4_2 PF12797.7 KXX83465.1 - 1.1 9.5 7.6 2.4 8.4 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain EPL1 PF10513.9 KXX83465.1 - 1.2 9.5 11.3 8.1 6.8 4.2 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like BAF1_ABF1 PF04684.13 KXX83465.1 - 10 5.1 14.9 0.97 8.4 7.3 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Dioxygenase_C PF00775.21 KXX83466.1 - 3e-42 144.1 0.0 4e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXX83466.1 - 1.8e-22 79.0 0.1 3.4e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXX83466.1 - 0.003 17.8 0.0 0.0099 16.1 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Complex1_30kDa PF00329.19 KXX83467.1 - 1.3e-44 151.7 0.0 2e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit GMC_oxred_N PF00732.19 KXX83468.1 - 1.1e-64 218.7 0.1 1.7e-64 218.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXX83468.1 - 1.3e-35 123.0 0.0 2.2e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXX83468.1 - 1e-06 28.2 0.0 0.0088 15.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 KXX83468.1 - 0.0011 19.5 0.4 2.6 8.7 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXX83468.1 - 0.0019 17.8 0.2 0.17 11.4 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXX83468.1 - 0.0025 17.1 0.2 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXX83468.1 - 0.0054 16.9 0.2 0.018 15.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXX83468.1 - 0.023 13.8 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KXX83468.1 - 0.036 13.3 0.4 0.075 12.3 0.0 1.6 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KXX83468.1 - 0.16 12.3 0.6 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KXX83468.1 - 0.19 11.0 0.4 9.1 5.4 0.1 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KXX83468.1 - 0.21 10.1 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Tht1 PF04163.12 KXX83470.1 - 2.6e-06 26.5 0.3 7.3e-06 25.0 0.2 1.6 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF3829 PF12889.7 KXX83470.1 - 0.0042 16.6 0.6 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3829) Fzo_mitofusin PF04799.13 KXX83470.1 - 0.0069 16.0 0.8 0.0069 16.0 0.8 2.4 1 1 1 2 2 2 1 fzo-like conserved region Fmp27_WPPW PF10359.9 KXX83470.1 - 0.034 13.0 12.0 0.3 9.9 3.0 2.1 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain NiFe_hyd_3_EhaA PF17367.2 KXX83470.1 - 0.098 12.8 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A NPV_P10 PF05531.12 KXX83470.1 - 0.16 12.4 7.9 0.38 11.3 0.4 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 KXX83470.1 - 0.19 11.9 1.0 1.1 9.5 0.2 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Chlorosome_CsmC PF11098.8 KXX83470.1 - 0.21 11.6 1.9 0.47 10.4 1.9 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C DASH_Spc19 PF08287.11 KXX83470.1 - 0.28 11.1 11.6 1.6 8.6 4.7 2.3 2 0 0 2 2 2 0 Spc19 Fib_alpha PF08702.10 KXX83470.1 - 0.69 10.1 11.3 19 5.4 0.7 3.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Nup54 PF13874.6 KXX83470.1 - 0.71 10.0 15.1 1.4 9.0 2.3 3.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 KXX83470.1 - 0.75 8.6 13.1 0.24 10.3 7.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1451 PF07295.11 KXX83470.1 - 0.76 9.8 10.8 0.96 9.5 1.0 2.6 1 1 1 2 2 2 0 Zinc-ribbon containing domain Tropomyosin_1 PF12718.7 KXX83470.1 - 0.81 9.8 11.7 0.42 10.8 5.3 2.2 1 1 0 2 2 2 0 Tropomyosin like DUF3450 PF11932.8 KXX83470.1 - 0.91 8.8 12.7 0.69 9.2 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DegS PF05384.11 KXX83470.1 - 0.93 9.0 8.4 0.15 11.5 1.9 2.5 2 1 1 3 3 3 0 Sensor protein DegS ERM PF00769.19 KXX83470.1 - 1.6 8.5 10.3 0.35 10.7 1.3 2.2 1 1 0 2 2 2 0 Ezrin/radixin/moesin family BRE1 PF08647.11 KXX83470.1 - 1.7 8.8 8.8 1.2 9.3 1.0 2.7 2 2 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4570 PF15134.6 KXX83470.1 - 3 7.9 7.0 1.3 9.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) DUF848 PF05852.11 KXX83470.1 - 4.6 7.4 10.2 0.14 12.3 2.2 2.0 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Atg14 PF10186.9 KXX83470.1 - 4.8 6.2 11.7 1.3 8.1 7.2 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HSCB_C PF07743.13 KXX83470.1 - 4.8 7.7 9.4 2.2 8.8 0.6 3.0 3 1 0 3 3 2 0 HSCB C-terminal oligomerisation domain DUF948 PF06103.11 KXX83470.1 - 5.4 7.4 8.6 8.1 6.8 1.6 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 KXX83470.1 - 5.8 6.2 10.4 2.3 7.5 6.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KXX83470.1 - 7.7 6.7 12.2 15 5.7 3.2 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 KXX83470.1 - 7.9 6.0 14.2 61 3.0 14.2 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KXX83470.1 - 8.7 6.4 8.7 2.7 8.1 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 KXX83470.1 - 9.5 4.0 6.4 4.7 5.0 1.3 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Lactonase PF10282.9 KXX83471.1 - 1.6e-14 53.9 0.0 2.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Ion_trans_2 PF07885.16 KXX83472.1 - 6e-34 115.9 27.6 5e-19 68.1 2.0 3.1 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KXX83472.1 - 0.0021 17.4 17.6 0.11 11.7 0.2 2.7 2 1 0 2 2 2 2 Ion transport protein Inositol_P PF00459.25 KXX83474.1 - 8.3e-51 173.1 0.9 1.6e-50 172.1 0.9 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 KXX83475.1 - 2.1e-20 73.2 0.0 8.1e-09 36.0 0.0 2.8 2 1 1 3 3 3 2 Ribosomal protein L6 DUF2781 PF10914.8 KXX83475.1 - 0.00015 22.2 0.0 0.00031 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Clr5 PF14420.6 KXX83476.1 - 1.8e-16 60.1 3.6 2.3e-16 59.7 3.6 1.2 1 0 0 1 1 1 1 Clr5 domain SAM_LFY PF01698.16 KXX83476.1 - 0.038 13.9 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain DUF1560 PF07597.11 KXX83476.1 - 0.047 13.7 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) Apolipoprotein PF01442.18 KXX83477.1 - 0.0065 16.4 0.5 0.0065 16.4 0.5 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain PH PF00169.29 KXX83477.1 - 0.018 15.5 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 PH domain DUF2891 PF11199.8 KXX83477.1 - 0.051 12.5 0.1 0.098 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Thiamine_BP PF01910.17 KXX83477.1 - 0.072 13.0 0.2 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Thiamine-binding protein TssC PF17541.2 KXX83477.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Phage_holin_2_4 PF16082.5 KXX83478.1 - 0.01 15.6 1.3 0.013 15.2 0.4 1.6 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like Synaptobrevin PF00957.21 KXX83478.1 - 0.04 13.7 0.5 0.66 9.8 0.1 2.0 1 1 1 2 2 2 0 Synaptobrevin Ysc84 PF04366.12 KXX83479.1 - 3.7e-39 133.4 0.2 6e-39 132.7 0.2 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KXX83479.1 - 1.3e-14 53.5 0.3 3.2e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXX83479.1 - 9.7e-12 44.6 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXX83479.1 - 2.8e-11 42.9 0.0 6.9e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KXX83479.1 - 0.031 14.0 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) PfkB PF00294.24 KXX83480.1 - 3.6e-15 56.0 0.2 3.4e-09 36.4 0.9 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXX83480.1 - 0.21 10.9 0.0 7.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Madurella_mycetomatis-ASM127576v2/GCA_001275765.2_ASM127576v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Madurella_mycetomatis-ASM127576v2/GCA_001275765.2_ASM127576v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Madurella_mycetomatis-ASM127576v2/GCA_001275765.2_ASM127576v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Madurella_mycetomatis-ASM127576v2/GCA_001275765.2_ASM127576v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 23:22:30 2019 # [ok]