# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Polyketide_cyc2 PF10604.4 CAR21032.1 - 2.3e-07 31.0 0.0 2.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 CAR21032.1 - 0.0085 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DJ-1_PfpI PF01965.19 CAR21034.1 - 4.5e-34 117.0 0.2 5.4e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CAR21034.1 - 3.4e-13 49.2 0.0 5.6e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 CAR21034.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CAR21034.1 - 0.00046 19.8 0.0 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 CAR21034.1 - 0.001 18.5 0.1 0.0044 16.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 CAR21034.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family GATase_5 PF13507.1 CAR21034.1 - 0.13 11.1 0.0 0.5 9.2 0.0 1.9 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUP PF00674.13 CAR21035.1 - 0.00041 20.2 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 DUP family AA_permease PF00324.16 CAR21036.1 - 4e-89 299.1 38.1 4.9e-89 298.8 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR21036.1 - 1.8e-23 82.7 45.9 1.2e-22 80.1 32.1 1.9 1 1 0 1 1 1 1 Amino acid permease FMN_bind_2 PF04299.7 CAR21037.1 - 2.1e-54 183.5 0.0 3.6e-54 182.7 0.0 1.4 1 1 0 1 1 1 1 Putative FMN-binding domain Pyridox_ox_2 PF12900.2 CAR21037.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ADH_N PF08240.7 CAR21038.1 - 2e-28 98.2 0.2 4.1e-28 97.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR21038.1 - 7.6e-27 93.4 0.4 1.1e-26 92.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR21038.1 - 0.00011 23.0 0.0 0.0002 22.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 CAR21038.1 - 0.038 13.5 0.4 0.064 12.8 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MFS_1 PF07690.11 CAR21039.1 - 2.6e-29 102.0 23.4 2.6e-29 102.0 16.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 CAR21039.1 - 5.9 5.3 8.7 0.25 9.8 1.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) IU_nuc_hydro PF01156.14 CAR21040.1 - 8.8e-47 159.8 0.4 1.1e-46 159.4 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ATP-synt_DE_N PF02823.11 CAR21040.1 - 0.055 13.2 0.0 8 6.2 0.0 3.1 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Transketolase_C PF02780.15 CAR21040.1 - 0.11 12.4 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fungal_trans_2 PF11951.3 CAR21041.1 - 2.1e-43 148.4 0.0 2.5e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR21041.1 - 0.0001 22.1 12.8 0.00021 21.1 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3733 PF12534.3 CAR21041.1 - 0.25 10.6 1.5 0.37 10.1 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 ApbA_C PF08546.6 CAR21042.1 - 1.6e-32 112.0 0.0 3.3e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CAR21042.1 - 2e-25 88.9 0.0 2.9e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.16 CAR21043.1 - 3e-51 173.9 0.0 3.7e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flo11 PF10182.4 CAR21044.1 - 6.7e-40 136.1 1.9 2.2e-39 134.4 1.3 2.0 1 0 0 1 1 1 1 Flo11 domain Ferric_reduct PF01794.14 CAR21045.1 - 1.4e-16 60.7 14.2 1.4e-16 60.7 9.8 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAR21045.1 - 4.7e-12 45.7 0.0 9.1e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CAR21045.1 - 9.2e-08 32.1 0.0 7.5e-05 22.6 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Peptidase_M16 PF00675.15 CAR21046.1 - 1.5e-24 86.4 0.0 2.3e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR21046.1 - 1.7e-12 47.3 0.1 4.8e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 CAR21047.1 - 1.4e-52 178.8 0.0 2.3e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 CAR21047.1 - 1.4e-22 79.3 3.8 3.1e-19 68.5 0.2 3.7 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 CAR21047.1 - 2.2e-09 36.7 0.4 2.1e-05 23.9 0.0 2.9 3 0 0 3 3 3 2 TFIIE alpha subunit HTH_IclR PF09339.5 CAR21047.1 - 5.5e-05 22.6 0.1 0.00022 20.7 0.1 2.0 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 CAR21047.1 - 0.00093 18.5 0.0 0.023 14.0 0.1 3.1 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 CAR21047.1 - 0.0056 16.3 0.6 0.024 14.3 0.1 2.3 2 0 0 2 2 2 1 MarR family TrmB PF01978.14 CAR21047.1 - 0.0094 15.6 1.7 0.13 11.9 0.0 3.3 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.11 CAR21047.1 - 0.032 14.3 0.0 0.097 12.7 0.0 1.9 1 0 0 1 1 1 0 Penicillinase repressor TPR_11 PF13414.1 CAR21048.1 - 3e-33 113.2 15.5 9.1e-08 31.6 0.0 9.7 8 3 3 11 11 10 10 TPR repeat TPR_16 PF13432.1 CAR21048.1 - 1.9e-31 107.9 7.1 6.1e-08 33.1 0.0 10.2 7 3 3 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 CAR21048.1 - 5.1e-26 90.7 2.2 1.4e-06 28.4 0.0 9.2 7 3 2 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAR21048.1 - 4.2e-24 82.8 3.6 0.0011 19.3 0.0 13.0 9 4 6 15 15 14 5 Tetratricopeptide repeat TPR_2 PF07719.12 CAR21048.1 - 1.4e-22 77.7 17.0 0.00023 20.8 0.0 13.4 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_1 PF00515.23 CAR21048.1 - 3.8e-20 70.5 13.3 0.00014 21.3 0.0 12.3 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_6 PF13174.1 CAR21048.1 - 4.8e-15 54.9 0.4 0.056 13.9 0.0 9.9 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAR21048.1 - 1.7e-13 49.5 9.9 0.043 14.0 0.0 11.6 13 0 0 13 13 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAR21048.1 - 3.8e-11 41.9 18.4 0.0031 17.1 0.0 10.3 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR21048.1 - 5.3e-11 42.2 21.0 0.0079 16.1 0.0 9.7 7 3 4 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR21048.1 - 2.1e-10 39.5 7.4 0.047 13.5 0.0 9.2 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 CAR21048.1 - 3.4e-09 36.6 21.1 8.8e-06 25.7 0.0 7.3 8 1 0 8 8 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CAR21048.1 - 1.5e-05 24.7 2.8 0.44 10.4 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.9 CAR21048.1 - 0.00011 21.4 3.3 0.0011 18.2 0.2 3.3 3 1 0 3 3 3 1 Coatomer epsilon subunit DUF1450 PF07293.6 CAR21048.1 - 0.0066 16.4 0.0 0.029 14.3 0.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF1450) PPR PF01535.15 CAR21048.1 - 0.02 14.8 0.6 15 5.8 0.0 3.9 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.1 CAR21048.1 - 0.022 14.7 4.8 27 4.8 0.4 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_20 PF14561.1 CAR21048.1 - 0.027 14.5 8.8 2.7 8.1 0.0 6.4 6 3 3 9 9 7 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 CAR21048.1 - 0.054 12.9 0.0 0.45 9.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_5 PF12688.2 CAR21048.1 - 0.078 13.0 0.2 0.84 9.6 0.0 2.9 2 0 0 2 2 2 0 Tetratrico peptide repeat Fis1_TPR_C PF14853.1 CAR21048.1 - 0.079 12.8 4.9 8 6.4 0.1 5.4 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Chlorophyllase PF07224.6 CAR21048.1 - 0.085 11.6 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase RNA_pol_Rpb6 PF01192.17 CAR21049.1 - 2e-23 81.8 0.3 3.4e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 CAR21050.1 - 1.4e-30 103.7 63.7 1.6e-05 24.9 3.0 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR21050.1 - 5e-27 92.1 65.1 5.3e-05 23.2 1.4 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR21050.1 - 4.8e-18 64.4 68.3 2.3e-05 24.4 3.1 10.5 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CAR21050.1 - 2.6e-10 40.1 34.8 0.023 14.8 0.2 8.3 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR21050.1 - 3.8e-06 26.9 35.8 0.2 11.8 0.5 8.7 9 0 0 9 9 9 4 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CAR21050.1 - 0.017 15.0 2.8 0.017 15.0 1.9 5.9 4 1 2 6 6 6 0 Zinc ribbon domain zf-FCS PF06467.9 CAR21050.1 - 0.052 13.1 17.4 3.5 7.3 0.1 5.6 3 1 2 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_2 PF12756.2 CAR21050.1 - 0.14 12.2 41.3 0.36 10.9 7.7 6.3 2 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.1 CAR21050.1 - 0.18 11.7 0.1 0.18 11.7 0.1 5.4 2 1 3 5 5 5 0 CpXC protein zf-ribbon_3 PF13248.1 CAR21050.1 - 1.6 8.0 16.7 14 5.0 0.2 5.0 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 CAR21050.1 - 2.3 8.5 25.2 1.3 9.3 0.4 4.9 5 0 0 5 5 5 0 Recombinase zinc beta ribbon domain ATG13 PF10033.4 CAR21051.1 - 1.3e-65 221.0 0.0 2.6e-65 220.1 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 hDGE_amylase PF14701.1 CAR21052.1 - 3.6e-176 586.1 0.0 5.4e-176 585.6 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CAR21052.1 - 3.4e-121 404.4 0.0 5.3e-121 403.8 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CAR21052.1 - 4e-74 249.0 0.0 6.2e-74 248.4 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CAR21052.1 - 3e-22 78.2 0.0 1.1e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CAR21052.1 - 2.5e-08 33.7 0.0 3.3e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glycos_transf_2 PF00535.21 CAR21053.1 - 3.2e-28 98.5 0.0 4.6e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CAR21053.1 - 8.6e-08 32.2 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CAR21053.1 - 5.4e-06 25.6 0.0 7.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 LSM PF01423.17 CAR21054.1 - 5.1e-17 61.1 0.1 6.2e-17 60.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain TraT PF05818.7 CAR21054.1 - 0.088 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein PIG-U PF06728.8 CAR21055.1 - 4.3e-100 335.2 41.6 5.4e-100 334.9 28.9 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Sec23_trunk PF04811.10 CAR21056.1 - 2.4e-74 249.7 0.0 3.3e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CAR21056.1 - 6.5e-35 118.6 0.1 1.2e-34 117.7 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CAR21056.1 - 2.6e-29 101.5 0.1 5.1e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CAR21056.1 - 2e-14 52.8 5.5 3.4e-14 52.1 3.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CAR21056.1 - 3.2e-11 42.7 0.0 5.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-MIZ PF02891.15 CAR21056.1 - 0.025 14.1 1.2 0.049 13.1 0.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger ThiF PF00899.16 CAR21057.1 - 3e-19 69.1 0.0 6.6e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 ThiF family TetR_C_4 PF08359.6 CAR21057.1 - 0.097 12.6 0.1 0.7 9.8 0.1 2.2 1 1 1 2 2 2 0 YsiA-like protein, C-terminal region HDA2-3 PF11496.3 CAR21058.1 - 1.1e-83 280.5 0.0 1.1e-83 280.5 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF445 PF04286.7 CAR21058.1 - 0.031 13.8 15.1 0.055 12.9 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) NPV_P10 PF05531.7 CAR21058.1 - 0.18 12.0 11.6 31 4.9 2.2 4.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.27 CAR21059.1 - 1.1e-55 183.5 27.8 5.2e-14 51.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CAR21059.1 - 1.2e-05 25.1 0.0 0.028 14.1 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Prenyltrans PF00432.16 CAR21060.1 - 4.3e-62 205.3 3.0 9.6e-12 44.2 0.1 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CAR21060.1 - 5.8e-29 100.7 0.0 6.4e-11 42.6 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CAR21060.1 - 2.3e-10 40.4 0.0 4.3e-06 26.6 0.0 3.2 1 1 2 3 3 3 2 Prenyltransferase-like DNA_pol_E_B PF04042.11 CAR21061.1 - 7.3e-49 165.8 0.0 1.1e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NBP1 PF08537.5 CAR21062.1 - 1.3e-71 241.5 20.3 1.6e-70 237.9 14.0 2.4 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 SWIRM PF04433.12 CAR21062.1 - 0.037 14.1 2.1 3.9 7.6 0.2 2.8 2 1 0 2 2 2 0 SWIRM domain Spherulin4 PF12138.3 CAR21062.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 AAA PF00004.24 CAR21063.1 - 4.7e-43 146.5 0.0 1.1e-42 145.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CAR21063.1 - 9.9e-30 102.2 0.0 1.2e-28 98.7 0.1 2.6 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CAR21063.1 - 1.1e-21 76.5 3.0 2e-21 75.6 0.8 2.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 CAR21063.1 - 2.9e-06 28.1 0.3 1.5e-05 25.7 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CAR21063.1 - 8.5e-06 25.5 0.0 6e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAR21063.1 - 1.1e-05 25.5 0.7 0.0018 18.4 0.0 2.9 3 1 0 3 3 1 1 AAA domain IstB_IS21 PF01695.12 CAR21063.1 - 1.3e-05 24.7 0.0 3.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CAR21063.1 - 2.9e-05 23.9 0.1 0.00012 21.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CAR21063.1 - 3.7e-05 22.9 0.0 6.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CAR21063.1 - 9.1e-05 21.9 0.3 0.12 11.7 0.1 2.5 1 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 CAR21063.1 - 0.00017 20.5 0.0 0.0013 17.7 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CAR21063.1 - 0.00021 21.3 0.4 0.0012 18.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 CAR21063.1 - 0.00024 21.0 0.1 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAR21063.1 - 0.00032 20.8 0.1 0.022 14.9 0.0 2.9 3 0 0 3 3 3 1 RNA helicase TIP49 PF06068.8 CAR21063.1 - 0.00033 19.4 0.0 0.00057 18.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CAR21063.1 - 0.00044 20.2 0.1 0.0011 18.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 CAR21063.1 - 0.0026 16.9 0.2 0.12 11.4 0.0 2.8 1 1 2 3 3 3 1 Zeta toxin AAA_18 PF13238.1 CAR21063.1 - 0.0069 16.7 0.5 0.015 15.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain PhoH PF02562.11 CAR21063.1 - 0.022 13.9 0.1 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 CAR21063.1 - 0.032 13.9 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 CAR21063.1 - 0.034 13.3 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 CAR21063.1 - 0.042 13.7 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.22 CAR21063.1 - 0.044 14.0 0.3 0.88 9.8 0.0 2.6 2 1 1 3 3 2 0 ABC transporter NACHT PF05729.7 CAR21063.1 - 0.073 12.7 0.0 1.2 8.8 0.0 2.3 1 1 0 1 1 1 0 NACHT domain KaiC PF06745.8 CAR21063.1 - 0.076 12.1 0.1 8.9 5.3 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.1 CAR21063.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CAR21063.1 - 0.091 12.8 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 CAR21063.1 - 0.12 11.8 0.0 0.42 10.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 CAR21063.1 - 0.24 10.7 2.0 1.6 8.0 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain KTI12 PF08433.5 CAR21063.1 - 0.43 9.7 3.3 3 6.9 0.0 2.9 2 2 1 3 3 3 0 Chromatin associated protein KTI12 Pyridox_oxidase PF01243.15 CAR21064.1 - 5.8e-13 48.6 0.0 3.3e-12 46.2 0.0 2.2 3 1 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 CAR21064.1 - 0.00019 21.2 0.1 0.25 11.1 0.0 2.2 1 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 CAR21064.1 - 0.00065 19.4 0.1 0.0027 17.5 0.1 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PWWP PF00855.12 CAR21065.1 - 8.8e-15 54.6 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 PWWP domain MFS_1 PF07690.11 CAR21066.1 - 8.1e-32 110.3 28.7 8.1e-32 110.3 19.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OSCP PF00213.13 CAR21066.1 - 0.21 11.4 0.1 0.37 10.6 0.1 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF1282 PF06930.7 CAR21068.1 - 0.016 14.8 0.3 0.019 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Ribosomal_S19e PF01090.14 CAR21069.1 - 5.1e-56 187.9 0.1 5.6e-56 187.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18e PF00828.14 CAR21070.1 - 2.4e-24 86.1 0.1 2.4e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 MFS_1 PF07690.11 CAR21071.1 - 1.6e-26 92.8 38.0 1.6e-26 92.8 26.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR21071.1 - 0.043 12.4 36.1 0.061 11.8 11.3 2.5 2 2 0 2 2 2 0 Sugar (and other) transporter Redoxin PF08534.5 CAR21072.1 - 7.3e-29 100.1 0.3 8.4e-29 99.9 0.2 1.1 1 0 0 1 1 1 1 Redoxin PCI PF01399.22 CAR21073.1 - 0.00021 21.5 0.2 0.00056 20.2 0.1 1.8 1 0 0 1 1 1 1 PCI domain PIR PF00399.14 CAR21074.1 - 3.2e-06 26.2 6.3 3.2e-06 26.2 4.4 3.3 2 0 0 2 2 2 1 Yeast PIR protein repeat Med13_C PF06333.7 CAR21074.1 - 3.6 6.0 7.9 4.3 5.7 5.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal GCR1_C PF12550.3 CAR21075.1 - 7.9e-25 86.5 0.1 1.5e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Vps5 PF09325.5 CAR21075.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Vps5 C terminal like SlyX PF04102.7 CAR21075.1 - 0.35 11.2 3.5 0.51 10.7 0.3 2.7 2 1 0 2 2 2 0 SlyX DUF2201_N PF13203.1 CAR21075.1 - 1 8.4 7.3 1.2 8.2 4.3 1.6 1 1 1 2 2 2 0 Putative metallopeptidase domain NTP_transf_2 PF01909.18 CAR21076.1 - 1.1e-17 64.0 0.6 2.8e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CAR21076.1 - 5.1e-16 58.3 0.0 1.5e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase RF-1 PF00472.15 CAR21077.1 - 5.5e-16 58.3 0.3 7.5e-16 57.9 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain Mei5 PF10376.4 CAR21077.1 - 0.04 13.4 2.7 0.052 13.0 1.9 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein IFNGR1 PF07140.6 CAR21077.1 - 0.045 13.4 0.7 0.068 12.8 0.5 1.3 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) Pkinase PF00069.20 CAR21078.1 - 9.3e-67 224.9 0.1 1.4e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21078.1 - 2.1e-51 174.4 0.0 3.2e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CAR21078.1 - 5.3e-22 77.9 0.4 2.1e-21 76.0 0.3 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 CAR21078.1 - 3.2e-09 36.9 0.0 7.2e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CAR21078.1 - 4.2e-07 29.2 0.0 7.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 CAR21078.1 - 0.0031 17.7 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 CAR21078.1 - 0.028 14.1 0.2 0.15 11.8 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family MSP1_C PF07462.6 CAR21078.1 - 0.076 11.3 0.3 0.14 10.4 0.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sec7_N PF12783.2 CAR21079.1 - 1.2e-39 135.3 14.3 2.5e-39 134.4 1.9 5.1 6 0 0 6 6 6 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Pet20 PF08692.5 CAR21080.1 - 1.5e-07 31.3 0.1 9.1e-07 28.8 0.0 2.3 2 1 0 2 2 2 1 Mitochondrial protein Pet20 PalH PF08733.5 CAR21081.1 - 1.6e-91 306.7 11.9 1.9e-91 306.5 8.2 1.0 1 0 0 1 1 1 1 PalH/RIM21 RabGAP-TBC PF00566.13 CAR21082.1 - 1.2e-46 158.8 0.9 1.9e-46 158.2 0.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ubiquitin PF00240.18 CAR21083.1 - 6.1e-07 28.7 1.4 1.3e-06 27.7 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CAR21083.1 - 0.00024 20.9 0.1 0.00039 20.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Erf4 PF10256.4 CAR21084.1 - 3.2e-30 104.4 0.1 4.1e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TruB_N PF01509.13 CAR21085.1 - 6.2e-40 136.7 0.3 2.2e-38 131.7 0.0 2.6 3 0 0 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) Mid1 PF12929.2 CAR21086.1 - 3.4e-136 454.3 12.9 4.5e-136 453.9 9.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 CAR21086.1 - 0.078 13.3 5.7 0.56 10.5 0.6 2.5 1 1 0 2 2 2 0 Fz domain Big_5 PF13205.1 CAR21086.1 - 0.75 10.4 5.0 0.39 11.3 0.2 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain DNA_pol3_delta2 PF13177.1 CAR21087.1 - 3.6e-17 62.5 0.0 6.4e-15 55.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CAR21087.1 - 6.3e-17 62.0 0.0 1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CAR21087.1 - 2.6e-14 52.9 0.0 5.7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CAR21087.1 - 5e-08 32.0 0.0 5.7e-06 25.3 0.0 2.3 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CAR21087.1 - 3.7e-07 29.4 0.0 8.2e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 CAR21087.1 - 8.7e-07 28.6 0.1 1.6e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 CAR21087.1 - 2.4e-06 27.7 2.7 0.012 15.7 0.1 3.0 3 1 1 4 4 2 2 AAA domain AAA_16 PF13191.1 CAR21087.1 - 5e-06 26.6 0.0 2.4e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CAR21087.1 - 6.6e-06 26.0 0.1 2.3e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 CAR21087.1 - 9e-06 24.6 0.0 0.00018 20.3 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 CAR21087.1 - 0.00019 20.4 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 CAR21087.1 - 0.00019 20.8 0.0 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 CAR21087.1 - 0.00029 20.5 0.1 0.0017 18.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CAR21087.1 - 0.00068 19.2 0.1 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR21087.1 - 0.0012 19.1 0.0 0.0041 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 CAR21087.1 - 0.0017 17.9 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR21087.1 - 0.0019 19.0 0.0 0.0036 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CAR21087.1 - 0.0023 17.4 0.1 0.028 13.9 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 CAR21087.1 - 0.0025 17.2 0.1 0.035 13.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CAR21087.1 - 0.0028 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 CAR21087.1 - 0.0031 17.1 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR21087.1 - 0.0032 17.1 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CAR21087.1 - 0.0042 16.9 0.0 0.34 10.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CAR21087.1 - 0.0046 16.5 0.2 0.13 11.8 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 CAR21087.1 - 0.0059 16.0 0.4 1.9 7.8 0.0 2.5 1 1 2 3 3 3 1 AAA-like domain Arch_ATPase PF01637.13 CAR21087.1 - 0.0077 15.9 0.1 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase Mg_chelatase PF01078.16 CAR21087.1 - 0.0091 15.1 0.0 0.052 12.7 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CAR21087.1 - 0.023 14.5 0.3 0.068 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 CAR21087.1 - 0.028 13.3 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.17 CAR21087.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.6 1 1 0 1 1 1 0 RNA helicase RFC1 PF08519.7 CAR21087.1 - 0.043 13.5 0.2 6 6.6 0.1 2.4 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain AAA_28 PF13521.1 CAR21087.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CAR21087.1 - 0.049 12.8 0.2 6 6.0 0.0 2.3 1 1 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 CAR21087.1 - 0.098 11.6 0.1 0.33 9.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 CAR21087.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.4 1 1 0 1 1 1 0 SNF2 family N-terminal domain MFS_1 PF07690.11 CAR21088.1 - 1.2e-09 37.3 73.6 2.2e-06 26.6 12.2 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR21088.1 - 0.23 9.9 35.1 0.0084 14.7 7.6 3.1 3 1 1 4 4 4 0 Sugar (and other) transporter Cyclin_N PF00134.18 CAR21089.1 - 8.3e-19 67.4 0.0 1.3e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CAR21089.1 - 7.1e-11 42.7 0.0 1e-10 42.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Apolipoprotein PF01442.13 CAR21091.1 - 0.0027 17.2 14.9 0.0031 17.0 10.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Calsarcin PF05556.6 CAR21091.1 - 0.22 10.7 7.9 0.25 10.5 5.5 1.1 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) TMCO5 PF14992.1 CAR21091.1 - 1.1 8.3 11.1 1.2 8.2 7.7 1.1 1 0 0 1 1 1 0 TMCO5 family DUF883 PF05957.8 CAR21091.1 - 3 8.2 22.6 5 7.5 8.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.1 CAR21091.1 - 3.3 6.5 18.5 3.7 6.4 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HisKA_3 PF07730.8 CAR21091.1 - 3.6 8.0 10.5 3.4 8.0 0.7 2.3 1 1 1 2 2 2 0 Histidine kinase UDPGT PF00201.13 CAR21091.1 - 3.8 5.9 6.2 4.5 5.6 4.3 1.0 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Hydantoinase_A PF01968.13 CAR21091.1 - 4.1 6.4 8.5 5.7 5.9 5.9 1.4 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase DUF913 PF06025.7 CAR21091.1 - 5.1 5.7 11.2 5.6 5.5 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RRF PF01765.14 CAR21091.1 - 5.2 6.5 14.7 2.4 7.6 8.2 1.7 1 1 1 2 2 2 0 Ribosome recycling factor Peptidase_M32 PF02074.10 CAR21091.1 - 5.4 5.5 8.1 5.7 5.4 5.6 1.0 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF763 PF05559.6 CAR21091.1 - 6.3 5.6 8.5 7.1 5.4 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Pilt PF15453.1 CAR21091.1 - 6.7 6.3 16.1 7 6.2 11.1 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Mitofilin PF09731.4 CAR21091.1 - 7.2 5.1 26.2 7.6 5.0 18.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TMPIT PF07851.8 CAR21091.1 - 7.2 5.5 7.7 8.3 5.3 5.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 CAR21091.1 - 8.6 4.0 8.3 8.8 4.0 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rcd1 PF04078.8 CAR21092.1 - 7.7e-120 398.6 3.2 9.2e-120 398.3 2.2 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Med13_N PF11597.3 CAR21092.1 - 0.086 11.4 2.8 0.13 10.8 1.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal TFIIA PF03153.8 CAR21092.1 - 0.39 10.5 6.2 0.5 10.2 4.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CAR21092.1 - 0.92 7.6 10.9 1.2 7.2 7.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TSA PF03249.8 CAR21092.1 - 9.2 4.6 10.1 13 4.2 7.0 1.1 1 0 0 1 1 1 0 Type specific antigen Adaptin_N PF01602.15 CAR21093.1 - 5.3e-108 361.6 11.8 6.5e-108 361.3 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CAR21093.1 - 4.4e-47 159.6 5.2 4.4e-47 159.6 3.6 1.9 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CAR21093.1 - 1.3e-12 47.8 1.1 0.0015 18.7 0.0 4.7 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.17 CAR21093.1 - 0.00049 19.9 6.8 7.1 7.0 0.0 7.0 7 1 0 7 7 7 1 HEAT repeat DUF3355 PF11835.3 CAR21093.1 - 0.0033 17.2 0.5 0.0096 15.7 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3355) HEAT_EZ PF13513.1 CAR21093.1 - 0.23 12.0 4.4 0.89 10.1 0.1 3.8 4 0 0 4 4 4 0 HEAT-like repeat RRM_1 PF00076.17 CAR21094.1 - 1.7e-13 49.9 0.2 8.9e-06 25.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21094.1 - 2.8e-10 40.0 0.0 3.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR21094.1 - 6.3e-09 35.5 0.1 0.0013 18.4 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIS13 PF08202.6 CAR21094.1 - 0.0054 15.8 0.3 0.0054 15.8 0.2 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Limkain-b1 PF11608.3 CAR21094.1 - 0.012 15.4 0.1 0.65 9.7 0.0 2.7 2 0 0 2 2 2 0 Limkain b1 GAS PF13851.1 CAR21094.1 - 4 6.5 11.5 1.2 8.2 2.0 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding YchF-GTPase_C PF06071.8 CAR21095.1 - 9.4e-37 124.6 0.4 2.2e-36 123.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CAR21095.1 - 1.3e-12 47.7 0.0 5.3e-12 45.7 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 CAR21095.1 - 0.00018 21.2 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CAR21095.1 - 0.0069 15.6 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Dna2 PF08696.6 CAR21095.1 - 0.01 15.1 0.2 0.019 14.3 0.1 1.6 1 0 0 1 1 1 0 DNA replication factor Dna2 Cupin_2 PF07883.6 CAR21095.1 - 0.097 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DUF3236 PF11576.3 CAR21095.1 - 0.2 11.0 1.2 0.4 10.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) SCO1-SenC PF02630.9 CAR21096.1 - 6.6e-70 234.2 0.0 8.5e-70 233.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CAR21096.1 - 0.0001 21.9 0.0 0.00025 20.7 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CAR21096.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like Chitin_synth_1 PF01644.12 CAR21097.1 - 3.5e-77 257.7 0.8 3.5e-77 257.7 0.6 1.6 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_2 PF03142.10 CAR21097.1 - 3e-27 95.2 3.5 3.8e-19 68.4 0.0 2.9 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 CAR21097.1 - 8.3e-25 86.2 0.0 1.8e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 CAR21097.1 - 5.2e-10 39.5 0.0 6.1e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CAR21097.1 - 2e-08 34.1 0.3 2e-08 34.1 0.2 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Peptidase_M20 PF01546.23 CAR21098.1 - 6.3e-25 87.7 0.0 1.1e-24 86.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR21098.1 - 1.8e-06 27.6 0.0 8e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CAR21098.1 - 1.8e-05 24.5 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Chitin_synth_2 PF03142.10 CAR21099.1 - 4.3e-283 939.5 0.5 7.2e-283 938.7 0.1 1.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CAR21099.1 - 7.3e-19 68.2 0.0 2.5e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CAR21099.1 - 1.5e-15 57.6 0.0 7.7e-13 48.7 0.0 2.4 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CAR21099.1 - 1.2e-05 24.6 0.0 0.00011 21.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CAR21099.1 - 0.0002 21.0 0.0 0.0053 16.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.23 CAR21099.1 - 0.00029 20.5 0.0 0.0009 18.9 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Macro PF01661.16 CAR21100.1 - 4.7e-24 84.5 0.0 6.3e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Macro domain ABC2_membrane PF01061.19 CAR21101.1 - 7.7e-70 234.3 58.4 3e-42 144.1 8.1 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CAR21101.1 - 1.1e-38 132.6 0.0 4.7e-19 69.0 0.0 3.0 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CAR21101.1 - 3.1e-38 129.5 5.2 2.7e-33 113.6 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CAR21101.1 - 2.5e-09 37.0 0.0 8.9e-09 35.3 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CAR21101.1 - 5.7e-09 35.4 5.2 5.7e-09 35.4 3.6 4.0 3 1 1 4 4 3 1 ABC-2 family transporter protein DUF258 PF03193.11 CAR21101.1 - 7.9e-06 25.1 0.0 0.00025 20.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR21101.1 - 4.7e-05 22.8 0.0 0.0018 17.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 CAR21101.1 - 9.5e-05 22.4 0.1 0.71 9.7 0.0 3.9 3 1 0 4 4 4 1 AAA domain cobW PF02492.14 CAR21101.1 - 0.00022 20.7 0.1 0.00048 19.6 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CAR21101.1 - 0.00032 21.1 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CAR21101.1 - 0.00055 20.0 0.0 0.022 14.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 CAR21101.1 - 0.0018 17.5 0.0 1.3 8.1 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAR21101.1 - 0.002 18.1 0.6 0.055 13.4 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CAR21101.1 - 0.0038 16.7 0.3 0.073 12.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CAR21101.1 - 0.0054 17.0 0.0 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CAR21101.1 - 0.0058 16.2 0.1 0.14 11.7 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CAR21101.1 - 0.0074 16.2 0.0 0.31 11.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CAR21101.1 - 0.022 14.2 0.1 4.6 6.6 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 CAR21101.1 - 0.03 13.3 0.2 0.1 11.5 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_17 PF13207.1 CAR21101.1 - 0.056 14.2 0.0 0.3 11.9 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAR21101.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CAR21101.1 - 0.12 12.0 0.5 0.4 10.3 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 CAR21101.1 - 0.16 11.7 0.4 1.9 8.3 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain Dynamin_N PF00350.18 CAR21101.1 - 0.55 10.0 0.0 0.55 10.0 0.0 2.9 4 0 0 4 4 3 0 Dynamin family GalKase_gal_bdg PF10509.4 CAR21102.1 - 6.4e-20 70.1 0.0 1.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 CAR21102.1 - 1.5e-16 60.3 0.0 3.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CAR21102.1 - 1.9e-13 50.2 0.6 4.4e-13 49.0 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain NiFe_hyd_SSU_C PF14720.1 CAR21102.1 - 0.11 12.5 0.7 0.54 10.3 0.5 2.0 2 0 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Aldose_epim PF01263.15 CAR21103.1 - 2.7e-58 197.4 0.0 3.5e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 CAR21103.1 - 2.9e-52 177.4 0.0 5.6e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CAR21103.1 - 1.5e-22 79.3 0.1 2.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 CAR21103.1 - 2.2e-15 56.3 0.0 1.3e-13 50.4 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CAR21103.1 - 1.4e-14 53.5 0.0 8e-14 51.0 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CAR21103.1 - 2.5e-13 49.5 0.0 3.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 CAR21103.1 - 4e-10 39.8 0.0 6.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR21103.1 - 1.1e-08 34.9 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 CAR21103.1 - 7.3e-08 31.6 0.0 5e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CAR21103.1 - 1.3e-07 31.8 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CAR21103.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family E2 PF08199.6 CAR21103.1 - 0.46 10.0 3.7 0.18 11.4 0.2 2.1 2 0 0 2 2 2 0 Bacteriophage E2-like protein GalP_UDP_transf PF01087.17 CAR21104.1 - 4e-64 216.0 0.0 6.3e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CAR21104.1 - 1.5e-63 213.3 0.1 3.3e-63 212.1 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CAR21104.1 - 0.0014 19.0 0.0 0.023 15.2 0.0 2.3 2 0 0 2 2 2 1 HIT domain Antimicrobial10 PF08105.6 CAR21104.1 - 0.068 12.7 0.1 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Metchnikowin family Peptidase_M24 PF00557.19 CAR21105.1 - 1.5e-57 194.4 0.0 2e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CAR21105.1 - 6.3e-26 90.3 0.1 1.9e-25 88.8 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain UCH PF00443.24 CAR21106.1 - 2.9e-13 49.5 0.0 6.8e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CAR21106.1 - 2e-08 34.2 0.1 3.9e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein JAB PF01398.16 CAR21107.1 - 1.3e-34 118.3 0.3 1.3e-34 118.3 0.2 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CAR21107.1 - 1.7e-26 92.5 4.5 5e-26 91.0 3.1 1.8 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CAR21107.1 - 2.1e-08 33.6 0.0 3.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CAR21107.1 - 0.017 14.5 2.4 0.14 11.6 1.6 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) PGM_PMM_II PF02879.11 CAR21107.1 - 0.11 12.8 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PPI_Ypi1 PF07491.6 CAR21108.1 - 1.9e-22 78.6 16.1 1.9e-22 78.6 9.9 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.4 CAR21108.1 - 0.2 11.0 27.4 0.15 11.4 18.0 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TMEM151 PF14857.1 CAR21108.1 - 0.33 9.5 4.3 0.43 9.1 3.0 1.1 1 0 0 1 1 1 0 TMEM151 family YL1 PF05764.8 CAR21108.1 - 0.46 10.0 18.7 1.1 8.8 12.7 1.7 1 1 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 CAR21108.1 - 1.7 6.5 15.3 2.1 6.2 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nic96 PF04097.9 CAR21109.1 - 6.3e-214 711.6 11.4 8.2e-214 711.2 7.9 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Hat1_N PF10394.4 CAR21111.1 - 5.5e-35 120.8 0.6 1e-34 119.9 0.4 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 CAR21111.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR21111.1 - 0.078 13.1 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR21111.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EAP30 PF04157.11 CAR21112.1 - 6.5e-47 159.5 0.0 7.3e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PseudoU_synth_1 PF01416.15 CAR21113.1 - 1.6e-28 99.2 0.0 1e-18 67.6 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEAD PF00270.24 CAR21114.1 - 1.7e-38 131.7 0.1 5.2e-38 130.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR21114.1 - 1.9e-20 72.4 0.0 4.7e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAR21114.1 - 8.4e-17 60.4 0.1 1.9e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CAR21114.1 - 0.0047 16.7 1.9 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IncA PF04156.9 CAR21114.1 - 0.52 9.8 2.9 0.93 9.0 2.0 1.4 1 0 0 1 1 1 0 IncA protein MoeZ_MoeB PF05237.8 CAR21115.1 - 0.009 15.5 0.2 0.37 10.4 0.0 2.6 2 0 0 2 2 2 2 MoeZ/MoeB domain Pil1 PF13805.1 CAR21116.1 - 2.6e-150 499.0 0.4 2.9e-150 498.8 0.3 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 CAR21116.1 - 0.029 14.2 4.5 0.15 11.9 0.1 2.9 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit FlgN PF05130.7 CAR21116.1 - 2 8.6 5.2 8.7 6.5 0.8 2.7 2 1 0 2 2 2 0 FlgN protein PPR_2 PF13041.1 CAR21117.1 - 7.9e-14 51.3 1.0 2.8e-06 27.1 0.0 5.0 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 CAR21117.1 - 4.1e-07 29.7 0.2 0.52 10.7 0.0 5.0 4 0 0 4 4 4 2 Pentatricopeptide repeat domain mRNA_stabil PF13929.1 CAR21117.1 - 0.0052 15.7 0.1 0.47 9.3 0.0 2.5 2 0 0 2 2 2 2 mRNA stabilisation PPR PF01535.15 CAR21117.1 - 0.035 14.0 1.0 32 4.7 0.0 4.7 5 0 0 5 5 5 0 PPR repeat ydhR PF08803.6 CAR21117.1 - 0.079 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR Patched PF02460.13 CAR21118.1 - 8.2e-54 182.7 24.9 5e-51 173.5 17.3 3.1 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 CAR21118.1 - 3.5e-38 130.4 24.7 6.5e-38 129.5 4.9 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 CAR21118.1 - 0.00015 19.3 15.7 0.00025 18.6 9.7 1.9 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family zf-TFIIIC PF12660.2 CAR21119.1 - 2.4e-19 69.0 0.0 1.5e-18 66.4 0.0 2.3 3 0 0 3 3 3 1 Putative zinc-finger of transcription factor IIIC complex TEA PF01285.13 CAR21119.1 - 0.042 13.0 0.1 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 TEA/ATTS domain family DUF3312 PF11768.3 CAR21119.1 - 0.045 11.9 0.0 0.071 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) UDPGT PF00201.13 CAR21119.1 - 0.12 10.8 0.2 0.22 10.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Helicase_C_2 PF13307.1 CAR21120.1 - 5.5e-49 166.3 0.1 1.5e-48 164.9 0.1 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CAR21120.1 - 1.2e-42 145.2 0.0 3.3e-42 143.8 0.0 1.8 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 CAR21120.1 - 4.1e-05 23.4 0.1 0.0091 15.8 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR21120.1 - 0.002 17.6 0.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.11 CAR21120.1 - 0.014 14.6 0.1 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 CAR21120.1 - 0.014 15.5 1.8 2.1 8.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain MLTD_N PF06474.7 CAR21121.1 - 0.17 12.0 2.7 1.4 9.1 0.1 3.0 2 0 0 2 2 2 0 MltD lipid attachment motif Ribosomal_S16 PF00886.14 CAR21123.1 - 6.5e-26 89.8 0.1 8.3e-26 89.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 NUC173 PF08161.7 CAR21124.1 - 1.9e-68 229.7 0.2 2e-65 219.8 0.0 4.2 4 0 0 4 4 4 1 NUC173 domain HEAT PF02985.17 CAR21124.1 - 1e-05 25.1 0.1 0.68 10.1 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 CAR21124.1 - 0.0045 17.2 0.4 1.5 9.1 0.1 4.3 3 1 1 4 4 4 1 HEAT repeats Ipi1_N PF12333.3 CAR21124.1 - 0.016 15.1 0.1 3.1 7.8 0.0 3.7 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Skp1_POZ PF03931.10 CAR21124.1 - 0.042 13.9 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Bromo_TP PF07524.8 CAR21125.1 - 2.6e-05 23.8 0.0 5.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Clat_adaptor_s PF01217.15 CAR21126.1 - 8.9e-17 61.1 0.2 1.3e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3441 PF11923.3 CAR21127.1 - 1.8e-28 98.4 0.6 1.8e-28 98.4 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 CAR21127.1 - 4.3e-22 78.2 0.1 4.3e-22 78.2 0.1 3.6 3 1 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CAR21127.1 - 1.3e-08 34.5 0.3 5.3e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF814) SIR2 PF02146.12 CAR21128.1 - 5.4e-56 189.1 0.0 7.2e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Peptidase_C48 PF02902.14 CAR21129.1 - 1.5e-36 126.0 0.1 3.3e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF2481 PF10654.4 CAR21129.1 - 0.016 14.9 1.5 0.032 13.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) VTC PF09359.5 CAR21130.1 - 6.4e-94 314.1 0.0 1.3e-93 313.1 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CAR21130.1 - 3.3e-27 95.9 12.7 1.3e-15 57.9 4.6 3.6 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.10 CAR21130.1 - 5.2e-09 36.1 4.1 1.3e-08 34.9 2.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) MBOAT PF03062.14 CAR21130.1 - 0.013 14.6 0.5 0.021 13.9 0.3 1.2 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family Ras PF00071.17 CAR21131.1 - 3.6e-63 211.7 0.3 4.3e-63 211.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR21131.1 - 8.1e-20 71.4 0.1 1.2e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR21131.1 - 2.8e-19 69.0 0.1 3.4e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR21131.1 - 5.7e-08 32.1 0.0 6.8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR21131.1 - 8.2e-08 31.6 0.1 1.1e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CAR21131.1 - 6.2e-06 26.1 0.1 9.7e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR21131.1 - 9.2e-06 25.2 0.2 8.3e-05 22.0 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CAR21131.1 - 0.00046 19.4 0.1 0.0055 15.9 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 CAR21131.1 - 0.0076 15.4 0.0 0.01 15.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 CAR21131.1 - 0.01 16.0 0.0 0.58 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR21131.1 - 0.011 15.9 0.0 0.029 14.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 CAR21131.1 - 0.012 14.3 0.7 0.42 9.2 0.0 2.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 CAR21131.1 - 0.014 15.3 0.2 0.026 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.18 CAR21131.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_29 PF13555.1 CAR21131.1 - 0.022 14.2 0.1 0.076 12.5 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.8 CAR21131.1 - 0.097 11.5 0.1 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF3437 PF11919.3 CAR21132.1 - 2.9e-28 97.4 0.0 9.6e-28 95.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) SMC_N PF02463.14 CAR21133.1 - 1e-54 185.1 35.4 4.4e-54 183.0 24.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAR21133.1 - 3.2e-26 91.6 0.0 1.2e-25 89.7 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CAR21133.1 - 1.7e-14 54.6 12.5 1.7e-14 54.6 8.7 6.3 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 CAR21133.1 - 2.2e-10 40.9 18.3 0.00013 22.0 6.4 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CAR21133.1 - 7.4e-09 35.0 0.1 2e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR21133.1 - 0.12 13.2 3.3 0.3 11.9 0.0 3.5 3 1 0 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 CAR21133.1 - 0.48 9.5 38.3 0.6 9.2 0.3 5.5 3 1 3 6 6 6 0 Reovirus sigma C capsid protein WD40 PF00400.27 CAR21135.1 - 2.4e-45 150.8 16.9 1.4e-11 43.8 1.1 7.7 8 1 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 CAR21135.1 - 1.1e-09 37.8 0.1 2.4e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR21135.1 - 6.1e-08 32.1 0.8 1.4e-07 30.9 0.6 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 CAR21135.1 - 3.3e-05 22.8 0.7 0.23 10.1 0.1 2.9 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 CAR21135.1 - 0.00039 18.7 5.7 0.2 9.7 0.1 4.8 3 2 1 4 4 4 2 Nucleoporin Nup120/160 PRANC PF09372.5 CAR21135.1 - 0.019 14.8 0.6 0.054 13.4 0.0 2.1 2 0 0 2 2 2 0 PRANC domain JmjC PF02373.17 CAR21135.1 - 0.023 14.9 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase Amelogenin PF02948.10 CAR21135.1 - 0.26 11.9 0.5 0.43 11.1 0.3 1.4 1 0 0 1 1 1 0 Amelogenin DAO PF01266.19 CAR21136.1 - 5e-14 51.9 0.0 9.5e-14 51.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CAR21136.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding WW PF00397.21 CAR21137.1 - 1.3e-06 28.1 0.2 4.7e-06 26.3 0.1 2.0 1 0 0 1 1 1 1 WW domain Pro-rich PF15240.1 CAR21137.1 - 0.014 15.5 31.1 0.023 14.8 21.6 1.3 1 0 0 1 1 1 0 Proline-rich DUF605 PF04652.11 CAR21137.1 - 0.12 11.6 13.0 0.13 11.6 9.0 1.0 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CAR21137.1 - 8.8 4.4 24.3 10 4.2 16.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HSP9_HSP12 PF04119.7 CAR21140.1 - 4.8e-26 90.6 9.3 7.4e-26 90.0 3.5 2.1 2 0 0 2 2 2 1 Heat shock protein 9/12 PhageMin_Tail PF10145.4 CAR21140.1 - 0.017 14.8 2.5 0.022 14.3 1.8 1.1 1 0 0 1 1 1 0 Phage-related minor tail protein DUF357 PF04010.8 CAR21140.1 - 0.052 13.2 1.7 0.37 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF883 PF05957.8 CAR21140.1 - 0.23 11.8 2.9 0.99 9.8 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 CAR21140.1 - 2 8.8 6.8 91 3.5 4.7 2.3 1 1 0 1 1 1 0 YtxH-like protein DnaJ PF00226.26 CAR21141.1 - 2.2e-23 81.7 2.9 3.8e-23 81.0 2.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR21141.1 - 1.2e-21 76.3 0.2 2.1e-16 59.6 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAR21141.1 - 7.6e-12 45.1 17.4 1.3e-11 44.4 12.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CAR21141.1 - 0.034 13.8 1.0 0.034 13.8 0.7 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF3006 PF11213.3 CAR21141.1 - 0.059 13.1 0.0 0.21 11.3 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) Coatomer_WDAD PF04053.9 CAR21141.1 - 0.15 10.7 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Sporozoite_P67 PF05642.6 CAR21141.1 - 0.35 8.6 7.3 0.47 8.2 5.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Antiterm PF03589.8 CAR21141.1 - 4.9 7.3 9.0 76 3.5 0.1 3.6 1 1 2 3 3 3 0 Antitermination protein zf-IS66 PF13005.2 CAR21141.1 - 4.9 7.2 6.2 66 3.5 0.0 3.4 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 DUF2781 PF10914.3 CAR21142.1 - 3.2e-34 117.8 7.1 3.9e-34 117.6 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ACPS PF01648.15 CAR21142.1 - 0.16 11.8 0.4 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Acetyltransf_1 PF00583.19 CAR21144.1 - 3.2e-15 55.8 0.0 5.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR21144.1 - 4.2e-11 42.8 0.0 6.2e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR21144.1 - 5.1e-05 23.1 0.0 9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR21144.1 - 0.0092 16.0 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAR21144.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM PF01423.17 CAR21145.1 - 8.7e-18 63.6 0.1 9.7e-18 63.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain Pyr_redox_dim PF02852.17 CAR21146.1 - 1.1e-43 147.7 0.1 3.6e-43 146.0 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CAR21146.1 - 1.3e-39 136.2 10.5 2.5e-38 131.9 7.3 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR21146.1 - 2.6e-20 72.5 8.1 1.3e-18 67.1 0.3 4.1 3 1 2 5 5 5 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAR21146.1 - 4.6e-11 42.4 0.3 3.6e-09 36.2 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAR21146.1 - 1.2e-09 38.0 0.9 3.2e-05 23.8 0.1 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CAR21146.1 - 3.2e-08 32.8 7.9 5.1e-08 32.1 2.2 2.4 1 1 1 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CAR21146.1 - 3.5e-08 33.7 0.9 3.3e-05 24.0 0.3 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAR21146.1 - 7.4e-07 28.3 15.1 0.023 13.6 0.8 4.4 2 2 2 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR21146.1 - 1.1e-06 27.8 2.0 1.1e-06 27.8 1.4 2.7 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 CAR21146.1 - 1.7e-05 23.9 0.4 0.14 11.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CAR21146.1 - 1.9e-05 23.8 7.5 0.14 11.1 0.1 4.0 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 CAR21146.1 - 7.6e-05 21.9 2.3 0.0003 19.9 0.1 2.4 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.9 CAR21146.1 - 0.0015 17.1 11.5 0.025 13.0 0.4 4.2 3 2 1 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.16 CAR21146.1 - 0.0067 16.0 0.9 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.14 CAR21146.1 - 0.015 14.4 0.4 0.085 11.9 0.0 2.4 4 0 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 CAR21146.1 - 0.057 13.0 2.9 0.18 11.4 0.1 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1194 PF06707.6 CAR21146.1 - 0.072 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) PTS_IIB PF02302.12 CAR21146.1 - 0.21 12.0 3.3 12 6.4 0.1 3.8 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit GATA PF00320.22 CAR21147.1 - 2.8e-17 61.7 2.9 5.5e-17 60.8 2.0 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CAR21147.1 - 5.6e-08 32.2 0.9 1.1e-07 31.2 0.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 CAR21147.1 - 0.2 11.0 0.3 0.37 10.1 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Fcf2 PF08698.6 CAR21148.1 - 4.6e-35 119.5 3.6 9.5e-35 118.5 2.5 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Suppressor_APC PF11414.3 CAR21148.1 - 0.011 15.4 0.4 5.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein tRNA-synt_2d PF01409.15 CAR21150.1 - 6.4e-88 294.1 0.0 9.7e-88 293.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CAR21150.1 - 1.7e-06 27.7 0.1 4.1e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CAR21150.1 - 5.9e-06 25.2 2.3 0.00026 19.8 0.0 3.2 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) HTH_45 PF14947.1 CAR21150.1 - 0.011 15.4 2.8 0.26 11.1 0.2 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix PaaX PF07848.7 CAR21150.1 - 0.019 14.9 0.0 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 PaaX-like protein tRNA-synt_His PF13393.1 CAR21150.1 - 0.051 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase GCR1_C PF12550.3 CAR21153.1 - 2.6e-13 49.6 0.8 9.6e-10 38.2 0.2 2.4 2 0 0 2 2 2 2 Transcriptional activator of glycolytic enzymes DUF3835 PF12927.2 CAR21154.1 - 1.1e-19 71.1 4.3 4.6e-18 65.9 0.2 5.0 7 0 0 7 7 7 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 CAR21154.1 - 1.7e-10 40.5 4.4 2.4e-10 40.1 1.8 2.2 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 CAR21154.1 - 0.12 12.1 5.9 0.038 13.7 0.6 2.9 3 0 0 3 3 3 0 Prefoldin subunit EPL1 PF10513.4 CAR21155.1 - 2.4e-33 115.6 3.6 2.4e-33 115.6 2.5 3.2 3 0 0 3 3 3 2 Enhancer of polycomb-like Activator_LAG-3 PF11498.3 CAR21155.1 - 0.21 10.3 24.1 0.046 12.4 12.5 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PGAP1 PF07819.8 CAR21156.1 - 5.1e-85 284.6 0.0 7.7e-85 284.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2670 PF10875.3 CAR21156.1 - 0.0028 17.7 0.1 0.0093 15.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2670) Abhydrolase_5 PF12695.2 CAR21156.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CAR21156.1 - 0.0098 15.5 0.0 0.044 13.3 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) LCAT PF02450.10 CAR21156.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 CAR21156.1 - 0.023 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CAR21156.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family STE2 PF02116.10 CAR21157.1 - 4.7e-86 288.3 26.5 6e-86 287.9 18.4 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DENN PF02141.16 CAR21157.1 - 0.087 12.5 4.0 0.16 11.6 1.7 2.2 3 0 0 3 3 3 0 DENN (AEX-3) domain AA_permease_2 PF13520.1 CAR21158.1 - 4.6e-86 289.0 43.6 5.7e-86 288.6 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR21158.1 - 7.6e-18 64.1 41.7 1.1e-17 63.6 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease SIR2 PF02146.12 CAR21159.1 - 1.1e-31 109.9 0.0 9.9e-10 38.4 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Bromodomain PF00439.20 CAR21160.1 - 4.5e-31 106.6 3.9 1.7e-17 63.0 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 CAR21160.1 - 8.7e-23 80.3 0.1 2e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 BAH domain CENP-B_dimeris PF09026.5 CAR21160.1 - 0.66 10.2 16.1 0.29 11.3 0.4 3.1 3 1 1 4 4 4 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 CAR21160.1 - 6.9 6.4 13.8 3.7 7.3 1.4 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal Lyase_1 PF00206.15 CAR21161.1 - 8.4e-22 77.7 0.0 1.5e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CAR21161.1 - 1.7e-16 59.9 0.0 7.8e-16 57.8 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 CAR21161.1 - 0.037 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Anti-Sigma Factor A DUF1331 PF07048.6 CAR21161.1 - 0.083 12.3 1.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Folliculin PF11704.3 CAR21162.1 - 2.6e-44 150.7 0.1 3.2e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Mtc PF03820.12 CAR21162.1 - 0.011 14.4 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier SWIRM PF04433.12 CAR21163.1 - 3.9e-31 106.9 0.1 1e-30 105.6 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 CAR21163.1 - 2.7e-14 52.4 3.7 4.4e-14 51.7 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CAR21163.1 - 6.4e-06 26.1 0.1 1.7e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR21163.1 - 1.4e-05 25.0 0.1 0.00013 21.9 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain THOC7 PF05615.8 CAR21163.1 - 0.00045 20.4 12.0 0.00045 20.4 8.3 2.6 2 1 0 2 2 2 1 Tho complex subunit 7 zf-UBR PF02207.15 CAR21163.1 - 0.11 12.2 1.5 0.21 11.3 1.1 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Elf1 PF05129.8 CAR21163.1 - 0.17 11.5 1.8 0.19 11.4 0.2 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF45 PF01863.12 CAR21163.1 - 6.2 6.5 10.4 27 4.4 3.3 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF45 SNF2_N PF00176.18 CAR21164.1 - 7.4e-68 228.5 0.7 1.5e-67 227.5 0.2 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR21164.1 - 1.3e-21 76.1 0.1 2.2e-18 65.8 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CAR21164.1 - 2.3e-07 29.9 0.0 1e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CAR21164.1 - 1.4e-06 27.8 0.0 4.2e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase cNMP_binding PF00027.24 CAR21165.1 - 1.5e-45 152.8 0.1 1e-22 79.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CAR21165.1 - 1.6e-09 37.0 3.9 4.7e-09 35.5 2.7 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.6 CAR21165.1 - 0.0055 16.1 2.7 1.1 8.7 0.3 2.6 2 0 0 2 2 2 2 Cupin domain ATP-synt_DE_N PF02823.11 CAR21165.1 - 0.2 11.4 0.3 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Erg28 PF03694.8 CAR21166.1 - 5.2e-43 145.5 1.1 6.8e-43 145.2 0.8 1.1 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.11 CAR21166.1 - 0.01 15.6 1.8 0.014 15.2 0.2 1.9 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange Fzo_mitofusin PF04799.8 CAR21166.1 - 0.027 13.8 0.1 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 fzo-like conserved region TctB PF07331.6 CAR21166.1 - 0.036 13.7 0.1 0.051 13.2 0.1 1.3 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family UPF0239 PF06783.6 CAR21166.1 - 0.11 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Aldo_ket_red PF00248.16 CAR21167.1 - 9.8e-53 178.8 0.0 1.2e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 CAR21168.1 - 5e-07 29.5 9.3 9.9e-07 28.5 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CAR21168.1 - 0.016 14.1 0.0 0.05 12.4 0.0 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain F_actin_cap_B PF01115.12 CAR21169.1 - 2e-95 318.6 0.0 2.3e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pkinase PF00069.20 CAR21170.1 - 6.4e-56 189.3 5.6 2.9e-54 183.9 3.9 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21170.1 - 6.6e-19 67.9 2.1 2.8e-14 52.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CAR21170.1 - 1.7e-05 24.6 0.0 6.8e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAR21170.1 - 0.0054 16.3 0.3 0.015 14.8 0.2 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CAR21170.1 - 0.037 13.1 0.1 0.08 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.16 CAR21172.1 - 2e-15 56.4 7.9 2.9e-15 55.9 5.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CAR21172.1 - 7.8e-09 35.2 7.0 1.3e-08 34.5 4.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CAR21172.1 - 0.0082 16.4 6.6 0.017 15.3 4.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor FemAB PF02388.11 CAR21172.1 - 0.016 13.9 0.4 0.022 13.4 0.3 1.2 1 0 0 1 1 1 0 FemAB family Streptin-Immun PF11083.3 CAR21172.1 - 0.094 12.7 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein TFIIA PF03153.8 CAR21172.1 - 0.34 10.7 12.0 0.42 10.4 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CAR21172.1 - 3.9 5.6 26.4 6.2 4.9 18.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4476 PF14771.1 CAR21173.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4476) GED PF02212.13 CAR21174.1 - 0.0047 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF104 PF01954.11 CAR21174.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 Not3 PF04065.10 CAR21175.1 - 8.1e-90 300.1 26.7 8.1e-90 300.1 18.5 2.6 2 1 1 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CAR21175.1 - 4.5e-25 88.0 0.0 1.6e-24 86.3 0.0 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family TauD PF02668.11 CAR21176.1 - 5.1e-48 163.9 0.0 8.1e-48 163.3 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 CAR21176.1 - 0.011 16.2 0.6 0.62 10.6 0.0 2.6 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily AAA PF00004.24 CAR21177.1 - 4.4e-40 136.9 0.0 8.3e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CAR21177.1 - 1.1e-07 31.6 0.0 2.1e-05 24.3 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CAR21177.1 - 2e-05 23.7 0.0 7.1e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CAR21177.1 - 2.1e-05 24.6 0.1 0.00023 21.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR21177.1 - 4.7e-05 23.4 0.0 0.017 15.1 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 CAR21177.1 - 5.5e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CAR21177.1 - 0.00038 20.2 0.0 0.0014 18.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CAR21177.1 - 0.00047 18.9 0.0 0.00081 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 CAR21177.1 - 0.0011 18.8 0.0 0.02 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR21177.1 - 0.0034 16.8 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CAR21177.1 - 0.0036 16.4 0.1 0.0077 15.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CAR21177.1 - 0.0038 18.0 2.0 0.037 14.8 0.0 3.1 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CAR21177.1 - 0.0047 16.6 0.0 0.78 9.3 0.0 2.8 1 1 1 2 2 2 1 Archaeal ATPase DUF815 PF05673.8 CAR21177.1 - 0.006 15.5 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 CAR21177.1 - 0.0072 16.0 0.0 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CAR21177.1 - 0.0077 15.6 2.8 0.22 10.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 CAR21177.1 - 0.013 15.8 0.6 0.14 12.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.1 CAR21177.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CAR21177.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CAR21177.1 - 0.051 13.2 0.1 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 CAR21177.1 - 0.067 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Chromo PF00385.19 CAR21177.1 - 0.076 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PhoH PF02562.11 CAR21177.1 - 0.099 11.8 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Metallophos PF00149.23 CAR21178.1 - 5.2e-28 97.8 6.8 5.2e-28 97.8 4.7 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DnaJ-X PF14308.1 CAR21179.1 - 2.8e-65 219.4 8.3 8.8e-65 217.8 6.1 1.6 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CAR21179.1 - 3.3e-26 90.7 3.2 4.2e-26 90.4 1.1 2.2 2 0 0 2 2 2 1 DnaJ domain PAP_central PF04928.12 CAR21179.1 - 0.0075 15.1 0.8 0.01 14.7 0.6 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain Apq12 PF12716.2 CAR21180.1 - 7.4e-09 35.1 6.2 7.4e-09 35.1 4.3 1.6 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Complex1_LYR PF05347.10 CAR21181.1 - 3.3e-16 58.8 0.2 4.5e-16 58.3 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAR21181.1 - 1.1e-15 57.6 0.4 1.3e-15 57.3 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Ofd1_CTDD PF10637.4 CAR21182.1 - 7.5e-95 317.0 2.7 6.4e-91 304.1 2.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CAR21182.1 - 2.6e-16 59.9 0.3 2.3e-15 56.9 0.2 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BAR_2 PF10455.4 CAR21183.1 - 5.8e-83 278.1 13.9 5.8e-83 278.1 9.6 2.3 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CAR21183.1 - 9.7e-18 64.5 14.6 9.7e-18 64.5 10.1 2.7 1 1 1 2 2 2 1 BAR domain Atg14 PF10186.4 CAR21183.1 - 0.0075 15.2 14.8 0.064 12.1 3.9 2.2 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Senescence PF06911.7 CAR21183.1 - 0.028 14.1 2.2 0.22 11.2 1.5 2.2 1 1 0 1 1 1 0 Senescence-associated protein Glyco_transf_5 PF08323.6 CAR21183.1 - 0.038 13.4 0.1 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Plasmid_parti PF01672.11 CAR21183.1 - 0.16 12.3 1.5 1.1 9.6 1.0 2.4 1 1 0 1 1 1 0 Putative plasmid partition protein DUF1090 PF06476.7 CAR21183.1 - 1.3 8.6 11.0 9.2 5.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) CCDC84 PF14968.1 CAR21183.1 - 1.7 8.1 6.7 5.8 6.3 4.6 1.9 1 1 0 1 1 1 0 Coiled coil protein 84 Syntaxin-6_N PF09177.6 CAR21183.1 - 4.3 7.8 16.2 3.5 8.0 1.5 4.0 2 2 0 4 4 4 0 Syntaxin 6, N-terminal BCDHK_Adom3 PF10436.4 CAR21184.1 - 1e-26 93.4 0.3 1.5e-26 92.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CAR21184.1 - 5.3e-20 71.1 0.0 9.3e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CAR21184.1 - 4.7e-06 26.3 0.0 7.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CAR21184.1 - 0.037 13.8 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ribosomal_S18 PF01084.15 CAR21185.1 - 2.4e-19 68.9 0.0 5.4e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 PHD PF00628.24 CAR21186.1 - 1.4e-06 27.8 2.0 2.5e-06 27.0 1.4 1.4 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.1 CAR21186.1 - 3.6e-05 23.4 0.0 0.00017 21.1 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CAR21186.1 - 0.0027 17.0 0.0 0.0051 16.1 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein zf-HC5HC2H PF13771.1 CAR21186.1 - 0.0058 16.7 1.0 0.013 15.6 0.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_1 PF00130.17 CAR21186.1 - 0.01 15.5 1.8 0.02 14.6 1.2 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) JmjC PF02373.17 CAR21186.1 - 0.021 15.0 0.0 0.084 13.1 0.0 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_1 PF00190.17 CAR21186.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Cupin zf-HC5HC2H_2 PF13832.1 CAR21186.1 - 0.08 12.9 1.2 0.15 12.0 0.8 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain NAD_binding_1 PF00175.16 CAR21187.1 - 6.3e-30 103.9 0.0 1e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAR21187.1 - 4.2e-27 94.1 0.0 7.5e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAR21187.1 - 8.6e-05 22.4 0.0 0.076 12.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CAR21187.1 - 0.054 13.4 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain AA_kinase PF00696.23 CAR21188.1 - 1.3e-40 139.4 0.0 3.3e-40 138.1 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 CAR21188.1 - 5.9e-15 54.3 0.2 5e-08 32.2 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 CAR21188.1 - 6.2e-10 38.4 1.6 2.8e-07 29.9 0.2 2.5 2 0 0 2 2 2 2 ACT domain Cyt-b5 PF00173.23 CAR21189.1 - 9.5e-21 73.3 0.0 1.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ArfGap PF01412.13 CAR21190.1 - 1.5e-36 124.7 0.6 2.3e-36 124.1 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Mito_carr PF00153.22 CAR21191.1 - 1.6e-44 149.5 4.3 4.2e-15 55.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBM_21 PF03370.8 CAR21192.1 - 1.7e-27 95.6 0.0 2.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit WD40 PF00400.27 CAR21193.1 - 1.5e-47 157.8 31.6 1.2e-08 34.4 0.9 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 CAR21193.1 - 3e-15 55.6 0.4 6.8e-15 54.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR21193.1 - 8.4e-12 44.4 0.2 1.8e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 CAR21193.1 - 1.2e-09 36.9 12.1 0.012 13.7 0.2 6.0 3 2 3 6 6 6 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 CAR21193.1 - 0.01 15.5 0.0 3.6 7.3 0.0 3.5 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 CAR21193.1 - 0.014 14.1 1.6 11 4.6 0.0 3.5 1 1 1 4 4 4 0 Nup133 N terminal like PQQ_2 PF13360.1 CAR21193.1 - 0.05 13.0 0.2 0.38 10.1 0.1 2.1 2 0 0 2 2 2 0 PQQ-like domain PRANC PF09372.5 CAR21193.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 PRANC domain HisG PF01634.13 CAR21194.1 - 9.4e-54 181.3 0.1 1.4e-53 180.8 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CAR21194.1 - 8.6e-30 102.5 0.0 1.4e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain EXS PF03124.9 CAR21195.1 - 2.3e-85 286.6 25.2 3.3e-85 286.1 17.4 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CAR21195.1 - 4.2e-41 141.5 1.9 1.1e-40 140.1 1.3 1.7 1 1 0 1 1 1 1 SPX domain E1-E2_ATPase PF00122.15 CAR21196.1 - 2.9e-27 95.2 0.1 6.2e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CAR21196.1 - 4.8e-14 53.2 0.0 9.8e-13 49.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR21196.1 - 2.8e-09 37.3 0.5 8.3e-09 35.8 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR21196.1 - 1.7e-07 31.1 0.0 4.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR21196.1 - 0.0029 17.2 0.2 0.0081 15.7 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L34e PF01199.13 CAR21197.1 - 4.4e-37 126.1 3.4 4.4e-37 126.1 2.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e Ribonuc_L-PSP PF01042.16 CAR21198.1 - 1.9e-41 140.6 0.7 2.3e-41 140.3 0.5 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4294 PF14127.1 CAR21199.1 - 0.035 13.6 0.2 0.051 13.1 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4294) Ctr PF04145.10 CAR21199.1 - 0.062 13.3 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Cyclin PF08613.6 CAR21200.1 - 1.4e-46 158.6 2.1 1.5e-46 158.5 0.5 1.7 2 0 0 2 2 2 1 Cyclin Transp_cyt_pur PF02133.10 CAR21201.1 - 6.8e-84 281.9 38.6 8e-84 281.7 26.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Steroid_dh PF02544.11 CAR21202.1 - 7.3e-16 58.2 4.3 8.3e-16 58.1 2.0 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 CAR21202.1 - 6.6e-07 29.4 2.8 1.9e-05 24.6 0.3 2.6 2 1 0 2 2 2 2 Phospholipid methyltransferase DUF998 PF06197.8 CAR21202.1 - 0.24 10.6 8.0 0.037 13.3 1.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF998) ketoacyl-synt PF00109.21 CAR21203.1 - 9.2e-56 189.1 0.1 1.3e-55 188.6 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CAR21203.1 - 3.6e-32 110.7 1.6 6.8e-32 109.8 1.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 CAR21203.1 - 0.015 14.2 0.1 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain HAD_2 PF13419.1 CAR21204.1 - 6.7e-12 45.9 0.0 8.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR21204.1 - 5e-08 32.5 0.0 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CAR21204.1 - 2.4e-07 31.4 0.0 3.5e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR21204.1 - 0.089 12.9 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR21205.1 - 1.6e-13 51.2 0.0 2.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR21205.1 - 4e-09 37.2 0.0 5.9e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR21205.1 - 2e-06 27.4 0.0 4.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CAR21205.1 - 0.0044 17.2 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SAP PF02037.22 CAR21206.1 - 1.8e-11 43.2 0.0 3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 SAP domain Trypan_PARP PF05887.6 CAR21206.1 - 0.00016 21.5 18.0 0.00028 20.7 12.5 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) HeH PF12949.2 CAR21206.1 - 0.036 13.6 0.1 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain DUF4106 PF13388.1 CAR21206.1 - 2.4 7.0 8.9 3 6.6 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Vhr1 PF04001.8 CAR21208.1 - 9.5e-46 153.6 3.7 9.5e-46 153.6 2.5 2.0 3 0 0 3 3 3 1 Transcription factor Vhr1 ICL PF00463.16 CAR21209.1 - 8e-265 878.9 0.7 9.1e-265 878.7 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CAR21209.1 - 1.7e-09 37.2 0.0 7.2e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2578 PF10843.3 CAR21210.1 - 5.6e-62 208.8 15.9 6.7e-62 208.6 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) zf-RING_4 PF14570.1 CAR21211.1 - 1e-19 69.8 12.9 2.1e-19 68.7 9.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 CAR21211.1 - 2e-06 27.2 0.2 0.00019 20.9 0.1 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 CAR21211.1 - 3.8e-06 26.6 4.0 1.1e-05 25.1 2.8 1.8 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 CAR21211.1 - 2.4e-05 24.1 1.0 0.00015 21.5 0.7 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CAR21211.1 - 3.5e-05 23.3 6.8 3.5e-05 23.3 4.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR21211.1 - 0.0027 17.4 8.7 0.0062 16.3 6.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR21211.1 - 0.0033 17.0 11.2 0.0075 15.9 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CAR21211.1 - 0.0034 16.6 3.0 0.0034 16.6 2.1 2.1 3 0 0 3 3 3 1 Rtf2 RING-finger SET_assoc PF11767.3 CAR21211.1 - 0.0088 15.3 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_6 PF14259.1 CAR21211.1 - 0.011 15.7 0.1 0.045 13.7 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 CAR21211.1 - 0.042 13.5 4.2 0.11 12.2 2.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 CAR21211.1 - 0.47 10.2 9.2 1.1 9.0 6.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAR21211.1 - 1.3 8.9 10.7 6.3 6.7 7.4 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING U1snRNP70_N PF12220.3 CAR21212.1 - 4.6e-20 71.7 0.2 9e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 CAR21212.1 - 4.1e-15 55.1 0.0 7.2e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21212.1 - 5.3e-13 48.7 0.0 8.8e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR21212.1 - 1.4e-05 24.8 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3906 PF13046.1 CAR21212.1 - 0.11 12.0 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) TFIIE-A_C-term PF11521.3 CAR21212.1 - 0.13 12.1 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF619 PF04768.8 CAR21213.1 - 4.4e-51 172.6 0.1 9.5e-51 171.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CAR21213.1 - 1.5e-30 105.9 0.0 3.1e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CAR21213.1 - 7.2e-18 64.9 0.0 1.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 CAR21213.1 - 1.6e-09 37.8 0.1 7.7e-09 35.6 0.0 2.2 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 CAR21213.1 - 0.026 14.4 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus P16-Arc PF04699.9 CAR21214.1 - 7.9e-54 181.8 0.0 8.8e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2313 PF10076.4 CAR21214.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) Ran_BP1 PF00638.13 CAR21215.1 - 2.2e-33 114.9 0.0 4.5e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain MIP-T3 PF10243.4 CAR21215.1 - 2.1 6.6 38.6 3 6.2 26.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 CAR21215.1 - 3.2 5.5 27.3 0.04 11.8 13.0 1.8 2 0 0 2 2 2 0 Nop14-like family Methyltransf_31 PF13847.1 CAR21216.1 - 1.2e-25 89.8 0.0 1.9e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR21216.1 - 2.2e-17 63.6 0.0 5e-17 62.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR21216.1 - 2.6e-07 31.0 0.0 4.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CAR21216.1 - 5.5e-06 26.1 0.0 7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR21216.1 - 1.2e-05 25.7 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR21216.1 - 7.1e-05 23.1 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR21216.1 - 0.00023 20.6 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CAR21216.1 - 0.00043 20.3 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CAR21216.1 - 0.0011 18.3 0.1 0.0026 17.0 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 AdoMet_MTase PF07757.8 CAR21216.1 - 0.0013 18.8 0.0 0.0032 17.5 0.0 1.6 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 CAR21216.1 - 0.002 17.8 0.0 0.0039 16.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 CAR21216.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 CAR21216.1 - 0.022 13.9 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Fis1_TPR_C PF14853.1 CAR21217.1 - 8.9e-25 86.3 0.1 1.3e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CAR21217.1 - 2.2e-15 55.6 0.0 4e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat QLQ PF08880.6 CAR21217.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 QLQ TPR_14 PF13428.1 CAR21217.1 - 0.11 13.1 0.0 0.37 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.10 CAR21218.1 - 2.5e-215 716.1 0.0 3.8e-215 715.5 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CAR21218.1 - 2.7e-23 81.5 0.0 6.6e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CAR21218.1 - 3.2e-16 59.5 0.0 1.2e-15 57.7 0.0 2.1 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 CAR21218.1 - 0.001 17.2 0.0 0.0018 16.4 0.0 1.4 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase LCCL PF03815.14 CAR21219.1 - 4.6e-11 42.5 0.1 1e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 LCCL domain Sec6 PF06046.8 CAR21220.1 - 4e-163 543.5 9.3 4e-163 543.5 6.5 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 CAR21220.1 - 1.5 7.5 19.2 0.16 10.7 2.7 3.1 3 0 0 3 3 3 0 Vps53-like, N-terminal Tctex-1 PF03645.8 CAR21221.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 CAR21222.1 - 6e-14 52.0 2.9 6e-14 52.0 2.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 CAR21222.1 - 0.013 15.3 0.1 0.013 15.3 0.1 2.0 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF2207 PF09972.4 CAR21222.1 - 0.24 9.9 1.9 0.31 9.5 1.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Aldedh PF00171.17 CAR21223.1 - 6.6e-184 611.5 0.0 7.4e-184 611.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CAR21223.1 - 0.0029 16.3 0.0 0.0053 15.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ribosomal_S24e PF01282.14 CAR21224.1 - 1.6e-34 117.5 0.1 2.5e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e SeleniumBinding PF11524.3 CAR21224.1 - 0.018 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Selenium binding protein RAMPs PF03787.10 CAR21224.1 - 0.074 12.8 0.6 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 RAMP superfamily Yos1 PF08571.5 CAR21225.1 - 2.7e-31 107.4 2.1 3.1e-31 107.3 1.5 1.0 1 0 0 1 1 1 1 Yos1-like EPO_TPO PF00758.13 CAR21225.1 - 0.085 12.4 0.3 0.11 12.1 0.2 1.1 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Y_phosphatase PF00102.22 CAR21226.1 - 7.1e-48 162.9 0.2 1.3e-47 162.0 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CAR21226.1 - 7e-09 36.0 0.0 2.8e-07 30.8 0.0 2.6 2 1 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 CAR21226.1 - 0.0053 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CAR21226.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family MAM33 PF02330.11 CAR21227.1 - 7.2e-47 159.7 4.3 8.5e-47 159.5 3.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cons_hypoth95 PF03602.10 CAR21227.1 - 0.0038 16.6 0.1 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 NAD_binding_2 PF03446.10 CAR21227.1 - 0.022 14.6 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PPR_2 PF13041.1 CAR21228.1 - 4.6e-24 84.1 0.0 1.5e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR_1 PF12854.2 CAR21228.1 - 0.00027 20.3 0.2 0.33 10.4 0.0 3.3 3 0 0 3 3 3 2 PPR repeat DUF2089 PF09862.4 CAR21229.1 - 0.0062 16.3 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) TPR_2 PF07719.12 CAR21229.1 - 0.017 15.0 0.2 0.51 10.3 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat ApoLp-III PF07464.6 CAR21229.1 - 0.074 13.0 0.9 0.12 12.3 0.3 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Peptidase_M24 PF00557.19 CAR21230.1 - 4.9e-50 169.9 0.0 7.1e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CAR21230.1 - 1.6e-31 108.4 0.0 3.3e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HORMA PF02301.13 CAR21231.1 - 1.2e-48 165.3 0.2 8.8e-48 162.5 0.0 2.3 2 1 0 2 2 2 1 HORMA domain PHD_2 PF13831.1 CAR21231.1 - 0.039 13.2 7.4 0.081 12.2 5.1 1.6 1 0 0 1 1 1 0 PHD-finger IRK_N PF08466.5 CAR21232.1 - 1.3 8.9 3.9 0.49 10.3 0.5 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal APH PF01636.18 CAR21233.1 - 5.4e-09 36.1 0.0 1.2e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR21233.1 - 0.0082 15.2 0.0 5.1 6.1 0.0 2.8 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family POPLD PF08170.7 CAR21233.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 POPLD (NUC188) domain 2-Hacid_dh_C PF02826.14 CAR21234.1 - 1.4e-52 177.4 0.0 2.6e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR21234.1 - 5.2e-37 126.2 0.1 6.8e-37 125.9 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 CAR21234.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 CAR21234.1 - 0.00028 20.7 0.5 0.00061 19.6 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 CAR21234.1 - 0.00038 19.8 0.1 0.0028 17.0 0.0 2.4 2 0 0 2 2 2 1 ACT domain Acetyltransf_1 PF00583.19 CAR21234.1 - 0.021 14.8 0.0 0.11 12.5 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family PC_rep PF01851.17 CAR21235.1 - 3.3e-42 140.3 16.5 9.1e-06 25.6 0.1 9.7 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CAR21235.1 - 1.9e-16 60.1 4.5 9.9e-14 51.3 0.1 4.0 2 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 CAR21235.1 - 5.2e-09 36.3 2.9 0.0095 16.4 0.0 4.9 4 2 1 5 5 5 3 HEAT-like repeat HEAT PF02985.17 CAR21235.1 - 5.6e-07 29.1 1.8 0.53 10.5 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat RICTOR_V PF14668.1 CAR21235.1 - 0.036 13.9 0.2 1.9 8.5 0.0 3.6 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Apc3 PF12895.2 CAR21235.1 - 0.059 13.5 0.6 0.37 10.9 0.4 2.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4355 PF14265.1 CAR21235.1 - 4.7 7.1 18.7 0.45 10.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) BING4CT PF08149.6 CAR21236.1 - 1.3e-36 123.9 0.0 1.6e-34 117.2 0.0 3.4 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 CAR21236.1 - 2e-07 30.6 0.0 3.6e-05 23.4 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat DHO_dh PF01180.16 CAR21237.1 - 2.1e-97 325.6 0.1 2.5e-97 325.4 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CAR21237.1 - 0.0075 15.1 0.0 0.54 9.0 0.0 2.4 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.12 CAR21237.1 - 0.0094 15.2 0.1 3.9 6.6 0.0 2.2 2 0 0 2 2 2 2 PcrB family DUF3372 PF11852.3 CAR21237.1 - 0.047 12.8 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) GET2 PF08690.5 CAR21238.1 - 9.7e-87 291.0 0.2 1.1e-86 290.8 0.1 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 Pex19 PF04614.7 CAR21238.1 - 0.0047 16.5 3.8 0.0063 16.1 2.7 1.2 1 0 0 1 1 1 1 Pex19 protein family DUF1631 PF07793.6 CAR21238.1 - 0.36 8.9 7.5 0.49 8.4 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Coatomer_E PF04733.9 CAR21239.1 - 1.3e-14 54.1 8.7 1.7e-14 53.6 6.1 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 CAR21239.1 - 1.7e-05 25.0 8.0 0.041 14.2 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR21239.1 - 0.0021 18.6 0.7 12 6.7 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR21239.1 - 0.021 14.7 8.1 5.1 7.2 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 CAR21239.1 - 0.022 14.8 2.3 0.24 11.5 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAR21239.1 - 0.048 13.3 2.9 1.2 8.8 0.2 3.3 3 0 0 3 3 3 0 TPR repeat Apc3 PF12895.2 CAR21239.1 - 0.083 13.0 0.3 0.083 13.0 0.2 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CAR21239.1 - 0.1 12.2 1.9 4.4 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAR21239.1 - 0.23 12.2 4.2 9.9 7.1 0.1 3.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAR21239.1 - 0.36 10.7 2.9 3.1 7.7 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1689 PF07954.6 CAR21240.1 - 2.6e-48 163.7 0.1 3.4e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) Peptidase_C69 PF03577.10 CAR21240.1 - 0.046 12.6 0.4 0.094 11.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family C69 tRNA-synt_2b PF00587.20 CAR21241.1 - 2.8e-45 153.9 1.2 5.9e-45 152.9 0.5 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR21241.1 - 4.3e-19 68.2 1.3 1e-18 67.0 0.9 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 CAR21241.1 - 3.5e-14 52.3 0.0 7.2e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 CAR21241.1 - 2e-11 43.5 0.0 4.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain zf-CCHC PF00098.18 CAR21242.1 - 5.8e-08 32.2 42.6 4e-05 23.3 1.9 4.8 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_2 PF13696.1 CAR21242.1 - 0.36 10.3 18.8 2.3 7.8 1.1 4.5 2 1 2 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.1 CAR21242.1 - 2.9 7.6 33.8 0.81 9.4 2.2 5.4 4 1 1 5 5 5 0 Zinc knuckle Pmp3 PF01679.12 CAR21243.1 - 5.9e-20 70.7 4.0 7.9e-20 70.3 2.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPF0029 PF01205.14 CAR21244.1 - 2.3e-31 107.7 0.0 2.9e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 FAD-oxidase_C PF02913.14 CAR21245.1 - 3.4e-57 193.6 0.0 4.9e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAR21245.1 - 3.6e-37 126.9 0.1 6.5e-37 126.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Imm3 PF14425.1 CAR21245.1 - 0.063 13.2 0.1 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Immunity protein Imm3 HIT PF01230.18 CAR21246.1 - 1.1e-22 80.3 0.1 1.5e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CAR21246.1 - 4.3e-07 30.1 0.1 7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.24 CAR21247.1 - 5.3e-98 324.3 0.0 6.1e-48 162.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CAR21247.1 - 3.7e-18 65.2 2.8 7.4e-18 64.2 0.8 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CAR21247.1 - 4.6e-14 52.6 0.0 1.5e-07 31.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CAR21247.1 - 2.2e-13 49.7 0.0 2.1e-05 23.7 0.0 3.0 3 1 1 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CAR21247.1 - 1.2e-12 47.7 0.4 3.9e-06 26.6 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR21247.1 - 3.9e-12 46.5 0.1 0.0005 20.0 0.0 4.0 3 1 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.1 CAR21247.1 - 1.7e-11 44.1 0.0 7.8e-06 25.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CAR21247.1 - 2.4e-11 44.5 0.1 0.0007 20.4 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CAR21247.1 - 2.8e-10 40.4 4.5 0.00099 19.2 0.1 4.5 3 2 0 3 3 3 2 AAA domain TIP49 PF06068.8 CAR21247.1 - 2.6e-09 36.2 0.0 0.0012 17.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CAR21247.1 - 2.1e-08 34.1 0.0 0.0042 16.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 CAR21247.1 - 2.2e-08 33.5 0.0 6.5e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.12 CAR21247.1 - 1.2e-07 31.2 1.1 0.0073 15.7 0.0 3.1 4 0 0 4 4 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 CAR21247.1 - 1.9e-07 31.1 0.0 0.011 15.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 CAR21247.1 - 2.3e-07 30.4 0.8 0.025 14.3 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 CAR21247.1 - 3.7e-07 29.5 0.5 0.03 13.5 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CAR21247.1 - 3.8e-07 29.4 0.1 0.012 14.7 0.0 3.1 3 1 0 3 3 3 2 Zeta toxin AAA_25 PF13481.1 CAR21247.1 - 5.6e-07 29.1 6.8 0.028 13.8 0.1 4.3 2 2 2 4 4 4 2 AAA domain AAA_24 PF13479.1 CAR21247.1 - 3.3e-06 26.8 0.1 0.11 12.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 CAR21247.1 - 5e-06 25.8 4.3 0.25 10.4 0.0 3.9 2 2 2 4 4 4 2 KaiC AAA_18 PF13238.1 CAR21247.1 - 6.1e-06 26.5 0.1 0.19 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 CAR21247.1 - 6.9e-06 26.4 0.1 0.046 14.0 0.0 4.0 3 1 0 3 3 3 1 ABC transporter ResIII PF04851.10 CAR21247.1 - 7e-06 25.9 0.0 0.0068 16.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CAR21247.1 - 7.3e-06 26.0 0.5 0.2 11.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CAR21247.1 - 2e-05 24.0 0.1 0.22 10.9 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain Vps4_C PF09336.5 CAR21247.1 - 2.1e-05 24.3 0.3 0.00081 19.2 0.0 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.12 CAR21247.1 - 3e-05 23.0 0.1 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.11 CAR21247.1 - 3.9e-05 22.9 0.6 0.12 11.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.8 CAR21247.1 - 5.6e-05 22.1 0.0 0.068 12.0 0.0 2.9 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA_11 PF13086.1 CAR21247.1 - 7.7e-05 22.3 0.0 0.5 9.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 CAR21247.1 - 8.8e-05 22.5 0.0 0.38 10.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 CAR21247.1 - 0.00013 21.5 0.0 0.67 9.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 CAR21247.1 - 0.00013 21.6 0.2 0.32 10.6 0.0 3.3 4 0 0 4 4 3 1 Bacterial dnaA protein Arch_ATPase PF01637.13 CAR21247.1 - 0.00017 21.4 1.1 0.5 10.0 0.0 3.9 3 2 2 5 5 3 1 Archaeal ATPase NACHT PF05729.7 CAR21247.1 - 0.00028 20.6 0.1 1.6 8.3 0.0 3.5 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 CAR21247.1 - 0.00047 19.2 0.0 0.69 8.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CAR21247.1 - 0.00066 19.3 0.0 1.6 8.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CAR21247.1 - 0.0057 15.5 0.1 1.8 7.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 CAR21247.1 - 0.0073 16.0 1.6 3.3 7.3 0.0 4.4 4 0 0 4 4 4 0 NTPase IPT PF01745.11 CAR21247.1 - 0.015 14.4 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 CAR21247.1 - 0.018 14.0 0.2 1.6 7.6 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 CAR21247.1 - 0.026 13.4 0.0 3.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.7 CAR21247.1 - 0.032 13.6 0.8 6.3 6.2 0.1 3.7 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) SKI PF01202.17 CAR21247.1 - 0.045 13.6 0.0 4.7 7.0 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 CAR21247.1 - 0.064 12.8 0.1 6.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Cyclin_N PF00134.18 CAR21248.1 - 1.1e-15 57.2 0.1 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CAR21248.1 - 1.9e-08 34.8 0.1 3.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin Na_Ca_ex PF01699.19 CAR21249.1 - 1.1e-50 170.9 27.8 1.1e-25 89.8 8.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1109 PF06532.6 CAR21249.1 - 0.019 14.3 4.4 0.49 9.7 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1109) ARS2 PF04959.8 CAR21251.1 - 0.054 13.6 0.8 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Ndc80_HEC PF03801.8 CAR21251.1 - 0.071 12.5 1.0 0.13 11.7 0.6 1.5 1 1 0 1 1 1 0 HEC/Ndc80p family Ribosomal_60s PF00428.14 CAR21252.1 - 3.6e-24 84.9 13.0 4.2e-24 84.7 9.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Jun PF03957.8 CAR21252.1 - 0.14 11.8 3.2 0.16 11.6 2.2 1.1 1 0 0 1 1 1 0 Jun-like transcription factor Glyco_hydro_63 PF03200.11 CAR21254.1 - 3.4e-06 25.2 0.3 3.4e-06 25.2 0.2 4.2 4 2 0 4 4 4 2 Mannosyl oligosaccharide glucosidase Ribosomal_S6 PF01250.12 CAR21254.1 - 0.049 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S6 V-SNARE_C PF12352.3 CAR21255.1 - 5.9e-20 71.1 1.8 5.9e-20 71.1 1.3 2.0 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CAR21255.1 - 2.1e-19 69.4 1.7 2.1e-19 69.4 1.2 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 CAR21255.1 - 0.00046 19.8 4.0 0.00047 19.8 0.4 2.4 2 1 1 3 3 3 1 Sec20 Toxin_52 PF15605.1 CAR21255.1 - 0.015 15.1 2.1 0.028 14.3 0.4 2.1 2 0 0 2 2 2 0 Putative toxin 52 Urb2 PF10441.4 CAR21255.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Urb2/Npa2 family AIG1 PF04548.11 CAR21255.1 - 0.019 14.0 2.3 2 7.4 0.0 2.3 1 1 1 2 2 2 0 AIG1 family Flu_NS2 PF00601.14 CAR21255.1 - 0.052 13.7 0.2 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Snapin_Pallidin PF14712.1 CAR21255.1 - 0.067 13.4 4.6 0.12 12.6 1.6 2.3 2 0 0 2 2 2 0 Snapin/Pallidin YqjK PF13997.1 CAR21255.1 - 0.17 12.0 1.5 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 YqjK-like protein Use1 PF09753.4 CAR21255.1 - 0.7 9.2 4.9 3.4 7.0 3.4 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Nsp1_C PF05064.8 CAR21255.1 - 1.2 8.8 6.9 0.46 10.1 1.0 2.6 2 1 1 3 3 3 0 Nsp1-like C-terminal region Fer2 PF00111.22 CAR21256.1 - 2.9e-14 52.5 0.5 3.7e-14 52.2 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 CAR21256.1 - 0.1 12.3 0.9 0.35 10.7 0.6 1.9 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain LysM PF01476.15 CAR21256.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 LysM domain SAGA-Tad1 PF12767.2 CAR21258.1 - 2e-75 253.7 0.3 2.7e-75 253.2 0.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 CAR21258.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BBP1_C PF15272.1 CAR21259.1 - 2.8e-57 193.4 22.6 2.8e-57 193.4 15.6 1.5 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.1 CAR21259.1 - 7e-43 146.4 3.4 7e-43 146.4 2.3 2.2 2 0 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein Endotoxin_N PF03945.9 CAR21259.1 - 0.082 12.2 2.1 0.1 12.0 0.6 1.7 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain Pox_A_type_inc PF04508.7 CAR21259.1 - 0.48 10.3 6.3 1.1 9.1 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Syntaxin-6_N PF09177.6 CAR21259.1 - 1.7 9.1 9.1 0.34 11.3 2.8 2.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.10 CAR21259.1 - 1.7 8.2 11.6 0.046 13.2 0.7 3.0 2 1 1 3 3 3 0 Septum formation initiator Cyclin_N PF00134.18 CAR21261.1 - 5.6e-38 129.3 0.0 9.2e-38 128.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Rot1 PF10681.4 CAR21262.1 - 3.1e-92 307.7 0.2 3.5e-92 307.5 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VHS PF00790.14 CAR21263.1 - 1.1e-38 132.1 0.0 2.1e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 CAR21263.1 - 1.1e-18 66.8 2.8 1.1e-18 66.8 1.9 2.2 2 0 0 2 2 2 1 FYVE zinc finger UIM PF02809.15 CAR21263.1 - 0.00053 19.3 20.6 0.11 12.1 1.0 5.2 4 0 0 4 4 4 2 Ubiquitin interaction motif BLVR PF06375.6 CAR21263.1 - 5.9 6.6 16.7 5.5 6.8 4.3 3.3 3 1 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) zf-AN1 PF01428.11 CAR21263.1 - 9.5 6.1 13.5 0.47 10.3 5.3 1.9 2 0 0 2 2 2 0 AN1-like Zinc finger XPA_C PF05181.7 CAR21264.1 - 8.1e-27 92.5 0.2 1.9e-26 91.3 0.1 1.7 1 0 0 1 1 1 1 XPA protein C-terminus vMSA PF00695.14 CAR21264.1 - 0.099 11.8 1.1 0.15 11.2 0.1 1.7 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Fer4_2 PF12797.2 CAR21264.1 - 9.4 6.3 7.2 8.6 6.5 0.2 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Autophagy_N PF03986.8 CAR21265.1 - 5.2e-44 149.5 1.1 5.2e-44 149.5 0.8 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CAR21265.1 - 1.3e-22 79.7 2.6 2.2e-22 78.9 0.3 2.5 4 0 0 4 4 4 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CAR21265.1 - 2.1e-14 52.2 0.5 3.6e-14 51.5 0.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal LCAT PF02450.10 CAR21266.1 - 6.7e-127 423.6 0.1 8.3e-127 423.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 CAR21266.1 - 0.0013 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 CAR21266.1 - 0.026 13.4 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Whi5 PF08528.6 CAR21267.1 - 1.7e-05 24.3 1.1 2.7e-05 23.6 0.7 1.3 1 0 0 1 1 1 1 Whi5 like ERG2_Sigma1R PF04622.7 CAR21268.1 - 7.8e-79 263.9 0.3 8.5e-79 263.7 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Med9 PF07544.8 CAR21269.1 - 2.1e-25 88.2 1.6 2.8e-25 87.8 1.1 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Leu_zip PF15294.1 CAR21269.1 - 0.014 14.4 0.4 0.014 14.4 0.3 1.2 1 0 0 1 1 1 0 Leucine zipper TelA PF05816.6 CAR21269.1 - 0.023 13.4 0.1 0.029 13.0 0.1 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) UBN2 PF14223.1 CAR21269.1 - 0.024 14.4 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Uso1_p115_C PF04871.8 CAR21269.1 - 0.027 14.3 0.5 0.035 14.0 0.3 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spore_III_AB PF09548.5 CAR21269.1 - 0.029 14.1 0.1 0.036 13.8 0.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF1409 PF07197.7 CAR21269.1 - 0.033 14.2 4.2 0.089 12.8 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1409) AAA_13 PF13166.1 CAR21269.1 - 0.034 12.6 0.3 0.037 12.4 0.2 1.0 1 0 0 1 1 1 0 AAA domain FH2 PF02181.18 CAR21269.1 - 0.043 12.6 0.2 0.048 12.5 0.1 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF3595 PF12166.3 CAR21269.1 - 0.05 12.4 0.4 0.059 12.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) ATG16 PF08614.6 CAR21269.1 - 0.071 12.9 2.4 0.078 12.7 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Antigen_Bd37 PF11641.3 CAR21269.1 - 0.082 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein UBN2_2 PF14227.1 CAR21269.1 - 0.091 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Fib_alpha PF08702.5 CAR21269.1 - 0.1 12.6 0.9 0.39 10.8 0.6 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MerR-DNA-bind PF09278.6 CAR21269.1 - 0.16 12.4 6.6 0.25 11.7 2.6 2.3 2 1 0 2 2 2 0 MerR, DNA binding IncA PF04156.9 CAR21269.1 - 0.37 10.3 4.0 0.39 10.2 2.8 1.1 1 0 0 1 1 1 0 IncA protein Porin_3 PF01459.17 CAR21270.1 - 3.4e-82 275.7 0.1 4e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Inp1 PF12634.2 CAR21271.1 - 6.2e-45 152.4 0.3 1.2e-44 151.4 0.2 1.5 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 PFK PF00365.15 CAR21272.1 - 4.3e-166 550.8 1.7 9.8e-125 415.1 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 CAR21272.1 - 0.017 15.7 0.0 0.049 14.2 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase-like domain T4SS PF07996.6 CAR21272.1 - 0.023 14.5 0.0 0.71 9.7 0.0 2.9 3 0 0 3 3 3 0 Type IV secretion system proteins Glyoxalase PF00903.20 CAR21273.1 - 4.8e-36 123.5 0.2 2.3e-20 72.8 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CAR21273.1 - 1.4e-30 106.0 0.0 3.4e-14 53.3 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CAR21273.1 - 7.2e-18 64.5 0.0 9.8e-09 35.2 0.0 3.3 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CAR21273.1 - 0.00013 21.9 0.0 0.0022 17.9 0.0 2.6 1 1 1 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.1 CAR21273.1 - 0.00087 18.9 0.2 0.084 12.5 0.0 2.7 3 0 0 3 3 3 1 CppA N-terminal LAGLIDADG_2 PF03161.8 CAR21273.1 - 0.062 13.1 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family HA2 PF04408.18 CAR21274.1 - 1.7e-18 66.4 0.0 8.4e-18 64.2 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR21274.1 - 7.3e-17 61.2 0.0 1.9e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAR21274.1 - 7e-14 51.4 0.0 2e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR21274.1 - 4.2e-07 29.6 1.3 5.7e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR21274.1 - 6.7e-06 26.2 0.1 2.4e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CAR21274.1 - 0.00095 18.1 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 CAR21274.1 - 0.026 14.2 0.1 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 CAR21274.1 - 0.044 14.0 2.9 0.066 13.5 0.0 2.7 3 1 0 3 3 3 0 ABC transporter AAA_14 PF13173.1 CAR21274.1 - 0.071 13.0 2.7 0.41 10.5 0.1 3.1 2 1 0 2 2 2 0 AAA domain PRK PF00485.13 CAR21275.1 - 1.5e-61 207.3 0.0 2.1e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 CAR21275.1 - 9.5e-36 122.9 0.0 1.6e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.1 CAR21275.1 - 2e-06 28.1 0.0 5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR21275.1 - 7.2e-06 26.8 0.0 1.8e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR21275.1 - 0.00051 19.1 0.0 0.00092 18.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.7 CAR21275.1 - 0.00081 19.0 0.0 0.002 17.7 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 CAR21275.1 - 0.0074 16.1 0.0 0.026 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 CAR21275.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain SPX PF03105.14 CAR21276.1 - 1.7e-44 152.6 2.1 1.7e-44 152.6 1.5 2.1 2 1 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 CAR21276.1 - 6.2e-22 78.1 45.5 8.1e-22 77.7 31.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CAR21276.1 - 1.2e-14 53.6 44.6 8.1e-11 41.0 15.8 2.1 1 1 1 2 2 2 2 Citrate transporter Nucleoplasmin PF03066.10 CAR21276.1 - 0.046 13.2 2.6 0.082 12.4 1.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 CAR21276.1 - 0.087 12.9 2.4 0.18 11.9 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 CAR21276.1 - 0.11 12.7 5.2 0.28 11.5 3.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3245 PF11595.3 CAR21276.1 - 0.24 11.6 6.6 0.044 14.0 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Sigma70_ner PF04546.8 CAR21276.1 - 0.75 9.3 3.5 1.6 8.2 2.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF373 PF04123.8 CAR21276.1 - 1.3 7.9 19.5 0.038 12.9 5.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) NOA36 PF06524.7 CAR21276.1 - 7.9 5.6 6.1 14 4.8 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1708 PF08101.6 CAR21278.1 - 4e-57 193.9 0.2 6.6e-57 193.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Kelch_3 PF13415.1 CAR21278.1 - 2.7 8.2 4.3 2.6 8.2 0.5 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Dus PF01207.12 CAR21279.1 - 2.7e-53 180.8 0.0 1.3e-52 178.5 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 CAR21279.1 - 0.055 12.3 0.1 0.1 11.3 0.0 1.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase COX5A PF02284.11 CAR21279.1 - 0.096 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va ACC_central PF08326.7 CAR21280.1 - 1.4e-264 879.6 0.8 1.9e-264 879.1 0.6 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CAR21280.1 - 7.7e-179 595.1 0.0 1.1e-178 594.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CAR21280.1 - 3.8e-51 173.3 0.0 8.2e-51 172.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CAR21280.1 - 5.3e-25 87.6 0.0 1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAR21280.1 - 4.7e-20 71.5 0.0 2.2e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CAR21280.1 - 1.3e-19 69.5 0.1 4e-19 68.0 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CAR21280.1 - 3.9e-10 39.7 0.0 1.2e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAR21280.1 - 1e-08 34.3 0.0 0.0018 17.0 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CAR21280.1 - 6.8e-06 25.6 0.1 0.013 15.1 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CAR21280.1 - 0.00025 20.4 0.0 0.00055 19.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CAR21280.1 - 0.0063 16.3 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.1 CAR21280.1 - 0.016 14.9 0.0 0.056 13.1 0.0 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATP-grasp PF02222.17 CAR21280.1 - 0.019 14.2 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain HlyD_2 PF12700.2 CAR21280.1 - 0.077 12.1 0.0 4.1 6.4 0.0 2.9 2 1 1 3 3 3 0 HlyD family secretion protein zf-DBF PF07535.7 CAR21280.1 - 1.2 8.9 2.5 26 4.5 0.0 3.5 4 0 0 4 4 3 0 DBF zinc finger Tim17 PF02466.14 CAR21281.1 - 4.9e-30 104.1 1.9 6.2e-30 103.8 1.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_S8 PF00082.17 CAR21282.1 - 8.8e-43 146.4 0.5 1.3e-42 145.8 0.4 1.2 1 0 0 1 1 1 1 Subtilase family HIG_1_N PF04588.8 CAR21283.1 - 8e-05 22.3 1.9 0.00017 21.2 1.3 1.6 1 1 0 1 1 1 1 Hypoxia induced protein conserved region Ribosomal_L19 PF01245.15 CAR21284.1 - 2.3e-12 46.6 0.1 3.4e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 WBS_methylT PF12589.3 CAR21285.1 - 3.4e-18 65.9 7.2 7.1e-18 64.8 5.0 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CAR21285.1 - 4.4e-13 49.5 0.0 1e-12 48.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR21285.1 - 9.1e-09 35.5 0.1 4.4e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR21285.1 - 2.1e-08 34.0 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR21285.1 - 2e-07 30.7 0.0 4.1e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR21285.1 - 3.5e-06 27.3 0.1 1.3e-05 25.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR21285.1 - 0.00012 22.6 0.0 0.00036 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CAR21285.1 - 0.00022 20.8 0.0 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CAR21285.1 - 0.00048 20.1 0.0 0.0015 18.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CAR21285.1 - 0.00053 19.1 0.3 0.0078 15.3 0.0 2.5 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 CAR21285.1 - 0.0036 17.4 0.0 0.0085 16.2 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PrmA PF06325.8 CAR21285.1 - 0.0069 15.5 1.1 0.014 14.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 CAR21285.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW bHLH-MYC_N PF14215.1 CAR21285.1 - 0.045 13.9 0.3 1.3 9.1 0.0 2.6 2 1 1 3 3 3 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal His_binding PF02098.11 CAR21285.1 - 0.25 11.1 3.2 0.13 12.0 0.6 1.6 2 0 0 2 2 2 0 Tick histamine binding protein MBOAT PF03062.14 CAR21286.1 - 1.3e-60 205.2 42.5 5e-60 203.3 29.4 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CAR21286.1 - 0.00034 20.6 6.3 0.0011 18.9 4.4 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_M76 PF09768.4 CAR21287.1 - 2.4e-76 255.0 2.0 2.9e-76 254.7 1.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family Ank_5 PF13857.1 CAR21288.1 - 9.6e-15 54.2 0.1 2.4e-09 37.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR21288.1 - 8.1e-12 45.3 0.0 1.6e-10 41.1 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAR21288.1 - 3.9e-10 39.0 0.1 4.3e-06 26.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CAR21288.1 - 1.3e-09 37.3 0.1 3.2e-05 23.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CAR21288.1 - 1.3e-07 31.9 0.0 1.8e-06 28.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF1682 PF07946.9 CAR21289.1 - 7.4e-84 281.3 5.3 8.6e-84 281.1 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) GBP_C PF02841.9 CAR21289.1 - 0.034 13.3 12.3 0.052 12.7 8.5 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RDV-p3 PF09231.5 CAR21289.1 - 0.062 10.7 0.2 0.11 9.8 0.2 1.3 1 0 0 1 1 1 0 Rice dwarf virus p3 Ribosomal_L9_N PF01281.14 CAR21290.1 - 0.00023 20.3 0.0 0.0013 17.9 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Acyl-thio_N PF12590.3 CAR21290.1 - 0.089 13.2 0.3 0.14 12.6 0.2 1.3 1 0 0 1 1 1 0 Acyl-ATP thioesterase DUF3987 PF13148.1 CAR21290.1 - 0.23 9.9 3.6 0.3 9.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ATP-synt_B PF00430.13 CAR21290.1 - 4.7 7.0 11.2 3 7.6 6.5 1.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) SWIB PF02201.13 CAR21291.1 - 0.055 13.1 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 SWIB/MDM2 domain Thr_synth_N PF14821.1 CAR21292.1 - 2.2e-29 101.3 0.1 7.3e-29 99.6 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 CAR21292.1 - 1.1e-18 67.5 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.27 CAR21293.1 - 1.7e-65 214.7 14.3 8.4e-13 47.6 0.1 13.5 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 CAR21293.1 - 1.8e-28 98.6 0.0 2.7e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 CAR21293.1 - 8.6e-08 32.1 0.8 0.0011 18.7 0.1 4.8 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CAR21293.1 - 2.7e-07 29.1 4.6 0.14 10.2 0.0 4.9 2 1 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CAR21293.1 - 0.00012 21.6 0.2 0.018 14.5 0.1 2.9 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 CAR21293.1 - 0.0041 15.9 0.2 23 3.5 0.0 4.1 2 1 2 4 4 4 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 CAR21293.1 - 0.01 14.1 0.1 1.1 7.5 0.0 3.2 3 0 0 3 3 3 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 CAR21293.1 - 0.012 14.9 1.1 2.5 7.4 0.2 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature RAB3GAP2_N PF14655.1 CAR21293.1 - 0.025 13.6 0.0 1.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Utp14 PF04615.8 CAR21294.1 - 0.017 13.2 22.7 0.019 13.1 15.7 1.0 1 0 0 1 1 1 0 Utp14 protein MPP6 PF10175.4 CAR21294.1 - 0.071 13.4 0.3 0.071 13.4 0.2 2.5 2 1 0 2 2 2 0 M-phase phosphoprotein 6 UPF0029 PF01205.14 CAR21295.1 - 3.2e-26 91.1 0.0 5.1e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CAR21295.1 - 4.4e-12 45.8 0.1 7.6e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 RWD domain Ytp1 PF10355.4 CAR21296.1 - 2.7e-105 351.4 10.2 2.7e-105 351.4 7.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CAR21296.1 - 1.8e-11 43.5 1.5 1.8e-11 43.5 1.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) FMN_red PF03358.10 CAR21297.1 - 9.7e-29 99.8 0.0 1.3e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CAR21297.1 - 1.1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold G10 PF01125.12 CAR21298.1 - 4e-59 198.3 5.5 4.5e-59 198.1 3.8 1.0 1 0 0 1 1 1 1 G10 protein zf-RING_5 PF14634.1 CAR21298.1 - 7.1 6.4 13.4 2.4 7.9 4.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Fork_head PF00250.13 CAR21299.1 - 1.3e-32 111.6 0.1 2.4e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Fork head domain zf-C3HC4 PF00097.20 CAR21300.1 - 1.6e-10 40.4 10.3 1.6e-10 40.4 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR21300.1 - 7.9e-09 35.0 10.3 7.9e-08 31.8 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR21300.1 - 8.7e-09 35.2 14.6 2.5e-08 33.7 7.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR21300.1 - 2.4e-07 30.3 13.3 1.3e-06 27.9 6.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CAR21300.1 - 2.7e-07 30.3 14.7 1e-06 28.4 6.7 2.4 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.22 CAR21300.1 - 6.7e-07 28.6 0.0 1.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.1 CAR21300.1 - 1.1e-05 25.0 7.7 1.1e-05 25.0 5.3 2.7 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAR21300.1 - 1.3e-05 25.0 10.9 1.3e-05 25.0 7.6 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CAR21300.1 - 3e-05 23.7 5.1 3e-05 23.7 3.5 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CAR21300.1 - 3.9e-05 23.6 5.6 0.00086 19.3 2.1 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 CAR21300.1 - 0.0023 17.8 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain GAGA PF09237.6 CAR21300.1 - 0.01 15.4 1.4 0.32 10.6 0.1 3.0 2 0 0 2 2 2 0 GAGA factor zf-RING_4 PF14570.1 CAR21300.1 - 0.044 13.3 6.5 0.11 12.1 1.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CAR21300.1 - 0.28 10.7 10.3 0.64 9.5 4.5 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 CAR21300.1 - 0.86 9.1 5.9 12 5.4 0.1 3.6 4 0 0 4 4 4 0 Rad50 zinc hook motif FYVE PF01363.16 CAR21300.1 - 2.4 8.1 7.5 9.4 6.2 0.0 2.7 2 1 0 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.1 CAR21300.1 - 6.8 6.3 10.9 11 5.6 4.4 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.27 CAR21301.1 - 5.2e-08 32.4 0.1 0.00022 20.9 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2963 PF11178.3 CAR21301.1 - 0.097 12.1 0.1 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Phos_pyr_kin PF08543.7 CAR21302.1 - 1.2e-12 47.5 0.0 1.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CAR21302.1 - 1e-07 31.4 0.0 3e-06 26.5 0.0 2.4 2 1 1 3 3 3 1 pfkB family carbohydrate kinase Adeno_GP19K PF04881.8 CAR21302.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus GP19K Lipase_3 PF01764.20 CAR21303.1 - 1.9e-09 37.2 0.0 3.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CAR21303.1 - 0.0058 16.4 0.0 0.047 13.4 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 CAR21303.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.2 CAR21303.1 - 0.042 13.7 0.1 0.075 12.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 CAR21304.1 - 8.5e-06 25.5 4.8 2.2e-05 24.2 3.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1864 PF08933.6 CAR21304.1 - 0.017 13.6 0.0 0.12 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Pro_isomerase PF00160.16 CAR21305.1 - 2.9e-36 125.0 2.5 7.4e-36 123.6 0.8 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD cobW PF02492.14 CAR21306.1 - 5.2e-41 140.0 0.2 7e-41 139.6 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CAR21306.1 - 9.6e-08 31.6 0.1 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.1 CAR21306.1 - 0.001 18.5 0.3 0.0093 15.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CAR21306.1 - 0.0014 18.9 0.1 0.0041 17.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CAR21306.1 - 0.0028 17.3 0.2 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CAR21306.1 - 0.005 15.6 0.6 0.11 11.2 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 CAR21306.1 - 0.0055 16.7 0.0 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CAR21306.1 - 0.0086 16.4 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CAR21306.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 CAR21306.1 - 0.015 15.2 0.0 0.045 13.7 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 CAR21306.1 - 0.028 14.3 0.0 0.082 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CAR21306.1 - 0.033 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 CAR21306.1 - 0.04 13.6 0.6 0.2 11.4 0.1 2.3 2 1 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 CAR21306.1 - 0.052 13.6 0.2 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CAR21306.1 - 0.061 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 CAR21306.1 - 0.08 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CAR21306.1 - 0.087 12.5 0.3 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 CAR21306.1 - 0.13 11.0 0.1 8 5.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.1 CAR21306.1 - 0.25 12.1 1.7 0.65 10.8 1.2 2.2 1 1 0 1 1 1 0 AAA domain Glyco_transf_22 PF03901.12 CAR21307.1 - 7.2e-30 104.3 13.4 9.3e-30 103.9 9.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Img2 PF05046.9 CAR21308.1 - 7.5e-24 83.7 0.1 1.1e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 CAR21308.1 - 0.00094 18.9 0.3 0.0034 17.1 0.2 1.8 1 1 0 1 1 1 1 Translation initiation factor SUI1 WD40 PF00400.27 CAR21309.1 - 9.1e-85 275.8 32.4 1e-14 53.7 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 CAR21309.1 - 1.9e-09 37.5 1.0 0.0001 22.0 0.0 3.7 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 CAR21309.1 - 1.7e-07 31.1 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CAR21309.1 - 2.9e-05 22.3 9.4 0.074 11.1 0.3 4.9 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Gmad1 PF10647.4 CAR21309.1 - 8.4e-05 22.0 0.0 0.04 13.3 0.0 2.2 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 CAR21309.1 - 0.00065 18.5 1.5 0.24 10.0 0.1 3.6 2 2 0 2 2 2 1 Nup133 N terminal like Nbas_N PF15492.1 CAR21309.1 - 0.0024 17.0 0.6 0.58 9.2 0.1 3.1 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CAR21309.1 - 0.0026 16.1 0.0 0.15 10.3 0.0 2.6 2 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 CAR21309.1 - 0.0061 16.1 0.1 2.6 7.7 0.0 3.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 CAR21309.1 - 0.055 12.9 0.0 0.22 11.0 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 CAR21309.1 - 0.52 10.0 5.7 11 5.7 0.0 3.9 3 2 2 5 5 5 0 Transcription factor IIIC subunit delta N-term Pkinase PF00069.20 CAR21310.1 - 2.1e-67 227.0 0.0 7.7e-67 225.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21310.1 - 6.6e-39 133.5 0.0 1.5e-38 132.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR21310.1 - 1.2e-07 31.0 0.0 5e-06 25.6 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAR21310.1 - 0.02 14.6 0.0 0.055 13.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.23 CAR21311.1 - 3.4e-37 127.8 0.2 5e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.18 CAR21312.1 - 6e-07 28.7 0.2 7.4e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAR21312.1 - 0.0001 21.8 0.1 0.00011 21.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR21312.1 - 0.093 12.9 0.3 0.54 10.5 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain FTCD PF02971.9 CAR21312.1 - 0.096 12.3 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Formiminotransferase domain Chorismate_bind PF00425.13 CAR21313.1 - 2e-65 220.6 0.0 3e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 CAR21313.1 - 5.9e-33 113.9 0.0 1.1e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CAR21313.1 - 5.6e-12 45.8 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CAR21313.1 - 6.2e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CP2 PF04516.10 CAR21313.1 - 0.14 11.1 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 CP2 transcription factor Glucosamine_iso PF01182.15 CAR21314.1 - 1.8e-46 158.4 0.0 3.5e-46 157.4 0.0 1.4 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PQ-loop PF04193.9 CAR21315.1 - 2.9e-20 71.5 10.8 7.8e-12 44.5 0.0 2.6 3 0 0 3 3 3 2 PQ loop repeat DUF588 PF04535.7 CAR21315.1 - 0.14 11.6 2.7 3.9 7.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF588) LMBR1 PF04791.11 CAR21316.1 - 2.6e-11 42.7 18.1 5.7e-11 41.6 12.5 1.5 1 1 0 1 1 1 1 LMBR1-like membrane protein Pox_A14 PF05767.7 CAR21316.1 - 0.0034 17.3 2.4 0.0034 17.3 1.6 2.7 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 SHR3_chaperone PF08229.6 CAR21316.1 - 0.0077 15.1 1.7 0.017 14.0 1.2 1.5 1 0 0 1 1 1 1 ER membrane protein SH3 TRIQK PF15168.1 CAR21316.1 - 0.056 13.3 0.2 0.26 11.2 0.1 2.2 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family DUF3215 PF11503.3 CAR21317.1 - 7.3e-27 92.8 0.1 8.3e-27 92.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PI31_Prot_C PF08577.6 CAR21318.1 - 9.7e-10 38.9 17.0 2.5e-09 37.6 11.8 1.7 1 0 0 1 1 1 1 PI31 proteasome regulator PAT1 PF09770.4 CAR21319.1 - 1e-246 821.1 9.8 1.2e-246 820.9 6.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 P34-Arc PF04045.9 CAR21320.1 - 9.3e-97 323.0 1.5 1.1e-96 322.7 1.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Ribosom_S12_S23 PF00164.20 CAR21321.1 - 3.1e-42 142.8 2.1 3.8e-42 142.5 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PP2C PF00481.16 CAR21322.1 - 2.2e-34 119.0 0.0 7.2e-30 104.2 0.0 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CAR21322.1 - 0.00013 21.4 0.0 0.00029 20.2 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Ribosomal_S19 PF00203.16 CAR21323.1 - 3e-22 78.0 0.0 3.9e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.24 CAR21324.1 - 3.1e-39 134.1 0.3 6.2e-39 133.1 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR21324.1 - 3.8e-20 71.5 0.1 1.5e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR21324.1 - 3.4e-07 30.2 0.1 3.4e-07 30.2 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CAR21324.1 - 0.01 15.5 0.5 0.067 12.9 0.1 2.5 1 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 CAR21324.1 - 0.065 13.3 0.6 0.25 11.4 0.2 2.1 2 1 0 2 2 2 0 AAA domain DUF740 PF05340.7 CAR21324.1 - 1.6 6.9 10.3 2.4 6.3 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Med12 PF09497.5 CAR21325.1 - 2e-23 82.1 0.4 1.5e-22 79.3 0.1 2.4 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Cation_efflux PF01545.16 CAR21326.1 - 2e-06 27.1 12.0 2e-06 27.1 8.3 2.2 2 1 0 2 2 2 1 Cation efflux family UbiA PF01040.13 CAR21327.1 - 5.7e-30 104.3 15.5 7.2e-30 104.0 10.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Thioredoxin PF00085.15 CAR21329.1 - 1.3e-25 89.1 0.0 1.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAR21329.1 - 1.6e-05 24.9 0.1 3.9e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CAR21329.1 - 2.1e-05 24.1 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAR21329.1 - 6.9e-05 22.4 0.0 8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 CAR21329.1 - 0.0011 19.1 0.2 0.017 15.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CAR21329.1 - 0.0021 17.6 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CAR21329.1 - 0.0023 17.9 0.1 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 CAR21329.1 - 0.025 14.0 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein GHMP_kinases_N PF00288.21 CAR21331.1 - 3.4e-11 43.0 0.7 2.8e-10 40.1 0.5 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain Zn_clus PF00172.13 CAR21332.1 - 9.7e-08 31.7 8.2 1.7e-07 31.0 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 CAR21333.1 - 4.9e-62 203.7 15.8 3.8e-10 39.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CAR21333.1 - 1.8e-30 104.9 12.2 1.8e-30 104.9 8.4 2.9 2 1 0 2 2 1 1 Tup N-terminal SPX PF03105.14 CAR21333.1 - 0.047 13.4 20.3 0.08 12.7 14.0 1.4 1 0 0 1 1 1 0 SPX domain Ycf1 PF05758.7 CAR21333.1 - 0.083 10.6 16.0 0.11 10.1 11.1 1.2 1 0 0 1 1 1 0 Ycf1 Mem_trans PF03547.13 CAR21333.1 - 0.14 10.4 0.3 0.16 10.2 0.2 1.2 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 CAR21333.1 - 0.22 9.1 21.3 0.3 8.7 14.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CAR21333.1 - 0.27 11.0 13.0 0.46 10.3 9.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 CAR21333.1 - 0.34 9.4 5.6 0.44 9.0 3.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AUX_IAA PF02309.11 CAR21333.1 - 0.42 10.3 15.4 0.73 9.5 10.7 1.4 1 0 0 1 1 1 0 AUX/IAA family DUF4175 PF13779.1 CAR21333.1 - 0.58 7.7 63.4 0.94 7.0 43.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SpoVR PF04293.8 CAR21333.1 - 0.64 8.3 22.9 0.98 7.7 15.9 1.1 1 0 0 1 1 1 0 SpoVR like protein Baculo_PP31 PF05311.6 CAR21333.1 - 1.1 8.4 20.8 1 8.6 13.3 1.7 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF4045 PF13254.1 CAR21333.1 - 1.2 8.3 24.3 1.9 7.7 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 CAR21333.1 - 1.2 7.0 20.3 1.9 6.4 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CDK5_activator PF03261.10 CAR21333.1 - 2.1 7.6 25.0 3.5 6.8 17.3 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AIF_C PF14721.1 CAR21333.1 - 2.2 8.5 17.6 8 6.7 12.2 2.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rtf2 PF04641.7 CAR21333.1 - 2.3 7.3 22.7 3.8 6.6 15.8 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger FLO_LFY PF01698.11 CAR21333.1 - 3.1 6.5 23.2 4.7 5.9 16.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Plasmodium_Vir PF05795.6 CAR21333.1 - 4.1 6.5 7.1 7.4 5.6 4.9 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.1 CAR21333.1 - 4.2 7.0 17.6 7.5 6.2 12.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.7 CAR21333.1 - 4.4 5.7 29.8 6.7 5.2 20.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.17 CAR21333.1 - 4.5 6.1 11.2 6.7 5.6 7.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter vMSA PF00695.14 CAR21333.1 - 4.7 6.3 11.8 9.8 5.2 8.1 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Dicty_REP PF05086.7 CAR21333.1 - 9.9 3.7 15.5 14 3.2 10.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Csm1 PF12539.3 CAR21334.1 - 1.3e-33 115.2 0.0 2.7e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 AAA_27 PF13514.1 CAR21334.1 - 0.0012 16.6 1.8 0.0015 16.3 1.2 1.1 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 CAR21334.1 - 0.0056 16.1 2.5 0.0097 15.4 1.2 1.7 2 0 0 2 2 2 1 Intermediate filament protein TMCO5 PF14992.1 CAR21334.1 - 0.0099 15.0 1.3 0.014 14.5 0.9 1.2 1 0 0 1 1 1 1 TMCO5 family HOOK PF05622.7 CAR21334.1 - 0.016 13.0 1.0 0.022 12.6 0.7 1.1 1 0 0 1 1 1 0 HOOK protein DUF641 PF04859.7 CAR21334.1 - 0.021 14.6 1.5 0.021 14.6 1.0 1.7 2 0 0 2 2 1 0 Plant protein of unknown function (DUF641) GAS PF13851.1 CAR21334.1 - 0.047 12.8 2.8 0.035 13.3 0.6 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Complex1_49kDa PF00346.14 CAR21334.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.4 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF3498 PF12004.3 CAR21334.1 - 0.065 12.3 1.6 0.088 11.9 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) CALCOCO1 PF07888.6 CAR21334.1 - 0.07 11.4 2.8 0.097 10.9 1.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-Q PF13094.1 CAR21334.1 - 0.074 13.0 3.9 0.079 12.9 1.5 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.6 CAR21334.1 - 0.42 10.3 3.7 0.22 11.2 0.8 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Mnd1 PF03962.10 CAR21334.1 - 0.45 10.1 4.4 0.12 12.0 0.8 1.7 2 0 0 2 2 2 0 Mnd1 family PspA_IM30 PF04012.7 CAR21334.1 - 0.74 9.1 9.4 0.04 13.2 3.0 1.4 2 0 0 2 2 2 0 PspA/IM30 family Mod_r PF07200.8 CAR21334.1 - 0.85 9.5 5.6 0.78 9.6 1.0 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.7 CAR21334.1 - 5.4 7.4 6.1 0.75 10.2 1.0 2.0 2 0 0 2 2 2 0 SlyX Med9 PF07544.8 CAR21334.1 - 5.6 6.7 6.7 0.47 10.2 1.2 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-LYAR PF08790.6 CAR21335.1 - 1.8e-14 53.1 5.5 4e-14 51.9 3.8 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Draxin PF15550.1 CAR21335.1 - 0.025 14.2 9.6 0.027 14.1 6.7 1.1 1 0 0 1 1 1 0 Draxin C1_4 PF07975.7 CAR21335.1 - 0.055 13.4 4.9 0.22 11.5 3.4 2.1 1 0 0 1 1 1 0 TFIIH C1-like domain zf-TRAF PF02176.13 CAR21335.1 - 0.092 13.1 2.3 0.17 12.2 1.6 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger DHHW PF14286.1 CAR21335.1 - 0.12 11.6 6.5 0.15 11.3 4.5 1.1 1 0 0 1 1 1 0 DHHW protein zf-met PF12874.2 CAR21335.1 - 0.16 12.2 3.5 3.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Peptidase_C58 PF03543.9 CAR21335.1 - 0.31 10.4 9.2 0.4 10.1 6.4 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Neur_chan_memb PF02932.11 CAR21335.1 - 0.49 10.2 7.2 0.52 10.1 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-GRF PF06839.7 CAR21335.1 - 0.7 9.8 5.4 2.2 8.2 3.7 1.9 1 0 0 1 1 1 0 GRF zinc finger TraV PF09676.5 CAR21335.1 - 0.89 10.2 9.0 1.7 9.3 6.2 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Trypan_PARP PF05887.6 CAR21335.1 - 1.2 8.9 6.0 1.7 8.4 4.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C2H2_jaz PF12171.3 CAR21335.1 - 1.4 9.1 4.7 2.4 8.3 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RNHCP PF12647.2 CAR21335.1 - 1.4 8.7 4.6 4.8 7.0 3.2 1.9 1 1 0 1 1 1 0 RNHCP domain A2L_zn_ribbon PF08792.5 CAR21335.1 - 2.7 7.5 8.5 52 3.4 5.9 2.6 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF2201_N PF13203.1 CAR21335.1 - 4.9 6.2 8.9 5.4 6.1 6.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Cofilin_ADF PF00241.15 CAR21336.1 - 4.2e-20 71.9 0.0 8.4e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.1 CAR21336.1 - 2.8e-14 52.4 0.1 6.8e-14 51.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR21336.1 - 2.9e-14 52.1 0.6 7.8e-14 50.7 0.4 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CAR21336.1 - 2.5e-07 30.0 0.0 4.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Flocculin_t3 PF13928.1 CAR21337.1 - 1.5e-14 53.8 73.6 8.3e-06 25.8 5.5 14.6 13 1 0 13 13 13 6 Flocculin type 3 repeat DUF866 PF05907.8 CAR21338.1 - 2.6e-29 101.7 6.2 3.1e-19 69.0 1.3 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) GSH-S_N PF02951.9 CAR21338.1 - 0.059 13.1 0.0 0.53 10.1 0.0 2.0 1 1 1 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain zf-BED PF02892.10 CAR21338.1 - 2.3 8.0 8.8 0.42 10.3 1.0 2.4 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.8 CAR21338.1 - 2.5 7.8 7.5 23 4.7 0.2 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like TetR_C_8 PF14278.1 CAR21339.1 - 0.032 14.6 1.2 0.18 12.2 0.3 2.5 1 1 1 2 2 2 0 Transcriptional regulator C-terminal region Trm112p PF03966.11 CAR21340.1 - 4.3e-20 71.8 0.1 5.3e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Pkinase PF00069.20 CAR21341.1 - 4.9e-74 248.7 0.2 6.8e-74 248.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21341.1 - 6.4e-32 110.6 0.2 1.3e-30 106.3 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR21341.1 - 2.3e-09 36.6 0.4 2.1e-06 26.9 0.0 2.5 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 CAR21341.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MutS_V PF00488.16 CAR21342.1 - 1.1e-77 260.6 0.0 1.8e-77 259.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR21342.1 - 1.6e-37 129.3 2.1 1.6e-37 129.3 1.5 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 CAR21342.1 - 1.7e-28 98.9 0.1 3.2e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CAR21342.1 - 4e-09 36.5 2.0 1.3e-08 34.8 0.4 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 CAR21342.1 - 0.0006 19.8 1.0 0.013 15.5 0.0 3.4 3 1 1 4 4 4 1 MutS domain II Not1 PF04054.10 CAR21343.1 - 3.5e-140 467.1 5.5 3.5e-140 467.1 3.8 3.3 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CAR21343.1 - 2.4e-42 144.0 6.9 2.4e-42 144.0 4.8 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3819) Med15 PF09606.5 CAR21343.1 - 1.7 6.7 111.4 0.0097 14.1 56.9 2.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC50 PF03381.10 CAR21344.1 - 9.4e-102 339.8 0.4 1.1e-101 339.6 0.3 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family UQ_con PF00179.21 CAR21345.1 - 1.9e-42 144.0 0.0 2.4e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CAR21345.1 - 4.6e-27 93.3 0.3 9.9e-27 92.3 0.2 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_2 PF08587.6 CAR21345.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Mso1_Sec1_bdg PF14475.1 CAR21346.1 - 1e-19 69.6 0.1 1.7e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Saccharop_dh PF03435.13 CAR21347.1 - 6.1e-126 420.4 0.0 8.2e-126 420.0 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CAR21347.1 - 1.8e-06 28.0 0.2 3.1e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CAR21347.1 - 0.00028 20.9 0.5 0.0005 20.1 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 CAR21347.1 - 0.0057 17.0 0.3 0.011 16.0 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 CAR21347.1 - 0.0071 15.0 0.1 0.0099 14.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CAR21347.1 - 0.039 14.2 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF2325 PF10087.4 CAR21347.1 - 0.048 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_3 PF03447.11 CAR21347.1 - 0.079 13.3 0.4 0.14 12.5 0.3 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Y_phosphatase2 PF03162.8 CAR21348.1 - 1.1e-32 112.6 1.5 5.4e-31 107.1 1.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family NTF2 PF02136.15 CAR21349.1 - 2.1e-18 66.7 0.2 4.5e-18 65.7 0.2 1.6 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain CAF1 PF04857.15 CAR21350.1 - 1.5e-52 178.5 3.2 2.3e-52 177.9 2.2 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NGP1NT PF08153.7 CAR21351.1 - 2.5e-49 166.5 0.2 4.6e-49 165.6 0.2 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CAR21351.1 - 1.1e-19 70.5 0.0 4.4e-15 55.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR21351.1 - 1.7e-05 24.1 0.0 9.4e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR21351.1 - 2.8e-05 24.0 0.8 0.3 10.8 0.0 3.7 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 CAR21351.1 - 0.00065 19.1 0.6 0.22 10.9 0.1 3.6 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CAR21351.1 - 0.00068 18.8 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 CAR21351.1 - 0.00088 18.5 0.1 0.25 10.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family SusD-like_3 PF14322.1 CAR21351.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Starch-binding associating with outer membrane RRM_5 PF13893.1 CAR21352.1 - 0.00011 21.9 0.1 0.0012 18.6 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR21352.1 - 0.00027 20.5 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21352.1 - 0.001 18.9 0.0 0.0089 15.9 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) B3 PF02362.16 CAR21352.1 - 0.06 12.9 0.6 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 B3 DNA binding domain Zip PF02535.17 CAR21353.1 - 2e-51 174.8 5.0 2e-51 174.8 3.5 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter UNC-50 PF05216.8 CAR21353.1 - 2.6 7.1 7.8 0.96 8.5 2.5 2.2 2 0 0 2 2 2 0 UNC-50 family DLH PF01738.13 CAR21354.1 - 1.9e-28 99.2 0.1 2.2e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CAR21354.1 - 6.7e-08 32.4 0.0 8.7e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR21354.1 - 0.0021 18.0 0.0 0.0032 17.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 CAR21355.1 - 1.2e-49 168.9 3.5 1.5e-49 168.6 2.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR21355.1 - 1.5e-09 37.5 11.0 3.4e-09 36.4 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 CAR21356.1 - 6.6e-33 114.7 0.2 1.1e-32 114.0 0.2 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CAR21356.1 - 1.4e-15 58.1 0.0 7.9e-08 32.6 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CAR21356.1 - 2.3e-14 52.9 0.0 1.1e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CAR21356.1 - 2.4e-13 50.1 3.0 4.6e-11 42.5 0.1 2.1 1 1 1 2 2 2 2 Amidohydrolase family MFS_1 PF07690.11 CAR21357.1 - 1.9e-37 128.8 27.2 1.9e-37 128.8 18.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2721 PF11026.3 CAR21357.1 - 4 7.0 9.2 3.5 7.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) MFS_1 PF07690.11 CAR21358.1 - 3e-12 45.9 43.1 8.9e-12 44.3 27.4 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR21358.1 - 3.2e-06 26.0 13.5 3.2e-06 26.0 9.4 3.1 3 2 0 3 3 3 1 Sugar (and other) transporter DUF4566 PF15130.1 CAR21358.1 - 0.059 12.5 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) D-ser_dehydrat PF14031.1 CAR21359.1 - 2.6e-21 75.5 0.0 5.7e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CAR21359.1 - 5.9e-12 45.6 0.0 8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain adh_short_C2 PF13561.1 CAR21361.1 - 1.9e-23 83.4 0.1 2.3e-23 83.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR21361.1 - 9.3e-18 64.6 0.0 1.2e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR21361.1 - 1.5e-11 44.2 0.0 2.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CAR21361.1 - 0.079 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pab87_oct PF13969.1 CAR21361.1 - 0.084 12.9 0.1 0.29 11.2 0.0 2.0 1 1 0 1 1 1 0 Pab87 octamerisation domain Aldo_ket_red PF00248.16 CAR21362.1 - 5e-62 209.2 0.0 5.6e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 CAR21365.1 - 5.4e-13 48.3 39.8 2.7e-12 46.1 26.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 CAR21365.1 - 0.35 10.1 7.3 0.93 8.7 1.3 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF21 MFS_1 PF07690.11 CAR21366.1 - 6.6e-37 127.0 53.0 5e-30 104.4 18.9 3.0 2 1 2 4 4 4 2 Major Facilitator Superfamily TRI12 PF06609.8 CAR21366.1 - 1.1e-14 53.5 16.3 1.3e-14 53.3 10.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease PF00324.16 CAR21367.1 - 1.4e-104 350.1 45.0 1.7e-104 349.8 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR21367.1 - 2.2e-22 79.2 46.9 3e-22 78.7 32.5 1.2 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.16 CAR21368.1 - 9.4e-16 57.7 0.0 1.2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CAR21368.1 - 2.9e-05 22.8 0.0 6.6e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.16 CAR21369.1 - 8.5e-106 353.6 0.0 1.1e-105 353.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CAR21369.1 - 0.00034 19.8 0.0 0.00068 18.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CAR21369.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Amidohydro_1 PF01979.15 CAR21370.1 - 7.8e-30 104.6 0.2 1e-29 104.2 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CAR21370.1 - 2.9e-15 57.0 0.0 1.1e-13 51.8 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 CAR21370.1 - 1.3e-11 44.0 0.0 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CAR21370.1 - 1.1e-08 34.6 0.0 0.0001 21.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family GATase PF00117.23 CAR21371.1 - 4.5e-12 45.8 0.0 5.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CAR21371.1 - 0.0043 16.6 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 CAR21371.1 - 0.035 13.5 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 Alpha-amylase PF00128.19 CAR21372.1 - 4.5e-106 354.8 0.2 6.8e-106 354.2 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 CAR21372.1 - 0.0065 15.4 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 CAR21373.1 - 5.3e-168 559.2 35.3 6e-168 559.0 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR21373.1 - 2.1e-24 85.8 38.3 2.7e-23 82.2 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 CAR21374.1 - 5.9e-11 42.1 10.2 1.4e-10 40.8 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 CAR21376.1 - 9.4e-55 184.6 0.1 3.6e-32 111.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CAR21376.1 - 8.5e-37 127.0 36.4 6.7e-21 74.9 8.8 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CAR21376.1 - 4.9e-12 46.3 0.5 0.0016 18.4 0.1 4.2 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 CAR21376.1 - 2.3e-10 40.1 4.0 0.0088 15.3 0.0 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR21376.1 - 7e-09 36.3 0.7 8.7e-05 22.9 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAR21376.1 - 8e-08 31.7 0.3 0.017 14.6 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CAR21376.1 - 2.1e-07 31.0 1.7 0.0021 18.0 0.0 3.0 4 0 0 4 4 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CAR21376.1 - 2.6e-07 30.3 0.0 0.0069 15.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 CAR21376.1 - 3.4e-07 29.9 2.0 0.025 14.0 0.1 3.3 2 1 1 3 3 3 2 AAA-like domain DUF258 PF03193.11 CAR21376.1 - 1.1e-05 24.6 0.0 0.008 15.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CAR21376.1 - 1.2e-05 25.4 0.3 0.31 11.1 0.2 3.4 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CAR21376.1 - 4e-05 23.1 0.0 0.35 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CAR21376.1 - 7.8e-05 23.4 0.0 0.5 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CAR21376.1 - 0.00026 20.9 0.4 0.31 11.0 0.2 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CAR21376.1 - 0.00049 19.2 0.1 0.084 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.12 CAR21376.1 - 0.0012 18.7 1.3 0.0096 15.7 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SE PF00437.15 CAR21376.1 - 0.0026 16.7 0.1 1.7 7.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 CAR21376.1 - 0.0028 17.3 0.6 0.5 10.0 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CAR21376.1 - 0.0035 16.9 0.0 0.9 9.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR21376.1 - 0.004 17.0 0.0 2.6 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CAR21376.1 - 0.0058 17.1 0.1 7.7 7.0 0.1 3.0 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CAR21376.1 - 0.0086 15.9 1.2 1.2 8.9 0.1 2.7 2 0 0 2 2 2 1 Dynamin family Pox_A32 PF04665.7 CAR21376.1 - 0.011 15.1 0.9 1.2 8.4 0.1 2.7 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.1 CAR21376.1 - 0.011 15.9 0.4 6 7.1 0.2 2.7 2 0 0 2 2 2 0 AAA domain SopA PF13981.1 CAR21376.1 - 0.025 14.5 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 SopA-like central domain Arch_ATPase PF01637.13 CAR21376.1 - 0.032 13.9 0.9 4 7.0 0.0 3.4 3 0 0 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 CAR21376.1 - 0.035 13.8 0.0 2.9 7.6 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 CAR21376.1 - 0.063 12.9 0.5 5.5 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CAR21376.1 - 0.066 13.3 0.0 5.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 CAR21376.1 - 0.094 12.2 0.3 3.4 7.1 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DEAD PF00270.24 CAR21376.1 - 0.12 11.8 0.2 9.9 5.6 0.0 2.8 3 0 0 3 3 2 0 DEAD/DEAH box helicase ResIII PF04851.10 CAR21376.1 - 0.12 12.1 0.8 2.1 8.1 0.0 2.9 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit SbcCD_C PF13558.1 CAR21376.1 - 0.13 12.2 0.1 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CAR21376.1 - 0.13 11.3 0.0 7 5.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 CAR21376.1 - 0.15 11.5 0.1 13 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CAR21376.1 - 0.18 10.7 0.1 14 4.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dak1 PF02733.12 CAR21377.1 - 4.8e-144 478.9 0.6 6e-144 478.5 0.4 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CAR21377.1 - 3.3e-44 150.6 2.0 7.5e-44 149.4 1.4 1.6 1 0 0 1 1 1 1 DAK2 domain MIP PF00230.15 CAR21378.1 - 2.4e-49 167.8 9.5 3.9e-49 167.1 6.6 1.3 1 0 0 1 1 1 1 Major intrinsic protein FMO-like PF00743.14 CAR21379.1 - 1.9e-30 105.5 0.2 5.1e-16 57.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CAR21379.1 - 7.5e-09 35.9 0.0 8.2e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR21379.1 - 2.2e-05 24.4 0.0 0.039 13.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CAR21379.1 - 0.00017 20.5 0.0 0.01 14.7 0.0 2.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CAR21379.1 - 0.0051 16.6 0.0 0.43 10.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.10 CAR21379.1 - 0.048 11.8 0.0 0.098 10.8 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) DAO PF01266.19 CAR21379.1 - 0.16 10.8 0.0 2.7 6.7 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Sugar_tr PF00083.19 CAR21380.1 - 6.4e-73 245.8 27.2 8.7e-73 245.4 18.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR21380.1 - 1.5e-25 89.6 28.3 1.5e-25 89.6 19.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Pam17 PF08566.5 CAR21380.1 - 0.13 11.8 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 ADH_zinc_N PF00107.21 CAR21381.1 - 1.1e-12 47.5 0.0 1.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR21381.1 - 7.1e-07 28.9 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CAR21381.1 - 0.0051 17.7 0.0 0.0098 16.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Bac_luciferase PF00296.15 CAR21382.1 - 5.1e-49 167.0 0.0 8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 CAR21383.1 - 1.7e-14 53.3 25.3 1.7e-14 53.3 17.5 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family MFS_1 PF07690.11 CAR21385.1 - 1.8e-17 63.1 24.4 1.8e-17 63.1 16.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 CAR21386.1 - 3.5e-38 131.2 56.8 7.1e-32 110.4 24.4 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR21386.1 - 6.7e-09 34.8 21.4 6.7e-09 34.8 14.8 3.1 4 0 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 CAR21386.1 - 3.9e-08 31.9 28.0 2.5e-07 29.2 19.4 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NifU_N PF01592.11 CAR21388.1 - 0.063 13.2 0.4 0.09 12.7 0.3 1.3 1 0 0 1 1 1 0 NifU-like N terminal domain Adhesin_Dr PF04619.7 CAR21389.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Dr-family adhesin Aa_trans PF01490.13 CAR21390.1 - 3.2e-26 91.7 38.0 4e-26 91.4 26.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3938 PF13074.1 CAR21390.1 - 0.045 13.6 0.5 0.045 13.6 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3938) Mito_carr PF00153.22 CAR21391.1 - 8.4e-49 163.2 7.9 3.1e-20 71.6 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.7 CAR21391.1 - 0.26 11.0 3.2 1.1 9.0 0.0 3.0 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family FoP_duplication PF13865.1 CAR21392.1 - 6.2e-09 36.1 1.7 8.6e-09 35.7 1.2 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Limkain-b1 PF11608.3 CAR21392.1 - 0.066 12.9 0.4 0.1 12.3 0.3 1.2 1 0 0 1 1 1 0 Limkain b1 CRCB PF02537.10 CAR21393.1 - 5.2e-33 113.4 17.3 4.4e-22 78.1 4.5 2.5 2 1 0 2 2 2 2 CrcB-like protein PUL PF08324.6 CAR21394.1 - 5.7e-54 182.7 0.1 7.5e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 CAR21394.1 - 8.3e-45 149.1 13.0 4.7e-08 32.6 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat PFU PF09070.6 CAR21394.1 - 3.6e-38 130.1 0.0 7.4e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Proteasom_PSMB PF10508.4 CAR21394.1 - 0.023 12.9 0.0 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Syja_N PF02383.13 CAR21395.1 - 2.3e-83 279.5 0.2 3.1e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain IGPS PF00218.16 CAR21396.1 - 2.1e-89 298.9 0.1 3.1e-89 298.3 0.1 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 CAR21396.1 - 4.4e-51 173.0 0.0 7.4e-51 172.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CAR21396.1 - 3.5e-10 39.6 0.1 7.1e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 CAR21396.1 - 0.00065 19.2 0.1 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain VTC PF09359.5 CAR21396.1 - 0.035 13.1 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 VTC domain Peripla_BP_2 PF01497.13 CAR21396.1 - 0.071 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein Antimicrobial10 PF08105.6 CAR21396.1 - 0.089 12.4 0.0 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 Metchnikowin family Septin PF00735.13 CAR21397.1 - 6e-107 356.8 0.0 6e-107 356.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CAR21397.1 - 2.6e-07 30.5 0.0 6.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAR21397.1 - 1e-06 28.6 6.9 0.00075 19.3 0.2 3.1 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 CAR21397.1 - 7.3e-05 21.9 0.1 7.3e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CAR21397.1 - 0.00025 20.2 0.6 0.0015 17.7 0.4 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CAR21397.1 - 0.0025 18.1 0.6 0.0081 16.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 CAR21397.1 - 0.0065 15.9 0.1 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain IIGP PF05049.8 CAR21397.1 - 0.0071 15.2 0.1 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 CAR21397.1 - 0.011 16.2 1.5 0.016 15.6 0.1 2.1 2 1 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 CAR21397.1 - 0.074 12.5 0.3 6.9 6.1 0.0 2.6 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 CAR21397.1 - 0.078 12.3 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CAR21397.1 - 0.098 12.2 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CAR21397.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.13 CAR21397.1 - 0.12 11.6 0.4 2.4 7.4 0.3 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B OmpH PF03938.9 CAR21397.1 - 2.7 7.9 9.1 4.4 7.2 6.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Gly_transf_sug PF04488.10 CAR21398.1 - 4.2e-11 43.1 0.2 1.2e-10 41.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif CAGE1 PF15066.1 CAR21398.1 - 0.046 12.1 1.7 0.066 11.6 1.2 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family DivIC PF04977.10 CAR21398.1 - 0.61 9.6 3.8 1.2 8.6 2.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Mog1 PF04603.7 CAR21399.1 - 4.6e-19 68.7 0.3 2.6e-17 63.0 0.2 2.6 1 1 0 1 1 1 1 Ran-interacting Mog1 protein ThiF PF00899.16 CAR21400.1 - 2e-53 179.8 0.0 6.9e-32 110.1 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CAR21400.1 - 2.5e-44 150.4 0.1 1.1e-43 148.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CAR21400.1 - 2e-32 110.5 0.1 3.1e-22 77.9 0.0 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAR21400.1 - 8.7e-27 92.2 0.2 6.3e-21 73.4 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site ABC_membrane PF00664.18 CAR21401.1 - 2.9e-79 266.3 24.0 2.2e-40 138.7 4.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAR21401.1 - 2.9e-61 205.7 0.1 2.1e-31 109.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CAR21401.1 - 2.7e-14 52.9 7.5 9.1e-07 28.3 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR21401.1 - 2.3e-08 33.4 2.6 0.003 17.0 0.6 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CAR21401.1 - 1.2e-05 24.5 0.2 0.096 11.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAR21401.1 - 1.9e-05 25.4 0.1 0.31 11.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CAR21401.1 - 6.2e-05 23.3 0.0 0.42 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAR21401.1 - 0.00021 21.3 2.1 0.34 10.8 0.5 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CAR21401.1 - 0.00026 20.7 0.8 1.3 8.6 0.1 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CAR21401.1 - 0.00032 20.6 0.0 0.27 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CAR21401.1 - 0.00059 19.9 4.4 1.6 8.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.1 CAR21401.1 - 0.0013 18.8 8.2 0.15 12.0 0.2 4.1 3 1 1 4 4 4 1 AAA domain AAA_25 PF13481.1 CAR21401.1 - 0.0014 18.0 2.2 0.27 10.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CAR21401.1 - 0.0014 18.5 0.2 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 CAR21401.1 - 0.0047 17.2 1.1 0.53 10.5 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CAR21401.1 - 0.0086 15.5 11.5 1.3 8.3 1.3 4.4 4 2 0 5 5 5 2 AAA-like domain ABC_ATPase PF09818.4 CAR21401.1 - 0.017 13.7 0.1 3 6.3 0.0 2.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 CAR21401.1 - 0.024 14.0 0.3 0.73 9.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family APS_kinase PF01583.15 CAR21401.1 - 0.026 14.1 0.7 5.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.7 CAR21401.1 - 0.082 12.5 3.0 7.5 6.1 0.0 3.4 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.7 CAR21401.1 - 0.11 11.6 0.1 8.2 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 CAR21401.1 - 0.13 11.9 1.2 4.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PEMT PF04191.8 CAR21402.1 - 9.2e-34 115.7 2.4 2.3e-33 114.4 1.6 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF4118 PF13493.1 CAR21402.1 - 0.041 14.0 0.1 0.041 14.0 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) MMR_HSR1_C PF08438.5 CAR21403.1 - 3.5e-31 107.6 0.0 5.9e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CAR21403.1 - 3e-18 65.8 0.0 5.9e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR21403.1 - 7.1e-07 28.6 0.1 6.7e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CAR21403.1 - 0.0011 18.4 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAR21403.1 - 0.01 15.7 0.3 0.044 13.5 0.1 2.1 3 0 0 3 3 3 1 Dynamin family AAA_17 PF13207.1 CAR21403.1 - 0.033 15.0 0.3 0.71 10.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 CAR21403.1 - 0.068 12.6 0.3 7.9 5.9 0.0 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CAR21403.1 - 0.088 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 CAR21403.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 CAR21403.1 - 0.1 11.9 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 CAR21403.1 - 0.16 12.2 0.0 0.52 10.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 CAR21403.1 - 0.17 10.5 0.0 0.17 10.5 0.0 2.6 3 1 1 4 4 4 0 ArgK protein AA_permease PF00324.16 CAR21404.1 - 7.1e-120 400.5 42.2 8.5e-120 400.2 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR21404.1 - 2.9e-34 118.3 43.3 3.8e-34 117.9 29.9 1.2 1 1 0 1 1 1 1 Amino acid permease TPP_enzyme_M PF00205.17 CAR21405.1 - 1.4e-36 125.2 0.0 4.5e-35 120.3 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CAR21405.1 - 1.1e-33 116.1 0.0 1.7e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAR21405.1 - 5.9e-13 48.6 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 CAR21405.1 - 0.012 15.1 0.0 0.045 13.3 0.0 1.9 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit OCC1 PF15506.1 CAR21405.1 - 0.075 12.9 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 OCC1 family RRM_6 PF14259.1 CAR21406.1 - 0.083 12.8 0.2 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CLASP_N PF12348.3 CAR21407.1 - 6.4e-11 42.0 6.5 8.7e-10 38.3 0.2 2.9 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 CAR21407.1 - 4.4e-05 23.2 9.9 0.23 11.6 0.0 7.2 8 0 0 8 8 7 1 HEAT repeat Tropomyosin_1 PF12718.2 CAR21407.1 - 0.00036 20.4 4.1 0.0012 18.6 2.8 1.9 1 0 0 1 1 1 1 Tropomyosin like HEAT_2 PF13646.1 CAR21407.1 - 0.00078 19.6 0.5 3.2 8.0 0.1 4.4 2 2 2 4 4 4 1 HEAT repeats RIX1 PF08167.7 CAR21407.1 - 0.0027 17.3 2.1 5.8 6.5 0.0 3.8 2 1 1 3 3 3 1 rRNA processing/ribosome biogenesis MscS_porin PF12795.2 CAR21407.1 - 0.0034 16.7 9.9 0.011 15.0 6.9 1.9 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Med9 PF07544.8 CAR21407.1 - 0.0065 16.1 3.7 6.8 6.5 2.4 3.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.16 CAR21407.1 - 0.0083 16.0 1.2 0.23 11.4 0.0 3.1 1 1 1 2 2 2 1 bZIP transcription factor TPR_MLP1_2 PF07926.7 CAR21407.1 - 0.011 15.4 2.5 0.011 15.4 1.8 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.6 CAR21407.1 - 0.012 15.0 2.9 0.03 13.6 2.0 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Myosin_tail_1 PF01576.14 CAR21407.1 - 0.012 13.4 8.3 0.0079 13.9 4.0 1.9 2 0 0 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 CAR21407.1 - 0.036 13.2 0.7 0.08 12.1 0.5 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF812 PF05667.6 CAR21407.1 - 0.075 11.5 10.1 0.016 13.7 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.4 CAR21407.1 - 0.1 12.4 11.5 17 5.2 7.9 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CAR21407.1 - 0.16 11.5 13.8 0.014 15.0 5.7 2.0 2 0 0 2 2 2 0 IncA protein CCDC144C PF14915.1 CAR21407.1 - 0.18 10.6 10.3 0.076 11.9 3.6 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF3450 PF11932.3 CAR21407.1 - 0.22 10.7 6.7 0.49 9.6 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Condensin2nSMC PF12422.3 CAR21407.1 - 0.28 10.9 2.4 2.9 7.6 0.3 2.9 2 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit ATG16 PF08614.6 CAR21407.1 - 0.48 10.2 11.4 0.43 10.3 6.3 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin PF00261.15 CAR21407.1 - 0.63 9.0 8.4 0.15 11.0 1.3 2.6 2 0 0 2 2 2 0 Tropomyosin Spc7 PF08317.6 CAR21407.1 - 0.97 8.0 10.3 0.33 9.5 3.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Striatin PF08232.7 CAR21407.1 - 1.3 9.3 10.4 1 9.6 5.0 2.6 2 1 0 2 2 1 0 Striatin family DUF972 PF06156.8 CAR21407.1 - 2.8 8.3 8.7 2.1 8.7 3.8 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 CAR21407.1 - 6.7 6.6 7.9 2.9 7.7 0.1 3.1 3 0 0 3 3 2 0 Basic region leucine zipper Thioredoxin PF00085.15 CAR21408.1 - 1.5e-31 108.1 0.6 1.6e-31 108.0 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAR21408.1 - 2.9e-08 33.8 0.4 7.6e-07 29.3 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAR21408.1 - 6e-07 29.4 0.1 4.3e-06 26.7 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CAR21408.1 - 5.7e-06 25.9 0.1 6.9e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 CAR21408.1 - 5e-05 22.8 0.3 0.00055 19.4 0.1 2.0 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.11 CAR21408.1 - 0.00021 20.8 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.16 CAR21408.1 - 0.00031 20.4 0.1 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF2847 PF11009.3 CAR21408.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_7 PF13899.1 CAR21408.1 - 0.016 15.2 0.2 0.027 14.4 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.11 CAR21408.1 - 0.043 12.5 0.0 0.044 12.5 0.0 1.0 1 0 0 1 1 1 0 Phosducin TraF PF13728.1 CAR21408.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 CAR21408.1 - 0.12 12.2 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain HAD PF12710.2 CAR21409.1 - 1.1e-12 48.5 0.0 1.6e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR21409.1 - 4.3e-10 40.3 0.2 6.7e-10 39.7 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAR21409.1 - 1.4e-07 31.4 0.1 3e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR21409.1 - 1.4e-05 25.3 0.1 0.0002 21.6 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CAR21409.1 - 2.8e-05 23.4 0.0 4.9e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Putative Phosphatase DUF2608 PF11019.3 CAR21409.1 - 0.011 14.7 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF705 PF05152.7 CAR21409.1 - 0.06 12.3 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_PPase PF12689.2 CAR21409.1 - 0.071 12.7 0.0 0.39 10.3 0.0 2.0 1 1 0 1 1 1 0 Acid Phosphatase ETF PF01012.16 CAR21410.1 - 2e-35 121.9 0.7 2.7e-35 121.5 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Mvb12 PF09452.5 CAR21411.1 - 3.4e-26 91.2 0.1 3.9e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 3-HAO PF06052.7 CAR21412.1 - 5.9e-63 210.7 0.2 7e-63 210.5 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CAR21412.1 - 2.5e-05 23.6 0.1 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CAR21412.1 - 0.0052 16.2 0.1 0.0074 15.7 0.1 1.2 1 0 0 1 1 1 1 Cupin zf-B_box PF00643.19 CAR21412.1 - 0.043 13.7 3.5 0.1 12.5 0.4 2.3 2 0 0 2 2 2 0 B-box zinc finger FYVE PF01363.16 CAR21412.1 - 0.049 13.5 1.2 0.084 12.7 0.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger AraC_binding PF02311.14 CAR21412.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain zinc_ribbon_2 PF13240.1 CAR21412.1 - 0.2 11.1 4.3 2.7 7.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-RanBP PF00641.13 CAR21412.1 - 0.67 9.1 4.2 0.66 9.1 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others A2L_zn_ribbon PF08792.5 CAR21412.1 - 1.4 8.5 4.9 0.63 9.5 0.2 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Aldolase_II PF00596.16 CAR21413.1 - 1.5e-42 145.2 0.0 1.9e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LSM PF01423.17 CAR21414.1 - 7.2e-13 47.8 0.1 1.1e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 LSM domain Zeta_toxin PF06414.7 CAR21415.1 - 0.00011 21.3 0.0 0.00021 20.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CAR21415.1 - 0.0002 22.1 0.0 0.00041 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CAR21415.1 - 0.0005 19.6 0.0 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 CAR21415.1 - 0.00071 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.17 CAR21415.1 - 0.00098 18.6 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 CAR21415.1 - 0.0019 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 CAR21415.1 - 0.006 16.9 0.0 0.0084 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR21415.1 - 0.0072 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CAR21415.1 - 0.0091 16.3 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR21415.1 - 0.01 15.6 0.2 0.024 14.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CAR21415.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CAR21415.1 - 0.015 14.5 0.1 0.045 12.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.24 CAR21415.1 - 0.03 14.5 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CAR21415.1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CAR21415.1 - 0.038 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 CAR21415.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.10 CAR21415.1 - 0.051 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 CAR21415.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CAR21415.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CAR21415.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 CAR21415.1 - 0.096 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein Acyl_CoA_thio PF02551.10 CAR21416.1 - 7.1e-31 106.5 0.4 3e-25 88.3 0.0 3.1 2 1 1 3 3 3 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 CAR21416.1 - 7.7e-31 107.7 0.3 1e-30 107.3 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily p12I PF12233.3 CAR21416.1 - 0.02 15.1 0.6 0.042 14.1 0.4 1.4 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein FTHFS PF01268.14 CAR21417.1 - 2e-258 857.9 0.3 2.6e-258 857.6 0.2 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CAR21417.1 - 2e-60 202.4 0.9 3.6e-60 201.7 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CAR21417.1 - 6e-39 132.6 0.1 1.3e-38 131.6 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Harakiri PF15196.1 CAR21418.1 - 0.16 12.2 4.9 0.27 11.5 3.4 1.3 1 0 0 1 1 1 0 Activator of apoptosis harakiri Rotamase PF00639.16 CAR21419.1 - 1.7e-24 86.3 0.0 2.4e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CAR21419.1 - 3.1e-16 59.6 0.0 3.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CAR21419.1 - 2.5e-08 33.6 1.0 3.9e-08 33.0 0.7 1.3 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 CAR21419.1 - 1.8e-07 31.8 0.0 2.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rhodanese PF00581.15 CAR21420.1 - 5.9e-10 39.4 0.0 7.4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_2 PF01467.21 CAR21421.1 - 1e-22 80.8 0.0 2.1e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase SDA1 PF05285.7 CAR21421.1 - 0.016 14.4 20.8 0.027 13.7 9.3 2.1 2 0 0 2 2 2 0 SDA1 ILVD_EDD PF00920.16 CAR21422.1 - 4.6e-205 681.9 0.2 5.2e-205 681.7 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.27 CAR21423.1 - 1.7e-59 195.6 16.9 1.5e-08 34.1 0.0 10.7 12 0 0 12 12 12 9 WD domain, G-beta repeat eIF2A PF08662.6 CAR21423.1 - 0.047 13.4 1.4 3.2 7.3 0.0 3.6 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A PMT PF02366.13 CAR21424.1 - 5.9e-79 264.8 16.2 5.9e-79 264.8 11.2 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CAR21424.1 - 1.9e-23 82.9 1.4 3e-23 82.3 1.0 1.3 1 0 0 1 1 1 1 MIR domain TPR_17 PF13431.1 CAR21425.1 - 0.0003 20.7 0.9 1.3 9.3 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR21425.1 - 0.00048 20.4 1.9 0.059 13.7 0.1 4.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR21425.1 - 0.045 14.3 0.4 20 6.1 0.0 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAR21425.1 - 0.18 12.5 8.0 12 6.6 0.0 5.3 6 1 1 7 7 7 0 Tetratricopeptide repeat SUI1 PF01253.17 CAR21426.1 - 3.6e-21 74.7 3.1 3.6e-21 74.7 2.2 1.7 2 1 0 2 2 2 1 Translation initiation factor SUI1 PIN_2 PF10130.4 CAR21426.1 - 0.063 13.3 0.4 0.063 13.3 0.3 2.0 1 1 1 2 2 2 0 PIN domain TnpV PF14198.1 CAR21426.1 - 0.36 10.7 7.0 0.17 11.7 0.5 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Cgr1 PF03879.9 CAR21426.1 - 2.4 8.3 16.8 0.68 10.1 5.2 2.2 2 0 0 2 2 2 0 Cgr1 family RNase_PH PF01138.16 CAR21428.1 - 4.9e-29 101.3 0.2 6.7e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAR21428.1 - 2.4e-06 27.3 0.2 5.7e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.8 CAR21429.1 - 1.1e-79 267.7 22.6 1.1e-79 267.7 15.6 2.2 3 0 0 3 3 3 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 CAR21429.1 - 4.7e-07 29.5 11.3 4.7e-07 29.5 7.9 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) PIG-U PF06728.8 CAR21429.1 - 7.3e-06 25.0 34.9 1.3e-05 24.3 24.2 1.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Mito_carr PF00153.22 CAR21431.1 - 4.7e-52 173.6 3.0 4.6e-19 67.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein P_gingi_FimA PF06321.6 CAR21431.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Major fimbrial subunit protein (FimA) SPC12 PF06645.8 CAR21433.1 - 2.3e-18 65.7 0.0 2.6e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 CAR21433.1 - 0.01 14.5 0.7 0.012 14.3 0.5 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF1757 PF08560.5 CAR21433.1 - 0.026 14.2 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) PRA1 PF03208.14 CAR21433.1 - 0.032 13.5 0.1 0.034 13.4 0.1 1.1 1 0 0 1 1 1 0 PRA1 family protein SpecificRecomb PF10136.4 CAR21433.1 - 0.15 10.0 1.9 0.18 9.7 1.3 1.0 1 0 0 1 1 1 0 Site-specific recombinase FGGY_N PF00370.16 CAR21434.1 - 6.6e-26 91.1 0.0 1.8e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CAR21434.1 - 3.6e-16 59.3 0.0 3.5e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Biotin_lipoyl PF00364.17 CAR21435.1 - 3.3e-21 74.6 0.8 7.6e-21 73.5 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CAR21435.1 - 3.6e-06 26.5 0.0 9.4e-06 25.1 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CAR21435.1 - 0.0025 17.4 2.2 0.041 13.5 0.1 2.7 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.1 CAR21435.1 - 0.11 12.7 1.8 5.3 7.4 0.0 2.8 2 1 1 3 3 3 0 HlyD family secretion protein Endostatin PF06482.6 CAR21435.1 - 0.31 10.3 1.8 1 8.7 0.2 2.0 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin ATP-sulfurylase PF01747.12 CAR21436.1 - 9.1e-88 293.1 0.0 1.3e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CAR21436.1 - 9.3e-52 174.6 0.0 1.6e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Methyltransf_11 PF08241.7 CAR21437.1 - 2.8e-14 53.3 0.0 5.8e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR21437.1 - 1.9e-11 44.2 0.0 3.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR21437.1 - 5.3e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR21437.1 - 6.9e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR21437.1 - 2.1e-08 34.7 0.0 4.9e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR21437.1 - 3.1e-08 33.6 0.1 7.8e-08 32.3 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR21437.1 - 3.8e-08 33.0 0.0 6.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR21437.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 CAR21437.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 CAR21437.1 - 0.13 13.0 0.0 0.31 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Gp_dh_C PF02800.15 CAR21438.1 - 3.6e-74 247.4 0.1 5.3e-74 246.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CAR21438.1 - 1.4e-59 200.4 0.1 2.5e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CAR21438.1 - 0.038 13.9 0.6 0.12 12.2 0.1 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 CAR21438.1 - 0.055 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Memo PF01875.12 CAR21439.1 - 3.9e-86 288.3 0.1 4.5e-86 288.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein EIF_2_alpha PF07541.7 CAR21440.1 - 5.1e-41 138.9 0.8 9.2e-41 138.1 0.2 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CAR21440.1 - 1.6e-14 53.7 1.5 3e-14 52.8 1.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 CAR21440.1 - 0.09 12.7 0.7 0.2 11.6 0.2 1.9 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 Rap_GAP PF02145.10 CAR21441.1 - 2.9e-51 173.5 0.4 5.3e-51 172.6 0.3 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 CAR21441.1 - 1.6e-18 66.9 1.7 4.5e-16 58.8 0.2 2.3 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.3 CAR21441.1 - 2.5e-10 39.4 0.0 8.9e-10 37.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) AA_permease PF00324.16 CAR21442.1 - 1.6e-134 448.8 32.4 2e-134 448.5 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR21442.1 - 1.7e-40 138.8 35.2 2.1e-40 138.5 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_16 PF00722.16 CAR21443.1 - 1.3e-46 158.2 3.7 1.3e-46 158.2 2.5 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 FAM196 PF15265.1 CAR21443.1 - 3.6 6.6 23.8 4.8 6.3 16.5 1.1 1 0 0 1 1 1 0 FAM196 family RNA_pol_Rpb4 PF03874.11 CAR21444.1 - 9.4e-33 112.7 0.3 1.1e-32 112.4 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 VTC PF09359.5 CAR21445.1 - 4.8e-104 347.3 0.1 8e-104 346.6 0.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CAR21445.1 - 1.1e-21 77.9 15.9 7e-11 42.4 2.0 4.2 2 2 1 4 4 4 2 SPX domain DUF202 PF02656.10 CAR21445.1 - 9.9e-09 35.3 2.8 2.4e-08 34.0 2.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Mad3_BUB1_I PF08311.7 CAR21446.1 - 4.5e-42 142.7 0.9 9e-42 141.8 0.6 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 CAR21446.1 - 2.7e-26 91.2 0.0 8.6e-26 89.6 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 CAR21446.1 - 6.6e-21 74.6 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21446.1 - 4.7e-07 29.1 0.0 9.2e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Cpn60_TCP1 PF00118.19 CAR21447.1 - 1e-153 512.4 0.8 1.2e-153 512.2 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sad1_UNC PF07738.8 CAR21449.1 - 3.3e-07 30.1 0.0 8.4e-06 25.6 0.0 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal UPF0118 PF01594.11 CAR21449.1 - 0.26 10.2 0.5 0.92 8.4 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF20 Baculo_PEP_C PF04513.7 CAR21449.1 - 0.29 10.9 5.7 0.12 12.1 1.7 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bot1p PF12298.3 CAR21450.1 - 8.2e-60 201.6 0.5 1.1e-59 201.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Trs65 PF12735.2 CAR21451.1 - 5.8e-35 121.0 3.2 9.1e-35 120.4 2.2 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Clathrin_lg_ch PF01086.12 CAR21452.1 - 7e-63 212.5 27.5 7.9e-63 212.3 19.1 1.0 1 0 0 1 1 1 1 Clathrin light chain N2227 PF07942.7 CAR21453.1 - 0.15 10.9 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 N2227-like protein SH3_1 PF00018.23 CAR21454.1 - 1.6e-09 36.9 0.2 1.6e-09 36.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CAR21454.1 - 1.5e-07 30.8 0.0 3.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CAR21454.1 - 1.8e-07 30.6 0.2 4.4e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PseudoU_synth_2 PF00849.17 CAR21455.1 - 5e-31 107.7 0.1 1.1e-30 106.6 0.0 1.6 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF4355 PF14265.1 CAR21457.1 - 1.6 8.7 21.5 2.2 8.2 14.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) BTV_NS2 PF04514.7 CAR21457.1 - 1.8 7.3 10.0 2 7.1 7.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CAF-1_p150 PF11600.3 CAR21457.1 - 4.7 6.5 27.6 5.8 6.2 19.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 CAR21457.1 - 5.6 6.2 14.2 6.5 6.0 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 CAR21457.1 - 7.3 6.5 15.9 8.2 6.4 11.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1764 PF08576.5 CAR21457.1 - 7.8 7.3 11.4 11 6.8 7.9 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) PS_Dcarbxylase PF02666.10 CAR21458.1 - 2.7e-53 180.2 0.0 4.7e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CAR21458.1 - 6.2e-20 70.8 0.7 3.4e-10 39.6 0.1 2.8 2 0 0 2 2 2 2 C2 domain DNA_pol_E_B PF04042.11 CAR21459.1 - 7.4e-42 142.9 0.2 1.3e-41 142.1 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B tRNA-synt_1g PF09334.6 CAR21460.1 - 5.7e-109 364.3 0.0 7.9e-109 363.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CAR21460.1 - 1.9e-21 75.7 0.0 4.5e-10 38.1 0.0 3.2 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CAR21460.1 - 6e-10 38.7 0.0 0.00039 19.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CAR21460.1 - 0.0019 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Yip1 PF04893.12 CAR21461.1 - 2.3e-13 49.9 10.9 3.2e-13 49.5 7.5 1.2 1 0 0 1 1 1 1 Yip1 domain SdpI PF13630.1 CAR21461.1 - 0.11 12.1 0.1 0.11 12.1 0.0 2.4 1 1 2 3 3 3 0 SdpI/YhfL protein family TGS PF02824.16 CAR21462.1 - 1.3e-19 69.7 0.0 2.8e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CAR21462.1 - 6.3e-19 68.0 0.3 1.3e-18 67.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR21462.1 - 1e-12 47.6 0.0 1.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR21462.1 - 3.8e-05 23.5 0.4 0.0089 15.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 CAR21462.1 - 0.00032 21.1 0.0 0.0008 19.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CAR21462.1 - 0.0025 16.9 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MCM PF00493.18 CAR21462.1 - 0.0047 15.7 0.1 0.019 13.7 0.0 1.8 2 0 0 2 2 2 1 MCM2/3/5 family SRPRB PF09439.5 CAR21462.1 - 0.0058 15.8 0.6 0.027 13.7 0.1 2.2 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAR21462.1 - 0.073 12.4 1.9 8.3 5.8 0.1 3.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain NMT1 PF09084.6 CAR21463.1 - 8.4e-76 254.3 0.0 1e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 CAR21463.1 - 4.4e-07 29.5 0.2 0.028 13.7 0.0 2.8 2 1 1 3 3 3 2 NMT1-like family 2Fe-2S_thioredx PF01257.14 CAR21463.1 - 0.034 13.7 1.3 0.061 12.9 0.9 1.4 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Ribosomal_L24e PF01246.15 CAR21465.1 - 9.2e-29 99.1 2.3 2e-28 98.0 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 CAR21465.1 - 0.15 11.7 6.2 0.31 10.7 4.2 1.6 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Pam16 PF03656.8 CAR21466.1 - 2.3e-06 27.4 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 CAR21466.1 - 7.6e-06 25.5 0.1 1.3e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Yip1 PF04893.12 CAR21466.1 - 0.019 14.4 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain SMC_Nse1 PF07574.8 CAR21467.1 - 5e-42 143.8 0.0 6.2e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CAR21467.1 - 2e-07 30.8 11.1 3.6e-07 30.0 7.7 1.4 1 0 0 1 1 1 1 RING-like domain Response_reg PF00072.19 CAR21468.1 - 1.4e-20 73.3 0.1 1.9e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Adaptin_N PF01602.15 CAR21469.1 - 8.7e-98 327.9 10.0 1e-97 327.6 6.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region CMS1 PF14617.1 CAR21470.1 - 1.4e-15 57.1 11.2 2.7e-11 43.0 5.5 2.9 2 1 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit Dendrin PF15498.1 CAR21470.1 - 0.0067 14.9 3.6 0.01 14.4 2.5 1.2 1 0 0 1 1 1 1 Nephrin and CD2AP-binding protein, Dendrin VitD-bind_III PF09164.5 CAR21470.1 - 0.048 13.2 0.0 0.18 11.4 0.0 2.0 1 1 0 1 1 1 0 Vitamin D binding protein, domain III PolyA_pol_RNAbd PF12627.2 CAR21470.1 - 0.085 12.4 1.0 0.27 10.8 0.3 2.0 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A MFS_1 PF07690.11 CAR21471.1 - 2.3e-35 121.9 20.2 8.9e-35 120.0 14.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_92 PF07971.7 CAR21472.1 - 3.8e-138 461.2 1.3 5.1e-138 460.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ERAP1_C PF11838.3 CAR21472.1 - 0.15 11.2 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 ERAP1-like C-terminal domain Ssl1 PF04056.9 CAR21473.1 - 1.3e-88 295.6 0.1 1.8e-88 295.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 CAR21473.1 - 1.3e-22 79.5 12.2 1.3e-22 79.5 8.4 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 CAR21473.1 - 2.2e-14 53.9 0.0 3.2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CAR21473.1 - 2.8e-06 27.1 0.0 5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Taeniidae_ag PF05596.6 CAR21473.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 Taeniidae antigen IBR PF01485.16 CAR21473.1 - 5.8 6.8 21.7 0.022 14.6 4.9 2.9 2 1 0 2 2 2 0 IBR domain MFS_1 PF07690.11 CAR21474.1 - 4.2e-30 104.6 20.7 4.2e-30 104.6 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Candida_ALS_N PF11766.3 CAR21475.1 - 1.8e-59 200.6 4.5 1.8e-59 200.6 3.1 2.4 3 0 0 3 3 3 1 Cell-wall agglutinin N-terminal ligand-sugar binding TPR_8 PF13181.1 CAR21476.1 - 0.0055 16.3 0.7 6.4 6.8 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR21476.1 - 0.11 12.4 0.4 18 5.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CBF PF03914.12 CAR21478.1 - 6.4e-35 120.0 1.6 1.2e-34 119.1 0.1 2.3 2 1 1 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 CAR21478.1 - 6.5e-34 116.0 2.1 6.5e-34 116.0 1.4 3.1 2 1 1 3 3 3 1 Nucleolar complex-associated protein DUF502 PF04367.8 CAR21478.1 - 0.13 12.0 0.0 29 4.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF502) Mpp10 PF04006.7 CAR21479.1 - 5.2e-121 404.9 41.4 7.2e-121 404.4 28.7 1.2 1 0 0 1 1 1 1 Mpp10 protein Aa_trans PF01490.13 CAR21480.1 - 2.5e-74 250.1 23.8 3.2e-74 249.8 16.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.17 CAR21481.1 - 2.4e-15 55.9 0.1 3.5e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21481.1 - 2.5e-14 53.0 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR21481.1 - 5.2e-06 26.2 0.2 1.2e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.20 CAR21481.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain Fasciclin PF02469.17 CAR21482.1 - 2.1e-22 79.4 4.9 9.8e-08 32.0 0.0 5.8 5 1 0 5 5 5 5 Fasciclin domain Dynamin_M PF01031.15 CAR21483.1 - 1.2e-110 368.9 0.0 1.9e-110 368.2 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CAR21483.1 - 1.2e-52 178.1 0.0 4.2e-52 176.3 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CAR21483.1 - 1.7e-28 98.3 3.3 3.6e-28 97.3 1.3 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CAR21483.1 - 1.5e-05 24.9 0.4 0.00036 20.4 0.3 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR21483.1 - 0.017 15.5 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 CAR21483.1 - 0.1 11.8 0.1 7.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B KAT11 PF08214.6 CAR21484.1 - 2.4e-90 303.1 0.0 2.9e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 Histone acetylation protein Proteasome PF00227.21 CAR21485.1 - 1.4e-46 158.1 1.5 1.6e-46 157.9 1.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1_C PF10638.4 CAR21486.1 - 3.7e-26 91.6 2.9 1.7e-25 89.5 2.0 2.3 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Sfi1 PF08457.5 CAR21486.1 - 2.3e-20 72.5 82.1 2.3e-15 56.0 38.4 3.1 1 1 1 3 3 3 3 Sfi1 spindle body protein Ribophorin_I PF04597.9 CAR21487.1 - 5.3e-125 417.3 0.4 6e-125 417.1 0.3 1.0 1 0 0 1 1 1 1 Ribophorin I ORC3_N PF07034.6 CAR21488.1 - 4.9e-08 32.3 1.8 4.9e-08 32.3 1.2 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Sir1 PF11603.3 CAR21488.1 - 0.25 11.5 4.3 0.24 11.5 1.4 2.1 2 0 0 2 2 2 0 Regulatory protein Sir1 COX16 PF14138.1 CAR21489.1 - 7.6e-32 109.3 0.2 7.6e-32 109.3 0.1 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 MFS_1 PF07690.11 CAR21489.1 - 0.087 11.5 0.1 0.11 11.1 0.1 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF221 PF02714.10 CAR21490.1 - 3.4e-84 282.5 24.2 8.3e-84 281.2 16.8 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CAR21490.1 - 6.2e-32 110.3 1.0 6.2e-32 110.3 0.7 3.4 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CAR21490.1 - 0.0011 18.8 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CAR21490.1 - 0.13 12.8 5.7 3.5 8.1 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DUF2404 PF10296.4 CAR21491.1 - 9.1e-06 25.7 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF3571 PF12095.3 CAR21491.1 - 0.019 15.1 0.5 1.3 9.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3571) DEAD PF00270.24 CAR21493.1 - 7.5e-45 152.4 0.3 2.6e-44 150.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR21493.1 - 7.6e-25 86.5 0.0 2e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAR21493.1 - 0.027 14.5 0.1 0.09 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain SYS1 PF09801.4 CAR21494.1 - 1.5e-46 158.0 12.9 1.8e-46 157.7 8.9 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PP2C PF00481.16 CAR21495.1 - 9.5e-54 182.4 0.0 2e-53 181.3 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 CAR21495.1 - 6.7e-46 153.2 106.1 1.4e-09 37.3 1.2 12.9 7 3 5 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR21495.1 - 1.5e-41 139.9 86.1 6.8e-09 35.3 3.3 9.6 5 2 4 10 10 10 9 Leucine rich repeat Guanylate_cyc PF00211.15 CAR21495.1 - 5e-27 94.4 0.0 9.7e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CAR21495.1 - 1.1e-16 58.2 87.7 0.076 13.0 0.1 19.2 17 1 0 17 17 17 11 Leucine Rich Repeat RA PF00788.18 CAR21495.1 - 2.9e-08 34.0 0.1 6.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 CAR21495.1 - 9.8e-08 31.0 72.6 0.51 10.7 0.1 17.9 17 1 1 18 18 18 5 Leucine rich repeat LRR_6 PF13516.1 CAR21495.1 - 0.00036 20.3 87.8 0.46 10.6 1.4 17.8 16 2 2 18 18 18 5 Leucine Rich repeat PNP_UDP_1 PF01048.15 CAR21496.1 - 1.1e-34 119.5 0.0 1.2e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NPCC PF08058.6 CAR21497.1 - 4.2e-31 107.7 1.0 6.5e-31 107.1 0.7 1.2 1 0 0 1 1 1 1 Nuclear pore complex component NIF PF03031.13 CAR21498.1 - 3.2e-49 166.6 0.2 4.8e-49 166.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.27 CAR21499.1 - 4.6e-36 121.4 2.0 8.8e-09 34.9 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 CAR21499.1 - 3.7e-29 100.5 11.2 9.8e-29 99.2 7.8 1.8 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 CAR21499.1 - 0.00049 19.8 0.4 0.023 14.4 0.0 3.7 4 2 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Abhydro_lipase PF04083.11 CAR21500.1 - 4.8e-15 54.6 0.0 9.5e-15 53.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CAR21500.1 - 3.3e-06 27.1 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR21500.1 - 0.0009 18.8 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 CAR21500.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) chaperone_DMP PF10448.4 CAR21501.1 - 1.3e-30 106.1 0.0 1.5e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone SBDS_C PF09377.5 CAR21502.1 - 2.6e-37 127.2 0.6 2.6e-37 127.2 0.4 1.7 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 CAR21502.1 - 7e-31 105.8 5.4 1e-30 105.3 3.7 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HlyIII PF03006.15 CAR21503.1 - 3.8e-55 186.6 16.7 3.8e-55 186.6 11.6 1.5 2 0 0 2 2 2 1 Haemolysin-III related PUF PF00806.14 CAR21504.1 - 8.7e-51 166.6 10.0 2e-07 30.1 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.7 CAR21505.1 - 7.7e-17 61.1 5.0 9.4e-17 60.9 3.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.9 CAR21506.1 - 9.7e-70 234.0 2.0 1e-69 233.9 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CAR21506.1 - 1.1e-22 79.3 0.7 3.5e-22 77.7 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 CAR21506.1 - 0.048 13.9 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats TFIIF_alpha PF05793.7 CAR21507.1 - 7.1e-10 37.8 0.2 7.1e-10 37.8 0.1 3.3 1 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1b PF00579.20 CAR21508.1 - 7.2e-74 248.5 0.0 9.3e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.15 CAR21509.1 - 4.8e-13 48.6 9.4 4.8e-13 48.6 6.5 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ZZ PF00569.12 CAR21509.1 - 0.047 13.2 7.8 0.17 11.4 5.4 2.1 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-UBR PF02207.15 CAR21510.1 - 1.5e-17 63.0 14.8 1.5e-17 63.0 10.3 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CAR21510.1 - 1.4e-07 31.1 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 CAR21510.1 - 0.00013 21.7 0.7 0.00013 21.7 0.5 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAR21510.1 - 0.0075 16.2 1.3 0.0075 16.2 0.9 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) GP38 PF05268.6 CAR21510.1 - 0.011 15.1 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 UCR_UQCRX_QCR9 PF05365.7 CAR21511.1 - 7.2e-27 92.7 3.3 8.1e-27 92.6 2.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-Tim10_DDP PF02953.10 CAR21512.1 - 4.4e-19 67.5 1.5 7e-19 66.8 1.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 CAR21512.1 - 0.047 13.5 0.6 0.12 12.2 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) Clat_adaptor_s PF01217.15 CAR21513.1 - 4.5e-56 188.5 0.9 5.4e-56 188.2 0.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CBP4 PF07960.6 CAR21514.1 - 2.1e-50 169.6 4.9 2.5e-50 169.3 3.4 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 CAR21514.1 - 0.0034 17.0 2.2 0.0084 15.8 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4574) XH PF03469.9 CAR21514.1 - 0.0038 16.8 4.6 0.0052 16.4 3.2 1.2 1 0 0 1 1 1 1 XH domain UPF0449 PF15136.1 CAR21514.1 - 0.044 13.9 3.6 0.035 14.2 1.6 1.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 CAF-1_p150 PF11600.3 CAR21514.1 - 0.12 11.6 12.7 0.16 11.3 8.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMEM51 PF15345.1 CAR21514.1 - 0.16 11.6 2.7 0.2 11.3 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Imm42 PF15601.1 CAR21514.1 - 0.55 9.6 6.5 0.15 11.4 0.5 2.0 1 1 1 2 2 2 0 Immunity protein 42 DDHD PF02862.12 CAR21514.1 - 2 8.1 6.2 2.5 7.8 4.3 1.0 1 0 0 1 1 1 0 DDHD domain SE PF08491.5 CAR21515.1 - 5.1e-123 409.2 0.0 6.5e-123 408.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CAR21515.1 - 7.3e-13 48.2 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CAR21515.1 - 1.3e-06 27.5 0.1 0.00012 21.1 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAR21515.1 - 0.0014 18.5 0.3 0.0042 16.9 0.1 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAR21515.1 - 0.0042 16.2 0.0 0.0089 15.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CAR21515.1 - 0.0088 16.0 0.1 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CAR21515.1 - 0.013 15.8 0.1 0.043 14.2 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CAR21515.1 - 0.046 12.6 0.3 0.81 8.5 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 CAR21515.1 - 0.063 12.1 1.1 0.097 11.4 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain GDI PF00996.13 CAR21515.1 - 0.098 10.9 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 CAR21515.1 - 0.12 11.9 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CAR21515.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 CAR21515.1 - 0.35 9.9 0.6 1.2 8.0 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase AATase PF07247.7 CAR21516.1 - 1e-117 393.6 0.0 1.2e-117 393.4 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CAR21516.1 - 0.09 11.6 0.1 0.87 8.3 0.0 2.4 3 0 0 3 3 3 0 Condensation domain RRN7 PF11781.3 CAR21517.1 - 1.1e-10 40.8 1.0 2.1e-10 39.9 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 LsmAD PF06741.8 CAR21518.1 - 7.2e-31 106.1 0.3 2e-30 104.6 0.2 1.8 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 CAR21518.1 - 2.9e-14 52.7 0.4 6.7e-14 51.5 0.0 1.9 2 0 0 2 2 2 1 Ataxin 2 SM domain CENP-Q PF13094.1 CAR21519.1 - 0.0039 17.2 5.3 0.012 15.6 3.6 1.9 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit His_leader PF08047.6 CAR21519.1 - 0.83 9.1 3.8 1.6 8.2 2.6 1.4 1 0 0 1 1 1 0 Histidine operon leader peptide MFS_1 PF07690.11 CAR21520.1 - 2.5e-36 125.1 28.5 2.5e-36 125.1 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR21520.1 - 1.6e-12 46.7 23.0 2.4e-12 46.1 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CAR21520.1 - 4.2e-10 38.4 1.3 6.4e-10 37.8 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Thi4 PF01946.12 CAR21521.1 - 2.4e-97 324.5 0.1 2.8e-97 324.3 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CAR21521.1 - 2.8e-07 29.7 0.0 4.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAR21521.1 - 1.3e-05 25.0 0.1 5.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CAR21521.1 - 4.4e-05 22.4 0.8 0.00016 20.6 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CAR21521.1 - 9.4e-05 22.2 0.1 0.00071 19.3 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CAR21521.1 - 9.4e-05 21.4 0.3 0.00014 20.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CAR21521.1 - 0.0015 18.4 0.3 0.0015 18.4 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR21521.1 - 0.01 15.9 0.1 0.032 14.2 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAR21521.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CAR21521.1 - 0.015 13.7 0.5 0.028 12.8 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 CAR21521.1 - 0.049 12.4 0.2 0.076 11.8 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 CAR21521.1 - 0.065 11.8 0.2 0.088 11.4 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Ribonuc_red_sm PF00268.16 CAR21522.1 - 8.5e-121 402.2 3.6 1.1e-120 401.9 2.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NDK PF00334.14 CAR21524.1 - 1e-55 187.2 0.0 1.1e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SRF-TF PF00319.13 CAR21525.1 - 9.8e-24 82.3 0.2 1.3e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Sporozoite_P67 PF05642.6 CAR21525.1 - 0.00068 17.6 1.8 0.0007 17.5 1.2 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 CAR21525.1 - 0.0011 18.4 0.4 0.0016 17.9 0.3 1.4 1 0 0 1 1 1 1 Nucleoplasmin Spt5_N PF11942.3 CAR21525.1 - 0.0025 18.4 7.7 0.0025 18.4 5.4 1.6 2 0 0 2 2 1 1 Spt5 transcription elongation factor, acidic N-terminal AF1Q PF15017.1 CAR21525.1 - 0.028 14.3 3.4 0.028 14.3 2.4 2.0 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator Zip PF02535.17 CAR21525.1 - 0.042 12.8 2.5 0.05 12.5 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop53 PF07767.6 CAR21525.1 - 0.045 12.7 6.3 0.076 11.9 4.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2890 PF11081.3 CAR21525.1 - 0.52 10.3 6.5 0.93 9.5 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 CAR21525.1 - 0.54 8.6 10.7 0.77 8.1 7.4 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CAR21525.1 - 1.3 8.2 8.8 2.1 7.5 6.1 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 CAR21525.1 - 1.4 6.8 12.9 0.27 9.2 6.3 1.6 1 1 1 2 2 2 0 CDC45-like protein eIF-3c_N PF05470.7 CAR21525.1 - 2.7 5.9 9.3 3.7 5.5 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.8 CAR21525.1 - 2.8 7.5 9.7 0.28 10.7 3.7 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region YL1 PF05764.8 CAR21525.1 - 3.5 7.1 10.4 0.86 9.1 3.4 2.0 2 0 0 2 2 2 0 YL1 nuclear protein DUF2486 PF10667.4 CAR21525.1 - 5.6 7.4 21.2 7.8 6.9 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Bd3614_N PF14442.1 CAR21525.1 - 6.9 6.6 6.8 13 5.7 4.7 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal CENP-B_dimeris PF09026.5 CAR21525.1 - 6.9 6.9 17.0 14 5.9 11.8 1.5 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Lin-8 PF03353.10 CAR21525.1 - 7 5.8 13.2 11 5.2 9.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Herpes_DNAp_acc PF04929.7 CAR21525.1 - 8.9 5.1 9.6 16 4.3 6.7 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PWWP PF00855.12 CAR21526.1 - 9.1e-19 67.4 1.1 1.2e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 PWWP domain Nucleoporin_FG PF13634.1 CAR21527.1 - 5.5e-84 277.9 431.4 9.8e-17 61.2 32.0 12.6 4 2 7 11 11 11 9 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 CAR21527.1 - 6.9e-46 155.5 0.0 1.1e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Swi3 PF07962.7 CAR21528.1 - 1.3e-29 101.6 0.2 1.9e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DUF3245 PF11595.3 CAR21528.1 - 0.23 11.7 2.8 0.41 10.9 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) CLPTM1 PF05602.7 CAR21529.1 - 1e-76 258.4 0.1 1.3e-76 258.0 0.1 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) BOP1NT PF08145.7 CAR21530.1 - 3.2e-103 344.9 8.8 6e-103 344.0 6.1 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CAR21530.1 - 9.7e-30 101.3 6.5 2e-11 43.2 0.2 7.6 7 1 0 7 7 7 4 WD domain, G-beta repeat GAF_2 PF13185.1 CAR21531.1 - 1.3e-08 35.4 0.0 1.7e-08 35.0 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 CAR21531.1 - 4e-05 23.7 0.0 5.2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 GAF domain DUF1413 PF07205.6 CAR21532.1 - 0.01 15.3 0.3 1.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) DUF327 PF03885.8 CAR21532.1 - 0.03 14.1 2.4 0.028 14.2 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF327) Sulfotransfer_1 PF00685.22 CAR21532.1 - 0.054 12.7 0.6 0.1 11.8 0.2 1.7 1 1 0 1 1 1 0 Sulfotransferase domain DUF2205 PF10224.4 CAR21532.1 - 2 8.0 9.5 0.27 10.8 1.3 3.3 1 1 3 4 4 4 0 Predicted coiled-coil protein (DUF2205) CENP-F_leu_zip PF10473.4 CAR21533.1 - 0.0082 16.0 5.4 0.016 15.0 3.7 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lectin_N PF03954.9 CAR21533.1 - 0.072 12.4 1.8 0.11 11.8 0.2 2.2 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DASH_Dam1 PF08653.5 CAR21533.1 - 0.22 11.3 1.3 0.63 9.8 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Cortex-I_coil PF09304.5 CAR21533.1 - 0.45 10.5 7.4 0.27 11.2 1.9 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 CAR21534.1 - 2e-279 928.6 5.7 2.3e-279 928.4 4.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 CAR21534.1 - 0.03 14.1 0.8 4.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 CAR21534.1 - 0.13 12.3 0.6 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 CAR21534.1 - 0.43 10.4 1.8 6.5 6.6 0.1 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HSP70 PF00012.15 CAR21535.1 - 3.6e-51 173.8 6.0 9.8e-50 169.0 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein TP_methylase PF00590.15 CAR21535.1 - 0.046 13.4 0.0 0.16 11.6 0.0 1.9 1 1 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases RRM_5 PF13893.1 CAR21536.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR21536.1 - 0.00047 19.7 0.1 0.0019 17.7 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21536.1 - 0.027 14.4 0.0 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CAR21536.1 - 0.1 12.1 0.1 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Calcipressin RabGAP-TBC PF00566.13 CAR21537.1 - 5.3e-34 117.5 0.0 7.5e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cu-oxidase_2 PF07731.9 CAR21538.1 - 4e-45 152.7 8.0 1.8e-38 131.1 0.6 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CAR21538.1 - 1.9e-44 150.1 3.8 1.5e-40 137.6 0.4 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 CAR21538.1 - 2.4e-31 108.8 10.2 3e-30 105.2 1.8 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.1 CAR21538.1 - 0.025 14.4 0.0 4.2 7.3 0.0 3.4 3 0 0 3 3 3 0 Cupredoxin-like domain C1q PF00386.16 CAR21538.1 - 0.07 13.1 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 C1q domain Self-incomp_S1 PF05938.6 CAR21538.1 - 0.09 12.9 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 DUF4448 PF14610.1 CAR21540.1 - 8.1e-59 198.3 0.2 1.2e-58 197.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Sen15 PF09631.5 CAR21541.1 - 6.8e-28 96.8 0.0 7.7e-28 96.6 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein Tom37_C PF11801.3 CAR21542.1 - 1.2e-37 129.3 1.0 1.6e-37 128.9 0.7 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 CAR21542.1 - 2.4e-22 78.9 0.0 4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Suf PF05843.9 CAR21543.1 - 1.1e-72 245.1 11.7 4.6e-63 213.5 2.3 4.7 5 1 1 6 6 6 3 Suppressor of forked protein (Suf) Latarcin PF10279.4 CAR21543.1 - 0.00018 21.6 0.2 0.31 11.2 0.0 3.5 3 0 0 3 3 3 2 Latarcin precursor TPR_14 PF13428.1 CAR21543.1 - 0.011 16.2 0.0 0.48 11.2 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR21543.1 - 0.043 14.2 0.3 0.65 10.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat P4Ha_N PF08336.6 CAR21543.1 - 0.061 13.1 0.4 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ArgJ PF01960.13 CAR21544.1 - 5.6e-144 479.3 5.4 6.4e-144 479.1 3.7 1.0 1 0 0 1 1 1 1 ArgJ family K-cyclin_vir_C PF09080.5 CAR21544.1 - 0.13 12.5 0.7 0.52 10.5 0.1 2.3 2 0 0 2 2 2 0 K cyclin, C terminal Sugar_tr PF00083.19 CAR21545.1 - 1.4e-109 366.7 19.0 1.7e-109 366.3 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR21545.1 - 1.5e-21 76.5 14.1 1.5e-21 76.5 9.8 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily OppC_N PF12911.2 CAR21545.1 - 3.5 7.0 8.5 0.85 9.0 0.1 3.5 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C zf-B_box PF00643.19 CAR21546.1 - 0.049 13.5 4.4 0.049 13.5 3.1 2.4 2 0 0 2 2 2 0 B-box zinc finger IRF-2BP1_2 PF11261.3 CAR21546.1 - 0.2 11.1 4.2 0.42 10.0 1.8 2.1 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger ANTH PF07651.11 CAR21547.1 - 2.7e-66 223.1 1.0 5.5e-66 222.1 0.7 1.5 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 CAR21547.1 - 2.7e-07 30.4 0.4 1.2e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 ENTH domain PFK PF00365.15 CAR21548.1 - 7.9e-170 563.1 3.0 7.6e-127 422.0 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 CAR21548.1 - 0.18 11.3 0.4 0.41 10.2 0.3 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Tht1 PF04163.7 CAR21549.1 - 2.1e-45 155.1 6.6 2.6e-45 154.8 4.5 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein SPAM PF02090.10 CAR21549.1 - 0.019 14.9 1.5 25 4.8 0.0 3.3 3 0 0 3 3 3 0 Salmonella surface presentation of antigen gene type M protein Baculo_PEP_C PF04513.7 CAR21549.1 - 1.2 8.9 6.2 5.2 6.8 0.3 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SUR7 PF06687.7 CAR21551.1 - 4.2e-29 101.6 14.3 5.3e-29 101.3 9.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family CobD_Cbib PF03186.8 CAR21551.1 - 0.0036 16.4 2.9 0.004 16.2 1.0 1.7 2 0 0 2 2 2 1 CobD/Cbib protein DUF2207 PF09972.4 CAR21551.1 - 0.094 11.2 1.9 0.13 10.8 1.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF912 PF06024.7 CAR21551.1 - 0.66 10.0 0.0 0.66 10.0 0.0 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4191 PF13829.1 CAR21551.1 - 1.5 7.9 3.4 2.4 7.2 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) HA2 PF04408.18 CAR21552.1 - 1.9e-19 69.5 0.1 4.4e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR21552.1 - 3.3e-17 62.3 0.0 8.6e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAR21552.1 - 7e-11 41.8 0.0 2.6e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR21552.1 - 1.4e-09 37.6 0.1 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR21552.1 - 3.9e-07 30.2 0.1 7.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CAR21552.1 - 0.0014 18.0 0.0 0.0039 16.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 CAR21552.1 - 0.0048 16.8 0.2 0.045 13.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAR21552.1 - 0.0061 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_11 PF13086.1 CAR21552.1 - 0.0068 15.9 0.4 0.044 13.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 CAR21552.1 - 0.016 14.6 0.0 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 CAR21552.1 - 0.029 14.1 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 CAR21552.1 - 0.03 13.2 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1903 PF08991.5 CAR21552.1 - 0.03 14.4 0.4 0.065 13.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) ResIII PF04851.10 CAR21552.1 - 0.033 14.0 0.2 0.38 10.5 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CAR21552.1 - 0.037 13.2 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF258 PF03193.11 CAR21552.1 - 0.046 12.9 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.17 CAR21552.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Ras family KaiC PF06745.8 CAR21552.1 - 0.091 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CAR21552.1 - 0.19 12.0 1.5 0.67 10.2 1.1 1.9 1 1 0 1 1 1 0 AAA domain Glu_synthase PF01645.12 CAR21554.1 - 1.2e-155 517.9 0.1 2.9e-155 516.7 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CAR21554.1 - 5.7e-138 459.5 0.0 1.2e-137 458.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CAR21554.1 - 1.2e-117 392.2 0.0 7.1e-116 386.4 0.0 3.0 3 0 0 3 3 3 1 Glutamate synthase central domain GXGXG PF01493.14 CAR21554.1 - 6.6e-58 195.0 0.7 1.3e-57 194.0 0.5 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CAR21554.1 - 4e-23 81.1 0.1 8e-23 80.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CAR21554.1 - 2e-14 53.9 0.1 9e-14 51.8 0.1 2.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR21554.1 - 5.3e-09 35.9 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAR21554.1 - 2e-08 34.5 0.7 0.0023 18.0 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR21554.1 - 1.2e-06 28.8 0.2 0.00013 22.2 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAR21554.1 - 3.8e-06 26.0 0.2 3.2e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 CAR21554.1 - 5.8e-06 25.6 0.1 1.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 CAR21554.1 - 5.2e-05 21.8 1.5 5.6e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 CAR21554.1 - 0.00039 19.3 0.0 0.00074 18.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CAR21554.1 - 0.00039 19.6 0.1 0.00071 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AdoHcyase_NAD PF00670.16 CAR21554.1 - 0.0042 16.9 1.3 4 7.2 0.0 3.6 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Thi4 PF01946.12 CAR21554.1 - 0.0055 15.8 0.4 0.02 13.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 CAR21554.1 - 0.0084 15.2 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GATase_6 PF13522.1 CAR21554.1 - 0.0087 16.0 0.0 0.03 14.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain NAD_Gly3P_dh_N PF01210.18 CAR21554.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 CAR21554.1 - 0.015 15.5 0.8 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 CAR21554.1 - 0.097 12.4 0.0 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 CAR21554.1 - 2.1 7.1 6.2 0.18 10.6 0.1 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF3602 PF12223.3 CAR21555.1 - 2.4e-21 75.9 14.6 2.9e-13 49.9 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) eIF3_subunit PF08597.5 CAR21556.1 - 6.1e-64 215.9 13.0 8.8e-64 215.3 9.0 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit FAD-oxidase_C PF02913.14 CAR21557.1 - 6.2e-56 189.4 0.4 1.5e-55 188.2 0.1 1.8 3 0 0 3 3 3 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAR21557.1 - 4.4e-37 126.6 0.0 1.4e-36 125.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain LEA_4 PF02987.11 CAR21558.1 - 0.00037 20.3 52.9 0.0038 17.0 9.6 5.0 2 1 1 4 4 4 3 Late embryogenesis abundant protein YtxH PF12732.2 CAR21558.1 - 0.011 16.0 32.5 0.96 9.8 7.5 4.1 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.8 CAR21558.1 - 0.011 16.0 29.2 0.095 13.1 6.0 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Borrelia_P83 PF05262.6 CAR21558.1 - 1.7 6.8 33.0 2 6.5 22.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP-synt_B PF00430.13 CAR21558.1 - 2 8.1 35.3 0.054 13.2 9.5 2.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Peroxin-13_N PF04088.8 CAR21559.1 - 3.1e-53 179.9 3.5 4.5e-53 179.4 2.4 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 CAR21559.1 - 1.4e-10 40.5 0.1 5.8e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CAR21559.1 - 1.1e-09 37.5 0.0 6.8e-09 35.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CAR21559.1 - 2.2e-08 33.3 0.0 4.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 CAR21559.1 - 0.00079 19.5 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Arfaptin PF06456.8 CAR21559.1 - 0.21 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain MMR1 PF08505.5 CAR21560.1 - 6.3e-77 258.7 11.6 6.3e-77 258.7 8.0 2.2 2 1 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein DUF342 PF03961.8 CAR21560.1 - 0.078 11.3 3.5 0.12 10.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Med9 PF07544.8 CAR21560.1 - 0.47 10.2 6.6 6 6.6 4.6 2.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 YlqD PF11068.3 CAR21560.1 - 0.7 9.9 10.4 1.7 8.6 7.2 1.6 1 0 0 1 1 1 0 YlqD protein TMF_DNA_bd PF12329.3 CAR21560.1 - 1.1 9.1 12.0 0.17 11.6 2.4 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 CAR21560.1 - 1.8 8.5 8.9 14 5.7 2.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 CAR21560.1 - 7.2 6.1 9.8 14 5.2 1.9 2.5 2 0 0 2 2 2 0 Septum formation initiator FlxA PF14282.1 CAR21560.1 - 9.1 6.2 18.7 0.14 12.1 1.3 3.3 2 1 1 3 3 3 0 FlxA-like protein PALP PF00291.20 CAR21561.1 - 4.6e-75 252.6 0.2 5.8e-75 252.3 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CAR21561.1 - 4e-41 138.5 0.1 1.4e-27 95.0 0.0 2.6 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase tRNA-synt_2b PF00587.20 CAR21562.1 - 2.8e-30 105.1 0.0 4.4e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR21562.1 - 0.0022 17.8 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Sec61_beta PF03911.11 CAR21563.1 - 6.8e-18 64.1 0.4 8.2e-18 63.9 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family Cas_Csx9 PF09658.5 CAR21563.1 - 0.019 13.8 0.0 0.021 13.6 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) RRM_6 PF14259.1 CAR21564.1 - 7.7e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR21564.1 - 2.4e-06 27.0 0.1 5.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR21564.1 - 2.2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_N PF08240.7 CAR21565.1 - 7.2e-26 90.0 3.3 1.3e-25 89.2 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR21565.1 - 1.8e-18 66.3 0.0 2.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CAR21565.1 - 4.4e-05 22.7 0.0 7.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CAR21565.1 - 0.032 13.6 0.1 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 CAR21565.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CAR21565.1 - 0.093 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RseC_MucC PF04246.7 CAR21565.1 - 0.31 10.6 1.3 0.64 9.5 0.9 1.5 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC MOZ_SAS PF01853.13 CAR21566.1 - 2.5e-79 264.9 0.4 3.9e-79 264.2 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-C2H2 PF00096.21 CAR21566.1 - 1.1 9.7 3.6 4.6 7.7 2.5 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type Myb_DNA-bind_6 PF13921.1 CAR21567.1 - 4.8e-10 39.3 2.0 2.2e-09 37.2 0.2 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CAR21567.1 - 1.5e-06 28.1 1.4 3.6e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.1 CAR21568.1 - 1.3e-35 122.3 0.0 2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease IFP_35_N PF07334.8 CAR21569.1 - 9.7 6.2 14.0 0.6 10.1 0.2 3.1 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus NMT1 PF09084.6 CAR21570.1 - 2.5e-12 46.8 0.0 4.4e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 NMT1/THI5 like SBP_bac_3 PF00497.15 CAR21570.1 - 2.1e-08 33.7 0.0 3.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.1 CAR21570.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.2 CAR21570.1 - 5.3e-06 25.9 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.15 CAR21570.1 - 0.063 12.3 0.0 0.17 10.9 0.0 1.7 1 1 0 1 1 1 0 LysR substrate binding domain DCP2 PF05026.8 CAR21571.1 - 1.6e-32 111.2 1.3 3.4e-32 110.1 0.9 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CAR21571.1 - 1.1e-12 47.7 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain SUZ PF12752.2 CAR21571.1 - 0.038 14.5 5.0 1 9.9 0.0 4.6 4 1 1 5 5 5 0 SUZ domain DUF2392 PF10288.4 CAR21572.1 - 1.2e-29 102.8 0.0 4.2e-29 101.0 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) zf-CDGSH PF09360.5 CAR21572.1 - 0.021 14.6 2.8 0.03 14.1 0.5 2.2 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type DUF1903 PF08991.5 CAR21573.1 - 7e-06 26.1 4.8 1.1e-05 25.4 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CAR21573.1 - 4.6e-05 23.2 10.4 6.8e-05 22.6 7.2 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CAR21573.1 - 0.02 14.9 4.5 0.032 14.2 3.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 CAR21573.1 - 0.33 10.8 6.5 1.2 9.0 3.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) TPR_11 PF13414.1 CAR21574.1 - 2.8e-40 135.7 14.1 7e-16 57.6 0.0 6.8 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 CAR21574.1 - 1.7e-27 93.8 15.1 7.1e-07 28.5 0.2 10.0 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 CAR21574.1 - 2e-25 86.5 23.4 0.00038 20.1 0.1 11.7 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 CAR21574.1 - 9e-25 86.7 13.1 1.8e-05 25.2 0.1 7.1 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CAR21574.1 - 5.9e-18 64.5 13.2 0.0039 17.0 0.0 7.5 4 3 6 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 CAR21574.1 - 1.8e-14 52.9 15.3 0.092 13.4 0.0 9.4 4 3 6 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAR21574.1 - 1.5e-13 49.7 8.4 0.75 10.1 0.0 9.1 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR21574.1 - 7e-13 48.7 18.0 4.2e-06 26.9 1.5 6.7 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAR21574.1 - 2.8e-12 45.4 25.0 0.026 14.2 0.1 9.3 9 1 1 10 10 9 4 Tetratricopeptide repeat Apc3 PF12895.2 CAR21574.1 - 1.1e-06 28.6 11.2 0.026 14.6 0.2 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CAR21574.1 - 2e-06 27.5 0.4 10 6.0 0.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 CAR21574.1 - 0.0025 16.9 3.7 0.069 12.2 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR21574.1 - 0.0027 17.3 13.1 0.19 11.6 0.2 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF3366 PF11846.3 CAR21574.1 - 0.04 13.8 0.2 6.4 6.5 0.0 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF3366) Exonuc_VII_S PF02609.11 CAR21574.1 - 0.048 13.4 3.5 0.079 12.7 0.3 2.9 2 0 0 2 2 2 0 Exonuclease VII small subunit TPR_6 PF13174.1 CAR21574.1 - 0.11 12.9 26.9 8.3 7.1 0.4 9.0 10 0 0 10 10 8 0 Tetratricopeptide repeat MIT PF04212.13 CAR21574.1 - 0.18 11.7 5.4 4.3 7.3 0.1 4.6 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 CAR21574.1 - 0.32 11.1 9.2 0.26 11.4 1.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L35p PF01632.14 CAR21576.1 - 7.4e-07 28.9 4.4 1.1e-06 28.4 3.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 PDZ_1 PF12812.2 CAR21577.1 - 8.8e-51 169.7 0.1 1.4e-33 114.6 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 CAR21577.1 - 1.4e-14 54.1 0.3 5.1e-11 42.6 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.1 CAR21577.1 - 1.6e-13 50.2 3.9 6.5e-05 22.7 0.1 4.8 5 0 0 5 5 5 2 PDZ domain PDZ PF00595.19 CAR21577.1 - 5.1e-10 39.3 0.0 5e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 CAR21577.1 - 5.2e-05 22.9 0.0 0.0002 21.0 0.0 2.0 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 CAR21577.1 - 0.003 17.2 0.6 0.074 12.8 0.0 3.3 5 0 0 5 5 5 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 CAR21577.1 - 0.015 14.7 0.1 0.031 13.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 CAR21577.1 - 0.015 14.6 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 CAR21577.1 - 0.13 10.6 0.3 0.47 8.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase S46 ORC6 PF05460.8 CAR21578.1 - 4.8e-84 282.4 1.7 5.4e-84 282.2 1.2 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) N-SET PF11764.3 CAR21579.1 - 3.5e-40 137.6 1.3 3.5e-40 137.6 0.9 2.7 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 CAR21579.1 - 9.8e-24 84.4 0.1 9.8e-24 84.4 0.1 3.7 3 2 0 3 3 3 1 SET domain SET_assoc PF11767.3 CAR21579.1 - 5.1e-17 60.9 0.1 1.1e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated MutS_V PF00488.16 CAR21580.1 - 2.3e-77 259.5 0.0 4e-77 258.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR21580.1 - 5.9e-37 127.4 3.2 1.5e-36 126.1 2.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CAR21580.1 - 7.3e-28 96.8 0.0 2.4e-27 95.2 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CAR21580.1 - 2.4e-09 37.3 0.0 1.2e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 MutS domain II AAA_14 PF13173.1 CAR21580.1 - 0.017 15.0 0.0 0.062 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CAR21580.1 - 0.054 13.7 0.2 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 ABC transporter DUF2629 PF10945.3 CAR21580.1 - 0.09 12.1 0.1 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2629) AAA_23 PF13476.1 CAR21580.1 - 0.52 10.6 4.0 0.57 10.4 0.0 2.6 2 1 1 3 3 3 0 AAA domain Gar1 PF04410.9 CAR21581.1 - 3.3e-47 159.8 0.1 1.9e-46 157.3 0.0 2.2 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region PAT1 PF09770.4 CAR21581.1 - 7.8 4.5 45.5 12 3.9 31.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spc97_Spc98 PF04130.8 CAR21582.1 - 5.1e-67 226.4 16.5 5.1e-67 226.4 11.4 1.8 1 1 1 2 2 2 1 Spc97 / Spc98 family DUF3402 PF11882.3 CAR21583.1 - 2.5e-86 290.3 10.8 1.4e-84 284.4 7.5 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CAR21583.1 - 5.5e-64 215.8 1.0 5.5e-64 215.8 0.7 2.0 3 0 0 3 3 3 1 N1221-like protein ApoO PF09769.4 CAR21584.1 - 0.068 12.8 0.3 0.091 12.4 0.2 1.3 1 1 0 1 1 1 0 Apolipoprotein O DSPc PF00782.15 CAR21585.1 - 6.2e-11 42.0 0.0 2.1e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR21585.1 - 0.00043 19.7 0.0 0.00089 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CAR21585.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family AAA_18 PF13238.1 CAR21586.1 - 6.1e-07 29.8 0.0 7e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR21586.1 - 2.1e-06 28.5 0.0 3.3e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CAR21586.1 - 2.6e-06 27.1 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 CAR21586.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR21586.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAR21586.1 - 0.033 14.1 0.2 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF59 PF01883.14 CAR21587.1 - 2.6e-06 27.3 0.0 5.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 CDP-OH_P_transf PF01066.16 CAR21588.1 - 1.7e-17 63.5 0.5 1.7e-17 63.5 0.4 2.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Tom22 PF04281.8 CAR21589.1 - 4e-49 165.6 3.6 4.5e-49 165.5 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Peroxidase_2 PF01328.12 CAR21589.1 - 0.032 12.9 4.0 1.8 7.1 0.0 2.0 1 1 1 2 2 2 0 Peroxidase, family 2 GNAT_acetyltr_2 PF13718.1 CAR21590.1 - 2.2e-80 268.6 0.0 4.2e-80 267.7 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CAR21590.1 - 1.6e-66 223.3 0.0 7.7e-66 221.0 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CAR21590.1 - 2.1e-40 136.3 0.3 7.1e-40 134.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CAR21590.1 - 3.2e-38 129.8 0.7 9.2e-38 128.4 0.5 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain DEAD PF00270.24 CAR21590.1 - 0.0066 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Acetyltransf_7 PF13508.1 CAR21590.1 - 0.013 15.6 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_19 PF13245.1 CAR21590.1 - 0.062 13.0 0.0 0.92 9.3 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NDT80_PhoG PF05224.7 CAR21591.1 - 1.1e-60 204.8 0.0 2.1e-60 203.9 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Nefa_Nip30_N PF10187.4 CAR21592.1 - 0.0032 17.6 12.2 0.0032 17.6 8.4 2.0 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF1108 PF06531.6 CAR21592.1 - 0.091 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) ADH_zinc_N PF00107.21 CAR21593.1 - 2.4e-16 59.4 0.0 4.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR21593.1 - 3.2e-06 26.8 0.3 6.4e-05 22.6 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CAR21593.1 - 0.03 15.2 0.0 0.056 14.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PIR PF00399.14 CAR21594.1 - 6.8e-07 28.4 9.2 6.8e-07 28.4 6.4 2.6 2 0 0 2 2 2 1 Yeast PIR protein repeat CCDC14 PF15254.1 CAR21594.1 - 0.14 10.4 1.5 0.16 10.3 1.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Lipoprotein_2 PF00921.12 CAR21594.1 - 0.21 11.6 4.3 0.24 11.3 3.0 1.0 1 0 0 1 1 1 0 Borrelia lipoprotein FKBP_C PF00254.23 CAR21595.1 - 8.5e-34 115.4 0.0 1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Eaf7 PF07904.8 CAR21596.1 - 1.1e-27 95.8 0.4 1.1e-27 95.8 0.3 1.9 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 DUF3801 PF12687.2 CAR21596.1 - 0.23 11.0 9.9 0.39 10.2 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) S4 PF01479.20 CAR21597.1 - 2.4e-16 58.9 0.0 4.6e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CAR21597.1 - 0.00063 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain LTXXQ PF07813.7 CAR21597.1 - 0.026 14.9 0.9 0.026 14.9 0.6 2.2 2 0 0 2 2 2 0 LTXXQ motif family protein B PF02216.11 CAR21597.1 - 0.044 13.5 0.5 8.2 6.2 0.0 2.6 2 0 0 2 2 2 0 B domain DUF3461 PF11944.3 CAR21597.1 - 0.046 13.5 0.5 0.11 12.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Cas_Cas1 PF01867.11 CAR21597.1 - 0.072 12.1 0.1 0.072 12.1 0.0 1.6 2 0 0 2 2 2 0 CRISPR associated protein Cas1 DUF4359 PF14271.1 CAR21597.1 - 0.13 12.5 0.6 5.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) Urb2 PF10441.4 CAR21597.1 - 0.14 11.7 4.3 0.043 13.4 0.8 1.7 2 0 0 2 2 2 0 Urb2/Npa2 family DUF2229 PF09989.4 CAR21597.1 - 0.58 9.5 3.2 0.54 9.6 0.1 2.0 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) CAP_N PF01213.14 CAR21598.1 - 3.5e-96 322.1 2.6 5.1e-96 321.6 1.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CAR21598.1 - 1.1e-60 203.5 3.5 2.1e-60 202.6 2.4 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CAR21598.1 - 0.0014 18.0 1.8 0.0027 17.1 1.3 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF3060 PF11259.3 CAR21598.1 - 0.23 11.0 2.2 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) SF3b10 PF07189.6 CAR21600.1 - 1.3e-22 79.4 0.6 1.5e-22 79.1 0.4 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Tho2 PF11262.3 CAR21601.1 - 1.7e-43 148.8 6.0 1.7e-43 148.8 4.1 2.9 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CAR21601.1 - 1.6e-22 79.0 0.3 6.3e-22 77.1 0.2 2.2 1 0 0 1 1 1 1 Transcription- and export-related complex subunit C2 PF00168.25 CAR21602.1 - 6.6e-06 25.8 0.0 1.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain RNA_pol_3_Rpc31 PF11705.3 CAR21603.1 - 6.4e-63 212.8 11.9 7.1e-63 212.6 8.2 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PGA2 PF07543.7 CAR21604.1 - 5.4e-16 58.6 10.1 3.1e-13 49.7 7.0 2.0 1 1 0 1 1 1 1 Protein trafficking PGA2 DUF1510 PF07423.6 CAR21604.1 - 0.0051 16.1 2.8 0.0069 15.7 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) IPPT PF01715.12 CAR21604.1 - 0.045 12.7 1.2 0.11 11.5 0.8 1.6 1 1 0 1 1 1 0 IPP transferase DUF2500 PF10694.4 CAR21604.1 - 0.047 13.7 0.2 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF421 PF04239.7 CAR21604.1 - 0.047 13.1 2.0 0.17 11.4 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF421) Mit_KHE1 PF10173.4 CAR21604.1 - 0.13 12.0 1.0 0.16 11.8 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DevR PF01905.11 CAR21604.1 - 0.13 11.0 0.2 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 COX16 PF14138.1 CAR21604.1 - 0.16 12.1 6.6 1.2 9.3 4.6 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 IncA PF04156.9 CAR21604.1 - 2.7 7.5 8.4 5.5 6.5 5.8 1.6 1 1 0 1 1 1 0 IncA protein CAP_GLY PF01302.20 CAR21605.1 - 1.2e-19 69.7 0.1 1.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CAR21605.1 - 4.2e-08 33.3 0.1 1e-07 32.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-like domain ASXH PF13919.1 CAR21605.1 - 0.021 14.5 5.9 0.043 13.6 4.1 1.4 1 1 0 1 1 1 0 Asx homology domain DUF4520 PF15016.1 CAR21605.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4520) LSM PF01423.17 CAR21606.1 - 2.1e-17 62.4 0.3 2.7e-17 62.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain UPRTase PF14681.1 CAR21607.1 - 1.2e-77 259.8 0.0 1.5e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CAR21607.1 - 0.0023 17.6 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CoA_binding_2 PF13380.1 CAR21607.1 - 0.0038 17.3 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Flu_C_NS1 PF03506.8 CAR21607.1 - 0.065 12.9 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.14 CAR21608.1 - 2.1e-121 405.0 0.0 2.4e-121 404.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR21608.1 - 7.9e-05 21.4 0.0 0.0041 15.7 0.0 2.0 2 0 0 2 2 2 2 MreB/Mbl protein DUF2009 PF09418.5 CAR21609.1 - 9.2e-225 746.6 0.3 1.1e-224 746.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CAR21609.1 - 1.8e-05 24.5 7.5 3.1e-05 23.7 5.2 1.4 1 0 0 1 1 1 1 B-box zinc finger YqbF PF14553.1 CAR21610.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Arginase PF00491.16 CAR21611.1 - 2.2e-85 286.3 0.0 2.6e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 CAR21611.1 - 0.015 15.4 0.1 0.034 14.3 0.1 1.7 2 0 0 2 2 2 0 UPF0489 domain Pga1 PF10333.4 CAR21613.1 - 7.5e-33 113.6 0.0 8.8e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Peptidase_M14 PF00246.19 CAR21614.1 - 5.3e-70 236.1 0.0 6.6e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CAR21614.1 - 0.053 12.3 0.0 0.57 9.0 0.0 2.1 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Endosulfine PF04667.12 CAR21615.1 - 4.4e-31 106.6 0.2 5.9e-31 106.2 0.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.7 CAR21616.1 - 6.9e-11 41.8 2.5 9.6e-11 41.3 1.7 1.4 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF202 PF02656.10 CAR21616.1 - 8.8 6.6 7.2 8.3 6.7 2.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) WLM PF08325.5 CAR21617.1 - 7.8e-49 166.0 0.1 1.3e-48 165.3 0.0 1.3 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 CAR21617.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF45 zf-AN1 PF01428.11 CAR21618.1 - 5.6e-12 45.3 12.2 1e-11 44.4 8.4 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger FYVE PF01363.16 CAR21618.1 - 0.0092 15.8 2.7 0.019 14.8 1.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger Integrin_beta PF00362.13 CAR21618.1 - 0.051 12.4 1.2 0.067 12.0 0.8 1.1 1 0 0 1 1 1 0 Integrin, beta chain Epimerase PF01370.16 CAR21619.1 - 1e-15 57.8 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR21619.1 - 9.8e-14 50.7 0.0 1.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAR21619.1 - 6.1e-10 38.4 0.0 8.5e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CAR21619.1 - 2.1e-09 37.6 0.0 1.3e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CAR21619.1 - 1.1e-07 31.6 0.0 2.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CAR21619.1 - 5.6e-07 29.6 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CAR21619.1 - 0.078 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.20 CAR21620.1 - 1.9e-32 112.4 3.2 5.2e-32 111.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21620.1 - 6.8e-13 48.2 0.7 3e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CAR21620.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Med15 PF09606.5 CAR21620.1 - 5.1 5.1 82.9 7.2 4.6 57.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal A_deaminase PF00962.17 CAR21621.1 - 1.5e-76 257.4 0.0 1.7e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 CAR21621.1 - 0.017 15.1 0.0 0.049 13.6 0.0 1.8 2 1 1 3 3 3 0 Amidohydrolase Cas_Csa5 PF09702.5 CAR21622.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) Aminotran_1_2 PF00155.16 CAR21623.1 - 2e-15 56.6 0.0 2.7e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CAR21623.1 - 0.038 12.5 0.0 0.062 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Prefoldin_2 PF01920.15 CAR21624.1 - 3.7e-23 81.3 9.9 4.4e-23 81.0 6.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit SMK-1 PF04802.10 CAR21624.1 - 0.00081 18.9 1.8 0.001 18.6 1.3 1.2 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Nop16 PF09420.5 CAR21624.1 - 0.0014 18.7 1.4 0.0018 18.3 1.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 SPX PF03105.14 CAR21624.1 - 0.04 13.7 0.1 0.064 13.0 0.1 1.3 1 1 0 1 1 1 0 SPX domain Nup54 PF13874.1 CAR21624.1 - 0.085 12.5 0.8 0.085 12.5 0.5 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DNApol3-delta_C PF09115.5 CAR21624.1 - 0.19 11.7 1.1 0.49 10.4 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal HemX PF04375.9 CAR21624.1 - 0.19 10.2 2.4 0.22 10.0 1.6 1.3 1 1 0 1 1 1 0 HemX Laminin_II PF06009.7 CAR21624.1 - 0.26 11.0 2.4 0.34 10.6 1.5 1.5 1 1 0 1 1 1 0 Laminin Domain II DUF2570 PF10828.3 CAR21624.1 - 0.32 10.6 4.8 0.22 11.1 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2570) Med4 PF10018.4 CAR21624.1 - 0.41 10.0 3.6 0.23 10.8 1.3 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Seryl_tRNA_N PF02403.17 CAR21624.1 - 0.48 10.4 10.2 4.1 7.4 0.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4611 PF15387.1 CAR21624.1 - 0.68 10.1 4.7 1.2 9.2 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) BLOC1_2 PF10046.4 CAR21624.1 - 0.74 9.9 6.9 0.85 9.7 0.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 CAR21624.1 - 0.89 9.1 9.1 1.2 8.7 6.3 1.2 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 CAR21624.1 - 5.9 7.1 9.9 8.5 6.6 6.9 1.2 1 0 0 1 1 1 0 AAA domain Trep_dent_lipo PF09710.5 CAR21625.1 - 0.016 13.9 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Ammonium_transp PF00909.16 CAR21626.1 - 7.2e-127 423.1 27.0 8.3e-127 422.9 18.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Far-17a_AIG1 PF04750.9 CAR21627.1 - 3.5e-18 65.5 1.7 4.4e-18 65.1 1.2 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Asparaginase PF00710.15 CAR21628.1 - 1.3e-12 47.2 1.1 4.9e-11 42.0 0.7 2.4 1 1 0 1 1 1 1 Asparaginase Epimerase PF01370.16 CAR21629.1 - 1.5e-16 60.5 0.0 2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR21629.1 - 3e-12 45.8 0.0 4.4e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAR21629.1 - 4.8e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CAR21629.1 - 2.6e-05 23.9 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CAR21629.1 - 4.9e-05 23.3 0.3 0.00015 21.7 0.0 1.9 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CAR21629.1 - 9.2e-05 21.4 0.0 0.0002 20.3 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CAR21629.1 - 0.00033 19.6 0.2 0.00051 19.0 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 CAR21629.1 - 0.00078 19.7 0.1 0.0059 16.8 0.0 2.3 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 CAR21629.1 - 0.015 14.5 0.1 0.025 13.8 0.1 1.6 1 1 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 CAR21629.1 - 0.027 13.3 0.2 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain DUF650 PF04894.7 CAR21629.1 - 0.048 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF650) adh_short_C2 PF13561.1 CAR21629.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.20 CAR21630.1 - 9.4e-60 201.9 1.0 5e-40 137.2 0.1 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21630.1 - 1.5e-26 93.0 0.3 3.6e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR21630.1 - 0.0018 17.3 0.1 0.0057 15.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR21630.1 - 0.0048 15.9 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 CAR21630.1 - 0.0062 17.0 0.1 0.0062 17.0 0.1 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 CAR21630.1 - 0.018 13.9 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CAR21630.1 - 0.033 13.9 0.1 0.85 9.2 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CAR21630.1 - 0.071 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_L44 PF00935.14 CAR21631.1 - 2.9e-33 113.7 10.6 4.5e-33 113.0 7.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Chs3p PF12271.3 CAR21632.1 - 4.7e-100 334.3 18.9 1.1e-99 333.1 13.1 1.5 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit ASC PF00858.19 CAR21633.1 - 0.029 13.0 0.7 0.03 13.0 0.5 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel zf-ribbon_3 PF13248.1 CAR21633.1 - 0.039 13.1 0.9 0.14 11.4 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CAR21633.1 - 0.088 12.4 1.9 0.11 12.1 1.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 CAR21633.1 - 0.57 9.9 4.1 2.5 7.8 2.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 DNA_ligase_ZBD PF03119.11 CAR21633.1 - 6.3 6.6 7.7 97 2.7 5.3 2.3 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-tcix PF14952.1 CAR21633.1 - 7.3 6.0 8.1 9.2 5.6 0.8 2.5 2 1 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding GTP_EFTU PF00009.22 CAR21634.1 - 1.9e-53 180.6 0.0 3.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CAR21634.1 - 1.4e-14 53.7 0.0 5.5e-14 51.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR21634.1 - 2.7e-10 40.1 0.0 7e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CAR21634.1 - 2.1e-08 33.9 0.0 6e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CAR21634.1 - 0.00062 19.3 0.0 0.0016 17.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 CAR21634.1 - 0.007 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NatB_MDM20 PF09797.4 CAR21635.1 - 0.063 11.9 0.1 0.087 11.5 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TFIIA PF03153.8 CAR21636.1 - 1.6 8.5 9.0 2.1 8.1 6.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nup54 PF13874.1 CAR21638.1 - 0.32 10.6 4.7 0.13 11.8 0.4 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DNA_RNApol_7kD PF03604.8 CAR21639.1 - 1.9e-16 59.1 1.8 2.5e-16 58.8 1.3 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 CAR21639.1 - 0.0031 17.2 0.4 0.0043 16.8 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 CAR21639.1 - 0.005 16.5 0.2 0.0051 16.4 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 CAR21639.1 - 0.0057 16.2 0.7 2.9 7.6 0.1 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Prok-RING_1 PF14446.1 CAR21639.1 - 0.007 16.0 0.7 0.0092 15.6 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 FYDLN_acid PF09538.5 CAR21639.1 - 0.027 15.0 0.4 0.032 14.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NCD3G PF07562.9 CAR21639.1 - 0.034 13.8 0.2 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR C1_1 PF00130.17 CAR21639.1 - 0.039 13.6 0.3 0.055 13.2 0.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF951 PF06107.6 CAR21639.1 - 0.063 12.8 1.5 1.5 8.3 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) A2L_zn_ribbon PF08792.5 CAR21639.1 - 0.063 12.7 0.9 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF4428 PF14471.1 CAR21639.1 - 0.065 12.9 1.5 1.3 8.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) FYVE_2 PF02318.11 CAR21639.1 - 0.072 12.9 0.2 0.077 12.8 0.2 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2197 PF09963.4 CAR21639.1 - 0.093 12.7 2.4 7.2 6.6 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF2318 PF10080.4 CAR21639.1 - 0.1 12.3 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Gin PF10764.4 CAR21639.1 - 0.12 12.0 0.2 1.4 8.7 0.0 2.2 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin Ribosomal_L40e PF01020.12 CAR21639.1 - 0.19 11.3 2.4 0.25 10.9 1.7 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Zn_ribbon_recom PF13408.1 CAR21639.1 - 0.21 11.8 3.2 3.4 8.0 0.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.5 CAR21639.1 - 0.37 10.7 3.4 1.2 9.2 2.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CAR21639.1 - 0.44 10.4 3.3 1.9 8.3 2.6 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 CAR21639.1 - 0.6 9.4 2.6 8.2 5.8 2.1 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding Ribosomal_L44 PF00935.14 CAR21639.1 - 2.2 8.3 4.7 11 6.1 0.4 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 DUP PF00674.13 CAR21640.1 - 1.3e-10 41.2 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 DUP family DUP PF00674.13 CAR21641.1 - 1.2e-26 92.7 0.0 7.1e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 DUP family bZIP_1 PF00170.16 CAR21642.1 - 2.4e-07 30.5 3.7 6e-07 29.3 2.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 CAR21642.1 - 1.2e-06 28.9 4.8 1.2e-06 28.9 3.3 6.1 3 3 1 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 CAR21642.1 - 3.8e-05 23.4 5.4 3.8e-05 23.4 3.8 2.6 2 0 0 2 2 2 1 Basic region leucine zipper Mem_trans PF03547.13 CAR21642.1 - 2.9 6.0 5.4 5.2 5.2 3.7 1.5 1 0 0 1 1 1 0 Membrane transport protein PAT1 PF09770.4 CAR21642.1 - 8.9 4.4 86.2 0.19 9.9 32.0 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CAR21642.1 - 9.5 3.7 44.2 2.1 5.9 20.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) FAA_hydrolase PF01557.13 CAR21643.1 - 1.5e-45 155.3 0.0 2.2e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family dCMP_cyt_deam_1 PF00383.17 CAR21644.1 - 3.2e-25 87.7 2.6 4.9e-25 87.1 1.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 CAR21644.1 - 0.046 13.4 0.5 0.075 12.7 0.3 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Packaging_FI PF14000.1 CAR21644.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA packaging protein FI PS_Dcarbxylase PF02666.10 CAR21645.1 - 7.5e-75 250.6 0.0 1.5e-74 249.7 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Apc1 PF12859.2 CAR21646.1 - 8.1e-16 58.1 0.1 8.1e-16 58.1 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 RRM_1 PF00076.17 CAR21648.1 - 8.3e-26 89.4 0.4 7.3e-18 63.9 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21648.1 - 5.1e-18 64.8 0.3 2.5e-11 43.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR21648.1 - 3e-07 30.1 0.9 3.6e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR21648.1 - 0.0069 16.1 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF4410 PF14366.1 CAR21648.1 - 5.9 6.6 8.1 0.41 10.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) Mid2 PF04478.7 CAR21649.1 - 8.3e-05 22.0 0.0 8.3e-05 22.0 0.0 3.3 3 1 0 3 3 3 1 Mid2 like cell wall stress sensor Glyco_hydro_8 PF01270.12 CAR21649.1 - 0.013 14.2 0.4 0.023 13.4 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 DUF912 PF06024.7 CAR21649.1 - 0.063 13.3 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Adeno_E3_CR2 PF02439.10 CAR21649.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ribosomal_L22 PF00237.14 CAR21650.1 - 1.4e-19 69.9 0.0 2.8e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SHR3_chaperone PF08229.6 CAR21651.1 - 5e-78 260.5 1.3 5.5e-78 260.4 0.9 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Protocadherin PF08374.6 CAR21651.1 - 0.047 13.3 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Protocadherin DUF1072 PF06380.6 CAR21651.1 - 0.059 13.0 0.1 7.9 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) COX14 PF14880.1 CAR21651.1 - 0.16 11.5 3.4 0.3 10.7 0.6 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4131 PF13567.1 CAR21651.1 - 0.17 11.2 1.9 1.3 8.4 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspannin PF00335.15 CAR21651.1 - 0.68 9.1 6.4 6.5 5.9 4.4 2.2 1 1 0 1 1 1 0 Tetraspanin family Ribosomal_S3_C PF00189.15 CAR21652.1 - 1.2e-15 57.4 0.1 2.4e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CAR21652.1 - 3.3e-12 45.7 0.1 1.2e-11 44.0 0.1 1.9 2 0 0 2 2 2 1 KH domain Ras PF00071.17 CAR21653.1 - 1.4e-46 157.8 0.0 1.9e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR21653.1 - 3.1e-15 56.7 0.0 1.7e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR21653.1 - 1.6e-06 27.5 0.0 2.5e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR21653.1 - 0.00089 18.7 0.0 0.0059 16.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR21653.1 - 0.0095 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAR21653.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase adh_short PF00106.20 CAR21654.1 - 3e-09 37.0 0.0 9.2e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR21654.1 - 5.4e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CAR21654.1 - 0.00032 20.5 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1768 PF08719.6 CAR21654.1 - 0.0081 15.9 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) WD40 PF00400.27 CAR21655.1 - 1.7e-07 30.8 0.0 0.13 12.2 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Aerolysin PF01117.15 CAR21655.1 - 0.092 11.6 0.1 0.33 9.8 0.0 1.8 2 0 0 2 2 2 0 Aerolysin toxin HALZ PF02183.13 CAR21655.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF1777 PF08648.7 CAR21656.1 - 3.8e-11 43.0 1.0 4.3e-11 42.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) RRM_1 PF00076.17 CAR21657.1 - 3.4e-07 29.8 0.0 7.7e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21657.1 - 5.8e-07 29.4 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CAR21658.1 - 2.8e-65 220.0 0.0 5.2e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21658.1 - 5.1e-24 84.7 0.0 8.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR21658.1 - 0.014 14.4 0.1 0.13 11.1 0.0 2.1 1 1 0 2 2 2 0 Kinase-like APH PF01636.18 CAR21658.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 CAR21659.1 - 6.8e-27 92.7 0.4 1.2e-26 91.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CAR21659.1 - 1.4e-22 79.6 0.4 2.9e-22 78.5 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain MIF PF01187.13 CAR21659.1 - 0.067 13.2 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) UCH PF00443.24 CAR21660.1 - 3.1e-56 190.4 2.2 4.9e-56 189.8 1.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR21660.1 - 5.4e-18 65.4 1.1 8.3e-18 64.8 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-AD PF07776.10 CAR21660.1 - 0.067 13.1 0.5 0.35 10.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Prenyltrans PF00432.16 CAR21660.1 - 0.09 12.3 0.9 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat ELFV_dehydrog PF00208.16 CAR21661.1 - 6.4e-59 199.4 0.0 1.7e-58 198.1 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CAR21661.1 - 6.9e-20 70.1 0.0 4.2e-10 37.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase DUF4363 PF14276.1 CAR21661.1 - 0.0019 17.9 1.3 0.0051 16.4 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4363) ELFV_dehydrog_N PF02812.13 CAR21661.1 - 0.0048 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain JAB PF01398.16 CAR21662.1 - 9.1e-28 96.2 0.1 2e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CAR21662.1 - 6.5e-07 28.8 0.0 1.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CAR21662.1 - 5.9e-05 22.6 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) PAS_5 PF07310.8 CAR21663.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 PAS domain PQQ_2 PF13360.1 CAR21663.1 - 0.064 12.7 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.27 CAR21663.1 - 0.64 9.9 6.5 75 3.4 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Tim17 PF02466.14 CAR21664.1 - 3.3e-49 166.1 2.1 4.2e-49 165.8 1.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 CAR21664.1 - 0.013 14.7 0.8 0.049 12.9 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Gly-zipper_Omp PF13488.1 CAR21664.1 - 0.56 9.8 4.5 0.88 9.2 0.1 2.2 2 0 0 2 2 2 0 Glycine zipper PI3K_1B_p101 PF10486.4 CAR21665.1 - 0.054 11.0 0.8 0.098 10.2 0.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Arm PF00514.18 CAR21666.1 - 1.5e-82 268.9 19.0 1.3e-12 47.0 0.0 9.0 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 CAR21666.1 - 1.5e-26 92.3 6.1 3.7e-26 91.1 4.2 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 CAR21666.1 - 1.2e-20 73.5 0.2 2e-06 28.0 0.1 5.6 1 1 6 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 CAR21666.1 - 1.7e-18 66.4 1.8 4.5e-05 23.8 0.0 6.0 3 2 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 CAR21666.1 - 5e-12 44.8 0.2 0.037 14.0 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.8 CAR21666.1 - 3.7e-07 29.5 1.4 0.23 10.5 0.0 4.7 3 2 2 5 5 5 3 Armadillo-like V-ATPase_H_C PF11698.3 CAR21666.1 - 3.2e-05 23.8 0.2 0.24 11.3 0.0 4.5 2 1 3 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 CAR21666.1 - 9.8e-05 20.8 2.4 0.0052 15.1 0.5 2.8 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 CAR21666.1 - 0.00022 19.7 1.2 0.0085 14.4 0.4 2.7 1 1 0 2 2 2 1 Adaptin N terminal region FAST_1 PF06743.10 CAR21666.1 - 0.054 13.2 0.3 3 7.6 0.0 3.2 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 PIH1 PF08190.7 CAR21666.1 - 0.069 12.5 2.0 0.11 11.9 1.4 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Gmad2 PF10648.4 CAR21667.1 - 0.087 13.0 8.8 3.4 7.9 0.3 3.9 1 1 4 5 5 5 0 Immunoglobulin-like domain of bacterial spore germination SspP PF08179.7 CAR21667.1 - 0.38 10.9 22.8 24 5.2 0.2 5.3 5 0 0 5 5 5 0 Small acid-soluble spore protein P family MARVEL PF01284.18 CAR21668.1 - 6.8e-26 90.8 7.0 8.8e-26 90.4 4.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain CD52 PF15116.1 CAR21668.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.8 3 0 0 3 3 3 0 CAMPATH-1 antigen Amastin PF07344.6 CAR21668.1 - 2.4 7.7 6.1 0.94 9.0 1.6 1.9 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF998 PF06197.8 CAR21668.1 - 3.1 7.0 12.2 1 8.6 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF998) RDD PF06271.7 CAR21668.1 - 3.3 7.6 7.6 8.8 6.2 5.3 1.8 1 1 0 1 1 1 0 RDD family GATase_4 PF13230.1 CAR21669.1 - 5.5e-19 67.9 0.1 5.7e-18 64.5 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 CAR21669.1 - 5.1e-11 42.6 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CAR21669.1 - 1.2e-08 34.0 0.0 7.3e-08 31.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 CAR21669.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Tyr_Deacylase PF02580.11 CAR21670.1 - 4.8e-48 162.8 0.2 5.4e-48 162.6 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Chitin_synth_1 PF01644.12 CAR21671.1 - 6.5e-73 243.9 0.1 1e-72 243.2 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CAR21671.1 - 2.5e-28 97.5 0.1 5.9e-28 96.3 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CAR21671.1 - 1.5e-17 63.2 4.9 1.6e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CAR21671.1 - 2.5e-12 46.9 4.2 1.6e-11 44.2 2.9 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CAR21671.1 - 5.4e-10 39.4 0.0 3.7e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CAR21671.1 - 0.012 15.3 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CAR21671.1 - 0.043 13.1 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 SUR7 PF06687.7 CAR21674.1 - 1.6e-40 138.9 8.7 2.1e-40 138.5 6.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CAR21674.1 - 0.097 12.3 20.4 0.031 13.9 10.1 2.2 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 CAR21674.1 - 0.21 11.4 17.0 0.02 14.7 8.6 1.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4491 PF14898.1 CAR21674.1 - 1.9 8.7 10.1 0.15 12.1 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) DUF21 PF01595.15 CAR21674.1 - 2.4 7.4 0.0 2.4 7.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF21 RRM_1 PF00076.17 CAR21677.1 - 2.3e-16 59.1 0.0 3.8e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21677.1 - 4.8e-09 36.0 0.0 6.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 CAR21677.1 - 0.052 13.2 27.0 0.015 15.0 9.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) GAGA_bind PF06217.7 CAR21677.1 - 2.5 7.9 16.6 3.8 7.3 6.6 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family SAGA-Tad1 PF12767.2 CAR21677.1 - 8.1 6.0 24.2 2.9 7.4 9.7 2.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Septin PF00735.13 CAR21678.1 - 1.8e-74 250.3 1.6 1.4e-66 224.4 0.2 2.5 3 0 0 3 3 3 2 Septin AAA_22 PF13401.1 CAR21678.1 - 0.0021 18.1 0.0 0.013 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CAR21678.1 - 0.0051 16.4 0.1 0.017 14.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR21678.1 - 0.0064 16.3 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CAR21678.1 - 0.0076 16.0 2.3 0.022 14.5 0.0 2.8 3 1 0 3 3 3 1 Dynamin family AIG1 PF04548.11 CAR21678.1 - 0.0083 15.2 2.0 0.33 10.0 0.0 3.1 4 0 0 4 4 4 1 AIG1 family AAA_16 PF13191.1 CAR21678.1 - 0.019 14.9 1.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CAR21678.1 - 0.022 14.2 0.7 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 CAR21678.1 - 0.035 13.5 0.5 0.099 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 CAR21678.1 - 0.042 13.5 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CAR21678.1 - 0.049 13.9 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 CAR21678.1 - 0.054 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein DUF258 PF03193.11 CAR21678.1 - 0.074 12.2 0.0 0.22 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CAR21678.1 - 0.13 12.0 0.3 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CAR21678.1 - 0.15 12.2 1.2 0.51 10.5 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) OmpH PF03938.9 CAR21678.1 - 2.6 7.9 12.9 6 6.7 9.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Angiomotin_C PF12240.3 CAR21679.1 - 0.055 12.9 1.9 0.099 12.1 0.2 2.0 2 0 0 2 2 2 0 Angiomotin C terminal FadA PF09403.5 CAR21679.1 - 0.22 11.5 2.6 11 6.0 0.1 2.8 2 1 1 3 3 3 0 Adhesion protein FadA YjeF_N PF03853.10 CAR21680.1 - 5.3e-35 120.5 0.0 6.4e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus T2SE_Nter PF05157.10 CAR21680.1 - 0.14 12.2 0.0 11 6.0 0.0 2.8 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein E, N-terminal domain SMK-1 PF04802.10 CAR21681.1 - 1.5e-63 213.8 4.0 1.5e-63 213.8 2.8 3.1 4 1 0 4 4 4 1 Component of IIS longevity pathway SMK-1 adh_short_C2 PF13561.1 CAR21682.1 - 9.8e-25 87.7 0.0 1.2e-24 87.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR21682.1 - 2.4e-18 66.5 1.7 2.4e-18 66.5 1.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CAR21682.1 - 1.9e-07 30.9 1.1 3.1e-07 30.2 0.3 1.6 2 0 0 2 2 2 1 KR domain ArfGap PF01412.13 CAR21683.1 - 1.3e-33 115.2 0.0 3.7e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3482 PF11981.3 CAR21683.1 - 0.00023 20.5 0.2 0.00052 19.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3482) Colicin-DNase PF12639.2 CAR21683.1 - 0.019 15.2 1.0 6 7.1 0.0 2.8 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Rtt106 PF08512.7 CAR21684.1 - 8.2e-27 93.0 0.4 2e-26 91.8 0.3 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Spore_SspJ PF09575.5 CAR21684.1 - 0.098 12.8 1.8 0.23 11.6 1.3 1.6 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) RIO1 PF01163.17 CAR21685.1 - 4.6e-41 140.2 0.1 9.5e-41 139.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CAR21685.1 - 8.2e-32 109.1 0.1 1.7e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CAR21685.1 - 6.4e-09 35.8 0.1 0.00066 19.4 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CAR21685.1 - 0.0028 16.7 0.0 0.067 12.2 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.15 CAR21686.1 - 4.1e-238 791.2 9.8 4.6e-238 791.0 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR21686.1 - 5.1e-17 61.4 0.7 9e-16 57.3 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CAR21686.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2603 PF10788.4 CAR21686.1 - 0.052 13.3 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) KH_1 PF00013.24 CAR21687.1 - 1.5e-06 27.7 0.0 2.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CAR21687.1 - 6.2e-05 22.5 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CAR21687.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.6 2 0 0 2 2 2 0 KH domain Y_phosphatase PF00102.22 CAR21688.1 - 5.7e-56 189.4 0.5 1.4e-55 188.2 0.3 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CAR21688.1 - 0.00019 21.7 0.0 0.00043 20.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CAR21688.1 - 0.0031 17.0 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CAR21688.1 - 0.0034 17.4 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF2422 PF10337.4 CAR21689.1 - 3.7e-08 32.6 24.4 5.2e-08 32.1 4.7 4.0 3 1 1 4 4 4 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CAR21689.1 - 1.1e-06 28.5 27.1 1.2e-05 25.2 5.2 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2421 PF10334.4 CAR21689.1 - 0.013 15.0 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DUF2697 PF10906.3 CAR21690.1 - 7.2e-29 99.6 0.6 8.7e-29 99.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) VID27 PF08553.5 CAR21691.1 - 5.1e-293 974.2 18.8 6.2e-293 973.9 13.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Neugrin PF06413.6 CAR21692.1 - 2.5e-14 53.6 3.7 2.5e-14 53.6 2.6 1.4 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 CAR21692.1 - 0.0017 18.3 4.9 0.0028 17.6 3.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.7 CAR21692.1 - 0.0074 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain DUF2267 PF10025.4 CAR21692.1 - 0.03 14.3 0.2 0.054 13.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Sigma70_r4 PF04545.11 CAR21692.1 - 0.11 11.8 0.3 0.21 10.9 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Put_DNA-bind_N PF06971.8 CAR21692.1 - 0.2 11.4 1.9 0.25 11.1 0.0 2.1 2 1 1 3 3 3 0 Putative DNA-binding protein N-terminus UPF0118 PF01594.11 CAR21693.1 - 0.087 11.7 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 LIM_bind PF01803.11 CAR21694.1 - 1.8e-62 210.6 0.0 1.8e-62 210.6 0.0 1.6 2 0 0 2 2 2 1 LIM-domain binding protein PAPA-1 PF04795.7 CAR21695.1 - 9.7e-15 55.0 9.9 9.7e-15 55.0 6.8 2.5 2 1 0 2 2 2 1 PAPA-1-like conserved region Hex_IIIa PF02455.11 CAR21695.1 - 0.45 9.1 13.9 0.53 8.9 9.7 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF3246 PF11596.3 CAR21695.1 - 0.84 8.8 5.3 1.1 8.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Jnk-SapK_ap_N PF09744.4 CAR21695.1 - 1.8 8.5 9.6 5.2 7.0 6.0 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 IncA PF04156.9 CAR21695.1 - 1.8 8.1 6.5 2.1 7.9 4.5 1.2 1 0 0 1 1 1 0 IncA protein Lipl32 PF12103.3 CAR21695.1 - 1.9 7.8 5.1 0.69 9.3 1.6 1.7 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order RabGAP-TBC PF00566.13 CAR21696.1 - 2.5e-31 108.8 20.5 1.4e-28 99.8 14.2 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Rap1-DNA-bind PF09197.5 CAR21697.1 - 2.2e-43 147.0 4.7 1.3e-39 134.9 0.1 2.8 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.3 CAR21697.1 - 1.4e-23 82.5 0.0 8.4e-23 80.0 0.0 2.4 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 CAR21697.1 - 5.1e-09 36.0 0.9 8.1e-08 32.2 0.0 3.2 5 0 0 5 5 5 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 CAR21697.1 - 3.8e-08 33.0 0.3 8.5e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 Rap1 Myb domain BRCT PF00533.21 CAR21697.1 - 6.3e-05 23.0 0.1 0.00039 20.5 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_6 PF13921.1 CAR21697.1 - 0.0098 15.9 0.2 0.45 10.6 0.0 2.9 2 1 0 2 2 2 1 Myb-like DNA-binding domain Metallophos PF00149.23 CAR21698.1 - 2.5e-09 36.8 0.2 6.1e-09 35.5 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Hpt PF01627.18 CAR21699.1 - 1.6e-12 47.2 0.9 2e-12 46.9 0.6 1.2 1 0 0 1 1 1 1 Hpt domain DUF1804 PF08822.6 CAR21699.1 - 0.041 13.6 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) MgsA_C PF12002.3 CAR21700.1 - 9.9e-53 178.2 0.4 2e-52 177.2 0.3 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CAR21700.1 - 1e-15 58.1 0.0 2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR21700.1 - 4.7e-13 48.7 0.1 1.4e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAR21700.1 - 3.9e-08 33.4 0.1 6.5e-06 26.2 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CAR21700.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAR21700.1 - 1.8e-07 30.9 0.0 4.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAR21700.1 - 5.9e-06 26.4 0.3 9.4e-05 22.5 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAR21700.1 - 0.00015 21.7 0.0 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CAR21700.1 - 0.00025 20.2 0.1 0.049 12.7 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.1 CAR21700.1 - 0.00041 20.0 0.0 0.039 13.6 0.0 3.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Sigma54_activat PF00158.21 CAR21700.1 - 0.00053 19.5 0.0 0.019 14.4 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CAR21700.1 - 0.0017 17.8 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CAR21700.1 - 0.0017 19.1 0.1 0.016 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sgf11 PF08209.6 CAR21700.1 - 0.0025 17.0 0.0 0.0049 16.1 0.0 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) AAA_18 PF13238.1 CAR21700.1 - 0.0028 17.9 0.1 0.0093 16.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 CAR21700.1 - 0.0029 16.5 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 CAR21700.1 - 0.0045 16.6 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAR21700.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 CAR21700.1 - 0.0067 16.0 0.5 0.025 14.1 0.1 2.1 2 1 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 CAR21700.1 - 0.0084 16.0 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_3 PF07726.6 CAR21700.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CAR21700.1 - 0.011 15.5 0.6 0.14 11.9 0.1 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 CAR21700.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 CAR21700.1 - 0.02 15.2 0.1 0.046 14.0 0.1 1.9 1 1 0 1 1 1 0 ABC transporter TIP49 PF06068.8 CAR21700.1 - 0.024 13.3 0.1 0.064 11.9 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 CAR21700.1 - 0.074 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 CAR21700.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CAR21700.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 CAR21700.1 - 0.13 11.8 0.1 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 CAR21700.1 - 0.16 11.3 1.2 1.4 8.2 0.0 2.5 2 1 0 3 3 3 0 AAA-like domain Hydrolase_6 PF13344.1 CAR21701.1 - 3.7e-29 100.5 0.1 1.4e-28 98.7 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR21701.1 - 2.4e-12 46.3 0.0 4.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CAR21701.1 - 4.4e-11 43.5 0.0 1.2e-10 42.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR21701.1 - 2.8e-06 27.6 0.0 0.0028 17.8 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 CAR21701.1 - 0.0083 15.5 0.3 0.042 13.2 0.0 1.9 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) SRP54 PF00448.17 CAR21701.1 - 0.031 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Glyco_transf_22 PF03901.12 CAR21702.1 - 3.2e-84 283.3 29.7 3.8e-84 283.1 20.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Adenylsucc_synt PF00709.16 CAR21703.1 - 1.1e-166 554.6 0.0 1.3e-166 554.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MCD PF05292.6 CAR21703.1 - 0.12 11.0 0.0 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) AA_permease_2 PF13520.1 CAR21704.1 - 2.2e-67 227.4 53.7 2.8e-67 227.1 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR21704.1 - 6.1e-17 61.1 46.6 8.3e-17 60.6 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease POP1 PF06978.6 CAR21705.1 - 3.8e-66 222.3 16.2 3.8e-66 222.3 11.2 2.5 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CAR21705.1 - 6.3e-34 115.6 0.4 5.6e-33 112.6 0.5 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.16 CAR21705.1 - 0.00069 19.0 0.0 0.011 15.1 0.0 2.5 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain Amidohydro_1 PF01979.15 CAR21707.1 - 1e-48 166.7 0.0 1.2e-48 166.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CAR21707.1 - 2.3e-05 24.0 0.0 6.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CAR21707.1 - 0.00018 20.8 0.3 0.45 9.6 0.0 3.0 2 2 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CAR21707.1 - 0.00042 20.4 0.1 0.37 10.7 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase A_deaminase PF00962.17 CAR21707.1 - 0.022 13.7 0.1 0.091 11.6 0.0 1.9 2 0 0 2 2 2 0 Adenosine/AMP deaminase Ssu72 PF04722.8 CAR21708.1 - 1.9e-86 288.3 0.0 2.2e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Peptidase_C54 PF03416.14 CAR21709.1 - 2.2e-73 246.8 0.0 6.6e-73 245.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C54 G-patch PF01585.18 CAR21710.1 - 1.2e-14 53.8 0.7 3.6e-14 52.2 0.5 1.9 1 0 0 1 1 1 1 G-patch domain UPF0258 PF06789.7 CAR21710.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) G-patch_2 PF12656.2 CAR21710.1 - 1.3 8.9 5.8 0.24 11.2 0.1 2.6 2 0 0 2 2 2 0 DExH-box splicing factor binding site SID PF11778.3 CAR21711.1 - 2.8e-50 169.8 2.8 1.7e-49 167.3 1.9 2.5 1 0 0 1 1 1 1 Septation initiation TPR_MLP1_2 PF07926.7 CAR21711.1 - 0.00028 20.6 22.7 0.00028 20.6 15.7 7.8 3 2 1 6 6 6 4 TPR/MLP1/MLP2-like protein IncA PF04156.9 CAR21711.1 - 0.0028 17.3 13.7 0.0028 17.3 9.5 6.6 1 1 4 6 6 6 2 IncA protein DUF1229 PF06797.6 CAR21711.1 - 0.097 11.4 1.2 0.15 10.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Reo_sigmaC PF04582.7 CAR21711.1 - 0.2 10.8 44.4 0.077 12.1 2.3 5.6 1 1 1 5 5 5 0 Reovirus sigma C capsid protein DnaJ PF00226.26 CAR21712.1 - 2.4e-26 91.2 0.3 9.6e-26 89.3 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 CAR21712.1 - 1.4e-08 34.6 2.3 1.4e-08 34.6 1.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CAR21712.1 - 5.7e-08 32.8 5.8 0.001 19.1 1.1 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CAR21712.1 - 2.7e-07 30.5 9.9 0.0013 18.9 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 CAR21712.1 - 6.3e-06 26.2 1.9 6.3e-06 26.2 1.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CAR21712.1 - 9.9e-05 22.4 6.7 0.071 13.4 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CAR21712.1 - 0.00027 20.7 6.4 0.15 11.9 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger AKAP95 PF04988.7 CAR21712.1 - 0.0093 15.7 0.3 0.0093 15.7 0.2 2.9 3 0 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) zf-H2C2_2 PF13465.1 CAR21712.1 - 0.13 12.5 4.4 4.6 7.7 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain GST_C PF00043.20 CAR21713.1 - 6.9e-21 74.0 0.0 2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CAR21713.1 - 6.4e-14 51.8 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CAR21713.1 - 9.4e-10 38.3 0.0 2.5e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CAR21713.1 - 4.9e-09 36.2 0.0 1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAR21713.1 - 0.032 14.1 0.0 0.032 14.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3682 PF12446.3 CAR21713.1 - 0.086 13.1 9.7 0.14 12.4 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) AUX_IAA PF02309.11 CAR21713.1 - 0.11 12.2 1.1 0.16 11.7 0.8 1.3 1 0 0 1 1 1 0 AUX/IAA family LMBR1 PF04791.11 CAR21713.1 - 0.11 11.0 0.2 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Activator_LAG-3 PF11498.3 CAR21713.1 - 5.5 5.6 25.2 7.9 5.1 17.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Elongin_A PF06881.6 CAR21714.1 - 2.8e-16 59.8 10.3 1e-13 51.6 0.5 2.5 1 1 1 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A PAT1 PF09770.4 CAR21714.1 - 4.9 5.2 18.5 6.3 4.9 12.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CRAL_TRIO PF00650.15 CAR21715.1 - 6.4e-41 139.4 0.0 8.9e-41 139.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR21715.1 - 1.1e-12 47.8 1.5 4.4e-12 45.9 1.0 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CAR21715.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain EXOSC1 PF10447.4 CAR21716.1 - 1.6e-32 111.2 0.1 2.9e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 CAR21716.1 - 0.001 19.0 2.4 0.93 9.6 0.0 3.2 3 0 0 3 3 3 2 S1 RNA binding domain Globin PF00042.17 CAR21718.1 - 5.7e-06 26.6 0.0 1.8e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Globin Spc97_Spc98 PF04130.8 CAR21719.1 - 1.3e-81 274.5 9.1 1.9e-81 274.0 6.3 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Enolase_C PF00113.17 CAR21720.1 - 5.9e-152 504.7 0.1 7.6e-152 504.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CAR21720.1 - 3.7e-58 195.1 0.5 6.3e-58 194.4 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 CAR21720.1 - 0.0025 16.7 0.3 0.0052 15.7 0.0 1.5 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 CAR21720.1 - 0.031 14.2 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Enolase C-terminal domain-like MR_MLE PF01188.16 CAR21720.1 - 0.092 13.2 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Ctr PF04145.10 CAR21721.1 - 1.6e-28 99.6 15.3 4.6e-26 91.5 10.6 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Ni_hydr_CYTB PF01292.15 CAR21721.1 - 0.008 15.5 7.0 0.0086 15.4 4.8 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Tox-SGS PF15651.1 CAR21721.1 - 0.11 12.2 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin Tad PF13400.1 CAR21721.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.4 2 1 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like FMO-like PF00743.14 CAR21722.1 - 4e-42 144.1 0.0 2.5e-32 111.8 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CAR21722.1 - 3.4e-16 59.9 0.0 8.5e-15 55.3 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR21722.1 - 1.2e-13 51.1 0.8 1e-11 44.8 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 CAR21722.1 - 8e-07 28.2 0.1 0.043 12.7 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAR21722.1 - 1.6e-06 27.9 0.0 5.2e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CAR21722.1 - 3e-06 27.2 0.0 6.8e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAR21722.1 - 3.6e-05 22.9 0.1 0.00029 20.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 CAR21722.1 - 6.2e-05 22.0 0.6 0.022 13.6 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CAR21722.1 - 0.0022 16.5 0.0 0.025 13.0 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CAR21722.1 - 0.016 14.3 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 CAR21722.1 - 0.026 14.2 0.1 0.74 9.5 0.0 2.6 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 CAR21722.1 - 0.028 13.8 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 CAR21722.1 - 0.038 13.6 0.4 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CAR21722.1 - 0.069 13.2 0.3 4.4 7.4 0.0 2.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 CAR21722.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 CAR21722.1 - 0.13 11.2 0.0 0.3 10.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Fungal_trans PF04082.13 CAR21723.1 - 7.9e-30 103.5 0.2 1.3e-29 102.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR21723.1 - 1.8e-07 30.9 11.9 3.5e-07 29.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CAR21723.1 - 1.2 9.3 11.3 0.97 9.6 5.5 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Erv26 PF04148.8 CAR21724.1 - 1.4e-86 289.2 5.0 1.6e-86 289.0 3.4 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.8 CAR21724.1 - 0.012 15.6 1.6 0.023 14.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Cytochrom_C_asm PF01578.15 CAR21724.1 - 0.21 11.1 4.4 0.11 11.9 1.2 2.0 1 1 1 2 2 2 0 Cytochrome C assembly protein Pox_I1 PF03289.8 CAR21725.1 - 0.0038 16.1 0.1 0.0066 15.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus protein I1 RhoGAP PF00620.22 CAR21725.1 - 0.02 14.5 0.1 0.19 11.3 0.0 2.5 2 0 0 2 2 2 0 RhoGAP domain ING PF12998.2 CAR21725.1 - 0.73 10.1 9.1 1.2 9.4 1.5 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding 6PGD PF00393.14 CAR21726.1 - 2.6e-134 447.0 0.0 4e-134 446.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CAR21726.1 - 3.6e-52 176.4 0.0 5.3e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CAR21726.1 - 0.0028 18.0 0.1 0.005 17.2 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 CAR21726.1 - 0.1 12.6 0.1 0.75 9.8 0.0 2.4 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 CAR21726.1 - 0.13 12.3 0.1 0.47 10.5 0.1 1.8 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Virulence_fact PF13769.1 CAR21727.1 - 0.041 13.7 0.8 0.25 11.2 0.1 2.5 2 0 0 2 2 2 0 Virulence factor DUF342 PF03961.8 CAR21727.1 - 0.72 8.1 9.1 1.3 7.4 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FKBP_N PF01346.13 CAR21727.1 - 2.2 8.3 11.6 0.31 11.1 0.1 2.9 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Mito_carr PF00153.22 CAR21728.1 - 4.1e-64 212.3 0.0 2.2e-24 84.9 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.10 CAR21728.1 - 0.046 13.2 0.1 0.9 9.0 0.1 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI XPG_N PF00752.12 CAR21730.1 - 4.4e-36 123.1 0.0 1.1e-35 121.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CAR21730.1 - 6.8e-25 86.9 0.0 2.4e-24 85.2 0.0 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CAR21730.1 - 7.6e-05 22.8 0.0 0.00028 21.0 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Raptor_N PF14538.1 CAR21731.1 - 2.3e-65 219.1 0.0 2.3e-65 219.1 0.0 2.7 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain BBS2_Mid PF14783.1 CAR21731.1 - 3.8e-06 26.6 0.0 0.00011 21.9 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 CAR21731.1 - 1.2e-05 24.9 0.7 0.37 10.9 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat WD40 PF00400.27 CAR21731.1 - 0.00055 19.7 10.1 11 6.0 0.0 6.6 8 0 0 8 8 8 3 WD domain, G-beta repeat Elong_Iki1 PF10483.4 CAR21732.1 - 1e-80 271.1 0.4 1.2e-80 270.9 0.3 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Gpi16 PF04113.9 CAR21733.1 - 2.8e-191 636.4 0.0 3.6e-191 636.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HEAT_2 PF13646.1 CAR21734.1 - 5.3e-18 65.0 0.1 0.00057 20.1 0.0 7.4 5 4 3 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 CAR21734.1 - 2.8e-10 40.3 0.1 3.1 8.3 0.0 8.0 7 1 0 7 7 7 2 HEAT-like repeat HEAT PF02985.17 CAR21734.1 - 1.1e-09 37.4 9.7 1.3 9.2 0.0 9.2 10 0 0 10 10 10 2 HEAT repeat NUC173 PF08161.7 CAR21734.1 - 5e-06 26.0 0.3 0.073 12.4 0.0 4.1 4 0 0 4 4 4 2 NUC173 domain Adaptin_N PF01602.15 CAR21734.1 - 7.5e-06 24.5 0.2 0.042 12.1 0.0 4.5 4 1 1 5 5 5 1 Adaptin N terminal region Cnd1 PF12717.2 CAR21734.1 - 6.5e-05 22.8 2.3 7.8 6.3 0.1 6.0 4 3 3 7 7 7 1 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 CAR21734.1 - 0.00025 21.0 1.9 0.052 13.6 0.0 4.3 5 1 1 6 6 6 1 Protein of unknown function (DUF1546) Vac14_Fab1_bd PF12755.2 CAR21734.1 - 0.00096 19.4 0.5 13 6.2 0.0 4.8 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 CAR21734.1 - 0.11 11.1 0.9 17 3.9 0.0 3.5 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 CAR21735.1 - 5.7e-93 312.0 0.6 6.9e-93 311.7 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 CAR21735.1 - 5.9e-12 44.6 2.5 0.0021 17.9 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 CAR21735.1 - 1.2e-09 38.3 11.3 8e-05 22.8 0.2 5.6 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 CAR21735.1 - 5.3e-05 23.5 9.5 0.0096 16.3 0.2 4.1 5 0 0 5 5 5 2 HEAT-like repeat RasGEF_N_2 PF14663.1 CAR21735.1 - 0.0037 17.1 0.3 2.8 7.9 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd1 PF12717.2 CAR21735.1 - 0.031 14.1 1.8 0.18 11.6 0.0 2.9 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 CAR21735.1 - 0.073 12.4 0.0 4.7 6.4 0.0 2.7 1 1 1 2 2 2 0 CLASP N terminal Cohesin_HEAT PF12765.2 CAR21735.1 - 0.078 12.9 13.1 0.36 10.8 0.2 4.2 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion Aminotran_4 PF01063.14 CAR21736.1 - 2.3e-17 63.2 0.0 3.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV DUF4446 PF14584.1 CAR21736.1 - 0.0053 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) YozD PF14162.1 CAR21736.1 - 0.086 12.9 0.3 6.2 6.9 0.0 3.2 3 1 1 4 4 4 0 YozD-like protein Kdo PF06293.9 CAR21737.1 - 2.8e-08 33.0 0.0 4.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR21737.1 - 0.00021 21.1 0.1 0.0021 17.8 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAR21737.1 - 0.00023 20.5 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 CAR21737.1 - 0.00099 18.3 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 CAR21737.1 - 0.086 11.9 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase tRNA-synt_1g PF09334.6 CAR21738.1 - 1e-148 495.1 0.1 1.8e-148 494.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 CAR21738.1 - 2e-43 147.6 2.7 2e-43 147.6 1.9 1.9 2 0 0 2 2 2 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 CAR21738.1 - 5.1e-10 37.9 1.6 0.0005 18.1 0.0 3.0 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CAR21738.1 - 0.0092 15.1 0.0 0.037 13.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DEAD PF00270.24 CAR21739.1 - 5.4e-44 149.6 1.4 8e-44 149.1 0.1 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR21739.1 - 1.1e-21 76.4 0.0 2.4e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAR21739.1 - 1.4e-20 72.5 0.3 2.8e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SecA_DEAD PF07517.9 CAR21739.1 - 0.0036 16.6 0.0 0.011 15.0 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.10 CAR21739.1 - 0.0043 16.8 0.1 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Sec34 PF04136.10 CAR21739.1 - 0.038 13.6 0.1 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Sec34-like family PhoD PF09423.5 CAR21740.1 - 4e-07 28.9 0.0 7e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Pkinase PF00069.20 CAR21741.1 - 1.8e-51 174.8 0.2 3.6e-51 173.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21741.1 - 1.6e-23 83.0 0.3 1e-22 80.4 0.1 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR21741.1 - 0.036 13.0 0.1 0.42 9.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like GTP_cyclohydroI PF01227.17 CAR21742.1 - 1.4e-77 259.0 1.1 1.6e-77 258.8 0.8 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CAR21742.1 - 5.1e-06 26.3 0.0 1.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein OmpH PF03938.9 CAR21742.1 - 0.065 13.1 0.4 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DnaJ_CXXCXGXG PF00684.14 CAR21743.1 - 5.4e-05 23.1 7.4 0.046 13.7 0.5 2.3 2 0 0 2 2 2 2 DnaJ central domain HypA PF01155.14 CAR21743.1 - 0.18 11.4 2.5 1 9.0 0.2 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2318 PF10080.4 CAR21743.1 - 0.2 11.4 1.1 0.44 10.3 0.8 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Got1 PF04178.7 CAR21744.1 - 7.6e-20 71.1 13.2 8.9e-20 70.9 9.1 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 CAR21744.1 - 0.01 14.8 5.2 0.014 14.3 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF1129 PF06570.6 CAR21744.1 - 1.5 8.1 5.3 1.9 7.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF872 PF05915.7 CAR21744.1 - 6.2 6.7 9.3 0.77 9.6 2.6 2.3 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SdpI PF13630.1 CAR21744.1 - 8.5 6.1 16.8 2.1 8.1 2.2 2.4 2 1 0 2 2 2 0 SdpI/YhfL protein family AAA PF00004.24 CAR21745.1 - 3.9e-47 159.7 0.0 2.2e-42 144.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CAR21745.1 - 7.1e-06 26.0 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CAR21745.1 - 3e-05 24.1 0.0 0.0002 21.4 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 CAR21745.1 - 5.8e-05 22.5 0.0 0.00017 21.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 CAR21745.1 - 6.4e-05 22.7 0.0 0.00026 20.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 CAR21745.1 - 9.9e-05 22.1 0.0 0.0004 20.2 0.0 2.1 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.1 CAR21745.1 - 0.00018 21.6 0.1 0.0035 17.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CAR21745.1 - 0.0005 20.1 0.0 0.091 12.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 CAR21745.1 - 0.0016 18.3 0.0 0.011 15.6 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_19 PF13245.1 CAR21745.1 - 0.0021 17.7 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CAR21745.1 - 0.0036 16.7 0.1 0.012 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CAR21745.1 - 0.006 16.4 0.0 0.027 14.2 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 CAR21745.1 - 0.0082 15.6 0.0 0.47 9.9 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.8 CAR21745.1 - 0.0099 14.6 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CAR21745.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAR21745.1 - 0.014 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 CAR21745.1 - 0.026 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CAR21745.1 - 0.03 13.4 0.0 0.084 12.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CAR21745.1 - 0.031 14.5 1.3 0.21 11.9 0.0 3.2 4 0 0 4 4 2 0 AAA domain ABC_tran PF00005.22 CAR21745.1 - 0.032 14.5 0.0 0.032 14.5 0.0 2.6 2 1 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.12 CAR21745.1 - 0.033 13.0 0.1 0.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 CAR21745.1 - 0.043 13.0 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.1 CAR21745.1 - 0.043 14.6 0.0 0.043 14.6 0.0 3.2 3 1 0 3 3 1 0 AAA domain RuvB_N PF05496.7 CAR21745.1 - 0.047 12.7 0.0 0.089 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 CAR21745.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Amidase PF01425.16 CAR21746.1 - 7.7e-113 377.6 0.0 9.3e-113 377.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Dynamitin PF04912.9 CAR21747.1 - 1.5e-14 53.6 31.5 1.3e-11 43.9 21.8 2.5 1 1 0 1 1 1 1 Dynamitin AF0941-like PF14591.1 CAR21747.1 - 0.019 15.0 0.9 0.019 15.0 0.6 3.6 2 1 1 4 4 4 0 AF0941-like Gal4_dimer PF03902.8 CAR21747.1 - 0.055 13.4 0.5 15 5.6 0.1 3.4 2 0 0 2 2 2 0 Gal4-like dimerisation domain Tropomyosin_1 PF12718.2 CAR21747.1 - 0.088 12.6 23.8 0.48 10.2 7.8 2.7 2 1 0 2 2 2 0 Tropomyosin like Mt_ATP-synt_D PF05873.7 CAR21747.1 - 0.17 11.4 8.9 0.12 11.9 1.0 3.1 1 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) NPV_P10 PF05531.7 CAR21747.1 - 0.18 12.1 12.6 4.7 7.5 0.8 4.9 2 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DHC PF09626.5 CAR21747.1 - 0.48 11.1 2.4 18 6.0 0.4 2.6 1 1 1 2 2 2 0 Dihaem cytochrome c Reo_sigmaC PF04582.7 CAR21747.1 - 0.91 8.6 16.6 0.18 10.9 1.4 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF948 PF06103.6 CAR21747.1 - 4.1 7.3 14.4 7 6.5 0.0 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.5 CAR21747.1 - 8.6 6.4 30.9 7.4 6.6 3.2 3.6 1 1 1 3 3 3 0 Cortexillin I, coiled coil Sec63 PF02889.11 CAR21748.1 - 4.1e-138 459.8 0.8 2.4e-91 306.2 0.1 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CAR21748.1 - 8.7e-53 178.2 1.5 7.1e-28 97.1 0.5 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 CAR21748.1 - 1.3e-21 77.2 0.0 2.9e-10 40.2 0.1 3.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CAR21748.1 - 2.3e-18 65.7 0.0 7e-08 32.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAR21748.1 - 8.7e-07 29.1 0.9 0.094 12.8 0.1 4.2 3 1 0 3 3 3 2 AAA domain AAA PF00004.24 CAR21748.1 - 1e-06 28.9 3.5 0.061 13.5 0.0 5.0 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 CAR21748.1 - 1.1e-06 27.7 0.2 0.0018 17.1 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 CAR21748.1 - 1.6e-05 24.2 0.0 0.015 14.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 CAR21748.1 - 6.7e-05 22.5 0.0 0.036 13.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 CAR21748.1 - 0.0031 16.9 0.2 1.6 8.1 0.0 4.1 5 0 0 5 5 5 1 IstB-like ATP binding protein DUF2361 PF10153.4 CAR21749.1 - 1e-28 99.7 14.7 1e-28 99.7 10.2 2.3 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) AbbA_antirepres PF14156.1 CAR21749.1 - 0.018 14.6 1.4 0.04 13.5 0.6 1.8 2 0 0 2 2 2 0 Antirepressor AbbA DUF2406 PF10295.4 CAR21750.1 - 5.5e-25 87.6 0.1 1e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Fungal_trans PF04082.13 CAR21751.1 - 9e-17 60.7 0.9 1.6e-16 59.9 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR21751.1 - 4.5e-09 36.0 13.7 8.9e-09 35.1 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 CAR21752.1 - 1e-69 234.5 14.8 1.4e-69 234.0 10.2 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF202 PF02656.10 CAR21752.1 - 9.4 6.5 9.3 0.66 10.2 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Aminotran_1_2 PF00155.16 CAR21753.1 - 4.1e-61 206.9 0.0 4.9e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CAR21753.1 - 0.0031 15.8 0.0 0.0061 14.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Peptidase_S10 PF00450.17 CAR21754.1 - 4.9e-131 437.7 1.2 6.1e-131 437.4 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 CAR21754.1 - 3.6e-19 68.9 0.1 6.5e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 CAR21754.1 - 0.005 16.7 0.0 0.092 12.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF3591 PF12157.3 CAR21756.1 - 7e-199 660.9 0.2 7e-199 660.9 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CAR21756.1 - 3.8e-06 26.4 1.0 8.5e-06 25.3 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Rtt102p PF09510.5 CAR21757.1 - 1.4e-25 89.7 1.0 1.4e-25 89.7 0.7 1.6 2 0 0 2 2 2 1 Rtt102p-like transcription regulator protein RNase_T PF00929.19 CAR21758.1 - 7e-27 94.7 0.1 2e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Exonuclease GATase_2 PF00310.16 CAR21760.1 - 1.1e-25 90.0 0.1 2.3e-20 72.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CAR21760.1 - 6e-14 52.1 0.0 1.6e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CAR21760.1 - 2.1e-12 46.8 0.1 4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 CAR21760.1 - 8e-12 44.9 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CAR21760.1 - 2.4e-05 23.1 0.0 3.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PTSIIB_sorb PF03830.10 CAR21760.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component ABC_tran PF00005.22 CAR21761.1 - 1.7e-35 122.3 0.0 3.6e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CAR21761.1 - 8e-35 120.5 17.1 1e-34 120.2 11.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CAR21761.1 - 1.2e-09 37.7 0.0 1.6e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CAR21761.1 - 2.9e-09 37.3 0.0 0.00016 21.7 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_29 PF13555.1 CAR21761.1 - 0.00042 19.7 0.2 0.0011 18.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CAR21761.1 - 0.0012 18.8 0.0 0.0035 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 CAR21761.1 - 0.0023 16.6 0.1 0.055 12.0 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 CAR21761.1 - 0.0025 18.6 0.1 0.0084 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CAR21761.1 - 0.0061 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 CAR21761.1 - 0.0077 16.3 0.0 0.031 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAR21761.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 CAR21761.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 CAR21761.1 - 0.034 14.0 0.0 0.2 11.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.1 CAR21761.1 - 0.045 14.0 0.2 0.045 14.0 0.1 2.9 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 CAR21761.1 - 0.058 13.6 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CAR21761.1 - 0.072 12.2 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 CAR21761.1 - 0.079 12.5 0.2 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CAR21761.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain SbcCD_C PF13558.1 CAR21761.1 - 0.17 11.8 0.5 1.1 9.2 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Proteasome PF00227.21 CAR21762.1 - 2.1e-46 157.6 0.0 2.5e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR21762.1 - 6e-13 47.8 1.1 1.9e-12 46.2 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3336 PF11815.3 CAR21763.1 - 2.1e-28 98.6 0.0 3.9e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CAR21763.1 - 5.8e-08 32.9 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DnaJ PF00226.26 CAR21765.1 - 3.5e-18 65.0 0.8 3.5e-18 65.0 0.5 2.6 2 0 0 2 2 2 1 DnaJ domain SURF4 PF02077.10 CAR21766.1 - 2.7e-92 308.9 11.4 3.3e-92 308.6 7.9 1.1 1 0 0 1 1 1 1 SURF4 family IPP-2 PF04979.9 CAR21767.1 - 1.8e-10 41.1 6.5 1.8e-10 41.1 4.5 1.9 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Uds1 PF15456.1 CAR21767.1 - 1.1 9.2 8.6 3.5 7.6 0.5 2.1 2 0 0 2 2 2 0 Up-regulated During Septation SR-25 PF10500.4 CAR21767.1 - 7.7 5.9 14.2 0.14 11.5 2.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltrn_RNA_3 PF02598.12 CAR21768.1 - 4.2e-91 305.3 0.0 5.7e-91 304.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase Glyco_hydro_17 PF00332.13 CAR21769.1 - 1.4e-67 227.9 0.5 1.6e-67 227.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 eIF-3c_N PF05470.7 CAR21770.1 - 4.5e-155 517.1 11.8 5.5e-119 397.9 0.4 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CAR21770.1 - 5.3e-16 58.8 1.0 3.6e-15 56.1 0.0 3.0 3 1 0 3 3 3 1 PCI domain DUF2034 PF10356.4 CAR21770.1 - 0.0028 16.8 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) TPR_11 PF13414.1 CAR21770.1 - 0.0063 16.1 0.5 1.1 8.9 0.0 3.9 4 0 0 4 4 4 1 TPR repeat Fumerase PF05681.9 CAR21770.1 - 0.045 12.8 0.3 0.073 12.1 0.2 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) HTH_Tnp_ISL3 PF13542.1 CAR21770.1 - 0.047 12.8 0.1 0.87 8.8 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.11 CAR21770.1 - 0.072 12.4 0.5 1.9 7.8 0.0 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 TPR_14 PF13428.1 CAR21770.1 - 0.11 13.2 0.8 6 7.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_membrane PF00664.18 CAR21771.1 - 6.7e-67 225.7 41.3 2.2e-38 132.2 11.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAR21771.1 - 3.3e-45 153.7 1.0 1.5e-27 96.5 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAR21771.1 - 1.6e-12 48.0 0.0 0.0024 17.9 0.0 4.5 2 2 2 4 4 4 3 AAA domain SMC_N PF02463.14 CAR21771.1 - 3.2e-08 33.0 5.9 0.014 14.6 0.5 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR21771.1 - 2.3e-06 27.0 2.2 0.043 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CAR21771.1 - 2.6e-05 25.0 0.7 0.086 13.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CAR21771.1 - 0.0001 21.7 0.1 0.17 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAR21771.1 - 0.00011 21.3 0.6 0.086 12.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 CAR21771.1 - 0.00012 21.0 0.4 0.039 12.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 CAR21771.1 - 0.0004 20.6 0.1 0.26 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CAR21771.1 - 0.00053 19.9 0.4 0.29 11.0 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 CAR21771.1 - 0.0011 19.2 15.5 0.091 13.0 0.0 3.5 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 CAR21771.1 - 0.0046 17.4 2.5 1.5 9.3 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 CAR21771.1 - 0.0073 15.1 1.4 0.27 9.9 0.1 2.3 2 0 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 CAR21771.1 - 0.0081 15.2 0.4 1 8.4 0.0 3.0 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 CAR21771.1 - 0.017 15.2 6.7 1.1 9.4 0.7 3.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAR21771.1 - 0.022 14.3 8.5 0.95 9.0 0.1 3.6 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 CAR21771.1 - 0.024 14.7 0.2 8.8 6.5 0.0 3.2 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.20 CAR21771.1 - 0.027 13.9 0.3 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 CAR21771.1 - 0.029 14.3 1.5 1 9.3 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 CAR21771.1 - 0.051 13.2 2.4 2.8 7.6 0.1 3.3 5 0 0 5 5 3 0 NTPase ATP_bind_1 PF03029.12 CAR21771.1 - 0.092 12.2 3.0 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CAR21771.1 - 0.71 9.3 7.8 1.1 8.6 0.0 3.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family Fungal_trans PF04082.13 CAR21772.1 - 1.3e-18 66.8 0.1 3e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3839 PF12943.2 CAR21772.1 - 0.082 12.0 0.0 0.4 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3839) HEAT PF02985.17 CAR21773.1 - 4.1e-20 69.9 2.0 0.00098 19.0 0.0 9.8 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.1 CAR21773.1 - 1.9e-18 66.5 0.2 6.4e-09 35.9 0.0 6.0 5 2 1 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CAR21773.1 - 2e-18 66.2 6.5 6.1e-08 32.9 0.0 9.8 9 1 2 11 11 11 2 HEAT-like repeat RIX1 PF08167.7 CAR21773.1 - 7.8e-12 45.1 2.3 0.0011 18.6 0.1 5.5 4 2 1 5 5 5 2 rRNA processing/ribosome biogenesis Arm PF00514.18 CAR21773.1 - 7.5e-07 28.7 4.2 0.16 11.8 0.0 5.5 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CAR21773.1 - 1.2e-06 28.8 0.0 0.04 14.2 0.0 5.5 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 CAR21773.1 - 4.3e-06 25.7 6.6 0.0098 14.6 0.4 4.1 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 CAR21773.1 - 0.0002 20.7 0.1 0.039 13.2 0.1 3.6 4 0 0 4 4 4 1 CLASP N terminal DNA_alkylation PF08713.6 CAR21773.1 - 0.0087 15.5 0.0 0.068 12.6 0.0 2.4 2 0 0 2 2 2 1 DNA alkylation repair enzyme ParcG PF10274.4 CAR21773.1 - 0.028 14.3 3.4 0.37 10.6 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein G-patch PF01585.18 CAR21774.1 - 1.1e-10 41.1 0.1 2.6e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CAR21774.1 - 2.3e-05 24.1 0.3 2.3e-05 24.1 0.2 4.6 2 1 0 2 2 2 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 CAR21774.1 - 6.7 5.0 62.8 10 4.4 43.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_hydro_72 PF03198.9 CAR21775.1 - 3.1e-141 469.9 7.7 4.1e-141 469.4 5.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CAR21775.1 - 1.4e-24 86.3 4.6 4e-24 84.9 3.2 1.8 1 0 0 1 1 1 1 X8 domain Rep_1 PF01446.12 CAR21775.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein DUF1644 PF07800.7 CAR21775.1 - 0.26 11.1 4.2 2 8.2 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1644) Glyco_hydro_72 PF03198.9 CAR21776.1 - 4.9e-143 475.8 11.6 7.4e-143 475.2 8.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CAR21776.1 - 6.9e-27 93.7 6.6 2.3e-26 92.0 4.6 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 CAR21776.1 - 5e-05 22.3 0.4 8e-05 21.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Pex14_N PF04695.8 CAR21776.1 - 0.37 10.8 5.3 0.74 9.8 1.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glucan_synthase PF02364.10 CAR21777.1 - 0 1369.8 1.5 0 1369.8 1.0 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CAR21777.1 - 4.3e-38 129.8 0.0 1.2e-37 128.3 0.0 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3817 PF12823.2 CAR21777.1 - 0.0003 21.1 5.3 0.0003 21.1 3.7 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3817) Glyco_hydro_17 PF00332.13 CAR21778.1 - 4.2e-07 29.3 0.3 4.2e-07 29.3 0.2 2.3 2 2 0 2 2 2 1 Glycosyl hydrolases family 17 DUF3337 PF11816.3 CAR21778.1 - 0.066 12.5 3.3 0.092 12.1 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Macoilin PF09726.4 CAR21778.1 - 4.2 5.5 22.3 5.5 5.1 15.4 1.1 1 0 0 1 1 1 0 Transmembrane protein MA3 PF02847.12 CAR21779.1 - 3.8e-19 68.4 0.0 1.9e-18 66.2 0.0 2.3 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 CAR21779.1 - 1.1e-11 44.5 4.1 1.3e-11 44.2 2.1 1.6 2 0 0 2 2 2 1 MIF4G domain RE_TdeIII PF09520.5 CAR21779.1 - 0.032 13.5 0.1 0.093 12.0 0.0 1.8 2 0 0 2 2 2 0 Type II restriction endonuclease, TdeIII CTP_transf_2 PF01467.21 CAR21780.1 - 4.1e-14 52.9 0.0 7.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase USP7_C2 PF14533.1 CAR21781.1 - 6.7e-56 189.0 6.7 3.6e-55 186.6 1.6 3.5 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 CAR21781.1 - 1.3e-51 175.3 0.8 2.8e-51 174.2 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CAR21781.1 - 1.8e-32 112.5 0.8 1.3e-31 109.7 0.1 2.5 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 CAR21781.1 - 1.3e-29 103.5 0.0 2.5e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CAR21781.1 - 1e-12 48.3 0.5 5.5e-12 45.9 0.1 2.6 2 0 0 2 2 2 1 MATH domain Epimerase PF01370.16 CAR21781.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RNA12 PF10443.4 CAR21782.1 - 3.3e-166 553.0 0.3 1.3e-165 551.1 0.1 1.9 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 CAR21782.1 - 1.9e-05 24.1 0.0 6.3e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 CAR21782.1 - 0.0016 18.1 0.6 0.021 14.5 0.0 3.0 2 1 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 CAR21782.1 - 0.0019 18.1 0.1 0.019 14.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CAR21782.1 - 0.019 15.1 0.1 11 6.1 0.0 3.5 2 1 0 2 2 2 0 AAA domain Hydantoinase_B PF02538.9 CAR21783.1 - 4.5e-217 721.4 0.1 5.9e-217 721.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CAR21783.1 - 1.8e-91 306.2 0.1 3.5e-91 305.3 0.1 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CAR21783.1 - 9.4e-51 171.7 0.1 5.6e-49 166.0 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 CAR21784.1 - 4.9e-41 140.6 25.0 6.3e-41 140.2 17.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SPC25 PF06703.6 CAR21784.1 - 1.2 8.7 4.5 26 4.3 0.7 2.9 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Fungal_trans PF04082.13 CAR21785.1 - 3.1e-14 52.4 3.6 8.2e-14 51.0 2.5 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR21785.1 - 0.00069 19.4 12.9 0.0013 18.5 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.7 CAR21786.1 - 6.2e-54 181.5 0.0 8e-54 181.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MFS_1 PF07690.11 CAR21787.1 - 6.9e-39 133.5 49.6 1.4e-37 129.2 31.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR21787.1 - 4.5e-13 48.2 19.6 1.5e-12 46.5 13.6 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ferritin_2 PF13668.1 CAR21788.1 - 2.2e-42 144.2 1.5 3.2e-42 143.7 1.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain PHO4 PF01384.15 CAR21789.1 - 1.5e-114 382.0 15.6 2.1e-114 381.5 10.8 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF4131 PF13567.1 CAR21789.1 - 6.8 6.0 17.2 0.72 9.2 3.6 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUP PF00674.13 CAR21790.1 - 4.2e-18 65.2 1.0 6.1e-18 64.7 0.3 1.6 1 1 0 1 1 1 1 DUP family PepSY_TM PF03929.11 CAR21790.1 - 0.051 13.9 0.4 0.17 12.3 0.3 1.9 1 0 0 1 1 1 0 PepSY-associated TM helix DUP PF00674.13 CAR21791.1 - 9.1e-15 54.5 0.1 1.6e-14 53.7 0.1 1.5 1 1 0 1 1 1 1 DUP family DUF4111 PF13427.1 CAR21791.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) DUP PF00674.13 CAR21792.1 - 1.8e-12 47.1 0.0 2.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 DUP family DUP PF00674.13 CAR21793.1 - 5.5e-12 45.5 0.7 8.6e-12 44.9 0.2 1.5 2 0 0 2 2 2 1 DUP family DEAD PF00270.24 CAR21794.1 - 9.9e-12 44.6 0.0 2.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR21794.1 - 1.7e-07 31.0 0.0 3.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR21794.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAR21794.1 - 0.1 12.7 0.0 1.1 9.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain NUP PF06516.6 CAR21795.1 - 1.5e-61 207.9 0.0 1.8e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) MFS_1 PF07690.11 CAR21796.1 - 1.9e-36 125.5 26.3 1.9e-36 125.5 18.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.3 CAR21796.1 - 0.02 14.1 4.1 0.14 11.3 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) CRPA PF05745.6 CAR21796.1 - 0.074 12.8 1.1 0.35 10.6 0.2 2.5 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) ESSS PF10183.4 CAR21796.1 - 0.11 12.9 0.1 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF912 PF06024.7 CAR21796.1 - 0.17 11.9 1.4 0.96 9.5 0.0 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Helicase_C PF00271.26 CAR21797.1 - 3.7e-12 45.9 0.0 9.5e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR21797.1 - 2.3e-09 36.9 0.0 9.7e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sir1 PF11603.3 CAR21797.1 - 0.012 15.7 0.4 0.063 13.4 0.0 2.4 2 0 0 2 2 2 0 Regulatory protein Sir1 MFS_1 PF07690.11 CAR21798.1 - 3e-09 36.0 55.8 3.1e-07 29.4 37.4 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR21798.1 - 9.8e-06 24.3 11.2 9.8e-06 24.3 7.8 3.3 4 1 1 5 5 5 1 Sugar (and other) transporter Amidase PF01425.16 CAR21799.1 - 2.6e-76 257.2 0.0 2.9e-74 250.5 0.0 2.1 2 0 0 2 2 2 2 Amidase Arylsulfotran_2 PF14269.1 CAR21800.1 - 1.5e-70 237.7 3.8 2e-70 237.3 2.6 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 CAR21800.1 - 1e-16 60.5 1.8 2.8e-16 59.0 1.2 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Acetyltransf_3 PF13302.1 CAR21801.1 - 1.8e-12 47.5 0.0 2.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAR21801.1 - 0.00026 20.9 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR21801.1 - 0.0025 17.8 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CAR21801.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUP PF00674.13 CAR21802.1 - 1.4e-17 63.5 0.3 4.1e-17 62.0 0.0 1.7 1 1 1 2 2 2 1 DUP family FeoB_C PF07664.7 CAR21802.1 - 0.19 11.1 1.3 0.31 10.4 0.9 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus PhyH PF05721.8 CAR21803.1 - 3.3e-19 69.7 0.0 4.5e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 CAR21804.1 - 8.6e-15 54.2 28.7 8.6e-15 54.2 19.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 CAR21805.1 - 5.9e-21 74.5 11.0 9.2e-21 73.9 7.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.17 CAR21806.1 - 6.7e-57 192.8 0.5 7.7e-57 192.6 0.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter His_Phos_2 PF00328.17 CAR21807.1 - 6.5e-52 176.9 0.0 7.9e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 CAR21807.1 - 0.031 14.3 0.0 0.069 13.2 0.0 1.5 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) HRXXH PF13933.1 CAR21808.1 - 2.1e-84 282.7 0.2 2.5e-84 282.5 0.1 1.0 1 0 0 1 1 1 1 Putative peptidase family DsbB PF02600.11 CAR21808.1 - 0.044 13.5 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB Aspzincin_M35 PF14521.1 CAR21808.1 - 0.083 13.4 0.1 5.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Flocculin PF00624.13 CAR21809.1 - 0 1610.3 1440.2 3.1e-15 55.7 19.8 43.8 44 0 0 44 44 44 37 Flocculin repeat Candida_ALS_N PF11766.3 CAR21809.1 - 1.3e-34 119.2 9.2 1.3e-34 119.2 6.4 3.2 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding Sugar_tr PF00083.19 CAR21810.1 - 5.8e-168 559.1 34.4 6.6e-168 558.9 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR21810.1 - 3.4e-30 104.9 32.0 8.6e-29 100.3 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LMF1 PF06762.9 CAR21810.1 - 0.0022 16.8 1.1 0.0037 16.1 0.7 1.3 1 0 0 1 1 1 1 Lipase maturation factor P16-Arc PF04699.9 CAR21811.1 - 0.094 12.7 1.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) adh_short PF00106.20 CAR21812.1 - 1.8e-26 93.0 2.8 1.2e-23 83.8 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CAR21812.1 - 1.3e-09 38.0 1.9 5.5e-09 35.9 0.2 2.1 1 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CAR21812.1 - 1.5e-09 38.0 0.5 5.3e-07 29.6 0.2 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CAR21812.1 - 5.5e-08 32.5 0.0 6.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAR21812.1 - 1.2e-05 25.3 0.1 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CAR21812.1 - 0.0023 16.6 0.4 0.0024 16.6 0.3 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Mannitol_dh PF01232.18 CAR21812.1 - 0.0067 16.3 0.0 0.037 13.9 0.0 2.0 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain Eno-Rase_NADH_b PF12242.3 CAR21812.1 - 0.017 14.8 0.6 0.055 13.2 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_tran_WecB PF03808.8 CAR21812.1 - 0.017 14.5 0.1 0.12 11.7 0.0 2.3 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_4 PF07993.7 CAR21812.1 - 0.11 11.4 0.1 0.89 8.4 0.1 2.0 1 1 0 1 1 1 0 Male sterility protein NmrA PF05368.8 CAR21812.1 - 0.12 11.5 0.5 0.23 10.7 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family ADK PF00406.17 CAR21813.1 - 7.1e-47 159.0 0.0 9.2e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CAR21813.1 - 1.3e-09 38.4 0.0 2.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR21813.1 - 1.5e-06 28.1 0.0 3.5e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CAR21813.1 - 1.6e-06 27.6 0.1 0.012 15.0 0.0 2.2 1 1 1 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 CAR21813.1 - 1.2e-05 26.0 0.0 1.8e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR21813.1 - 0.00054 19.1 0.0 0.00069 18.7 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin SRP54 PF00448.17 CAR21813.1 - 0.014 14.8 0.0 0.049 13.0 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CAR21813.1 - 0.13 12.0 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain TPR_2 PF07719.12 CAR21815.1 - 8.7e-36 118.9 8.4 0.002 17.9 0.0 10.8 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_1 PF00515.23 CAR21815.1 - 3.7e-34 114.9 12.0 7.2e-05 22.2 0.0 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 CAR21815.1 - 5.6e-34 115.6 11.9 1.5e-08 34.1 0.0 7.5 5 1 3 8 8 8 8 TPR repeat Apc3 PF12895.2 CAR21815.1 - 4.4e-29 100.4 21.2 7.5e-23 80.4 0.1 6.3 3 1 5 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CAR21815.1 - 2.7e-22 76.8 13.5 0.00018 21.0 0.1 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 CAR21815.1 - 3.8e-22 77.9 13.6 4.9e-08 32.8 0.1 8.8 5 3 5 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR21815.1 - 3.8e-20 72.0 0.0 2.3e-05 24.9 0.0 7.0 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAR21815.1 - 9.9e-20 70.6 5.3 0.00015 22.0 0.1 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAR21815.1 - 1.2e-18 65.8 0.1 0.0061 17.0 0.1 8.4 6 2 4 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 CAR21815.1 - 1.7e-17 61.7 8.3 0.00026 20.5 0.0 8.0 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAR21815.1 - 1.9e-14 52.5 2.6 0.31 11.3 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 CAR21815.1 - 2.1e-09 37.2 9.4 2 9.0 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAR21815.1 - 1.9e-08 33.9 2.6 0.27 11.2 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR21815.1 - 2.6e-08 33.5 0.2 1e-05 25.2 0.2 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 CAR21815.1 - 1.6e-05 24.6 1.4 2.1 8.2 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Coatomer_E PF04733.9 CAR21815.1 - 0.00026 20.2 1.2 2.7 7.0 0.0 5.3 5 2 2 7 7 7 1 Coatomer epsilon subunit PPTA PF01239.17 CAR21815.1 - 0.07 12.5 1.7 0.54 9.6 0.1 3.1 4 0 0 4 4 3 0 Protein prenyltransferase alpha subunit repeat DUF3856 PF12968.2 CAR21815.1 - 0.07 12.9 1.0 3.7 7.3 0.0 3.4 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) YagB_YeeU_YfjZ PF06154.6 CAR21815.1 - 0.094 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 YagB/YeeU/YfjZ family AlaDh_PNT_N PF05222.10 CAR21816.1 - 4.4e-28 97.9 0.0 6.8e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CAR21816.1 - 4e-16 59.0 0.1 5.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.27 CAR21817.1 - 3.1e-30 102.9 5.2 1.7e-07 30.8 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CAR21817.1 - 5.3e-07 28.7 1.4 1 8.0 0.0 4.2 2 1 2 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 CAR21817.1 - 8.8e-06 24.1 0.7 0.023 12.8 0.3 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 CAR21817.1 - 0.0038 16.9 1.8 7.6 6.3 0.0 4.1 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DUF4598 PF15370.1 CAR21817.1 - 0.0079 16.4 4.4 0.02 15.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Ank PF00023.25 CAR21818.1 - 1.2e-14 53.2 0.1 2.9e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CAR21818.1 - 1e-10 41.8 0.2 2.2e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAR21818.1 - 1.7e-10 41.1 0.2 0.00064 20.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAR21818.1 - 3.7e-09 36.5 0.2 2.2e-05 24.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR21818.1 - 4.8e-09 35.6 0.3 0.002 18.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 CAR21818.1 - 2e-08 34.0 0.7 7.7e-08 32.2 0.1 2.2 2 0 0 2 2 2 1 IPT/TIG domain PPTA PF01239.17 CAR21819.1 - 4.6e-40 133.3 21.3 3.7e-09 35.5 0.2 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.26 CAR21819.1 - 0.098 12.4 0.7 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 DnaJ domain DSPc PF00782.15 CAR21820.1 - 9.1e-25 86.7 0.3 1.2e-23 83.1 0.2 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR21820.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.9 CAR21820.1 - 0.0034 17.3 1.1 0.025 14.5 0.7 2.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PTPlike_phytase PF14566.1 CAR21820.1 - 0.019 14.9 0.0 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate Eapp_C PF10238.4 CAR21820.1 - 0.17 11.7 2.0 11 5.9 0.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein Apc15p PF05841.6 CAR21821.1 - 4.7e-23 82.2 1.7 6.2e-23 81.8 0.3 1.8 2 0 0 2 2 2 1 Apc15p protein Biotin_carb_C PF02785.14 CAR21821.1 - 0.09 12.7 0.0 0.39 10.7 0.0 1.9 1 1 0 1 1 1 0 Biotin carboxylase C-terminal domain DUF1748 PF08520.5 CAR21822.1 - 7.6e-08 31.8 0.1 1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.27 CAR21823.1 - 2e-14 52.8 0.3 5.7e-06 26.0 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Lactonase PF10282.4 CAR21823.1 - 0.0025 16.9 0.0 0.013 14.5 0.0 2.3 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller AAA_12 PF13087.1 CAR21824.1 - 2.8e-58 196.5 0.0 6.4e-58 195.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR21824.1 - 5.5e-55 186.5 0.5 9.2e-55 185.7 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR21824.1 - 4.3e-15 55.2 0.1 1.8e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CAR21824.1 - 7.8e-12 45.1 0.0 2.1e-09 37.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CAR21824.1 - 3.3e-08 33.3 0.3 0.21 11.0 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CAR21824.1 - 9.5e-07 28.4 0.0 3.8e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CAR21824.1 - 1.5e-05 25.1 0.3 0.00066 19.8 0.1 3.2 3 1 0 3 3 2 1 AAA domain DEAD PF00270.24 CAR21824.1 - 2.1e-05 24.1 1.8 0.00085 18.8 0.0 2.5 2 1 0 3 3 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CAR21824.1 - 4.4e-05 23.4 0.0 9.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 CAR21824.1 - 0.00042 19.9 0.0 0.0018 17.9 0.0 2.3 2 1 0 2 2 2 1 Helicase IstB_IS21 PF01695.12 CAR21824.1 - 0.0005 19.5 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 CAR21824.1 - 0.00059 19.3 0.0 0.0024 17.3 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 CAR21824.1 - 0.0012 18.8 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 CAR21824.1 - 0.0015 17.8 0.0 0.004 16.4 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 CAR21824.1 - 0.0019 17.2 0.3 0.024 13.6 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF853 PF05872.7 CAR21824.1 - 0.0042 15.5 0.0 0.0069 14.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) PIF1 PF05970.9 CAR21824.1 - 0.0055 15.6 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase AAA PF00004.24 CAR21824.1 - 0.008 16.3 0.2 0.029 14.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 CAR21824.1 - 0.011 14.3 0.0 0.021 13.4 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Flavi_DEAD PF07652.9 CAR21824.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain UvrD_C_2 PF13538.1 CAR21824.1 - 0.013 15.6 0.0 0.066 13.3 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 CAR21824.1 - 0.024 15.4 0.2 0.12 13.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CAR21824.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAR21824.1 - 0.098 12.0 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CAR21824.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CAR21824.1 - 0.15 10.8 0.5 0.33 9.6 0.0 1.7 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 CAR21824.1 - 0.17 12.2 2.3 0.87 9.8 0.5 2.7 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.1 CAR21824.1 - 2.1 8.6 9.1 1.6 9.0 0.0 2.5 1 1 0 2 2 2 0 AAA domain Mt_ATP-synt_D PF05873.7 CAR21825.1 - 1.8e-17 63.4 3.8 2.3e-17 63.1 2.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) EzrA PF06160.7 CAR21825.1 - 0.011 13.9 4.6 0.015 13.4 1.7 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA LTXXQ PF07813.7 CAR21825.1 - 0.016 15.6 1.3 3.7 8.0 0.4 2.2 2 0 0 2 2 2 0 LTXXQ motif family protein Dor1 PF04124.7 CAR21825.1 - 0.025 13.0 1.9 0.032 12.6 1.3 1.2 1 0 0 1 1 1 0 Dor1-like family DUF4201 PF13870.1 CAR21825.1 - 0.034 13.5 1.8 0.13 11.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Lipase PF00151.14 CAR21825.1 - 0.092 11.9 0.2 0.11 11.7 0.2 1.1 1 0 0 1 1 1 0 Lipase DUF4325 PF14213.1 CAR21825.1 - 0.14 11.8 0.6 0.31 10.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) MutS_IV PF05190.13 CAR21825.1 - 0.4 10.8 3.3 1.5 9.0 2.3 2.1 1 1 0 1 1 1 0 MutS family domain IV TPR_MLP1_2 PF07926.7 CAR21825.1 - 1.7 8.3 8.4 8.9 6.0 1.5 2.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fungal_trans PF04082.13 CAR21826.1 - 1.4e-24 86.4 0.0 2.1e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR21826.1 - 2.3e-09 37.0 8.3 3.9e-09 36.2 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.3 CAR21827.1 - 1.1e-90 304.0 4.2 1.1e-90 304.0 2.9 2.4 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Fungal_trans PF04082.13 CAR21829.1 - 8.3e-25 87.1 0.3 8.3e-25 87.1 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR21829.1 - 6.7e-06 25.9 8.4 1.3e-05 25.0 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.7 CAR21830.1 - 5.6e-71 237.3 5.8 6.2e-71 237.2 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.14 CAR21831.1 - 1.5e-41 140.0 18.0 1.7e-13 50.2 0.1 5.2 5 0 0 5 5 5 4 FF domain WW PF00397.21 CAR21831.1 - 1.2e-17 63.4 16.1 1.6e-09 37.4 1.0 3.0 3 0 0 3 3 3 2 WW domain PQQ PF01011.16 CAR21831.1 - 0.0061 16.0 0.4 4.4 7.0 0.1 2.4 2 0 0 2 2 2 2 PQQ enzyme repeat Plasmid_parti PF01672.11 CAR21831.1 - 0.031 14.6 1.9 0.56 10.6 0.2 3.0 2 0 0 2 2 2 0 Putative plasmid partition protein RNase_E_G PF10150.4 CAR21831.1 - 0.36 9.9 7.5 2.2 7.4 0.6 3.2 3 1 0 3 3 3 0 Ribonuclease E/G family Peptidase_S24 PF00717.18 CAR21832.1 - 3.8e-08 32.8 0.1 8.1e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like NAD_binding_10 PF13460.1 CAR21833.1 - 2.4e-28 99.4 0.1 2.7e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CAR21833.1 - 1.7e-11 43.8 0.0 3.7e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CAR21833.1 - 4.9e-09 35.3 0.4 6.6e-09 34.8 0.3 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CAR21833.1 - 8e-06 25.4 0.1 0.00064 19.2 0.0 2.7 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 CAR21833.1 - 3.6e-05 23.6 0.1 0.0001 22.1 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 CAR21833.1 - 0.00045 20.5 0.1 0.00065 19.9 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 CAR21833.1 - 0.008 16.0 0.3 0.012 15.4 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.13 CAR21833.1 - 0.019 14.9 0.3 0.033 14.1 0.2 1.6 1 1 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 CAR21833.1 - 0.062 12.2 0.2 0.086 11.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase PGK PF00162.14 CAR21833.1 - 0.087 11.3 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase adh_short PF00106.20 CAR21833.1 - 0.12 12.3 0.5 3.1 7.6 0.4 2.2 1 1 0 1 1 1 0 short chain dehydrogenase Ydc2-catalyt PF09159.5 CAR21834.1 - 3.2e-45 154.7 0.0 5.8e-45 153.9 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 CAR21834.1 - 0.071 12.9 0.0 13 5.6 0.0 2.7 2 1 0 2 2 2 0 Poxvirus A22 protein DUF1092 PF06485.6 CAR21835.1 - 0.11 11.4 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) zf-TRM13_CCCH PF11722.3 CAR21835.1 - 0.48 9.8 3.9 4.2 6.8 0.7 2.8 2 1 0 2 2 2 0 CCCH zinc finger in TRM13 protein Flavoprotein PF02441.14 CAR21836.1 - 6.5e-43 145.4 0.0 1e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein CDC45 PF02724.9 CAR21836.1 - 1.2 7.0 12.3 1.8 6.5 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 CAR21836.1 - 1.3 6.7 18.9 1.7 6.2 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi NAD_binding_6 PF08030.7 CAR21837.1 - 3.4e-20 72.5 0.0 6e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CAR21837.1 - 5.6e-20 71.6 11.1 5.6e-20 71.6 7.7 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAR21837.1 - 6.3e-20 71.0 0.0 1.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain CFEM PF05730.6 CAR21837.1 - 0.087 12.6 0.5 0.24 11.2 0.4 1.8 1 0 0 1 1 1 0 CFEM domain zf-Tim10_DDP PF02953.10 CAR21838.1 - 1.4e-24 85.1 3.4 1.7e-24 84.9 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CAR21838.1 - 0.016 14.6 2.2 0.022 14.1 1.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Cyto_heme_lyase PF01265.12 CAR21839.1 - 2.9e-86 289.2 0.8 3.2e-86 289.1 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase G-alpha PF00503.15 CAR21840.1 - 2.1e-120 402.0 0.7 2.3e-120 401.8 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CAR21840.1 - 7.9e-16 57.7 1.3 4.6e-10 39.0 0.0 2.8 2 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR21840.1 - 0.00017 20.8 0.3 0.027 13.5 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR21840.1 - 0.00071 20.0 0.0 0.79 10.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein ATP_bind_1 PF03029.12 CAR21840.1 - 0.047 13.2 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CAR21840.1 - 0.057 13.3 0.0 11 5.9 0.0 2.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CAR21840.1 - 0.089 12.3 0.1 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ParBc PF02195.13 CAR21841.1 - 9.6e-13 48.0 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain DUF3560 PF12083.3 CAR21842.1 - 0.04 13.9 0.2 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Ldh_1_C PF02866.13 CAR21843.1 - 4.4e-51 173.0 0.1 7e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CAR21843.1 - 6.5e-44 149.1 0.2 9.4e-44 148.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CAR21843.1 - 8.6e-06 24.6 0.0 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CAR21843.1 - 0.05 13.6 0.9 0.17 11.9 0.6 1.8 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_4 PF02056.11 CAR21843.1 - 0.13 11.5 0.9 4.8 6.4 0.2 2.5 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase zf-CHY PF05495.7 CAR21844.1 - 7.7e-16 58.0 10.6 1e-15 57.6 7.3 1.1 1 0 0 1 1 1 1 CHY zinc finger ADK_lid PF05191.9 CAR21844.1 - 0.13 11.9 3.9 3.6 7.3 0.1 3.3 3 1 0 3 3 3 0 Adenylate kinase, active site lid Cytochrome_C7 PF14522.1 CAR21844.1 - 0.34 10.5 6.3 0.55 9.9 4.3 1.3 1 0 0 1 1 1 0 Cytochrome c7 DZR PF12773.2 CAR21844.1 - 0.66 9.8 9.4 37 4.2 6.6 2.6 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 CAR21844.1 - 1.1 9.0 5.7 1.7 8.3 3.7 1.5 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ank_4 PF13637.1 CAR21845.1 - 6e-21 74.4 3.5 5.3e-09 36.3 0.1 3.5 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR21845.1 - 9.1e-19 67.6 1.6 7.8e-09 35.7 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CAR21845.1 - 1.1e-15 56.5 17.3 9.8e-05 21.9 0.1 5.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 CAR21845.1 - 7.3e-10 38.1 12.3 0.022 14.9 0.2 5.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 CAR21845.1 - 6.7e-09 35.7 3.5 0.004 17.3 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 CAR21846.1 - 1.5e-27 96.9 0.0 2.2e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR21846.1 - 1.3e-20 73.9 0.0 5.4e-20 71.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR21846.1 - 5.4e-09 35.9 0.0 1.2e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.9 CAR21846.1 - 6.2e-07 28.1 0.0 2.2e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Ndr family Esterase PF00756.15 CAR21846.1 - 0.00016 21.1 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.8 CAR21846.1 - 0.00054 19.5 0.0 0.0009 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.8 CAR21846.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CAR21846.1 - 0.0019 17.8 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 CAR21846.1 - 0.0022 17.4 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) BAAT_C PF08840.6 CAR21846.1 - 0.041 13.5 0.0 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 CAR21846.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 CAR21846.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein TUG-UBL1 PF11470.3 CAR21847.1 - 2.5e-16 59.3 0.1 6.6e-16 57.9 0.1 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 CAR21847.1 - 1.3e-12 47.5 0.0 3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain SURF6 PF04935.7 CAR21849.1 - 4.6e-49 166.5 48.1 4.6e-49 166.5 33.4 3.1 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 CAR21849.1 - 1.5e-19 69.7 4.8 1.5e-19 69.7 3.3 6.2 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 Lentiviral_Tat PF02998.9 CAR21849.1 - 0.31 10.8 5.4 1.1 9.1 3.7 1.9 1 0 0 1 1 1 0 Lentiviral Tat protein EF1G PF00647.14 CAR21850.1 - 4.9e-44 148.4 0.0 2.2e-43 146.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CAR21850.1 - 3.9e-11 42.7 0.1 3.9e-11 42.7 0.1 2.4 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CAR21850.1 - 1.8e-10 40.8 0.1 5.7e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAR21850.1 - 2.8e-08 33.5 0.4 6.1e-08 32.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CAR21850.1 - 3.8e-05 23.8 0.0 7.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain V-ATPase_C PF03223.10 CAR21851.1 - 5e-126 420.5 0.4 5.7e-126 420.3 0.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Med15 PF09606.5 CAR21853.1 - 0.11 10.6 24.4 0.14 10.3 16.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SlyX PF04102.7 CAR21854.1 - 1.4 9.2 8.1 1.5 9.2 4.2 2.2 1 1 1 2 2 2 0 SlyX Lge1 PF11488.3 CAR21854.1 - 2.5 8.3 10.3 9.1 6.5 7.0 2.1 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF3597 PF12200.3 CAR21854.1 - 3.7 7.9 8.8 12 6.3 2.8 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3597) Kelch_3 PF13415.1 CAR21855.1 - 1.2e-35 120.8 10.0 4.5e-07 29.8 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CAR21855.1 - 1.9e-29 101.1 12.5 9.9e-05 22.2 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CAR21855.1 - 9.5e-23 79.3 11.3 8.5e-05 22.5 0.1 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.1 CAR21855.1 - 1.9e-21 75.5 22.3 1.9e-05 24.3 0.1 7.2 6 2 1 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 CAR21855.1 - 3.1e-20 71.4 1.9 6.2e-07 28.8 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CAR21855.1 - 2e-12 46.3 11.0 0.1 12.3 0.0 6.8 6 1 0 6 6 6 4 Kelch motif Syntaxin-6_N PF09177.6 CAR21855.1 - 0.00023 21.5 6.3 0.00023 21.5 4.4 3.7 4 0 0 4 4 4 1 Syntaxin 6, N-terminal Cep57_CLD_2 PF14197.1 CAR21855.1 - 0.0014 18.4 3.3 0.0014 18.4 2.3 4.0 4 1 1 5 5 5 1 Centrosome localisation domain of PPC89 DUF904 PF06005.7 CAR21855.1 - 0.0078 16.4 1.0 0.0078 16.4 0.7 5.0 4 1 0 4 4 4 1 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 CAR21855.1 - 2.2 8.0 38.9 0.081 12.6 12.8 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ApoO PF09769.4 CAR21859.1 - 1.1e-37 129.1 0.0 1.7e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O BRCT PF00533.21 CAR21860.1 - 1.2e-18 66.9 0.5 6.6e-05 22.9 0.0 4.6 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CAR21860.1 - 1.2e-17 63.5 2.2 1.9e-13 50.0 0.1 3.5 3 0 0 3 3 3 2 twin BRCT domain DUF1364 PF07102.7 CAR21860.1 - 0.049 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Ank_2 PF12796.2 CAR21861.1 - 4.2e-29 100.7 0.0 9e-15 54.7 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.14 CAR21861.1 - 4.5e-29 102.0 9.3 1.5e-14 54.4 3.2 2.8 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 CAR21861.1 - 3.9e-26 89.5 0.6 2e-06 27.2 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 CAR21861.1 - 2.1e-22 79.0 2.3 3.5e-06 27.3 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAR21861.1 - 2.5e-21 75.2 1.0 3.9e-05 23.7 0.0 5.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR21861.1 - 3.6e-20 70.0 1.9 9.2e-06 25.4 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat GDPD PF03009.12 CAR21861.1 - 2.2e-05 24.0 0.0 0.00011 21.8 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 CAR21862.1 - 4.1e-49 164.8 1.8 3.3e-16 59.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CAR21862.1 - 3e-34 115.1 0.0 7.9e-07 28.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 CAR21862.1 - 5.1e-31 106.4 6.5 1.1e-08 35.3 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR21862.1 - 2.7e-27 92.0 0.0 0.00039 20.3 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CAR21862.1 - 3.2e-26 90.7 0.1 8.1e-09 35.4 0.2 6.0 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Band_7 PF01145.20 CAR21863.1 - 8.1e-22 77.9 1.7 8.1e-22 77.9 1.2 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 CAR21863.1 - 0.015 14.5 0.9 0.023 14.0 0.6 1.2 1 0 0 1 1 1 0 MraW methylase family Spo12 PF05032.7 CAR21864.1 - 7.4e-20 70.2 4.7 7.4e-20 70.2 3.3 1.6 2 0 0 2 2 2 1 Spo12 family SMI1_KNR4 PF09346.5 CAR21867.1 - 5.3e-35 120.2 0.0 2.8e-34 117.9 0.0 2.2 1 1 1 2 2 2 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.1 CAR21867.1 - 0.085 13.3 0.0 7.5 7.0 0.0 2.7 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall DIE2_ALG10 PF04922.7 CAR21868.1 - 7.6e-118 393.8 38.1 9.4e-118 393.5 26.4 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Lectin_C PF00059.16 CAR21869.1 - 0.053 14.1 5.3 0.11 13.1 2.3 2.4 2 0 0 2 2 2 0 Lectin C-type domain Pex24p PF06398.6 CAR21870.1 - 2.5e-73 246.9 0.1 3.4e-73 246.4 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.5 CAR21870.1 - 0.015 14.8 0.8 0.03 13.8 0.2 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.7 CAR21870.1 - 0.026 12.7 0.1 0.041 12.0 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Reticulon PF02453.12 CAR21870.1 - 0.1 12.1 0.1 1 8.9 0.0 2.2 1 1 0 2 2 2 0 Reticulon WD40 PF00400.27 CAR21871.1 - 1.4e-13 50.1 9.3 0.0018 18.1 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat WD40 PF00400.27 CAR21872.1 - 1e-06 28.4 0.0 0.0013 18.5 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CAR21872.1 - 0.0048 15.7 0.3 0.019 13.8 0.0 2.0 3 0 0 3 3 3 1 Coatomer WD associated region SKG6 PF08693.5 CAR21874.1 - 1.4e-11 43.4 6.9 2.4e-11 42.7 4.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 CAR21874.1 - 0.00047 19.7 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 CAR21874.1 - 0.0098 15.6 0.1 0.037 13.7 0.0 2.1 2 0 0 2 2 2 1 TMEM154 protein family DUF3377 PF11857.3 CAR21874.1 - 0.014 15.0 0.1 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) P12 PF12669.2 CAR21874.1 - 0.2 11.8 2.0 2.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family Ribosomal_S4 PF00163.14 CAR21875.1 - 1.3e-23 83.1 1.7 3e-23 82.0 1.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CAR21875.1 - 7.4e-12 44.5 0.0 2.1e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_L6 PF00347.18 CAR21876.1 - 2.8e-26 91.7 0.2 3.1e-12 46.8 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L3 PF00297.17 CAR21877.1 - 5.7e-44 150.4 1.7 1.1e-42 146.2 1.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 CRM1_C PF08767.6 CAR21878.1 - 4.7e-129 429.8 2.3 4.7e-129 429.8 1.6 2.7 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CAR21878.1 - 3e-38 131.0 9.5 1.3e-37 129.0 4.9 3.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 CAR21878.1 - 5.2e-14 51.9 0.8 1.5e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Ion_trans PF00520.26 CAR21879.1 - 6.7e-88 293.1 94.1 1e-31 109.7 9.5 6.0 6 1 0 6 6 6 4 Ion transport protein Gpi1 PF05024.10 CAR21880.1 - 2.3e-51 174.1 15.1 2.3e-51 174.1 10.4 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) MRP-S33 PF08293.6 CAR21881.1 - 2.3e-29 101.2 0.9 2.7e-29 100.9 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF4023 PF13215.1 CAR21881.1 - 0.44 10.3 5.0 0.13 12.0 1.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4023) Ribosomal_S2 PF00318.15 CAR21882.1 - 2.6e-39 134.6 0.0 1.7e-20 73.1 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S2 Ferric_reduct PF01794.14 CAR21883.1 - 4.3e-18 65.6 17.0 4.3e-18 65.6 11.8 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAR21883.1 - 0.00093 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CAR21883.1 - 0.04 13.8 0.0 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 Ferric reductase NAD binding domain LicD PF04991.8 CAR21884.1 - 1.1e-22 81.1 0.1 1.1e-22 81.1 0.1 2.1 2 0 0 2 2 2 1 LicD family AATase PF07247.7 CAR21885.1 - 2.7e-54 184.4 0.0 5.7e-54 183.4 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CAR21885.1 - 2.2e-07 30.0 0.0 0.00075 18.4 0.0 2.1 2 0 0 2 2 2 2 Condensation domain zf-ZPR1 PF03367.8 CAR21886.1 - 1.4e-116 385.1 2.8 8.8e-59 197.2 0.1 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain UPF0547 PF10571.4 CAR21886.1 - 0.13 12.0 5.3 9.7 5.9 0.1 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Lar_restr_allev PF14354.1 CAR21886.1 - 0.2 11.9 6.9 2.7 8.3 0.8 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar Elf1 PF05129.8 CAR21886.1 - 0.33 10.6 5.0 4.6 6.9 0.1 2.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HSA PF07529.8 CAR21887.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 HSA DUF1237 PF06824.6 CAR21888.1 - 7.2e-173 575.0 0.0 8.5e-173 574.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DUF106 PF01956.11 CAR21889.1 - 1.3e-52 177.7 1.1 1.5e-52 177.4 0.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 ATP_bind_1 PF03029.12 CAR21890.1 - 6.5e-84 281.1 0.1 1.1e-83 280.4 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 CAR21890.1 - 2.9e-07 30.0 0.2 9.7e-07 28.3 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 CAR21890.1 - 3.2e-07 29.9 2.7 1.1e-06 28.2 0.1 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CAR21890.1 - 0.0001 22.4 0.0 0.00048 20.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CAR21890.1 - 0.00014 22.6 2.1 0.00077 20.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR21890.1 - 0.00018 21.4 0.0 0.00051 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CAR21890.1 - 0.00043 20.2 0.0 0.0023 17.8 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR21890.1 - 0.00044 19.5 0.0 0.012 14.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.4 CAR21890.1 - 0.00097 18.6 0.0 0.03 13.8 0.0 2.6 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CAR21890.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 CAR21890.1 - 0.0013 18.3 0.0 0.0044 16.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 CAR21890.1 - 0.0022 17.5 2.1 0.018 14.5 1.4 2.2 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.12 CAR21890.1 - 0.0045 16.8 0.4 3.6 7.3 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 CAR21890.1 - 0.0063 16.8 3.5 0.0081 16.4 0.0 2.7 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.17 CAR21890.1 - 0.0064 15.9 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Glyco_tranf_2_3 PF13641.1 CAR21890.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase like family 2 AAA_16 PF13191.1 CAR21890.1 - 0.013 15.5 0.1 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 CAR21890.1 - 0.014 14.7 0.1 0.29 10.5 0.1 2.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CAR21890.1 - 0.015 14.1 0.0 3 6.5 0.0 2.4 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 CAR21890.1 - 0.016 14.9 0.2 0.049 13.3 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 CAR21890.1 - 0.018 14.2 0.1 0.54 9.4 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CAR21890.1 - 0.025 13.7 0.0 0.42 9.7 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Thymidylate_kin PF02223.12 CAR21890.1 - 0.026 13.8 1.5 0.87 8.9 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase PRK PF00485.13 CAR21890.1 - 0.03 13.9 0.4 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 CAR21890.1 - 0.034 13.7 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CAR21890.1 - 0.058 13.8 3.3 1.1 9.7 0.1 3.1 2 1 0 2 2 2 0 Miro-like protein Arf PF00025.16 CAR21890.1 - 0.072 12.3 0.0 2.2 7.5 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family UPF0079 PF02367.12 CAR21890.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2458 PF10454.4 CAR21890.1 - 0.26 11.1 6.0 0.56 10.0 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) ATP-synt_E PF05680.7 CAR21890.1 - 0.63 10.0 6.0 1.6 8.7 4.2 1.7 1 0 0 1 1 1 0 ATP synthase E chain FadA PF09403.5 CAR21890.1 - 0.67 9.9 10.3 7.4 6.5 7.1 2.4 1 1 0 1 1 1 0 Adhesion protein FadA PAC2 PF09754.4 CAR21891.1 - 2e-28 99.7 0.0 2.7e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 PAC2 family DUF2066 PF09839.4 CAR21891.1 - 0.033 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) HEAT_2 PF13646.1 CAR21892.1 - 1.5e-36 124.5 0.0 3.3e-16 59.3 0.0 3.1 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 CAR21892.1 - 4.9e-17 60.6 0.2 0.00074 19.7 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.17 CAR21892.1 - 4.5e-12 44.9 0.4 0.026 14.5 0.1 5.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 CAR21892.1 - 3.2e-09 37.0 2.3 0.001 19.4 0.1 4.8 2 2 3 5 5 5 4 HEAT-like repeat Arm PF00514.18 CAR21892.1 - 1.1e-06 28.2 0.2 0.017 14.9 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Ham1p_like PF01725.11 CAR21893.1 - 2.8e-51 173.5 0.0 3.2e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Xpo1 PF08389.7 CAR21894.1 - 3.4e-37 127.6 0.7 3.4e-37 127.6 0.5 3.6 4 1 0 4 4 4 1 Exportin 1-like protein AAA PF00004.24 CAR21896.1 - 6.2e-16 58.7 0.0 2.7e-15 56.7 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CAR21896.1 - 1.2e-14 54.3 0.0 1.2e-13 51.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CAR21896.1 - 3.6e-14 52.4 0.3 7.8e-14 51.4 0.0 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CAR21896.1 - 7.9e-11 41.3 0.2 3.1e-08 32.7 0.0 2.5 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CAR21896.1 - 3.4e-07 30.4 0.1 2.2e-05 24.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR21896.1 - 1.2e-06 27.7 0.0 2.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAR21896.1 - 6.7e-06 26.2 0.1 0.001 19.0 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 CAR21896.1 - 8.8e-06 25.4 0.0 1.2e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAR21896.1 - 1.4e-05 25.0 0.0 3.7e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR21896.1 - 6.2e-05 22.6 0.0 0.0002 21.0 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CAR21896.1 - 7.8e-05 22.3 0.0 0.0028 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CAR21896.1 - 0.0002 20.5 0.0 0.0051 16.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 CAR21896.1 - 0.00043 19.8 0.0 0.00091 18.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 CAR21896.1 - 0.0026 18.5 0.0 0.026 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CAR21896.1 - 0.0028 16.6 0.0 0.0056 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) SNF2_N PF00176.18 CAR21896.1 - 0.0029 16.4 0.0 0.18 10.5 0.0 2.2 1 1 0 2 2 2 1 SNF2 family N-terminal domain AAA_24 PF13479.1 CAR21896.1 - 0.0038 16.8 0.7 0.0094 15.5 0.5 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CAR21896.1 - 0.0056 16.5 0.0 0.031 14.0 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CAR21896.1 - 0.0074 16.0 0.0 0.91 9.1 0.0 2.4 1 1 1 2 2 2 1 Archaeal ATPase DUF2075 PF09848.4 CAR21896.1 - 0.0089 15.0 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CAR21896.1 - 0.011 15.4 0.0 0.043 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CAR21896.1 - 0.033 12.9 0.1 0.35 9.5 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus AAA_23 PF13476.1 CAR21896.1 - 0.041 14.2 0.0 0.072 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CAR21896.1 - 0.041 13.3 0.1 1.2 8.4 0.0 2.5 1 1 1 2 2 2 0 AAA-like domain AAA_18 PF13238.1 CAR21896.1 - 0.059 13.6 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CAR21896.1 - 0.06 12.8 0.1 0.26 10.7 0.0 1.8 1 1 1 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 CAR21896.1 - 0.086 13.0 0.1 0.43 10.7 0.0 2.2 2 1 1 3 3 3 0 RNA helicase AAA_25 PF13481.1 CAR21896.1 - 0.089 12.1 0.2 0.31 10.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CAR21896.1 - 0.096 12.2 0.2 1.3 8.6 0.0 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CAR21896.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Yae1_N PF09811.4 CAR21897.1 - 6.1e-12 44.8 0.9 9.9e-12 44.1 0.6 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FAT PF02259.18 CAR21898.1 - 1.4e-134 448.6 0.8 3.2e-134 447.3 0.0 2.1 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 CAR21898.1 - 1.8e-64 216.4 0.4 1.8e-64 216.4 0.3 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 CAR21898.1 - 3.8e-61 206.5 0.2 8e-61 205.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 CAR21898.1 - 1.3e-41 140.7 0.4 1.3e-41 140.7 0.3 3.0 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 CAR21898.1 - 3.6e-17 61.4 0.2 8.9e-17 60.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 CAR21898.1 - 7.3e-13 48.6 11.0 0.13 12.5 0.1 9.0 6 2 3 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 CAR21898.1 - 3.1e-07 30.6 7.3 0.00053 20.3 0.0 7.5 8 0 0 8 8 8 1 HEAT-like repeat HEAT PF02985.17 CAR21898.1 - 1.3e-06 27.9 8.7 0.1 12.7 0.0 7.8 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.2 CAR21898.1 - 0.0061 16.9 4.9 7.6 6.9 0.0 5.0 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region TPR_16 PF13432.1 CAR21898.1 - 0.088 13.5 0.1 82 4.0 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Actin PF00022.14 CAR21899.1 - 6.6e-93 311.2 0.0 1.3e-92 310.2 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR21899.1 - 0.00031 19.4 0.0 0.11 11.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Cpn60_TCP1 PF00118.19 CAR21900.1 - 2.6e-142 474.8 3.6 3.1e-142 474.6 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIIS_C PF01096.13 CAR21901.1 - 1.1e-18 66.5 8.9 1.1e-18 66.4 1.1 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CAR21901.1 - 8.5e-12 44.5 9.2 5.1e-10 38.8 0.3 3.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.1 CAR21901.1 - 4.6e-06 25.6 9.1 1.6 8.0 0.1 4.3 4 0 0 4 4 4 3 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CAR21901.1 - 6.5e-06 25.4 10.2 0.031 13.7 0.8 4.0 3 1 0 3 3 3 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CAR21901.1 - 2.5e-05 23.9 3.4 0.016 14.9 0.7 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DZR PF12773.2 CAR21901.1 - 8.7e-05 22.2 8.2 0.011 15.5 0.3 2.9 2 1 0 2 2 2 2 Double zinc ribbon Lar_restr_allev PF14354.1 CAR21901.1 - 0.00033 20.8 8.8 0.0018 18.5 0.3 2.7 2 1 0 2 2 2 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 CAR21901.1 - 0.00081 18.6 10.4 0.08 12.2 2.1 3.2 3 1 0 3 3 3 2 TFIIB zinc-binding Mu-like_Com PF10122.4 CAR21901.1 - 0.006 15.6 0.6 0.39 9.8 0.1 2.5 2 0 0 2 2 2 1 Mu-like prophage protein Com OrfB_Zn_ribbon PF07282.6 CAR21901.1 - 0.012 15.2 8.0 0.095 12.3 0.2 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 CAR21901.1 - 0.014 15.2 12.1 2.4 8.2 0.7 3.7 3 1 0 3 3 3 0 Zinc ribbon domain SprT-like PF10263.4 CAR21901.1 - 0.023 14.3 0.9 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 SprT-like family C1_1 PF00130.17 CAR21901.1 - 0.029 14.0 3.5 0.58 9.9 0.1 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2387 PF09526.5 CAR21901.1 - 0.032 14.1 5.9 0.079 12.8 0.2 2.7 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) RRN7 PF11781.3 CAR21901.1 - 0.037 13.5 14.1 15 5.1 0.0 4.2 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-TFIIB PF13453.1 CAR21901.1 - 0.042 13.0 5.6 0.11 11.6 0.7 2.7 2 1 0 2 2 2 0 Transcription factor zinc-finger YhfH PF14149.1 CAR21901.1 - 0.046 13.5 9.8 9.9 6.0 0.2 4.1 4 0 0 4 4 4 0 YhfH-like protein Terminase_GpA PF05876.7 CAR21901.1 - 0.048 12.0 3.2 0.086 11.1 0.4 2.0 1 1 1 3 3 3 0 Phage terminase large subunit (GpA) Rubredoxin PF00301.15 CAR21901.1 - 0.048 13.5 6.8 10 6.0 0.1 3.6 4 0 0 4 4 3 0 Rubredoxin DUF2072 PF09845.4 CAR21901.1 - 0.051 13.5 6.5 0.39 10.6 0.0 3.0 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) GATA PF00320.22 CAR21901.1 - 0.051 12.9 9.4 0.19 11.1 1.0 3.0 3 0 0 3 3 3 0 GATA zinc finger zf-ISL3 PF14690.1 CAR21901.1 - 0.056 13.4 3.8 1.2 9.1 0.2 3.5 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_5 PF13719.1 CAR21901.1 - 0.059 12.9 7.2 11 5.7 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.8 CAR21901.1 - 0.059 13.0 6.8 0.21 11.2 0.3 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 CAR21901.1 - 0.076 12.7 7.7 11 5.8 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.16 CAR21901.1 - 0.078 12.8 6.5 3.3 7.6 1.1 2.8 2 1 0 2 2 2 0 IBR domain zf-C4_Topoisom PF01396.14 CAR21901.1 - 0.098 12.1 10.1 0.055 12.9 1.1 3.6 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-AN1 PF01428.11 CAR21901.1 - 0.11 12.4 5.2 12 5.8 0.1 3.5 3 1 0 3 3 3 0 AN1-like Zinc finger Ogr_Delta PF04606.7 CAR21901.1 - 0.12 12.0 10.0 0.059 13.0 1.8 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.1 CAR21901.1 - 0.13 12.5 8.5 6.3 7.1 0.1 3.5 4 1 0 4 4 3 0 Recombinase zinc beta ribbon domain zf-C3HC4_4 PF15227.1 CAR21901.1 - 0.16 11.8 3.2 1.3 8.9 0.1 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING RIG-I_C-RD PF11648.3 CAR21901.1 - 0.17 11.7 2.7 0.14 12.0 0.3 2.0 2 1 0 2 2 2 0 C-terminal domain of RIG-I HypA PF01155.14 CAR21901.1 - 0.26 10.9 9.3 1.1 8.9 1.9 3.0 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family Nudix_N_2 PF14803.1 CAR21901.1 - 0.26 10.9 13.8 8.5 6.1 0.0 4.2 3 1 1 4 4 4 0 Nudix N-terminal zf-RING_5 PF14634.1 CAR21901.1 - 0.27 10.9 5.9 2.4 7.9 0.5 3.0 3 0 0 3 3 3 0 zinc-RING finger domain zf-MYND PF01753.13 CAR21901.1 - 0.27 11.1 5.2 2.7 7.9 0.8 2.5 2 1 0 2 2 2 0 MYND finger Prok-RING_1 PF14446.1 CAR21901.1 - 0.34 10.6 7.1 4.9 6.9 0.7 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-H2C2_2 PF13465.1 CAR21901.1 - 0.36 11.2 8.3 0.39 11.0 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger double domain zf-C2H2_3 PF13878.1 CAR21901.1 - 0.88 9.1 11.1 2.2 7.8 0.0 4.0 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-DNA_Pol PF08996.5 CAR21901.1 - 0.96 8.7 5.0 0.69 9.2 0.4 2.2 1 1 2 3 3 3 0 DNA Polymerase alpha zinc finger zf-HYPF PF07503.7 CAR21901.1 - 1.2 8.5 11.8 2.1 7.8 0.1 3.9 4 0 0 4 4 4 0 HypF finger PolC_DP2 PF03833.8 CAR21901.1 - 1.5 6.3 3.9 0.74 7.3 0.5 1.8 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 NOB1_Zn_bind PF08772.6 CAR21901.1 - 1.9 8.3 9.2 7.5 6.4 0.8 3.4 3 2 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like UPF0547 PF10571.4 CAR21901.1 - 1.9 8.2 16.0 17 5.2 0.1 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 PHD PF00628.24 CAR21901.1 - 2.1 8.1 8.6 5.3 6.8 0.3 2.8 2 1 1 3 3 3 0 PHD-finger zf-C2HC5 PF06221.8 CAR21901.1 - 2.2 8.1 9.3 1.5 8.6 0.2 3.1 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type CpXC PF14353.1 CAR21901.1 - 3.1 7.7 10.0 3.6 7.5 0.1 3.3 2 1 1 4 4 3 0 CpXC protein zf-IS66 PF13005.2 CAR21901.1 - 3.6 7.6 10.1 21 5.1 0.1 3.9 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 zf-NADH-PPase PF09297.6 CAR21901.1 - 3.7 7.1 13.4 17 5.0 0.1 4.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Baculo_LEF5_C PF11792.3 CAR21901.1 - 3.8 6.9 9.5 0.085 12.2 0.6 2.7 3 1 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-tcix PF14952.1 CAR21901.1 - 4.1 6.8 11.1 7 6.0 0.2 3.9 4 0 0 4 4 4 0 Putative treble-clef, zinc-finger, Zn-binding zf-CHY PF05495.7 CAR21901.1 - 4.1 7.6 8.3 4.4 7.5 0.1 2.8 2 1 0 2 2 2 0 CHY zinc finger zf-dskA_traR PF01258.12 CAR21901.1 - 4.2 7.1 10.6 15 5.4 0.1 3.7 4 0 0 4 4 3 0 Prokaryotic dksA/traR C4-type zinc finger Nop10p PF04135.7 CAR21901.1 - 4.8 6.9 5.3 1.4 8.6 0.1 2.7 4 0 0 4 4 2 0 Nucleolar RNA-binding protein, Nop10p family DNA_RNApol_7kD PF03604.8 CAR21901.1 - 5.1 6.6 16.6 10 5.6 0.7 4.0 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S27e PF01667.12 CAR21901.1 - 5.7 6.5 10.2 16 5.1 0.0 3.7 2 2 1 3 3 3 0 Ribosomal protein S27 zf-C2H2_4 PF13894.1 CAR21901.1 - 6.6 7.3 7.3 23 5.6 1.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS91 PF14319.1 CAR21901.1 - 7.6 6.0 9.4 7.6 6.0 1.3 3.0 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-Mss51 PF13824.1 CAR21901.1 - 7.7 6.4 10.2 7.2 6.5 1.4 3.0 2 2 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 CAR21901.1 - 7.7 6.2 11.6 20 4.9 0.4 3.9 4 0 0 4 4 4 0 HIT zinc finger PhnA_Zn_Ribbon PF08274.7 CAR21901.1 - 8.5 6.2 12.3 25 4.7 0.1 3.5 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zf-C2H2 PF00096.21 CAR21901.1 - 9.9 6.7 12.5 1.5 9.2 1.1 3.7 4 0 0 4 4 3 0 Zinc finger, C2H2 type LicD PF04991.8 CAR21902.1 - 2.3e-48 165.0 4.4 4.6e-48 164.0 3.0 1.5 1 0 0 1 1 1 1 LicD family DUF3050 PF11251.3 CAR21902.1 - 0.045 12.9 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) DUF1825 PF08855.5 CAR21902.1 - 0.088 12.8 0.2 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) CN_hydrolase PF00795.17 CAR21903.1 - 4e-18 65.4 0.0 5.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LicD PF04991.8 CAR21904.1 - 2.2e-51 174.8 1.2 2.2e-51 174.8 0.8 2.1 2 0 0 2 2 2 1 LicD family HLH PF00010.21 CAR21905.1 - 1.3e-12 47.1 3.9 3.6e-12 45.7 2.7 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2344 PF10105.4 CAR21905.1 - 0.035 13.5 1.7 0.057 12.9 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Pkinase PF00069.20 CAR21906.1 - 8.7e-43 146.3 0.0 1.6e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR21906.1 - 5.4e-21 74.8 0.0 9e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR21906.1 - 1.5e-05 24.1 0.0 4.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR21906.1 - 0.0011 18.8 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR21906.1 - 0.0012 17.9 0.1 0.0037 16.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAR21906.1 - 0.047 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family AAA PF00004.24 CAR21907.1 - 1.5e-55 186.9 0.0 3.1e-44 150.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CAR21907.1 - 1e-24 86.3 0.3 2.4e-24 85.1 0.2 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CAR21907.1 - 1.8e-13 50.8 0.2 1.4e-06 28.3 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 CAR21907.1 - 5.2e-10 40.1 0.0 0.0026 18.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CAR21907.1 - 3.8e-09 36.7 0.8 0.00043 20.4 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CAR21907.1 - 4.2e-09 36.3 0.0 0.0041 17.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 CAR21907.1 - 8.3e-08 32.3 0.0 0.0029 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CAR21907.1 - 1.4e-07 31.1 0.0 0.0024 17.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 CAR21907.1 - 3e-07 30.2 0.2 0.018 14.7 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.1 CAR21907.1 - 1.2e-06 28.8 0.2 0.022 15.0 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CAR21907.1 - 3.3e-06 26.6 0.5 0.5 9.7 0.1 3.9 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.1 CAR21907.1 - 1e-05 25.4 0.0 0.024 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CAR21907.1 - 2e-05 24.4 0.1 0.051 13.2 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 CAR21907.1 - 2.3e-05 24.5 0.1 0.47 10.6 0.0 3.5 3 0 0 3 3 3 2 RNA helicase AAA_5 PF07728.9 CAR21907.1 - 2.4e-05 24.0 0.1 0.24 11.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CAR21907.1 - 9e-05 22.4 0.0 0.47 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 CAR21907.1 - 0.00012 21.6 0.0 0.071 12.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 CAR21907.1 - 0.00031 20.2 0.1 0.27 10.6 0.0 3.2 3 1 1 4 4 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 CAR21907.1 - 0.00038 19.5 0.1 0.037 13.1 0.0 3.1 4 0 0 4 4 4 1 Zeta toxin RuvB_N PF05496.7 CAR21907.1 - 0.00045 19.3 0.0 0.003 16.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CAR21907.1 - 0.00048 19.3 0.1 0.13 11.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 CAR21907.1 - 0.0016 18.2 1.2 0.47 10.1 0.1 3.3 3 0 0 3 3 3 1 NTPase AAA_3 PF07726.6 CAR21907.1 - 0.0024 17.4 0.0 0.3 10.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CAR21907.1 - 0.0025 18.1 0.2 2.4 8.4 0.1 3.2 2 1 0 2 2 2 1 ABC transporter DUF815 PF05673.8 CAR21907.1 - 0.0026 16.7 0.2 1.8 7.4 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) SKI PF01202.17 CAR21907.1 - 0.0032 17.3 0.1 0.26 11.1 0.0 2.7 3 0 0 3 3 2 1 Shikimate kinase AAA_19 PF13245.1 CAR21907.1 - 0.0039 16.8 0.5 4.2 7.2 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain Bac_DnaA PF00308.13 CAR21907.1 - 0.0048 16.5 0.0 0.48 10.0 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein KaiC PF06745.8 CAR21907.1 - 0.0067 15.5 0.0 3.2 6.8 0.0 2.5 2 0 0 2 2 2 1 KaiC KAP_NTPase PF07693.9 CAR21907.1 - 0.0073 15.3 0.0 0.096 11.6 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain UPF0079 PF02367.12 CAR21907.1 - 0.0083 15.7 0.0 4 7.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 CAR21907.1 - 0.011 14.6 0.0 1.7 7.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 CAR21907.1 - 0.011 15.3 1.3 2.2 7.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.5 CAR21907.1 - 0.011 15.6 0.1 0.037 13.9 0.0 1.9 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 CAR21907.1 - 0.011 14.4 0.1 0.034 12.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus DUF258 PF03193.11 CAR21907.1 - 0.011 14.8 0.0 0.046 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 CAR21907.1 - 0.013 15.0 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 CAR21907.1 - 0.016 14.3 0.2 0.79 8.8 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 CAR21907.1 - 0.019 14.4 0.1 0.29 10.6 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2075 PF09848.4 CAR21907.1 - 0.02 13.8 0.3 3.8 6.3 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 CAR21907.1 - 0.041 13.5 0.3 0.18 11.4 0.2 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CAR21907.1 - 0.058 12.8 0.7 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CAR21907.1 - 0.064 12.1 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.15 CAR21907.1 - 0.1 12.2 0.1 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Cytidylate_kin2 PF13189.1 CAR21907.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family Clat_adaptor_s PF01217.15 CAR21908.1 - 2.5e-50 169.8 1.0 2.8e-50 169.7 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain WH1 PF00568.18 CAR21908.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 WH1 domain Thymidylate_kin PF02223.12 CAR21909.1 - 7e-39 133.1 0.0 8.1e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 CAR21909.1 - 0.033 14.5 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCR_alpha PF02249.12 CAR21909.1 - 0.13 12.3 0.1 0.5 10.3 0.1 1.8 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain UPF0160 PF03690.8 CAR21910.1 - 0.14 11.5 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) DUF4588 PF15251.1 CAR21911.1 - 1.7e-08 34.7 1.2 2.7e-08 34.0 0.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Hairy_orange PF07527.8 CAR21911.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Hairy Orange FUSC PF04632.7 CAR21911.1 - 0.41 9.0 3.1 0.56 8.5 2.2 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family SUR7 PF06687.7 CAR21912.1 - 1.1e-38 132.8 14.2 1.3e-38 132.6 9.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 CAR21912.1 - 0.11 12.3 6.1 0.084 12.7 3.2 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Pox_I5 PF04713.7 CAR21912.1 - 0.49 10.1 3.5 4.1 7.1 0.2 2.6 3 0 0 3 3 3 0 Poxvirus protein I5 GFO_IDH_MocA PF01408.17 CAR21913.1 - 7.2e-05 23.3 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-HIT PF04438.11 CAR21914.1 - 8.9e-12 44.4 12.4 1.6e-11 43.6 8.6 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF2089 PF09862.4 CAR21914.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) zf-MYND PF01753.13 CAR21914.1 - 0.014 15.2 10.9 0.025 14.4 7.5 1.4 1 0 0 1 1 1 0 MYND finger YL1_C PF08265.6 CAR21914.1 - 0.031 13.8 0.0 0.087 12.3 0.0 1.7 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain GerE PF00196.14 CAR21914.1 - 0.084 12.2 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family zf-Mss51 PF13824.1 CAR21914.1 - 0.52 10.2 8.7 1.1 9.1 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ATP-synt_E PF05680.7 CAR21914.1 - 1.7 8.6 5.6 0.82 9.6 2.0 2.0 2 1 0 2 2 2 0 ATP synthase E chain zf-B_box PF00643.19 CAR21914.1 - 2.5 8.0 11.5 1.8 8.5 6.0 2.0 2 0 0 2 2 2 0 B-box zinc finger Atg14 PF10186.4 CAR21914.1 - 8.7 5.1 7.9 11 4.9 5.5 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Suc_Fer-like PF06999.7 CAR21915.1 - 4.6e-37 128.2 0.0 6.2e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like CPSF_A PF03178.10 CAR21916.1 - 9e-56 189.2 0.0 2.5e-55 187.8 0.0 1.8 1 1 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CAR21916.1 - 5.4e-24 84.1 0.3 1e-23 83.2 0.2 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Gsf2 PF11055.3 CAR21917.1 - 2.9e-168 559.2 0.1 3.4e-168 559.0 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 Pox_I1 PF03289.8 CAR21918.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus protein I1 UPF0122 PF04297.9 CAR21920.1 - 0.19 11.7 6.8 1.6 8.7 0.4 3.0 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like LRR_6 PF13516.1 CAR21921.1 - 0.29 11.3 15.0 18 5.7 0.1 7.5 9 0 0 9 9 9 0 Leucine Rich repeat NOA36 PF06524.7 CAR21921.1 - 2.3 7.4 13.2 1.8 7.7 7.7 1.9 2 0 0 2 2 2 0 NOA36 protein DUF676 PF05057.9 CAR21922.1 - 2.9e-42 144.4 0.0 4.3e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CAR21922.1 - 0.0037 16.8 0.0 0.0089 15.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CAR21922.1 - 0.0055 16.3 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CAR21922.1 - 0.031 14.1 0.0 0.056 13.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1832 PF08870.6 CAR21922.1 - 0.049 13.3 0.0 0.29 10.8 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1832) Abhydrolase_5 PF12695.2 CAR21922.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 CAR21922.1 - 0.14 11.8 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Sedlin_N PF04628.8 CAR21923.1 - 1.3e-14 54.2 0.3 1.4e-14 54.0 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2004 PF09406.5 CAR21923.1 - 0.013 15.5 0.2 0.021 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) FAD_binding_2 PF00890.19 CAR21924.1 - 1.1e-71 241.8 0.1 1.3e-71 241.6 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CAR21924.1 - 3.6e-07 30.1 0.1 2.1e-06 27.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CAR21924.1 - 4e-07 29.2 0.2 5.1e-06 25.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CAR21924.1 - 7.5e-07 29.4 0.0 7.9e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR21924.1 - 3.9e-06 26.9 0.0 0.00019 21.3 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAR21924.1 - 4.6e-05 22.6 0.3 0.0082 15.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 CAR21924.1 - 0.00016 20.8 0.2 0.0012 17.9 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain IF2_N PF04760.10 CAR21924.1 - 0.00021 20.8 0.0 0.12 11.9 0.0 2.6 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region HI0933_like PF03486.9 CAR21924.1 - 0.0009 17.8 0.9 0.15 10.4 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.1 CAR21924.1 - 0.0012 18.6 0.1 0.013 15.2 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CAR21924.1 - 0.0015 17.5 0.1 0.12 11.2 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Beta_elim_lyase PF01212.16 CAR21925.1 - 8.3e-75 251.6 0.0 1e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase YL1_C PF08265.6 CAR21926.1 - 9.2e-14 50.7 0.8 1.9e-13 49.6 0.1 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Mac PF12464.3 CAR21927.1 - 2.8e-14 52.8 0.0 4.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 CAR21927.1 - 6.4e-12 44.4 15.9 1.2e-07 30.9 3.8 3.5 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CAR21927.1 - 7.2e-07 28.6 13.4 9.5e-06 25.0 2.1 3.3 3 1 2 5 5 5 4 Hexapeptide repeat of succinyl-transferase fn3 PF00041.16 CAR21928.1 - 0.00021 21.3 0.5 0.00081 19.4 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Isy1 PF06246.7 CAR21929.1 - 6.6e-56 189.5 2.7 7.7e-56 189.3 1.9 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DivIC PF04977.10 CAR21929.1 - 0.096 12.1 1.1 0.48 9.9 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Glyco_hydro_32N PF00251.15 CAR21930.1 - 2e-88 296.7 6.8 2.7e-88 296.2 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CAR21930.1 - 8.8e-09 35.6 0.2 4.9e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal GDA1_CD39 PF01150.12 CAR21931.1 - 1.7e-113 379.4 0.0 2e-113 379.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF2808 PF10989.3 CAR21931.1 - 0.16 11.6 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) NAD_kinase PF01513.16 CAR21932.1 - 2.8e-71 239.6 0.0 3.9e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 CAR21932.1 - 0.018 14.4 0.0 0.094 12.1 0.0 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DEP PF00610.16 CAR21932.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_hydro_16 PF00722.16 CAR21933.1 - 9.7e-43 145.6 7.8 2.5e-42 144.2 5.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 CAR21933.1 - 0.014 15.3 12.8 0.041 13.8 8.9 1.8 1 0 0 1 1 1 0 Chitin recognition protein FAM220 PF15487.1 CAR21933.1 - 5.3 6.3 11.3 10 5.4 7.9 1.4 1 0 0 1 1 1 0 FAM220 family Cytochrom_C PF00034.16 CAR21934.1 - 7.6e-09 36.2 0.6 1.7e-08 35.1 0.4 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CAR21934.1 - 1.5e-07 31.4 2.4 1.7e-06 28.0 1.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III RE_AlwI PF09491.5 CAR21934.1 - 0.023 13.2 0.0 0.023 13.2 0.0 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease Cytochrom_C550 PF14495.1 CAR21934.1 - 0.07 12.5 1.0 0.3 10.5 0.2 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain HAD_2 PF13419.1 CAR21935.1 - 1.3e-21 77.5 0.0 1.7e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR21935.1 - 0.0092 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like UBA PF00627.26 CAR21936.1 - 5.8e-24 83.2 2.3 5.4e-15 54.7 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 CAR21936.1 - 6.1e-17 60.7 1.4 2.2e-16 59.0 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin family XPC-binding PF09280.6 CAR21936.1 - 5.1e-14 51.4 0.3 5.1e-14 51.4 0.2 2.2 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.3 CAR21936.1 - 1.6e-08 34.0 1.4 1.6e-08 34.0 0.9 1.9 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CAR21936.1 - 9.1e-05 22.3 0.0 9.1e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Pex14_N PF04695.8 CAR21936.1 - 0.007 16.4 8.2 0.007 16.4 5.7 2.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CUE PF02845.11 CAR21936.1 - 0.0089 15.4 0.2 0.33 10.4 0.0 3.5 4 1 0 4 4 4 1 CUE domain UBA_3 PF09288.5 CAR21936.1 - 0.023 14.2 0.0 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain ThiS PF02597.15 CAR21936.1 - 0.038 14.4 0.6 0.33 11.4 0.0 2.6 3 0 0 3 3 2 0 ThiS family RAP1 PF07218.6 CAR21936.1 - 0.15 10.1 3.7 0.18 9.8 2.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3306 PF11748.3 CAR21936.1 - 0.31 11.6 21.7 0.044 14.4 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) PAT1 PF09770.4 CAR21936.1 - 0.5 8.5 25.4 0.62 8.2 17.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLD3 PF08639.5 CAR21936.1 - 0.8 8.2 15.5 0.7 8.4 3.4 2.2 2 0 0 2 2 2 0 DNA replication regulator SLD3 Zip PF02535.17 CAR21936.1 - 0.87 8.5 2.1 1.4 7.8 1.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.8 CAR21936.1 - 1.3 8.8 21.4 1.8 8.3 14.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2407 PF10302.4 CAR21936.1 - 1.8 8.8 9.9 5.8 7.1 6.9 2.0 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Apc15p PF05841.6 CAR21936.1 - 1.9 9.2 13.0 8.9 7.0 4.7 2.4 2 0 0 2 2 2 0 Apc15p protein DUF2291 PF10054.4 CAR21936.1 - 5.6 6.1 6.4 1.1 8.5 1.3 1.9 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) FAM176 PF14851.1 CAR21936.1 - 5.8 6.5 6.0 3.6 7.2 0.8 2.7 3 0 0 3 3 3 0 FAM176 family DUF1395 PF07160.7 CAR21936.1 - 7.3 6.0 9.1 14 5.0 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Anp1 PF03452.9 CAR21937.1 - 7.9e-121 402.3 0.0 1.1e-120 401.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 AAR2 PF05282.6 CAR21937.1 - 0.003 16.5 0.1 0.0043 16.0 0.1 1.1 1 0 0 1 1 1 1 AAR2 protein DUF1687 PF07955.6 CAR21937.1 - 0.18 11.7 0.9 0.4 10.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) eIF-5a PF01287.15 CAR21938.1 - 2.2e-28 98.0 0.3 3.2e-28 97.4 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CAR21938.1 - 0.00028 20.4 0.5 0.00052 19.6 0.4 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CAR21938.1 - 0.0063 16.3 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain zf-BED PF02892.10 CAR21939.1 - 4.7e-06 26.2 2.4 4.7e-06 26.2 1.6 1.9 2 1 0 2 2 2 1 BED zinc finger SOG2 PF10428.4 CAR21939.1 - 0.1 11.2 0.2 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MCM PF00493.18 CAR21940.1 - 4.1e-128 426.8 0.1 5.5e-128 426.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR21940.1 - 7e-23 81.4 0.0 2.1e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR21940.1 - 5.2e-08 32.2 0.0 1.4e-06 27.6 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAR21940.1 - 0.00036 20.1 0.1 0.0054 16.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAR21940.1 - 0.0061 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CAR21940.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hydrolase PF00702.21 CAR21941.1 - 1.5e-23 84.3 0.0 5.4e-23 82.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR21941.1 - 2.3e-22 80.0 0.0 3.9e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CAR21941.1 - 3.7e-19 68.6 0.0 7.5e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CAR21941.1 - 1e-08 34.9 0.0 2.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR21941.1 - 0.0005 19.7 0.1 0.0052 16.4 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RCC1_2 PF13540.1 CAR21941.1 - 0.038 13.6 0.9 0.25 11.0 0.1 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat S6PP PF05116.8 CAR21941.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Ku PF02735.11 CAR21943.1 - 5e-31 107.6 0.4 8.4e-31 106.9 0.3 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CAR21943.1 - 5.8e-25 88.0 1.0 1e-24 87.2 0.7 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CAR21943.1 - 1.4e-07 31.9 0.6 1.4e-07 31.9 0.4 2.4 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA PF00092.23 CAR21943.1 - 0.005 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Apis_Csd PF11671.3 CAR21943.1 - 0.011 15.4 0.8 0.72 9.6 0.0 2.9 3 0 0 3 3 3 0 Complementary sex determiner protein Exo_endo_phos PF03372.18 CAR21944.1 - 4.4e-22 79.2 0.0 5.8e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L30 PF00327.15 CAR21945.1 - 1.8e-13 49.8 0.1 3.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF3945 PF13101.1 CAR21945.1 - 0.055 12.7 0.2 0.15 11.4 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3945) RNB PF00773.14 CAR21947.1 - 1.5e-63 215.0 0.0 2.9e-63 214.1 0.0 1.5 1 0 0 1 1 1 1 RNB domain Init_tRNA_PT PF04179.7 CAR21948.1 - 2.6e-141 471.5 0.0 3e-141 471.3 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DUF3567 PF12091.3 CAR21948.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) ATP13 PF12921.2 CAR21949.1 - 5.6e-42 142.0 0.5 1.3e-41 140.8 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial ATPase expression Nyv1_N PF09426.5 CAR21949.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal PIG-L PF02585.12 CAR21950.1 - 1.5e-18 67.5 0.1 2.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase KcnmB2_inactiv PF09303.5 CAR21950.1 - 3 7.6 4.8 1.6 8.5 0.7 2.3 2 0 0 2 2 2 0 KCNMB2, ball and chain domain Fungal_trans PF04082.13 CAR21951.1 - 3.3e-37 127.7 0.7 6.4e-37 126.8 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR21951.1 - 2.4e-10 40.1 13.1 4.8e-10 39.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nab6_mRNP_bdg PF10567.4 CAR21952.1 - 2.1e-64 217.4 0.4 5.8e-64 216.0 0.2 1.8 1 0 0 1 1 1 1 RNA-recognition motif RRM PF10378.4 CAR21952.1 - 1.1e-16 60.1 5.5 1.1e-16 60.1 3.8 2.5 2 0 0 2 2 2 1 Putative RRM domain RRM_6 PF14259.1 CAR21952.1 - 3.2e-12 46.2 1.0 2.9e-05 23.9 0.0 4.4 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR21952.1 - 3e-05 23.5 1.9 0.38 10.4 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR21952.1 - 4.3e-05 23.2 0.3 0.003 17.3 0.0 3.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CAR21952.1 - 0.0013 18.5 0.1 0.32 10.8 0.0 2.9 2 0 0 2 2 2 1 RNA binding motif DUF1987 PF09345.5 CAR21952.1 - 0.025 14.3 0.4 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) MFS_1 PF07690.11 CAR21953.1 - 1.4e-40 139.0 42.1 1.4e-40 139.0 29.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR21953.1 - 3.8e-06 25.7 9.6 3.8e-06 25.7 6.7 2.8 3 2 0 3 3 3 2 Sugar (and other) transporter Anp1 PF03452.9 CAR21954.1 - 1.7e-123 411.0 0.0 2.1e-123 410.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CAR21954.1 - 0.012 15.3 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 BcsB PF03170.8 CAR21954.1 - 0.052 11.5 0.0 0.11 10.5 0.0 1.4 2 0 0 2 2 2 0 Bacterial cellulose synthase subunit Glyco_tranf_2_3 PF13641.1 CAR21954.1 - 0.14 11.9 0.0 1.6 8.4 0.0 2.4 3 0 0 3 3 3 0 Glycosyltransferase like family 2 S-methyl_trans PF02574.11 CAR21955.1 - 8.1e-85 284.7 0.0 9.1e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 CAR21955.1 - 0.0093 15.4 0.2 0.087 12.3 0.0 2.3 2 0 0 2 2 2 1 Kelch motif PGM_PMM_I PF02878.11 CAR21956.1 - 7.6e-39 132.3 0.0 1.3e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CAR21956.1 - 4.2e-21 75.2 0.0 8.5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CAR21956.1 - 4.8e-13 49.1 0.0 1.2e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CAR21956.1 - 1.2e-07 31.5 0.1 5.2e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Inhibitor_I42 PF09394.5 CAR21956.1 - 0.031 14.6 0.1 0.093 13.0 0.1 1.8 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 NIF PF03031.13 CAR21957.1 - 6.6e-25 87.6 0.3 3.5e-24 85.2 0.0 2.2 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 CAR21957.1 - 3.1e-10 40.0 0.1 9.3e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CAR21957.1 - 2.3e-05 24.1 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl_2 PF13533.1 CAR21957.1 - 0.0029 17.2 0.0 0.041 13.5 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like TAF8_C PF10406.4 CAR21958.1 - 1.6e-19 69.6 0.8 1.6e-19 69.6 0.6 2.6 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term DUF2695 PF10905.3 CAR21958.1 - 0.031 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Nbs1_C PF08599.5 CAR21958.1 - 0.15 11.9 7.3 5.6 6.9 1.4 3.2 3 0 0 3 3 3 0 DNA damage repair protein Nbs1 ubiquitin PF00240.18 CAR21959.1 - 2e-19 68.7 0.0 3.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAR21959.1 - 8.2e-11 41.4 0.1 1.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CAR21959.1 - 2e-06 27.4 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.4 CAR21959.1 - 0.00025 21.1 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CAR21959.1 - 0.0036 17.1 0.0 0.0074 16.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR21959.1 - 0.0065 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CTK3_C PF12350.3 CAR21961.1 - 2.5e-20 72.2 0.9 6e-20 71.0 0.6 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 CAR21961.1 - 5.6e-06 26.0 0.7 8.1e-05 22.2 0.5 2.5 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 Bul1_N PF04425.7 CAR21962.1 - 5.9e-157 522.7 1.7 5.9e-157 522.7 1.2 2.0 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 CAR21962.1 - 9.8e-99 329.9 13.2 9.8e-99 329.9 9.1 2.3 3 0 0 3 3 3 1 Bul1 C terminus Abi PF02517.11 CAR21963.1 - 1.1e-14 54.3 3.5 4e-14 52.5 2.4 1.9 1 0 0 1 1 1 1 CAAX protease self-immunity Zds_C PF08632.5 CAR21964.1 - 4.4e-32 109.2 0.6 7.4e-32 108.5 0.4 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF1892 PF08987.5 CAR21965.1 - 2e-39 134.1 1.9 2.2e-39 134.0 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) Cyt-b5 PF00173.23 CAR21966.1 - 7.9e-20 70.4 1.5 2e-19 69.1 0.2 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CAR21966.1 - 7.9e-12 45.5 17.1 7.9e-12 45.5 11.9 2.4 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 CAR21966.1 - 0.1 12.6 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region zf-C3HC PF07967.8 CAR21967.1 - 2.8e-12 46.5 0.4 1.1e-07 31.6 0.1 2.4 2 1 0 2 2 2 2 C3HC zinc finger-like Pribosyltran PF00156.22 CAR21968.1 - 3.3e-17 62.3 0.2 6.2e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SRP19 PF01922.12 CAR21969.1 - 2.2e-27 95.4 0.0 3.9e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein RRN9 PF10680.4 CAR21970.1 - 7.1e-17 60.9 0.2 1.7e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Caveolin PF01146.12 CAR21970.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Caveolin PXA PF02194.10 CAR21971.1 - 1.4e-36 125.8 3.7 1.4e-36 125.8 0.1 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 CAR21971.1 - 1.9e-22 79.4 0.1 6.1e-22 77.8 0.1 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 CAR21971.1 - 2.4e-14 53.0 5.9 2e-13 50.0 2.3 2.8 2 0 0 2 2 2 1 PX domain G-patch PF01585.18 CAR21972.1 - 0.00085 19.0 1.1 0.0034 17.1 0.8 2.1 1 1 0 1 1 1 1 G-patch domain DDHD PF02862.12 CAR21972.1 - 0.3 10.8 9.6 0.44 10.2 6.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 CAR21972.1 - 6.9 5.9 36.1 10 5.4 25.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 CAR21972.1 - 10 6.0 22.4 17 5.2 15.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RRM_1 PF00076.17 CAR21973.1 - 7.5e-38 128.0 0.1 8.5e-11 41.3 0.0 4.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR21973.1 - 1.7e-33 114.3 0.0 1.7e-10 40.7 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR21973.1 - 2.6e-19 68.7 0.0 1.5e-06 27.9 0.0 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 CAR21973.1 - 0.0001 21.5 0.1 0.00033 19.9 0.1 2.0 1 0 0 1 1 1 1 Lsm interaction motif DUF1866 PF08952.6 CAR21973.1 - 0.023 14.2 0.1 0.86 9.1 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1866) DUF4283 PF14111.1 CAR21973.1 - 0.089 11.8 0.0 0.32 10.0 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4283) Nup188 PF10487.4 CAR21974.1 - 1.6e-184 615.4 17.4 2.8e-184 614.6 12.1 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Pyrophosphatase PF00719.14 CAR21975.1 - 1.1e-48 164.6 0.0 1.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF221 PF02714.10 CAR21976.1 - 2.4e-109 365.1 30.3 2.4e-109 365.1 21.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CAR21976.1 - 8.1e-41 139.1 1.0 8.1e-41 139.1 0.7 3.0 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CAR21976.1 - 3.4e-31 106.9 0.1 1.3e-30 105.1 0.0 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 CAR21976.1 - 5.2e-21 74.9 0.8 1e-20 74.0 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF904 PF06005.7 CAR21976.1 - 0.032 14.5 0.1 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 CAR21976.1 - 0.41 10.7 1.0 0.84 9.7 0.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2410 PF10307.4 CAR21977.1 - 1.8e-57 193.9 0.7 2.8e-57 193.3 0.0 1.6 2 0 0 2 2 2 1 Hypothetical protein (DUF2410) WD40 PF00400.27 CAR21978.1 - 1.7e-30 103.7 8.0 1.8e-08 33.9 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR21978.1 - 2.4e-05 24.1 0.1 0.0059 16.3 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CAR21978.1 - 0.00011 21.1 0.0 0.015 14.1 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region Apc4_WD40 PF12894.2 CAR21978.1 - 0.0002 20.8 0.0 0.066 12.7 0.0 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 CAR21978.1 - 0.0013 16.9 0.3 0.0022 16.2 0.2 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 CAR21978.1 - 0.026 14.3 0.0 3.1 7.6 0.0 2.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region CUE PF02845.11 CAR21979.1 - 7.3e-09 34.9 0.1 1.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain Kei1 PF08552.6 CAR21979.1 - 0.18 11.4 1.6 0.26 10.9 1.0 1.3 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Bse634I PF07832.6 CAR21980.1 - 0.026 13.6 0.1 1.1 8.3 0.0 2.1 1 1 0 2 2 2 0 Cfr10I/Bse634I restriction endonuclease FerA PF08165.6 CAR21980.1 - 0.12 12.1 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 FerA (NUC095) domain HisKA_3 PF07730.8 CAR21980.1 - 0.13 12.6 0.3 0.56 10.5 0.1 2.1 2 0 0 2 2 2 0 Histidine kinase SAP30_Sin3_bdg PF13867.1 CAR21981.1 - 3.6e-16 58.7 0.1 6.5e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 TatD_DNase PF01026.16 CAR21982.1 - 1e-39 136.2 0.0 1.2e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Glyco_transf_20 PF00982.16 CAR21983.1 - 3.4e-163 543.5 0.0 9.4e-163 542.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CAR21983.1 - 1.9e-32 112.0 0.0 8.5e-32 109.9 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase eIF-1a PF01176.14 CAR21984.1 - 6.4e-27 92.7 0.2 8.6e-27 92.3 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 CAR21984.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mg_trans_NIPA PF05653.9 CAR21985.1 - 6.3e-111 370.1 15.4 7.4e-111 369.8 10.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CAR21985.1 - 2e-07 31.1 0.8 2e-07 31.1 0.5 3.7 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CAR21985.1 - 0.00018 21.5 6.9 0.00018 21.5 4.8 3.2 2 1 0 2 2 2 1 EamA-like transporter family Acyl_transf_3 PF01757.17 CAR21985.1 - 0.063 12.0 12.5 0.45 9.2 3.5 2.2 1 1 0 2 2 2 0 Acyltransferase family DUF2937 PF11157.3 CAR21985.1 - 0.12 11.6 1.4 0.28 10.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2428 PF10350.4 CAR21986.1 - 2.3e-62 210.3 0.1 5.6e-62 209.0 0.1 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 CAR21986.1 - 1.2e-05 25.5 0.9 2.3 8.5 0.2 4.7 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 CAR21986.1 - 6.7e-05 22.6 4.3 4.2 7.7 0.0 6.9 8 1 1 9 9 9 2 HEAT repeat DUF1262 PF06880.6 CAR21987.1 - 0.082 13.2 0.4 0.55 10.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1262) zf-RING_2 PF13639.1 CAR21989.1 - 7.1e-08 32.1 3.3 7.1e-08 32.1 2.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 CAR21989.1 - 1.1e-07 31.5 4.0 1.1e-07 31.5 2.8 2.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CAR21989.1 - 3.2e-07 29.9 2.1 3.2e-07 29.9 1.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR21989.1 - 6.8e-07 29.2 3.2 6.8e-07 29.2 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR21989.1 - 7.2e-07 28.7 3.8 7.2e-07 28.7 2.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAR21989.1 - 6.8e-06 26.1 8.8 4.2e-05 23.5 1.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CAR21989.1 - 1.8e-05 24.3 0.1 4e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CAR21989.1 - 1.9e-05 24.2 11.0 2e-05 24.1 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAR21989.1 - 0.00062 19.5 3.3 0.0015 18.2 0.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 CAR21989.1 - 0.0028 17.4 7.9 0.4 10.5 1.0 2.5 2 0 0 2 2 2 2 Double zinc ribbon zf-RING_3 PF14369.1 CAR21989.1 - 0.01 15.8 4.2 0.01 15.8 2.9 3.2 2 1 0 2 2 2 0 zinc-finger zinc_ribbon_5 PF13719.1 CAR21989.1 - 0.014 15.0 2.2 12 5.6 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAR21989.1 - 0.015 14.9 2.4 12 5.6 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.1 CAR21989.1 - 0.022 14.3 10.3 0.022 14.3 2.0 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RecR PF02132.10 CAR21989.1 - 0.029 13.7 1.0 0.029 13.7 0.7 2.2 2 0 0 2 2 2 0 RecR protein HypA PF01155.14 CAR21989.1 - 0.1 12.3 4.9 4.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 CAR21989.1 - 0.15 11.9 5.2 3.9 7.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons Ogr_Delta PF04606.7 CAR21989.1 - 0.28 10.8 0.2 0.28 10.8 0.1 3.4 4 1 0 4 4 4 0 Ogr/Delta-like zinc finger zf-RING_6 PF14835.1 CAR21989.1 - 1.1 9.0 8.7 4.2 7.2 1.8 2.5 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DUF1272 PF06906.6 CAR21989.1 - 3.4 7.6 9.8 2.1 8.2 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) COX7a PF02238.10 CAR21990.1 - 0.0078 15.9 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa G5 PF07501.7 CAR21992.1 - 0.11 12.4 1.2 0.2 11.6 0.8 1.4 1 0 0 1 1 1 0 G5 domain EamA PF00892.15 CAR21993.1 - 1e-26 93.4 23.0 1.8e-15 57.0 0.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CAR21993.1 - 2.5e-08 34.1 3.0 2.5e-08 34.1 2.1 3.6 2 1 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 CAR21993.1 - 0.00054 18.9 7.6 0.0012 17.8 5.4 1.5 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 CAR21993.1 - 0.0009 18.1 6.2 0.0009 18.1 4.3 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 CAR21993.1 - 0.097 12.3 15.4 0.025 14.2 0.6 2.8 2 2 0 2 2 2 0 Triose-phosphate Transporter family DUF4131 PF13567.1 CAR21993.1 - 1.3 8.3 14.0 1.8 7.9 1.4 3.9 3 1 0 4 4 4 0 Domain of unknown function (DUF4131) Amidase PF01425.16 CAR21995.1 - 1.2e-79 268.2 0.0 1.4e-79 267.9 0.0 1.1 1 0 0 1 1 1 1 Amidase UQ_con PF00179.21 CAR21996.1 - 7.2e-44 148.6 0.0 9.5e-44 148.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR21996.1 - 0.004 16.8 0.0 0.014 15.1 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B NOA36 PF06524.7 CAR21996.1 - 0.092 11.9 15.4 0.12 11.5 10.7 1.1 1 0 0 1 1 1 0 NOA36 protein Dfp1_Him1_M PF08630.5 CAR21998.1 - 7.6e-44 148.4 0.0 1.5e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 CAR21998.1 - 8e-19 67.0 2.9 1.6e-18 66.1 2.0 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.21 CAR21999.1 - 9e-11 41.4 10.2 1.5e-05 25.0 1.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR21999.1 - 5.8e-06 26.3 0.4 5.8e-06 26.3 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR21999.1 - 0.0046 17.1 10.4 0.057 13.7 1.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CAR21999.1 - 0.018 15.2 6.6 1.7 8.9 1.2 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR21999.1 - 0.42 10.8 6.3 6.2 7.0 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CAR21999.1 - 9.5 6.6 8.7 1.5 9.1 1.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Glyco_hydro_81 PF03639.8 CAR22000.1 - 2.2e-250 832.4 16.3 2.2e-250 832.4 11.3 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 TPR_11 PF13414.1 CAR22002.1 - 6.5e-11 41.7 4.3 5.7e-07 29.0 0.0 4.5 5 1 1 6 6 6 2 TPR repeat TPR_2 PF07719.12 CAR22002.1 - 8.7e-11 40.8 2.9 0.082 12.8 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAR22002.1 - 2.8e-06 26.6 1.1 1.3 8.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR22002.1 - 3.4e-05 24.0 3.7 1.5 9.2 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAR22002.1 - 4e-05 23.4 0.2 0.0093 16.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR22002.1 - 4e-05 23.4 0.4 0.011 15.6 0.1 5.8 3 1 3 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.5 CAR22002.1 - 0.00037 19.3 0.5 0.07 11.8 0.0 2.8 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.1 CAR22002.1 - 0.0015 18.1 2.8 1.1 9.1 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR22002.1 - 0.011 15.7 1.0 3.3 7.9 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CAR22002.1 - 0.9 10.3 14.8 19 6.2 0.1 6.7 6 2 2 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAR22002.1 - 1.6 9.4 7.9 15 6.4 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M28 PF04389.12 CAR22003.1 - 3.1e-30 105.2 0.0 8.9e-30 103.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 CAR22003.1 - 2.9e-05 23.6 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CAR22003.1 - 0.00046 19.0 0.0 0.0025 16.6 0.0 1.9 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase URO-D PF01208.12 CAR22004.1 - 3.1e-120 401.1 0.0 3.5e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PSP PF04046.11 CAR22004.1 - 0.038 13.3 0.5 0.086 12.2 0.1 1.8 2 0 0 2 2 2 0 PSP Ank_5 PF13857.1 CAR22005.1 - 4.9e-06 26.6 0.1 1.1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR22005.1 - 0.0031 17.8 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SNF2_N PF00176.18 CAR22006.1 - 4.2e-61 206.3 0.1 6.1e-61 205.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR22006.1 - 3.3e-11 42.8 0.0 9.6e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR22006.1 - 2.2e-09 37.0 0.1 4.6e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CAR22006.1 - 5.9e-09 35.1 0.1 1e-07 31.0 0.1 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CAR22006.1 - 4e-07 30.0 0.0 1.5e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2439 PF10382.4 CAR22006.1 - 0.046 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) Coiled PF05710.7 CAR22007.1 - 2 8.9 8.6 0.1 13.0 1.9 1.9 2 0 0 2 2 2 0 Coiled coil Alg14 PF08660.6 CAR22008.1 - 8.2e-50 169.1 0.0 1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TIM PF00121.13 CAR22009.1 - 7.3e-91 303.5 0.2 8.2e-91 303.4 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase His_Phos_1 PF00300.17 CAR22010.1 - 2e-35 122.2 0.0 4.5e-35 121.0 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Thioredoxin PF00085.15 CAR22011.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_6 PF13848.1 CAR22011.1 - 0.049 13.4 0.0 0.087 12.6 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain CX PF01705.14 CAR22011.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 CX module AA_permease PF00324.16 CAR22012.1 - 7.8e-121 403.7 41.9 9.4e-121 403.4 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR22012.1 - 1.1e-35 123.0 37.5 1.1e-35 123.0 26.0 1.4 1 1 1 2 2 2 1 Amino acid permease tRNA-synt_2 PF00152.15 CAR22013.1 - 5e-89 298.3 0.3 7.6e-89 297.7 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR22013.1 - 2.8e-12 46.3 0.1 5.7e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CAR22013.1 - 7.6e-08 31.8 0.3 0.0014 17.8 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CAR22013.1 - 0.049 13.2 0.5 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) FtsJ PF01728.14 CAR22014.1 - 6.5e-65 218.5 0.0 8.1e-65 218.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CAR22014.1 - 0.034 13.7 0.0 1.1 8.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_S10 PF00338.17 CAR22015.1 - 6.1e-29 99.7 0.0 1.7e-28 98.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e zf-RING_2 PF13639.1 CAR22016.1 - 4.4e-10 39.2 12.3 8.5e-10 38.3 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR22016.1 - 6.9e-06 26.0 10.3 1.4e-05 25.1 7.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAR22016.1 - 0.00053 19.7 5.2 0.00089 19.0 3.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CAR22016.1 - 0.0064 16.1 10.7 0.0064 16.1 7.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR22016.1 - 0.0079 15.8 8.0 0.014 15.0 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR22016.1 - 0.031 14.0 9.2 0.058 13.1 6.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR22016.1 - 0.072 13.1 13.7 0.077 13.0 8.7 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CH PF00307.26 CAR22016.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain Ribosomal_S3Ae PF01015.13 CAR22016.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal S3Ae family FANCL_C PF11793.3 CAR22016.1 - 0.26 11.2 7.3 1.4 8.9 5.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.9 CAR22016.1 - 6.1 6.3 11.2 0.13 11.7 1.1 2.2 1 1 0 2 2 2 0 P-11 zinc finger FYVE PF01363.16 CAR22017.1 - 2.9 7.8 13.6 0.57 10.1 6.4 2.1 1 1 0 1 1 1 0 FYVE zinc finger Actin PF00022.14 CAR22018.1 - 5.6e-53 179.7 0.0 7.5e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Actin NuA4 PF09340.5 CAR22019.1 - 8.3e-22 76.6 0.6 1e-21 76.3 0.4 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Sds3 PF08598.6 CAR22019.1 - 0.023 14.2 1.0 0.027 14.0 0.7 1.1 1 0 0 1 1 1 0 Sds3-like MRP-L28 PF09812.4 CAR22019.1 - 0.051 13.4 1.0 0.06 13.1 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF3896 PF13035.1 CAR22019.1 - 0.13 12.3 1.4 0.21 11.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Bap31 PF05529.7 CAR22019.1 - 0.18 11.2 2.0 0.26 10.7 1.4 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Prp19 PF08606.6 CAR22019.1 - 1.9 8.2 6.1 4 7.2 0.4 2.3 1 1 1 2 2 2 0 Prp19/Pso4-like AIM24 PF01987.12 CAR22020.1 - 1.5e-07 31.0 0.0 2.9e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 tRNA-synt_His PF13393.1 CAR22021.1 - 1.2e-42 146.0 0.1 1.1e-41 142.8 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CAR22021.1 - 6.4e-18 64.9 0.0 1.8e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR22021.1 - 3.1e-11 43.0 0.0 7e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CAR22021.1 - 0.0086 14.8 0.0 0.66 8.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) ADK_lid PF05191.9 CAR22021.1 - 0.071 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid IDO PF01231.13 CAR22022.1 - 1.3e-162 541.1 0.0 1.5e-162 540.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cid2 PF09774.4 CAR22023.1 - 1.5e-29 103.0 0.8 1.8e-29 102.7 0.6 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Lgl_C PF08596.5 CAR22024.1 - 7.1e-130 433.0 0.1 1.3e-129 432.1 0.1 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CAR22024.1 - 3.5e-08 33.0 3.6 1.2 9.1 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Pkinase PF00069.20 CAR22025.1 - 1.3e-63 214.6 0.0 4e-63 212.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22025.1 - 3.4e-35 121.3 0.0 7.9e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CAR22025.1 - 1e-30 105.2 24.6 2.6e-15 55.8 4.2 2.7 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CAR22025.1 - 5.2e-19 67.7 36.4 5.5e-10 38.8 11.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CAR22025.1 - 3.4e-12 46.6 1.1 1.1e-11 45.0 0.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR22025.1 - 0.0036 16.3 2.8 0.0046 15.9 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Syntaxin-6_N PF09177.6 CAR22025.1 - 1.6 9.2 11.6 0.74 10.2 2.5 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal zf-tcix PF14952.1 CAR22025.1 - 8.7 5.7 11.7 0.92 8.8 1.4 2.8 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-RING_2 PF13639.1 CAR22026.1 - 1.2 9.0 11.1 0.54 10.1 2.0 3.4 3 0 0 3 3 3 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 CAR22027.1 - 9.6e-30 102.8 8.5 9.6e-30 102.8 5.9 2.7 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CAR22027.1 - 1.9e-27 95.2 6.5 1.9e-27 95.2 4.5 3.4 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CAR22027.1 - 5.5e-14 51.1 3.5 5.5e-14 51.1 2.4 2.6 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 CAR22027.1 - 5e-11 43.1 4.3 6e-11 42.8 1.7 2.1 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD PF00628.24 CAR22027.1 - 1.1e-08 34.5 8.0 1.1e-08 34.5 5.5 2.7 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CAR22027.1 - 0.042 13.5 27.2 0.51 10.1 5.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CDC37_N PF03234.9 CAR22027.1 - 0.29 11.4 4.0 0.097 12.9 0.7 1.7 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding zf-RING-like PF08746.6 CAR22027.1 - 0.36 10.8 27.3 0.4 10.7 9.8 2.8 2 1 0 2 2 2 0 RING-like domain HLH PF00010.21 CAR22028.1 - 5.9e-12 45.1 0.9 1.1e-11 44.2 0.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 CAR22029.1 - 6e-31 106.9 14.9 8.1e-31 106.5 10.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family MFS_1 PF07690.11 CAR22029.1 - 2.1e-06 26.6 3.1 2.3e-06 26.5 2.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Arrestin_C PF02752.17 CAR22030.1 - 3.8e-21 75.6 0.5 1.1e-20 74.1 0.3 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CAR22030.1 - 0.0011 18.8 0.3 0.025 14.4 0.2 2.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Adaptin_N PF01602.15 CAR22031.1 - 4e-110 368.6 11.4 4.9e-110 368.3 7.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CAR22031.1 - 1.6e-09 38.0 0.0 3.1e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF2262 PF10020.4 CAR22031.1 - 0.012 15.7 1.3 0.035 14.3 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) TB2_DP1_HVA22 PF03134.14 CAR22032.1 - 7.8e-32 108.8 4.6 1e-31 108.4 3.2 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Glyco_hydro_65m PF03632.10 CAR22033.1 - 6.9e-98 327.7 0.1 4.2e-97 325.1 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 CAR22033.1 - 3.8e-22 78.8 0.0 7.4e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 CAR22033.1 - 4.9e-09 36.1 0.0 1.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain ATP-synt_ab PF00006.20 CAR22034.1 - 8.8e-71 237.8 0.0 1.5e-70 237.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAR22034.1 - 2e-27 95.9 0.4 5.2e-27 94.5 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAR22034.1 - 2.3e-17 62.9 2.4 5.5e-17 61.7 1.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CAR22034.1 - 0.0019 18.0 1.2 0.0041 16.9 0.8 1.6 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 CAR22034.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tex_N PF09371.5 CAR22034.1 - 0.051 12.8 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Cyclin_N PF00134.18 CAR22035.1 - 9.8e-09 34.8 0.9 1.4e-08 34.3 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 CAR22035.1 - 0.007 16.1 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Transcription factor TFIIB repeat ThiF PF00899.16 CAR22035.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family Peptidase_M41 PF01434.13 CAR22036.1 - 1.8e-70 236.7 0.3 3e-70 236.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAR22036.1 - 3.7e-41 140.4 0.0 1.2e-40 138.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR22036.1 - 1.2e-05 25.3 0.1 4.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CAR22036.1 - 8.9e-05 22.6 0.1 0.039 14.0 0.1 3.1 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CAR22036.1 - 0.00032 19.5 0.0 0.0006 18.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 CAR22036.1 - 0.00077 20.2 0.0 0.0027 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR22036.1 - 0.0012 18.4 1.5 0.004 16.8 1.1 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CAR22036.1 - 0.0017 17.4 0.0 0.005 15.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CAR22036.1 - 0.0023 17.6 0.1 0.011 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAR22036.1 - 0.0044 16.4 1.0 0.11 11.9 0.3 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR22036.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CAR22036.1 - 0.014 15.3 0.0 0.065 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CAR22036.1 - 0.018 14.1 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CAR22036.1 - 0.024 14.9 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CAR22036.1 - 0.032 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CAR22036.1 - 0.049 12.7 0.3 0.1 11.7 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CAR22036.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CAR22036.1 - 0.11 11.5 0.1 0.49 9.4 0.0 2.0 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 CAR22036.1 - 0.12 11.5 0.3 0.3 10.3 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein Peptidase_M50B PF13398.1 CAR22036.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Cnd2 PF05786.9 CAR22037.1 - 1.6e-137 460.0 23.2 2.3e-137 459.5 16.1 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 FAD_binding_3 PF01494.14 CAR22038.1 - 2.8e-18 66.1 0.0 5.8e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CAR22038.1 - 3.7e-07 29.3 0.0 6.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAR22038.1 - 8.1e-07 28.9 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CAR22038.1 - 5.2e-06 25.5 0.0 7.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 CAR22038.1 - 2.1e-05 24.8 0.1 8.6e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CAR22038.1 - 5.6e-05 22.8 0.0 9.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CAR22038.1 - 0.00029 20.3 0.2 0.00083 18.8 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 CAR22038.1 - 0.00042 19.7 0.1 0.00094 18.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 CAR22038.1 - 0.00097 19.0 0.2 0.0021 17.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAR22038.1 - 0.0014 17.5 0.2 0.0022 16.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 CAR22038.1 - 0.0016 17.3 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.9 CAR22038.1 - 0.0031 16.0 0.1 0.006 15.1 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 CAR22038.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 CAR22038.1 - 0.046 12.8 1.2 0.074 12.1 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 CAR22038.1 - 0.05 13.4 0.2 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 CAR22038.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CAR22038.1 - 0.073 11.6 0.1 4.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_2 PF03446.10 CAR22038.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.19 CAR22039.1 - 3.5e-83 279.6 30.3 4.3e-83 279.3 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR22039.1 - 4.2e-12 45.4 46.9 2.5e-10 39.6 33.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily 4HBT PF03061.17 CAR22040.1 - 1.9e-06 27.8 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily ArfGap PF01412.13 CAR22041.1 - 5.5e-34 116.4 0.3 1.1e-33 115.4 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf A2L_zn_ribbon PF08792.5 CAR22041.1 - 0.14 11.6 1.5 0.84 9.1 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain DZR PF12773.2 CAR22041.1 - 0.18 11.6 0.9 0.36 10.6 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Rox3 PF08633.5 CAR22042.1 - 2.2e-59 201.0 1.0 2.6e-59 200.7 0.7 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit RIIa PF02197.12 CAR22042.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF566 PF04484.7 CAR22043.1 - 7.7 5.9 8.4 10 5.5 5.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_L32e PF01655.13 CAR22044.1 - 1.7e-47 160.0 2.1 1.9e-47 159.8 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Motile_Sperm PF00635.21 CAR22045.1 - 1.4e-25 89.0 0.0 2.7e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Peptidase_M24 PF00557.19 CAR22046.1 - 1.1e-50 172.0 0.0 1.4e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S21 PF01165.15 CAR22047.1 - 6.2e-09 35.1 2.2 1.2e-08 34.2 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Aa_trans PF01490.13 CAR22048.1 - 4.9e-106 354.6 21.1 5.9e-106 354.3 14.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.1 CAR22048.1 - 2.2 7.9 13.4 0.16 11.6 0.3 3.4 3 1 1 4 4 4 0 Alpha/beta-hydrolase family N-terminus SH3_1 PF00018.23 CAR22049.1 - 3.4e-10 39.1 0.1 6.3e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR22049.1 - 4.3e-09 35.8 0.0 7.6e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR22049.1 - 2.6e-07 29.9 0.1 8.8e-07 28.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain zf-DHHC PF01529.15 CAR22049.1 - 0.52 9.6 2.6 0.84 9.0 1.8 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase PI3_PI4_kinase PF00454.22 CAR22050.1 - 6.1e-47 160.0 0.0 1.3e-46 158.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 CAR22050.1 - 3.1e-23 82.2 0.1 1.6e-22 79.9 0.0 2.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 CAR22050.1 - 7.4e-13 47.6 0.0 2.5e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 FATC domain Ribosomal_L14 PF00238.14 CAR22051.1 - 4.6e-31 107.0 0.0 5.2e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-C3HC4 PF00097.20 CAR22052.1 - 2.9e-10 39.6 5.9 4.3e-10 39.0 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR22052.1 - 5.8e-10 38.6 4.9 9e-10 38.0 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR22052.1 - 6.9e-10 38.6 7.6 1.1e-09 37.9 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAR22052.1 - 1e-08 35.0 7.1 1.7e-08 34.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR22052.1 - 5.2e-08 32.4 6.7 8.4e-08 31.8 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CAR22052.1 - 4.2e-07 29.5 3.1 7.1e-07 28.8 2.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAR22052.1 - 5.1e-05 23.0 7.6 8e-05 22.4 5.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CAR22052.1 - 0.002 17.9 2.6 0.003 17.3 1.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CAR22052.1 - 0.036 14.1 3.4 0.065 13.3 2.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CAR22052.1 - 0.085 12.4 6.8 0.73 9.4 5.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 CAR22052.1 - 0.74 9.3 5.6 1.7 8.2 3.9 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger FYVE PF01363.16 CAR22052.1 - 1.2 9.0 6.0 0.51 10.2 2.2 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_6 PF14835.1 CAR22052.1 - 2 8.2 5.7 19 5.1 4.0 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein NT-C2 PF10358.4 CAR22054.1 - 2.9e-48 163.0 2.4 1.2e-47 160.9 1.7 1.8 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins PH PF00169.24 CAR22056.1 - 2.3e-14 53.4 0.0 8e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 CAR22056.1 - 9.4e-13 47.3 0.2 1.9e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 CAR22056.1 - 2.8e-10 39.8 0.0 5.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 CAR22056.1 - 5.3e-09 36.3 0.0 3.5e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_9 PF14604.1 CAR22056.1 - 1.7e-08 33.9 0.1 3.3e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR22056.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 CAR22056.1 - 0.0013 18.7 0.0 0.056 13.5 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_11 PF13414.1 CAR22057.1 - 9.8e-40 134.0 22.4 3e-13 49.1 0.4 7.6 4 3 5 9 9 9 7 TPR repeat TPR_2 PF07719.12 CAR22057.1 - 2e-38 127.2 13.9 5.6e-07 28.9 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.23 CAR22057.1 - 3.3e-37 124.5 16.5 2.7e-08 33.0 0.2 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat Apc3 PF12895.2 CAR22057.1 - 7.7e-29 99.6 22.7 4e-17 62.1 0.8 4.7 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CAR22057.1 - 1.5e-26 90.1 1.5 0.00029 20.3 0.0 9.1 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAR22057.1 - 7.3e-22 77.4 4.5 7e-07 29.7 0.0 6.9 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 CAR22057.1 - 7e-18 63.2 7.0 0.0011 18.9 0.1 9.4 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAR22057.1 - 2.6e-16 59.2 17.7 0.00049 19.9 0.1 7.7 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAR22057.1 - 1.2e-13 51.1 8.0 1.7e-05 25.0 0.0 6.5 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR22057.1 - 2.7e-13 49.2 0.4 0.024 15.2 0.0 8.7 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR22057.1 - 2.2e-09 36.9 4.1 6.9e-05 22.6 0.1 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR22057.1 - 9.1e-09 34.4 11.1 5.6 7.0 0.0 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAR22057.1 - 1.3e-07 31.5 15.4 0.44 11.1 0.0 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_15 PF13429.1 CAR22057.1 - 9.6e-07 28.1 0.1 0.2 10.6 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 CAR22057.1 - 0.00068 19.1 2.4 0.13 11.6 0.4 3.3 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.9 CAR22057.1 - 0.002 18.4 4.1 4.8 7.9 0.0 5.7 8 0 0 8 8 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CAR22057.1 - 0.018 15.2 0.1 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_20 PF14561.1 CAR22057.1 - 0.02 15.0 0.1 1.9 8.6 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 CAR22057.1 - 0.029 13.1 0.0 0.22 10.2 0.0 2.1 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 CAR22057.1 - 0.084 12.8 0.7 14 5.8 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR22057.1 - 0.11 12.4 3.5 37 4.2 0.0 4.7 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 CAR22057.1 - 0.16 11.7 6.6 12 5.6 0.0 4.8 4 1 1 5 5 4 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 CAR22057.1 - 0.72 9.7 5.4 8.6 6.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat EMP70 PF02990.11 CAR22058.1 - 3.7e-92 309.4 35.2 2e-53 181.6 0.0 3.9 3 1 0 3 3 3 3 Endomembrane protein 70 LSM PF01423.17 CAR22059.1 - 4.3e-17 61.4 0.7 7.5e-17 60.6 0.5 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAR22059.1 - 0.019 14.8 0.1 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Ank_4 PF13637.1 CAR22060.1 - 2.8e-11 43.6 2.8 0.00023 21.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CAR22060.1 - 1.9e-07 31.2 0.6 0.014 15.7 0.6 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAR22060.1 - 1e-06 28.7 5.5 0.013 15.7 0.5 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR22060.1 - 1.3e-05 25.0 5.2 0.015 15.4 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CAR22060.1 - 5e-05 22.9 6.8 0.0032 17.2 0.7 3.4 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 CAR22060.1 - 6.4e-05 22.5 1.5 6.4e-05 22.5 1.0 2.7 2 1 0 2 2 2 1 KilA-N domain HEAT_EZ PF13513.1 CAR22061.1 - 2.4e-20 72.4 0.7 0.00017 21.9 0.0 8.1 7 0 0 7 7 7 3 HEAT-like repeat HEAT PF02985.17 CAR22061.1 - 2e-14 52.2 3.3 0.017 15.1 0.0 8.0 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 CAR22061.1 - 3.4e-14 52.8 4.2 0.0067 16.6 0.0 6.8 5 1 1 6 6 6 3 HEAT repeats IBN_N PF03810.14 CAR22061.1 - 1.8e-10 40.5 2.0 7e-07 29.0 0.0 3.8 3 0 0 3 3 3 2 Importin-beta N-terminal domain Ipi1_N PF12333.3 CAR22061.1 - 1.2e-05 25.1 2.2 1.1 9.2 0.0 5.7 6 0 0 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 CAR22061.1 - 1.5e-05 25.3 2.0 0.15 12.4 0.0 5.7 4 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Cohesin_load PF10345.4 CAR22061.1 - 0.0018 16.6 0.1 0.03 12.5 0.0 2.3 2 0 0 2 2 2 1 Cohesin loading factor Sec7_N PF12783.2 CAR22061.1 - 0.0069 15.8 0.9 0.07 12.5 0.0 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_PBS PF03130.11 CAR22061.1 - 0.035 14.5 1.4 12 6.6 0.1 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 CAR22061.1 - 7 6.6 15.3 36 4.3 0.0 7.7 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat ALG3 PF05208.8 CAR22062.1 - 9.5e-126 419.9 28.0 1.2e-125 419.6 19.4 1.1 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.6 CAR22063.1 - 3.3e-07 29.8 0.4 6e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 LisH WD40 PF00400.27 CAR22064.1 - 1.1e-27 94.8 2.7 1.6e-05 24.5 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 CAR22064.1 - 0.00053 18.2 0.2 0.014 13.5 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 SOBP PF15279.1 CAR22065.1 - 0.039 14.3 9.7 0.072 13.4 6.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein GatB_N PF02934.10 CAR22066.1 - 1.9e-92 309.2 0.0 2.4e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CAR22066.1 - 2.4e-29 101.9 0.1 3.6e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 GatB domain MAM1 PF10434.4 CAR22068.1 - 9.5e-19 67.6 0.9 8.8e-18 64.4 0.6 2.0 1 1 0 1 1 1 1 Monopolin complex protein MAM1 Nucleoporin_C PF03177.9 CAR22069.1 - 5.7e-129 431.3 7.6 9.6e-129 430.5 5.3 1.4 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CAR22069.1 - 7.7e-112 374.1 7.3 1.1e-111 373.6 5.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Atg8 PF02991.11 CAR22070.1 - 1.1e-50 169.8 0.1 1.3e-50 169.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CAR22070.1 - 1.9e-08 34.3 0.0 2.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 NAM-associated PF14303.1 CAR22071.1 - 1.2 9.4 7.8 1.6 9.0 5.4 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain tRNA-synt_1 PF00133.17 CAR22072.1 - 1.6e-228 759.6 0.4 3.9e-227 755.0 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CAR22072.1 - 1.5e-27 96.1 0.0 4.4e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CAR22072.1 - 1.3e-19 70.1 0.6 4.2e-07 28.9 0.3 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CAR22072.1 - 7.6e-05 21.9 0.0 0.0007 18.8 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain HSP70 PF00012.15 CAR22073.1 - 7.1e-268 889.5 7.9 8.1e-268 889.3 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR22073.1 - 2.8e-16 59.0 0.2 2.5e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CAR22073.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CAR22073.1 - 0.043 12.6 0.5 0.35 9.6 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain AAR2 PF05282.6 CAR22074.1 - 6.4e-59 199.7 0.0 7.6e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Metallothio_11 PF02066.10 CAR22074.1 - 0.036 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Metallothionein family 11 Ribosomal_S8e PF01201.17 CAR22075.1 - 5.1e-52 175.4 2.2 5.9e-52 175.2 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.8 CAR22076.1 - 8.3e-24 82.8 1.6 1.2e-23 82.3 1.1 1.2 1 0 0 1 1 1 1 CSL zinc finger ATPase-cat_bd PF12156.3 CAR22076.1 - 0.018 15.5 0.1 0.056 13.9 0.0 1.7 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase TF_Zn_Ribbon PF08271.7 CAR22076.1 - 0.026 13.8 1.0 0.026 13.8 0.7 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_4 PF14570.1 CAR22076.1 - 0.12 11.9 0.8 0.23 11.0 0.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ADH_zinc_N_2 PF13602.1 CAR22077.1 - 8.4e-13 49.3 0.0 1.7e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR22077.1 - 2.5e-06 27.2 0.0 4.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR22077.1 - 0.047 13.2 0.0 5.9 6.4 0.0 2.7 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1793 PF08760.6 CAR22077.1 - 0.047 13.5 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) UQ_con PF00179.21 CAR22078.1 - 7.9e-30 103.1 0.1 1.4e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR22078.1 - 0.0015 18.2 0.0 0.0061 16.3 0.0 1.9 1 1 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 CAR22078.1 - 0.045 13.6 0.1 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 RWD domain Tn7_Tnp_TnsA_C PF08721.6 CAR22078.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 TnsA endonuclease C terminal Spore_III_AF PF09581.5 CAR22078.1 - 0.14 12.0 1.5 0.22 11.3 1.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Wbp11 PF09429.5 CAR22078.1 - 0.14 12.1 5.0 0.49 10.4 1.0 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 Pribosyltran_N PF13793.1 CAR22079.1 - 3.5e-46 155.6 0.2 7.4e-44 148.1 0.0 2.4 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CAR22079.1 - 2.1e-36 125.3 0.7 2.5e-30 105.5 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CAR22079.1 - 2.6e-12 46.5 2.0 4.4e-12 45.8 0.3 2.1 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UCH PF00443.24 CAR22080.1 - 3e-73 246.2 0.1 8.9e-73 244.7 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR22080.1 - 2.2e-21 76.5 3.8 1.9e-16 60.3 0.2 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.13 CAR22081.1 - 2.5e-24 85.5 1.9 4.3e-24 84.8 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR22081.1 - 3.9e-09 36.2 10.3 6.4e-09 35.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAS20 PF02064.10 CAR22081.1 - 0.008 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 MAS20 protein import receptor AhpC-TSA PF00578.16 CAR22082.1 - 8.2e-34 115.9 0.0 1.1e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CAR22082.1 - 6.3e-15 54.5 0.6 1.1e-14 53.7 0.4 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CAR22082.1 - 6.7e-11 41.9 0.0 9.4e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin Hypoth_Ymh PF09509.5 CAR22082.1 - 0.16 11.6 0.1 8.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) Sel1 PF08238.7 CAR22083.1 - 2.9e-45 151.6 16.2 1.5e-08 34.9 0.3 7.6 7 0 0 7 7 7 7 Sel1 repeat Rad51 PF08423.6 CAR22084.1 - 2.8e-138 458.9 0.0 3.7e-138 458.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CAR22084.1 - 2.1e-14 53.3 0.0 3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 CAR22084.1 - 2.1e-11 43.8 0.6 2.1e-11 43.8 0.4 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 CAR22084.1 - 6.9e-11 41.7 0.0 9.5e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CAR22084.1 - 1.2e-06 27.8 0.0 2.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 CAR22084.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 CAR22084.1 - 0.024 13.4 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HHH PF00633.18 CAR22084.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif PAXNEB PF05625.6 CAR22084.1 - 0.12 11.1 0.1 0.2 10.4 0.1 1.3 1 0 0 1 1 1 0 PAXNEB protein Sec7 PF01369.15 CAR22085.1 - 1.2e-25 90.2 1.5 5.2e-25 88.2 0.1 2.4 2 1 1 3 3 3 1 Sec7 domain Proteasome PF00227.21 CAR22086.1 - 6.3e-40 136.4 0.0 7.6e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Asp PF00026.18 CAR22086.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Cmc1 PF08583.5 CAR22087.1 - 1e-15 57.2 7.3 1e-15 57.2 5.1 1.9 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like HBS1_N PF08938.5 CAR22087.1 - 0.004 17.2 1.4 0.015 15.4 0.5 2.2 1 1 1 2 2 2 1 HBS1 N-terminus CBM_14 PF01607.19 CAR22087.1 - 0.012 15.4 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain CHCH PF06747.8 CAR22087.1 - 0.045 13.6 2.1 6.7 6.7 0.1 2.3 2 0 0 2 2 2 0 CHCH domain NDUF_B7 PF05676.8 CAR22087.1 - 0.15 11.5 4.1 0.25 10.7 2.8 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MFS_2 PF13347.1 CAR22088.1 - 0.034 12.5 0.1 0.036 12.4 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein RICTOR_N PF14664.1 CAR22089.1 - 3.8e-82 275.8 0.2 8.1e-82 274.7 0.1 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 CAR22089.1 - 1e-78 263.4 1.2 2.3e-76 255.7 0.4 2.8 2 1 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 CAR22089.1 - 5.4e-31 106.3 0.2 3.3e-28 97.4 0.1 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 CAR22089.1 - 6.2e-31 106.7 0.1 3.8e-30 104.1 0.0 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.18 CAR22089.1 - 0.0018 18.0 0.7 0.055 13.3 0.0 3.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat GlnE PF03710.10 CAR22089.1 - 0.038 13.2 0.2 0.13 11.5 0.1 1.9 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase ATG_C PF09333.6 CAR22089.1 - 0.12 12.5 0.1 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 ATG C terminal domain HEAT PF02985.17 CAR22089.1 - 1.2 9.3 4.3 13 6.1 0.1 4.0 5 0 0 5 5 5 0 HEAT repeat Caudo_TAP PF02413.12 CAR22090.1 - 0.0016 18.5 1.2 0.0021 18.2 0.9 1.2 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein PilO PF04350.8 CAR22090.1 - 0.07 13.0 2.4 0.094 12.5 1.7 1.2 1 0 0 1 1 1 0 Pilus assembly protein, PilO CDC37_N PF03234.9 CAR22090.1 - 0.12 12.6 2.8 0.18 12.1 1.9 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Meth_synt_2 PF01717.13 CAR22092.1 - 2.2e-145 483.6 0.0 2.6e-138 460.4 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CAR22092.1 - 2.9e-130 434.0 0.1 8.4e-117 389.8 0.1 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 CAR22092.1 - 0.056 12.3 0.0 0.57 9.0 0.0 2.5 3 0 0 3 3 3 0 Uroporphyrinogen decarboxylase (URO-D) SEP PF08059.8 CAR22093.1 - 5.8e-27 93.8 0.3 5.8e-27 93.8 0.2 1.7 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 CAR22093.1 - 8e-13 48.2 0.0 1.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain IER PF05760.7 CAR22093.1 - 0.0006 19.8 2.6 0.2 11.5 0.0 2.2 2 0 0 2 2 2 2 Immediate early response protein (IER) UBA_4 PF14555.1 CAR22093.1 - 0.0077 15.7 1.8 0.021 14.3 1.2 1.8 1 1 0 1 1 1 1 UBA-like domain PTP_N PF12453.3 CAR22093.1 - 0.32 10.6 2.0 0.99 9.0 1.4 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal PTH2 PF01981.11 CAR22094.1 - 3.9e-44 149.0 0.0 7.1e-44 148.2 0.0 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 tRNA-synt_1_2 PF13603.1 CAR22094.1 - 0.05 12.8 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Myc_N PF01056.13 CAR22094.1 - 2.1 7.4 7.6 11 5.0 5.4 1.8 1 1 1 2 2 2 0 Myc amino-terminal region Chorismate_bind PF00425.13 CAR22095.1 - 2.8e-88 295.5 0.0 4.1e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CAR22095.1 - 8.2e-32 110.1 0.0 2.3e-29 102.1 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region POR PF01558.13 CAR22095.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase PP2C PF00481.16 CAR22097.1 - 6e-78 261.7 0.0 8.2e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DASH_Spc34 PF08657.5 CAR22097.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 SpoIIE PF07228.7 CAR22097.1 - 0.1 12.2 0.0 0.65 9.6 0.0 2.1 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) TatD_DNase PF01026.16 CAR22098.1 - 1e-38 133.0 0.0 2e-38 132.0 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase zf-H2C2_2 PF13465.1 CAR22099.1 - 4.1e-06 26.8 2.3 4.1e-06 26.8 1.6 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CAR22099.1 - 7.7e-06 25.9 14.8 0.00072 19.7 0.8 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR22099.1 - 0.00022 21.3 10.9 0.023 14.9 3.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Serglycin PF04360.7 CAR22099.1 - 0.38 10.4 4.8 0.46 10.1 0.1 2.3 2 0 0 2 2 2 0 Serglycin zf-RING-like PF08746.6 CAR22099.1 - 2.7 8.0 7.8 0.28 11.2 2.0 1.9 2 0 0 2 2 2 0 RING-like domain Coprogen_oxidas PF01218.13 CAR22100.1 - 5e-131 435.6 0.0 5.7e-131 435.4 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFIIS_C PF01096.13 CAR22101.1 - 4.4e-22 77.4 1.6 4.4e-22 77.4 1.1 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CAR22101.1 - 9.3e-11 41.2 0.9 6.2e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 CAR22101.1 - 6.6e-05 22.6 4.8 0.08 12.7 0.4 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain C1_1 PF00130.17 CAR22101.1 - 0.018 14.7 2.4 0.043 13.5 0.3 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_5 PF13719.1 CAR22101.1 - 0.088 12.4 5.9 0.68 9.5 0.1 3.4 3 1 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.8 CAR22101.1 - 0.092 12.4 1.1 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 CAR22101.1 - 0.1 12.4 6.1 7.5 6.4 4.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon Desulfoferrod_N PF06397.7 CAR22101.1 - 0.27 10.6 3.1 0.36 10.2 0.1 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF164 PF02591.10 CAR22101.1 - 0.3 10.9 4.0 0.52 10.1 0.0 3.0 4 0 0 4 4 4 0 Putative zinc ribbon domain zf-RING_3 PF14369.1 CAR22101.1 - 0.33 10.9 4.3 2.5 8.1 0.0 3.3 4 0 0 4 4 3 0 zinc-finger DUF2387 PF09526.5 CAR22101.1 - 0.34 10.8 3.5 6.3 6.8 0.1 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Ogr_Delta PF04606.7 CAR22101.1 - 0.4 10.3 5.7 3.2 7.5 0.1 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger IBR PF01485.16 CAR22101.1 - 0.5 10.2 6.3 0.65 9.9 0.1 2.7 2 1 0 2 2 2 0 IBR domain zf-CHY PF05495.7 CAR22101.1 - 0.98 9.6 4.1 0.78 9.9 0.1 2.3 2 1 0 2 2 2 0 CHY zinc finger zf-ribbon_3 PF13248.1 CAR22101.1 - 1.2 8.4 0.0 1.2 8.4 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.1 CAR22101.1 - 1.3 9.3 6.8 3.1 8.1 1.4 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar Terminase_GpA PF05876.7 CAR22101.1 - 2.6 6.3 4.5 7.2 4.8 3.1 1.9 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) PHD PF00628.24 CAR22101.1 - 3.2 7.5 5.6 4.5 7.0 0.2 2.7 2 2 0 2 2 2 0 PHD-finger zinc_ribbon_4 PF13717.1 CAR22101.1 - 5.4 6.8 9.9 8.8 6.1 0.8 3.6 3 1 0 3 3 3 0 zinc-ribbon domain ORC2 PF04084.9 CAR22102.1 - 1.9e-108 362.1 0.2 2.5e-108 361.8 0.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FtsK_SpoIIIE PF01580.13 CAR22102.1 - 0.004 16.6 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ORC6 PF05460.8 CAR22102.1 - 7.4 5.5 13.1 14 4.6 9.1 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.20 CAR22103.1 - 4.6e-37 127.5 0.0 4.6e-37 127.5 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22103.1 - 2e-26 92.6 0.0 2e-26 92.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CAR22103.1 - 0.013 15.1 12.4 0.2 11.3 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family FA_desaturase PF00487.19 CAR22104.1 - 1.1e-21 77.5 23.3 9.9e-21 74.3 16.1 2.0 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CAR22104.1 - 6.1e-19 66.9 1.4 1.3e-18 65.9 1.0 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ECH PF00378.15 CAR22105.1 - 5.1e-25 88.0 0.1 6.7e-24 84.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CAR22105.1 - 1e-19 70.7 0.4 2.7e-19 69.4 0.1 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region UCH PF00443.24 CAR22106.1 - 1.4e-40 139.0 0.1 4.6e-40 137.4 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR22106.1 - 9.3e-23 81.0 0.6 4.8e-22 78.7 0.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CAR22106.1 - 5.9e-22 77.5 14.2 6.8e-22 77.3 3.2 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CAR22106.1 - 6.4e-14 51.2 0.9 2e-07 30.6 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Zn_Tnp_IS91 PF14319.1 CAR22106.1 - 2.3 7.7 8.3 6 6.4 0.1 3.4 3 0 0 3 3 3 0 Transposase zinc-binding domain FlaC_arch PF05377.6 CAR22107.1 - 0.21 11.5 15.7 1.5 8.7 0.1 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DAHP_synth_1 PF00793.15 CAR22108.1 - 1.2e-100 335.7 0.0 1.4e-100 335.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cellulase PF00150.13 CAR22109.1 - 1.8e-09 37.2 4.6 2.7e-09 36.6 3.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PRP1_N PF06424.7 CAR22110.1 - 8.9e-35 119.9 0.2 2.4e-34 118.5 0.2 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CAR22110.1 - 2.5e-20 71.0 11.9 9.5e-05 22.7 0.0 11.2 8 3 4 12 12 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAR22110.1 - 1.7e-18 66.0 5.1 7.4e-05 22.3 0.0 6.6 8 0 0 8 8 8 3 TPR repeat TPR_19 PF14559.1 CAR22110.1 - 1.1e-17 64.1 11.2 0.00079 19.7 0.1 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAR22110.1 - 1.2e-14 54.5 9.1 0.0099 16.5 0.7 8.0 4 2 4 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 CAR22110.1 - 8.2e-12 44.0 13.5 0.055 13.4 0.0 9.9 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAR22110.1 - 1.3e-08 34.6 9.4 0.092 12.6 0.0 6.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CAR22110.1 - 4.7e-05 22.8 1.6 46 4.1 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAR22110.1 - 6.1e-05 22.4 12.8 1.7 8.3 0.0 6.9 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAR22110.1 - 0.00011 22.1 1.2 0.052 13.7 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR22110.1 - 0.00054 20.0 7.0 0.15 12.2 0.1 4.9 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CAR22110.1 - 0.0008 19.7 3.0 12 6.5 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR22110.1 - 0.013 15.2 11.5 18 5.3 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 CAR22110.1 - 0.018 14.8 3.5 3.1 7.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 CAR22110.1 - 0.019 15.6 5.5 0.035 14.7 0.1 3.5 3 0 0 3 3 3 0 Sel1 repeat TPR_21 PF09976.4 CAR22110.1 - 0.029 14.3 0.0 0.029 14.3 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 CAR22110.1 - 0.046 14.2 0.0 0.25 11.8 0.0 2.3 1 0 0 1 1 1 0 HEAT-like repeat Fungal_trans_2 PF11951.3 CAR22111.1 - 4e-21 75.0 0.2 6.8e-21 74.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR22111.1 - 2e-07 30.7 12.5 3.9e-07 29.8 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XkdN PF08890.6 CAR22111.1 - 0.76 9.5 3.3 0.49 10.1 0.4 1.9 2 0 0 2 2 2 0 Phage XkdN-like protein Arginase PF00491.16 CAR22112.1 - 3.8e-86 288.8 0.1 4.8e-86 288.4 0.1 1.1 1 0 0 1 1 1 1 Arginase family MatE PF01554.13 CAR22113.1 - 4.4e-54 182.4 32.6 1.8e-34 118.7 4.7 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 CAR22113.1 - 5.2e-07 29.5 2.9 5.2e-07 29.5 2.0 3.9 2 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain SGL PF08450.7 CAR22114.1 - 1.3e-57 194.9 0.0 1.7e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CAR22114.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase Arylesterase PF01731.15 CAR22114.1 - 0.031 14.2 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 Arylesterase FMN_red PF03358.10 CAR22115.1 - 5.5e-09 35.6 0.0 7.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CAR22115.1 - 5.3e-07 29.7 0.8 2e-06 27.8 0.3 2.2 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.12 CAR22115.1 - 0.00044 19.8 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold CHCH PF06747.8 CAR22116.1 - 4.7e-08 32.7 10.7 0.00038 20.2 1.0 2.3 2 0 0 2 2 2 2 CHCH domain UPF0203 PF05254.7 CAR22116.1 - 1.7e-05 24.5 7.5 0.0085 15.9 0.7 2.7 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) COX6B PF02297.12 CAR22116.1 - 8e-05 22.5 7.7 0.0017 18.3 3.7 2.1 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 CAR22116.1 - 0.00088 19.0 11.3 0.0065 16.2 1.9 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 CAR22116.1 - 0.014 15.3 8.0 0.26 11.2 1.5 2.3 1 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein GCK PF07802.6 CAR22116.1 - 0.029 14.4 7.8 1.1 9.3 0.5 2.6 1 1 2 3 3 3 0 GCK domain Pet191_N PF10203.4 CAR22116.1 - 0.061 13.3 12.0 0.54 10.3 5.1 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DB PF01682.14 CAR22116.1 - 0.24 11.4 9.5 1.2 9.2 6.4 2.0 1 1 0 1 1 1 0 DB module COX17 PF05051.8 CAR22116.1 - 0.65 10.0 8.7 2.1 8.4 0.7 3.0 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) NDUF_B7 PF05676.8 CAR22116.1 - 2.6 7.5 7.1 1.2 8.5 0.6 2.5 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) WD40 PF00400.27 CAR22117.1 - 6.1e-23 79.8 14.0 8.8e-06 25.4 0.4 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CAR22117.1 - 0.00056 18.1 0.7 0.0039 15.4 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Glyco_hydro_100 PF12899.2 CAR22117.1 - 0.099 11.0 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase DUF1752 PF08550.5 CAR22118.1 - 4.2e-11 42.2 1.5 9.8e-11 41.0 1.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF2450 PF10475.4 CAR22119.1 - 5.6e-06 25.4 6.1 9.1e-06 24.7 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF1963 PF09234.5 CAR22120.1 - 2.1e-60 204.7 3.0 2.4e-60 204.5 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) DUF1963 PF09234.5 CAR22121.1 - 3.6e-65 220.3 2.4 3.6e-65 220.3 1.7 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1963) DUF3375 PF11855.3 CAR22123.1 - 0.044 12.5 0.1 0.67 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Myb_DNA-binding PF00249.26 CAR22124.1 - 2.4e-20 72.2 14.5 6.1e-12 45.4 0.4 5.1 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR22124.1 - 4.4e-19 68.3 18.9 1.5e-16 60.2 1.5 4.1 5 0 0 5 5 5 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 CAR22124.1 - 0.051 13.7 11.3 0.31 11.2 1.2 3.8 2 2 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RasGAP PF00616.14 CAR22124.1 - 0.14 11.8 0.4 0.7 9.5 0.7 1.9 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Myb_DNA-bind_4 PF13837.1 CAR22124.1 - 0.69 10.0 19.8 0.12 12.4 4.9 4.2 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain Nop25 PF09805.4 CAR22124.1 - 2.1 8.4 17.2 0.16 12.0 5.9 2.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Med15 PF09606.5 CAR22124.1 - 8.2 4.4 30.3 4 5.5 15.0 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_S17 PF00366.15 CAR22125.1 - 7.5e-31 105.9 4.4 1.2e-30 105.3 3.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 ADH_zinc_N PF00107.21 CAR22127.1 - 2.9e-29 101.2 0.0 4.6e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR22127.1 - 5.4e-16 59.6 0.0 1.3e-15 58.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR22127.1 - 3.2e-09 36.5 0.0 6.2e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain tRNA-synt_2b PF00587.20 CAR22129.1 - 3.3e-34 117.9 0.3 1.1e-33 116.2 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CAR22129.1 - 4.3e-22 78.1 10.5 4.3e-22 78.1 7.3 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain GED PF02212.13 CAR22129.1 - 0.091 12.6 1.5 0.19 11.6 1.0 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain Peptidase_S49_N PF08496.5 CAR22129.1 - 2.3 7.9 6.4 5.5 6.7 4.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Atg31 PF09795.4 CAR22130.1 - 2.9e-26 92.1 2.1 2.7e-25 88.9 1.5 1.9 1 1 0 1 1 1 1 Autophagy-related protein 31 DEAD PF00270.24 CAR22131.1 - 2e-41 141.3 3.1 5.2e-41 139.9 1.4 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR22131.1 - 8.7e-29 99.2 0.2 8.2e-28 96.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CAR22131.1 - 1.1e-05 25.0 0.1 3e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CAR22131.1 - 0.00018 21.6 0.3 0.00073 19.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CAR22131.1 - 0.0027 17.2 0.1 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain tRNA-synt_1b PF00579.20 CAR22131.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ResIII PF04851.10 CAR22131.1 - 0.024 14.4 0.2 0.082 12.7 0.2 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 CAR22131.1 - 0.052 12.6 0.1 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.9 CAR22131.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Helicase Helicase_C_2 PF13307.1 CAR22131.1 - 0.08 12.8 0.1 0.91 9.4 0.0 2.3 1 1 1 2 2 2 0 Helicase C-terminal domain UvrD-helicase PF00580.16 CAR22131.1 - 0.12 11.6 0.2 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PhoH PF02562.11 CAR22131.1 - 0.16 11.1 4.5 0.21 10.7 1.7 2.1 2 1 0 2 2 2 0 PhoH-like protein PRK PF00485.13 CAR22132.1 - 9.3e-10 38.3 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family GCV_T PF01571.16 CAR22134.1 - 1.9e-66 223.4 0.1 2.4e-66 223.0 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CAR22134.1 - 7.8e-14 51.4 0.2 2e-13 50.1 0.1 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CAR22134.1 - 0.00081 19.2 0.0 0.14 11.9 0.0 2.4 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family Lysis_S PF04971.7 CAR22134.1 - 0.048 13.3 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Lysis protein S AA_permease PF00324.16 CAR22135.1 - 2.5e-106 355.9 36.9 2.8e-106 355.7 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR22135.1 - 7.7e-42 143.3 37.5 9.6e-42 142.9 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 CAR22136.1 - 5.3e-38 130.6 22.1 5.3e-38 130.6 15.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.14 CAR22136.1 - 0.057 11.2 0.0 0.13 10.0 0.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF373 PF04123.8 CAR22136.1 - 0.94 8.4 3.8 3.6 6.4 0.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF373) DUF607 PF04678.8 CAR22136.1 - 7.3 6.4 6.1 30 4.4 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF607 Acyltransferase PF01553.16 CAR22137.1 - 4.2e-28 97.4 0.0 7.8e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase AMP-binding PF00501.23 CAR22138.1 - 5.6e-67 225.9 0.0 6.8e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR22138.1 - 0.00053 20.8 0.0 0.0014 19.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acyl_transf_3 PF01757.17 CAR22138.1 - 0.25 10.1 5.7 1.6 7.5 0.7 2.3 2 0 0 2 2 2 0 Acyltransferase family Fig1 PF12351.3 CAR22139.1 - 1.2e-58 198.0 5.8 1.2e-58 198.0 4.0 1.4 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 RDD PF06271.7 CAR22139.1 - 0.46 10.3 0.1 0.46 10.3 0.0 2.8 2 1 0 2 2 2 0 RDD family ATP-synt PF00231.14 CAR22140.1 - 2.4e-69 233.8 3.5 2.7e-69 233.7 2.4 1.0 1 0 0 1 1 1 1 ATP synthase IPK PF03770.11 CAR22141.1 - 4.4e-51 173.3 0.0 1.1e-50 172.0 0.0 1.7 1 0 0 1 1 1 1 Inositol polyphosphate kinase DASH_Dad1 PF08649.5 CAR22142.1 - 7.2e-30 102.4 1.2 9.2e-30 102.1 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Sec34 PF04136.10 CAR22142.1 - 0.13 11.9 0.1 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Sec34-like family PNPOx_C PF10590.4 CAR22144.1 - 2.1e-19 68.7 0.9 5.4e-19 67.4 0.6 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 CAR22144.1 - 3.3e-15 55.8 0.0 4.9e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sld5 PF05916.6 CAR22146.1 - 4.5e-14 52.6 0.5 6.6e-14 52.1 0.4 1.3 1 0 0 1 1 1 1 GINS complex protein PIF1 PF05970.9 CAR22146.1 - 0.024 13.5 0.2 0.039 12.9 0.0 1.4 2 0 0 2 2 2 0 PIF1-like helicase SSV1_ORF_D-335 PF07935.6 CAR22147.1 - 0.07 12.8 0.7 0.21 11.3 0.5 1.8 1 0 0 1 1 1 0 ORF D-335-like protein UMP1 PF05348.6 CAR22147.1 - 0.098 12.6 0.1 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 Spore_YhaL PF14147.1 CAR22147.1 - 1.5 8.3 5.9 2.3 7.7 4.1 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL PRP38 PF03371.10 CAR22148.1 - 2e-48 164.2 0.3 2.6e-48 163.9 0.2 1.0 1 0 0 1 1 1 1 PRP38 family LSM PF01423.17 CAR22149.1 - 4.9e-19 67.6 0.2 4.9e-19 67.6 0.1 1.6 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 CAR22149.1 - 4.7e-05 23.2 0.1 7e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Mpv17_PMP22 PF04117.7 CAR22150.1 - 0.023 14.3 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Mpv17 / PMP22 family DUF4281 PF14108.1 CAR22150.1 - 0.026 14.6 0.3 0.072 13.1 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) UNC-93 PF05978.11 CAR22150.1 - 0.032 13.7 0.3 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PulG PF11773.3 CAR22150.1 - 1.8 8.3 4.3 13 5.6 0.1 2.9 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin Smg4_UPF3 PF03467.10 CAR22151.1 - 1.1e-25 90.6 6.6 1.1e-25 90.6 4.6 2.4 1 1 2 3 3 3 1 Smg-4/UPF3 family PCI PF01399.22 CAR22152.1 - 3.8e-09 36.8 1.5 1.8e-08 34.6 0.0 2.7 3 1 0 3 3 3 1 PCI domain Metallophos PF00149.23 CAR22153.1 - 4.5e-43 146.9 0.2 5.6e-43 146.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DIL PF01843.14 CAR22153.1 - 0.087 12.7 0.1 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 DIL domain E1_DerP2_DerF2 PF02221.10 CAR22154.1 - 3e-29 101.9 0.1 3.4e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CAR22154.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.5 1 1 0 1 1 1 1 ML-like domain Y_Y_Y PF07495.8 CAR22154.1 - 0.14 11.8 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Y_Y_Y domain DIM PF08194.7 CAR22154.1 - 0.3 11.0 2.9 0.75 9.8 2.0 1.6 1 0 0 1 1 1 0 DIM protein Sdh5 PF03937.11 CAR22155.1 - 5e-25 86.9 0.6 7.8e-25 86.3 0.4 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase CHCH PF06747.8 CAR22156.1 - 4.4e-06 26.4 0.4 6.1e-06 26.0 0.3 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CAR22156.1 - 0.027 14.2 0.4 0.037 13.7 0.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CMV_US PF08001.6 CAR22156.1 - 0.059 12.4 0.1 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 CMV US PAPS_reduct PF01507.14 CAR22157.1 - 1.4e-30 106.4 0.0 2e-29 102.6 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF445 PF04286.7 CAR22158.1 - 0.028 13.9 2.6 0.084 12.3 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF272 PF03312.10 CAR22158.1 - 0.046 13.9 0.0 0.2 11.8 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF272) DUF310 PF03750.8 CAR22158.1 - 0.33 11.1 4.3 25 5.0 0.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF310) Myb_DNA-bind_3 PF12776.2 CAR22159.1 - 0.32 11.6 4.1 15 6.2 0.3 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain FMO-like PF00743.14 CAR22160.1 - 3.5e-12 45.2 1.2 1.6e-05 23.3 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CAR22160.1 - 3.6e-06 27.2 0.0 0.064 13.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR22160.1 - 1.1e-05 25.2 0.0 0.00044 20.0 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CAR22160.1 - 0.00011 22.1 0.0 0.00042 20.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CAR22160.1 - 0.0016 18.3 0.0 0.035 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAR22160.1 - 0.024 13.1 0.0 0.032 12.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 CAR22160.1 - 0.046 12.6 0.0 0.52 9.1 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 CAR22160.1 - 0.049 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Nuf2 PF03800.9 CAR22161.1 - 6.7e-49 165.6 0.3 6.7e-49 165.6 0.2 2.7 2 1 1 3 3 3 1 Nuf2 family DUF3627 PF12299.3 CAR22161.1 - 0.032 14.2 0.2 0.12 12.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) DUF1599 PF07659.6 CAR22161.1 - 0.096 12.7 0.9 0.49 10.4 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1599) EFG_C PF00679.19 CAR22161.1 - 0.12 12.2 0.7 24 4.8 0.0 3.5 3 0 0 3 3 3 0 Elongation factor G C-terminus MscS_porin PF12795.2 CAR22161.1 - 0.69 9.1 41.8 0.51 9.6 24.8 3.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Endonuc-BglII PF09195.6 CAR22161.1 - 0.92 8.9 5.5 7.6 5.9 3.8 2.4 1 1 0 1 1 1 0 Restriction endonuclease BglII SlyX PF04102.7 CAR22161.1 - 4.7 7.6 18.7 0.96 9.8 0.3 4.7 5 0 0 5 5 5 0 SlyX zf-met PF12874.2 CAR22162.1 - 3.7e-06 26.9 1.1 8.9e-06 25.7 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CAR22162.1 - 0.041 13.9 0.1 0.082 13.0 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF3505 PF12013.3 CAR22162.1 - 0.043 14.0 0.1 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) PASTA PF03793.14 CAR22162.1 - 0.11 12.2 0.0 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 PASTA domain Nudix_N_2 PF14803.1 CAR22162.1 - 0.13 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Nudix N-terminal SIR2 PF02146.12 CAR22163.1 - 1.3e-66 223.6 0.0 2.1e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 CAR22163.1 - 7.2e-62 207.4 0.3 1.2e-61 206.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 CAR22163.1 - 0.0045 16.7 0.0 1.7 8.4 0.0 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain DUF327 PF03885.8 CAR22163.1 - 0.046 13.5 0.6 0.52 10.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF327) HLH PF00010.21 CAR22164.1 - 1.1e-15 57.0 0.0 1.7e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DnaB_bind PF10410.4 CAR22164.1 - 0.066 13.2 0.2 7.6 6.6 0.0 2.9 2 1 0 2 2 2 0 DnaB-helicase binding domain of primase NARP1 PF12569.3 CAR22165.1 - 3.8e-115 385.5 24.7 1.2e-84 284.9 2.9 3.9 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 CAR22165.1 - 1.2e-14 52.9 10.1 0.034 14.0 0.1 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAR22165.1 - 1.8e-11 44.3 11.5 0.00068 20.2 0.1 5.9 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAR22165.1 - 5.5e-11 42.0 0.7 0.53 11.0 0.0 7.0 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR22165.1 - 1.4e-09 38.1 11.0 0.17 12.2 0.0 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAR22165.1 - 4.7e-07 29.3 21.6 0.062 12.9 0.5 5.1 5 0 0 5 5 5 3 TPR repeat TPR_12 PF13424.1 CAR22165.1 - 0.00014 21.7 16.6 0.27 11.2 0.3 5.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAR22165.1 - 0.0011 18.5 9.8 3.5 7.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAR22165.1 - 0.015 15.4 9.1 30 5.1 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR22165.1 - 0.02 15.3 0.9 2.8 8.6 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAR22165.1 - 0.044 13.7 0.0 42 4.2 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR22165.1 - 0.2 11.5 5.3 4.5 7.2 0.1 3.4 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat DUF4463 PF14703.1 CAR22165.1 - 0.23 12.0 6.4 1.9 9.0 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) PseudoU_synth_2 PF00849.17 CAR22166.1 - 3.3e-32 111.5 0.0 6e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 CAR22166.1 - 2.2e-17 62.5 0.0 5.4e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Exo_endo_phos PF03372.18 CAR22167.1 - 1.6e-14 54.4 0.0 2.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CAR22167.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Git3 PF11710.3 CAR22168.1 - 1.2e-75 253.5 10.5 2.2e-75 252.6 7.3 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 CAR22168.1 - 2.2e-32 110.6 4.3 2.2e-32 110.6 3.0 2.7 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term SPC12 PF06645.8 CAR22168.1 - 0.17 11.6 3.5 3.4 7.5 0.1 2.8 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Inositol_P PF00459.20 CAR22169.1 - 7.5e-53 179.5 0.1 1.8e-52 178.2 0.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family tRNA_Me_trans PF03054.11 CAR22170.1 - 7.6e-108 360.2 0.0 8.7e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 CAR22170.1 - 0.0018 17.8 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 CAR22170.1 - 0.021 13.7 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 NAD synthase KRE9 PF05390.6 CAR22170.1 - 0.092 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 DEAD PF00270.24 CAR22171.1 - 1.2e-45 155.0 0.1 6e-44 149.5 0.0 2.8 2 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR22171.1 - 6.7e-21 73.9 0.0 2.3e-20 72.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CAR22171.1 - 8.4e-21 73.5 5.1 3.1e-20 71.7 3.5 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DUF3449 PF11931.3 CAR22172.1 - 1.8e-68 229.9 0.1 4.2e-68 228.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-met PF12874.2 CAR22172.1 - 6.3e-09 35.7 0.1 0.00013 21.9 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR22172.1 - 2.5e-08 33.8 0.8 4.4e-06 26.6 0.0 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CAR22172.1 - 0.013 15.5 0.1 0.89 9.7 0.1 3.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CAR22172.1 - 0.74 10.2 3.9 8.4 6.9 0.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger CTP_transf_1 PF01148.15 CAR22173.1 - 1.4e-79 267.3 22.8 1.9e-79 266.9 15.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2370 PF10176.4 CAR22173.1 - 0.19 11.0 1.7 0.91 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Pkinase PF00069.20 CAR22174.1 - 2.8e-62 210.2 0.0 4.4e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22174.1 - 9.9e-32 110.0 0.0 1.1e-30 106.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CAR22174.1 - 5.5e-05 23.6 0.1 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR22174.1 - 0.016 14.2 0.0 0.035 13.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like DUF3775 PF12616.3 CAR22175.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Mannosyl_trans3 PF11051.3 CAR22176.1 - 7.7e-68 228.7 0.0 1.1e-67 228.2 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative RTP801_C PF07809.6 CAR22176.1 - 0.08 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region NMO PF03060.10 CAR22177.1 - 1.8e-38 132.5 7.9 2.4e-36 125.5 5.5 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CAR22177.1 - 4.2e-05 22.6 0.5 0.0088 14.9 0.4 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CAR22177.1 - 4.4e-05 22.5 8.2 0.00012 21.0 5.7 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 CAR22177.1 - 0.1 11.5 2.9 0.27 10.1 2.1 1.6 1 1 0 1 1 1 0 Conserved region in glutamate synthase ADH_zinc_N PF00107.21 CAR22178.1 - 3.2e-05 23.4 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR22178.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CAR22178.1 - 0.032 15.1 0.0 0.11 13.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HLH PF00010.21 CAR22180.1 - 1.7e-05 24.3 0.1 3.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain OCC1 PF15506.1 CAR22180.1 - 0.046 13.6 1.2 0.077 12.8 0.8 1.5 1 0 0 1 1 1 0 OCC1 family DUF1751 PF08551.5 CAR22181.1 - 2.5e-27 95.1 0.9 2.5e-27 95.1 0.6 2.4 2 1 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 CAR22181.1 - 0.00074 19.5 3.9 0.00074 19.5 2.7 1.6 2 0 0 2 2 2 1 Rhomboid family DUF2678 PF10856.3 CAR22181.1 - 5.7 6.6 9.2 1 9.1 3.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) Ribosomal_L18e PF00828.14 CAR22182.1 - 4e-22 78.9 3.3 4.5e-22 78.8 0.4 2.1 2 1 0 2 2 2 1 Ribosomal protein L18e/L15 WSC PF01822.14 CAR22183.1 - 7e-12 45.1 13.9 7e-12 45.1 9.6 3.6 2 1 1 3 3 3 1 WSC domain DUF605 PF04652.11 CAR22183.1 - 0.00025 20.5 31.7 0.00025 20.5 22.0 1.4 2 0 0 2 2 2 1 Vta1 like DUF4448 PF14610.1 CAR22183.1 - 0.0072 15.8 0.8 0.0072 15.8 0.6 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) TFIIA PF03153.8 CAR22183.1 - 0.022 14.6 16.0 0.034 14.0 11.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR19-TM PF15176.1 CAR22183.1 - 0.026 14.2 0.0 0.026 14.2 0.0 3.0 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF1275 PF06912.6 CAR22183.1 - 0.057 12.6 2.9 0.13 11.3 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF4328 PF14219.1 CAR22183.1 - 0.08 12.2 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Syndecan PF01034.15 CAR22183.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain ABC_membrane PF00664.18 CAR22184.1 - 2.1e-59 201.2 37.9 3.3e-36 125.1 6.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAR22184.1 - 1.1e-47 161.7 0.1 2.7e-30 105.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAR22184.1 - 2.9e-10 40.6 1.3 0.0082 16.1 0.0 5.0 4 1 0 4 4 3 2 AAA domain SMC_N PF02463.14 CAR22184.1 - 7.3e-10 38.4 6.3 0.0028 16.8 1.6 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 CAR22184.1 - 1.9e-07 31.0 0.1 0.0028 17.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 CAR22184.1 - 1.3e-06 27.8 0.1 0.041 13.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CAR22184.1 - 2.2e-06 27.7 0.6 0.032 14.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CAR22184.1 - 4.9e-05 24.1 0.0 0.49 11.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAR22184.1 - 0.00011 21.3 0.0 0.042 13.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CAR22184.1 - 0.00017 21.1 0.4 0.33 10.3 0.0 3.3 2 1 1 3 3 3 1 AAA-like domain AAA_25 PF13481.1 CAR22184.1 - 0.00023 20.6 0.0 0.61 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CAR22184.1 - 0.00049 19.9 0.4 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 CAR22184.1 - 0.00099 18.0 0.0 0.35 9.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 CAR22184.1 - 0.0013 18.6 0.3 0.062 13.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 CAR22184.1 - 0.0013 18.3 0.1 8.9 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 CAR22184.1 - 0.0014 18.4 1.9 0.021 14.6 0.0 3.0 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 CAR22184.1 - 0.0017 18.8 0.1 0.81 10.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CAR22184.1 - 0.0023 17.4 0.0 0.69 9.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 CAR22184.1 - 0.0024 17.9 2.8 1.3 9.1 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CAR22184.1 - 0.0047 17.2 3.8 3.8 7.8 0.0 3.4 3 1 0 3 3 2 2 AAA domain GTP_EFTU PF00009.22 CAR22184.1 - 0.0049 16.3 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 CAR22184.1 - 0.0068 15.2 0.0 1 8.0 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 CAR22184.1 - 0.01 16.1 0.0 1.8 8.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CAR22184.1 - 0.013 14.3 1.3 0.89 8.3 0.0 3.3 4 0 0 4 4 4 0 NB-ARC domain Zeta_toxin PF06414.7 CAR22184.1 - 0.019 14.1 0.1 3.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 CAR22184.1 - 0.033 13.9 0.6 8.7 6.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cIII PF08134.6 CAR22184.1 - 0.046 13.3 0.0 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 cIII protein family NACHT PF05729.7 CAR22184.1 - 0.12 12.0 1.2 0.99 9.0 0.0 2.7 3 0 0 3 3 2 0 NACHT domain ATP-synt_ab PF00006.20 CAR22184.1 - 0.12 11.8 0.4 19 4.6 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain RNase_P_pop3 PF08228.6 CAR22185.1 - 4.7e-44 150.0 0.0 5.9e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 RNase P subunit Pop3 Aha1_N PF09229.6 CAR22186.1 - 4.4e-30 104.2 0.0 5.3e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Phage_T7_tail PF03906.9 CAR22186.1 - 0.0065 16.1 0.0 0.0078 15.8 0.0 1.1 1 0 0 1 1 1 1 Phage T7 tail fibre protein ERG4_ERG24 PF01222.12 CAR22187.1 - 1e-165 551.5 10.8 1.1e-165 551.3 7.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CAR22187.1 - 9.3e-05 21.8 0.2 0.00017 20.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Sec20 PF03908.8 CAR22189.1 - 6.4e-24 83.4 0.7 6.4e-24 83.4 0.5 1.9 2 0 0 2 2 2 1 Sec20 Phage_Coat_Gp8 PF05371.7 CAR22189.1 - 8.4 6.0 8.6 1.9 8.1 1.3 2.6 3 0 0 3 3 3 0 Phage major coat protein, Gp8 Sugar_tr PF00083.19 CAR22190.1 - 7.4e-139 463.1 27.3 9e-139 462.9 18.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR22190.1 - 3e-30 105.1 34.0 1.1e-29 103.3 16.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR22190.1 - 3.7e-05 22.1 4.1 3.7e-05 22.1 2.8 1.9 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CAR22190.1 - 0.0029 15.8 0.5 0.0054 14.9 0.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector CPL PF08144.6 CAR22191.1 - 8.4e-20 71.1 0.1 7.2e-18 64.8 0.0 3.2 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.14 CAR22191.1 - 0.00015 21.0 1.8 15 5.3 0.0 5.6 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DUF4253 PF14062.1 CAR22191.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Daxx PF03344.10 CAR22191.1 - 0.15 10.4 16.0 0.25 9.7 11.1 1.2 1 0 0 1 1 1 0 Daxx Family DTHCT PF08070.6 CAR22193.1 - 7.5 7.2 11.6 19 5.9 1.2 3.3 1 1 0 2 2 2 0 DTHCT (NUC029) region PTS_2-RNA PF01885.11 CAR22194.1 - 1.1e-53 181.2 0.0 1.5e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 CAR22194.1 - 0.00033 20.4 0.0 0.00062 19.5 0.0 1.5 1 0 0 1 1 1 1 La domain S-antigen PF05756.6 CAR22195.1 - 0.043 13.8 0.3 0.21 11.6 0.1 1.8 1 1 0 2 2 2 0 S-antigen protein HlyIII PF03006.15 CAR22196.1 - 4.7e-53 179.8 22.1 5.5e-53 179.6 15.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related CopD PF05425.8 CAR22196.1 - 1.5 9.0 4.9 1.1 9.5 0.2 2.7 2 1 1 3 3 3 0 Copper resistance protein D DUF4003 PF13170.1 CAR22197.1 - 0.08 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Pkinase PF00069.20 CAR22198.1 - 1.2e-64 218.0 0.2 2.1e-64 217.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22198.1 - 1.2e-35 122.8 0.0 1.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR22198.1 - 4.9e-09 35.5 0.0 9.3e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR22198.1 - 0.00081 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR22198.1 - 0.038 13.7 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M16_C PF05193.16 CAR22199.1 - 3.9e-17 62.5 0.0 5.1e-14 52.3 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CAR22199.1 - 3.3e-09 36.6 0.0 1.3e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) SKI PF01202.17 CAR22199.1 - 0.062 13.1 0.5 0.23 11.3 0.1 2.1 3 0 0 3 3 3 0 Shikimate kinase Sld5 PF05916.6 CAR22200.1 - 1.4e-13 51.1 0.2 2.4e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein WD40 PF00400.27 CAR22201.1 - 0.044 13.6 2.3 3.4 7.6 0.0 3.9 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF1091 PF06477.8 CAR22203.1 - 0.0046 17.3 0.0 0.0059 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1091) DHBP_synthase PF00926.14 CAR22204.1 - 3.8e-77 257.9 0.1 4.3e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase tRNA-synt_1b PF00579.20 CAR22205.1 - 5e-19 68.5 0.0 2e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Snf7 PF03357.16 CAR22206.1 - 1.4e-37 128.6 15.8 1.7e-37 128.4 10.9 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 CAR22206.1 - 0.011 15.7 8.7 0.011 15.7 6.0 2.1 1 1 1 2 2 2 0 YlqD protein Fmp27_WPPW PF10359.4 CAR22206.1 - 0.013 13.9 5.8 0.018 13.4 4.0 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain BLOC1_2 PF10046.4 CAR22206.1 - 0.019 15.0 15.9 0.057 13.5 1.7 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 CAR22206.1 - 0.027 14.3 11.4 0.034 13.9 6.7 2.0 1 1 1 2 2 2 0 Tropomyosin like DUF1411 PF07199.6 CAR22206.1 - 0.051 13.0 3.1 0.089 12.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) UPF0242 PF06785.6 CAR22206.1 - 0.067 11.8 4.4 0.086 11.5 3.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Mnd1 PF03962.10 CAR22206.1 - 0.11 12.1 11.6 0.082 12.5 3.3 2.1 1 1 1 2 2 2 0 Mnd1 family Peptidase_S46 PF10459.4 CAR22206.1 - 0.15 10.4 10.1 0.18 10.2 7.0 1.0 1 0 0 1 1 1 0 Peptidase S46 GTPase_Cys_C PF12631.2 CAR22206.1 - 0.56 10.6 2.5 4.6 7.7 0.1 2.8 2 1 1 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Reo_sigmaC PF04582.7 CAR22206.1 - 0.74 8.9 6.8 1.5 7.8 4.6 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 CAR22206.1 - 0.81 6.9 18.2 1.1 6.5 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 CAR22206.1 - 0.93 8.3 13.1 1.4 7.7 9.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Exonuc_VII_L PF02601.10 CAR22206.1 - 1.1 8.3 11.7 1.3 8.0 8.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.6 CAR22206.1 - 1.4 8.7 9.0 0.55 10.1 1.8 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HAUS-augmin3 PF14932.1 CAR22206.1 - 2.3 7.3 17.3 2.7 7.0 2.9 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 CAR22206.1 - 3 5.5 6.7 4.6 4.9 4.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 CAR22206.1 - 3.8 7.9 10.7 1.2 9.5 1.8 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Prefoldin PF02996.12 CAR22206.1 - 3.9 7.1 13.5 0.3 10.7 1.6 3.3 2 1 2 4 4 4 0 Prefoldin subunit Serine_rich PF08824.5 CAR22206.1 - 6 6.5 11.8 5.2 6.7 5.8 2.4 1 1 1 2 2 2 0 Serine rich protein interaction domain IncA PF04156.9 CAR22206.1 - 8 6.0 16.6 2.9e+02 0.9 11.5 2.2 1 1 0 1 1 1 0 IncA protein ACR_tran PF00873.14 CAR22206.1 - 8.3 3.6 9.9 10 3.3 6.8 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Methyltransf_23 PF13489.1 CAR22207.1 - 5.2e-23 81.5 0.0 7.5e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR22207.1 - 9.2e-17 61.0 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR22207.1 - 5.7e-15 55.8 0.0 1.2e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR22207.1 - 2.3e-14 53.6 0.0 4.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR22207.1 - 1.7e-12 47.6 0.0 3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAR22207.1 - 3.3e-08 32.9 0.0 4.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CAR22207.1 - 1.1e-07 32.0 0.0 2.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAR22207.1 - 8.6e-07 28.3 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CAR22207.1 - 1.2e-06 27.9 0.0 2.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CAR22207.1 - 1.7e-06 28.0 0.0 1.1e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 CAR22207.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.7 CAR22207.1 - 2.9e-05 23.0 0.0 5.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.7 CAR22207.1 - 0.00028 20.3 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 CAR22207.1 - 0.00048 18.9 0.0 0.0007 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 CAR22207.1 - 0.00062 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR22207.1 - 0.0053 15.9 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CAR22207.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 CAR22207.1 - 0.0094 15.2 0.0 1.2 8.3 0.0 2.5 2 1 0 3 3 3 1 CheR methyltransferase, SAM binding domain TehB PF03848.9 CAR22207.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Spermine_synth PF01564.12 CAR22207.1 - 0.024 13.5 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase Methyltransf_4 PF02390.12 CAR22207.1 - 0.055 12.5 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.15 CAR22207.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase YL1 PF05764.8 CAR22208.1 - 1.4e-52 178.7 39.3 1.4e-52 178.7 27.2 3.6 2 1 1 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 CAR22208.1 - 4.6e-12 45.2 0.6 7.6e-12 44.5 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain UvrD_C PF13361.1 CAR22209.1 - 3.1e-47 161.7 0.0 1.3e-46 159.6 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CAR22209.1 - 3.5e-30 105.3 0.3 9.3e-14 51.4 0.0 2.9 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 CAR22209.1 - 2.4e-12 46.8 0.0 0.00011 21.7 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CAR22209.1 - 5.3e-12 45.7 0.0 2.4e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CAR22209.1 - 4.7e-08 32.6 0.1 6.6e-07 28.9 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 CAR22209.1 - 1.7e-06 27.7 0.1 0.00055 19.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.1 CAR22209.1 - 8.3e-05 22.0 0.1 0.07 12.5 0.0 3.8 2 1 0 3 3 3 1 AAA domain DEAD PF00270.24 CAR22209.1 - 0.00041 19.8 0.1 0.002 17.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR22209.1 - 0.0025 17.9 0.0 0.88 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 CAR22209.1 - 0.027 14.1 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Helicase Cullin_Nedd8 PF10557.4 CAR22209.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Cullin protein neddylation domain Vps52 PF04129.7 CAR22210.1 - 2.2e-130 435.6 14.1 2.9e-130 435.1 9.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family DUF3552 PF12072.3 CAR22210.1 - 0.024 13.8 0.3 0.051 12.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Rep_fac_C PF08542.6 CAR22211.1 - 7.3e-19 67.5 0.1 2.2e-18 65.9 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CAR22211.1 - 8.9e-13 48.2 0.1 1.1e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CAR22211.1 - 1.1e-12 48.2 0.0 2.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CAR22211.1 - 5.8e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR22211.1 - 1.1e-06 28.7 0.1 2.1e-05 24.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 CAR22211.1 - 2.4e-06 26.5 0.0 0.00083 18.1 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 CAR22211.1 - 2.8e-06 26.9 0.0 7e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR22211.1 - 1.9e-05 24.7 0.3 0.003 17.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR22211.1 - 3.4e-05 23.0 0.1 0.00013 21.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 CAR22211.1 - 8e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 CAR22211.1 - 0.00016 21.2 0.1 0.0003 20.3 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 CAR22211.1 - 0.00034 19.8 0.0 0.0037 16.4 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 CAR22211.1 - 0.00046 19.7 0.1 0.27 10.6 0.0 2.6 1 1 1 3 3 3 2 AAA-like domain ArgK PF03308.11 CAR22211.1 - 0.0045 15.7 0.1 0.03 13.0 0.0 2.1 1 1 1 2 2 2 1 ArgK protein KTI12 PF08433.5 CAR22211.1 - 0.0048 16.1 0.0 0.0085 15.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 CAR22211.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 CAR22211.1 - 0.024 14.3 0.1 0.19 11.4 0.1 2.2 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.1 CAR22211.1 - 0.027 14.1 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 CAR22211.1 - 0.03 13.9 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CAR22211.1 - 0.032 13.6 0.0 0.068 12.6 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.24 CAR22211.1 - 0.063 12.7 0.1 0.84 9.1 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.1 CAR22211.1 - 0.064 12.6 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain tRNA_m1G_MT PF01746.16 CAR22212.1 - 2.7e-33 115.1 0.5 5e-33 114.2 0.1 1.7 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase PQ-loop PF04193.9 CAR22213.1 - 7.6e-39 131.0 18.5 5.3e-21 73.9 2.1 2.9 3 0 0 3 3 3 2 PQ loop repeat DegS PF05384.6 CAR22214.1 - 0.001 18.2 23.4 0.049 12.8 8.8 2.8 1 1 0 2 2 2 2 Sensor protein DegS BLOC1_2 PF10046.4 CAR22214.1 - 0.26 11.4 13.7 0.038 14.1 3.6 3.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 CAR22214.1 - 7.1 6.6 12.5 3.4 7.6 0.7 3.8 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) MutS_V PF00488.16 CAR22215.1 - 1.8e-96 322.0 0.2 3.1e-96 321.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR22215.1 - 9e-35 120.3 0.1 9e-35 120.3 0.1 2.3 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.12 CAR22215.1 - 1.7e-20 73.5 0.1 6.1e-20 71.6 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CAR22215.1 - 5.8e-16 58.4 0.3 1.3e-15 57.3 0.2 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 CAR22215.1 - 1.3e-09 38.0 0.0 4.8e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain I Aldo_ket_red PF00248.16 CAR22216.1 - 1.2e-46 158.8 0.0 1.5e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 CAR22217.1 - 2.5e-16 59.3 0.9 5.6e-16 58.1 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR22217.1 - 8.5e-09 35.1 10.2 1.9e-08 34.0 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.7 CAR22218.1 - 4.2e-57 193.8 0.0 5.3e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-PARP PF00645.13 CAR22218.1 - 0.042 14.0 1.8 0.11 12.7 1.2 1.7 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Thioredoxin PF00085.15 CAR22219.1 - 1.2e-11 44.1 0.0 2.8e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAR22219.1 - 0.00082 19.4 0.4 0.0035 17.4 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CAR22219.1 - 0.022 14.9 0.3 0.098 12.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Glyco_hydro_92 PF07971.7 CAR22219.1 - 0.12 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 AhpC-TSA PF00578.16 CAR22219.1 - 0.13 11.9 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Zn_clus PF00172.13 CAR22220.1 - 1.5e-08 34.3 8.3 2.9e-08 33.4 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CAR22220.1 - 8.3e-05 21.5 1.0 0.00024 20.0 0.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 CAR22221.1 - 6.6e-39 133.6 48.0 1.7e-29 102.6 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CAR22221.1 - 3.4e-11 42.0 14.8 3.4e-11 42.0 10.2 2.8 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 CAR22222.1 - 8.8e-31 106.8 60.9 4.6e-29 101.2 23.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldolase_II PF00596.16 CAR22223.1 - 9.2e-49 165.5 0.1 1.2e-48 165.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NUDIX PF00293.23 CAR22224.1 - 3.9e-18 65.3 0.3 4.8e-18 65.0 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain DUF3225 PF11533.3 CAR22224.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) DUF410 PF04190.8 CAR22225.1 - 2.3e-72 243.6 0.1 2.6e-72 243.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_11 PF13414.1 CAR22225.1 - 0.079 12.6 0.3 0.26 10.9 0.2 1.9 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 CAR22225.1 - 0.12 13.1 3.2 16 6.3 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat RHD3 PF05879.7 CAR22226.1 - 7.5e-244 811.0 15.9 9.1e-244 810.7 11.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 CAR22226.1 - 6.7e-06 26.0 0.1 3e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CAR22226.1 - 0.00011 22.1 0.0 0.00055 19.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CAR22226.1 - 0.0009 19.7 0.0 0.0027 18.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 CAR22226.1 - 0.003 16.6 0.1 0.028 13.4 0.0 2.3 2 0 0 2 2 2 1 Septin AAA_28 PF13521.1 CAR22226.1 - 0.059 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CAR22226.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain XLF PF09302.6 CAR22227.1 - 0.0089 15.8 0.2 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) PIN_4 PF13638.1 CAR22228.1 - 4.7e-32 110.8 0.1 8.6e-32 110.0 0.1 1.5 1 0 0 1 1 1 1 PIN domain Adenosine_kin PF04008.9 CAR22228.1 - 0.097 12.1 0.1 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Adenosine specific kinase Ribosomal_S28e PF01200.13 CAR22229.1 - 7.4e-34 115.3 2.9 8e-34 115.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.7 CAR22229.1 - 0.14 11.8 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Red1 PF07964.6 CAR22230.1 - 1.2e-80 271.6 8.7 3e-46 157.9 2.6 2.6 1 1 1 2 2 2 2 Rec10 / Red1 tRNA-synt_1c PF00749.16 CAR22231.1 - 1.4e-113 378.7 0.0 1.9e-113 378.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CAR22231.1 - 5.8e-55 185.2 0.2 9.4e-55 184.5 0.1 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CAR22231.1 - 3.4e-35 121.2 0.2 9.6e-34 116.5 0.1 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CAR22231.1 - 2.1e-22 79.6 2.4 6e-22 78.1 1.6 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Peptidase_C28 PF05408.6 CAR22231.1 - 0.057 12.8 0.1 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase TMA7 PF09072.5 CAR22232.1 - 9.2e-23 80.4 17.3 1e-22 80.3 12.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Ras PF00071.17 CAR22233.1 - 1.1e-56 190.7 0.8 1.4e-56 190.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR22233.1 - 2.3e-22 79.6 0.1 4.7e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR22233.1 - 2.7e-16 59.3 0.5 3.6e-16 58.9 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR22233.1 - 5.8e-06 25.6 0.3 7.8e-06 25.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR22233.1 - 7.2e-06 25.3 0.0 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CAR22233.1 - 8e-06 25.4 0.1 3.6e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR22233.1 - 8.3e-06 25.7 0.0 1.6e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CAR22233.1 - 0.00022 20.9 0.2 0.0007 19.3 0.0 1.7 1 1 1 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 CAR22233.1 - 0.003 17.6 0.0 0.015 15.3 0.0 1.9 1 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAR22233.1 - 0.0065 15.6 0.1 0.019 14.1 0.0 1.6 1 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 CAR22233.1 - 0.02 14.4 0.1 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAR22233.1 - 0.025 14.5 0.0 0.053 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 CAR22233.1 - 0.031 13.7 0.2 0.065 12.7 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CAR22233.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DAGK_cat PF00781.19 CAR22234.1 - 2.6e-27 94.7 0.0 5.2e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cpn60_TCP1 PF00118.19 CAR22235.1 - 1.9e-115 386.2 8.9 2.2e-115 386.0 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family cobW PF02492.14 CAR22236.1 - 1.4e-44 151.6 6.9 1.7e-42 144.9 4.8 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CAR22236.1 - 1.5e-19 69.4 0.0 1.4e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain YlbD_coat PF14071.1 CAR22236.1 - 0.0011 19.0 3.4 0.0011 19.0 2.3 2.6 3 1 0 3 3 2 1 Putative coat protein T2SE PF00437.15 CAR22236.1 - 0.0081 15.0 0.1 0.017 14.0 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CAR22236.1 - 0.028 14.5 0.1 0.078 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CAR22236.1 - 0.039 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 CAR22236.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 CAR22236.1 - 0.066 12.7 0.3 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CAR22236.1 - 0.093 12.6 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CAR22236.1 - 0.13 12.5 0.1 0.13 12.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Spore_coat_CotO PF14153.1 CAR22236.1 - 1.3 8.4 18.8 0.67 9.3 4.7 2.5 2 0 0 2 2 2 0 Spore coat protein CotO CDC45 PF02724.9 CAR22236.1 - 1.9 6.3 18.4 0.13 10.2 4.1 2.1 2 0 0 2 2 2 0 CDC45-like protein Fungal_trans PF04082.13 CAR22238.1 - 6.2e-18 64.6 0.0 9.6e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR22238.1 - 4.7e-09 36.0 8.1 4.7e-09 36.0 5.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 CAR22239.1 - 1.7e-15 56.6 0.3 6.9e-14 51.5 0.2 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR22239.1 - 1.6e-12 48.4 0.0 2.8e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CAR22239.1 - 0.00035 20.6 0.3 0.00057 19.9 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CAR22239.1 - 0.0081 15.6 0.1 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CAR22239.1 - 0.029 13.6 0.2 0.043 13.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.15 CAR22239.1 - 0.049 13.5 1.9 0.066 13.1 0.2 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 CAR22240.1 - 6.8e-45 153.3 51.1 1.3e-44 152.3 34.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily RNA_pol_I_TF PF04090.7 CAR22241.1 - 2.6e-62 209.6 0.0 4.6e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor zf-RING_2 PF13639.1 CAR22242.1 - 1.8e-11 43.6 9.1 1.8e-11 43.6 6.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CAR22242.1 - 1.7e-08 34.4 6.4 3.5e-08 33.4 4.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CAR22242.1 - 2e-07 30.5 7.8 4e-07 29.6 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR22242.1 - 0.0001 21.9 7.6 0.00023 20.8 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR22242.1 - 0.00078 19.4 9.0 0.0042 17.0 6.2 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR22242.1 - 0.0034 17.0 10.6 0.0034 17.0 7.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAR22242.1 - 0.0054 16.5 1.4 0.012 15.4 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_A_type_inc PF04508.7 CAR22242.1 - 0.14 12.0 6.6 0.045 13.5 2.1 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat zf-RING_UBOX PF13445.1 CAR22242.1 - 0.23 11.1 8.3 1.2 8.8 5.8 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 CAR22242.1 - 1.2 8.7 6.4 21 4.7 4.5 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain OPA3 PF07047.7 CAR22243.1 - 2.2e-33 114.8 0.3 2.6e-33 114.6 0.2 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HAUS5 PF14817.1 CAR22243.1 - 0.022 13.3 2.2 0.033 12.7 1.5 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 HR1 PF02185.11 CAR22243.1 - 0.038 13.7 1.4 0.083 12.6 0.9 1.5 1 0 0 1 1 1 0 Hr1 repeat Atg14 PF10186.4 CAR22243.1 - 0.075 11.9 0.5 0.093 11.6 0.3 1.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 CAR22243.1 - 0.12 11.9 0.3 0.2 11.1 0.1 1.5 2 0 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 CAR22243.1 - 0.33 10.8 4.6 0.68 9.7 3.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Lebercilin PF15619.1 CAR22243.1 - 0.4 10.0 6.0 0.087 12.2 1.5 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Histone PF00125.19 CAR22244.1 - 6.4e-22 77.4 0.1 8.2e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR22244.1 - 0.0014 18.6 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PLA2_B PF01735.13 CAR22245.1 - 4.2e-221 734.3 4.8 5.2e-221 734.0 3.3 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TAF4 PF05236.9 CAR22246.1 - 5.9e-66 222.4 5.1 5.9e-66 222.4 3.5 2.3 3 0 0 3 3 3 1 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.8 CAR22246.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit RTC PF01137.16 CAR22247.1 - 7.6e-60 201.5 0.0 9e-60 201.2 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CAR22247.1 - 1.5e-32 111.6 0.0 2.4e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.19 CAR22248.1 - 1.2e-19 70.1 0.7 2.8e-19 68.9 0.1 1.9 2 0 0 2 2 2 1 PX domain DUF2404 PF10296.4 CAR22249.1 - 1.1e-06 28.7 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) Polyketide_cyc PF03364.15 CAR22250.1 - 5.2e-19 68.5 0.0 6.4e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 CAR22250.1 - 0.0024 18.0 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CG-1 PF03859.11 CAR22250.1 - 0.016 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 CG-1 domain SAP PF02037.22 CAR22251.1 - 2.4e-09 36.4 0.1 5.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 SAP domain DUF2076 PF09849.4 CAR22252.1 - 7e-07 29.5 9.9 8.4e-07 29.2 6.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CAR22252.1 - 0.00015 21.6 4.4 0.00022 21.0 3.0 1.3 1 0 0 1 1 1 1 CHCH domain NPBW PF15180.1 CAR22252.1 - 0.042 13.4 1.1 0.069 12.7 0.1 1.7 1 1 1 2 2 2 0 Neuropeptides B and W Med3 PF11593.3 CAR22252.1 - 0.057 12.6 8.3 0.067 12.4 5.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF605 PF04652.11 CAR22252.1 - 0.088 12.1 5.9 0.11 11.9 4.1 1.1 1 0 0 1 1 1 0 Vta1 like RAB3GAP2_N PF14655.1 CAR22252.1 - 0.12 11.3 0.2 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_FG PF13634.1 CAR22252.1 - 2.2 8.5 15.3 3.3 7.9 10.6 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region CcmD PF04995.9 CAR22253.1 - 0.091 12.5 0.7 0.2 11.3 0.5 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pex14_N PF04695.8 CAR22253.1 - 1.1 9.2 10.9 0.099 12.6 2.1 2.7 2 2 2 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Topoisom_I_N PF02919.10 CAR22254.1 - 3.1e-101 337.1 0.7 3.1e-101 337.1 0.5 2.8 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CAR22254.1 - 8.2e-84 280.3 0.6 8.2e-84 280.3 0.4 3.3 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CAR22254.1 - 6.4e-33 112.2 0.3 2.3e-32 110.4 0.2 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain MethyltransfD12 PF02086.10 CAR22254.1 - 0.0046 16.4 9.5 0.013 14.9 4.6 2.6 1 1 1 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Pkinase PF00069.20 CAR22255.1 - 3.5e-71 239.4 0.0 6.6e-71 238.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22255.1 - 3.7e-38 131.0 0.0 5.4e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CAR22255.1 - 2.2e-33 114.0 0.1 9.2e-17 60.7 0.1 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CAR22255.1 - 9e-09 34.7 0.0 2e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR22255.1 - 0.0071 15.4 0.0 0.019 14.0 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_3 PF08239.6 CAR22255.1 - 0.0095 16.1 0.1 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain RNA_pol_L_2 PF13656.1 CAR22256.1 - 1.8e-24 84.9 0.0 2.3e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CAR22256.1 - 3.9e-11 41.9 0.0 5.2e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PAH PF02671.16 CAR22257.1 - 4.9e-47 157.3 6.0 7.2e-19 67.1 0.5 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CAR22257.1 - 1.1e-42 143.8 0.2 3.3e-42 142.3 0.1 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor zf-DHHC PF01529.15 CAR22258.1 - 5.4e-33 113.8 13.9 5.4e-33 113.8 9.6 2.1 2 1 1 3 3 3 1 DHHC palmitoyltransferase ERO1 PF04137.10 CAR22258.1 - 0.026 13.5 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Transglut_core3 PF13471.1 CAR22258.1 - 0.1 12.3 0.5 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily HlyIII PF03006.15 CAR22259.1 - 5.1e-51 173.2 19.7 6.1e-51 172.9 13.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Arteri_GP4 PF02497.10 CAR22259.1 - 0.0031 17.4 0.7 0.0054 16.6 0.5 1.3 1 0 0 1 1 1 1 Arterivirus glycoprotein DNA_pol_A_exo1 PF01612.15 CAR22260.1 - 1.5e-44 151.5 0.7 2.3e-44 150.9 0.5 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CAR22260.1 - 5.3e-21 74.7 1.3 6.3e-20 71.2 0.0 2.8 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 CAR22260.1 - 1e-10 41.1 0.1 2.9e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Cyclin PF08613.6 CAR22261.1 - 5.5e-32 111.2 0.4 1.1e-31 110.2 0.3 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAR22261.1 - 0.032 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ras PF00071.17 CAR22262.1 - 1.5e-56 190.2 0.2 1.8e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR22262.1 - 6.2e-20 71.8 0.0 1.1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR22262.1 - 6.9e-15 54.7 0.0 7.8e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR22262.1 - 3.9e-07 29.4 0.1 4.5e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR22262.1 - 2.4e-06 27.1 0.2 8.1e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR22262.1 - 1.7e-05 24.7 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CAR22262.1 - 0.00019 20.6 0.1 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CAR22262.1 - 0.00028 21.0 0.0 0.00065 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR22262.1 - 0.0007 19.6 0.0 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 CAR22262.1 - 0.0017 17.9 0.3 0.062 12.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 CAR22262.1 - 0.0017 18.0 0.0 0.0084 15.8 0.0 1.9 2 0 0 2 2 2 1 NTPase MobB PF03205.9 CAR22262.1 - 0.0042 16.7 0.1 0.013 15.2 0.1 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CAR22262.1 - 0.0043 16.6 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CAR22262.1 - 0.0089 15.2 0.1 0.019 14.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 CAR22262.1 - 0.016 14.6 0.0 0.037 13.4 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CAR22262.1 - 0.023 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 CAR22262.1 - 0.024 14.3 0.1 0.061 13.0 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 CAR22262.1 - 0.034 13.6 0.1 0.081 12.4 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CAR22262.1 - 0.05 13.0 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 CAR22262.1 - 0.061 12.3 0.2 0.36 9.7 0.0 2.0 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 CAR22262.1 - 0.075 11.8 0.1 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pirin PF02678.11 CAR22263.1 - 2.4e-30 104.5 0.2 4.1e-29 100.5 0.0 2.2 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 CAR22263.1 - 3.1e-20 72.1 0.0 1.2e-19 70.3 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CAR22263.1 - 1.2e-05 24.7 1.2 0.00095 18.6 0.5 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 CAR22263.1 - 0.11 11.8 0.1 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Alg6_Alg8 PF03155.10 CAR22264.1 - 1.5e-153 512.0 27.9 1.8e-153 511.8 19.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPR_11 PF13414.1 CAR22265.1 - 9.4e-25 86.0 10.3 2.1e-16 59.3 2.4 3.3 3 1 1 4 4 3 2 TPR repeat TPR_1 PF00515.23 CAR22265.1 - 1.5e-19 68.7 4.4 4.4e-07 29.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR22265.1 - 2.9e-17 61.1 6.3 8.9e-06 25.2 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAR22265.1 - 1.7e-08 34.8 6.2 9.6e-08 32.5 2.1 2.6 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR22265.1 - 3.6e-08 33.2 6.0 0.0033 17.3 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR22265.1 - 1.1e-07 31.7 0.7 0.013 16.1 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CAR22265.1 - 7.6e-07 28.8 5.3 0.0096 16.0 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAR22265.1 - 8.6e-06 25.1 9.3 0.04 13.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 CAR22265.1 - 1.9e-05 25.0 0.6 0.00059 20.1 0.1 2.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_19 PF14559.1 CAR22265.1 - 5.4e-05 23.4 5.4 0.0012 19.1 0.2 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR22265.1 - 6.5e-05 22.4 1.4 0.37 10.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR22265.1 - 0.00011 21.9 0.5 0.18 11.7 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAR22265.1 - 0.00079 19.7 4.7 0.038 14.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAR22265.1 - 0.001 18.9 2.9 0.22 11.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat HMD PF03201.11 CAR22265.1 - 0.0047 16.8 2.8 0.013 15.4 1.9 1.8 1 0 0 1 1 1 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase TPR_15 PF13429.1 CAR22265.1 - 0.0065 15.5 1.6 0.012 14.7 1.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR22265.1 - 0.02 15.0 2.4 0.037 14.1 1.0 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CAR22265.1 - 0.043 13.7 2.1 23 4.9 0.0 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 CAR22265.1 - 0.055 13.9 0.1 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF627 PF04781.7 CAR22265.1 - 0.33 10.5 4.7 1.6 8.4 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF627) DUF3856 PF12968.2 CAR22265.1 - 1 9.1 4.7 15 5.4 1.4 3.1 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) VPS9 PF02204.13 CAR22266.1 - 2.2e-13 50.1 0.5 1.1e-12 47.8 0.1 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 CAR22266.1 - 0.0024 18.0 0.1 0.052 13.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAR22266.1 - 0.0073 16.7 0.2 0.79 10.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF367 PF04034.8 CAR22267.1 - 1.8e-53 179.4 0.0 2.5e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CAR22267.1 - 1.4e-15 56.6 0.3 2.4e-15 55.8 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DNA_ligase_A_M PF01068.16 CAR22268.1 - 5.2e-46 156.5 0.2 1.2e-45 155.4 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CAR22268.1 - 2.8e-19 69.5 0.0 4.9e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CAR22268.1 - 4.2e-08 33.4 0.0 2.2e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 CAR22268.1 - 6.2e-08 32.6 0.0 3.2e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 CAR22268.1 - 0.0022 17.6 0.2 0.12 12.0 0.0 2.7 1 1 1 2 2 2 1 mRNA capping enzyme, catalytic domain NPR2 PF06218.6 CAR22269.1 - 3.4e-164 546.6 1.0 5.8e-164 545.8 0.1 1.6 2 0 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.8 CAR22269.1 - 0.0019 16.8 1.5 0.0025 16.4 0.1 1.8 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Kinesin PF00225.18 CAR22270.1 - 1.4e-96 323.0 4.9 1.4e-96 323.0 3.4 2.8 2 1 0 2 2 2 1 Kinesin motor domain Bcl-2_3 PF15286.1 CAR22270.1 - 0.014 15.7 1.6 0.026 14.9 0.2 2.2 3 0 0 3 3 3 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like IncA PF04156.9 CAR22270.1 - 0.46 10.0 14.6 0.21 11.1 5.3 3.1 3 0 0 3 3 3 0 IncA protein Laminin_II PF06009.7 CAR22270.1 - 0.97 9.1 19.7 6.3 6.5 0.2 4.3 2 2 2 5 5 5 0 Laminin Domain II DUF1664 PF07889.7 CAR22270.1 - 1.6 8.5 18.7 0.78 9.5 1.8 4.9 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) Fcf1 PF04900.7 CAR22271.1 - 6e-32 109.7 0.4 1.1e-31 108.8 0.3 1.5 1 0 0 1 1 1 1 Fcf1 YL1 PF05764.8 CAR22271.1 - 0.16 11.5 4.4 0.25 10.9 3.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_S8 PF00082.17 CAR22273.1 - 8.3e-56 189.2 9.1 1.2e-55 188.6 6.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CAR22273.1 - 3.3e-11 43.6 0.2 1e-10 41.9 0.1 2.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 UPF0184 PF03670.8 CAR22273.1 - 0.091 12.9 0.1 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) AATase PF07247.7 CAR22274.1 - 1.8e-138 462.0 0.0 2.1e-138 461.8 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Lyase_1 PF00206.15 CAR22275.1 - 7e-116 386.7 0.0 9.2e-116 386.3 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CAR22275.1 - 1.5e-24 85.8 0.0 3.5e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Mating_N PF12731.2 CAR22275.1 - 0.046 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 Mitochondr_Som1 PF11093.3 CAR22276.1 - 7.1e-20 70.5 0.0 9.5e-20 70.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 PGM_PMM_I PF02878.11 CAR22277.1 - 1.3e-15 57.0 0.0 3.9e-09 36.1 0.0 2.6 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CAR22277.1 - 9.6e-11 41.9 0.0 6.7e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CAR22277.1 - 1.8e-10 40.6 0.2 4.2e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 CAR22277.1 - 0.0026 17.7 0.1 0.0067 16.4 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Kelch_3 PF13415.1 CAR22278.1 - 8.9e-33 111.7 7.7 1.5e-09 37.7 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CAR22278.1 - 9.1e-29 98.9 8.9 9.9e-07 28.4 0.2 7.1 6 1 1 7 7 7 6 Galactose oxidase, central domain DUF4110 PF13422.1 CAR22278.1 - 2.2e-27 94.6 0.8 2.2e-27 94.6 0.5 5.0 3 1 2 5 5 5 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 CAR22278.1 - 1.1e-21 75.9 13.9 2.4e-06 27.4 0.1 6.8 6 1 1 7 7 7 6 Kelch motif Kelch_5 PF13854.1 CAR22278.1 - 8.9e-11 41.5 9.1 0.031 14.2 0.0 5.6 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CAR22278.1 - 1.3e-10 40.6 6.0 0.002 17.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CAR22278.1 - 2.1e-08 33.6 12.3 0.43 10.4 0.0 6.4 6 0 0 6 6 6 4 Kelch motif WD40 PF00400.27 CAR22279.1 - 2.5e-25 87.3 3.4 5.1e-07 29.3 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CAR22279.1 - 4.4e-25 87.3 0.4 9.6e-25 86.2 0.3 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex AATase PF07247.7 CAR22280.1 - 1.2e-09 37.2 0.3 1.2e-09 37.2 0.2 2.2 2 1 0 2 2 2 1 Alcohol acetyltransferase DNA_pol_phi PF04931.8 CAR22281.1 - 4.1e-92 309.3 36.6 4.1e-91 306.0 25.4 2.1 1 1 0 1 1 1 1 DNA polymerase phi ABC_membrane PF00664.18 CAR22282.1 - 1.9e-53 181.6 6.6 2.5e-53 181.2 4.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CAR22282.1 - 5.6e-33 114.1 0.7 1.7e-32 112.6 0.0 2.2 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 CAR22282.1 - 1.6e-05 24.2 0.0 0.0049 16.1 0.0 3.1 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CAR22282.1 - 8.1e-05 22.1 0.1 0.41 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 CAR22282.1 - 0.0011 18.9 0.0 0.0039 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CAR22282.1 - 0.0015 18.6 0.1 0.3 10.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR22282.1 - 0.0015 19.3 0.0 0.0036 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CAR22282.1 - 0.0023 18.1 0.0 0.028 14.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CAR22282.1 - 0.0027 17.1 0.1 0.2 11.0 0.0 3.0 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.1 CAR22282.1 - 0.0061 16.6 0.1 0.071 13.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CAR22282.1 - 0.011 15.2 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.4 CAR22282.1 - 0.013 14.0 0.0 0.028 13.0 0.0 1.5 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 CAR22282.1 - 0.02 14.6 0.1 0.18 11.5 0.0 2.4 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 CAR22282.1 - 0.039 13.1 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 CAR22282.1 - 0.054 12.9 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 CAR22282.1 - 0.1 12.3 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 CAR22282.1 - 0.15 11.4 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CAR22282.1 - 0.16 11.9 0.7 0.94 9.4 0.1 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KAR9 PF08580.5 CAR22283.1 - 3.1e-42 144.7 14.8 6.8e-40 137.0 10.3 2.1 1 1 0 1 1 1 1 Yeast cortical protein KAR9 PilJ PF13675.1 CAR22283.1 - 0.017 15.4 2.4 0.21 11.8 0.0 2.9 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term PI-PLC-X PF00388.14 CAR22284.1 - 1e-45 154.7 0.0 2.5e-45 153.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CAR22284.1 - 6.6e-39 132.5 0.1 2.1e-38 130.9 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CAR22284.1 - 2.7e-05 24.0 2.3 0.00024 21.0 0.2 2.9 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 CAR22284.1 - 9.5e-05 22.4 1.2 0.017 15.2 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CAR22284.1 - 0.00013 20.9 0.0 0.00042 19.4 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_10 PF14788.1 CAR22284.1 - 0.00014 21.4 0.5 0.00039 20.0 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CAR22284.1 - 0.0042 16.8 0.1 0.021 14.6 0.1 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CAR22284.1 - 0.018 14.3 0.1 0.054 12.8 0.1 1.9 1 0 0 1 1 1 0 EF hand C2 PF00168.25 CAR22284.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 C2 domain GDPD PF03009.12 CAR22284.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_8 PF13833.1 CAR22284.1 - 0.068 12.7 0.6 0.3 10.7 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair RrnaAD PF00398.15 CAR22286.1 - 9.4e-62 208.3 0.0 1.2e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CAR22286.1 - 3.5e-10 39.9 0.0 5.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR22286.1 - 1.7e-05 25.3 0.0 3.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CAR22286.1 - 0.00071 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 CAR22286.1 - 0.0052 16.3 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 CAR22286.1 - 0.006 15.6 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 CAR22286.1 - 0.007 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CAR22286.1 - 0.0082 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR22286.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CAR22286.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CAR22286.1 - 0.092 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FMN_dh PF01070.13 CAR22287.1 - 2.3e-117 391.8 0.0 3.1e-117 391.4 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CAR22287.1 - 5.5e-21 74.1 0.0 3.8e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CAR22287.1 - 4.2e-08 32.5 0.3 1.8e-07 30.4 0.1 2.0 2 1 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 CAR22287.1 - 5.5e-06 25.7 0.0 8.3e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CAR22287.1 - 6e-05 22.0 1.2 0.015 14.1 0.1 3.0 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 CAR22287.1 - 0.031 13.5 0.0 6.3 5.9 0.0 2.5 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF561 PF04481.7 CAR22287.1 - 0.1 11.4 0.1 0.26 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF561) ThiG PF05690.9 CAR22287.1 - 0.11 11.4 0.1 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Dus PF01207.12 CAR22287.1 - 0.13 11.0 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Aminotran_3 PF00202.16 CAR22288.1 - 4.4e-57 193.4 0.0 5.2e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CAR22288.1 - 0.024 13.5 0.0 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II FMN_dh PF01070.13 CAR22289.1 - 1.3e-93 313.7 0.0 4.3e-93 311.9 0.0 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CAR22289.1 - 2.7e-22 78.3 0.0 5.8e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CAR22289.1 - 1.4e-09 37.3 0.0 2.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CAR22289.1 - 0.00057 18.8 0.2 0.0027 16.6 0.1 2.1 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 CAR22289.1 - 0.018 14.1 0.1 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase CK2S PF15011.1 CAR22289.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 Casein Kinase 2 substrate Ribonuc_L-PSP PF01042.16 CAR22290.1 - 1.8e-20 72.9 0.0 2.1e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HR1 PF02185.11 CAR22290.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Hr1 repeat ApbA_C PF08546.6 CAR22291.1 - 1.2e-29 102.8 0.0 3.9e-29 101.1 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CAR22291.1 - 9e-28 96.6 0.0 1.3e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 CAR22291.1 - 0.028 14.2 0.1 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 ThiF family Flocculin PF00624.13 CAR22292.1 - 3.1e-64 212.5 164.7 4.8e-14 51.9 8.2 10.6 8 2 3 11 11 11 7 Flocculin repeat Amidohydro_1 PF01979.15 CAR22294.1 - 6.8e-29 101.5 0.3 8.7e-29 101.2 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CAR22294.1 - 2.8e-15 57.1 0.0 4.8e-14 53.0 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 CAR22294.1 - 7.4e-13 48.1 0.0 2.9e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CAR22294.1 - 1.4e-10 40.9 2.9 1.1e-08 34.7 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family MFS_1 PF07690.11 CAR22295.1 - 3e-09 36.0 55.8 3.1e-07 29.4 37.4 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR22295.1 - 9.8e-06 24.3 11.2 9.8e-06 24.3 7.8 3.3 4 1 1 5 5 5 1 Sugar (and other) transporter Helicase_C PF00271.26 CAR22296.1 - 3.7e-12 45.9 0.0 9.5e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR22296.1 - 2.3e-09 36.9 0.0 9.7e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sir1 PF11603.3 CAR22296.1 - 0.0077 16.3 0.4 0.039 14.0 0.0 2.4 2 0 0 2 2 2 1 Regulatory protein Sir1 His_Phos_2 PF00328.17 CAR22297.1 - 5.2e-48 164.1 0.0 6.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1349 PF07081.6 CAR22298.1 - 8.2e-69 230.6 0.1 9.3e-69 230.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) PFU PF09070.6 CAR22298.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) DUP PF00674.13 CAR22299.1 - 7.8e-19 67.6 0.6 7.8e-19 67.6 0.4 2.1 1 1 1 2 2 2 1 DUP family HlyIII PF03006.15 CAR22299.1 - 0.015 14.7 1.2 0.025 14.0 0.9 1.3 1 0 0 1 1 1 0 Haemolysin-III related DUF1516 PF07457.6 CAR22299.1 - 0.11 12.5 1.8 0.18 11.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) LURAP PF14854.1 CAR22299.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein Transp_cyt_pur PF02133.10 CAR22300.1 - 7.5e-77 258.7 40.7 8.8e-77 258.5 28.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HRXXH PF13933.1 CAR22301.1 - 1.1e-74 251.0 0.0 1.3e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family DUP PF00674.13 CAR22302.1 - 3.1e-25 88.2 0.2 7.6e-15 54.7 0.1 2.6 2 0 0 2 2 2 2 DUP family CcdA PF07362.7 CAR22302.1 - 0.054 13.3 0.5 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA MFS_1 PF07690.11 CAR22303.1 - 8.8e-31 106.8 33.7 8.8e-31 106.8 23.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR22303.1 - 0.0038 15.8 38.3 0.058 11.9 8.5 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter Transglut_core PF01841.14 CAR22303.1 - 0.16 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily TPP_enzyme_N PF02776.13 CAR22304.1 - 4.5e-37 127.1 0.0 5.1e-36 123.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAR22304.1 - 5.9e-22 77.8 0.2 2.3e-20 72.7 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR22304.1 - 3.8e-21 75.2 0.0 9.1e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Ldh_1_N PF00056.18 CAR22305.1 - 7.4e-45 152.2 1.2 1.1e-44 151.6 0.9 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAR22305.1 - 4.4e-33 114.4 0.1 9e-33 113.4 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.9 CAR22305.1 - 0.00081 18.8 4.8 0.0033 16.8 1.7 2.5 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 CAR22305.1 - 0.00095 19.0 0.3 0.003 17.3 0.1 1.9 2 0 0 2 2 2 1 ThiF family Glyco_hydro_4 PF02056.11 CAR22305.1 - 0.00097 18.4 0.5 0.0077 15.5 0.0 2.5 3 0 0 3 3 3 1 Family 4 glycosyl hydrolase DAO PF01266.19 CAR22305.1 - 0.0019 17.1 0.4 0.0033 16.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CAR22305.1 - 0.0045 16.5 0.1 0.012 15.2 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 CAR22305.1 - 0.0061 16.7 0.1 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 CAR22305.1 - 0.0067 16.4 0.2 0.051 13.5 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 CAR22305.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CAR22305.1 - 0.028 14.0 0.6 0.058 13.0 0.4 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CAR22305.1 - 0.037 13.4 0.4 0.22 10.9 0.0 2.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 CAR22305.1 - 0.054 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CAR22305.1 - 0.067 12.5 0.7 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Glyco_trans_4_2 PF13477.1 CAR22305.1 - 0.074 12.8 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like Shikimate_DH PF01488.15 CAR22305.1 - 0.11 12.6 0.3 0.26 11.4 0.2 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 CAR22306.1 - 7.2e-131 436.8 24.6 8.1e-131 436.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR22306.1 - 1.6e-20 73.1 35.9 3.4e-17 62.2 8.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 CAR22307.1 - 2.3e-11 43.0 37.1 7.1e-11 41.4 25.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR22307.1 - 0.00054 18.6 10.2 0.00054 18.6 7.1 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CAR22307.1 - 0.0083 14.3 28.3 0.019 13.1 19.6 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SDA1 PF05285.7 CAR22308.1 - 0.012 14.9 7.5 0.014 14.7 5.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CAR22308.1 - 0.02 12.8 9.1 0.023 12.6 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family Rad4 PF03835.10 CAR22308.1 - 0.059 12.7 1.3 0.065 12.6 0.0 1.6 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain DUF434 PF04256.7 CAR22308.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF434) CDC45 PF02724.9 CAR22308.1 - 0.14 10.1 4.5 0.15 10.0 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 CAR22308.1 - 1.9 7.4 9.2 2.5 7.0 6.4 1.2 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.4 CAR22308.1 - 2.4 6.7 10.6 3.3 6.3 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ELFV_dehydrog PF00208.16 CAR22309.1 - 1.4e-82 276.9 4.8 1.7e-82 276.6 3.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CAR22309.1 - 2.4e-44 150.0 0.0 7e-44 148.5 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Sugar_tr PF00083.19 CAR22310.1 - 2.1e-97 326.5 23.9 2.5e-97 326.3 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR22310.1 - 6.6e-20 71.1 31.8 5.7e-19 68.0 14.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAR22310.1 - 0.00051 18.5 2.8 0.00051 18.5 1.9 3.9 3 1 1 4 4 4 1 MFS/sugar transport protein DUF1360 PF07098.6 CAR22310.1 - 0.023 14.4 0.0 0.083 12.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Fungal_trans_2 PF11951.3 CAR22311.1 - 2.1e-09 36.4 0.9 3.9e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR22311.1 - 3.8e-08 33.0 8.2 8.2e-08 32.0 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CAR22311.1 - 0.24 11.5 8.8 0.98 9.6 6.1 2.1 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ADH_N PF08240.7 CAR22312.1 - 3.5e-31 107.1 6.7 7.2e-31 106.1 4.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR22312.1 - 6.3e-21 74.2 0.0 9.9e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 CAR22312.1 - 0.0015 18.6 0.2 0.0024 17.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 CAR22312.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_binding_3 PF01494.14 CAR22312.1 - 0.027 13.5 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 CAR22312.1 - 0.047 13.7 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CAR22312.1 - 0.083 13.3 0.1 0.63 10.5 0.1 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Hexapep PF00132.19 CAR22312.1 - 0.091 12.3 0.7 0.24 10.9 0.5 1.8 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Pyr_redox_2 PF07992.9 CAR22312.1 - 0.097 12.5 0.3 0.17 11.7 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1380 PF07128.7 CAR22312.1 - 0.1 12.3 0.0 2.6 7.8 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1380) NAD_binding_8 PF13450.1 CAR22312.1 - 0.17 11.9 1.0 3.3 7.8 0.7 2.6 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Alb1 PF09135.6 CAR22313.1 - 2.3e-26 92.5 13.9 2.3e-26 92.5 9.7 1.8 2 0 0 2 2 2 1 Alb1 DUF1451 PF07295.6 CAR22313.1 - 0.034 13.9 1.8 0.038 13.7 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Cation_ATPase_C PF00689.16 CAR22314.1 - 0.026 14.0 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus FAM176 PF14851.1 CAR22314.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 CAR22314.1 - 0.041 13.2 0.1 0.05 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Conotoxin PF02950.12 CAR22314.1 - 0.13 13.0 0.4 0.36 11.6 0.3 1.8 1 1 0 1 1 1 0 Conotoxin Aldedh PF00171.17 CAR22315.1 - 1.9e-183 610.0 1.2 2.1e-183 609.8 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CAR22315.1 - 0.032 12.9 0.0 0.17 10.5 0.0 2.0 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) LRR_4 PF12799.2 CAR22316.1 - 1.3e-15 56.6 24.0 1.8e-05 24.2 1.8 7.6 4 3 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR22316.1 - 7.8e-13 47.9 25.5 2.8e-06 26.9 1.0 6.2 4 1 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 CAR22316.1 - 2.3e-08 32.9 25.7 0.16 12.1 0.2 10.0 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 CAR22316.1 - 2.8e-06 26.5 26.3 0.099 12.9 0.1 9.6 11 0 0 11 11 11 3 Leucine rich repeat LRR_6 PF13516.1 CAR22316.1 - 0.00027 20.6 21.6 0.18 11.9 0.1 8.5 8 2 1 9 9 9 1 Leucine Rich repeat LRR_9 PF14580.1 CAR22316.1 - 0.00078 19.0 5.6 0.66 9.5 0.2 3.5 3 0 0 3 3 3 3 Leucine-rich repeat LRR_3 PF07725.7 CAR22316.1 - 0.64 9.8 4.2 33 4.4 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Kelch_4 PF13418.1 CAR22318.1 - 5e-08 32.5 6.4 0.00014 21.5 0.5 6.2 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_3 PF13415.1 CAR22318.1 - 5.7e-07 29.5 8.6 0.0027 17.8 0.0 5.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CAR22318.1 - 4.4e-05 22.9 4.2 0.44 10.1 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 CAR22318.1 - 0.00099 19.1 5.0 0.1 12.8 0.1 5.1 6 0 0 6 6 6 1 Kelch motif Kelch_2 PF07646.10 CAR22318.1 - 0.24 11.2 6.2 1.2 9.0 0.3 4.6 6 0 0 6 6 6 0 Kelch motif GDI PF00996.13 CAR22319.1 - 1.6e-57 194.7 0.0 2e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Ribosomal_L7Ae PF01248.21 CAR22320.1 - 6.7e-23 80.0 0.2 9e-23 79.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 CAR22320.1 - 0.012 15.6 0.1 0.026 14.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Rad1 PF02144.11 CAR22321.1 - 4.8e-64 215.7 0.7 6e-64 215.4 0.5 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CH PF00307.26 CAR22322.1 - 4.6e-09 36.2 0.0 5.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain TRP PF06011.7 CAR22323.1 - 8.5e-159 528.8 31.8 8.5e-159 528.8 22.1 2.1 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CAR22323.1 - 2.5e-42 144.2 2.5 4.3e-42 143.5 1.7 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CAR22323.1 - 8.2e-05 22.8 0.1 0.00016 21.8 0.1 1.4 1 0 0 1 1 1 1 ML domain Miro PF08477.8 CAR22324.1 - 3.8e-41 140.3 0.0 1.7e-20 73.7 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 CAR22324.1 - 3.8e-28 97.0 0.0 1.3e-27 95.4 0.0 2.0 2 0 0 2 2 1 1 EF hand associated EF_assoc_1 PF08355.7 CAR22324.1 - 7.7e-28 95.5 0.9 1.4e-27 94.7 0.6 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 CAR22324.1 - 1.4e-24 86.3 0.0 1.3e-10 40.9 0.0 3.3 2 1 0 2 2 2 2 Ras family EF-hand_1 PF00036.27 CAR22324.1 - 1.7e-05 23.7 7.5 0.022 14.0 0.1 3.0 3 0 0 3 3 2 2 EF hand EF-hand_6 PF13405.1 CAR22324.1 - 2e-05 24.0 3.1 0.16 11.9 0.1 3.3 2 0 0 2 2 2 2 EF-hand domain Dynamin_N PF00350.18 CAR22324.1 - 5.5e-05 23.0 0.0 0.031 14.0 0.0 2.5 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 CAR22324.1 - 9.6e-05 22.3 0.0 0.041 13.8 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.1 CAR22324.1 - 0.00019 21.4 4.9 0.044 13.9 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair Arf PF00025.16 CAR22324.1 - 0.00046 19.4 0.0 0.53 9.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR22324.1 - 0.00057 19.3 0.0 1.9 7.9 0.0 3.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CAR22324.1 - 0.0017 18.3 0.0 0.91 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CAR22324.1 - 0.0069 15.9 0.0 0.068 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Septin PF00735.13 CAR22324.1 - 0.0074 15.3 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_10 PF12846.2 CAR22324.1 - 0.01 15.2 0.0 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 CAR22324.1 - 0.012 15.7 0.0 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CAR22324.1 - 0.047 12.8 0.0 0.32 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 CAR22324.1 - 0.049 13.2 0.1 2 8.0 0.0 3.1 3 1 1 4 4 4 0 NACHT domain MobB PF03205.9 CAR22324.1 - 0.058 13.1 0.0 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CAR22324.1 - 0.069 12.6 0.0 9 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_32 PF13654.1 CAR22324.1 - 0.13 10.9 0.0 1.2 7.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.1 CAR22324.1 - 0.66 9.4 9.1 2.9 7.3 0.9 3.0 3 0 0 3 3 3 0 EF hand Proteasome PF00227.21 CAR22325.1 - 1.2e-51 174.7 0.0 1.5e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR22325.1 - 8.2e-12 44.2 0.9 9.4e-12 44.0 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Mto2_bdg PF12808.2 CAR22326.1 - 0.0001 22.3 5.3 0.0001 22.3 3.7 4.9 4 1 0 4 4 4 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4094 PF13334.1 CAR22326.1 - 0.0073 16.6 1.5 0.0073 16.6 1.0 4.0 3 1 0 4 4 4 1 Domain of unknown function (DUF4094) DUF1014 PF06244.7 CAR22326.1 - 0.076 13.2 0.4 0.076 13.2 0.3 4.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1014) Nup54 PF13874.1 CAR22326.1 - 0.53 9.9 28.0 0.021 14.5 3.8 4.0 5 0 0 5 5 5 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.6 CAR22326.1 - 0.75 10.2 31.5 0.038 14.3 4.3 6.4 5 1 2 7 7 7 0 Syntaxin 6, N-terminal DUF479 PF04336.7 CAR22326.1 - 2.5 8.2 8.3 2.9 8.0 1.3 4.0 3 1 1 4 4 4 0 Protein of unknown function, DUF479 DUF4140 PF13600.1 CAR22326.1 - 8.7 6.8 29.3 2.6 8.5 0.1 7.1 7 0 0 7 7 7 0 N-terminal domain of unknown function (DUF4140) eIF2A PF08662.6 CAR22327.1 - 1e-28 100.3 1.6 4.7e-25 88.4 0.5 3.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CAR22327.1 - 1.3e-12 47.1 0.0 3.3e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR22327.1 - 7.2e-10 38.7 0.0 1.5e-08 34.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR22327.1 - 1.1e-07 31.5 0.0 4.3e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coatomer_WDAD PF04053.9 CAR22327.1 - 0.11 11.3 1.9 0.28 9.9 0.0 2.4 2 1 1 3 3 3 0 Coatomer WD associated region WD40 PF00400.27 CAR22327.1 - 0.11 12.3 0.7 1e+02 2.9 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat BolA PF01722.13 CAR22328.1 - 2.5e-18 65.7 0.0 3.4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein BolA PF01722.13 CAR22329.1 - 3.7e-25 87.6 0.4 5.1e-25 87.2 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein GCV_H PF01597.14 CAR22330.1 - 8.5e-45 151.3 0.2 1e-44 151.1 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein PDEase_I PF00233.14 CAR22331.1 - 6.3e-50 170.1 0.4 2.1e-49 168.3 0.2 1.8 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CAR22331.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 HD domain SAM_2 PF07647.12 CAR22332.1 - 1.5e-10 40.7 0.4 4.3e-10 39.2 0.0 2.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CAR22332.1 - 2.7e-06 27.4 0.0 6.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3453 PF11935.3 CAR22333.1 - 7.9e-60 202.2 0.0 1.7e-59 201.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) CBFD_NFYB_HMF PF00808.18 CAR22334.1 - 1.1e-22 79.8 1.7 1.4e-22 79.4 1.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CAR22334.1 - 3.8e-15 55.7 0.2 4.9e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 CAR22334.1 - 0.0016 18.2 0.2 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 CAR22334.1 - 0.11 12.4 0.2 0.18 11.7 0.1 1.4 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) PX PF00787.19 CAR22335.1 - 1.3e-20 73.2 0.1 1.9e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 PX domain COPIIcoated_ERV PF07970.7 CAR22336.1 - 1.5e-75 253.6 0.6 1.8e-75 253.3 0.4 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CAR22336.1 - 1.6e-31 108.1 0.1 3.7e-31 106.9 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1450 PF07293.6 CAR22336.1 - 2 8.4 7.0 5.9 6.9 4.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1450) RhoGEF PF00621.15 CAR22337.1 - 2.7e-39 134.8 1.3 2.7e-39 134.8 0.9 2.3 2 1 0 2 2 2 1 RhoGEF domain CDC24 PF06395.6 CAR22337.1 - 1.6e-37 127.4 0.9 4.1e-37 126.0 0.7 1.8 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.1 CAR22337.1 - 1.2e-19 70.6 1.6 2.2e-19 69.7 0.2 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PB1 PF00564.19 CAR22337.1 - 1.5e-05 24.5 0.8 6.1e-05 22.6 0.2 2.3 2 0 0 2 2 2 1 PB1 domain ETF_QO PF05187.8 CAR22338.1 - 8.4e-39 131.9 0.0 1.4e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CAR22338.1 - 3.5e-10 39.3 0.2 0.001 18.0 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR22338.1 - 5.3e-08 32.1 0.2 0.0032 16.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 CAR22338.1 - 1.5e-05 24.1 0.0 0.012 14.7 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 CAR22338.1 - 1.7e-05 24.7 0.1 7.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CAR22338.1 - 0.00013 20.6 0.2 0.012 14.0 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CAR22338.1 - 0.00036 20.4 0.0 0.00083 19.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR22338.1 - 0.0006 19.9 0.0 0.0029 17.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CAR22338.1 - 0.0014 17.7 0.2 0.016 14.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 CAR22338.1 - 0.0037 16.3 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CAR22338.1 - 0.0037 17.6 0.7 2.4 8.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR22338.1 - 0.0052 16.5 0.1 0.0096 15.7 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CAR22338.1 - 0.018 13.9 0.1 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 CAR22338.1 - 0.11 11.0 0.2 1.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase DUF164 PF02591.10 CAR22338.1 - 0.14 12.0 0.5 43 4.0 0.1 3.2 3 0 0 3 3 3 0 Putative zinc ribbon domain Phage_DNA_bind PF02303.12 CAR22339.1 - 0.12 12.4 0.1 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-destabilising protein DDHD PF02862.12 CAR22339.1 - 7.7 6.2 9.0 3.2 7.4 3.5 2.1 1 1 1 2 2 2 0 DDHD domain Cupin_8 PF13621.1 CAR22340.1 - 4e-52 177.2 0.0 5.1e-50 170.3 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CAR22340.1 - 0.0024 17.1 0.0 0.05 12.8 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein Cyclin_N PF00134.18 CAR22341.1 - 4e-28 97.5 0.2 7.5e-28 96.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DsbD PF02683.10 CAR22341.1 - 0.025 14.1 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region PPR_3 PF13812.1 CAR22342.1 - 0.00044 20.3 0.0 2.9 8.4 0.0 4.6 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 CAR22342.1 - 0.0029 17.4 0.3 3.3 7.9 0.0 4.1 4 0 0 4 4 4 1 PPR repeat Ribosomal_L17 PF01196.14 CAR22342.1 - 0.16 12.5 2.7 0.97 10.0 0.0 3.3 3 1 1 4 4 4 0 Ribosomal protein L17 Cyto_heme_lyase PF01265.12 CAR22343.1 - 1e-69 235.0 0.0 1.3e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase SOG2 PF10428.4 CAR22344.1 - 1.7e-122 409.3 11.9 2.6e-122 408.6 8.2 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein LRR_4 PF12799.2 CAR22344.1 - 5.5e-17 60.9 11.4 5.3e-09 35.4 0.2 4.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR22344.1 - 7.8e-14 51.1 10.9 1.1e-09 37.9 1.8 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CAR22344.1 - 2.2e-10 39.1 7.0 0.098 12.7 0.1 6.3 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CAR22344.1 - 1.2e-05 24.6 6.0 0.69 10.3 0.1 5.6 5 0 0 5 5 5 2 Leucine rich repeat SpecificRecomb PF10136.4 CAR22344.1 - 0.029 12.4 1.8 0.043 11.8 0.4 1.8 2 0 0 2 2 2 0 Site-specific recombinase LRR_6 PF13516.1 CAR22344.1 - 0.065 13.3 7.2 2.5 8.4 0.2 5.3 6 0 0 6 6 6 0 Leucine Rich repeat HeLo PF14479.1 CAR22345.1 - 0.04 13.6 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation Pkinase PF00069.20 CAR22346.1 - 2.6e-64 216.8 0.0 3.7e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22346.1 - 2.6e-29 102.1 0.0 3.8e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CAR22346.1 - 2.5e-14 53.1 0.2 3e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 CAR22346.1 - 1.3e-05 24.3 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR22346.1 - 0.0056 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MNE1 PF13762.1 CAR22347.1 - 3.7e-46 156.7 3.0 8.7e-46 155.5 2.1 1.6 1 0 0 1 1 1 1 Mitochondrial splicing apparatus component Aminotran_5 PF00266.14 CAR22349.1 - 3.6e-19 68.7 0.0 5.1e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CAR22349.1 - 3.3e-05 23.0 0.0 5.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II AA_permease PF00324.16 CAR22350.1 - 3.4e-132 441.1 39.1 3.9e-132 440.9 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR22350.1 - 1.1e-26 93.4 41.2 1.5e-26 92.9 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease PK PF00224.16 CAR22351.1 - 2.8e-168 558.9 1.1 3.5e-168 558.6 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CAR22351.1 - 1.7e-29 101.7 0.1 5.3e-29 100.1 0.1 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CAR22351.1 - 1.4e-05 24.1 0.5 2.9e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Peripla_BP_1 PF00532.16 CAR22351.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family IMS PF00817.15 CAR22352.1 - 1e-29 103.2 0.0 2.7e-29 101.8 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAR22352.1 - 3.5e-11 43.1 0.1 1.2e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 CAR22352.1 - 1.5e-09 37.8 0.1 3.9e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 CAR22352.1 - 0.001 18.9 0.0 0.004 17.1 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 CAR22352.1 - 0.003 17.3 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF4414 PF14377.1 CAR22352.1 - 0.0091 15.9 0.2 0.05 13.5 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4414) HLH PF00010.21 CAR22353.1 - 1.5e-21 75.7 0.1 1.5e-21 75.7 0.1 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Prenyltrans PF00432.16 CAR22353.1 - 0.046 13.2 4.1 9.5 5.8 0.0 4.1 4 0 0 4 4 4 0 Prenyltransferase and squalene oxidase repeat CbiG_N PF11760.3 CAR22354.1 - 0.013 15.1 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal S6PP PF05116.8 CAR22354.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase TGS PF02824.16 CAR22355.1 - 1.9e-21 75.6 0.1 3.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CAR22355.1 - 8e-17 61.2 0.1 2.1e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR22355.1 - 7.8e-09 35.0 0.0 2e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR22355.1 - 0.0013 18.5 0.4 1 9.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 CAR22355.1 - 0.0053 15.5 0.1 0.012 14.4 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 CAR22355.1 - 0.021 15.3 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 CAR22356.1 - 1.7e-32 112.3 2.5 1.8e-32 112.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CAR22356.1 - 2.8e-21 75.4 0.9 6.1e-21 74.3 0.0 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CAR22356.1 - 4.4e-14 52.3 4.1 2.6e-10 40.2 0.0 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR22356.1 - 1.1e-06 28.6 0.1 6.4e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR22356.1 - 0.0056 15.9 0.0 0.042 13.1 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_22 PF13401.1 CAR22356.1 - 0.014 15.4 0.1 0.074 13.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain DUF3107 PF11305.3 CAR22356.1 - 0.06 13.2 3.9 0.79 9.6 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) AAA_16 PF13191.1 CAR22356.1 - 0.64 9.9 0.0 0.64 9.9 0.0 3.9 3 1 0 3 3 3 0 AAA ATPase domain RNA_pol_Rpb1_5 PF04998.12 CAR22357.1 - 1.1e-98 329.9 1.2 1.1e-98 329.9 0.8 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CAR22357.1 - 4.5e-65 218.6 0.1 1.3e-64 217.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CAR22357.1 - 4.6e-41 140.1 0.2 7e-39 133.0 0.0 3.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CAR22357.1 - 2e-24 85.4 0.1 1.3e-23 82.8 0.0 2.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 CAR22357.1 - 1.6e-19 70.4 4.2 1.6e-19 70.4 2.9 3.6 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 DUF2890 PF11081.3 CAR22357.1 - 3.8 7.5 12.2 13 5.8 8.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Gly-zipper_Omp PF13488.1 CAR22358.1 - 0.00041 19.9 0.9 0.00053 19.5 0.6 1.3 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 CAR22358.1 - 0.023 14.3 2.6 0.023 14.3 1.8 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 CAR22358.1 - 0.5 10.0 12.1 0.69 9.6 1.6 1.8 1 1 1 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 CAR22358.1 - 4 7.0 10.6 5.5 6.5 7.3 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Fungal_trans PF04082.13 CAR22359.1 - 2.8e-08 32.9 0.0 4.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR22359.1 - 0.00023 21.0 9.6 0.00057 19.7 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SHS2_Rpb7-N PF03876.12 CAR22360.1 - 6.3e-13 48.6 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mis12 PF05859.7 CAR22361.1 - 1.6e-46 157.7 1.7 1.6e-46 157.7 1.2 1.7 2 0 0 2 2 2 1 Mis12 protein Kinesin-relat_1 PF12711.2 CAR22361.1 - 0.0021 18.4 1.7 0.007 16.7 1.2 1.9 1 0 0 1 1 1 1 Kinesin motor Vir_act_alpha_C PF10400.4 CAR22361.1 - 0.014 15.7 3.9 0.069 13.5 0.5 2.8 3 0 0 3 3 3 0 Virulence activator alpha C-term HrpB2 PF09487.5 CAR22361.1 - 0.096 12.8 0.4 0.25 11.5 0.2 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) UQ_con PF00179.21 CAR22362.1 - 7.7e-49 164.7 0.0 8.9e-49 164.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR22362.1 - 0.0027 17.4 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CAR22362.1 - 0.011 15.3 0.3 0.021 14.5 0.2 1.4 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CAR22362.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 RWD domain SWIRM PF04433.12 CAR22363.1 - 4e-13 49.3 0.0 7.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Fungal_trans PF04082.13 CAR22364.1 - 2.7e-32 111.6 0.1 4.7e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR22364.1 - 8.6e-08 31.9 10.8 1.4e-07 31.2 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2522 PF10747.4 CAR22364.1 - 0.1 12.6 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2522) UDP-g_GGTase PF06427.6 CAR22365.1 - 6.1e-06 25.7 0.0 1.8e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase DUF2507 PF10702.4 CAR22365.1 - 0.0071 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2507) tRNA-synt_2c PF01411.14 CAR22366.1 - 2.5e-224 745.6 0.4 5.4e-224 744.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CAR22366.1 - 3.6e-19 68.3 0.1 9.7e-19 66.9 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CAR22366.1 - 9.5e-07 28.4 0.4 2.4e-06 27.1 0.3 1.7 1 0 0 1 1 1 1 DHHA1 domain HVSL PF09749.4 CAR22366.1 - 0.056 12.4 0.2 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein RNase_P_Rpp14 PF01900.14 CAR22367.1 - 8.6e-32 109.2 0.3 1.1e-31 108.9 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family XRCC1_N PF01834.11 CAR22367.1 - 0.038 13.4 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 XRCC1 N terminal domain SKIP_SNW PF02731.10 CAR22368.1 - 5.5e-46 155.8 5.5 5.5e-46 155.8 3.8 2.2 2 0 0 2 2 2 2 SKIP/SNW domain CorA PF01544.13 CAR22370.1 - 1.1e-10 41.1 2.0 1.6e-10 40.5 1.4 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein vATP-synt_E PF01991.13 CAR22371.1 - 1.3e-55 187.7 19.9 1.5e-55 187.5 13.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.6 CAR22371.1 - 0.045 12.9 12.2 0.062 12.4 8.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M MMR_HSR1_C PF08438.5 CAR22371.1 - 0.076 13.2 0.2 0.076 13.2 0.1 2.3 2 1 0 2 2 2 0 GTPase of unknown function C-terminal Vps35 PF03635.12 CAR22371.1 - 0.11 10.6 8.3 0.12 10.4 5.8 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 PLRV_ORF5 PF01690.12 CAR22371.1 - 7.3 5.6 8.7 8.2 5.4 6.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNA_pol_A PF00476.15 CAR22372.1 - 1.4e-104 349.7 0.0 2.1e-104 349.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF2040 PF09745.4 CAR22373.1 - 3.7e-05 23.5 7.8 3.7e-05 23.5 5.4 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Synaptobrevin PF00957.16 CAR22375.1 - 1.2e-31 108.1 1.1 1.4e-31 107.9 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 CAR22375.1 - 0.063 11.8 0.2 0.076 11.5 0.1 1.0 1 0 0 1 1 1 0 TMEM117 protein family Myosin_head PF00063.16 CAR22376.1 - 2.4e-260 865.3 10.3 2.4e-260 865.3 7.2 2.0 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 CAR22376.1 - 4.7e-34 116.4 2.1 4.7e-34 116.4 1.5 2.4 2 0 0 2 2 1 1 DIL domain IQ PF00612.22 CAR22376.1 - 1.4e-06 27.4 20.8 0.42 10.4 0.0 6.5 7 0 0 7 7 6 3 IQ calmodulin-binding motif AAA_22 PF13401.1 CAR22376.1 - 6.6e-05 23.0 1.4 0.0012 19.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.1 CAR22376.1 - 0.00071 17.4 27.9 0.0011 16.7 19.4 1.2 1 0 0 1 1 1 1 AAA domain Myosin_N PF02736.14 CAR22376.1 - 0.0027 17.3 0.1 0.0073 15.9 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DivIC PF04977.10 CAR22376.1 - 0.034 13.6 33.0 0.17 11.3 3.0 5.4 3 2 1 4 4 4 0 Septum formation initiator Reo_sigmaC PF04582.7 CAR22376.1 - 0.045 12.9 16.5 0.086 12.0 8.7 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 CAR22376.1 - 0.089 13.0 0.0 0.089 13.0 0.0 3.3 2 1 0 2 2 1 0 ABC transporter AAA_19 PF13245.1 CAR22376.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain FlaC_arch PF05377.6 CAR22376.1 - 0.23 11.4 18.3 2.3 8.2 0.5 4.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 CAR22376.1 - 1.1 9.1 17.9 0.046 13.5 2.6 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Hph PF13694.1 CAR22377.1 - 9.4e-06 25.7 13.2 0.00097 19.2 0.7 3.1 1 1 1 2 2 2 2 Sec63/Sec62 complex-interacting family AAA_13 PF13166.1 CAR22377.1 - 7e-05 21.4 7.9 9.4e-05 21.0 5.5 1.1 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 CAR22377.1 - 0.016 14.4 6.4 0.022 13.9 3.8 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Filament PF00038.16 CAR22377.1 - 0.022 14.2 1.4 0.035 13.5 1.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein FliJ PF02050.11 CAR22377.1 - 0.041 13.9 0.7 0.085 12.9 0.5 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Med28 PF11594.3 CAR22377.1 - 0.089 13.0 0.8 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 28 THOC7 PF05615.8 CAR22377.1 - 0.16 12.2 4.0 1.3 9.3 0.4 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 DivIC PF04977.10 CAR22377.1 - 0.27 10.7 4.4 2.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator MscS_porin PF12795.2 CAR22377.1 - 0.59 9.4 8.5 1.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain IncA PF04156.9 CAR22377.1 - 1.2 8.6 14.0 5.1 6.6 0.1 2.7 2 1 0 3 3 3 0 IncA protein Lge1 PF11488.3 CAR22377.1 - 4.9 7.4 8.3 0.23 11.6 0.5 2.6 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 Saw1 PF11561.3 CAR22378.1 - 5.7e-40 137.0 0.1 1.3e-39 135.8 0.1 1.6 1 1 0 1 1 1 1 Single strand annealing-weakened 1 Aldedh PF00171.17 CAR22379.1 - 4.8e-12 44.9 0.0 1.2e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 CAR22379.1 - 0.036 12.9 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) E1-E2_ATPase PF00122.15 CAR22380.1 - 1.1e-18 67.1 1.9 2.1e-18 66.2 1.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CAR22380.1 - 4e-18 66.2 0.0 1.1e-17 64.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR22380.1 - 1.1e-14 55.3 0.2 2.4e-13 50.9 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR22380.1 - 7.6e-11 41.8 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR22380.1 - 0.0029 17.2 0.4 0.019 14.5 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR22380.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_L28e PF01778.12 CAR22381.1 - 8.8e-34 116.4 2.0 1.8e-33 115.4 1.4 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 CAR22381.1 - 2.2e-31 107.9 17.3 2.2e-31 107.9 12.0 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region CENP-T PF15511.1 CAR22381.1 - 0.025 13.8 10.9 0.029 13.6 7.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Latrophilin PF02354.11 CAR22381.1 - 0.33 9.6 3.9 0.52 8.9 2.7 1.3 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region RasGEF PF00617.14 CAR22382.1 - 9.2e-40 136.3 2.2 2.8e-39 134.7 1.5 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CAR22382.1 - 6.1e-16 58.4 2.3 2.3e-15 56.5 0.4 3.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Zn_clus PF00172.13 CAR22383.1 - 2.9e-11 43.0 9.7 4.9e-11 42.3 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LDB19 PF13002.2 CAR22384.1 - 2e-74 249.2 0.1 3e-74 248.6 0.1 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 CAR22384.1 - 0.00027 20.7 0.7 0.00054 19.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF2756 PF10956.3 CAR22384.1 - 0.13 12.5 2.0 3 8.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) PMT PF02366.13 CAR22385.1 - 3.3e-95 318.1 19.7 3.3e-95 318.1 13.7 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CAR22385.1 - 7.4e-27 94.1 0.0 1.2e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 MIR domain DUF4267 PF14087.1 CAR22385.1 - 0.051 13.1 1.6 0.15 11.6 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) Nucleoside_tran PF01733.13 CAR22386.1 - 3.6e-54 184.0 32.8 5.5e-38 130.8 6.7 3.0 2 1 1 3 3 3 2 Nucleoside transporter V_ATPase_I PF01496.14 CAR22386.1 - 0.025 12.4 3.2 0.035 11.9 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exo_endo_phos PF03372.18 CAR22387.1 - 3.2e-23 82.9 0.1 4.6e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CAR22387.1 - 1.1e-16 59.9 8.0 2.3e-09 36.6 1.3 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAR22387.1 - 4.4e-10 38.1 8.0 0.016 15.1 0.1 5.9 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_8 PF13855.1 CAR22387.1 - 1.5e-09 37.4 8.3 1.6e-09 37.3 1.0 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CAR22387.1 - 7.3e-09 34.3 4.2 0.0057 16.6 0.1 5.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CAR22387.1 - 0.026 14.5 7.1 0.53 10.5 0.0 4.7 4 1 1 5 5 5 0 Leucine Rich repeat RCC1_2 PF13540.1 CAR22388.1 - 5.6e-10 38.5 21.6 0.0046 16.5 0.1 5.6 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CAR22388.1 - 9.8e-09 35.3 9.0 0.0017 18.4 0.1 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.18 CAR22389.1 - 1.8e-70 237.0 0.5 1.8e-70 237.0 0.3 1.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR22389.1 - 2.5e-16 59.2 0.1 7.8e-15 54.5 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR22389.1 - 6.9e-10 38.6 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Med15_fungi PF05397.7 CAR22390.1 - 3.5e-38 130.1 6.5 3.5e-38 130.1 4.5 5.5 4 2 0 4 4 4 1 Mediator complex subunit 15 Taq-exonuc PF09281.5 CAR22390.1 - 1.1 9.3 7.1 0.6 10.2 1.8 2.8 2 0 0 2 2 2 0 Taq polymerase, exonuclease Spore_coat_CotO PF14153.1 CAR22390.1 - 4 6.8 71.8 0.6 9.5 16.9 3.9 3 0 0 3 3 3 0 Spore coat protein CotO Otopetrin PF03189.8 CAR22390.1 - 7.6 5.4 19.1 0.44 9.4 2.8 2.8 3 0 0 3 3 3 0 Otopetrin GSH_synth_ATP PF03917.12 CAR22391.1 - 1.3e-111 372.8 0.0 1.5e-111 372.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CAR22391.1 - 1.4e-34 118.3 0.0 2.2e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EI24 PF07264.6 CAR22393.1 - 1e-05 25.0 8.9 1.9e-05 24.2 6.1 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3487 PF11990.3 CAR22393.1 - 0.019 14.3 2.0 1.2 8.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) FecCD PF01032.13 CAR22394.1 - 0.013 14.3 1.6 0.013 14.3 1.1 2.1 2 0 0 2 2 2 0 FecCD transport family Pkinase PF00069.20 CAR22395.1 - 2.6e-61 207.0 0.0 4.4e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22395.1 - 5.3e-23 81.4 0.0 8.5e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR22395.1 - 5.5e-08 32.1 0.0 9.7e-08 31.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 CAR22395.1 - 7.1e-05 23.1 0.0 0.0022 18.3 0.0 2.6 2 0 0 2 2 2 1 PAS domain APH PF01636.18 CAR22395.1 - 0.0024 17.6 0.1 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR22395.1 - 0.0043 16.1 0.0 0.012 14.6 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAR22395.1 - 0.0063 15.8 1.2 0.011 15.0 0.1 1.9 2 0 0 2 2 2 1 RIO1 family PAS PF00989.19 CAR22395.1 - 0.014 15.1 0.0 2.7 7.8 0.0 2.8 2 1 0 2 2 2 0 PAS fold OstA_2 PF13100.1 CAR22396.1 - 0.036 13.4 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 OstA-like protein HEAT PF02985.17 CAR22397.1 - 4e-39 129.1 21.3 0.0023 17.8 0.0 12.8 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.1 CAR22397.1 - 5.4e-32 109.9 0.3 9.2e-07 29.0 0.0 8.5 3 3 5 8 8 8 6 HEAT repeats Vac14_Fab1_bd PF12755.2 CAR22397.1 - 3.1e-11 43.5 6.4 0.045 14.1 0.0 7.7 3 3 3 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CAR22397.1 - 4.3e-10 39.7 14.0 4.9 7.7 0.0 8.6 9 1 1 10 10 10 5 HEAT-like repeat Arm PF00514.18 CAR22397.1 - 0.026 14.3 1.5 11 6.0 0.0 4.7 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 CAR22397.1 - 1.1 9.0 8.2 17 5.1 0.0 4.9 3 3 3 6 6 6 0 non-SMC mitotic condensation complex subunit 1 HhH-GPD PF00730.20 CAR22398.1 - 5.5e-18 65.2 0.0 9.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CAR22398.1 - 9.7e-05 21.8 0.0 0.0003 20.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Exo_endo_phos PF03372.18 CAR22399.1 - 4.6e-18 66.0 0.0 5.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Activator_LAG-3 PF11498.3 CAR22400.1 - 0.086 11.5 41.3 0.01 14.6 23.7 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 AAA_23 PF13476.1 CAR22400.1 - 0.089 13.1 6.5 0.11 12.8 4.5 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 CAR22400.1 - 0.11 12.4 7.3 0.13 12.1 5.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FimP PF09766.4 CAR22400.1 - 0.17 10.9 17.7 0.3 10.1 12.3 1.3 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 CAR22400.1 - 0.32 9.1 32.3 0.39 8.9 22.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3298 PF11738.3 CAR22400.1 - 0.67 10.5 3.9 1.6 9.2 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) DUF1266 PF06889.6 CAR22400.1 - 1.2 8.9 7.9 1.7 8.4 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) FAM60A PF15396.1 CAR22400.1 - 1.8 8.2 9.3 1.7 8.3 4.1 2.0 2 0 0 2 2 2 0 Protein Family FAM60A DUF3371 PF11851.3 CAR22400.1 - 7.8 7.2 17.0 2.6 8.7 9.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF4557 PF15101.1 CAR22400.1 - 8.4 6.1 17.5 2.1 8.1 10.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) SNARE PF05739.14 CAR22401.1 - 2.2e-08 33.6 2.4 6.4e-08 32.1 1.0 2.3 3 0 0 3 3 3 1 SNARE domain RRM_1 PF00076.17 CAR22402.1 - 3.5e-20 71.4 3.5 8.4e-16 57.3 0.2 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR22402.1 - 1.5e-13 50.5 0.3 3.8e-10 39.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR22402.1 - 2.7e-13 49.5 1.1 3.7e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 CAR22403.1 - 1.4e-45 155.4 0.8 3e-45 154.2 0.0 2.0 2 0 0 2 2 2 1 Sds3-like Ribosomal_S19 PF00203.16 CAR22404.1 - 3.3e-32 109.9 0.1 4.6e-32 109.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 CAR22405.1 - 2.6e-25 88.6 13.7 3.1e-25 88.3 9.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cys_Met_Meta_PP PF01053.15 CAR22406.1 - 6.5e-144 478.9 0.0 7.4e-144 478.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CAR22406.1 - 0.0026 16.1 0.0 0.004 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CAR22406.1 - 0.048 12.3 0.0 0.087 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CAR22406.1 - 0.051 12.2 0.1 0.22 10.2 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CAR22406.1 - 0.097 11.6 1.0 3.9 6.3 0.1 2.6 2 1 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF775 PF05603.7 CAR22408.1 - 1.3e-57 194.5 0.0 1.5e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) tRNA-synt_1c PF00749.16 CAR22409.1 - 2e-107 358.4 0.0 4e-107 357.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain SMC_N PF02463.14 CAR22410.1 - 1.5e-24 86.4 14.1 6.5e-24 84.3 9.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR22410.1 - 1.5e-21 77.6 0.5 1.5e-21 77.6 0.3 4.8 2 2 2 4 4 3 1 AAA domain AAA_21 PF13304.1 CAR22410.1 - 1.4e-05 25.2 0.9 8.1e-05 22.7 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CAR22410.1 - 0.00013 21.4 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CAR22410.1 - 0.0067 15.8 0.1 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CAR22410.1 - 0.018 15.3 17.5 0.086 13.1 0.0 4.9 3 2 0 4 4 4 0 ABC transporter MutS_V PF00488.16 CAR22410.1 - 0.019 14.3 0.0 0.096 12.0 0.0 2.1 2 0 0 2 2 2 0 MutS domain V NTS_2 PF15448.1 CAR22410.1 - 0.027 14.7 0.1 0.13 12.6 0.0 2.2 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein AAA_10 PF12846.2 CAR22410.1 - 0.028 13.8 3.1 0.26 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Reo_sigmaC PF04582.7 CAR22410.1 - 1.4 7.9 13.6 0.75 8.9 2.7 3.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein AAA_17 PF13207.1 CAR22410.1 - 9.4 7.0 7.5 2 9.2 0.5 3.5 2 1 1 3 3 3 0 AAA domain DUF3722 PF12519.3 CAR22412.1 - 9.7e-84 280.6 10.0 1.5e-83 280.0 6.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) IGPD PF00475.13 CAR22412.1 - 0.053 13.3 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase Pollen_allerg_2 PF01620.11 CAR22412.1 - 0.092 13.0 0.0 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) Spo7 PF03907.8 CAR22413.1 - 8.9e-89 296.5 4.2 1.1e-88 296.3 2.9 1.1 1 0 0 1 1 1 1 Spo7-like protein Phage_holin_4 PF05105.7 CAR22413.1 - 0.036 13.7 0.4 0.057 13.1 0.3 1.2 1 0 0 1 1 1 0 Holin family DUF4538 PF15061.1 CAR22413.1 - 0.039 13.2 0.2 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Sdh_cyt PF01127.17 CAR22413.1 - 0.049 13.4 1.2 0.096 12.5 0.8 1.5 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit OPT PF03169.10 CAR22413.1 - 0.063 11.7 0.0 0.082 11.3 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Voltage_CLC PF00654.15 CAR22413.1 - 0.084 11.8 0.2 0.099 11.6 0.1 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel B56 PF01603.15 CAR22414.1 - 1.6e-146 488.0 14.3 6e-139 463.1 7.4 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) FUN14 PF04930.10 CAR22415.1 - 2.8e-06 27.5 4.0 3.7e-06 27.1 1.3 2.1 2 1 0 2 2 2 1 FUN14 family MtrF PF09472.5 CAR22415.1 - 1.2 8.4 6.1 0.85 8.9 0.1 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) zf-CCCH PF00642.19 CAR22416.1 - 2.8e-12 46.0 28.3 0.00033 20.2 0.4 5.6 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAR22416.1 - 0.0078 16.1 25.1 0.036 14.0 0.4 5.2 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 CAR22417.1 - 8.6e-29 100.4 0.0 1.2e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22417.1 - 4.9e-11 42.2 0.0 7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR22417.1 - 0.0035 17.1 0.2 0.059 13.0 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pil1 PF13805.1 CAR22418.1 - 1.1e-151 503.5 0.4 1.5e-151 503.0 0.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 COG4 PF08318.7 CAR22419.1 - 4.5e-98 328.0 4.2 7.6e-98 327.3 2.9 1.4 1 0 0 1 1 1 1 COG4 transport protein DUF2450 PF10475.4 CAR22419.1 - 0.0001 21.3 5.0 0.00024 20.1 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF3508 PF12018.3 CAR22419.1 - 1.7 7.5 11.7 0.14 11.0 1.8 3.1 2 2 0 3 3 3 0 Domain of unknown function (DUF3508) DUF148 PF02520.12 CAR22419.1 - 7.7 6.3 11.4 1.2 8.9 1.8 3.4 4 0 0 4 4 4 0 Domain of unknown function DUF148 Fork_head PF00250.13 CAR22420.1 - 6.3e-32 109.4 0.3 1.4e-31 108.3 0.2 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CAR22420.1 - 2.5e-11 43.5 0.2 4.6e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain Peptidase_S46 PF10459.4 CAR22420.1 - 0.092 11.1 10.6 0.15 10.4 7.4 1.2 1 0 0 1 1 1 0 Peptidase S46 Proteasome PF00227.21 CAR22421.1 - 6e-49 165.9 0.1 7.3e-49 165.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 CAR22422.1 - 4.3e-56 189.9 0.0 6.9e-54 182.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22422.1 - 2.2e-28 99.0 0.4 3.1e-25 88.7 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CAR22422.1 - 0.0021 16.9 0.7 0.0045 15.8 0.0 1.7 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CAR22422.1 - 0.044 12.8 0.1 0.079 12.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.24 CAR22423.1 - 1.3e-09 37.5 9.4 1.3e-09 37.5 6.5 2.4 2 0 0 2 2 2 1 PHD-finger SET PF00856.23 CAR22423.1 - 1.8e-05 25.1 2.2 0.0012 19.1 0.0 2.9 2 1 0 2 2 2 1 SET domain PHD_2 PF13831.1 CAR22423.1 - 0.046 13.0 13.7 0.014 14.7 3.3 2.4 2 0 0 2 2 2 0 PHD-finger zf-CW PF07496.10 CAR22423.1 - 0.059 13.0 1.6 0.14 11.9 1.1 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Pam16 PF03656.8 CAR22424.1 - 5.9e-45 152.1 2.4 7e-45 151.9 1.7 1.0 1 0 0 1 1 1 1 Pam16 Coatomer_WDAD PF04053.9 CAR22424.1 - 0.073 11.8 0.0 0.094 11.4 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region zf-CCCH PF00642.19 CAR22425.1 - 5.3e-06 25.9 39.1 0.00095 18.7 0.8 5.5 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2HC5 PF06221.8 CAR22426.1 - 4.5e-21 74.3 6.6 7.6e-21 73.6 4.6 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type VIT1 PF01988.14 CAR22426.1 - 0.48 9.8 0.1 0.48 9.8 0.0 2.3 2 1 0 2 2 2 0 VIT family DEAD PF00270.24 CAR22427.1 - 6.8e-38 129.8 0.0 1.2e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR22427.1 - 5.3e-19 67.8 0.0 1.1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CAR22427.1 - 2.2e-18 65.5 0.0 5.9e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) HTH_Mga PF08280.6 CAR22427.1 - 0.11 12.2 1.6 32 4.3 0.0 3.7 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Sin_N PF04801.8 CAR22428.1 - 9e-19 67.6 0.0 1.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Sin-like protein conserved region IF-2B PF01008.12 CAR22429.1 - 2.9e-76 256.1 0.0 3.3e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family GTP_EFTU PF00009.22 CAR22430.1 - 1.3e-55 187.8 0.0 2.1e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CAR22430.1 - 2.2e-27 94.6 0.0 8.2e-27 92.8 0.0 2.1 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CAR22430.1 - 8.9e-19 67.1 0.4 1.9e-17 62.8 0.3 2.6 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR22430.1 - 3.6e-08 33.3 2.6 1.1e-07 31.8 0.9 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GCS PF03074.11 CAR22431.1 - 1e-143 478.8 0.0 1.5e-143 478.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase PI3_PI4_kinase PF00454.22 CAR22432.1 - 4.8e-54 183.3 0.0 6.9e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ChAPs PF09295.5 CAR22433.1 - 1.3e-51 175.6 0.1 5.2e-40 137.4 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CAR22433.1 - 3.4e-06 26.6 0.1 6.8e-05 22.4 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 CAR22433.1 - 1.8e-05 24.9 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR22433.1 - 0.00012 21.6 0.0 0.029 14.2 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR22433.1 - 0.0027 17.2 0.3 0.023 14.2 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR22433.1 - 0.0034 17.2 0.1 0.017 15.0 0.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR22433.1 - 0.0074 16.8 0.1 1.3 9.8 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR22433.1 - 0.01 16.4 0.0 0.033 14.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR22433.1 - 0.04 13.6 0.3 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CAR22433.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CAR22433.1 - 0.062 13.1 0.2 0.32 10.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAR22433.1 - 0.074 13.2 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SAPS PF04499.10 CAR22434.1 - 4.2e-173 576.3 0.1 4.2e-173 576.3 0.0 2.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein PTPLA PF04387.9 CAR22435.1 - 8.5e-49 165.1 7.6 8.5e-49 165.1 5.2 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_L21p PF00829.16 CAR22436.1 - 1.2e-06 28.5 0.1 1.5e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.20 CAR22437.1 - 5.5e-67 225.6 0.0 1.2e-66 224.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22437.1 - 1.6e-43 148.7 0.0 2.6e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR22437.1 - 9.3e-11 41.2 0.0 1.8e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CAR22437.1 - 0.28 10.9 0.0 0.48 10.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ion_trans_2 PF07885.11 CAR22438.1 - 1.5e-27 95.1 32.6 1.5e-17 63.0 5.5 3.4 4 0 0 4 4 4 2 Ion channel Lig_chan PF00060.21 CAR22438.1 - 0.56 9.9 14.7 0.45 10.2 0.4 3.8 3 1 1 4 4 4 0 Ligand-gated ion channel UvrD_C PF13361.1 CAR22439.1 - 1.8e-67 228.3 0.0 2.7e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CAR22439.1 - 1.2e-60 205.4 0.0 2.8e-60 204.2 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CAR22439.1 - 1.8e-08 34.4 0.3 5e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CAR22439.1 - 4.8e-08 32.6 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CAR22439.1 - 0.055 13.0 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain GWT1 PF06423.7 CAR22440.1 - 6.7e-44 149.2 5.6 6.7e-44 149.2 3.9 2.5 2 0 0 2 2 2 1 GWT1 BatA PF07584.6 CAR22440.1 - 0.034 14.3 2.2 0.19 11.9 1.4 2.5 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal BRCT PF00533.21 CAR22441.1 - 2.1e-13 50.1 0.2 0.00014 21.9 0.0 4.5 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CAR22441.1 - 2.6e-12 46.4 0.1 1e-05 25.2 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain MAD PF05557.8 CAR22441.1 - 0.068 11.2 0.0 0.095 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Zn_clus PF00172.13 CAR22442.1 - 3.5e-10 39.6 9.7 7.5e-10 38.5 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTR2 PF15458.1 CAR22443.1 - 3.7e-36 124.6 16.7 3.7e-36 124.6 11.5 1.9 1 1 1 2 2 2 1 Nineteen complex-related protein 2 PRP3 PF08572.5 CAR22443.1 - 2.5 7.4 10.9 1.8e+02 1.3 7.5 2.4 1 1 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) PI3_PI4_kinase PF00454.22 CAR22444.1 - 2.6e-42 144.9 0.0 1.1e-41 142.8 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CAR22444.1 - 3.4e-25 88.2 0.1 3.4e-25 88.2 0.1 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Aconitase PF00330.15 CAR22445.1 - 2.5e-179 596.6 0.0 4.6e-179 595.7 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAR22445.1 - 2.8e-46 156.8 0.0 5.8e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Cys_Met_Meta_PP PF01053.15 CAR22446.1 - 5.6e-147 489.0 0.0 6.4e-147 488.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CAR22446.1 - 3.3e-12 46.1 0.1 6.3e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CAR22446.1 - 3.8e-10 39.2 0.0 5.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CAR22446.1 - 2e-08 33.3 0.1 3.6e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR22446.1 - 1.2e-07 31.1 0.0 2.6e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CAR22446.1 - 0.00011 20.6 0.8 0.00035 19.0 0.6 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CAR22446.1 - 0.0053 15.5 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein CPSase_L_D2 PF02786.12 CAR22446.1 - 0.073 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Radical_SAM PF04055.16 CAR22446.1 - 0.13 12.3 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily Zn_clus PF00172.13 CAR22447.1 - 3.2e-06 26.9 11.2 5.9e-06 26.0 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gtr1_RagA PF04670.7 CAR22448.1 - 4.6e-68 228.8 0.3 5.6e-68 228.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CAR22448.1 - 0.0087 15.3 0.0 0.018 14.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_14 PF13173.1 CAR22448.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3294 PF07957.6 CAR22448.1 - 0.083 12.4 0.0 13 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) DUF2118 PF09891.4 CAR22448.1 - 0.1 12.3 0.4 3 7.5 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) DUF815 PF05673.8 CAR22448.1 - 0.14 11.1 0.0 0.29 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TYW3 PF02676.9 CAR22449.1 - 1e-64 217.4 0.0 1.3e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF678 PF05077.7 CAR22449.1 - 0.11 12.5 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) MIF4G PF02854.14 CAR22450.1 - 4.4e-43 147.1 0.1 6e-43 146.6 0.1 1.2 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CAR22450.1 - 1.7e-26 91.9 0.1 9.4e-26 89.5 0.1 2.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 AAA PF00004.24 CAR22451.1 - 4.7e-43 146.5 0.0 8.8e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CAR22451.1 - 2.4e-06 27.5 0.0 4.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CAR22451.1 - 2.5e-06 27.2 0.0 1.8e-05 24.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAR22451.1 - 7.1e-06 26.1 0.1 0.00037 20.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR22451.1 - 2.8e-05 24.1 0.0 0.00013 21.9 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CAR22451.1 - 4e-05 24.4 0.2 0.00013 22.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR22451.1 - 0.00013 21.6 0.1 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CAR22451.1 - 0.00015 20.9 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CAR22451.1 - 0.00025 20.5 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CAR22451.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR22451.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAR22451.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR22451.1 - 0.0032 16.5 0.0 0.0066 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF2072 PF09845.4 CAR22451.1 - 0.0043 16.9 0.4 0.0091 15.9 0.3 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_3 PF07726.6 CAR22451.1 - 0.0056 16.2 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CAR22451.1 - 0.0063 16.8 0.7 0.032 14.5 0.0 2.5 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CAR22451.1 - 0.01 15.0 0.2 0.025 13.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CAR22451.1 - 0.01 14.5 0.0 0.023 13.4 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 CAR22451.1 - 0.013 14.7 0.0 0.046 12.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 CAR22451.1 - 0.025 14.0 0.0 0.16 11.4 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 CAR22451.1 - 0.027 13.8 0.1 0.087 12.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CAR22451.1 - 0.034 13.7 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAR22451.1 - 0.041 14.0 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CAR22451.1 - 0.071 12.7 0.0 0.35 10.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 CAR22451.1 - 0.084 11.7 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CAR22451.1 - 0.087 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_tran_28_C PF04101.11 CAR22452.1 - 1.7e-21 76.6 0.0 1.1e-20 73.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CAR22452.1 - 0.00028 20.2 0.0 0.00036 19.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 MerR_2 PF13591.1 CAR22453.1 - 0.013 15.0 0.8 0.023 14.2 0.5 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF2046 PF09755.4 CAR22453.1 - 0.028 13.3 0.1 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Cep57_CLD_2 PF14197.1 CAR22453.1 - 0.95 9.4 6.5 3.8 7.5 4.4 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 zf-CHY PF05495.7 CAR22454.1 - 1.2 9.3 5.1 6 7.1 1.8 2.4 2 0 0 2 2 2 0 CHY zinc finger RRM_1 PF00076.17 CAR22455.1 - 2.2e-41 139.3 0.0 1.6e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR22455.1 - 3.1e-29 100.7 0.0 2.7e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR22455.1 - 2.2e-21 75.4 0.0 2.9e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arrestin_N PF00339.24 CAR22456.1 - 2e-19 69.8 0.0 5.4e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CAR22456.1 - 2.6e-05 24.3 0.7 0.00022 21.3 0.1 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 CAR22456.1 - 0.0021 16.8 0.2 0.053 12.3 0.0 2.5 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 26 RNase_PH PF01138.16 CAR22457.1 - 3.4e-22 79.1 0.1 4.6e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.8 CAR22458.1 - 6.5e-55 183.7 6.5 2.6e-29 101.4 0.3 3.0 2 0 0 2 2 2 2 Phospholipid methyltransferase PITH PF06201.8 CAR22459.1 - 1.6e-39 135.1 0.3 1.9e-39 134.8 0.2 1.1 1 0 0 1 1 1 1 PITH domain ALAD PF00490.16 CAR22460.1 - 1.2e-112 375.9 0.0 1.4e-112 375.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Snf7 PF03357.16 CAR22461.1 - 7.5e-30 103.5 3.7 8.9e-30 103.3 2.5 1.1 1 0 0 1 1 1 1 Snf7 DUF1989 PF09347.5 CAR22462.1 - 1.1e-49 168.0 0.0 1.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) PALP PF00291.20 CAR22463.1 - 4.8e-58 196.7 0.0 6.2e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CAR22463.1 - 1.5e-13 50.2 0.0 4.7e-10 39.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain ComZ PF10815.3 CAR22464.1 - 7.6e-05 22.4 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 ComZ DUF1641 PF07849.6 CAR22464.1 - 0.037 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TFIIS_M PF07500.9 CAR22465.1 - 8.9e-28 96.6 0.4 8.9e-28 96.6 0.3 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CAR22465.1 - 4e-17 61.5 6.1 6.4e-17 60.8 4.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CAR22465.1 - 3.1e-14 52.2 0.6 3.1e-14 52.2 0.4 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain VHS PF00790.14 CAR22465.1 - 0.066 12.8 0.4 0.37 10.4 0.1 2.3 1 1 1 2 2 2 0 VHS domain DUF4615 PF15393.1 CAR22465.1 - 0.43 10.8 3.7 0.24 11.6 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) RRM_1 PF00076.17 CAR22466.1 - 4e-20 71.2 0.0 7.2e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR22466.1 - 2.2e-13 49.9 0.0 4.7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR22466.1 - 2.7e-10 39.9 0.0 4.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CAR22466.1 - 1.1e-07 30.9 1.0 3e-07 29.5 0.7 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.1 CAR22466.1 - 1.2e-07 31.6 1.0 1.2e-07 31.6 0.7 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 DUF4332 PF14229.1 CAR22466.1 - 0.0069 16.3 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) DUF2305 PF10230.4 CAR22466.1 - 0.058 12.8 0.1 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) CSTF2_hinge PF14327.1 CAR22467.1 - 2.3e-25 88.4 1.2 2.3e-25 88.4 0.9 2.4 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 CAR22467.1 - 0.00018 21.0 0.0 0.00091 18.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CAR22467.1 - 0.00027 20.1 4.1 0.00062 18.9 2.8 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 CAR22467.1 - 0.034 14.1 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Aminotran_1_2 PF00155.16 CAR22468.1 - 9.1e-80 268.3 0.0 1e-79 268.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SNARE PF05739.14 CAR22469.1 - 2.2e-18 65.6 2.7 2.2e-18 65.6 1.9 2.7 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 CAR22469.1 - 3.5e-18 65.6 4.4 1.9e-17 63.2 0.1 3.0 2 1 0 3 3 3 1 Syntaxin Sed5p PF11416.3 CAR22469.1 - 1.1e-09 37.5 2.7 3e-09 36.1 0.2 2.4 2 0 0 2 2 2 1 Integral membrane protein Sed5p Glutaredoxin2_C PF04399.8 CAR22469.1 - 0.0074 15.8 3.8 0.2 11.2 0.0 3.2 3 0 0 3 3 3 1 Glutaredoxin 2, C terminal domain MCPsignal PF00015.16 CAR22469.1 - 0.01 15.3 0.5 0.01 15.3 0.4 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MAGE_N PF12440.3 CAR22469.1 - 0.055 13.7 4.1 0.14 12.4 2.9 1.7 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Serine_rich PF08824.5 CAR22469.1 - 0.059 13.0 3.1 4.1 7.0 0.1 2.4 2 1 0 2 2 2 0 Serine rich protein interaction domain DUF1664 PF07889.7 CAR22469.1 - 0.41 10.4 5.5 0.26 11.1 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2422 PF10337.4 CAR22469.1 - 0.72 8.5 5.5 0.39 9.4 1.5 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2422) FlaC_arch PF05377.6 CAR22469.1 - 0.86 9.5 3.8 4.5 7.2 0.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.10 CAR22469.1 - 1.1 9.4 6.1 0.3 11.2 0.2 2.8 3 2 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus Atg14 PF10186.4 CAR22469.1 - 1.4 7.8 8.9 1.6 7.5 0.5 2.9 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CAR22469.1 - 2 8.0 13.5 0.079 12.5 1.7 2.9 2 1 1 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 CAR22469.1 - 2.5 8.5 7.8 5 7.5 0.1 3.3 3 1 1 4 4 4 0 Syntaxin 6, N-terminal FadA PF09403.5 CAR22469.1 - 3.2 7.8 6.6 3.6 7.5 0.1 2.8 3 0 0 3 3 3 0 Adhesion protein FadA DUF972 PF06156.8 CAR22469.1 - 3.5 8.0 9.3 1.6 9.0 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF745 PF05335.8 CAR22469.1 - 9.1 5.7 15.3 0.37 10.2 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF16 PF01519.11 CAR22469.1 - 9.8 6.4 7.5 1.8 8.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Snf7 PF03357.16 CAR22470.1 - 2.9e-50 169.9 13.3 2.9e-50 169.9 9.2 2.0 2 0 0 2 2 2 1 Snf7 Ribosomal_60s PF00428.14 CAR22470.1 - 0.0039 17.5 7.8 0.0039 17.5 5.4 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Cupin_8 PF13621.1 CAR22470.1 - 0.39 10.1 2.5 0.54 9.7 1.8 1.4 1 1 0 1 1 1 0 Cupin-like domain Cytomega_UL84 PF06284.6 CAR22470.1 - 0.42 8.9 6.1 0.09 11.1 0.8 1.9 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein Hydant_A_N PF05378.8 CAR22470.1 - 0.56 9.6 5.0 5.9 6.3 3.4 2.2 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Snapin_Pallidin PF14712.1 CAR22470.1 - 0.99 9.7 10.2 1.1 9.6 4.8 2.3 1 1 0 2 2 2 0 Snapin/Pallidin NPV_P10 PF05531.7 CAR22470.1 - 2.1 8.6 7.9 24 5.2 1.7 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein NuA4 PF09340.5 CAR22470.1 - 2.4 7.8 5.1 0.93 9.1 0.9 2.4 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF1875 PF08961.5 CAR22471.1 - 0.0018 17.6 1.8 0.0022 17.3 0.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1875) CDC37_N PF03234.9 CAR22471.1 - 0.013 15.8 1.9 0.019 15.2 1.3 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DivIC PF04977.10 CAR22471.1 - 0.085 12.3 6.7 0.17 11.3 4.6 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 CAR22471.1 - 0.15 12.3 1.3 0.27 11.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Imm35 PF15581.1 CAR22471.1 - 0.16 11.9 0.2 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 35 DivIVA PF05103.8 CAR22471.1 - 0.21 11.6 6.5 0.15 12.1 3.3 1.6 1 1 0 1 1 1 0 DivIVA protein Herpes_UL25 PF01499.11 CAR22471.1 - 1 7.5 6.9 1.2 7.3 4.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3280 PF11684.3 CAR22471.1 - 7.4 6.7 9.1 0.79 9.9 3.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2380) Sdh_cyt PF01127.17 CAR22472.1 - 2.9e-26 91.6 4.0 3.6e-26 91.3 2.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Abhydrolase_1 PF00561.15 CAR22473.1 - 7.9e-22 77.9 0.1 1.1e-21 77.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CAR22473.1 - 1.5e-19 69.1 0.2 2.6e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CAR22473.1 - 1.3e-06 28.4 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR22473.1 - 0.0005 19.8 0.0 0.0053 16.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CAR22473.1 - 0.021 14.2 0.0 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CAR22473.1 - 0.091 12.1 0.0 8 5.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1140 PF06600.6 CAR22473.1 - 0.19 11.8 1.8 2.2 8.4 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1140) Pkinase PF00069.20 CAR22474.1 - 1.6e-72 243.8 0.0 2e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22474.1 - 7.3e-33 113.7 0.0 9.7e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR22474.1 - 1.9e-05 23.7 0.0 5.1e-05 22.3 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR22474.1 - 0.0031 16.5 0.1 0.0079 15.2 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR22474.1 - 0.029 14.1 0.0 0.083 12.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Spc24 PF08286.6 CAR22475.1 - 3.8e-18 65.2 8.9 6.6e-18 64.5 0.1 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 OmpH PF03938.9 CAR22475.1 - 0.0082 16.0 5.5 0.015 15.2 3.8 1.4 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 CAR22475.1 - 0.016 14.3 6.0 0.02 14.1 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bul1_C PF04426.7 CAR22475.1 - 0.077 12.1 2.5 0.092 11.9 1.4 1.3 1 1 0 1 1 1 0 Bul1 C terminus ING PF12998.2 CAR22475.1 - 0.086 13.1 5.6 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DARPP-32 PF05395.7 CAR22475.1 - 0.2 11.8 5.2 0.28 11.3 3.6 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF342 PF03961.8 CAR22475.1 - 0.21 9.9 7.1 0.26 9.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FliJ PF02050.11 CAR22475.1 - 0.21 11.6 9.8 0.85 9.6 6.1 2.2 1 1 0 1 1 1 0 Flagellar FliJ protein NPV_P10 PF05531.7 CAR22475.1 - 0.22 11.8 2.9 2.4 8.4 0.3 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MSA_2 PF00985.12 CAR22475.1 - 0.24 11.5 1.8 0.28 11.2 0.2 1.8 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family Dor1 PF04124.7 CAR22475.1 - 0.28 9.5 5.7 0.39 9.1 4.0 1.2 1 0 0 1 1 1 0 Dor1-like family DUF1311 PF07007.7 CAR22475.1 - 0.48 10.5 3.2 0.3 11.1 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) Baculo_PEP_C PF04513.7 CAR22475.1 - 0.64 9.8 6.4 4.1 7.2 1.6 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF919 PF06034.6 CAR22475.1 - 1.2 8.7 6.9 8.2 6.1 0.6 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Sas10_Utp3 PF04000.10 CAR22475.1 - 1.2 9.3 7.0 6.4 7.0 1.4 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DUF4407 PF14362.1 CAR22475.1 - 2 7.2 5.7 2.6 6.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4164 PF13747.1 CAR22475.1 - 3.5 7.8 14.5 0.65 10.1 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Phage_GPO PF05929.6 CAR22475.1 - 4.8 6.3 6.8 0.69 9.1 1.1 1.8 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3552 PF12072.3 CAR22475.1 - 5.7 6.0 18.3 0.77 8.9 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) RP-C_C PF11800.3 CAR22475.1 - 5.9 6.5 10.4 6.2e+02 -0.1 7.2 2.1 1 1 0 1 1 1 0 Replication protein C C-terminal region Uds1 PF15456.1 CAR22475.1 - 8.6 6.3 13.2 2.3 8.2 1.1 2.3 1 1 1 2 2 2 0 Up-regulated During Septation L31 PF09784.4 CAR22476.1 - 3.5e-40 136.2 2.1 5.8e-40 135.5 1.5 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cmc1 PF08583.5 CAR22477.1 - 1.3e-18 66.5 2.3 2e-18 65.8 1.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CAR22477.1 - 0.061 13.2 0.7 0.21 11.5 0.4 2.0 1 1 0 1 1 1 0 CHCH domain Adaptin_N PF01602.15 CAR22478.1 - 2e-130 435.6 16.8 2.4e-130 435.3 11.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CAR22478.1 - 2.3e-23 82.9 1.4 2.3e-23 82.9 1.0 3.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CAR22478.1 - 5.5e-13 48.9 2.3 1.4e-07 31.7 0.1 5.1 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 CAR22478.1 - 6.2e-10 38.3 3.0 0.011 15.6 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 CAR22478.1 - 0.0013 19.1 8.6 0.56 10.7 0.1 5.4 7 0 0 7 7 7 2 HEAT-like repeat Arm_2 PF04826.8 CAR22478.1 - 0.019 14.1 3.9 0.019 14.0 0.5 2.5 2 2 0 2 2 2 0 Armadillo-like Arm PF00514.18 CAR22478.1 - 0.073 12.9 1.9 1.2 9.0 0.2 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 CAR22478.1 - 0.075 12.9 4.8 0.22 11.4 0.1 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2435) Gene66 PF02053.10 CAR22478.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Gene 66 (IR5) protein WD40 PF00400.27 CAR22479.1 - 1.1e-59 196.2 8.7 7.5e-10 38.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CAR22479.1 - 1e-06 28.6 3.5 3.1e-06 27.0 0.1 2.8 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CAR22479.1 - 3.6e-05 22.1 8.0 0.021 12.9 0.7 4.0 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR22479.1 - 0.013 14.2 0.1 4.3 5.9 0.0 2.8 1 1 0 3 3 3 0 Nup133 N terminal like DUF1513 PF07433.6 CAR22479.1 - 0.044 12.6 0.1 0.29 10.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) Polysacc_synt_2 PF02719.10 CAR22479.1 - 0.12 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Hydant_A_N PF05378.8 CAR22480.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region TPP_enzyme_N PF02776.13 CAR22481.1 - 7.9e-57 191.4 0.3 2.3e-56 189.9 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAR22481.1 - 4.6e-52 175.6 0.1 2.2e-50 170.2 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR22481.1 - 7.5e-37 126.1 0.4 2.6e-36 124.4 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 CAR22481.1 - 0.0044 16.5 0.1 0.0082 15.6 0.1 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Birna_VP4 PF01768.11 CAR22481.1 - 0.047 12.7 0.1 0.084 11.9 0.1 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein Myosin_head PF00063.16 CAR22482.1 - 6.7e-223 741.6 6.0 1.1e-222 740.9 4.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CAR22482.1 - 1.3e-49 168.2 0.1 5.4e-49 166.1 0.0 2.0 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 CAR22482.1 - 1.2e-11 43.7 0.0 2.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR22482.1 - 1.1e-08 34.4 0.0 2.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR22482.1 - 5.4e-06 25.7 0.0 1.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 CAR22482.1 - 0.0049 17.0 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR22482.1 - 0.016 14.3 0.0 0.047 12.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CAR22482.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Hpr_kinase_C PF07475.7 CAR22482.1 - 0.039 13.2 0.1 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 CAR22482.1 - 0.044 14.5 0.0 0.19 12.5 0.0 2.2 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 CAR22482.1 - 0.053 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SH3_3 PF08239.6 CAR22482.1 - 0.074 13.2 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 Bacterial SH3 domain NACHT PF05729.7 CAR22482.1 - 0.086 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CAR22482.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Aldedh PF00171.17 CAR22483.1 - 1.6e-71 241.0 0.0 1.9e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4092 PF13322.1 CAR22483.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) She2p PF11435.3 CAR22484.1 - 3.5e-83 278.0 7.7 4.4e-83 277.6 5.4 1.1 1 0 0 1 1 1 1 RNA binding protein She2p Glyco_hydro_4C PF11975.3 CAR22484.1 - 0.016 14.9 0.1 0.034 13.9 0.0 1.5 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain RasGAP_C PF03836.10 CAR22484.1 - 0.059 13.0 0.8 9.1 5.9 0.3 2.5 2 0 0 2 2 2 0 RasGAP C-terminus GCR1_C PF12550.3 CAR22485.1 - 9.7e-23 79.8 0.0 1.8e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes PAS PF00989.19 CAR22485.1 - 0.0016 18.2 0.4 0.011 15.4 0.1 2.5 3 0 0 3 3 3 1 PAS fold DUF977 PF06163.6 CAR22485.1 - 0.038 13.7 0.2 0.091 12.5 0.1 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) DivIC PF04977.10 CAR22485.1 - 0.089 12.2 1.2 0.92 9.0 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator Med11 PF10280.4 CAR22486.1 - 8.6e-23 80.6 1.4 9.5e-23 80.4 1.0 1.0 1 0 0 1 1 1 1 Mediator complex protein DUF904 PF06005.7 CAR22486.1 - 0.013 15.7 2.7 0.83 9.9 1.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Mer2 PF09074.5 CAR22486.1 - 0.02 14.8 0.7 0.023 14.6 0.5 1.1 1 0 0 1 1 1 0 Mer2 NEMO PF11577.3 CAR22486.1 - 0.076 12.7 6.3 0.53 10.0 0.1 2.9 2 1 1 3 3 3 0 NF-kappa-B essential modulator NEMO Mur_ligase_M PF08245.7 CAR22487.1 - 1.2e-09 38.5 0.2 2.3e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CAR22487.1 - 0.065 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF159 PF02586.9 CAR22488.1 - 1.8e-59 200.7 0.8 3.1e-59 199.9 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 PBP_sp32 PF07222.7 CAR22488.1 - 1.6 7.8 7.1 2.2 7.3 4.9 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TPR_12 PF13424.1 CAR22489.1 - 0.00036 20.3 4.4 0.047 13.6 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR22489.1 - 0.15 12.7 0.9 37 5.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAR22489.1 - 0.24 11.4 5.6 11 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M3 PF01432.15 CAR22490.1 - 6.8e-129 430.8 0.0 8.7e-129 430.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 ADSL_C PF10397.4 CAR22490.1 - 0.081 12.9 0.5 18 5.4 0.0 3.7 4 0 0 4 4 4 0 Adenylosuccinate lyase C-terminus Peptidase_M50B PF13398.1 CAR22490.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Ku PF02735.11 CAR22491.1 - 3.8e-29 101.5 0.0 6.2e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CAR22491.1 - 1.5e-16 60.5 0.0 2.2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain zf-CpG_bind_C PF12269.3 CAR22491.1 - 0.39 10.1 2.3 0.21 11.0 0.2 1.5 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain PGM_PMM_I PF02878.11 CAR22492.1 - 4.3e-34 116.9 0.1 7.1e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CAR22492.1 - 3.1e-25 88.4 0.0 6e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CAR22492.1 - 3.3e-14 53.0 0.1 1.2e-13 51.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CAR22492.1 - 1.4e-08 34.6 0.0 3.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fer4_12 PF13353.1 CAR22492.1 - 0.036 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Pkinase PF00069.20 CAR22493.1 - 2.1e-70 236.8 0.0 3.1e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22493.1 - 2.8e-32 111.8 0.0 3.9e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CAR22493.1 - 3.8e-09 36.9 0.6 3.8e-09 36.9 0.4 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR22493.1 - 0.00019 20.4 0.0 0.00074 18.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR22493.1 - 0.032 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR22493.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRN3 PF05327.6 CAR22494.1 - 1.7e-184 614.0 10.9 2e-184 613.8 7.6 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Matrilin_ccoil PF10393.4 CAR22494.1 - 0.097 12.0 0.2 0.36 10.2 0.1 2.0 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-MYND PF01753.13 CAR22495.1 - 2.2e-07 30.6 19.8 8.2e-07 28.8 13.7 2.0 1 1 0 1 1 1 1 MYND finger Vma12 PF11712.3 CAR22496.1 - 2.5e-37 127.7 0.1 4e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4149 PF13664.1 CAR22496.1 - 0.032 14.2 0.1 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Prenyltransf PF01255.14 CAR22497.1 - 6.7e-69 231.4 0.0 8.9e-69 231.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Mito_carr PF00153.22 CAR22498.1 - 2.7e-61 203.2 5.3 1.2e-20 73.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 CAR22499.1 - 3e-26 90.3 5.8 2.7e-07 30.2 0.0 5.5 7 0 0 7 7 7 3 WD domain, G-beta repeat IKI3 PF04762.7 CAR22499.1 - 0.068 10.9 0.1 7.4 4.2 0.0 2.2 1 1 0 2 2 2 0 IKI3 family Cytochrom_D1 PF02239.11 CAR22499.1 - 0.075 11.3 0.0 1.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain zf-piccolo PF05715.8 CAR22499.1 - 0.17 11.8 3.0 0.33 10.9 0.7 2.2 2 0 0 2 2 2 0 Piccolo Zn-finger SRP9-21 PF05486.7 CAR22500.1 - 3.3e-21 74.8 0.2 4.5e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) SPRY PF00622.23 CAR22501.1 - 2.1e-11 43.9 0.0 4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF3827 PF12877.2 CAR22501.1 - 0.19 9.8 0.8 0.22 9.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) CS PF04969.11 CAR22502.1 - 0.041 14.4 0.1 0.083 13.4 0.0 1.7 1 1 0 1 1 1 0 CS domain AntA PF08346.7 CAR22502.1 - 0.05 13.8 0.1 12 6.1 0.0 2.4 2 0 0 2 2 2 0 AntA/AntB antirepressor PM0188 PF11477.3 CAR22502.1 - 0.15 10.8 0.6 0.2 10.4 0.4 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 Aldose_epim PF01263.15 CAR22503.1 - 5.6e-44 150.4 0.1 6.8e-44 150.1 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.20 CAR22504.1 - 8e-53 179.2 0.0 1.1e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22504.1 - 2.3e-19 69.5 0.0 2.5e-18 66.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AP_endonuc_2 PF01261.19 CAR22505.1 - 2.3e-32 112.0 0.0 3.1e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HpaB_N PF11794.3 CAR22505.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal XPG_N PF00752.12 CAR22506.1 - 5.1e-38 129.4 0.0 9.8e-38 128.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CAR22506.1 - 2.4e-26 91.5 0.0 5e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CAR22506.1 - 1.6e-06 28.2 0.1 1.3e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 CAR22506.1 - 0.046 13.8 0.0 0.34 11.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.2 CAR22506.1 - 0.061 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif BAF1_ABF1 PF04684.8 CAR22507.1 - 6.2e-120 401.3 17.9 1.3e-66 225.4 0.1 5.2 2 1 3 5 5 5 4 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 CAR22507.1 - 0.00033 20.1 0.1 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 MuDR family transposase SelP_N PF04592.9 CAR22507.1 - 0.91 8.8 23.3 2.2 7.6 16.1 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PKI PF02827.11 CAR22507.1 - 1 9.5 4.6 2.3 8.4 3.2 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF1387 PF07139.6 CAR22507.1 - 3 7.3 10.0 5.6 6.4 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF4557 PF15101.1 CAR22507.1 - 5.3 6.8 15.4 12 5.6 8.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4557) LMBR1 PF04791.11 CAR22507.1 - 6.7 5.1 5.1 9.7 4.6 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein mRNA_stabil PF13929.1 CAR22508.1 - 4.2e-107 357.4 0.0 6.2e-107 356.9 0.0 1.3 1 0 0 1 1 1 1 mRNA stabilisation Oligomerisation PF02410.10 CAR22508.1 - 2.8e-16 59.3 0.0 9.6e-16 57.6 0.0 1.9 2 0 0 2 2 2 1 Oligomerisation domain KTI12 PF08433.5 CAR22509.1 - 6.4e-94 314.1 0.6 7.3e-94 313.9 0.4 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CAR22509.1 - 8.1e-05 22.5 0.0 0.00026 20.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR22509.1 - 0.00049 20.4 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR22509.1 - 0.0026 18.5 0.0 0.0061 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR22509.1 - 0.0066 16.5 0.1 0.089 12.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR22509.1 - 0.02 14.8 0.3 0.68 9.8 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain DUF3582 PF12122.3 CAR22509.1 - 0.029 14.3 0.2 0.69 9.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3582) AAA PF00004.24 CAR22509.1 - 0.041 14.0 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 CAR22509.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CDC48_N PF02359.13 CAR22509.1 - 0.055 13.4 0.7 3.5 7.6 0.2 2.4 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Elong_Iki1 PF10483.4 CAR22509.1 - 0.066 12.5 0.4 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Elongator subunit Iki1 Mob_Pre PF01076.14 CAR22509.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Plasmid recombination enzyme MMR_HSR1 PF01926.18 CAR22510.1 - 3.9e-11 42.9 0.0 9.5e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR22510.1 - 0.00011 21.3 0.3 0.00034 19.8 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR22510.1 - 0.0054 16.1 0.2 0.023 14.1 0.1 1.9 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 CAR22510.1 - 0.0098 15.1 0.2 0.032 13.5 0.1 1.8 1 1 1 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR22510.1 - 0.059 13.1 0.1 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Dynamin family KaiC PF06745.8 CAR22510.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 KaiC ArgK PF03308.11 CAR22510.1 - 0.081 11.6 1.2 0.98 8.1 0.1 2.2 1 1 1 2 2 2 0 ArgK protein AAA_18 PF13238.1 CAR22510.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CAR22510.1 - 0.17 11.6 0.1 0.78 9.4 0.0 2.0 2 0 0 2 2 2 0 NTPase Hap4_Hap_bind PF10297.4 CAR22511.1 - 2.2e-08 33.6 8.9 6.1e-08 32.2 6.1 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Herpes_BLRF2 PF05812.7 CAR22511.1 - 0.0092 15.7 0.8 0.021 14.6 0.5 1.6 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Golgin_A5 PF09787.4 CAR22511.1 - 0.021 13.3 10.0 0.045 12.2 6.9 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 DivIC PF04977.10 CAR22511.1 - 0.13 11.7 1.3 0.27 10.7 0.9 1.5 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.8 CAR22511.1 - 0.15 11.9 9.1 0.25 11.1 6.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOR_SNZ PF01680.12 CAR22512.1 - 4.6e-105 349.7 8.3 6e-105 349.4 5.8 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 CAR22512.1 - 3.2e-08 32.9 2.2 4.5e-07 29.2 0.0 2.5 2 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 CAR22512.1 - 0.00014 20.8 1.1 0.3 9.8 0.0 3.0 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CAR22512.1 - 0.0016 17.7 0.1 0.026 13.7 0.0 2.5 3 0 0 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 CAR22512.1 - 0.01 15.0 0.8 0.034 13.3 0.0 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase NanE PF04131.9 CAR22512.1 - 0.016 14.1 0.2 0.15 11.0 0.0 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 CAR22512.1 - 0.023 13.7 0.1 0.058 12.4 0.0 1.8 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.12 CAR22512.1 - 0.047 12.8 1.5 0.44 9.6 0.0 2.8 2 2 1 3 3 3 0 Thiamine monophosphate synthase/TENI SNO PF01174.14 CAR22513.1 - 3.9e-67 225.5 0.0 5.2e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 CAR22513.1 - 2.3e-08 33.7 0.0 8.2e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 CAR22513.1 - 0.00085 18.8 0.0 0.0047 16.4 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 CAR22513.1 - 0.0042 16.3 0.1 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase ArsD PF06953.6 CAR22513.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD DJ-1_PfpI PF01965.19 CAR22513.1 - 0.013 14.9 0.2 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.12 CAR22513.1 - 0.017 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 DUF4154 PF13689.1 CAR22513.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Peptidase_C26 PF07722.8 CAR22513.1 - 0.055 12.8 0.0 0.2 11.0 0.0 1.9 2 1 0 2 2 2 0 Peptidase C26 UPF0180 PF03698.8 CAR22513.1 - 0.06 13.1 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0180) GATase_5 PF13507.1 CAR22513.1 - 0.072 11.9 0.0 2.9 6.7 0.0 2.2 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Drc1-Sld2 PF11719.3 CAR22515.1 - 4.3e-48 164.4 24.7 2.1e-46 158.8 17.1 2.3 1 1 0 1 1 1 1 DNA replication and checkpoint protein UTP15_C PF09384.5 CAR22516.1 - 1.3e-50 170.8 0.5 1.9e-50 170.3 0.4 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CAR22516.1 - 3e-21 74.4 4.2 0.00017 21.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40 PF00400.27 CAR22517.1 - 5.3e-29 99.0 25.2 0.00013 21.7 0.3 11.7 11 1 0 11 11 11 7 WD domain, G-beta repeat Nup160 PF11715.3 CAR22517.1 - 0.0025 16.0 0.0 0.25 9.4 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CAR22517.1 - 0.13 11.9 0.8 13 5.3 0.0 3.9 5 1 1 6 6 6 0 Eukaryotic translation initiation factor eIF2A CRC_subunit PF08624.5 CAR22518.1 - 1.1e-57 193.7 0.0 2e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Nop14 PF04147.7 CAR22518.1 - 4.8 4.9 7.7 6.3 4.5 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M41 PF01434.13 CAR22519.1 - 6e-73 244.8 0.0 6e-73 244.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CAR22519.1 - 6.5e-43 146.1 0.0 1.9e-42 144.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CAR22519.1 - 6.9e-09 35.8 0.1 3.1e-08 33.7 0.1 2.1 1 1 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CAR22519.1 - 0.00013 22.7 0.9 0.00071 20.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CAR22519.1 - 0.001 18.8 0.1 0.0076 15.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CAR22519.1 - 0.0022 16.7 0.0 0.0043 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Fe-ADH_2 PF13685.1 CAR22519.1 - 0.0079 15.5 0.7 0.14 11.4 0.0 2.9 3 1 1 4 4 4 1 Iron-containing alcohol dehydrogenase AAA_22 PF13401.1 CAR22519.1 - 0.0087 16.1 0.0 0.46 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR22519.1 - 0.009 15.7 1.1 0.025 14.3 0.8 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CAR22519.1 - 0.0095 15.0 0.0 0.032 13.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus CARD PF00619.16 CAR22519.1 - 0.026 14.3 0.3 0.065 13.0 0.2 1.6 1 0 0 1 1 1 0 Caspase recruitment domain AAA_16 PF13191.1 CAR22519.1 - 0.042 13.8 0.1 0.15 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 CAR22519.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 CAR22519.1 - 0.3 10.4 2.5 0.45 9.8 0.3 2.4 2 1 1 3 3 3 0 AAA domain MFS_1 PF07690.11 CAR22520.1 - 5.9e-38 130.4 42.5 1e-37 129.7 27.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR22520.1 - 1.1e-13 50.6 11.6 1.1e-13 50.6 8.1 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter Macro_2 PF14519.1 CAR22521.1 - 3.5e-79 265.8 0.0 4.6e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 CAR22521.1 - 0.00014 21.7 0.0 0.00037 20.3 0.0 1.7 2 0 0 2 2 2 1 Macro domain Aminotran_1_2 PF00155.16 CAR22522.1 - 1.3e-83 281.0 0.0 1.4e-83 280.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SIS PF01380.17 CAR22524.1 - 2.1e-61 205.3 0.1 9.1e-32 109.4 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CAR22524.1 - 4.7e-32 111.0 0.0 3e-23 82.0 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CAR22524.1 - 3.2e-18 65.9 0.0 6.8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CAR22524.1 - 1.1e-11 44.5 0.0 2.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CAR22524.1 - 3e-09 35.9 0.1 5.2e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Peptidase_M18 PF02127.10 CAR22525.1 - 1.9e-140 468.1 0.0 2.3e-140 467.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pkinase PF00069.20 CAR22526.1 - 8.8e-71 238.0 0.0 1.6e-70 237.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22526.1 - 1.8e-37 128.7 0.0 3e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CAR22526.1 - 0.00055 19.5 0.1 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CAR22526.1 - 0.0014 18.4 0.0 0.0075 16.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR22526.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4407 PF14362.1 CAR22526.1 - 0.37 9.7 2.2 0.96 8.3 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADH_N PF08240.7 CAR22527.1 - 5.5e-30 103.3 0.5 1e-29 102.4 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR22527.1 - 5.6e-27 93.8 0.4 8.2e-27 93.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR22527.1 - 4.9e-07 30.6 0.1 1.1e-06 29.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Utp11 PF03998.8 CAR22529.1 - 2.2e-69 233.9 35.0 2.5e-69 233.7 24.2 1.0 1 0 0 1 1 1 1 Utp11 protein PIR PF00399.14 CAR22531.1 - 4.5e-37 124.1 74.1 8.4e-08 31.3 6.7 5.9 5 0 0 5 5 5 5 Yeast PIR protein repeat SBP_bac_7 PF03480.8 CAR22531.1 - 0.048 12.7 1.7 3.6 6.6 0.1 2.2 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Drf_FH1 PF06346.7 CAR22532.1 - 5.3 6.5 26.4 0.083 12.3 10.7 2.8 2 1 0 2 2 2 0 Formin Homology Region 1 DUF572 PF04502.8 CAR22533.1 - 2.3e-46 158.5 21.4 3.5e-46 157.9 14.8 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) Mu-like_Com PF10122.4 CAR22533.1 - 0.027 13.5 0.6 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com DUF106 PF01956.11 CAR22533.1 - 0.096 12.2 0.0 0.24 10.9 0.0 1.7 1 1 0 1 1 1 0 Integral membrane protein DUF106 APG6 PF04111.7 CAR22533.1 - 0.098 11.6 12.5 0.15 11.1 8.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Allexi_40kDa PF05549.6 CAR22533.1 - 0.18 11.0 3.3 0.33 10.2 2.3 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein zf-FPG_IleRS PF06827.9 CAR22533.1 - 0.24 11.1 1.5 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS EMP24_GP25L PF01105.19 CAR22533.1 - 1.7 8.3 6.1 0.32 10.6 1.6 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD LMBR1 PF04791.11 CAR22533.1 - 1.9 6.9 8.1 2.5 6.5 5.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.14 CAR22533.1 - 2.2 6.0 8.9 2.8 5.7 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 CAR22533.1 - 6.2 5.6 12.7 11 4.8 8.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tho2 PF11262.3 CAR22533.1 - 8.8 5.2 8.9 14 4.6 6.2 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Abhydrolase_1 PF00561.15 CAR22534.1 - 1e-22 80.8 0.0 1.3e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR22534.1 - 1.2e-21 77.6 0.0 1.4e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR22534.1 - 1.4e-21 76.7 0.0 1e-20 73.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CAR22534.1 - 1.3e-12 47.3 0.0 6e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CAR22534.1 - 0.0034 16.6 0.2 0.11 11.6 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 CAR22534.1 - 0.01 15.1 0.0 0.027 13.7 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family LCAT PF02450.10 CAR22534.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 CAR22534.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.11 CAR22534.1 - 0.046 13.1 0.0 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 CAR22534.1 - 0.071 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 CAR22534.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 CAR22534.1 - 0.14 11.5 0.0 0.67 9.3 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) UPF1_Zn_bind PF09416.5 CAR22536.1 - 5.9e-68 227.2 11.0 5.9e-68 227.2 7.6 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CAR22536.1 - 4.6e-59 199.1 0.0 8.5e-59 198.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR22536.1 - 4.4e-52 177.0 1.2 6.6e-52 176.4 0.9 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CAR22536.1 - 4.1e-14 52.6 0.0 3.2e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR22536.1 - 2.2e-13 49.7 0.1 5.8e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CAR22536.1 - 3.6e-06 26.1 0.2 2.3e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CAR22536.1 - 4.3e-05 23.4 0.0 7.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 CAR22536.1 - 0.00013 21.3 0.3 0.033 13.4 0.0 2.8 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 CAR22536.1 - 0.00017 21.1 0.0 0.44 10.0 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CAR22536.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Helicase DEAD PF00270.24 CAR22536.1 - 0.0043 16.5 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 CAR22536.1 - 0.0085 15.0 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase PhoH PF02562.11 CAR22536.1 - 0.011 15.0 0.0 0.024 13.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein HEM4 PF02602.10 CAR22536.1 - 0.03 13.5 0.1 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD T2SE PF00437.15 CAR22536.1 - 0.03 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 CAR22536.1 - 0.044 13.7 0.3 0.08 12.9 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S13_N PF08069.7 CAR22536.1 - 0.091 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 CAR22536.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RasGAP PF00616.14 CAR22537.1 - 1.5e-45 155.3 2.5 2.9e-45 154.3 1.7 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 CAR22537.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain CRAL_TRIO PF00650.15 CAR22538.1 - 1.4e-36 125.3 0.0 1.8e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CAR22538.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.3 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain AAA PF00004.24 CAR22539.1 - 3.1e-11 43.5 0.0 8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAR22539.1 - 2.8e-09 36.2 0.2 0.00012 20.9 0.0 3.0 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CAR22539.1 - 5.3e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR22539.1 - 8.5e-05 23.3 0.0 0.00032 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR22539.1 - 0.00019 21.5 0.1 0.0035 17.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR22539.1 - 0.00034 19.7 0.0 0.00096 18.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CAR22539.1 - 0.00038 20.1 0.0 0.0026 17.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain DNA_pol3_delta PF06144.8 CAR22539.1 - 0.0021 17.5 0.4 0.0045 16.5 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 CAR22539.1 - 0.0031 17.5 0.1 0.021 14.8 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 CAR22539.1 - 0.0055 16.5 0.1 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAR22539.1 - 0.016 14.3 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CAR22539.1 - 0.024 14.9 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CAR22539.1 - 0.044 13.5 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IPT PF01745.11 CAR22539.1 - 0.047 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase bZIP_1 PF00170.16 CAR22540.1 - 1.1e-05 25.2 17.2 1.1e-05 25.2 11.9 2.0 2 0 0 2 2 2 1 bZIP transcription factor Pinin_SDK_memA PF04696.8 CAR22540.1 - 0.0021 17.6 9.7 0.0034 16.9 6.7 1.2 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region CCDC155 PF14662.1 CAR22540.1 - 0.0055 16.3 9.0 0.0097 15.5 6.3 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 bZIP_2 PF07716.10 CAR22540.1 - 0.01 15.6 17.0 0.01 15.6 11.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper dsrm PF00035.20 CAR22540.1 - 0.1 13.1 0.7 0.94 10.1 0.3 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF972 PF06156.8 CAR22540.1 - 1.2 9.5 7.5 1.5 9.2 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Metal_resist PF13801.1 CAR22540.1 - 1.9 8.5 8.7 3.1 7.7 6.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance 2OG-FeII_Oxy_3 PF13640.1 CAR22541.1 - 7.3e-10 39.2 0.1 1.2e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CAR22541.1 - 0.001 18.6 0.1 0.0026 17.3 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CAR22541.1 - 0.004 17.4 0.1 0.0065 16.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3440 PF11922.3 CAR22541.1 - 0.035 13.6 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Sod_Fe_N PF00081.17 CAR22541.1 - 0.051 13.8 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF4299 PF14132.1 CAR22541.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) ATPgrasp_YheCD PF14398.1 CAR22541.1 - 0.12 11.2 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp Smr PF01713.16 CAR22542.1 - 1.4e-11 44.3 0.0 3.1e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CAR22542.1 - 8.3e-05 21.9 0.0 0.0032 16.9 0.0 2.4 2 0 0 2 2 2 1 CUE domain CENP-C_C PF11699.3 CAR22543.1 - 9.9e-26 89.5 0.2 1.7e-25 88.8 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 CAR22543.1 - 3.7e-20 72.9 1.8 3.7e-20 72.9 1.2 3.7 3 0 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 CAR22543.1 - 7.9e-06 25.2 0.0 1.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Cupin domain AT_hook PF02178.14 CAR22543.1 - 0.052 13.2 5.5 0.2 11.4 3.8 2.1 1 0 0 1 1 1 0 AT hook motif Selenoprotein_S PF06936.6 CAR22543.1 - 0.35 10.3 4.8 0.65 9.5 1.3 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) Pkinase PF00069.20 CAR22544.1 - 8.2e-72 241.4 0.0 1.4e-71 240.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22544.1 - 2.8e-46 157.6 0.0 4.9e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CAR22544.1 - 4.1e-23 81.5 0.1 1.9e-22 79.3 0.1 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 CAR22544.1 - 4.1e-05 22.6 0.0 7.2e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR22544.1 - 0.17 11.5 0.0 1.8 8.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.20 CAR22545.1 - 1.1e-72 244.9 1.0 1.9e-72 244.0 0.7 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L10 PF00466.15 CAR22546.1 - 5e-16 58.4 0.0 7.2e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3538 PF12057.3 CAR22546.1 - 0.049 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) PT-VENN PF04829.8 CAR22546.1 - 0.14 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Ribosomal_S2 PF00318.15 CAR22548.1 - 1.4e-61 207.4 0.0 2.8e-61 206.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 TRAM_LAG1_CLN8 PF03798.11 CAR22549.1 - 4.5e-36 124.2 24.1 4.5e-36 124.2 16.7 2.0 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CAR22549.1 - 2.4e-24 84.5 0.1 6.7e-24 83.1 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein DUF4365 PF14280.1 CAR22549.1 - 0.028 14.1 1.2 1.4 8.5 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4365) Herpes_LMP1 PF05297.6 CAR22549.1 - 0.45 9.3 5.0 0.68 8.8 3.5 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VHS PF00790.14 CAR22550.1 - 1.2e-31 109.2 0.2 2.8e-31 108.0 0.1 1.7 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 CAR22550.1 - 4.4e-16 57.9 0.0 8.3e-16 57.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR22550.1 - 9.1e-16 57.1 0.0 1.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR22550.1 - 8.8e-14 50.7 0.3 3.9e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain Hrs_helical PF12210.3 CAR22550.1 - 0.004 17.3 5.0 0.012 15.8 0.1 2.8 2 1 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Tnp_DNA_bind PF14706.1 CAR22550.1 - 0.043 13.5 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Transposase DNA-binding F-actin_cap_A PF01267.12 CAR22551.1 - 5e-79 265.1 0.8 5.7e-79 264.9 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF925 PF06042.6 CAR22551.1 - 0.019 14.5 0.3 0.05 13.1 0.1 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF925) HOOK PF05622.7 CAR22552.1 - 0.028 12.2 0.7 0.033 12.0 0.5 1.0 1 0 0 1 1 1 0 HOOK protein SNARE PF05739.14 CAR22552.1 - 0.04 13.5 2.8 0.048 13.3 2.0 1.1 1 0 0 1 1 1 0 SNARE domain Syntaxin PF00804.20 CAR22552.1 - 0.084 13.0 0.2 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Syntaxin Cadherin PF00028.12 CAR22552.1 - 0.11 12.8 0.1 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Cadherin domain DUF4492 PF14899.1 CAR22552.1 - 0.12 11.8 0.8 0.25 10.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Ribosomal_L14e PF01929.12 CAR22553.1 - 1.1e-31 108.9 0.6 1.7e-31 108.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CAR22553.1 - 5.8e-05 22.6 0.1 0.00013 21.5 0.1 1.6 1 0 0 1 1 1 1 KOW motif TFIIS_M PF07500.9 CAR22554.1 - 1.1e-16 60.9 0.5 1.1e-16 60.9 0.4 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 CAR22554.1 - 4.8e-10 38.9 8.7 1.1e-09 37.7 6.0 1.7 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 CAR22554.1 - 2.6e-07 31.1 0.0 6.7e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 SPOC domain zf-CW PF07496.10 CAR22554.1 - 0.0072 16.0 7.0 0.011 15.4 1.5 2.9 3 0 0 3 3 3 1 CW-type Zinc Finger Elf1 PF05129.8 CAR22554.1 - 1.8 8.3 6.4 1.9 8.2 1.7 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like PAP2 PF01569.16 CAR22555.1 - 2.2e-13 49.9 3.8 2.2e-13 49.9 2.7 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CAR22555.1 - 0.00065 19.2 4.1 0.00065 19.2 2.9 2.1 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_S6 PF01250.12 CAR22556.1 - 8.4e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Snf7 PF03357.16 CAR22557.1 - 3.5e-33 114.3 21.2 3.5e-33 114.3 14.7 1.8 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 CAR22557.1 - 7e-07 28.8 8.0 9.6e-07 28.3 5.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway HrpB7 PF09486.5 CAR22557.1 - 0.048 13.5 9.5 0.62 9.9 4.3 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Remorin_C PF03763.8 CAR22557.1 - 0.16 11.5 11.1 0.32 10.5 7.7 1.6 1 0 0 1 1 1 0 Remorin, C-terminal region YlqD PF11068.3 CAR22557.1 - 1.3 9.0 20.4 2.2 8.3 8.5 2.2 1 1 1 2 2 2 0 YlqD protein Prefoldin_2 PF01920.15 CAR22557.1 - 2.1 8.1 14.2 3.1 7.6 1.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 CAR22557.1 - 2.8 5.6 7.7 3.6 5.3 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 CAR22557.1 - 4.7 6.9 8.2 3.1 7.5 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF87 KxDL PF10241.4 CAR22557.1 - 5.3 7.0 11.6 3.7 7.5 0.1 3.3 2 1 0 3 3 3 0 Uncharacterized conserved protein DUF1002 PF06207.6 CAR22557.1 - 5.6 6.2 11.8 0.66 9.2 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) 4F5 PF04419.9 CAR22557.1 - 6.1 7.6 8.0 14 6.4 3.2 2.7 2 0 0 2 2 2 0 4F5 protein family APS_kinase PF01583.15 CAR22558.1 - 6e-72 240.4 0.0 7.1e-72 240.1 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CAR22558.1 - 3.7e-07 30.1 0.0 7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR22558.1 - 1.9e-05 25.4 0.0 2.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CAR22558.1 - 4.8e-05 22.8 0.0 7.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CAR22558.1 - 8.2e-05 22.9 0.1 0.00025 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CAR22558.1 - 0.00025 20.3 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 CAR22558.1 - 0.015 14.9 1.0 0.39 10.3 0.7 2.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 CAR22558.1 - 0.027 14.8 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CAR22558.1 - 0.033 14.1 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 CAR22558.1 - 0.036 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 CAR22558.1 - 0.042 14.1 0.0 0.072 13.3 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 CAR22558.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Dynamin_M PF01031.15 CAR22559.1 - 1.1e-105 352.7 0.1 1.9e-105 351.9 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CAR22559.1 - 9.1e-57 191.5 0.1 2.1e-56 190.3 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CAR22559.1 - 5.4e-26 90.3 3.8 5.4e-26 90.3 2.6 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CAR22559.1 - 0.0027 17.6 3.0 0.0063 16.4 0.5 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CAR22559.1 - 0.035 14.5 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein PAP_central PF04928.12 CAR22560.1 - 1e-109 365.2 0.0 1.6e-109 364.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CAR22560.1 - 3.4e-47 159.8 0.1 6.5e-47 158.9 0.1 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CAR22560.1 - 3.3e-11 43.3 0.0 9.6e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.13 CAR22560.1 - 0.072 12.8 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 Oxysterol_BP PF01237.13 CAR22561.1 - 2.2e-91 305.9 0.0 2.8e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PPTA PF01239.17 CAR22562.1 - 0.0022 17.2 4.2 0.79 9.1 0.6 3.7 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat Ribosomal_L50 PF10501.4 CAR22563.1 - 1.4e-18 66.9 0.0 6.6e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal subunit 39S PaREP1 PF05942.6 CAR22563.1 - 0.035 13.9 2.0 1.4 8.7 0.7 2.7 2 1 1 3 3 3 0 Archaeal PaREP1/PaREP8 family LAMTOR PF15454.1 CAR22564.1 - 5.9e-14 52.1 3.4 8.3e-14 51.6 2.4 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF3552 PF12072.3 CAR22564.1 - 0.012 14.8 0.7 0.017 14.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2733 PF10813.3 CAR22564.1 - 0.091 12.3 1.1 0.21 11.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) Bromodomain PF00439.20 CAR22565.1 - 2e-28 98.1 3.8 9e-18 63.9 0.2 2.5 2 0 0 2 2 2 2 Bromodomain QCR10 PF09796.4 CAR22566.1 - 1.6e-29 101.3 0.2 1.9e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 CAR22566.1 - 0.021 14.5 0.1 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein adh_short PF00106.20 CAR22567.1 - 4.5e-65 218.6 4.2 3.5e-32 111.6 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CAR22567.1 - 8.8e-31 106.9 1.2 4.7e-15 55.7 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CAR22567.1 - 8.9e-31 105.8 0.0 1.8e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 CAR22567.1 - 1.7e-21 77.1 0.2 1.6e-09 37.8 0.0 2.6 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 CAR22567.1 - 0.035 13.7 4.3 2.3 7.8 0.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CAR22567.1 - 0.42 10.8 3.0 9.4 6.5 0.1 3.3 3 0 0 3 3 3 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 CAR22567.1 - 0.44 10.3 3.0 0.78 9.5 0.1 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DAO PF01266.19 CAR22567.1 - 1.2 8.0 4.3 1.5 7.6 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Adap_comp_sub PF00928.16 CAR22568.1 - 4.5e-37 127.5 0.0 6.1e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family SNF5 PF04855.7 CAR22569.1 - 3.5e-62 210.0 4.3 3.5e-62 210.0 3.0 4.2 2 2 1 3 3 3 1 SNF5 / SMARCB1 / INI1 Caldesmon PF02029.10 CAR22569.1 - 0.00011 20.7 16.6 0.00016 20.2 11.5 1.3 1 0 0 1 1 1 1 Caldesmon PLRV_ORF5 PF01690.12 CAR22569.1 - 4.6 6.2 42.6 7.5 5.5 29.5 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2370 PF10176.4 CAR22570.1 - 1.6e-76 256.7 0.0 1.9e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.22 CAR22571.1 - 2.1e-64 213.2 2.0 2.4e-22 78.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CAR22571.1 - 0.0045 17.0 0.2 6.1 6.9 0.0 2.9 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.22 CAR22572.1 - 2.4e-59 197.0 0.7 2.5e-20 71.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.2 CAR22572.1 - 0.01 15.6 3.1 0.93 9.3 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) ThiF PF00899.16 CAR22573.1 - 3.9e-37 127.1 0.0 6.2e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CAR22573.1 - 0.00042 20.4 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CAR22573.1 - 0.0034 16.4 0.4 0.0055 15.7 0.3 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 CAR22573.1 - 0.028 14.4 0.1 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 CAR22573.1 - 0.033 14.4 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.19 CAR22573.1 - 0.078 11.8 0.2 0.16 10.8 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 CAR22573.1 - 0.088 12.1 0.4 0.15 11.3 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 CAR22573.1 - 0.09 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TFIIE_alpha PF02002.12 CAR22574.1 - 1e-28 98.9 0.1 2.8e-28 97.4 0.0 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 CAR22574.1 - 9.8e-09 34.4 0.2 9.8e-09 34.4 0.1 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding DUF2197 PF09963.4 CAR22574.1 - 0.24 11.3 1.4 32 4.5 0.1 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF2951 PF11166.3 CAR22574.1 - 5.7 6.8 10.1 8.8 6.2 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) MFS_1 PF07690.11 CAR22575.1 - 1.9e-32 112.3 27.5 6.3e-32 110.6 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR22575.1 - 2.4e-16 59.3 28.9 4.7e-14 51.8 6.3 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Malic_M PF03949.10 CAR22576.1 - 2.7e-77 259.8 0.1 5e-77 258.8 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CAR22576.1 - 9.1e-62 207.8 0.0 2.7e-61 206.3 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain OPT PF03169.10 CAR22577.1 - 1.2e-154 516.2 45.0 1.4e-154 515.9 31.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NIF PF03031.13 CAR22578.1 - 3.3e-51 173.0 0.0 4.6e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-H2C2_2 PF13465.1 CAR22579.1 - 6.6e-11 41.9 6.4 9.1e-07 28.8 0.1 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CAR22579.1 - 1.9e-10 40.4 11.5 6.6e-06 26.1 0.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR22579.1 - 1.3e-09 37.7 9.3 1.7e-05 24.7 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CAR22579.1 - 0.0066 16.3 0.5 0.0066 16.3 0.4 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 CAR22579.1 - 0.014 15.5 0.4 0.014 15.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.1 CAR22579.1 - 0.11 12.0 1.2 4 7.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAR22579.1 - 0.11 12.1 1.1 3.5 7.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CAR22579.1 - 0.18 11.6 0.8 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_7 PF15269.1 CAR22579.1 - 0.6 10.0 0.1 0.6 10.0 0.0 2.3 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_jaz PF12171.3 CAR22579.1 - 2 8.6 8.3 9.1 6.5 0.1 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CAR22579.1 - 2.6 8.4 12.5 4.1 7.8 2.6 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 CAR22579.1 - 4.8 7.0 5.9 11 5.9 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger Acetyltransf_1 PF00583.19 CAR22580.1 - 9.8e-08 31.9 0.0 3.6e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR22580.1 - 0.021 14.9 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.1 CAR22581.1 - 0.00056 20.0 16.1 0.017 15.4 2.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR22581.1 - 0.0007 19.7 17.3 0.038 14.3 3.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 CAR22581.1 - 0.026 14.6 0.8 0.026 14.6 0.5 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CAR22581.1 - 0.32 11.1 10.4 0.52 10.4 2.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 CAR22581.1 - 0.53 10.6 14.0 0.88 9.9 2.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Dicty_REP PF05086.7 CAR22581.1 - 3.6 5.2 9.6 4.9 4.7 6.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SAGA-Tad1 PF12767.2 CAR22581.1 - 5.3 6.6 13.6 0.83 9.2 6.6 1.6 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Cg6151-P PF10233.4 CAR22582.1 - 7.6e-41 138.6 12.1 9.6e-41 138.3 8.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4577 PF15145.1 CAR22582.1 - 0.3 11.0 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) DUF962 PF06127.6 CAR22582.1 - 3.3 7.6 6.2 11 5.9 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) COPI_assoc PF08507.5 CAR22582.1 - 7.9 6.1 16.0 11 5.7 8.1 2.4 1 1 1 2 2 2 0 COPI associated protein zinc_ribbon_6 PF14599.1 CAR22583.1 - 8.6e-25 86.3 4.6 8.6e-25 86.3 3.2 3.9 4 1 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 CAR22583.1 - 1.7e-12 47.3 23.3 1.7e-12 47.3 16.1 4.6 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 CAR22583.1 - 5.7e-08 32.4 8.1 5.7e-08 32.4 5.6 5.0 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 CAR22583.1 - 0.0002 20.9 2.9 0.0002 20.9 2.0 6.1 5 3 1 6 6 6 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR22583.1 - 0.00032 20.6 7.0 0.00032 20.6 4.9 5.3 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) HMG_box PF00505.14 CAR22584.1 - 3.9e-35 119.9 12.3 8.9e-20 70.7 4.3 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR22584.1 - 7.3e-19 67.9 17.1 1.1e-11 44.9 3.3 3.0 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.7 CAR22584.1 - 3.8e-08 32.8 0.0 0.0051 16.4 0.0 2.6 2 0 0 2 2 2 2 CHDNT (NUC034) domain EIIBC-GUT_N PF03612.9 CAR22584.1 - 0.061 12.9 2.0 0.12 11.9 1.2 1.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus dsDNA_bind PF01984.15 CAR22584.1 - 0.082 12.9 12.1 0.21 11.6 8.4 1.7 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Cyt-b5 PF00173.23 CAR22585.1 - 1.7e-20 72.5 0.0 3e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fusion_gly PF00523.13 CAR22585.1 - 0.11 10.5 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Cu_amine_oxid PF01179.15 CAR22587.1 - 1.5e-152 508.1 1.7 1.8e-152 507.8 1.2 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 CAR22587.1 - 0.0025 17.8 0.0 0.0081 16.2 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain dsDNA_bind PF01984.15 CAR22588.1 - 2.3e-25 88.6 1.9 2.8e-25 88.3 1.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.4 CAR22588.1 - 0.14 12.2 0.2 0.14 12.2 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region BTAD PF03704.12 CAR22588.1 - 0.16 12.2 6.6 0.15 12.4 4.0 1.4 1 1 0 1 1 1 0 Bacterial transcriptional activator domain PHD PF00628.24 CAR22589.1 - 2.2e-13 49.6 23.4 3.4e-10 39.4 7.8 2.8 2 1 1 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 CAR22589.1 - 0.37 10.0 7.2 0.78 9.0 0.3 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CAR22589.1 - 0.81 9.4 19.0 0.84 9.4 0.7 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 CAR22589.1 - 1.6 8.1 14.6 3.1 7.1 2.3 3.5 3 0 0 3 3 3 0 PHD-finger HEAT PF02985.17 CAR22590.1 - 1.6e-06 27.6 0.4 12 6.3 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 CAR22590.1 - 9.9e-05 22.5 1.4 1 9.6 0.0 5.5 5 1 1 6 6 6 1 HEAT repeats HEAT_EZ PF13513.1 CAR22590.1 - 0.0036 17.7 1.8 28 5.3 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat Form_Nir_trans PF01226.12 CAR22591.1 - 6.9e-63 211.8 26.1 8.5e-63 211.5 18.1 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Vac14_Fab1_bd PF12755.2 CAR22592.1 - 0.011 16.0 0.4 0.29 11.5 0.0 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region AA_permease PF00324.16 CAR22593.1 - 9e-110 367.2 47.0 1e-109 367.0 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR22593.1 - 1.9e-31 109.0 54.4 2.4e-31 108.7 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease zf-UBP PF02148.14 CAR22594.1 - 4.5e-21 74.7 4.1 1.1e-20 73.5 2.8 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 CAR22594.1 - 1e-18 66.8 0.0 2.7e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 CAR22594.1 - 3e-09 36.5 10.4 3e-09 36.5 7.2 2.0 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR22594.1 - 1.2e-05 24.8 8.5 1.2e-05 24.8 5.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR22594.1 - 2.3e-05 24.3 9.7 2.3e-05 24.3 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR22594.1 - 3e-05 23.5 6.1 3e-05 23.5 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR22594.1 - 0.00013 21.5 9.4 0.00013 21.5 6.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAR22594.1 - 0.00048 20.1 5.3 0.00048 20.1 3.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CAR22594.1 - 0.0041 16.7 3.2 0.0041 16.7 2.2 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CAR22594.1 - 0.015 15.0 3.9 0.047 13.5 2.7 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CAR22594.1 - 0.021 14.6 5.7 0.09 12.6 3.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CAR22594.1 - 0.024 14.2 7.7 0.057 13.0 5.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EB1 PF03271.12 CAR22594.1 - 0.27 11.2 3.4 0.95 9.5 2.4 2.0 1 1 0 1 1 1 0 EB1-like C-terminal motif Baculo_RING PF05883.6 CAR22594.1 - 1.3 8.8 5.5 0.27 11.0 1.1 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Pribosyl_synth PF14572.1 CAR22595.1 - 1e-40 139.4 3.5 3.3e-35 121.4 1.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CAR22595.1 - 8e-37 125.5 0.1 2.2e-36 124.0 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CAR22595.1 - 8.5e-11 41.6 0.8 3e-10 39.8 0.6 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAR22595.1 - 0.044 12.9 0.1 0.072 12.2 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HAD_2 PF13419.1 CAR22596.1 - 1.7e-19 70.7 0.0 2.1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR22596.1 - 4.9e-08 33.6 0.0 5.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CAR22596.1 - 0.027 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.1 CAR22597.1 - 5.6e-11 42.0 4.9 1.1e-10 41.1 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR22597.1 - 2.8e-09 36.9 2.2 6e-09 35.8 1.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAR22597.1 - 8.8e-08 31.7 3.3 1.5e-07 31.0 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CAR22597.1 - 1.9e-06 27.4 3.3 3.9e-06 26.4 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR22597.1 - 4.9e-05 22.8 5.8 9.4e-05 21.9 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR22597.1 - 0.00022 21.2 6.4 0.001 19.0 4.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAR22597.1 - 0.00065 19.4 1.3 0.0015 18.3 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CAR22597.1 - 0.042 13.5 1.8 0.12 12.0 1.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 CAR22597.1 - 0.05 13.5 5.1 0.19 11.6 3.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 CAR22597.1 - 0.099 12.4 0.7 0.17 11.6 0.2 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 CAR22597.1 - 1.3 8.5 5.1 0.5 9.8 1.4 1.8 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.2 CAR22597.1 - 1.9 8.6 5.2 4.8 7.2 3.6 1.7 1 1 0 1 1 1 0 RING-variant domain UDPGP PF01704.13 CAR22598.1 - 1.9e-191 636.1 0.0 2.3e-191 635.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Zn_clus PF00172.13 CAR22599.1 - 1.4e-09 37.6 10.2 2.6e-09 36.8 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTU PF02338.14 CAR22600.1 - 1.6e-18 67.4 0.4 6.5e-18 65.4 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CAR22600.1 - 6.2e-05 22.4 3.0 0.0022 17.3 0.0 3.0 3 0 0 3 3 3 1 Peptidase C65 Otubain YchF-GTPase_C PF06071.8 CAR22601.1 - 2e-29 101.2 0.0 3.6e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CAR22601.1 - 2e-14 53.5 0.1 4.3e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR22601.1 - 0.00028 20.2 0.0 0.00047 19.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 CAR22601.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain AAA_14 PF13173.1 CAR22601.1 - 0.12 12.3 0.0 0.4 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_S10 PF00338.17 CAR22602.1 - 1.6e-27 95.1 1.1 1.9e-27 94.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Retrotrans_gag PF03732.12 CAR22602.1 - 0.091 12.8 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Retrotransposon gag protein Cnl2_NKP2 PF09447.5 CAR22602.1 - 0.76 9.5 4.0 0.2 11.3 0.6 1.6 2 0 0 2 2 2 0 Cnl2/NKP2 family protein DUF1688 PF07958.6 CAR22603.1 - 1.4e-157 524.5 0.0 1.6e-157 524.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF3616 PF12275.3 CAR22603.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) SSF PF00474.12 CAR22604.1 - 6.5e-18 64.5 31.8 9e-18 64.1 22.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Lung_7-TM_R PF06814.8 CAR22605.1 - 1.7e-83 280.0 22.2 2e-83 279.7 15.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SieB PF14163.1 CAR22605.1 - 1.4 8.5 6.0 4.1 6.9 0.4 3.0 1 1 1 2 2 2 0 Superinfection exclusion protein B Nfu_N PF08712.6 CAR22606.1 - 2e-26 91.4 0.0 4.8e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CAR22606.1 - 2.3e-22 78.5 0.1 3.8e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 CAR22606.1 - 0.0059 16.4 1.1 0.011 15.5 0.8 1.5 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Pterin_4a PF01329.14 CAR22607.1 - 6.9e-27 93.0 0.1 7.9e-27 92.8 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Adap_comp_sub PF00928.16 CAR22608.1 - 1.6e-58 197.8 0.3 2.2e-58 197.4 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CAR22608.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRF_GI PF12614.3 CAR22609.1 - 0.024 14.4 0.3 0.064 13.0 0.2 1.7 1 0 0 1 1 1 0 Ribosome recycling factor Tox-PLDMTX PF15645.1 CAR22609.1 - 0.078 13.0 0.6 0.49 10.4 0.2 2.2 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold Opi1 PF08618.5 CAR22610.1 - 2.9e-39 135.2 11.3 7.4e-24 84.4 0.1 3.0 1 1 2 3 3 3 3 Transcription factor Opi1 PBP1_TM PF14812.1 CAR22610.1 - 0.21 11.8 13.0 5.9 7.2 6.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.8 CAR22610.1 - 0.36 10.3 9.8 0.07 12.6 3.4 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Snf7 PF03357.16 CAR22611.1 - 3.6e-28 98.0 16.6 3.6e-28 98.0 11.5 1.6 2 0 0 2 2 2 1 Snf7 PAS_7 PF12860.2 CAR22611.1 - 0.00047 20.1 2.7 0.1 12.5 0.0 2.7 3 0 0 3 3 3 2 PAS fold Rota_NSP4 PF01452.11 CAR22611.1 - 0.063 12.6 0.1 0.063 12.6 0.1 2.4 1 1 1 2 2 2 0 Rotavirus non structural protein DUF4473 PF14747.1 CAR22611.1 - 1.9 8.7 8.0 0.45 10.7 0.8 2.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4473) CLU PF13236.1 CAR22612.1 - 2.2e-75 252.8 0.3 4.7e-75 251.7 0.2 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 CAR22612.1 - 1e-35 123.1 0.5 4.7e-22 78.7 0.0 3.5 3 0 0 3 3 3 2 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 CAR22612.1 - 3.5e-13 49.4 0.1 1.6e-12 47.3 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 CAR22612.1 - 6e-12 45.3 0.8 3e-06 27.0 0.0 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 CAR22612.1 - 6.2e-06 25.9 0.1 0.00076 19.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR22612.1 - 0.00026 20.6 0.6 0.35 10.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR22612.1 - 0.00036 20.0 0.5 0.66 9.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR22612.1 - 0.0013 18.2 0.6 0.66 9.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAR22612.1 - 0.11 12.0 0.4 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 TPR repeat CTP_transf_1 PF01148.15 CAR22613.1 - 6.3e-08 32.5 0.7 6.3e-08 32.5 0.5 4.3 2 2 1 3 3 3 2 Cytidylyltransferase family DUF3353 PF11833.3 CAR22613.1 - 7.3 5.9 10.5 15 5.0 1.9 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3353) BUD22 PF09073.5 CAR22614.1 - 3.4e-84 283.4 40.3 3.4e-84 283.4 27.9 1.3 1 1 0 1 1 1 1 BUD22 p450 PF00067.17 CAR22615.1 - 3.2e-55 187.4 0.1 4e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Spc42p PF11544.3 CAR22616.1 - 5e-25 87.2 3.1 5e-25 87.2 2.2 1.9 2 0 0 2 2 2 1 Spindle pole body component Spc42p DivIVA PF05103.8 CAR22616.1 - 0.0026 17.7 1.1 0.065 13.2 0.4 2.2 2 0 0 2 2 2 1 DivIVA protein DUF3338 PF11819.3 CAR22616.1 - 0.037 13.4 3.1 3.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) tRNA_U5-meth_tr PF05958.6 CAR22616.1 - 0.095 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase KilA-N PF04383.8 CAR22617.1 - 8.2e-05 22.2 0.0 0.00067 19.2 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Fungal_trans PF04082.13 CAR22618.1 - 6.7e-21 74.3 0.7 1.1e-20 73.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR22618.1 - 7.7e-08 32.1 10.6 7.7e-08 32.1 7.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_primase_lrg PF04104.9 CAR22619.1 - 1.5e-86 289.9 0.2 2.7e-86 289.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Amino_oxidase PF01593.19 CAR22620.1 - 2.6e-63 214.6 0.0 9.2e-63 212.8 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CAR22620.1 - 2.2e-14 53.2 0.3 4.7e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CAR22620.1 - 9.8e-11 42.0 0.0 4.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CAR22620.1 - 8.5e-09 34.7 0.0 4.3e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CAR22620.1 - 5.5e-06 25.6 0.1 0.0006 18.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 CAR22620.1 - 7.1e-06 25.1 0.2 1.4e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CAR22620.1 - 1.6e-05 24.0 0.1 0.025 13.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 CAR22620.1 - 2.3e-05 23.0 0.6 0.0059 15.1 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 CAR22620.1 - 0.00017 21.9 0.7 0.0016 18.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR22620.1 - 0.00026 20.9 0.2 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAR22620.1 - 0.00066 18.8 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CAR22620.1 - 0.0013 17.7 0.6 0.0052 15.6 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CAR22620.1 - 0.0064 16.2 0.4 2.8 7.6 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.2 CAR22620.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Copper-fist PF00649.13 CAR22621.1 - 6.3e-22 76.4 3.6 1.8e-21 75.0 2.5 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Thyroglobulin_1 PF00086.13 CAR22621.1 - 0.0023 17.2 0.5 0.0056 16.0 0.3 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat UQ_con PF00179.21 CAR22622.1 - 1.2e-48 164.0 0.0 1.4e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR22622.1 - 0.011 15.4 0.1 0.045 13.5 0.0 2.0 1 1 0 2 2 2 0 Prokaryotic E2 family B RWD PF05773.17 CAR22622.1 - 0.085 12.7 1.1 0.14 12.0 0.8 1.9 1 1 0 1 1 1 0 RWD domain Glyco_hydro_76 PF03663.9 CAR22623.1 - 2.3e-152 507.6 24.4 2.8e-152 507.4 16.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF2347 PF09804.4 CAR22624.1 - 1.5e-75 254.1 0.1 2e-75 253.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 CAR22624.1 - 8.2e-19 68.3 4.1 2.5e-10 40.7 1.5 3.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.4 CAR22624.1 - 4.9e-09 35.1 0.7 8.6e-06 24.4 0.1 2.1 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 CAR22624.1 - 5.2e-05 22.9 0.0 0.00017 21.2 0.0 1.9 2 0 0 2 2 2 1 Stabilization of polarity axis BLOC1_2 PF10046.4 CAR22625.1 - 0.00074 19.6 2.8 0.0018 18.3 2.0 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tektin PF03148.9 CAR22625.1 - 0.001 17.6 1.2 0.44 9.0 0.5 2.0 2 0 0 2 2 2 2 Tektin family DUF2090 PF09863.4 CAR22625.1 - 0.038 12.8 0.1 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Seryl_tRNA_N PF02403.17 CAR22625.1 - 0.041 13.8 1.5 0.052 13.5 1.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 CAR22625.1 - 0.045 13.1 3.0 0.063 12.7 2.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3347 PF11827.3 CAR22625.1 - 0.094 12.7 0.4 0.1 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Rabaptin PF03528.10 CAR22625.1 - 0.11 12.4 2.2 0.14 12.0 1.6 1.3 1 1 0 1 1 1 0 Rabaptin Fib_alpha PF08702.5 CAR22625.1 - 0.12 12.4 0.3 5.3 7.1 0.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HLH PF00010.21 CAR22625.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.7 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain Cep57_MT_bd PF06657.8 CAR22625.1 - 0.41 10.6 3.3 0.3 11.0 0.9 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Med21 PF11221.3 CAR22625.1 - 0.53 10.2 2.8 0.66 9.9 0.9 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex TrmE_N PF10396.4 CAR22626.1 - 3.9e-35 120.2 0.0 1e-34 118.9 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 CAR22626.1 - 7.8e-23 80.6 0.2 2.3e-22 79.1 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 CAR22626.1 - 5.4e-15 55.5 0.0 1.6e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 CAR22626.1 - 5.1e-13 48.5 0.4 7.9e-13 47.9 0.3 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR22626.1 - 2.5e-07 30.6 0.9 0.0022 17.8 0.0 2.7 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 CAR22626.1 - 3.8e-07 29.7 0.4 8.7e-05 22.0 0.1 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.17 CAR22626.1 - 6.4e-05 22.3 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR22626.1 - 0.00014 22.3 0.0 0.00043 20.7 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR22626.1 - 0.00016 20.9 0.1 0.0017 17.6 0.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family cobW PF02492.14 CAR22626.1 - 0.0006 19.3 1.3 0.026 13.9 0.2 2.3 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CAR22626.1 - 0.0056 16.9 0.3 0.021 15.1 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AIG1 PF04548.11 CAR22626.1 - 0.0063 15.6 0.3 0.011 14.8 0.2 1.4 1 0 0 1 1 1 1 AIG1 family SRP54 PF00448.17 CAR22626.1 - 0.0064 15.9 0.2 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DUF258 PF03193.11 CAR22626.1 - 0.011 14.9 0.1 0.06 12.5 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CAR22626.1 - 0.013 14.9 0.1 1.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 CAR22626.1 - 0.047 12.8 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Ribonuclease_3 PF00636.21 CAR22628.1 - 2.3e-08 34.4 0.0 4.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 CAR22628.1 - 1.8e-06 28.4 0.0 3.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif PAC2 PF09754.4 CAR22629.1 - 0.044 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 PAC2 family Pex2_Pex12 PF04757.9 CAR22630.1 - 1.2e-37 129.5 12.3 1.5e-37 129.2 8.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CAR22630.1 - 2.1e-07 30.8 1.9 3.8e-07 30.0 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR22630.1 - 0.00055 19.7 0.9 0.001 18.8 0.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAR22630.1 - 0.00072 19.1 0.2 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR22630.1 - 0.0011 18.7 3.4 0.0019 18.0 2.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CAR22630.1 - 0.0037 16.8 0.5 0.0065 16.1 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ABA_GPCR PF12430.3 CAR22630.1 - 0.053 12.6 1.5 0.085 11.9 0.1 2.0 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor zf-RING_6 PF14835.1 CAR22630.1 - 0.16 11.7 0.7 0.31 10.8 0.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein F_bP_aldolase PF01116.15 CAR22631.1 - 3.3e-95 318.4 0.0 3.7e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C26 PF07722.8 CAR22631.1 - 0.13 11.6 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 TPP_enzyme_M PF00205.17 CAR22632.1 - 3.1e-35 120.9 0.0 5e-34 116.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CAR22632.1 - 5.5e-33 113.8 0.1 9.4e-33 113.1 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAR22632.1 - 3.7e-12 46.0 0.1 9.7e-12 44.7 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.1 CAR22632.1 - 0.11 12.3 0.1 22 5.0 0.0 2.7 2 0 0 2 2 2 0 OCC1 family DUF89 PF01937.14 CAR22633.1 - 4.8e-113 377.5 0.8 5.5e-113 377.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DWNN PF08783.6 CAR22634.1 - 3.4e-30 103.8 0.2 1.2e-29 102.0 0.0 1.9 2 0 0 2 2 2 1 DWNN domain zf-Nse PF11789.3 CAR22634.1 - 8.9e-07 28.3 0.8 2.2e-06 27.0 0.2 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CAR22634.1 - 0.00032 20.5 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-CCHC_2 PF13696.1 CAR22634.1 - 0.00086 18.7 4.1 0.0016 17.9 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CAR22634.1 - 0.0029 17.4 4.1 0.0029 17.4 2.8 2.0 2 0 0 2 2 2 1 Zinc knuckle Zn_Tnp_IS1595 PF12760.2 CAR22634.1 - 0.0079 15.9 0.4 0.51 10.1 0.0 2.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Rubredoxin PF00301.15 CAR22634.1 - 0.0081 16.0 1.0 1.7 8.5 0.0 3.2 3 0 0 3 3 3 1 Rubredoxin zf-CCHC_3 PF13917.1 CAR22634.1 - 0.012 15.3 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-DNL PF05180.7 CAR22634.1 - 0.028 14.1 0.2 0.077 12.7 0.1 1.7 1 0 0 1 1 1 0 DNL zinc finger CpXC PF14353.1 CAR22634.1 - 0.093 12.6 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 CpXC protein TFIIA_gamma_C PF02751.9 CAR22635.1 - 7.7e-27 92.8 3.4 1.2e-26 92.2 2.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 CAR22635.1 - 2.3e-24 84.6 0.2 3.2e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TAP42 PF04177.7 CAR22636.1 - 3.8e-86 289.1 18.3 4.3e-86 288.9 12.7 1.0 1 0 0 1 1 1 1 TAP42-like family Nup160 PF11715.3 CAR22637.1 - 2.6e-13 48.9 0.5 1.2e-12 46.7 0.3 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Striatin PF08232.7 CAR22638.1 - 1.6e-24 86.7 17.8 2.4e-23 82.9 1.8 4.2 3 1 1 4 4 4 2 Striatin family Mto2_bdg PF12808.2 CAR22638.1 - 0.0037 17.3 1.9 0.0037 17.3 1.3 2.1 2 0 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Herpes_BLRF2 PF05812.7 CAR22638.1 - 0.023 14.5 0.7 0.023 14.5 0.5 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF1192 PF06698.6 CAR22638.1 - 0.097 12.4 0.8 0.24 11.2 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) BAF1_ABF1 PF04684.8 CAR22638.1 - 3.9 6.1 13.9 0.19 10.5 6.0 1.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TCTP PF00838.12 CAR22639.1 - 1.9e-71 239.3 1.2 2.2e-71 239.2 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.5 CAR22639.1 - 0.071 11.9 0.0 0.08 11.7 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family adh_short PF00106.20 CAR22640.1 - 4.6e-18 65.6 0.1 9e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CAR22640.1 - 6.4e-11 42.4 0.1 1.8e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR22640.1 - 1.2e-05 25.0 0.9 0.025 14.2 0.0 2.8 2 1 1 3 3 3 2 KR domain NAD_binding_10 PF13460.1 CAR22640.1 - 0.023 14.7 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 CAR22640.1 - 0.04 13.3 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CUE PF02845.11 CAR22641.1 - 0.00012 21.4 1.0 0.0002 20.7 0.1 1.9 2 0 0 2 2 2 1 CUE domain ATP-grasp_4 PF13535.1 CAR22641.1 - 9.7 5.8 8.5 1.1 8.9 2.1 2.3 2 0 0 2 2 2 0 ATP-grasp domain UPF0203 PF05254.7 CAR22642.1 - 4.9e-30 103.1 3.1 5.8e-30 102.9 2.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 CAR22642.1 - 0.0019 17.9 3.6 0.022 14.5 1.0 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Baculo_p74_N PF08404.5 CAR22642.1 - 0.022 13.5 0.6 0.024 13.4 0.4 1.1 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal UCR_hinge PF02320.11 CAR22642.1 - 0.046 13.6 4.2 0.43 10.5 2.9 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Mvb12 PF09452.5 CAR22642.1 - 0.49 10.6 2.1 0.37 10.9 0.4 1.6 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 COX6B PF02297.12 CAR22642.1 - 0.83 9.7 7.9 1.4 8.9 0.8 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DASH_Ask1 PF08655.5 CAR22643.1 - 1.2e-27 95.5 0.2 1.9e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 NLPC_P60 PF00877.14 CAR22643.1 - 0.11 12.2 0.1 9.5 6.1 0.0 2.3 2 0 0 2 2 2 0 NlpC/P60 family Pox_C4_C10 PF03336.8 CAR22643.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Frag1 PF10277.4 CAR22644.1 - 8.6e-80 267.2 19.9 1e-79 267.0 13.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF962 PF06127.6 CAR22644.1 - 0.09 12.6 5.3 0.61 10.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF3812 PF12757.2 CAR22645.1 - 4.3e-33 113.9 1.6 4.3e-33 113.9 1.1 5.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3812) FCH PF00611.18 CAR22646.1 - 7.4e-20 70.9 0.5 7.4e-20 70.9 0.3 3.1 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CAR22646.1 - 0.00028 20.4 0.1 0.00054 19.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR22646.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Phage_CP76 PF06892.6 CAR22646.1 - 0.029 13.6 0.4 0.26 10.6 0.0 2.4 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) SH3_1 PF00018.23 CAR22646.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Histone PF00125.19 CAR22647.1 - 8.7e-27 93.0 0.6 2.6e-26 91.5 0.4 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAR22647.1 - 0.0018 18.4 0.1 0.0034 17.5 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Actin PF00022.14 CAR22648.1 - 1e-20 73.5 0.4 2.2e-18 65.8 0.3 2.8 1 1 0 1 1 1 1 Actin DUF4137 PF13593.1 CAR22649.1 - 2e-125 418.0 20.6 2.3e-125 417.8 14.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Peptidase_S24 PF00717.18 CAR22650.1 - 2.1e-06 27.2 1.5 1.3e-05 24.7 1.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CAR22650.1 - 1.1e-05 25.0 0.1 0.0058 16.1 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Rhodanese PF00581.15 CAR22651.1 - 5.1e-11 42.9 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 CAR22652.1 - 1e-42 146.0 0.0 2e-42 145.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22652.1 - 1.7e-18 66.6 0.0 5.6e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR22652.1 - 8.1e-05 21.7 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR22652.1 - 0.01 15.6 0.0 0.052 13.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Herpes_UL87 PF03043.9 CAR22652.1 - 0.14 10.4 0.0 0.3 9.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL87 family zf-C2H2 PF00096.21 CAR22653.1 - 1.6e-11 43.8 16.4 6.4e-06 26.2 2.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR22653.1 - 2e-09 37.1 15.0 7.8e-05 22.7 2.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR22653.1 - 1.1e-07 31.7 21.9 1.9e-06 27.8 3.7 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CAR22653.1 - 7.3e-05 22.7 13.9 0.008 16.2 4.7 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CAR22653.1 - 0.00019 21.1 8.1 0.055 13.2 1.9 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 CAR22653.1 - 0.0095 15.8 3.3 0.0095 15.8 2.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 CAR22653.1 - 0.19 11.8 5.9 0.46 10.6 4.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CAR22653.1 - 0.2 11.8 9.9 1 9.6 2.8 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.10 CAR22653.1 - 0.37 10.2 3.1 2.6 7.5 2.0 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.6 CAR22653.1 - 2.3 7.8 8.2 5.2 6.7 0.7 3.4 2 1 1 3 3 3 0 GAGA factor zf-H2C2_5 PF13909.1 CAR22653.1 - 3.8 7.9 15.0 13 6.2 2.9 3.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF629 PF04780.7 CAR22653.1 - 4.7 5.6 8.6 1 7.7 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) HMA PF00403.21 CAR22655.1 - 2.6e-06 27.4 0.0 4.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 CAR22655.1 - 1.4e-05 25.2 0.0 3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CorA PF01544.13 CAR22656.1 - 7.1e-40 136.8 4.6 6.2e-22 77.9 0.2 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein PC4 PF02229.11 CAR22657.1 - 1.3e-20 72.3 0.0 2e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Aldo_ket_red PF00248.16 CAR22658.1 - 7.8e-47 159.4 0.0 9.6e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SHOCT PF09851.4 CAR22658.1 - 0.098 12.1 0.3 0.34 10.4 0.2 2.0 1 0 0 1 1 1 0 Short C-terminal domain Bap31 PF05529.7 CAR22659.1 - 6.8e-49 165.9 0.0 7.9e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like IncA PF04156.9 CAR22659.1 - 0.00041 20.0 0.5 0.00059 19.4 0.4 1.3 1 0 0 1 1 1 1 IncA protein Mis12 PF05859.7 CAR22659.1 - 0.0062 16.3 0.1 0.0094 15.7 0.1 1.3 1 0 0 1 1 1 1 Mis12 protein DUF4446 PF14584.1 CAR22659.1 - 0.053 13.3 1.7 0.37 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.14 CAR22659.1 - 0.19 9.5 1.0 0.3 8.9 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 CAR22659.1 - 0.2 11.1 4.7 1 8.9 3.1 1.9 1 1 0 1 1 1 0 Septum formation initiator ING PF12998.2 CAR22660.1 - 7.7e-22 77.5 0.0 1.7e-21 76.4 0.0 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CAR22660.1 - 1e-08 34.6 6.8 1.7e-08 34.0 4.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CAR22660.1 - 0.019 15.1 0.2 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 CAR22660.1 - 0.039 13.2 1.9 0.075 12.3 1.3 1.5 1 0 0 1 1 1 0 PHD-finger Med3 PF11593.3 CAR22660.1 - 0.87 8.7 8.0 1 8.5 5.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ras PF00071.17 CAR22661.1 - 4.1e-56 188.8 0.1 5.1e-56 188.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR22661.1 - 1.1e-20 74.2 0.1 2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR22661.1 - 1e-08 34.6 0.0 1.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR22661.1 - 4.1e-06 26.3 0.1 2.3e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR22661.1 - 0.00019 21.3 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR22661.1 - 0.076 12.1 0.2 0.18 11.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR22661.1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain DAD PF02109.11 CAR22662.1 - 1.3e-37 128.2 5.3 1.6e-37 128.0 3.7 1.0 1 0 0 1 1 1 1 DAD family DUF2371 PF10177.4 CAR22662.1 - 0.053 13.4 0.1 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF3353 PF11833.3 CAR22662.1 - 4.7 6.6 5.4 6.2 6.2 3.4 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) Y_phosphatase2 PF03162.8 CAR22663.1 - 4.7e-56 188.6 0.0 5.5e-56 188.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAR22663.1 - 2.9e-05 24.3 0.0 0.00017 21.9 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family ApoO PF09769.4 CAR22665.1 - 4.8e-09 36.1 0.1 1.7e-05 24.6 0.0 2.9 3 0 0 3 3 3 2 Apolipoprotein O Activator-TraM PF11657.3 CAR22665.1 - 0.12 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM Aa_trans PF01490.13 CAR22666.1 - 1.7e-93 313.3 37.6 2e-93 313.0 26.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DNA_pol_B PF00136.16 CAR22667.1 - 6.5e-117 391.1 2.3 1.1e-116 390.4 1.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CAR22667.1 - 2.3e-67 226.0 2.2 4.5e-67 225.0 1.5 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CAR22667.1 - 2.1e-43 148.4 0.0 4.1e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CAR22667.1 - 2.3e-21 75.3 8.9 6.4e-21 73.9 6.2 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal GRA6 PF05084.8 CAR22667.1 - 0.0026 17.3 0.8 0.0056 16.2 0.5 1.5 1 0 0 1 1 1 1 Granule antigen protein (GRA6) zinc_ribbon_4 PF13717.1 CAR22667.1 - 0.093 12.4 1.9 2.5 7.8 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAR22667.1 - 0.1 12.2 2.1 3.1 7.4 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain SNARE PF05739.14 CAR22668.1 - 3e-16 58.8 2.3 7.4e-16 57.5 1.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.1 CAR22668.1 - 2.2e-08 34.0 9.8 3.4e-08 33.4 0.5 3.5 2 2 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.16 CAR22668.1 - 0.00013 21.5 0.3 0.00029 20.3 0.2 1.6 1 0 0 1 1 1 1 Synaptobrevin Herpes_US9 PF06072.6 CAR22668.1 - 0.011 15.5 0.5 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 PET PF06297.9 CAR22668.1 - 0.063 12.9 0.3 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 PET Domain T2SF PF00482.18 CAR22668.1 - 0.17 11.7 1.4 4.8 7.1 0.2 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F MMPL PF03176.10 CAR22668.1 - 0.19 10.4 2.4 0.31 9.7 1.6 1.4 1 1 0 1 1 1 0 MMPL family DUF912 PF06024.7 CAR22668.1 - 0.25 11.3 2.8 0.18 11.8 0.3 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OppC_N PF12911.2 CAR22668.1 - 0.28 10.6 4.9 0.5 9.7 3.4 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1510 PF07423.6 CAR22668.1 - 5.3 6.3 8.4 0.67 9.2 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) bZIP_2 PF07716.10 CAR22669.1 - 9 6.2 12.4 0.036 13.8 1.0 2.6 2 1 0 2 2 2 0 Basic region leucine zipper RGS PF00615.14 CAR22670.1 - 1.8e-12 47.3 0.0 3.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain HMGL-like PF00682.14 CAR22671.1 - 4.8e-76 255.5 0.0 7.5e-76 254.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CAR22671.1 - 6.9e-26 90.6 0.3 1.4e-25 89.6 0.2 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.13 CAR22672.1 - 5.2e-93 311.2 0.2 9.1e-93 310.4 0.1 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CAR22672.1 - 1.7e-25 90.3 0.1 2.7e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 CAR22673.1 - 4.5e-35 119.2 0.5 7.2e-35 118.5 0.3 1.3 1 0 0 1 1 1 1 YEATS family His_Phos_1 PF00300.17 CAR22674.1 - 4.9e-19 68.9 0.0 1.1e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 CAR22674.1 - 6.9e-14 51.0 0.0 1.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit Maf PF02545.9 CAR22675.1 - 4.6e-44 149.8 0.0 5.9e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RRM_1 PF00076.17 CAR22676.1 - 3.7e-18 64.9 0.0 6.6e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR22676.1 - 5.8e-14 51.8 0.1 1.5e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR22676.1 - 8.5e-10 38.3 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ebola_NP PF05505.7 CAR22676.1 - 0.34 8.9 3.0 0.086 10.8 0.1 1.4 2 0 0 2 2 2 0 Ebola nucleoprotein Cyt-b5 PF00173.23 CAR22677.1 - 1.1e-26 92.4 0.1 1.4e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CLASP_N PF12348.3 CAR22678.1 - 0.03 13.6 0.0 0.99 8.7 0.0 2.7 2 1 1 3 3 3 0 CLASP N terminal Cnd1 PF12717.2 CAR22678.1 - 0.034 13.9 0.0 10 5.8 0.0 2.4 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DEAD PF00270.24 CAR22679.1 - 9.6e-45 152.1 0.0 1.9e-43 147.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR22679.1 - 4.9e-29 100.0 0.0 1.1e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR22679.1 - 0.0017 18.2 0.0 0.0046 16.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CAR22679.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1253 PF06862.7 CAR22679.1 - 0.03 12.7 0.0 0.27 9.6 0.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1253) RNA_pol_L_2 PF13656.1 CAR22680.1 - 7.3e-32 108.6 0.1 3e-31 106.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CAR22680.1 - 1.2e-12 46.7 0.0 1.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Adeno_E1B_55K_N PF04623.7 CAR22680.1 - 0.18 12.3 1.2 0.35 11.3 0.8 1.6 1 1 0 1 1 1 0 Adenovirus E1B protein N-terminus Arginase PF00491.16 CAR22681.1 - 1e-73 248.0 0.0 1.2e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family PEX11 PF05648.9 CAR22682.1 - 3.1e-08 33.1 5.5 8.3e-07 28.4 0.2 3.4 3 1 0 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) DASH_Dad3 PF08656.5 CAR22682.1 - 0.023 14.3 1.3 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4102 PF13356.1 CAR22682.1 - 0.07 13.0 0.1 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4102) 2-Hacid_dh_C PF02826.14 CAR22683.1 - 1e-35 122.5 0.0 1.4e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR22683.1 - 0.00025 20.5 0.0 0.00031 20.2 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Semialdhyde_dh PF01118.19 CAR22683.1 - 0.0013 18.9 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CAR22683.1 - 0.039 13.8 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TFIIA PF03153.8 CAR22684.1 - 1.2e-57 196.5 21.5 2.3e-33 116.6 7.8 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit ChlamPMP_M PF07548.6 CAR22684.1 - 0.13 11.9 3.7 0.21 11.3 2.6 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Kinetocho_Slk19 PF12709.2 CAR22685.1 - 6.5e-31 106.2 13.3 6.5e-31 106.2 9.2 9.4 2 1 7 10 10 10 1 Central kinetochore-associated Reo_sigmaC PF04582.7 CAR22685.1 - 0.066 12.3 28.9 0.16 11.1 7.6 4.2 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Complex1_49kDa PF00346.14 CAR22685.1 - 0.23 10.4 1.2 0.55 9.1 0.8 1.6 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF812 PF05667.6 CAR22685.1 - 2.6 6.4 74.5 0.062 11.7 10.6 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Filament PF00038.16 CAR22685.1 - 4.3 6.7 90.1 0.31 10.4 37.1 5.0 1 1 2 4 4 4 0 Intermediate filament protein RhoGAP PF00620.22 CAR22686.1 - 1.6e-32 112.1 0.0 4.6e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.19 CAR22686.1 - 3.7e-06 26.6 0.7 8e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 PX domain PH PF00169.24 CAR22686.1 - 5.3e-06 26.5 0.0 2.2e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 PH domain Radical_SAM PF04055.16 CAR22687.1 - 1.5e-14 54.5 0.0 2.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Ivy PF08816.6 CAR22687.1 - 0.1 12.5 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) Hist_deacetyl PF00850.14 CAR22689.1 - 2.5e-63 214.2 1.1 5.1e-63 213.2 0.2 1.8 2 0 0 2 2 2 1 Histone deacetylase domain Peptidase_C14 PF00656.17 CAR22690.1 - 2.7e-71 240.1 0.2 3.6e-71 239.7 0.1 1.1 1 0 0 1 1 1 1 Caspase domain DUF342 PF03961.8 CAR22691.1 - 0.00031 19.3 8.2 0.00031 19.3 5.7 3.8 2 1 1 3 3 3 1 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 CAR22691.1 - 0.04 13.7 20.7 0.9 9.3 1.0 4.9 2 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Col_cuticle_N PF01484.12 CAR22691.1 - 0.089 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Lectin_N PF03954.9 CAR22691.1 - 0.49 9.7 11.7 0.021 14.2 1.7 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain NUDIX PF00293.23 CAR22692.1 - 4.1e-29 100.9 0.0 6.6e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SpoU_methylase PF00588.14 CAR22693.1 - 1e-28 99.9 0.0 2.6e-28 98.7 0.0 1.6 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 CAR22693.1 - 2e-12 47.0 0.1 5.9e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding IGPD PF00475.13 CAR22694.1 - 4.3e-61 205.0 0.6 7.1e-61 204.3 0.4 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Mit_ribos_Mrp51 PF11709.3 CAR22695.1 - 1.4e-92 310.3 0.2 1.9e-92 309.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DEAD PF00270.24 CAR22696.1 - 8.9e-45 152.2 0.0 2.3e-43 147.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR22696.1 - 2.4e-27 94.5 0.1 5e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR22696.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 CAR22696.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 CAR22696.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Tfb2 PF03849.9 CAR22697.1 - 1.4e-154 514.2 2.7 1.4e-154 514.2 1.8 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CAR22697.1 - 8.2e-06 25.5 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNA_pol_Rpb2_6 PF00562.23 CAR22698.1 - 2.8e-118 395.0 0.1 2.8e-118 395.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CAR22698.1 - 5.8e-61 204.9 1.5 1.3e-60 203.8 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CAR22698.1 - 6.1e-43 146.4 3.8 1.6e-42 145.0 2.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CAR22698.1 - 1.5e-30 105.2 0.1 5.4e-30 103.4 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CAR22698.1 - 1.2e-26 92.2 1.0 3e-26 91.0 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CAR22698.1 - 5.6e-19 67.6 0.3 1.7e-18 66.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CAR22698.1 - 7.2e-12 45.0 0.1 2.2e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 CAR22698.1 - 0.00034 19.0 0.0 0.00074 17.9 0.0 1.5 1 0 0 1 1 1 1 Baculovirus Y142 protein Mei5 PF10376.4 CAR22699.1 - 3.1e-33 115.1 15.1 3.7e-33 114.9 10.4 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein DNA_primase_lrg PF04104.9 CAR22699.1 - 0.31 10.2 2.2 0.29 10.3 0.7 1.5 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit ParB PF08775.5 CAR22699.1 - 1 9.6 9.6 0.14 12.4 1.4 2.3 1 1 1 2 2 2 0 ParB family DDHD PF02862.12 CAR22699.1 - 3.1 7.5 6.4 5.2 6.8 4.4 1.5 1 1 0 1 1 1 0 DDHD domain Noc2 PF03715.8 CAR22700.1 - 6.9e-128 425.7 1.1 6.9e-128 425.7 0.8 2.6 2 1 0 2 2 2 1 Noc2p family MMR_HSR1 PF01926.18 CAR22701.1 - 9.5e-09 35.2 0.1 1.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CAR22701.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CAR22701.1 - 0.047 12.8 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAR22701.1 - 0.052 14.3 0.1 0.18 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 CAR22701.1 - 0.053 12.7 0.2 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.1 CAR22701.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 CAR22701.1 - 0.071 12.5 0.0 4 6.8 0.0 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CAR22701.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CAR22702.1 - 9.8e-112 373.0 3.3 1.2e-111 372.7 2.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Vps51 PF08700.6 CAR22702.1 - 0.43 10.4 6.8 2.8 7.8 0.4 2.7 2 0 0 2 2 2 0 Vps51/Vps67 V_ATPase_I PF01496.14 CAR22702.1 - 6 4.5 8.0 9.4 3.9 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribonuc_red_lgC PF02867.10 CAR22703.1 - 8.6e-208 691.2 0.0 1.2e-207 690.8 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CAR22703.1 - 2.9e-23 81.4 0.0 5.9e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain NRDD PF13597.1 CAR22703.1 - 0.062 11.3 0.0 0.095 10.7 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Ribonuclease_T2 PF00445.13 CAR22704.1 - 1.4e-39 135.6 0.9 2.1e-39 135.1 0.6 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Lzipper-MIP1 PF14389.1 CAR22705.1 - 0.024 14.7 0.3 4.6 7.4 0.0 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 SlyX PF04102.7 CAR22705.1 - 0.04 14.2 0.6 0.18 12.2 0.4 2.1 1 1 0 1 1 1 0 SlyX KLRAQ PF10205.4 CAR22705.1 - 1.1 9.3 3.7 0.71 9.9 0.4 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Y_phosphatase PF00102.22 CAR22706.1 - 5.5e-57 192.8 0.0 2.7e-56 190.5 0.0 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CAR22706.1 - 6.8e-05 23.1 0.0 0.00037 20.7 0.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CAR22706.1 - 0.00089 18.8 0.0 0.003 17.1 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TMEM61 PF15105.1 CAR22706.1 - 0.028 13.9 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 TMEM61 protein family PTPlike_phytase PF14566.1 CAR22706.1 - 0.035 14.1 0.5 1 9.3 0.0 3.0 3 0 0 3 3 3 0 Inositol hexakisphosphate IBN_N PF03810.14 CAR22707.1 - 4e-17 61.8 0.5 2.9e-14 52.7 0.1 3.6 2 0 0 2 2 2 2 Importin-beta N-terminal domain Xpo1 PF08389.7 CAR22707.1 - 0.00046 20.1 6.9 0.037 13.9 0.1 4.5 4 0 0 4 4 4 2 Exportin 1-like protein IF3_N PF05198.11 CAR22707.1 - 0.061 13.2 0.6 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain DUF1912 PF08930.5 CAR22707.1 - 0.13 12.3 1.4 0.4 10.7 0.0 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1912) NAPRTase PF04095.11 CAR22708.1 - 6.4e-65 218.8 0.0 8.4e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 CAR22709.1 - 4.3e-05 23.2 6.7 0.0026 17.5 0.2 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat RNA_pol_N PF01194.12 CAR22710.1 - 2.5e-29 101.0 0.5 2.8e-29 100.9 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit YhfH PF14149.1 CAR22710.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein Chordopox_RPO7 PF05864.7 CAR22710.1 - 0.085 12.9 0.3 0.11 12.5 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Dynamin_N PF00350.18 CAR22711.1 - 7.8e-42 142.9 0.2 2.6e-41 141.2 0.1 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CAR22711.1 - 0.00028 20.8 0.1 0.0038 17.1 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR22711.1 - 0.00079 19.9 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_M PF01031.15 CAR22711.1 - 0.012 14.4 8.1 0.023 13.5 1.7 3.2 2 1 0 2 2 2 0 Dynamin central region AAA_16 PF13191.1 CAR22711.1 - 0.031 14.2 0.4 0.14 12.1 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Linker_histone PF00538.14 CAR22712.1 - 9.3e-20 70.5 0.3 2.9e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family TRF PF08558.5 CAR22713.1 - 1.7e-63 214.1 0.5 2.2e-63 213.7 0.3 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 CAR22713.1 - 1.8e-06 27.8 0.6 3.6e-06 26.9 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR22713.1 - 0.0003 20.8 0.0 0.0007 19.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4037 PF13228.1 CAR22713.1 - 0.035 14.3 0.1 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) WD40 PF00400.27 CAR22714.1 - 1.4e-35 119.8 17.1 5.1e-08 32.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CAR22714.1 - 0.0072 16.0 0.6 1.2 8.7 0.1 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Big_2 PF02368.13 CAR22714.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) YEATS PF03366.11 CAR22715.1 - 6.7e-20 70.5 0.0 1.4e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 YEATS family YEATS PF03366.11 CAR22716.1 - 4.5e-23 80.7 0.2 7.1e-23 80.1 0.1 1.3 1 0 0 1 1 1 1 YEATS family YqeY PF09424.5 CAR22717.1 - 3.6e-24 85.2 2.2 4.2e-24 85.0 1.5 1.2 1 0 0 1 1 1 1 Yqey-like protein GRAB PF10375.4 CAR22718.1 - 3.9e-07 29.4 0.8 9.8e-07 28.1 0.5 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain TMF_DNA_bd PF12329.3 CAR22718.1 - 6.1e-05 22.7 8.7 6.1e-05 22.7 6.0 6.4 3 2 1 5 5 4 1 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 CAR22718.1 - 0.0036 15.8 30.0 0.0036 15.8 20.8 2.8 1 1 2 3 3 3 1 AAA domain CENP-F_leu_zip PF10473.4 CAR22718.1 - 0.0047 16.7 18.1 0.0047 16.7 12.6 4.3 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CAR22718.1 - 0.0099 15.4 27.2 0.0099 15.4 18.8 4.7 1 1 3 4 4 4 1 IncA protein GAS PF13851.1 CAR22718.1 - 0.37 9.9 78.8 0.14 11.3 11.0 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 CAR22718.1 - 0.41 9.7 21.8 0.084 12.0 6.7 3.4 1 1 1 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 CAR22718.1 - 1.7 7.5 84.0 0.02 13.9 14.7 4.0 1 1 3 4 4 4 0 Autophagy protein Apg6 MbeD_MobD PF04899.7 CAR22718.1 - 1.7 8.5 29.7 0.11 12.4 2.5 5.2 3 2 2 5 5 5 0 MbeD/MobD like Bacillus_HBL PF05791.6 CAR22718.1 - 1.9 7.8 34.8 0.18 11.1 8.4 4.2 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Rab5-bind PF09311.6 CAR22718.1 - 2 8.3 77.6 0.11 12.4 10.9 3.4 1 1 2 3 3 3 0 Rabaptin-like protein Filament PF00038.16 CAR22718.1 - 7.1 6.0 70.1 84 2.4 30.6 4.2 1 1 1 2 2 2 0 Intermediate filament protein RFC1 PF08519.7 CAR22719.1 - 1.2e-62 210.2 0.7 2.9e-61 205.7 0.2 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 CAR22719.1 - 4.5e-11 43.0 0.0 1.4e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 CAR22719.1 - 5.6e-10 39.2 0.0 1.6e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 CAR22719.1 - 8.8e-07 27.9 0.1 0.00038 19.2 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CAR22719.1 - 1.3e-06 29.1 0.1 6.3e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAR22719.1 - 0.00015 21.9 0.0 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR22719.1 - 0.00028 20.0 0.0 0.00056 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CAR22719.1 - 0.0014 18.4 0.0 0.04 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR22719.1 - 0.0041 17.4 0.0 0.018 15.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CAR22719.1 - 0.0047 16.5 0.4 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR22719.1 - 0.005 16.8 0.7 0.033 14.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CAR22719.1 - 0.0063 16.2 0.1 0.022 14.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CAR22719.1 - 0.018 14.9 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CAR22719.1 - 0.024 14.7 0.0 0.083 13.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase DPPIV_N PF00930.16 CAR22720.1 - 3.6e-81 272.5 1.2 4.7e-81 272.1 0.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CAR22720.1 - 1.2e-47 161.9 0.0 3.1e-47 160.5 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CAR22720.1 - 7e-08 32.3 0.0 1.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR22720.1 - 2.7e-06 27.4 0.0 4.1e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAR22720.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 CAR22720.1 - 0.0015 18.0 0.0 0.63 9.4 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 CAR22720.1 - 0.041 12.1 0.0 0.26 9.5 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase_phd PF10503.4 CAR22720.1 - 0.14 11.4 0.0 0.86 8.8 0.0 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase Ribosomal_L18p PF00861.17 CAR22721.1 - 1.6e-45 154.1 2.1 5.5e-45 152.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CAR22721.1 - 5.4e-32 110.2 5.1 5.4e-32 110.2 3.5 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DAG_kinase_N PF14513.1 CAR22721.1 - 0.07 13.3 0.5 0.14 12.3 0.4 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Thr_synth_N PF14821.1 CAR22721.1 - 0.11 12.5 0.2 0.7 9.9 0.1 2.5 2 1 0 2 2 2 0 Threonine synthase N terminus CtaG_Cox11 PF04442.9 CAR22724.1 - 1.6e-57 193.5 0.0 2.3e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Zn_clus PF00172.13 CAR22725.1 - 7e-05 22.6 8.4 0.00015 21.6 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mu-like_gpT PF10124.4 CAR22725.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage major head subunit gpT Acyl_transf_1 PF00698.16 CAR22726.1 - 4.5e-05 22.9 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Mito_carr PF00153.22 CAR22727.1 - 3.6e-68 225.3 1.8 4.6e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CAR22727.1 - 0.088 12.8 0.1 0.088 12.8 0.1 2.7 4 1 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family DUF2407_C PF13373.1 CAR22728.1 - 1.2e-39 135.4 1.4 3.4e-39 133.9 1.0 1.8 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 CAR22728.1 - 2.2e-18 66.2 0.1 4.9e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2453 PF10507.4 CAR22728.1 - 0.11 12.3 0.6 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) MTP18 PF10558.4 CAR22729.1 - 6.7e-62 207.8 0.0 7.8e-62 207.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) RNA_pol_Rpb8 PF03870.10 CAR22730.1 - 3e-45 153.7 0.0 3.4e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NifU_N PF01592.11 CAR22731.1 - 8.2e-54 180.9 0.1 9.8e-54 180.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_7 PF13504.1 CAR22732.1 - 0.0069 16.3 1.3 21 5.8 0.0 5.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 CAR22732.1 - 0.022 14.3 18.7 1 9.0 0.0 6.4 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 CAR22732.1 - 0.067 13.7 2.6 1 9.9 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 CAR22732.1 - 0.48 10.6 8.5 3.7 7.9 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeat DUF1691 PF07950.6 CAR22733.1 - 5.4e-29 100.3 0.9 7.8e-17 61.1 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 CAR22733.1 - 0.0045 16.8 4.2 0.39 10.5 0.3 2.5 2 1 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2938 PF11158.3 CAR22733.1 - 0.0091 15.3 0.1 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) PHD PF00628.24 CAR22734.1 - 1.3e-11 44.0 8.4 1.3e-11 44.0 5.8 2.5 3 0 0 3 3 3 1 PHD-finger WD40 PF00400.27 CAR22735.1 - 2.9e-07 30.0 5.4 0.0035 17.1 0.0 3.8 5 0 0 5 5 5 2 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CAR22735.1 - 0.0063 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.20 CAR22736.1 - 4.9e-67 225.8 0.0 6.1e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22736.1 - 6.5e-39 133.5 0.1 1.2e-38 132.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR22736.1 - 6.9e-09 35.0 0.0 1.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR22736.1 - 0.022 14.4 0.0 0.051 13.3 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAR22736.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GrpE PF01025.14 CAR22737.1 - 4e-52 176.1 5.3 4.9e-52 175.8 3.7 1.1 1 0 0 1 1 1 1 GrpE IncA PF04156.9 CAR22737.1 - 0.02 14.4 5.6 0.028 14.0 3.9 1.1 1 0 0 1 1 1 0 IncA protein Foie-gras_1 PF11817.3 CAR22737.1 - 0.078 12.4 2.2 0.12 11.8 1.5 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 FAM75 PF14650.1 CAR22737.1 - 0.14 11.5 2.5 0.18 11.1 1.8 1.1 1 0 0 1 1 1 0 FAM75 family Pkinase PF00069.20 CAR22738.1 - 2.1e-66 223.7 0.0 3.6e-66 222.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22738.1 - 2.8e-38 131.4 0.0 4e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR22738.1 - 3.6e-06 26.1 0.0 6.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR22738.1 - 0.0059 16.3 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAR22738.1 - 0.0074 15.6 0.1 0.018 14.3 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CAR22738.1 - 0.039 13.0 0.0 0.091 11.8 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4407 PF14362.1 CAR22738.1 - 2.1 7.2 8.8 3.9 6.3 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L35Ae PF01247.13 CAR22739.1 - 2.6e-42 142.4 0.9 3e-42 142.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CAR22739.1 - 0.00067 19.5 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain chaperone_DMP PF10448.4 CAR22740.1 - 1.7e-08 34.4 0.0 1.7e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 20S proteasome chaperone DHFR_1 PF00186.14 CAR22741.1 - 9.5e-27 93.5 0.0 2.7e-25 88.8 0.0 2.3 1 1 0 1 1 1 1 Dihydrofolate reductase Oxysterol_BP PF01237.13 CAR22742.1 - 9.1e-93 310.5 1.8 1.1e-92 310.3 1.3 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.6 CAR22743.1 - 2.2e-94 316.6 53.3 2.6e-94 316.4 36.9 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4611 PF15387.1 CAR22743.1 - 1.4 9.0 15.7 0.065 13.3 5.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ABC_membrane_2 PF06472.10 CAR22745.1 - 9.4e-89 297.2 9.6 1.4e-88 296.7 6.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CAR22745.1 - 1.6e-14 54.3 0.0 5.6e-14 52.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CAR22745.1 - 0.00055 19.2 0.2 0.36 10.0 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MobB PF03205.9 CAR22745.1 - 0.011 15.4 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CAR22745.1 - 0.012 15.1 0.1 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 CAR22745.1 - 0.019 14.9 0.1 0.04 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 CAR22745.1 - 0.028 14.1 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain AAA_23 PF13476.1 CAR22745.1 - 0.057 13.7 0.2 0.057 13.7 0.1 2.6 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 CAR22745.1 - 0.057 12.9 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CAR22745.1 - 0.096 12.8 0.0 0.89 9.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CAR22745.1 - 0.097 12.8 0.0 0.3 11.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CAR22745.1 - 0.12 12.2 0.1 0.54 10.2 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.3 CAR22745.1 - 0.12 9.6 0.3 4.5 4.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Mg_chelatase PF01078.16 CAR22745.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF1749 PF08538.5 CAR22746.1 - 2.6e-107 358.2 0.1 3e-107 358.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CAR22746.1 - 9.3e-12 45.3 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR22746.1 - 1.8e-10 40.7 0.0 7.2e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR22746.1 - 4e-06 26.5 0.1 0.0004 19.9 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CAR22746.1 - 6.8e-05 22.1 0.1 0.00059 19.1 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF900 PF05990.7 CAR22746.1 - 0.018 14.3 0.0 0.14 11.4 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 CAR22746.1 - 0.021 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Acetyltransf_1 PF00583.19 CAR22747.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ACPS PF01648.15 CAR22748.1 - 3.8e-15 55.7 0.0 5.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APG5 PF04106.7 CAR22749.1 - 2.9e-46 157.4 0.0 3.8e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.6 CAR22750.1 - 6.7e-43 146.9 21.0 7.2e-39 133.6 6.0 2.7 1 1 1 2 2 2 2 SGT1 protein Pkinase PF00069.20 CAR22751.1 - 1e-65 221.4 0.1 1.8e-65 220.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22751.1 - 2.6e-35 121.7 0.0 4.1e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR22751.1 - 1.6e-07 30.6 0.0 6.1e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Mur_ligase_M PF08245.7 CAR22752.1 - 2.6e-07 30.9 0.1 1.8e-05 24.8 0.1 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CAR22752.1 - 0.0047 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain RRM_1 PF00076.17 CAR22753.1 - 0.0001 21.8 0.1 0.0022 17.6 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR22753.1 - 0.0018 18.1 0.0 0.049 13.4 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR22753.1 - 0.0081 16.1 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.13 CAR22754.1 - 1.2e-62 211.8 0.0 1.1e-58 198.7 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) WD40 PF00400.27 CAR22755.1 - 1.1e-52 174.0 15.7 2.4e-10 39.8 1.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CAR22755.1 - 6.2e-07 28.5 0.1 1.6 7.4 0.0 4.5 1 1 3 5 5 5 4 Nup133 N terminal like Nup160 PF11715.3 CAR22755.1 - 0.0042 15.2 5.2 1 7.4 0.3 4.1 1 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CAR22755.1 - 0.048 13.1 0.3 2.4 7.5 0.0 2.7 2 1 1 3 3 3 0 PQQ-like domain Reg_prop PF07494.6 CAR22755.1 - 0.17 11.9 1.0 6.8 7.0 0.1 2.8 2 0 0 2 2 2 0 Two component regulator propeller MOZ_SAS PF01853.13 CAR22756.1 - 6e-89 296.2 0.5 1e-88 295.5 0.4 1.4 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CAR22756.1 - 1.3e-22 79.2 0.0 2.9e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 CAR22756.1 - 0.024 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PTPA PF03095.10 CAR22757.1 - 3.6e-115 384.2 0.1 4.1e-115 384.0 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAGAT PF03982.8 CAR22758.1 - 5.9e-86 287.8 2.7 2e-74 249.9 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase LicD PF04991.8 CAR22759.1 - 1.2e-30 107.1 8.5 1.2e-30 107.1 5.9 2.8 2 2 0 2 2 2 1 LicD family Pkinase PF00069.20 CAR22760.1 - 5.3e-78 261.7 0.0 8.9e-78 261.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22760.1 - 5e-39 133.9 0.0 7.8e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CAR22760.1 - 2.4e-26 91.6 1.2 1.7e-15 56.8 0.1 3.1 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.1 CAR22760.1 - 5.6e-09 35.3 0.0 9.3e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR22760.1 - 1.7e-05 23.9 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAR22760.1 - 0.00026 20.3 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CAR22760.1 - 0.00032 20.5 0.0 0.011 15.4 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Asp PF00026.18 CAR22761.1 - 2.4e-109 365.4 0.0 3.1e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR22761.1 - 4.1e-12 46.3 0.0 1.1e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CAR22761.1 - 2.6e-05 23.8 0.0 0.00013 21.5 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CAR22761.1 - 5e-05 23.7 0.0 0.013 15.9 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease Kinesin PF00225.18 CAR22762.1 - 1.6e-104 349.2 0.0 2.6e-104 348.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Med9 PF07544.8 CAR22762.1 - 0.0002 21.0 2.7 0.0002 21.0 1.8 3.8 3 1 0 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.1 CAR22762.1 - 0.0037 15.8 1.5 0.0063 15.0 1.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR22762.1 - 0.093 13.5 0.1 0.68 10.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain TMPIT PF07851.8 CAR22762.1 - 0.77 8.7 6.5 3.8 6.4 1.7 2.2 2 0 0 2 2 2 0 TMPIT-like protein V_ATPase_I PF01496.14 CAR22762.1 - 1.7 6.3 5.2 3.5 5.3 3.6 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CAR22762.1 - 3.5 5.9 10.1 0.71 8.2 4.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Peripla_BP_2 PF01497.13 CAR22763.1 - 0.02 14.0 0.0 0.48 9.5 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein NTP_transf_4 PF13562.1 CAR22763.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Methyltransf_15 PF09445.5 CAR22764.1 - 2.9e-57 192.8 0.0 4e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 CAR22764.1 - 7.3e-08 32.1 0.0 9.1e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR22764.1 - 8.2e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CAR22764.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 CAR22764.1 - 1.5e-06 28.7 0.0 2.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR22764.1 - 6.8e-05 23.1 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR22764.1 - 0.001 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR22764.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CAR22764.1 - 0.0029 17.3 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAR22764.1 - 0.0035 16.4 0.0 0.0078 15.3 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 CAR22764.1 - 0.0099 15.2 0.0 0.024 14.0 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.6 CAR22764.1 - 0.032 12.9 0.0 0.056 12.1 0.0 1.3 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase N6_N4_Mtase PF01555.13 CAR22764.1 - 0.069 12.6 0.0 0.2 11.0 0.0 1.8 1 1 1 2 2 2 0 DNA methylase FAA_hydrolase_N PF09298.6 CAR22764.1 - 0.13 12.3 0.1 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Abhydrolase_6 PF12697.2 CAR22766.1 - 7.8e-13 48.8 0.0 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR22766.1 - 1.4e-09 37.8 0.0 3.5e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR22766.1 - 1.5e-08 34.5 0.0 3.4e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CAR22766.1 - 0.0078 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 CAR22766.1 - 0.024 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF915 PF06028.6 CAR22766.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Pet20 PF08692.5 CAR22767.1 - 1.1e-27 96.6 1.2 2.2e-13 50.3 0.0 2.8 2 1 1 3 3 3 2 Mitochondrial protein Pet20 tRNA-synt_1 PF00133.17 CAR22769.1 - 5.4e-43 146.9 0.0 9.5e-35 119.6 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CAR22769.1 - 2.5e-18 65.9 1.8 8.6e-10 37.8 0.0 4.2 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CAR22769.1 - 4.1e-12 46.0 0.1 1.8e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CAR22769.1 - 3.6e-07 29.5 0.0 8.3e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain adh_short PF00106.20 CAR22770.1 - 5.5e-15 55.6 0.2 1.8e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR22770.1 - 0.00012 21.9 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR22770.1 - 0.0019 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CAR22770.1 - 0.0033 16.6 0.2 0.022 13.8 0.2 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 CAR22770.1 - 0.0075 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAR22770.1 - 0.13 12.2 0.0 0.72 9.8 0.0 1.9 1 1 1 2 2 2 0 NADH(P)-binding stn_TNFRSF12A PF12191.3 CAR22771.1 - 0.0011 18.9 0.7 0.01 15.8 0.0 2.6 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Arm PF00514.18 CAR22771.1 - 0.054 13.3 0.1 2.5 8.0 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF3661 PF12400.3 CAR22772.1 - 1.6e-44 151.1 1.6 2.6e-44 150.4 1.1 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein Legionella_OMP PF05150.7 CAR22773.1 - 0.12 11.4 0.3 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor DUF1034 PF06280.7 CAR22773.1 - 5.2 7.5 11.3 0.36 11.2 2.4 2.3 1 1 1 2 2 2 0 Fn3-like domain (DUF1034) MutL_C PF08676.6 CAR22774.1 - 3e-13 49.5 0.2 6.6e-12 45.2 0.1 2.3 1 1 1 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 CAR22774.1 - 6.1e-10 38.8 0.0 9.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAR22774.1 - 4.9e-06 26.2 0.1 1.2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Apc5 PF12862.2 CAR22775.1 - 7.5e-28 96.2 2.3 1.8e-27 95.0 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 CAR22775.1 - 0.0015 18.3 0.3 0.056 13.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR22775.1 - 0.0029 17.2 0.1 0.066 13.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR22775.1 - 0.014 15.9 0.0 0.52 11.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAR22775.1 - 0.094 13.4 0.1 0.37 11.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Clp1 PF06807.9 CAR22776.1 - 2.4e-18 66.6 0.1 3.9e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CAR22776.1 - 0.0007 19.3 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CAR22776.1 - 0.0038 17.2 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CAR22776.1 - 0.0092 16.7 0.0 0.031 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CAR22776.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CAR22776.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 CAR22776.1 - 0.021 15.0 0.1 0.17 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CAR22776.1 - 0.045 13.6 0.0 0.2 11.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Myosin_head PF00063.16 CAR22776.1 - 0.054 11.5 0.0 0.073 11.1 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Septin PF00735.13 CAR22776.1 - 0.06 12.3 0.1 0.51 9.2 0.0 2.1 2 1 0 2 2 2 0 Septin Miro PF08477.8 CAR22776.1 - 0.066 13.7 0.0 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Sigma54_activat PF00158.21 CAR22776.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Rhodanese PF00581.15 CAR22777.1 - 6e-18 65.2 0.0 1.3e-09 38.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SET PF00856.23 CAR22778.1 - 1.3e-08 35.3 0.3 4.9e-07 30.1 0.0 2.3 2 1 0 2 2 2 2 SET domain IRF-2BP1_2 PF11261.3 CAR22778.1 - 0.056 12.8 0.1 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger DNA_pol_B PF00136.16 CAR22780.1 - 1.4e-97 327.4 0.7 2.3e-97 326.7 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CAR22780.1 - 1.5e-20 73.3 0.3 1.2e-10 40.7 0.0 3.1 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CAR22780.1 - 7.1e-14 51.5 12.6 1.6e-13 50.3 8.7 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF2962 PF11176.3 CAR22781.1 - 4.2e-49 166.0 5.6 5e-49 165.8 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Muted PF14942.1 CAR22781.1 - 0.59 9.9 6.0 0.29 11.0 0.2 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Acetyltransf_1 PF00583.19 CAR22783.1 - 1e-14 54.2 1.0 1.4e-14 53.8 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR22783.1 - 5.5e-10 39.2 0.7 7.9e-10 38.7 0.5 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CAR22783.1 - 8.6e-09 35.5 0.4 1e-08 35.3 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CAR22783.1 - 2.8e-07 30.5 0.0 3.4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR22783.1 - 1.6e-06 28.2 0.0 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR22783.1 - 4.8e-06 26.2 0.2 7.6e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CAR22783.1 - 0.0049 16.7 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAR22783.1 - 0.056 13.3 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 CAR22783.1 - 0.088 12.9 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec63 PF02889.11 CAR22784.1 - 1.8e-17 63.5 0.0 1.1e-15 57.7 0.0 2.2 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 CAR22784.1 - 2.1e-16 59.4 0.8 5.6e-16 58.0 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Nop14 PF04147.7 CAR22784.1 - 7.8 4.2 13.1 13 3.5 9.1 1.3 1 0 0 1 1 1 0 Nop14-like family TAP_C PF03943.8 CAR22785.1 - 3.7e-15 55.0 0.0 8.4e-15 53.9 0.0 1.7 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 CAR22785.1 - 3.6e-08 32.8 8.4 2.9e-06 26.7 4.1 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAR22785.1 - 0.00017 21.2 2.5 0.47 10.6 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.1 CAR22785.1 - 0.0002 20.9 1.1 0.00035 20.1 0.8 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.15 CAR22785.1 - 0.019 15.3 1.2 1.8 8.9 0.8 2.8 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain LRR_7 PF13504.1 CAR22785.1 - 0.44 10.9 6.9 4 8.0 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 CAR22785.1 - 3.2 8.1 9.9 15 6.0 0.5 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat Cyt-b5 PF00173.23 CAR22787.1 - 7e-13 48.1 0.0 9.4e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFR_dimer PF04253.10 CAR22788.1 - 4.3e-29 100.6 0.0 8.9e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CAR22788.1 - 0.094 12.4 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 PA domain PIGA PF08288.7 CAR22789.1 - 3.5e-40 136.2 4.1 3.9e-40 136.1 1.4 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CAR22789.1 - 2.4e-28 98.7 0.0 3.7e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CAR22789.1 - 1.5e-14 54.1 0.3 3.6e-14 52.8 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CAR22789.1 - 2.6e-10 40.5 0.0 4.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CAR22789.1 - 2.8e-10 40.5 0.0 5.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 CAR22789.1 - 3.4e-05 23.7 0.4 6.2e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CAR22789.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 CAP_GLY PF01302.20 CAR22790.1 - 1.3e-20 72.8 0.7 2.2e-20 72.1 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain CENP-F_leu_zip PF10473.4 CAR22790.1 - 0.0012 18.7 5.5 0.0012 18.7 3.8 5.6 4 2 2 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CAR22790.1 - 0.003 17.1 6.3 0.003 17.1 4.4 5.0 2 2 2 4 4 4 1 IncA protein DUF573 PF04504.9 CAR22790.1 - 0.39 11.0 4.6 0.85 9.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF573 GAS PF13851.1 CAR22790.1 - 0.42 9.7 47.5 0.17 11.0 5.6 4.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding EF-hand_1 PF00036.27 CAR22791.1 - 3e-25 85.5 15.6 2.2e-07 29.6 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CAR22791.1 - 5.2e-24 84.1 14.4 1.6e-13 50.5 1.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR22791.1 - 1.6e-20 71.1 14.9 9.3e-07 28.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CAR22791.1 - 2.7e-19 68.4 16.5 1.5e-11 43.7 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CAR22791.1 - 6.1e-16 56.9 13.2 1.2e-05 24.3 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CAR22791.1 - 1.7e-06 27.8 0.2 0.052 13.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CAR22791.1 - 2e-06 27.5 1.9 0.0078 15.9 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAR22791.1 - 0.006 16.6 0.6 1.8 8.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region MgtE_N PF03448.12 CAR22791.1 - 0.034 14.4 0.7 0.034 14.4 0.5 2.5 2 1 0 2 2 2 0 MgtE intracellular N domain VCBS PF13517.1 CAR22791.1 - 0.038 14.3 2.6 0.61 10.4 0.0 2.6 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Caleosin PF05042.8 CAR22791.1 - 0.14 11.6 0.5 1 8.9 0.0 2.3 2 2 0 2 2 2 0 Caleosin related protein DcpS_C PF11969.3 CAR22793.1 - 2.3e-15 56.8 2.6 3.1e-14 53.2 1.8 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CAR22793.1 - 5e-15 55.8 0.0 1.3e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 HIT domain zf-C2H2_4 PF13894.1 CAR22793.1 - 0.0018 18.4 2.0 0.005 17.0 1.4 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.10 CAR22793.1 - 0.011 15.4 1.3 0.021 14.5 0.9 1.4 1 0 0 1 1 1 0 BED zinc finger AAA PF00004.24 CAR22794.1 - 1.1e-42 145.3 0.0 2e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CAR22794.1 - 8.6e-07 29.1 0.1 4.9e-05 23.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CAR22794.1 - 1.3e-06 28.1 0.2 3.6e-05 23.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR22794.1 - 1.1e-05 25.4 0.0 3.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CAR22794.1 - 4.2e-05 22.6 0.0 9.1e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CAR22794.1 - 5.4e-05 23.3 0.1 0.0054 16.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR22794.1 - 0.00017 21.2 0.1 0.00036 20.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CAR22794.1 - 0.00043 21.0 0.9 0.0014 19.4 0.1 2.2 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CAR22794.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CAR22794.1 - 0.0015 18.6 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CAR22794.1 - 0.0021 16.8 0.1 0.0039 15.9 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 CAR22794.1 - 0.0033 16.8 0.6 0.029 13.7 0.2 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR22794.1 - 0.0038 16.6 0.1 0.0075 15.6 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CAR22794.1 - 0.0056 15.8 0.2 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CAR22794.1 - 0.0069 16.2 0.4 0.018 14.9 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.1 CAR22794.1 - 0.0079 15.8 0.3 0.022 14.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR22794.1 - 0.0086 16.3 0.2 0.043 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CAR22794.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAR22794.1 - 0.011 15.6 0.6 0.02 14.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 CAR22794.1 - 0.033 13.4 0.9 0.07 12.3 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 CAR22794.1 - 0.038 13.1 1.6 0.093 11.8 0.0 2.4 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 CAR22794.1 - 0.063 12.1 0.1 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 CAR22794.1 - 0.069 12.0 1.6 0.86 8.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 CAR22794.1 - 0.07 12.7 0.1 0.31 10.7 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_3 PF07726.6 CAR22794.1 - 0.073 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CAR22794.1 - 0.11 12.0 1.8 0.86 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CAR22794.1 - 0.12 11.4 0.0 0.12 11.4 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin Fib_alpha PF08702.5 CAR22794.1 - 0.14 12.3 1.3 0.35 10.9 0.9 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 CAR22794.1 - 0.17 12.1 7.1 7.6 6.7 2.1 2.5 2 1 0 2 2 2 0 AAA domain Hexapep PF00132.19 CAR22795.1 - 1.6e-06 27.3 7.9 0.032 13.7 0.4 4.1 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CAR22795.1 - 0.00021 21.4 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 CAR22795.1 - 0.00045 19.5 0.0 0.00089 18.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.7 CAR22795.1 - 0.0036 15.9 2.4 0.034 12.7 0.5 2.1 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.1 CAR22795.1 - 0.18 11.3 16.7 0.93 9.1 6.0 3.7 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase UbiA PF01040.13 CAR22796.1 - 3.1e-22 79.0 17.0 4.9e-22 78.4 11.8 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family MitMem_reg PF13012.1 CAR22797.1 - 4.8e-38 129.7 1.2 7.5e-38 129.1 0.2 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CAR22797.1 - 6.7e-27 93.4 0.0 1.3e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ATP_bind_1 PF03029.12 CAR22798.1 - 1.2e-76 257.3 0.1 1.5e-76 257.0 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CAR22798.1 - 0.0017 17.8 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 CAR22798.1 - 0.0083 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain MMR_HSR1 PF01926.18 CAR22798.1 - 0.0086 16.0 0.0 0.042 13.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CAR22798.1 - 0.011 15.6 0.0 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CAR22798.1 - 0.015 16.0 3.5 0.027 15.3 0.4 2.7 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 CAR22798.1 - 0.039 12.7 0.0 0.07 11.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 CAR22798.1 - 0.1 12.7 0.0 0.32 11.1 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 CAR22798.1 - 0.16 12.2 2.5 1.4 9.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain TBCA PF02970.11 CAR22800.1 - 8.7e-28 96.2 5.4 1.3e-27 95.7 3.7 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A Troponin PF00992.15 CAR22800.1 - 0.0071 16.4 0.7 0.0096 15.9 0.5 1.3 1 1 0 1 1 1 1 Troponin Cytochrom_C_2 PF01322.15 CAR22800.1 - 0.0097 16.4 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C' Fzo_mitofusin PF04799.8 CAR22800.1 - 0.02 14.3 0.6 0.029 13.7 0.3 1.4 1 1 0 1 1 1 0 fzo-like conserved region Hanta_nucleocap PF00846.13 CAR22800.1 - 0.026 13.2 0.9 0.027 13.1 0.6 1.0 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein FliJ PF02050.11 CAR22800.1 - 0.028 14.4 6.0 0.067 13.2 3.9 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein Orthopox_A5L PF06193.6 CAR22800.1 - 0.042 13.8 1.7 0.044 13.7 1.2 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like FlaC_arch PF05377.6 CAR22800.1 - 0.13 12.1 1.8 2.3 8.1 1.2 2.3 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.3 CAR22800.1 - 0.27 10.9 6.1 0.18 11.5 2.5 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spectrin PF00435.16 CAR22800.1 - 0.42 10.9 5.0 2.2 8.5 0.7 2.1 1 1 1 2 2 2 0 Spectrin repeat IncA PF04156.9 CAR22800.1 - 4.3 6.8 7.0 6.4 6.3 4.8 1.3 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 CAR22802.1 - 7.3e-57 192.4 0.1 3.1e-53 180.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22802.1 - 1.4e-18 66.8 0.0 5.1e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR22802.1 - 0.052 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pneumo_att_G PF05539.6 CAR22802.1 - 4.3 6.6 11.4 8 5.7 7.9 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G WD40 PF00400.27 CAR22803.1 - 1.1e-38 129.7 22.5 3.8e-07 29.7 0.8 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CAR22803.1 - 0.00026 19.2 2.9 0.56 8.2 0.2 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 DivIC PF04977.10 CAR22803.1 - 0.0094 15.4 0.2 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.16 CAR22803.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.13 CAR22803.1 - 0.093 12.7 0.3 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.10 CAR22803.1 - 0.27 11.0 3.6 0.46 10.3 2.5 1.2 1 0 0 1 1 1 0 Basic region leucine zipper V_ATPase_I PF01496.14 CAR22804.1 - 3.7e-290 964.1 2.4 4.2e-290 964.0 1.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Rootletin PF15035.1 CAR22804.1 - 0.033 14.1 1.3 0.034 14.1 0.1 1.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Sec3_C_2 PF15278.1 CAR22804.1 - 0.073 13.2 0.7 0.48 10.5 0.2 2.6 1 1 1 2 2 2 0 Sec3 exocyst complex subunit Cortex-I_coil PF09304.5 CAR22804.1 - 0.33 11.0 3.9 8.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil GHMP_kinases_N PF00288.21 CAR22805.1 - 1.3e-23 82.7 0.5 4.2e-23 81.1 0.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAR22805.1 - 7.9e-06 25.9 0.1 3.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Mtc PF03820.12 CAR22806.1 - 3.6e-123 410.1 0.0 4.1e-123 409.9 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF2371 PF10177.4 CAR22806.1 - 0.095 12.5 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Corona_S2 PF01601.11 CAR22806.1 - 0.12 10.3 0.9 1.3 6.9 0.0 2.1 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein WD40 PF00400.27 CAR22807.1 - 4.7e-33 111.8 9.1 4.7e-07 29.4 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 CAR22807.1 - 7.7e-23 80.2 0.1 1.5e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CAR22807.1 - 2.6e-07 29.1 6.2 0.0022 16.2 0.0 3.1 2 2 1 3 3 3 2 Nucleoporin Nup120/160 N2227 PF07942.7 CAR22808.1 - 5.1e-62 209.2 0.0 7e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein MFS_1 PF07690.11 CAR22809.1 - 1.8e-27 95.9 35.7 1.8e-27 95.9 24.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Tubulin_3 PF14881.1 CAR22810.1 - 1.9e-20 73.0 0.0 3.9e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CAR22810.1 - 9.2e-16 57.9 0.2 2.7e-15 56.4 0.1 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 CAR22810.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain IPPT PF01715.12 CAR22811.1 - 1.4e-80 269.9 0.1 1.9e-80 269.5 0.1 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 CAR22811.1 - 3.4e-06 26.4 0.1 5.7e-05 22.4 0.0 2.6 3 0 0 3 3 3 1 Isopentenyl transferase AAA_17 PF13207.1 CAR22811.1 - 2.5e-05 25.0 0.5 6.9e-05 23.6 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR22811.1 - 3.9e-05 23.9 0.2 0.00033 20.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR22811.1 - 0.00016 20.8 0.0 0.0017 17.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CAR22811.1 - 0.00047 20.0 0.0 0.019 14.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CAR22811.1 - 0.0037 17.3 0.1 3.8 7.6 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CAR22811.1 - 0.0042 16.5 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CAR22811.1 - 0.018 15.2 0.1 0.23 11.6 0.0 2.6 3 0 0 3 3 3 0 RNA helicase DUF258 PF03193.11 CAR22811.1 - 0.028 13.6 0.0 0.058 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 CAR22811.1 - 0.079 12.2 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PhoH PF02562.11 CAR22811.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein BRO1 PF03097.13 CAR22812.1 - 2.2e-83 280.0 4.6 3.1e-83 279.6 3.2 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CAR22812.1 - 3.8e-36 124.5 9.3 3.8e-36 124.5 6.5 2.6 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV CTD_bind PF04818.8 CAR22813.1 - 0.0091 16.2 0.3 0.03 14.5 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. FliS PF02561.9 CAR22813.1 - 0.019 14.7 1.7 0.043 13.6 0.3 2.2 2 0 0 2 2 2 0 Flagellar protein FliS Myb_DNA-binding PF00249.26 CAR22814.1 - 4.7e-26 90.5 1.0 3.4e-12 46.2 0.2 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR22814.1 - 1.3e-21 76.4 3.4 1.1e-12 47.8 0.9 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 CAR22814.1 - 2.7e-05 23.5 1.9 2.7e-05 23.5 1.3 2.6 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_4 PF13837.1 CAR22814.1 - 1.2 9.2 9.9 1.8 8.7 0.4 4.0 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain DnaJ PF00226.26 CAR22816.1 - 1.6e-28 98.1 2.0 2.9e-28 97.3 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CAR22816.1 - 3.2e-14 52.7 20.9 4.8e-14 52.1 14.5 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CAR22816.1 - 7.1e-12 45.0 0.0 8.6e-11 41.5 0.0 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain DZR PF12773.2 CAR22816.1 - 0.72 9.7 9.8 1.8 8.4 0.7 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.14 CAR22816.1 - 1.5 8.5 11.7 0.76 9.4 0.7 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Pkinase PF00069.20 CAR22817.1 - 1.3e-43 149.0 0.9 5.5e-24 84.7 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR22817.1 - 3.5e-12 45.9 1.4 2.4e-08 33.3 0.3 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CAR22817.1 - 0.15 10.7 0.2 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RRM_1 PF00076.17 CAR22818.1 - 6.7e-11 41.6 0.0 1.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR22818.1 - 9.2e-09 35.1 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR22818.1 - 9.5e-07 28.5 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR22818.1 - 2.7e-05 23.8 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif GATase PF00117.23 CAR22820.1 - 3.8e-41 140.6 0.0 6.7e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 CAR22820.1 - 4.7e-41 138.4 0.0 9.2e-41 137.4 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 CAR22820.1 - 3.7e-08 33.0 0.0 1.3e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 CAR22820.1 - 5.4e-08 32.0 0.0 1.3e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 CAR22820.1 - 0.0087 14.6 0.0 0.017 13.7 0.0 1.5 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.14 CAR22820.1 - 0.0097 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 CAR22820.1 - 0.011 14.9 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 CAR22820.1 - 0.012 14.6 0.2 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.9 CAR22820.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 CAR22820.1 - 0.05 13.1 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase HEM4 PF02602.10 CAR22821.1 - 3.4e-40 137.7 0.0 3.9e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TRAPPC10 PF12584.3 CAR22822.1 - 1.7e-11 43.8 0.0 3.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 CAR22822.1 - 0.0015 18.0 0.1 0.0027 17.2 0.1 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_3 PF07720.7 CAR22822.1 - 0.092 12.5 0.2 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 CAR22824.1 - 1.4e-14 53.9 0.2 3e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAR22824.1 - 0.0069 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal LAGLIDADG_3 PF14528.1 CAR22825.1 - 0.038 14.2 0.1 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 LAGLIDADG-like domain DUF4570 PF15134.1 CAR22825.1 - 3.9 7.3 6.8 1.7 8.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) MFS_1 PF07690.11 CAR22826.1 - 5.7e-06 25.2 26.0 5.7e-06 25.2 18.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily FSH1 PF03959.8 CAR22827.1 - 1.7e-66 223.6 0.0 2e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CAR22827.1 - 7.9e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR22827.1 - 2.9e-05 24.0 0.0 0.02 14.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CAR22827.1 - 3.2e-05 23.4 0.1 0.00012 21.5 0.1 1.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase UCH PF00443.24 CAR22828.1 - 5.6e-58 196.1 4.6 8.2e-58 195.6 3.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR22828.1 - 2e-25 89.8 6.8 2.7e-25 89.4 4.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CAR22828.1 - 1.3e-10 41.1 9.6 1.3e-10 41.1 6.6 2.9 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RanBP PF00641.13 CAR22828.1 - 7.7 5.7 17.7 4 6.6 2.8 4.4 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others Phosducin PF02114.11 CAR22829.1 - 1.7e-15 56.4 0.8 2.1e-15 56.1 0.5 1.1 1 0 0 1 1 1 1 Phosducin Toprim_3 PF13362.1 CAR22829.1 - 0.87 9.8 3.3 6.2 7.1 0.1 2.7 3 0 0 3 3 3 0 Toprim domain Mre11_DNA_bind PF04152.9 CAR22830.1 - 1.1e-50 171.8 0.2 1.1e-50 171.8 0.1 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CAR22830.1 - 3.3e-29 101.7 1.4 4.7e-29 101.2 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR22830.1 - 5.5e-05 23.0 0.0 0.0003 20.6 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain His_Phos_1 PF00300.17 CAR22831.1 - 1.5e-33 116.1 0.0 1.9e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rhodanese PF00581.15 CAR22832.1 - 1.9e-16 60.4 0.0 2.6e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 CAR22833.1 - 3.4e-14 53.1 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF947 PF06102.7 CAR22834.1 - 4.8e-42 143.6 32.6 4.8e-42 143.6 22.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF947) MRP_L53 PF10780.4 CAR22835.1 - 4e-21 74.7 0.1 5.7e-21 74.2 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Bunya_nucleocap PF00952.12 CAR22835.1 - 0.0082 16.1 0.0 0.0082 16.1 0.0 1.1 1 0 0 1 1 1 1 Bunyavirus nucleocapsid (N) protein Thioredoxin PF00085.15 CAR22836.1 - 2.8e-23 81.5 0.1 6.4e-23 80.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAR22836.1 - 2.7e-05 24.3 0.1 8.4e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAR22836.1 - 6.1e-05 23.0 0.3 0.013 15.6 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CAR22836.1 - 0.0015 18.5 0.2 0.0086 16.0 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CAR22836.1 - 0.0043 16.8 0.7 0.12 12.1 0.2 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CAR22836.1 - 0.0055 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CAR22836.1 - 0.022 14.5 0.1 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.19 CAR22836.1 - 0.042 13.8 0.1 0.098 12.6 0.1 1.7 1 0 0 1 1 1 0 Glutaredoxin DSBA PF01323.15 CAR22836.1 - 0.058 12.9 0.2 0.26 10.8 0.0 2.1 2 1 1 3 3 3 0 DSBA-like thioredoxin domain TraF PF13728.1 CAR22836.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein AMMECR1 PF01871.12 CAR22837.1 - 4.2e-34 117.1 0.0 5.6e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 adh_short PF00106.20 CAR22838.1 - 1.8e-32 112.5 0.0 2.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR22838.1 - 1.3e-13 51.2 0.0 1.6e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR22838.1 - 1e-10 41.5 0.0 1.4e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CAR22838.1 - 3e-06 26.5 0.0 7e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 CAR22838.1 - 2.6e-05 23.7 0.2 0.00016 21.1 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CAR22838.1 - 0.00018 20.5 0.1 0.00028 19.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CAR22838.1 - 0.011 15.5 0.2 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SNF2_N PF00176.18 CAR22839.1 - 2e-84 282.9 0.7 5.2e-84 281.5 0.5 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR22839.1 - 1.2e-17 63.4 0.1 1.3e-15 57.0 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 CAR22839.1 - 3.1e-15 55.8 0.1 1.2e-14 53.9 0.1 2.0 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 CAR22839.1 - 5.5e-13 48.8 0.8 5.5e-13 48.8 0.5 3.8 2 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 CAR22839.1 - 6.6e-05 22.6 4.3 6.6e-05 22.6 3.0 3.6 5 0 0 5 5 5 1 HSA TAFII55_N PF04658.8 CAR22841.1 - 8.2e-56 187.9 0.0 2.3e-55 186.5 0.0 1.8 1 0 0 1 1 1 1 TAFII55 protein conserved region RrnaAD PF00398.15 CAR22842.1 - 8.1e-65 218.4 0.0 9.2e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 CAR22842.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) S1 PF00575.18 CAR22844.1 - 3e-50 168.1 38.1 2.2e-11 43.6 1.1 12.4 12 1 0 12 12 12 9 S1 RNA binding domain TPR_19 PF14559.1 CAR22844.1 - 3.1e-10 40.2 0.0 0.0016 18.7 0.1 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CAR22844.1 - 1.1e-07 31.7 1.2 0.82 10.4 0.2 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAR22844.1 - 3.1e-05 24.5 0.0 2.9 8.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 CAR22844.1 - 7e-05 22.6 0.6 7e-05 22.6 0.4 3.9 1 1 3 4 4 4 2 Suppressor of forked protein (Suf) TPR_12 PF13424.1 CAR22844.1 - 0.0015 18.3 0.1 3.3 7.7 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 CAR22844.1 - 0.022 15.1 0.8 11 6.8 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 CAR22844.1 - 0.024 13.7 2.5 1.2 8.0 0.1 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CAR22844.1 - 0.039 13.7 0.9 0.098 12.4 0.1 2.0 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 CAR22844.1 - 0.055 13.4 0.0 14 5.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_Rbc25 PF08292.7 CAR22844.1 - 2.7 8.2 8.4 1.6 8.9 0.0 4.5 4 0 0 4 4 3 0 RNA polymerase III subunit Rpc25 P5-ATPase PF12409.3 CAR22845.1 - 2.1e-37 127.6 3.5 5e-37 126.3 0.1 2.9 3 0 0 3 3 3 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 CAR22845.1 - 4.3e-26 91.3 0.0 9.5e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CAR22845.1 - 8.9e-26 91.2 0.0 1.8e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR22845.1 - 4e-15 56.8 0.0 5.6e-14 53.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAR22845.1 - 4.1e-06 26.1 0.0 9.6e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 CAR22845.1 - 4.8e-06 26.2 7.5 1.3e-05 24.7 5.2 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 CAR22845.1 - 1.3e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR22845.1 - 0.022 14.3 0.1 0.78 9.2 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mpv17_PMP22 PF04117.7 CAR22846.1 - 5e-20 70.9 0.3 5e-20 70.9 0.2 2.5 2 0 0 2 2 2 1 Mpv17 / PMP22 family S10_plectin PF03501.10 CAR22847.1 - 4.1e-43 145.1 0.4 4.8e-43 144.9 0.3 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 CAR22847.1 - 0.0033 15.6 0.3 0.0038 15.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF505) HTH_45 PF14947.1 CAR22847.1 - 0.04 13.7 0.2 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix tRNA-synt_1c_C PF03950.13 CAR22847.1 - 0.096 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain PadR PF03551.9 CAR22847.1 - 0.2 11.4 3.0 0.23 11.2 0.5 2.1 2 1 0 2 2 2 0 Transcriptional regulator PadR-like family EF-hand_7 PF13499.1 CAR22848.1 - 1.5e-10 41.0 1.0 0.00013 22.0 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR22848.1 - 3.7e-08 32.5 0.7 0.05 13.5 0.0 4.3 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CAR22848.1 - 1.9e-06 26.7 0.0 4 6.9 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CAR22848.1 - 0.00042 19.8 0.2 11 5.7 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CAR22848.1 - 0.011 15.5 0.1 7.7 6.5 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain EF-hand_5 PF13202.1 CAR22848.1 - 0.033 13.5 0.1 6.3 6.3 0.0 3.7 4 0 0 4 4 4 0 EF hand PIN_4 PF13638.1 CAR22849.1 - 0.00045 20.3 0.0 0.0052 16.8 0.0 2.4 1 1 1 2 2 2 1 PIN domain FA_hydroxylase PF04116.8 CAR22850.1 - 1.2e-16 61.0 19.9 1.2e-16 61.0 13.8 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2219 PF09982.4 CAR22850.1 - 0.07 11.9 0.2 0.15 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2219) GATase_5 PF13507.1 CAR22851.1 - 1.1e-98 329.3 0.1 1.8e-98 328.5 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CAR22851.1 - 4.3e-46 156.7 0.1 2.8e-27 95.5 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CAR22851.1 - 1e-21 76.9 0.1 7.9e-21 74.1 0.0 2.6 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain DUF2462 PF09495.5 CAR22852.1 - 3.4e-19 69.3 11.3 4.1e-19 69.1 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) 60KD_IMP PF02096.15 CAR22853.1 - 6.7e-14 52.0 5.4 1.6e-12 47.5 3.7 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.8 CAR22854.1 - 9.7e-29 99.0 0.4 1.1e-28 98.8 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-TFIIB PF13453.1 CAR22854.1 - 0.025 13.7 0.5 0.04 13.1 0.4 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Toxin_19 PF08088.7 CAR22854.1 - 6 6.8 6.8 0.91 9.4 0.2 2.3 2 0 0 2 2 2 0 Conotoxin I-superfamily Glutaredoxin PF00462.19 CAR22855.1 - 6.5e-07 29.2 0.0 1.7e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 CAR22855.1 - 0.00024 20.6 0.0 0.00026 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CAR22855.1 - 0.013 15.7 0.2 0.14 12.3 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CAR22855.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin PF00085.15 CAR22855.1 - 0.025 14.2 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF953 PF06110.6 CAR22855.1 - 0.04 13.3 0.6 0.051 13.0 0.4 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 CAR22855.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 CAR22855.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin MFS_1 PF07690.11 CAR22856.1 - 5.1e-22 78.0 20.3 5.1e-22 78.0 14.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S8 PF00410.14 CAR22857.1 - 2.6e-26 91.9 0.1 3.5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Arrestin_C PF02752.17 CAR22858.1 - 4.4e-21 75.3 0.1 1.9e-20 73.3 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CAR22858.1 - 5.3e-09 36.0 0.1 1.6e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain F-box PF00646.28 CAR22859.1 - 1.5e-08 34.1 2.1 2.1e-08 33.5 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CAR22859.1 - 2.2e-07 30.4 0.5 1.3e-06 27.9 0.3 2.4 2 0 0 2 2 2 1 F-box-like HSP70 PF00012.15 CAR22860.1 - 5.6e-216 718.1 11.3 6.4e-216 717.9 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR22860.1 - 3e-19 68.7 1.4 1.3e-15 56.8 0.2 2.7 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CAR22860.1 - 0.0012 18.5 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF948 PF06103.6 CAR22860.1 - 1.4 8.8 7.5 4.8 7.1 0.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) P21-Arc PF04062.9 CAR22861.1 - 5.4e-81 270.5 0.1 6e-81 270.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNH PF00780.17 CAR22862.1 - 2.5e-75 253.4 0.1 5.1e-75 252.4 0.1 1.5 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CAR22862.1 - 2.1e-40 137.7 0.3 1.8e-39 134.7 0.1 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 CAR22862.1 - 7.9e-33 113.8 2.7 2.7e-32 112.0 0.1 2.6 3 0 0 3 3 3 1 RhoGEF domain DEP PF00610.16 CAR22862.1 - 4.6e-13 48.7 0.0 1.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FlgN PF05130.7 CAR22862.1 - 0.21 11.8 3.3 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 FlgN protein ELO PF01151.13 CAR22863.1 - 2.7e-60 203.7 24.5 3.4e-60 203.4 17.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-C2H2_jaz PF12171.3 CAR22864.1 - 0.00059 19.8 1.2 0.11 12.6 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CAR22864.1 - 0.0013 18.9 2.2 0.0013 18.9 1.5 4.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR22864.1 - 0.0026 18.0 2.2 0.0026 18.0 1.5 5.1 5 1 0 5 5 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR22864.1 - 0.0051 17.0 4.0 0.0051 17.0 2.8 4.9 4 1 1 5 5 5 1 Zinc-finger double domain zf-SNAP50_C PF12251.3 CAR22864.1 - 0.083 12.2 0.3 0.083 12.2 0.2 2.0 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal zf-C2H2_6 PF13912.1 CAR22864.1 - 0.14 12.0 0.1 0.14 12.0 0.1 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 CAR22864.1 - 0.29 10.6 0.1 0.29 10.6 0.1 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_1 PF14446.1 CAR22864.1 - 0.53 10.0 4.1 25 4.7 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DZR PF12773.2 CAR22864.1 - 1 9.2 5.8 4.3 7.2 0.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.7 CAR22864.1 - 1.6 8.8 10.9 1.2 9.2 4.9 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2256 PF10013.4 CAR22864.1 - 2.6 7.8 8.9 24 4.7 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.5 CAR22864.1 - 9.1 6.3 7.1 81 3.2 0.3 3.5 3 0 0 3 3 3 0 Zinc ribbon domain FA_desaturase PF00487.19 CAR22865.1 - 7.4e-25 87.8 24.7 1e-24 87.4 17.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CAR22865.1 - 2e-07 31.0 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) KRE9 PF05390.6 CAR22867.1 - 6.8e-35 119.6 8.2 1.2e-34 118.8 5.7 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CAR22867.1 - 5.6e-14 52.3 0.9 6.8e-13 48.9 0.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fn_bind PF02986.9 CAR22867.1 - 0.069 12.6 0.0 0.92 9.0 0.0 2.3 2 0 0 2 2 2 0 Fibronectin binding repeat La PF05383.12 CAR22868.1 - 3e-23 81.3 0.0 5.8e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CAR22868.1 - 5.8e-08 32.2 0.2 2e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR22868.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR22868.1 - 0.091 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IstB_IS21 PF01695.12 CAR22869.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Aldo_ket_red PF00248.16 CAR22870.1 - 1.3e-40 139.0 0.0 1.6e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acyltransferase PF01553.16 CAR22871.1 - 1.8e-35 121.2 0.0 3.1e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ThiS PF02597.15 CAR22871.1 - 0.37 11.2 2.5 0.95 9.9 1.7 1.7 1 0 0 1 1 1 0 ThiS family FBPase PF00316.15 CAR22872.1 - 1.2e-135 451.5 0.0 1.3e-135 451.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Pepsin-I3 PF06394.8 CAR22872.1 - 0.024 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain MFS_1 PF07690.11 CAR22874.1 - 2.3e-15 56.1 27.9 2.3e-15 56.1 19.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily ZYG-11_interact PF05884.7 CAR22874.1 - 0.2 10.6 5.1 0.037 13.1 0.7 1.8 2 0 0 2 2 2 0 Interactor of ZYG-11 SecY PF00344.15 CAR22875.1 - 2.7e-89 299.4 13.2 3.5e-89 299.1 9.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CAR22875.1 - 8e-19 66.8 0.6 5.7e-18 64.1 0.1 2.8 2 0 0 2 2 2 1 Plug domain of Sec61p Transp_cyt_pur PF02133.10 CAR22876.1 - 2.9e-155 517.1 37.2 3.3e-155 516.9 25.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PIRT PF15099.1 CAR22876.1 - 0.086 12.0 0.4 0.2 10.8 0.3 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family NTP_transferase PF00483.18 CAR22877.1 - 2.4e-49 167.8 0.0 3.3e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CAR22877.1 - 7.9e-11 42.2 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 CAR22877.1 - 4.3e-09 35.4 5.5 7.3e-07 28.4 1.4 3.3 1 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CAR22877.1 - 0.0017 17.8 3.2 0.037 13.5 0.2 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 CAR22877.1 - 0.069 12.6 0.0 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 CAR22877.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase Ank_2 PF12796.2 CAR22878.1 - 1.8e-13 50.6 1.7 1.3e-08 35.0 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAR22878.1 - 7.8e-13 48.2 0.8 9.3e-06 25.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAR22878.1 - 2.4e-12 47.0 0.5 6.6e-05 23.3 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CAR22878.1 - 8.3e-10 37.9 0.8 0.00014 21.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 CAR22878.1 - 9.6e-08 31.5 0.6 0.019 15.1 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 CAR22878.1 - 4e-07 29.6 1.6 1.1e-06 28.2 0.1 2.4 2 1 0 2 2 2 1 KilA-N domain Y_phosphatase3 PF13350.1 CAR22879.1 - 2.6e-45 154.6 0.0 6.6e-45 153.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_5 PF12695.2 CAR22879.1 - 8.8e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR22879.1 - 1.6e-08 34.7 0.0 5.4e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3C PF13348.1 CAR22879.1 - 1.6e-06 28.1 0.0 3.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Hydrolase_4 PF12146.3 CAR22879.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase CRAL_TRIO PF00650.15 CAR22880.1 - 3.6e-44 150.0 0.0 5.5e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR22880.1 - 5.5e-14 52.0 0.3 2e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CAR22880.1 - 7.1e-09 35.7 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CENP-I PF07778.6 CAR22881.1 - 3.4e-17 61.8 6.4 3.3e-15 55.2 0.4 2.5 3 0 0 3 3 3 2 Mis6 tRNA-synt_1 PF00133.17 CAR22882.1 - 3e-55 187.3 0.1 2.5e-34 118.2 1.0 6.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 CAR22882.1 - 9.8e-42 142.3 0.0 1.5e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 CAR22882.1 - 2e-24 86.0 1.2 7e-20 71.0 0.1 4.2 4 1 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CAR22882.1 - 2e-05 24.4 0.4 4.9e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 CAR22882.1 - 4.7e-05 22.3 0.0 7.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DNA_ligase_ZBD PF03119.11 CAR22882.1 - 0.016 14.8 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1c PF00749.16 CAR22882.1 - 0.022 13.4 0.2 4 5.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Pox_A_type_inc PF04508.7 CAR22882.1 - 0.14 11.9 0.1 0.47 10.3 0.1 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SMC_N PF02463.14 CAR22883.1 - 2.1e-18 66.3 22.0 2.7e-17 62.7 15.3 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR22883.1 - 6.8e-10 39.6 29.5 6.8e-10 39.6 20.4 4.9 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.1 CAR22883.1 - 7.5e-07 28.5 11.6 7.5e-07 28.5 8.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain WEMBL PF05701.6 CAR22883.1 - 7.2e-06 24.7 18.1 7.2e-06 24.7 12.6 2.5 2 1 0 2 2 2 1 Weak chloroplast movement under blue light AAA_21 PF13304.1 CAR22883.1 - 6.3e-05 23.0 20.4 0.0089 16.0 0.4 3.7 3 1 0 3 3 3 2 AAA domain Spc7 PF08317.6 CAR22883.1 - 0.00012 20.9 5.1 0.00012 20.9 3.5 4.9 2 2 2 4 4 4 2 Spc7 kinetochore protein AAA_29 PF13555.1 CAR22883.1 - 0.00081 18.8 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CAR22883.1 - 0.13 12.5 0.1 0.13 12.5 0.1 4.9 3 2 1 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 CAR22883.1 - 0.56 9.3 16.4 1.1 8.3 0.2 4.2 2 2 2 4 4 4 0 Reovirus sigma C capsid protein Uso1_p115_head PF04869.9 CAR22884.1 - 2e-91 306.0 3.2 1.3e-90 303.3 2.3 2.5 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 CAR22884.1 - 5e-11 42.6 25.9 5e-11 42.6 18.0 10.6 1 1 8 10 10 10 1 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.7 CAR22884.1 - 0.006 16.3 27.1 0.006 16.3 18.8 11.4 1 1 10 11 11 11 1 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 CAR22884.1 - 1.1 6.9 253.6 2.9 5.4 30.5 4.8 1 1 2 3 3 3 0 Myosin tail Rad52_Rad22 PF04098.10 CAR22885.1 - 1.5e-34 118.9 0.2 1.9e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein IKI3 PF04762.7 CAR22886.1 - 0 1107.8 0.0 0 1107.6 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Vac14_Fig4_bd PF11916.3 CAR22888.1 - 3.1e-74 248.0 6.0 3.1e-74 248.0 4.2 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CAR22888.1 - 5.4e-46 154.9 5.1 2.6e-38 130.3 0.0 5.5 7 0 0 7 7 7 3 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CAR22888.1 - 2e-12 46.1 2.3 0.00023 20.9 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 CAR22888.1 - 1e-07 32.1 1.9 0.063 13.5 0.0 4.8 5 0 0 5 5 5 3 HEAT repeats Cnd1 PF12717.2 CAR22888.1 - 2.5e-07 30.7 6.1 0.021 14.6 0.5 4.5 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CAR22888.1 - 2e-05 24.8 1.7 0.29 11.6 0.0 5.1 6 0 0 6 6 6 2 HEAT-like repeat RasGEF_N_2 PF14663.1 CAR22888.1 - 0.047 13.6 0.2 0.047 13.6 0.2 4.3 6 0 0 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3730 PF12530.3 CAR22888.1 - 0.13 12.1 10.5 3.3 7.5 5.5 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3730) zf-C2H2_2 PF12756.2 CAR22889.1 - 5.4e-32 109.9 1.6 1.2e-28 99.1 0.1 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CAR22889.1 - 0.019 15.1 4.4 0.093 12.9 0.8 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 CAR22889.1 - 3.5 7.3 12.0 0.87 9.3 0.2 3.3 4 0 0 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) DUF663 PF04950.7 CAR22890.1 - 2.3e-100 335.3 0.0 4.1e-100 334.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CAR22890.1 - 7.9e-27 92.6 0.1 1.6e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ribosomal_S14 PF00253.16 CAR22891.1 - 8.7e-20 69.8 3.9 9.5e-20 69.7 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 CAR22891.1 - 0.33 11.0 3.8 5.2 7.2 0.2 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Peptidase_M16 PF00675.15 CAR22892.1 - 9.1e-39 132.5 0.5 5.4e-38 130.0 0.0 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR22892.1 - 5.8e-32 110.8 0.9 3.8e-21 75.5 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF4600 PF15372.1 CAR22894.1 - 0.64 10.2 3.6 8.6 6.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) UQ_con PF00179.21 CAR22895.1 - 1.4e-43 147.6 0.1 1.6e-43 147.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR22895.1 - 2.2e-05 24.1 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CAR22895.1 - 0.13 12.1 2.3 0.26 11.2 1.6 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 CAR22896.1 - 1.9e-57 194.7 6.6 1.9e-57 194.7 4.6 1.4 1 1 0 1 1 1 1 Pex19 protein family XPC-binding PF09280.6 CAR22896.1 - 0.013 14.9 2.0 0.02 14.3 0.0 2.4 3 0 0 3 3 3 0 XPC-binding domain DUF937 PF06078.6 CAR22896.1 - 0.093 12.9 7.9 1.2 9.3 4.9 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Z1 PF10593.4 CAR22896.1 - 0.13 11.4 0.9 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Z1 domain Cytochrom_B562 PF07361.6 CAR22896.1 - 0.93 9.9 10.3 4.8 7.6 0.7 3.3 3 1 0 3 3 3 0 Cytochrome b562 Occludin_ELL PF07303.8 CAR22896.1 - 5.5 7.7 6.9 34 5.2 0.1 2.8 3 0 0 3 3 3 0 Occludin homology domain CFEM PF05730.6 CAR22897.1 - 3.9e-09 36.2 13.6 1.1e-08 34.7 9.4 1.8 1 0 0 1 1 1 1 CFEM domain Spc7_N PF15402.1 CAR22897.1 - 0.65 7.9 37.0 0.78 7.6 25.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF605 PF04652.11 CAR22897.1 - 2.7 7.2 43.1 3.5 6.9 29.9 1.1 1 0 0 1 1 1 0 Vta1 like Arrestin_N PF00339.24 CAR22898.1 - 1.4e-09 37.9 0.1 1.3e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.9 CAR22899.1 - 1.2e-82 277.0 0.0 1.4e-82 276.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Iso_dh PF00180.15 CAR22901.1 - 1.3e-63 215.1 0.0 1.5e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COX7C PF02935.11 CAR22902.1 - 5e-20 71.0 1.3 5.6e-20 70.9 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF336 PF03928.9 CAR22904.1 - 6.9e-20 71.1 0.0 9e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Sec1 PF00995.18 CAR22905.1 - 9.9e-65 219.2 0.0 1.5e-64 218.6 0.0 1.3 1 1 0 1 1 1 1 Sec1 family AAA PF00004.24 CAR22906.1 - 3.5e-89 295.8 0.0 3.4e-44 150.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR22906.1 - 2.8e-13 49.4 0.0 6.5e-06 25.3 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAR22906.1 - 3.8e-13 49.8 0.3 3.2e-07 30.5 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CAR22906.1 - 2.5e-11 43.8 0.3 8.9e-05 22.6 0.0 4.6 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CAR22906.1 - 1.1e-10 41.4 0.0 0.00051 19.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR22906.1 - 3.4e-09 36.8 0.0 0.0021 17.9 0.0 3.3 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CAR22906.1 - 8e-09 35.4 0.0 0.00022 21.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CAR22906.1 - 5.9e-08 31.8 0.4 0.0049 15.6 0.0 3.1 3 0 0 3 3 3 2 TIP49 C-terminus AAA_33 PF13671.1 CAR22906.1 - 6.2e-07 29.3 0.0 0.00067 19.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CAR22906.1 - 2.1e-06 28.5 0.1 0.021 15.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CAR22906.1 - 1.8e-05 23.9 0.0 0.12 11.4 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 CAR22906.1 - 3.1e-05 23.2 0.2 0.088 11.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CAR22906.1 - 3.4e-05 23.9 0.0 0.29 11.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 CAR22906.1 - 3.7e-05 23.3 5.2 0.0016 18.1 0.0 3.5 4 0 0 4 4 3 1 Part of AAA domain Sigma54_activ_2 PF14532.1 CAR22906.1 - 4.7e-05 23.4 0.0 0.061 13.3 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 CAR22906.1 - 5.3e-05 23.2 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CAR22906.1 - 6.7e-05 22.5 0.2 0.019 14.6 0.0 3.7 4 0 0 4 4 4 1 NACHT domain Bac_DnaA PF00308.13 CAR22906.1 - 9.6e-05 22.1 0.0 0.016 14.8 0.0 2.8 2 1 0 2 2 2 1 Bacterial dnaA protein IstB_IS21 PF01695.12 CAR22906.1 - 0.00021 20.7 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 CAR22906.1 - 0.00023 20.6 5.7 1.2 8.4 0.1 4.3 2 2 1 3 3 3 2 AAA domain CDC48_N PF02359.13 CAR22906.1 - 0.00096 19.0 1.0 0.0027 17.6 0.3 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.6 CAR22906.1 - 0.0013 18.3 0.0 1.8 8.1 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAR22906.1 - 0.0018 17.0 0.0 0.088 11.4 0.0 2.5 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 CAR22906.1 - 0.0028 17.2 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CAR22906.1 - 0.0048 17.1 0.0 0.38 11.0 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA_18 PF13238.1 CAR22906.1 - 0.012 15.9 0.0 0.51 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CAR22906.1 - 0.018 14.5 0.0 17 4.8 0.0 3.7 3 1 0 3 3 3 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 CAR22906.1 - 0.02 14.6 0.0 3.3 7.3 0.0 2.9 2 2 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 CAR22906.1 - 0.032 13.8 0.1 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 CAR22906.1 - 0.032 13.7 0.0 0.32 10.4 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CAR22906.1 - 0.032 13.1 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 CAR22906.1 - 0.044 13.4 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 CAR22906.1 - 0.054 12.6 0.6 15 4.6 0.1 3.2 2 1 1 3 3 3 0 KaiC AFG1_ATPase PF03969.11 CAR22906.1 - 0.059 12.1 0.0 0.22 10.2 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase DUF815 PF05673.8 CAR22906.1 - 0.061 12.2 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 CAR22906.1 - 0.078 12.5 0.5 0.54 9.8 0.0 2.6 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 CAR22906.1 - 0.078 12.6 0.7 2.1 8.0 0.0 3.2 2 2 2 4 4 4 0 NTPase Synthase_beta PF11421.3 CAR22907.1 - 4.7 7.9 6.6 0.71 10.5 0.5 2.4 3 0 0 3 3 3 0 ATP synthase F1 beta subunit DSHCT PF08148.7 CAR22908.1 - 7.3e-61 204.5 1.5 1.1e-60 203.9 0.2 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CAR22908.1 - 2.7e-22 79.0 0.0 7.8e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR22908.1 - 1.7e-07 30.9 0.0 4.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 CAR22908.1 - 1.1e-06 27.9 0.1 3e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 CAR22908.1 - 0.0023 17.8 0.1 0.017 14.9 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit C1_3 PF07649.7 CAR22908.1 - 0.49 10.4 1.3 16 5.6 0.1 2.3 2 0 0 2 2 2 0 C1-like domain Bromodomain PF00439.20 CAR22909.1 - 6.7e-40 134.8 0.5 5e-19 68.0 0.0 2.5 2 0 0 2 2 2 2 Bromodomain DUF4094 PF13334.1 CAR22909.1 - 0.27 11.6 2.9 0.4 11.0 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Bap31 PF05529.7 CAR22910.1 - 3.1e-45 153.9 12.7 3.2e-44 150.6 8.8 2.0 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF2730 PF10805.3 CAR22910.1 - 0.043 13.5 0.2 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DivIC PF04977.10 CAR22910.1 - 0.052 13.0 0.7 0.14 11.6 0.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Topoisom_I PF01028.15 CAR22910.1 - 0.056 12.5 0.1 0.089 11.8 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Dus PF01207.12 CAR22911.1 - 9.5e-45 152.7 0.0 1.9e-34 118.9 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CAR22911.1 - 0.00031 20.3 6.3 0.003 17.2 0.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAR22911.1 - 2 8.5 4.8 0.35 10.9 0.2 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-C2H2_4 PF13894.1 CAR22912.1 - 0.00067 19.8 16.1 0.054 13.8 0.3 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR22912.1 - 0.044 14.0 1.1 0.044 14.0 0.8 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 CAR22912.1 - 0.053 13.8 20.2 0.07 13.5 0.7 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CAR22912.1 - 0.15 12.2 0.1 0.15 12.2 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding DUF1297 PF06973.7 CAR22913.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) DUF1765 PF08578.5 CAR22914.1 - 2.7e-14 53.3 8.0 6.6e-14 52.0 5.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) BRE1 PF08647.6 CAR22915.1 - 2.6e-28 97.8 14.8 2.6e-28 97.8 10.3 7.0 5 2 2 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 CAR22915.1 - 4.8e-07 29.3 10.8 8.2e-07 28.5 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR22915.1 - 7.2e-07 29.1 13.5 1.4e-06 28.2 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR22915.1 - 4.1e-05 23.2 13.7 7.4e-05 22.3 9.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAR22915.1 - 5.9e-05 22.6 14.3 0.00011 21.7 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR22915.1 - 0.00051 19.8 10.9 0.001 18.8 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CAR22915.1 - 0.0076 15.7 5.8 0.018 14.5 4.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C2H2 PF00096.21 CAR22915.1 - 0.046 14.0 0.0 0.046 14.0 0.0 2.8 3 0 0 3 3 1 0 Zinc finger, C2H2 type zf-RING_UBOX PF13445.1 CAR22915.1 - 0.053 13.2 7.7 0.18 11.5 5.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 CAR22915.1 - 0.067 12.9 4.6 0.14 11.9 3.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CAR22915.1 - 0.91 9.1 11.2 1.8 8.1 7.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CAR22915.1 - 1.5 8.7 10.4 3.3 7.6 7.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Dus PF01207.12 CAR22916.1 - 4.8e-81 271.9 0.0 5.9e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.20 CAR22916.1 - 0.15 10.8 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Ribosomal_L31e PF01198.14 CAR22917.1 - 2.1e-38 129.8 1.3 2.5e-38 129.6 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Rxt3 PF08642.5 CAR22918.1 - 2.7e-30 104.9 0.0 6.4e-30 103.7 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 CAR22918.1 - 0.0064 16.4 0.0 0.14 12.1 0.0 2.4 1 1 0 1 1 1 1 LCCL domain DUF4050 PF13259.1 CAR22919.1 - 1.3e-19 70.2 1.6 2.4e-19 69.4 1.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) GCN5L1 PF06320.8 CAR22920.1 - 8.7e-05 22.3 1.7 0.00015 21.6 1.2 1.4 1 1 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF1542 PF07564.6 CAR22920.1 - 0.027 14.4 1.5 0.041 13.9 1.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Vps39_1 PF10366.4 CAR22921.1 - 2.8e-31 107.7 0.4 2.8e-31 107.7 0.3 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CAR22921.1 - 1.4e-18 66.9 0.8 5.3e-18 65.2 0.6 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Utp21 PF04192.7 CAR22922.1 - 9.6e-78 260.5 1.0 1.5e-77 259.8 0.7 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CAR22922.1 - 1.8e-18 65.6 17.1 1.8e-08 33.9 0.9 8.6 9 1 0 9 9 9 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CAR22922.1 - 0.00068 19.1 0.4 0.6 9.5 0.0 3.6 3 1 1 4 4 4 2 PQQ-like domain Cytochrom_D1 PF02239.11 CAR22922.1 - 0.00077 17.8 0.0 0.0078 14.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain CPSF_A PF03178.10 CAR22922.1 - 0.0008 18.5 0.5 0.0069 15.5 0.1 2.5 2 1 1 3 3 3 1 CPSF A subunit region Apc4_WD40 PF12894.2 CAR22922.1 - 0.13 11.8 0.0 13 5.4 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain His_Phos_2 PF00328.17 CAR22923.1 - 2.2e-131 438.3 0.3 3e-131 437.8 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CAR22923.1 - 5.8e-09 35.7 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CAR22923.1 - 0.046 13.5 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Ctr PF04145.10 CAR22924.1 - 2.5e-40 137.8 0.5 3.5e-40 137.3 0.3 1.2 1 0 0 1 1 1 1 Ctr copper transporter family NUDIX_4 PF14815.1 CAR22924.1 - 0.031 13.6 0.1 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain Glycos_transf_4 PF00953.16 CAR22924.1 - 0.095 12.4 4.4 0.2 11.4 2.9 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 4 Pribosyl_synth PF14572.1 CAR22925.1 - 2.5e-42 144.7 1.8 9.2e-34 116.7 0.2 2.2 1 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CAR22925.1 - 8.6e-40 135.1 0.0 3.4e-38 129.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CAR22925.1 - 9.7e-07 28.5 0.2 2.5e-05 23.9 0.2 2.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SRR1 PF07985.7 CAR22926.1 - 5.1e-16 58.3 0.0 9.7e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 SRR1 Acyl_transf_1 PF00698.16 CAR22927.1 - 1e-94 317.4 0.0 1.9e-93 313.2 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CAR22927.1 - 1e-37 128.2 0.0 2.1e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 CAR22927.1 - 1.7e-29 101.3 0.1 9e-29 99.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 CAR22927.1 - 3.6e-15 55.9 0.0 1.5e-14 53.9 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 CAR22927.1 - 0.052 12.6 0.1 0.66 9.0 0.1 2.7 1 1 0 1 1 1 0 Nitronate monooxygenase Voldacs PF03517.8 CAR22928.1 - 9.3e-13 48.1 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.11 CAR22929.1 - 4.3e-77 258.6 0.0 5.7e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CAR22929.1 - 2.8e-31 107.6 0.2 5.4e-31 106.7 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain GATA PF00320.22 CAR22930.1 - 4.6e-07 29.0 8.9 4.6e-07 29.0 6.2 3.1 3 0 0 3 3 3 1 GATA zinc finger Mtr2 PF10429.4 CAR22931.1 - 3e-62 209.2 0.0 3.4e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Abhydrolase_6 PF12697.2 CAR22932.1 - 9.6e-24 84.5 0.0 1.3e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR22932.1 - 2.2e-14 53.5 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR22932.1 - 4.6e-10 39.4 0.0 8.7e-10 38.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 CAR22932.1 - 0.046 13.6 0.1 0.087 12.7 0.1 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Ndr PF03096.9 CAR22932.1 - 0.087 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family SUR7 PF06687.7 CAR22933.1 - 2e-21 76.5 17.4 3.4e-20 72.5 12.1 2.3 1 1 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.18 CAR22933.1 - 0.0047 16.7 2.5 0.0047 16.7 1.7 2.9 3 1 1 4 4 4 1 Membrane-associating domain Fig1 PF12351.3 CAR22933.1 - 0.012 15.5 8.6 0.012 15.5 6.0 3.4 4 1 1 5 5 5 0 Ca2+ regulator and membrane fusion protein Fig1 GAT PF03127.9 CAR22933.1 - 0.24 11.3 6.5 0.98 9.4 0.1 3.7 3 1 1 4 4 4 0 GAT domain SUR7 PF06687.7 CAR22934.1 - 3.8e-40 137.7 15.9 4.5e-40 137.4 11.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family PIRT PF15099.1 CAR22934.1 - 0.16 11.2 1.3 0.25 10.5 0.3 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Polysacc_synt_C PF14667.1 CAR22934.1 - 2.7 7.8 15.4 1.8 8.3 7.3 2.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain ABC_membrane_2 PF06472.10 CAR22935.1 - 2.2e-61 207.4 7.9 3.9e-60 203.3 5.5 2.1 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CAR22935.1 - 3.2e-17 63.1 0.0 7.4e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CAR22935.1 - 7.2e-05 22.8 0.0 0.00018 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CAR22935.1 - 0.0069 16.7 1.3 0.028 14.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CAR22935.1 - 0.018 14.2 0.1 0.14 11.3 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR22935.1 - 0.019 14.4 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CAR22935.1 - 0.062 13.2 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain COX5A PF02284.11 CAR22935.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va DUF258 PF03193.11 CAR22935.1 - 0.095 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 CAR22935.1 - 0.12 11.5 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI EAP30 PF04157.11 CAR22936.1 - 4e-38 130.7 0.5 1.9e-37 128.5 0.3 2.0 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CAR22936.1 - 2.4e-28 97.7 0.1 5.3e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 CAR22936.1 - 0.00013 21.3 0.0 0.00038 19.9 0.0 1.8 1 1 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 CAR22936.1 - 0.012 15.1 0.2 0.012 15.1 0.2 2.9 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger bPH_3 PF14470.1 CAR22936.1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain zf-RanBP PF00641.13 CAR22936.1 - 0.03 13.4 7.1 0.48 9.5 1.2 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others OrfB_Zn_ribbon PF07282.6 CAR22936.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.2 CAR22936.1 - 0.92 9.3 7.0 0.6 9.9 0.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon Mo25 PF08569.6 CAR22937.1 - 1.1e-116 389.5 6.0 1.3e-116 389.3 4.2 1.0 1 0 0 1 1 1 1 Mo25-like OB_NTP_bind PF07717.11 CAR22938.1 - 4e-19 68.5 0.0 1.1e-18 67.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 CAR22938.1 - 2.7e-12 46.5 3.5 5.1e-12 45.6 1.6 2.2 2 0 0 2 2 2 1 RWD domain Helicase_C PF00271.26 CAR22938.1 - 3.6e-11 42.7 0.1 8.5e-11 41.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR22938.1 - 3.7e-10 39.5 0.2 1.6e-09 37.4 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.18 CAR22938.1 - 1.3e-09 37.9 0.2 4.5e-09 36.2 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) AAA_19 PF13245.1 CAR22938.1 - 0.00011 21.8 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 CAR22938.1 - 0.00026 20.4 0.0 0.00063 19.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 CAR22938.1 - 0.0018 17.1 0.0 0.0037 16.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 CAR22938.1 - 0.0019 17.4 0.0 0.0058 15.8 0.0 1.8 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 CAR22938.1 - 0.0066 16.5 0.0 0.027 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CAR22938.1 - 0.0088 15.1 0.0 0.026 13.6 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_23 PF13476.1 CAR22938.1 - 0.013 15.8 0.0 0.013 15.8 0.0 3.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CAR22938.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain VGLL4 PF15245.1 CAR22938.1 - 0.043 13.6 0.3 0.13 12.0 0.2 1.8 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Zot PF05707.7 CAR22938.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.13 CAR22938.1 - 0.072 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 CAR22938.1 - 0.078 12.9 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 CAR22938.1 - 0.082 12.5 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain UBA PF00627.26 CAR22938.1 - 0.13 12.1 0.1 0.58 10.0 0.1 2.1 2 0 0 2 2 2 0 UBA/TS-N domain CDC73 PF05179.9 CAR22939.1 - 3.3e-64 216.8 0.0 4.8e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family MFS_1 PF07690.11 CAR22940.1 - 1.9e-27 95.9 21.0 2.8e-27 95.3 14.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily EF-hand_1 PF00036.27 CAR22941.1 - 4e-24 82.0 11.7 1.8e-05 23.6 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CAR22941.1 - 1.3e-20 73.2 4.0 3e-11 43.2 1.6 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR22941.1 - 5.4e-20 69.4 4.4 0.00013 21.5 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CAR22941.1 - 9.6e-15 53.1 16.9 0.00079 18.6 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CAR22941.1 - 2.3e-11 43.1 16.3 0.0018 17.8 0.3 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CAR22941.1 - 4.9e-06 26.2 10.0 0.038 13.7 0.3 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAR22941.1 - 1e-05 25.5 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CAR22941.1 - 0.00067 19.5 0.0 0.52 10.2 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain Diphthamide_syn PF01866.12 CAR22942.1 - 2.8e-39 135.2 0.0 1.6e-20 73.5 0.0 2.2 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Amidohydro_4 PF13147.1 CAR22943.1 - 4.1e-10 40.1 0.0 5.4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 CAR22943.1 - 1.9e-07 30.9 0.0 3.4e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Proteasom_Rpn13 PF04683.8 CAR22945.1 - 9.6e-22 76.8 0.0 1.4e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor YebG PF07130.7 CAR22945.1 - 0.16 11.7 1.5 0.26 10.9 1.1 1.4 1 0 0 1 1 1 0 YebG protein CinA PF02464.12 CAR22946.1 - 1.5e-29 102.4 0.0 1.8e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Competence-damaged protein Ded_cyto PF06920.8 CAR22947.1 - 2.6e-24 85.4 0.0 6.2e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_6 PF12913.2 CAR22947.1 - 0.05 12.8 0.1 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type PP-binding PF00550.20 CAR22948.1 - 2.6e-13 49.9 0.3 3.5e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CAR22948.1 - 1.5e-06 28.1 0.5 2.2e-06 27.6 0.3 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 CAR22948.1 - 0.0003 20.8 0.3 0.00044 20.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) LRR_4 PF12799.2 CAR22949.1 - 1.3e-45 152.3 37.9 5.4e-11 41.8 2.5 7.1 3 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR22949.1 - 1.3e-26 92.0 41.6 3.3e-09 36.3 2.8 6.1 3 1 4 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 CAR22949.1 - 1.5e-14 51.7 35.5 0.12 12.5 0.2 11.3 9 2 2 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 CAR22949.1 - 3e-13 48.3 28.3 0.039 14.0 0.6 10.6 6 2 4 10 10 10 5 Leucine Rich repeat LRR_7 PF13504.1 CAR22949.1 - 4.3e-12 44.1 14.9 0.63 10.4 0.0 9.7 10 1 0 10 10 10 3 Leucine rich repeat LRR_9 PF14580.1 CAR22949.1 - 1.8e-10 40.6 13.7 4.2e-07 29.7 1.5 3.3 1 1 2 3 3 3 2 Leucine-rich repeat LRR_5 PF13306.1 CAR22949.1 - 0.0069 16.0 0.5 0.0069 16.0 0.3 2.6 1 1 1 2 2 2 1 Leucine rich repeats (6 copies) DUF3744 PF12558.3 CAR22949.1 - 0.033 14.6 11.2 0.15 12.4 0.7 4.2 1 1 2 4 4 4 0 ATP-binding cassette cobalt transporter tRNA-synt_2b PF00587.20 CAR22950.1 - 1.2e-47 161.6 0.1 3.3e-47 160.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR22950.1 - 2.7e-19 68.8 0.0 4.5e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.7 CAR22951.1 - 6e-93 311.8 22.6 6.8e-93 311.7 15.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 AcylCoA_dehyd_C PF12186.3 CAR22951.1 - 0.015 15.1 3.6 0.075 12.8 0.0 3.5 2 1 2 4 4 4 0 Acyl-CoA dehydrogenase C terminal DUF2435 PF10363.4 CAR22951.1 - 0.042 13.7 2.9 0.21 11.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Tup_N PF08581.5 CAR22951.1 - 0.054 13.6 0.7 0.054 13.6 0.5 3.0 2 1 1 3 3 3 0 Tup N-terminal Baculo_PEP_C PF04513.7 CAR22951.1 - 0.064 13.0 15.0 0.16 11.8 0.1 4.3 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 CAR22951.1 - 0.21 9.9 2.1 1.2 7.4 0.4 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family WXG100 PF06013.7 CAR22951.1 - 0.42 10.6 12.5 4.1 7.4 0.2 4.5 5 0 0 5 5 5 0 Proteins of 100 residues with WXG Tropomyosin_1 PF12718.2 CAR22951.1 - 2.6 7.8 20.9 0.021 14.6 2.3 3.9 3 1 1 4 4 4 0 Tropomyosin like FTO_CTD PF12934.2 CAR22951.1 - 4.3 6.8 10.0 0.46 10.0 0.3 3.1 2 2 1 3 3 3 0 FTO C-terminal domain DUF2458 PF10454.4 CAR22951.1 - 5.3 6.9 17.8 0.051 13.4 0.6 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF2458) DUF948 PF06103.6 CAR22951.1 - 5.3 6.9 13.8 2.1 8.2 0.2 4.5 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) G-patch PF01585.18 CAR22952.1 - 7.7e-14 51.2 0.5 1.6e-13 50.1 0.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CAR22952.1 - 3.7e-07 29.8 0.0 6.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site GCFC PF07842.7 CAR22952.1 - 9.7e-06 25.1 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Gp-FAR-1 PF05823.7 CAR22952.1 - 0.065 13.2 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CHCH PF06747.8 CAR22953.1 - 6.2e-08 32.3 3.3 1.4e-07 31.2 2.3 1.7 1 0 0 1 1 1 1 CHCH domain Synaptobrevin PF00957.16 CAR22954.1 - 4.3e-15 55.0 0.7 6.7e-15 54.4 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CAR22954.1 - 7.4e-14 51.0 0.0 1.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CNH PF00780.17 CAR22955.1 - 8.3e-15 54.9 1.5 1.9e-14 53.7 0.8 1.8 2 0 0 2 2 2 1 CNH domain PH PF00169.24 CAR22955.1 - 4.4e-11 42.8 3.7 5.8e-11 42.5 1.1 2.4 2 0 0 2 2 2 1 PH domain PH_5 PF15405.1 CAR22955.1 - 1.8e-07 31.2 3.3 9.6e-07 28.8 2.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 CAR22955.1 - 4.1e-07 30.0 0.0 1.2e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_11 PF15413.1 CAR22955.1 - 0.058 13.6 1.1 0.29 11.4 0.1 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain adh_short PF00106.20 CAR22956.1 - 8.5e-24 84.3 0.0 4.9e-23 81.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR22956.1 - 1.2e-12 48.1 0.0 1.5e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR22956.1 - 1.2e-08 34.8 0.1 4e-07 29.8 0.0 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 CAR22956.1 - 0.00051 19.5 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAR22956.1 - 0.062 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 CAR22956.1 - 0.062 11.9 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Dak1_2 PF13684.1 CAR22956.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family SPC25 PF06703.6 CAR22957.1 - 2.9e-41 140.7 4.1 3.2e-41 140.5 2.8 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-C3HC4 PF00097.20 CAR22958.1 - 4.2e-07 29.5 4.3 1.2e-06 28.0 3.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR22958.1 - 5.6e-07 29.2 4.4 9.6e-07 28.5 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR22958.1 - 8.7e-07 28.5 4.7 2e-06 27.4 3.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR22958.1 - 2.6e-06 27.3 4.7 7.4e-06 25.8 3.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR22958.1 - 4.6e-06 26.2 4.0 8.7e-06 25.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAR22958.1 - 0.0001 21.9 2.0 0.00022 20.8 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAR22958.1 - 0.00062 19.5 3.3 0.00062 19.5 2.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF1900 PF08954.6 CAR22959.1 - 1.5e-45 154.0 0.0 9.7e-45 151.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CAR22959.1 - 7.4e-34 115.2 0.2 1.3e-33 114.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CAR22959.1 - 4.5e-28 96.0 5.6 2.1e-08 33.7 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 CAR22959.1 - 5.6e-09 34.6 0.2 7.8e-05 20.9 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CAR22959.1 - 0.0038 16.9 0.0 0.048 13.3 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SEN1_N PF12726.2 CAR22960.1 - 3.3e-225 749.4 25.5 4.2e-225 749.1 17.7 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 CAR22960.1 - 8.7e-69 231.6 0.2 8.7e-69 231.6 0.2 2.4 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 CAR22960.1 - 6.4e-63 211.7 0.0 1.5e-62 210.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CAR22960.1 - 1.8e-10 40.4 0.0 5.7e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CAR22960.1 - 1.2e-07 31.4 0.0 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CAR22960.1 - 1.3e-05 24.8 0.0 0.03 13.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CAR22960.1 - 0.0019 18.3 0.0 0.057 13.5 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Arteri_nucleo PF01481.11 CAR22961.1 - 0.12 12.4 0.5 0.26 11.3 0.4 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein SYCE1 PF15233.1 CAR22961.1 - 0.14 12.0 4.8 0.85 9.5 0.8 3.1 3 0 0 3 3 3 0 Synaptonemal complex central element protein 1 Syntaxin PF00804.20 CAR22961.1 - 0.34 11.0 4.3 0.8 9.9 0.0 2.8 3 0 0 3 3 3 0 Syntaxin DivIC PF04977.10 CAR22961.1 - 0.9 9.0 4.7 5.1 6.6 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator IMPDH PF00478.20 CAR22962.1 - 5.7e-144 479.3 3.5 6.9e-144 479.0 2.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CAR22962.1 - 1.2e-14 53.8 0.1 1e-07 31.5 0.0 2.8 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.13 CAR22962.1 - 1.8e-08 33.6 2.5 2.9e-08 32.9 0.9 1.9 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CAR22962.1 - 2.1e-07 30.4 8.4 0.00014 21.1 2.9 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 CAR22962.1 - 0.00046 19.5 1.1 0.0037 16.5 0.1 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 CAR22962.1 - 0.0013 17.8 1.2 0.0028 16.7 0.4 1.7 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 CAR22962.1 - 0.0074 15.4 0.1 0.025 13.7 0.0 1.9 1 0 0 1 1 1 1 KDPG and KHG aldolase FIST PF08495.5 CAR22962.1 - 0.042 13.0 0.1 0.083 12.0 0.1 1.5 1 0 0 1 1 1 0 FIST N domain Metallophos PF00149.23 CAR22963.1 - 3e-43 147.5 0.1 4.6e-43 146.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WGG PF10273.4 CAR22964.1 - 6e-31 106.3 0.3 1.3e-30 105.2 0.2 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 CAR22964.1 - 0.22 11.5 2.0 0.22 11.5 0.6 1.7 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) RNA_pol_3_Rpc31 PF11705.3 CAR22964.1 - 0.61 9.9 7.5 0.8 9.5 5.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Hid1 PF12722.2 CAR22965.1 - 1.7e-287 955.8 21.1 2e-287 955.6 14.6 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein RNR_inhib PF08591.5 CAR22966.1 - 8.5e-17 61.8 0.2 1.1e-16 61.5 0.1 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.16 CAR22967.1 - 3.3e-105 351.6 0.0 4e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CAR22967.1 - 0.00036 19.7 0.0 0.00076 18.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CAR22967.1 - 0.025 13.5 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II cNMP_binding PF00027.24 CAR22968.1 - 2.6e-35 120.0 0.0 9.7e-16 57.3 0.0 4.5 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 CAR22968.1 - 7.7e-20 71.6 3.1 1.3e-18 67.6 2.1 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase LSM PF01423.17 CAR22969.1 - 4.5e-17 61.3 0.1 5.7e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF2272 PF10030.4 CAR22969.1 - 0.056 12.9 0.0 0.061 12.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) MRP-L47 PF06984.8 CAR22970.1 - 1.4e-25 89.0 1.8 2.1e-25 88.4 0.5 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2884 PF11101.3 CAR22970.1 - 0.017 14.4 0.4 0.017 14.4 0.3 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2884) OGG_N PF07934.7 CAR22971.1 - 1.7e-22 79.5 0.5 3.6e-22 78.5 0.1 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CAR22971.1 - 1.3e-14 54.4 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Glucodextran_N PF09137.6 CAR22971.1 - 0.054 12.7 0.1 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucodextranase, domain N PIF1 PF05970.9 CAR22972.1 - 1.1e-66 225.3 1.1 4.4e-49 167.3 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CAR22972.1 - 1.9e-12 47.1 0.0 5.9e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CAR22972.1 - 5.5e-05 21.1 0.3 0.003 15.3 0.0 2.4 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.1 CAR22972.1 - 6.9e-05 22.9 0.1 0.00028 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR22972.1 - 0.00017 21.2 0.2 0.00052 19.7 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 CAR22972.1 - 0.00043 19.2 0.3 0.0012 17.8 0.1 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CAR22972.1 - 0.00076 19.5 0.0 0.0083 16.2 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 CAR22972.1 - 0.016 14.4 0.0 0.046 12.9 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein DUF2950 PF11453.3 CAR22972.1 - 0.025 13.5 0.1 0.049 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) FtsK_SpoIIIE PF01580.13 CAR22972.1 - 0.031 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sec39 PF08314.6 CAR22973.1 - 6.8e-111 371.4 2.7 7.9e-111 371.2 1.9 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 THOC7 PF05615.8 CAR22974.1 - 9.2e-10 38.9 18.3 1.5e-09 38.2 7.5 2.3 2 0 0 2 2 2 1 Tho complex subunit 7 bZIP_1 PF00170.16 CAR22974.1 - 0.051 13.5 0.4 0.051 13.5 0.3 3.8 2 1 2 4 4 4 0 bZIP transcription factor DASH_Duo1 PF08651.5 CAR22974.1 - 0.12 11.9 4.6 0.11 12.0 0.9 2.6 2 1 1 3 3 3 0 DASH complex subunit Duo1 Laminin_II PF06009.7 CAR22974.1 - 0.31 10.7 11.4 0.32 10.7 3.0 2.6 2 0 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.4 CAR22974.1 - 0.55 10.4 10.4 1.8 8.7 3.7 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 CAR22974.1 - 4.7 6.7 12.5 3 7.3 1.3 3.5 2 1 1 3 3 3 0 Septum formation initiator DUF4611 PF15387.1 CAR22974.1 - 8.1 6.6 19.5 1.1 9.4 6.9 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4611) DUF2175 PF09943.4 CAR22974.1 - 8.4 6.5 11.9 0.34 10.9 1.2 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Ribosomal_S3Ae PF01015.13 CAR22975.1 - 1.6e-80 269.0 5.7 1.8e-80 268.8 4.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 CAR22975.1 - 0.11 11.9 0.0 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ras PF00071.17 CAR22976.1 - 2.4e-31 108.3 0.0 2.8e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR22976.1 - 2.7e-19 69.8 0.1 1.9e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR22976.1 - 1.6e-05 24.1 0.0 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR22976.1 - 6.3e-05 22.4 0.0 0.00052 19.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR22976.1 - 0.00013 21.2 0.1 0.00015 20.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR22976.1 - 0.0012 18.1 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CAR22976.1 - 0.0039 17.1 0.0 0.0072 16.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CAR22976.1 - 0.045 12.4 0.0 0.074 11.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.4 CAR22976.1 - 0.082 12.3 0.1 0.36 10.3 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CAR22977.1 - 3.8e-17 62.7 0.0 8.7e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 CAR22977.1 - 4.2e-10 39.3 0.0 3.1e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 BAH domain AAA_16 PF13191.1 CAR22977.1 - 1.9e-08 34.5 0.0 9.8e-07 28.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAR22977.1 - 1.4e-06 28.5 0.1 1.1e-05 25.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CAR22977.1 - 3.9e-06 26.7 0.5 0.00013 21.7 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 CAR22977.1 - 0.00017 21.2 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2666 PF10869.3 CAR22977.1 - 0.0075 16.3 0.5 0.15 12.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2666) AAA_17 PF13207.1 CAR22977.1 - 0.0086 16.8 0.0 0.033 15.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR22977.1 - 0.011 16.0 0.1 0.057 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CAR22977.1 - 0.032 13.9 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 CAR22977.1 - 0.056 13.6 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SUR7 PF06687.7 CAR22978.1 - 7.4e-08 32.2 9.9 7.4e-08 32.2 6.9 1.5 2 0 0 2 2 2 1 SUR7/PalI family PIG-P PF08510.7 CAR22978.1 - 0.24 11.0 3.2 0.47 10.1 1.1 2.1 1 1 1 2 2 2 0 PIG-P DUF3488 PF11992.3 CAR22979.1 - 3.4 6.1 10.6 0.064 11.8 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) COPIIcoated_ERV PF07970.7 CAR22980.1 - 1.6e-29 103.1 0.0 2.3e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CAR22980.1 - 7.7e-19 67.4 0.0 7.7e-19 67.4 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) INSIG PF07281.7 CAR22980.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Ribosomal_L11 PF00298.14 CAR22981.1 - 0.14 12.3 0.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain IBR PF01485.16 CAR22982.1 - 3.5e-14 52.4 18.7 1.2e-08 34.7 2.3 4.2 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 CAR22982.1 - 2.2e-05 24.1 8.3 2.2e-05 24.1 5.8 4.0 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4_3 PF13920.1 CAR22982.1 - 0.00021 20.8 8.9 0.00021 20.8 6.1 4.8 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR22982.1 - 0.00025 21.0 10.5 0.00025 21.0 7.3 4.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR22982.1 - 0.0029 17.2 10.4 0.0029 17.2 7.2 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) COX17 PF05051.8 CAR22982.1 - 0.027 14.4 4.4 0.027 14.4 3.1 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) SSrecog PF03531.9 CAR22983.1 - 1.5e-72 243.5 3.4 8.5e-72 241.0 2.3 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CAR22983.1 - 6.5e-29 99.7 0.1 2.1e-25 88.4 0.0 3.2 4 0 0 4 4 4 2 Histone chaperone Rttp106-like Helicase_IV_N PF12462.3 CAR22983.1 - 0.055 13.1 0.2 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal Dak1 PF02733.12 CAR22984.1 - 7.2e-136 452.0 1.3 1e-135 451.5 0.9 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CAR22984.1 - 4.3e-44 150.2 0.3 9.9e-44 149.0 0.1 1.7 2 0 0 2 2 2 1 DAK2 domain SH3_1 PF00018.23 CAR22985.1 - 1.2e-14 53.3 0.0 2.9e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR22985.1 - 2.9e-14 52.3 0.0 6.9e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR22985.1 - 1.2e-11 43.8 0.0 2.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Phytoreo_P8 PF07124.6 CAR22985.1 - 0.011 14.4 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Zn_clus PF00172.13 CAR22986.1 - 1.2e-05 25.1 10.8 1.9e-05 24.4 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_binding_2 PF13380.1 CAR22987.1 - 1.9e-24 86.0 0.0 2.2e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Hexokinase_1 PF00349.16 CAR22988.1 - 4.3e-15 55.5 0.0 7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CAR22988.1 - 5.3e-10 38.9 0.1 2.7e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 Hexokinase PTR2 PF00854.16 CAR22989.1 - 3.7e-30 104.9 8.0 7.8e-15 54.5 0.9 2.2 2 0 0 2 2 2 2 POT family MFS_1 PF07690.11 CAR22989.1 - 0.00017 20.4 38.1 0.0068 15.1 6.3 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily B12D PF06522.6 CAR22989.1 - 0.0052 16.4 0.0 0.018 14.6 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Cyt-b5 PF00173.23 CAR22990.1 - 2.9e-11 43.0 0.0 3.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NADH_Oxid_Nqo15 PF11497.3 CAR22990.1 - 0.089 12.5 0.0 0.3 10.8 0.0 1.8 1 1 1 2 2 2 0 NADH-quinone oxidoreductase chain 15 HCV_NS4a PF01006.15 CAR22990.1 - 0.14 11.6 0.3 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a cNMP_binding PF00027.24 CAR22991.1 - 7e-37 125.1 0.0 1.9e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 CAR22991.1 - 9.9e-10 37.4 11.3 2.6 8.3 0.1 8.9 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.2 CAR22991.1 - 1.4e-08 34.1 4.9 0.19 11.3 0.0 5.3 4 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAR22991.1 - 6.1e-07 28.6 14.2 18 5.8 0.1 9.4 8 1 0 8 8 8 1 Leucine Rich Repeat F-box-like PF12937.2 CAR22991.1 - 8.3e-07 28.6 1.1 3.4e-06 26.6 0.8 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR22991.1 - 1.1e-06 28.1 2.6 5.2e-06 25.9 1.8 2.2 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 CAR22991.1 - 7.5e-06 25.6 10.4 0.012 15.3 0.4 4.8 2 1 4 6 6 6 5 Leucine rich repeat LRR_7 PF13504.1 CAR22991.1 - 0.0012 18.6 15.7 4 8.0 0.2 7.4 8 0 0 8 8 8 2 Leucine rich repeat vATP-synt_AC39 PF01992.11 CAR22992.1 - 1.6e-85 287.1 0.1 1.9e-85 287.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Dor1 PF04124.7 CAR22993.1 - 2.7e-22 78.6 2.2 7.5e-22 77.2 1.5 1.6 1 1 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 CAR22993.1 - 0.00043 20.0 0.1 0.006 16.3 0.0 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 C2 PF00168.25 CAR22994.1 - 1.3e-51 172.4 9.6 1.1e-21 76.4 0.1 5.6 6 0 0 6 6 6 4 C2 domain Ribosomal_L6e PF01159.14 CAR22996.1 - 6.9e-39 132.4 0.4 8.9e-39 132.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e FKBP_C PF00254.23 CAR22997.1 - 6.5e-28 96.5 0.0 2.5e-27 94.7 0.0 2.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Draxin PF15550.1 CAR22997.1 - 0.053 13.1 17.4 0.029 14.0 0.5 2.2 2 0 0 2 2 2 0 Draxin CAF-1_p150 PF11600.3 CAR22997.1 - 0.13 11.6 59.0 0.9 8.8 24.9 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4045 PF13254.1 CAR22997.1 - 1.1 8.4 25.2 0.44 9.7 8.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 CAR22997.1 - 1.4 8.7 13.7 5.9 6.7 0.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SET PF00856.23 CAR22997.1 - 3.8 7.7 8.5 9.7 6.4 0.3 2.4 2 0 0 2 2 2 0 SET domain GAGA_bind PF06217.7 CAR22997.1 - 4.6 7.1 25.0 1.8 8.4 1.6 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Mitofilin PF09731.4 CAR22997.1 - 8.5 4.8 37.8 3.9 6.0 15.3 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein HMG-CoA_red PF00368.13 CAR22998.1 - 1.4e-157 524.1 0.1 1.9e-157 523.6 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 CAR22998.1 - 9.1e-44 148.8 0.2 2e-43 147.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 CAR22998.1 - 1.2e-09 37.7 4.1 1.2e-09 37.7 2.8 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation TBX PF12598.3 CAR22998.1 - 0.11 12.9 2.9 0.22 11.9 2.0 1.4 1 0 0 1 1 1 0 T-box transcription factor Patched PF02460.13 CAR22998.1 - 0.34 8.7 12.1 0.089 10.6 6.0 1.6 2 0 0 2 2 2 0 Patched family Zn_clus PF00172.13 CAR23001.1 - 0.00054 19.8 11.8 0.00093 19.0 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_c3_2 PF14537.1 CAR23001.1 - 0.0062 16.8 3.5 0.012 15.9 2.4 1.4 1 0 0 1 1 1 1 Cytochrome c3 Cytochrome_C7 PF14522.1 CAR23001.1 - 0.021 14.4 3.5 0.042 13.4 2.4 1.4 1 0 0 1 1 1 0 Cytochrome c7 Cytochrom_C PF00034.16 CAR23001.1 - 1.1 10.1 3.9 45 4.9 2.6 2.5 1 1 0 1 1 1 0 Cytochrome c Sybindin PF04099.7 CAR23002.1 - 4.8e-19 68.4 0.0 6.1e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family ENTH PF01417.15 CAR23003.1 - 2.9e-44 149.9 0.1 4.4e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CAR23003.1 - 0.00083 18.1 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 ANTH domain Bd3614_N PF14442.1 CAR23003.1 - 1.9 8.4 11.1 6 6.8 1.8 2.5 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Pro_isomerase PF00160.16 CAR23004.1 - 1.6e-45 155.0 0.2 1.8e-45 154.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MARVEL PF01284.18 CAR23005.1 - 7.2e-10 38.8 16.5 1e-09 38.3 11.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.11 CAR23006.1 - 7.2e-32 110.4 51.1 1.2e-25 89.9 14.6 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 CAR23006.1 - 8.2e-09 34.2 16.1 5.2e-06 24.9 4.0 3.1 3 0 0 3 3 3 3 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 CAR23006.1 - 4.5 7.3 10.8 0.12 12.4 0.6 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) HRXXH PF13933.1 CAR23007.1 - 2.6e-84 282.5 0.0 3e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 CAR23007.1 - 0.066 13.7 0.1 1 9.8 0.1 2.3 1 1 0 1 1 1 0 Lysine-specific metallo-endopeptidase Flocculin PF00624.13 CAR23008.1 - 0 2036.6 1358.8 1.4e-15 56.8 16.4 49.6 42 7 7 49 49 49 47 Flocculin repeat PA14_2 PF10528.4 CAR23009.1 - 4.1e-21 75.0 1.4 4.1e-21 75.0 1.0 2.6 3 1 0 3 3 3 1 GLEYA domain PA14 PF07691.7 CAR23009.1 - 1e-12 47.9 1.3 1.5e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 PA14 domain Flocculin PF00624.13 CAR23009.1 - 0.00035 20.3 50.5 0.0036 17.1 15.8 4.0 4 0 0 4 4 4 2 Flocculin repeat Aminotran_4 PF01063.14 CAR23011.1 - 7.9e-31 107.3 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV 5-FTHF_cyc-lig PF01812.15 CAR23012.1 - 9.8e-38 129.7 0.0 1.1e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF2177 PF09945.4 CAR23013.1 - 0.086 12.8 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) SET PF00856.23 CAR23014.1 - 4.9e-15 56.2 0.0 1.1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 SET domain HSF_DNA-bind PF00447.12 CAR23015.1 - 1.3e-36 124.9 7.9 3.9e-36 123.3 5.5 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 CAR23015.1 - 2.5e-26 91.9 0.6 6.6e-26 90.5 0.2 1.9 2 0 0 2 2 2 1 Response regulator receiver domain DUF904 PF06005.7 CAR23015.1 - 0.098 12.9 1.7 0.27 11.5 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 CAR23015.1 - 0.14 11.9 2.0 0.35 10.6 1.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper RuBisCO_small PF00101.15 CAR23015.1 - 0.18 11.6 1.3 5.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain Pkinase PF00069.20 CAR23016.1 - 2.3e-68 230.1 0.0 3.7e-68 229.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23016.1 - 1.4e-30 106.2 0.0 2.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CAR23016.1 - 8.6e-12 45.4 2.5 3.3e-11 43.5 1.7 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR23016.1 - 2.8e-09 36.3 0.0 6.2e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 CAR23016.1 - 3.6e-06 26.7 0.0 3.7e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 C2 domain YrbL-PhoP_reg PF10707.4 CAR23016.1 - 0.028 13.7 0.0 0.075 12.3 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CAR23016.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.15 CAR23017.1 - 3.3e-130 434.7 0.1 7.4e-130 433.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Ribosomal_S4e PF00900.15 CAR23018.1 - 2.7e-32 110.2 0.9 5.5e-32 109.2 0.4 1.6 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CAR23018.1 - 2.7e-20 71.9 5.4 5.4e-20 70.9 3.7 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CAR23018.1 - 2.9e-08 33.0 0.0 6.2e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CAR23018.1 - 0.00011 21.7 1.4 0.00011 21.7 1.0 3.4 4 0 0 4 4 4 1 KOW motif Metallophos PF00149.23 CAR23019.1 - 1.3e-07 31.1 5.1 3.5e-07 29.8 3.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Mgm101p PF06420.7 CAR23020.1 - 2e-89 297.4 0.0 2.4e-89 297.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PMT PF02366.13 CAR23021.1 - 7e-74 248.2 20.9 1.5e-73 247.1 14.5 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CAR23021.1 - 1e-25 90.3 1.1 2.1e-25 89.3 0.5 1.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 CAR23021.1 - 6.7e-06 26.0 15.6 6.7e-06 26.0 10.8 2.9 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase NUDIX PF00293.23 CAR23022.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DHHA2 PF02833.9 CAR23023.1 - 1.1e-23 83.8 0.1 1.8e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CAR23023.1 - 6.6e-09 35.5 0.1 1.5e-08 34.3 0.1 1.5 1 1 0 1 1 1 1 DHH family HECT_2 PF09814.4 CAR23024.1 - 4e-70 236.3 0.6 4.5e-70 236.1 0.4 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Homoserine_dh PF00742.14 CAR23026.1 - 2.3e-52 177.2 0.0 3.2e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CAR23026.1 - 3.1e-16 59.8 0.0 5.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3608 PF12257.3 CAR23027.1 - 1.4e-132 440.7 1.2 2.5e-132 440.0 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CAR23027.1 - 1.9e-26 91.5 0.6 4.8e-26 90.2 0.4 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) VWA_2 PF13519.1 CAR23028.1 - 2.2e-11 44.1 0.0 3.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 CAR23028.1 - 7.1e-10 38.7 0.0 9.2e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 CAR23028.1 - 0.00011 21.9 0.5 0.00016 21.4 0.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 CAR23028.1 - 0.0015 17.9 1.3 0.0038 16.6 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif NIR_SIR PF01077.17 CAR23029.1 - 5.2e-50 168.8 0.0 6.7e-46 155.5 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CAR23029.1 - 4.6e-28 96.6 0.1 6.2e-13 48.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CAR23029.1 - 6.6e-28 97.5 0.0 1.3e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Chalcone PF02431.10 CAR23030.1 - 1e-53 181.7 0.0 1.6e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Indigoidine_A PF04227.7 CAR23031.1 - 8.5e-120 399.4 0.2 1.1e-119 399.0 0.1 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 CAR23031.1 - 2.6e-09 36.6 0.0 3.7e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF2454 PF10521.4 CAR23032.1 - 2.4e-54 184.2 0.2 3.6e-54 183.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) zf-Tim10_DDP PF02953.10 CAR23033.1 - 7.1e-21 73.2 4.6 9.3e-21 72.8 3.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger EF-hand_like PF09279.6 CAR23033.1 - 0.026 14.5 0.7 0.036 14.0 0.4 1.3 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF842 PF05811.8 CAR23033.1 - 0.037 13.4 3.8 0.056 12.9 2.5 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tho2 PF11262.3 CAR23034.1 - 0.056 12.4 0.4 2.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 RIX1 PF08167.7 CAR23035.1 - 5e-45 153.1 5.6 5e-45 153.1 3.9 2.1 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis TMF_TATA_bd PF12325.3 CAR23036.1 - 1.1e-34 118.7 19.2 1.1e-34 118.7 13.3 5.3 3 2 0 4 4 4 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CAR23036.1 - 2e-15 56.3 18.4 2e-15 56.3 12.8 8.8 5 3 5 10 10 10 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 CAR23036.1 - 0.00011 22.0 84.4 0.22 11.3 3.0 6.6 3 2 3 6 6 6 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 CAR23036.1 - 0.021 13.9 70.9 0.055 12.6 20.0 3.8 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1493 PF07377.7 CAR23036.1 - 0.28 11.3 4.6 1.7 8.7 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1493) ATG16 PF08614.6 CAR23036.1 - 3.9 7.2 74.5 0.28 11.0 5.2 4.4 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Pribosyltran PF00156.22 CAR23037.1 - 7.1e-14 51.6 0.4 6.9e-13 48.4 0.2 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Ribosomal_S25 PF03297.10 CAR23038.1 - 0.02 14.9 0.1 0.049 13.6 0.1 1.6 1 0 0 1 1 1 0 S25 ribosomal protein IBN_N PF03810.14 CAR23039.1 - 7.2e-12 45.0 0.0 8.2e-11 41.6 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain MDM31_MDM32 PF08118.6 CAR23041.1 - 3.6e-274 909.8 3.4 4.2e-274 909.5 2.3 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins NAC PF01849.13 CAR23042.1 - 1.5e-19 69.2 0.2 6.9e-19 67.1 0.1 2.0 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CAR23042.1 - 0.001 18.8 0.2 0.0027 17.4 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF2296 PF10058.4 CAR23043.1 - 6.5e-14 51.4 0.2 1.4e-13 50.3 0.2 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) OmpH PF03938.9 CAR23043.1 - 0.0083 16.0 1.6 0.0083 16.0 1.1 1.7 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) V-SNARE PF05008.10 CAR23043.1 - 0.014 15.5 7.2 0.057 13.5 2.8 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Cys_rich_CPCC PF14206.1 CAR23043.1 - 0.032 13.7 0.3 0.063 12.8 0.2 1.4 1 0 0 1 1 1 0 Cysteine-rich CPCC zf-H2C2_2 PF13465.1 CAR23043.1 - 0.04 14.2 0.7 8.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain NicO PF03824.11 CAR23043.1 - 0.047 13.0 0.2 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein zf-C2H2 PF00096.21 CAR23043.1 - 0.11 12.9 3.2 1.3 9.5 0.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rubredoxin PF00301.15 CAR23043.1 - 0.13 12.1 0.3 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 Rubredoxin A2L_zn_ribbon PF08792.5 CAR23043.1 - 0.24 10.8 3.9 3 7.4 2.7 2.3 1 1 0 1 1 1 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 CAR23043.1 - 0.26 10.5 2.3 7.4 5.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF4200 PF13863.1 CAR23043.1 - 0.39 10.6 13.7 1.4 8.9 6.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF883 PF05957.8 CAR23043.1 - 0.41 11.0 2.2 0.78 10.1 0.5 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TF_Zn_Ribbon PF08271.7 CAR23043.1 - 0.48 9.7 2.1 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding FliJ PF02050.11 CAR23043.1 - 0.48 10.4 16.6 0.66 10.0 7.8 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein FliD_N PF02465.13 CAR23043.1 - 0.94 9.8 6.6 3.8 7.9 0.1 3.2 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus RRF_GI PF12614.3 CAR23043.1 - 2.1 8.1 5.6 1.9 8.3 0.2 2.7 2 1 1 3 3 3 0 Ribosome recycling factor UPF0547 PF10571.4 CAR23043.1 - 4.1 7.1 6.6 2.1 8.1 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 TMF_DNA_bd PF12329.3 CAR23043.1 - 4.8 7.0 11.7 5.7 6.8 1.1 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 CAR23043.1 - 6.3 6.5 10.6 3.2 7.5 2.0 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ctf8 PF09696.5 CAR23044.1 - 4.1e-28 97.6 0.1 5.7e-28 97.1 0.1 1.2 1 0 0 1 1 1 1 Ctf8 Glyco_hydro_47 PF01532.15 CAR23045.1 - 4.9e-146 486.9 1.4 5.7e-146 486.7 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cys_Met_Meta_PP PF01053.15 CAR23046.1 - 4.1e-27 94.4 0.0 4.2e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CAR23046.1 - 0.0038 16.2 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PDE6_gamma PF04868.7 CAR23046.1 - 0.019 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit ATP-synt_J PF04911.7 CAR23047.1 - 1.8e-27 94.5 0.8 2e-27 94.3 0.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain DUF3185 PF11381.3 CAR23047.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Allantoicase PF03561.10 CAR23048.1 - 8.6e-103 340.2 0.3 1.5e-55 186.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Methyltransf_16 PF10294.4 CAR23049.1 - 3.1e-20 72.3 0.0 5.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CAR23049.1 - 4.6e-06 27.1 0.0 2.2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CAR23049.1 - 0.00048 19.5 0.0 0.0011 18.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 CAR23049.1 - 0.0017 17.5 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CAR23049.1 - 0.0018 17.8 0.0 0.0096 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR23049.1 - 0.011 16.1 0.0 0.086 13.3 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 CAR23049.1 - 0.017 15.4 0.0 0.063 13.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 CAR23049.1 - 0.028 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2 PF00096.21 CAR23052.1 - 8.1e-07 29.0 15.5 0.00027 21.1 1.2 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR23052.1 - 2e-06 27.7 7.9 4.5e-05 23.5 2.9 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR23052.1 - 4.6e-05 23.4 13.9 0.0017 18.5 1.5 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger Dus PF01207.12 CAR23053.1 - 6.9e-79 264.8 0.0 8.9e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Cupin_5 PF06172.6 CAR23054.1 - 6.9e-30 103.7 0.0 1.3e-29 102.8 0.0 1.4 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Peptidase_M28 PF04389.12 CAR23055.1 - 8.5e-16 58.1 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CAR23055.1 - 4.3e-11 42.4 0.0 9.3e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M20 PF01546.23 CAR23055.1 - 3.3e-05 23.4 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.17 CAR23055.1 - 5.9e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 PA domain MFS_1 PF07690.11 CAR23056.1 - 1.7e-06 27.0 48.2 8.4e-05 21.4 33.4 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR23056.1 - 0.00077 18.1 10.8 0.00077 18.1 7.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Flocculin PF00624.13 CAR23057.1 - 1.9e-52 174.8 140.4 8.2e-16 57.5 20.5 12.5 10 2 1 11 11 11 4 Flocculin repeat PA14_2 PF10528.4 CAR23057.1 - 4.9e-17 61.9 0.1 1.9e-16 60.0 0.1 2.1 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 CAR23057.1 - 2.6e-08 33.6 0.0 1.6e-07 31.0 0.0 2.5 1 0 0 1 1 1 1 PA14 domain Med3 PF11593.3 CAR23057.1 - 1.3 8.2 0.0 1.3 8.2 0.0 11.3 1 1 9 10 10 10 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 CAR23058.1 - 2.6e-29 102.0 23.4 2.6e-29 102.0 16.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 CAR23058.1 - 5.9 5.3 8.7 0.25 9.8 1.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) IU_nuc_hydro PF01156.14 CAR23059.1 - 2.1e-46 158.6 0.3 2.6e-46 158.2 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ATP-synt_DE_N PF02823.11 CAR23059.1 - 0.055 13.2 0.0 8 6.2 0.0 3.1 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Transketolase_C PF02780.15 CAR23059.1 - 0.11 12.4 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fungal_trans_2 PF11951.3 CAR23060.1 - 6.9e-44 149.9 0.0 8.4e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR23060.1 - 0.0001 22.1 12.8 0.00021 21.1 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3733 PF12534.3 CAR23060.1 - 0.25 10.6 1.5 0.37 10.1 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 ApbA_C PF08546.6 CAR23061.1 - 2.1e-31 108.5 0.0 4.1e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CAR23061.1 - 2e-25 88.9 0.0 2.9e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.16 CAR23062.1 - 3e-51 173.9 0.0 3.7e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flocculin PF00624.13 CAR23063.1 - 3.3e-90 295.7 238.0 2.5e-16 59.2 19.4 14.9 14 3 2 16 16 16 7 Flocculin repeat PA14_2 PF10528.4 CAR23063.1 - 1.4e-11 44.3 0.0 1.1e-10 41.4 0.0 2.7 1 1 0 1 1 1 1 GLEYA domain PHO4 PF01384.15 CAR23064.1 - 7.3e-114 379.7 14.3 1e-113 379.3 9.9 1.2 1 0 0 1 1 1 1 Phosphate transporter family Ferritin_2 PF13668.1 CAR23065.1 - 7.7e-40 136.0 0.6 1.1e-39 135.5 0.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain DIOX_N PF14226.1 CAR23066.1 - 3.5e-26 92.0 0.1 1.2e-25 90.2 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CAR23066.1 - 2.6e-13 50.1 0.0 4.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CN_hydrolase PF00795.17 CAR23067.1 - 1.9e-33 115.3 0.0 2.5e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 CAR23068.1 - 1.7e-36 125.4 1.5 2.6e-36 124.8 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.16 CAR23069.1 - 2.2e-90 302.9 0.0 2.6e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1445 PF07286.7 CAR23070.1 - 6.1e-29 100.5 0.0 8.3e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Fungal_trans PF04082.13 CAR23071.1 - 3.1e-14 52.4 3.6 8.2e-14 51.0 2.5 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR23071.1 - 0.00069 19.4 12.9 0.0013 18.5 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CAR23072.1 - 4.9e-41 140.6 25.0 6.3e-41 140.2 17.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SPC25 PF06703.6 CAR23072.1 - 1.2 8.7 4.5 26 4.3 0.7 2.9 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Hydantoinase_B PF02538.9 CAR23073.1 - 4.4e-217 721.4 0.0 5.8e-217 721.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CAR23073.1 - 1.8e-91 306.2 0.1 3.5e-91 305.3 0.1 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CAR23073.1 - 9.5e-51 171.7 0.1 5.6e-49 166.0 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 CAR23074.1 - 2.2e-29 102.2 36.6 2.2e-29 102.2 25.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.16 CAR23075.1 - 8.8e-80 268.3 40.0 1.2e-79 267.9 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23075.1 - 6.4e-29 100.7 45.0 8.4e-29 100.3 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease AAA_26 PF13500.1 CAR23076.1 - 1.1e-42 145.9 0.0 1.3e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 CAR23076.1 - 0.00088 18.7 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_3 PF00202.16 CAR23077.1 - 2.8e-84 282.8 0.0 5.5e-84 281.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CAR23077.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Mga PF05043.8 CAR23077.1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain Metallophos PF00149.23 CAR23078.1 - 4.6e-17 62.0 4.8 1.3e-16 60.6 3.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR23078.1 - 6.7e-07 29.2 0.0 7.8e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain MFP2b PF12150.3 CAR23078.1 - 0.015 14.0 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytosolic motility protein Mitofilin PF09731.4 CAR23079.1 - 0.018 13.7 7.1 0.02 13.5 4.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Neur_chan_memb PF02932.11 CAR23079.1 - 1.8 8.4 5.7 2.5 7.9 3.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Menin PF05053.8 CAR23079.1 - 4.8 5.2 6.9 7.4 4.6 4.8 1.3 1 0 0 1 1 1 0 Menin Thiolase_N PF00108.18 CAR23080.1 - 6e-83 277.8 0.2 7.9e-83 277.4 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CAR23080.1 - 6.2e-46 154.8 0.8 1.4e-45 153.7 0.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CAR23080.1 - 0.011 15.2 0.3 0.054 12.9 0.1 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CAR23080.1 - 0.36 10.5 4.0 0.63 9.7 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FH2 PF02181.18 CAR23081.1 - 5e-62 209.9 4.0 5e-62 209.9 2.8 3.1 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CAR23081.1 - 2.1e-14 53.3 0.0 2.1e-14 53.3 0.0 3.7 3 1 1 4 4 4 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CAR23081.1 - 0.00093 18.6 5.0 0.00093 18.6 3.5 4.1 2 1 0 3 3 3 2 Diaphanous FH3 Domain SKG6 PF08693.5 CAR23082.1 - 8e-05 21.8 0.9 8e-05 21.8 0.7 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF737 PF05300.6 CAR23082.1 - 0.59 10.0 7.6 0.042 13.8 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Coa1 PF08695.5 CAR23083.1 - 1.1e-38 131.3 0.0 1.3e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1748 PF08520.5 CAR23084.1 - 3.5e-32 109.8 0.0 3.8e-32 109.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Myb_DNA-binding PF00249.26 CAR23085.1 - 1.7e-24 85.6 8.8 1.7e-10 40.8 0.3 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR23085.1 - 1.7e-23 82.4 6.8 4.6e-10 39.4 0.4 4.5 3 1 1 4 4 4 3 Myb-like DNA-binding domain Dicty_REP PF05086.7 CAR23085.1 - 3.6 5.2 12.0 5.9 4.5 8.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tyrosinase PF00264.15 CAR23085.1 - 5.7 7.0 17.1 17 5.4 11.3 2.1 1 1 0 1 1 1 0 Common central domain of tyrosinase UCH PF00443.24 CAR23086.1 - 4.8e-58 196.4 5.5 9.8e-58 195.3 3.8 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR23086.1 - 4.3e-28 98.6 4.9 8.5e-28 97.6 3.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CAR23086.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zinc_ribbon_2 PF13240.1 CAR23086.1 - 0.19 11.2 2.7 12 5.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DAO PF01266.19 CAR23087.1 - 3.9e-51 174.0 0.0 5e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR23087.1 - 1.1e-11 44.2 3.9 5e-11 42.0 2.7 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CAR23087.1 - 1.5e-09 37.4 5.1 6.6e-08 32.0 4.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAR23087.1 - 2.5e-05 24.2 0.1 0.0046 16.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CAR23087.1 - 0.0005 19.0 0.4 0.0078 15.1 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 CAR23087.1 - 0.0037 15.8 0.7 0.0059 15.1 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 CAR23087.1 - 0.0037 16.3 0.4 1.7 7.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain GMC_oxred_N PF00732.14 CAR23087.1 - 0.0048 16.0 0.6 0.0077 15.4 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.12 CAR23087.1 - 0.0081 15.2 0.1 0.16 11.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 CAR23087.1 - 0.037 14.0 2.7 0.041 13.9 0.3 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 CAR23087.1 - 0.041 13.5 2.1 0.15 11.6 1.4 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 CAR23087.1 - 0.058 12.3 0.3 0.48 9.2 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein PTPA PF03095.10 CAR23089.1 - 7.8e-111 370.0 0.0 9.6e-111 369.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PEPCK_ATP PF01293.15 CAR23090.1 - 2.7e-215 715.2 0.0 3.1e-215 715.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CAR23090.1 - 0.02 14.7 0.1 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CAR23090.1 - 0.032 13.9 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SelA PF03841.8 CAR23090.1 - 0.053 12.2 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase AAA_25 PF13481.1 CAR23090.1 - 0.092 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CAR23090.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC PIN_4 PF13638.1 CAR23093.1 - 1.3e-12 47.9 0.8 2.2e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 PIN domain S6PP PF05116.8 CAR23093.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Pcc1 PF09341.5 CAR23094.1 - 3.5e-20 71.8 0.0 3.9e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DAGK_cat PF00781.19 CAR23095.1 - 5.2e-11 42.0 0.0 1.2e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain zf-primase PF09329.6 CAR23096.1 - 5.7e-11 41.8 0.5 1.2e-10 40.7 0.4 1.6 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 CAR23096.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Viral_P18 PF04521.8 CAR23096.1 - 0.98 8.8 5.3 7 6.1 1.2 2.8 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_MLP1_2 PF07926.7 CAR23097.1 - 5.1e-27 94.2 25.8 5.1e-27 94.2 17.9 17.3 3 3 11 14 14 14 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 CAR23097.1 - 0.00097 18.4 6.8 0.00097 18.4 4.7 10.6 2 2 9 12 12 12 3 Reovirus sigma C capsid protein Col_cuticle_N PF01484.12 CAR23097.1 - 0.26 11.0 0.2 3 7.6 0.1 2.9 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain ubiquitin PF00240.18 CAR23098.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CAR23098.1 - 2.3e-30 103.9 10.5 3.7e-30 103.2 7.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CAR23098.1 - 4.4e-20 71.1 0.7 6.5e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR23098.1 - 7.3e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CAR23098.1 - 9.8e-05 22.0 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CAR23098.1 - 0.0062 16.3 0.1 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAR23098.1 - 0.012 15.8 0.1 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Response_reg PF00072.19 CAR23099.1 - 2.5e-27 95.0 0.2 4.5e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 CAR23099.1 - 7.9e-26 89.9 3.0 1.5e-24 85.8 2.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CAR23099.1 - 2.5e-10 40.1 0.6 5.8e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 CAR23099.1 - 0.00038 20.5 5.5 0.34 11.1 0.0 3.3 3 0 0 3 3 3 2 HAMP domain Daxx PF03344.10 CAR23099.1 - 0.051 12.0 26.7 0.1 11.0 18.5 1.4 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 CAR23099.1 - 0.089 10.4 7.0 2.8 5.5 3.7 2.4 2 0 0 2 2 2 0 Ycf1 Glyco_hydro_3_C PF01915.17 CAR23100.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AA_permease_2 PF13520.1 CAR23101.1 - 1.6e-63 214.7 40.7 2e-63 214.4 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR23101.1 - 2.4e-16 59.1 33.1 4e-16 58.4 22.9 1.2 1 0 0 1 1 1 1 Amino acid permease Pantoate_ligase PF02569.10 CAR23102.1 - 3.5e-105 350.7 0.0 3.9e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Avl9 PF09794.4 CAR23102.1 - 0.13 10.7 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 Ndc80_HEC PF03801.8 CAR23103.1 - 3.6e-57 192.2 2.2 1.1e-56 190.6 1.5 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family IncA PF04156.9 CAR23103.1 - 0.0003 20.4 39.3 0.00098 18.7 12.2 3.0 2 1 1 3 3 3 2 IncA protein Tropomyosin PF00261.15 CAR23103.1 - 0.0034 16.5 35.3 0.0041 16.2 6.4 2.5 2 0 0 2 2 2 2 Tropomyosin NPV_P10 PF05531.7 CAR23103.1 - 0.01 16.0 0.4 0.01 16.0 0.3 5.4 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 CAR23103.1 - 0.011 14.4 34.9 0.053 12.1 4.7 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.16 CAR23103.1 - 0.015 14.7 38.8 0.082 12.3 6.9 3.8 2 1 0 3 3 3 0 Intermediate filament protein YokU PF14122.1 CAR23103.1 - 0.015 14.9 0.1 0.057 13.1 0.1 2.0 1 0 0 1 1 1 0 YokU-like protein RNase_PH_C PF03725.10 CAR23103.1 - 0.06 13.2 0.0 8 6.4 0.0 2.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 YqbF PF14553.1 CAR23103.1 - 0.074 12.7 1.8 13 5.5 0.1 3.5 3 0 0 3 3 3 0 YqbF, hypothetical protein domain Cluap1 PF10234.4 CAR23103.1 - 0.16 11.1 0.0 0.16 11.1 0.0 4.7 3 2 1 4 4 4 0 Clusterin-associated protein-1 DUF869 PF05911.6 CAR23103.1 - 0.35 9.0 36.9 0.43 8.7 12.2 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Tropomyosin_1 PF12718.2 CAR23103.1 - 0.37 10.6 40.7 2 8.2 14.6 3.0 2 1 0 2 2 2 0 Tropomyosin like APG6 PF04111.7 CAR23103.1 - 1.4 7.9 33.8 1.9 7.4 9.6 2.8 2 1 0 2 2 2 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CAR23103.1 - 2.6 7.1 13.4 1.6 7.7 0.1 3.4 2 2 2 4 4 4 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CAR23103.1 - 4.5 7.1 40.0 1 9.2 7.5 3.9 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 CAR23103.1 - 6.5 6.9 39.0 0.079 13.1 3.6 5.8 2 2 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tektin PF03148.9 CAR23103.1 - 7.9 4.9 33.5 0.14 10.6 2.0 3.4 2 2 1 3 3 3 0 Tektin family Helicase_C_3 PF13625.1 CAR23104.1 - 9.2e-26 90.1 0.0 3.3e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR23104.1 - 2.4e-14 53.5 0.1 6.4e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CAR23104.1 - 1.1e-12 47.3 0.1 2e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR23104.1 - 1.4e-10 40.8 0.0 3.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR23104.1 - 1.2e-07 31.3 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 CAR23104.1 - 0.041 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein AAA_34 PF13872.1 CAR23104.1 - 0.052 12.3 0.0 0.094 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SPT6_acidic PF14632.1 CAR23104.1 - 0.93 9.6 5.9 0.16 12.1 0.7 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 SRP40_C PF05022.7 CAR23105.1 - 1.1e-29 102.7 5.4 1.1e-29 102.7 3.8 2.4 3 0 0 3 3 3 1 SRP40, C-terminal domain Whi5 PF08528.6 CAR23106.1 - 2.3e-10 39.7 0.1 4e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Whi5 like LIM PF00412.17 CAR23107.1 - 1.1e-14 54.2 24.9 8.9e-09 35.2 5.5 2.3 2 0 0 2 2 2 2 LIM domain Peptidase_M48 PF01435.13 CAR23108.1 - 8.7e-50 169.3 0.0 1.2e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 CAR23108.1 - 0.0065 15.6 0.1 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative metallopeptidase domain DUF2268 PF10026.4 CAR23108.1 - 0.017 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) TRAM_LAG1_CLN8 PF03798.11 CAR23109.1 - 7.9e-33 113.6 19.6 1e-32 113.2 13.6 1.2 1 0 0 1 1 1 1 TLC domain PfkB PF00294.19 CAR23110.1 - 3.1e-70 236.7 2.0 3.5e-70 236.5 1.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CAR23110.1 - 0.00012 21.4 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase STAT2_C PF12188.3 CAR23110.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal Na_Ca_ex PF01699.19 CAR23111.1 - 1.1e-45 154.6 26.4 7.2e-25 87.2 4.5 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Lipase_3 PF01764.20 CAR23112.1 - 1.2e-34 118.9 0.0 1.9e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) G-alpha PF00503.15 CAR23113.1 - 2.6e-112 375.3 0.0 2.9e-112 375.2 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CAR23113.1 - 7.9e-15 54.5 0.4 2.3e-10 39.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR23113.1 - 6.8e-05 22.1 1.0 0.0075 15.4 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR23113.1 - 0.001 19.5 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein CPSase_L_D2 PF02786.12 CAR23115.1 - 2.5e-109 363.4 0.0 5.7e-84 280.6 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 CAR23115.1 - 1.4e-37 129.2 0.5 4.6e-21 75.3 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_D3 PF02787.14 CAR23115.1 - 3.9e-37 126.7 0.1 9.3e-37 125.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CAR23115.1 - 3e-35 120.6 0.0 4e-16 59.0 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 CAR23115.1 - 3.7e-24 85.0 0.0 3.3e-10 39.2 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CAR23115.1 - 1.2e-20 73.6 0.1 4.3e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CAR23115.1 - 6.9e-17 61.5 0.3 8e-08 31.9 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CAR23115.1 - 2.6e-07 30.6 0.1 0.0079 16.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 CAR23115.1 - 8.6e-06 25.3 0.0 0.0075 15.7 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 CAR23115.1 - 1.1e-05 25.1 0.1 0.091 12.3 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 CAR23115.1 - 0.00057 19.1 0.0 0.1 11.7 0.0 2.7 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.16 CAR23115.1 - 0.0027 17.1 0.0 0.33 10.3 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family MGS PF02142.17 CAR23115.1 - 0.008 16.0 0.0 0.032 14.1 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Aldo_ket_red PF00248.16 CAR23116.1 - 8.9e-51 172.3 0.0 1e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_28 PF13518.1 CAR23116.1 - 0.014 15.3 0.1 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain OPT PF03169.10 CAR23117.1 - 7.6e-191 635.7 56.4 8.7e-191 635.5 39.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SNAP PF14938.1 CAR23118.1 - 5.7e-106 353.7 18.0 6.4e-106 353.6 12.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 CAR23118.1 - 0.0096 16.3 7.5 34 5.2 0.4 5.2 3 2 1 4 4 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CAR23118.1 - 0.043 13.2 2.3 0.059 12.8 0.3 2.0 1 1 0 2 2 2 0 Foie gras liver health family 1 Lambda_Kil PF06301.6 CAR23118.1 - 0.22 10.9 2.9 7.2 6.1 0.1 3.8 3 0 0 3 3 3 0 Bacteriophage lambda Kil protein TPR_16 PF13432.1 CAR23118.1 - 4.2 8.1 22.8 5 7.9 1.5 3.9 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAR23118.1 - 7.2 7.0 15.2 1.4 9.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat NAD_binding_6 PF08030.7 CAR23119.1 - 6.6e-22 78.0 0.0 1.3e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CAR23119.1 - 5.3e-21 74.4 0.0 1.1e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CAR23119.1 - 9.5e-19 67.7 13.8 2.1e-18 66.6 8.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF1769 PF08588.5 CAR23119.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Yippee-Mis18 PF03226.9 CAR23120.1 - 8e-17 61.0 7.8 1e-16 60.7 5.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.10 CAR23120.1 - 0.029 14.5 1.6 0.029 14.5 1.1 1.7 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Myotub-related PF06602.9 CAR23121.1 - 3.5e-129 430.6 0.7 4.8e-129 430.1 0.5 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 CAR23121.1 - 0.0023 18.2 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CAR23121.1 - 0.013 14.8 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GRAM PF02893.15 CAR23121.1 - 0.036 13.5 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 GRAM domain DSPc PF00782.15 CAR23121.1 - 0.039 13.5 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain CMD PF02627.15 CAR23122.1 - 1.6e-06 27.8 0.0 6.9e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Nnf1 PF03980.9 CAR23123.1 - 1e-25 89.8 8.0 1e-25 89.8 5.5 1.8 1 1 1 2 2 2 1 Nnf1 AAA_23 PF13476.1 CAR23123.1 - 0.065 13.5 6.5 0.12 12.6 4.5 1.5 1 1 0 1 1 1 0 AAA domain HHH_6 PF14579.1 CAR23123.1 - 0.089 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1366 PF07104.6 CAR23123.1 - 0.15 11.6 2.7 0.81 9.3 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1366) YlqD PF11068.3 CAR23123.1 - 0.18 11.8 7.0 0.06 13.3 2.9 1.7 2 1 0 2 2 2 0 YlqD protein DUF342 PF03961.8 CAR23123.1 - 0.19 10.0 2.9 0.25 9.7 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CAR23123.1 - 1 7.1 5.1 1.2 6.8 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.11 CAR23123.1 - 1.3 9.3 5.1 18 5.5 3.5 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Rho_Binding PF08912.6 CAR23123.1 - 1.8 8.9 9.8 2.4 8.5 0.1 3.0 3 0 0 3 3 3 0 Rho Binding NPV_P10 PF05531.7 CAR23123.1 - 2.2 8.5 5.6 2.5 8.4 0.3 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 CAR23123.1 - 2.4 8.2 7.5 0.55 10.3 2.7 1.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_4 PF12763.2 CAR23124.1 - 3.9e-34 116.5 1.1 1.3e-11 44.0 0.0 4.3 5 0 0 5 5 5 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 CAR23124.1 - 1.6e-07 30.9 0.0 5.1e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 CAR23124.1 - 1.7e-07 31.2 0.0 0.52 10.4 0.0 4.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR23124.1 - 2.7e-05 23.6 0.1 0.29 11.1 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 CAR23124.1 - 3.3e-05 22.8 0.0 0.05 12.9 0.0 3.8 3 0 0 3 3 3 1 EF hand Filament PF00038.16 CAR23124.1 - 0.0016 18.0 51.4 0.012 15.1 12.4 3.3 1 1 2 3 3 3 3 Intermediate filament protein UBA_4 PF14555.1 CAR23124.1 - 0.0017 17.8 0.1 0.0017 17.8 0.1 2.2 3 0 0 3 3 3 1 UBA-like domain APG6 PF04111.7 CAR23124.1 - 0.029 13.4 54.3 0.029 13.4 15.2 3.0 1 1 1 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CAR23124.1 - 0.04 13.6 61.5 0.85 9.3 16.6 4.9 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 CAR23124.1 - 1.5 7.9 26.1 0.44 9.6 0.2 3.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Spc7 PF08317.6 CAR23124.1 - 7.4 5.1 52.0 7.3 5.1 16.6 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein Noelin-1 PF12308.3 CAR23124.1 - 9.5 6.0 13.5 3 7.7 1.4 3.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein VanZ PF04892.7 CAR23125.1 - 0.00016 21.6 1.3 0.00027 20.9 0.9 1.4 1 1 0 1 1 1 1 VanZ like family Asp-Al_Ex PF06826.7 CAR23125.1 - 0.064 12.7 0.1 0.085 12.3 0.1 1.4 1 1 0 1 1 1 0 Predicted Permease Membrane Region Ribosomal_S7 PF00177.16 CAR23126.1 - 1e-30 106.2 0.2 1.6e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PPP4R2 PF09184.6 CAR23127.1 - 1e-35 123.7 22.1 2.1e-35 122.6 15.3 1.8 1 1 0 1 1 1 1 PPP4R2 BUD22 PF09073.5 CAR23127.1 - 5.1 6.0 21.1 8.7 5.2 14.6 1.4 1 0 0 1 1 1 0 BUD22 Peptidase_M16_C PF05193.16 CAR23128.1 - 1.6e-24 86.6 0.2 3.8e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CAR23128.1 - 4.3e-19 68.7 0.7 7.9e-19 67.8 0.5 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SDA1 PF05285.7 CAR23129.1 - 0.12 11.5 13.2 0.17 11.1 9.1 1.2 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.6 CAR23129.1 - 3.8 6.5 8.5 6.1 5.8 5.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.7 CAR23129.1 - 4.7 5.0 12.6 5.4 4.8 8.7 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CAR23129.1 - 9.3 4.1 10.5 11 3.9 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M20 PF01546.23 CAR23130.1 - 2.2e-21 76.2 0.0 3.1e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR23130.1 - 5.6e-12 45.3 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Proteasome PF00227.21 CAR23131.1 - 8.7e-37 126.2 0.0 8.6e-36 123.0 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit ER_lumen_recept PF00810.13 CAR23132.1 - 1.1e-50 171.9 12.6 1.8e-50 171.2 8.8 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor Thioredoxin PF00085.15 CAR23133.1 - 6.1e-11 41.9 0.0 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 CAR23133.1 - 0.002 18.1 0.0 0.03 14.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CAR23133.1 - 0.014 15.5 0.0 8.3 6.6 0.0 3.1 2 1 0 2 2 2 0 Thioredoxin-like domain Sod_Cu PF00080.15 CAR23134.1 - 1.3e-45 155.0 4.4 1.5e-45 154.8 3.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CTP_synth_N PF06418.9 CAR23135.1 - 2.3e-119 397.5 0.1 3.1e-119 397.1 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CAR23135.1 - 5.5e-57 192.3 0.0 8.3e-57 191.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CAR23135.1 - 0.0001 21.8 0.0 0.0004 19.8 0.0 2.0 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 CAR23135.1 - 0.015 14.6 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Nnf1 PF03980.9 CAR23136.1 - 0.022 14.7 2.1 0.022 14.7 1.4 2.3 2 0 0 2 2 2 0 Nnf1 DUF837 PF05769.6 CAR23136.1 - 0.36 10.3 8.0 0.85 9.1 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF837) ERM PF00769.14 CAR23136.1 - 1.1 8.7 16.3 1.4 8.3 11.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family NYD-SP28_assoc PF14775.1 CAR23136.1 - 2 8.1 8.2 14 5.4 0.1 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain APG6 PF04111.7 CAR23136.1 - 6.1 5.7 8.8 3 6.8 4.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 ESCRT-II PF05871.7 CAR23137.1 - 1.1e-43 148.4 0.9 1.1e-43 148.4 0.7 1.3 2 0 0 2 2 2 1 ESCRT-II complex subunit Sod_Fe_C PF02777.13 CAR23138.1 - 6e-14 51.7 0.3 1.4e-06 28.0 0.2 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Amidoligase_2 PF12224.3 CAR23138.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme Scramblase PF03803.10 CAR23139.1 - 3.1e-65 219.3 0.0 5.5e-64 215.2 0.0 2.0 1 1 0 1 1 1 1 Scramblase Peptidase_C12 PF01088.16 CAR23140.1 - 4.4e-59 199.2 0.0 8.4e-59 198.3 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SHOCT PF09851.4 CAR23140.1 - 0.002 17.5 0.4 0.002 17.5 0.3 2.7 3 0 0 3 3 3 1 Short C-terminal domain SAC3_GANP PF03399.11 CAR23141.1 - 1.2e-51 175.1 6.1 1.8e-51 174.5 4.2 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CAR23141.1 - 1.4e-06 28.1 2.3 6.1e-06 26.0 0.3 2.5 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 CAR23141.1 - 0.013 15.7 1.0 0.17 12.1 0.0 3.0 3 1 0 3 3 3 0 PCI domain Peptidase_C12 PF01088.16 CAR23142.1 - 9.9e-52 175.2 0.0 1.2e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Rpr2 PF04032.11 CAR23143.1 - 1.2e-13 50.7 0.2 2.2e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 CAR23143.1 - 0.0037 17.0 0.1 0.0075 16.0 0.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 CAR23143.1 - 0.0043 16.2 3.0 0.49 9.6 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-C2H2_3 PF13878.1 CAR23143.1 - 0.005 16.3 0.5 0.065 12.8 0.0 2.3 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO zinc_ribbon_2 PF13240.1 CAR23143.1 - 0.02 14.3 2.5 2 7.9 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF866 PF05907.8 CAR23143.1 - 0.059 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-CCHC PF00098.18 CAR23143.1 - 0.23 11.4 2.5 0.71 9.9 1.8 1.9 1 0 0 1 1 1 0 Zinc knuckle Pex24p PF06398.6 CAR23144.1 - 8.5e-79 264.9 2.8 1e-78 264.6 1.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PQQ_3 PF13570.1 CAR23145.1 - 8e-08 32.3 3.3 2.1 8.7 0.0 5.0 5 0 0 5 5 5 3 PQQ-like domain PQQ_2 PF13360.1 CAR23145.1 - 1.1e-06 28.3 0.3 1.5e-05 24.6 0.2 2.1 1 1 0 1 1 1 1 PQQ-like domain WD40 PF00400.27 CAR23145.1 - 0.00018 21.2 5.0 0.0097 15.7 0.0 4.5 6 0 0 6 6 6 1 WD domain, G-beta repeat PQQ PF01011.16 CAR23145.1 - 0.0021 17.5 3.4 0.026 14.0 0.0 3.9 5 0 0 5 5 5 1 PQQ enzyme repeat SET PF00856.23 CAR23146.1 - 1.5e-13 51.3 0.1 3.9e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 CAR23147.1 - 2.5e-54 180.7 27.7 1.5e-15 56.6 0.1 6.3 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 CAR23147.1 - 1.8e-42 141.2 25.3 4.6e-07 29.1 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 CAR23147.1 - 2.7e-34 114.3 25.8 7.7e-05 22.3 0.1 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 CAR23147.1 - 1.5e-21 76.1 13.7 1.2e-09 37.9 0.9 6.0 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CAR23147.1 - 2.2e-21 75.9 11.4 7.5e-05 23.2 0.0 6.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CAR23147.1 - 3.4e-21 73.3 19.9 0.00076 19.0 0.2 8.4 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 CAR23147.1 - 2.7e-18 64.8 9.7 0.13 12.9 0.0 9.1 6 3 3 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 CAR23147.1 - 3.8e-15 54.3 14.5 5.6e-05 22.6 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAR23147.1 - 3.7e-12 46.3 17.0 0.0044 17.3 0.2 7.2 4 3 3 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 CAR23147.1 - 1.7e-08 34.4 16.8 0.032 14.3 0.2 4.8 2 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CAR23147.1 - 4.8e-07 29.4 10.6 0.32 11.2 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR23147.1 - 1.9e-06 27.6 5.0 0.0013 18.5 0.1 5.5 6 2 1 7 7 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAR23147.1 - 5.1e-06 26.2 1.1 0.16 11.9 0.0 5.3 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAR23147.1 - 0.00024 21.3 22.7 2 9.0 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 CAR23147.1 - 0.0011 18.1 4.0 13 5.1 0.0 5.7 6 0 0 6 6 6 0 SHNi-TPR DUF3808 PF10300.4 CAR23147.1 - 0.0015 17.1 0.3 0.0015 17.1 0.2 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) PPR PF01535.15 CAR23147.1 - 0.0027 17.5 1.5 54 4.0 0.0 5.8 6 0 0 6 6 6 0 PPR repeat Fis1_TPR_C PF14853.1 CAR23147.1 - 0.004 16.9 3.7 20 5.1 0.1 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Rep_Org_C PF06926.6 CAR23147.1 - 0.021 14.9 0.4 9.5 6.4 0.1 2.7 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus Foie-gras_1 PF11817.3 CAR23147.1 - 0.021 14.3 9.1 5.5 6.3 5.0 3.6 1 1 1 2 2 2 0 Foie gras liver health family 1 MIT PF04212.13 CAR23147.1 - 0.1 12.4 14.7 17 5.3 0.1 5.9 3 2 2 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 CAR23147.1 - 0.14 12.2 8.7 3.6 7.7 0.1 4.5 4 3 0 4 4 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 CAR23147.1 - 0.42 10.6 2.9 1e+02 2.9 0.0 4.6 6 0 0 6 6 5 0 PPR repeat family DUF1771 PF08590.5 CAR23147.1 - 0.94 9.5 13.1 1.3 9.0 0.4 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1771) XPC-binding PF09280.6 CAR23147.1 - 1.3 8.5 12.2 0.17 11.3 2.0 3.1 2 1 0 2 2 2 0 XPC-binding domain TPR_3 PF07720.7 CAR23147.1 - 6.7 6.6 17.1 6.5 6.6 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3275 PF11679.3 CAR23147.1 - 8.9 5.8 13.1 0.45 10.1 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) AAA_2 PF07724.9 CAR23148.1 - 2e-52 177.5 0.1 5.4e-50 169.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CAR23148.1 - 8.2e-24 83.3 0.4 8.2e-24 83.3 0.3 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CAR23148.1 - 1.9e-22 79.8 0.1 2e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAR23148.1 - 3.3e-16 59.2 1.4 5.3e-12 45.6 0.0 4.0 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR23148.1 - 2.5e-14 53.6 2.9 0.00023 21.2 0.0 4.8 3 2 2 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 CAR23148.1 - 7.9e-09 35.7 0.0 0.0017 18.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CAR23148.1 - 3.5e-08 33.4 5.7 0.0006 19.5 0.3 4.5 3 2 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 CAR23148.1 - 4.6e-08 33.0 0.0 0.0083 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CAR23148.1 - 2.4e-07 30.3 0.1 1.1e-05 24.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 CAR23148.1 - 1.5e-06 29.0 4.9 0.015 16.1 0.0 4.0 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 CAR23148.1 - 3.6e-06 26.5 0.0 0.041 13.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.22 CAR23148.1 - 2.6e-05 24.5 0.5 0.074 13.3 0.0 3.4 3 1 0 3 3 3 1 ABC transporter LacI PF00356.16 CAR23148.1 - 3.6e-05 23.2 0.0 0.075 12.6 0.0 3.9 4 0 0 4 4 3 1 Bacterial regulatory proteins, lacI family AAA_18 PF13238.1 CAR23148.1 - 4.9e-05 23.6 7.5 0.041 14.1 0.1 3.5 4 1 0 4 4 2 2 AAA domain Zeta_toxin PF06414.7 CAR23148.1 - 9.8e-05 21.5 0.0 0.0023 17.0 0.0 2.8 2 1 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 CAR23148.1 - 0.00012 22.0 0.2 0.39 10.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CAR23148.1 - 0.00013 21.1 0.0 0.031 13.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CAR23148.1 - 0.00014 21.8 0.1 0.025 14.5 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 CAR23148.1 - 0.00015 21.4 0.0 0.086 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 CAR23148.1 - 0.00024 21.1 0.4 2.4 8.0 0.0 3.8 2 1 1 4 4 3 1 AAA domain MobB PF03205.9 CAR23148.1 - 0.00032 20.4 0.0 0.29 10.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CAR23148.1 - 0.00036 20.0 0.0 0.085 12.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 CAR23148.1 - 0.00052 19.5 0.0 0.44 10.0 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 CAR23148.1 - 0.00057 18.8 1.0 0.52 9.1 0.1 3.5 2 2 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CAR23148.1 - 0.00058 19.9 0.0 1.3 9.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.1 CAR23148.1 - 0.00061 19.4 0.2 1.4 8.6 0.0 2.8 3 0 0 3 3 2 2 Part of AAA domain AAA_30 PF13604.1 CAR23148.1 - 0.00092 18.8 0.5 0.62 9.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 CAR23148.1 - 0.00094 18.1 2.8 0.018 13.9 1.1 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 CAR23148.1 - 0.0013 18.1 1.9 0.33 10.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CAR23148.1 - 0.0014 17.8 0.1 0.67 9.0 0.0 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 CAR23148.1 - 0.0026 17.6 2.8 2.9 7.6 0.0 4.3 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit UPF0079 PF02367.12 CAR23148.1 - 0.0032 17.0 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 CAR23148.1 - 0.0039 17.0 0.9 0.68 9.7 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 SRP54 PF00448.17 CAR23148.1 - 0.0056 16.1 0.0 1.1 8.6 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 CAR23148.1 - 0.0086 14.7 0.0 0.8 8.2 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_3 PF07726.6 CAR23148.1 - 0.012 15.1 0.1 0.28 10.7 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 CAR23148.1 - 0.014 15.2 0.0 0.041 13.7 0.0 1.8 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.1 CAR23148.1 - 0.02 14.7 0.0 3.7 7.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CAR23148.1 - 0.021 14.3 0.0 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CAR23148.1 - 0.021 14.3 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PhoH PF02562.11 CAR23148.1 - 0.022 13.9 0.0 2.6 7.2 0.0 2.8 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.10 CAR23148.1 - 0.029 14.1 0.2 21 4.8 0.0 3.3 3 0 0 3 3 3 0 NTPase Miro PF08477.8 CAR23148.1 - 0.03 14.8 0.0 0.67 10.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_6 PF12774.2 CAR23148.1 - 0.05 13.1 0.2 13 5.2 0.2 2.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_23 PF13476.1 CAR23148.1 - 0.28 11.5 14.5 3.6 7.8 0.1 3.3 2 2 0 2 2 2 0 AAA domain bZIP_1 PF00170.16 CAR23149.1 - 3.2e-07 30.2 12.4 1e-06 28.6 8.6 1.9 1 1 0 1 1 1 1 bZIP transcription factor Sporozoite_P67 PF05642.6 CAR23149.1 - 0.087 10.6 4.4 0.12 10.2 3.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HALZ PF02183.13 CAR23149.1 - 0.14 11.9 5.2 0.092 12.4 0.5 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ribosomal_60s PF00428.14 CAR23149.1 - 0.39 11.1 5.6 3 8.2 2.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein SPT16 PF08644.6 CAR23149.1 - 0.5 10.2 2.6 3.5 7.4 0.3 2.1 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) ALMS_motif PF15309.1 CAR23149.1 - 0.58 9.9 9.6 0.056 13.2 1.5 2.0 2 0 0 2 2 2 0 ALMS motif bZIP_Maf PF03131.12 CAR23149.1 - 2 8.7 19.6 0.095 13.0 4.3 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Apc13p PF05839.6 CAR23150.1 - 0.00032 20.6 0.3 0.00066 19.6 0.2 1.5 1 0 0 1 1 1 1 Apc13p protein PalH PF08733.5 CAR23151.1 - 1e-65 221.8 15.3 1.3e-65 221.5 10.6 1.1 1 0 0 1 1 1 1 PalH/RIM21 Fasciclin PF02469.17 CAR23152.1 - 0.0019 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain HLH PF00010.21 CAR23153.1 - 4.3e-19 67.9 0.7 8.9e-19 66.9 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CtsR PF05848.6 CAR23153.1 - 0.091 12.7 0.1 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Firmicute transcriptional repressor of class III stress genes (CtsR) XPG_N PF00752.12 CAR23154.1 - 2.8e-25 88.4 0.0 5.8e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CAR23154.1 - 4.8e-21 74.6 0.0 1.4e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CAR23154.1 - 0.00028 21.0 0.0 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 CAR23154.1 - 0.0036 16.8 0.0 0.0094 15.4 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing HHH_2 PF12826.2 CAR23154.1 - 0.0046 16.8 0.0 0.11 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif TPR_2 PF07719.12 CAR23154.1 - 0.033 14.1 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR23154.1 - 0.084 12.6 0.0 0.33 10.8 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAR23154.1 - 0.099 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.2 CAR23155.1 - 2.4e-41 139.9 0.0 1e-15 57.8 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CAR23155.1 - 9.2e-29 97.8 0.1 3.2e-07 29.8 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CAR23155.1 - 1.5e-24 85.4 1.2 7e-08 32.4 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR23155.1 - 8e-23 78.2 0.1 6.9e-05 22.7 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CAR23155.1 - 5.1e-22 77.8 0.2 2.2e-07 31.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CAR23155.1 - 2.3e-21 75.9 1.1 2.3e-21 75.9 0.8 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase UNC45-central PF11701.3 CAR23156.1 - 7.5e-21 74.4 1.6 7.5e-21 74.4 1.1 2.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Pex2_Pex12 PF04757.9 CAR23157.1 - 3.9e-33 114.7 3.4 5e-33 114.4 2.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CAR23157.1 - 8.9e-09 35.2 12.6 1.6e-08 34.4 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR23157.1 - 2.9e-08 33.2 10.4 5.5e-08 32.3 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR23157.1 - 5.3e-08 32.5 12.4 8.8e-08 31.8 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CAR23157.1 - 1.2e-07 31.2 12.2 1.8e-07 30.6 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR23157.1 - 4.2e-06 26.3 8.4 7.5e-06 25.5 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAR23157.1 - 0.0015 18.3 13.1 0.0028 17.4 9.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CAR23157.1 - 0.01 15.9 8.5 0.024 14.7 5.8 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CAR23157.1 - 0.012 15.3 9.4 0.046 13.4 5.6 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 CAR23157.1 - 0.047 13.5 4.0 0.084 12.7 2.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 CAR23157.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 U-box domain IBR PF01485.16 CAR23157.1 - 0.62 9.9 10.8 1.5 8.7 7.5 1.7 1 1 0 1 1 1 0 IBR domain zf-C3HC4_3 PF13920.1 CAR23158.1 - 1.2e-07 31.2 7.8 1.2e-07 31.2 5.4 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR23158.1 - 0.0053 16.3 10.8 0.0053 16.3 7.5 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR23158.1 - 0.012 15.6 10.5 0.012 15.6 7.3 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UPF0158 PF03682.8 CAR23158.1 - 0.44 10.1 3.0 1.9 8.0 1.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) Prok-RING_4 PF14447.1 CAR23158.1 - 0.53 9.8 6.2 0.14 11.7 1.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PGP_phosphatase PF09419.5 CAR23159.1 - 7.6e-67 223.8 0.0 8.7e-67 223.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 CAR23159.1 - 2.8e-05 23.7 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CAR23159.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAT PF02259.18 CAR23160.1 - 3.1e-71 240.2 9.3 9.4e-71 238.6 6.4 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CAR23160.1 - 9.3e-40 136.5 5.4 9.5e-40 136.5 0.2 3.7 5 0 0 5 5 5 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CAR23160.1 - 1e-08 34.4 0.0 3.3e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 CAR23160.1 - 0.01 15.4 1.4 0.078 12.6 0.2 2.9 2 1 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 CAR23160.1 - 0.055 13.4 2.6 6.1 6.8 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 CAR23161.1 - 1.4e-52 178.8 29.5 4.5e-52 177.1 20.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR23161.1 - 2e-18 66.2 31.2 2e-18 66.2 21.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 CAR23161.1 - 0.0044 15.7 2.7 0.03 13.0 1.9 2.0 1 1 0 1 1 1 1 BT1 family DUF606 PF04657.8 CAR23161.1 - 0.06 13.4 16.9 0.11 12.6 2.7 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF606 Asp PF00026.18 CAR23162.1 - 4.9e-30 104.8 0.4 4.1e-29 101.8 0.3 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR23162.1 - 0.00021 21.2 0.0 0.0047 16.8 0.0 2.8 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Sec23_trunk PF04811.10 CAR23163.1 - 2.3e-55 187.6 0.5 6.7e-55 186.0 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CAR23163.1 - 3.1e-18 65.0 0.4 7.9e-18 63.7 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CAR23163.1 - 2e-13 50.6 0.0 4.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CAR23163.1 - 2e-11 43.2 2.2 5.1e-11 41.9 1.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CAR23163.1 - 0.00035 20.1 0.0 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat UPF0047 PF01894.12 CAR23163.1 - 0.067 12.9 0.1 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0047 Pal1 PF08316.6 CAR23165.1 - 4.2e-53 179.5 3.4 4.2e-53 179.5 2.4 2.5 3 0 0 3 3 3 1 Pal1 cell morphology protein Bul1_N PF04425.7 CAR23165.1 - 0.036 12.6 2.7 0.055 12.0 1.9 1.2 1 0 0 1 1 1 0 Bul1 N terminus Macoilin PF09726.4 CAR23165.1 - 0.84 7.8 8.7 0.99 7.6 6.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 CAR23165.1 - 9.7 4.9 12.1 19 3.9 8.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sod_Fe_C PF02777.13 CAR23166.1 - 7.7e-09 35.3 0.1 0.0018 18.0 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Svf1 PF08622.5 CAR23167.1 - 3.9e-134 446.7 0.8 4.5e-134 446.5 0.6 1.0 1 0 0 1 1 1 1 Svf1-like Sugar_tr PF00083.19 CAR23168.1 - 1.7e-166 554.3 33.2 1.9e-166 554.1 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR23168.1 - 1.8e-36 125.6 40.9 4.9e-30 104.4 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CAR23168.1 - 0.026 12.6 3.1 0.045 11.8 2.1 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Sugar_tr PF00083.19 CAR23169.1 - 2.3e-172 573.6 35.0 2.7e-172 573.4 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR23169.1 - 1.6e-29 102.7 30.0 1.1e-26 93.4 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_N PF00033.14 CAR23169.1 - 0.0011 18.3 0.3 0.0011 18.3 0.2 3.0 4 0 0 4 4 4 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 CAR23169.1 - 0.018 14.4 6.6 0.024 14.0 0.3 3.1 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 tRNA-synt_1d PF00750.14 CAR23171.1 - 7.9e-99 330.8 2.8 9.8e-99 330.5 2.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CAR23171.1 - 2.4e-30 104.9 0.7 5.5e-29 100.5 0.2 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CAR23171.1 - 2.6e-07 31.0 0.0 1e-06 29.1 0.0 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain VD10_N PF08476.5 CAR23171.1 - 0.062 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Viral D10 N-terminal KRAP_IP3R_bind PF14722.1 CAR23171.1 - 0.092 12.3 0.0 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Fcf1 PF04900.7 CAR23172.1 - 1.9e-38 130.5 0.1 3.8e-38 129.6 0.1 1.5 1 0 0 1 1 1 1 Fcf1 DUF4112 PF13430.1 CAR23173.1 - 1.6e-33 114.8 0.1 2e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) ING PF12998.2 CAR23174.1 - 8.9e-21 74.1 2.2 1.2e-20 73.6 1.6 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CAR23174.1 - 1.8e-10 40.3 8.7 3.7e-10 39.3 6.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CAR23174.1 - 0.0009 19.3 0.9 0.0018 18.4 0.2 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain MatE PF01554.13 CAR23175.1 - 3.7e-59 198.9 34.6 2e-34 118.5 5.3 2.7 3 0 0 3 3 3 2 MatE Abhydrolase_1 PF00561.15 CAR23176.1 - 2.4e-15 56.7 0.0 5e-14 52.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR23176.1 - 7.9e-11 42.2 0.0 1.2e-07 31.8 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR23176.1 - 0.0011 18.6 0.0 0.014 15.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAR23176.1 - 0.0057 16.1 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ribosomal_S15 PF00312.17 CAR23177.1 - 3.1e-26 90.9 1.2 6.8e-26 89.8 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3487 PF11990.3 CAR23177.1 - 0.01 15.1 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) ResIII PF04851.10 CAR23178.1 - 0.02 14.7 0.0 0.066 13.0 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CAR23178.1 - 0.023 14.4 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Gar1 PF04410.9 CAR23179.1 - 2.3e-43 147.3 2.3 2.8e-43 147.0 0.0 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region MMR_HSR1 PF01926.18 CAR23180.1 - 2.2e-18 66.3 0.0 4.2e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR23180.1 - 4.1e-07 29.6 0.0 2.7e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CAR23180.1 - 2.1e-06 27.6 0.0 0.12 12.2 0.0 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CAR23180.1 - 2.6e-05 23.4 0.0 5.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CAR23180.1 - 8.4e-05 21.8 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 CAR23180.1 - 0.0016 17.5 0.1 0.0028 16.7 0.1 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 CAR23180.1 - 0.0034 16.6 0.0 0.015 14.5 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CAR23180.1 - 0.0063 16.0 0.2 1.9 7.9 0.2 3.0 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CAR23180.1 - 0.031 13.7 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CAR23180.1 - 0.032 14.5 0.4 0.19 12.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Abhydrolase_3 PF07859.8 CAR23182.1 - 1.1e-60 204.8 0.1 1.4e-60 204.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CAR23182.1 - 1.2e-09 37.4 0.0 4.1e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CAR23182.1 - 9.5e-05 21.7 0.1 0.00052 19.2 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CAR23182.1 - 0.0049 15.5 0.0 0.008 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CAR23182.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family D-ser_dehydrat PF14031.1 CAR23183.1 - 3.5e-21 75.2 0.0 6.4e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CAR23183.1 - 1.9e-11 43.9 0.0 2.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fungal_trans PF04082.13 CAR23184.1 - 6.6e-53 179.2 3.7 6.6e-53 179.2 2.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 CAR23184.1 - 0.0023 18.1 8.8 0.011 15.9 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR23184.1 - 0.0024 18.0 12.8 0.0037 17.4 1.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger MFS_1 PF07690.11 CAR23185.1 - 2.2e-32 112.1 19.7 2.8e-32 111.8 10.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 CAR23185.1 - 0.01 15.3 9.5 0.011 15.2 5.0 2.2 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF2530 PF10745.4 CAR23185.1 - 0.27 11.2 8.7 8.7 6.4 0.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Ribonuc_L-PSP PF01042.16 CAR23186.1 - 1.9e-23 82.4 0.2 2.4e-23 82.1 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_M20 PF01546.23 CAR23187.1 - 5e-25 88.0 0.1 7e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 CAR23187.1 - 8.5e-07 28.8 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 CAR23187.1 - 2.5e-06 27.2 0.0 4.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 CAR23188.1 - 1.1e-39 136.1 21.7 3.5e-39 134.5 14.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.3 CAR23188.1 - 0.0014 17.8 0.5 0.021 14.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) DUF1228 PF06779.9 CAR23188.1 - 0.0043 17.0 3.1 2.5 8.1 0.1 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) ESSS PF10183.4 CAR23188.1 - 0.071 13.5 2.1 0.08 13.3 0.1 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COX6C PF02937.10 CAR23188.1 - 0.11 12.4 0.8 4.1 7.3 0.1 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DUF443 PF04276.7 CAR23188.1 - 1.3 8.4 9.3 0.29 10.5 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF443) DUF3353 PF11833.3 CAR23188.1 - 5.7 6.3 9.7 2.1 7.7 2.3 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3353) Fungal_trans PF04082.13 CAR23189.1 - 1.8e-23 82.7 0.2 3.5e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR23189.1 - 0.00023 21.0 10.3 0.00062 19.6 7.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 CAR23190.1 - 8.1e-41 139.6 0.1 1e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_M20 PF01546.23 CAR23191.1 - 1.4e-27 96.4 0.0 1.8e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 CAR23191.1 - 1.7e-05 24.6 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 CAR23191.1 - 0.00079 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain APG6 PF04111.7 CAR23192.1 - 0.3 10.0 13.6 0.66 8.9 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 C2-set PF05790.10 CAR23192.1 - 1 9.3 5.4 5.5 7.0 2.1 2.5 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Viral_P18 PF04521.8 CAR23192.1 - 2.1 7.7 11.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein IFP_35_N PF07334.8 CAR23192.1 - 6.6 6.7 12.6 4.2 7.4 0.1 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Brix PF04427.13 CAR23193.1 - 7e-43 146.5 2.9 1.1e-42 145.8 2.0 1.2 1 0 0 1 1 1 1 Brix domain DUF1764 PF08576.5 CAR23193.1 - 0.83 10.4 5.4 1.8 9.3 3.8 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) RhoGEF PF00621.15 CAR23194.1 - 8.2e-15 55.1 2.7 8.2e-15 55.1 1.8 1.6 2 0 0 2 2 2 1 RhoGEF domain SBDS PF01172.13 CAR23195.1 - 2.2e-14 52.9 0.5 2.6e-14 52.7 0.3 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SNF2_N PF00176.18 CAR23196.1 - 1.2e-77 260.6 0.5 2.5e-77 259.6 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 CAR23196.1 - 2.7e-16 59.0 7.8 2.7e-16 59.0 5.4 2.5 3 0 0 3 3 3 1 HSA Helicase_C PF00271.26 CAR23196.1 - 5.2e-14 51.8 0.0 1.5e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR23196.1 - 6e-07 29.1 0.0 2.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RRM_1 PF00076.17 CAR23197.1 - 4e-44 148.1 0.0 1.7e-16 59.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR23197.1 - 1e-27 95.9 0.0 7.3e-08 32.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR23197.1 - 2.9e-17 62.2 0.0 1.9e-09 37.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CAR23197.1 - 0.0053 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 CAR23197.1 - 0.012 15.3 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ipi1_N PF12333.3 CAR23198.1 - 7.2e-29 99.7 0.2 2.7e-28 97.9 0.2 2.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Tcf25 PF04910.9 CAR23199.1 - 4.5e-75 252.8 0.5 6.8e-75 252.2 0.4 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF807 PF05660.6 CAR23199.1 - 0.0017 18.0 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Coxiella burnetii protein of unknown function (DUF807) STE PF02200.11 CAR23200.1 - 6e-59 196.9 4.1 9.6e-59 196.3 2.9 1.3 1 0 0 1 1 1 1 STE like transcription factor DAGK_cat PF00781.19 CAR23200.1 - 0.16 11.4 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF2731 PF10806.3 CAR23201.1 - 8.2e-41 139.1 0.1 1.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) ResIII PF04851.10 CAR23202.1 - 2.8e-24 85.9 0.0 9.5e-24 84.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR23202.1 - 3.1e-15 56.0 0.0 8e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR23202.1 - 3e-14 52.6 0.2 4e-13 49.0 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 CAR23202.1 - 0.00049 19.1 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CAR23202.1 - 0.0032 17.5 0.1 0.034 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain SNF2_N PF00176.18 CAR23202.1 - 0.043 12.6 0.0 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain Pkinase PF00069.20 CAR23203.1 - 3.4e-48 164.0 1.4 6.6e-47 159.8 0.9 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23203.1 - 1.9e-22 79.5 0.1 4.9e-21 74.9 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23203.1 - 0.00027 20.0 0.0 0.00071 18.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CAR23203.1 - 0.0061 15.9 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CAR23203.1 - 0.26 10.9 0.0 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C13 PF01650.13 CAR23204.1 - 1.2e-47 162.4 1.4 2e-47 161.6 1.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family Thioredoxin_7 PF13899.1 CAR23205.1 - 8.3e-17 60.9 0.1 1.4e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 CAR23205.1 - 9.3e-17 60.8 0.4 1.3e-15 57.1 0.0 2.4 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 CAR23205.1 - 5.8e-13 48.1 0.4 1.2e-12 47.1 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.1 CAR23205.1 - 0.025 14.7 0.1 0.07 13.3 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Sas10_Utp3 PF04000.10 CAR23206.1 - 5.9e-07 29.5 1.2 1.6e-06 28.1 0.8 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CCDC32 PF14989.1 CAR23206.1 - 0.078 12.8 0.6 0.078 12.8 0.4 2.1 3 0 0 3 3 3 0 Coiled-coil domain containing 32 Rsc14 PF08586.5 CAR23206.1 - 1.1 9.7 4.6 0.52 10.8 0.5 2.3 2 1 1 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit Peroxin-3 PF04882.7 CAR23208.1 - 3e-110 368.8 16.2 3.5e-110 368.7 11.2 1.0 1 0 0 1 1 1 1 Peroxin-3 Skp1 PF01466.14 CAR23209.1 - 8e-37 125.1 0.2 1.6e-36 124.1 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CAR23209.1 - 3e-13 49.6 0.0 1.2e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain DUF1743 PF08489.6 CAR23209.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) ELH PF02323.10 CAR23209.1 - 0.14 11.2 1.1 0.18 10.8 0.4 1.3 1 1 0 1 1 1 0 Egg-laying hormone precursor GRAM PF02893.15 CAR23210.1 - 4.2e-19 67.8 0.0 9.2e-19 66.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Pkinase PF00069.20 CAR23211.1 - 2e-44 151.6 0.0 3.4e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 CAR23211.1 - 2.4e-40 137.3 0.0 5.5e-40 136.1 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 CAR23211.1 - 1.3e-25 89.9 0.0 7.7e-25 87.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 CAR23211.1 - 9.2e-05 21.7 0.4 0.13 11.8 0.0 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 CAR23211.1 - 0.00026 20.5 0.0 0.00079 18.9 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 CAR23211.1 - 0.0061 15.6 0.1 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cnd3 PF12719.2 CAR23212.1 - 1.7e-95 319.4 3.6 1.8e-95 319.4 1.5 1.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CAR23212.1 - 1.7e-08 34.6 0.3 0.00014 22.1 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CAR23212.1 - 1.6e-05 24.5 1.3 4.2 7.7 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 CAR23212.1 - 0.022 15.2 0.4 3.1 8.4 0.1 4.0 3 1 0 3 3 3 0 HEAT-like repeat WD40 PF00400.27 CAR23213.1 - 1.5e-11 43.7 17.3 0.0047 16.7 0.0 8.1 9 0 0 9 9 9 5 WD domain, G-beta repeat ABA_GPCR PF12430.3 CAR23214.1 - 7.3e-62 207.9 1.9 7.3e-62 207.9 1.3 2.3 2 1 1 3 3 3 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CAR23214.1 - 5.7e-19 67.9 0.0 2.8e-18 65.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) SpoIIIAC PF06686.6 CAR23214.1 - 0.027 14.2 0.1 0.11 12.3 0.1 2.1 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family FYVE PF01363.16 CAR23215.1 - 2.4e-21 75.3 27.4 2.4e-17 62.5 2.1 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 CAR23215.1 - 0.0016 17.9 0.2 0.0016 17.9 0.1 3.1 3 0 0 3 3 3 1 Rabenosyn Rab binding domain DUF2396 PF09654.5 CAR23215.1 - 0.0073 16.2 0.8 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2396) Ribosomal_L12 PF00542.14 CAR23215.1 - 0.02 14.9 0.5 0.087 12.8 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain HypA PF01155.14 CAR23215.1 - 2.9 7.6 19.5 0.84 9.3 0.7 3.2 3 1 0 3 3 3 0 Hydrogenase expression/synthesis hypA family MIF4G PF02854.14 CAR23216.1 - 2.9e-32 111.8 38.9 2.8e-16 59.5 2.9 4.3 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 CAR23216.1 - 6.1e-24 84.6 18.9 6.1e-24 84.6 13.1 2.5 1 1 1 2 2 2 1 Up-frameshift suppressor 2 SpoIIE PF07228.7 CAR23217.1 - 3e-35 121.6 0.0 3.8e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CAR23217.1 - 3e-06 26.7 0.2 6.8e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CAR23217.1 - 8.1e-06 25.4 0.1 0.0057 16.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C ATP-synt_E PF05680.7 CAR23218.1 - 2.7e-18 65.7 1.2 2.7e-18 65.6 0.8 1.0 1 0 0 1 1 1 1 ATP synthase E chain DUF4591 PF15261.1 CAR23218.1 - 0.00069 19.8 1.5 0.00088 19.5 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4591) Spore_III_AF PF09581.5 CAR23218.1 - 0.017 15.0 1.0 0.018 14.9 0.7 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DivIC PF04977.10 CAR23218.1 - 0.049 13.1 1.9 0.063 12.7 1.3 1.2 1 0 0 1 1 1 0 Septum formation initiator PBP PF01161.15 CAR23219.1 - 3.1e-13 49.8 0.1 5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_M1 PF01433.15 CAR23220.1 - 2.2e-121 405.6 0.0 3.7e-121 404.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CAR23220.1 - 4.3e-24 85.3 0.1 6.2e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CAR23220.1 - 4.4e-15 55.8 0.0 9.5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Glyco_hydro_76 PF03663.9 CAR23221.1 - 8.7e-146 486.0 17.7 1.1e-145 485.6 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ChAPs PF09295.5 CAR23222.1 - 2.8e-152 507.0 0.0 3.5e-152 506.7 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.12 CAR23222.1 - 0.00043 19.9 5.9 0.0079 16.0 0.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR23222.1 - 0.0071 16.0 0.0 2 8.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR23222.1 - 0.017 15.7 10.0 3.6 8.4 0.7 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAR23222.1 - 0.041 14.5 13.4 1.3 9.7 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAR23222.1 - 0.14 11.7 2.9 1.1 8.9 0.1 2.7 2 0 0 2 2 2 0 TPR repeat TFIID-31kDa PF02291.10 CAR23223.1 - 1.2e-52 177.1 0.1 1.3e-52 176.9 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit MBF1 PF08523.5 CAR23224.1 - 5.7e-26 90.3 0.4 5.7e-26 90.3 0.3 1.9 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CAR23224.1 - 4.2e-14 52.1 0.6 7.7e-14 51.2 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.1 CAR23224.1 - 6.6e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CAR23224.1 - 1.7e-05 24.8 0.1 2.7e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DBP PF12361.3 CAR23224.1 - 0.0063 16.0 1.4 0.0071 15.9 0.9 1.1 1 0 0 1 1 1 1 Duffy-antigen binding protein LRR_6 PF13516.1 CAR23225.1 - 2.2e-10 39.4 7.4 4.2 7.7 0.0 8.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.28 CAR23225.1 - 1.2e-07 30.7 5.2 7.3 7.0 0.0 7.5 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_4 PF12799.2 CAR23225.1 - 1.6e-07 30.7 11.7 0.0082 15.7 2.0 5.5 4 1 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CAR23225.1 - 0.00035 20.3 8.2 3.3 8.3 0.0 6.3 6 0 0 6 6 6 1 Leucine rich repeat LRR_8 PF13855.1 CAR23225.1 - 0.0007 19.3 12.0 2.6 7.8 1.0 5.5 3 2 2 5 5 5 3 Leucine rich repeat Allexi_40kDa PF05549.6 CAR23225.1 - 0.069 12.4 1.0 0.11 11.7 0.7 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein AATF-Che1 PF13339.1 CAR23225.1 - 0.39 10.8 4.8 0.84 9.7 3.4 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TFIIA PF03153.8 CAR23225.1 - 0.93 9.3 10.1 1.3 8.8 7.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acyltransferase PF01553.16 CAR23226.1 - 0.00045 19.6 0.0 0.0014 18.0 0.0 1.9 2 1 0 2 2 2 1 Acyltransferase CybS PF05328.7 CAR23227.1 - 1.3e-50 170.4 0.0 1.6e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 CAR23227.1 - 0.0076 16.0 0.6 0.19 11.5 0.4 2.2 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Cauli_VI PF01693.11 CAR23228.1 - 2.1e-26 91.6 0.5 5.9e-18 64.6 0.0 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 CAR23228.1 - 2.5e-26 92.5 0.1 4.4e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 RNase H Membr_traf_MHD PF10540.4 CAR23229.1 - 2.7e-13 49.8 0.0 1.2e-12 47.7 0.0 2.2 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CAR23229.1 - 9.8e-08 31.7 0.2 2.3e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 CAR23229.1 - 4.6e-05 21.9 0.0 4.6e-05 21.9 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF810) SWIB PF02201.13 CAR23230.1 - 9.3e-25 86.1 0.7 1.8e-24 85.2 0.5 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 CAR23230.1 - 1.1e-09 37.9 0.2 2e-08 33.8 0.1 2.5 2 0 0 2 2 2 1 DEK C terminal domain Sas10 PF09368.5 CAR23230.1 - 0.027 14.6 5.2 0.056 13.6 3.6 1.5 1 0 0 1 1 1 0 Sas10 C-terminal domain RRS1 PF04939.7 CAR23231.1 - 1.5e-62 209.9 5.0 1.7e-62 209.7 3.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) VPS11_C PF12451.3 CAR23233.1 - 1.2e-13 50.6 0.4 4.1e-13 48.9 0.2 2.0 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.1 CAR23233.1 - 1.4e-05 25.0 5.6 3.5e-05 23.7 3.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR23233.1 - 2.4e-05 24.0 5.8 6e-05 22.7 4.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR23233.1 - 0.00064 19.3 6.8 0.00064 19.3 4.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAR23233.1 - 0.0021 17.6 7.0 0.0064 16.1 4.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CAR23233.1 - 0.0036 16.9 4.4 0.0036 16.9 3.1 2.3 2 0 0 2 2 2 1 PHD-finger zf-Apc11 PF12861.2 CAR23233.1 - 0.014 15.1 0.7 0.034 13.9 0.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CAR23233.1 - 0.039 14.0 2.1 0.099 12.7 1.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 CAR23233.1 - 0.26 10.8 4.3 1.1 8.8 2.9 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.20 CAR23234.1 - 1.5e-66 224.2 0.2 9.7e-65 218.2 0.2 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23234.1 - 2.9e-50 170.7 0.1 1.8e-48 164.8 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CAR23234.1 - 4.8e-34 116.4 2.0 6.6e-34 116.0 0.1 2.3 3 0 0 3 3 3 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 CAR23234.1 - 3.3e-10 39.9 0.1 1.2e-09 38.2 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CAR23234.1 - 4.2e-10 39.3 1.6 7.3e-10 38.5 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CAR23234.1 - 3.6e-05 22.8 0.1 0.00028 19.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Atg14 PF10186.4 CAR23235.1 - 4e-05 22.7 3.8 0.00011 21.2 2.6 1.6 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Zip PF02535.17 CAR23236.1 - 7.7e-45 153.2 18.6 1.2e-40 139.5 5.0 3.1 3 1 0 3 3 3 2 ZIP Zinc transporter MFS_1 PF07690.11 CAR23237.1 - 1.6e-28 99.4 55.9 2.4e-25 89.0 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR23237.1 - 4.2e-06 25.6 40.4 0.00013 20.7 7.5 4.1 3 1 1 4 4 4 4 Sugar (and other) transporter MFS_1_like PF12832.2 CAR23237.1 - 0.00057 19.6 4.6 0.0031 17.2 0.1 3.2 3 0 0 3 3 3 1 MFS_1 like family DUF2684 PF10885.3 CAR23237.1 - 0.08 12.8 2.1 0.24 11.2 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) CBM_48 PF02922.13 CAR23238.1 - 0.011 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3843 PF12954.2 CAR23238.1 - 0.091 11.7 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) DUF2028 PF09667.5 CAR23238.1 - 0.16 12.1 1.1 0.25 11.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) STAG PF08514.6 CAR23239.1 - 1.3e-12 47.4 4.5 1.9e-12 46.9 2.0 2.2 2 0 0 2 2 2 1 STAG domain HEAT PF02985.17 CAR23239.1 - 0.00076 19.3 0.2 2.5 8.3 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 CAR23239.1 - 0.003 17.7 0.0 0.12 12.6 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats Nipped-B_C PF12830.2 CAR23239.1 - 0.082 12.5 0.1 0.082 12.5 0.1 3.7 2 1 2 4 4 4 0 Sister chromatid cohesion C-terminus Pilus_CpaD PF09476.5 CAR23239.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) MMgT PF10270.4 CAR23240.1 - 7.6e-19 68.1 0.0 9.2e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter APC_CDC26 PF10471.4 CAR23241.1 - 2.8e-21 76.0 1.0 3.3e-21 75.8 0.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 HAUS-augmin3 PF14932.1 CAR23241.1 - 0.062 12.4 0.4 0.069 12.3 0.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 RINGv PF12906.2 CAR23242.1 - 3e-15 55.9 5.3 5.4e-15 55.1 3.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CAR23242.1 - 0.071 12.9 5.0 0.14 12.0 3.5 1.5 1 0 0 1 1 1 0 Ring finger domain Peptidase_C48 PF02902.14 CAR23243.1 - 4.1e-39 134.4 2.8 7.9e-39 133.5 2.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Tim44 PF04280.10 CAR23244.1 - 4.2e-31 107.9 0.0 9e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain DUF1770 PF08589.5 CAR23245.1 - 0.15 12.6 0.4 0.26 11.9 0.3 1.4 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) RNA_pol_A_bac PF01000.21 CAR23246.1 - 2.6e-32 111.2 0.1 6.4e-32 110.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CAR23246.1 - 1.2e-15 56.4 0.0 1.8e-15 55.7 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.16 CAR23247.1 - 6.9e-26 90.9 0.0 8.7e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 CAR23247.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase BtpA PF03437.10 CAR23247.1 - 0.16 11.1 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 BtpA family DUF4602 PF15375.1 CAR23248.1 - 0.01 15.8 1.3 0.01 15.8 0.9 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4602) CDC45 PF02724.9 CAR23248.1 - 1.1 7.2 9.3 1.7 6.6 6.5 1.4 1 0 0 1 1 1 0 CDC45-like protein HLH PF00010.21 CAR23249.1 - 1.7e-14 53.2 0.2 3.6e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lactamase_B_3 PF13483.1 CAR23249.1 - 0.0043 16.7 0.3 0.0087 15.7 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UCR_hinge PF02320.11 CAR23250.1 - 7.2e-26 89.9 4.4 1.2e-25 89.2 3.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Mitofilin PF09731.4 CAR23250.1 - 1.6 7.2 17.1 2 7.0 11.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Adaptin_binding PF10199.4 CAR23250.1 - 1.9 8.8 20.9 2.9 8.1 14.5 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Raftlin PF15250.1 CAR23250.1 - 1.9 6.8 6.8 2.3 6.6 4.7 1.1 1 0 0 1 1 1 0 Raftlin SAPS PF04499.10 CAR23250.1 - 2.1 6.9 13.5 2.3 6.7 9.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Cwf_Cwc_15 PF04889.7 CAR23250.1 - 2.3 7.8 29.0 3.1 7.4 20.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 CAR23250.1 - 2.3 6.0 41.3 2.6 5.8 28.6 1.0 1 0 0 1 1 1 0 Nop14-like family SPX PF03105.14 CAR23250.1 - 2.3 7.9 10.9 2.9 7.5 7.6 1.2 1 0 0 1 1 1 0 SPX domain CENP-T PF15511.1 CAR23250.1 - 3 7.0 23.5 3.7 6.6 16.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 CAR23250.1 - 3.8 6.4 33.7 4.7 6.1 23.4 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.7 CAR23250.1 - 3.9 5.7 32.9 4.9 5.4 22.8 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF2201_N PF13203.1 CAR23250.1 - 4.4 6.3 12.7 5.1 6.1 8.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 CAR23250.1 - 4.7 6.5 28.6 6.5 6.0 19.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ribosomal_L29e PF01779.12 CAR23251.1 - 4.2e-25 87.3 8.5 6.1e-25 86.8 5.9 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_6 PF14259.1 CAR23252.1 - 8.6e-19 67.2 0.0 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR23252.1 - 6.1e-16 57.8 0.1 1.3e-10 40.7 0.0 3.2 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR23252.1 - 7.2e-07 28.9 0.0 8.8e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.13 CAR23253.1 - 2.8e-41 140.3 2.7 4.4e-41 139.7 1.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CAR23253.1 - 2e-13 50.1 0.1 4.9e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SMC_N PF02463.14 CAR23254.1 - 7.6e-72 241.1 2.2 6.2e-71 238.1 1.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAR23254.1 - 5.5e-22 77.9 0.3 2e-21 76.1 0.1 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CAR23254.1 - 1.1e-14 55.3 19.7 1.1e-14 55.3 13.7 6.2 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 CAR23254.1 - 9.3e-09 35.6 30.0 0.00029 20.8 6.5 4.8 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 CAR23254.1 - 2.5e-05 23.7 0.0 6.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 CAR23254.1 - 0.0004 18.9 20.6 0.0004 18.9 14.3 5.4 3 2 2 5 5 5 2 AAA domain IncA PF04156.9 CAR23254.1 - 0.0022 17.5 3.8 0.0022 17.5 2.6 7.9 3 2 3 6 6 6 1 IncA protein HsbA PF12296.3 CAR23254.1 - 0.0051 16.6 1.4 0.0051 16.6 1.0 4.7 4 1 2 6 6 6 1 Hydrophobic surface binding protein A ABC_tran PF00005.22 CAR23254.1 - 0.014 15.6 0.7 0.1 12.8 0.1 5.4 3 2 1 4 4 4 0 ABC transporter DUF1664 PF07889.7 CAR23254.1 - 1.8 8.3 53.8 0.84 9.4 1.5 8.0 4 2 4 8 8 8 0 Protein of unknown function (DUF1664) FAD_binding_1 PF00667.15 CAR23255.1 - 7.2e-63 211.9 0.0 1.3e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CAR23255.1 - 5.5e-10 39.7 0.0 2.1e-09 37.8 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PPP4R2 PF09184.6 CAR23256.1 - 0.083 12.4 7.8 0.15 11.5 5.4 1.3 1 0 0 1 1 1 0 PPP4R2 Arm PF00514.18 CAR23256.1 - 0.99 9.3 7.7 6.7 6.7 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat BAG PF02179.11 CAR23257.1 - 2.1e-13 50.1 5.7 3.6e-13 49.4 3.9 1.5 1 0 0 1 1 1 1 BAG domain DUF4259 PF14078.1 CAR23257.1 - 0.024 15.1 0.1 0.16 12.4 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) CDC37_N PF03234.9 CAR23257.1 - 0.059 13.6 7.3 0.079 13.2 5.1 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Lum_binding PF00677.12 CAR23258.1 - 5.8e-51 170.3 3.0 6.5e-25 86.8 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain DUF1269 PF06897.7 CAR23258.1 - 0.045 13.7 0.3 0.14 12.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) WD40 PF00400.27 CAR23259.1 - 1.5e-12 46.8 6.0 0.00017 21.3 0.1 6.9 8 0 0 8 8 8 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CAR23259.1 - 5e-05 22.7 0.0 0.024 14.1 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.1 CAR23259.1 - 0.00062 19.3 0.0 0.0067 15.9 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain Lactonase PF10282.4 CAR23259.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Cut8_C PF08559.5 CAR23260.1 - 7.4e-42 142.5 0.0 1.1e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 CAR23260.1 - 1.2e-11 44.1 4.6 3.2e-11 42.8 3.2 1.8 1 0 0 1 1 1 1 Cut8 dimerisation domain DUF1689 PF07954.6 CAR23261.1 - 0.064 13.1 0.1 0.096 12.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) Sedlin_N PF04628.8 CAR23263.1 - 1.8e-48 163.7 0.0 2e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CAR23263.1 - 2.1e-05 24.2 0.1 3.8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Sybindin-like family MIS13 PF08202.6 CAR23264.1 - 1.6e-69 234.2 21.5 1.6e-69 234.2 14.9 1.8 2 0 0 2 2 2 1 Mis12-Mtw1 protein family SOCS_box PF07525.11 CAR23264.1 - 0.016 15.0 0.1 0.05 13.4 0.1 1.8 1 0 0 1 1 1 0 SOCS box Med22 PF06179.7 CAR23265.1 - 1.8e-18 66.5 1.8 2.4e-18 66.1 1.3 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex SOG2 PF10428.4 CAR23265.1 - 0.05 12.2 1.1 0.062 11.9 0.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein dUTPase PF00692.14 CAR23266.1 - 1.1e-40 138.1 0.0 1.2e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 dUTPase Acetyltransf_7 PF13508.1 CAR23267.1 - 4.7e-06 26.6 0.0 8.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR23267.1 - 0.00015 21.7 0.2 0.00057 19.8 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CAR23267.1 - 0.013 15.3 0.1 0.042 13.7 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR23267.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 CAR23267.1 - 0.11 12.6 0.0 0.89 9.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_M16 PF00675.15 CAR23268.1 - 1.4e-31 109.2 0.1 3.8e-31 107.8 0.1 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR23268.1 - 1.4e-17 63.9 0.0 1.9e-07 30.9 0.0 4.1 4 0 0 4 4 4 3 Peptidase M16 inactive domain DotA PF11388.3 CAR23269.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Cyclin_N PF00134.18 CAR23270.1 - 1.1e-40 138.1 0.3 2.3e-40 137.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR23270.1 - 1.5e-22 79.7 0.5 6e-22 77.7 0.0 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain ApoO PF09769.4 CAR23270.1 - 0.043 13.5 0.1 0.083 12.5 0.0 1.6 1 1 0 1 1 1 0 Apolipoprotein O U79_P34 PF03064.11 CAR23270.1 - 0.18 11.3 8.3 0.26 10.7 5.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Cyclin_N PF00134.18 CAR23271.1 - 1e-40 138.2 0.3 7.5e-40 135.4 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR23271.1 - 4.3e-30 104.0 0.1 2e-29 101.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain IF-2B PF01008.12 CAR23272.1 - 8.7e-82 274.2 0.0 1e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ATP-synt_S1 PF05827.7 CAR23273.1 - 1.2e-05 24.8 0.0 0.0073 15.6 0.0 2.1 1 1 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) VMA21 PF09446.5 CAR23274.1 - 1.2e-16 60.3 8.8 1.5e-16 60.0 6.1 1.1 1 0 0 1 1 1 1 VMA21-like domain MARVEL PF01284.18 CAR23274.1 - 0.017 14.9 1.4 0.017 14.9 0.9 1.0 1 0 0 1 1 1 0 Membrane-associating domain DUF1469 PF07332.6 CAR23274.1 - 0.027 14.1 2.2 0.031 13.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Med18 PF09637.5 CAR23275.1 - 1.8e-63 214.3 0.0 2.3e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Med18 protein Pescadillo_N PF06732.6 CAR23276.1 - 2.7e-123 410.7 0.7 2.7e-123 410.7 0.5 2.3 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CAR23276.1 - 7.6e-11 42.0 0.0 4.4e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rhomboid PF01694.17 CAR23278.1 - 2.4e-30 105.4 14.9 2.4e-30 105.4 10.4 1.6 2 0 0 2 2 2 1 Rhomboid family RabGAP-TBC PF00566.13 CAR23279.1 - 5.5e-52 176.3 0.1 1.4e-51 175.0 0.1 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CAR23279.1 - 5.7e-14 51.3 0.0 1.4e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 CAR23279.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Fmp27_WPPW PF10359.4 CAR23280.1 - 4.2e-106 355.1 1.9 6e-106 354.6 0.4 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CAR23280.1 - 2.8e-100 336.3 1.1 6.8e-100 335.0 0.8 1.7 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CAR23280.1 - 1.5e-48 164.6 0.1 6.9e-48 162.5 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CAR23280.1 - 4.3e-30 104.5 1.7 6.2e-30 104.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CAR23280.1 - 3.2e-14 53.2 0.1 2.3e-13 50.4 0.1 2.7 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Telomere_reg-2 PF10193.4 CAR23281.1 - 2.8e-23 82.3 1.4 2.8e-23 82.3 1.0 3.7 4 0 0 4 4 4 2 Telomere length regulation protein DUF1644 PF07800.7 CAR23281.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Peptidase_C50 PF03568.12 CAR23282.1 - 5.5e-121 403.8 0.1 1.1e-120 402.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 CAR23282.1 - 0.022 13.9 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 CHAT domain Flavin_Reduct PF01613.13 CAR23284.1 - 2.4e-29 102.1 0.0 2.9e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PH PF00169.24 CAR23285.1 - 6.7e-13 48.7 0.9 1.6e-12 47.4 0.6 1.7 1 0 0 1 1 1 1 PH domain TRAM_LAG1_CLN8 PF03798.11 CAR23286.1 - 6.5e-29 100.8 14.0 1.1e-28 100.1 9.7 1.4 1 0 0 1 1 1 1 TLC domain ADH_zinc_N PF00107.21 CAR23287.1 - 5e-31 106.9 1.1 7.5e-31 106.3 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR23287.1 - 5.9e-29 100.0 0.3 1.2e-28 99.0 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CAR23287.1 - 5e-06 27.4 0.1 1.3e-05 26.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2284 PF10050.4 CAR23287.1 - 0.12 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) CDP-OH_P_transf PF01066.16 CAR23288.1 - 3.7e-20 72.1 2.9 3.7e-20 72.1 2.0 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribosomal_L7Ae PF01248.21 CAR23289.1 - 5.5e-23 80.3 0.3 8.7e-23 79.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CAR23289.1 - 0.0015 18.3 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.11 CAR23290.1 - 4.5e-71 238.5 1.9 8.2e-71 237.7 1.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CAR23290.1 - 1.7e-43 148.7 0.0 7.4e-36 123.7 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 CAR23291.1 - 1.4e-67 227.5 3.0 1.8e-67 227.1 2.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein PrgI PF12666.2 CAR23291.1 - 4.6 7.4 5.9 0.67 10.1 0.7 2.1 2 1 0 2 2 2 0 PrgI family protein V-SNARE_C PF12352.3 CAR23292.1 - 4.3e-17 61.9 1.3 4.3e-17 61.9 0.9 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.6 CAR23292.1 - 0.041 11.4 9.5 0.052 11.0 6.6 1.1 1 0 0 1 1 1 0 Prominin DUF2433 PF10360.4 CAR23292.1 - 0.18 12.1 2.0 0.3 11.3 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) Peptidase_C6 PF00851.13 CAR23292.1 - 2.2 6.7 8.1 0.41 9.2 1.4 1.9 1 1 1 2 2 2 0 Helper component proteinase BLOC1_2 PF10046.4 CAR23292.1 - 4.3 7.5 9.4 1.6 8.9 1.8 2.8 1 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Autophagy_act_C PF03987.10 CAR23293.1 - 5.4e-07 29.7 0.1 1.2e-05 25.4 0.1 2.7 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Fer2_3 PF13085.1 CAR23294.1 - 8.8e-31 105.9 0.1 1.4e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CAR23294.1 - 1.9e-10 40.9 7.6 1.9e-10 40.9 5.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CAR23294.1 - 7.4e-09 35.5 5.7 7.4e-09 35.5 3.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CAR23294.1 - 1.5e-05 25.3 2.0 1.5e-05 25.3 1.4 2.7 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CAR23294.1 - 0.0002 21.5 6.5 0.034 14.4 0.6 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CAR23294.1 - 0.00027 20.6 5.6 0.00027 20.6 3.9 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CAR23294.1 - 0.0042 17.4 5.7 0.0042 17.4 4.0 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CAR23294.1 - 0.0054 16.4 1.3 0.0054 16.4 0.9 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 CAR23294.1 - 6.8 7.3 8.4 1.8 9.1 0.2 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF1162 PF06650.7 CAR23295.1 - 3.5e-80 269.1 0.4 5.4e-79 265.2 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CAR23295.1 - 2.5e-40 136.6 0.1 1e-39 134.7 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Fungal_trans PF04082.13 CAR23296.1 - 6.3e-18 64.5 3.0 1.7e-17 63.1 1.9 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR23296.1 - 2.2e-09 37.0 13.0 2.2e-09 37.0 9.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 CAR23297.1 - 3.7e-63 213.0 14.6 3.7e-63 213.0 10.1 1.4 2 0 0 2 2 2 1 RTA1 like protein MENTAL PF10457.4 CAR23297.1 - 0.016 14.8 2.0 0.016 14.8 1.4 3.0 3 1 1 4 4 4 0 Cholesterol-capturing domain Ecm29 PF13001.2 CAR23298.1 - 1.2e-130 436.3 1.1 2.9e-130 435.0 0.2 2.2 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 CAR23298.1 - 2.9e-11 42.4 0.6 0.057 13.5 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CAR23298.1 - 1.1e-05 25.7 0.0 0.00083 19.6 0.0 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CAR23298.1 - 0.005 17.2 1.5 17 6.0 0.0 5.1 5 1 1 6 6 6 2 HEAT-like repeat ubiquitin PF00240.18 CAR23299.1 - 2.9e-135 439.8 23.5 1.8e-33 113.7 0.6 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 CAR23299.1 - 1.3e-77 255.4 21.1 6.9e-19 67.3 0.5 4.2 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR23299.1 - 4.9e-23 81.2 13.1 0.00022 21.4 0.2 5.9 4 4 1 5 5 5 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CAR23299.1 - 2.8e-21 75.8 0.8 0.0016 18.1 0.0 4.2 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CAR23299.1 - 2.3e-13 49.9 2.8 0.15 11.9 0.0 4.8 4 3 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAR23299.1 - 5.8e-13 48.8 3.4 0.21 11.7 0.0 4.4 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CAR23299.1 - 3.6e-10 39.7 0.1 2.2 8.3 0.0 5.1 5 0 0 5 5 5 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 CAR23299.1 - 8.7e-06 25.5 5.8 7 6.6 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 CAR23299.1 - 1.8e-05 23.9 0.5 3.1 6.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 CAR23299.1 - 0.0002 21.0 4.9 20 4.9 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 CAR23299.1 - 0.0013 17.1 14.6 3.6 5.8 0.2 5.4 5 3 0 5 5 5 4 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 CAR23299.1 - 0.0035 16.8 0.1 70 2.7 0.0 4.0 3 1 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 CAR23299.1 - 0.0085 16.4 1.0 1.3e+02 3.0 0.0 4.2 4 0 0 4 4 4 0 ACT domain Brix PF04427.13 CAR23299.1 - 0.029 14.0 0.5 24 4.5 0.0 3.8 1 1 1 4 4 4 0 Brix domain BsuBI_PstI_RE PF06616.6 CAR23299.1 - 0.079 11.7 0.4 4.1 6.1 0.0 3.2 4 0 0 4 4 4 0 BsuBI/PstI restriction endonuclease C-terminus Tash_PEST PF07708.6 CAR23299.1 - 0.098 12.6 29.1 4.9 7.2 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 CAR23299.1 - 0.2 11.6 7.8 70 3.5 0.1 4.1 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 CAR23299.1 - 0.45 10.6 12.2 64 3.7 0.1 5.7 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 CAR23299.1 - 1.5 8.8 7.4 1.5e+02 2.4 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) ENTH PF01417.15 CAR23300.1 - 5.8e-32 110.1 0.8 7.7e-32 109.7 0.6 1.2 1 0 0 1 1 1 1 ENTH domain SAP18 PF06487.7 CAR23300.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.7 1 1 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Prp19 PF08606.6 CAR23301.1 - 7.1e-29 99.3 1.9 1.7e-28 98.0 1.3 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like RabGAP-TBC PF00566.13 CAR23302.1 - 0.00058 19.3 7.4 0.0073 15.8 0.1 3.6 3 1 0 4 4 4 2 Rab-GTPase-TBC domain SKG6 PF08693.5 CAR23303.1 - 0.00069 18.8 3.7 0.0039 16.4 2.6 2.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain FixQ PF05545.6 CAR23303.1 - 0.15 11.7 0.2 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ zf-C2H2 PF00096.21 CAR23304.1 - 3.3e-05 23.9 23.0 4.4e-05 23.5 1.4 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR23304.1 - 0.00096 19.3 10.1 0.0023 18.1 2.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR23304.1 - 0.0056 16.9 0.7 0.0056 16.9 0.5 3.9 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 CAR23304.1 - 0.03 14.5 1.5 0.082 13.1 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR23304.1 - 0.13 12.4 0.8 0.3 11.2 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MobB PF03205.9 CAR23305.1 - 9.6e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 CAR23305.1 - 0.00022 21.0 0.0 0.00054 19.7 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 FtsK_SpoIIIE PF01580.13 CAR23305.1 - 0.0005 19.5 0.0 0.0008 18.9 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 CAR23305.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CAR23305.1 - 0.062 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 CAR23305.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 CAR23305.1 - 0.076 13.8 0.0 0.23 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 CAR23305.1 - 0.079 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.18 CAR23305.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 CAR23306.1 - 6.6e-94 311.0 0.6 1.1e-46 158.3 0.0 3.7 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR23306.1 - 1.3e-14 53.8 0.0 1.4e-07 30.7 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CAR23306.1 - 2.7e-12 47.0 0.5 0.00021 21.3 0.0 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CAR23306.1 - 5.3e-12 46.6 0.3 1.3e-06 29.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 CAR23306.1 - 1.2e-10 40.7 0.0 0.00053 19.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 CAR23306.1 - 1.4e-10 41.4 0.0 0.0062 16.6 0.0 4.8 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.9 CAR23306.1 - 1.9e-10 40.8 0.0 0.00065 19.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CAR23306.1 - 2.7e-10 40.2 0.0 0.0019 18.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 CAR23306.1 - 4.3e-10 39.6 0.0 0.00023 21.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CAR23306.1 - 1.5e-09 37.6 0.1 0.0016 18.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CAR23306.1 - 6.2e-09 36.2 1.4 0.00018 21.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain TIP49 PF06068.8 CAR23306.1 - 7.4e-09 34.8 0.0 0.00027 19.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus ABC_tran PF00005.22 CAR23306.1 - 9.1e-08 32.4 0.1 0.0094 16.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter Vps4_C PF09336.5 CAR23306.1 - 1.5e-07 31.2 3.5 1.4e-05 24.9 0.1 3.5 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 CAR23306.1 - 1.9e-07 31.1 0.0 0.014 15.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 CAR23306.1 - 5.8e-07 29.0 0.2 0.022 14.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CAR23306.1 - 7.2e-07 28.8 0.4 0.056 13.2 0.1 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 CAR23306.1 - 1.2e-06 28.5 0.3 0.03 14.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 CAR23306.1 - 3.5e-06 26.3 0.3 0.042 12.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CAR23306.1 - 3.9e-06 26.3 3.3 1.8 7.9 0.0 4.6 2 2 2 4 4 4 2 AAA domain AAA_3 PF07726.6 CAR23306.1 - 5.6e-06 26.0 0.0 0.048 13.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 CAR23306.1 - 1.3e-05 25.1 0.3 0.0028 17.5 0.0 3.3 3 1 0 3 3 3 1 Cytidylate kinase-like family NACHT PF05729.7 CAR23306.1 - 1.4e-05 24.8 0.1 0.51 9.9 0.0 3.5 3 0 0 3 3 3 2 NACHT domain SKI PF01202.17 CAR23306.1 - 1.7e-05 24.7 1.7 0.079 12.8 0.0 3.5 3 1 0 3 3 3 2 Shikimate kinase Rad17 PF03215.10 CAR23306.1 - 4.2e-05 22.4 0.3 0.035 12.7 0.0 2.9 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 CAR23306.1 - 0.00012 22.0 0.0 0.65 10.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 CAR23306.1 - 0.00014 21.4 0.0 0.23 10.9 0.0 3.2 2 1 0 3 3 3 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CAR23306.1 - 0.00016 21.4 2.7 2.5 7.7 0.0 4.6 4 3 1 5 5 4 1 Archaeal ATPase DUF815 PF05673.8 CAR23306.1 - 0.00023 20.1 0.1 0.13 11.1 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 CAR23306.1 - 0.00044 19.8 0.0 0.93 8.9 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CAR23306.1 - 0.0005 19.0 0.0 0.32 9.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain CPT PF07931.7 CAR23306.1 - 0.001 18.6 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 CAR23306.1 - 0.0014 17.8 0.0 1.4 8.0 0.0 3.2 2 1 0 3 3 3 1 KaiC SRPRB PF09439.5 CAR23306.1 - 0.0017 17.5 0.0 1.5 8.0 0.0 3.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Parvo_NS1 PF01057.12 CAR23306.1 - 0.0021 16.9 0.1 1.6 7.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CAR23306.1 - 0.0037 16.8 1.4 2.3 7.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.20 CAR23306.1 - 0.0041 16.6 0.0 1.8 7.9 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 CAR23306.1 - 0.0049 16.1 0.0 1.6 7.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.10 CAR23306.1 - 0.013 15.3 7.5 4.8 6.9 0.0 4.4 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 CAR23306.1 - 0.014 15.1 0.0 4.1 7.0 0.0 2.8 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 CAR23306.1 - 0.016 14.8 0.0 5.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 CAR23306.1 - 0.016 14.7 0.0 6.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AFG1_ATPase PF03969.11 CAR23306.1 - 0.018 13.8 0.2 7.6 5.2 0.0 3.1 3 0 0 3 3 3 0 AFG1-like ATPase MMR_HSR1 PF01926.18 CAR23306.1 - 0.04 13.8 0.2 2.8 7.9 0.0 3.3 3 1 0 3 3 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 CAR23306.1 - 0.051 12.7 0.3 0.91 8.6 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 CAR23306.1 - 0.077 12.2 1.4 2 7.6 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_11 PF13086.1 CAR23306.1 - 0.078 12.5 9.7 1.2 8.6 0.0 3.8 4 1 0 4 4 2 0 AAA domain AAA_31 PF13614.1 CAR23306.1 - 0.08 12.8 0.0 1.9 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CAR23306.1 - 0.092 12.2 0.0 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CAR23306.1 - 2.2 8.5 0.0 2.2 8.5 0.0 4.0 4 1 0 4 4 2 0 AAA domain KH_1 PF00013.24 CAR23308.1 - 2.3e-16 59.1 3.0 1.7e-07 30.8 0.0 4.9 6 0 0 6 6 6 3 KH domain KH_3 PF13014.1 CAR23308.1 - 1e-10 40.9 1.1 0.00053 19.5 0.0 4.4 4 0 0 4 4 4 2 KH domain DUF2623 PF11115.3 CAR23308.1 - 0.074 13.0 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) GrpB PF04229.9 CAR23309.1 - 0.052 13.2 1.4 0.093 12.4 1.0 1.4 1 0 0 1 1 1 0 GrpB protein Phosphodiest PF01663.17 CAR23310.1 - 3.4e-11 43.0 0.4 6.6e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CAR23310.1 - 0.0028 17.0 0.3 0.0051 16.2 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CAR23310.1 - 0.0033 16.6 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Zn_clus PF00172.13 CAR23311.1 - 1.6e-09 37.4 10.7 3e-09 36.6 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CAR23312.1 - 8.3e-34 116.8 26.9 8.3e-34 116.8 18.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR23312.1 - 1.7e-10 40.0 10.2 1.7e-10 40.0 7.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CAR23312.1 - 4.2e-08 31.8 3.7 7.3e-08 31.0 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M24 PF00557.19 CAR23313.1 - 2.3e-38 131.8 0.0 5.3e-38 130.6 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CAR23313.1 - 3.5e-13 50.1 0.0 1e-11 45.4 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Fe-S_biosyn PF01521.15 CAR23314.1 - 3.2e-17 62.4 0.0 7.1e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis LCD1 PF09798.4 CAR23314.1 - 0.61 8.0 2.9 0.92 7.4 2.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein AAA_2 PF07724.9 CAR23315.1 - 1e-47 162.2 0.0 2.4e-46 157.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CAR23315.1 - 1.5e-24 85.6 0.5 7.2e-24 83.5 0.3 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CAR23315.1 - 4.4e-24 85.1 0.1 3.1e-14 53.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAR23315.1 - 7.3e-17 61.3 0.0 3.3e-09 36.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 CAR23315.1 - 3.1e-15 55.8 3.6 5.9e-10 38.9 0.1 3.5 3 1 0 3 3 2 2 Clp amino terminal domain Sigma54_activat PF00158.21 CAR23315.1 - 3.4e-12 46.1 0.0 1.3e-08 34.5 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 CAR23315.1 - 1.8e-10 41.1 10.2 0.00027 20.9 0.0 5.2 5 2 1 7 7 7 2 AAA ATPase domain AAA_22 PF13401.1 CAR23315.1 - 4.6e-10 39.7 0.4 0.00052 20.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 CAR23315.1 - 2.4e-05 24.1 0.9 0.98 9.0 0.0 4.3 3 1 1 4 4 4 2 Archaeal ATPase TIP49 PF06068.8 CAR23315.1 - 6.1e-05 21.8 2.7 0.17 10.5 0.0 3.6 4 0 0 4 4 4 2 TIP49 C-terminus AAA_19 PF13245.1 CAR23315.1 - 0.00018 21.1 0.0 0.5 10.1 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 CAR23315.1 - 0.00022 20.4 0.0 0.14 11.3 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CAR23315.1 - 0.00026 21.7 5.7 0.11 13.2 0.0 4.0 4 1 0 4 4 3 2 AAA domain NACHT PF05729.7 CAR23315.1 - 0.00031 20.4 0.0 0.74 9.4 0.0 3.1 3 0 0 3 3 3 2 NACHT domain AAA_3 PF07726.6 CAR23315.1 - 0.0005 19.6 0.0 1.3 8.6 0.0 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 CAR23315.1 - 0.0019 18.0 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 Torsin IstB_IS21 PF01695.12 CAR23315.1 - 0.0024 17.2 0.0 0.51 9.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CAR23315.1 - 0.0025 16.9 0.3 0.094 11.8 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 CAR23315.1 - 0.021 14.6 5.2 0.093 12.6 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.1 CAR23315.1 - 0.025 14.1 0.0 2 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CAR23315.1 - 0.045 13.4 0.0 8.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CAR23315.1 - 0.064 13.4 0.2 18 5.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_10 PF12846.2 CAR23315.1 - 0.095 12.1 2.1 1.4 8.2 0.0 3.5 4 0 0 4 4 4 0 AAA-like domain ABC_tran PF00005.22 CAR23315.1 - 0.7 10.1 6.3 5.2 7.3 0.0 4.2 4 0 0 4 4 4 0 ABC transporter APG6 PF04111.7 CAR23315.1 - 4.1 6.3 12.8 11 4.9 8.9 1.7 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CAR23315.1 - 7.2 4.3 8.0 12 3.6 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CAR23315.1 - 8.4 5.9 18.2 0.35 10.4 7.8 2.3 2 0 0 2 2 2 0 IncA protein RRM_1 PF00076.17 CAR23316.1 - 7e-27 92.8 1.6 2e-12 46.5 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR23316.1 - 5e-19 68.0 0.5 1.5e-07 31.2 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR23316.1 - 4.8e-17 61.5 0.3 1.1e-05 25.1 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR23316.1 - 0.00055 19.6 0.0 2 8.2 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif NPR3 PF03666.8 CAR23317.1 - 1.1e-152 508.7 1.9 1.1e-152 508.7 1.3 2.2 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Adenylsucc_synt PF00709.16 CAR23317.1 - 0.0056 15.3 0.0 0.0086 14.7 0.0 1.2 1 0 0 1 1 1 1 Adenylosuccinate synthetase EMP24_GP25L PF01105.19 CAR23318.1 - 6.7e-38 130.2 0.0 8.1e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1627 PF07789.7 CAR23318.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Metallophos PF00149.23 CAR23319.1 - 3.6e-44 150.5 0.1 4.4e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Yip1 PF04893.12 CAR23320.1 - 2.8e-07 30.2 5.3 3.8e-07 29.7 3.7 1.3 1 0 0 1 1 1 1 Yip1 domain Kelch_6 PF13964.1 CAR23321.1 - 2.7e-15 55.7 4.6 1.2e-07 31.6 0.0 5.5 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CAR23321.1 - 2e-12 46.6 1.3 3.7e-06 26.6 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CAR23321.1 - 4.3e-12 45.3 0.5 5.2e-06 25.9 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 CAR23321.1 - 6.7e-11 42.0 0.7 1.5e-05 25.0 0.0 5.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CAR23321.1 - 0.00041 20.0 3.2 0.021 14.5 0.1 3.9 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CAR23321.1 - 0.00073 19.4 0.3 0.15 12.0 0.0 3.7 4 0 0 4 4 4 1 Kelch motif DUF3554 PF12074.3 CAR23322.1 - 5.8e-44 150.8 22.8 9.8e-41 140.2 0.0 7.5 5 2 1 6 6 6 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 CAR23322.1 - 3e-38 129.9 26.1 2.6e-10 40.4 0.1 14.1 12 3 5 17 17 17 7 HEAT repeats HEAT PF02985.17 CAR23322.1 - 1.5e-30 102.4 30.8 0.0016 18.3 0.0 21.4 25 0 0 25 25 25 7 HEAT repeat HEAT_EZ PF13513.1 CAR23322.1 - 1.4e-27 95.4 32.4 0.0094 16.4 0.0 18.2 15 2 5 20 20 20 7 HEAT-like repeat CLASP_N PF12348.3 CAR23322.1 - 4.3e-14 52.4 0.3 2e-05 24.0 0.0 7.8 7 2 2 9 9 9 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 CAR23322.1 - 1.3e-10 41.5 9.3 2.5 8.5 0.0 10.4 9 3 3 12 12 12 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CAR23322.1 - 1.1e-05 25.3 17.2 4.4 7.1 0.0 10.3 10 2 2 13 13 13 3 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 CAR23322.1 - 3.9e-05 23.5 1.8 1.9 8.5 0.0 7.9 9 0 0 9 9 9 1 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 CAR23322.1 - 2 8.3 19.1 9 6.2 0.0 8.7 11 1 1 12 12 12 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 CAR23322.1 - 3.6 7.6 19.7 0.4 10.7 0.1 7.9 9 0 0 9 9 9 0 HEAT repeat associated with sister chromatid cohesion Hist_deacetyl PF00850.14 CAR23323.1 - 3.7e-81 272.8 0.0 4.8e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF1192 PF06698.6 CAR23323.1 - 0.044 13.5 1.3 0.08 12.7 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MT-A70 PF05063.9 CAR23324.1 - 1.4e-52 177.7 0.1 2.1e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 MT-A70 COX6A PF02046.10 CAR23325.1 - 2.8e-42 143.3 0.4 3e-42 143.2 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2741 PF10890.3 CAR23325.1 - 0.16 12.1 0.3 0.25 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) WD40 PF00400.27 CAR23326.1 - 3.9e-20 70.9 1.3 0.0006 19.6 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Ribosomal_S26e PF01283.14 CAR23327.1 - 1.3e-50 170.4 9.7 1.5e-50 170.1 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 CAR23327.1 - 0.016 14.0 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) Fer4_7 PF12838.2 CAR23327.1 - 0.036 14.4 0.8 0.26 11.6 0.3 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CAR23327.1 - 0.33 10.8 3.5 0.24 11.2 0.5 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain COX5B PF01215.14 CAR23328.1 - 3.8e-52 175.5 0.0 4.4e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Transp_cyt_pur PF02133.10 CAR23329.1 - 2.3e-15 56.0 28.7 2.3e-15 56.0 19.9 2.1 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.14 CAR23330.1 - 9.6e-30 103.0 0.0 1.4e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR23330.1 - 0.00035 20.0 0.0 0.0013 18.1 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CAR23330.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cys_Met_Meta_PP PF01053.15 CAR23331.1 - 8.8e-124 412.6 0.0 1e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CAR23331.1 - 0.0038 16.2 0.1 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.13 CAR23332.1 - 4.1e-10 39.3 9.9 4.1e-10 39.3 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CAR23332.1 - 6.7e-09 34.9 2.2 4.8e-08 32.1 0.4 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 CAR23333.1 - 1.9e-12 46.7 11.4 3.4e-06 27.0 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR23333.1 - 7.1e-11 41.6 9.1 3.9e-05 23.6 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR23333.1 - 3e-10 39.8 10.5 3.2e-07 30.3 1.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CAR23333.1 - 2.5e-08 33.8 7.9 0.00048 20.1 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR23333.1 - 1.5e-06 28.1 4.3 0.0078 16.3 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 CAR23333.1 - 0.0014 18.3 4.4 0.12 12.1 0.4 2.5 1 1 1 2 2 2 2 BED zinc finger zf-Di19 PF05605.7 CAR23333.1 - 0.0016 18.5 2.5 0.0027 17.8 1.7 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 CAR23333.1 - 0.05 13.2 5.8 0.93 9.2 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 CAR23333.1 - 0.057 13.5 4.8 3.5 7.8 0.3 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CAR23333.1 - 0.074 12.9 6.1 0.34 10.8 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.4 CAR23333.1 - 0.31 10.8 1.4 7.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain Elf1 PF05129.8 CAR23333.1 - 2.4 7.9 6.2 3.9 7.2 0.4 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Mnd1 PF03962.10 CAR23334.1 - 1e-46 158.9 5.9 1.2e-46 158.7 4.1 1.0 1 0 0 1 1 1 1 Mnd1 family NPV_P10 PF05531.7 CAR23334.1 - 0.0057 16.8 0.5 0.042 14.0 0.1 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Flg_bb_rod PF00460.15 CAR23334.1 - 0.071 12.8 0.3 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Flagella basal body rod protein Enkurin PF13864.1 CAR23334.1 - 0.093 12.9 4.7 5.6 7.2 0.1 2.3 1 1 1 2 2 2 0 Calmodulin-binding Lge1 PF11488.3 CAR23334.1 - 0.43 10.8 5.3 0.97 9.6 1.0 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 CHD5 PF04420.9 CAR23334.1 - 0.45 10.1 3.7 6 6.5 0.2 3.0 3 1 0 3 3 3 0 CHD5-like protein IncA PF04156.9 CAR23334.1 - 0.5 9.9 4.7 0.95 9.0 3.2 1.5 1 0 0 1 1 1 0 IncA protein ArfGap PF01412.13 CAR23335.1 - 1.9e-29 101.8 0.0 1.9e-29 101.8 0.0 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Med15 PF09606.5 CAR23335.1 - 0.058 11.5 57.5 0.074 11.2 39.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CAR23335.1 - 2.2 6.3 44.1 2.6 6.1 30.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3543 PF12063.3 CAR23336.1 - 1.8e-66 223.7 4.0 3.4e-65 219.5 2.8 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 CAR23336.1 - 5.4e-58 196.1 0.0 1.2e-57 195.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23336.1 - 3.7e-44 150.7 0.0 6e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.13 CAR23336.1 - 0.0031 17.3 2.6 0.046 13.5 0.0 2.8 2 2 0 2 2 2 1 MIT (microtubule interacting and transport) domain Kinase-like PF14531.1 CAR23336.1 - 0.0081 15.1 0.0 0.12 11.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.20 CAR23337.1 - 7.7e-54 182.5 0.0 1.3e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23337.1 - 1.2e-24 86.7 0.0 2.1e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23337.1 - 1.7e-05 23.9 0.0 3.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Vfa1 PF08432.5 CAR23338.1 - 4.8e-40 137.5 2.6 5.5e-40 137.3 1.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 CAR23338.1 - 0.048 13.3 1.7 0.07 12.8 1.1 1.2 1 0 0 1 1 1 0 FAM176 family MHC_II_alpha PF00993.15 CAR23338.1 - 0.07 12.7 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain Sas10_Utp3 PF04000.10 CAR23339.1 - 4.3e-09 36.4 0.1 7.8e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ribosomal_S8e PF01201.17 CAR23340.1 - 1.9e-39 134.8 7.7 9.7e-39 132.5 5.4 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 CAR23340.1 - 0.05 13.2 0.1 0.093 12.3 0.1 1.4 1 0 0 1 1 1 0 Homeo-prospero domain PUF PF00806.14 CAR23341.1 - 1.2e-54 178.7 31.9 3.5e-08 32.4 1.3 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HECT PF00632.20 CAR23343.1 - 9e-92 307.6 0.0 1.3e-91 307.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CAR23343.1 - 1.1e-34 117.8 20.5 1.3e-11 44.1 1.4 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CAR23343.1 - 8.9e-15 54.3 0.1 2.7e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 CAR23345.1 - 7.1e-29 100.7 0.0 9.5e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23345.1 - 8e-11 41.4 0.0 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MRG PF05712.8 CAR23346.1 - 1.3e-50 171.0 0.2 2.7e-50 169.9 0.0 1.5 1 1 1 2 2 2 1 MRG Tudor-knot PF11717.3 CAR23346.1 - 1.4e-08 34.2 0.1 3.5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF3347 PF11827.3 CAR23346.1 - 1.1 9.2 5.3 1.4 8.9 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Mito_carr PF00153.22 CAR23347.1 - 6.4e-74 243.7 0.1 1.1e-25 89.1 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_8 PF13833.1 CAR23347.1 - 0.029 13.9 0.3 0.73 9.4 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.1 CAR23347.1 - 1.8 8.7 15.0 0.39 10.8 0.2 5.5 5 1 1 6 6 6 0 EF-hand domain pair DUF4589 PF15252.1 CAR23348.1 - 0.022 14.6 0.3 0.022 14.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) Phasin_2 PF09361.5 CAR23348.1 - 0.053 13.5 0.2 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Phasin protein Bud13 PF09736.4 CAR23349.1 - 1.1e-24 87.3 11.2 1.1e-24 87.3 7.8 3.6 2 2 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex XRN_N PF03159.13 CAR23350.1 - 7.2e-100 333.2 5.0 7.8e-100 333.1 0.1 2.7 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus API5 PF05918.6 CAR23350.1 - 8.2 4.7 9.9 44 2.3 7.4 1.8 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Nucleoporin_FG PF13634.1 CAR23351.1 - 2.4e-41 140.5 165.2 1.8e-12 47.4 21.6 4.5 1 1 3 4 4 4 4 Nucleoporin FG repeat region DUF1664 PF07889.7 CAR23351.1 - 0.047 13.4 2.6 0.22 11.3 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 CAR23353.1 - 4.6e-45 153.7 0.0 3.8e-42 144.2 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23353.1 - 7e-14 51.5 0.0 7.8e-12 44.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR23353.1 - 0.13 11.2 0.0 0.47 9.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Myb_DNA-bind_4 PF13837.1 CAR23354.1 - 9.2e-07 28.9 0.0 4.7e-06 26.6 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CAR23354.1 - 0.014 15.2 0.2 0.028 14.3 0.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR23354.1 - 0.019 15.0 0.2 0.045 13.8 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CAR23354.1 - 0.039 14.5 0.1 0.073 13.7 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2838 PF10998.3 CAR23355.1 - 3.6e-41 139.5 15.5 3.6e-41 139.5 10.7 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Sec2p PF06428.6 CAR23355.1 - 0.074 12.9 0.8 0.3 10.9 0.1 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CCDC92 PF14916.1 CAR23355.1 - 0.14 11.7 1.5 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Val_tRNA-synt_C PF10458.4 CAR23355.1 - 0.17 11.9 1.9 0.25 11.4 0.2 1.9 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Pox_A_type_inc PF04508.7 CAR23355.1 - 0.34 10.8 7.0 0.34 10.8 0.1 3.7 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat PPR_2 PF13041.1 CAR23356.1 - 6.1e-12 45.3 0.8 3.2e-07 30.2 0.0 2.8 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 CAR23356.1 - 1.2e-07 31.2 4.1 0.00019 21.1 0.2 3.7 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 CAR23356.1 - 5e-06 26.3 4.5 0.097 13.0 0.0 5.5 6 0 0 6 6 6 2 Pentatricopeptide repeat domain TPR_12 PF13424.1 CAR23356.1 - 0.001 18.9 0.5 0.0093 15.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_1 PF12854.2 CAR23356.1 - 0.0016 17.8 0.0 0.074 12.5 0.1 2.6 2 0 0 2 2 2 1 PPR repeat HSV_VP16_C PF12149.3 CAR23356.1 - 0.0033 17.0 1.7 0.0092 15.6 1.2 1.8 1 0 0 1 1 1 1 Herpes simplex virus virion protein 16 C terminal Apc3 PF12895.2 CAR23356.1 - 0.067 13.3 1.0 0.59 10.3 0.5 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Cgr1 PF03879.9 CAR23357.1 - 2.7e-35 120.8 30.3 2.7e-35 120.8 21.0 1.3 1 1 0 1 1 1 1 Cgr1 family DUF342 PF03961.8 CAR23357.1 - 1.2 7.4 10.6 1.2 7.4 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 CAR23357.1 - 4.9 6.7 9.6 5.5 6.5 6.7 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CAR23357.1 - 9.6 5.1 14.0 9.5 5.1 9.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF706 PF05153.10 CAR23358.1 - 2.5e-122 407.0 6.3 3.1e-122 406.7 4.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 CAR23358.1 - 0.0065 16.4 0.7 0.7 9.9 0.0 2.8 3 1 0 3 3 3 2 HD domain DUF1796 PF08795.5 CAR23358.1 - 0.035 13.7 0.4 0.054 13.1 0.3 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Glyco_hydro_63 PF03200.11 CAR23360.1 - 4e-219 729.4 0.6 2.2e-218 727.0 0.4 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 CAR23360.1 - 6.7e-05 21.7 0.0 0.00011 21.0 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 CAR23360.1 - 0.021 13.4 0.2 0.049 12.2 0.1 1.5 1 1 0 1 1 1 0 Trehalase Rrn6 PF10214.4 CAR23361.1 - 4.4e-110 369.0 10.9 9.7e-110 367.8 7.5 1.5 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.15 CAR23362.1 - 1.4e-98 328.5 0.9 2.4e-98 327.8 0.6 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CAR23362.1 - 3.3e-45 154.6 3.7 9.6e-45 153.1 0.5 2.5 3 0 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 CAR23362.1 - 0.084 12.1 0.6 0.37 9.9 0.1 2.0 2 0 0 2 2 2 0 PcrB family Med3 PF11593.3 CAR23363.1 - 3.2e-49 168.1 45.3 1.1e-46 159.8 31.4 2.9 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal DUF1459 PF07312.6 CAR23363.1 - 0.99 9.3 6.1 0.52 10.2 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1459) Mo25 PF08569.6 CAR23364.1 - 0.04 12.9 0.0 0.13 11.2 0.0 1.8 2 1 0 2 2 2 0 Mo25-like Formyl_trans_N PF00551.14 CAR23365.1 - 5.7e-32 110.7 0.0 8.4e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Acyltransferase PF01553.16 CAR23366.1 - 8.2e-11 41.4 0.0 4.5e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase FYVE PF01363.16 CAR23367.1 - 1.3e-14 53.8 7.6 2.4e-14 52.9 5.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 CAR23367.1 - 2.6 7.9 13.8 5.9 6.8 9.6 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger STT3 PF02516.9 CAR23368.1 - 5.4e-137 457.6 37.8 8.9e-137 456.9 26.2 1.3 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit FEZ PF07763.8 CAR23369.1 - 0.0083 15.8 0.4 0.48 10.1 0.1 2.2 1 1 0 2 2 2 2 FEZ-like protein DUF3635 PF12330.3 CAR23370.1 - 5.1e-18 64.9 0.2 1.7e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 CAR23370.1 - 0.0022 17.1 0.0 0.005 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23370.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase CHD5 PF04420.9 CAR23371.1 - 1.6e-34 118.9 2.3 2e-34 118.5 1.6 1.1 1 0 0 1 1 1 1 CHD5-like protein Golgin_A5 PF09787.4 CAR23371.1 - 0.0051 15.3 1.3 0.0066 15.0 0.9 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 AAA_27 PF13514.1 CAR23371.1 - 0.04 11.6 2.0 0.048 11.3 1.4 1.0 1 0 0 1 1 1 0 AAA domain Med4 PF10018.4 CAR23371.1 - 0.047 13.0 4.0 0.062 12.6 2.8 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Hom_end_hint PF05203.11 CAR23371.1 - 0.077 12.7 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Prefoldin_2 PF01920.15 CAR23371.1 - 0.089 12.5 3.1 0.15 11.8 2.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit Myosin_tail_1 PF01576.14 CAR23371.1 - 0.13 9.9 3.6 0.17 9.5 2.5 1.0 1 0 0 1 1 1 0 Myosin tail FlxA PF14282.1 CAR23371.1 - 0.17 11.8 5.9 0.23 11.4 4.1 1.1 1 0 0 1 1 1 0 FlxA-like protein M_domain PF12938.2 CAR23371.1 - 0.46 10.2 2.6 0.61 9.8 1.8 1.1 1 0 0 1 1 1 0 M domain of GW182 CK_II_beta PF01214.13 CAR23372.1 - 5.8e-73 244.3 0.0 6.9e-73 244.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.8 CAR23373.1 - 1.6e-17 63.7 2.7 1.6e-17 63.7 1.9 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CAR23373.1 - 2.1e-10 40.1 0.0 4.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain POP1 PF06978.6 CAR23373.1 - 0.0061 16.2 1.3 0.009 15.6 0.9 1.4 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 IncA PF04156.9 CAR23373.1 - 0.07 12.7 0.0 0.07 12.7 0.0 2.0 1 1 1 2 2 2 0 IncA protein ATE_C PF04377.10 CAR23374.1 - 3.7e-41 140.1 0.1 6.7e-41 139.3 0.1 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CAR23374.1 - 2.3e-23 81.7 1.5 1.7e-22 79.0 1.5 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus PhnI PF05861.7 CAR23374.1 - 0.075 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Aminotran_1_2 PF00155.16 CAR23376.1 - 3.7e-19 68.9 0.0 5.2e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 CAR23377.1 - 2.4e-32 109.6 22.5 9.4e-10 38.0 0.0 8.3 8 1 0 8 8 8 5 WD domain, G-beta repeat Hira PF07569.6 CAR23377.1 - 4.6e-11 42.3 0.2 1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.5 CAR23377.1 - 7.2e-10 38.1 0.0 1.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 CAR23377.1 - 0.0048 16.6 0.1 0.58 9.8 0.0 3.4 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 CAR23377.1 - 0.07 13.4 1.7 8.1 6.8 0.0 3.6 2 1 1 3 3 3 0 PQQ-like domain RCC1_2 PF13540.1 CAR23377.1 - 0.13 11.8 0.2 0.38 10.4 0.1 1.8 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Aconitase PF00330.15 CAR23378.1 - 1.2e-190 633.9 0.0 1.5e-190 633.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAR23378.1 - 3.7e-45 153.2 0.0 7.5e-45 152.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 CAR23378.1 - 0.051 12.1 0.0 0.085 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) SHD1 PF03983.7 CAR23379.1 - 2.3e-34 116.8 0.1 4.3e-34 115.9 0.1 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 CAR23379.1 - 2.3e-33 113.3 7.4 4.6e-11 41.9 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 CAR23379.1 - 6.4e-33 112.0 7.1 2.9e-11 42.7 0.1 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 CAR23379.1 - 1.2e-27 95.1 0.3 7.7e-09 34.9 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF962 PF06127.6 CAR23380.1 - 1.4e-25 88.9 2.3 2e-25 88.4 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Proteasome PF00227.21 CAR23381.1 - 2.4e-43 147.6 0.0 3.3e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR23381.1 - 2e-15 55.7 0.1 3.3e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rsc14 PF08586.5 CAR23382.1 - 1.6e-28 99.1 0.1 2.7e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit zf-BED PF02892.10 CAR23382.1 - 0.021 14.5 0.5 0.051 13.3 0.3 1.6 1 0 0 1 1 1 0 BED zinc finger DUF900 PF05990.7 CAR23382.1 - 0.13 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) ERG4_ERG24 PF01222.12 CAR23383.1 - 6.7e-180 598.2 27.0 7.6e-180 598.0 18.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CytoC_RC PF02276.13 CAR23383.1 - 0.12 11.4 0.1 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Fungal_trans PF04082.13 CAR23384.1 - 2.6e-25 88.7 0.2 6.7e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR23384.1 - 1.3e-09 37.8 14.0 2.9e-09 36.6 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.14 CAR23385.1 - 1.5e-66 216.3 10.1 1.5e-09 36.8 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MIF4G PF02854.14 CAR23385.1 - 0.0091 15.4 0.4 0.39 10.1 0.1 2.7 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 CAR23385.1 - 0.011 15.4 0.5 0.04 13.6 0.2 2.0 1 1 0 1 1 1 0 MA3 domain Oxidored_FMN PF00724.15 CAR23386.1 - 2.2e-132 441.2 0.0 2.5e-132 441.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 CAR23387.1 - 9.7e-133 442.3 0.0 1.1e-132 442.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family E1-E2_ATPase PF00122.15 CAR23388.1 - 9.2e-64 214.6 5.6 9.2e-64 214.6 3.9 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CAR23388.1 - 4e-25 89.5 0.0 7.4e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR23388.1 - 1.1e-14 55.0 0.0 3.5e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAR23388.1 - 3.4e-12 45.6 0.0 8.2e-12 44.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR23388.1 - 0.00098 18.7 0.1 0.0026 17.3 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR23388.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2614 PF11023.3 CAR23388.1 - 1.4 8.7 5.1 0.53 10.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) ADH_N PF08240.7 CAR23389.1 - 6.2e-22 77.4 5.2 1.2e-21 76.5 3.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR23389.1 - 5.1e-15 55.1 0.0 1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CAR23389.1 - 0.0094 15.1 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CAR23389.1 - 0.042 13.4 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain tRNA_int_endo PF01974.12 CAR23390.1 - 7.5e-16 57.7 0.0 1.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain E1-E2_ATPase PF00122.15 CAR23391.1 - 2e-62 210.2 3.9 2e-62 210.2 2.7 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAR23391.1 - 1.2e-44 152.0 13.0 7.4e-44 149.4 6.0 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAR23391.1 - 2.1e-25 90.4 0.0 9.9e-25 88.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR23391.1 - 1.2e-16 60.3 0.0 3.2e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CAR23391.1 - 4e-12 46.7 0.0 1.6e-11 44.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAR23391.1 - 4.9e-12 45.1 0.1 2.1e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR23391.1 - 9.8e-05 22.0 1.3 0.00038 20.0 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2976 PF11190.3 CAR23391.1 - 0.024 14.1 0.0 0.024 14.1 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2976) COG5 PF10392.4 CAR23392.1 - 0.0009 19.2 5.0 0.0015 18.4 0.9 2.4 1 1 2 3 3 3 2 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 CAR23392.1 - 0.012 14.8 3.4 0.017 14.3 2.4 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CCDC144C PF14915.1 CAR23392.1 - 0.013 14.3 2.0 0.032 13.1 1.4 1.6 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF1664 PF07889.7 CAR23392.1 - 0.018 14.8 1.6 0.035 13.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 CAR23392.1 - 0.02 14.6 2.5 0.037 13.7 1.7 1.5 1 0 0 1 1 1 0 Laminin Domain II Fib_alpha PF08702.5 CAR23392.1 - 0.073 13.1 4.0 0.15 12.1 2.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Erp_C PF06780.6 CAR23392.1 - 0.14 12.0 7.0 0.12 12.2 3.4 2.0 1 1 1 2 2 2 0 Erp protein C-terminus DUF244 PF03112.9 CAR23392.1 - 0.26 10.8 5.5 0.44 10.0 1.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF AATF-Che1 PF13339.1 CAR23392.1 - 0.29 11.2 2.9 0.74 9.9 0.7 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor FlaC_arch PF05377.6 CAR23392.1 - 0.63 9.9 4.5 2.1 8.3 1.9 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 CAR23392.1 - 0.66 9.8 9.9 0.047 13.4 1.8 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.27 CAR23393.1 - 4.3e-20 70.7 5.7 7.4e-09 35.1 0.0 4.9 4 1 1 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 CAR23393.1 - 0.0024 17.5 0.0 0.0073 16.0 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Rep_fac-A_C PF08646.5 CAR23394.1 - 2.1e-55 186.4 1.2 3e-53 179.4 0.3 2.6 2 1 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CAR23394.1 - 1.9e-22 78.9 0.4 4.2e-11 42.5 0.0 4.6 4 0 0 4 4 4 4 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 CAR23394.1 - 0.00024 20.8 0.0 0.00048 19.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Fungal_trans PF04082.13 CAR23395.1 - 6.3e-09 35.0 0.1 1.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR23395.1 - 3.4e-05 23.6 8.6 8.4e-05 22.4 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FNIP_M PF14637.1 CAR23395.1 - 0.011 15.3 0.1 0.036 13.6 0.0 1.9 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain WD40 PF00400.27 CAR23396.1 - 8.9e-33 110.9 0.7 1.1e-06 28.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR23396.1 - 4.8e-06 26.4 0.1 0.0023 17.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CAR23397.1 - 9.7e-14 50.6 4.3 5.5e-07 29.2 0.7 5.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CAR23397.1 - 0.00078 17.8 0.0 0.0013 17.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 CAR23397.1 - 0.019 14.6 0.5 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF3299 PF11736.3 CAR23397.1 - 0.053 13.4 0.1 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) EMP24_GP25L PF01105.19 CAR23398.1 - 1.3e-52 178.1 1.5 1.5e-52 177.9 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SRR1 PF07985.7 CAR23398.1 - 0.01 15.7 0.1 6.3 6.8 0.0 2.4 2 0 0 2 2 2 0 SRR1 LMP PF04778.7 CAR23398.1 - 0.027 14.2 0.8 0.047 13.4 0.6 1.3 1 0 0 1 1 1 0 LMP repeated region Mt_ATP-synt_B PF05405.9 CAR23398.1 - 0.055 12.9 0.3 0.096 12.1 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) B-block_TFIIIC PF04182.7 CAR23400.1 - 5.8e-14 51.6 0.0 1.8e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC N6-adenineMlase PF10237.4 CAR23401.1 - 6.6e-55 185.1 0.1 1.4e-54 184.1 0.1 1.5 1 1 0 1 1 1 1 Probable N6-adenine methyltransferase IncA PF04156.9 CAR23401.1 - 0.94 9.0 5.5 1.3 8.5 3.8 1.2 1 0 0 1 1 1 0 IncA protein 3Beta_HSD PF01073.14 CAR23402.1 - 1e-85 286.8 0.0 1.2e-85 286.6 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CAR23402.1 - 2e-27 96.1 0.0 2.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CAR23402.1 - 9.7e-15 54.1 0.0 3.6e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CAR23402.1 - 6.1e-09 35.1 0.0 1.5e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CAR23402.1 - 2e-07 30.1 0.0 5.4e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CAR23402.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CAR23402.1 - 0.00051 20.0 0.0 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR23402.1 - 0.0019 17.8 0.0 0.012 15.2 0.0 2.1 2 1 0 2 2 2 1 KR domain Vps8 PF12816.2 CAR23403.1 - 2.3e-52 177.0 1.0 2.3e-52 177.0 0.7 1.8 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_5 PF14634.1 CAR23403.1 - 0.022 14.4 3.2 0.11 12.2 2.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR23403.1 - 0.023 14.6 1.1 0.13 12.2 0.8 2.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR23403.1 - 0.032 14.0 4.8 0.023 14.5 1.3 2.4 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 CAR23403.1 - 0.032 14.3 5.0 0.18 11.9 3.5 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger EF1_GNE PF00736.14 CAR23404.1 - 1.6e-30 104.6 1.8 3.3e-30 103.6 1.3 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CAR23404.1 - 2.4e-12 46.7 6.5 2.4e-12 46.7 4.5 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region DUF3752 PF12572.3 CAR23404.1 - 0.0095 16.0 1.6 0.013 15.5 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) GST_C_2 PF13410.1 CAR23404.1 - 0.06 13.2 0.1 0.58 10.0 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CAR23404.1 - 0.06 13.8 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SNF5 PF04855.7 CAR23405.1 - 4.6e-67 226.0 0.7 2e-40 138.8 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 PepX_N PF09168.5 CAR23405.1 - 0.15 12.2 0.6 4.8 7.3 0.0 2.4 1 1 0 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal dCMP_cyt_deam_1 PF00383.17 CAR23406.1 - 6.2e-10 38.6 0.4 1.1e-09 37.8 0.3 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Telomerase_RBD PF12009.3 CAR23407.1 - 3.7e-23 81.9 2.1 6.4e-23 81.1 0.4 2.3 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CAR23407.1 - 1.2e-08 34.5 0.7 4.6e-08 32.6 0.5 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AIP3 PF03915.8 CAR23408.1 - 2.2e-143 478.2 16.7 2.2e-143 478.2 11.6 2.3 2 0 0 2 2 2 1 Actin interacting protein 3 Parecho_VpG PF06344.6 CAR23408.1 - 0.12 12.2 0.5 0.25 11.3 0.3 1.5 1 0 0 1 1 1 0 Parechovirus Genome-linked protein HSBP1 PF06825.7 CAR23408.1 - 0.16 11.5 0.1 0.16 11.5 0.1 2.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 PMC2NT PF08066.7 CAR23408.1 - 0.39 11.0 6.2 0.41 10.9 1.9 3.0 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Syntaxin_2 PF14523.1 CAR23408.1 - 6.4 6.8 17.3 0.55 10.2 0.0 4.4 4 1 0 4 4 4 0 Syntaxin-like protein Mus7 PF09462.5 CAR23409.1 - 9.7e-29 100.6 10.5 1.7e-22 80.0 3.3 2.2 1 1 1 2 2 2 2 Mus7/MMS22 family Myb_DNA-bind_6 PF13921.1 CAR23410.1 - 0.0096 16.0 2.3 0.068 13.2 0.1 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain UPF0449 PF15136.1 CAR23410.1 - 1.9 8.7 12.8 2.9 8.1 0.1 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Cullin PF00888.17 CAR23411.1 - 3.1e-111 372.7 12.2 4e-111 372.4 8.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CAR23411.1 - 7.5e-18 64.1 0.0 2.7e-17 62.3 0.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_27 PF13463.1 CAR23411.1 - 0.1 12.9 0.0 0.46 10.8 0.0 2.1 2 1 0 2 2 2 0 Winged helix DNA-binding domain zf-CCCH PF00642.19 CAR23412.1 - 3.4e-09 36.1 2.8 3.4e-09 36.1 1.9 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 CAR23412.1 - 3.3e-07 29.8 7.0 3.3e-07 29.8 4.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR23412.1 - 1.4e-06 28.2 11.0 3.5e-06 26.9 7.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR23412.1 - 1.9e-06 27.4 11.5 1.9e-06 27.4 8.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAR23412.1 - 2.5e-06 27.0 11.8 6.5e-06 25.7 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR23412.1 - 1.8e-05 24.5 9.7 2.5e-05 24.0 5.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 CAR23412.1 - 0.019 14.8 8.8 0.019 14.8 6.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CAR23412.1 - 0.027 14.2 1.7 0.062 13.0 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CAR23412.1 - 0.037 13.7 5.4 0.14 11.9 3.8 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 CAR23412.1 - 0.26 10.8 8.1 0.64 9.5 5.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pex24p PF06398.6 CAR23413.1 - 1.8e-92 309.9 6.4 2.4e-92 309.5 4.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.13 CAR23414.1 - 5.3e-30 102.9 2.6 6e-30 102.8 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIIF_beta PF02270.10 CAR23415.1 - 5.3e-95 318.3 14.3 9.1e-95 317.5 9.9 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Adeno_E1B_19K PF01691.11 CAR23415.1 - 0.0068 15.6 0.1 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Adenovirus E1B 19K protein / small t-antigen Peptidase_S30 PF01577.11 CAR23415.1 - 0.049 13.0 7.1 0.11 11.9 4.9 1.5 1 0 0 1 1 1 0 Potyvirus P1 protease Prp18 PF02840.10 CAR23416.1 - 4.4e-44 149.8 0.6 1.4e-43 148.2 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain DUF4112 PF13430.1 CAR23417.1 - 1.4e-30 105.3 0.4 1.8e-30 104.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF4580 PF15162.1 CAR23417.1 - 0.033 13.5 0.1 0.048 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) CTP_transf_2 PF01467.21 CAR23418.1 - 7.4e-20 71.5 0.0 1.9e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CAR23418.1 - 0.025 14.2 2.0 13 5.3 0.1 3.2 3 0 0 3 3 3 0 FAD synthetase HABP4_PAI-RBP1 PF04774.10 CAR23419.1 - 0.00014 22.2 0.9 0.00016 22.1 0.6 1.3 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family RE_LlaJI PF09563.5 CAR23419.1 - 0.034 12.8 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 LlaJI restriction endonuclease CTP_transf_2 PF01467.21 CAR23420.1 - 1e-35 123.1 0.0 1.6e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Fungal_trans PF04082.13 CAR23421.1 - 5.9e-27 94.1 1.3 1e-26 93.4 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR23421.1 - 7.7e-07 28.9 9.0 1.3e-06 28.1 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Reprolysin PF01421.14 CAR23421.1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease PALP PF00291.20 CAR23422.1 - 1.1e-57 195.5 0.2 1.1e-57 195.5 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme AAA_19 PF13245.1 CAR23422.1 - 0.12 12.0 3.3 11 5.9 0.1 3.4 3 0 0 3 3 3 0 Part of AAA domain PWI PF01480.12 CAR23423.1 - 0.00053 20.0 0.3 0.0021 18.1 0.2 2.0 1 0 0 1 1 1 1 PWI domain LETM1 PF07766.8 CAR23423.1 - 0.008 15.2 1.3 0.027 13.4 0.2 2.3 2 0 0 2 2 2 1 LETM1-like protein PqqD PF05402.7 CAR23423.1 - 0.027 14.4 1.1 0.2 11.6 0.2 2.7 1 1 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF2217 PF10265.4 CAR23423.1 - 0.13 10.9 5.6 0.14 10.8 2.9 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Xpo1 PF08389.7 CAR23423.1 - 0.22 11.4 1.1 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Exportin 1-like protein DUF4600 PF15372.1 CAR23423.1 - 2.2 8.4 16.6 4.5 7.5 7.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) PspB PF06667.7 CAR23423.1 - 4.4 7.3 6.3 25 4.9 0.6 3.4 3 0 0 3 3 3 0 Phage shock protein B Polysacc_synt_C PF14667.1 CAR23424.1 - 0.19 11.5 1.3 0.37 10.5 0.4 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Abhydrolase_6 PF12697.2 CAR23425.1 - 1.4e-28 100.3 0.0 1.8e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR23425.1 - 7.3e-13 48.6 0.0 4.2e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR23425.1 - 9.3e-12 44.9 0.0 1.4e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CAR23425.1 - 1.8e-05 24.4 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 CAR23425.1 - 7.3e-05 23.1 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 CAR23425.1 - 0.00029 20.6 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 CAR23425.1 - 0.028 13.7 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_17 PF13207.1 CAR23425.1 - 0.034 14.9 0.1 0.08 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 CAR23425.1 - 0.078 12.8 0.1 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Torsin FSH1 PF03959.8 CAR23425.1 - 0.084 12.3 0.2 9.2 5.6 0.1 3.0 2 1 0 2 2 2 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 CAR23425.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4149 PF13664.1 CAR23426.1 - 0.17 11.9 0.8 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) zf-C3HC4_3 PF13920.1 CAR23427.1 - 1.2e-07 31.2 11.9 2.5e-07 30.2 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AICARFT_IMPCHas PF01808.13 CAR23429.1 - 6.3e-121 403.2 0.0 8.5e-121 402.8 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CAR23429.1 - 1.6e-25 88.8 0.2 5.8e-25 87.0 0.0 1.9 2 0 0 2 2 2 1 MGS-like domain Ribosomal_L15e PF00827.12 CAR23430.1 - 9e-90 299.3 13.4 1e-89 299.1 9.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 SOG2 PF10428.4 CAR23432.1 - 2.7 6.5 20.1 3.7 6.1 13.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Bindin PF02084.10 CAR23432.1 - 3 7.8 4.7 3.7 7.5 3.2 1.1 1 0 0 1 1 1 0 Bindin DUF2146 PF10220.4 CAR23432.1 - 4.3 5.1 6.9 5.1 4.9 4.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Herpes_pp85 PF04637.7 CAR23432.1 - 7.3 4.7 8.5 8.8 4.4 5.9 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Herpes_UL32 PF06070.6 CAR23432.1 - 8.2 4.7 14.2 8.7 4.6 9.9 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Pkr1 PF08636.5 CAR23433.1 - 1.5e-31 108.2 10.3 1.9e-31 107.9 7.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 MIF4G_like PF09088.6 CAR23435.1 - 2.7e-60 203.1 1.4 5.5e-60 202.0 1.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CAR23435.1 - 9.3e-48 162.6 2.8 9.3e-48 162.6 2.0 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.14 CAR23435.1 - 4.3e-14 52.4 1.8 4.3e-14 52.4 1.3 2.2 2 0 0 2 2 2 1 MIF4G domain Pox_polyA_pol_N PF12630.2 CAR23435.1 - 0.0029 17.6 2.2 0.034 14.2 0.2 3.3 3 0 0 3 3 3 1 Poxvirus poly(A) polymerase N-terminal domain DUF4129 PF13559.1 CAR23436.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) SNF2_N PF00176.18 CAR23437.1 - 3.8e-68 229.4 0.3 7e-68 228.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CAR23437.1 - 3.1e-14 52.7 0.0 6.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 CAR23437.1 - 3.1e-10 39.7 0.0 9.1e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 CAR23437.1 - 8.4e-09 34.9 9.4 1.5e-08 34.1 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR23437.1 - 6.6e-08 32.0 6.7 1.1e-07 31.3 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR23437.1 - 8.3e-08 31.9 7.6 1.6e-07 31.0 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAR23437.1 - 1.3e-07 31.4 9.0 2.6e-07 30.5 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR23437.1 - 1.8e-07 30.7 8.2 3.2e-07 29.9 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 CAR23437.1 - 1.4e-06 27.9 0.0 3.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-Apc11 PF12861.2 CAR23437.1 - 0.00095 18.9 0.2 0.0019 18.0 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CAR23437.1 - 0.0012 18.8 1.1 0.0025 17.8 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CAR23437.1 - 0.0037 16.9 4.0 0.0093 15.6 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 CAR23437.1 - 0.01 15.3 6.8 0.028 13.9 4.7 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CAR23437.1 - 0.01 15.7 8.8 0.024 14.5 6.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CAR23437.1 - 0.089 12.3 6.3 0.17 11.5 4.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CAR23437.1 - 0.24 11.2 2.2 0.56 10.0 1.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 CAR23437.1 - 0.48 10.4 6.0 0.97 9.4 4.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.2 CAR23437.1 - 1.2 9.0 4.2 2.3 8.0 2.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon MOZ_SAS PF01853.13 CAR23438.1 - 1.2e-60 203.9 0.1 1.6e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 CAR23438.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HA2 PF04408.18 CAR23439.1 - 4.8e-25 87.5 0.0 2.1e-24 85.4 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR23439.1 - 6.1e-14 51.8 0.0 1.9e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAR23439.1 - 2.5e-13 49.6 0.0 9.9e-13 47.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR23439.1 - 6.1e-08 32.3 0.1 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR23439.1 - 2e-07 31.1 0.5 1e-05 25.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CAR23439.1 - 0.0022 17.1 0.7 0.0054 15.8 0.0 2.0 2 0 0 2 2 2 1 KaiC UPF0079 PF02367.12 CAR23439.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 CAR23439.1 - 0.026 13.4 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 CAR23439.1 - 0.027 13.6 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein HTH_37 PF13744.1 CAR23439.1 - 0.27 11.0 5.8 0.11 12.3 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Bromodomain PF00439.20 CAR23440.1 - 0.021 14.7 0.1 0.071 13.0 0.0 2.1 2 1 0 2 2 2 0 Bromodomain Nramp PF01566.13 CAR23441.1 - 2.6e-97 325.8 18.1 3.8e-97 325.2 12.5 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Y_Y_Y PF07495.8 CAR23442.1 - 0.0036 17.0 1.0 1.1 9.0 0.3 2.9 2 0 0 2 2 2 2 Y_Y_Y domain HAD_2 PF13419.1 CAR23443.1 - 2.1e-11 44.3 0.1 7e-11 42.6 0.0 1.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR23443.1 - 0.00026 20.6 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like COX6B PF02297.12 CAR23444.1 - 8.4e-21 73.7 3.7 9.8e-21 73.5 2.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 CAR23444.1 - 0.088 12.7 0.5 0.2 11.6 0.3 1.6 1 1 0 1 1 1 0 CHCH domain RIC1 PF07064.8 CAR23445.1 - 1.6e-14 53.9 0.1 6.6e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 RIC1 LLGL PF08366.8 CAR23445.1 - 0.066 13.1 0.0 0.65 9.9 0.0 2.6 1 1 1 2 2 2 0 LLGL2 DUF4176 PF13780.1 CAR23445.1 - 0.11 12.2 0.1 3 7.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) CAF1C_H4-bd PF12265.3 CAR23446.1 - 5.7e-19 67.7 0.0 1.5e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CAR23446.1 - 3.1e-18 64.8 10.4 4.9e-07 29.3 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoplasmin PF03066.10 CAR23446.1 - 0.022 14.2 1.0 0.022 14.2 0.7 2.7 2 0 0 2 2 2 0 Nucleoplasmin TEX19 PF15553.1 CAR23446.1 - 9.6 6.0 9.7 1.9 8.3 2.2 2.5 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF814 PF05670.8 CAR23447.1 - 3.2e-17 62.1 0.0 6.1e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Ku_C PF03730.9 CAR23447.1 - 0.089 13.3 2.1 0.16 12.5 1.5 1.3 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Meiotic_rec114 PF03525.9 CAR23448.1 - 7.9e-11 41.0 5.4 1.4e-10 40.1 3.8 1.5 1 1 0 1 1 1 1 Meiotic recombination protein rec114 CLTH PF10607.4 CAR23451.1 - 5e-27 94.3 2.9 1.9e-26 92.4 1.1 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.22 CAR23453.1 - 3.6e-14 51.7 2.2 7.6e-14 50.7 1.5 1.5 1 0 0 1 1 1 1 GATA zinc finger DRMBL PF07522.9 CAR23454.1 - 8.4e-25 86.9 0.4 1.7e-24 85.9 0.3 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CAR23454.1 - 2.5e-09 36.9 0.6 7.5e-09 35.4 0.4 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Arf PF00025.16 CAR23455.1 - 3.1e-44 150.2 0.0 3.7e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CAR23455.1 - 3.2e-12 45.8 1.1 4e-07 29.0 0.2 2.9 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAR23455.1 - 2.8e-11 42.9 0.0 3.4e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CAR23455.1 - 1.1e-06 28.1 0.0 1.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR23455.1 - 1.3e-06 28.8 0.0 2.6e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CAR23455.1 - 3.2e-06 27.0 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR23455.1 - 0.00036 19.8 0.1 0.00085 18.6 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CAR23455.1 - 0.0011 18.4 0.0 0.01 15.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CAR23455.1 - 0.0011 18.1 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CAR23455.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ldh_1_N PF00056.18 CAR23456.1 - 3.8e-45 153.1 0.1 6.5e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAR23456.1 - 7.3e-37 126.7 0.0 1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CAR23456.1 - 8.3e-05 21.4 0.0 0.00012 20.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CAR23456.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CAR23456.1 - 0.59 10.1 2.5 1.3 9.0 0.6 2.3 2 1 0 2 2 2 0 NADH(P)-binding DUF4410 PF14366.1 CAR23457.1 - 0.084 12.5 0.6 0.12 12.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) Asp-B-Hydro_N PF05279.6 CAR23457.1 - 0.11 12.3 0.4 0.11 12.2 0.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.20 CAR23458.1 - 8.4e-63 211.9 0.0 1e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23458.1 - 6.1e-28 97.5 0.0 9.7e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR23458.1 - 4.5e-05 23.3 0.4 0.0019 17.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAR23458.1 - 0.0003 20.4 0.1 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Epimerase PF01370.16 CAR23459.1 - 1.7e-15 57.0 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR23459.1 - 5.6e-12 44.9 0.0 8e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 CAR23459.1 - 5.5e-08 32.6 0.0 1.8e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 CAR23459.1 - 8.5e-08 32.2 0.0 2.9e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CAR23459.1 - 2.8e-07 29.7 0.1 1.1e-06 27.7 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CAR23459.1 - 5.2e-05 23.3 0.0 0.00017 21.6 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 CAR23459.1 - 0.081 12.8 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TPP_enzyme_N PF02776.13 CAR23460.1 - 3e-29 101.6 0.0 7.2e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR23460.1 - 1.7e-27 95.8 0.0 4.1e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CAR23460.1 - 1.3e-15 57.3 0.0 2.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 CAR23460.1 - 0.01 14.6 0.1 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component zf-H2C2_2 PF13465.1 CAR23461.1 - 2.1e-21 75.0 28.4 3.4e-09 36.5 0.9 4.4 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 CAR23461.1 - 7.1e-20 70.0 32.4 1.1e-05 25.4 0.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR23461.1 - 1.2e-13 50.3 28.1 0.00039 20.5 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.7 CAR23461.1 - 0.088 12.9 9.5 0.58 10.3 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding COPI_C PF06957.6 CAR23461.1 - 0.16 10.4 3.6 3.1 6.2 0.2 2.5 2 1 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus zf-met PF12874.2 CAR23461.1 - 0.21 11.8 14.1 11 6.3 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-CHCC PF10276.4 CAR23461.1 - 0.36 10.7 13.2 1.2 9.0 0.7 3.4 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_jaz PF12171.3 CAR23461.1 - 3 8.0 16.2 8.3 6.6 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Adeno_E1B_19K PF01691.11 CAR23462.1 - 0.051 12.8 0.2 0.15 11.3 0.1 1.8 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen Pox_D5 PF03288.11 CAR23462.1 - 0.36 11.1 2.8 0.48 10.7 0.8 2.1 2 1 0 2 2 2 0 Poxvirus D5 protein-like TRAPP PF04051.11 CAR23463.1 - 6.8e-34 116.5 0.0 9.1e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SH3_9 PF14604.1 CAR23464.1 - 4.1e-26 90.3 0.3 3.6e-15 55.2 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 CAR23464.1 - 7.8e-24 82.8 0.1 1.4e-13 49.9 0.0 2.8 2 0 0 2 2 2 2 SH3 domain FCH PF00611.18 CAR23464.1 - 1.1e-23 83.2 0.5 1.1e-23 83.2 0.4 2.8 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 CAR23464.1 - 1.5e-17 62.8 0.0 1.1e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain DUF4463 PF14703.1 CAR23464.1 - 6 7.4 10.5 0.75 10.3 2.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DUF2417 PF10329.4 CAR23465.1 - 4.1e-62 209.6 3.9 6.6e-62 208.9 2.7 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 CAR23465.1 - 8.1e-09 35.6 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR23465.1 - 1.7e-07 31.0 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3278 PF11683.3 CAR23465.1 - 1.5 8.8 7.0 0.054 13.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) FHA PF00498.21 CAR23466.1 - 3.2e-15 55.9 0.1 6.1e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CAR23466.1 - 1.4e-06 28.0 10.0 2.3e-06 27.3 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR23466.1 - 5.3e-05 23.2 3.5 0.0001 22.3 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CAR23466.1 - 0.00085 18.9 10.4 0.0014 18.2 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR23466.1 - 0.0022 17.6 8.3 0.0035 17.0 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CAR23466.1 - 0.0085 15.9 4.3 0.015 15.0 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Sec_GG PF07549.9 CAR23466.1 - 0.012 14.8 0.1 0.028 13.6 0.1 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-C3HC4_2 PF13923.1 CAR23466.1 - 0.018 15.0 11.7 0.03 14.3 8.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CAR23466.1 - 0.13 12.3 7.2 0.26 11.3 5.0 1.5 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.1 CAR23466.1 - 0.13 12.4 4.1 0.25 11.4 2.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 CAR23466.1 - 0.15 11.7 6.8 0.25 11.0 4.7 1.4 1 0 0 1 1 1 0 PHD-finger Malate_synthase PF01274.17 CAR23467.1 - 1.6e-216 719.3 0.0 2e-216 719.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 CAR23467.1 - 0.025 13.4 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Aminotran_3 PF00202.16 CAR23468.1 - 2e-97 326.0 0.0 2.6e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TMEM52 PF14979.1 CAR23468.1 - 0.011 15.6 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane 52 PhyH PF05721.8 CAR23469.1 - 3.3e-29 102.4 0.1 4.3e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-C2H2 PF00096.21 CAR23470.1 - 1e-06 28.6 9.3 0.00081 19.5 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR23470.1 - 9.4e-06 25.6 9.7 0.012 15.8 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR23470.1 - 4.1e-05 23.6 12.5 8.5e-05 22.6 3.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain Rad9_Rad53_bind PF08605.5 CAR23471.1 - 5.9e-35 119.9 0.0 1.1e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 CAR23471.1 - 1.1e-05 25.4 1.0 2.2e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Nucleo_P87 PF07267.6 CAR23473.1 - 0.021 13.5 0.4 0.031 12.9 0.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box PF00646.28 CAR23474.1 - 3.2e-08 32.9 0.3 6.7e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CAR23474.1 - 1.6e-06 27.7 0.0 3.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like NAD_binding_10 PF13460.1 CAR23475.1 - 6.7e-25 88.1 0.0 9.5e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CAR23475.1 - 2.8e-14 52.9 0.1 1.5e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.16 CAR23475.1 - 2.5e-05 23.8 0.0 0.021 14.2 0.0 2.4 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CAR23475.1 - 0.00026 20.1 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 CAR23475.1 - 0.00035 20.5 0.1 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 CAR23475.1 - 0.00073 18.3 0.0 0.0013 17.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CAR23475.1 - 0.092 12.6 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase PRKCSH-like PF12999.2 CAR23476.1 - 4.2e-41 140.4 8.6 4.2e-41 140.4 6.0 2.3 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CAR23476.1 - 6.9e-21 74.3 0.1 1.4e-19 70.1 0.0 2.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CAR23476.1 - 5.4e-05 23.9 0.0 0.00016 22.3 0.0 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DCX PF03607.12 CAR23476.1 - 0.063 12.8 0.5 16 5.1 0.0 3.3 3 0 0 3 3 3 0 Doublecortin Retrotrans_gag PF03732.12 CAR23476.1 - 0.26 11.3 4.3 16 5.6 0.2 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein Svf1 PF08622.5 CAR23477.1 - 2.3e-86 289.7 0.0 2.7e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Svf1-like CRF1 PF10380.4 CAR23478.1 - 2.6e-34 118.2 1.1 2.6e-34 118.2 0.8 3.7 4 1 0 4 4 4 1 Transcription factor CRF1 WD40 PF00400.27 CAR23479.1 - 1.7e-58 192.5 25.7 8e-09 35.0 0.2 11.8 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.6 CAR23479.1 - 5.3e-46 155.7 0.5 8.8e-46 155.0 0.3 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CAR23479.1 - 2.2e-06 26.0 11.1 0.11 10.6 0.1 5.4 4 1 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR23479.1 - 0.0012 17.6 0.8 0.82 8.3 0.0 4.4 2 1 2 4 4 4 1 Nup133 N terminal like Rsa3 PF14615.1 CAR23480.1 - 4.4e-21 73.8 0.0 8e-21 73.0 0.0 1.5 1 1 0 1 1 1 1 Ribosome-assembly protein 3 DUF3091 PF11291.3 CAR23480.1 - 0.43 10.5 4.3 0.17 11.8 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) SURF6 PF04935.7 CAR23480.1 - 0.46 9.7 12.2 0.79 8.9 8.5 1.3 1 1 0 1 1 1 0 Surfeit locus protein 6 SR-25 PF10500.4 CAR23480.1 - 1.4 8.3 19.5 1.3 8.4 12.9 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein VIT1 PF01988.14 CAR23481.1 - 1.8e-57 194.2 1.1 2.2e-57 193.9 0.8 1.1 1 0 0 1 1 1 1 VIT family DUF1517 PF07466.6 CAR23481.1 - 0.19 10.7 0.5 0.36 9.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Histone PF00125.19 CAR23482.1 - 8.3e-22 77.1 0.2 1.2e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR23482.1 - 7.6e-06 25.9 0.1 7.6e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CAR23482.1 - 0.0016 18.6 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 CAR23482.1 - 0.015 13.9 3.7 0.018 13.7 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1018 PF06252.7 CAR23482.1 - 0.14 12.7 0.7 0.19 12.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 CAR23483.1 - 1.9e-25 88.7 0.0 2.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR23483.1 - 1.7e-05 24.7 0.0 2.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DLIC PF05783.6 CAR23483.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RAP1 PF07218.6 CAR23484.1 - 2.9 5.8 7.5 4.8 5.1 5.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ADK PF00406.17 CAR23485.1 - 5.2e-59 198.4 0.0 6.2e-59 198.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CAR23485.1 - 3.7e-15 55.2 0.0 8.7e-15 54.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CAR23485.1 - 3.3e-05 23.8 0.0 6.6e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR23485.1 - 0.00055 20.2 0.0 0.0012 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR23485.1 - 0.00062 20.5 0.0 0.0011 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR23485.1 - 0.04 13.0 0.0 0.088 11.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 CAR23485.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain CFIA_Pcf11 PF11526.3 CAR23487.1 - 1.5e-22 79.5 2.3 1.5e-22 79.5 1.6 2.1 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 CAR23487.1 - 0.00021 20.9 0.7 0.00076 19.1 0.0 2.3 2 0 0 2 2 2 1 VHS domain Spore_II_R PF09551.5 CAR23487.1 - 0.045 13.7 5.3 0.15 12.0 3.7 1.8 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) zf-H2C2_2 PF13465.1 CAR23487.1 - 0.69 10.3 3.0 21 5.6 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double domain PAT1 PF09770.4 CAR23487.1 - 1 7.4 26.4 1.4 7.0 18.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRN7 PF11781.3 CAR23487.1 - 1.5 8.3 3.8 12 5.4 0.1 2.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_2 PF13639.1 CAR23487.1 - 2.2 8.2 5.8 1.9 8.3 1.6 2.7 2 1 1 3 3 3 0 Ring finger domain Totivirus_coat PF05518.6 CAR23487.1 - 3.2 5.4 8.0 5.1 4.7 5.6 1.2 1 0 0 1 1 1 0 Totivirus coat protein LIM PF00412.17 CAR23487.1 - 6.1 7.0 8.7 8.2 6.5 0.2 3.0 3 0 0 3 3 3 0 LIM domain Activator_LAG-3 PF11498.3 CAR23487.1 - 8.3 5.0 31.0 17 4.0 21.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Mito_carr PF00153.22 CAR23488.1 - 6.4e-28 96.3 0.2 4.7e-14 51.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-bind_4 PF13837.1 CAR23489.1 - 0.0002 21.4 0.0 0.00066 19.7 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR23489.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sugar_tr PF00083.19 CAR23491.1 - 4.6e-98 328.7 16.3 5.4e-98 328.4 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR23491.1 - 4.4e-28 98.0 21.7 1.5e-27 96.2 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SdpI PF13630.1 CAR23491.1 - 1.4 8.6 10.7 2.4 7.9 0.5 3.3 3 0 0 3 3 3 0 SdpI/YhfL protein family Methyltransf_4 PF02390.12 CAR23492.1 - 1.2e-58 197.4 0.1 1.7e-58 196.9 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 CAR23492.1 - 3.1e-05 23.9 0.0 8.2e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR23492.1 - 0.0003 21.3 0.0 0.00072 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR23492.1 - 0.0019 17.7 0.0 0.0035 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR23492.1 - 0.0055 17.1 0.2 0.018 15.5 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 CAR23492.1 - 0.0081 15.5 0.1 0.021 14.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CAR23492.1 - 0.013 15.8 0.1 0.045 14.1 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Ubie_methyltran PF01209.13 CAR23492.1 - 0.027 13.5 0.0 0.095 11.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FmrO PF07091.6 CAR23492.1 - 0.079 11.9 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF3958 PF13125.1 CAR23492.1 - 0.14 12.1 1.8 0.16 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Ribosomal_L10 PF00466.15 CAR23493.1 - 3.8e-09 36.3 0.0 6.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3767 PF12597.3 CAR23495.1 - 1.3e-44 150.6 0.2 1.7e-44 150.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3353 PF11833.3 CAR23495.1 - 0.024 14.0 0.5 0.042 13.2 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) YrhK PF14145.1 CAR23495.1 - 0.088 12.4 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 YrhK-like protein Sel1 PF08238.7 CAR23496.1 - 7.1e-31 105.9 39.1 1.7e-06 28.4 0.9 8.1 7 0 0 7 7 7 7 Sel1 repeat Aminotran_1_2 PF00155.16 CAR23497.1 - 1.3e-74 251.4 0.4 1.6e-74 251.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CAR23497.1 - 3.1e-08 32.2 0.0 5e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CAR23497.1 - 6.1e-07 28.5 0.1 2.4e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Preseq_ALAS PF09029.5 CAR23497.1 - 0.049 13.6 1.1 0.15 12.0 0.8 1.8 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Reticulon PF02453.12 CAR23498.1 - 9.3e-38 129.4 1.5 1.3e-37 128.9 1.0 1.2 1 0 0 1 1 1 1 Reticulon Aconitase PF00330.15 CAR23499.1 - 2.5e-74 250.4 0.4 4.7e-49 167.1 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAR23499.1 - 1.7e-31 109.0 0.0 4.2e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain YflT PF11181.3 CAR23499.1 - 0.014 15.5 0.1 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Heat induced stress protein YflT Porphobil_deam PF01379.15 CAR23500.1 - 2e-81 271.9 0.0 3e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CAR23500.1 - 7e-21 74.1 0.3 1.3e-20 73.2 0.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain TPR_14 PF13428.1 CAR23501.1 - 0.021 15.4 0.0 5 8.0 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Na_Ca_ex PF01699.19 CAR23502.1 - 3.9e-44 149.6 29.9 2.2e-24 85.6 2.3 3.3 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF788 PF05620.6 CAR23502.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF788) Flavokinase PF01687.12 CAR23503.1 - 2.1e-30 105.1 0.0 2.5e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase GLE1 PF07817.8 CAR23504.1 - 2.7e-88 295.2 0.1 2.7e-88 295.2 0.1 1.9 2 1 1 3 3 3 1 GLE1-like protein ERM PF00769.14 CAR23504.1 - 0.03 13.8 33.7 0.047 13.2 23.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3610 PF12272.3 CAR23504.1 - 0.077 12.6 0.2 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) MAP7 PF05672.6 CAR23504.1 - 0.18 11.1 44.6 0.39 10.0 30.9 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 CAR23504.1 - 0.28 10.5 47.6 0.46 9.8 33.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 CAR23504.1 - 3.8 7.2 21.9 6 6.6 15.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L5_C PF00673.16 CAR23505.1 - 1.2e-21 76.1 0.0 2.4e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CAR23505.1 - 3.5e-06 26.7 0.0 6.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Adaptin_N PF01602.15 CAR23506.1 - 3.2e-104 349.1 8.6 4.7e-104 348.6 5.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CAR23506.1 - 3.7e-59 198.1 0.0 1.1e-58 196.6 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CAR23506.1 - 4.3e-52 175.5 0.2 1e-51 174.2 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CAR23506.1 - 6.5e-06 26.3 8.6 0.009 16.2 0.0 4.3 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 CAR23506.1 - 0.0018 18.1 8.2 0.27 11.0 1.3 3.3 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CAR23506.1 - 0.036 14.4 2.2 0.52 10.7 0.1 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Ribosomal_L7Ae PF01248.21 CAR23509.1 - 6.6e-27 92.8 0.2 9.2e-27 92.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cpn60_TCP1 PF00118.19 CAR23509.1 - 0.029 12.9 0.1 0.037 12.6 0.1 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Metallophos PF00149.23 CAR23510.1 - 1.9e-09 37.2 0.9 3.8e-09 36.2 0.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR23510.1 - 0.00027 20.8 0.0 0.0006 19.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 CAR23511.1 - 4.4e-07 29.4 0.1 2.9e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR23511.1 - 0.00011 22.0 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR23511.1 - 0.035 14.0 0.0 0.086 12.8 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR23511.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DEAD PF00270.24 CAR23512.1 - 8e-48 162.1 0.1 1.7e-45 154.5 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR23512.1 - 2.8e-26 91.1 0.2 5.7e-26 90.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR23512.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CAR23512.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FA_desaturase PF00487.19 CAR23513.1 - 8.7e-21 74.5 19.8 1.4e-20 73.8 13.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CAR23513.1 - 8.3e-07 29.1 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TPR_11 PF13414.1 CAR23514.1 - 5.4e-25 86.8 2.5 1.3e-11 43.9 0.5 4.3 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 CAR23514.1 - 2.3e-23 80.7 1.8 2.5e-07 30.0 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CAR23514.1 - 1.5e-20 71.4 2.9 3.4e-06 26.5 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAR23514.1 - 2.1e-17 62.0 1.2 0.00024 21.4 0.1 6.3 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAR23514.1 - 1.6e-14 52.8 0.6 0.0089 16.1 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CAR23514.1 - 2.9e-13 50.1 0.3 1.1e-06 29.1 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CAR23514.1 - 1.2e-12 47.9 1.1 0.00011 22.4 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAR23514.1 - 3.2e-10 39.0 1.0 0.0029 17.2 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR23514.1 - 9.7e-10 38.2 1.3 1.7e-05 24.6 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 CAR23514.1 - 3.3e-08 33.5 1.9 0.083 13.0 0.0 5.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR23514.1 - 5.1e-08 32.1 0.5 0.27 11.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR23514.1 - 4.2e-06 26.5 0.3 0.013 15.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAR23514.1 - 4.3e-05 23.6 0.2 24 5.6 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 CAR23514.1 - 0.011 16.0 0.8 0.027 14.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial transcriptional activator domain CCP_MauG PF03150.9 CAR23514.1 - 0.036 14.3 3.9 0.12 12.6 2.7 2.0 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase Glyco_transf_34 PF05637.7 CAR23515.1 - 7.1e-74 248.3 0.0 8.7e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 CAR23515.1 - 0.0062 15.8 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF273 ARID PF01388.16 CAR23516.1 - 1.5e-22 79.2 0.4 1.5e-22 79.2 0.3 3.0 3 1 1 4 4 4 1 ARID/BRIGHT DNA binding domain ERCC4 PF02732.10 CAR23517.1 - 1.3e-25 89.8 0.0 3.1e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain MTHFR PF02219.12 CAR23518.1 - 1.3e-108 362.4 0.0 1.8e-108 362.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Nse4_C PF08743.5 CAR23519.1 - 0.08 12.9 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Nse4 C-terminal Sybindin PF04099.7 CAR23520.1 - 1.5e-35 122.0 0.2 1.1e-33 115.8 0.1 2.0 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CAR23520.1 - 9.2e-08 32.0 0.0 1.1e-07 31.8 0.0 1.2 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region NUP PF06516.6 CAR23521.1 - 2.5e-114 381.3 0.5 3.5e-114 380.8 0.3 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.20 CAR23522.1 - 3.7e-46 157.3 0.0 5.9e-45 153.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23522.1 - 1.8e-19 69.8 0.0 6.7e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR23522.1 - 8.1e-08 31.5 0.0 2.5e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CAR23522.1 - 0.003 16.4 0.1 0.01 14.6 0.0 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CAR23522.1 - 0.0032 17.2 0.1 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR23522.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APS_kinase PF01583.15 CAR23523.1 - 2.9e-09 36.7 0.0 4.5e-09 36.1 0.0 1.2 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 CAR23523.1 - 2.5e-06 28.2 0.0 3.6e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 CAR23523.1 - 1.1e-05 25.3 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 CAR23523.1 - 6.5e-05 23.2 0.0 0.00011 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 CAR23523.1 - 9.7e-05 21.8 0.0 0.0002 20.8 0.0 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 CAR23523.1 - 0.00019 21.0 0.1 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR23523.1 - 0.00025 20.2 0.0 0.00048 19.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 CAR23523.1 - 0.00079 19.1 0.1 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CAR23523.1 - 0.0014 18.6 0.0 0.0048 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 CAR23523.1 - 0.0016 18.7 0.0 0.0019 18.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 CAR23523.1 - 0.0042 17.2 0.0 0.0065 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CAR23523.1 - 0.008 15.7 0.0 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 CAR23523.1 - 0.0094 15.6 0.0 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.1 CAR23523.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CAR23523.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 CAR23523.1 - 0.017 14.0 0.0 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF258 PF03193.11 CAR23523.1 - 0.017 14.3 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 CAR23523.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Guanylate_kin PF00625.16 CAR23523.1 - 0.028 13.8 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase KTI12 PF08433.5 CAR23523.1 - 0.042 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 CAR23523.1 - 0.059 13.0 0.2 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CAR23523.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CAR23523.1 - 0.064 13.1 0.0 0.26 11.1 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.1 CAR23523.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CAR23523.1 - 0.09 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.4 CAR23523.1 - 0.093 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.9 CAR23523.1 - 0.097 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_25 PF13481.1 CAR23523.1 - 0.1 11.9 0.3 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 CAR23523.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.11 CAR23523.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 CAR23523.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Torsin 6PF2K PF01591.13 CAR23523.1 - 0.17 10.9 0.2 0.45 9.5 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Thiolase_N PF00108.18 CAR23524.1 - 1.4e-101 338.9 1.4 1.9e-101 338.5 1.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CAR23524.1 - 9.9e-45 150.9 2.8 1.5e-44 150.3 0.1 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CAR23524.1 - 4.1e-06 26.4 1.9 8.6e-06 25.4 1.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SUV3_C PF12513.3 CAR23525.1 - 7.5e-19 66.9 1.8 1.8e-18 65.6 1.3 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CAR23525.1 - 6e-13 48.4 0.0 1.7e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AdoMet_MTase PF07757.8 CAR23526.1 - 4.7e-42 142.6 0.2 8.5e-42 141.8 0.1 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.1 CAR23526.1 - 0.008 15.7 0.3 0.017 14.7 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CAR23526.1 - 0.078 12.3 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Pkinase PF00069.20 CAR23527.1 - 5.2e-77 258.4 0.0 6.1e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23527.1 - 4.1e-37 127.6 0.0 5.8e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23527.1 - 0.00083 18.3 0.0 0.0014 17.6 0.0 1.5 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CAR23527.1 - 0.004 16.9 0.0 0.071 12.8 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family ApbA_C PF08546.6 CAR23529.1 - 7.5e-06 25.9 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CAR23529.1 - 8.7e-06 25.2 0.0 2.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FlxA PF14282.1 CAR23529.1 - 0.036 14.0 4.4 0.14 12.0 3.0 2.1 1 0 0 1 1 1 0 FlxA-like protein Ax_dynein_light PF10211.4 CAR23529.1 - 0.41 10.4 7.2 0.12 12.2 0.4 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain DUF1043 PF06295.7 CAR23529.1 - 0.81 9.3 7.8 0.061 12.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) NAC PF01849.13 CAR23530.1 - 8.9e-17 60.3 0.1 1.4e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 NAC domain HIF-1a_CTAD PF08778.5 CAR23530.1 - 0.096 12.1 0.1 3.4 7.2 0.0 3.0 3 1 0 3 3 3 0 HIF-1 alpha C terminal transactivation domain TT_ORF2 PF02957.10 CAR23530.1 - 4.9 7.8 7.4 7 7.3 0.3 2.1 2 0 0 2 2 2 0 TT viral ORF2 zf-C2H2_4 PF13894.1 CAR23531.1 - 1.1e-11 44.1 1.5 9.4e-05 22.4 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR23531.1 - 2.9e-10 39.8 5.7 1.7e-05 24.8 0.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CAR23531.1 - 0.0015 18.6 0.6 0.19 11.8 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR23531.1 - 0.0032 17.6 0.1 0.41 10.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CAR23531.1 - 0.0033 17.6 5.8 0.7 10.2 0.3 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 CAR23531.1 - 0.034 14.0 4.3 0.12 12.3 0.1 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger YwqJ-deaminase PF14431.1 CAR23531.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 YwqJ-like deaminase zf-BED PF02892.10 CAR23531.1 - 0.52 10.1 2.3 17 5.2 0.5 2.5 2 0 0 2 2 2 0 BED zinc finger tRNA-synt_1 PF00133.17 CAR23532.1 - 4.5e-158 526.9 0.0 6e-158 526.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CAR23532.1 - 2.9e-21 75.5 0.0 3.7e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CAR23532.1 - 3.5e-20 72.2 0.6 8.5e-20 71.0 0.4 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 CAR23532.1 - 0.0085 15.7 4.1 0.021 14.4 2.8 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS FLILHELTA PF10306.4 CAR23533.1 - 1.4e-23 82.7 0.0 2.2e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Pkinase PF00069.20 CAR23534.1 - 4.2e-56 189.9 0.0 7.2e-54 182.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23534.1 - 3.2e-26 91.9 0.0 4.9e-25 88.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23534.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.17 CAR23535.1 - 4.5e-57 189.6 1.8 2.1e-17 62.5 0.2 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR23535.1 - 7.4e-46 154.0 0.6 2.5e-13 49.8 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR23535.1 - 4.5e-20 71.2 1.3 6.3e-08 32.3 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-N PF05238.8 CAR23536.1 - 3.6e-70 237.0 0.0 4.3e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF4170 PF13773.1 CAR23536.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) Vps16_C PF04840.7 CAR23537.1 - 1.7e-71 240.7 6.3 2.7e-71 240.1 4.4 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 CAR23537.1 - 9.6e-63 212.1 0.0 1.5e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region DUF2732 PF10809.3 CAR23537.1 - 0.0042 16.6 0.2 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2732) Skp1_POZ PF03931.10 CAR23538.1 - 8.3e-13 48.2 0.2 3e-12 46.4 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CAR23538.1 - 2.1e-05 24.4 0.1 3e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 BTB/POZ domain ANTH PF07651.11 CAR23538.1 - 0.036 12.7 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 ANTH domain DnaI_N PF07319.6 CAR23538.1 - 0.041 14.1 0.1 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus zf-RING_UBOX PF13445.1 CAR23539.1 - 5.5e-14 51.6 3.7 1.6e-13 50.1 2.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CAR23539.1 - 1.3e-09 37.9 0.1 1.3e-09 37.9 0.0 2.0 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 CAR23539.1 - 0.0071 16.1 2.6 0.016 15.0 1.8 1.6 1 0 0 1 1 1 1 Ring finger domain Sgf11 PF08209.6 CAR23540.1 - 3.9e-16 58.0 2.3 5.3e-16 57.6 1.6 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 CAR23540.1 - 0.13 11.9 0.8 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Catalase PF00199.14 CAR23541.1 - 5.4e-173 575.0 2.1 7e-173 574.6 1.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CAR23541.1 - 2.4e-13 49.7 0.2 1.1e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive EF1G PF00647.14 CAR23542.1 - 1.3e-43 147.0 0.0 2.4e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 CAR23542.1 - 2e-09 37.4 0.0 7.2e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CAR23542.1 - 2.5e-08 33.8 2.5 3.2e-08 33.4 0.0 2.5 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAR23542.1 - 2.8e-08 33.5 0.4 6.4e-08 32.3 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CAR23542.1 - 0.0027 18.1 0.1 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CAR23542.1 - 0.0072 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FAM176 PF14851.1 CAR23543.1 - 0.088 12.4 1.9 0.22 11.1 1.3 1.6 1 0 0 1 1 1 0 FAM176 family SID-1_RNA_chan PF13965.1 CAR23543.1 - 0.12 10.5 0.4 0.17 10.0 0.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Anp1 PF03452.9 CAR23544.1 - 1.6e-109 365.2 0.0 1.9e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CAR23544.1 - 0.02 14.6 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Alk_phosphatase PF00245.15 CAR23545.1 - 1.7e-126 422.3 0.1 2e-126 422.1 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 CAR23545.1 - 4.9e-05 22.8 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CAR23545.1 - 0.022 13.9 0.1 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Sulfatase UPF0149 PF03695.8 CAR23545.1 - 0.079 12.8 0.2 1.1 9.1 0.0 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0149) Arf PF00025.16 CAR23546.1 - 2.5e-48 163.6 0.0 3e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CAR23546.1 - 9.5e-16 57.5 0.0 1.2e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR23546.1 - 4.3e-13 49.7 0.0 6.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CAR23546.1 - 1.4e-11 43.9 0.0 2.3e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CAR23546.1 - 2.6e-10 39.5 0.2 1.4e-05 23.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 CAR23546.1 - 4.7e-09 35.9 0.0 4e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR23546.1 - 5.7e-08 32.1 0.0 7.1e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAR23546.1 - 1.8e-07 31.0 0.0 4.5e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAR23546.1 - 0.0014 18.7 0.4 0.016 15.3 0.0 2.7 2 1 1 3 3 2 1 AAA domain FeoB_N PF02421.13 CAR23546.1 - 0.019 14.2 0.5 0.11 11.8 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Thymidylate_kin PF02223.12 CAR23546.1 - 0.028 13.8 0.4 0.066 12.5 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase PduV-EutP PF10662.4 CAR23546.1 - 0.07 12.6 0.3 5.3 6.5 0.0 2.8 2 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cwf21 PF08312.7 CAR23547.1 - 4.4e-13 48.8 2.3 9.8e-13 47.7 1.6 1.6 1 0 0 1 1 1 1 cwf21 domain DUF155 PF02582.9 CAR23547.1 - 0.15 11.9 2.2 0.17 11.8 0.9 1.4 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Tmemb_9 PF05434.6 CAR23547.1 - 1.9 8.1 5.9 0.56 9.9 1.2 1.9 1 1 1 2 2 2 0 TMEM9 ODC_AZ PF02100.12 CAR23548.1 - 1.5e-06 27.6 0.0 2.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Glyco_transf_15 PF01793.11 CAR23549.1 - 3.2e-142 473.3 10.4 4e-142 473.0 7.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase L_lactis_ph-MCP PF06673.6 CAR23549.1 - 0.044 12.5 0.2 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF4383 PF14325.1 CAR23549.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) TPR_11 PF13414.1 CAR23550.1 - 5.5e-16 57.9 9.8 4e-13 48.8 1.7 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CAR23550.1 - 5.1e-10 38.5 14.9 0.00056 19.3 1.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR23550.1 - 1.1e-07 31.1 14.2 0.021 14.7 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAR23550.1 - 6e-06 26.0 3.9 0.059 13.3 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR23550.1 - 3e-05 24.5 4.6 0.067 13.8 0.5 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 CAR23550.1 - 0.00093 19.2 8.7 0.0029 17.6 5.0 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 CAR23550.1 - 0.0026 16.3 2.4 0.0034 16.0 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 CAR23550.1 - 0.003 17.8 3.5 0.041 14.2 1.5 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR23550.1 - 0.0053 17.2 1.4 0.66 10.7 0.3 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR23550.1 - 0.11 12.3 11.6 0.049 13.5 0.9 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 CAR23550.1 - 0.53 10.6 5.6 0.15 12.3 0.5 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR23550.1 - 2.4 8.1 10.0 8.3 6.4 0.3 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Rpn3_C PF08375.6 CAR23550.1 - 4.3 7.8 9.6 2.9 8.3 1.2 3.3 3 1 0 3 3 3 0 Proteasome regulatory subunit C-terminal INCENP_ARK-bind PF03941.10 CAR23551.1 - 8.6e-19 67.1 1.3 2.1e-18 65.9 0.9 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region AA_permease PF00324.16 CAR23552.1 - 4.8e-81 272.5 36.8 9.2e-81 271.5 25.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23552.1 - 4.6e-27 94.6 38.9 4.5e-26 91.3 26.9 1.9 1 1 0 1 1 1 1 Amino acid permease Prp19 PF08606.6 CAR23552.1 - 0.2 11.3 1.4 1.5 8.6 1.0 2.1 1 1 0 1 1 1 0 Prp19/Pso4-like DUF2583 PF10762.4 CAR23552.1 - 0.36 10.9 3.5 2.9 8.1 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) zf-CCCH PF00642.19 CAR23554.1 - 1.5e-11 43.6 13.4 1.6e-06 27.6 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAR23554.1 - 0.063 13.2 16.4 0.21 11.6 1.9 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 CAR23554.1 - 0.17 11.4 2.0 11 5.6 0.1 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster ORC6 PF05460.8 CAR23554.1 - 8.1 5.4 7.4 11 5.0 5.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) LRR_7 PF13504.1 CAR23555.1 - 0.079 13.2 5.0 24 5.7 0.1 4.3 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 CAR23555.1 - 0.24 11.5 6.9 7.8 6.9 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat Lge1 PF11488.3 CAR23556.1 - 2e-22 79.1 1.4 2.9e-22 78.6 0.9 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.20 CAR23557.1 - 7.5e-24 84.5 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR23557.1 - 1.3e-07 31.4 0.0 2.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CAR23557.1 - 6.4e-07 29.3 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CAR23557.1 - 0.00099 19.1 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CAR23557.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 CAR23558.1 - 1.6e-74 250.3 0.0 1.9e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23558.1 - 1.8e-33 115.7 0.0 2.3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23558.1 - 3.1e-05 23.1 0.0 5.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR23558.1 - 0.00099 18.9 0.3 0.014 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR23558.1 - 0.025 13.6 0.1 0.072 12.1 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gly_transf_sug PF04488.10 CAR23559.1 - 1.1e-18 67.4 0.0 2.3e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CAR23559.1 - 0.047 12.1 1.1 3.1 6.1 0.1 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.4 CAR23560.1 - 4.4e-100 334.0 4.2 4.4e-100 334.0 2.9 1.9 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CAR23560.1 - 1.5e-30 105.1 0.3 7.5e-30 102.8 0.2 2.3 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Macoilin PF09726.4 CAR23560.1 - 0.63 8.2 25.4 0.97 7.6 17.6 1.2 1 0 0 1 1 1 0 Transmembrane protein MCLC PF05934.6 CAR23560.1 - 1.3 7.2 5.4 1.7 6.8 3.7 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF2413 PF10310.4 CAR23560.1 - 2.7 6.7 9.9 3.7 6.2 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2217 PF10265.4 CAR23560.1 - 4.7 5.8 16.7 6.8 5.3 11.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) UPF0233 PF06781.7 CAR23561.1 - 0.073 12.7 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Exo5 PF09810.4 CAR23562.1 - 1e-29 103.8 0.7 6.9e-29 101.0 0.5 2.2 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 CAR23562.1 - 0.00012 21.5 4.6 0.0029 17.0 3.2 2.7 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 CAR23562.1 - 0.01 15.7 5.2 0.47 10.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF83 Glutaredoxin PF00462.19 CAR23563.1 - 3.4e-18 65.3 0.0 5.3e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Amidase PF01425.16 CAR23564.1 - 4.7e-91 305.8 0.0 6.5e-91 305.3 0.0 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 CAR23564.1 - 3.9e-85 285.4 0.0 6.2e-85 284.7 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 CAR23564.1 - 6.3e-64 215.1 0.0 1.2e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 CAR23564.1 - 1.7e-43 148.4 0.0 3.4e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 CAR23564.1 - 1.6e-38 131.2 0.0 3.4e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAR23564.1 - 8.2e-34 115.8 0.0 2.3e-33 114.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CAR23564.1 - 1.7e-18 66.0 4.6 2.7e-18 65.3 1.3 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CAR23564.1 - 2.4e-18 66.5 0.0 6e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CAR23564.1 - 2.5e-11 43.3 0.0 5.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CAR23564.1 - 2.9e-06 26.7 0.0 6.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CAR23564.1 - 1.2e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CAR23564.1 - 0.00075 19.0 0.0 0.0055 16.2 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 CAR23564.1 - 0.0052 16.0 0.0 0.016 14.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 CAR23564.1 - 0.066 12.9 0.4 0.24 11.1 0.1 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Toxin_59 PF15537.1 CAR23564.1 - 0.068 13.2 0.2 0.75 9.8 0.0 2.7 3 0 0 3 3 2 0 Putative toxin 59 Biotin_lipoyl_2 PF13533.1 CAR23564.1 - 2.2 8.0 5.4 20 4.9 0.0 3.1 2 1 1 3 3 3 0 Biotin-lipoyl like FTR1 PF03239.9 CAR23565.1 - 2.8e-95 318.8 9.1 3.3e-95 318.5 6.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4229 PF14012.1 CAR23565.1 - 0.93 9.4 9.0 0.32 10.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) CorA PF01544.13 CAR23566.1 - 0.00021 20.4 6.7 0.00036 19.6 4.5 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF350 PF03994.9 CAR23566.1 - 0.021 14.5 0.6 0.2 11.4 1.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Glyco_transf_15 PF01793.11 CAR23567.1 - 7.8e-146 485.2 10.5 1e-145 484.8 7.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_A2E PF12382.3 CAR23567.1 - 0.089 12.5 0.1 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon peptidase DUF2424 PF10340.4 CAR23568.1 - 2.9e-42 144.6 0.0 1.9e-40 138.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 CAR23568.1 - 3.9e-22 78.8 0.0 5.2e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR23568.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR23568.1 - 0.0035 17.2 0.0 0.0081 16.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DRMBL PF07522.9 CAR23568.1 - 0.046 13.7 0.1 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Abhydrolase_6 PF12697.2 CAR23569.1 - 1.2e-29 103.8 0.0 1.4e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR23569.1 - 4.5e-18 65.3 0.0 6.7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR23569.1 - 4e-14 52.7 0.3 6e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2305 PF10230.4 CAR23569.1 - 1.9e-06 27.4 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 CAR23569.1 - 2.5e-05 23.9 0.0 0.00061 19.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CAR23569.1 - 2.6e-05 23.8 0.0 0.00034 20.2 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_2 PF02230.11 CAR23569.1 - 5.3e-05 22.7 1.9 0.087 12.2 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 CAR23569.1 - 0.00018 21.3 0.1 0.00042 20.1 0.0 1.7 1 1 1 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CAR23569.1 - 0.00061 19.0 0.0 0.043 13.0 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family LCAT PF02450.10 CAR23569.1 - 0.00096 18.2 0.4 0.0025 16.8 0.1 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Thioesterase PF00975.15 CAR23569.1 - 0.0012 19.0 0.1 0.0031 17.7 0.1 1.6 2 0 0 2 2 2 1 Thioesterase domain DUF1057 PF06342.7 CAR23569.1 - 0.0045 15.8 0.0 0.0075 15.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 CAR23569.1 - 0.0083 15.7 0.3 0.02 14.5 0.2 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF2424 PF10340.4 CAR23569.1 - 0.021 13.4 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF1749 PF08538.5 CAR23569.1 - 0.027 13.3 0.1 0.074 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_4 PF08386.5 CAR23569.1 - 0.034 14.0 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.9 CAR23569.1 - 0.059 11.8 0.0 2.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Ndr family Aldedh PF00171.17 CAR23570.1 - 4.4e-176 585.7 0.1 5.1e-176 585.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box-like PF12937.2 CAR23571.1 - 0.0026 17.4 0.0 0.0087 15.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like NIF PF03031.13 CAR23572.1 - 7.7e-43 145.9 0.0 1.4e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pro_isomerase PF00160.16 CAR23573.1 - 3.5e-12 46.8 0.0 6.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD KorB_C PF06613.6 CAR23573.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain VPS28 PF03997.7 CAR23574.1 - 7.9e-64 214.7 3.8 9.2e-64 214.5 2.6 1.0 1 0 0 1 1 1 1 VPS28 protein DUF1759 PF03564.10 CAR23574.1 - 0.027 14.2 0.8 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Arrestin_C PF02752.17 CAR23575.1 - 0.0056 16.7 0.3 0.085 12.9 0.1 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MCM PF00493.18 CAR23576.1 - 4.6e-134 446.3 0.0 8.2e-134 445.5 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR23576.1 - 3.4e-28 98.5 0.1 1.3e-27 96.6 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR23576.1 - 8.8e-07 28.2 0.1 0.00014 21.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAR23576.1 - 1.8e-05 24.4 0.0 5.6e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 CAR23576.1 - 0.00022 21.5 0.0 0.00072 19.9 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAR23576.1 - 0.095 12.3 0.0 0.31 10.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3605 PF12239.3 CAR23577.1 - 4.7e-38 130.5 0.0 5.5e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Spc7 PF08317.6 CAR23578.1 - 0.098 11.3 1.0 0.14 10.7 0.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DER1 PF04511.10 CAR23579.1 - 5.2e-30 104.4 6.3 7.1e-30 103.9 4.3 1.2 1 0 0 1 1 1 1 Der1-like family DUF4149 PF13664.1 CAR23579.1 - 0.0048 16.9 4.4 0.0082 16.1 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) Mg296 PF09644.5 CAR23579.1 - 0.0053 16.6 0.1 0.0089 15.8 0.1 1.4 1 0 0 1 1 1 1 Mg296 protein polyprenyl_synt PF00348.12 CAR23580.1 - 2.7e-40 137.8 0.0 3.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase VPS9 PF02204.13 CAR23581.1 - 1.9e-20 72.8 1.0 4.2e-20 71.7 0.7 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain BLUF PF04940.7 CAR23582.1 - 0.05 13.3 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Sensors of blue-light using FAD SH3_1 PF00018.23 CAR23584.1 - 2.3e-22 78.1 0.0 2.6e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain PX PF00787.19 CAR23584.1 - 3.8e-14 52.4 0.0 8.1e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 CAR23584.1 - 1.2e-11 43.9 0.3 1.8e-08 33.8 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CAR23584.1 - 1.9e-06 27.2 0.0 1.7e-05 24.2 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain PB1 PF00564.19 CAR23584.1 - 2e-06 27.3 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain UCH PF00443.24 CAR23585.1 - 2.1e-34 118.8 5.6 1.8e-31 109.2 1.4 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.24 CAR23586.1 - 1.4e-37 128.8 0.0 4.5e-37 127.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR23586.1 - 0.00018 21.6 0.4 0.015 15.4 0.2 2.9 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 CAR23586.1 - 0.00061 19.6 0.0 0.0065 16.3 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CAR23586.1 - 0.00096 18.2 0.0 0.0029 16.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CAR23586.1 - 0.0012 18.5 0.1 0.067 12.9 0.0 3.7 3 2 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CAR23586.1 - 0.0018 18.2 0.8 0.0056 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 CAR23586.1 - 0.0055 16.1 0.2 0.57 9.5 0.1 2.7 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CAR23586.1 - 0.041 13.0 0.3 0.11 11.6 0.2 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CAR23586.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.9 2 2 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CAR23586.1 - 1 10.1 5.3 0.51 11.1 0.1 2.7 2 2 0 2 2 2 0 AAA domain Orbi_VP5 PF00901.12 CAR23586.1 - 7.3 4.6 13.7 13 3.7 9.5 1.4 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 GCR1_C PF12550.3 CAR23587.1 - 5.3e-25 87.0 1.8 5.3e-25 87.0 1.3 2.1 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes WD40 PF00400.27 CAR23588.1 - 1.5e-58 192.6 15.2 2.1e-11 43.2 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CAR23588.1 - 1.7e-49 167.5 1.5 3.5e-49 166.5 1.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 CAR23588.1 - 1.3e-06 26.8 2.1 0.03 12.4 0.1 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 LisH PF08513.6 CAR23588.1 - 2.3e-05 23.9 0.0 4.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.11 CAR23588.1 - 0.014 13.7 0.1 0.52 8.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain GPI2 PF06432.6 CAR23589.1 - 2.8e-56 190.9 27.8 4.7e-56 190.1 19.3 1.3 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase SPC12 PF06645.8 CAR23589.1 - 0.37 10.6 14.1 0.28 11.0 1.7 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PGI PF00342.14 CAR23591.1 - 1.8e-226 752.2 1.4 2.1e-226 752.0 1.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase WD40 PF00400.27 CAR23592.1 - 4.3e-17 61.2 12.5 0.00055 19.7 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CAR23592.1 - 2.5e-16 59.3 1.0 6.2e-16 58.0 0.4 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Lactonase PF10282.4 CAR23592.1 - 0.0096 15.0 0.0 0.14 11.1 0.0 2.3 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller Mt_ATP-synt_B PF05405.9 CAR23593.1 - 4.1e-55 185.6 10.1 4.9e-55 185.4 7.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SLS PF14611.1 CAR23593.1 - 0.053 12.9 2.7 0.086 12.2 1.9 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator SRX PF09201.5 CAR23593.1 - 0.062 12.9 2.4 0.1 12.2 1.6 1.4 1 0 0 1 1 1 0 SRX DUF724 PF05266.9 CAR23593.1 - 0.26 10.8 6.7 0.6 9.6 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DASH_Duo1 PF08651.5 CAR23593.1 - 1.3 8.6 4.7 22 4.7 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 NpwBP PF12622.2 CAR23594.1 - 3.8e-13 49.6 1.2 5.7e-13 49.1 0.8 1.3 1 0 0 1 1 1 1 mRNA biogenesis factor Med8 PF10232.4 CAR23595.1 - 7.7e-41 140.0 0.3 9e-41 139.8 0.2 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 COG7 PF10191.4 CAR23595.1 - 0.0086 14.0 0.3 0.0098 13.8 0.2 1.1 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) Mito_carr PF00153.22 CAR23596.1 - 2.3e-78 258.0 1.1 6.1e-29 99.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 CAR23597.1 - 1.2e-38 130.8 5.2 1.4e-38 130.6 2.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Surface_Ag_2 PF01617.12 CAR23597.1 - 0.046 12.9 0.3 0.055 12.6 0.2 1.1 1 0 0 1 1 1 0 Surface antigen Ribosomal_S4 PF00163.14 CAR23598.1 - 3.6e-26 91.3 2.1 5.7e-26 90.7 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CAR23598.1 - 1.8e-11 43.2 0.4 5.5e-11 41.7 0.3 1.9 1 0 0 1 1 1 1 S4 domain HMGL-like PF00682.14 CAR23599.1 - 4.1e-73 245.9 0.7 5.7e-73 245.4 0.2 1.5 2 0 0 2 2 2 1 HMGL-like FliG_N PF14842.1 CAR23599.1 - 0.018 15.1 0.2 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 FliG N-terminal domain DUF3535 PF12054.3 CAR23600.1 - 8.1e-143 476.2 0.1 6.6e-142 473.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CAR23600.1 - 1.9e-78 263.3 0.0 3e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 CAR23600.1 - 1e-14 53.2 5.0 0.003 17.5 0.0 8.5 7 0 0 7 7 7 4 HEAT repeat Helicase_C PF00271.26 CAR23600.1 - 2.5e-13 49.6 0.0 5.7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 CAR23600.1 - 1.4e-06 28.5 8.6 1.3 9.3 0.1 7.5 6 3 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 CAR23600.1 - 8.9e-06 26.0 10.8 12 6.5 0.0 8.8 9 1 0 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CAR23600.1 - 0.00028 21.2 0.2 4.8 7.6 0.0 4.7 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region DUF1546 PF07571.8 CAR23600.1 - 0.00089 19.3 0.3 4.4 7.4 0.0 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1546) cwf18 PF08315.7 CAR23601.1 - 8.8e-07 29.4 10.1 3.7e-06 27.4 7.0 2.1 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor Phage_GP20 PF06810.6 CAR23601.1 - 0.058 12.8 6.4 1.2 8.6 1.6 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 UPF0016 PF01169.14 CAR23602.1 - 5.5e-40 135.3 26.6 1e-20 73.6 5.3 2.5 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 DUF204 PF02659.10 CAR23602.1 - 2.8 8.1 11.5 0.32 11.1 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF AAA PF00004.24 CAR23603.1 - 1.6e-32 112.4 0.0 3.3e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR23603.1 - 1.5e-08 35.5 0.0 4.2e-08 34.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CAR23603.1 - 6.2e-08 32.8 0.2 3.1e-07 30.5 0.0 2.3 3 1 0 3 3 1 1 AAA domain AAA_18 PF13238.1 CAR23603.1 - 1.2e-07 32.0 0.0 3e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR23603.1 - 4.1e-07 29.9 0.0 0.00018 21.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR23603.1 - 2e-06 27.8 0.4 0.00018 21.5 0.3 3.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 CAR23603.1 - 2.8e-06 27.0 0.3 1.1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR23603.1 - 4.6e-06 26.2 0.0 1.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 CAR23603.1 - 4.1e-05 22.4 0.1 6.9e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 CAR23603.1 - 5.4e-05 22.3 0.0 8.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 CAR23603.1 - 6.5e-05 22.8 0.1 0.00031 20.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CAR23603.1 - 0.00026 19.9 0.0 0.00052 18.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.9 CAR23603.1 - 0.00062 19.5 0.4 0.011 15.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 CAR23603.1 - 0.00086 19.0 0.3 0.0039 16.8 0.2 2.2 1 1 0 1 1 1 1 NACHT domain AAA_23 PF13476.1 CAR23603.1 - 0.00086 19.6 0.7 0.0027 18.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CAR23603.1 - 0.00087 19.4 0.0 0.0041 17.2 0.0 2.2 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.1 CAR23603.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAR23603.1 - 0.0013 19.0 0.1 0.019 15.2 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.1 CAR23603.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CAR23603.1 - 0.0016 18.0 0.0 0.0045 16.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 CAR23603.1 - 0.0018 18.0 0.1 0.0051 16.5 0.1 1.8 1 1 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 CAR23603.1 - 0.0022 16.9 0.0 0.0044 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activat PF00158.21 CAR23603.1 - 0.0054 16.2 0.1 0.079 12.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CAR23603.1 - 0.0056 16.7 0.1 0.021 14.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain UPF0079 PF02367.12 CAR23603.1 - 0.0071 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 CAR23603.1 - 0.008 15.2 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CAR23603.1 - 0.011 15.6 0.0 0.047 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CAR23603.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CAR23603.1 - 0.014 14.9 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 CAR23603.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 CAR23603.1 - 0.024 14.4 0.0 0.16 11.7 0.0 2.3 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_31 PF13614.1 CAR23603.1 - 0.03 14.2 0.1 0.085 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CAR23603.1 - 0.031 13.9 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.13 CAR23603.1 - 0.035 13.6 0.1 0.09 12.2 0.1 1.8 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CAR23603.1 - 0.038 13.2 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KTI12 PF08433.5 CAR23603.1 - 0.048 12.8 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CAR23603.1 - 0.08 12.0 0.0 0.28 10.2 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin cobW PF02492.14 CAR23603.1 - 0.083 12.3 0.9 0.89 8.9 0.0 2.8 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain tRNA_int_end_N2 PF12928.2 CAR23604.1 - 8.2e-22 76.4 0.0 1.7e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term SH3BGR PF04908.10 CAR23604.1 - 0.043 13.7 0.1 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein BRO1 PF03097.13 CAR23605.1 - 3.6e-93 312.3 10.9 3.6e-93 312.3 7.5 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CAR23605.1 - 5.8e-44 150.2 16.9 3.7e-43 147.5 11.7 2.1 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV Piwi PF02171.12 CAR23605.1 - 0.0061 15.5 0.2 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 Piwi domain MBA1 PF07961.6 CAR23606.1 - 1.4e-100 334.9 1.5 1.6e-100 334.7 1.0 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.16 CAR23606.1 - 0.0082 14.6 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Sec16_C PF12931.2 CAR23607.1 - 6.6e-85 285.2 0.3 1e-84 284.6 0.2 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CAR23607.1 - 3.9e-20 71.9 0.1 1.1e-19 70.5 0.1 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Peptidase_S49_N PF08496.5 CAR23607.1 - 3.6 7.3 11.9 2.2 8.0 1.4 2.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Radical_SAM PF04055.16 CAR23608.1 - 8.3e-16 58.5 0.3 2.4e-15 57.1 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CAR23608.1 - 1.1e-11 44.5 0.0 3.3e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR23608.1 - 0.057 13.5 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Beta_elim_lyase PF01212.16 CAR23609.1 - 2.1e-56 191.1 0.0 2.5e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 CAR23609.1 - 0.13 10.6 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Ceramidase PF05875.7 CAR23610.1 - 8.9e-99 329.8 10.0 1e-98 329.6 6.9 1.0 1 0 0 1 1 1 1 Ceramidase Herpes_pp38 PF04846.8 CAR23610.1 - 0.06 12.6 0.4 0.16 11.2 0.3 1.7 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein DUF2759 PF10958.3 CAR23610.1 - 0.24 11.0 4.0 12 5.5 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) adh_short_C2 PF13561.1 CAR23611.1 - 5.7e-29 101.5 0.1 6.9e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR23611.1 - 1.2e-20 74.0 4.7 1.5e-20 73.7 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR23611.1 - 3.2e-07 30.1 2.2 4.9e-07 29.5 1.5 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CAR23611.1 - 0.013 15.2 0.9 0.031 14.0 0.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SRF-TF PF00319.13 CAR23612.1 - 9.5e-23 79.1 0.0 1.7e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF4557 PF15101.1 CAR23612.1 - 0.0078 16.0 6.6 0.017 14.9 4.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Sigma70_ner PF04546.8 CAR23612.1 - 0.06 12.9 9.4 0.21 11.1 4.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region RAB3GAP2_N PF14655.1 CAR23612.1 - 0.21 10.5 4.2 0.38 9.7 2.9 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 CAR23612.1 - 0.57 8.8 2.8 0.93 8.1 2.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nop14 PF04147.7 CAR23612.1 - 1.3 6.8 18.0 0.01 13.8 3.9 2.0 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 CAR23612.1 - 1.6 7.7 19.6 2.1 7.3 5.5 2.2 2 0 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.7 CAR23612.1 - 1.9 8.1 18.5 3.2 7.3 2.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 CAR23612.1 - 1.9 7.6 18.0 4.1 6.5 6.3 2.2 2 0 0 2 2 2 0 SDA1 OATP PF03137.15 CAR23612.1 - 2.4 6.1 3.9 3.7 5.4 2.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EIIBC-GUT_N PF03612.9 CAR23612.1 - 2.7 7.5 5.6 5.4 6.5 3.9 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.3 CAR23612.1 - 8.7 5.6 12.6 0.27 10.5 4.3 1.7 2 0 0 2 2 2 0 Spt20 family CDC45 PF02724.9 CAR23612.1 - 8.8 4.2 19.4 1.8 6.4 5.7 2.2 2 0 0 2 2 2 0 CDC45-like protein DivIC PF04977.10 CAR23612.1 - 9.9 5.7 15.7 18 4.9 10.9 1.3 1 0 0 1 1 1 0 Septum formation initiator Ribosomal_S6e PF01092.14 CAR23613.1 - 1.5e-62 208.9 0.9 2.6e-62 208.1 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Pyr_redox_2 PF07992.9 CAR23614.1 - 2.1e-41 142.0 1.5 3.2e-41 141.4 1.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CAR23614.1 - 4.1e-36 123.3 1.4 1.6e-35 121.4 0.2 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CAR23614.1 - 1.7e-17 63.5 6.2 4.1e-17 62.3 0.6 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR23614.1 - 1.2e-11 45.0 0.4 1.2e-09 38.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAR23614.1 - 4.1e-06 26.1 0.1 7e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CAR23614.1 - 1.9e-05 23.3 3.4 0.16 10.3 0.4 3.5 3 0 0 3 3 3 3 HI0933-like protein AlaDh_PNT_C PF01262.16 CAR23614.1 - 4.7e-05 23.0 1.8 0.004 16.7 0.0 3.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 CAR23614.1 - 5.2e-05 22.3 0.0 0.0001 21.3 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 CAR23614.1 - 0.00034 19.6 4.1 0.00068 18.5 0.4 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 CAR23614.1 - 0.018 14.2 0.5 4.5 6.3 0.0 3.3 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CAR23614.1 - 0.021 13.7 7.4 0.21 10.4 1.3 2.8 2 1 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.13 CAR23614.1 - 0.2 11.3 0.1 0.2 11.3 0.1 3.0 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 CAR23614.1 - 0.51 9.1 9.2 0.32 9.8 1.7 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase MFS_1 PF07690.11 CAR23615.1 - 8.9e-44 149.6 31.4 8.9e-44 149.6 21.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR23615.1 - 2.4e-17 62.6 26.6 8e-16 57.6 6.5 3.2 2 1 0 3 3 3 3 Sugar (and other) transporter NOG1 PF06858.9 CAR23616.1 - 3.6e-27 94.0 0.4 7.9e-27 92.9 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 CAR23616.1 - 8.7e-27 92.5 1.4 2.6e-26 91.0 1.0 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 CAR23616.1 - 2.9e-16 59.4 0.0 1.4e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR23616.1 - 6e-08 32.1 0.0 1.6e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR23616.1 - 0.0063 16.3 0.0 4.1 7.1 0.0 3.0 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 CAR23616.1 - 0.0071 16.8 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Sec62 PF03839.11 CAR23617.1 - 2.5e-59 200.4 0.0 2.9e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Translocation protein Sec62 FixP_N PF14715.1 CAR23617.1 - 1.2 8.6 4.4 0.42 10.0 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Dynamin_N PF00350.18 CAR23618.1 - 3.5e-16 59.4 0.1 8.9e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CAR23618.1 - 2.3e-10 40.4 0.1 2.4e-09 37.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR23618.1 - 1e-08 34.8 0.5 1.5e-07 31.0 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 CAR23618.1 - 0.0034 17.6 1.1 0.19 12.0 0.0 3.6 4 0 0 4 4 4 1 AAA domain Miro PF08477.8 CAR23618.1 - 0.013 15.9 0.6 0.63 10.5 0.2 3.1 2 1 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 CAR23618.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 CAR23618.1 - 0.088 12.2 0.0 25 4.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Jiraiya PF15038.1 CAR23618.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Jiraiya Abhydrolase_1 PF00561.15 CAR23619.1 - 2.6e-22 79.5 0.0 7.4e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR23619.1 - 2.2e-12 47.3 0.0 4.2e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR23619.1 - 4.6e-07 29.6 0.0 2e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Transglut_core PF01841.14 CAR23620.1 - 2e-11 44.0 0.2 4.9e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 CAR23620.1 - 7.4e-11 41.6 0.4 1.8e-10 40.4 0.1 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain DUF3924 PF13062.1 CAR23620.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) tRNA-synt_1b PF00579.20 CAR23621.1 - 2.6e-79 266.3 0.0 3.5e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 CAR23621.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 S4 domain Romo1 PF10247.4 CAR23622.1 - 2.1e-28 98.3 5.7 2.8e-28 97.8 4.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 MRP-S26 PF14943.1 CAR23623.1 - 0.0025 17.4 0.5 0.24 10.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ribosome subunit S26 DUF2077 PF09850.4 CAR23623.1 - 0.02 14.3 0.5 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF2540 PF10802.3 CAR23623.1 - 0.1 12.2 0.1 2 8.1 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2540) DUF4199 PF13858.1 CAR23623.1 - 0.11 12.4 0.3 0.15 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) 7TM_GPCR_Srab PF10292.4 CAR23623.1 - 0.11 11.1 0.6 0.14 10.7 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF3585 PF12130.3 CAR23623.1 - 0.12 12.1 4.7 0.97 9.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) TMA7 PF09072.5 CAR23623.1 - 0.21 12.0 0.5 0.21 12.0 0.3 2.1 2 0 0 2 2 2 0 Translation machinery associated TMA7 DUF2681 PF10883.3 CAR23623.1 - 0.28 11.4 6.5 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) WD40 PF00400.27 CAR23624.1 - 9.2e-06 25.3 0.7 0.0036 17.1 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat PAXNEB PF05625.6 CAR23625.1 - 2.4e-106 355.6 0.1 2.9e-106 355.3 0.1 1.0 1 0 0 1 1 1 1 PAXNEB protein Lactamase_B_2 PF12706.2 CAR23626.1 - 9.2e-33 113.4 0.3 1.3e-32 112.9 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CAR23626.1 - 1.3e-09 38.0 0.0 2.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CAR23626.1 - 0.0031 17.1 0.3 0.0061 16.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pantoate_transf PF02548.10 CAR23627.1 - 3.6e-94 314.7 0.0 4.3e-94 314.4 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CAR23627.1 - 4.7e-06 25.9 0.0 8.5e-06 25.1 0.0 1.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.11 CAR23628.1 - 7.2e-33 113.7 42.0 9.8e-27 93.5 14.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAR23628.1 - 2.8e-06 26.0 13.5 2.8e-06 26.0 9.3 2.4 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 CAR23628.1 - 0.0011 17.6 8.8 0.0011 17.6 6.1 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter tRNA-synt_2 PF00152.15 CAR23629.1 - 1.8e-115 385.2 0.1 2.3e-115 384.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR23629.1 - 6.3e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CAR23629.1 - 1.1e-05 25.1 0.1 0.0065 16.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 CAR23630.1 - 3.4e-31 105.9 15.0 1.9e-08 33.8 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 CAR23630.1 - 1.8e-06 26.4 0.1 0.014 13.5 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 CAR23630.1 - 2.2e-05 23.4 0.0 0.00011 21.1 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 CAR23630.1 - 9.6e-05 22.1 0.0 0.77 9.4 0.0 3.0 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CAR23630.1 - 0.012 13.9 0.0 0.031 12.5 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain UMP1 PF05348.6 CAR23631.1 - 1.4e-34 118.8 0.0 1.8e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF2217 PF10265.4 CAR23631.1 - 0.015 14.0 0.6 0.016 13.9 0.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) GYF PF02213.11 CAR23632.1 - 1.9e-17 62.5 0.1 4.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 GYF domain Sec66 PF09802.4 CAR23633.1 - 6.2e-75 250.7 1.7 6.9e-75 250.6 1.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Tubulin_3 PF14881.1 CAR23633.1 - 0.057 12.8 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 Tubulin domain NPL4 PF05021.10 CAR23634.1 - 1.2e-114 382.6 0.0 1.7e-114 382.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CAR23634.1 - 1.1e-72 242.4 0.6 1.9e-72 241.7 0.4 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CAR23634.1 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 HSP70 PF00012.15 CAR23635.1 - 1.5e-185 617.5 3.1 1.5e-185 617.5 2.1 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CAR23635.1 - 7.3e-13 47.7 0.4 3e-12 45.7 0.2 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CAR23635.1 - 1.1e-07 31.6 0.6 0.0001 22.1 0.1 3.3 2 1 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.23 CAR23635.1 - 0.014 15.3 0.0 0.074 12.9 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal NLE PF08154.7 CAR23635.1 - 0.11 12.5 0.1 0.56 10.2 0.0 2.3 1 0 0 1 1 1 0 NLE (NUC135) domain Endonuc_Holl PF10107.4 CAR23635.1 - 0.16 11.6 7.0 0.18 11.4 0.1 2.6 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Oxidored-like PF09791.4 CAR23636.1 - 3.9e-26 90.2 3.6 3.9e-26 90.2 2.5 1.7 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Pex24p PF06398.6 CAR23637.1 - 1.7e-42 145.5 4.5 1.9e-42 145.3 3.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpp20 PF12328.3 CAR23638.1 - 3.4e-27 94.8 7.3 2.7e-25 88.6 5.1 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CAR23638.1 - 4.9e-14 51.6 0.4 8.2e-14 50.9 0.2 1.4 1 0 0 1 1 1 1 Alba Nro1 PF12753.2 CAR23638.1 - 0.063 12.2 0.5 0.074 11.9 0.3 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF3896 PF13035.1 CAR23639.1 - 0.016 15.2 1.4 0.021 14.8 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3896) priB_priC PF07445.7 CAR23639.1 - 0.029 13.8 2.9 0.051 13.0 2.0 1.4 1 0 0 1 1 1 0 Primosomal replication protein priB and priC Ureidogly_hydro PF04115.7 CAR23640.1 - 7.9e-47 158.6 0.0 9.6e-47 158.3 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase PDH PF02153.12 CAR23641.1 - 4.4e-08 32.3 0.0 7.3e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 CAR23641.1 - 6.3e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CAR23641.1 - 0.00012 22.4 0.0 0.00024 21.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CAR23641.1 - 0.00012 21.3 0.0 0.00026 20.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CAR23641.1 - 0.0002 20.8 0.0 0.00041 19.8 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CAR23641.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CAR23641.1 - 0.015 14.6 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 CAR23641.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Arf PF00025.16 CAR23643.1 - 1.8e-74 248.7 0.0 2e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR23643.1 - 4.2e-11 42.4 0.0 5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR23643.1 - 5.4e-11 42.0 0.0 6.5e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR23643.1 - 1.6e-10 40.6 0.0 1.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAR23643.1 - 6.5e-10 38.2 0.3 5.5e-06 25.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CAR23643.1 - 1.7e-08 35.0 0.0 2.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CAR23643.1 - 0.00037 19.9 0.0 0.0068 15.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR23643.1 - 0.00095 19.1 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CAR23643.1 - 0.0048 17.1 0.1 0.0094 16.2 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CAR23643.1 - 0.13 11.7 0.1 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.7 CAR23643.1 - 0.14 11.7 0.5 9.5 5.8 0.1 2.2 2 0 0 2 2 2 0 NACHT domain ABC1 PF03109.11 CAR23644.1 - 7.6e-20 71.0 0.0 1.6e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CAR23644.1 - 0.007 16.1 0.0 0.76 9.4 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family GDPD PF03009.12 CAR23645.1 - 2.2e-77 260.0 0.0 4.3e-77 259.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.14 CAR23645.1 - 2.1e-32 113.0 20.2 8.9e-32 110.9 6.5 3.5 3 1 0 3 3 3 1 SPX domain Ank_2 PF12796.2 CAR23645.1 - 2.6e-26 91.7 0.0 7.9e-14 51.7 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 CAR23645.1 - 3.9e-21 73.7 0.4 0.0035 17.0 0.0 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 CAR23645.1 - 6.4e-20 71.1 0.0 4.8e-08 33.3 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAR23645.1 - 3.3e-14 52.5 0.0 0.002 18.3 0.0 5.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR23645.1 - 4.1e-14 51.2 1.2 0.48 10.8 0.0 7.2 5 1 1 6 6 6 3 Ankyrin repeat AMP-binding PF00501.23 CAR23647.1 - 8e-79 264.9 0.1 1.2e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR23647.1 - 0.0018 19.1 0.1 0.0062 17.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.2 CAR23648.1 - 2.2e-26 93.1 0.1 5.1e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR23648.1 - 4.5e-21 75.4 0.1 5.9e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR23648.1 - 6.7e-10 38.8 0.0 1.9e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CAR23648.1 - 7.2e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.8 CAR23648.1 - 0.00033 20.2 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 CAR23648.1 - 0.0099 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) zf-RING_2 PF13639.1 CAR23650.1 - 1.6e-08 34.2 6.7 4.1e-08 32.9 4.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR23650.1 - 5.9e-07 29.5 2.3 1.6e-06 28.1 1.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CAR23650.1 - 6.2e-06 26.0 3.9 1.8e-05 24.5 2.7 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CAR23650.1 - 0.0013 18.5 1.7 0.0027 17.5 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CAR23650.1 - 0.016 15.2 5.4 0.033 14.2 3.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 CAR23650.1 - 0.097 12.7 11.1 0.048 13.6 5.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CAR23650.1 - 0.12 12.3 6.3 0.3 11.1 4.4 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.1 CAR23650.1 - 0.14 11.8 5.7 0.51 10.0 4.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CAR23650.1 - 0.56 9.9 2.0 16 5.3 0.2 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 CAR23650.1 - 0.67 9.6 12.6 0.091 12.4 4.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CAR23650.1 - 1.6 8.3 6.6 44 3.7 4.4 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 CAR23650.1 - 3 7.6 5.3 6.3 6.5 3.7 1.6 1 0 0 1 1 1 0 PHD-finger Glyco_transf_8 PF01501.15 CAR23651.1 - 5.3e-08 32.5 7.9 4.7e-07 29.3 5.4 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CAR23651.1 - 0.0033 16.8 0.3 0.0056 16.0 0.2 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative RPM2 PF08579.6 CAR23651.1 - 0.056 13.5 0.8 25 5.0 0.0 3.7 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) RRM_1 PF00076.17 CAR23652.1 - 6.2e-27 93.0 0.1 1.7e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR23652.1 - 5.1e-19 68.0 0.0 2.9e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR23652.1 - 1.8e-16 59.7 0.1 3.3e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR23652.1 - 0.0011 18.6 0.0 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CAR23652.1 - 0.0088 15.7 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 SAM_decarbox PF01536.11 CAR23653.1 - 2.8e-108 361.5 0.1 3.2e-108 361.3 0.1 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pyridoxal_deC PF00282.14 CAR23654.1 - 1.6e-52 178.2 0.0 2.4e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Coiled PF05710.7 CAR23655.1 - 0.036 14.5 1.9 0.04 14.3 1.3 1.1 1 0 0 1 1 1 0 Coiled coil DUF202 PF02656.10 CAR23655.1 - 1.7 8.9 4.7 1.8 8.8 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Gram_pos_anchor PF00746.16 CAR23655.1 - 6.2 6.7 17.1 2.6 7.9 5.1 2.3 1 1 1 2 2 2 0 Gram positive anchor Recep_L_domain PF01030.19 CAR23656.1 - 3e-10 40.0 9.3 0.0052 16.7 0.0 4.7 1 1 4 5 5 5 4 Receptor L domain LRR_9 PF14580.1 CAR23656.1 - 0.0031 17.0 0.1 0.0079 15.7 0.1 1.7 1 0 0 1 1 1 1 Leucine-rich repeat Bacteriocin_IIc PF10439.4 CAR23656.1 - 0.078 13.1 4.1 1.1 9.4 0.0 3.7 2 1 1 3 3 3 0 Bacteriocin class II with double-glycine leader peptide LRR_8 PF13855.1 CAR23656.1 - 1.4 8.7 17.2 0.11 12.2 2.2 4.8 3 2 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 CAR23656.1 - 3 7.5 24.3 0.3 10.7 4.9 4.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) GLTP PF08718.6 CAR23657.1 - 1.8e-46 157.8 0.1 4e-46 156.7 0.0 1.6 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PCI PF01399.22 CAR23658.1 - 1.3e-07 31.8 0.7 3.2e-06 27.3 0.0 3.0 2 0 0 2 2 2 1 PCI domain PspB PF06667.7 CAR23658.1 - 6.7 6.7 7.2 3.3 7.7 0.5 3.2 2 0 0 2 2 2 0 Phage shock protein B AAA PF00004.24 CAR23659.1 - 2.7e-51 173.2 0.0 2.3e-38 131.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CAR23659.1 - 8.3e-14 51.3 0.0 2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 CAR23659.1 - 8e-10 38.2 2.4 1.2e-09 37.6 0.5 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 CAR23659.1 - 1e-08 35.3 1.3 0.00091 19.3 0.2 3.5 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CAR23659.1 - 1.2e-08 34.5 0.6 0.00089 18.9 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 CAR23659.1 - 7.5e-08 32.5 0.0 0.008 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 CAR23659.1 - 1.9e-07 30.1 0.6 0.014 14.1 0.0 2.4 2 1 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 CAR23659.1 - 2.3e-07 31.6 0.0 0.014 16.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CAR23659.1 - 8e-07 28.6 0.2 0.039 13.3 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CAR23659.1 - 1.8e-06 27.2 0.1 0.0028 16.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CAR23659.1 - 6.8e-06 26.0 0.0 0.068 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CAR23659.1 - 7.2e-06 25.9 0.0 0.024 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CAR23659.1 - 7.8e-06 25.2 0.0 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_5 PF07728.9 CAR23659.1 - 9.1e-06 25.4 0.1 0.0025 17.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CAR23659.1 - 1.8e-05 25.0 0.2 0.014 15.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.9 CAR23659.1 - 5e-05 23.2 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 CAR23659.1 - 6.3e-05 22.7 4.1 0.14 11.8 0.1 3.8 4 1 1 5 5 4 2 NACHT domain RuvB_N PF05496.7 CAR23659.1 - 9.6e-05 21.5 0.1 0.13 11.3 0.1 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 CAR23659.1 - 0.00013 21.5 0.0 0.43 10.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF2075 PF09848.4 CAR23659.1 - 0.00014 20.9 0.0 0.044 12.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 CAR23659.1 - 0.00015 20.7 0.0 0.2 10.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.22 CAR23659.1 - 0.00018 21.8 1.2 0.041 14.1 0.1 2.6 2 0 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 CAR23659.1 - 0.0003 20.4 0.0 0.35 10.4 0.0 3.2 3 0 0 3 3 3 1 Bacterial dnaA protein RNA_helicase PF00910.17 CAR23659.1 - 0.00031 20.8 0.0 0.21 11.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ResIII PF04851.10 CAR23659.1 - 0.00062 19.6 0.0 2 8.2 0.0 2.8 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR23659.1 - 0.001 18.5 0.1 27 4.1 0.0 4.1 3 1 1 4 4 4 0 DEAD/DEAH box helicase AAA_30 PF13604.1 CAR23659.1 - 0.0011 18.6 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 CAR23659.1 - 0.002 17.7 0.1 2.1 8.0 0.0 3.2 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 CAR23659.1 - 0.0033 17.4 0.5 4.8 7.2 0.1 3.5 3 1 0 3 3 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 CAR23659.1 - 0.0034 16.5 0.0 2.4 7.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_11 PF13086.1 CAR23659.1 - 0.0043 16.6 0.1 0.73 9.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CAR23659.1 - 0.012 15.1 2.2 1.1 8.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 CAR23659.1 - 0.012 14.4 0.0 2.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 CAR23659.1 - 0.013 15.8 3.4 1.2 9.3 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.6 CAR23659.1 - 0.017 14.7 0.0 0.092 12.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CAR23659.1 - 0.017 14.2 2.0 0.38 9.8 0.1 2.9 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.1 CAR23659.1 - 0.021 14.2 6.0 2.2 7.6 0.2 3.7 2 2 1 4 4 4 0 AAA domain AAA_29 PF13555.1 CAR23659.1 - 0.041 13.4 0.3 1.4 8.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CAR23659.1 - 0.055 13.1 0.5 10 5.7 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase AAA_28 PF13521.1 CAR23659.1 - 0.075 12.9 0.0 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 CAR23659.1 - 0.15 10.9 0.0 11 4.7 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PRKCSH PF07915.8 CAR23661.1 - 7.9e-06 26.5 0.3 2.1e-05 25.2 0.2 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Bromodomain PF00439.20 CAR23662.1 - 2.7e-18 65.6 0.5 9.8e-18 63.8 0.4 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 CAR23662.1 - 9e-05 22.1 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated UQ_con PF00179.21 CAR23663.1 - 1.4e-51 173.5 0.0 1.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR23663.1 - 5.5e-05 22.9 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CAR23663.1 - 0.00024 20.9 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CAR23663.1 - 0.0096 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain CBF PF03914.12 CAR23664.1 - 3.1e-43 147.0 0.2 3.1e-43 147.0 0.1 3.1 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 CAR23664.1 - 0.0089 16.2 0.2 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein TEA PF01285.13 CAR23665.1 - 2.6e-30 105.9 0.0 4.3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain family FTHFS PF01268.14 CAR23666.1 - 8.3e-258 855.9 3.2 1e-257 855.6 2.2 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CAR23666.1 - 8.8e-68 226.4 0.2 8.8e-68 226.4 0.1 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CAR23666.1 - 2.6e-35 120.9 1.3 7.8e-35 119.4 0.4 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Spiralin PF05215.8 CAR23666.1 - 0.038 13.1 1.7 0.086 11.9 1.2 1.5 1 0 0 1 1 1 0 Spiralin DUF43 PF01861.11 CAR23666.1 - 0.1 11.5 0.0 12 4.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF43 Ribosomal_L19e PF01280.15 CAR23667.1 - 6.4e-59 197.9 12.1 6.4e-59 197.9 8.4 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e DUF2423 PF10338.4 CAR23668.1 - 1.3e-17 63.4 10.2 1.3e-17 63.4 7.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) TSC22 PF01166.13 CAR23668.1 - 0.035 14.0 1.0 0.078 12.9 0.7 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Opi1 PF08618.5 CAR23668.1 - 0.3 9.9 6.6 0.32 9.8 4.6 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DnaG_DnaB_bind PF08278.6 CAR23668.1 - 0.41 10.8 4.4 0.66 10.1 3.1 1.5 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF3552 PF12072.3 CAR23668.1 - 1 8.5 15.4 1.2 8.3 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF972 PF06156.8 CAR23668.1 - 1.7 9.0 9.7 0.79 10.0 4.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spore_III_AF PF09581.5 CAR23668.1 - 2.3 8.0 6.3 2.4 7.9 4.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) IncA PF04156.9 CAR23668.1 - 2.7 7.5 7.7 3 7.3 5.4 1.2 1 0 0 1 1 1 0 IncA protein DUF2203 PF09969.4 CAR23668.1 - 3 8.0 5.4 1.9 8.7 2.6 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ndc1_Nup PF09531.5 CAR23668.1 - 4.9 5.4 5.9 5.4 5.3 4.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF904 PF06005.7 CAR23668.1 - 7.1 6.9 12.9 0.7 10.2 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) RPA_interact_N PF14766.1 CAR23668.1 - 7.5 6.1 7.5 11 5.6 0.1 3.4 4 0 0 4 4 4 0 Replication protein A interacting N-terminal Zn_clus PF00172.13 CAR23670.1 - 5.3e-08 32.6 15.6 1.6e-07 31.1 10.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CAR23670.1 - 5.9e-08 31.9 3.6 1.3e-07 30.8 2.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.22 CAR23671.1 - 2.4e-68 225.8 6.6 4e-24 84.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.24 CAR23673.1 - 2.5e-33 113.4 6.5 7.6e-12 44.6 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CAR23673.1 - 9.5e-27 92.1 8.3 1.9e-09 36.9 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CAR23673.1 - 7.7e-08 31.7 3.0 0.011 15.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CAR23673.1 - 1.5e-06 27.7 1.9 0.23 11.1 0.1 3.6 3 1 0 3 3 3 3 KH domain KH_5 PF13184.1 CAR23673.1 - 0.016 14.9 7.4 1.1 9.0 0.2 3.3 3 0 0 3 3 3 0 NusA-like KH domain Fucokinase PF07959.7 CAR23673.1 - 0.05 12.1 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase GTP_cyclohydro2 PF00925.15 CAR23674.1 - 6.4e-57 191.4 0.1 4.6e-52 175.6 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II CLASP_N PF12348.3 CAR23676.1 - 1.3e-75 253.6 2.6 1e-68 231.0 0.2 2.6 2 0 0 2 2 2 2 CLASP N terminal Pol_alpha_B_N PF08418.5 CAR23677.1 - 7e-60 202.6 0.5 9.7e-60 202.2 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 CAR23677.1 - 3.6e-46 157.0 0.0 5.1e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Anoctamin PF04547.7 CAR23678.1 - 3.9e-49 167.5 25.9 3e-46 158.0 18.0 2.6 1 1 0 1 1 1 1 Calcium-activated chloride channel Ala_racemase_N PF01168.15 CAR23679.1 - 1e-39 136.3 0.0 1.1e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 CAR23680.1 - 3.2e-103 345.8 18.0 4.5e-103 345.3 12.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CAR23680.1 - 9.9e-06 25.8 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 CAR23680.1 - 0.00016 21.5 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.2 CAR23680.1 - 0.0021 17.9 9.4 5.6 6.7 0.1 4.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CAR23680.1 - 0.13 12.4 2.2 3 8.1 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.18 CAR23680.1 - 0.13 12.1 1.0 7.7 6.5 0.2 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Rep_fac_C PF08542.6 CAR23681.1 - 4.3e-21 74.6 0.1 1.1e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CAR23681.1 - 2.4e-12 46.8 0.0 6.3e-12 45.4 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CAR23681.1 - 7.9e-07 29.3 0.0 2.1e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CAR23681.1 - 0.00022 20.0 0.1 0.016 13.8 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CAR23681.1 - 0.023 14.7 0.0 0.073 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CAR23681.1 - 0.033 14.3 0.6 0.18 11.9 0.1 2.4 2 2 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CAR23681.1 - 0.079 13.0 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Nterm_IS4 PF13006.2 CAR23681.1 - 0.11 12.5 0.0 0.8 9.7 0.0 2.3 1 1 1 2 2 2 0 Insertion element 4 transposase N-terminal Ribosomal_L16 PF00252.13 CAR23682.1 - 1.1e-34 119.0 0.1 1.6e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.15 CAR23683.1 - 1.4e-43 148.8 0.1 9.4e-25 87.2 0.0 2.6 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CAR23683.1 - 1e-25 89.7 0.2 3.3e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 CAR23683.1 - 0.098 11.4 3.2 2.7 6.6 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) FAD_binding_1 PF00667.15 CAR23684.1 - 3.8e-29 101.6 0.0 7.2e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CAR23684.1 - 2.2e-18 66.6 0.0 5.5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CAR23684.1 - 1.1e-12 48.4 0.0 2.9e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ATG11 PF10377.4 CAR23685.1 - 1.5e-31 108.9 0.1 1.5e-31 108.9 0.0 3.2 4 0 0 4 4 4 1 Autophagy-related protein 11 DUF2968 PF11180.3 CAR23685.1 - 0.0018 17.6 4.6 0.0018 17.6 3.2 3.8 5 0 0 5 5 5 1 Protein of unknown function (DUF2968) DUF4164 PF13747.1 CAR23685.1 - 0.0084 16.2 4.0 0.0084 16.2 2.7 4.3 3 2 0 3 3 3 1 Domain of unknown function (DUF4164) APG6 PF04111.7 CAR23685.1 - 0.018 14.1 39.1 0.028 13.4 4.9 3.6 3 1 0 3 3 3 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CAR23685.1 - 2.4 7.9 37.5 0.017 14.8 11.0 4.9 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 CAR23685.1 - 9.2 5.3 16.0 0.81 8.8 4.5 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Acetyltransf_1 PF00583.19 CAR23686.1 - 4.2e-20 71.5 0.1 6.5e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR23686.1 - 5.3e-11 42.5 0.1 8.7e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR23686.1 - 4e-10 39.3 0.1 6.2e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CAR23686.1 - 2.4e-09 37.3 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CAR23686.1 - 2.6e-08 33.8 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAR23686.1 - 9.8e-07 29.0 0.0 1.2e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR23686.1 - 9.1e-06 25.5 0.0 2.5e-05 24.1 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAR23686.1 - 0.0002 21.2 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 CAR23686.1 - 0.0017 18.3 0.1 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CAR23686.1 - 0.002 17.7 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CAR23686.1 - 0.025 14.3 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase GNAT_acetyltran PF12746.2 CAR23686.1 - 0.051 12.3 0.0 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 GNAT acetyltransferase PCNA_N PF00705.13 CAR23687.1 - 5.6e-50 168.1 3.6 1.5e-49 166.7 1.2 2.3 2 1 1 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CAR23687.1 - 6.9e-48 161.7 0.4 1.1e-47 161.1 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CAR23687.1 - 0.00098 18.3 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 HMG_box PF00505.14 CAR23688.1 - 3.2e-24 84.9 0.4 5.1e-24 84.3 0.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR23688.1 - 2.1e-17 63.2 0.4 3.2e-17 62.6 0.3 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CAR23688.1 - 0.0053 16.5 0.8 0.0053 16.5 0.5 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 CAR23688.1 - 0.0082 16.3 0.1 0.021 15.0 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) CHDNT PF08073.7 CAR23688.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain zf-Tim10_DDP PF02953.10 CAR23689.1 - 1.4e-14 53.0 0.1 1.7e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TTL PF03133.10 CAR23690.1 - 5e-75 252.1 0.3 8.3e-75 251.4 0.2 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 CAR23690.1 - 8.2e-38 129.6 0.0 1.4e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 CAR23690.1 - 1e-05 25.3 0.0 2.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 CAR23690.1 - 0.0034 16.2 0.0 0.023 13.5 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp RXT2_N PF08595.6 CAR23691.1 - 3.6e-33 114.4 1.0 5e-22 78.3 0.1 2.4 1 1 1 2 2 2 2 RXT2-like, N-terminal 4HBT_2 PF13279.1 CAR23693.1 - 3.2e-08 34.0 0.0 4.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.20 CAR23694.1 - 1.9e-63 214.0 0.0 2.3e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23694.1 - 2.9e-29 101.9 0.0 4.5e-29 101.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23694.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 CAR23694.1 - 0.09 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 CAR23695.1 - 5.2e-25 88.0 0.0 1.5e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 CAR23695.1 - 2.8e-10 39.3 4.3 0.077 13.1 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 CAR23695.1 - 7.4e-07 28.5 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 CAR23695.1 - 1.1e-05 25.6 0.3 0.16 12.3 0.0 3.5 4 1 1 5 5 5 3 HEAT repeats WD40 PF00400.27 CAR23695.1 - 0.0047 16.7 1.2 0.053 13.4 0.1 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat APH PF01636.18 CAR23695.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec8_exocyst PF04048.9 CAR23696.1 - 6.2e-46 155.5 3.0 6.2e-46 155.5 2.0 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CAR23696.1 - 2.6e-06 26.5 1.2 2.6e-06 26.5 0.9 3.0 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) Vps51 PF08700.6 CAR23696.1 - 0.0006 19.5 4.2 0.93 9.3 0.0 5.2 3 2 0 3 3 3 2 Vps51/Vps67 ERCC4 PF02732.10 CAR23697.1 - 0.00013 21.7 0.1 0.00029 20.5 0.1 1.7 1 0 0 1 1 1 1 ERCC4 domain Fes1 PF08609.5 CAR23698.1 - 1.5e-27 95.8 1.7 4.6e-27 94.3 0.5 2.2 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 CAR23698.1 - 1.5e-06 28.4 0.1 0.00017 21.8 0.0 2.9 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 CAR23698.1 - 0.00058 19.7 0.2 0.48 10.6 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat Atx10homo_assoc PF09759.4 CAR23698.1 - 0.0061 16.2 0.1 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 CAR23698.1 - 0.007 16.8 0.4 18 6.0 0.0 4.1 4 0 0 4 4 4 1 HEAT-like repeat V-ATPase_H_C PF11698.3 CAR23698.1 - 0.024 14.5 0.7 0.79 9.6 0.2 2.7 1 1 1 2 2 2 0 V-ATPase subunit H SeqA PF03925.8 CAR23698.1 - 0.027 14.1 0.4 0.072 12.7 0.2 1.7 1 1 0 1 1 1 0 SeqA protein FPL PF09758.4 CAR23698.1 - 0.23 11.2 2.7 7.2 6.3 0.1 2.9 2 1 1 3 3 3 0 Uncharacterised conserved protein UFD1 PF03152.9 CAR23699.1 - 2.3e-06 26.8 0.0 7.8e-05 21.8 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PRP21_like_P PF12230.3 CAR23699.1 - 0.12 11.8 0.1 0.93 8.9 0.0 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein DUF164 PF02591.10 CAR23699.1 - 3.1 7.6 8.0 38 4.2 0.1 3.5 2 1 1 3 3 3 0 Putative zinc ribbon domain zf-RING_3 PF14369.1 CAR23699.1 - 4.5 7.3 12.6 2.2 8.3 0.1 4.1 4 0 0 4 4 4 0 zinc-finger Vps51 PF08700.6 CAR23700.1 - 3.4e-09 36.4 1.4 3.4e-09 36.4 1.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF2524 PF10732.4 CAR23700.1 - 2.2 8.4 10.9 1.4 9.0 0.4 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2524) WD40 PF00400.27 CAR23701.1 - 1.6e-24 84.8 11.6 3.3e-08 33.0 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.6 CAR23701.1 - 5.9e-07 29.0 0.3 1.1e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 CAR23701.1 - 6e-05 22.8 2.2 0.0011 18.7 0.7 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.1 CAR23701.1 - 0.005 15.8 0.0 0.031 13.2 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SdiA-regulated PF06977.6 CAR23701.1 - 0.058 12.3 0.2 2.1 7.2 0.0 3.3 4 0 0 4 4 4 0 SdiA-regulated Tfb4 PF03850.9 CAR23702.1 - 6.4e-104 347.0 0.1 7.5e-104 346.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 CAR23702.1 - 4.1e-05 23.7 0.1 7e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain CRPA PF05745.6 CAR23702.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Mito_carr PF00153.22 CAR23704.1 - 4.2e-60 199.4 2.4 6.7e-21 73.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHODB_Fe-S_bind PF10418.4 CAR23704.1 - 0.078 12.4 0.2 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B CM_2 PF01817.16 CAR23705.1 - 2.5e-10 40.2 0.0 1.4e-05 25.0 0.0 3.3 2 1 0 2 2 2 2 Chorismate mutase type II TetR_C_8 PF14278.1 CAR23705.1 - 0.057 13.8 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region DnaJ PF00226.26 CAR23706.1 - 4.7e-15 55.0 0.1 1.7e-14 53.2 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain TRAPPC9-Trs120 PF08626.6 CAR23706.1 - 0.085 10.1 0.0 0.11 9.8 0.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit dCMP_cyt_deam_1 PF00383.17 CAR23707.1 - 1.5e-21 75.9 0.0 2e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CAR23707.1 - 0.0033 17.2 0.8 0.05 13.4 0.3 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC_N PF08210.6 CAR23707.1 - 0.03 13.9 1.4 0.59 9.7 1.0 2.0 1 1 0 1 1 1 0 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 CAR23707.1 - 0.085 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase UPF0139 PF03669.8 CAR23708.1 - 0.054 13.0 0.2 0.066 12.7 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Vac_ImportDeg PF09783.4 CAR23709.1 - 5.5e-65 218.1 0.0 6.7e-65 217.8 0.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF1212 PF06738.7 CAR23710.1 - 6e-49 166.1 14.6 1.6e-46 158.2 0.7 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CAR23710.1 - 5.2e-26 91.1 11.7 5.2e-26 91.1 8.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) BP28CT PF08146.7 CAR23711.1 - 2.5e-43 147.4 3.7 5.3e-43 146.3 0.9 3.1 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CAR23711.1 - 1.3e-21 76.7 0.5 1.3e-21 76.7 0.4 4.7 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 CAR23711.1 - 0.0015 18.4 1.2 6.4 7.1 0.0 4.8 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CAR23711.1 - 0.0025 18.0 0.6 13 6.1 0.0 4.9 4 1 0 4 4 4 2 HEAT repeats UNC-50 PF05216.8 CAR23712.1 - 8.8e-90 299.9 17.2 9.9e-90 299.7 11.9 1.0 1 0 0 1 1 1 1 UNC-50 family PgaD PF13994.1 CAR23712.1 - 4.4 6.7 7.1 0.3 10.5 1.0 1.8 1 1 0 2 2 2 0 PgaD-like protein PLDc PF00614.17 CAR23715.1 - 1.8e-14 52.9 3.9 2.6e-07 30.2 0.2 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CAR23715.1 - 3.7e-10 39.6 0.0 1.5e-06 27.9 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 CAR23715.1 - 9.4e-07 28.6 4.2 0.0054 16.5 0.2 3.7 3 0 0 3 3 3 2 PX domain GATA PF00320.22 CAR23716.1 - 2.7e-14 52.1 4.7 6e-14 51.0 3.2 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CAR23716.1 - 0.0026 17.0 0.2 0.0045 16.2 0.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Snf7 PF03357.16 CAR23717.1 - 2.6e-15 56.2 18.8 3.2e-15 55.9 13.0 1.2 1 0 0 1 1 1 1 Snf7 CPSase_L_D3 PF02787.14 CAR23717.1 - 0.25 11.1 2.9 0.39 10.4 0.7 2.0 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GrpE PF01025.14 CAR23717.1 - 0.9 9.0 12.7 0.1 12.1 5.3 1.8 1 1 0 2 2 2 0 GrpE Lyase_8_N PF08124.6 CAR23717.1 - 1 8.1 6.2 0.87 8.3 2.7 1.8 1 1 1 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain SurA_N PF09312.6 CAR23717.1 - 1.1 9.0 9.1 2.1 8.2 1.1 3.0 1 1 0 2 2 2 0 SurA N-terminal domain Aldo_ket_red PF00248.16 CAR23718.1 - 9.6e-53 178.8 0.0 1.2e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cpn60_TCP1 PF00118.19 CAR23719.1 - 6.7e-144 480.1 3.5 7.8e-144 479.8 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 CAR23720.1 - 6.4e-32 108.2 8.9 2.8e-08 33.3 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CAR23720.1 - 2.3e-08 32.6 6.5 0.00019 19.7 0.0 4.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Mdv1 PF11542.3 CAR23720.1 - 1.4e-06 28.0 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial division protein 1 BBS2_Mid PF14783.1 CAR23720.1 - 0.0025 17.5 0.5 0.15 11.8 0.0 3.2 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF3249 PF11615.3 CAR23720.1 - 0.026 14.2 0.1 6.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3249) DASH_Spc34 PF08657.5 CAR23721.1 - 9.6e-59 199.1 2.0 1.2e-58 198.7 1.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Spc34 TetR_C_4 PF08359.6 CAR23721.1 - 0.067 13.1 0.2 0.35 10.8 0.0 2.3 1 1 1 2 2 2 0 YsiA-like protein, C-terminal region THOC7 PF05615.8 CAR23721.1 - 0.16 12.2 8.4 0.045 14.0 2.4 2.4 2 1 1 3 3 3 0 Tho complex subunit 7 Occludin_ELL PF07303.8 CAR23721.1 - 0.25 12.1 5.5 0.24 12.1 0.7 2.3 2 0 0 2 2 2 0 Occludin homology domain IncA PF04156.9 CAR23721.1 - 8.4 5.9 10.8 1.9 8.0 5.0 1.8 1 1 0 2 2 2 0 IncA protein DUF919 PF06034.6 CAR23721.1 - 9.8 5.8 8.5 0.31 10.6 0.4 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Peptidase_M22 PF00814.20 CAR23722.1 - 3.6e-84 282.4 0.0 4.3e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 CAR23722.1 - 0.042 12.9 0.1 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase AA_permease PF00324.16 CAR23723.1 - 5.4e-150 499.8 41.0 6.5e-150 499.6 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23723.1 - 3.2e-41 141.2 42.9 4.1e-41 140.9 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease SET PF00856.23 CAR23724.1 - 1.2e-08 35.4 0.0 4.9e-05 23.6 0.0 3.7 3 1 1 4 4 4 2 SET domain CENP-T PF15511.1 CAR23724.1 - 0.005 16.1 5.9 0.005 16.1 4.1 2.1 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T DUF2201_N PF13203.1 CAR23724.1 - 0.83 8.7 8.4 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain Glypican PF01153.14 CAR23724.1 - 8.6 4.8 6.8 13 4.1 4.7 1.2 1 0 0 1 1 1 0 Glypican Ribosomal_L4 PF00573.17 CAR23725.1 - 7.8e-47 159.1 2.6 1.1e-46 158.6 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CAR23725.1 - 3.7e-31 106.8 2.5 2.1e-30 104.4 0.5 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Methyltransf_31 PF13847.1 CAR23726.1 - 3.3e-13 49.4 0.0 8.9e-13 48.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CAR23726.1 - 9.1e-12 44.6 0.0 1.8e-11 43.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CAR23726.1 - 1.5e-10 41.6 0.0 5.3e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR23726.1 - 3.5e-10 39.9 0.0 8.2e-10 38.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR23726.1 - 2.3e-07 30.7 0.0 3.7e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR23726.1 - 2.3e-07 31.1 0.0 6.7e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 CAR23726.1 - 6.9e-07 28.2 0.0 9.9e-07 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 CAR23726.1 - 3.7e-06 26.4 0.0 6.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 CAR23726.1 - 3.9e-06 26.0 0.1 4.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.1 CAR23726.1 - 1.5e-05 25.3 0.0 6e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CAR23726.1 - 2.3e-05 23.5 0.0 3.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 CAR23726.1 - 0.00011 22.2 0.0 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 CAR23726.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 CAR23726.1 - 0.00096 19.5 0.0 0.0026 18.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CAR23726.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CAR23726.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 CAR23726.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 CAR23726.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 CAR23726.1 - 0.11 13.3 0.0 0.23 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DER1 PF04511.10 CAR23728.1 - 0.0067 15.9 9.8 0.011 15.2 6.8 1.3 1 0 0 1 1 1 1 Der1-like family Prefoldin PF02996.12 CAR23729.1 - 2.6e-33 114.1 2.8 3.7e-33 113.7 1.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4206 PF13901.1 CAR23729.1 - 0.011 15.3 0.6 0.024 14.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Prefoldin_2 PF01920.15 CAR23729.1 - 0.087 12.5 6.4 0.13 12.0 0.7 2.5 1 1 1 2 2 2 0 Prefoldin subunit DUF4358 PF14270.1 CAR23729.1 - 0.1 12.4 0.5 0.19 11.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Ly49 PF08391.5 CAR23729.1 - 0.46 10.6 5.9 7 6.8 0.2 2.3 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region ABC_tran PF00005.22 CAR23730.1 - 1.3e-52 177.7 0.1 1.2e-26 93.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 CAR23730.1 - 2.5e-41 141.1 37.6 5.4e-26 91.0 8.7 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 CAR23730.1 - 9.1e-18 65.2 5.8 0.00013 22.0 0.1 4.3 3 1 1 4 4 4 4 AAA domain AAA_17 PF13207.1 CAR23730.1 - 4.8e-10 40.3 0.1 0.0017 19.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 CAR23730.1 - 5.2e-10 38.7 0.3 0.0005 19.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAR23730.1 - 8.5e-10 38.9 0.1 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 CAR23730.1 - 5.7e-09 36.3 0.1 0.0049 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CAR23730.1 - 1.3e-08 34.3 0.0 0.0039 16.4 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CAR23730.1 - 3.2e-08 33.0 0.8 0.42 9.5 0.0 4.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CAR23730.1 - 7.1e-08 32.6 0.0 0.0071 16.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAR23730.1 - 9.3e-08 31.4 1.0 0.011 15.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CAR23730.1 - 2.1e-07 30.5 0.0 0.0019 17.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 CAR23730.1 - 5.9e-07 30.0 1.6 0.008 16.5 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CAR23730.1 - 7.9e-07 29.1 0.0 0.0033 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CAR23730.1 - 9.9e-07 28.7 0.1 0.052 13.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 CAR23730.1 - 5.1e-06 26.2 0.0 0.0088 15.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain T2SE PF00437.15 CAR23730.1 - 5.4e-06 25.4 0.4 0.011 14.6 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 CAR23730.1 - 9.1e-06 25.3 3.5 0.064 12.6 0.3 3.0 3 0 0 3 3 3 2 AAA-like domain RNA_helicase PF00910.17 CAR23730.1 - 1.3e-05 25.2 0.1 0.1 12.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 CAR23730.1 - 4.7e-05 23.1 1.2 0.035 13.8 0.3 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CAR23730.1 - 7.3e-05 22.6 0.0 0.36 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CAR23730.1 - 0.00013 21.6 0.0 0.039 13.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CAR23730.1 - 0.00016 21.2 0.3 0.063 12.7 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Arch_ATPase PF01637.13 CAR23730.1 - 0.00021 21.0 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_33 PF13671.1 CAR23730.1 - 0.00022 21.0 0.0 0.64 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.9 CAR23730.1 - 0.00083 18.4 0.0 0.56 9.1 0.0 2.2 2 0 0 2 2 2 2 KAP family P-loop domain AAA_30 PF13604.1 CAR23730.1 - 0.0009 18.8 0.0 0.84 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CAR23730.1 - 0.001 19.5 0.0 0.83 10.1 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein ABC_ATPase PF09818.4 CAR23730.1 - 0.0011 17.6 0.3 0.03 12.8 0.1 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class cobW PF02492.14 CAR23730.1 - 0.0014 18.0 1.8 0.54 9.6 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CAR23730.1 - 0.0015 18.2 0.3 3 7.5 0.0 3.2 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.17 CAR23730.1 - 0.0026 16.6 0.0 0.95 8.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 CAR23730.1 - 0.0028 17.8 0.0 2.3 8.4 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 CAR23730.1 - 0.0029 17.1 0.1 0.37 10.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 CAR23730.1 - 0.0042 16.5 0.1 0.65 9.4 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CAR23730.1 - 0.0046 16.2 0.4 2.3 7.3 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 CAR23730.1 - 0.0048 16.2 0.0 1.1 8.5 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase ArgK PF03308.11 CAR23730.1 - 0.0049 15.6 0.4 0.19 10.4 0.1 2.2 2 0 0 2 2 2 1 ArgK protein Pox_A32 PF04665.7 CAR23730.1 - 0.0055 16.0 3.2 0.057 12.7 0.1 2.9 3 0 0 3 3 3 1 Poxvirus A32 protein Rad17 PF03215.10 CAR23730.1 - 0.0063 15.2 0.1 0.41 9.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 CAR23730.1 - 0.01 15.4 0.5 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CAR23730.1 - 0.014 15.1 0.4 2.8 7.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 CAR23730.1 - 0.018 14.5 0.8 6 6.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.10 CAR23730.1 - 0.022 13.4 0.3 0.11 11.1 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein Septin PF00735.13 CAR23730.1 - 0.025 13.6 0.1 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Septin GBP PF02263.14 CAR23730.1 - 0.03 13.3 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain GTP_EFTU PF00009.22 CAR23730.1 - 0.03 13.7 0.1 21 4.5 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CAR23730.1 - 0.039 13.3 1.1 0.2 11.0 0.3 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.15 CAR23730.1 - 0.041 13.5 0.8 8.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase SbcCD_C PF13558.1 CAR23730.1 - 0.042 13.7 0.6 4.8 7.1 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CAR23730.1 - 0.043 13.6 8.1 2.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 CAR23730.1 - 0.044 12.8 0.3 7.4 5.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin KaiC PF06745.8 CAR23730.1 - 0.067 12.3 0.2 0.68 9.0 0.0 2.5 2 0 0 2 2 2 0 KaiC RuvB_N PF05496.7 CAR23730.1 - 0.084 11.9 0.1 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF3987 PF13148.1 CAR23730.1 - 0.15 10.6 0.1 12 4.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) UPF0079 PF02367.12 CAR23730.1 - 0.17 11.5 0.0 0.96 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2791 PF10923.3 CAR23730.1 - 0.24 9.9 0.0 8.3 4.8 0.0 2.1 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Dynamin_N PF00350.18 CAR23730.1 - 0.29 10.9 5.4 7 6.4 0.2 2.5 2 0 0 2 2 2 0 Dynamin family CYSTM PF12734.2 CAR23732.1 - 4.5e-06 26.6 49.6 46 4.2 34.4 4.6 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance DUF4591 PF15261.1 CAR23732.1 - 0.075 13.2 5.2 0.11 12.7 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) UAA PF08449.6 CAR23733.1 - 6.2e-11 41.7 17.2 9.4e-11 41.1 11.9 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CAR23733.1 - 2.3e-09 36.7 1.3 4.3e-09 35.8 0.9 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CAR23733.1 - 2e-07 31.0 26.7 4e-06 26.8 3.4 3.2 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CAR23733.1 - 0.00012 22.2 7.1 0.00012 22.2 4.9 3.7 2 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 CAR23733.1 - 0.15 11.7 23.3 0.5 10.0 2.5 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2976 PF11190.3 CAR23733.1 - 1 8.9 11.5 3.9 7.0 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2976) zf-RING_5 PF14634.1 CAR23734.1 - 0.0017 18.0 0.6 0.0041 16.8 0.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR23734.1 - 0.0022 17.9 0.1 0.0058 16.6 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR23734.1 - 0.016 14.8 0.0 0.044 13.4 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR23734.1 - 0.046 13.5 0.4 0.15 12.0 0.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING IBR PF01485.16 CAR23734.1 - 0.42 10.5 6.1 6.3 6.7 1.1 2.5 1 1 1 2 2 2 0 IBR domain Fibrillarin PF01269.12 CAR23735.1 - 6e-108 359.0 0.0 7.3e-108 358.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CAR23735.1 - 5.9e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CAR23735.1 - 0.037 13.5 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Steroid_dh PF02544.11 CAR23737.1 - 2.1e-29 102.2 9.6 2.1e-29 102.2 6.7 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Pkinase PF00069.20 CAR23738.1 - 6.2e-41 140.2 0.0 3.9e-22 78.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23738.1 - 1.6e-15 56.9 0.0 1.3e-10 40.8 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR23738.1 - 0.0018 17.2 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CAR23738.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 CAR23739.1 - 1.7e-25 89.8 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Amidohydro_1 PF01979.15 CAR23740.1 - 1.5e-30 107.0 0.0 1.1e-17 64.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CAR23740.1 - 1.1e-23 84.7 0.0 8.5e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CAR23740.1 - 2.1e-09 37.0 0.6 4.3e-09 36.0 0.5 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CAR23740.1 - 1.4e-08 34.4 0.1 3.2e-05 23.3 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family HEAT_EZ PF13513.1 CAR23741.1 - 2.7e-18 65.8 0.0 8.6e-11 42.0 0.0 7.0 7 1 0 7 7 7 2 HEAT-like repeat HEAT PF02985.17 CAR23741.1 - 5.8e-18 63.3 6.1 0.013 15.5 0.0 9.4 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.1 CAR23741.1 - 2.6e-13 50.0 0.0 2.9e-06 27.4 0.0 5.5 4 3 3 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.2 CAR23741.1 - 4.3e-05 23.8 0.1 0.035 14.4 0.0 4.0 3 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF3201 PF11447.3 CAR23741.1 - 0.099 12.0 0.3 0.93 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3201) Glyco_hydro_42C PF08533.5 CAR23741.1 - 0.16 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain SH3_1 PF00018.23 CAR23742.1 - 4.6e-08 32.3 0.0 1.2e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR23742.1 - 6e-06 25.7 0.0 1.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Stress-antifung PF01657.12 CAR23742.1 - 0.083 13.2 1.0 2.4 8.5 0.7 2.6 2 0 0 2 2 2 0 Salt stress response/antifungal SAICAR_synt PF01259.13 CAR23743.1 - 1.4e-100 335.5 0.0 1.6e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase UPF0086 PF01868.11 CAR23743.1 - 0.079 12.6 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function UPF0086 Pkinase PF00069.20 CAR23744.1 - 4.2e-63 212.9 0.0 6.3e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23744.1 - 3e-35 121.5 0.0 2.3e-20 72.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR23744.1 - 0.002 17.1 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CAR23745.1 - 1.3e-70 237.5 0.1 2.2e-70 236.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23745.1 - 2.3e-51 174.3 0.0 4.2e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23745.1 - 1.1e-05 24.5 0.1 3.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAR23745.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Oxysterol_BP PF01237.13 CAR23746.1 - 1.2e-131 438.4 2.1 1.2e-131 438.4 1.4 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 CAR23746.1 - 9.7e-12 45.0 0.0 3.8e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAR23746.1 - 1.2e-11 44.4 0.1 0.00029 20.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAR23746.1 - 4.2e-10 39.8 0.1 7.2e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CAR23746.1 - 1.5e-09 37.1 0.1 0.00031 20.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.1 CAR23746.1 - 4.4e-08 33.0 0.1 1.3e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CAR23746.1 - 4.5e-07 30.0 0.8 3.5e-06 27.1 0.6 2.6 1 1 0 1 1 1 1 PH domain Ank_3 PF13606.1 CAR23746.1 - 4.7e-07 29.4 0.0 0.005 16.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat PH_11 PF15413.1 CAR23746.1 - 3.7e-06 27.1 0.3 3.7e-06 27.1 0.2 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain HMG_CoA_synt_C PF08540.5 CAR23747.1 - 1.1e-105 353.1 3.9 1.5e-105 352.7 2.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 CAR23747.1 - 2.1e-95 317.1 0.2 3.2e-95 316.5 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RPM2 PF08579.6 CAR23748.1 - 7.5e-46 155.1 0.2 7.5e-46 155.1 0.2 3.3 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.1 CAR23748.1 - 5.4e-05 23.0 0.8 1.5 8.8 0.0 5.7 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.1 CAR23748.1 - 0.0078 16.4 0.1 23 5.6 0.0 4.8 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 CAR23748.1 - 0.013 15.4 0.0 0.63 10.1 0.0 3.8 3 0 0 3 3 3 0 PPR repeat Ribosomal_L2 PF00181.18 CAR23748.1 - 0.036 14.0 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain Maelstrom PF13017.1 CAR23749.1 - 0.13 11.6 0.1 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 piRNA pathway germ-plasm component Ish1 PF10281.4 CAR23750.1 - 2.2e-42 142.7 42.9 1.3e-08 34.7 2.1 8.0 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 CAR23750.1 - 1.1e-05 24.8 1.9 0.078 12.5 0.1 3.5 3 0 0 3 3 3 2 HeH/LEM domain SAP PF02037.22 CAR23750.1 - 0.00025 20.4 0.5 1 8.9 0.0 4.5 4 0 0 4 4 4 1 SAP domain SAP30_Sin3_bdg PF13867.1 CAR23750.1 - 0.0024 17.6 2.2 1.3 8.9 0.0 3.8 4 0 0 4 4 4 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF883 PF05957.8 CAR23750.1 - 0.15 12.5 56.0 0.22 11.9 3.8 8.2 5 1 3 8 8 8 0 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.11 CAR23750.1 - 7.4 6.5 132.4 1.2 9.1 8.1 9.0 4 1 5 10 10 10 0 Late embryogenesis abundant protein Rtf2 PF04641.7 CAR23751.1 - 9.1e-34 116.8 0.3 2.5e-33 115.3 0.2 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 CAR23751.1 - 0.0069 15.8 0.3 3.9 7.0 0.3 2.7 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 CAR23751.1 - 0.015 14.7 0.4 0.037 13.5 0.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.9 CAR23751.1 - 0.042 13.3 0.1 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif UPF0547 PF10571.4 CAR23751.1 - 0.043 13.5 2.0 5.2 6.8 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_5 PF14634.1 CAR23751.1 - 0.048 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CAR23751.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 CAR23751.1 - 0.29 10.8 1.6 0.52 10.0 1.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 CAR23752.1 - 1.9e-07 30.5 16.7 0.00026 20.5 0.7 3.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CAR23752.1 - 9.2e-06 25.4 0.1 1.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR23752.1 - 0.00037 20.0 0.1 0.00076 19.0 0.0 1.6 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 CAR23753.1 - 2.6e-60 202.9 0.0 3.3e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR23753.1 - 4e-09 35.6 0.8 7e-09 34.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Utp14 PF04615.8 CAR23754.1 - 2.5e-207 690.5 81.5 2.5e-207 690.5 56.5 2.1 1 1 1 2 2 2 1 Utp14 protein Prefoldin PF02996.12 CAR23755.1 - 1e-26 92.9 3.9 1.3e-26 92.5 2.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4110 PF13422.1 CAR23755.1 - 0.59 10.0 3.4 0.67 9.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) Rad10 PF03834.9 CAR23756.1 - 1.8e-27 94.7 0.5 3.4e-27 93.9 0.4 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Asn_synthase PF00733.16 CAR23757.1 - 5.7e-45 153.8 0.0 8.9e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CAR23757.1 - 2.6e-11 43.3 0.1 3.6e-09 36.4 0.0 3.0 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CAR23757.1 - 4.2e-07 29.9 0.0 3.1e-06 27.1 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CAR23757.1 - 0.0045 16.2 0.0 0.0087 15.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein VPS9 PF02204.13 CAR23758.1 - 4.4e-26 90.9 0.0 7.7e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CAR23758.1 - 3.8e-06 26.2 0.0 6.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain ERO1 PF04137.10 CAR23759.1 - 7.6e-123 410.0 1.5 7.6e-123 410.0 1.0 1.5 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RAI16-like PF10257.4 CAR23759.1 - 0.0083 15.0 0.6 2.2 7.0 0.1 2.6 2 1 0 2 2 2 2 Retinoic acid induced 16-like protein DUF2800 PF10926.3 CAR23759.1 - 0.016 14.3 0.1 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) TFIID-18kDa PF02269.11 CAR23760.1 - 1e-29 102.1 0.1 1.7e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 CAR23760.1 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Fungal_trans_2 PF11951.3 CAR23761.1 - 1.2e-104 350.0 0.1 1.6e-104 349.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR23761.1 - 1e-12 47.7 6.5 2.4e-12 46.5 4.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M85 PF13678.1 CAR23761.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 NFkB-p65-degrading zinc protease GFO_IDH_MocA PF01408.17 CAR23762.1 - 2.4e-23 82.9 0.2 5.3e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CAR23762.1 - 2.9e-08 33.5 0.0 5.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.15 CAR23762.1 - 0.083 12.9 0.2 0.2 11.7 0.0 1.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_6 PF00970.19 CAR23763.1 - 4.8e-10 39.4 0.0 8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 CAR23763.1 - 5.7e-08 33.0 0.0 2.1e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.16 CAR23763.1 - 1e-06 29.2 0.0 2.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 CAR23763.1 - 0.0029 17.2 0.1 0.0057 16.3 0.1 1.5 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 CAR23763.1 - 0.11 12.3 0.2 0.28 11.0 0.1 1.8 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Cys_Met_Meta_PP PF01053.15 CAR23764.1 - 2.4e-62 210.4 0.0 9.8e-62 208.4 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CAR23764.1 - 0.0013 17.5 0.0 0.0031 16.3 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V gag_pre-integrs PF13976.1 CAR23764.1 - 0.01 15.4 0.0 0.033 13.8 0.0 1.8 2 0 0 2 2 2 0 GAG-pre-integrase domain GDC-P PF02347.11 CAR23764.1 - 0.052 12.2 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein MFS_1 PF07690.11 CAR23765.1 - 5e-27 94.5 19.9 5e-27 94.5 13.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CAR23765.1 - 0.0029 17.3 1.8 0.02 14.6 0.0 2.9 3 0 0 3 3 3 1 MFS_1 like family DUF1228 PF06779.9 CAR23765.1 - 0.011 15.7 0.3 0.011 15.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) DUF2207 PF09972.4 CAR23765.1 - 2.8 6.4 7.1 3.5 6.0 0.2 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Sulfatase PF00884.18 CAR23766.1 - 2.5e-66 223.9 0.0 3.3e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 CAR23766.1 - 0.00015 20.3 0.0 0.00018 20.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 CAR23766.1 - 0.0013 18.1 0.0 0.004 16.5 0.0 1.8 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Macoilin PF09726.4 CAR23767.1 - 1.7 6.8 15.9 1.9 6.6 11.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 CAR23767.1 - 2.7 6.4 13.6 3.2 6.1 9.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 AF-4 PF05110.8 CAR23767.1 - 5.4 4.7 20.4 5.4 4.7 14.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAD_binding_8 PF08022.7 CAR23769.1 - 5.8e-22 77.5 0.1 1.8e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 CAR23769.1 - 4.5e-19 68.7 8.7 1.6e-18 67.0 6.1 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CAR23769.1 - 3.1e-14 53.1 0.0 6.7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 CAR23769.1 - 0.0047 17.4 0.0 0.072 13.6 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain mIF3 PF14877.1 CAR23769.1 - 0.12 11.7 0.2 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor MFS_1 PF07690.11 CAR23770.1 - 1.1e-44 152.6 32.8 8.1e-43 146.4 24.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR23770.1 - 1.8e-16 59.7 14.4 1.8e-16 59.7 10.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter NPIP PF06409.6 CAR23770.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) DoxX_3 PF13781.1 CAR23770.1 - 0.22 11.9 8.1 0.66 10.3 0.3 3.5 3 0 0 3 3 3 0 DoxX-like family Spy1 PF11357.3 CAR23771.1 - 0.024 14.6 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Cell cycle regulatory protein SLAC1 PF03595.12 CAR23772.1 - 6.3e-65 218.9 25.8 7.3e-65 218.7 17.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4491 PF14898.1 CAR23772.1 - 0.085 13.0 0.0 0.085 13.0 0.0 4.8 6 1 0 6 6 6 0 Domain of unknown function (DUF4491) GST_N PF02798.15 CAR23773.1 - 1.7e-13 50.5 0.0 2.9e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CAR23773.1 - 1.1e-10 41.3 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CAR23773.1 - 7.7e-07 29.2 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CAR23773.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CAR23773.1 - 1.2e-05 25.7 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAR23773.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RTBV_P12 PF06361.6 CAR23773.1 - 0.063 13.5 0.3 0.35 11.1 0.1 2.0 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Scm3 PF10384.4 CAR23773.1 - 0.1 12.1 0.2 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Centromere protein Scm3 MFS_1 PF07690.11 CAR23774.1 - 7.1e-33 113.7 54.2 4.4e-25 88.1 26.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR23774.1 - 3e-07 29.3 18.8 9.9e-07 27.6 0.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 CAR23774.1 - 0.00011 21.8 1.3 0.00027 20.6 0.4 2.1 2 0 0 2 2 2 1 MFS_1 like family Aldo_ket_red PF00248.16 CAR23775.1 - 4.1e-69 232.5 0.0 4.7e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_1 PF01979.15 CAR23776.1 - 9e-34 117.5 0.3 1.6e-33 116.8 0.2 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CAR23776.1 - 2.1e-15 57.5 0.2 7.8e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CAR23776.1 - 2.6e-14 52.7 0.0 1.2e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CAR23776.1 - 2.4e-12 46.7 1.7 9.6e-10 38.2 0.0 2.3 1 1 1 2 2 2 2 Amidohydrolase family Sugar_tr PF00083.19 CAR23777.1 - 1.7e-86 290.6 20.6 1.9e-86 290.4 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR23777.1 - 2.4e-10 39.6 26.5 6.1e-10 38.3 17.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CAR23777.1 - 3.7e-08 32.1 16.2 1.1e-06 27.2 0.5 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein CENP-K PF11802.3 CAR23777.1 - 0.014 14.6 0.6 0.022 13.9 0.4 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Alpha-amylase PF00128.19 CAR23778.1 - 8e-105 350.7 0.1 1.4e-104 349.8 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 CAR23778.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme ABC2_membrane PF01061.19 CAR23779.1 - 1.9e-42 144.7 21.3 1.9e-42 144.7 14.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 CAR23779.1 - 0.0011 18.5 0.2 0.0011 18.5 0.1 2.4 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 CAR23779.1 - 0.064 12.2 21.6 0.72 8.8 15.9 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Methyltransf_11 PF08241.7 CAR23780.1 - 2.8e-10 40.5 0.0 6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR23780.1 - 6.2e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR23780.1 - 1.3e-08 35.1 0.0 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR23780.1 - 4.7e-08 32.7 0.0 6.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR23780.1 - 1e-07 32.5 0.0 1.8e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR23780.1 - 6.9e-06 26.3 0.0 1.5e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR23780.1 - 0.00023 21.1 0.0 0.00065 19.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR23780.1 - 0.00024 20.3 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CAR23780.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Pectate_lyase PF03211.8 CAR23781.1 - 1.1e-58 198.1 3.5 1.3e-58 197.9 2.4 1.0 1 0 0 1 1 1 1 Pectate lyase DUF3494 PF11999.3 CAR23781.1 - 0.012 15.2 1.4 0.02 14.5 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) Vel1p PF10339.4 CAR23782.1 - 1.1e-112 374.0 2.7 1.3e-112 373.8 1.9 1.0 1 0 0 1 1 1 1 Yeast-specific zinc responsive Homeobox PF00046.24 CAR23783.1 - 7.8e-07 28.6 0.2 1.5e-06 27.7 0.1 1.5 2 0 0 2 2 2 1 Homeobox domain DHO_dh PF01180.16 CAR23785.1 - 1.3e-91 306.6 0.0 1.4e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CAR23785.1 - 2.4e-06 26.6 0.0 0.00026 19.9 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase DUF885 PF05960.6 CAR23785.1 - 0.012 14.8 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) PcrB PF01884.12 CAR23785.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 PcrB family Mito_carr PF00153.22 CAR23786.1 - 2e-58 194.0 2.2 2.7e-19 68.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Staph_haemo PF05480.6 CAR23787.1 - 0.074 12.7 0.4 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Staphylococcus haemolytic protein MAT_Alpha1 PF04769.7 CAR23788.1 - 5.4e-07 29.1 6.0 5.5e-07 29.1 1.0 2.2 1 1 1 2 2 2 2 Mating-type protein MAT alpha 1 Homeobox_KN PF05920.6 CAR23789.1 - 5.4e-12 45.2 2.4 7.4e-12 44.7 0.8 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CAR23789.1 - 1e-08 34.6 3.9 1.4e-08 34.2 2.7 1.2 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CAR23789.1 - 0.019 13.9 0.1 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PALP PF00291.20 CAR23790.1 - 6.6e-59 199.6 0.0 7.6e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 CAR23790.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain RcsC PF09456.5 CAR23791.1 - 0.098 12.3 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) MRC1 PF09444.5 CAR23792.1 - 5.3e-41 140.3 11.7 5.3e-41 140.3 8.1 4.4 4 2 0 4 4 4 1 MRC1-like domain KH_1 PF00013.24 CAR23793.1 - 0.0018 17.8 0.0 0.0067 16.0 0.0 1.9 1 1 1 2 2 2 1 KH domain KH_3 PF13014.1 CAR23793.1 - 0.035 13.7 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 KH domain DUF883 PF05957.8 CAR23793.1 - 0.36 11.2 3.3 0.74 10.2 2.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DHquinase_II PF01220.14 CAR23794.1 - 0.066 12.5 0.5 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Dehydroquinase class II DUF4628 PF15429.1 CAR23794.1 - 0.067 12.6 2.8 0.075 12.4 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) MRP-S31 PF15433.1 CAR23794.1 - 0.081 12.3 7.4 0.089 12.1 5.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF543 PF04418.7 CAR23795.1 - 6.8e-29 99.6 0.3 7.6e-29 99.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) NADH_dh_m_C1 PF15088.1 CAR23795.1 - 0.42 10.1 3.7 5.1 6.6 0.1 2.2 1 1 1 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial PEX11 PF05648.9 CAR23796.1 - 0.00064 19.0 0.6 0.00095 18.4 0.4 1.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) 2OG-FeII_Oxy_2 PF13532.1 CAR23797.1 - 3.2e-19 69.5 0.0 4.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_ribbon_recom PF13408.1 CAR23797.1 - 0.068 13.4 2.1 0.13 12.5 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Voltage_CLC PF00654.15 CAR23799.1 - 9.3e-85 284.7 22.8 9.3e-85 284.7 15.8 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel MT-A70 PF05063.9 CAR23800.1 - 2.6e-13 49.9 0.0 4.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 MT-A70 CMAS PF02353.15 CAR23801.1 - 3.1e-61 206.8 0.4 3.8e-61 206.5 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CAR23801.1 - 1.5e-12 47.5 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR23801.1 - 1.1e-07 32.1 0.0 2.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR23801.1 - 1e-06 29.1 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR23801.1 - 2.2e-06 27.3 0.0 3.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR23801.1 - 5.3e-06 26.9 0.0 1.4e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR23801.1 - 0.0017 18.6 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain COX7C PF02935.11 CAR23801.1 - 0.0032 17.2 0.6 0.0068 16.1 0.4 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc MTS PF05175.9 CAR23801.1 - 0.0049 16.2 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 CAR23801.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CAR23801.1 - 0.011 15.7 0.0 0.038 14.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CAR23801.1 - 0.027 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 CAR23801.1 - 0.041 13.4 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 CAR23801.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4049 PF13258.1 CAR23801.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Spb1_C PF07780.7 CAR23802.1 - 1.5e-76 256.6 23.1 1.5e-76 256.6 16.0 3.7 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 CAR23802.1 - 9.4e-54 181.2 14.9 9.4e-54 181.2 10.4 5.1 4 1 0 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 CAR23802.1 - 5.4e-53 179.6 0.8 1.8e-52 177.9 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase PIG-X PF08320.7 CAR23803.1 - 1.1e-46 158.7 0.0 1.5e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 UCR_14kD PF02271.11 CAR23805.1 - 6e-43 144.8 0.2 6.9e-43 144.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ATP_transf PF09830.4 CAR23806.1 - 3.8e-21 74.6 0.0 6.6e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 CAR23806.1 - 0.023 15.2 0.0 0.058 13.9 0.0 1.6 1 0 0 1 1 1 0 HIT domain Fumble PF03630.9 CAR23807.1 - 3.8e-127 423.8 1.0 2.2e-124 414.7 0.1 2.0 1 1 1 2 2 2 2 Fumble Synaptobrevin PF00957.16 CAR23808.1 - 0.12 12.0 3.8 0.079 12.5 0.6 2.3 2 0 0 2 2 2 0 Synaptobrevin UPF0449 PF15136.1 CAR23808.1 - 0.87 9.8 7.9 5.9 7.1 0.1 3.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Reo_sigmaC PF04582.7 CAR23808.1 - 2.6 7.1 6.5 1 8.4 1.6 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Tra_M PF05261.6 CAR23808.1 - 4 7.5 8.0 22 5.1 0.1 4.1 3 2 1 4 4 4 0 TraM protein, DNA-binding FUSC PF04632.7 CAR23808.1 - 4.2 5.6 6.2 6 5.1 4.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RPAP1_C PF08620.5 CAR23809.1 - 3.9e-31 106.7 0.0 7.1e-31 105.8 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CAR23809.1 - 3.4e-15 55.3 3.8 7.2e-15 54.3 2.6 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 CAR23809.1 - 0.062 13.4 0.1 0.69 10.1 0.0 2.7 3 0 0 3 3 3 0 HEAT repeat Pmp3 PF01679.12 CAR23810.1 - 8.5e-21 73.4 2.3 9.8e-21 73.2 1.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Asp_Glu_race PF01177.17 CAR23811.1 - 2e-16 60.5 1.0 2.5e-16 60.2 0.7 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase ArfGap PF01412.13 CAR23812.1 - 3.3e-33 113.9 1.7 9.1e-33 112.5 1.2 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 CAR23812.1 - 1.5e-10 41.1 0.7 3.6e-10 39.9 0.1 2.0 2 0 0 2 2 2 1 PH domain LRR19-TM PF15176.1 CAR23812.1 - 0.098 12.3 0.1 0.34 10.6 0.1 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Pkinase PF00069.20 CAR23813.1 - 3.7e-67 226.2 0.0 5.2e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23813.1 - 1.5e-46 158.5 0.0 2.3e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23813.1 - 1e-06 27.9 0.0 9.5e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like CENP-R PF06729.7 CAR23813.1 - 0.049 13.3 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 Kinetochore component, CENP-R ABC1 PF03109.11 CAR23813.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Recep_L_domain PF01030.19 CAR23814.1 - 5.2e-07 29.6 0.6 0.0018 18.2 0.0 4.2 1 1 1 4 4 4 3 Receptor L domain LRR_4 PF12799.2 CAR23814.1 - 0.24 11.0 8.7 0.1 12.2 0.7 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Zn_clus PF00172.13 CAR23815.1 - 0.0012 18.7 7.0 0.0024 17.7 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTP_transf_2 PF01467.21 CAR23816.1 - 5.1e-09 36.3 0.0 8.6e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase FKBP_C PF00254.23 CAR23817.1 - 4e-30 103.6 0.0 4.9e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1620 PF07774.8 CAR23818.1 - 8e-70 234.4 0.3 6.4e-69 231.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CAR23818.1 - 2.1e-05 24.0 0.0 0.0036 16.7 0.0 2.8 2 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 CAR23818.1 - 0.015 14.7 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat COX5A PF02284.11 CAR23818.1 - 0.1 12.5 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Mgr1 PF08602.5 CAR23819.1 - 3.7e-125 417.7 0.0 4.4e-125 417.4 0.0 1.1 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.15 CAR23820.1 - 7.4e-57 189.4 0.0 5.4e-29 99.9 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CAR23820.1 - 2.7e-32 112.0 1.5 9.2e-23 80.9 1.4 4.3 4 1 1 5 5 5 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CAR23820.1 - 2.1e-11 43.6 0.4 0.00057 19.8 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CAR23820.1 - 8e-09 35.6 3.5 0.012 15.7 0.1 4.5 3 3 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAR23820.1 - 2.2e-07 30.8 0.0 0.04 14.0 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CAR23820.1 - 9e-06 25.3 0.2 0.0068 16.0 0.0 3.3 2 1 1 3 3 3 1 AhpC/TSA family Calsequestrin PF01216.12 CAR23820.1 - 5.5e-05 22.1 0.0 9.7e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.5 CAR23820.1 - 0.00024 20.6 0.3 0.35 10.4 0.0 2.6 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 CAR23820.1 - 0.047 13.6 2.9 1.3 9.0 0.2 3.5 2 2 0 3 3 3 0 Thioredoxin Thioredoxin_9 PF14595.1 CAR23820.1 - 0.088 12.3 0.1 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 CAR23820.1 - 0.092 12.5 0.5 2 8.2 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin domain GRASP55_65 PF04495.9 CAR23821.1 - 4.9e-34 117.2 0.0 1.4e-31 109.3 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Hexokinase_2 PF03727.11 CAR23822.1 - 1.9e-85 285.9 0.0 2.6e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CAR23822.1 - 1.2e-70 237.0 0.0 1.8e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.27 CAR23823.1 - 1.4e-20 72.3 7.1 2.3e-05 24.0 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat LisH PF08513.6 CAR23823.1 - 0.027 14.2 0.2 0.081 12.7 0.1 1.9 1 0 0 1 1 1 0 LisH Lactonase PF10282.4 CAR23823.1 - 0.046 12.7 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ATG22 PF11700.3 CAR23824.1 - 1.7e-157 524.7 24.4 2e-157 524.5 16.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like La PF05383.12 CAR23825.1 - 8.1e-20 70.3 0.0 2.4e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 La domain DUF573 PF04504.9 CAR23826.1 - 0.78 10.0 3.4 5.8 7.2 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Flocculin_t3 PF13928.1 CAR23827.1 - 2e-09 37.4 139.8 9.9e-05 22.4 17.6 9.7 6 3 2 8 8 8 5 Flocculin type 3 repeat Glutaredoxin PF00462.19 CAR23828.1 - 2.4e-13 49.8 0.0 3.8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 CAR23828.1 - 0.00076 19.0 0.0 0.00097 18.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CAR23828.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like GAT PF03127.9 CAR23829.1 - 5.4e-07 29.5 0.2 1.2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 CAR23829.1 - 0.0047 16.5 0.1 0.0091 15.6 0.1 1.7 1 1 0 1 1 1 1 VHS domain DsrC PF04358.8 CAR23829.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 DsrC like protein Herpes_BBRF1 PF04793.7 CAR23829.1 - 0.16 10.6 0.1 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 BRRF1-like protein SelR PF01641.13 CAR23830.1 - 4.1e-51 171.8 0.6 5e-51 171.5 0.4 1.1 1 0 0 1 1 1 1 SelR domain GFA PF04828.9 CAR23830.1 - 0.021 14.7 2.4 2.4 8.1 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 CAR23830.1 - 0.021 14.6 3.7 0.083 12.7 2.3 2.0 1 1 1 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.9 CAR23830.1 - 0.037 14.0 1.9 0.097 12.7 1.3 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RRN7 PF11781.3 CAR23830.1 - 0.041 13.3 2.0 6.6 6.3 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 HECT_2 PF09814.4 CAR23830.1 - 0.082 11.6 0.3 1.6 7.3 0.1 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-IS66 PF13005.2 CAR23830.1 - 0.44 10.5 3.1 0.71 9.8 0.3 2.2 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-Mss51 PF13824.1 CAR23830.1 - 3 7.7 7.1 2.8 7.8 0.1 2.9 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3128 PF11326.3 CAR23831.1 - 2.7e-31 107.5 1.4 3e-31 107.3 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) IBV_3B PF03622.8 CAR23831.1 - 0.3 11.0 1.3 0.65 10.0 0.5 1.9 1 1 1 2 2 2 0 IBV 3B protein RA PF00788.18 CAR23832.1 - 5.2e-16 58.9 0.2 2.4e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ste50p-SAM PF09235.5 CAR23832.1 - 1.7e-14 53.5 1.3 3.3e-14 52.6 0.9 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RRP7 PF12923.2 CAR23833.1 - 4.5e-34 117.2 10.3 4.5e-34 117.2 7.1 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Adenyl_cycl_N PF12633.2 CAR23833.1 - 0.02 14.4 0.7 0.065 12.7 0.2 2.0 1 1 1 2 2 2 0 Adenylate cyclase NT domain Complex1_LYR PF05347.10 CAR23834.1 - 2.7e-10 39.8 0.0 5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAR23834.1 - 3.5e-09 36.7 0.0 5.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CAR23834.1 - 2.4e-06 27.9 0.0 3.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 CAR23834.1 - 0.02 14.5 0.2 0.074 12.6 0.0 2.0 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Histidinol_dh PF00815.15 CAR23835.1 - 3.8e-186 618.6 2.1 6.3e-186 617.9 1.5 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 CAR23835.1 - 2.4e-27 94.3 0.2 5.4e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CAR23835.1 - 3.3e-14 52.9 0.3 3.3e-14 52.9 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 CAR23835.1 - 0.66 9.9 4.2 0.21 11.5 0.3 2.1 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain CAP_GLY PF01302.20 CAR23836.1 - 7.6e-16 57.5 1.2 1.3e-15 56.8 0.4 1.6 2 0 0 2 2 2 1 CAP-Gly domain PspA_IM30 PF04012.7 CAR23836.1 - 0.01 15.1 39.2 0.01 15.2 17.7 2.7 1 1 2 3 3 3 0 PspA/IM30 family DUF1136 PF06582.7 CAR23836.1 - 0.03 13.9 0.1 0.03 13.9 0.1 3.8 4 0 0 4 4 4 0 Repeat of unknown function (DUF1136) CorA PF01544.13 CAR23836.1 - 0.089 11.8 18.7 0.8 8.6 6.3 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein AAA_13 PF13166.1 CAR23836.1 - 0.093 11.1 30.2 0.028 12.9 18.2 1.7 1 1 1 2 2 2 0 AAA domain Lebercilin PF15619.1 CAR23836.1 - 0.11 11.9 40.5 0.083 12.3 11.3 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mnd1 PF03962.10 CAR23836.1 - 0.12 12.0 35.1 1.7 8.2 6.9 2.8 1 1 2 3 3 3 0 Mnd1 family Filament PF00038.16 CAR23836.1 - 0.14 11.5 34.8 0.17 11.2 8.7 2.7 2 1 0 2 2 2 0 Intermediate filament protein DUF4200 PF13863.1 CAR23836.1 - 0.37 10.7 41.8 1.7 8.5 11.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 CAR23836.1 - 0.43 9.1 36.6 0.29 9.7 8.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CAR23836.1 - 0.45 9.6 10.6 2.5 7.1 3.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 CAR23836.1 - 1 8.9 50.9 5.2 6.6 16.5 2.3 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 CAR23836.1 - 1.3 6.2 33.7 2.4 5.3 23.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3896 PF13035.1 CAR23836.1 - 1.9 8.5 16.6 0.86 9.7 0.5 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3896) Uds1 PF15456.1 CAR23836.1 - 3.1 7.8 32.0 0.66 9.9 5.9 3.1 1 1 2 3 3 3 0 Up-regulated During Septation Tropomyosin_1 PF12718.2 CAR23836.1 - 3.7 7.3 45.8 3.9 7.3 13.5 2.7 1 1 1 2 2 2 0 Tropomyosin like Phage_Nu1 PF07471.7 CAR23836.1 - 3.8 6.9 15.6 2.6 7.5 0.8 3.5 2 2 0 3 3 3 0 Phage DNA packaging protein Nu1 SPX PF03105.14 CAR23836.1 - 6 6.5 18.2 9.9 5.8 12.6 1.4 1 0 0 1 1 1 0 SPX domain TMPIT PF07851.8 CAR23836.1 - 7.2 5.5 26.9 0.28 10.1 5.9 2.4 1 1 1 2 2 2 0 TMPIT-like protein DUF1664 PF07889.7 CAR23836.1 - 7.3 6.4 17.7 0.24 11.2 2.2 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.4 CAR23836.1 - 7.5 6.5 28.2 1.8 8.4 9.0 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Myb_DNA-bind_4 PF13837.1 CAR23836.1 - 8.9 6.5 11.0 1.3 9.1 1.8 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Laminin_II PF06009.7 CAR23836.1 - 9.4 5.9 24.0 3.3 7.4 4.7 2.9 1 1 2 3 3 3 0 Laminin Domain II FlxA PF14282.1 CAR23836.1 - 9.6 6.2 41.7 2.5 8.0 6.8 3.3 2 1 1 3 3 3 0 FlxA-like protein TPR_11 PF13414.1 CAR23838.1 - 0.00069 19.2 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CAR23838.1 - 0.0018 18.0 0.0 0.0069 16.2 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR23838.1 - 0.0025 17.3 0.0 0.011 15.3 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 CAR23838.1 - 0.029 14.4 0.3 0.053 13.6 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAR23838.1 - 0.055 14.1 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_pol_Rpb1_6 PF04992.9 CAR23838.1 - 0.075 12.7 0.2 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 TPR_19 PF14559.1 CAR23838.1 - 0.19 12.0 0.5 0.38 11.1 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAR23838.1 - 0.19 12.4 0.0 0.42 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP PF00188.21 CAR23839.1 - 5.2e-20 72.1 2.8 1.9e-19 70.3 1.9 2.0 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SH3_9 PF14604.1 CAR23840.1 - 0.00062 19.2 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.1 CAR23840.1 - 0.0037 16.7 0.0 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SH3_1 PF00018.23 CAR23840.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 CAR23840.1 - 0.0057 15.9 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SH3_2 PF07653.12 CAR23840.1 - 0.0085 15.5 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Nitroreductase PF00881.19 CAR23841.1 - 8.8e-07 28.8 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family AA_permease PF00324.16 CAR23842.1 - 2.7e-130 434.9 33.1 3.3e-130 434.6 22.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23842.1 - 2e-33 115.5 35.3 2.5e-33 115.2 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease OapA_N PF08525.6 CAR23842.1 - 0.067 12.9 0.4 0.32 10.8 0.3 2.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif DUF2416 PF10315.4 CAR23842.1 - 0.18 12.0 2.5 0.12 12.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2416) AA_permease PF00324.16 CAR23843.1 - 9e-127 423.2 35.0 1.1e-126 422.9 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23843.1 - 1.4e-33 116.0 35.9 1.7e-33 115.7 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease Rad60-SLD PF11976.3 CAR23845.1 - 3.7e-21 74.5 0.1 4.9e-21 74.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CAR23845.1 - 1.4e-12 46.8 0.0 1.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 CAR23846.1 - 1.9e-73 246.8 0.0 3.8e-73 245.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23846.1 - 5.5e-35 120.6 0.0 1.3e-34 119.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23846.1 - 3.9e-07 29.3 0.0 1e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAR23846.1 - 0.2 11.3 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cu-oxidase_2 PF07731.9 CAR23847.1 - 3e-35 120.7 2.6 6.2e-32 109.9 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CAR23847.1 - 3.3e-22 78.4 9.1 5.4e-19 68.0 2.1 5.0 4 2 1 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.17 CAR23847.1 - 2.2e-20 73.1 0.1 1.8e-18 66.9 0.0 3.0 3 1 0 3 3 3 1 Multicopper oxidase DUF1180 PF06679.7 CAR23847.1 - 1.1 9.0 5.4 1.9 8.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PSP1 PF04468.7 CAR23848.1 - 1.6e-35 120.9 1.0 1.6e-35 120.9 0.7 2.1 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Sporozoite_P67 PF05642.6 CAR23848.1 - 0.00032 18.7 4.1 0.00055 17.9 2.9 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Med15 PF09606.5 CAR23848.1 - 0.038 12.2 25.2 0.058 11.5 17.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Phostensin_N PF13916.1 CAR23848.1 - 0.26 11.2 4.0 1.6 8.7 2.5 2.5 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal PBP PF01161.15 CAR23849.1 - 5.4e-34 117.1 0.1 7e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PAP2 PF01569.16 CAR23850.1 - 4.8e-20 71.5 1.6 4.8e-20 71.5 1.1 2.0 1 1 2 3 3 3 1 PAP2 superfamily PAP2_C PF14360.1 CAR23850.1 - 0.017 15.3 4.3 0.018 15.3 1.9 1.8 2 0 0 2 2 2 0 PAP2 superfamily C-terminal FUSC_2 PF13515.1 CAR23850.1 - 0.034 14.0 1.6 0.034 14.0 1.1 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein-like S-AdoMet_synt_C PF02773.11 CAR23851.1 - 2.1e-74 247.8 0.1 3.3e-74 247.1 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CAR23851.1 - 4.6e-48 162.1 0.0 1.1e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CAR23851.1 - 1.4e-44 150.4 0.1 2.7e-44 149.4 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DUF605 PF04652.11 CAR23852.1 - 7.3e-52 177.0 6.6 1.1e-51 176.4 4.6 1.3 1 0 0 1 1 1 1 Vta1 like B PF02216.11 CAR23852.1 - 0.018 14.7 0.2 0.059 13.1 0.1 1.9 1 0 0 1 1 1 0 B domain Ank_2 PF12796.2 CAR23853.1 - 1e-13 51.3 0.2 4.6e-05 23.6 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CAR23853.1 - 7.4e-13 48.2 1.8 1.2e-07 31.7 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CAR23853.1 - 8.2e-11 41.1 4.0 1e-06 28.2 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CAR23853.1 - 1.8e-10 40.0 1.2 5.8e-05 22.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CAR23853.1 - 2e-09 37.6 2.3 0.00029 21.2 0.0 4.7 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Cor1 PF04803.7 CAR23853.1 - 0.056 13.1 5.4 0.16 11.7 3.7 1.7 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Phlebovirus_NSM PF07246.6 CAR23853.1 - 0.096 11.8 3.5 0.16 11.0 2.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GAS PF13851.1 CAR23853.1 - 0.16 11.1 12.6 0.38 9.9 6.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CHD5 PF04420.9 CAR23853.1 - 0.27 10.8 3.8 0.7 9.5 2.6 1.6 1 0 0 1 1 1 0 CHD5-like protein Baculo_PEP_C PF04513.7 CAR23853.1 - 0.69 9.7 5.7 0.47 10.2 1.7 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.9 CAR23853.1 - 2.3 8.1 10.9 0.29 11.0 4.6 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 CAR23853.1 - 3 6.1 7.7 0.28 9.5 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 CAR23853.1 - 4.3 6.9 10.6 3.1 7.4 3.0 2.5 2 0 0 2 2 2 0 Mnd1 family DUF4559 PF15112.1 CAR23853.1 - 4.8 6.2 8.8 0.41 9.7 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) FHA PF00498.21 CAR23854.1 - 3.8e-06 26.9 0.0 1.2e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 FHA domain Erp_C PF06780.6 CAR23854.1 - 0.051 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Erp protein C-terminus Aldo_ket_red PF00248.16 CAR23855.1 - 1.4e-36 125.8 0.0 1.7e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L37e PF01907.14 CAR23856.1 - 1.6e-28 98.2 11.7 2.6e-28 97.5 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 CAR23856.1 - 0.00067 19.4 1.7 0.00099 18.8 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.17 CAR23856.1 - 0.022 14.4 2.8 0.034 13.8 1.9 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_6 PF14599.1 CAR23856.1 - 0.04 13.7 2.3 0.06 13.1 1.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon DUF1258 PF06869.7 CAR23856.1 - 0.057 12.5 0.3 0.06 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) SelR PF01641.13 CAR23856.1 - 0.058 13.0 0.3 0.078 12.6 0.2 1.3 1 1 0 1 1 1 0 SelR domain zf-C3HC4_3 PF13920.1 CAR23856.1 - 0.19 11.4 2.8 0.26 10.9 2.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR23856.1 - 0.25 11.1 3.7 0.37 10.5 2.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain GATA PF00320.22 CAR23856.1 - 0.26 10.6 6.1 0.26 10.6 0.7 2.3 1 1 1 2 2 2 0 GATA zinc finger zf-ribbon_3 PF13248.1 CAR23856.1 - 0.48 9.7 5.0 2.1 7.6 3.4 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CAR23856.1 - 1.3 8.6 4.8 9.9 5.7 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 CAR23856.1 - 1.3 9.0 5.2 2 8.5 3.6 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.1 CAR23856.1 - 5.6 6.8 6.4 4.4 7.1 0.7 2.2 1 1 1 2 2 2 0 YhfH-like protein zf-HYPF PF07503.7 CAR23856.1 - 7 6.1 8.5 17 4.9 3.6 2.6 2 1 1 3 3 3 0 HypF finger LCD1 PF09798.4 CAR23857.1 - 2.6e-159 531.2 1.9 3e-159 531.0 1.3 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein EMG1 PF03587.9 CAR23858.1 - 3.4e-77 258.3 0.0 4.1e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase YbaJ PF10757.4 CAR23859.1 - 0.005 16.9 0.1 0.014 15.4 0.1 1.8 1 0 0 1 1 1 1 Biofilm formation regulator YbaJ Peptidase_M56 PF05569.6 CAR23859.1 - 0.37 9.7 12.7 0.06 12.3 2.9 2.9 3 0 0 3 3 3 0 BlaR1 peptidase M56 PH PF00169.24 CAR23860.1 - 5.8e-07 29.6 0.1 1.6e-05 25.0 0.0 2.7 2 0 0 2 2 2 1 PH domain ABC_membrane PF00664.18 CAR23861.1 - 5.8e-56 189.9 3.6 7.7e-56 189.5 2.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CAR23861.1 - 1.8e-30 105.9 0.1 1.5e-29 103.0 0.0 2.6 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 CAR23861.1 - 2.3e-06 26.9 0.0 1.1e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CAR23861.1 - 7.2e-06 26.1 0.1 0.01 15.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CAR23861.1 - 0.00011 22.2 0.9 0.66 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CAR23861.1 - 0.00044 21.0 0.0 0.0013 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR23861.1 - 0.00071 19.6 0.1 0.0028 17.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CAR23861.1 - 0.0039 16.9 0.2 0.1 12.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CAR23861.1 - 0.007 15.7 0.0 0.052 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAR23861.1 - 0.0081 15.6 0.0 0.025 14.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CAR23861.1 - 0.0094 16.2 0.1 0.14 12.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR23861.1 - 0.012 15.0 0.0 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.1 CAR23861.1 - 0.028 14.3 0.5 0.18 11.7 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 CAR23861.1 - 0.039 12.5 0.0 0.095 11.2 0.0 1.6 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF87 PF01935.12 CAR23861.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA PF00004.24 CAR23861.1 - 0.044 13.9 0.3 2.7 8.1 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 CAR23861.1 - 0.047 13.1 0.0 0.24 10.8 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase LpxD PF04613.9 CAR23861.1 - 0.059 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD DUF258 PF03193.11 CAR23861.1 - 0.06 12.5 0.0 0.19 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CAR23861.1 - 0.073 13.2 0.2 3.2 7.9 0.0 2.9 2 1 1 3 3 3 0 RNA helicase AAA_33 PF13671.1 CAR23861.1 - 0.11 12.3 1.5 2.5 7.9 0.0 3.3 4 0 0 4 4 3 0 AAA domain Abhydrolase_1 PF00561.15 CAR23862.1 - 1.1e-61 208.3 0.0 1.5e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR23862.1 - 3.7e-12 46.6 0.1 3.4e-11 43.4 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR23862.1 - 0.00072 19.3 0.0 0.014 15.1 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_28 PF03033.15 CAR23863.1 - 4.9e-26 91.1 0.0 1.1e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CAR23863.1 - 3.4e-18 64.9 3.6 4.6e-16 58.0 0.1 3.4 4 0 0 4 4 4 2 GRAM domain PH PF00169.24 CAR23863.1 - 2.8e-12 46.7 1.2 6.8e-12 45.5 0.0 2.3 3 0 0 3 3 3 1 PH domain UDPGT PF00201.13 CAR23863.1 - 6.5e-09 34.8 0.0 1.5e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.1 CAR23863.1 - 0.00015 22.0 0.2 0.0064 16.7 0.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Glyco_trans_4_4 PF13579.1 CAR23863.1 - 0.035 14.2 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_3 PF13528.1 CAR23863.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Exo_endo_phos PF03372.18 CAR23864.1 - 4.5e-17 62.8 0.1 8e-17 61.9 0.0 1.4 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family HXXEE PF13787.1 CAR23864.1 - 0.011 16.0 2.3 0.02 15.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif Spindle_Spc25 PF08234.7 CAR23865.1 - 2.3e-16 59.5 0.0 6.1e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 M PF02370.11 CAR23865.1 - 0.15 12.4 12.2 1.3 9.6 0.0 3.8 3 0 0 3 3 3 0 M protein repeat Spc24 PF08286.6 CAR23865.1 - 0.28 10.8 19.0 0.078 12.6 6.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 CAR23865.1 - 0.37 9.7 23.7 0.52 9.2 16.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_S46 PF10459.4 CAR23865.1 - 4.3 5.6 9.1 4.7 5.5 6.3 1.1 1 0 0 1 1 1 0 Peptidase S46 CENP-F_leu_zip PF10473.4 CAR23865.1 - 5.2 6.9 26.8 4.2 7.2 12.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 CAR23865.1 - 7.9 5.3 28.6 49 2.7 19.6 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Per1 PF04080.8 CAR23866.1 - 1.9e-95 319.3 8.8 2.3e-95 319.0 6.1 1.1 1 0 0 1 1 1 1 Per1-like Ceramidase PF05875.7 CAR23866.1 - 0.00062 18.9 5.6 0.0033 16.5 1.9 2.2 1 1 1 2 2 2 1 Ceramidase DUF3611 PF12263.3 CAR23866.1 - 0.023 14.1 0.4 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Ni_hydr_CYTB PF01292.15 CAR23866.1 - 0.3 10.4 8.1 0.022 14.1 1.5 2.0 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 HCO3_cotransp PF00955.16 CAR23867.1 - 9.6e-55 186.1 10.5 4.6e-34 117.9 1.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF4235 PF14019.1 CAR23867.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DUF4190 PF13828.1 CAR23868.1 - 0.11 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) 2-Hacid_dh_C PF02826.14 CAR23869.1 - 1.3e-56 190.5 0.0 3e-56 189.3 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CAR23869.1 - 3.6e-13 49.1 0.0 5.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CAR23869.1 - 2.5e-06 27.4 0.3 1.8e-05 24.6 0.0 2.3 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CAR23869.1 - 0.00014 21.2 0.0 0.0004 19.7 0.0 1.8 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 CAR23869.1 - 0.0032 17.5 0.0 0.0093 16.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 CAR23869.1 - 0.045 13.5 0.9 0.65 9.8 0.1 2.7 1 1 1 2 2 2 0 ThiF family AgrD PF05931.6 CAR23869.1 - 0.19 11.4 0.5 0.35 10.5 0.4 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein Peptidase_M1 PF01433.15 CAR23870.1 - 3.6e-10 39.4 0.1 0.00013 21.2 0.0 3.2 2 1 1 3 3 3 2 Peptidase family M1 Sad1_UNC PF07738.8 CAR23871.1 - 2.3e-32 111.5 0.1 2.3e-32 111.5 0.0 2.4 3 0 0 3 3 3 1 Sad1 / UNC-like C-terminal Cyclin_N PF00134.18 CAR23872.1 - 1.8e-37 127.6 0.8 1.5e-36 124.7 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR23872.1 - 0.007 16.2 1.4 0.007 16.2 1.0 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain Peptidase_S8 PF00082.17 CAR23873.1 - 1e-22 80.6 1.2 1.4e-22 80.1 0.9 1.2 1 0 0 1 1 1 1 Subtilase family TIMELESS PF04821.9 CAR23874.1 - 1.1e-53 182.1 0.2 3.3e-53 180.6 0.1 1.9 1 0 0 1 1 1 1 Timeless protein Aa_trans PF01490.13 CAR23875.1 - 3.2e-82 276.1 27.6 3.7e-82 275.9 19.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sec2p PF06428.6 CAR23876.1 - 1.9e-27 95.0 13.2 1.9e-27 95.0 9.2 2.6 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Histone PF00125.19 CAR23876.1 - 0.056 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 T2SM_b PF10741.4 CAR23876.1 - 0.47 10.0 6.5 0.14 11.7 1.0 2.6 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M subtype b DUF464 PF04327.7 CAR23876.1 - 3 8.1 7.0 2.8 8.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF464) IncA PF04156.9 CAR23876.1 - 3.3 7.2 37.0 2.9 7.4 6.5 2.9 1 1 1 2 2 2 0 IncA protein FH2 PF02181.18 CAR23877.1 - 3.4e-84 282.8 8.4 3.4e-84 282.8 5.8 3.0 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CAR23877.1 - 7.7e-48 162.5 0.2 7.7e-48 162.5 0.1 4.1 4 0 0 4 4 4 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 CAR23877.1 - 1.9e-32 112.1 0.8 1.9e-32 112.1 0.5 3.5 3 2 1 4 4 4 1 Diaphanous GTPase-binding Domain AA_permease PF00324.16 CAR23878.1 - 8.5e-139 462.9 43.5 1e-138 462.6 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23878.1 - 2.1e-32 112.2 50.8 3.3e-32 111.5 35.1 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR23879.1 - 1.3e-128 429.4 45.4 1.5e-128 429.1 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23879.1 - 3.4e-32 111.5 49.1 4.3e-32 111.1 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 CAR23879.1 - 0.94 8.9 6.2 1.1 8.6 0.4 3.1 3 0 0 3 3 3 0 Intrinsic membrane protein PufX PI3_PI4_kinase PF00454.22 CAR23880.1 - 6.1e-31 107.7 0.0 1.3e-30 106.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 CAR23880.1 - 3.3e-20 71.5 0.6 1.1e-19 69.8 0.4 2.0 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 CAR23880.1 - 1.1e-06 27.9 2.1 2.4e-06 26.8 1.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Mmp37 PF09139.6 CAR23881.1 - 4.8e-104 347.9 6.7 6.1e-95 318.0 1.5 2.1 1 1 1 2 2 2 2 Mitochondrial matrix Mmp37 Ist1 PF03398.9 CAR23882.1 - 1.2e-51 174.4 2.8 1.9e-51 173.7 1.9 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TPR_16 PF13432.1 CAR23883.1 - 9e-17 61.2 5.8 0.0077 16.8 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CAR23883.1 - 1.2e-15 57.2 16.7 0.00054 19.8 0.0 7.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAR23883.1 - 6.3e-15 54.5 17.2 3.7e-07 29.6 0.0 7.4 6 1 1 8 8 8 4 TPR repeat TPR_19 PF14559.1 CAR23883.1 - 1.7e-11 44.2 5.9 0.0078 16.5 0.2 6.9 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR23883.1 - 1.8e-11 43.0 21.7 1.1 9.3 0.0 10.5 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 CAR23883.1 - 2.5e-08 33.4 6.0 0.36 11.1 0.0 6.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR23883.1 - 6.3e-08 32.5 1.4 1.8 9.3 0.0 7.7 5 1 4 9 9 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR23883.1 - 5.2e-07 29.0 23.4 0.24 11.0 0.0 8.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 CAR23883.1 - 1.3e-06 28.1 0.5 0.63 9.9 0.1 4.8 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 CAR23883.1 - 6.5e-06 26.2 8.8 0.33 11.5 0.0 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 CAR23883.1 - 5.1e-05 23.3 3.4 0.54 10.4 0.1 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR23883.1 - 9.6e-05 21.9 6.9 28 4.8 0.0 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR23883.1 - 0.0021 17.7 20.7 0.042 13.6 0.1 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CAR23883.1 - 0.015 15.5 0.2 0.53 10.5 0.0 2.9 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation UFD1 PF03152.9 CAR23884.1 - 2.4e-73 245.0 0.0 3e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF2422 PF10337.4 CAR23885.1 - 3.2e-50 171.2 1.3 3.2e-50 171.2 0.9 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CAR23885.1 - 2.5e-12 46.8 13.2 2.5e-12 46.8 9.2 2.7 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 CAR23885.1 - 1.4e-09 37.1 4.2 2.1e-07 29.9 0.7 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 CAR23885.1 - 1.4e-06 28.0 2.2 5.8e-06 26.0 1.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) DUF2680 PF10925.3 CAR23885.1 - 0.13 12.1 0.7 0.35 10.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) FUSC PF04632.7 CAR23885.1 - 1.8 6.8 7.0 4.3 5.6 4.6 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family CRAL_TRIO PF00650.15 CAR23886.1 - 2.1e-34 118.3 0.0 3e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR23886.1 - 4.1e-06 26.8 1.3 8.9e-06 25.7 0.4 2.1 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CAR23886.1 - 4.8e-05 23.3 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FDC-SP PF15215.1 CAR23886.1 - 1.1 9.6 3.2 11 6.4 0.4 2.3 1 1 1 2 2 2 0 Follicular dendritic cell secreted peptide DnaJ PF00226.26 CAR23887.1 - 4.8e-14 51.8 0.2 9.9e-14 50.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain YIF1 PF03878.10 CAR23888.1 - 2.8e-69 232.9 7.6 4e-69 232.4 5.3 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CAR23888.1 - 0.0019 17.6 7.0 0.0038 16.7 4.8 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1744 PF08490.7 CAR23889.1 - 1.5e-141 471.6 2.8 2.7e-141 470.7 2.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CAR23889.1 - 2.9e-68 230.1 1.7 7.5e-68 228.7 1.2 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CAR23889.1 - 3.1e-24 85.6 1.7 6.6e-24 84.5 1.2 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CAR23889.1 - 3e-07 30.1 0.3 2.4e-06 27.2 0.2 2.6 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ORC5_C PF14630.1 CAR23890.1 - 9.5e-67 225.2 0.8 1.5e-66 224.6 0.6 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 CAR23890.1 - 3.6e-06 27.0 0.0 7.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain CRAL_TRIO_2 PF13716.1 CAR23890.1 - 0.00045 20.1 1.6 0.0012 18.7 0.3 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain AAA_22 PF13401.1 CAR23890.1 - 0.0083 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CAR23890.1 - 0.012 15.2 1.3 0.09 12.4 0.9 2.2 1 1 0 1 1 1 0 NACHT domain GYF PF02213.11 CAR23891.1 - 2.7e-09 36.4 0.8 5.5e-09 35.4 0.6 1.6 1 0 0 1 1 1 1 GYF domain Yae1_N PF09811.4 CAR23892.1 - 1.8e-09 36.9 4.5 1.1e-08 34.4 3.1 2.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal HMA PF00403.21 CAR23893.1 - 4.9e-13 49.0 0.2 5.8e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain zf-C4 PF00105.13 CAR23893.1 - 0.055 13.7 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) E7 PF00527.13 CAR23893.1 - 0.14 12.3 0.3 0.31 11.2 0.1 1.6 1 1 1 2 2 2 0 E7 protein, Early protein Dsl1_N PF11988.3 CAR23894.1 - 3.6e-137 456.9 13.0 6.2e-137 456.2 7.8 1.9 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.3 CAR23894.1 - 5.5e-101 337.5 1.5 5.5e-101 337.5 1.1 1.9 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal CENP-B_N PF04218.8 CAR23894.1 - 0.017 14.5 0.2 0.89 9.0 0.0 3.1 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain PH PF00169.24 CAR23895.1 - 1.4e-05 25.2 0.0 4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 PH domain KH_4 PF13083.1 CAR23895.1 - 0.063 12.9 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 KH domain PGAP1 PF07819.8 CAR23896.1 - 1.1e-07 31.6 0.0 4.5e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 CAR23896.1 - 3.7e-05 23.1 0.0 8.7e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CAR23896.1 - 0.0024 17.8 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 CAR23896.1 - 0.0036 16.3 0.0 0.0057 15.6 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 CAR23896.1 - 0.0037 16.8 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR23896.1 - 0.027 14.2 0.0 0.099 12.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF915 PF06028.6 CAR23896.1 - 0.044 12.8 0.0 0.37 9.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RRM_1 PF00076.17 CAR23897.1 - 6.8e-16 57.6 0.0 1.5e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 CAR23897.1 - 1.6e-14 54.3 0.0 2.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_6 PF14259.1 CAR23897.1 - 1.7e-09 37.5 0.0 3.6e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR23897.1 - 3.7e-09 36.2 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.14 CAR23898.1 - 7.9e-22 77.7 0.3 4.2e-10 39.2 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 CAR23898.1 - 3.9e-06 26.0 0.0 0.0019 17.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CAR23898.1 - 0.00057 18.9 0.2 0.011 14.7 0.1 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.9 CAR23898.1 - 0.0031 16.2 0.0 0.25 9.9 0.0 2.8 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 CAR23898.1 - 0.006 16.5 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 CAR23898.1 - 0.01 14.7 0.1 0.03 13.1 0.0 1.8 3 0 0 3 3 3 0 Squalene epoxidase Pyr_redox_2 PF07992.9 CAR23898.1 - 0.013 15.4 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAR23898.1 - 0.019 14.0 0.0 0.08 12.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 CAR23898.1 - 0.023 13.5 0.7 0.034 12.9 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CAR23898.1 - 0.038 12.4 0.2 0.079 11.4 0.1 1.6 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 CAR23898.1 - 0.13 12.2 0.0 0.73 9.8 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pterin_bind PF00809.17 CAR23899.1 - 2.9e-45 154.2 0.5 1.8e-42 145.1 0.1 3.2 2 1 0 2 2 2 1 Pterin binding enzyme FolB PF02152.13 CAR23899.1 - 2.5e-41 140.3 0.1 6.8e-20 71.3 0.0 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.15 CAR23899.1 - 1.6e-39 134.5 0.0 3.4e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) zf-CCHC PF00098.18 CAR23900.1 - 1.1e-52 173.5 50.1 2.7e-08 33.3 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CAR23900.1 - 5e-11 42.0 42.1 0.0059 16.2 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 CAR23900.1 - 2.2e-06 27.0 45.5 0.15 11.6 0.5 7.1 3 3 4 7 7 7 5 Zinc knuckle zf-CCHC_3 PF13917.1 CAR23900.1 - 0.0032 17.1 42.1 1.6 8.5 0.2 7.0 1 1 4 5 5 5 5 Zinc knuckle RTC4 PF14474.1 CAR23901.1 - 6.2e-38 129.5 0.0 1.1e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain WD40 PF00400.27 CAR23902.1 - 8.4e-16 57.1 2.2 9.4e-07 28.4 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 CAR23902.1 - 0.033 12.8 0.0 0.068 11.8 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) SdiA-regulated PF06977.6 CAR23902.1 - 0.092 11.6 0.1 0.53 9.2 0.0 2.1 3 0 0 3 3 3 0 SdiA-regulated MRP-L46 PF11788.3 CAR23903.1 - 2.2e-39 134.5 0.2 3.5e-39 133.8 0.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 RRM_6 PF14259.1 CAR23904.1 - 1.6e-08 34.3 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR23904.1 - 1.8e-07 30.6 0.0 3.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR23904.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 CAR23904.1 - 0.04 14.1 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 RNA polymerase II-binding domain. OS-D PF03392.8 CAR23904.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D CTK3 PF12243.3 CAR23904.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Zn_clus PF00172.13 CAR23905.1 - 5.9e-06 26.0 11.6 1.2e-05 25.0 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CAR23906.1 - 1.4e-13 50.3 40.3 1.6e-12 46.8 15.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily AAA_23 PF13476.1 CAR23907.1 - 3.8e-15 56.7 48.2 3.8e-15 56.7 33.4 8.2 2 1 2 4 4 4 1 AAA domain Rad50_zn_hook PF04423.9 CAR23907.1 - 1.6e-14 53.0 4.2 1.6e-14 53.0 2.9 4.7 4 0 0 4 4 4 1 Rad50 zinc hook motif AAA_13 PF13166.1 CAR23907.1 - 1.8e-11 43.2 124.9 2.7e-05 22.8 0.0 7.0 2 1 5 8 8 8 5 AAA domain SbcCD_C PF13558.1 CAR23907.1 - 4.6e-11 42.4 0.0 1.3e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 CAR23907.1 - 3e-08 33.9 4.7 2.2e-05 24.5 1.7 5.3 3 2 0 5 5 5 2 AAA domain SMC_N PF02463.14 CAR23907.1 - 4e-08 32.7 0.1 4e-08 32.7 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR23907.1 - 0.00039 19.8 0.0 0.00099 18.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CAR23907.1 - 0.075 13.1 0.0 0.075 13.1 0.0 5.9 4 3 0 5 5 5 0 AAA domain AAA_19 PF13245.1 CAR23907.1 - 0.1 12.3 0.1 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain FGGY_C PF02782.11 CAR23908.1 - 2.3e-21 76.3 0.0 3.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CAR23908.1 - 4.3e-05 22.9 0.0 7.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 CAR23908.1 - 0.12 11.6 0.0 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family RNA_pol_I_A49 PF06870.7 CAR23909.1 - 1.4e-137 458.3 0.7 1.6e-137 458.2 0.5 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DnaJ PF00226.26 CAR23910.1 - 9e-18 63.7 0.2 1.3e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CAR23910.1 - 1.3e-14 53.4 2.2 2.2e-14 52.7 1.6 1.4 1 0 0 1 1 1 1 CSL zinc finger Aegerolysin PF06355.8 CAR23910.1 - 0.12 12.2 0.7 2.3 8.0 0.5 2.1 1 1 0 1 1 1 0 Aegerolysin LCAT PF02450.10 CAR23911.1 - 2.3e-07 30.1 0.0 4.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 CAR23911.1 - 9.2e-07 28.6 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CAR23911.1 - 5.1e-06 26.5 0.0 8.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR23911.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR23911.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 CAR23911.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF900 PF05990.7 CAR23911.1 - 0.002 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 CAR23911.1 - 0.0048 16.5 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 CAR23911.1 - 0.099 12.0 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) tRNA-synt_1e PF01406.14 CAR23912.1 - 2.4e-140 466.9 0.1 2.4e-140 466.9 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CAR23912.1 - 8.2e-08 31.3 0.6 1.1e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CAR23912.1 - 9.9e-07 27.1 1.2 5.6e-06 24.6 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) NAP PF00956.13 CAR23913.1 - 2.1e-22 79.4 0.8 3e-22 78.9 0.6 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) CWC25 PF12542.3 CAR23914.1 - 1.5e-17 63.8 1.8 1.5e-17 63.8 1.3 2.1 1 1 1 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.4 CAR23914.1 - 3.5e-12 46.1 10.3 3.5e-12 46.1 7.2 2.0 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR SUI1 PF01253.17 CAR23915.1 - 1.4e-27 95.2 1.9 1.9e-27 94.8 1.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 ANTH PF07651.11 CAR23916.1 - 3.9e-71 239.0 0.0 3.9e-71 239.0 0.0 2.8 2 1 1 3 3 3 1 ANTH domain Zn_clus PF00172.13 CAR23918.1 - 3.8e-06 26.7 9.2 8.8e-06 25.5 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex2_Pex12 PF04757.9 CAR23919.1 - 2.1e-07 30.5 12.3 1e-06 28.3 8.5 2.0 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CAR23919.1 - 0.79 9.7 12.2 1.4 9.0 8.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Endonuclease_NS PF01223.18 CAR23921.1 - 1.9e-57 194.2 0.0 2.3e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease KRTAP7 PF15034.1 CAR23922.1 - 0.36 11.5 2.0 1.2 9.8 1.4 1.9 1 0 0 1 1 1 0 KRTAP type 7 family RNase_H2_suC PF08615.6 CAR23923.1 - 4e-14 52.6 0.0 1.9e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Orthopox_F8 PF05886.6 CAR23923.1 - 0.021 14.6 0.1 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus F8 protein LRR_4 PF12799.2 CAR23924.1 - 0.051 13.2 9.0 1.6 8.4 1.4 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Sec10 PF07393.6 CAR23925.1 - 4.3e-51 173.9 20.1 5.8e-51 173.5 13.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 PRP21_like_P PF12230.3 CAR23926.1 - 4.1e-39 134.4 7.9 6.5e-39 133.7 5.5 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CAR23926.1 - 8.1e-17 60.6 2.7 8.6e-10 38.1 1.2 2.7 2 1 0 2 2 2 2 Surp module Rep_fac-A_C PF08646.5 CAR23926.1 - 0.54 9.9 4.4 0.11 12.1 0.3 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain CRAL_TRIO_2 PF13716.1 CAR23927.1 - 2.5e-33 115.1 0.7 4.8e-33 114.1 0.5 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CAR23927.1 - 1e-05 25.1 0.0 3.5e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CAR23928.1 - 4.2e-47 160.3 1.2 1.3e-46 158.6 0.9 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CAR23928.1 - 2.4e-16 59.6 0.6 1.5e-15 57.2 0.1 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 CAR23928.1 - 1.7e-05 24.0 0.0 5e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CAR23928.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Aconitase PF00330.15 CAR23929.1 - 8.6e-176 584.9 0.0 1.8e-175 583.8 0.0 1.6 2 0 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CAR23929.1 - 9.2e-42 142.2 0.0 1.6e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SPX PF03105.14 CAR23931.1 - 2.4e-46 158.7 9.7 3.3e-46 158.2 6.7 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CAR23931.1 - 7.3e-24 84.4 42.8 1.1e-23 83.9 29.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CAR23931.1 - 1.7e-16 59.7 25.7 1.7e-16 59.7 17.8 2.2 1 1 1 2 2 2 1 Citrate transporter UCH PF00443.24 CAR23932.1 - 1.1e-84 283.7 0.0 3.4e-84 282.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR23932.1 - 6e-20 71.8 3.9 1.6e-12 47.4 0.2 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CAR23932.1 - 6.2e-07 29.7 0.1 2e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 DUSP domain PfkB PF00294.19 CAR23933.1 - 2.7e-49 167.9 0.3 3.7e-49 167.5 0.2 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RNase_PH PF01138.16 CAR23934.1 - 6.4e-28 97.7 0.9 5e-26 91.5 0.6 2.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 ELO PF01151.13 CAR23935.1 - 3.4e-61 206.7 23.9 4.1e-61 206.4 16.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Myb_DNA-binding PF00249.26 CAR23936.1 - 7.5e-15 54.7 0.0 2.5e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR23936.1 - 1.2e-05 25.2 0.2 0.02 15.0 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain AAA PF00004.24 CAR23937.1 - 2.2e-09 37.6 1.1 1.3e-08 35.0 0.1 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR23937.1 - 2.6e-09 37.3 0.0 1.3e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.6 CAR23937.1 - 3.6e-07 29.8 0.0 1.2e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 CDC6, C terminal AAA_16 PF13191.1 CAR23937.1 - 4.3e-07 30.0 0.1 3.9e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 CAR23937.1 - 6.6e-05 22.7 0.3 0.00027 20.7 0.0 2.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 CAR23937.1 - 0.001 18.7 0.1 0.004 16.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 CAR23937.1 - 0.0086 15.0 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 CAR23937.1 - 0.012 15.1 1.0 1.1 8.8 0.5 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CAR23937.1 - 0.015 15.2 0.5 2.4 8.0 0.1 3.1 2 1 0 2 2 2 0 AAA domain Beach PF02138.13 CAR23938.1 - 4.2e-110 367.4 0.1 7.6e-110 366.5 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CAR23938.1 - 8.7e-12 44.8 0.0 2.6e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Ribosomal_S11 PF00411.14 CAR23940.1 - 5.4e-41 139.2 0.8 6.5e-41 138.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S8 PF00410.14 CAR23941.1 - 2.6e-26 91.9 0.1 3.5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Pkinase PF00069.20 CAR23942.1 - 4.1e-45 153.9 0.0 5.8e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23942.1 - 2e-27 95.9 0.0 3.3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR23942.1 - 0.062 13.0 0.2 5.4 6.6 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Mannosyl_trans3 PF11051.3 CAR23943.1 - 8e-81 271.3 0.0 1e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 CAR23943.1 - 0.0011 18.3 0.4 0.021 14.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 8 Epimerase PF01370.16 CAR23946.1 - 2.1e-22 79.6 0.0 2.8e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR23946.1 - 4.5e-18 64.9 0.0 5.8e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CAR23946.1 - 1.3e-15 56.9 0.1 4.3e-15 55.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CAR23946.1 - 9.2e-08 32.2 0.2 2.2e-07 31.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CAR23946.1 - 6.3e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CAR23946.1 - 4.1e-06 25.9 0.1 7.3e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CAR23946.1 - 1.3e-05 24.9 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CAR23946.1 - 0.00017 20.9 0.0 0.0061 15.8 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 CAR23946.1 - 0.013 14.4 0.0 0.056 12.3 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain AA_permease PF00324.16 CAR23947.1 - 5.4e-98 328.4 39.8 6.1e-98 328.2 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23947.1 - 9.7e-28 96.8 42.2 1.3e-27 96.4 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_3 PF00202.16 CAR23948.1 - 2.8e-55 187.5 0.0 3.4e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III muHD PF10291.4 CAR23949.1 - 4.9e-73 245.4 0.0 4.9e-73 245.4 0.0 1.6 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain CorA PF01544.13 CAR23949.1 - 0.025 13.6 0.6 0.13 11.2 0.8 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2811 PF10929.3 CAR23949.1 - 0.031 14.3 0.1 0.37 10.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) PAT1 PF09770.4 CAR23949.1 - 8.5 4.4 32.0 13 3.8 22.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SSB PF00436.20 CAR23951.1 - 6e-19 67.8 0.0 7.2e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Gon7 PF08738.5 CAR23952.1 - 2.2e-33 114.3 0.2 2.8e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Gon7 family AF1Q PF15017.1 CAR23952.1 - 0.015 15.1 1.2 0.023 14.5 0.9 1.2 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator DUF2713 PF10897.3 CAR23952.1 - 0.092 11.9 0.8 0.12 11.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) DUF4611 PF15387.1 CAR23952.1 - 0.35 11.0 10.2 0.93 9.6 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) MFS_1 PF07690.11 CAR23953.1 - 4.7e-27 94.6 18.7 7.5e-27 93.9 13.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.2 CAR23953.1 - 8.1 6.3 12.8 0.047 13.5 1.1 3.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3792) Glyco_transf_34 PF05637.7 CAR23954.1 - 2.3e-53 181.1 0.0 3.2e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF244 PF03112.9 CAR23954.1 - 0.027 13.9 0.3 0.067 12.7 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF ATP12 PF07542.6 CAR23955.1 - 7.5e-31 106.6 0.0 1.4e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Hom_end PF05204.9 CAR23955.1 - 0.094 12.6 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Homing endonuclease Prefoldin_2 PF01920.15 CAR23956.1 - 2.9e-14 52.7 10.5 3.4e-14 52.4 7.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Intein_splicing PF14890.1 CAR23956.1 - 0.0084 15.0 1.6 0.0095 14.8 1.1 1.0 1 0 0 1 1 1 1 Intein splicing domain Meth_synt_2 PF01717.13 CAR23956.1 - 0.0086 15.0 0.7 0.014 14.4 0.2 1.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain DUF948 PF06103.6 CAR23956.1 - 0.0088 15.8 3.6 0.073 12.9 0.3 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF3338 PF11819.3 CAR23956.1 - 0.021 14.2 6.5 0.73 9.2 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3338) Gemini_AL1_M PF08283.6 CAR23956.1 - 0.093 12.5 0.1 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Geminivirus rep protein central domain NPV_P10 PF05531.7 CAR23956.1 - 1.6 9.0 7.0 0.67 10.2 0.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG27 PF09451.5 CAR23957.1 - 1.4e-61 208.1 0.1 1.8e-61 207.7 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 AMIN PF11741.3 CAR23957.1 - 0.03 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 AMIN domain PBP1_TM PF14812.1 CAR23957.1 - 0.053 13.8 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L22 PF00237.14 CAR23958.1 - 1.7e-33 114.6 0.4 2.5e-33 114.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CASP_C PF08172.7 CAR23959.1 - 4.7e-64 215.7 2.8 4.7e-64 215.7 1.9 5.3 1 1 2 3 3 3 1 CASP C terminal DivIC PF04977.10 CAR23959.1 - 0.022 14.2 1.3 0.022 14.2 0.9 7.9 6 2 2 8 8 8 0 Septum formation initiator DUF4618 PF15397.1 CAR23959.1 - 0.081 12.2 0.2 0.081 12.2 0.1 5.4 2 1 1 4 4 4 0 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.4 CAR23959.1 - 0.69 9.7 69.7 0.14 11.9 6.8 6.5 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 CAR23959.1 - 2.3 8.0 67.3 0.31 10.9 0.6 6.2 4 1 1 6 6 6 0 Afadin- and alpha -actinin-Binding SWIRM PF04433.12 CAR23960.1 - 5.5e-32 109.7 0.1 1.4e-31 108.4 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CAR23960.1 - 3.2e-06 27.0 0.0 7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR23960.1 - 6e-06 26.2 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain 7TMR-DISMED2 PF07696.6 CAR23960.1 - 0.012 15.0 1.2 1.8 7.9 0.5 2.6 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 KRE9 PF05390.6 CAR23961.1 - 8e-45 151.6 12.1 8e-45 151.6 8.4 2.8 1 1 1 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CAR23961.1 - 1.4e-10 41.4 2.0 1.4e-10 41.4 1.4 2.7 3 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Wzt_C PF14524.1 CAR23961.1 - 0.08 12.6 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Wzt C-terminal domain Rep_fac-A_3 PF08661.6 CAR23962.1 - 7.8e-26 90.1 0.0 8.6e-26 89.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Cadherin PF00028.12 CAR23962.1 - 0.079 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Cadherin domain Peptidase_M20 PF01546.23 CAR23963.1 - 2.5e-24 85.8 0.0 3.4e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR23963.1 - 9.8e-13 47.8 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain STE3 PF02076.10 CAR23964.1 - 6.7e-92 307.5 15.6 8e-92 307.3 10.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF2401 PF10287.4 CAR23965.1 - 9.3e-93 310.0 2.9 1.3e-92 309.6 2.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CAR23965.1 - 2.8e-22 78.6 0.1 7.1e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SRI PF08236.6 CAR23967.1 - 2.2e-27 94.8 4.1 2.2e-27 94.8 2.9 3.2 2 1 1 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 CAR23967.1 - 5.7e-24 85.2 4.6 1.1e-22 81.0 0.2 3.4 2 1 0 2 2 2 1 SET domain WW PF00397.21 CAR23967.1 - 0.00097 18.9 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 WW domain Zip PF02535.17 CAR23969.1 - 1.6e-28 99.6 13.0 1.9e-27 96.1 9.0 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter CbtA PF09490.5 CAR23969.1 - 0.0037 16.6 1.4 0.013 14.7 0.0 2.4 3 0 0 3 3 3 1 Probable cobalt transporter subunit (CbtA) DUF165 PF02592.10 CAR23969.1 - 0.01 15.9 0.1 0.99 9.5 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 CD20 PF04103.10 CAR23969.1 - 0.44 10.4 7.9 0.23 11.4 0.2 3.2 3 2 0 3 3 3 0 CD20-like family AA_permease PF00324.16 CAR23970.1 - 8.5e-73 245.3 44.8 1.1e-72 244.9 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR23970.1 - 1e-41 142.9 48.6 1.4e-41 142.4 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease p53-inducible11 PF14936.1 CAR23970.1 - 3.1 7.7 10.4 0.094 12.6 0.7 2.7 3 0 0 3 3 3 0 Tumour protein p53-inducible protein 11 GTP_EFTU PF00009.22 CAR23971.1 - 1.7e-35 122.2 0.0 2.5e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CAR23971.1 - 7.2e-16 57.8 0.0 1.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CAR23971.1 - 1.7e-13 50.2 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR23971.1 - 2.4e-05 24.3 0.1 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR23971.1 - 8.1e-05 22.5 0.1 0.00018 21.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR23971.1 - 0.00011 22.6 0.1 0.00024 21.5 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CAR23971.1 - 0.0091 15.2 0.1 0.084 12.0 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PucR PF07905.6 CAR23971.1 - 0.036 13.6 0.1 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family EFG_II PF14492.1 CAR23971.1 - 0.038 13.8 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II Ras PF00071.17 CAR23971.1 - 0.081 12.3 0.1 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Ras family Ebp2 PF05890.7 CAR23972.1 - 1.4e-85 286.8 27.2 1.4e-85 286.8 18.9 2.8 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.12 CAR23973.1 - 1.8e-82 276.0 0.0 2.2e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase UcrQ PF02939.11 CAR23974.1 - 1.8e-35 120.5 0.6 2.1e-35 120.3 0.4 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 CAR23974.1 - 0.087 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) Pkinase PF00069.20 CAR23975.1 - 1e-40 139.5 0.0 5.2e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23975.1 - 1.4e-23 83.3 0.0 1.2e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CAR23975.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_L14 PF00238.14 CAR23976.1 - 7.1e-44 148.4 2.6 7.9e-44 148.3 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.20 CAR23977.1 - 3e-50 170.7 0.0 4.9e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23977.1 - 2.7e-20 72.5 0.0 5.2e-20 71.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23977.1 - 0.0057 15.6 0.0 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR23977.1 - 0.0074 15.3 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CAR23977.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CAR23977.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CAR23977.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LrgB PF04172.11 CAR23978.1 - 3.2e-21 75.4 4.0 3.2e-21 75.4 2.8 2.7 2 2 0 2 2 2 1 LrgB-like family LrgA PF03788.9 CAR23978.1 - 0.0029 17.2 2.9 0.0029 17.2 2.0 2.4 2 0 0 2 2 2 1 LrgA family L51_S25_CI-B8 PF05047.11 CAR23979.1 - 9e-14 50.9 0.0 1.7e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Arf PF00025.16 CAR23979.1 - 0.056 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Na_H_Exchanger PF00999.16 CAR23980.1 - 2.6e-33 115.1 37.8 8.5e-22 77.1 18.5 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Pkinase PF00069.20 CAR23982.1 - 2.9e-70 236.3 0.0 3.7e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR23982.1 - 1.5e-40 138.9 0.0 2e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR23982.1 - 0.0004 19.4 0.0 0.00077 18.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CAR23982.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 CAR23983.1 - 1.9e-18 66.2 37.4 3.2e-17 62.2 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PigN PF04987.9 CAR23984.1 - 1.1e-133 446.1 40.2 1.5e-133 445.7 27.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CAR23984.1 - 2.3e-14 53.4 0.2 2.2e-10 40.4 0.0 2.1 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CAR23984.1 - 1.8e-10 40.5 0.0 6.2e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CAR23984.1 - 0.0077 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2556 PF10831.3 CAR23984.1 - 0.051 13.2 1.2 0.23 11.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2556) DnaJ PF00226.26 CAR23985.1 - 1.8e-20 72.3 0.3 5e-20 71.0 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain PIR PF00399.14 CAR23987.1 - 1.1e-56 186.4 125.5 1.2e-07 30.8 7.2 8.6 8 0 0 8 8 8 8 Yeast PIR protein repeat Alkyl_sulf_dimr PF14863.1 CAR23987.1 - 1.6 8.9 4.3 12 6.1 1.1 2.6 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation TFIIA PF03153.8 CAR23987.1 - 4.8 6.9 17.5 6.4 6.5 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIR PF00399.14 CAR23988.1 - 2.4e-63 207.5 147.6 1.2e-07 30.7 3.7 9.6 9 0 0 9 9 9 9 Yeast PIR protein repeat Alkyl_sulf_dimr PF14863.1 CAR23988.1 - 4.7 7.4 7.4 8.8 6.5 0.6 2.7 1 1 3 4 4 4 0 Alkyl sulfatase dimerisation PIR PF00399.14 CAR23989.1 - 3.5e-11 42.0 22.3 7.1e-06 25.1 2.8 2.8 2 0 0 2 2 2 2 Yeast PIR protein repeat zf-RING_2 PF13639.1 CAR23990.1 - 0.00081 19.1 7.0 0.0019 17.9 4.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR23990.1 - 0.13 11.8 5.6 0.42 10.3 3.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CAR23990.1 - 0.16 11.7 0.8 0.73 9.6 0.5 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger Peptidase_S64 PF08192.6 CAR23991.1 - 1.9e-255 849.5 0.0 2.1e-255 849.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S64 XhlA PF10779.4 CAR23991.1 - 1.6 8.6 5.8 13 5.8 0.3 2.5 2 0 0 2 2 2 0 Haemolysin XhlA 6PF2K PF01591.13 CAR23992.1 - 3.1e-82 274.9 0.0 4.4e-82 274.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CAR23992.1 - 4.3e-32 111.3 0.1 7.8e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CAR23992.1 - 9.5e-06 25.5 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR23992.1 - 0.0033 18.2 0.1 0.026 15.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 CAR23992.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Vps35 PF03635.12 CAR23993.1 - 6.8e-273 907.4 18.1 8e-273 907.1 12.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 peroxidase PF00141.18 CAR23994.1 - 5.9e-46 156.8 0.0 1e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Pam17 PF08566.5 CAR23995.1 - 1.8e-70 236.1 0.4 2.2e-70 235.8 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 MFS_1 PF07690.11 CAR23995.1 - 0.0011 17.8 0.1 0.0013 17.5 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Pmp3 PF01679.12 CAR23996.1 - 6.5e-19 67.3 4.2 8.1e-19 67.0 2.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4131 PF13567.1 CAR23996.1 - 0.045 13.1 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) F-box-like PF12937.2 CAR23997.1 - 4.8e-09 35.8 0.5 1.7e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CAR23997.1 - 1.8e-05 24.2 1.3 4.3e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 F-box domain Zn_clus PF00172.13 CAR23998.1 - 2e-08 33.9 6.8 5.3e-08 32.6 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Las1 PF04031.8 CAR23999.1 - 7.2e-49 165.4 0.0 1.3e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Las1-like RNA_polI_A34 PF08208.6 CAR24000.1 - 1.7e-20 73.5 38.0 2.9e-20 72.7 0.0 2.0 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.4 CAR24000.1 - 0.025 14.0 16.0 0.028 13.9 11.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med19 PF10278.4 CAR24000.1 - 0.03 14.0 29.2 0.044 13.4 20.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.9 CAR24000.1 - 0.049 11.6 6.2 0.046 11.7 4.3 1.0 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 CAR24000.1 - 0.061 13.2 8.3 0.065 13.1 5.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CAR24000.1 - 0.55 10.0 11.8 0.6 9.9 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 CAR24000.1 - 0.58 9.4 14.6 0.7 9.2 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 CAR24000.1 - 0.61 9.8 5.7 0.6 9.8 3.9 1.1 1 0 0 1 1 1 0 DDHD domain Herpes_DNAp_acc PF04929.7 CAR24000.1 - 1.4 7.8 12.2 1.6 7.6 8.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIE_beta PF02186.10 CAR24001.1 - 5.2e-24 84.0 0.6 1e-23 83.0 0.4 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain FIBP PF05427.6 CAR24002.1 - 0.067 12.4 0.3 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) CRAL_TRIO PF00650.15 CAR24004.1 - 2.4e-24 85.6 0.1 3.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CAR24004.1 - 2.6e-07 30.6 0.1 9.6e-07 28.8 0.1 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.1 CAR24004.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin BATS PF06968.8 CAR24005.1 - 1.6e-27 95.1 0.1 4.6e-27 93.7 0.0 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CAR24005.1 - 3.6e-17 63.0 0.1 1.3e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Tim17 PF02466.14 CAR24007.1 - 2.2e-31 108.5 4.3 2.6e-31 108.3 3.0 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 CAR24008.1 - 4.5e-51 173.4 0.0 1.1e-50 172.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24008.1 - 5.3e-20 71.5 0.0 8.1e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR24008.1 - 0.0034 17.1 0.1 0.0066 16.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAR24008.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 CAR24008.1 - 0.13 11.8 0.8 0.4 10.2 0.0 2.1 3 0 0 3 3 3 0 Choline/ethanolamine kinase RNA_pol_Rpb4 PF03874.11 CAR24009.1 - 9e-35 119.2 5.1 1.7e-34 118.2 3.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb4 Vezatin PF12632.2 CAR24009.1 - 0.029 13.4 1.9 0.038 13.0 1.3 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Ribonuc_L-PSP PF01042.16 CAR24009.1 - 0.096 12.4 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Endoribonuclease L-PSP Glyco_transf_15 PF01793.11 CAR24010.1 - 7.8e-133 442.5 7.9 9.3e-133 442.2 5.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L1 PF00687.16 CAR24011.1 - 1.5e-44 151.9 0.9 1.9e-44 151.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cohesin_HEAT PF12765.2 CAR24011.1 - 0.037 14.0 0.1 4.1 7.4 0.0 2.7 2 1 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DEAD PF00270.24 CAR24012.1 - 2.4e-43 147.5 1.3 5.4e-43 146.3 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR24012.1 - 9.1e-28 95.9 0.4 1e-26 92.5 0.1 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR24012.1 - 0.00011 22.0 0.0 0.00046 20.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CAR24012.1 - 0.0043 16.7 0.9 0.077 12.7 0.1 2.6 3 0 0 3 3 3 1 Part of AAA domain CMS1 PF14617.1 CAR24012.1 - 0.053 12.5 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 CAR24012.1 - 0.06 12.9 0.2 0.35 10.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.1 CAR24012.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Glyco_transf_8 PF01501.15 CAR24013.1 - 2.3e-28 99.2 0.0 3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ribosomal_S21e PF01249.13 CAR24014.1 - 4e-40 135.6 0.0 4.4e-40 135.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e UPF0302 PF08864.5 CAR24014.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 UPF0302 domain tRNA_U5-meth_tr PF05958.6 CAR24015.1 - 7.6e-23 80.7 0.1 1.8e-21 76.2 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 CAR24015.1 - 9.9e-12 44.4 0.0 3.5e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 TRAM domain Methyltransf_31 PF13847.1 CAR24015.1 - 1.5e-09 37.6 0.2 3.2e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR24015.1 - 4.4e-07 30.4 0.0 8.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CAR24015.1 - 1.1e-05 24.7 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CAR24015.1 - 4.9e-05 22.7 0.0 8.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CAR24015.1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CAR24015.1 - 0.0002 20.9 0.2 0.00035 20.1 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 CAR24015.1 - 0.00045 19.6 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.11 CAR24015.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 CAR24015.1 - 0.013 15.8 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CAR24015.1 - 0.034 14.6 0.0 0.09 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CAR24015.1 - 0.041 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CAR24015.1 - 0.056 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 CAR24015.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ras PF00071.17 CAR24016.1 - 1.1e-48 164.6 0.0 1.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR24016.1 - 5e-16 59.2 0.0 9.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR24016.1 - 3e-05 23.3 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DHC_N1 PF08385.7 CAR24017.1 - 8.3e-91 305.1 1.9 8.3e-91 305.1 1.3 4.4 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CAR24017.1 - 1.5e-85 287.2 4.8 1.5e-85 287.2 3.3 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CAR24017.1 - 3.3e-67 226.3 0.0 7.7e-67 225.1 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 CAR24017.1 - 1.5e-50 171.9 0.6 1.2e-49 169.0 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 CAR24017.1 - 4.2e-30 104.6 2.7 8e-30 103.7 1.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 CAR24017.1 - 5.4e-27 94.4 0.0 1.1e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CAR24017.1 - 8.5e-27 93.4 0.0 6.7e-26 90.5 0.0 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CAR24017.1 - 3.1e-22 78.8 0.0 1.1e-09 38.0 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 CAR24017.1 - 7.8e-19 67.8 0.0 1.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA PF00004.24 CAR24017.1 - 1.5e-17 64.0 1.0 0.00028 21.1 0.0 6.8 5 1 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR24017.1 - 1.2e-12 48.0 2.5 0.1 12.7 0.0 6.8 7 0 0 7 7 5 3 AAA domain AAA_16 PF13191.1 CAR24017.1 - 1.8e-09 37.8 0.1 0.039 13.9 0.0 5.7 4 1 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.1 CAR24017.1 - 1e-08 35.5 0.5 0.021 15.1 0.0 5.5 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CAR24017.1 - 2.9e-08 33.3 0.1 0.035 13.8 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain AAA_17 PF13207.1 CAR24017.1 - 1.3e-07 32.3 2.5 0.36 11.6 0.0 5.7 5 0 0 5 5 4 2 AAA domain Zeta_toxin PF06414.7 CAR24017.1 - 1.1e-06 27.8 0.6 0.078 12.0 0.0 4.8 6 0 0 6 6 4 2 Zeta toxin T2SE PF00437.15 CAR24017.1 - 6.4e-05 21.9 0.1 0.057 12.3 0.0 3.0 4 0 0 4 4 3 2 Type II/IV secretion system protein AAA_33 PF13671.1 CAR24017.1 - 0.00011 22.0 0.1 4.5 7.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 CAR24017.1 - 0.00032 20.3 0.1 1.1 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 CAR24017.1 - 0.0031 16.9 0.1 1.1 8.6 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CAR24017.1 - 0.0067 15.9 0.0 2.5 7.7 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 CAR24017.1 - 0.01 15.2 1.1 3.3 7.0 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.17 CAR24017.1 - 0.013 15.6 0.0 28 4.9 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_11 PF13086.1 CAR24017.1 - 0.024 14.2 10.7 0.75 9.3 0.0 5.1 5 0 0 5 5 3 0 AAA domain Mg_chelatase PF01078.16 CAR24017.1 - 0.032 13.3 0.3 11 5.1 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CAR24017.1 - 0.045 13.7 3.4 4.1 7.3 0.1 3.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 CAR24017.1 - 0.064 12.6 0.0 12 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CAR24017.1 - 0.087 12.5 0.2 2.6 7.7 0.0 3.0 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 CAR24017.1 - 0.11 12.1 0.2 51 3.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain PAP2 PF01569.16 CAR24018.1 - 8.1e-16 57.8 4.8 8.1e-16 57.8 3.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily Mito_carr PF00153.22 CAR24020.1 - 2.6e-61 203.3 1.4 8.1e-22 76.7 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Dicistro_VP4 PF11492.3 CAR24020.1 - 2.2 8.3 5.1 0.91 9.5 0.0 2.9 4 0 0 4 4 4 0 Cricket paralysis virus, VP4 Solute_trans_a PF03619.11 CAR24021.1 - 1.8e-85 286.5 15.3 2.1e-85 286.3 10.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Zn_dep_PLPC PF00882.13 CAR24022.1 - 3.8e-18 65.6 0.8 6.7e-18 64.8 0.5 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C FG-GAP PF01839.18 CAR24022.1 - 2.3e-05 23.9 1.8 0.0052 16.4 0.1 3.8 3 0 0 3 3 3 1 FG-GAP repeat VCBS PF13517.1 CAR24022.1 - 0.027 14.8 1.6 0.098 13.0 0.1 2.7 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PPR_3 PF13812.1 CAR24022.1 - 0.097 13.0 0.0 0.54 10.6 0.0 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain mIF3 PF14877.1 CAR24023.1 - 1.1e-66 223.6 10.2 1.1e-66 223.6 7.1 2.6 3 0 0 3 3 3 1 Mitochondrial translation initiation factor IF3_C PF00707.17 CAR24023.1 - 0.00051 19.7 0.8 0.0028 17.3 0.1 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain SusE PF14292.1 CAR24023.1 - 0.039 13.7 1.6 6.1 6.6 0.1 3.0 3 0 0 3 3 3 0 SusE outer membrane protein CPSase_L_D2 PF02786.12 CAR24024.1 - 1.1e-112 374.5 1.8 1.8e-83 279.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CAR24024.1 - 3.8e-46 155.8 0.0 9.3e-46 154.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CAR24024.1 - 4.6e-43 146.8 0.0 9.8e-43 145.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 CAR24024.1 - 2e-41 140.9 0.0 4.1e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 CAR24024.1 - 3.7e-40 136.4 0.4 1.2e-19 70.3 0.0 3.2 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CAR24024.1 - 4.9e-40 136.1 0.3 1.9e-39 134.2 0.1 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 CAR24024.1 - 7.3e-35 120.1 0.3 7.6e-34 116.8 0.0 3.0 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CAR24024.1 - 2.7e-33 115.2 0.6 8.4e-22 77.7 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAR24024.1 - 1.4e-23 83.1 0.3 1e-13 50.7 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CAR24024.1 - 1.3e-22 79.4 0.0 8.7e-22 76.8 0.0 2.6 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 CAR24024.1 - 1.3e-14 54.0 3.0 1.5e-08 34.2 0.4 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CAR24024.1 - 4.7e-14 52.1 0.6 1.3e-06 27.8 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 CAR24024.1 - 2e-06 27.3 0.0 5.4e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CAR24024.1 - 5.7e-06 26.2 1.4 0.029 14.2 0.2 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 CAR24024.1 - 0.012 15.1 0.0 0.037 13.4 0.0 1.8 1 0 0 1 1 1 0 DJ-1/PfpI family TrkH PF02386.11 CAR24025.1 - 1.1e-137 458.4 7.3 1.1e-137 458.4 5.0 2.1 2 0 0 2 2 2 2 Cation transport protein Pkinase PF00069.20 CAR24026.1 - 1.3e-53 181.7 0.0 1.7e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24026.1 - 4.3e-37 127.5 0.0 5.8e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR24026.1 - 6.5e-05 22.0 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PNGaseA PF12222.3 CAR24027.1 - 2.7e-60 204.4 2.4 4.9e-59 200.2 1.7 2.1 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A OapA_N PF08525.6 CAR24027.1 - 0.012 15.3 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif zf-H2C2 PF09337.5 CAR24028.1 - 8.3e-20 69.9 4.4 1.8e-19 68.8 3.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 CAR24028.1 - 0.00036 20.4 0.0 0.00093 19.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR24028.1 - 0.00069 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CAR24028.1 - 0.0053 16.9 0.0 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain POTRA_2 PF08479.6 CAR24028.1 - 0.051 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 POTRA domain, ShlB-type CN_hydrolase PF00795.17 CAR24029.1 - 2.9e-25 88.6 0.0 3.9e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCD14 PF08704.5 CAR24030.1 - 1.5e-81 273.5 0.8 2.3e-45 155.0 0.1 2.3 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 CAR24030.1 - 7.7e-06 25.1 0.0 1.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CAR24030.1 - 9.7e-06 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR24030.1 - 8.2e-05 23.1 0.0 0.00022 21.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR24030.1 - 0.00071 19.1 0.0 0.0051 16.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR24030.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 CAR24030.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3748 PF12566.3 CAR24030.1 - 0.037 13.9 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) ABC_tran_2 PF12848.2 CAR24030.1 - 0.08 12.7 2.7 0.23 11.3 1.9 1.8 1 0 0 1 1 1 0 ABC transporter FERM_M PF00373.13 CAR24030.1 - 0.18 11.9 0.7 0.4 10.8 0.5 1.5 1 1 0 1 1 1 0 FERM central domain LSM PF01423.17 CAR24031.1 - 9.8e-14 50.6 0.1 1.5e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain PUF PF00806.14 CAR24031.1 - 0.063 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DUF1687 PF07955.6 CAR24032.1 - 1.2e-30 106.2 0.2 1.5e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Pyridox_oxidase PF01243.15 CAR24032.1 - 0.11 12.5 0.0 1.8 8.6 0.0 2.1 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF2413 PF10310.4 CAR24033.1 - 9.4e-115 383.9 14.4 1.1e-114 383.7 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Alb1 PF09135.6 CAR24034.1 - 4.9e-21 75.4 8.7 7.3e-21 74.8 6.1 1.2 1 0 0 1 1 1 1 Alb1 Ribul_P_3_epim PF00834.14 CAR24035.1 - 3.9e-67 225.2 0.1 5e-67 224.9 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 CAR24035.1 - 0.005 16.2 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 CAR24035.1 - 0.051 13.0 0.0 0.28 10.6 0.0 2.0 2 1 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain NAP PF00956.13 CAR24036.1 - 4.6e-80 268.2 7.7 4.6e-80 268.2 5.3 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Sec62 PF03839.11 CAR24037.1 - 0.0077 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 AMMECR1 PF01871.12 CAR24038.1 - 1.1e-34 119.0 0.0 1.3e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Motilin_ghrelin PF04644.7 CAR24039.1 - 4 7.3 8.8 11 5.8 6.1 1.8 1 0 0 1 1 1 0 Motilin/ghrelin Pho86 PF11124.3 CAR24040.1 - 7.4e-84 281.3 1.8 8.4e-84 281.1 1.2 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 CLN6 PF15156.1 CAR24040.1 - 0.0017 17.5 0.4 0.0026 16.9 0.3 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 Lectin_leg-like PF03388.8 CAR24041.1 - 5.5e-09 35.4 0.0 5.1e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Legume-like lectin family Lectin_legB PF00139.14 CAR24041.1 - 1.3e-05 24.7 0.0 4e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Legume lectin domain SH3_1 PF00018.23 CAR24041.1 - 0.06 12.7 0.3 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 SH3 domain His_Phos_1 PF00300.17 CAR24042.1 - 1.3e-27 96.8 0.3 1.7e-27 96.4 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SUN PF03856.8 CAR24044.1 - 1e-104 349.2 18.1 1e-104 349.2 12.5 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Macoilin PF09726.4 CAR24044.1 - 0.13 10.5 3.5 0.12 10.6 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SipA PF09052.5 CAR24044.1 - 0.14 10.4 3.7 0.22 9.8 2.6 1.4 1 0 0 1 1 1 0 Salmonella invasion protein A Mg_trans_NIPA PF05653.9 CAR24045.1 - 3.8e-15 55.6 15.1 4.7e-15 55.3 10.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CAR24045.1 - 0.034 14.1 14.8 0.034 14.1 2.2 2.9 2 0 0 2 2 2 0 EamA-like transporter family ASF1_hist_chap PF04729.8 CAR24046.1 - 2.2e-66 222.2 0.1 3.2e-66 221.7 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Pkinase PF00069.20 CAR24048.1 - 2.6e-51 174.2 0.0 5.2e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24048.1 - 4.1e-20 71.9 0.0 6.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR24048.1 - 0.0073 15.3 0.0 0.061 12.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAR24048.1 - 0.021 14.5 0.0 7.5 6.2 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.14 CAR24049.1 - 7.4e-113 376.9 0.0 8.9e-113 376.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR24049.1 - 0.0035 15.9 0.0 0.024 13.2 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein Adap_comp_sub PF00928.16 CAR24051.1 - 1e-78 264.0 0.4 1.4e-78 263.6 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pribosyl_synth PF14572.1 CAR24052.1 - 8.8e-44 149.4 0.3 1.4e-43 148.7 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CAR24052.1 - 1.1e-35 121.8 0.0 1.2e-34 118.4 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CAR24052.1 - 1.2e-14 54.0 0.0 2.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAR24052.1 - 0.0032 16.7 0.2 0.0055 15.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pkinase PF00069.20 CAR24053.1 - 5.5e-59 199.4 0.0 1.2e-58 198.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24053.1 - 2.9e-23 82.2 0.0 5.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CAR24053.1 - 0.0017 17.7 1.3 0.0051 16.1 0.0 2.2 2 1 1 3 3 3 1 RIO1 family Kinase-like PF14531.1 CAR24053.1 - 0.0017 17.3 0.0 0.0076 15.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CAR24053.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family MBD_C PF14048.1 CAR24053.1 - 0.035 14.6 1.1 0.097 13.2 0.8 1.8 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF21 PF01595.15 CAR24054.1 - 6.2e-31 107.1 0.4 1.7e-30 105.6 0.5 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF21 T4_Gp59_C PF08994.5 CAR24054.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term NAD_Gly3P_dh_N PF01210.18 CAR24055.1 - 7.2e-53 178.5 0.0 1.2e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CAR24055.1 - 1.1e-46 158.2 0.1 2.1e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CAR24055.1 - 0.004 17.5 0.1 0.12 12.8 0.1 2.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 CAR24055.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.7 CAR24055.1 - 0.11 11.8 0.2 0.63 9.3 0.0 2.3 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain Arginosuc_synth PF00764.14 CAR24056.1 - 3.3e-161 536.6 0.0 3.8e-161 536.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 CAR24056.1 - 0.0003 20.3 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CAR24056.1 - 0.00053 19.3 0.0 0.00094 18.5 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CAR24056.1 - 0.0041 15.7 0.1 0.0065 15.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Peptidase_M49 PF03571.10 CAR24057.1 - 3.8e-234 777.8 0.0 1.3e-233 776.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M49 His_Phos_1 PF00300.17 CAR24058.1 - 1.2e-40 139.1 0.0 5.6e-40 137.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-C2H2_4 PF13894.1 CAR24059.1 - 8.4e-06 25.7 2.6 0.034 14.4 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR24059.1 - 6.8e-05 22.9 7.0 0.0013 18.9 0.2 3.0 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 CAR24059.1 - 0.086 12.9 1.1 0.49 10.5 0.9 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CAR24059.1 - 0.13 12.6 3.8 1.1 9.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Phos_pyr_kin PF08543.7 CAR24060.1 - 1.5e-71 240.4 0.0 2e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CAR24060.1 - 4.3e-53 180.1 0.4 6e-53 179.7 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CAR24060.1 - 5.2e-07 29.0 0.0 8.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Asp PF00026.18 CAR24061.1 - 6.6e-63 212.8 2.5 6.6e-63 212.8 1.7 2.3 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR24061.1 - 1.2e-05 25.3 0.0 1.2e-05 25.3 0.0 3.4 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal F-box-like PF12937.2 CAR24062.1 - 2e-14 53.0 0.6 3.9e-14 52.0 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CAR24062.1 - 4.3e-10 38.9 0.1 8.6e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 CAR24062.1 - 0.0075 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 PRANC domain FAD_binding_6 PF00970.19 CAR24063.1 - 2.3e-27 94.9 0.0 3.5e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CAR24063.1 - 7.7e-24 84.3 0.0 1.1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CAR24063.1 - 2.9e-05 24.0 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CAR24063.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF4131 PF13567.1 CAR24063.1 - 0.06 12.7 0.2 0.14 11.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) ALO PF04030.9 CAR24064.1 - 1.6e-99 332.7 0.3 2.3e-99 332.2 0.2 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CAR24064.1 - 6e-28 97.0 0.2 8.7e-28 96.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Tubulin PF00091.20 CAR24065.1 - 1.5e-70 237.3 0.0 2.1e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAR24065.1 - 3.8e-49 165.9 0.1 5.9e-49 165.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Sugar_tr PF00083.19 CAR24066.1 - 1.6e-44 152.2 18.4 1.9e-44 151.9 12.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR24066.1 - 1.5e-21 76.4 32.4 6.5e-18 64.5 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.1 CAR24066.1 - 0.082 12.2 0.4 0.18 11.1 0.3 1.5 1 0 0 1 1 1 0 Negative regulator of p53/TP53 SQS_PSY PF00494.14 CAR24067.1 - 9.6e-39 133.2 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Pept_tRNA_hydro PF01195.14 CAR24068.1 - 4.4e-41 140.3 0.0 5.3e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Gtr1_RagA PF04670.7 CAR24069.1 - 1.7e-95 318.5 2.2 1.7e-95 318.5 1.5 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CAR24069.1 - 1.6e-09 37.3 0.9 2.5e-09 36.7 0.2 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.16 CAR24069.1 - 1.4e-08 34.1 1.1 4.3e-08 32.5 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CAR24069.1 - 5e-08 33.4 0.5 1.3e-07 32.1 0.1 1.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CAR24069.1 - 2.7e-06 27.3 0.0 5.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CAR24069.1 - 0.0077 16.5 0.5 0.019 15.2 0.1 2.0 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 CAR24069.1 - 0.012 15.0 0.2 0.025 14.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 CAR24069.1 - 0.031 13.3 1.3 0.26 10.3 0.1 2.4 1 1 0 2 2 2 0 AIG1 family DUF815 PF05673.8 CAR24069.1 - 0.037 12.9 0.1 0.073 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 CAR24069.1 - 0.052 13.0 4.1 0.15 11.4 1.1 2.6 2 1 0 2 2 2 0 Guanylate kinase AAA_10 PF12846.2 CAR24069.1 - 0.065 12.6 0.2 0.13 11.6 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain SopD PF11047.3 CAR24069.1 - 0.082 11.8 4.5 0.027 13.4 1.0 1.6 2 0 0 2 2 2 0 Salmonella outer protein D Pyr_redox_2 PF07992.9 CAR24070.1 - 6.1e-28 98.0 0.6 5.1e-18 65.6 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR24070.1 - 7.3e-14 51.9 0.1 8.2e-11 42.1 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR24070.1 - 7.2e-12 45.7 0.1 3.1e-05 24.1 0.0 3.4 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR24070.1 - 0.24 11.1 3.7 21 4.8 0.0 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding HSP70 PF00012.15 CAR24071.1 - 6.5e-265 879.7 14.3 7.5e-265 879.5 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR24071.1 - 6e-15 54.6 3.7 6.4e-13 47.9 0.8 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CAR24071.1 - 0.0013 18.4 0.0 0.004 16.8 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CAR24071.1 - 0.0029 16.7 2.6 0.21 10.6 0.1 3.3 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase Gp-FAR-1 PF05823.7 CAR24071.1 - 0.061 13.2 5.7 0.14 12.1 3.9 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2797 PF10977.3 CAR24071.1 - 0.09 12.3 3.1 0.17 11.4 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) FtsA PF14450.1 CAR24071.1 - 0.12 12.1 12.4 1.7 8.4 1.4 4.6 4 1 0 4 4 4 0 Cell division protein FtsA Prp18 PF02840.10 CAR24071.1 - 0.41 10.4 2.7 2.3 8.0 2.0 2.0 2 0 0 2 2 2 0 Prp18 domain Vps55 PF04133.9 CAR24072.1 - 2.4e-45 153.1 5.8 2.8e-45 152.9 4.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2142 PF09913.4 CAR24072.1 - 0.034 12.7 0.3 0.043 12.4 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF1029 PF06269.7 CAR24072.1 - 2.8 8.0 8.4 10 6.1 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1029) DUF2232 PF09991.4 CAR24072.1 - 4.2 6.2 8.7 18 4.1 5.9 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF1049 PF06305.6 CAR24072.1 - 5.5 6.5 7.9 1.5 8.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) FYVE PF01363.16 CAR24073.1 - 8.9e-17 60.7 13.9 8.9e-17 60.7 9.6 3.2 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 CAR24073.1 - 1.2e-10 41.0 2.0 1.2e-10 41.0 1.4 3.8 4 1 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.1 CAR24073.1 - 0.00083 19.0 2.6 0.00083 19.0 1.8 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CAR24073.1 - 0.0011 18.6 2.8 0.0011 18.6 1.9 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR24073.1 - 0.0015 18.5 3.4 0.0015 18.5 2.4 4.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CAR24073.1 - 0.0036 17.2 1.3 0.0036 17.2 0.9 3.1 3 1 1 4 4 4 1 FANCL C-terminal domain zf-rbx1 PF12678.2 CAR24073.1 - 0.0068 16.4 0.3 0.0068 16.4 0.2 3.8 3 1 0 3 3 3 1 RING-H2 zinc finger Mut7-C PF01927.11 CAR24073.1 - 0.11 12.5 0.1 0.11 12.5 0.0 2.2 2 1 1 3 3 3 0 Mut7-C RNAse domain zf-RING_5 PF14634.1 CAR24073.1 - 2.2 8.0 30.9 0.32 10.7 2.2 4.5 4 0 0 4 4 4 0 zinc-RING finger domain Pox_A3L PF05288.6 CAR24073.1 - 3.8 7.3 6.6 16 5.2 0.2 3.5 3 0 0 3 3 3 0 Poxvirus A3L Protein Brix PF04427.13 CAR24074.1 - 2.5e-58 196.8 1.2 2.5e-58 196.8 0.8 1.4 2 0 0 2 2 2 1 Brix domain DEAD PF00270.24 CAR24075.1 - 6.3e-48 162.4 0.0 1.5e-47 161.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR24075.1 - 2e-26 91.6 0.0 4.4e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR24075.1 - 7.4e-06 25.9 0.7 0.00012 21.9 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Otopetrin PF03189.8 CAR24075.1 - 0.12 11.2 2.2 0.38 9.7 0.1 2.0 2 0 0 2 2 2 0 Otopetrin GLTP PF08718.6 CAR24075.1 - 0.24 11.4 3.5 0.99 9.4 0.0 2.9 3 1 0 3 3 3 0 Glycolipid transfer protein (GLTP) BSD PF03909.12 CAR24076.1 - 1e-26 92.4 4.2 3.2e-14 52.3 0.3 3.0 4 0 0 4 4 4 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CAR24076.1 - 1e-24 85.9 0.2 1e-24 85.9 0.1 2.3 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain DUF2286 PF10051.4 CAR24076.1 - 0.0097 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2286) HSP70 PF00012.15 CAR24077.1 - 8.8e-83 278.2 1.6 1.1e-81 274.5 0.5 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CAR24077.1 - 8.8e-12 44.2 0.0 1.3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.14 CAR24077.1 - 0.0008 17.9 0.1 0.014 13.8 0.0 2.1 1 1 1 2 2 2 1 Actin ApbA PF02558.11 CAR24078.1 - 6.8e-29 100.2 0.0 1e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CAR24078.1 - 6.5e-25 87.5 0.0 1e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 CAR24078.1 - 0.0091 15.7 0.1 0.055 13.2 0.0 2.2 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Baculo_PEP_C PF04513.7 CAR24079.1 - 0.0037 17.0 8.8 0.0065 16.2 6.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus IZUMO PF15005.1 CAR24079.1 - 0.32 11.0 1.2 0.64 10.0 0.9 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion DUF904 PF06005.7 CAR24079.1 - 0.45 10.8 8.5 1.8 8.8 5.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 CAR24079.1 - 1.3 8.8 3.8 6.3 6.6 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 CAR24079.1 - 1.7 6.9 10.5 0.042 12.3 2.6 1.6 2 0 0 2 2 2 0 AAA domain RNase_P_p30 PF01876.11 CAR24080.1 - 1e-51 174.1 0.5 1.5e-51 173.5 0.4 1.2 1 0 0 1 1 1 1 RNase P subunit p30 PBD PF00786.23 CAR24082.1 - 0.0012 19.2 0.3 0.0074 16.6 0.0 2.7 3 0 0 3 3 3 1 P21-Rho-binding domain Med21 PF11221.3 CAR24084.1 - 4.6e-47 159.6 6.8 5.3e-47 159.4 4.7 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 CAR24084.1 - 0.00044 19.9 5.5 0.00086 18.9 0.1 2.9 1 1 2 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin PF00261.15 CAR24084.1 - 0.009 15.1 4.4 0.013 14.5 3.0 1.2 1 0 0 1 1 1 1 Tropomyosin DUF3545 PF12065.3 CAR24084.1 - 0.011 15.5 2.3 0.012 15.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Sipho_Gp157 PF05565.6 CAR24084.1 - 0.011 15.3 5.2 0.016 14.7 3.6 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 RuvB_N PF05496.7 CAR24084.1 - 0.019 14.0 0.2 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TMCO5 PF14992.1 CAR24084.1 - 0.032 13.3 7.2 0.043 12.9 4.8 1.4 1 1 0 1 1 1 0 TMCO5 family ISG65-75 PF11727.3 CAR24084.1 - 0.035 13.1 2.4 0.056 12.4 1.7 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein GldM_N PF12081.3 CAR24084.1 - 0.04 13.4 2.8 0.054 13.0 1.8 1.3 1 1 0 1 1 1 0 GldM N-terminal domain Katanin_con80 PF13925.1 CAR24084.1 - 0.066 12.9 0.3 0.066 12.9 0.2 1.5 2 0 0 2 2 2 0 con80 domain of Katanin DUF4047 PF13256.1 CAR24084.1 - 0.096 12.6 1.8 0.13 12.2 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF148 PF02520.12 CAR24084.1 - 0.11 12.2 3.6 0.15 11.8 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF148 HAP1_N PF04849.8 CAR24084.1 - 0.12 11.2 8.1 0.22 10.4 5.6 1.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region GBP_C PF02841.9 CAR24084.1 - 0.27 10.3 5.2 0.34 10.0 3.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain APG6 PF04111.7 CAR24084.1 - 0.32 9.9 7.4 0.43 9.5 5.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 CAR24084.1 - 0.38 9.9 8.4 0.49 9.5 4.2 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 CAR24084.1 - 0.62 9.5 6.6 0.82 9.1 4.6 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4404 PF14357.1 CAR24084.1 - 0.72 10.3 6.0 1.3 9.5 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF1492 PF07374.6 CAR24084.1 - 4.9 7.3 7.9 17 5.5 1.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) COG2 PF06148.6 CAR24084.1 - 5.5 6.8 7.0 5.4 6.9 2.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.7 CAR24084.1 - 7.1 7.0 14.3 2.1e+02 2.3 0.8 3.2 1 1 1 2 2 2 0 SlyX MIR PF02815.14 CAR24085.1 - 1.1e-18 67.5 0.1 1.7e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 MIR domain PMT PF02366.13 CAR24085.1 - 2.1e-15 56.7 16.3 2.1e-15 56.7 11.3 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ins145_P3_rec PF08709.6 CAR24085.1 - 0.0013 17.7 0.1 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF569 PF04601.8 CAR24085.1 - 0.066 12.6 0.0 0.35 10.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF569) LRR_8 PF13855.1 CAR24087.1 - 0.00038 20.1 0.6 1.7 8.4 0.1 4.5 4 1 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 CAR24087.1 - 0.022 14.3 0.7 63 3.3 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CAR24087.1 - 1.2 9.4 4.9 3e+02 2.0 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich repeat HIT PF01230.18 CAR24088.1 - 5.9e-26 90.8 1.2 5.9e-26 90.8 0.8 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CAR24088.1 - 5.6e-08 33.0 1.4 8e-08 32.5 1.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CAR24088.1 - 0.041 13.5 0.2 0.073 12.7 0.1 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Imm47 PF15586.1 CAR24088.1 - 0.082 12.7 0.2 0.21 11.4 0.0 1.9 2 1 0 2 2 2 0 Immunity protein 47 IGR PF09597.5 CAR24089.1 - 2.4e-25 88.1 0.2 3.5e-25 87.6 0.2 1.2 1 0 0 1 1 1 1 IGR protein motif Fip1 PF05182.8 CAR24090.1 - 2.4e-24 84.3 0.5 4.4e-24 83.4 0.3 1.5 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.7 CAR24090.1 - 0.076 11.3 11.8 0.082 11.2 8.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 CAR24090.1 - 0.32 9.4 7.6 0.31 9.4 5.3 1.1 1 0 0 1 1 1 0 Daxx Family Anillin PF08174.6 CAR24091.1 - 2.7e-16 59.8 0.4 1.1e-15 57.8 0.2 2.2 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 CAR24091.1 - 5.7e-05 23.2 1.0 0.00028 21.0 0.0 2.8 2 0 0 2 2 2 1 PH domain PUF PF00806.14 CAR24092.1 - 5.3e-30 101.1 0.7 7.4e-05 22.0 0.0 6.7 7 0 0 7 7 6 5 Pumilio-family RNA binding repeat RRM_5 PF13893.1 CAR24092.1 - 7.6e-08 32.0 0.0 1.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 CAR24092.1 - 1.6e-05 23.4 4.6 1.6e-05 23.4 3.2 2.1 2 1 0 2 2 1 1 Transmembrane protein RRM_1 PF00076.17 CAR24092.1 - 2.8e-05 23.6 0.0 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mem_trans PF03547.13 CAR24092.1 - 0.0028 16.0 0.6 0.004 15.4 0.4 1.3 1 0 0 1 1 1 1 Membrane transport protein FLO_LFY PF01698.11 CAR24092.1 - 0.025 13.4 13.0 0.041 12.7 9.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Spore_coat_CotO PF14153.1 CAR24092.1 - 0.037 13.4 22.9 0.063 12.7 15.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RRM_6 PF14259.1 CAR24092.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ycf1 PF05758.7 CAR24092.1 - 0.078 10.6 15.7 0.11 10.1 10.9 1.1 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 CAR24092.1 - 0.49 9.5 22.4 1.1 8.4 15.5 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Utp14 PF04615.8 CAR24092.1 - 0.5 8.4 24.2 0.8 7.8 16.7 1.2 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.4 CAR24092.1 - 1.4 7.0 61.9 3.6 5.7 42.9 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CAR24092.1 - 2.3 5.8 26.8 3.7 5.1 18.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 CAR24092.1 - 4.4 6.1 21.3 7.2 5.4 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.17 CAR24092.1 - 4.9 6.0 14.5 4.8 6.0 8.9 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter PPP4R2 PF09184.6 CAR24092.1 - 5.5 6.4 17.7 12 5.3 12.0 1.8 2 0 0 2 2 2 0 PPP4R2 Tim54 PF11711.3 CAR24092.1 - 8.8 4.7 15.3 12 4.3 9.9 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.8 CAR24092.1 - 9.4 5.6 22.1 23 4.4 15.3 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain F-box-like PF12937.2 CAR24093.1 - 3.8e-07 29.7 0.4 1.1e-06 28.2 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR24093.1 - 0.0003 20.3 0.3 0.00094 18.7 0.2 2.0 1 0 0 1 1 1 1 F-box domain AsnA PF03590.10 CAR24093.1 - 0.032 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartate-ammonia ligase BIR PF00653.16 CAR24094.1 - 1.5e-18 66.9 8.3 9.1e-11 42.0 0.4 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.14 CAR24094.1 - 0.00097 18.5 37.9 0.035 13.7 0.9 4.6 4 0 0 4 4 4 4 AT hook motif eIF-5_eIF-2B PF01873.12 CAR24095.1 - 2e-42 143.8 0.0 4e-42 142.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CAR24095.1 - 3.1e-28 97.5 3.0 1.8e-27 95.0 0.0 2.8 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon TPR_8 PF13181.1 CAR24096.1 - 5.6e-05 22.6 0.2 5.6e-05 22.6 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAR24096.1 - 0.00027 20.5 2.6 0.014 15.0 2.0 2.6 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 CAR24096.1 - 0.00053 19.4 1.6 0.00093 18.7 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR24096.1 - 0.0016 19.0 1.6 0.29 11.8 0.7 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR24096.1 - 0.004 16.9 0.4 0.004 16.9 0.3 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR24096.1 - 0.0045 17.5 1.1 0.059 14.0 0.3 3.1 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR24096.1 - 0.025 14.8 3.1 0.091 13.1 0.5 3.2 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAR24096.1 - 0.035 14.2 1.2 1.7 9.0 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR24096.1 - 0.31 11.5 4.8 42 4.8 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAR24096.1 - 6.3 6.8 7.3 2.3 8.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TIP41 PF04176.8 CAR24097.1 - 2.9e-74 248.2 1.5 4.2e-74 247.7 1.0 1.2 1 0 0 1 1 1 1 TIP41-like family PT-TG PF14449.1 CAR24097.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Pre-toxin TG Evr1_Alr PF04777.8 CAR24098.1 - 5.7e-24 83.8 0.5 1.3e-23 82.7 0.3 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 CAR24098.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 1 0 1 1 1 0 The BURPS668_1122 family of deaminases G-gamma PF00631.17 CAR24099.1 - 1.1e-22 79.4 0.0 1.4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF896 PF05979.7 CAR24099.1 - 0.13 11.8 0.8 0.19 11.3 0.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Tmemb_14 PF03647.8 CAR24100.1 - 1e-25 89.9 6.4 1.1e-25 89.8 4.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 CAR24100.1 - 0.0084 16.3 0.9 0.0096 16.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) PCI PF01399.22 CAR24101.1 - 6.6e-12 45.6 0.2 2.1e-11 44.0 0.2 1.9 1 0 0 1 1 1 1 PCI domain Syntaxin_2 PF14523.1 CAR24102.1 - 0.0057 16.6 0.7 0.013 15.5 0.4 1.7 1 1 0 1 1 1 1 Syntaxin-like protein Syntaxin PF00804.20 CAR24102.1 - 0.007 16.5 2.0 0.021 14.9 1.3 1.9 1 1 0 1 1 1 1 Syntaxin zf-C4pol PF14260.1 CAR24102.1 - 0.1 12.5 0.8 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DivIC PF04977.10 CAR24102.1 - 0.14 11.6 2.8 0.26 10.8 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 CAR24102.1 - 0.17 12.2 3.2 0.5 10.7 0.3 2.5 2 0 0 2 2 2 0 SlyX Muted PF14942.1 CAR24102.1 - 0.32 10.8 3.5 0.2 11.5 0.6 1.9 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein V-ATPase_H_N PF03224.9 CAR24103.1 - 1.9e-61 207.8 11.0 1.9e-61 207.8 4.8 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CAR24103.1 - 2.8e-40 136.9 1.6 8e-40 135.4 0.2 2.3 1 1 1 2 2 2 1 V-ATPase subunit H HEAT PF02985.17 CAR24103.1 - 0.07 13.2 0.0 0.5 10.5 0.0 2.6 1 0 0 1 1 1 0 HEAT repeat DUF3493 PF11998.3 CAR24103.1 - 0.13 12.2 0.4 0.8 9.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3493) HEAT_2 PF13646.1 CAR24103.1 - 0.13 12.5 2.5 15 5.9 0.0 3.7 3 1 0 3 3 3 0 HEAT repeats Gln-synt_C PF00120.19 CAR24104.1 - 1.4e-61 207.9 0.0 1.7e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CAR24104.1 - 4.7e-21 74.1 0.0 7.9e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain BCSC_C PF05420.6 CAR24104.1 - 0.036 13.2 0.2 0.052 12.6 0.2 1.2 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) Hydrolase_6 PF13344.1 CAR24105.1 - 4.1e-23 81.1 0.0 9.4e-23 80.0 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR24105.1 - 2.9e-12 46.1 0.0 7.2e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Aha1_N PF09229.6 CAR24106.1 - 4.8e-39 133.3 0.8 2e-38 131.3 0.0 2.2 3 0 0 3 3 3 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CAR24106.1 - 6.8e-13 48.8 0.1 1.1e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Fungal_trans_2 PF11951.3 CAR24107.1 - 1.2e-12 47.1 0.5 1.2e-12 47.1 0.4 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR24107.1 - 4.9e-09 35.9 12.6 8e-09 35.2 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Folate_carrier PF01770.13 CAR24107.1 - 0.42 9.0 1.5 0.72 8.2 1.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier DUF1840 PF08895.6 CAR24107.1 - 4.7 7.2 11.5 10 6.1 2.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Cpn60_TCP1 PF00118.19 CAR24108.1 - 7.2e-143 476.7 13.2 8.4e-143 476.4 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PQ-loop PF04193.9 CAR24109.1 - 2.8e-23 81.2 9.2 1.9e-19 68.9 1.1 2.5 2 0 0 2 2 2 2 PQ loop repeat Mem_trans PF03547.13 CAR24109.1 - 0.0091 14.3 1.2 0.0098 14.2 0.0 1.7 2 0 0 2 2 2 1 Membrane transport protein ABC2_membrane_5 PF13346.1 CAR24109.1 - 2.7 7.2 17.5 0.23 10.7 3.6 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein Ras PF00071.17 CAR24110.1 - 2.3e-51 173.3 0.0 2.7e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR24110.1 - 1.3e-13 51.4 0.0 1.7e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR24110.1 - 2.1e-07 30.3 0.0 2.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family W2 PF02020.13 CAR24111.1 - 6.2e-14 51.7 7.6 6.2e-14 51.7 5.3 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 CAR24111.1 - 6.2e-11 41.2 14.9 0.001 18.4 0.1 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CAR24111.1 - 2.2e-09 36.9 0.0 4.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 CAR24111.1 - 0.0012 18.3 15.2 0.15 11.6 2.7 3.7 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 CAR24111.1 - 0.0019 18.3 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 CAR24111.1 - 0.016 13.8 1.6 0.13 10.7 0.5 2.2 1 1 1 2 2 2 0 L-fucokinase CYSTM PF12734.2 CAR24112.1 - 1.2e-07 31.7 60.9 0.004 17.1 33.6 3.9 1 1 1 2 2 2 2 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 CAR24112.1 - 0.16 12.0 27.2 0.23 11.5 18.8 1.2 1 0 0 1 1 1 0 Proline-rich Extensin_2 PF04554.8 CAR24112.1 - 8.3 6.3 20.9 33 4.4 14.5 1.8 1 1 0 1 1 1 0 Extensin-like region PIP5K PF01504.13 CAR24113.1 - 2.1e-85 285.8 1.7 2.9e-85 285.3 1.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase E1-E2_ATPase PF00122.15 CAR24114.1 - 4.3e-67 225.5 6.9 8.9e-67 224.4 4.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAR24114.1 - 4.1e-32 111.1 2.3 4.1e-32 111.1 1.6 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAR24114.1 - 9.6e-30 104.5 0.1 1e-24 88.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR24114.1 - 4.5e-21 74.6 0.0 9.2e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CAR24114.1 - 9.8e-16 58.4 0.0 2e-15 57.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CAR24114.1 - 6.4e-13 47.9 0.0 2e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR24114.1 - 0.00063 19.4 0.6 0.0068 16.0 0.8 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aminotran_5 PF00266.14 CAR24115.1 - 4.8e-13 48.5 0.0 1.1e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V RICTOR_M PF14666.1 CAR24115.1 - 0.17 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Zn_clus PF00172.13 CAR24116.1 - 4.9e-09 35.9 8.4 8.3e-09 35.2 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EST1_DNA_bind PF10373.4 CAR24117.1 - 5.9e-48 163.4 1.1 5.9e-48 163.4 0.7 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CAR24117.1 - 5.7e-26 91.0 3.1 1.7e-25 89.4 2.1 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 Topoisom_bac PF01131.15 CAR24118.1 - 1.2e-94 317.3 0.0 1.5e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CAR24118.1 - 2.6e-19 69.0 0.0 6.6e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Cation_efflux PF01545.16 CAR24119.1 - 2.3e-52 177.8 7.1 2.3e-52 177.8 4.9 2.3 2 1 0 2 2 2 1 Cation efflux family SelP_N PF04592.9 CAR24119.1 - 4.7 6.5 26.9 0.39 10.0 11.5 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Transp_cyt_pur PF02133.10 CAR24120.1 - 1.4e-74 251.2 38.6 2e-74 250.7 26.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Coq4 PF05019.8 CAR24121.1 - 2.5e-97 324.1 0.0 3.1e-97 323.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rogdi_lz PF10259.4 CAR24122.1 - 3.1e-69 233.1 1.5 3.5e-69 232.9 1.1 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DUF4497 PF14924.1 CAR24122.1 - 0.051 13.8 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) DASH_Spc19 PF08287.6 CAR24123.1 - 6.1e-39 133.0 12.2 6.9e-39 132.9 8.5 1.0 1 0 0 1 1 1 1 Spc19 Sds3 PF08598.6 CAR24123.1 - 0.0088 15.5 1.3 0.017 14.6 0.9 1.5 1 1 0 1 1 1 1 Sds3-like RNA_pol_Rpb5_C PF01191.14 CAR24123.1 - 0.023 14.2 1.9 0.037 13.6 0.1 2.0 2 1 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Glutaredoxin2_C PF04399.8 CAR24123.1 - 0.14 11.7 1.5 0.22 11.1 0.2 1.8 1 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain H-kinase_dim PF02895.9 CAR24123.1 - 0.56 10.5 8.0 2.1 8.7 0.5 2.9 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain BLOC1_2 PF10046.4 CAR24123.1 - 1.5 8.9 6.0 25 5.0 0.0 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.5 CAR24123.1 - 1.8 8.5 8.5 1.2 9.1 0.4 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad2 Baculo_PEP_C PF04513.7 CAR24123.1 - 4 7.2 8.6 8 6.2 1.9 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CAR24123.1 - 7.4 5.6 10.4 4.1 6.4 2.8 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein FHA PF00498.21 CAR24124.1 - 2.3e-17 62.8 0.8 1.5e-16 60.2 0.2 2.5 1 1 1 2 2 2 1 FHA domain Exonuc_VII_L PF02601.10 CAR24124.1 - 8.1 5.5 14.6 12 4.9 10.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BPL_LplA_LipB PF03099.14 CAR24125.1 - 1.9e-17 63.4 0.0 3.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SET PF00856.23 CAR24126.1 - 4.6e-06 27.0 0.0 6.9e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 SET domain ApbA PF02558.11 CAR24127.1 - 1e-05 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CAR24127.1 - 6.9e-05 22.8 0.0 0.00021 21.2 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal HJURP_mid PF12346.3 CAR24127.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat CoaE PF01121.15 CAR24128.1 - 6.6e-59 198.3 0.0 7.7e-59 198.1 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 CAR24128.1 - 8.8e-08 33.0 0.1 1.3e-07 32.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR24128.1 - 1.5e-05 24.8 0.0 0.00028 20.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR24128.1 - 0.00014 22.1 0.2 0.00093 19.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 CAR24128.1 - 0.00019 21.3 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Cytidylate_kin2 PF13189.1 CAR24128.1 - 0.0005 20.0 0.2 0.0086 16.0 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.1 CAR24128.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 CAR24128.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IPT PF01745.11 CAR24128.1 - 0.13 11.4 0.1 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Isopentenyl transferase DEAD PF00270.24 CAR24130.1 - 5e-41 139.9 0.1 1.6e-40 138.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR24130.1 - 1e-16 60.5 0.0 2.7e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR24130.1 - 2e-06 27.7 0.1 3.7e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PI3Ka PF00613.15 CAR24131.1 - 1.4e-67 226.4 0.8 2.3e-67 225.7 0.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CAR24131.1 - 1.5e-46 158.7 0.0 1e-45 156.0 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CAR24131.1 - 1.1e-19 70.5 0.2 5.4e-19 68.3 0.1 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF221 PF02714.10 CAR24132.1 - 1.1e-96 323.5 19.8 1.7e-96 322.8 13.7 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CAR24132.1 - 5.1e-38 130.0 0.4 5.1e-38 130.0 0.3 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CAR24132.1 - 4.5e-17 62.3 0.0 7.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) YMF19 PF02326.10 CAR24132.1 - 3.1 8.4 8.5 16 6.1 0.4 3.8 2 1 1 3 3 3 0 Plant ATP synthase F0 Arv1 PF04161.8 CAR24133.1 - 4.8e-76 255.2 15.3 4.8e-76 255.2 10.6 1.3 2 0 0 2 2 2 1 Arv1-like family zf-CCCH PF00642.19 CAR24134.1 - 9.5e-07 28.3 3.2 1.9e-06 27.4 2.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ATP_bind_1 PF03029.12 CAR24135.1 - 2.9e-84 282.3 0.0 3.3e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CAR24135.1 - 3.9e-05 23.2 0.0 7.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 CAR24135.1 - 0.00027 21.7 0.1 0.00073 20.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CAR24135.1 - 0.0004 19.2 0.0 0.00083 18.2 0.0 1.4 2 0 0 2 2 1 1 ArgK protein MMR_HSR1 PF01926.18 CAR24135.1 - 0.00065 19.6 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.9 CAR24135.1 - 0.0021 17.1 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain GTP_EFTU PF00009.22 CAR24135.1 - 0.005 16.3 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CAR24135.1 - 0.0062 16.8 0.0 0.02 15.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter DUF87 PF01935.12 CAR24135.1 - 0.0062 16.3 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 CAR24135.1 - 0.0067 16.5 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 1 1 RNA helicase MobB PF03205.9 CAR24135.1 - 0.0079 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CAR24135.1 - 0.0081 15.7 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 CAR24135.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 CAR24135.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 CAR24135.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CAR24135.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CAR24135.1 - 0.019 14.9 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 CAR24135.1 - 0.021 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CAR24135.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 CAR24135.1 - 0.038 13.1 0.0 0.083 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 CAR24135.1 - 0.041 13.3 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 CAR24135.1 - 0.041 14.0 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CAR24135.1 - 0.047 13.4 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CAR24135.1 - 0.052 13.2 0.2 0.13 11.9 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.1 CAR24135.1 - 0.056 13.7 0.1 0.31 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAR24135.1 - 0.06 12.9 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CAR24135.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.13 CAR24135.1 - 0.089 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.11 CAR24135.1 - 0.095 11.7 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_14 PF13173.1 CAR24135.1 - 0.1 12.5 0.0 0.38 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CAR24135.1 - 0.1 12.2 0.0 0.72 9.5 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase ADK PF00406.17 CAR24135.1 - 0.11 12.4 0.1 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase Thymidylate_kin PF02223.12 CAR24135.1 - 0.11 11.8 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.13 CAR24135.1 - 0.13 11.7 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PPV_E1_C PF00519.12 CAR24135.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_5 PF07728.9 CAR24135.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) SIR2 PF02146.12 CAR24136.1 - 7e-28 97.5 0.0 1.1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF3039 PF11238.3 CAR24136.1 - 0.26 10.7 1.4 6 6.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) TIP49 PF06068.8 CAR24137.1 - 1.5e-187 623.1 0.4 1.8e-187 622.9 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CAR24137.1 - 1.4e-08 35.0 0.2 5.8e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR24137.1 - 8.7e-08 31.4 2.5 0.00017 20.6 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CAR24137.1 - 0.00096 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR24137.1 - 0.0016 18.4 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CAR24137.1 - 0.0065 16.3 0.1 1.2 9.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CAR24137.1 - 0.0078 15.3 0.1 0.021 13.9 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 CAR24137.1 - 0.018 14.7 1.0 0.038 13.7 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain DnaB_C PF03796.10 CAR24137.1 - 0.02 13.8 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 CAR24137.1 - 0.021 13.9 0.1 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.7 CAR24137.1 - 0.036 13.6 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.9 CAR24137.1 - 0.037 13.7 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CAR24137.1 - 0.07 12.6 0.0 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 CAR24137.1 - 0.12 11.7 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Sec1 PF00995.18 CAR24138.1 - 2.9e-141 471.9 4.7 3.3e-141 471.7 3.3 1.0 1 0 0 1 1 1 1 Sec1 family Cpn60_TCP1 PF00118.19 CAR24139.1 - 2e-145 485.1 1.4 2.2e-145 484.9 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.19 CAR24140.1 - 1.5e-46 158.5 0.1 1.9e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 dCMP_cyt_deam_1 PF00383.17 CAR24141.1 - 1.1e-17 63.5 0.9 1.3e-17 63.2 0.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CAR24141.1 - 1e-10 41.6 0.2 4.3e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CAR24141.1 - 0.018 14.4 2.6 0.56 9.5 0.2 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Ribosomal_S14 PF00253.16 CAR24141.1 - 0.12 11.7 0.9 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e NOA36 PF06524.7 CAR24142.1 - 0.11 11.7 2.8 0.23 10.7 2.0 1.4 1 0 0 1 1 1 0 NOA36 protein zf-DHHC PF01529.15 CAR24143.1 - 1.8e-37 128.4 8.4 1.8e-37 128.4 5.8 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase PRELI PF04707.9 CAR24144.1 - 7.1e-56 188.1 0.4 9.4e-56 187.7 0.3 1.2 1 0 0 1 1 1 1 PRELI-like family ubiquitin PF00240.18 CAR24146.1 - 1.3e-34 117.4 0.9 2.6e-34 116.4 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 CAR24146.1 - 7.4e-25 86.5 2.7 1.4e-24 85.6 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CAR24146.1 - 9.8e-20 70.0 0.7 9.8e-20 70.0 0.5 1.8 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR24146.1 - 9.3e-06 25.8 0.2 3.8e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CAR24146.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CAR24146.1 - 0.00095 19.0 0.6 0.0025 17.6 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CAR24146.1 - 0.0032 17.6 0.3 0.0042 17.2 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DZR PF12773.2 CAR24146.1 - 0.0062 16.3 0.3 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 CAR24146.1 - 0.046 12.9 5.5 0.1 11.8 3.8 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 CAR24146.1 - 0.055 13.2 0.8 0.094 12.5 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF2870 PF11069.3 CAR24146.1 - 0.067 13.2 0.3 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) GCC2_GCC3 PF07699.8 CAR24146.1 - 0.095 12.3 1.7 0.19 11.3 1.2 1.4 1 0 0 1 1 1 0 GCC2 and GCC3 Plexin_cytopl PF08337.7 CAR24146.1 - 0.16 10.2 2.0 4.7 5.4 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain TF_Zn_Ribbon PF08271.7 CAR24146.1 - 0.19 11.0 2.1 0.75 9.1 1.6 1.9 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 CAR24146.1 - 0.77 9.3 4.8 0.8 9.2 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain DUF35_N PF12172.3 CAR24146.1 - 0.93 9.4 3.0 6.8 6.7 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-H2C2_2 PF13465.1 CAR24146.1 - 1.7 9.0 6.4 15 6.0 0.7 2.6 2 1 0 2 2 2 0 Zinc-finger double domain Nudix_N_2 PF14803.1 CAR24146.1 - 2.1 8.0 7.0 25 4.6 4.0 2.4 1 1 1 2 2 2 0 Nudix N-terminal Phosducin PF02114.11 CAR24147.1 - 1.3e-11 43.7 0.3 1.5e-11 43.4 0.2 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 CAR24147.1 - 3.4e-06 26.6 0.1 5.4e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin NuiA PF07924.6 CAR24147.1 - 0.066 13.1 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Mit_KHE1 PF10173.4 CAR24147.1 - 0.081 12.7 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Sec10 PF07393.6 CAR24148.1 - 2.6e-188 627.5 20.3 3.3e-188 627.2 14.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 PEPcase_2 PF14010.1 CAR24148.1 - 0.00059 18.2 2.6 0.00077 17.8 0.5 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase COG2 PF06148.6 CAR24148.1 - 0.7 9.7 7.2 0.14 12.0 0.2 3.4 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Metallophos PF00149.23 CAR24149.1 - 8e-14 51.4 1.3 1.4e-13 50.6 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR24149.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SAS4 PF15460.1 CAR24150.1 - 1.3e-30 105.2 2.7 2.9e-30 104.1 1.9 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 ORC6 PF05460.8 CAR24150.1 - 1.6 7.7 11.8 1.1 8.3 3.6 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Nipped-B_C PF12830.2 CAR24151.1 - 4.5e-36 124.2 3.0 1.3e-35 122.7 0.3 3.0 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 CAR24151.1 - 6.7e-15 54.6 0.3 1.8e-11 43.7 1.1 3.8 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 CAR24151.1 - 0.07 13.4 0.1 1.4 9.2 0.0 3.2 2 1 1 3 3 3 0 HEAT repeats PseudoU_synth_2 PF00849.17 CAR24152.1 - 7.1e-21 74.7 0.5 9.1e-19 67.8 0.4 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase PXA PF02194.10 CAR24153.1 - 4.2e-09 36.2 0.2 7.5e-08 32.1 0.0 2.4 1 1 1 2 2 2 1 PXA domain Nexin_C PF08628.7 CAR24153.1 - 0.0019 18.2 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 Sorting nexin C terminal CybS PF05328.7 CAR24155.1 - 4.5e-50 168.7 0.0 5.7e-50 168.3 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 CAR24155.1 - 0.00063 19.5 0.3 0.11 12.3 0.2 2.2 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_M16 PF00675.15 CAR24156.1 - 2.5e-51 173.3 0.0 4.6e-51 172.4 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR24156.1 - 2.6e-37 128.2 0.0 1.1e-35 122.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Ada3 PF10198.4 CAR24157.1 - 1.9e-46 157.0 4.6 4.8e-46 155.7 3.2 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 MRP-S28 PF10213.4 CAR24158.1 - 1.7e-51 173.6 2.9 1.7e-51 173.6 2.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF4158 PF13700.1 CAR24158.1 - 0.04 13.3 1.9 0.089 12.2 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) HMG_box PF00505.14 CAR24159.1 - 5.2e-10 39.4 2.4 5.2e-10 39.4 1.7 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR24159.1 - 5.8e-08 32.9 1.2 5.8e-08 32.9 0.8 1.9 2 0 0 2 2 2 1 HMG-box domain ERAP1_C PF11838.3 CAR24159.1 - 0.0033 16.7 0.1 0.0047 16.2 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain RNase_PH PF01138.16 CAR24159.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 DUF3086 PF11285.3 CAR24159.1 - 0.073 11.8 0.3 0.14 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) MFS_1 PF07690.11 CAR24160.1 - 3e-33 115.0 27.5 6.5e-33 113.9 19.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 CAR24160.1 - 0.0007 19.5 2.3 0.0016 18.4 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) FixQ PF05545.6 CAR24160.1 - 0.01 15.4 2.6 0.032 13.8 0.0 2.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Zip PF02535.17 CAR24161.1 - 6.2e-55 186.4 11.2 7.2e-55 186.2 7.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1422 PF07226.6 CAR24161.1 - 2.5 7.8 7.0 0.29 10.8 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) IPK PF03770.11 CAR24162.1 - 2.8e-55 187.0 0.1 3.8e-55 186.5 0.1 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase GTP_EFTU PF00009.22 CAR24163.1 - 1.6e-47 161.4 0.1 9.2e-47 158.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAR24163.1 - 6.4e-25 87.2 0.6 1.6e-24 85.9 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAR24163.1 - 1.8e-05 24.7 0.3 4.8e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR24163.1 - 0.0001 22.1 0.0 0.00035 20.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase CDC27 PF09507.5 CAR24163.1 - 0.033 13.4 24.2 0.05 12.8 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 G-alpha PF00503.15 CAR24163.1 - 0.5 9.0 6.9 1.6 7.2 4.8 1.8 1 1 0 1 1 1 0 G-protein alpha subunit eIF-3c_N PF05470.7 CAR24163.1 - 3 5.7 9.7 4.8 5.1 6.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mitofilin PF09731.4 CAR24163.1 - 4.1 5.9 19.5 6.1 5.3 13.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HSP20 PF00011.16 CAR24164.1 - 2.1e-10 40.3 0.4 4.7e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Hsp20/alpha crystallin family GTP_CH_N PF12471.3 CAR24165.1 - 1e-84 283.0 0.0 1.6e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 CAR24165.1 - 1.2e-17 63.6 0.0 1.8e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Sec7 PF01369.15 CAR24166.1 - 7.8e-65 218.1 0.3 3.3e-64 216.0 0.2 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CAR24166.1 - 1.7e-55 187.0 3.1 1.7e-55 187.0 2.2 4.0 6 0 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CAR24166.1 - 2.4e-28 97.4 5.2 7.4e-28 95.9 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Chorismate_synt PF01264.16 CAR24167.1 - 4.2e-133 443.1 0.0 4.8e-133 442.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SH3_2 PF07653.12 CAR24168.1 - 1.9e-07 30.4 0.1 4.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CAR24168.1 - 5e-06 26.0 0.1 1.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR24168.1 - 8.2e-06 25.1 0.1 2.3e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 SH3 domain Transglut_core PF01841.14 CAR24168.1 - 0.00071 19.7 0.0 0.0048 17.0 0.0 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily Nup84_Nup100 PF04121.8 CAR24169.1 - 2.6e-189 630.2 8.6 3e-189 630.0 5.9 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 EDR1 PF14381.1 CAR24169.1 - 0.066 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 GTP-bdg_N PF13167.1 CAR24169.1 - 0.6 10.2 3.6 2.4 8.3 0.0 2.9 2 1 1 3 3 3 0 GTP-binding GTPase N-terminal Ribosomal_L6 PF00347.18 CAR24170.1 - 1.3e-30 105.6 11.3 1.1e-15 57.9 3.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 CAR24170.1 - 0.0046 16.1 0.9 0.016 14.4 0.0 2.2 3 0 0 3 3 3 1 Transcriptional Coactivator p15 (PC4) DUF2067 PF09840.4 CAR24170.1 - 0.075 12.5 0.5 0.14 11.6 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) DUF1762 PF08574.5 CAR24171.1 - 9.4e-19 67.6 13.9 9.4e-19 67.6 9.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) PX PF00787.19 CAR24172.1 - 1e-23 83.2 0.1 3.7e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 PX domain FlaC_arch PF05377.6 CAR24172.1 - 0.15 11.9 3.4 0.72 9.8 1.0 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CAR24172.1 - 1.2 8.6 12.5 2.6 7.6 0.2 2.7 2 1 0 2 2 2 0 IncA protein DUF342 PF03961.8 CAR24172.1 - 6.3 5.0 10.2 0.75 8.1 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF342) SpoU_methylase PF00588.14 CAR24173.1 - 1.3e-25 89.9 0.0 3.1e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family RNase_PH PF01138.16 CAR24174.1 - 5.2e-15 55.9 0.0 7.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 MOZART1 PF12554.3 CAR24174.1 - 0.023 14.1 0.5 3.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated RNase_PH_C PF03725.10 CAR24174.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 EMP24_GP25L PF01105.19 CAR24175.1 - 2.9e-08 33.6 0.0 4.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cortex-I_coil PF09304.5 CAR24176.1 - 0.0025 17.8 1.3 0.0041 17.1 0.7 1.4 1 1 0 1 1 1 1 Cortexillin I, coiled coil Med9 PF07544.8 CAR24176.1 - 0.078 12.7 0.5 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 RINT1_TIP1 PF04437.8 CAR24177.1 - 5.5e-69 233.0 25.9 3.9e-68 230.1 18.0 2.0 1 1 0 1 1 1 1 RINT-1 / TIP-1 family DUF676 PF05057.9 CAR24178.1 - 2.1e-58 197.1 0.0 3.3e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CAR24178.1 - 0.0014 18.2 0.0 0.0039 16.8 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CAR24178.1 - 0.0039 16.8 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 CAR24178.1 - 0.013 14.5 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RF-1 PF00472.15 CAR24179.1 - 3.9e-39 132.9 4.4 8.2e-39 131.9 3.1 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CAR24179.1 - 7e-33 112.7 0.5 2.4e-32 111.0 0.0 2.1 3 0 0 3 3 3 1 PCRF domain NAPRTase PF04095.11 CAR24179.1 - 0.053 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Cnd1_N PF12922.2 CAR24179.1 - 1.7 8.2 4.6 0.28 10.8 0.2 1.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term Pkinase PF00069.20 CAR24180.1 - 3.3e-68 229.6 0.0 3.9e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24180.1 - 6.1e-29 100.8 0.0 7.8e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR24180.1 - 0.00054 19.0 0.0 0.00079 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR24180.1 - 0.0095 15.6 0.1 0.02 14.6 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DAO PF01266.19 CAR24181.1 - 1.6e-46 158.8 0.0 1.8e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAR24181.1 - 5.5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CAR24181.1 - 2.5e-05 24.2 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAR24181.1 - 2.7e-05 23.2 0.1 0.0015 17.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CAR24181.1 - 3.4e-05 24.0 0.0 0.0015 18.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CAR24181.1 - 0.00014 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.22 CAR24181.1 - 0.00039 20.7 0.1 0.0026 18.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAR24181.1 - 0.0025 16.3 0.0 0.021 13.3 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CAR24181.1 - 0.0043 16.1 0.1 0.0093 15.0 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 CAR24181.1 - 0.0062 15.5 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CAR24181.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 CAR24181.1 - 0.058 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 GMC oxidoreductase UDPG_MGDP_dh_N PF03721.9 CAR24181.1 - 0.085 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 CAR24181.1 - 0.15 11.0 0.0 0.31 10.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain TPR_11 PF13414.1 CAR24182.1 - 6.4e-09 35.3 0.4 0.00022 20.8 0.1 4.4 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.1 CAR24182.1 - 2.1e-06 27.5 0.2 0.0011 18.8 0.0 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR24182.1 - 4.3e-05 23.0 1.6 0.15 12.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR24182.1 - 0.00077 19.0 3.3 3.9 7.4 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR24182.1 - 0.0011 19.4 0.0 2.1 9.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAR24182.1 - 0.0013 18.2 1.7 0.34 10.5 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR24182.1 - 0.0034 17.7 0.2 0.43 10.9 0.0 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR24182.1 - 0.0046 16.6 0.1 0.84 9.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR24182.1 - 0.11 13.1 0.2 1.2 9.8 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 CAR24182.1 - 0.79 10.4 3.3 1.2e+02 3.5 0.0 4.3 4 0 0 4 4 4 0 Sel1 repeat Glyco_transf_22 PF03901.12 CAR24183.1 - 2e-96 323.5 31.8 2.4e-96 323.2 22.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HECT PF00632.20 CAR24184.1 - 2.2e-82 276.7 1.4 4.9e-82 275.6 0.4 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CAR24185.1 - 2.9e-13 49.9 0.2 6.6e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 SPRY domain Homeobox PF00046.24 CAR24186.1 - 2.2e-19 68.7 4.0 4e-19 67.9 2.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CAR24186.1 - 0.004 16.8 0.7 0.01 15.5 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Aldedh PF00171.17 CAR24187.1 - 2.5e-174 579.9 0.0 2.9e-174 579.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CAR24187.1 - 1.8e-06 26.9 0.0 2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1330 PF07045.6 CAR24187.1 - 0.11 12.3 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Aldedh PF00171.17 CAR24188.1 - 1.5e-169 564.2 0.7 1.7e-169 564.0 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.13 CAR24189.1 - 4.4e-06 26.4 10.4 9.7e-06 25.4 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lysis_S PF04971.7 CAR24189.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Lysis protein S DNA_mis_repair PF01119.14 CAR24190.1 - 9.4e-30 102.5 0.0 1.9e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CAR24190.1 - 1.1e-13 50.9 0.1 2.4e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CAR24190.1 - 3.8e-10 39.4 0.0 8.3e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nse4_C PF08743.5 CAR24191.1 - 2.6e-24 85.0 0.0 9.7e-24 83.2 0.0 2.1 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CAR24191.1 - 5.2e-06 26.2 0.7 1.2e-05 25.0 0.5 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF2113 PF09886.4 CAR24191.1 - 0.042 12.9 0.0 0.081 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) Peptidase_M22 PF00814.20 CAR24192.1 - 4.4e-71 239.5 0.0 5.4e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 CAR24192.1 - 0.034 13.2 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Carbamoyltransferase Mito_carr PF00153.22 CAR24193.1 - 1.6e-63 210.4 0.4 1.4e-22 79.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LNS2 PF08235.8 CAR24194.1 - 9.3e-71 236.4 0.0 1.4e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CAR24194.1 - 1.1e-43 147.3 0.0 2e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 CAR24194.1 - 0.00014 21.7 0.3 0.00014 21.7 0.2 2.8 2 1 0 2 2 2 1 Drug resistance and apoptosis regulator Hydrolase_6 PF13344.1 CAR24194.1 - 0.048 13.5 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LisH PF08513.6 CAR24195.1 - 0.0029 17.3 1.3 0.0073 16.0 0.9 1.8 1 0 0 1 1 1 1 LisH Vezatin PF12632.2 CAR24196.1 - 4.8e-46 156.8 1.9 9e-46 155.9 1.3 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes UDPGP PF01704.13 CAR24197.1 - 5.4e-47 160.2 0.0 7e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CAR24197.1 - 0.0044 17.1 0.0 0.0089 16.1 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hydrolase PF00702.21 CAR24198.1 - 4.7e-19 69.6 0.0 7e-18 65.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CAR24198.1 - 5.6e-19 68.0 0.0 2.4e-18 66.0 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CAR24198.1 - 6.8e-14 52.4 0.4 1.7e-12 47.9 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR24198.1 - 5.6e-12 45.4 0.0 3.5e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CAR24198.1 - 0.0032 17.0 2.8 0.01 15.4 0.1 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.26 CAR24199.1 - 6.6e-27 93.0 1.6 1.1e-26 92.3 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 CAR24199.1 - 0.046 13.1 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein DNA_pol_B PF00136.16 CAR24200.1 - 3.7e-137 457.8 1.7 5e-137 457.4 1.2 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CAR24200.1 - 7.7e-86 287.9 0.0 1.3e-85 287.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CAR24200.1 - 1.2e-23 82.8 4.4 2.5e-23 81.8 3.0 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CAR24200.1 - 0.00016 20.4 4.8 0.0015 17.2 0.5 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 CAR24200.1 - 0.00049 19.6 0.0 0.00099 18.6 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CAR24200.1 - 0.00087 19.1 0.4 0.0043 16.8 0.3 2.1 1 1 0 1 1 1 1 RNase_H superfamily Pkinase PF00069.20 CAR24201.1 - 3.6e-71 239.3 0.0 4.5e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24201.1 - 1.7e-36 125.6 0.0 2.3e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CAR24201.1 - 2.5e-08 33.8 0.4 5.4e-08 32.8 0.3 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 CAR24201.1 - 0.0002 20.4 0.7 1.1 8.1 0.1 3.7 3 1 1 4 4 4 2 Kinase-like Kdo PF06293.9 CAR24201.1 - 0.0024 16.9 0.1 0.0035 16.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CAR24201.1 - 0.068 12.5 1.2 0.21 10.9 0.8 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 CAR24201.1 - 0.074 12.3 1.5 0.44 9.8 1.1 1.9 1 1 0 1 1 1 0 RIO1 family ATG16 PF08614.6 CAR24203.1 - 1.5e-27 96.6 17.8 1.2e-24 87.2 9.8 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.1 CAR24203.1 - 0.0013 18.0 10.7 0.01 15.0 1.6 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Fez1 PF06818.10 CAR24203.1 - 0.0055 16.7 4.6 0.0063 16.5 3.2 1.2 1 0 0 1 1 1 1 Fez1 Phage_GP20 PF06810.6 CAR24203.1 - 0.01 15.2 11.9 0.016 14.6 8.2 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 CAR24203.1 - 0.011 15.3 9.4 0.013 15.0 6.5 1.2 1 0 0 1 1 1 0 IncA protein Toxin_trans PF07952.7 CAR24203.1 - 0.021 13.7 1.8 0.025 13.5 1.0 1.3 1 1 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Tho2 PF11262.3 CAR24203.1 - 0.028 13.4 4.0 0.031 13.3 2.8 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.4 CAR24203.1 - 0.041 12.8 8.6 0.046 12.6 6.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MerR-DNA-bind PF09278.6 CAR24203.1 - 0.042 14.2 1.0 9.9 6.6 0.1 2.3 2 0 0 2 2 2 0 MerR, DNA binding TMF_TATA_bd PF12325.3 CAR24203.1 - 0.051 13.3 8.4 0.05 13.3 5.3 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Macoilin PF09726.4 CAR24203.1 - 0.063 11.5 5.4 0.064 11.5 3.7 1.0 1 0 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 CAR24203.1 - 0.067 12.7 9.0 0.089 12.3 6.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 CAR24203.1 - 0.083 12.7 10.7 0.12 12.1 7.4 1.3 1 0 0 1 1 1 0 Tropomyosin like YojJ PF10372.4 CAR24203.1 - 0.1 12.4 0.9 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus ADIP PF11559.3 CAR24203.1 - 0.12 12.3 9.6 0.16 11.8 6.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 CAR24203.1 - 0.15 11.7 4.3 0.11 12.3 1.7 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1423 PF07227.6 CAR24203.1 - 0.22 10.1 4.9 0.25 9.9 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) LRS4 PF10422.4 CAR24203.1 - 0.3 10.4 8.6 0.26 10.6 5.4 1.5 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DUF848 PF05852.6 CAR24203.1 - 0.41 10.4 8.1 0.72 9.6 5.6 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4140 PF13600.1 CAR24203.1 - 0.45 10.9 7.1 0.36 11.2 1.2 2.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 CAR24203.1 - 0.58 10.0 14.5 0.13 12.0 2.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.4 CAR24203.1 - 0.58 9.9 10.0 0.23 11.2 2.6 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 CAR24203.1 - 0.6 10.1 9.2 2.2 8.3 6.4 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CAR24203.1 - 0.6 9.0 9.7 0.68 8.9 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 CAR24203.1 - 0.87 9.9 8.7 0.89 9.9 5.2 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF972) Activator-TraM PF11657.3 CAR24203.1 - 0.99 8.8 5.6 8.3 5.8 0.2 2.2 1 1 1 2 2 2 0 Transcriptional activator TraM DUF342 PF03961.8 CAR24203.1 - 1 7.7 6.4 1.1 7.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 CAR24203.1 - 1.2 8.7 11.9 0.24 10.9 1.1 2.7 1 1 2 3 3 3 0 Septum formation initiator GrpE PF01025.14 CAR24203.1 - 1.2 8.6 10.1 51 3.3 6.9 2.1 1 1 0 1 1 1 0 GrpE Cortex-I_coil PF09304.5 CAR24203.1 - 1.3 9.0 13.5 0.38 10.8 7.4 1.6 2 1 0 2 2 1 0 Cortexillin I, coiled coil Bap31 PF05529.7 CAR24203.1 - 1.5 8.2 6.5 2 7.8 3.7 1.8 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Vfa1 PF08432.5 CAR24203.1 - 4.7 7.2 8.0 2.1 8.3 1.2 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 bZIP_1 PF00170.16 CAR24203.1 - 6.2 6.8 8.4 3 7.8 1.5 2.4 1 1 1 2 2 2 0 bZIP transcription factor ArsA_ATPase PF02374.10 CAR24204.1 - 3.8e-114 380.8 0.0 4.4e-114 380.6 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CAR24204.1 - 2.2e-13 50.0 0.0 3.2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CAR24204.1 - 0.00049 20.0 0.1 0.005 16.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CAR24204.1 - 0.00051 19.3 0.0 0.0012 18.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CAR24204.1 - 0.026 13.9 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CAR24204.1 - 0.078 12.3 0.0 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CAR24204.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FlxA PF14282.1 CAR24205.1 - 0.0086 16.0 13.7 0.0086 16.0 9.5 4.2 2 1 2 4 4 4 1 FlxA-like protein DUF848 PF05852.6 CAR24205.1 - 0.015 15.1 10.2 0.015 15.1 7.1 3.3 1 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) REF PF05755.7 CAR24205.1 - 0.028 14.1 0.8 0.028 14.1 0.6 2.2 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Ribosomal_S8 PF00410.14 CAR24206.1 - 4.2e-20 71.8 0.0 5.4e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 zf-C2H2_jaz PF12171.3 CAR24208.1 - 7e-06 26.0 1.5 1.4e-05 25.0 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR24208.1 - 1.1e-05 25.4 1.4 2e-05 24.6 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 CAR24208.1 - 0.01 15.4 0.6 0.024 14.3 0.4 1.5 1 0 0 1 1 1 0 DBF zinc finger Peptidase_S41 PF03572.13 CAR24208.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S41 zf-C2H2_2 PF12756.2 CAR24208.1 - 0.075 13.1 0.2 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF2066 PF09839.4 CAR24208.1 - 0.11 11.5 0.0 0.37 9.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) zf-C2H2 PF00096.21 CAR24208.1 - 0.35 11.3 2.0 0.69 10.3 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type PNK3P PF08645.6 CAR24209.1 - 1.5e-39 135.0 0.1 3.2e-39 133.9 0.0 1.5 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase PCI PF01399.22 CAR24210.1 - 4.6e-17 62.2 0.0 2e-16 60.1 0.0 2.2 1 0 0 1 1 1 1 PCI domain TPR_16 PF13432.1 CAR24210.1 - 0.00047 20.7 2.1 0.14 12.8 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR24210.1 - 0.0012 18.6 6.3 0.066 13.1 1.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR24210.1 - 0.01 16.1 5.9 6.4 7.1 0.3 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CAR24210.1 - 0.013 15.6 1.1 0.013 15.6 0.7 4.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 CAR24210.1 - 0.083 12.9 3.7 0.42 10.6 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Rapamycin_bind PF08771.6 CAR24210.1 - 0.15 12.2 2.9 18 5.4 0.0 3.9 3 1 0 3 3 3 0 Rapamycin binding domain DDRGK PF09756.4 CAR24210.1 - 0.32 10.3 0.1 0.32 10.3 0.0 3.0 3 1 1 4 4 4 0 DDRGK domain TPR_21 PF09976.4 CAR24210.1 - 0.73 9.7 15.2 1.1 9.2 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAR24210.1 - 1.6 8.7 14.2 2.6 8.1 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2935 PF11155.3 CAR24210.1 - 2.2 8.4 7.9 0.39 10.8 0.3 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DFF40 PF09230.5 CAR24210.1 - 6.6 6.0 8.5 5.8 6.2 0.2 2.8 3 1 0 3 3 3 0 DNA fragmentation factor 40 kDa PMT PF02366.13 CAR24211.1 - 1.1e-77 260.7 20.2 1.1e-77 260.7 14.0 1.9 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CAR24211.1 - 5.3e-51 172.8 0.8 9.1e-51 172.0 0.6 1.4 1 0 0 1 1 1 1 MIR domain Nodulin-like PF06813.8 CAR24212.1 - 2e-13 50.2 5.7 2e-13 50.2 3.9 2.0 2 0 0 2 2 2 1 Nodulin-like MFS_1 PF07690.11 CAR24212.1 - 2.9e-13 49.2 15.2 3.4e-09 35.8 6.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.1 CAR24212.1 - 0.066 12.6 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 PgaD-like protein DUF1469 PF07332.6 CAR24212.1 - 0.29 10.8 3.0 21 4.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) CAAD PF14159.1 CAR24212.1 - 1.1 9.0 3.4 1.4 8.5 0.2 2.7 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF4131 PF13567.1 CAR24212.1 - 3.1 7.1 11.4 2.9 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SRP14 PF02290.10 CAR24213.1 - 1.8e-15 56.6 0.0 3.9e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein UBX PF00789.15 CAR24214.1 - 8.1e-14 51.4 0.0 1.7e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Prenyltrans PF00432.16 CAR24215.1 - 1.1e-33 114.4 26.6 9e-11 41.1 0.5 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CAR24215.1 - 3.3e-19 69.3 0.3 2.9e-08 34.1 0.1 3.9 1 1 3 4 4 4 3 Prenyltransferase-like RRM_1 PF00076.17 CAR24216.1 - 3.5e-19 68.1 5.6 3.9e-09 36.0 0.2 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24216.1 - 1.2e-14 54.0 0.9 1.3e-06 28.2 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24216.1 - 5.1e-06 26.2 0.7 0.073 12.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_capsid PF06112.6 CAR24216.1 - 0.015 15.3 1.0 0.015 15.3 0.7 2.6 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein UPF0561 PF10573.4 CAR24216.1 - 1.6 8.6 6.3 0.26 11.1 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 AMP-binding PF00501.23 CAR24217.1 - 1.3e-71 241.1 0.0 1.9e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CAR24217.1 - 8.1e-69 231.3 0.0 1.4e-68 230.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CAR24217.1 - 5.4e-15 55.4 0.0 1.3e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CAR24217.1 - 5.9e-14 52.0 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 CAR24217.1 - 3.9e-08 34.1 0.8 4.9e-07 30.5 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CAR24217.1 - 1.4e-07 30.5 0.0 2.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CAR24217.1 - 0.0075 15.2 0.0 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein SNF2_N PF00176.18 CAR24218.1 - 1.2e-72 244.2 0.2 1.7e-72 243.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR24218.1 - 2.9e-11 43.0 0.0 7.1e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR24218.1 - 2.1e-08 33.8 0.0 4.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 CAR24218.1 - 2.1e-07 30.5 11.0 2.1e-07 30.5 7.6 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CAR24218.1 - 2.9e-07 30.5 0.0 6.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 CAR24218.1 - 5.4e-05 22.9 9.2 5.4e-05 22.9 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CAR24218.1 - 0.00011 22.1 9.5 0.00011 22.1 6.6 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR24218.1 - 0.0022 17.8 10.0 0.0022 17.8 6.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CAR24218.1 - 0.14 12.0 2.9 0.4 10.4 2.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 CAR24218.1 - 0.4 10.1 12.3 0.078 12.4 1.1 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain TPR_1 PF00515.23 CAR24219.1 - 3.7e-47 156.0 21.8 1.5e-07 30.7 0.0 10.4 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 CAR24219.1 - 5.3e-43 144.5 23.9 3.3e-10 39.4 0.5 6.6 2 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 CAR24219.1 - 7e-42 138.0 20.8 8.9e-05 22.1 0.0 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 CAR24219.1 - 2.5e-29 99.0 21.0 0.00058 19.8 0.1 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.1 CAR24219.1 - 9.4e-29 99.1 31.1 1.5e-08 34.4 0.3 7.4 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.1 CAR24219.1 - 8e-27 90.9 15.5 0.067 13.0 0.2 9.7 7 1 2 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 CAR24219.1 - 9.6e-27 93.0 17.2 1.9e-05 25.2 0.0 6.7 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 CAR24219.1 - 1.1e-22 78.4 22.0 0.0003 21.1 0.1 10.2 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_19 PF14559.1 CAR24219.1 - 2.3e-19 69.5 17.2 1.4e-05 25.3 0.8 6.9 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 CAR24219.1 - 5.3e-18 63.3 24.1 0.00077 19.0 0.2 9.8 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 CAR24219.1 - 5.1e-15 54.8 18.1 0.57 10.7 0.0 9.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 CAR24219.1 - 5.8e-14 51.6 12.9 0.00027 20.7 0.0 6.1 3 2 3 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 CAR24219.1 - 8.8e-12 45.0 12.5 7.8e-05 22.7 0.2 4.0 4 0 0 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CAR24219.1 - 1.1e-08 34.5 19.7 0.0012 17.9 0.7 4.2 1 1 2 3 3 3 3 Tetratricopeptide repeat MIT PF04212.13 CAR24219.1 - 0.0057 16.5 2.3 11 6.0 0.0 4.7 4 2 0 4 4 3 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 CAR24219.1 - 0.016 14.0 0.7 0.71 8.5 0.1 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 CAR24219.1 - 0.026 13.6 13.8 0.59 9.2 0.5 4.5 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP EnY2 PF10163.4 CAR24220.1 - 7e-29 99.6 0.5 8e-29 99.4 0.3 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Tcell_CD4_Cterm PF12104.3 CAR24220.1 - 0.032 13.8 0.9 11 5.7 0.0 3.2 3 0 0 3 3 3 0 T cell CD4 receptor C terminal region FlgM PF04316.8 CAR24220.1 - 0.14 12.1 0.7 0.56 10.1 0.1 2.3 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM NUDIX PF00293.23 CAR24221.1 - 4.4e-17 61.9 0.0 3.6e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Med1 PF10744.4 CAR24222.1 - 3.9e-42 144.4 2.4 8.8e-39 133.3 0.4 2.1 1 1 1 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Spermine_synth PF01564.12 CAR24223.1 - 1.7e-101 338.2 0.0 2.1e-101 337.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 CAR24223.1 - 0.00033 20.2 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR24223.1 - 0.018 15.5 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CAR24223.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CAR24223.1 - 0.03 14.8 0.0 0.051 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Hist_deacetyl PF00850.14 CAR24224.1 - 4e-68 230.0 0.0 5.7e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_trans_1_4 PF13692.1 CAR24225.1 - 6.5e-16 58.7 0.0 3.1e-15 56.5 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CAR24225.1 - 1.2e-11 44.3 0.0 1.6e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CAR24225.1 - 7e-08 32.7 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CAR24225.1 - 0.0039 17.4 0.0 0.0068 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 EF-hand_1 PF00036.27 CAR24226.1 - 2.5e-30 101.4 3.5 1.7e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CAR24226.1 - 1.4e-27 95.6 0.4 4.5e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CAR24226.1 - 4.7e-26 88.2 2.3 3.5e-08 32.6 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CAR24226.1 - 2.9e-19 68.4 5.7 9.8e-10 37.9 0.0 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CAR24226.1 - 3.9e-17 60.7 2.7 1.9e-07 30.1 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CAR24226.1 - 1.5e-12 47.2 0.0 1.2e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 CAR24226.1 - 4.6e-06 26.1 0.0 0.098 12.2 0.0 3.1 3 1 0 4 4 4 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 CAR24226.1 - 5.3e-06 26.4 0.2 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 CAR24226.1 - 0.00029 20.4 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein p25-alpha PF05517.7 CAR24226.1 - 0.0072 16.5 0.0 0.15 12.2 0.0 2.1 1 1 1 2 2 2 1 p25-alpha TerB PF05099.8 CAR24226.1 - 0.0083 15.8 0.0 0.4 10.4 0.0 2.2 2 1 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_4 PF12763.2 CAR24226.1 - 0.0094 15.6 0.2 0.026 14.2 0.1 1.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand LNS2 PF08235.8 CAR24226.1 - 0.011 15.3 0.0 0.32 10.5 0.0 2.0 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF853 PF05872.7 CAR24226.1 - 0.012 14.0 0.2 0.023 13.0 0.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF4373 PF14297.1 CAR24226.1 - 0.075 13.3 0.1 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) ERAP1_C PF11838.3 CAR24226.1 - 0.086 12.0 0.1 0.13 11.5 0.1 1.2 1 1 0 1 1 1 0 ERAP1-like C-terminal domain RNA_pol_Rpb4 PF03874.11 CAR24226.1 - 0.12 12.3 1.4 0.78 9.7 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 Fe-S_biosyn PF01521.15 CAR24229.1 - 1.9e-13 50.3 0.0 3.2e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis ThiF PF00899.16 CAR24230.1 - 5e-30 104.1 0.1 9.8e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CAR24230.1 - 5.3e-19 67.5 0.1 1.1e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAR24230.1 - 1.1e-08 34.2 1.0 2.4e-08 33.2 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CAR24230.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 CAR24230.1 - 0.049 13.6 0.0 0.37 10.7 0.0 2.2 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 CAR24230.1 - 0.12 12.6 0.1 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Pho88 PF10032.4 CAR24231.1 - 6.8e-84 279.8 0.1 7.5e-84 279.7 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ribosomal_L5_C PF00673.16 CAR24232.1 - 8.6e-24 83.1 0.0 1.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CAR24232.1 - 9e-20 70.2 0.1 2.1e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 BCAS2 PF05700.6 CAR24233.1 - 1.3e-08 34.6 5.7 3.2e-08 33.2 3.9 1.6 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Syntaxin-6_N PF09177.6 CAR24233.1 - 0.59 10.5 4.0 0.54 10.6 1.4 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Arrestin_N PF00339.24 CAR24235.1 - 1.8e-08 34.3 0.0 6.6e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain IF-2B PF01008.12 CAR24236.1 - 1.3e-102 342.6 0.0 2.1e-102 341.8 0.0 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF775 PF05603.7 CAR24236.1 - 1 8.8 5.0 2.1 7.8 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) NARP1 PF12569.3 CAR24236.1 - 1.9 7.1 12.3 2.8 6.5 8.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EPL1 PF10513.4 CAR24236.1 - 5.8 7.1 10.9 2.4 8.3 5.4 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like L51_S25_CI-B8 PF05047.11 CAR24237.1 - 2.5e-14 52.7 0.1 3.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF4149 PF13664.1 CAR24238.1 - 0.002 18.1 0.1 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MAS20 PF02064.10 CAR24239.1 - 1e-18 67.4 0.4 1.3e-17 63.7 0.3 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor SLX9 PF15341.1 CAR24240.1 - 1.7e-24 86.6 10.5 2.4e-24 86.0 7.3 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Ebola_NP PF05505.7 CAR24240.1 - 0.3 9.0 4.3 0.36 8.8 3.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein MRP-S26 PF14943.1 CAR24240.1 - 0.59 9.6 6.6 3.9 7.0 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF3818 PF12825.2 CAR24241.1 - 2.9e-127 424.0 6.3 2.9e-127 424.0 4.4 1.7 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CAR24241.1 - 2.6e-49 166.3 4.9 7.3e-49 164.8 3.4 1.9 1 0 0 1 1 1 1 PX-associated PX PF00787.19 CAR24241.1 - 5.4e-11 42.2 2.5 3.9e-10 39.5 0.0 3.5 3 1 0 3 3 3 1 PX domain Sec7 PF01369.15 CAR24242.1 - 9.7e-37 126.4 0.7 2.9e-36 124.9 0.1 2.0 2 0 0 2 2 2 1 Sec7 domain PH PF00169.24 CAR24242.1 - 0.00034 20.7 0.0 0.0027 17.8 0.0 2.5 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CAR24242.1 - 0.086 13.0 0.0 0.75 10.0 0.0 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.1 CAR24242.1 - 0.11 12.6 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PHF5 PF03660.9 CAR24243.1 - 2.7e-50 168.9 13.2 3e-50 168.7 9.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 CAR24243.1 - 7.1 4.1 10.8 7.8 4.0 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_2 PF13639.1 CAR24244.1 - 7.8e-10 38.4 10.9 7.8e-10 38.4 7.5 3.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CAR24244.1 - 3.6e-07 29.7 10.7 3.6e-07 29.7 7.4 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CAR24244.1 - 1.7e-06 28.0 9.2 1.7e-06 28.0 6.4 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAR24244.1 - 4.9e-06 26.1 10.6 4.9e-06 26.1 7.4 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR24244.1 - 6.7e-06 26.0 11.3 6.7e-06 26.0 7.8 3.0 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR24244.1 - 0.00022 21.0 8.8 0.00022 21.0 6.1 3.4 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CAR24244.1 - 0.01 15.6 5.8 0.01 15.6 4.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 CAR24244.1 - 4.8 7.0 21.0 0.7 9.7 5.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon Cofilin_ADF PF00241.15 CAR24245.1 - 4.7e-27 94.3 0.0 3.1e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF3198 PF11433.3 CAR24245.1 - 0.3 10.9 2.7 1 9.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3198) DUF2404 PF10296.4 CAR24247.1 - 2.4e-29 101.2 0.0 4.8e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 CAR24247.1 - 6.6e-06 26.2 1.9 1.1e-05 25.5 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 CAR24247.1 - 0.0061 16.7 0.0 0.032 14.4 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PI3_PI4_kinase PF00454.22 CAR24248.1 - 5.7e-52 176.5 0.2 1.6e-51 175.0 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 CAR24248.1 - 2.4e-29 101.4 0.5 2.4e-29 101.4 0.4 3.6 5 0 0 5 5 5 1 UME (NUC010) domain FATC PF02260.15 CAR24248.1 - 2.6e-13 49.1 0.1 6.3e-13 47.9 0.1 1.7 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 CAR24248.1 - 0.016 15.1 1.3 0.17 11.8 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) CKS PF01111.14 CAR24249.1 - 2.2e-34 117.0 0.1 2.9e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF2300 PF10062.4 CAR24249.1 - 0.06 13.0 0.1 0.95 9.2 0.1 2.0 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) PRMT5 PF05185.11 CAR24250.1 - 4.3e-151 503.8 0.0 5.2e-151 503.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 CAR24250.1 - 0.0053 16.3 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DIL PF01843.14 CAR24251.1 - 1.1e-12 47.7 7.1 3.2e-06 26.9 0.1 3.2 3 0 0 3 3 3 2 DIL domain SAND PF01342.16 CAR24251.1 - 0.042 13.5 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 SAND domain AA_permease PF00324.16 CAR24252.1 - 2.1e-116 389.1 30.4 2.6e-116 388.7 21.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR24252.1 - 6.4e-19 67.7 30.0 8e-19 67.4 20.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 CAR24252.1 - 0.042 13.5 0.1 0.042 13.5 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) DUF1712 PF08217.6 CAR24254.1 - 5.2e-148 493.9 8.5 6e-148 493.7 5.9 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) SRP54 PF00448.17 CAR24255.1 - 9.5e-80 266.6 3.2 1.1e-78 263.2 0.7 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CAR24255.1 - 1.3e-25 89.6 11.1 1.3e-25 89.6 7.7 4.8 5 1 0 5 5 5 1 Signal peptide binding domain SRP54_N PF02881.14 CAR24255.1 - 4e-15 55.6 2.8 1.2e-14 54.1 1.9 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CAR24255.1 - 3.7e-06 26.5 1.9 1.7e-05 24.3 0.4 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CAR24255.1 - 5.2e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 CAR24255.1 - 1.6e-05 24.2 0.8 0.93 8.6 0.0 3.7 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit MobB PF03205.9 CAR24255.1 - 3.7e-05 23.4 0.1 9.6e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CAR24255.1 - 5.3e-05 22.8 0.2 7.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_31 PF13614.1 CAR24255.1 - 6.2e-05 22.9 0.2 0.038 13.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain CbiA PF01656.18 CAR24255.1 - 0.0001 21.8 1.6 0.00025 20.5 0.1 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 CAR24255.1 - 0.0011 19.7 0.0 0.0024 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR24255.1 - 0.0061 16.6 0.2 0.048 13.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR24255.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain APS_kinase PF01583.15 CAR24255.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase VirE PF05272.6 CAR24255.1 - 0.017 14.5 0.4 0.055 12.9 0.0 2.0 2 0 0 2 2 2 0 Virulence-associated protein E ArgK PF03308.11 CAR24255.1 - 0.022 13.5 0.1 0.076 11.7 0.1 2.0 1 1 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 CAR24255.1 - 0.023 14.2 0.1 0.076 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 CAR24255.1 - 0.03 13.5 0.4 0.82 8.8 0.0 2.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MipZ PF09140.6 CAR24255.1 - 0.03 13.3 0.1 0.89 8.5 0.1 2.6 1 1 0 1 1 1 0 ATPase MipZ AAA_28 PF13521.1 CAR24255.1 - 0.086 12.7 0.3 0.76 9.7 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.1 CAR24255.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CAR24255.1 - 1.3 9.2 6.4 1.4 9.0 0.9 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_D PF01813.12 CAR24256.1 - 0.0055 16.2 5.7 0.0055 16.2 4.0 2.2 1 1 1 2 2 2 1 ATP synthase subunit D Filament PF00038.16 CAR24256.1 - 0.011 15.1 26.5 0.028 13.8 18.4 1.6 1 1 0 1 1 1 0 Intermediate filament protein E3_UbLigase_EDD PF11547.3 CAR24256.1 - 0.056 12.9 0.4 0.16 11.5 0.3 1.7 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD FlaC_arch PF05377.6 CAR24256.1 - 0.47 10.3 14.3 5.4 6.9 0.0 4.9 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 CAR24256.1 - 0.58 9.2 12.7 1 8.4 3.8 2.6 1 1 0 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 CAR24256.1 - 1.2 8.3 28.2 0.38 9.9 15.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding NikR_C PF08753.6 CAR24256.1 - 1.5 8.7 6.2 9.1 6.2 0.2 2.9 3 0 0 3 3 3 0 NikR C terminal nickel binding domain CENP-F_leu_zip PF10473.4 CAR24256.1 - 2.1 8.1 29.1 1.2 8.9 6.4 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.5 CAR24256.1 - 2.4 8.3 19.8 0.93 9.7 7.2 3.6 2 1 1 3 3 3 0 Tup N-terminal IncA PF04156.9 CAR24256.1 - 4.9 6.7 28.3 4.4 6.8 9.1 2.6 1 1 1 2 2 2 0 IncA protein PH PF00169.24 CAR24257.1 - 3.4e-14 52.8 0.2 2.1e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 CAR24257.1 - 0.001 19.2 5.3 0.13 12.5 2.0 3.8 1 1 1 2 2 2 1 Pleckstrin homology domain WD40 PF00400.27 CAR24258.1 - 2.4e-06 27.1 0.0 0.011 15.5 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Ras PF00071.17 CAR24259.1 - 0.0027 17.0 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CAR24259.1 - 0.0029 18.0 0.0 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CAR24259.1 - 0.017 15.1 0.0 0.64 9.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.7 CAR24259.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF87 PF01935.12 CAR24259.1 - 0.17 11.7 0.1 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF258 PF03193.11 CAR24259.1 - 0.2 10.8 0.3 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Atg14 PF10186.4 CAR24260.1 - 2.9e-46 157.7 12.2 1.1e-45 155.9 8.5 1.8 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 CAR24260.1 - 0.02 15.0 4.0 0.02 15.0 2.8 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family eIF3_N PF09440.5 CAR24260.1 - 0.14 12.3 3.7 0.2 11.8 2.1 1.5 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF964 PF06133.6 CAR24260.1 - 0.49 10.4 5.1 0.77 9.7 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF964) DUF342 PF03961.8 CAR24260.1 - 0.57 8.5 2.9 0.74 8.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 CAR24260.1 - 1.1 8.9 8.8 0.4 10.3 4.4 1.4 2 0 0 2 2 2 0 Mnd1 family Prefoldin PF02996.12 CAR24260.1 - 2.5 7.7 7.8 0.17 11.5 0.6 2.4 3 0 0 3 3 3 0 Prefoldin subunit CENP-H PF05837.7 CAR24260.1 - 2.9 8.1 7.6 1.3 9.2 2.9 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ATP-synt_ab PF00006.20 CAR24261.1 - 1.6e-60 204.3 0.0 2.2e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAR24261.1 - 1.4e-16 60.9 0.4 2.9e-16 59.9 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAR24261.1 - 7.4e-14 51.7 2.0 1.7e-13 50.5 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CAR24261.1 - 0.00049 19.9 0.9 0.0018 18.1 0.6 1.9 1 0 0 1 1 1 1 HAS barrel domain Glyco_transf_20 PF00982.16 CAR24263.1 - 9.4e-203 673.9 0.1 1.1e-202 673.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CAR24263.1 - 0.00057 19.3 4.3 0.12 11.7 0.1 3.4 3 1 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CAR24263.1 - 0.0029 17.7 0.1 0.011 15.8 0.1 2.1 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CAR24263.1 - 0.02 14.3 0.4 0.056 12.9 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain PP2C PF00481.16 CAR24264.1 - 2.3e-65 220.5 0.0 8.4e-65 218.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CAR24264.1 - 4.3e-05 23.0 0.0 0.00012 21.5 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CAR24264.1 - 0.0019 17.9 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Tau95 PF09734.4 CAR24265.1 - 7.7e-60 202.8 0.1 1.5e-59 201.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit Ribosomal_L31 PF01197.13 CAR24266.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 Me-amine-dh_H PF06433.6 CAR24266.1 - 0.035 12.7 0.0 0.065 11.8 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DIM1 PF02966.11 CAR24267.1 - 6.2e-70 232.8 1.0 6.9e-70 232.7 0.7 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CAR24267.1 - 0.002 17.8 0.1 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAR24267.1 - 0.025 14.6 0.4 0.049 13.7 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.1 CAR24267.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like tRNA-synt_2b PF00587.20 CAR24268.1 - 4e-71 238.1 0.2 1.7e-70 236.0 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR24268.1 - 1.7e-21 75.9 0.1 5.6e-21 74.2 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain YgaB PF14182.1 CAR24269.1 - 0.0013 18.9 0.1 0.056 13.6 0.2 2.5 2 1 0 2 2 2 1 YgaB-like protein IL6 PF00489.12 CAR24269.1 - 0.037 13.6 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family YkyA PF10368.4 CAR24269.1 - 0.053 12.8 0.6 0.079 12.2 0.4 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein RRM_1 PF00076.17 CAR24270.1 - 2.7e-09 36.5 0.0 2.2e-07 30.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24270.1 - 9e-09 35.1 0.0 2.8e-05 23.9 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24270.1 - 0.00054 19.7 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RecX PF02631.11 CAR24270.1 - 0.052 13.7 1.2 0.16 12.1 0.8 1.9 1 0 0 1 1 1 0 RecX family GTP_EFTU PF00009.22 CAR24271.1 - 6.6e-58 195.2 0.0 1e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAR24271.1 - 2e-36 124.0 0.0 6.2e-36 122.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAR24271.1 - 3.6e-16 59.0 2.1 3.6e-16 59.0 1.5 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CAR24271.1 - 2.6e-05 23.7 0.6 2.6e-05 23.7 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CAR24271.1 - 0.00098 19.0 0.4 0.0034 17.3 0.3 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase CIMR PF00878.13 CAR24272.1 - 2.5e-12 46.8 0.1 3.9e-05 23.4 0.1 2.8 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 CAR24272.1 - 4e-05 23.1 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF3074 PF11274.3 CAR24273.1 - 1.6e-31 109.3 0.8 1.8e-31 109.1 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Opy2 PF09463.5 CAR24274.1 - 2.6e-10 40.1 20.3 4e-10 39.5 14.1 1.3 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.5 CAR24274.1 - 0.029 13.6 0.6 0.069 12.4 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1191 PF06697.7 CAR24274.1 - 0.045 12.5 0.2 0.071 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) GCC2_GCC3 PF07699.8 CAR24274.1 - 2 8.0 13.4 15 5.3 9.3 2.2 1 1 0 1 1 1 0 GCC2 and GCC3 Transketolase_N PF00456.16 CAR24275.1 - 8.9e-152 504.6 0.0 1.7e-151 503.7 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CAR24275.1 - 4.2e-45 153.4 0.0 6.7e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CAR24275.1 - 4.6e-14 52.4 0.0 1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CAR24275.1 - 0.00014 20.8 0.2 0.016 14.1 0.1 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CAR24275.1 - 0.0014 18.2 0.1 0.029 13.9 0.0 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain LMWPc PF01451.16 CAR24276.1 - 2.3e-41 141.3 0.0 2.6e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Not3 PF04065.10 CAR24277.1 - 1.4e-76 256.8 36.9 1.4e-76 256.8 25.6 3.1 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CAR24277.1 - 7.2e-34 116.5 2.1 7.2e-34 116.5 1.5 3.7 4 2 0 4 4 4 1 NOT2 / NOT3 / NOT5 family Peptidase_M3_N PF08439.5 CAR24277.1 - 0.028 14.4 0.6 1.3 9.1 0.0 2.9 2 0 0 2 2 2 0 Oligopeptidase F Cep57_MT_bd PF06657.8 CAR24277.1 - 0.89 9.5 11.9 0.089 12.7 3.1 3.0 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Mito_carr PF00153.22 CAR24278.1 - 2.9e-60 199.9 3.9 6e-22 77.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein RNase_PH PF01138.16 CAR24279.1 - 7.1e-20 71.6 0.0 1.2e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAR24279.1 - 2.9e-07 30.3 0.2 7.1e-07 29.0 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 tRNA-synt_1 PF00133.17 CAR24280.1 - 4.5e-229 761.4 0.0 2.3e-228 759.0 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CAR24280.1 - 5.6e-32 110.6 1.3 1.7e-31 109.0 0.9 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CAR24280.1 - 7.2e-17 61.1 0.2 3.8e-08 32.4 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CAR24280.1 - 3.8e-10 39.3 0.0 6.3e-09 35.3 0.0 3.5 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Lzipper-MIP1 PF14389.1 CAR24280.1 - 0.00095 19.2 1.1 0.0024 17.9 0.8 1.6 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 tRNA-synt_1e PF01406.14 CAR24280.1 - 0.016 14.3 1.8 0.93 8.5 0.0 3.1 3 1 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.17 CAR24281.1 - 1.8e-67 222.8 10.9 2.1e-16 59.3 0.1 6.3 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24281.1 - 3.7e-63 209.4 2.9 1.5e-14 53.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24281.1 - 7.1e-38 128.2 0.1 4.8e-09 35.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CAR24281.1 - 0.036 13.7 1.6 0.67 9.7 0.0 3.9 5 0 0 5 5 5 0 Limkain b1 CwfJ_C_1 PF04677.10 CAR24282.1 - 8.2e-29 99.7 0.1 1.5e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CAR24282.1 - 4.1e-19 68.8 1.5 8.4e-19 67.8 1.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 CAR24283.1 - 1.5e-52 178.3 0.0 1.8e-51 174.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24283.1 - 2.4e-27 95.6 0.1 1.9e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CAR24283.1 - 1.9e-05 25.1 0.1 5.5e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CAR24283.1 - 0.0012 17.8 0.0 0.019 13.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR24283.1 - 0.058 12.4 0.0 0.14 11.1 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR24283.1 - 0.13 12.0 0.1 0.4 10.3 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Nop PF01798.13 CAR24284.1 - 9.9e-37 125.5 0.0 1.9e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CAR24284.1 - 4.3e-31 107.9 5.8 8.1e-31 107.0 4.0 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 CAR24284.1 - 1.3e-07 31.2 0.0 3.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain DUF3474 PF11960.3 CAR24284.1 - 0.21 11.6 0.9 0.64 10.0 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) RNA_pol_A_bac PF01000.21 CAR24285.1 - 5.1e-29 100.6 0.0 1.1e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CAR24285.1 - 1.2e-15 56.3 0.0 1.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FAD_binding_2 PF00890.19 CAR24285.1 - 0.0043 15.9 0.0 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF1746 PF08508.5 CAR24286.1 - 6.9e-06 25.9 1.0 0.13 12.2 0.0 2.8 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1746) Nrap PF03813.9 CAR24287.1 - 0 1190.6 0.7 0 1190.4 0.5 1.0 1 0 0 1 1 1 1 Nrap protein DUF2353 PF09789.4 CAR24288.1 - 0.0028 16.9 16.2 0.0028 16.9 11.3 2.5 2 1 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) WEMBL PF05701.6 CAR24288.1 - 0.0056 15.2 38.3 0.0097 14.4 26.5 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Lipoprotein_20 PF13942.1 CAR24288.1 - 0.013 15.0 1.4 0.013 15.0 0.9 3.4 2 1 2 4 4 4 0 YfhG lipoprotein Reo_sigmaC PF04582.7 CAR24288.1 - 0.26 10.4 10.4 2.5 7.2 2.3 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 CAR24288.1 - 4.5 7.0 40.4 6 6.6 6.7 4.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Catalase PF00199.14 CAR24289.1 - 1e-156 521.4 0.0 1.3e-156 521.1 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CAR24289.1 - 1.9e-11 43.6 0.0 5.2e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive RPN7 PF10602.4 CAR24290.1 - 6.4e-56 188.5 4.4 1.2e-55 187.6 3.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CAR24290.1 - 1.3e-16 60.7 0.1 4.6e-16 59.0 0.0 2.0 1 0 0 1 1 1 1 PCI domain Interferon PF00143.14 CAR24290.1 - 5.1e-05 23.2 0.2 0.0001 22.2 0.1 1.5 1 0 0 1 1 1 1 Interferon alpha/beta domain TPR_12 PF13424.1 CAR24290.1 - 0.00098 19.0 3.6 0.023 14.6 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR24290.1 - 0.0042 16.7 0.5 0.013 15.2 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.1 CAR24290.1 - 0.0055 15.7 0.8 0.013 14.6 0.2 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR24290.1 - 0.012 16.2 0.0 0.16 12.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.8 CAR24290.1 - 0.022 14.4 0.2 0.059 13.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF357) PCI_Csn8 PF10075.4 CAR24290.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 CAR24290.1 - 0.039 13.7 0.0 3.3 7.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CAR24290.1 - 0.044 13.7 2.6 0.2 11.6 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat GNVR PF13807.1 CAR24290.1 - 0.12 12.0 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase TPR_16 PF13432.1 CAR24290.1 - 0.13 12.9 0.2 0.7 10.6 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CAR24290.1 - 0.14 12.4 1.0 0.39 11.0 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat EMP24_GP25L PF01105.19 CAR24291.1 - 3.5e-33 114.8 0.0 4.8e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1963 PF09234.5 CAR24292.1 - 1.3e-56 192.3 0.1 1.6e-56 192.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) TP6A_N PF04406.9 CAR24293.1 - 2.7e-10 39.7 3.8 5.2e-10 38.8 0.1 3.1 4 0 0 4 4 4 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 CAR24293.1 - 2.5e-05 24.2 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) TauD PF02668.11 CAR24294.1 - 6.6e-52 176.7 0.0 9.2e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 CAR24294.1 - 0.017 15.6 0.0 4 8.0 0.0 3.3 3 1 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily DUF971 PF06155.7 CAR24294.1 - 0.09 13.2 0.0 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF971) Pet127 PF08634.5 CAR24295.1 - 1.6e-111 371.8 8.6 2.6e-111 371.1 6.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 PQ-loop PF04193.9 CAR24296.1 - 2.1e-09 36.7 14.6 2.1e-08 33.6 1.5 3.3 3 1 0 3 3 3 2 PQ loop repeat ARD PF03079.9 CAR24297.1 - 1.8e-43 148.2 0.0 2e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CAR24297.1 - 9.8e-11 41.0 0.0 1.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CAR24297.1 - 4.7e-07 29.5 0.0 7.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 CAR24297.1 - 0.00091 18.6 0.0 0.0025 17.2 0.0 1.6 2 0 0 2 2 2 1 Cupin Cupin_8 PF13621.1 CAR24297.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Glyco_hydro_72 PF03198.9 CAR24298.1 - 1.4e-141 471.0 9.8 1.9e-141 470.6 6.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 CAR24298.1 - 1.6e-05 24.2 0.3 6.6e-05 22.2 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apt1 PF10351.4 CAR24298.1 - 3.5 6.3 6.8 4.7 5.9 4.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.4 CAR24298.1 - 4.4 5.4 9.9 5.8 5.0 6.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF515 PF04415.7 CAR24298.1 - 9.4 4.3 15.0 19 3.3 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) bZIP_1 PF00170.16 CAR24299.1 - 9.6e-08 31.8 13.5 1.6e-06 27.9 5.2 2.3 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 CAR24299.1 - 1.2e-05 25.0 0.6 1.2e-05 25.0 0.4 2.0 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 CENP-F_leu_zip PF10473.4 CAR24299.1 - 0.0087 15.9 2.8 0.015 15.1 1.9 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_2 PF12848.2 CAR24299.1 - 0.032 14.0 5.6 0.07 12.9 3.9 1.5 1 0 0 1 1 1 0 ABC transporter DUF812 PF05667.6 CAR24299.1 - 0.04 12.4 1.1 0.048 12.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_Maf PF03131.12 CAR24299.1 - 0.04 14.2 6.7 0.56 10.5 5.5 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Laminin_II PF06009.7 CAR24299.1 - 0.076 12.7 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF641 PF04859.7 CAR24299.1 - 0.08 12.6 5.0 0.12 12.0 3.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4094 PF13334.1 CAR24299.1 - 0.2 12.0 2.0 16 5.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) bZIP_2 PF07716.10 CAR24299.1 - 0.48 10.2 15.2 3 7.7 5.5 2.5 1 1 1 2 2 2 0 Basic region leucine zipper AAA_13 PF13166.1 CAR24299.1 - 0.59 8.5 3.4 0.78 8.1 2.4 1.1 1 0 0 1 1 1 0 AAA domain CENP-Q PF13094.1 CAR24299.1 - 4.2 7.3 8.5 3.5 7.6 4.6 1.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 CAR24299.1 - 6.5 6.2 6.9 10 5.6 4.8 1.2 1 0 0 1 1 1 0 IncA protein WSC PF01822.14 CAR24300.1 - 2.6e-13 49.6 16.9 2.6e-13 49.6 11.7 2.8 2 1 0 2 2 2 1 WSC domain DUF605 PF04652.11 CAR24300.1 - 0.0014 18.0 14.6 0.0017 17.8 10.1 1.2 1 0 0 1 1 1 1 Vta1 like Nitrate_red_gam PF02665.9 CAR24300.1 - 0.0063 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Nitrate reductase gamma subunit TFIIA PF03153.8 CAR24300.1 - 0.14 12.0 7.0 0.17 11.7 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Beta-APP PF03494.8 CAR24300.1 - 1.6 8.2 4.1 3 7.3 2.8 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF2413 PF10310.4 CAR24300.1 - 1.7 7.3 15.3 2.6 6.7 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Apt1 PF10351.4 CAR24300.1 - 9.9 4.8 16.0 15 4.2 11.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2408 PF10303.4 CAR24301.1 - 3.3e-73 244.1 11.2 5.1e-48 162.5 0.6 4.8 3 2 2 5 5 5 3 Protein of unknown function (DUF2408) MtrG PF04210.8 CAR24301.1 - 0.037 13.7 3.2 5.6 6.7 0.0 3.8 5 0 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase, subunit G GshA PF08886.6 CAR24301.1 - 0.057 11.7 0.0 0.093 11.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase AATF-Che1 PF13339.1 CAR24301.1 - 0.34 11.0 11.9 0.26 11.4 1.5 4.2 5 0 0 5 5 5 0 Apoptosis antagonizing transcription factor NPV_P10 PF05531.7 CAR24301.1 - 1.1 9.5 6.9 23 5.3 0.1 4.9 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein AhpC-TSA PF00578.16 CAR24302.1 - 9.8e-29 99.5 0.0 1.5e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAR24302.1 - 1.1e-21 76.8 0.1 1.7e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CAR24302.1 - 0.00035 20.4 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF4102 PF13356.1 CAR24302.1 - 0.0063 16.3 1.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4102) Adap_comp_sub PF00928.16 CAR24303.1 - 3e-90 301.8 0.1 4.4e-90 301.3 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CAR24303.1 - 4.4e-05 23.2 0.7 7.8e-05 22.4 0.5 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Lys PF00062.15 CAR24303.1 - 0.093 12.7 0.1 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 C-type lysozyme/alpha-lactalbumin family TPP1 PF10341.4 CAR24304.1 - 0.00068 19.5 0.0 0.0009 19.1 0.0 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Urm1 PF09138.6 CAR24305.1 - 5.1e-36 122.6 0.5 5.7e-36 122.5 0.4 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CAR24305.1 - 0.01 16.2 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 0 ThiS family YchF-GTPase_C PF06071.8 CAR24305.1 - 0.071 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF933) PDZ_2 PF13180.1 CAR24306.1 - 0.011 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 PDZ domain GRASP55_65 PF04495.9 CAR24306.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain bZIP_1 PF00170.16 CAR24307.1 - 2.1e-14 53.2 9.1 3.2e-14 52.6 6.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CAR24307.1 - 1.8e-12 46.8 9.6 2.8e-12 46.2 6.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CAR24307.1 - 0.00057 20.1 6.1 0.001 19.2 4.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor TSC22 PF01166.13 CAR24307.1 - 0.068 13.1 0.6 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF972 PF06156.8 CAR24307.1 - 0.13 12.5 1.0 0.22 11.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF479 PF04336.7 CAR24307.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF479 DivIC PF04977.10 CAR24307.1 - 0.17 11.3 3.4 0.29 10.6 2.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Gti1_Pac2 PF09729.4 CAR24308.1 - 6e-46 156.3 0.3 3.6e-39 134.3 0.0 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family Med3 PF11593.3 CAR24308.1 - 0.44 9.7 8.7 0.55 9.4 6.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mito_carr PF00153.22 CAR24309.1 - 7.3e-74 243.5 1.1 2.3e-25 88.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioredoxin PF00085.15 CAR24310.1 - 6.7e-22 77.1 1.4 6.9e-18 64.2 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 CAR24310.1 - 5.1e-06 26.4 4.0 0.00018 21.3 0.2 3.4 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CAR24310.1 - 0.0081 16.2 1.1 0.08 13.0 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like SNARE PF05739.14 CAR24311.1 - 1.6e-07 30.8 0.2 2.4e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 SNARE domain Bacillus_HBL PF05791.6 CAR24311.1 - 0.031 13.6 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Use1 PF09753.4 CAR24311.1 - 0.062 12.7 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 ParA PF10609.4 CAR24312.1 - 6.6e-38 128.4 0.0 1.4e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CAR24312.1 - 3.4e-18 65.7 0.0 5.1e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CAR24312.1 - 7.1e-07 28.5 0.2 6.4e-06 25.4 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 CAR24312.1 - 1.4e-06 27.5 0.0 1.3e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CAR24312.1 - 3.3e-06 27.1 0.0 9.6e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CAR24312.1 - 0.0017 17.6 0.3 0.026 13.7 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 CAR24312.1 - 0.0032 16.8 0.0 0.008 15.5 0.0 1.7 1 1 0 1 1 1 1 YhjQ protein ArgK PF03308.11 CAR24312.1 - 0.0039 16.0 0.2 0.0061 15.3 0.2 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 CAR24312.1 - 0.01 15.2 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.1 CAR24312.1 - 0.055 13.0 0.5 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CAR24312.1 - 0.07 12.5 0.2 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain UAA PF08449.6 CAR24314.1 - 2.1e-74 250.1 18.8 2.5e-74 249.9 13.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CAR24314.1 - 2.2e-06 27.7 19.9 0.00062 19.8 4.2 2.7 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CAR24314.1 - 5.3e-06 26.1 8.4 5.3e-06 26.1 5.8 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF3525 PF12039.3 CAR24314.1 - 0.0052 15.3 0.0 0.0075 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3525) DUF914 PF06027.7 CAR24314.1 - 0.0078 15.0 6.9 0.031 13.1 0.5 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 CAR24314.1 - 1.8 8.7 20.6 1.3 9.2 2.4 3.0 3 1 1 4 4 4 0 Multidrug resistance efflux transporter Prefoldin_2 PF01920.15 CAR24315.1 - 5.3e-22 77.5 2.6 5.8e-22 77.4 1.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.4 CAR24315.1 - 0.004 17.0 3.7 0.17 11.7 0.2 2.0 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 CAR24315.1 - 0.023 14.3 1.8 2.2 7.9 0.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit Phi-29_GP3 PF05435.6 CAR24315.1 - 0.028 13.6 0.5 0.041 13.1 0.2 1.5 1 1 0 1 1 1 0 Phi-29 DNA terminal protein GP3 DUF904 PF06005.7 CAR24315.1 - 0.043 14.1 4.2 2.8 8.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 CAR24315.1 - 0.099 12.5 2.3 0.21 11.5 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 CAR24315.1 - 0.099 12.1 3.3 1.2 8.6 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF342 PF03961.8 CAR24315.1 - 0.15 10.4 2.6 0.28 9.5 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 CAR24315.1 - 0.41 10.3 4.8 2.5 7.8 0.7 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ax_dynein_light PF10211.4 CAR24315.1 - 0.54 10.0 3.3 11 5.7 0.1 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DDOST_48kD PF03345.9 CAR24316.1 - 1.5e-134 448.7 1.9 1.7e-134 448.5 1.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Exonuc_VII_S PF02609.11 CAR24317.1 - 0.0084 15.8 0.8 0.015 15.0 0.5 1.5 1 0 0 1 1 1 1 Exonuclease VII small subunit Paralemmin PF03285.10 CAR24317.1 - 0.013 14.9 1.4 0.018 14.5 1.0 1.2 1 0 0 1 1 1 0 Paralemmin CK2S PF15011.1 CAR24317.1 - 0.013 15.2 0.5 0.018 14.8 0.3 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate AKNA PF12443.3 CAR24317.1 - 0.027 14.5 1.1 0.039 13.9 0.7 1.3 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF327 PF03885.8 CAR24317.1 - 0.027 14.2 1.6 0.036 13.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF327) PspA_IM30 PF04012.7 CAR24317.1 - 0.031 13.6 0.6 0.034 13.5 0.4 1.1 1 0 0 1 1 1 0 PspA/IM30 family DMPK_coil PF08826.5 CAR24317.1 - 0.038 13.8 1.6 0.063 13.1 1.1 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like PilJ PF13675.1 CAR24317.1 - 0.047 13.9 0.3 0.052 13.8 0.2 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Rootletin PF15035.1 CAR24317.1 - 0.057 13.3 0.8 0.068 13.1 0.5 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UPF0449 PF15136.1 CAR24317.1 - 0.072 13.3 0.5 0.094 12.9 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Uds1 PF15456.1 CAR24317.1 - 0.074 13.0 0.6 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 Up-regulated During Septation V_ATPase_I PF01496.14 CAR24317.1 - 0.1 10.4 1.4 0.11 10.3 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3473 PF11959.3 CAR24317.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) DUF948 PF06103.6 CAR24317.1 - 0.14 12.0 0.1 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DASH_Dad2 PF08654.5 CAR24317.1 - 0.78 9.7 3.5 1.1 9.2 1.0 1.9 1 1 1 2 2 2 0 DASH complex subunit Dad2 Syja_N PF02383.13 CAR24318.1 - 1.1e-63 215.0 0.1 1.6e-63 214.3 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CAR24318.1 - 1.9e-23 83.6 0.0 3e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.26 CAR24319.1 - 8e-19 67.6 0.1 2.8e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 CAR24319.1 - 1.5e-08 34.8 0.0 5.2e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAR24319.1 - 1.4e-07 31.0 0.1 3.5e-06 26.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CAR24319.1 - 1.7e-06 27.6 0.2 0.024 14.8 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CAR24319.1 - 2.2e-06 27.9 0.1 8.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAR24319.1 - 0.0003 20.9 0.1 0.00091 19.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RRM_1 PF00076.17 CAR24321.1 - 6.2e-14 51.3 0.1 1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24321.1 - 1.6e-12 47.1 0.0 2.9e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24321.1 - 2.7e-09 36.7 0.1 8.5e-09 35.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop16 PF09420.5 CAR24322.1 - 2.5e-55 187.0 2.9 2.9e-55 186.8 2.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Myb_DNA-bind_6 PF13921.1 CAR24322.1 - 0.6 10.2 3.6 0.36 10.9 0.8 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain PMI_typeI PF01238.16 CAR24323.1 - 2e-151 504.2 0.0 2.3e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 CAR24323.1 - 0.00065 19.3 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Hexapep PF00132.19 CAR24324.1 - 0.00067 19.0 7.7 0.38 10.3 0.3 5.3 5 1 1 6 6 6 4 Bacterial transferase hexapeptide (six repeats) GDA1_CD39 PF01150.12 CAR24325.1 - 1.1e-132 442.6 0.0 1.6e-132 442.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TauE PF01925.14 CAR24325.1 - 0.019 14.3 0.4 0.031 13.7 0.3 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DsbD_2 PF13386.1 CAR24325.1 - 0.11 12.1 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region TFIIB PF00382.14 CAR24326.1 - 8.2e-47 156.8 5.2 9.7e-26 89.3 0.8 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CAR24326.1 - 7.3e-12 44.4 0.7 1.3e-11 43.6 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 CAR24326.1 - 0.00099 19.0 0.4 0.0033 17.3 0.0 2.1 2 1 1 3 3 3 1 Cyclin, C-terminal domain ATP-synt_10 PF05176.9 CAR24326.1 - 0.055 12.7 0.1 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP10 protein DUF1461 PF07314.6 CAR24326.1 - 0.12 12.0 0.1 1.8 8.2 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1461) GN3L_Grn1 PF08701.6 CAR24327.1 - 4.5e-24 84.1 14.3 4.5e-24 84.1 9.9 1.9 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 CAR24327.1 - 6.3e-22 77.7 0.2 6.7e-16 58.2 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR24327.1 - 3.1e-09 36.2 0.2 2.4e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR24327.1 - 7.5e-05 22.6 6.2 0.18 11.5 0.1 3.6 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 CAR24327.1 - 0.00038 19.9 0.3 0.27 10.6 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CAR24327.1 - 0.0015 17.7 0.0 0.0053 15.8 0.0 1.9 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CAR24327.1 - 0.0023 17.1 0.1 0.0046 16.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CAR24327.1 - 0.0024 18.1 0.3 0.08 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CAR24327.1 - 0.021 13.5 0.0 0.05 12.3 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 CAR24327.1 - 0.035 14.5 0.5 0.94 9.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 CAR24327.1 - 0.1 12.0 0.1 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GBP PF02263.14 CAR24327.1 - 0.11 11.5 0.3 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.1 CAR24327.1 - 0.12 12.3 0.9 6.3 6.7 0.0 2.7 1 1 2 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 CAR24327.1 - 0.27 11.3 1.1 22 5.1 0.1 3.3 3 1 0 3 3 3 0 AAA domain LRR_4 PF12799.2 CAR24328.1 - 7.6e-15 54.1 20.5 9.7e-06 25.0 1.1 5.9 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CAR24328.1 - 5.7e-14 51.6 15.7 5.2e-05 22.9 1.3 4.7 2 2 2 4 4 4 4 Leucine rich repeat CAP_GLY PF01302.20 CAR24328.1 - 1.5e-13 50.2 0.0 2.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_7 PF13504.1 CAR24328.1 - 7.5e-09 34.3 10.7 1.8 9.0 0.0 8.9 9 0 0 9 9 9 2 Leucine rich repeat LRR_6 PF13516.1 CAR24328.1 - 3.9e-08 32.5 17.0 1.9 8.8 0.1 8.6 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.28 CAR24328.1 - 4.2e-06 26.0 22.1 1.8 8.8 0.0 8.8 6 2 2 8 8 8 3 Leucine Rich Repeat FNIP PF05725.7 CAR24328.1 - 0.003 17.4 0.1 0.018 14.9 0.0 2.5 3 1 0 3 3 3 1 FNIP Repeat PUA PF01472.15 CAR24329.1 - 1.6e-20 72.6 0.0 2.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 CAR24329.1 - 0.0084 15.8 0.1 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) Helicase_C PF00271.26 CAR24330.1 - 1.6e-20 72.7 0.1 5.5e-20 71.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR24330.1 - 5e-20 71.6 0.0 1.5e-18 66.8 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 CAR24330.1 - 1.9e-17 63.7 3.7 8.4e-17 61.5 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CAR24330.1 - 4.4e-06 25.6 0.1 1.8e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain PhoH PF02562.11 CAR24330.1 - 0.00058 19.1 0.1 0.0021 17.3 0.0 1.9 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 CAR24330.1 - 0.0027 17.8 0.0 0.019 15.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain Sec3_C PF09763.4 CAR24331.1 - 6e-136 454.3 9.4 6e-136 454.3 6.5 2.1 2 1 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CAR24331.1 - 2.1e-27 94.8 0.1 7.1e-27 93.1 0.0 1.9 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 CAR24331.1 - 8.5e-08 31.1 3.5 1.5e-07 30.3 2.4 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C_2 PF15278.1 CAR24331.1 - 0.0094 16.0 1.0 0.038 14.0 0.7 2.2 1 0 0 1 1 1 1 Sec3 exocyst complex subunit NTF2 PF02136.15 CAR24332.1 - 8.9e-34 116.3 0.4 1e-33 116.2 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 CAR24332.1 - 0.0061 15.6 0.1 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) DUF3210 PF11489.3 CAR24333.1 - 3.3e-09 36.0 54.8 6e-09 35.1 38.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3210) DnaJ-X PF14308.1 CAR24334.1 - 1.1e-59 201.1 6.8 1.1e-59 201.1 4.7 2.3 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 CAR24334.1 - 3.9e-23 80.9 2.1 3.9e-23 80.9 1.5 3.4 3 0 0 3 3 3 1 DnaJ domain SSP160 PF06933.6 CAR24334.1 - 0.039 11.9 0.4 0.057 11.4 0.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_6 PF03737.10 CAR24335.1 - 9.2e-31 106.7 0.0 1.2e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase RRM_1 PF00076.17 CAR24336.1 - 3e-19 68.4 0.0 4.1e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24336.1 - 9.4e-13 47.9 0.0 1.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24336.1 - 7.2e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_4 PF12763.2 CAR24337.1 - 2e-25 88.5 0.0 1.9e-13 50.0 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CAR24337.1 - 4.4e-08 33.1 0.0 2.2e-06 27.7 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair DUF1720 PF08226.6 CAR24337.1 - 1.9e-07 31.0 123.0 8.6e-05 22.5 31.6 10.4 4 3 4 8 8 8 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 CAR24337.1 - 4.4e-06 25.5 0.0 0.0015 17.7 0.0 3.3 3 0 0 3 3 3 1 EF hand CCDC155 PF14662.1 CAR24337.1 - 0.00087 18.9 13.2 0.0022 17.6 0.3 3.2 3 0 0 3 3 3 2 Coiled-coil region of CCDC155 EF-hand_6 PF13405.1 CAR24337.1 - 0.0011 18.6 0.2 0.3 11.1 0.0 3.4 4 0 0 4 4 4 1 EF-hand domain DUF1664 PF07889.7 CAR24337.1 - 3.6 7.3 5.0 7.5 6.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 CAR24337.1 - 3.6 8.0 12.0 11 6.5 3.1 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mannosyl_trans3 PF11051.3 CAR24338.1 - 2.8e-59 200.7 0.0 3.8e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative bZIP_2 PF07716.10 CAR24339.1 - 7.4e-09 35.2 5.6 7.4e-09 35.2 3.9 2.9 3 1 1 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.16 CAR24339.1 - 0.0059 16.5 11.0 0.0059 16.5 7.6 3.0 2 1 0 2 2 2 1 bZIP transcription factor Ferritin-like PF12902.2 CAR24339.1 - 0.16 11.5 5.3 0.058 12.9 1.9 1.5 2 0 0 2 2 2 0 Ferritin-like JHBP PF06585.6 CAR24339.1 - 0.45 9.2 3.0 0.41 9.4 0.5 2.0 2 1 1 3 3 3 0 Haemolymph juvenile hormone binding protein (JHBP) VSG_B PF13206.1 CAR24339.1 - 1.7 7.6 6.3 0.51 9.4 2.3 1.6 2 0 0 2 2 2 0 Trypanosomal VSG domain Proteasome PF00227.21 CAR24341.1 - 5.5e-57 192.1 0.0 7.2e-57 191.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR24341.1 - 7.6e-14 50.7 0.1 1.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature APC_CDC26 PF10471.4 CAR24341.1 - 0.038 14.7 1.8 0.071 13.8 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 TOM13 PF08219.6 CAR24342.1 - 7.5e-27 92.9 0.0 1.1e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Rpr2 PF04032.11 CAR24343.1 - 2.2e-16 59.4 0.9 2.9e-16 59.0 0.6 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain MVIN PF03023.9 CAR24344.1 - 0.05 12.0 0.8 0.066 11.6 0.5 1.1 1 0 0 1 1 1 0 MviN-like protein DUF3488 PF11992.3 CAR24344.1 - 0.19 10.2 0.8 0.27 9.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF1746 PF08508.5 CAR24344.1 - 0.95 9.4 6.3 2.2 8.2 4.4 1.6 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1746) LETM1 PF07766.8 CAR24345.1 - 1e-102 342.8 3.3 1.9e-102 341.9 2.3 1.5 1 0 0 1 1 1 1 LETM1-like protein DUF3827 PF12877.2 CAR24345.1 - 0.73 7.8 14.7 1.3 7.0 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Cellulase PF00150.13 CAR24346.1 - 2.9e-13 49.6 0.0 1.9e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_14 PF01373.12 CAR24346.1 - 0.013 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.14 CAR24346.1 - 0.023 14.0 0.1 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DNA_primase_S PF01896.14 CAR24347.1 - 5.8e-54 181.8 0.7 1.1e-53 180.9 0.5 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Proteasome PF00227.21 CAR24348.1 - 1.4e-44 151.6 0.0 1.6e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HA2 PF04408.18 CAR24349.1 - 2.3e-26 91.7 1.3 2.8e-26 91.5 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR24349.1 - 1.2e-25 89.5 0.0 3e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 CAR24349.1 - 1.6e-13 50.5 0.2 3.6e-13 49.3 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 CAR24349.1 - 1.8e-11 43.7 0.4 6e-11 42.0 0.0 2.2 2 0 0 2 2 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAR24349.1 - 5e-06 26.6 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CAR24349.1 - 6.6e-06 25.7 0.1 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CAR24349.1 - 0.00061 18.7 0.0 0.0023 16.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 CAR24349.1 - 0.0056 16.5 0.1 0.057 13.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CAR24349.1 - 0.0066 16.7 6.4 0.14 12.4 0.2 3.4 2 2 1 3 3 3 1 ABC transporter AAA_30 PF13604.1 CAR24349.1 - 0.0067 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CAR24349.1 - 0.0088 15.5 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 CAR24349.1 - 0.011 15.8 0.0 0.095 12.7 0.0 2.5 4 0 0 4 4 3 0 Sigma-54 interaction domain NB-ARC PF00931.17 CAR24349.1 - 0.025 13.4 0.1 0.07 11.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF3878 PF12994.2 CAR24349.1 - 0.063 12.4 0.4 0.12 11.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) AAA_19 PF13245.1 CAR24349.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 CAR24349.1 - 0.16 11.4 0.1 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain NAD_binding_8 PF13450.1 CAR24350.1 - 4e-10 39.5 0.0 9e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CAR24350.1 - 1.3e-06 27.7 0.0 1.8e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 CAR24350.1 - 7.3e-06 25.1 0.2 1.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CAR24350.1 - 0.00031 19.9 0.1 0.00031 19.9 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 CAR24350.1 - 0.00033 20.9 0.1 0.00083 19.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CAR24350.1 - 0.00083 19.2 0.0 0.002 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR24350.1 - 0.00099 19.2 0.1 0.0021 18.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CAR24350.1 - 0.008 15.0 0.1 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CAR24350.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 CAR24350.1 - 0.02 14.6 0.0 0.091 12.5 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Mqo PF06039.10 CAR24350.1 - 0.044 11.9 0.0 0.072 11.2 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 CAR24350.1 - 0.13 11.2 0.1 0.23 10.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain RRM_5 PF13893.1 CAR24351.1 - 9.4e-11 41.3 0.0 1.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR24351.1 - 1.1e-09 37.8 0.3 2e-09 36.9 0.2 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24351.1 - 1.5e-05 24.8 0.1 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pcc1 PF09341.5 CAR24351.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Pcc1 AMP-binding PF00501.23 CAR24352.1 - 2.7e-68 230.2 0.0 3.4e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GCR1_C PF12550.3 CAR24353.1 - 3.9e-20 71.5 1.5 8.3e-20 70.4 1.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Lzipper-MIP1 PF14389.1 CAR24353.1 - 0.0036 17.3 2.4 0.021 14.9 0.6 2.5 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 USP8_interact PF08941.5 CAR24353.1 - 0.024 13.9 0.2 0.11 11.8 0.2 2.0 2 0 0 2 2 2 0 USP8 interacting DUF4510 PF14971.1 CAR24353.1 - 0.16 12.1 1.1 0.45 10.6 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) Atg14 PF10186.4 CAR24353.1 - 0.21 10.4 3.6 0.072 12.0 0.3 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 CAR24353.1 - 0.72 8.9 4.0 2.1 7.3 0.6 2.1 2 0 0 2 2 2 0 Tropomyosin EB1 PF03271.12 CAR24354.1 - 2.9e-18 65.6 0.3 7.8e-18 64.2 0.2 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CAR24354.1 - 1.3e-05 25.2 1.1 3.6e-05 23.7 0.3 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF1202 PF06717.6 CAR24354.1 - 0.02 14.1 0.1 0.03 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DivIC PF04977.10 CAR24354.1 - 0.04 13.3 2.5 0.081 12.4 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Peptidase_M41 PF01434.13 CAR24355.1 - 2.8e-75 252.4 0.1 3.9e-75 251.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CAR24355.1 - 2.2e-42 144.4 0.0 5.3e-42 143.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CAR24355.1 - 6.7e-08 32.6 0.1 1.6e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CAR24355.1 - 0.0003 21.6 0.0 0.0013 19.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR24355.1 - 0.00058 20.0 0.5 0.11 12.6 0.1 3.5 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 CAR24355.1 - 0.0029 16.4 0.1 0.0058 15.3 0.1 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 CAR24355.1 - 0.0031 17.2 0.8 0.01 15.5 0.6 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CAR24355.1 - 0.0068 16.1 0.1 0.03 14.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR24355.1 - 0.0096 15.9 0.6 0.076 13.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 CAR24355.1 - 0.01 14.9 0.5 0.056 12.5 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.7 CAR24355.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CAR24355.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 CAR24355.1 - 0.024 14.9 0.5 0.19 12.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 CAR24355.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CAR24355.1 - 0.052 13.4 0.3 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CAR24355.1 - 0.12 11.5 0.3 0.38 9.8 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CAR24355.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.14 CAR24356.1 - 6.5e-16 58.3 4.2 3.1e-15 56.1 2.9 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR24356.1 - 0.0019 18.5 1.7 0.0044 17.3 1.2 1.6 1 1 0 1 1 1 1 HMG-box domain Ribosomal_S5 PF00333.15 CAR24357.1 - 5.9e-25 86.7 0.1 1.1e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CAR24357.1 - 3.9e-17 61.2 0.0 9.5e-17 60.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain SURF1 PF02104.10 CAR24358.1 - 1.5e-64 217.7 0.1 2e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 SURF1 family V-set PF07686.12 CAR24358.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin V-set domain DASH_Dam1 PF08653.5 CAR24359.1 - 6.4e-29 99.4 0.6 1.4e-28 98.4 0.4 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 DNA_photolyase PF00875.13 CAR24359.1 - 0.041 13.6 0.3 0.082 12.6 0.2 1.5 1 1 0 1 1 1 0 DNA photolyase DUF383 PF04063.9 CAR24359.1 - 0.075 12.5 0.2 0.23 10.9 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF383) Ctr PF04145.10 CAR24360.1 - 3.9e-26 91.8 3.4 3.9e-26 91.8 2.4 2.2 2 0 0 2 2 2 1 Ctr copper transporter family Tetraspannin PF00335.15 CAR24360.1 - 0.073 12.3 1.9 0.14 11.4 0.9 1.7 2 0 0 2 2 2 0 Tetraspanin family SH2_2 PF14633.1 CAR24361.1 - 3e-102 340.3 3.0 3e-102 340.3 2.1 2.3 3 0 0 3 3 3 1 SH2 domain YqgF PF14639.1 CAR24361.1 - 3.2e-59 198.7 0.0 1e-58 197.2 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 CAR24361.1 - 7.6e-48 161.3 3.9 7.6e-48 161.3 2.7 3.1 4 0 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 CAR24361.1 - 9e-43 144.6 0.1 3.5e-42 142.7 0.1 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CAR24361.1 - 4.2e-36 123.5 1.9 4.2e-36 123.5 1.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 CAR24361.1 - 1.4e-23 82.8 22.3 1.4e-23 82.8 15.4 5.2 4 1 2 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.19 CAR24361.1 - 7e-12 44.9 0.1 2.2e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 SH2 domain 6PF2K PF01591.13 CAR24362.1 - 3e-45 154.0 0.0 2.1e-32 111.9 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase AAA_33 PF13671.1 CAR24362.1 - 3.8e-07 30.0 0.6 6.1e-06 26.1 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR24362.1 - 0.099 13.4 0.0 0.22 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain LETM1 PF07766.8 CAR24363.1 - 3.8e-96 321.2 3.7 6.3e-96 320.5 2.6 1.3 1 0 0 1 1 1 1 LETM1-like protein RNA_pol_3_Rpc31 PF11705.3 CAR24363.1 - 0.43 10.4 7.6 9.9 6.0 2.7 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Mito_carr PF00153.22 CAR24364.1 - 1.5e-55 184.8 4.4 1.8e-20 72.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LSM14 PF12701.2 CAR24365.1 - 1.7e-23 82.2 5.1 1e-22 79.7 3.5 2.3 1 1 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 CAR24365.1 - 9.2e-09 35.7 10.0 9.2e-09 35.7 7.0 3.7 3 1 0 3 3 3 1 FDF domain SM-ATX PF14438.1 CAR24365.1 - 0.00065 19.5 1.4 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 Ataxin 2 SM domain CDC27 PF09507.5 CAR24365.1 - 0.011 15.0 19.9 0.013 14.7 13.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Med15 PF09606.5 CAR24365.1 - 0.26 9.4 43.9 0.3 9.2 30.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tom22 PF04281.8 CAR24365.1 - 2.4 7.7 13.1 0.53 9.8 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 BAF1_ABF1 PF04684.8 CAR24365.1 - 5.9 5.6 19.9 9.3 4.9 13.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Acetyltransf_1 PF00583.19 CAR24366.1 - 1.1e-08 35.0 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CAR24366.1 - 0.0005 19.7 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CAR24366.1 - 0.0048 17.0 0.0 0.016 15.3 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR24366.1 - 0.057 13.5 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hen1_L PF12623.2 CAR24366.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 HTH_IclR PF09339.5 CAR24367.1 - 0.00059 19.3 0.8 0.0021 17.6 0.4 2.1 1 1 1 2 2 2 1 IclR helix-turn-helix domain CNH PF00780.17 CAR24367.1 - 0.0022 17.4 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 CNH domain WD40 PF00400.27 CAR24367.1 - 0.18 11.7 0.5 10 6.1 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribosom_S12_S23 PF00164.20 CAR24368.1 - 8.5e-41 138.2 0.4 1e-40 137.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Med26 PF08711.6 CAR24369.1 - 2.3e-14 52.5 0.1 1.6e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain PilJ PF13675.1 CAR24369.1 - 0.13 12.6 4.8 0.42 10.9 3.3 1.9 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Phasin PF05597.6 CAR24369.1 - 0.35 10.6 7.3 0.039 13.7 1.4 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF843 PF05814.6 CAR24369.1 - 2.2 8.1 3.8 3 7.7 0.0 2.7 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Tom5 PF10642.4 CAR24370.1 - 2.3e-24 84.7 0.1 2.5e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nucleoporin_FG PF13634.1 CAR24372.1 - 4.3e-48 162.2 233.9 3.3e-13 49.8 29.7 4.3 1 1 4 5 5 5 5 Nucleoporin FG repeat region Nup54 PF13874.1 CAR24372.1 - 2.4e-41 140.7 2.9 2.4e-41 140.7 2.0 2.2 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF4591 PF15261.1 CAR24372.1 - 2.2 8.5 6.9 3.5 7.9 4.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4591) COG2 PF06148.6 CAR24373.1 - 1.3e-08 34.7 4.6 1.3e-08 34.7 3.2 1.7 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.8 CAR24373.1 - 0.014 15.7 2.8 0.42 11.0 0.4 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) zf-C3HC4 PF00097.20 CAR24373.1 - 0.05 13.2 0.6 0.13 11.8 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kinesin-relat_1 PF12711.2 CAR24373.1 - 0.076 13.4 2.7 4.6 7.7 0.1 3.0 2 2 1 3 3 3 0 Kinesin motor Syntaxin_2 PF14523.1 CAR24373.1 - 0.1 12.6 8.8 1.1 9.3 0.4 3.2 1 1 1 2 2 2 0 Syntaxin-like protein YlqD PF11068.3 CAR24373.1 - 0.26 11.3 2.4 0.31 11.0 0.3 2.0 2 0 0 2 2 2 0 YlqD protein DUF1664 PF07889.7 CAR24373.1 - 0.33 10.7 4.3 7.5 6.3 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlgN PF05130.7 CAR24373.1 - 4.5 7.5 11.9 0.29 11.3 0.2 2.8 1 1 2 3 3 3 0 FlgN protein Synaptonemal_3 PF15191.1 CAR24373.1 - 5.2 6.8 11.4 2.4 7.9 0.3 3.5 1 1 2 3 3 3 0 Synaptonemal complex central element protein 3 DUF3639 PF12341.3 CAR24374.1 - 1.4e-10 40.9 0.1 3.3e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) DNA_pol_alpha_N PF12254.3 CAR24374.1 - 0.027 14.3 5.3 0.085 12.6 3.6 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal WD40 PF00400.27 CAR24374.1 - 0.039 13.8 1.9 9.8 6.2 0.0 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat WD40 PF00400.27 CAR24375.1 - 2.1e-26 90.8 0.2 8.1e-07 28.6 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CAR24375.1 - 0.047 11.9 0.1 0.43 8.8 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Ammonium_transp PF00909.16 CAR24376.1 - 2.5e-116 388.4 22.3 2.9e-116 388.2 15.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ABC2_membrane_2 PF12679.2 CAR24376.1 - 0.06 12.1 1.3 0.16 10.8 0.9 1.8 1 0 0 1 1 1 0 ABC-2 family transporter protein BRO1 PF03097.13 CAR24377.1 - 0.0022 16.7 0.0 0.0063 15.3 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain Acyltransferase PF01553.16 CAR24378.1 - 5.6e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 CAR24379.1 - 1e-12 47.6 0.0 2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF3256 PF11644.3 CAR24379.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) TCL1_MTCP1 PF01840.12 CAR24379.1 - 0.27 10.7 2.9 6.4 6.3 0.1 2.7 2 1 1 3 3 3 0 TCL1/MTCP1 family Kinesin PF00225.18 CAR24380.1 - 7e-99 330.6 3.8 1.4e-98 329.7 2.7 1.5 1 0 0 1 1 1 1 Kinesin motor domain Ribosomal_L29 PF00831.18 CAR24380.1 - 0.0044 16.6 1.9 0.0044 16.6 1.3 3.9 4 0 0 4 4 4 1 Ribosomal L29 protein Spore_II_R PF09551.5 CAR24380.1 - 3.2 7.7 9.1 0.15 12.0 0.1 3.2 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) DUF1664 PF07889.7 CAR24380.1 - 5.6 6.7 11.3 0.36 10.6 1.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Rrp15p PF07890.7 CAR24381.1 - 3.8e-32 111.0 14.7 3.8e-32 111.0 10.2 2.5 2 1 0 2 2 2 1 Rrp15p TMEM51 PF15345.1 CAR24381.1 - 0.78 9.3 7.9 1.4 8.5 5.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Metallophos PF00149.23 CAR24382.1 - 1.5e-37 128.9 0.1 2.4e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CAR24382.1 - 2.3e-21 75.2 0.1 1.1e-18 66.6 0.1 2.8 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAR24382.1 - 1.4e-18 65.6 1.0 1.3e-07 30.9 0.5 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR24382.1 - 1.3e-14 52.8 0.2 5.6e-05 22.7 0.3 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 CAR24382.1 - 1.5e-09 37.7 0.3 6.6e-07 29.2 0.2 2.8 1 1 0 1 1 1 1 PPP5 TPR repeat region TPR_9 PF13371.1 CAR24382.1 - 6.4e-06 25.9 0.0 0.00011 21.9 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAR24382.1 - 2.6e-05 23.6 3.6 0.0088 15.7 0.3 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR24382.1 - 0.00067 19.6 0.1 0.69 10.2 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR24382.1 - 0.00098 18.9 0.7 0.15 11.9 0.0 3.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 CAR24382.1 - 0.0011 19.2 0.1 0.67 10.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR24382.1 - 0.0027 17.5 0.1 0.43 10.5 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat NBP1 PF08537.5 CAR24382.1 - 0.0081 15.4 0.2 0.012 14.7 0.2 1.2 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 TPR_16 PF13432.1 CAR24382.1 - 0.017 15.8 0.0 0.44 11.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAR24382.1 - 0.14 12.0 0.0 0.61 10.0 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.13 CAR24382.1 - 0.25 11.2 1.6 0.59 10.0 0.8 1.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain CBF PF03914.12 CAR24383.1 - 6.6e-48 162.2 1.0 1.6e-47 161.0 0.7 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Asn_synthase PF00733.16 CAR24384.1 - 1.3e-70 237.8 0.1 1.8e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CAR24384.1 - 5.9e-36 122.9 0.0 9.6e-36 122.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CAR24384.1 - 8.8e-30 103.3 0.0 2.8e-29 101.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CAR24384.1 - 5.4e-07 29.0 0.0 9.6e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 CAR24384.1 - 0.001 17.8 0.0 0.32 9.6 0.0 2.9 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 CAR24384.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Sulfate_transp PF00916.15 CAR24386.1 - 3.8e-48 163.9 7.4 3.8e-48 163.9 5.1 1.6 2 0 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 CAR24386.1 - 7.2e-13 47.9 1.3 1.6e-12 46.9 0.9 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 CAR24386.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MCLC PF05934.6 CAR24387.1 - 0.73 8.0 3.9 1.5 7.0 0.1 2.0 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) NRDE PF05742.7 CAR24388.1 - 1.1e-46 159.3 0.0 1.3e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 NRDE protein HAUS4 PF14735.1 CAR24388.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF2305 PF10230.4 CAR24389.1 - 2e-71 240.5 0.1 2.3e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CAR24389.1 - 8.5e-08 32.3 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 CAR24389.1 - 0.00051 18.9 0.0 0.063 12.0 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.2 CAR24389.1 - 0.00085 19.0 0.0 0.0011 18.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CAR24389.1 - 0.0017 17.9 0.7 0.0028 17.2 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 CAR24389.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CAR24389.1 - 0.0092 15.5 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Lipase_2 PF01674.13 CAR24389.1 - 0.01 15.1 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 2) Thioesterase PF00975.15 CAR24389.1 - 0.027 14.7 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF1749 PF08538.5 CAR24389.1 - 0.044 12.6 0.2 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.8 CAR24389.1 - 0.06 12.9 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase DUF2235 PF09994.4 CAR24389.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Utp8 PF10395.4 CAR24390.1 - 4.2e-199 663.1 19.8 4.7e-199 663.0 13.8 1.0 1 0 0 1 1 1 1 Utp8 family SYF2 PF08231.7 CAR24391.1 - 4.7e-10 39.7 15.8 4.7e-10 39.7 11.0 1.7 1 1 1 2 2 2 1 SYF2 splicing factor Transketolase_C PF02780.15 CAR24391.1 - 0.096 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain DUF1804 PF08822.6 CAR24391.1 - 0.73 9.5 5.9 0.13 11.9 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) ExbD PF02472.11 CAR24391.1 - 4.6 7.2 7.2 1.4e+02 2.4 5.0 2.6 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR BAR_2 PF10455.4 CAR24392.1 - 4.9e-99 330.8 19.6 7.5e-99 330.2 13.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Herpes_UL6 PF01763.11 CAR24392.1 - 0.016 13.3 6.9 0.028 12.6 4.8 1.5 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3610 PF12272.3 CAR24392.1 - 0.084 12.5 6.4 6.2 6.4 0.1 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3610) Baculo_PEP_C PF04513.7 CAR24392.1 - 0.32 10.8 3.8 1.7 8.4 0.2 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Virulence_fact PF13769.1 CAR24392.1 - 1.9 8.3 6.3 0.24 11.3 0.3 2.5 2 1 0 2 2 2 0 Virulence factor HTH_Tnp_Mu_1 PF02316.11 CAR24392.1 - 5.8 6.6 7.7 0.71 9.5 0.6 2.7 3 0 0 3 3 3 0 Mu DNA-binding domain RepA_C PF04796.7 CAR24393.1 - 8.3 5.9 7.0 1.2 8.7 0.3 2.8 2 1 1 3 3 3 0 Plasmid encoded RepA protein MARVEL PF01284.18 CAR24394.1 - 4.2e-29 101.2 13.0 5.8e-29 100.7 9.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain 7TM-7TMR_HD PF07698.6 CAR24394.1 - 0.21 11.0 10.8 0.034 13.5 3.7 1.9 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Band_7 PF01145.20 CAR24395.1 - 2.1e-23 83.1 5.7 2.6e-23 82.8 3.6 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 CAR24395.1 - 0.022 14.1 1.0 0.038 13.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) UQ_con PF00179.21 CAR24396.1 - 1.6e-34 118.3 0.0 1.8e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAR24396.1 - 0.0064 16.3 0.0 0.0072 16.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 CAR24396.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 CAR24396.1 - 0.021 14.5 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Ribonuc_L-PSP PF01042.16 CAR24397.1 - 4.1e-25 87.8 0.0 5.2e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pet20 PF08692.5 CAR24398.1 - 5.8e-45 152.6 0.1 8.5e-45 152.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Ribosomal_60s PF00428.14 CAR24398.1 - 0.58 10.5 4.5 0.95 9.9 3.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Actin PF00022.14 CAR24399.1 - 6.1e-23 80.8 0.0 1.5e-16 59.8 0.0 3.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CAR24399.1 - 1.1e-05 24.2 0.0 0.00017 20.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CAR24399.1 - 0.059 13.2 0.4 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Cell division protein FtsA HSF_DNA-bind PF00447.12 CAR24400.1 - 1.1e-35 121.9 0.3 1.1e-35 121.9 0.2 2.9 3 0 0 3 3 3 1 HSF-type DNA-binding Trypan_PARP PF05887.6 CAR24400.1 - 6.9 6.4 15.9 0.16 11.7 5.1 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) UBA PF00627.26 CAR24401.1 - 2.1e-09 36.9 0.1 4.9e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CAR24401.1 - 0.0023 17.4 0.0 0.012 15.1 0.0 2.4 1 0 0 1 1 1 1 UBA-like domain HBS1_N PF08938.5 CAR24401.1 - 0.006 16.6 0.0 0.19 11.8 0.0 3.1 3 0 0 3 3 3 1 HBS1 N-terminus CUE PF02845.11 CAR24401.1 - 0.035 13.5 0.1 0.23 10.9 0.1 2.5 1 1 0 1 1 1 0 CUE domain DUF2666 PF10869.3 CAR24401.1 - 0.12 12.4 0.3 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Metallophos PF00149.23 CAR24402.1 - 5e-07 29.3 0.0 1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR24402.1 - 0.00044 20.1 0.0 0.0055 16.5 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Iso_dh PF00180.15 CAR24403.1 - 1.4e-102 343.2 0.0 1.7e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ThiF PF00899.16 CAR24404.1 - 1.1e-35 122.4 0.0 2.6e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CAR24404.1 - 1.1e-24 85.7 0.1 3.1e-24 84.3 0.1 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CAR24404.1 - 4.4e-20 70.7 3.9 4.4e-20 70.7 2.7 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CAR24404.1 - 7.4e-07 29.1 1.0 2.8e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 CAR24404.1 - 0.00043 20.3 0.6 0.0014 18.6 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CAR24404.1 - 0.01 16.0 0.0 0.14 12.4 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Thioredoxin_8 PF13905.1 CAR24404.1 - 0.042 13.9 0.4 0.11 12.6 0.3 1.6 1 0 0 1 1 1 0 Thioredoxin-like RhoGAP PF00620.22 CAR24405.1 - 2e-34 118.4 0.8 5.2e-34 117.0 0.5 1.7 1 1 0 1 1 1 1 RhoGAP domain BAR PF03114.13 CAR24406.1 - 3.2e-59 200.2 8.1 4.4e-59 199.7 5.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CAR24406.1 - 7.3e-15 54.0 0.1 1.6e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR24406.1 - 1.2e-13 50.4 0.3 2.1e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR24406.1 - 2.3e-08 33.3 0.0 4.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Sugar_tr PF00083.19 CAR24407.1 - 3.4e-91 306.0 22.2 1.8e-47 161.9 3.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CAR24407.1 - 1.7e-26 92.7 23.6 1.7e-26 92.7 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CAR24407.1 - 4.1 5.4 16.4 0.044 11.8 3.9 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector ERCC4 PF02732.10 CAR24408.1 - 2.6e-26 92.0 0.4 4.9e-26 91.1 0.3 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 CAR24408.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain GTP_EFTU PF00009.22 CAR24409.1 - 5.6e-63 211.7 0.2 7.8e-63 211.3 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CAR24409.1 - 3.1e-37 126.7 0.1 1e-36 125.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CAR24409.1 - 3e-21 75.0 0.0 7.7e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CAR24409.1 - 3.4e-13 49.2 0.0 9.7e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CAR24409.1 - 8.6e-13 48.2 1.1 2.8e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR24409.1 - 6.5e-06 26.0 0.3 1.3e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR24409.1 - 0.04 14.4 0.2 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 Miro-like protein PX PF00787.19 CAR24410.1 - 2.1e-08 33.9 0.2 4.3e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CAR24410.1 - 2.6e-06 26.8 8.9 3.9e-06 26.2 6.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like HAD_2 PF13419.1 CAR24411.1 - 7.8e-15 55.5 0.0 1.5e-13 51.3 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR24411.1 - 5.7e-12 46.5 0.0 1.4e-08 35.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CAR24411.1 - 8.4e-11 41.4 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CAR24411.1 - 4.7e-05 23.6 0.0 8.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAR24411.1 - 0.023 14.2 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CAR24411.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Grp1_Fun34_YaaH PF01184.14 CAR24413.1 - 9.8e-77 256.9 16.5 1.1e-76 256.7 11.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2344 PF10105.4 CAR24413.1 - 0.0073 15.8 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) FTA4 PF13093.1 CAR24415.1 - 0.00012 21.6 1.8 0.00016 21.1 1.2 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ribosomal_60s PF00428.14 CAR24416.1 - 5.8e-25 87.5 16.6 6.7e-25 87.3 11.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mito_carr PF00153.22 CAR24417.1 - 3e-62 206.3 2.7 2.2e-20 72.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF718 PF05336.8 CAR24417.1 - 0.041 13.6 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF718) Tim17 PF02466.14 CAR24417.1 - 0.21 11.6 2.6 1.2 9.1 0.1 2.6 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.22 CAR24418.1 - 1.9e-50 168.5 3.7 1.2e-17 63.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_2 PF13347.1 CAR24418.1 - 0.00057 18.4 1.7 0.37 9.1 0.1 2.1 1 1 0 2 2 2 2 MFS/sugar transport protein DUF2620 PF10941.3 CAR24418.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DUF3366 PF11846.3 CAR24419.1 - 0.082 12.7 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) RRM_1 PF00076.17 CAR24420.1 - 2.3e-12 46.3 0.0 5.4e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24420.1 - 1.6e-10 40.8 0.0 2.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24420.1 - 6.1e-05 22.7 0.0 9.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR24420.1 - 0.0083 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FoP_duplication PF13865.1 CAR24420.1 - 0.0086 16.5 2.6 0.0086 16.5 1.8 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Enterotoxin_b PF01376.13 CAR24420.1 - 0.036 13.9 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain Afi1 PF07792.7 CAR24421.1 - 1.3e-44 151.7 1.1 9e-44 148.9 0.0 2.3 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CAR24421.1 - 1.5e-32 111.5 0.1 4.4e-32 110.1 0.1 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis TPP_enzyme_N PF02776.13 CAR24422.1 - 1.5e-27 96.1 0.0 2.6e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR24422.1 - 1.6e-15 57.0 0.0 3.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CAR24422.1 - 3.2e-12 46.2 0.0 7.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AIRC PF00731.15 CAR24423.1 - 7.1e-65 216.8 0.7 1.3e-64 216.0 0.5 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 CAR24423.1 - 8.6e-64 214.0 0.0 1.5e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CAR24423.1 - 2.8e-08 33.7 0.0 5.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 CAR24423.1 - 9.2e-05 21.6 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.12 CAR24423.1 - 0.00067 19.0 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 CAR24423.1 - 0.0048 16.2 0.0 0.055 12.8 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus F420_oxidored PF03807.12 CAR24423.1 - 0.021 15.2 0.1 0.076 13.4 0.0 2.1 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 CAR24423.1 - 0.029 14.6 0.0 0.82 9.9 0.0 2.6 2 1 1 3 3 3 0 XdhC Rossmann domain ATPgrasp_Ter PF15632.1 CAR24423.1 - 0.031 13.0 0.0 0.83 8.3 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon NPV_P10 PF05531.7 CAR24423.1 - 0.035 14.3 0.2 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ATP-grasp_3 PF02655.9 CAR24423.1 - 0.072 12.9 0.0 0.75 9.6 0.0 2.5 2 1 0 2 2 2 0 ATP-grasp domain Shikimate_DH PF01488.15 CAR24423.1 - 0.087 12.9 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 CAR24423.1 - 0.11 12.4 0.0 0.42 10.6 0.0 2.0 1 1 1 2 2 2 0 TrkA-N domain Glyco_transf_21 PF13506.1 CAR24424.1 - 4.3e-17 61.9 0.0 8.8e-12 44.6 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 CAR24424.1 - 1.5e-14 54.3 0.0 6.3e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CAR24424.1 - 3.8e-05 23.4 0.0 0.00014 21.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Complex1_LYR PF05347.10 CAR24425.1 - 1.9e-16 59.6 1.0 2.2e-16 59.4 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CAR24425.1 - 3.1e-14 52.9 0.6 3.6e-14 52.7 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Topoisom_I_N PF02919.10 CAR24425.1 - 0.023 14.0 0.0 0.023 14.0 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RhoGAP PF00620.22 CAR24426.1 - 7.1e-42 142.5 0.5 7.1e-42 142.5 0.4 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CAR24426.1 - 1.3e-11 44.3 25.5 1.2e-05 25.2 8.0 2.6 2 0 0 2 2 2 2 LIM domain Macoilin PF09726.4 CAR24426.1 - 0.00048 18.5 15.9 0.00048 18.5 11.0 2.2 2 0 0 2 2 2 1 Transmembrane protein DivIC PF04977.10 CAR24426.1 - 0.024 14.1 2.0 0.076 12.5 1.4 1.8 1 0 0 1 1 1 0 Septum formation initiator Seryl_tRNA_N PF02403.17 CAR24426.1 - 0.15 12.1 12.5 0.029 14.3 3.2 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 CAR24426.1 - 0.37 8.6 4.2 0.6 7.9 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LSM PF01423.17 CAR24427.1 - 4.9e-17 61.2 0.1 5.7e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAR24427.1 - 1.5e-06 28.0 0.1 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain F1F0-ATPsyn_F PF10791.4 CAR24428.1 - 7.9e-42 141.4 0.3 8.8e-42 141.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Pyr_redox_3 PF13738.1 CAR24429.1 - 5.8e-06 26.5 0.0 0.005 16.9 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR24429.1 - 0.00083 19.3 0.0 0.0029 17.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CAR24429.1 - 0.003 17.3 0.0 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CAR24429.1 - 0.049 13.5 0.0 0.097 12.5 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lipase_GDSL PF00657.17 CAR24430.1 - 3.7e-21 76.0 0.0 4.4e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CAR24430.1 - 5.2e-19 69.0 0.0 6.5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BCS1_N PF08740.6 CAR24432.1 - 1.5e-47 161.6 0.0 2.4e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CAR24432.1 - 1.9e-23 83.1 0.0 3.5e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR24432.1 - 2.8e-06 28.1 0.0 7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR24432.1 - 0.00051 20.3 0.0 0.0021 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR24432.1 - 0.00054 19.0 0.0 0.00088 18.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CAR24432.1 - 0.00089 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CAR24432.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CAR24432.1 - 0.0014 18.3 0.0 0.0038 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAR24432.1 - 0.0014 18.7 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CAR24432.1 - 0.0021 18.1 0.1 0.0036 17.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR24432.1 - 0.0029 17.5 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CAR24432.1 - 0.0041 16.5 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAR24432.1 - 0.0052 16.6 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR24432.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 CAR24432.1 - 0.013 15.0 0.0 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CAR24432.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CAR24432.1 - 0.019 14.5 0.0 0.075 12.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain KaiC PF06745.8 CAR24432.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 CAR24432.1 - 0.034 14.3 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 CAR24432.1 - 0.035 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 CAR24432.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.6 1 1 0 1 1 1 0 Part of AAA domain Miro PF08477.8 CAR24432.1 - 0.048 14.1 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 CAR24432.1 - 0.092 12.3 0.0 0.26 10.9 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.1 CAR24432.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CAR24432.1 - 0.1 12.2 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CAR24432.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Gram_pos_anchor PF00746.16 CAR24432.1 - 0.11 12.3 1.0 0.24 11.2 0.7 1.6 1 0 0 1 1 1 0 Gram positive anchor Rad17 PF03215.10 CAR24432.1 - 0.11 11.1 0.0 0.22 10.1 0.0 1.4 1 1 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 CAR24432.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CAR24432.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase YTH PF04146.10 CAR24433.1 - 3.2e-41 140.1 0.1 4.6e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain PH_11 PF15413.1 CAR24433.1 - 0.071 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain COQ7 PF03232.8 CAR24434.1 - 3.9e-76 254.3 0.0 4.6e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Sds3 PF08598.6 CAR24434.1 - 0.03 13.8 0.6 0.056 12.9 0.4 1.3 1 0 0 1 1 1 0 Sds3-like EF-hand_1 PF00036.27 CAR24435.1 - 8.7e-26 87.2 1.9 2.8e-07 29.3 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CAR24435.1 - 6e-23 78.6 0.2 1.6e-05 24.3 0.0 4.8 5 0 0 5 5 4 4 EF-hand domain EF-hand_7 PF13499.1 CAR24435.1 - 9.4e-22 76.9 1.6 5.1e-13 48.9 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CAR24435.1 - 3.2e-19 67.3 3.8 5.2e-07 28.7 0.2 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CAR24435.1 - 1.5e-16 59.7 4.0 1.9e-08 33.8 0.1 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CAR24435.1 - 9.9e-06 25.2 1.7 0.87 9.3 0.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CAR24435.1 - 5e-05 23.3 0.5 0.12 12.3 0.1 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CAR24435.1 - 6.9e-05 22.6 0.1 0.0083 16.0 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain S10_plectin PF03501.10 CAR24435.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_2 PF09068.6 CAR24435.1 - 0.0067 16.5 0.0 2.2 8.3 0.0 2.6 2 1 0 2 2 2 1 EF hand PMBR PF09373.5 CAR24435.1 - 0.018 14.9 0.4 48 4.1 0.0 4.0 4 0 0 4 4 4 0 Pseudomurein-binding repeat SHOCT PF09851.4 CAR24435.1 - 0.026 14.0 3.7 3.2 7.3 0.1 2.6 2 0 0 2 2 2 0 Short C-terminal domain EF-hand_10 PF14788.1 CAR24435.1 - 0.1 12.2 1.5 28 4.4 0.1 3.5 4 0 0 4 4 4 0 EF hand UCH PF00443.24 CAR24438.1 - 2.4e-61 207.2 1.8 1.7e-60 204.4 0.3 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CAR24438.1 - 1.8e-48 161.8 6.2 4.6e-19 67.5 0.0 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 CAR24438.1 - 3.1e-10 40.0 3.0 0.00013 21.5 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF4090 PF13319.1 CAR24438.1 - 0.079 12.9 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) GPP34 PF05719.6 CAR24439.1 - 2.8e-63 213.7 0.0 3.5e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.23 CAR24440.1 - 4.8e-73 246.5 2.7 2.4e-64 217.9 0.5 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Leo1 PF04004.8 CAR24441.1 - 1.1e-45 155.3 0.9 1.1e-45 155.3 0.6 2.2 2 0 0 2 2 2 1 Leo1-like protein Profilin PF00235.14 CAR24442.1 - 1.9e-39 134.5 0.0 2.1e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Profilin YCII PF03795.9 CAR24443.1 - 1.1e-06 28.6 0.0 1.3e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain RAI1 PF08652.6 CAR24444.1 - 4.4e-07 29.5 0.0 1.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Mor PF08765.6 CAR24444.1 - 0.03 14.1 0.1 0.056 13.2 0.1 1.4 1 0 0 1 1 1 0 Mor transcription activator family Bac_surface_Ag PF01103.18 CAR24445.1 - 4.3e-25 88.8 4.2 6.5e-25 88.2 2.9 1.3 1 1 0 1 1 1 1 Surface antigen FHA PF00498.21 CAR24446.1 - 0.00023 21.1 0.3 0.0024 17.9 0.0 2.7 3 0 0 3 3 3 1 FHA domain Aldo_ket_red PF00248.16 CAR24447.1 - 6.4e-46 156.4 0.0 7.9e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kei1 PF08552.6 CAR24448.1 - 1.1e-44 152.3 6.4 1.3e-44 152.1 4.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF3611 PF12263.3 CAR24448.1 - 1.4 8.2 10.2 1.3 8.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) RIO1 PF01163.17 CAR24449.1 - 1.1e-71 240.1 0.9 1.1e-71 240.1 0.6 2.5 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 CAR24449.1 - 0.022 14.4 0.0 0.38 10.4 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family YL1 PF05764.8 CAR24449.1 - 0.17 11.4 25.1 0.42 10.1 17.4 1.7 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 CAR24449.1 - 1.5 6.7 21.9 2.6 5.9 15.2 1.3 1 0 0 1 1 1 0 CDC45-like protein TLD PF07534.11 CAR24450.1 - 1.2e-25 90.1 0.0 4.3e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 TLD NRN1 PF15056.1 CAR24450.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Neuritin protein family NUC153 PF08159.7 CAR24451.1 - 8.5e-15 54.0 1.5 8.5e-15 54.0 1.0 3.4 3 1 0 3 3 3 1 NUC153 domain YjgP_YjgQ PF03739.9 CAR24451.1 - 8.6 4.9 4.9 17 4.0 0.0 2.3 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family WD40 PF00400.27 CAR24452.1 - 3.7e-33 112.1 5.1 6.6e-07 28.9 0.0 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CAR24452.1 - 0.0098 14.0 0.1 0.024 12.7 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 AAA PF00004.24 CAR24453.1 - 4.7e-41 140.0 0.1 1.2e-40 138.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CAR24453.1 - 2e-05 24.5 0.2 0.00017 21.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CAR24453.1 - 3.3e-05 23.9 0.4 0.011 15.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CAR24453.1 - 0.00013 21.7 1.5 0.00043 20.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAR24453.1 - 0.00066 19.8 1.4 0.0068 16.5 0.1 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CAR24453.1 - 0.00078 18.5 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CAR24453.1 - 0.0031 16.7 0.2 0.016 14.4 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 CAR24453.1 - 0.0041 16.0 0.0 0.0083 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CAR24453.1 - 0.0042 16.9 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CAR24453.1 - 0.0089 15.2 0.2 0.028 13.5 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CAR24453.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CAR24453.1 - 0.011 15.4 0.2 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 CAR24453.1 - 0.013 16.2 0.2 0.044 14.6 0.0 2.0 2 1 0 2 2 1 0 AAA domain BLOC1_2 PF10046.4 CAR24453.1 - 0.022 14.8 1.5 0.081 13.0 1.1 2.0 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_25 PF13481.1 CAR24453.1 - 0.027 13.8 0.5 0.21 11.0 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 CAR24453.1 - 0.033 14.0 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CAR24453.1 - 0.041 13.4 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CAR24453.1 - 0.045 12.8 0.1 0.1 11.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 CAR24453.1 - 0.053 13.0 1.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CAR24453.1 - 0.1 11.6 1.1 0.27 10.3 0.0 2.2 3 0 0 3 3 3 0 KaiC DUF2730 PF10805.3 CAR24453.1 - 0.16 11.6 1.9 1.6 8.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) RNA_pol_Rpb1_5 PF04998.12 CAR24454.1 - 2e-94 315.9 0.1 3.6e-94 315.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CAR24454.1 - 1.1e-83 281.3 0.0 1.7e-83 280.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CAR24454.1 - 4.5e-70 234.8 0.0 8.6e-70 233.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CAR24454.1 - 1.1e-37 129.2 0.0 2.9e-37 127.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CAR24454.1 - 2.1e-31 107.8 0.0 5.1e-31 106.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rad60-SLD PF11976.3 CAR24455.1 - 1.5e-19 69.4 0.6 1.5e-19 69.4 0.4 3.4 3 1 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CAR24455.1 - 1.9e-06 27.1 2.7 4.1e-06 26.1 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin family DUF4092 PF13322.1 CAR24455.1 - 0.0093 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4092) Rhamno_transf PF11316.3 CAR24455.1 - 0.024 13.8 0.2 0.052 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase Peptidase_M18 PF02127.10 CAR24456.1 - 1.3e-171 570.9 0.0 1.5e-171 570.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CAR24456.1 - 5.4e-09 35.2 0.0 3e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase SAF_2 PF13144.1 CAR24456.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 SAF-like WD40 PF00400.27 CAR24457.1 - 1.2e-07 31.3 0.1 0.019 14.8 0.0 5.0 4 1 1 5 5 5 2 WD domain, G-beta repeat ThiF PF00899.16 CAR24458.1 - 6.1e-41 139.4 0.0 1.1e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CAR24458.1 - 3.7e-24 84.1 0.1 6.9e-24 83.2 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CAR24458.1 - 2.6e-09 37.4 0.0 4.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 CAR24458.1 - 0.0004 20.4 0.0 0.0023 18.0 0.0 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CAR24458.1 - 0.056 13.7 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding EMP24_GP25L PF01105.19 CAR24459.1 - 6.7e-32 110.6 0.5 7.8e-32 110.4 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 CAR24459.1 - 0.064 13.6 0.3 0.16 12.4 0.2 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BCIP PF13862.1 CAR24461.1 - 2e-49 167.7 0.8 2.7e-49 167.3 0.5 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PAXIP1_C PF15364.1 CAR24461.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein HSA PF07529.8 CAR24462.1 - 9.2e-15 54.2 0.0 9.2e-15 54.2 0.0 3.0 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 CAR24462.1 - 1.2e-08 34.9 0.6 3.5e-08 33.4 0.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain VHS PF00790.14 CAR24463.1 - 6.3e-45 152.2 0.1 2.7e-44 150.2 0.0 1.9 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 CAR24463.1 - 1.5e-22 80.0 0.2 3e-22 79.0 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 CAR24463.1 - 6.8e-13 48.4 2.0 1.6e-12 47.2 1.4 1.6 1 0 0 1 1 1 1 GAT domain DUF1219 PF06755.7 CAR24463.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1219) SAC3_GANP PF03399.11 CAR24463.1 - 0.14 11.7 1.1 2.2 7.8 0.5 2.3 1 1 0 2 2 2 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2365 PF10157.4 CAR24464.1 - 0.00077 19.3 0.3 0.00098 19.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) UPF0184 PF03670.8 CAR24464.1 - 0.037 14.1 2.5 0.087 13.0 0.3 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Dysbindin PF04440.11 CAR24464.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) DUF948 PF06103.6 CAR24464.1 - 0.13 12.1 1.0 17 5.3 0.2 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 CAR24465.1 - 0.0028 17.4 14.2 0.0028 17.4 9.9 10.3 6 3 2 9 9 9 3 TATA element modulatory factor 1 DNA binding WD40_alt PF14077.1 CAR24465.1 - 0.0031 17.0 9.7 0.083 12.5 0.8 3.9 3 0 0 3 3 3 2 Alternative WD40 repeat motif Tropomyosin_1 PF12718.2 CAR24465.1 - 0.0068 16.2 22.8 0.0068 16.2 15.8 7.4 1 1 6 8 8 8 1 Tropomyosin like Glycos_transf_3 PF00591.16 CAR24466.1 - 7.5e-81 271.2 0.0 9.1e-81 270.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CAR24466.1 - 1e-09 37.7 0.0 2.1e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Septin PF00735.13 CAR24467.1 - 4.4e-115 383.5 0.0 6.3e-115 383.0 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CAR24467.1 - 6.1e-06 26.1 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CAR24467.1 - 5.1e-05 22.5 0.1 0.00016 20.8 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CAR24467.1 - 0.00038 19.9 0.1 0.00098 18.6 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 CAR24467.1 - 0.00048 20.2 0.0 0.0013 18.8 0.0 2.0 2 1 0 2 2 1 1 AAA domain GTP_EFTU PF00009.22 CAR24467.1 - 0.00091 18.7 0.4 0.0061 16.0 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CAR24467.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CAR24467.1 - 0.0047 17.4 0.0 0.016 15.6 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 CAR24467.1 - 0.0056 16.5 4.6 2.1 8.1 0.0 3.2 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.11 CAR24467.1 - 0.0074 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family NACHT PF05729.7 CAR24467.1 - 0.012 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CAR24467.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 CAR24467.1 - 0.026 14.5 0.0 0.071 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain IIGP PF05049.8 CAR24467.1 - 0.027 13.2 0.2 0.09 11.5 0.1 1.9 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 CAR24467.1 - 0.034 13.5 0.0 0.071 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 CAR24467.1 - 0.044 14.0 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Pox_A32 PF04665.7 CAR24467.1 - 0.072 12.3 0.2 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 CAR24467.1 - 0.084 12.7 0.7 0.23 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CAR24467.1 - 0.14 11.6 0.2 0.84 9.1 0.1 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pyr_redox_2 PF07992.9 CAR24468.1 - 1.5e-28 100.0 0.0 1.8e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR24468.1 - 4.6e-18 65.4 0.1 2.9e-15 56.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR24468.1 - 3.9e-10 40.1 0.0 7e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CAR24468.1 - 0.00021 20.2 0.7 1.2 7.9 0.1 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CAR24468.1 - 0.00045 20.1 0.0 0.041 13.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 CAR24468.1 - 0.0017 18.5 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 CAR24468.1 - 0.0025 16.9 0.0 0.013 14.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 CAR24468.1 - 0.0029 16.5 0.0 7.5 5.3 0.0 3.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 CAR24468.1 - 0.0041 16.0 0.7 0.74 8.5 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Shikimate_DH PF01488.15 CAR24468.1 - 0.027 14.5 0.0 7.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 CAR24468.1 - 0.035 13.0 0.4 14 4.4 0.0 3.1 2 1 1 4 4 4 0 FAD dependent oxidoreductase PX PF00787.19 CAR24469.1 - 1.7e-15 56.7 0.0 2.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 PX domain Aldo_ket_red PF00248.16 CAR24470.1 - 8.8e-55 185.5 0.0 1e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.9 CAR24471.1 - 4.8e-35 118.9 7.7 2.4e-18 65.4 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 CAR24471.1 - 0.0061 16.3 5.4 0.26 11.1 0.1 3.4 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange Exo_endo_phos_2 PF14529.1 CAR24472.1 - 0.03 13.9 1.4 0.11 12.1 0.3 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Pkinase PF00069.20 CAR24473.1 - 1.1e-69 234.4 0.0 1.6e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24473.1 - 2.7e-51 174.1 0.0 4.1e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR24473.1 - 6.6e-07 28.5 0.0 2e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAR24473.1 - 0.016 14.9 0.0 0.19 11.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rep_fac_C PF08542.6 CAR24474.1 - 0.062 13.2 0.2 1.6 8.7 0.0 3.1 4 0 0 4 4 4 0 Replication factor C C-terminal domain ATP-synt_S1 PF05827.7 CAR24475.1 - 2.6e-34 118.8 0.6 3.1e-34 118.5 0.4 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) SNARE PF05739.14 CAR24476.1 - 1.6e-18 66.1 2.5 1.6e-18 66.1 1.7 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 CAR24476.1 - 7.7e-17 61.1 8.8 7.7e-17 61.1 6.1 2.5 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.20 CAR24476.1 - 0.0017 18.4 0.2 0.0017 18.4 0.1 3.5 1 1 1 2 2 2 1 Syntaxin DUF4319 PF14203.1 CAR24476.1 - 0.011 15.2 0.2 0.087 12.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) Synaptobrevin PF00957.16 CAR24476.1 - 0.028 13.9 0.6 0.028 13.9 0.4 3.2 3 0 0 3 3 3 0 Synaptobrevin FdhE PF04216.7 CAR24476.1 - 0.066 12.9 4.3 0.76 9.4 0.0 2.2 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation Sulfotransfer_2 PF03567.9 CAR24476.1 - 0.081 12.5 3.6 0.13 11.8 2.5 1.3 1 0 0 1 1 1 0 Sulfotransferase family HsbA PF12296.3 CAR24476.1 - 1.5 8.7 7.0 3.7 7.4 0.7 2.8 2 1 0 2 2 2 0 Hydrophobic surface binding protein A PBP_sp32 PF07222.7 CAR24476.1 - 2.6 7.1 8.9 4.5 6.3 6.2 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 WD40 PF00400.27 CAR24477.1 - 4.5e-55 181.6 31.4 3.7e-11 42.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CAR24477.1 - 0.0054 16.4 5.1 0.16 11.6 0.1 3.3 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term BBS2_Mid PF14783.1 CAR24477.1 - 0.68 9.7 4.6 2.8 7.7 0.2 3.8 4 2 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region FAD_binding_6 PF00970.19 CAR24478.1 - 2.1e-05 24.5 0.0 0.00015 21.8 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CAR24478.1 - 0.0087 16.6 0.0 0.022 15.3 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain tRNA-synt_1b PF00579.20 CAR24479.1 - 7.9e-76 254.9 0.0 1e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2486 PF10667.4 CAR24479.1 - 0.073 13.6 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Hira PF07569.6 CAR24480.1 - 1.5e-83 279.3 0.1 5.3e-83 277.5 0.1 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 CAR24480.1 - 5.7e-05 22.8 5.2 7.5 6.6 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CK_II_beta PF01214.13 CAR24481.1 - 1.2e-72 243.2 0.0 1.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit E1-E2_ATPase PF00122.15 CAR24482.1 - 8e-52 175.5 0.0 1.8e-51 174.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 CAR24482.1 - 6.8e-42 141.4 8.2 4.6e-13 49.1 0.0 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.21 CAR24482.1 - 4.7e-40 138.3 0.0 8.3e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR24482.1 - 4.9e-17 62.7 0.0 9.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAR24482.1 - 8.2e-08 32.1 0.1 0.0017 17.9 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase GFA PF04828.9 CAR24482.1 - 0.023 14.6 1.3 4.6 7.2 0.0 3.2 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF3133 PF11331.3 CAR24482.1 - 0.13 11.8 2.8 18 4.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) DUF4502 PF14950.1 CAR24482.1 - 0.21 10.7 1.4 1.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4502) DUF164 PF02591.10 CAR24482.1 - 0.48 10.3 6.7 1 9.2 0.2 2.8 3 0 0 3 3 3 0 Putative zinc ribbon domain Lactamase_B PF00753.22 CAR24483.1 - 5.4e-21 75.1 0.6 1.3e-20 73.8 0.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CAR24483.1 - 4.4e-06 26.3 0.0 7.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CAR24483.1 - 0.005 16.5 0.1 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CUE PF02845.11 CAR24484.1 - 6.7e-09 35.0 0.0 1.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain RAI1 PF08652.6 CAR24485.1 - 0.039 13.7 0.3 0.23 11.2 0.1 2.3 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease TOMM6 PF15184.1 CAR24488.1 - 0.00069 18.8 0.0 0.00087 18.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit TOM6 homolog DEAD PF00270.24 CAR24489.1 - 5.5e-36 123.6 0.3 2.6e-34 118.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR24489.1 - 7.2e-27 93.0 0.1 1.3e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR24489.1 - 8.1e-05 22.5 0.5 0.00019 21.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 CAR24489.1 - 0.03 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Helicase_C_2 PF13307.1 CAR24489.1 - 0.038 13.9 0.0 0.099 12.5 0.0 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain CMS1 PF14617.1 CAR24489.1 - 0.064 12.3 4.0 0.14 11.1 0.0 2.8 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit XRN_N PF03159.13 CAR24491.1 - 8.8e-107 355.8 0.1 2.7e-106 354.2 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus RTA1 PF04479.8 CAR24492.1 - 6.3e-77 258.0 10.3 9.7e-77 257.4 7.1 1.3 1 0 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 CAR24492.1 - 0.0072 15.7 1.0 0.0072 15.7 0.7 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase Acyltransferase PF01553.16 CAR24493.1 - 6.4e-07 28.8 0.0 5.1e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase PHO4 PF01384.15 CAR24493.1 - 0.035 12.7 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family BPD_transp_1 PF00528.17 CAR24493.1 - 0.12 11.8 1.2 0.34 10.3 0.3 2.0 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component TRAPP PF04051.11 CAR24494.1 - 1e-36 125.7 0.0 1.3e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Nro1 PF12753.2 CAR24495.1 - 5.2e-157 522.9 14.6 5.9e-157 522.7 10.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 FAST_1 PF06743.10 CAR24495.1 - 0.00052 19.6 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 TPR_12 PF13424.1 CAR24495.1 - 0.033 14.1 2.3 0.24 11.3 1.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat FCD PF07729.7 CAR24495.1 - 0.79 10.0 4.5 8.6 6.7 0.5 3.1 2 1 1 3 3 3 0 FCD domain TP_methylase PF00590.15 CAR24496.1 - 7.4e-40 136.8 0.1 1.3e-39 136.1 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.1 CAR24496.1 - 5.2e-05 22.1 0.1 0.00011 21.0 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.1 CAR24496.1 - 5.4e-05 23.3 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CAR24496.1 - 0.0023 17.2 0.4 1.9 7.8 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Tafi-CsgC PF10610.4 CAR24496.1 - 0.045 13.5 0.2 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein Hydrolase_like PF13242.1 CAR24497.1 - 3.4e-25 87.5 0.0 1.2e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CAR24497.1 - 1.1e-22 79.8 0.0 2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR24497.1 - 8.5e-06 26.1 0.0 0.1 12.7 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR24497.1 - 0.0023 18.4 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-AN1 PF01428.11 CAR24498.1 - 3.6e-09 36.3 12.8 5.3e-09 35.8 8.9 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger CIAPIN1 PF05093.8 CAR24499.1 - 1.8e-34 117.8 4.5 1.8e-34 117.8 3.1 2.0 3 0 0 3 3 3 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-CSL PF05207.8 CAR24499.1 - 0.68 9.4 4.6 0.94 9.0 2.2 2.0 1 1 0 1 1 1 0 CSL zinc finger Flavoprotein PF02441.14 CAR24500.1 - 3.8e-42 143.0 0.1 7e-42 142.1 0.1 1.5 1 0 0 1 1 1 1 Flavoprotein Tim54 PF11711.3 CAR24500.1 - 3.7 6.0 7.4 1.2 7.6 1.7 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PPP4R2 PF09184.6 CAR24500.1 - 5.3 6.5 28.1 0.53 9.7 15.9 1.9 2 0 0 2 2 2 0 PPP4R2 NOB1_Zn_bind PF08772.6 CAR24501.1 - 8.2e-28 96.0 0.3 1.8e-27 94.9 0.2 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF2011 PF09428.5 CAR24501.1 - 0.007 16.2 16.3 0.014 15.2 6.4 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) DUF3475 PF11961.3 CAR24501.1 - 0.0094 15.7 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3475) zf-RING_3 PF14369.1 CAR24501.1 - 0.024 14.6 0.5 0.054 13.5 0.3 1.6 1 0 0 1 1 1 0 zinc-finger Cobl PF09469.5 CAR24501.1 - 1.3 9.0 6.7 1.9 8.4 0.0 3.8 4 0 0 4 4 4 0 Cordon-bleu ubiquitin-like domain DUF4407 PF14362.1 CAR24501.1 - 2.9 6.7 7.9 4.5 6.1 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ycf1 PF05758.7 CAR24501.1 - 3.6 5.1 8.3 5.3 4.6 5.7 1.3 1 0 0 1 1 1 0 Ycf1 SGS PF05002.10 CAR24502.1 - 5.3e-26 90.1 0.8 5.3e-26 90.1 0.5 2.3 3 0 0 3 3 3 1 SGS domain CS PF04969.11 CAR24502.1 - 2.6e-13 50.3 0.3 8.3e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 CS domain TPR_11 PF13414.1 CAR24502.1 - 3.9e-06 26.4 6.8 0.00038 20.0 1.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CAR24502.1 - 0.00022 20.8 7.5 0.39 10.7 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR24502.1 - 0.00025 21.4 4.8 0.0043 17.5 0.0 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR24502.1 - 0.0033 18.0 5.4 0.028 15.0 0.3 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR24502.1 - 0.0052 16.3 8.7 0.15 11.7 0.1 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR24502.1 - 0.025 14.5 6.7 0.2 11.6 2.7 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CAR24502.1 - 0.033 13.6 2.2 0.072 12.5 1.5 1.6 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_19 PF14559.1 CAR24502.1 - 0.045 14.0 8.2 2 8.8 0.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR24502.1 - 1.2 9.7 7.9 1.3 9.6 0.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.7 CAR24503.1 - 3.2e-80 270.4 24.3 4.4e-80 270.0 15.1 2.3 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Spore_III_AB PF09548.5 CAR24503.1 - 0.026 14.2 0.8 0.026 14.2 0.6 3.2 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2852 PF11014.3 CAR24503.1 - 2.3 8.2 7.4 1 9.3 0.1 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2852) NEP PF10167.4 CAR24503.1 - 2.4 7.8 8.8 0.11 12.2 0.7 2.7 3 0 0 3 3 3 0 Uncharacterised conserved protein DUF2340 PF10209.4 CAR24504.1 - 1.8e-53 179.8 0.8 2.1e-53 179.6 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF676 PF05057.9 CAR24505.1 - 1.8e-50 171.2 0.0 2.6e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CAR24505.1 - 2.5e-05 23.9 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CAR24505.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Prominin PF05478.6 CAR24505.1 - 0.07 10.6 0.0 0.093 10.2 0.0 1.1 1 0 0 1 1 1 0 Prominin Mtp PF03821.11 CAR24505.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Abhydrolase_6 PF12697.2 CAR24505.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 CAR24507.1 - 2.6e-51 174.2 0.0 3.2e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24507.1 - 5.9e-16 58.3 0.0 8e-16 57.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR24507.1 - 2.3e-06 27.5 0.1 8.2e-06 25.7 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CAR24507.1 - 0.029 13.9 0.1 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3081 PF11280.3 CAR24508.1 - 0.081 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) Ribosomal_L3 PF00297.17 CAR24510.1 - 3.8e-119 396.9 7.3 4.6e-119 396.6 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PHD PF00628.24 CAR24511.1 - 9.3e-08 31.6 11.1 1.6e-07 30.9 7.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CAR24511.1 - 0.026 14.6 4.8 0.058 13.5 3.3 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CAR24511.1 - 0.038 13.9 1.7 0.038 13.9 1.2 1.6 2 0 0 2 2 2 0 PHD-zinc-finger like domain F-box PF00646.28 CAR24511.1 - 0.13 11.9 0.3 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 F-box domain HAD_2 PF13419.1 CAR24511.1 - 0.14 12.3 0.5 0.21 11.7 0.4 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Cytochrom_C1 PF02167.10 CAR24512.1 - 8e-83 277.4 0.0 9.6e-83 277.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CAR24512.1 - 0.00068 19.7 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CAR24512.1 - 0.0019 19.0 0.2 0.0066 17.2 0.2 2.0 1 1 0 1 1 1 1 Cytochrome c Shadoo PF14999.1 CAR24512.1 - 1 9.2 9.1 18 5.1 5.9 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective GST_N_2 PF13409.1 CAR24513.1 - 2.2e-21 75.6 0.0 5.5e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CAR24513.1 - 4.2e-08 32.9 0.0 7.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CAR24513.1 - 0.024 14.8 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CAR24513.1 - 0.1 12.6 0.0 0.55 10.2 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Alg6_Alg8 PF03155.10 CAR24515.1 - 5.6e-153 510.1 44.8 6.5e-153 509.9 31.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Vps5 PF09325.5 CAR24516.1 - 1e-75 254.0 11.9 2.4e-75 252.8 8.2 1.6 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CAR24516.1 - 8.8e-24 83.4 0.9 2.9e-23 81.8 0.2 2.3 2 0 0 2 2 2 1 PX domain Lactamase_B_2 PF12706.2 CAR24517.1 - 4.2e-37 127.5 0.1 6.5e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CAR24517.1 - 3.6e-24 84.0 0.0 1e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CAR24517.1 - 0.00017 21.2 0.1 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RabGAP-TBC PF00566.13 CAR24518.1 - 9.3e-47 159.2 0.8 9.3e-47 159.2 0.5 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain THF_DHG_CYH PF00763.18 CAR24519.1 - 4.6e-20 71.7 0.0 1.9e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CAR24519.1 - 3.4e-17 61.9 0.0 2.7e-10 39.5 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peripla_BP_4 PF13407.1 CAR24519.1 - 0.085 12.1 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Periplasmic binding protein domain FTP PF07504.8 CAR24519.1 - 0.1 12.0 0.3 0.24 10.8 0.2 1.6 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Brix PF04427.13 CAR24520.1 - 1.5e-39 135.6 1.0 2.1e-39 135.1 0.7 1.2 1 0 0 1 1 1 1 Brix domain Nucleoporin_N PF08801.6 CAR24521.1 - 1.3e-55 188.8 3.8 2.3e-55 188.0 2.7 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 CAR24521.1 - 6.4e-53 180.1 21.9 1.3e-52 179.1 15.2 1.5 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DASH_Dad2 PF08654.5 CAR24522.1 - 3.1e-32 110.6 1.8 4.4e-32 110.1 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.5 CAR24522.1 - 5e-06 25.9 1.0 1.1e-05 24.9 0.5 1.7 2 0 0 2 2 2 1 DASH complex subunit Duo1 Mre11_DNA_bind PF04152.9 CAR24522.1 - 0.027 14.3 0.8 0.043 13.6 0.5 1.5 1 1 0 1 1 1 0 Mre11 DNA-binding presumed domain Shugoshin_N PF07558.6 CAR24523.1 - 7.9e-15 54.2 2.7 2.3e-14 52.8 1.9 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 CAR24523.1 - 7.1e-09 34.9 8.0 1.9e-08 33.5 5.5 1.8 1 0 0 1 1 1 1 Shugoshin C terminus CHZ PF09649.5 CAR24523.1 - 0.075 12.2 1.6 0.19 10.9 0.4 2.2 2 0 0 2 2 2 0 Histone chaperone domain CHZ Thymidylat_synt PF00303.14 CAR24524.1 - 9.1e-119 395.3 0.0 1.1e-118 395.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DIT1_PvcA PF05141.7 CAR24524.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Syntaxin-18_N PF10496.4 CAR24525.1 - 7.3e-16 57.7 1.7 7.3e-16 57.7 1.2 2.3 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 CAR24525.1 - 0.001 18.7 3.6 0.001 18.7 2.5 2.1 2 0 0 2 2 2 1 SNARE domain Sec20 PF03908.8 CAR24525.1 - 0.012 15.2 1.2 0.012 15.2 0.9 2.8 2 1 1 3 3 3 0 Sec20 COG5 PF10392.4 CAR24525.1 - 0.11 12.4 17.3 0.18 11.7 0.8 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Tup_N PF08581.5 CAR24525.1 - 3.6 7.8 19.0 0.29 11.3 5.4 3.5 2 2 1 4 4 4 0 Tup N-terminal GTP_EFTU PF00009.22 CAR24526.1 - 2.2e-44 151.1 0.0 4.3e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 CAR24526.1 - 2.5e-12 46.7 7.2 2.5e-12 46.7 5.0 2.0 2 0 0 2 2 2 1 HBS1 N-terminus MMR_HSR1 PF01926.18 CAR24526.1 - 1.2e-07 31.6 0.1 3.2e-06 27.0 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 CAR24526.1 - 7e-06 26.1 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAR24526.1 - 0.00023 21.2 0.0 0.0005 20.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CAR24526.1 - 0.00052 20.5 0.2 0.027 14.9 0.1 2.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR24526.1 - 0.0015 17.8 0.1 0.3 10.2 0.0 2.8 3 0 0 3 3 3 1 ADP-ribosylation factor family FeoB_N PF02421.13 CAR24526.1 - 0.015 14.6 0.2 0.23 10.7 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 CAR24526.1 - 0.25 11.1 3.2 11 5.7 0.0 3.1 2 1 1 3 3 3 0 Dynamin family MRP-L20 PF12824.2 CAR24528.1 - 7e-48 162.6 5.2 7e-48 162.6 3.6 1.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_38 PF13936.1 CAR24528.1 - 0.031 13.8 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pneumo_att_G PF05539.6 CAR24528.1 - 0.045 13.1 0.8 0.056 12.8 0.6 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Frankia_peptide PF14407.1 CAR24528.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. HA2 PF04408.18 CAR24529.1 - 1.1e-26 92.7 0.0 3.5e-26 91.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR24529.1 - 1.9e-20 72.8 0.0 7.5e-20 70.8 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAR24529.1 - 3e-13 49.4 0.0 8.5e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAR24529.1 - 3.9e-06 27.0 0.0 2.9e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 CAR24529.1 - 6.5e-06 25.7 0.5 3.2e-05 23.4 0.4 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CAR24529.1 - 0.00073 18.5 0.0 0.002 17.0 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 CAR24529.1 - 0.0011 18.7 0.0 0.69 9.7 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 CAR24529.1 - 0.0014 18.4 0.5 0.022 14.6 0.2 2.7 2 1 0 2 2 1 1 AAA domain Flavi_DEAD PF07652.9 CAR24529.1 - 0.019 14.7 0.6 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain NB-ARC PF00931.17 CAR24529.1 - 0.019 13.8 0.1 0.039 12.8 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 CAR24529.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 CAR24529.1 - 0.032 13.7 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.11 CAR24529.1 - 0.039 13.1 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 CAR24529.1 - 0.05 13.3 1.9 0.11 12.1 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 CAR24529.1 - 0.05 13.8 1.2 0.34 11.1 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 CAR24529.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CAR24529.1 - 0.067 13.2 0.1 0.25 11.3 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain NACHT PF05729.7 CAR24529.1 - 0.1 12.2 0.2 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 CAR24529.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.3 3 1 1 4 4 3 0 AAA domain Peptidase_M48 PF01435.13 CAR24530.1 - 5e-31 108.0 0.0 8.3e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Kin17_mid PF10357.4 CAR24531.1 - 7.8e-40 135.4 2.8 1.4e-39 134.6 2.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 CAR24531.1 - 7.1e-06 26.0 3.4 1.6e-05 24.8 2.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR24531.1 - 3.3e-05 23.9 3.3 7.3e-05 22.8 2.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Ecl1 PF12855.2 CAR24531.1 - 0.049 12.9 0.1 0.093 12.0 0.1 1.5 1 0 0 1 1 1 0 Life-span regulatory factor zf-C2H2_2 PF12756.2 CAR24531.1 - 0.11 12.6 6.9 0.043 13.9 2.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SNARE_assoc PF09335.6 CAR24532.1 - 5.3e-15 55.7 6.4 5.3e-15 55.7 4.4 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF2207 PF09972.4 CAR24532.1 - 0.011 14.3 1.5 0.041 12.4 0.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1469 PF07332.6 CAR24532.1 - 0.08 12.6 0.0 0.08 12.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) RskA PF10099.4 CAR24532.1 - 0.09 12.5 0.6 0.27 10.9 0.1 1.9 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DUF2231 PF09990.4 CAR24532.1 - 0.61 10.4 5.9 0.73 10.2 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF2304 PF10066.4 CAR24532.1 - 1.5 8.7 5.5 0.78 9.6 1.7 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Reticulon PF02453.12 CAR24532.1 - 4.1 6.9 10.5 2.3 7.7 0.1 3.3 3 1 0 3 3 3 0 Reticulon adh_short_C2 PF13561.1 CAR24533.1 - 3.5e-32 112.0 0.3 4.3e-32 111.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR24533.1 - 1.5e-23 83.5 0.4 2.2e-23 83.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR24533.1 - 1.1e-09 38.2 0.6 4.1e-09 36.3 0.4 1.8 1 1 1 2 2 2 1 KR domain Spore_IV_A PF09547.5 CAR24533.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) U3_snoRNA_assoc PF08297.6 CAR24535.1 - 2.5e-18 66.0 7.9 2.5e-18 66.0 5.5 3.2 2 1 0 2 2 2 1 U3 snoRNA associated DUF4661 PF15576.1 CAR24535.1 - 2.1 7.9 13.7 1.9 8.0 8.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) Zip PF02535.17 CAR24536.1 - 4.5e-33 114.6 16.9 9.4e-21 74.1 3.0 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter TPR_11 PF13414.1 CAR24537.1 - 2.7e-12 46.1 4.3 1e-07 31.4 0.1 2.8 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.1 CAR24537.1 - 1.8e-08 34.1 0.4 0.01 15.7 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR24537.1 - 5.4e-08 32.1 5.0 0.041 13.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CAR24537.1 - 4.2e-07 29.3 3.8 0.31 10.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box-like PF12937.2 CAR24537.1 - 0.00011 21.8 2.1 0.00027 20.6 1.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR24537.1 - 0.00012 21.6 2.8 0.00034 20.1 2.0 1.8 1 0 0 1 1 1 1 F-box domain TPR_7 PF13176.1 CAR24537.1 - 0.00026 20.5 0.6 0.4 10.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat LRR_4 PF12799.2 CAR24537.1 - 0.00047 19.7 3.6 0.027 14.0 0.0 4.5 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) TPR_8 PF13181.1 CAR24537.1 - 0.016 14.9 3.3 2.5 8.0 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat LRR_6 PF13516.1 CAR24537.1 - 0.041 13.9 4.1 62 4.1 0.0 5.3 5 0 0 5 5 4 0 Leucine Rich repeat CbiA PF01656.18 CAR24537.1 - 0.11 11.8 0.2 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain LRR_1 PF00560.28 CAR24537.1 - 6.8 7.1 11.7 26 5.3 0.0 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat DUF3336 PF11815.3 CAR24538.1 - 1.4e-42 144.6 9.9 3.3e-42 143.4 6.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CAR24538.1 - 1.1e-29 103.8 0.0 2.7e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Rpn3_C PF08375.6 CAR24539.1 - 1.8e-20 73.1 0.9 1.8e-20 73.1 0.6 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 CAR24539.1 - 8.1e-19 67.8 2.3 3.2e-18 65.9 0.2 2.6 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CAR24539.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Med17 PF10156.4 CAR24540.1 - 1.7e-130 435.4 6.8 1.9e-130 435.2 4.7 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ilm1 PF10311.4 CAR24541.1 - 3e-40 137.4 7.6 4.3e-40 136.9 5.2 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 JmjC PF02373.17 CAR24542.1 - 8.5e-39 132.3 0.2 1.7e-38 131.4 0.2 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 CAR24542.1 - 4.4e-12 45.4 5.3 4.4e-12 45.4 3.6 2.3 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.12 CAR24542.1 - 3.8e-08 32.7 0.0 8.6e-08 31.5 0.0 1.7 1 0 0 1 1 1 1 jmjN domain RWP-RK PF02042.10 CAR24542.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain FANCL_C PF11793.3 CAR24542.1 - 0.019 14.9 3.5 0.053 13.4 2.4 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 CAR24542.1 - 0.025 14.6 0.2 0.072 13.2 0.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Myc_N PF01056.13 CAR24542.1 - 0.044 12.9 0.2 0.083 12.0 0.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region FlaF PF07309.6 CAR24542.1 - 0.069 13.0 0.5 0.32 10.8 0.0 2.3 3 0 0 3 3 3 0 Flagellar protein FlaF PHD_2 PF13831.1 CAR24542.1 - 0.31 10.3 4.0 0.14 11.5 0.5 2.2 2 0 0 2 2 2 0 PHD-finger Fer4_8 PF13183.1 CAR24542.1 - 0.33 10.9 3.6 5.3 7.1 0.1 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Prok-RING_1 PF14446.1 CAR24542.1 - 5.6 6.7 11.6 0.12 12.1 1.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Sporozoite_P67 PF05642.6 CAR24542.1 - 6.9 4.3 5.0 3.8 5.2 0.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen P5CR_dimer PF14748.1 CAR24543.1 - 7e-31 106.4 0.1 1.1e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CAR24543.1 - 4e-10 39.9 0.0 8.3e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IF2_N PF04760.10 CAR24543.1 - 0.015 14.9 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region NAD_Gly3P_dh_N PF01210.18 CAR24543.1 - 0.022 14.4 0.1 0.057 13.1 0.1 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.15 CAR24543.1 - 0.088 12.7 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ATP-synt_ab PF00006.20 CAR24544.1 - 6.1e-63 212.1 0.0 1e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAR24544.1 - 1.3e-26 93.3 0.3 2.3e-26 92.4 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAR24544.1 - 1.1e-22 80.0 3.2 1.1e-22 80.0 2.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 CAR24544.1 - 0.0022 17.1 0.2 0.0038 16.3 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 CAR24544.1 - 0.0036 16.7 0.0 0.012 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CAR24544.1 - 0.0052 15.6 0.7 0.52 9.1 0.1 2.2 2 0 0 2 2 2 2 NB-ARC domain MobB PF03205.9 CAR24544.1 - 0.0062 16.2 0.1 0.56 9.8 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CAR24544.1 - 0.023 14.3 0.2 0.075 12.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 CAR24544.1 - 0.048 13.8 0.0 0.64 10.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CAR24544.1 - 0.052 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAR24544.1 - 0.072 13.0 1.9 0.19 11.6 0.0 2.5 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 CAR24544.1 - 0.085 12.9 0.1 0.36 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAR24544.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 CAR24544.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase GCV_T PF01571.16 CAR24545.1 - 7e-07 28.8 0.0 0.033 13.5 0.0 2.8 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CAR24545.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Ribosomal_S7 PF00177.16 CAR24546.1 - 5.2e-40 136.4 1.1 7.2e-40 135.9 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MFS_1 PF07690.11 CAR24547.1 - 2.4e-31 108.7 49.5 3.3e-24 85.2 13.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAR24547.1 - 6.5e-11 41.2 19.4 1.4e-05 23.7 5.8 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 CAR24547.1 - 4e-05 22.3 19.3 6.9e-05 21.5 13.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 CAR24547.1 - 0.00081 17.5 0.5 0.00081 17.5 0.3 3.0 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 CAR24548.1 - 2.7e-10 39.5 0.5 4.8e-10 38.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR24548.1 - 1.8e-08 34.1 11.0 3.5e-08 33.2 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEXIM PF15313.1 CAR24548.1 - 0.022 14.9 0.1 0.72 10.0 0.1 2.8 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein GTP_EFTU PF00009.22 CAR24549.1 - 9e-39 132.8 0.0 1.6e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CAR24549.1 - 8e-36 121.9 0.3 1.8e-35 120.8 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CAR24549.1 - 6.2e-12 45.4 0.5 2.2e-11 43.7 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR24549.1 - 0.0074 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CAR24549.1 - 0.098 12.4 0.2 0.93 9.2 0.0 2.6 3 0 0 3 3 3 0 Dynamin family RGS PF00615.14 CAR24550.1 - 7.4e-21 74.4 1.7 3.8e-15 56.0 0.1 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.16 CAR24550.1 - 1.5e-09 37.4 0.0 2e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 CAR24551.1 - 6.4e-72 241.8 0.0 1.8e-71 240.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24551.1 - 1.8e-30 105.9 0.0 6e-30 104.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR24551.1 - 0.059 12.3 0.0 0.16 10.8 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 CAR24551.1 - 0.067 12.0 0.1 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 ORC4_C PF14629.1 CAR24552.1 - 8e-41 139.6 2.2 2e-40 138.3 1.5 1.7 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.24 CAR24552.1 - 0.00065 19.9 0.1 0.0016 18.6 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-RING_2 PF13639.1 CAR24553.1 - 6e-12 45.1 13.3 6e-12 45.1 9.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CAR24553.1 - 1.5e-08 34.6 13.3 1.6e-08 34.5 7.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CAR24553.1 - 4.7e-05 23.0 13.3 9.8e-05 22.0 9.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CAR24553.1 - 5.4e-05 22.7 10.8 0.00011 21.7 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR24553.1 - 6.7e-05 22.8 14.6 0.00018 21.4 10.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR24553.1 - 7.4e-05 22.3 13.9 7.4e-05 22.3 9.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CAR24553.1 - 0.00014 21.5 10.8 0.00053 19.7 5.7 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CAR24553.1 - 0.071 12.8 7.0 0.064 12.9 3.8 1.7 1 1 0 1 1 1 0 RING-type zinc-finger DUF2592 PF10766.4 CAR24553.1 - 0.24 10.7 1.2 1.1 8.6 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) zf-RING_6 PF14835.1 CAR24553.1 - 0.33 10.7 6.2 1 9.2 4.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CAR24553.1 - 1.5 8.4 9.8 4.6 6.9 6.8 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 CAR24553.1 - 2.9 7.4 8.1 5.9 6.4 2.6 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif RRM_6 PF14259.1 CAR24554.1 - 1.3e-09 37.8 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR24554.1 - 2e-06 27.3 0.0 3.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fmp27_WPPW PF10359.4 CAR24555.1 - 3.2e-107 358.8 17.3 3.2e-107 358.8 12.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CAR24555.1 - 2.3e-95 320.1 5.6 2.3e-95 320.1 3.9 4.3 3 1 0 3 3 3 1 Golgi-body localisation protein domain Fmp27 PF10344.4 CAR24555.1 - 6.2e-94 315.3 25.3 6.2e-94 315.3 17.5 3.0 2 1 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.4 CAR24555.1 - 4.6e-53 179.3 0.0 1.2e-52 177.9 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CAR24555.1 - 1.5e-49 167.7 0.2 6.1e-49 165.7 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CAR24555.1 - 3e-30 104.6 0.6 1.1e-29 102.8 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain CABIT PF12736.2 CAR24556.1 - 0.13 11.2 0.0 5.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Cell-cycle sustaining, positive selection, Ras PF00071.17 CAR24557.1 - 1.6e-55 186.9 0.0 1.9e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR24557.1 - 8.1e-16 58.5 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR24557.1 - 9.4e-08 31.4 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR24557.1 - 0.00048 19.6 0.1 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR24557.1 - 0.0056 15.8 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR24557.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CAR24557.1 - 0.64 9.5 3.5 5.8 6.4 0.0 3.3 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 CAR24558.1 - 3.7e-55 185.7 0.0 4.5e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR24558.1 - 1.9e-16 60.5 0.0 3.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR24558.1 - 2.4e-07 30.1 0.0 3.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR24558.1 - 7.2e-05 22.3 0.0 0.00031 20.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR24558.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.16 CAR24559.1 - 9.5e-18 63.3 0.2 1.6e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.14 CAR24560.1 - 3.8e-43 147.3 0.0 5.1e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Med10 PF09748.4 CAR24561.1 - 2.5e-42 143.7 1.6 3e-42 143.4 1.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2203 PF09969.4 CAR24561.1 - 0.045 13.9 0.3 6.1 7.0 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) BLOC1_2 PF10046.4 CAR24561.1 - 0.048 13.7 0.8 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PBS_linker_poly PF00427.16 CAR24561.1 - 0.083 12.5 0.1 0.43 10.2 0.0 1.9 1 1 0 1 1 1 0 Phycobilisome Linker polypeptide DUF3877 PF12993.2 CAR24561.1 - 0.091 12.3 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) WD40 PF00400.27 CAR24562.1 - 0.00097 18.9 4.1 0.072 13.0 0.1 4.3 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.1 CAR24562.1 - 0.022 15.0 0.0 4.3 7.7 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Nramp PF01566.13 CAR24563.1 - 3.4e-88 295.8 14.3 7.5e-88 294.7 9.9 1.5 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein RRM_1 PF00076.17 CAR24564.1 - 1.1e-36 124.2 0.3 8.9e-19 66.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24564.1 - 1.1e-31 108.5 0.0 1.2e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24564.1 - 2.3e-13 49.7 0.0 3.9e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CAR24564.1 - 0.053 13.3 0.1 0.86 9.4 0.0 2.5 2 1 0 2 2 2 0 RNA binding motif DUF2232 PF09991.4 CAR24564.1 - 1.2 8.0 6.6 2.3 7.1 4.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Collagen PF01391.13 CAR24564.1 - 2.2 7.9 14.1 11 5.6 0.2 2.8 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) UPF0020 PF01170.13 CAR24565.1 - 5.7e-14 52.0 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CAR24565.1 - 2.8e-07 30.5 0.0 5.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 CAR24565.1 - 0.0074 15.7 0.1 0.63 9.4 0.0 2.5 1 1 1 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase N6_Mtase PF02384.11 CAR24565.1 - 0.039 13.0 0.0 0.077 12.0 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.13 CAR24565.1 - 0.078 12.4 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 DNA methylase Met_10 PF02475.11 CAR24565.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ras PF00071.17 CAR24566.1 - 7.2e-32 110.0 0.0 2e-27 95.5 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CAR24566.1 - 1.7e-10 41.4 0.0 3.2e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 CAR24566.1 - 0.00038 19.7 0.3 0.0028 16.9 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR24566.1 - 0.015 14.4 0.1 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TRM13 PF05206.9 CAR24567.1 - 1.3e-76 257.2 0.0 1.7e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 CAR24567.1 - 2.4e-12 46.0 1.6 5.7e-12 44.7 1.1 1.7 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 CAR24567.1 - 7.6e-08 31.9 0.7 1.3e-07 31.1 0.5 1.4 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_23 PF13489.1 CAR24567.1 - 0.016 14.8 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Ldh_1_N PF00056.18 CAR24568.1 - 1.5e-35 122.0 0.1 3.2e-35 121.0 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAR24568.1 - 3.1e-27 95.4 0.0 8.5e-18 64.6 0.0 2.2 1 1 1 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain Bax1-I PF01027.15 CAR24569.1 - 6e-40 137.0 21.1 9e-40 136.4 14.6 1.3 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PAP2 PF01569.16 CAR24569.1 - 2.4 7.8 15.3 0.53 9.9 7.0 2.4 2 1 0 2 2 2 0 PAP2 superfamily Ribosomal_L23 PF00276.15 CAR24570.1 - 9.4e-21 73.5 1.9 9.4e-21 73.5 1.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CAR24570.1 - 1.2e-19 70.0 8.9 1.2e-19 70.0 6.2 2.3 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_S11 PF00411.14 CAR24571.1 - 5.6e-06 26.4 0.1 9.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Dicer_dimer PF03368.9 CAR24571.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Dicer dimerisation domain Pkinase PF00069.20 CAR24572.1 - 3.7e-58 196.7 0.0 4.3e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24572.1 - 2.7e-30 105.3 0.0 3.8e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR24572.1 - 2.2e-05 23.5 0.0 3.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR24572.1 - 0.00032 20.5 0.0 0.0007 19.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR24572.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CAR24572.1 - 0.026 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPF0220 PF05255.6 CAR24573.1 - 1.9e-68 228.9 2.4 2.1e-68 228.7 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3169 PF11368.3 CAR24573.1 - 0.1 11.7 3.9 0.042 13.0 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Kri1_C PF12936.2 CAR24574.1 - 3.1e-28 97.5 3.9 3.1e-28 97.5 2.7 4.2 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 CAR24574.1 - 1.4e-19 70.1 13.8 1.4e-19 70.1 9.5 5.8 3 2 2 5 5 5 1 KRI1-like family CorA PF01544.13 CAR24575.1 - 1.4e-42 145.7 0.5 2.7e-26 92.2 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF3961 PF13106.1 CAR24575.1 - 1.2 8.7 6.0 2.6 7.6 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) zf-DNL PF05180.7 CAR24577.1 - 1.3e-31 108.1 1.6 2.3e-31 107.3 1.1 1.4 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 CAR24577.1 - 0.0043 16.7 2.3 0.0074 15.9 1.6 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CSL PF05207.8 CAR24577.1 - 0.017 14.6 0.1 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 CSL zinc finger TFIIS_C PF01096.13 CAR24577.1 - 0.027 14.1 1.5 1.9 8.1 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.1 CAR24577.1 - 0.032 13.9 1.1 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CAR24577.1 - 0.035 13.7 0.8 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CAR24577.1 - 0.19 11.7 2.1 0.5 10.3 1.4 1.7 1 1 0 1 1 1 0 Zinc ribbon domain F-box-like PF12937.2 CAR24578.1 - 3.6e-07 29.8 0.7 1.2e-06 28.1 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR24578.1 - 1.2e-05 24.8 1.2 3.7e-05 23.2 0.4 2.3 2 0 0 2 2 2 1 F-box domain Glyco_hydro_72 PF03198.9 CAR24579.1 - 1.7e-134 447.7 0.7 2.4e-134 447.2 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase tRNA_anti-codon PF01336.20 CAR24580.1 - 8e-10 38.4 0.1 1.4e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 CAR24580.1 - 2.3e-07 31.1 0.6 9.9e-07 29.1 0.0 2.3 3 0 0 3 3 3 1 Replication protein A C terminal HTH_IclR PF09339.5 CAR24580.1 - 0.0036 16.8 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MoaE PF02391.12 CAR24580.1 - 0.092 12.5 0.1 9.7 6.0 0.0 2.4 2 0 0 2 2 2 0 MoaE protein TPR_11 PF13414.1 CAR24581.1 - 5.3e-13 48.4 0.9 5.2e-09 35.6 0.0 4.7 2 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 CAR24581.1 - 1.8e-08 33.6 1.3 0.0085 15.9 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAR24581.1 - 2.6e-07 29.9 0.4 0.54 9.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR24581.1 - 5.2e-06 26.9 0.3 0.024 15.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CAR24581.1 - 6.6e-05 22.7 2.3 0.089 12.7 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CAR24581.1 - 0.0001 22.5 0.0 4.7 8.1 0.0 4.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR24581.1 - 0.00012 22.3 0.1 0.068 13.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR24581.1 - 0.0046 17.0 0.2 0.11 12.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR24581.1 - 0.0055 16.4 7.5 0.89 9.4 0.0 4.8 5 1 1 6 6 6 2 Tetratricopeptide repeat F-box-like PF12937.2 CAR24581.1 - 0.1 12.3 1.2 18 5.1 0.0 2.7 2 0 0 2 2 2 0 F-box-like Myb_DNA-bind_3 PF12776.2 CAR24582.1 - 0.0062 17.1 1.2 0.012 16.1 0.1 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CAR24582.1 - 0.0074 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF904 PF06005.7 CAR24582.1 - 3.5 7.9 9.4 3.9 7.8 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ATP11 PF06644.6 CAR24583.1 - 2.1e-93 312.6 8.0 2.6e-93 312.3 5.5 1.1 1 0 0 1 1 1 1 ATP11 protein PTPlike_phytase PF14566.1 CAR24583.1 - 0.08 12.9 1.1 0.16 12.0 0.8 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Flavokinase PF01687.12 CAR24583.1 - 0.11 12.4 0.3 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Riboflavin kinase YfcL PF08891.6 CAR24583.1 - 0.19 11.6 1.4 0.41 10.6 1.0 1.5 1 0 0 1 1 1 0 YfcL protein Exonuc_VII_L PF02601.10 CAR24583.1 - 0.63 9.1 5.4 0.97 8.5 3.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PDT PF00800.13 CAR24584.1 - 1.4e-55 187.6 0.0 2.7e-55 186.7 0.0 1.4 2 0 0 2 2 2 1 Prephenate dehydratase ACT PF01842.20 CAR24584.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 ACT domain zf-rbx1 PF12678.2 CAR24585.1 - 9.7e-32 108.9 13.8 1.2e-31 108.6 9.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CAR24585.1 - 9.9e-18 63.7 10.6 1.3e-17 63.4 7.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CAR24585.1 - 4e-08 32.9 12.0 3.4e-07 29.9 8.3 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR24585.1 - 0.0013 18.3 12.4 0.0077 15.8 8.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR24585.1 - 0.0026 17.7 2.3 0.0026 17.7 1.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CAR24585.1 - 0.017 14.6 3.0 0.029 13.8 2.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 CAR24585.1 - 0.073 12.7 11.4 3.6 7.3 7.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAR24585.1 - 0.14 11.9 4.8 0.77 9.5 3.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 CAR24585.1 - 0.36 10.5 11.4 2.2 8.1 7.9 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CAR24585.1 - 0.56 10.1 7.3 0.4 10.6 0.4 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CAR24585.1 - 0.59 10.1 10.6 2.6 8.0 7.3 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 CAR24585.1 - 1.6 8.8 10.1 4.2 7.4 7.0 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CAR24585.1 - 1.7 8.8 10.1 1e+02 3.1 7.0 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain Baculo_RING PF05883.6 CAR24585.1 - 4.8 7.0 6.9 24 4.7 4.8 1.9 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain Med7 PF05983.6 CAR24586.1 - 5.7e-69 231.0 0.3 6.8e-69 230.7 0.2 1.1 1 0 0 1 1 1 1 MED7 protein Med4 PF10018.4 CAR24586.1 - 0.0017 17.7 0.9 0.0034 16.8 0.6 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Spc42p PF11544.3 CAR24586.1 - 0.038 13.9 0.5 0.15 11.9 0.0 2.2 3 0 0 3 3 3 0 Spindle pole body component Spc42p cwf21 PF08312.7 CAR24586.1 - 0.3 10.9 2.2 0.85 9.5 1.0 2.1 2 0 0 2 2 2 0 cwf21 domain 6PF2K PF01591.13 CAR24587.1 - 4.5e-54 182.8 0.0 7e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CAR24587.1 - 7.4e-07 29.1 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CAR24587.1 - 9.7e-06 24.9 0.0 2.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CAR24587.1 - 5e-05 24.1 0.0 9.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR24587.1 - 0.0044 16.1 0.0 0.0073 15.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.18 CAR24587.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase APS_kinase PF01583.15 CAR24587.1 - 0.033 13.8 0.1 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.1 CAR24587.1 - 0.033 14.4 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CAR24587.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 CAR24587.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B WD40 PF00400.27 CAR24588.1 - 8.1e-44 145.9 20.8 2.9e-11 42.7 0.5 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CAR24588.1 - 0.00021 20.1 2.3 0.68 8.6 0.2 3.5 1 1 1 2 2 2 2 Nup133 N terminal like Apc4_WD40 PF12894.2 CAR24588.1 - 0.026 14.0 0.0 0.82 9.2 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.11 CAR24589.1 - 1.6e-23 83.0 43.2 7.6e-20 70.9 12.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_1 PF00190.17 CAR24589.1 - 0.097 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Cupin 7TMR-DISM_7TM PF07695.6 CAR24589.1 - 4.4 6.9 41.7 0.67 9.5 0.6 4.5 2 2 2 4 4 4 0 7TM diverse intracellular signalling WD40 PF00400.27 CAR24590.1 - 1.2e-16 59.8 5.8 5.1e-07 29.3 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 CAR24590.1 - 0.0001 22.0 8.3 0.0003 20.5 5.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CAR24590.1 - 0.071 13.2 6.1 0.17 12.0 4.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger AstE_AspA PF04952.9 CAR24590.1 - 0.17 10.7 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family zf-C3HC4_2 PF13923.1 CAR24590.1 - 3.6 7.6 17.7 0.065 13.2 6.1 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR24590.1 - 5.9 6.6 11.2 0.39 10.4 3.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_5 PF12695.2 CAR24591.1 - 2.5e-19 69.4 0.0 3.6e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR24591.1 - 1.2e-15 58.0 0.0 5.7e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR24591.1 - 2.5e-08 33.7 0.1 0.0014 18.2 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CAR24591.1 - 3.6e-05 23.0 0.0 0.00014 21.1 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 CAR24591.1 - 0.00083 18.8 0.0 0.0017 17.8 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CAR24591.1 - 0.0048 16.3 0.1 2.3 7.6 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase DUF829 PF05705.9 CAR24591.1 - 0.0058 16.3 0.0 2.1 7.9 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) BAAT_C PF08840.6 CAR24591.1 - 0.0081 15.8 0.0 0.61 9.7 0.0 2.4 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 CAR24591.1 - 0.0082 15.5 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) DUF818 PF05677.7 CAR24591.1 - 0.068 11.8 0.0 0.087 11.5 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) LIP PF03583.9 CAR24591.1 - 0.26 10.4 0.6 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase IF4E PF01652.13 CAR24592.1 - 4.4e-58 195.4 0.3 5.3e-58 195.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Na_Ca_ex PF01699.19 CAR24593.1 - 8.2e-29 100.0 37.7 6.5e-19 67.9 5.0 3.6 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CAR24593.1 - 6.1e-10 39.3 5.6 6.1e-10 39.3 3.9 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF307) TFIIA PF03153.8 CAR24594.1 - 0.3 10.9 13.2 0.37 10.6 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.5 CAR24594.1 - 1.8 7.7 10.8 2.5 7.2 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Aminotran_3 PF00202.16 CAR24595.1 - 4.2e-103 344.7 0.0 5e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III CDC50 PF03381.10 CAR24596.1 - 4.3e-89 298.3 0.1 6.4e-89 297.8 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3533 PF12051.3 CAR24597.1 - 1.9e-134 448.2 11.9 2.2e-134 448.0 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 CAR24597.1 - 0.055 13.1 0.1 0.055 13.1 0.1 2.2 2 0 0 2 2 2 0 CDR ABC transporter LCM PF04072.9 CAR24598.1 - 1.3e-21 76.9 0.0 2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 CAR24598.1 - 1.4e-18 66.3 1.0 2.5e-08 33.5 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CAR24598.1 - 4.1e-10 39.5 4.9 0.00027 21.0 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CAR24598.1 - 8.3e-08 32.0 4.9 0.00068 19.7 0.0 5.6 5 1 1 6 6 6 1 Kelch motif Kelch_5 PF13854.1 CAR24598.1 - 6.2e-06 26.0 0.2 0.1 12.5 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Syja_N PF02383.13 CAR24599.1 - 1.1e-94 316.7 0.3 3.4e-94 315.2 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain DUF2423 PF10338.4 CAR24599.1 - 0.025 14.5 1.7 0.13 12.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) zf-DHHC PF01529.15 CAR24601.1 - 3.2e-36 124.3 7.9 3.2e-36 124.3 5.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Fer4_6 PF12837.2 CAR24601.1 - 2 8.4 6.9 4.4 7.3 4.8 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain DnaJ PF00226.26 CAR24603.1 - 2.7e-05 23.8 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.24 CAR24604.1 - 2.8e-54 182.8 0.0 2.2e-44 150.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR24604.1 - 3.7e-08 34.2 0.0 0.0011 19.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CAR24604.1 - 8.4e-05 22.0 0.6 0.018 14.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 CAR24604.1 - 0.00013 21.9 0.4 0.029 14.3 0.0 3.5 3 1 1 4 4 3 1 AAA ATPase domain Parvo_NS1 PF01057.12 CAR24604.1 - 0.00021 20.2 0.0 0.00036 19.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RuvB_N PF05496.7 CAR24604.1 - 0.00027 20.0 0.0 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CAR24604.1 - 0.00042 20.4 0.0 0.0043 17.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR24604.1 - 0.00077 19.3 0.0 0.27 11.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.9 CAR24604.1 - 0.00078 19.3 0.0 0.0032 17.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 CAR24604.1 - 0.00093 18.3 0.0 0.86 8.6 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.1 CAR24604.1 - 0.0011 19.3 0.0 0.072 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR24604.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CAR24604.1 - 0.0028 17.8 0.0 0.012 15.8 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 CAR24604.1 - 0.0063 16.2 0.0 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 CAR24604.1 - 0.0069 16.2 0.0 0.079 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CAR24604.1 - 0.009 15.9 0.0 0.094 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CAR24604.1 - 0.009 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 CAR24604.1 - 0.01 15.5 0.0 0.034 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CAR24604.1 - 0.013 14.6 0.1 0.031 13.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CAR24604.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC SKI PF01202.17 CAR24604.1 - 0.026 14.3 0.0 7.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 CAR24604.1 - 0.04 13.5 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CAR24604.1 - 0.046 12.9 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Vps4_C PF09336.5 CAR24604.1 - 0.056 13.3 0.4 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 CAR24604.1 - 0.078 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CAR24604.1 - 0.19 11.3 0.0 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hist_deacetyl PF00850.14 CAR24605.1 - 2.2e-80 270.2 0.0 3.2e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DMRL_synthase PF00885.14 CAR24606.1 - 1.2e-43 148.2 0.1 1.4e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RRM_5 PF13893.1 CAR24607.1 - 7.4e-10 38.5 0.3 1.6e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR24607.1 - 0.00013 21.5 0.6 0.00032 20.2 0.4 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3720 PF12517.3 CAR24607.1 - 1.2 9.9 7.8 0.27 11.9 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) TPR_2 PF07719.12 CAR24608.1 - 1e-30 103.1 21.0 0.00058 19.5 0.0 13.2 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_1 PF00515.23 CAR24608.1 - 7.7e-30 101.2 14.4 1.2e-05 24.7 0.0 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_11 PF13414.1 CAR24608.1 - 9.9e-29 98.8 23.0 4.5e-08 32.6 0.7 10.5 3 3 10 14 14 14 8 TPR repeat TPR_12 PF13424.1 CAR24608.1 - 8.9e-26 89.6 19.2 2.8e-07 30.3 0.3 10.2 6 2 6 12 12 12 5 Tetratricopeptide repeat Apc3 PF12895.2 CAR24608.1 - 7.1e-21 74.1 14.0 0.00059 19.9 0.2 8.2 6 2 3 9 9 9 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CAR24608.1 - 9.4e-19 65.7 17.2 0.0039 16.8 0.0 11.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 CAR24608.1 - 1.2e-18 67.1 6.7 0.0062 16.8 0.0 10.3 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.1 CAR24608.1 - 5.8e-18 65.0 2.9 0.011 16.4 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAR24608.1 - 2.4e-17 61.8 0.3 0.041 14.5 0.0 11.9 9 2 4 13 13 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR24608.1 - 9.9e-15 53.1 10.2 0.0046 16.6 0.0 9.6 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAR24608.1 - 2.5e-10 39.7 9.9 0.67 10.2 0.0 11.6 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_6 PF13174.1 CAR24608.1 - 1.1e-08 34.9 8.4 5.7 7.6 0.0 11.7 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAR24608.1 - 0.0039 17.0 26.0 0.46 10.4 0.0 8.4 11 0 0 11 11 10 2 Tetratricopeptide repeat PPR PF01535.15 CAR24608.1 - 0.0042 16.9 0.3 18 5.6 0.0 4.9 3 0 0 3 3 3 0 PPR repeat Sld5 PF05916.6 CAR24609.1 - 4e-12 46.3 0.0 5.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein PEX11 PF05648.9 CAR24610.1 - 2e-59 200.5 2.2 2.4e-59 200.3 1.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spt20 PF12090.3 CAR24611.1 - 2.7e-55 186.5 0.7 2.7e-55 186.5 0.5 3.8 3 1 0 3 3 3 2 Spt20 family DCP1 PF06058.8 CAR24612.1 - 2.2e-14 53.5 0.4 6.8e-08 32.6 0.0 3.1 2 1 1 3 3 3 3 Dcp1-like decapping family SSF PF00474.12 CAR24613.1 - 3.2e-17 62.2 25.0 3.2e-17 62.2 17.3 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family Globin PF00042.17 CAR24614.1 - 1.4e-07 31.8 0.0 6.7e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Globin Flocculin PF00624.13 CAR24615.1 - 6.3e-181 586.0 411.6 4.9e-16 58.2 15.7 19.7 19 2 2 21 21 21 15 Flocculin repeat Candida_ALS_N PF11766.3 CAR24615.1 - 1e-32 113.0 6.6 1e-32 113.0 4.6 2.4 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding DUF4221 PF13970.1 CAR24615.1 - 0.12 11.6 2.0 0.21 10.8 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Pectate_lyase PF03211.8 CAR24616.1 - 1.1e-58 198.1 3.5 1.3e-58 197.9 2.4 1.0 1 0 0 1 1 1 1 Pectate lyase DUF3494 PF11999.3 CAR24616.1 - 0.012 15.2 1.4 0.02 14.5 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) Methyltransf_11 PF08241.7 CAR24617.1 - 2.7e-10 40.5 0.0 6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR24617.1 - 1.4e-08 35.1 0.0 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR24617.1 - 5.9e-08 32.5 0.0 1.3e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR24617.1 - 6.8e-08 32.2 0.0 9.5e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR24617.1 - 1e-07 32.4 0.0 1.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR24617.1 - 8.6e-06 26.0 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR24617.1 - 0.0002 20.5 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CAR24617.1 - 0.00029 20.8 0.0 0.00065 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR24617.1 - 0.029 13.7 0.0 0.053 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.11 CAR24618.1 - 5.6e-09 35.1 37.2 9.9e-08 31.0 25.8 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sir1 PF11603.3 CAR24619.1 - 0.00024 21.2 0.1 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 Regulatory protein Sir1 DUP PF00674.13 CAR24619.1 - 0.059 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 DUP family Cys_Met_Meta_PP PF01053.15 CAR24620.1 - 2.5e-29 101.7 0.0 5.5e-29 100.6 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CAR24620.1 - 0.00046 19.2 0.0 0.00071 18.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Hexokinase_2 PF03727.11 CAR24621.1 - 2.9e-94 314.8 0.0 4.2e-94 314.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CAR24621.1 - 8e-87 289.8 0.0 1.1e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase SAC3_GANP PF03399.11 CAR24622.1 - 5.2e-31 107.7 0.7 6.7e-31 107.4 0.5 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CAR24622.1 - 9.5e-20 70.8 0.1 1.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Ppx-GppA PF02541.11 CAR24623.1 - 1.1e-69 234.7 0.0 1.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF2420 PF10336.4 CAR24624.1 - 1.2e-30 105.4 0.1 1.8e-30 104.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Clat_adaptor_s PF01217.15 CAR24625.1 - 5.5e-11 42.3 2.2 1.4e-10 41.0 1.6 1.7 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 CAR24625.1 - 2.1e-09 36.8 0.2 3.8e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Proteasome PF00227.21 CAR24626.1 - 1.9e-27 95.8 0.0 2.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit PDEase_II PF02112.10 CAR24627.1 - 1.7e-65 221.1 0.0 6.1e-65 219.3 0.0 1.7 1 1 1 2 2 2 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CAR24627.1 - 8.8e-06 25.3 0.1 1.3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CAR24627.1 - 0.042 13.4 0.1 0.6 9.7 0.1 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF2638 PF10937.3 CAR24628.1 - 2e-25 90.0 0.0 2.2e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Brr6_like_C_C PF10104.4 CAR24629.1 - 4.1e-42 142.8 1.2 4.9e-42 142.6 0.8 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Aldo_ket_red PF00248.16 CAR24630.1 - 8.4e-47 159.3 0.0 1e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RAI1 PF08652.6 CAR24631.1 - 1.8e-26 91.6 0.1 3.8e-26 90.6 0.1 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease tRNA-synt_1c PF00749.16 CAR24632.1 - 1.7e-116 388.2 0.1 2.3e-116 387.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CAR24632.1 - 1.1e-37 129.3 0.8 2.4e-37 128.2 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CAR24632.1 - 2.1e-05 24.9 0.0 6.4e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CAR24632.1 - 0.0021 17.9 0.0 0.0069 16.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CAR24632.1 - 0.0023 17.8 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF155 PF02582.9 CAR24633.1 - 7.7e-60 201.7 0.2 1.3e-59 201.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SecG PF03840.9 CAR24633.1 - 0.14 11.8 0.2 0.42 10.3 0.2 1.8 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Plus-3 PF03126.13 CAR24634.1 - 1.9e-35 121.1 0.1 6.5e-35 119.4 0.1 2.0 1 0 0 1 1 1 1 Plus-3 domain Lyase_8_C PF02884.12 CAR24634.1 - 0.022 14.7 0.1 0.068 13.1 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain A_deamin PF02137.13 CAR24635.1 - 1.3e-65 221.9 0.0 1.6e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ank_2 PF12796.2 CAR24636.1 - 1.9e-13 50.5 0.1 1.3e-06 28.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CAR24636.1 - 1.4e-11 43.5 0.3 2.5e-05 23.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CAR24636.1 - 3.5e-07 29.8 0.0 0.095 13.0 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CAR24636.1 - 2.7e-06 27.7 0.4 0.00039 20.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CAR24636.1 - 3.1e-06 27.2 0.0 0.00058 20.0 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) IBN_N PF03810.14 CAR24637.1 - 9.7e-07 28.6 0.2 0.00026 20.8 0.0 3.5 3 0 0 3 3 3 2 Importin-beta N-terminal domain DUF1546 PF07571.8 CAR24637.1 - 0.05 13.7 0.1 0.46 10.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) QRPTase_C PF01729.14 CAR24638.1 - 5.6e-59 198.4 0.0 7.5e-59 198.0 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 CAR24638.1 - 1.4e-22 79.2 0.1 4e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain FMN_dh PF01070.13 CAR24638.1 - 0.037 12.8 0.0 0.065 12.0 0.0 1.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TMP-TENI PF02581.12 CAR24638.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI APC10 PF03256.11 CAR24639.1 - 2.8e-54 183.6 0.0 3.6e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CAR24639.1 - 0.00012 21.8 0.2 0.00039 20.2 0.1 2.0 2 1 0 2 2 2 1 F5/8 type C domain Cse1 PF08506.5 CAR24640.1 - 2.5e-162 539.6 2.1 2.5e-162 539.6 1.4 2.3 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 CAR24640.1 - 6.7e-109 364.0 3.0 1e-108 363.4 2.1 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CAR24640.1 - 2.2e-13 49.8 0.1 1.1e-11 44.4 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CAR24640.1 - 0.0042 17.0 0.4 0.09 12.6 0.0 3.6 3 1 0 3 3 3 1 Exportin 1-like protein UME PF08064.8 CAR24640.1 - 0.042 13.8 0.4 4.4 7.3 0.0 3.2 2 1 1 3 3 3 0 UME (NUC010) domain Alba PF01918.16 CAR24640.1 - 0.16 11.5 0.2 6.3 6.4 0.0 3.3 3 0 0 3 3 3 0 Alba CBFB_NFYA PF02045.10 CAR24641.1 - 5.2e-28 97.3 8.5 1.1e-27 96.3 5.9 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B GIDA PF01134.17 CAR24643.1 - 2.8e-154 513.7 0.0 3.5e-154 513.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CAR24643.1 - 2.1e-18 66.1 0.0 5.4e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 CAR24643.1 - 4.6e-07 29.9 0.3 1.1e-06 28.7 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CAR24643.1 - 1.8e-06 27.3 0.8 2.6e-06 26.7 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 CAR24643.1 - 1.9e-05 23.7 4.7 0.0071 15.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CAR24643.1 - 0.0074 15.1 3.5 0.0074 15.1 2.4 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 CAR24643.1 - 0.01 16.2 0.2 0.023 15.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CAR24643.1 - 1.6 7.1 5.6 4.3 5.7 1.1 2.7 3 0 0 3 3 3 0 HI0933-like protein GARS_A PF01071.14 CAR24644.1 - 2.4e-81 271.9 0.0 4e-81 271.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CAR24644.1 - 2.4e-34 117.7 0.0 8.9e-34 115.9 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CAR24644.1 - 6.7e-31 107.3 0.0 1.5e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CAR24644.1 - 6.4e-28 96.7 0.3 2.1e-27 95.1 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CAR24644.1 - 1.3e-15 57.4 2.8 1.3e-15 57.4 1.9 2.8 4 0 0 4 4 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 CAR24644.1 - 6.3e-15 55.3 0.0 3.5e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 CAR24644.1 - 4.4e-09 35.9 0.0 9.1e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CAR24644.1 - 6e-08 31.8 0.0 1.5e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 CAR24644.1 - 1.3e-06 27.9 0.1 3.4e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 CAR24644.1 - 4.1e-06 26.7 0.0 1.5e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 CAR24644.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CAR24644.1 - 0.013 15.0 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CAR24644.1 - 0.086 12.2 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Mito_carr PF00153.22 CAR24645.1 - 3.6e-42 141.9 5.2 5.1e-20 70.9 0.2 4.6 4 1 0 4 4 4 4 Mitochondrial carrier protein Peptidase_M20 PF01546.23 CAR24646.1 - 6e-28 97.6 0.0 8.2e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR24646.1 - 2.3e-10 40.1 0.0 4.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF848 PF05852.6 CAR24646.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Sec15 PF04091.7 CAR24647.1 - 1.5e-96 323.3 6.1 1.5e-96 323.3 4.2 2.1 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like THUMP PF02926.12 CAR24648.1 - 3.4e-25 88.6 0.3 5.5e-25 87.9 0.2 1.3 1 0 0 1 1 1 1 THUMP domain DUF1077 PF06417.7 CAR24649.1 - 2.9e-45 152.6 7.5 3.7e-45 152.3 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) PsbX PF06596.6 CAR24649.1 - 0.14 11.8 0.3 0.14 11.8 0.2 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Adaptin_binding PF10199.4 CAR24651.1 - 0.0001 22.6 0.5 0.43 10.8 0.0 2.3 1 1 1 2 2 2 2 Alpha and gamma adaptin binding protein p34 DnaJ PF00226.26 CAR24652.1 - 9.6e-15 54.0 5.5 1.8e-14 53.1 3.6 1.6 2 0 0 2 2 2 1 DnaJ domain SAPS PF04499.10 CAR24653.1 - 2.2e-161 537.7 7.3 3.3e-161 537.1 5.1 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein AdoHcyase PF05221.12 CAR24655.1 - 7.7e-140 464.4 0.1 8.9e-140 464.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CAR24655.1 - 4.6e-85 283.4 1.4 7.3e-85 282.7 1.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CAR24655.1 - 5e-07 29.0 0.0 9.3e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CAR24655.1 - 0.0011 18.3 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CAR24655.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CAR24655.1 - 0.091 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SPRY PF00622.23 CAR24656.1 - 2.1e-20 73.0 0.1 4.3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 CAR24656.1 - 4.3e-17 62.1 1.7 8e-17 61.2 1.2 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Daxx PF03344.10 CAR24656.1 - 0.00074 18.1 11.0 0.00097 17.7 7.6 1.2 1 0 0 1 1 1 1 Daxx Family BUD22 PF09073.5 CAR24656.1 - 0.013 14.6 19.9 0.022 13.8 13.8 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 CAR24656.1 - 0.056 11.4 15.9 0.096 10.7 11.1 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 CAR24656.1 - 0.19 10.9 22.2 0.32 10.2 15.4 1.3 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.10 CAR24656.1 - 1.4 8.1 7.2 2.2 7.4 5.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist COX4 PF02936.9 CAR24658.1 - 5.7e-11 42.3 0.1 7.2e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV PMSR PF01625.16 CAR24659.1 - 1.6e-51 174.2 0.9 2.1e-51 173.9 0.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HRXXH PF13933.1 CAR24659.1 - 0.065 12.6 0.7 0.44 9.9 0.5 1.9 1 1 0 1 1 1 0 Putative peptidase family DUF3889 PF13028.1 CAR24659.1 - 0.12 11.9 2.2 0.28 10.8 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3889) XPG_I PF00867.13 CAR24660.1 - 9.3e-22 76.9 0.0 2.1e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CAR24660.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CAR24660.1 - 0.0076 15.7 0.0 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing GATA PF00320.22 CAR24661.1 - 2.1e-14 52.5 2.8 4.3e-14 51.5 2.0 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CAR24661.1 - 0.17 11.1 0.4 0.32 10.3 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding UAA PF08449.6 CAR24662.1 - 3.2e-18 65.7 20.8 3.8e-18 65.4 14.4 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CAR24662.1 - 3.9e-09 36.3 7.9 3.9e-09 36.3 5.5 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CAR24662.1 - 5.6e-06 25.6 2.6 5.6e-06 25.6 1.8 2.0 3 0 0 3 3 3 1 Nucleotide-sugar transporter EamA PF00892.15 CAR24662.1 - 0.00016 21.7 28.0 0.0031 17.5 4.5 2.3 2 1 0 2 2 2 2 EamA-like transporter family ER_lumen_recept PF00810.13 CAR24662.1 - 0.016 15.6 0.8 0.016 15.6 0.6 2.9 2 2 1 3 3 3 0 ER lumen protein retaining receptor Multi_Drug_Res PF00893.14 CAR24662.1 - 4.1 7.9 15.4 6.2 7.3 0.4 3.2 3 1 1 4 4 4 0 Small Multidrug Resistance protein Nse5 PF08691.5 CAR24663.1 - 5.4e-13 48.2 1.6 1.7e-12 46.6 1.1 1.7 1 1 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 HAD_2 PF13419.1 CAR24664.1 - 1.8e-26 93.4 0.2 2.8e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR24664.1 - 0.00085 19.7 0.0 0.0079 16.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Vps51 PF08700.6 CAR24665.1 - 0.034 13.9 0.1 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 DUF605 PF04652.11 CAR24665.1 - 0.21 10.9 21.0 0.029 13.7 11.5 1.6 2 0 0 2 2 2 0 Vta1 like ABC_tran PF00005.22 CAR24667.1 - 3.9e-49 166.4 0.1 5.4e-24 85.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CAR24667.1 - 8.7e-21 75.1 0.8 3.6e-05 23.8 0.0 4.2 2 2 1 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 CAR24667.1 - 9.4e-21 73.4 0.9 9.4e-21 73.4 0.6 3.3 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 CAR24667.1 - 3.2e-10 39.6 2.9 0.17 11.1 0.0 4.8 3 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CAR24667.1 - 2.4e-08 34.8 0.0 0.0013 19.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CAR24667.1 - 5e-08 32.2 0.1 4.9e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAR24667.1 - 1.1e-07 31.2 0.0 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CAR24667.1 - 3.4e-07 30.7 0.0 0.009 16.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CAR24667.1 - 3.4e-07 30.4 0.1 0.037 14.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 CAR24667.1 - 7.3e-07 29.5 0.1 0.047 13.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 CAR24667.1 - 2.8e-06 27.1 1.8 0.041 13.5 0.0 3.1 4 0 0 4 4 2 2 NACHT domain MMR_HSR1 PF01926.18 CAR24667.1 - 3.1e-06 27.1 0.3 0.0076 16.1 0.1 3.4 3 2 0 3 3 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CAR24667.1 - 4.5e-06 26.7 0.1 0.13 12.4 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA PF00004.24 CAR24667.1 - 6.3e-06 26.4 0.1 0.038 14.1 0.0 3.7 2 2 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CAR24667.1 - 2.4e-05 24.2 0.0 0.1 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CAR24667.1 - 3.2e-05 23.6 0.2 0.0018 17.9 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CAR24667.1 - 8.3e-05 22.9 13.0 0.016 15.5 0.0 4.0 5 0 0 5 5 3 2 AAA domain AAA_33 PF13671.1 CAR24667.1 - 0.00014 21.7 0.0 0.47 10.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 CAR24667.1 - 0.00019 20.9 1.6 0.2 11.0 0.1 3.3 3 1 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 CAR24667.1 - 0.00021 21.3 0.0 0.95 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAR24667.1 - 0.00039 20.4 1.9 0.44 10.5 0.1 3.4 2 2 0 3 3 3 2 AAA ATPase domain VirE PF05272.6 CAR24667.1 - 0.00056 19.4 0.3 0.37 10.2 0.0 2.8 3 0 0 3 3 3 1 Virulence-associated protein E AAA_25 PF13481.1 CAR24667.1 - 0.00067 19.1 0.0 1.2 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.1 CAR24667.1 - 0.00092 18.3 0.0 1.5 7.8 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain T2SE PF00437.15 CAR24667.1 - 0.0014 17.5 0.0 0.011 14.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.9 CAR24667.1 - 0.0016 18.1 0.1 1.7 8.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MCM PF00493.18 CAR24667.1 - 0.0024 16.7 1.1 1.2 7.8 0.0 3.0 3 0 0 3 3 3 1 MCM2/3/5 family NB-ARC PF00931.17 CAR24667.1 - 0.0042 15.9 0.0 1.7 7.4 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain ArgK PF03308.11 CAR24667.1 - 0.0052 15.6 0.0 0.79 8.4 0.0 2.7 3 0 0 3 3 3 1 ArgK protein SbcCD_C PF13558.1 CAR24667.1 - 0.0063 16.3 1.0 1.2 9.1 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 CAR24667.1 - 0.017 14.8 5.0 1.7 8.3 0.0 3.4 3 1 1 4 4 4 0 Archaeal ATPase DAP3 PF10236.4 CAR24667.1 - 0.019 13.9 1.3 5.3 5.8 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 UPF0079 PF02367.12 CAR24667.1 - 0.021 14.4 0.5 4.8 6.8 0.0 3.2 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 CAR24667.1 - 0.021 13.7 0.4 3.6 6.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF815) Rad17 PF03215.10 CAR24667.1 - 0.022 13.4 0.1 3.2 6.3 0.0 2.5 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 CAR24667.1 - 0.027 14.2 0.1 0.89 9.2 0.0 2.5 2 0 0 2 2 2 0 NTPase DUF87 PF01935.12 CAR24667.1 - 0.036 13.8 2.4 6.7 6.4 0.0 3.1 3 1 0 3 3 2 0 Domain of unknown function DUF87 AAA_24 PF13479.1 CAR24667.1 - 0.039 13.5 1.2 3.9 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CAR24667.1 - 0.04 13.4 0.4 1.5 8.2 0.0 2.9 4 0 0 4 4 2 0 FtsK/SpoIIIE family Septin PF00735.13 CAR24667.1 - 0.044 12.7 0.2 8.6 5.2 0.0 2.7 3 0 0 3 3 2 0 Septin SRP54 PF00448.17 CAR24667.1 - 0.055 12.9 0.6 4.6 6.6 0.0 3.4 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 CAR24667.1 - 0.064 12.7 0.6 7.6 6.0 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CAR24667.1 - 0.095 12.5 5.9 5.4 6.7 0.0 4.0 4 1 1 5 5 4 0 Dynamin family G-alpha PF00503.15 CAR24667.1 - 9.2 4.8 7.9 15 4.1 2.2 2.7 3 1 0 3 3 3 0 G-protein alpha subunit NIF3 PF01784.13 CAR24670.1 - 1.2e-63 214.8 0.0 1.5e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 CAR24671.1 - 1.1e-19 70.1 0.0 1.3e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Oxidored_FMN PF00724.15 CAR24673.1 - 2.1e-123 411.7 0.0 2.4e-123 411.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Kinesin PF00225.18 CAR24674.1 - 4.3e-115 383.9 0.1 8.7e-115 382.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DEAD PF00270.24 CAR24674.1 - 0.051 13.0 0.0 0.2 11.1 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase Cyclin PF08613.6 CAR24675.1 - 2.1e-05 24.9 0.1 3.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAR24675.1 - 0.034 13.7 0.0 0.074 12.6 0.0 1.5 1 1 0 1 1 1 0 Cyclin, N-terminal domain WD40 PF00400.27 CAR24676.1 - 1.5e-15 56.4 11.6 2.8e-08 33.3 0.2 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CAR24676.1 - 0.016 14.9 0.2 0.25 11.0 0.0 2.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 CAR24676.1 - 0.019 14.2 0.0 10 5.2 0.0 2.9 2 1 1 3 3 3 0 TUP1-like enhancer of split Nup160 PF11715.3 CAR24676.1 - 0.087 10.9 0.0 0.43 8.6 0.0 2.0 2 1 0 2 2 2 0 Nucleoporin Nup120/160 SNARE PF05739.14 CAR24677.1 - 2.5e-12 46.2 3.7 2.5e-12 46.2 2.5 1.9 2 0 0 2 2 2 1 SNARE domain PX PF00787.19 CAR24677.1 - 6.4e-12 45.2 1.0 8.7e-12 44.8 0.1 1.7 2 0 0 2 2 2 1 PX domain UreF PF01730.11 CAR24677.1 - 1.3 9.1 4.8 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 UreF OSTbeta PF15048.1 CAR24677.1 - 1.4 8.9 5.9 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein ATP_bind_3 PF01171.15 CAR24678.1 - 1.4e-18 67.0 0.0 2.6e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 CAR24678.1 - 0.00084 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 CAR24678.1 - 0.00092 17.8 0.0 0.0015 17.1 0.0 1.3 1 1 0 1 1 1 1 tRNA methyl transferase Ras PF00071.17 CAR24681.1 - 6.2e-62 207.7 0.4 7.4e-62 207.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR24681.1 - 3.4e-20 72.7 0.0 5.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR24681.1 - 5.9e-14 51.6 0.0 7.7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAR24681.1 - 2e-07 30.9 0.0 3.6e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR24681.1 - 6.2e-06 25.7 0.1 1.7e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 CAR24681.1 - 2e-05 23.8 0.5 2.4e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 CAR24681.1 - 0.00018 20.7 0.1 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 CAR24681.1 - 0.0012 18.0 0.4 0.0028 16.8 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 CAR24681.1 - 0.002 17.2 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain SRPRB PF09439.5 CAR24681.1 - 0.0057 15.8 0.1 0.012 14.7 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CAR24681.1 - 0.0064 15.9 0.0 0.009 15.5 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CAR24681.1 - 0.0075 16.4 0.2 0.027 14.6 0.1 1.8 1 1 1 2 2 2 1 AAA domain TraG_N PF07916.6 CAR24681.1 - 0.018 13.5 0.1 0.022 13.2 0.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Septin PF00735.13 CAR24681.1 - 0.022 13.8 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 CAR24681.1 - 0.029 14.6 0.7 0.049 13.9 0.5 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CAR24681.1 - 0.033 14.1 0.7 0.19 11.6 0.5 2.2 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 CAR24681.1 - 0.042 13.1 0.2 0.07 12.4 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1128 PF06569.6 CAR24681.1 - 0.049 13.3 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1128) NTPase_1 PF03266.10 CAR24681.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 CAR24681.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MgpC PF05220.7 CAR24681.1 - 0.15 11.1 1.0 0.6 9.1 0.1 2.0 1 1 1 2 2 2 0 MgpC protein precursor CHZ PF09649.5 CAR24682.1 - 4.4e-20 70.6 1.5 2e-19 68.4 1.0 2.2 1 0 0 1 1 1 1 Histone chaperone domain CHZ Peptidase_S64 PF08192.6 CAR24682.1 - 0.85 7.8 9.9 0.91 7.7 6.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4615 PF15393.1 CAR24682.1 - 8.7 6.5 8.8 8.4 6.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) LSM PF01423.17 CAR24683.1 - 3.2e-15 55.4 0.0 5.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 LSM domain zf-C2H2 PF00096.21 CAR24684.1 - 1.2e-07 31.5 14.4 0.00067 19.8 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR24684.1 - 1.3e-07 31.5 17.3 8.5e-05 22.6 3.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR24684.1 - 1.9e-07 30.9 10.1 0.0011 19.1 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR24684.1 - 0.049 13.7 4.1 0.22 11.6 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AMPKBI PF04739.10 CAR24685.1 - 3.6e-33 113.4 0.8 3.6e-33 113.4 0.6 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4557 PF15101.1 CAR24685.1 - 0.074 12.8 4.2 0.13 12.0 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SPT16 PF08644.6 CAR24686.1 - 4.4e-52 175.9 0.8 9.6e-52 174.8 0.0 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CAR24686.1 - 3.8e-46 156.5 2.6 7.9e-46 155.5 0.0 2.7 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CAR24686.1 - 3.4e-24 85.5 0.0 6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CAR24686.1 - 1.4e-19 69.8 0.0 2.3e-18 65.9 0.0 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Clathrin PF00637.15 CAR24687.1 - 1.4e-191 627.7 45.4 1.7e-31 108.7 0.8 8.3 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CAR24687.1 - 5.1e-25 87.1 0.9 3e-24 84.6 0.1 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 CAR24687.1 - 8e-15 54.0 3.2 0.0058 16.8 0.1 5.7 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.5 CAR24687.1 - 2.3e-11 42.4 1.7 9.1e-11 40.5 0.1 2.5 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 CAR24687.1 - 0.061 12.9 8.0 29 4.4 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Ank_2 PF12796.2 CAR24687.1 - 0.064 13.6 0.1 0.62 10.4 0.0 2.9 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) PPR PF01535.15 CAR24687.1 - 0.26 11.3 2.5 79 3.5 0.0 5.2 5 1 1 6 6 6 0 PPR repeat ACOX PF01756.14 CAR24688.1 - 1.3e-52 177.9 0.0 2.7e-52 176.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CAR24688.1 - 2.3e-16 59.0 0.2 4.5e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CAR24688.1 - 5.5e-10 39.6 0.0 1.8e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CAR24688.1 - 0.0031 17.6 0.0 0.06 13.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain CDP-OH_P_transf PF01066.16 CAR24689.1 - 2.4e-12 47.0 3.3 4.4e-12 46.1 2.3 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Peptidase_S10 PF00450.17 CAR24690.1 - 1.3e-99 334.1 0.1 1.6e-99 333.8 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Nop14 PF04147.7 CAR24690.1 - 0.024 12.5 38.6 0.035 12.0 26.8 1.2 1 0 0 1 1 1 0 Nop14-like family Aminotran_1_2 PF00155.16 CAR24691.1 - 3.3e-22 78.9 0.0 5.3e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CAR24691.1 - 0.0098 14.4 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 CAR24691.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Sugar_tr PF00083.19 CAR24692.1 - 2.1e-42 145.2 16.9 3.2e-42 144.6 11.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR24692.1 - 2.7e-36 124.9 22.3 2.7e-36 124.9 15.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2990 PF11693.3 CAR24692.1 - 0.063 13.1 0.2 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Phosphorylase PF00343.15 CAR24693.1 - 0 1033.3 5.6 0 1033.0 3.8 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase YmgB PF10798.3 CAR24693.1 - 0.2 11.5 3.7 0.23 11.2 0.3 2.5 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR MCM PF00493.18 CAR24694.1 - 2.7e-138 460.3 0.7 3.8e-138 459.8 0.5 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR24694.1 - 2.9e-20 72.9 0.1 2e-19 70.2 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR24694.1 - 8.9e-07 28.2 0.0 3.6e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAR24694.1 - 0.002 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CAR24694.1 - 0.0039 16.7 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CAR24694.1 - 0.023 14.3 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_S6 PF01250.12 CAR24694.1 - 0.06 13.2 0.5 4.6 7.1 0.0 3.4 3 1 1 4 4 4 0 Ribosomal protein S6 SKN1 PF03935.10 CAR24695.1 - 3e-253 840.4 4.2 3.8e-253 840.1 2.9 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SIS PF01380.17 CAR24696.1 - 9.7e-11 41.3 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 CAR24696.1 - 4.2e-07 29.7 0.0 0.0061 16.2 0.0 2.3 1 1 1 2 2 2 2 SIS domain Rod-binding PF10135.4 CAR24696.1 - 0.12 12.3 0.4 0.31 11.0 0.3 1.6 1 0 0 1 1 1 0 Rod binding protein Borrelia_P83 PF05262.6 CAR24697.1 - 0.25 9.5 30.4 0.37 8.9 21.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF946 PF06101.6 CAR24698.1 - 4.7e-08 31.4 2.4 1.1e-07 30.2 1.7 1.6 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) GCR1_C PF12550.3 CAR24699.1 - 1.5e-21 76.0 0.0 3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Cwf_Cwc_15 PF04889.7 CAR24699.1 - 0.16 11.6 9.8 0.27 10.9 6.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Propeptide_C1 PF08127.8 CAR24699.1 - 0.18 11.4 2.8 0.57 9.8 0.0 3.0 4 0 0 4 4 4 0 Peptidase family C1 propeptide DUF506 PF04720.7 CAR24699.1 - 2 7.9 5.9 3.7 7.1 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF506) MFS_1 PF07690.11 CAR24700.1 - 8.5e-33 113.5 29.5 8.5e-33 113.5 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR24700.1 - 1.6e-14 53.3 18.6 1.6e-14 53.3 12.9 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter NCA2 PF08637.5 CAR24702.1 - 2e-93 312.5 0.7 2.9e-93 311.9 0.5 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 SH3_1 PF00018.23 CAR24703.1 - 2.8e-14 52.2 0.0 4.6e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR24703.1 - 9.1e-14 50.7 0.0 1.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR24703.1 - 1.4e-10 40.5 0.0 2.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 CAR24703.1 - 0.16 11.3 18.0 0.19 11.0 12.5 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CAR24703.1 - 0.69 8.0 22.4 0.82 7.8 15.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tmemb_170 PF10190.4 CAR24704.1 - 0.00094 19.2 6.6 0.0013 18.7 4.6 1.2 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF457 PF04307.9 CAR24704.1 - 0.058 12.7 10.7 0.24 10.7 7.4 2.1 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF2306 PF10067.4 CAR24704.1 - 3.5 7.8 10.2 4.1 7.5 2.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) Proteasome PF00227.21 CAR24705.1 - 8.7e-58 194.7 0.3 1.1e-57 194.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR24705.1 - 1.6e-12 46.5 0.1 2.9e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WW PF00397.21 CAR24706.1 - 5.1e-09 35.8 7.6 8.4e-06 25.5 3.7 2.8 2 0 0 2 2 2 2 WW domain FF PF01846.14 CAR24706.1 - 7.6e-08 32.1 0.5 7.6e-08 32.1 0.4 3.4 4 0 0 4 4 4 1 FF domain Aldo_ket_red PF00248.16 CAR24707.1 - 9.9e-49 165.6 0.0 1.3e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cys_Met_Meta_PP PF01053.15 CAR24707.1 - 0.025 12.8 0.0 0.035 12.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CoA_binding PF02629.14 CAR24709.1 - 8.4e-25 87.1 5.1 8.5e-25 87.0 1.4 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CAR24709.1 - 7.2e-23 80.8 0.7 1.3e-22 80.0 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CAR24709.1 - 1.3e-09 37.7 0.1 2.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CAR24709.1 - 2.9e-05 24.1 0.1 0.00015 21.9 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain TPK_catalytic PF04263.11 CAR24710.1 - 8.2e-20 70.6 0.0 6.1e-17 61.3 0.0 2.2 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CAR24710.1 - 1.3e-13 50.4 0.0 2.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TFIID-18kDa PF02269.11 CAR24711.1 - 4.9e-36 122.4 0.3 2.2e-35 120.3 0.1 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit AAA PF00004.24 CAR24712.1 - 5.1e-05 23.4 0.0 0.00016 21.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR24712.1 - 0.00015 21.8 0.1 0.12 12.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 CAR24712.1 - 0.00074 19.4 0.0 0.0068 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 CAR24712.1 - 0.0025 17.4 0.1 0.0065 16.1 0.0 1.7 1 1 0 1 1 1 1 Bacterial dnaA protein KH_1 PF00013.24 CAR24713.1 - 0.00039 20.0 0.4 0.00083 18.9 0.3 1.5 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 CAR24714.1 - 8.2e-74 248.8 17.4 2.5e-34 118.6 1.0 4.1 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins G-patch_2 PF12656.2 CAR24715.1 - 2.1e-21 75.5 0.4 1e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site She9_MDM33 PF05546.6 CAR24716.1 - 1.8e-93 311.8 15.6 9.4e-92 306.2 8.6 2.2 2 0 0 2 2 2 2 She9 / Mdm33 family Tropomyosin_1 PF12718.2 CAR24716.1 - 0.00052 19.8 4.2 0.00052 19.8 2.9 3.2 3 1 0 3 3 3 1 Tropomyosin like PsbH PF00737.15 CAR24716.1 - 0.0034 16.9 0.5 0.0061 16.1 0.4 1.3 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein Tropomyosin PF00261.15 CAR24716.1 - 0.027 13.5 20.0 0.031 13.3 8.3 2.5 1 1 1 2 2 2 0 Tropomyosin Phi-29_GP16_7 PF06720.6 CAR24716.1 - 0.036 13.7 0.3 0.09 12.4 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 ApoO PF09769.4 CAR24716.1 - 0.074 12.7 0.3 0.25 11.0 0.2 1.9 1 0 0 1 1 1 0 Apolipoprotein O Med9 PF07544.8 CAR24716.1 - 0.19 11.4 3.9 6.7 6.5 0.0 3.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spectrin PF00435.16 CAR24716.1 - 0.55 10.5 8.0 1.7 9.0 0.7 3.3 3 0 0 3 3 3 0 Spectrin repeat PIN_2 PF10130.4 CAR24716.1 - 3.6 7.6 7.1 3.8 7.5 0.1 3.3 3 1 0 3 3 3 0 PIN domain TPR_MLP1_2 PF07926.7 CAR24716.1 - 3.9 7.2 14.9 8.6 6.1 0.5 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 CAR24716.1 - 9.4 6.2 17.5 4.8 7.1 7.1 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA PF00004.24 CAR24717.1 - 6.8e-46 155.7 0.5 1.9e-45 154.2 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CAR24717.1 - 1.5e-08 34.7 0.0 3.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CAR24717.1 - 2.1e-07 30.7 0.2 1e-06 28.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR24717.1 - 1.7e-06 28.1 0.1 1.1e-05 25.5 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAR24717.1 - 3.9e-06 27.0 1.6 8.4e-05 22.7 0.3 2.7 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CAR24717.1 - 0.0001 23.1 0.1 0.00036 21.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 CAR24717.1 - 0.00012 21.0 0.0 0.00021 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CAR24717.1 - 0.00016 20.7 0.0 0.00046 19.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CAR24717.1 - 0.00047 20.0 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CAR24717.1 - 0.00084 18.1 0.0 0.0015 17.2 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 CAR24717.1 - 0.0016 18.1 0.1 0.0042 16.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CAR24717.1 - 0.002 18.0 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR24717.1 - 0.0022 17.1 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 CAR24717.1 - 0.0022 17.7 0.0 0.0068 16.1 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 CAR24717.1 - 0.0025 17.4 0.0 0.0072 15.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CAR24717.1 - 0.0028 17.8 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 CAR24717.1 - 0.003 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CAR24717.1 - 0.0033 16.8 0.1 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.1 CAR24717.1 - 0.0038 16.8 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CAR24717.1 - 0.0041 16.7 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CAR24717.1 - 0.0043 16.9 0.0 0.0089 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAR24717.1 - 0.0049 16.2 0.7 0.097 12.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 CAR24717.1 - 0.0058 16.3 0.1 0.065 12.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 CAR24717.1 - 0.0069 15.8 0.0 0.35 10.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CAR24717.1 - 0.007 15.5 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CAR24717.1 - 0.014 15.7 0.0 0.042 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 CAR24717.1 - 0.014 15.7 0.8 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAR24717.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CAR24717.1 - 0.036 13.7 2.1 0.12 12.0 0.0 2.6 3 1 0 4 4 3 0 Archaeal ATPase AFG1_ATPase PF03969.11 CAR24717.1 - 0.051 12.3 0.1 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase NB-ARC PF00931.17 CAR24717.1 - 0.083 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 CAR24717.1 - 0.19 10.5 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_transf_22 PF03901.12 CAR24718.1 - 2.5e-67 227.7 26.5 3e-67 227.4 18.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2142 PF09913.4 CAR24718.1 - 0.0047 15.6 15.6 0.0036 16.0 9.7 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2142) IBN_N PF03810.14 CAR24719.1 - 2.7e-13 49.6 0.2 9e-13 47.9 0.2 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.5 CAR24719.1 - 0.0002 20.0 0.2 0.0002 20.0 0.1 3.6 2 2 1 4 4 4 1 Cse1 Telomerase_RBD PF12009.3 CAR24719.1 - 0.0081 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain CBFD_NFYB_HMF PF00808.18 CAR24720.1 - 1.3e-14 54.0 2.2 2.1e-14 53.3 1.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rep_fac_C PF08542.6 CAR24720.1 - 0.1 12.5 0.3 0.24 11.3 0.3 1.5 2 0 0 2 2 2 0 Replication factor C C-terminal domain Terminase_2 PF03592.11 CAR24720.1 - 0.52 10.6 4.5 2.1 8.6 0.7 2.1 1 1 1 2 2 2 0 Terminase small subunit Utp12 PF04003.7 CAR24722.1 - 4.7e-21 74.7 0.6 7.9e-21 74.0 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family RAB3GAP2_N PF14655.1 CAR24722.1 - 0.023 13.7 0.0 0.052 12.5 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.27 CAR24722.1 - 0.084 12.7 0.0 5 7.1 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Pribosyltran PF00156.22 CAR24723.1 - 3.4e-11 42.9 0.1 1.1e-10 41.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain 3Beta_HSD PF01073.14 CAR24723.1 - 0.0022 16.7 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fe-ADH PF00465.14 CAR24723.1 - 0.017 13.8 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase MFS_1 PF07690.11 CAR24724.1 - 6e-21 74.5 93.3 1e-15 57.3 38.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily IU_nuc_hydro PF01156.14 CAR24726.1 - 1.6e-76 257.5 0.0 1.8e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.17 CAR24727.1 - 6.4e-47 160.1 0.1 2.8e-46 158.0 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 CLU_N PF15044.1 CAR24727.1 - 0.059 13.5 1.0 1.5 9.0 0.2 2.6 1 1 1 2 2 2 0 Mitochondrial function, CLU-N-term DIT1_PvcA PF05141.7 CAR24728.1 - 2.4e-97 325.5 0.0 3.2e-97 325.1 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein SHS2_Rpb7-N PF03876.12 CAR24729.1 - 7.6e-18 64.3 0.0 1.3e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CAR24729.1 - 1e-11 44.7 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 CAR24729.1 - 6.7e-05 23.0 0.0 0.00014 22.0 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.13 CAR24730.1 - 3.5e-44 149.9 0.3 4.2e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.23 CAR24731.1 - 8.2e-125 416.5 0.0 1.5e-124 415.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CAR24731.1 - 5.1e-68 228.0 0.1 8.4e-68 227.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CAR24731.1 - 3.2e-51 173.4 0.0 6e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CAR24731.1 - 1.5e-30 105.2 0.1 3.5e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CAR24731.1 - 4.1e-28 96.9 0.6 9.6e-28 95.7 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CAR24731.1 - 5.3e-22 77.3 0.1 1.8e-21 75.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CAR24731.1 - 1.9e-17 62.9 2.6 4.9e-17 61.6 1.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L23 PF00276.15 CAR24732.1 - 1.2e-21 76.4 0.5 4.1e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L23 ISN1 PF06437.6 CAR24734.1 - 3.5e-171 569.4 0.0 3.9e-171 569.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Choline_transpo PF04515.7 CAR24735.1 - 5.9e-94 314.5 23.3 5.9e-94 314.5 16.1 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4487 PF14868.1 CAR24735.1 - 0.14 10.7 0.4 0.54 8.9 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) Xpo1 PF08389.7 CAR24736.1 - 2e-25 89.4 1.0 2e-25 89.4 0.7 3.0 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 CAR24736.1 - 2.8e-05 23.9 1.4 0.0001 22.1 0.5 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain LSM PF01423.17 CAR24737.1 - 3.4e-14 52.1 0.0 4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4578 PF15147.1 CAR24738.1 - 0.13 12.6 1.8 0.21 11.9 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4578) TRAPPC9-Trs120 PF08626.6 CAR24739.1 - 2.6e-240 800.1 12.3 3.1e-240 799.9 8.5 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF2816 PF10992.3 CAR24739.1 - 0.15 11.6 0.9 3.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2816) Proteasome PF00227.21 CAR24740.1 - 8.5e-45 152.3 0.0 1.1e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CAR24740.1 - 1.1e-15 56.5 0.1 2.4e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Formyl_trans_N PF00551.14 CAR24741.1 - 1.7e-50 171.1 0.0 1.9e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase PINIT PF14324.1 CAR24742.1 - 3.3e-37 127.7 0.0 6e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 CAR24742.1 - 1.3e-18 66.2 11.0 2.2e-18 65.5 7.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 CAR24742.1 - 8.3e-09 34.7 0.2 1.6e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 CAR24742.1 - 0.0033 16.9 3.2 0.0069 15.8 2.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CAR24742.1 - 0.27 10.9 5.1 0.2 11.4 1.1 2.6 2 1 1 3 3 3 0 RING-type zinc-finger ICMT PF04140.9 CAR24743.1 - 1.5e-28 98.7 0.7 3e-28 97.8 0.5 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CAR24743.1 - 2.6e-15 56.4 3.0 2.6e-15 56.4 2.1 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 CAR24743.1 - 0.00036 19.9 1.2 0.00054 19.3 0.8 1.2 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.7 CAR24743.1 - 0.0073 15.6 3.2 0.0098 15.2 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) zf-HIT PF04438.11 CAR24744.1 - 0.00071 19.1 8.7 0.0012 18.3 6.0 1.3 1 0 0 1 1 1 1 HIT zinc finger Secretin_N_2 PF07655.8 CAR24744.1 - 0.28 11.5 9.2 0.81 10.1 1.0 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Carn_acyltransf PF00755.15 CAR24745.1 - 1.9e-179 597.6 0.1 2.2e-179 597.4 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DER1 PF04511.10 CAR24746.1 - 3.4e-35 121.3 12.9 4.6e-35 120.9 8.9 1.1 1 0 0 1 1 1 1 Der1-like family DUF2104 PF09877.4 CAR24746.1 - 0.025 14.5 1.9 0.15 12.0 0.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2104) Gate PF07670.9 CAR24746.1 - 0.069 13.0 1.4 0.14 12.1 1.0 1.4 1 0 0 1 1 1 0 Nucleoside recognition Nop25 PF09805.4 CAR24747.1 - 1.5e-36 125.5 21.9 1.5e-36 125.5 15.2 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) EXS PF03124.9 CAR24748.1 - 3.4e-67 226.9 18.4 3.9e-67 226.7 12.7 1.0 1 0 0 1 1 1 1 EXS family Transp_cyt_pur PF02133.10 CAR24749.1 - 2.9e-159 530.3 36.4 3.4e-159 530.1 25.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 CAR24750.1 - 1.7e-18 66.4 78.8 2.5e-13 49.4 35.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CAR24750.1 - 1.1 9.0 8.3 1.9 8.3 0.1 3.9 4 1 0 4 4 4 0 MFS_1 like family MLANA PF14991.1 CAR24750.1 - 1.2 9.1 3.4 8 6.5 0.1 3.0 3 0 0 3 3 3 0 Protein melan-A Ribosomal_L2_C PF03947.13 CAR24751.1 - 6.9e-49 164.9 0.9 1.4e-48 163.9 0.7 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CAR24751.1 - 9.4e-28 95.9 0.1 9.4e-28 95.9 0.1 2.2 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain ATP-synt_D PF01813.12 CAR24752.1 - 8.5e-65 217.9 5.0 8.5e-65 217.9 3.5 1.6 1 1 1 2 2 2 1 ATP synthase subunit D RICH PF05062.7 CAR24752.1 - 0.016 15.3 1.7 0.016 15.3 1.2 2.2 2 0 0 2 2 2 0 RICH domain Allexi_40kDa PF05549.6 CAR24752.1 - 0.21 10.8 4.3 0.5 9.6 1.8 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein APC_CDC26 PF10471.4 CAR24752.1 - 0.28 11.9 7.5 0.67 10.7 5.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 HET PF06985.6 CAR24752.1 - 0.67 10.1 3.2 1.5 8.9 1.0 2.3 2 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) TPR_14 PF13428.1 CAR24753.1 - 3.4e-13 48.9 1.8 0.18 12.5 0.0 8.5 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR24753.1 - 3e-09 36.0 4.5 0.19 11.6 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 CAR24753.1 - 1.4e-07 30.8 4.2 0.0036 16.4 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAR24753.1 - 1.4e-07 30.9 3.9 0.13 11.9 0.0 6.4 6 0 0 6 6 6 1 TPR repeat TPR_12 PF13424.1 CAR24753.1 - 1.2e-06 28.3 14.0 0.016 15.1 0.0 6.9 6 3 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 CAR24753.1 - 7e-06 25.9 0.4 2.6 7.6 0.0 4.3 6 0 0 6 6 6 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CAR24753.1 - 3.1e-05 24.2 0.0 8.6 6.7 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR24753.1 - 3.1e-05 23.3 4.2 0.095 12.3 0.0 5.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAR24753.1 - 4e-05 23.7 1.4 0.61 10.6 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR24753.1 - 0.00018 22.0 6.2 3.4 8.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR24753.1 - 0.00023 21.1 0.2 13 6.2 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR24753.1 - 0.00031 20.2 1.4 4.5 7.2 0.0 5.8 5 1 0 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CAR24753.1 - 0.0091 15.7 15.6 1.9 8.2 0.3 6.0 6 1 1 7 7 7 3 Mad3/BUB1 homology region 1 NRDE-2 PF08424.5 CAR24753.1 - 1.8 7.3 16.4 3.5 6.4 0.3 5.4 3 2 2 5 5 5 0 NRDE-2, necessary for RNA interference IMS PF00817.15 CAR24754.1 - 1e-43 148.6 0.0 1.7e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CAR24754.1 - 3.9e-10 39.7 0.0 8.8e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf-C2H2_jaz PF12171.3 CAR24754.1 - 0.067 13.3 0.1 0.19 11.9 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CAR24754.1 - 0.077 13.2 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ACBP PF00887.14 CAR24755.1 - 1.6e-22 78.9 0.0 2.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2890 PF11081.3 CAR24755.1 - 0.0047 17.0 0.6 0.082 12.9 0.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2890) Ribosomal_L11_N PF03946.9 CAR24756.1 - 5.5e-17 60.9 0.2 1.1e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CAR24756.1 - 1.9e-11 43.8 1.5 2.2e-11 43.7 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Mak10 PF04112.8 CAR24757.1 - 3.7e-43 146.6 0.0 6.4e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AFG1_ATPase PF03969.11 CAR24758.1 - 8.2e-78 261.7 0.1 2.6e-73 246.9 0.0 2.8 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 CAR24758.1 - 1.2e-05 25.4 1.2 0.0039 17.1 0.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CAR24758.1 - 0.00045 20.4 0.0 0.00085 19.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR24758.1 - 0.002 18.2 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAR24758.1 - 0.0029 17.5 0.1 0.015 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CAR24758.1 - 0.0044 16.7 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF1911 PF08929.5 CAR24758.1 - 0.036 14.7 0.3 0.081 13.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) NACHT PF05729.7 CAR24758.1 - 0.038 13.6 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 CAR24758.1 - 0.05 13.2 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 CAR24758.1 - 0.1 12.7 0.0 0.49 10.5 0.0 2.1 2 1 1 3 3 3 0 RNA helicase DUF1352 PF07086.7 CAR24759.1 - 0.63 9.6 0.2 1.2 8.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) Zn_clus PF00172.13 CAR24760.1 - 1.6e-07 31.1 10.2 3e-07 30.2 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CAR24760.1 - 0.0012 17.7 3.5 0.012 14.4 2.4 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.7 CAR24760.1 - 0.57 10.3 9.3 1.5 9.0 1.0 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region AMPKBI PF04739.10 CAR24762.1 - 4.7e-26 90.5 0.1 3.5e-25 87.8 0.0 2.5 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain PAP1 PF08601.5 CAR24763.1 - 1.8e-43 149.5 16.2 1.8e-43 149.5 11.3 3.9 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 CAR24763.1 - 2.5e-05 24.1 12.8 2.5e-05 24.1 8.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor Vpu PF00558.14 CAR24763.1 - 0.058 12.9 3.9 0.13 11.8 2.7 1.6 1 0 0 1 1 1 0 Vpu protein bZIP_2 PF07716.10 CAR24763.1 - 0.38 10.6 21.2 2.3 8.1 14.7 2.2 1 1 0 1 1 1 0 Basic region leucine zipper DUF4404 PF14357.1 CAR24763.1 - 0.57 10.6 4.5 0.56 10.6 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Adeno_PIX PF03955.9 CAR24763.1 - 7.3 7.1 8.8 1.7 9.2 2.2 2.6 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Sterol_MT_C PF08498.5 CAR24764.1 - 4.6e-30 103.3 2.1 6.8e-30 102.8 1.5 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CAR24764.1 - 1.6e-19 70.1 0.0 3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR24764.1 - 2.6e-17 62.8 0.0 3.8e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CAR24764.1 - 2.6e-14 52.9 0.1 3.7e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CAR24764.1 - 9.7e-13 48.1 0.0 1.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR24764.1 - 1.9e-12 47.4 0.1 5.8e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR24764.1 - 4.3e-12 46.2 0.0 9.5e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR24764.1 - 4.2e-11 43.4 0.0 9.3e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR24764.1 - 2.4e-08 33.9 0.0 6.1e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR24764.1 - 2.4e-08 33.3 0.0 4.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 CAR24764.1 - 3.9e-07 29.7 0.2 7.8e-07 28.7 0.1 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 CAR24764.1 - 0.0022 17.1 0.1 0.005 16.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 CAR24764.1 - 0.0049 16.4 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 CAR24764.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 CAR24764.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 CAR24764.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 CAR24764.1 - 0.085 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sugar_tr PF00083.19 CAR24765.1 - 4.6e-24 84.8 37.1 1.2e-19 70.2 25.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR24765.1 - 6.3e-18 64.6 44.1 6.5e-09 34.9 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CAR24765.1 - 0.00015 20.4 22.3 0.00093 17.7 1.0 2.5 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like Kinesin PF00225.18 CAR24766.1 - 3.3e-105 351.4 0.7 3.3e-105 351.4 0.5 1.4 2 0 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 CAR24766.1 - 0.28 11.3 2.0 0.96 9.5 0.1 2.8 2 2 1 3 3 3 0 AAA domain Dynein_light PF01221.13 CAR24767.1 - 2.1e-33 114.1 0.1 2.3e-33 114.0 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PX PF00787.19 CAR24768.1 - 5.2e-14 52.0 0.8 1.6e-13 50.4 0.1 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CAR24768.1 - 4.4e-06 26.1 7.2 4.4e-06 26.1 5.0 2.1 2 0 0 2 2 2 1 Vps5 C terminal like Spore_III_AB PF09548.5 CAR24768.1 - 0.049 13.3 0.2 0.049 13.3 0.1 2.8 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF479 PF04336.7 CAR24768.1 - 0.18 11.8 6.2 0.66 10.1 0.4 3.6 4 0 0 4 4 4 0 Protein of unknown function, DUF479 FliD_N PF02465.13 CAR24768.1 - 8.9 6.7 9.3 0.72 10.2 0.7 2.9 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus PCI PF01399.22 CAR24769.1 - 2.2e-12 47.2 0.0 7.1e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain Glyco_transf_7N PF13733.1 CAR24769.1 - 0.011 15.0 0.0 0.029 13.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Abhydrolase_3 PF07859.8 CAR24770.1 - 1.9e-09 37.4 0.0 2.3e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CAR24770.1 - 8.3e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR24770.1 - 1.9e-06 27.7 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 CAR24770.1 - 0.0087 14.7 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Rad60-SLD PF11976.3 CAR24770.1 - 0.01 15.5 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Abhydrolase_1 PF00561.15 CAR24770.1 - 0.019 14.5 0.0 0.057 12.9 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 CAR24770.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 CAR24770.1 - 0.025 13.7 0.1 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF900 PF05990.7 CAR24770.1 - 0.047 13.0 0.2 0.41 9.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) eIF3g PF12353.3 CAR24771.1 - 1.8e-47 160.4 1.1 2.8e-47 159.8 0.8 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CAR24771.1 - 4.1e-12 45.5 0.0 9.9e-12 44.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24771.1 - 3.2e-09 36.6 0.0 6.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24771.1 - 6.1e-08 32.3 0.0 1.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L33 PF00471.15 CAR24772.1 - 0.0016 18.6 0.0 0.0076 16.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L33 Spt5-NGN PF03439.8 CAR24773.1 - 3.9e-21 74.6 0.0 8.4e-21 73.5 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 CAR24773.1 - 3.1e-18 66.1 12.6 3.1e-18 66.1 8.7 4.0 2 1 2 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 CAR24773.1 - 3.5e-14 51.8 12.5 0.0013 18.3 0.1 4.7 4 0 0 4 4 4 4 KOW motif SPT6_acidic PF14632.1 CAR24773.1 - 0.011 15.8 18.0 0.011 15.8 12.5 3.6 1 1 2 3 3 3 0 Acidic N-terminal SPT6 Nucleo_P87 PF07267.6 CAR24773.1 - 0.11 11.2 22.8 0.21 10.2 15.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rad33 PF08730.5 CAR24775.1 - 6.5e-38 129.8 3.4 7.2e-24 84.1 0.3 2.1 1 1 1 2 2 2 2 Rad33 SpoVIF PF14069.1 CAR24775.1 - 0.021 14.5 0.0 0.21 11.3 0.0 2.4 2 1 0 2 2 2 0 Stage VI sporulation protein F EMP24_GP25L PF01105.19 CAR24776.1 - 2.8e-42 144.4 0.0 3.4e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pox_A32 PF04665.7 CAR24776.1 - 0.052 12.8 0.0 0.12 11.7 0.0 1.5 1 1 1 2 2 2 0 Poxvirus A32 protein M16C_assoc PF08367.6 CAR24777.1 - 2.2e-73 246.1 0.0 3.6e-73 245.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 CAR24777.1 - 4.1e-27 95.0 0.8 2.8e-15 56.4 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CAR24777.1 - 7.8e-07 28.9 0.0 2.7e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RRM_1 PF00076.17 CAR24778.1 - 7e-28 96.0 0.4 1.2e-16 60.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR24778.1 - 1.3e-16 60.2 0.1 1.7e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR24778.1 - 1.6e-11 43.8 0.0 2.9e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CAR24778.1 - 0.039 13.9 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain UBX PF00789.15 CAR24779.1 - 6.1e-14 51.8 0.0 1.3e-11 44.3 0.0 3.1 2 1 0 2 2 2 1 UBX domain UBA_4 PF14555.1 CAR24779.1 - 4.6e-09 35.6 0.0 1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DDHD PF02862.12 CAR24779.1 - 0.17 11.6 4.4 0.27 11.0 3.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF1993 PF09351.5 CAR24779.1 - 3.1 7.7 7.6 1.8 8.4 3.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Methyltransf_11 PF08241.7 CAR24780.1 - 1.9e-12 47.5 0.0 4.2e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR24780.1 - 9.1e-06 25.3 0.0 1.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR24780.1 - 9.8e-06 25.3 0.1 3.8e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR24780.1 - 3.6e-05 24.1 0.7 9.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR24780.1 - 6.1e-05 23.3 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR24780.1 - 0.0006 20.3 0.3 0.0015 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MRP-L28 PF09812.4 CAR24780.1 - 0.061 13.1 4.0 0.13 12.0 2.8 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 PIG-S PF10510.4 CAR24781.1 - 7.3e-131 437.3 1.8 9.4e-131 436.9 1.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.9 CAR24782.1 - 1.4e-25 88.9 2.4 1e-23 82.8 1.1 2.8 3 0 0 3 3 3 2 hTAFII28-like protein conserved region Rb_C PF08934.5 CAR24782.1 - 0.084 12.5 0.2 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Rb C-terminal domain LCM PF04072.9 CAR24783.1 - 2.9e-24 85.6 0.0 3.8e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Metallophos PF00149.23 CAR24784.1 - 4.5e-39 133.9 0.3 6.7e-39 133.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PIG-P PF08510.7 CAR24785.1 - 4.2e-36 123.3 1.8 5e-36 123.1 1.2 1.1 1 0 0 1 1 1 1 PIG-P EamA PF00892.15 CAR24787.1 - 1.3e-09 38.1 26.2 5.6e-08 32.8 2.8 4.1 3 2 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 CAR24787.1 - 2.2e-07 30.6 28.6 5.7e-05 22.8 5.7 3.3 3 1 1 4 4 4 2 Triose-phosphate Transporter family UAA PF08449.6 CAR24787.1 - 0.00012 21.0 12.2 0.00012 21.0 8.5 1.9 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 CAR24787.1 - 0.00058 20.0 2.3 0.00058 20.0 1.6 4.0 3 1 1 4 4 4 2 Multidrug resistance efflux transporter DUF914 PF06027.7 CAR24787.1 - 1.5 7.5 15.5 1.7 7.4 7.0 2.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) OST3_OST6 PF04756.8 CAR24788.1 - 1.9e-18 66.5 8.2 3.5e-18 65.6 5.7 1.4 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 CAR24788.1 - 0.0025 17.4 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin LRS4 PF10422.4 CAR24789.1 - 4.5e-20 72.0 30.8 1.7e-15 57.0 9.6 3.5 1 1 1 2 2 2 2 Monopolin complex subunit LRS4 DUF3573 PF12097.3 CAR24789.1 - 0.015 13.9 0.4 0.026 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TSC22 PF01166.13 CAR24789.1 - 0.68 9.9 7.4 0.13 12.1 2.2 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Abhydrolase_5 PF12695.2 CAR24790.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UDG PF03167.14 CAR24791.1 - 4e-22 78.3 0.0 5.4e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DOT1 PF08123.8 CAR24792.1 - 1.4e-85 285.7 0.0 2.1e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pribosyltran PF00156.22 CAR24793.1 - 3.7e-15 55.7 0.0 5.1e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CAR24793.1 - 0.0085 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Nse5 PF08691.5 CAR24794.1 - 3.3e-150 500.9 0.6 3.9e-150 500.7 0.4 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 DUF3469 PF11952.3 CAR24794.1 - 0.031 13.9 0.1 0.38 10.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3469) Med13_C PF06333.7 CAR24795.1 - 2e-85 286.8 7.5 5.9e-55 186.5 0.3 2.8 2 1 1 3 3 3 2 Mediator complex subunit 13 C-terminal DUF676 PF05057.9 CAR24796.1 - 6.9e-44 149.7 0.0 1.1e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.6 CAR24796.1 - 0.005 15.9 0.1 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CAR24796.1 - 0.035 13.7 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) FAD-oxidase_C PF02913.14 CAR24797.1 - 2.1e-43 148.4 0.0 3.1e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CAR24797.1 - 1.9e-37 127.8 0.2 3.5e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain ECM11 PF15463.1 CAR24798.1 - 1.3e-29 103.2 0.0 1.3e-29 103.2 0.0 2.7 2 1 1 3 3 3 1 Extracellular mutant protein 11 Ribosomal_S17e PF00833.13 CAR24799.1 - 3.6e-56 188.1 0.4 4.3e-56 187.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 ZZ PF00569.12 CAR24800.1 - 2.9e-16 58.7 8.0 5e-16 57.9 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 CAR24800.1 - 2.6e-10 40.2 0.0 3.4e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 CAR24800.1 - 6.1e-08 32.5 0.1 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR24800.1 - 0.00089 19.3 0.1 0.0034 17.4 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain U3_assoc_6 PF08640.6 CAR24801.1 - 5.2e-32 109.4 7.3 1.1e-30 105.2 1.6 2.9 2 1 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 CAR24801.1 - 1.1e-05 24.4 6.0 0.016 14.0 1.3 2.4 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.9 CAR24801.1 - 0.00025 20.8 7.6 0.0012 18.6 1.6 3.7 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CAR24801.1 - 0.0032 17.9 0.0 2.8 8.8 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR24801.1 - 0.095 12.9 0.0 39 4.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L4 PF00573.17 CAR24802.1 - 1.3e-45 155.2 0.0 1.5e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S13 PF00416.17 CAR24803.1 - 8e-42 142.0 1.9 9.3e-42 141.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CAR24803.1 - 0.00059 18.5 0.1 0.00099 17.7 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Homeobox PF00046.24 CAR24804.1 - 2.9e-17 62.0 4.1 6.8e-17 60.8 2.8 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CAR24804.1 - 0.00016 21.2 0.7 0.0015 18.2 0.1 2.5 2 0 0 2 2 2 1 Homeobox KN domain Metallophos PF00149.23 CAR24805.1 - 1.7e-12 47.1 0.5 2.7e-12 46.4 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FeoA PF04023.9 CAR24805.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 FeoA domain BLVR PF06375.6 CAR24805.1 - 0.066 13.0 4.5 0.14 12.0 3.1 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Gln-synt_N PF03951.14 CAR24805.1 - 0.1 12.2 0.1 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain AhpC-TSA PF00578.16 CAR24806.1 - 2e-34 117.9 0.0 5.7e-34 116.4 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CAR24806.1 - 2.2e-19 69.4 0.0 3.3e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CAR24806.1 - 4e-12 45.5 0.2 8.1e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Rad60-SLD_2 PF13881.1 CAR24807.1 - 0.00095 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CAR24807.1 - 0.01 15.1 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family HIG_1_N PF04588.8 CAR24808.1 - 4.3e-22 77.6 1.3 5.7e-22 77.2 0.9 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2514 PF10721.4 CAR24808.1 - 0.031 13.9 12.9 0.016 14.9 6.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2514) OmpH PF03938.9 CAR24808.1 - 0.048 13.5 7.8 0.067 13.1 5.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 CAR24808.1 - 0.39 11.0 5.3 0.43 10.8 3.7 1.2 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 CAR24808.1 - 9.1 4.5 10.6 11 4.2 7.3 1.1 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 CAR24809.1 - 5.3e-68 228.0 0.0 5.9e-68 227.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_22 PF13401.1 CAR24809.1 - 1.4e-06 28.5 0.0 2.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR24809.1 - 2.3e-05 24.2 0.0 9.9e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR24809.1 - 3.9e-05 23.7 0.0 8.3e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CAR24809.1 - 4.2e-05 24.3 0.0 7.8e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR24809.1 - 4.7e-05 23.7 0.0 0.00017 21.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CAR24809.1 - 0.00031 20.6 0.1 0.00088 19.2 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CAR24809.1 - 0.0005 20.2 0.0 0.00083 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 CAR24809.1 - 0.00059 20.0 0.2 0.0045 17.1 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CAR24809.1 - 0.00068 19.5 0.0 0.00091 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CAR24809.1 - 0.0009 18.2 0.1 0.0045 15.9 0.0 2.0 1 1 1 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 CAR24809.1 - 0.0012 19.3 0.0 0.0026 18.2 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 CAR24809.1 - 0.0014 18.3 0.1 0.0016 18.1 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 CAR24809.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CAR24809.1 - 0.0015 17.7 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CAR24809.1 - 0.0022 18.3 0.1 0.0028 17.9 0.1 1.4 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 CAR24809.1 - 0.0027 17.3 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 CAR24809.1 - 0.0054 16.2 0.2 0.013 14.9 0.0 1.7 2 1 0 2 2 2 1 AAA-like domain NTPase_1 PF03266.10 CAR24809.1 - 0.0059 16.3 0.1 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 NTPase AAA_19 PF13245.1 CAR24809.1 - 0.0073 16.0 0.0 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 CAR24809.1 - 0.0099 14.8 0.0 0.025 13.5 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 CAR24809.1 - 0.015 15.0 0.1 0.04 13.6 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 CAR24809.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 CAR24809.1 - 0.017 14.1 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 CAR24809.1 - 0.019 14.4 2.1 0.022 14.2 0.2 1.9 2 1 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.10 CAR24809.1 - 0.025 13.2 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 CAR24809.1 - 0.029 13.9 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CAR24809.1 - 0.034 13.5 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 CAR24809.1 - 0.037 13.6 0.6 0.068 12.7 0.4 1.8 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 CAR24809.1 - 0.04 13.1 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_23 PF13476.1 CAR24809.1 - 0.045 14.0 1.1 0.052 13.8 0.7 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CAR24809.1 - 0.049 12.4 0.0 0.098 11.4 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 CAR24809.1 - 0.14 11.9 0.2 0.3 10.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Na_H_Exchanger PF00999.16 CAR24810.1 - 1.2e-64 218.1 38.3 1.6e-64 217.8 26.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.1 CAR24810.1 - 0.074 12.6 4.9 0.077 12.5 1.1 2.4 2 0 0 2 2 2 0 Myc target protein 1 Ndc1_Nup PF09531.5 CAR24811.1 - 2.4e-111 373.0 1.8 5.2e-111 371.9 1.2 1.5 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TMEM125 PF15109.1 CAR24811.1 - 0.2 11.8 5.0 0.18 11.9 0.4 2.5 2 0 0 2 2 2 0 TMEM125 protein family Rad52_Rad22 PF04098.10 CAR24812.1 - 2e-55 186.7 0.0 2.9e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein HECT PF00632.20 CAR24813.1 - 1.1e-91 307.3 0.1 1.1e-91 307.3 0.1 3.1 4 0 0 4 4 4 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 CAR24813.1 - 1.6e-74 251.1 4.7 5.7e-74 249.3 1.3 2.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 CAR24813.1 - 8.2e-42 143.2 1.0 2.8e-41 141.5 0.0 2.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 CAR24813.1 - 6.5e-16 58.1 1.2 6.5e-16 58.1 0.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) DUF1858 PF08984.6 CAR24813.1 - 0.016 14.8 0.4 4.8 6.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1858) MSC PF09402.5 CAR24815.1 - 4.6e-104 347.7 4.1 4.6e-104 347.7 2.9 1.7 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CAR24815.1 - 1.5e-15 56.4 2.1 1.7e-15 56.2 0.1 2.3 2 0 0 2 2 2 1 HeH/LEM domain 60KD_IMP PF02096.15 CAR24815.1 - 0.025 14.2 1.0 0.36 10.4 0.5 2.3 2 0 0 2 2 2 0 60Kd inner membrane protein SAP PF02037.22 CAR24815.1 - 0.065 12.7 0.1 0.065 12.7 0.1 2.3 2 0 0 2 2 2 0 SAP domain A_deaminase PF00962.17 CAR24816.1 - 3.9e-117 390.8 0.2 7.9e-117 389.8 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase zf-DHHC PF01529.15 CAR24817.1 - 5e-30 104.1 0.3 8.9e-30 103.3 0.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase MAT1 PF06391.8 CAR24818.1 - 8.7e-60 201.7 24.9 1.1e-59 201.4 17.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 CAR24818.1 - 0.0023 17.5 4.9 0.004 16.7 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR24818.1 - 0.0029 17.5 6.0 0.0079 16.2 4.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR24818.1 - 0.0061 16.2 5.3 0.023 14.3 3.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR24818.1 - 0.0072 16.1 5.8 0.014 15.1 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-piccolo PF05715.8 CAR24818.1 - 0.096 12.7 1.1 0.2 11.7 0.8 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_5 PF14634.1 CAR24818.1 - 0.11 12.2 9.2 0.91 9.3 6.3 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Spectrin PF00435.16 CAR24818.1 - 0.16 12.2 9.7 0.053 13.7 3.9 2.2 1 1 1 2 2 2 0 Spectrin repeat zf-RING_UBOX PF13445.1 CAR24818.1 - 0.38 10.4 4.0 0.98 9.1 2.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CAR24818.1 - 1 9.0 9.5 10 5.8 6.6 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CGI-121 PF08617.5 CAR24819.1 - 2.9e-34 118.0 0.0 3.4e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Crystall PF00030.14 CAR24819.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 2 0 0 2 2 2 0 Beta/Gamma crystallin MRP-L28 PF09812.4 CAR24821.1 - 4.4e-40 137.0 3.7 5.3e-40 136.8 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 FYRC PF05965.9 CAR24821.1 - 0.018 14.8 0.1 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 F/Y rich C-terminus TPT PF03151.11 CAR24822.1 - 1.5e-38 131.8 4.2 1.5e-38 131.8 2.9 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CAR24822.1 - 2.2e-12 46.5 10.1 3.8e-12 45.7 7.0 1.3 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CAR24822.1 - 1.9e-06 27.2 1.2 0.00014 21.0 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 CAR24822.1 - 1.5e-05 24.9 22.2 0.0097 15.9 6.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CAR24822.1 - 0.00057 20.0 6.7 0.00057 20.0 4.6 2.8 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 CAR24822.1 - 0.047 13.5 12.8 0.58 9.9 0.7 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 DUF485 PF04341.7 CAR24822.1 - 0.12 12.0 6.8 1.1 9.0 0.1 3.4 1 1 1 3 3 3 0 Protein of unknown function, DUF485 zf-H2C2_2 PF13465.1 CAR24823.1 - 0.0014 18.8 0.1 0.0014 18.8 0.1 3.9 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CAR24823.1 - 0.0019 18.4 15.0 0.0077 16.5 2.0 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR24823.1 - 0.0044 17.2 13.4 0.042 14.1 1.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-FCS PF06467.9 CAR24823.1 - 0.097 12.3 4.2 6.1 6.5 0.2 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 CAR24823.1 - 0.33 11.1 6.2 1.8 8.7 2.4 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CAR24823.1 - 0.99 9.2 14.8 0.35 10.6 2.7 2.9 2 1 1 3 3 3 0 BED zinc finger DUF3020 PF11223.3 CAR24824.1 - 1.6e-12 47.5 8.7 1.6e-12 47.5 6.0 8.0 8 0 0 8 8 8 2 Protein of unknown function (DUF3020) p450 PF00067.17 CAR24825.1 - 3.2e-102 342.4 0.0 3.8e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 CAR24826.1 - 0.064 13.7 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Sod_Fe_C PF02777.13 CAR24827.1 - 6.9e-37 125.5 0.2 1.4e-36 124.4 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CAR24827.1 - 1.4e-25 89.3 0.2 2.4e-25 88.5 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pkinase PF00069.20 CAR24828.1 - 3e-61 206.8 0.0 3.9e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24828.1 - 1.7e-29 102.6 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR24828.1 - 4e-09 35.8 0.0 6.3e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR24828.1 - 0.00043 20.0 0.0 0.0026 17.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR24828.1 - 0.00062 18.8 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAR24828.1 - 0.028 13.7 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DAO PF01266.19 CAR24829.1 - 1.9e-68 231.0 0.0 1.4e-46 159.0 0.0 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CAR24829.1 - 6.9e-07 29.1 0.0 2.7e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CAR24829.1 - 0.0039 16.3 0.1 0.0064 15.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CAR24829.1 - 0.0052 16.8 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR24829.1 - 0.0095 15.7 0.1 0.032 14.0 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF2201_N PF13203.1 CAR24829.1 - 0.021 14.0 4.0 0.032 13.4 2.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Pyr_redox PF00070.22 CAR24829.1 - 0.078 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 CAR24829.1 - 0.11 10.8 0.1 0.18 10.1 0.1 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Saccharop_dh PF03435.13 CAR24829.1 - 0.14 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase MFMR PF07777.6 CAR24829.1 - 0.89 9.4 4.7 1.6 8.6 3.3 1.4 1 0 0 1 1 1 0 G-box binding protein MFMR SNARE PF05739.14 CAR24830.1 - 2e-12 46.5 4.5 2e-12 46.5 3.1 3.1 4 0 0 4 4 4 1 SNARE domain IncA PF04156.9 CAR24830.1 - 9.7e-05 22.0 2.1 9.7e-05 22.0 1.5 2.9 2 1 1 3 3 3 1 IncA protein Sulfatase PF00884.18 CAR24830.1 - 0.0026 17.0 0.7 1.2 8.3 0.1 2.2 2 0 0 2 2 2 2 Sulfatase Sipho_Gp157 PF05565.6 CAR24830.1 - 0.0046 16.5 3.8 0.014 14.9 0.5 2.1 2 0 0 2 2 2 1 Siphovirus Gp157 Myosin_tail_1 PF01576.14 CAR24830.1 - 0.0053 14.5 7.7 0.0077 14.0 5.3 1.2 1 0 0 1 1 1 1 Myosin tail FlaC_arch PF05377.6 CAR24830.1 - 0.028 14.3 3.3 8 6.4 0.1 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RmuC PF02646.11 CAR24830.1 - 0.041 12.7 8.8 0.024 13.4 0.8 2.4 2 1 1 3 3 3 0 RmuC family Syntaxin-6_N PF09177.6 CAR24830.1 - 0.052 13.9 9.7 0.056 13.8 1.7 3.3 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Sec20 PF03908.8 CAR24830.1 - 0.059 13.0 1.4 0.1 12.3 0.2 1.9 2 1 0 2 2 2 0 Sec20 TMPIT PF07851.8 CAR24830.1 - 0.065 12.3 2.3 0.59 9.1 1.4 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF371 PF04027.8 CAR24830.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF371) Erp_C PF06780.6 CAR24830.1 - 0.12 12.2 4.6 0.32 10.8 0.4 2.2 2 0 0 2 2 2 0 Erp protein C-terminus Atg14 PF10186.4 CAR24830.1 - 0.15 10.9 5.6 0.23 10.3 3.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HisKA_3 PF07730.8 CAR24830.1 - 0.24 11.7 6.3 3.4 8.0 0.2 2.7 3 0 0 3 3 2 0 Histidine kinase Baculo_PEP_C PF04513.7 CAR24830.1 - 0.24 11.2 3.3 0.83 9.4 0.4 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CAR24830.1 - 0.26 11.5 3.2 2 8.7 0.2 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 CAR24830.1 - 0.31 11.3 8.7 1 9.7 0.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) SH3BP5 PF05276.9 CAR24830.1 - 0.44 9.8 7.9 0.37 10.0 0.6 2.1 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) DUF745 PF05335.8 CAR24830.1 - 0.91 9.0 6.6 1.7 8.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TMCO5 PF14992.1 CAR24830.1 - 1.1 8.3 9.1 0.24 10.4 3.2 1.8 1 1 0 2 2 2 0 TMCO5 family Rootletin PF15035.1 CAR24830.1 - 1.1 9.2 11.0 0.17 11.8 1.3 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF342 PF03961.8 CAR24830.1 - 1.3 7.3 3.9 6.2 5.1 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fzo_mitofusin PF04799.8 CAR24830.1 - 1.5 8.1 6.2 3.4 7.0 0.5 2.4 2 1 0 2 2 2 0 fzo-like conserved region Microtub_assoc PF07989.6 CAR24830.1 - 1.7 8.4 6.0 3 7.7 0.6 3.1 3 0 0 3 3 3 0 Microtubule associated Uds1 PF15456.1 CAR24830.1 - 1.8 8.5 8.2 2.9 7.8 2.6 2.4 2 1 0 2 2 2 0 Up-regulated During Septation DUF1664 PF07889.7 CAR24830.1 - 2.2 8.0 6.4 5.3 6.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 CAR24830.1 - 2.6 7.7 6.3 4.9 6.9 0.6 2.4 2 1 0 2 2 2 0 Laminin Domain II Nup88 PF10168.4 CAR24830.1 - 2.6 5.7 7.4 0.2 9.4 1.3 1.7 2 0 0 2 2 2 0 Nuclear pore component APG6 PF04111.7 CAR24830.1 - 2.9 6.8 8.5 4.9 6.1 1.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 SlyX PF04102.7 CAR24830.1 - 4.3 7.7 16.1 1.8 9.0 0.6 3.7 2 2 1 3 3 3 0 SlyX DUF1732 PF08340.6 CAR24830.1 - 5.3 6.9 7.8 10 6.0 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1732) Ribosomal_L29 PF00831.18 CAR24830.1 - 6.3 6.5 9.4 6.2 6.5 1.5 3.0 2 1 0 2 2 2 0 Ribosomal L29 protein IKKbetaNEMObind PF12179.3 CAR24830.1 - 8.6 6.2 8.1 24 4.8 0.1 3.7 4 0 0 4 4 4 0 I-kappa-kinase-beta NEMO binding domain Dpy-30 PF05186.8 CAR24831.1 - 3.4e-18 64.8 0.1 4.4e-18 64.4 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif Mito_carr PF00153.22 CAR24832.1 - 3.6e-09 36.1 0.0 0.017 14.8 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Rnk_N PF14760.1 CAR24833.1 - 0.0042 17.1 4.6 0.079 13.0 0.2 3.3 3 0 0 3 3 3 1 Rnk N-terminus DDHD PF02862.12 CAR24833.1 - 0.014 15.2 1.0 0.022 14.5 0.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF3166 PF11365.3 CAR24833.1 - 0.016 15.6 2.0 0.18 12.2 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) DUF755 PF05501.6 CAR24833.1 - 0.067 13.2 2.1 0.13 12.3 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FAM117 PF15388.1 CAR24833.1 - 0.67 9.1 3.8 0.48 9.6 1.7 1.5 1 1 1 2 2 2 0 Protein Family FAM117 SPT16 PF08644.6 CAR24833.1 - 0.69 9.7 3.6 0.4 10.4 0.2 2.2 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) IncA PF04156.9 CAR24833.1 - 0.76 9.3 14.5 0.95 9.0 2.1 2.1 2 0 0 2 2 2 0 IncA protein ADIP PF11559.3 CAR24833.1 - 1.6 8.5 18.0 1.1 9.1 2.5 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YscO PF07321.7 CAR24833.1 - 1.6 8.5 20.9 0.16 11.7 5.6 2.4 1 1 1 2 2 2 0 Type III secretion protein YscO FUSC PF04632.7 CAR24833.1 - 7.9 4.7 11.8 9.4 4.5 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L27e PF01777.13 CAR24834.1 - 9.6e-37 124.9 4.3 1.3e-36 124.5 2.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CAR24834.1 - 0.00026 20.5 2.2 0.00054 19.5 1.6 1.5 1 0 0 1 1 1 1 KOW motif DUF1512 PF07431.7 CAR24834.1 - 0.064 11.9 0.3 0.12 11.1 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) tRNA-synt_2b PF00587.20 CAR24835.1 - 1.6e-22 79.8 0.0 2.3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CAR24835.1 - 1.2e-05 25.2 5.5 2.1e-05 24.4 3.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.3 CAR24835.1 - 0.0049 14.2 3.1 0.0065 13.8 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) YPEB PF14620.1 CAR24835.1 - 0.055 12.4 4.2 0.091 11.7 2.9 1.2 1 0 0 1 1 1 0 YpeB sporulation Spc7 PF08317.6 CAR24835.1 - 0.096 11.3 6.4 0.15 10.7 4.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF342 PF03961.8 CAR24835.1 - 0.12 10.7 1.9 0.16 10.3 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PEARLI-4 PF05278.7 CAR24835.1 - 0.12 11.7 5.9 0.19 11.0 4.1 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) HAUS-augmin3 PF14932.1 CAR24835.1 - 0.33 10.0 8.0 0.51 9.4 5.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 CAR24835.1 - 0.41 10.2 13.6 0.032 13.8 6.0 1.6 2 0 0 2 2 2 0 IncA protein TMF_TATA_bd PF12325.3 CAR24835.1 - 2.1 8.0 13.0 0.16 11.7 5.6 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.9 CAR24835.1 - 5 6.7 9.7 10 5.6 6.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cep57_CLD_2 PF14197.1 CAR24835.1 - 5.6 6.9 11.5 12 5.9 8.0 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Metallophos_2 PF12850.2 CAR24836.1 - 3.1e-17 62.8 0.0 7.2e-17 61.6 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Acetyltransf_1 PF00583.19 CAR24837.1 - 9.1e-14 51.2 0.0 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CAR24837.1 - 1.8e-05 24.3 0.1 3.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CAR24837.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR24837.1 - 0.00022 21.2 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR24837.1 - 0.0071 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAR24837.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TRAPP PF04051.11 CAR24838.1 - 2e-43 147.5 0.0 2.6e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PSRT PF07636.6 CAR24839.1 - 0.0013 18.1 2.8 0.0013 18.1 1.9 2.3 2 0 0 2 2 2 1 PSRT DDHD PF02862.12 CAR24840.1 - 2.4e-45 155.1 4.4 7.4e-28 97.8 0.1 3.0 2 1 1 3 3 3 2 DDHD domain LCAT PF02450.10 CAR24840.1 - 5.6e-06 25.5 0.0 0.00046 19.2 0.0 2.2 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 CAR24840.1 - 0.0017 17.7 0.1 0.92 8.7 0.0 2.6 2 1 0 2 2 2 2 Putative serine esterase (DUF676) DUF2305 PF10230.4 CAR24840.1 - 0.011 15.2 0.1 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) RNA_Me_trans PF04252.8 CAR24841.1 - 1.3e-77 259.6 0.0 1.5e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF2611 PF11022.3 CAR24842.1 - 2.8e-15 56.1 0.3 3.6e-15 55.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Cpn10 PF00166.16 CAR24843.1 - 4.6e-27 93.7 0.0 5.2e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PRP3 PF08572.5 CAR24844.1 - 1.4e-55 188.0 15.6 2e-55 187.5 10.8 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CAR24844.1 - 4.8e-30 103.8 0.0 4.8e-30 103.8 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) Arf PF00025.16 CAR24846.1 - 5.8e-29 100.5 0.4 8.4e-28 96.7 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 CAR24846.1 - 5.3e-17 61.6 0.0 9.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR24846.1 - 6.4e-11 42.7 0.0 2.4e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CAR24846.1 - 2.1e-08 34.1 0.0 4.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAR24846.1 - 6.4e-08 32.0 0.0 1.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR24846.1 - 1.1e-06 28.2 0.0 0.00045 19.7 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CAR24846.1 - 1.9e-06 27.2 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CAR24846.1 - 3.5e-06 25.9 0.2 1.7e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 CAR24846.1 - 0.00061 19.6 0.2 0.13 12.0 0.1 2.4 1 1 1 2 2 2 2 Dynamin family ATP_bind_1 PF03029.12 CAR24846.1 - 0.087 12.3 0.1 0.43 10.0 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF2470 PF10615.4 CAR24847.1 - 1.7e-14 53.7 0.0 3.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) QCR10 PF09796.4 CAR24847.1 - 0.087 12.5 0.2 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pkinase PF00069.20 CAR24848.1 - 2.4e-76 256.3 0.0 3.6e-76 255.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24848.1 - 6.9e-38 130.2 0.0 1e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 CAR24848.1 - 2.1e-21 75.8 3.2 2.3e-21 75.7 0.8 2.2 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 CAR24848.1 - 8.1e-10 38.1 0.0 2.6e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CAR24848.1 - 3.2e-05 23.3 0.5 7.9e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 CAR24848.1 - 5.1e-05 22.0 0.2 0.0001 21.0 0.2 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 CAR24848.1 - 0.0022 17.7 0.2 0.41 10.3 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CAR24848.1 - 0.0027 16.8 0.1 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3918 PF13056.1 CAR24848.1 - 0.17 11.2 2.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) SIR2 PF02146.12 CAR24849.1 - 3.2e-34 118.2 0.0 4.2e-33 114.5 0.0 2.2 1 1 0 1 1 1 1 Sir2 family DUF573 PF04504.9 CAR24849.1 - 0.018 15.3 0.1 0.053 13.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 PX PF00787.19 CAR24850.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 PX domain Aldo_ket_red PF00248.16 CAR24852.1 - 6.9e-50 169.4 0.0 8.2e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 CAR24853.1 - 1.7e-71 236.0 0.4 4.2e-24 84.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF500 PF04366.7 CAR24853.1 - 0.01 15.2 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF500) Ribosomal_L37ae PF01780.14 CAR24854.1 - 1.6e-39 133.6 9.1 1.8e-39 133.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 CAR24854.1 - 0.006 16.2 0.3 0.0071 16.0 0.2 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain DUF1364 PF07102.7 CAR24854.1 - 0.0079 16.0 0.8 0.01 15.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) Zn_Tnp_IS1595 PF12760.2 CAR24854.1 - 0.011 15.4 3.1 0.018 14.8 2.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 CAR24854.1 - 0.016 15.4 0.8 0.89 9.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain OrfB_Zn_ribbon PF07282.6 CAR24854.1 - 0.019 14.6 1.4 0.026 14.1 0.9 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Sgf11 PF08209.6 CAR24854.1 - 0.021 14.1 0.5 0.31 10.3 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CarbpepA_inh PF02977.10 CAR24854.1 - 0.034 13.7 4.2 0.062 12.8 0.7 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-ribbon_3 PF13248.1 CAR24854.1 - 0.044 13.0 1.0 5.4 6.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 CAR24854.1 - 0.049 13.3 2.0 0.074 12.8 1.4 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 CAR24854.1 - 0.17 11.3 2.5 6.6 6.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 CAR24854.1 - 0.21 11.1 1.6 1.7 8.2 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 CAR24854.1 - 0.23 11.1 2.8 0.54 9.9 1.9 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.10 CAR24854.1 - 0.39 10.3 4.1 3.6 7.2 0.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C4_ClpX PF06689.8 CAR24854.1 - 8.6 5.9 9.1 79 2.8 6.5 2.2 1 1 1 2 2 2 0 ClpX C4-type zinc finger Med6 PF04934.9 CAR24856.1 - 8.5e-57 190.6 0.1 1.1e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component CoA_trans PF01144.18 CAR24856.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase Pro_isomerase PF00160.16 CAR24857.1 - 1.4e-44 152.0 0.1 1.7e-44 151.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AIM24 PF01987.12 CAR24858.1 - 1.2e-13 51.0 0.0 3.6e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 PIG-F PF06699.6 CAR24859.1 - 4.9e-40 137.5 16.5 3.4e-39 134.7 11.5 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.14 CAR24859.1 - 0.6 9.5 7.9 2 7.7 5.6 1.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE CPSF_A PF03178.10 CAR24860.1 - 3.9e-85 285.7 1.3 3.8e-84 282.5 0.1 3.0 3 1 1 4 4 4 1 CPSF A subunit region AA_kinase PF00696.23 CAR24861.1 - 2.5e-37 128.7 0.6 3.7e-37 128.1 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CAR24861.1 - 4.3e-20 71.2 0.1 1.1e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 PUA domain DUF4224 PF13986.1 CAR24861.1 - 0.077 12.5 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) PIH1 PF08190.7 CAR24862.1 - 4.8e-23 82.1 0.0 6.5e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 AATF-Che1 PF13339.1 CAR24863.1 - 2.6e-27 95.5 1.2 2.6e-27 95.5 0.8 2.5 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 CAR24863.1 - 2.4e-24 85.2 0.0 6.1e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal OSCP PF00213.13 CAR24864.1 - 9.9e-43 145.9 3.2 1.1e-42 145.7 2.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit KaiB PF07689.7 CAR24864.1 - 0.086 12.3 0.1 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiB domain FA_hydroxylase PF04116.8 CAR24865.1 - 3e-17 63.0 7.7 3e-17 63.0 5.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Mhr1 PF12829.2 CAR24866.1 - 5.2e-37 125.5 1.0 1.1e-36 124.4 0.4 1.8 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Peptidase_S13 PF02113.10 CAR24866.1 - 0.064 11.7 0.0 0.088 11.2 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Sec23_trunk PF04811.10 CAR24867.1 - 5.4e-12 45.5 0.0 1.9e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CAR24867.1 - 3e-07 30.8 0.3 7.7e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain EST1 PF10374.4 CAR24867.1 - 0.011 15.6 1.0 0.029 14.3 0.0 2.2 2 0 0 2 2 2 0 Telomerase activating protein Est1 zf-Sec23_Sec24 PF04810.10 CAR24867.1 - 1.9 8.1 6.8 0.88 9.1 2.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HDA2-3 PF11496.3 CAR24868.1 - 1.6e-71 240.5 0.4 1.6e-71 240.5 0.3 1.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Latarcin PF10279.4 CAR24868.1 - 0.46 10.6 7.6 0.42 10.8 4.0 2.0 1 1 0 1 1 1 0 Latarcin precursor Pyridoxal_deC PF00282.14 CAR24869.1 - 1.6e-25 89.3 0.0 4.7e-25 87.8 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CAR24869.1 - 3.6e-10 39.1 0.0 2.4e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CAR24869.1 - 5.9e-08 32.1 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SLA_LP_auto_ag PF05889.8 CAR24869.1 - 0.00014 20.4 0.0 0.00025 19.6 0.0 1.3 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Brr6_like_C_C PF10104.4 CAR24870.1 - 1.6e-43 147.4 0.3 3e-43 146.5 0.2 1.5 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Aldedh PF00171.17 CAR24871.1 - 6.4e-101 337.9 0.0 7.5e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNB PF00773.14 CAR24872.1 - 3.5e-59 200.7 0.5 8.6e-59 199.4 0.4 1.7 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 CAR24872.1 - 0.0026 17.2 0.1 1.6 8.2 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain RRF PF01765.14 CAR24873.1 - 1.8e-42 144.5 6.8 2.8e-42 144.0 4.7 1.3 1 0 0 1 1 1 1 Ribosome recycling factor NYD-SP28 PF14772.1 CAR24873.1 - 0.028 14.5 4.1 0.052 13.6 2.8 1.5 1 0 0 1 1 1 0 Sperm tail DNA_repr_REX1B PF14966.1 CAR24873.1 - 0.065 13.6 0.9 0.13 12.6 0.6 1.5 1 0 0 1 1 1 0 DNA repair REX1-B DUF922 PF06037.6 CAR24873.1 - 0.21 10.8 2.0 0.25 10.6 0.5 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) DASH_Duo1 PF08651.5 CAR24873.1 - 0.54 9.8 3.4 0.5 9.9 1.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF812 PF05667.6 CAR24873.1 - 0.59 8.5 10.0 0.058 11.9 3.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) IL31 PF15209.1 CAR24873.1 - 0.86 9.2 6.6 3.5 7.2 0.1 3.0 2 2 1 3 3 3 0 Interleukin 31 ATP-synt_G PF04718.10 CAR24873.1 - 1.8 9.2 5.1 0.74 10.4 0.4 2.6 2 2 1 3 3 3 0 Mitochondrial ATP synthase g subunit Aldedh PF00171.17 CAR24874.1 - 2.1e-127 425.2 0.0 2.5e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family V-ATPase_G PF03179.10 CAR24875.1 - 2.6e-31 108.0 10.1 2.9e-31 107.8 7.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3164 PF11363.3 CAR24875.1 - 0.0036 16.7 3.3 0.0043 16.4 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3164) DUF3552 PF12072.3 CAR24875.1 - 0.011 14.9 7.8 0.011 14.9 5.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) RNA_pol_Rpc4 PF05132.9 CAR24875.1 - 0.017 15.1 4.6 0.021 14.8 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2362 PF10154.4 CAR24875.1 - 0.017 13.7 2.0 0.019 13.6 1.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) ATP-synt_B PF00430.13 CAR24875.1 - 0.023 14.4 10.4 0.023 14.4 7.2 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) GA PF01468.12 CAR24875.1 - 0.57 10.3 9.3 0.082 13.0 3.5 1.9 2 1 0 2 2 2 0 GA module DUF1666 PF07891.7 CAR24875.1 - 0.64 9.3 4.3 0.63 9.4 2.6 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1666) RusA PF05866.6 CAR24875.1 - 1.9 8.8 4.9 3.2 8.1 3.4 1.4 1 1 0 1 1 1 0 Endodeoxyribonuclease RusA vATP-synt_E PF01991.13 CAR24875.1 - 9.8 5.3 14.8 4.1 6.6 7.3 1.9 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit zf-HIT PF04438.11 CAR24876.1 - 9e-08 31.6 11.5 1.5e-07 30.8 8.0 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF1610 PF07754.6 CAR24876.1 - 0.13 12.3 6.4 0.33 11.1 4.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) PolC_DP2 PF03833.8 CAR24876.1 - 0.18 9.4 3.7 0.24 9.0 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 CDC45 PF02724.9 CAR24876.1 - 7.1 4.5 9.8 13 3.6 6.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Cyt-b5 PF00173.23 CAR24877.1 - 3.2e-14 52.4 0.0 7.2e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 CAR24877.1 - 1.3e-08 34.6 4.0 2.3e-08 33.7 2.3 1.8 2 0 0 2 2 2 1 Fatty acid desaturase SRP54 PF00448.17 CAR24878.1 - 1.2e-46 158.6 0.1 2.2e-44 151.2 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRX PF09201.5 CAR24878.1 - 3.1e-44 150.2 0.6 6.5e-44 149.1 0.1 1.9 2 0 0 2 2 2 1 SRX SRP54_N PF02881.14 CAR24878.1 - 2.7e-07 30.5 0.1 1.1e-06 28.6 0.1 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRP-alpha_N PF04086.8 CAR24878.1 - 5.7e-07 29.1 0.4 1.2e-06 28.1 0.3 1.5 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 CAR24878.1 - 1.2e-06 28.0 0.0 3.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CAR24878.1 - 1.4e-06 27.2 0.3 5.1e-06 25.4 0.0 2.0 2 1 0 2 2 2 1 ArgK protein ArsA_ATPase PF02374.10 CAR24878.1 - 0.00067 18.7 0.0 0.087 11.8 0.0 2.4 2 0 0 2 2 2 1 Anion-transporting ATPase MobB PF03205.9 CAR24878.1 - 0.0014 18.3 0.0 0.004 16.8 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CAR24878.1 - 0.0059 16.7 0.0 0.06 13.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CAR24878.1 - 0.0064 16.5 0.1 0.019 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Fer4_NifH PF00142.13 CAR24878.1 - 0.046 12.8 0.0 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_10 PF12846.2 CAR24878.1 - 0.052 12.9 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 CAR24878.1 - 0.89 9.3 4.5 1.1 9.0 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function DUF87 DEAD PF00270.24 CAR24879.1 - 4.5e-23 81.5 0.0 1.6e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.5 CAR24879.1 - 3.2e-14 53.2 0.1 8.8e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 CAR24879.1 - 1.3e-11 44.2 0.0 6e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CAR24879.1 - 0.00024 21.1 0.8 0.00066 19.6 0.6 1.8 1 0 0 1 1 1 1 DNA replication factor CDT1 like CTD_bind PF04818.8 CAR24880.1 - 1.3e-22 79.7 0.1 5.8e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF2051 PF09738.4 CAR24880.1 - 0.0059 15.9 0.4 0.011 15.0 0.3 1.5 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) CTK3 PF12243.3 CAR24880.1 - 0.027 14.0 1.5 0.039 13.5 0.2 1.9 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 DUF3496 PF12001.3 CAR24880.1 - 3 8.1 8.1 0.24 11.6 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) Med20 PF08612.6 CAR24881.1 - 3.3e-46 157.2 0.0 3.7e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex HGTP_anticodon2 PF12745.2 CAR24882.1 - 1.9e-98 328.9 1.9 1.9e-98 328.9 1.3 2.5 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 CAR24882.1 - 3.2e-69 232.9 6.2 6.7e-44 149.9 0.0 4.3 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24882.1 - 2.3e-40 138.3 0.0 1.2e-22 80.2 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 CAR24882.1 - 2.1e-17 63.0 2.4 9.4e-17 60.9 1.7 2.2 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 CAR24882.1 - 8.7e-12 44.7 0.0 2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 CAR24882.1 - 0.009 15.0 0.0 0.23 10.3 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CAR24882.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAP2 PF01569.16 CAR24883.1 - 1.6e-21 76.3 0.5 1.6e-21 76.3 0.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF2177 PF09945.4 CAR24883.1 - 0.015 15.2 5.6 2.6 8.0 0.8 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) DsbB PF02600.11 CAR24883.1 - 0.05 13.3 0.9 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB DUF836 PF05768.9 CAR24884.1 - 1e-18 67.3 0.1 1.2e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 CAR24884.1 - 0.0014 18.5 0.1 0.0032 17.4 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 CAR24884.1 - 0.013 15.7 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.16 CAR24884.1 - 0.069 12.8 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 CAR24884.1 - 0.11 12.0 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin Inositol_P PF00459.20 CAR24885.1 - 1e-71 241.3 0.0 1.3e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MAGE PF01454.14 CAR24886.1 - 6.8e-29 100.6 0.0 8.2e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 MAGE family KAR9 PF08580.5 CAR24886.1 - 0.031 12.5 0.3 0.045 12.0 0.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 FAD_binding_1 PF00667.15 CAR24887.1 - 1.8e-67 226.9 0.0 3.4e-67 226.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CAR24887.1 - 2.5e-32 111.8 0.5 4.5e-32 111.0 0.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CAR24887.1 - 1.7e-21 76.8 0.0 1e-20 74.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.5 CAR24887.1 - 0.00019 20.2 0.0 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) Flavodoxin_5 PF12724.2 CAR24887.1 - 0.025 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain DUF155 PF02582.9 CAR24888.1 - 3.6e-42 144.2 0.2 5.5e-42 143.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RCC1_2 PF13540.1 CAR24888.1 - 0.19 11.4 1.9 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat RNase_PH PF01138.16 CAR24889.1 - 8.8e-18 64.8 0.0 1.6e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CAR24889.1 - 3.1e-13 49.4 0.2 8.1e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_H2-Ydr279 PF09468.5 CAR24890.1 - 1e-48 166.1 4.9 1.2e-48 165.8 3.4 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF2149 PF09919.4 CAR24890.1 - 0.0039 17.2 0.2 0.0085 16.1 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2149) ORC4_C PF14629.1 CAR24890.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF3985 PF13153.1 CAR24891.1 - 0.23 11.2 0.8 0.51 10.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3985) Inositol_P PF00459.20 CAR24892.1 - 3.3e-66 223.3 0.0 3.7e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family T4_Gp59_C PF08994.5 CAR24892.1 - 0.065 13.4 0.0 0.87 9.7 0.1 2.2 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Peptidase_M1 PF01433.15 CAR24893.1 - 1.7e-146 488.3 2.5 2.3e-146 487.8 1.7 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CAR24893.1 - 1e-92 310.8 1.4 4e-92 308.9 0.3 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CAR24893.1 - 2.2e-20 72.9 0.3 5.6e-20 71.6 0.2 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily HEAT_2 PF13646.1 CAR24893.1 - 0.02 15.1 0.0 5.6 7.3 0.0 2.8 2 1 0 2 2 2 0 HEAT repeats MFS_1 PF07690.11 CAR24894.1 - 2.2e-36 125.3 38.2 2.2e-36 125.3 26.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR24894.1 - 4.7e-11 41.9 30.5 6.9e-11 41.3 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter FSH1 PF03959.8 CAR24895.1 - 4.7e-62 209.1 0.0 5.3e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CAR24895.1 - 1.6e-06 27.9 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR24895.1 - 1.8e-06 28.0 0.0 2.6e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CAR24895.1 - 0.00018 21.0 0.2 0.0063 15.9 0.1 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CAR24895.1 - 0.028 14.1 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Nramp PF01566.13 CAR24896.1 - 2.6e-92 309.4 15.5 3.4e-92 309.0 10.7 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Calcipressin PF04847.7 CAR24897.1 - 2.3e-17 63.1 0.9 2.7e-17 62.9 0.6 1.3 1 1 0 1 1 1 1 Calcipressin Med25_SD1 PF11235.3 CAR24897.1 - 0.012 15.9 1.5 0.017 15.4 1.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 COX5A PF02284.11 CAR24898.1 - 2e-49 166.0 2.3 2.8e-49 165.5 1.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF488 PF04343.8 CAR24898.1 - 0.0029 17.9 0.9 0.023 15.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF488 Elf1 PF05129.8 CAR24899.1 - 6.9e-31 105.7 0.9 9.9e-31 105.2 0.6 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 CAR24899.1 - 0.35 10.8 0.3 0.35 10.8 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger CDC45 PF02724.9 CAR24899.1 - 0.97 7.3 7.7 1.1 7.2 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L44 PF00935.14 CAR24899.1 - 1.9 8.5 8.1 0.83 9.7 1.0 2.5 2 1 1 3 3 3 0 Ribosomal protein L44 Ribosomal_L1 PF00687.16 CAR24900.1 - 3.8e-43 147.3 4.7 6.7e-43 146.5 3.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GCR1_C PF12550.3 CAR24901.1 - 2e-17 62.8 0.9 3.7e-17 61.9 0.6 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes UBN2 PF14223.1 CAR24901.1 - 0.013 15.2 1.0 5.3 6.8 0.0 2.8 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type MatE PF01554.13 CAR24902.1 - 1.9e-61 206.4 26.6 3.9e-32 111.1 6.0 2.3 2 0 0 2 2 2 2 MatE DUF2484 PF10658.4 CAR24902.1 - 4.2 7.5 15.8 0.24 11.5 1.4 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2484) PIF1 PF05970.9 CAR24903.1 - 6.3e-59 199.7 2.7 3.6e-47 161.0 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CAR24903.1 - 2.2e-17 63.2 0.0 8.9e-17 61.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR24903.1 - 2.2e-05 24.6 0.0 6.6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CAR24903.1 - 3.5e-05 21.7 0.2 0.00074 17.3 0.0 2.4 3 0 0 3 3 3 1 Helicase TrwB_AAD_bind PF10412.4 CAR24903.1 - 0.00082 18.0 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 CAR24903.1 - 0.0021 18.0 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 CAR24903.1 - 0.0042 16.1 0.6 0.016 14.1 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CAR24903.1 - 0.0058 15.8 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein UvrD_C_2 PF13538.1 CAR24903.1 - 0.0073 16.4 0.0 0.03 14.4 0.0 2.1 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 CAR24903.1 - 0.0074 16.4 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CAR24903.1 - 0.0083 15.8 0.5 0.02 14.6 0.4 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 CAR24903.1 - 0.0092 14.9 1.2 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_11 PF13086.1 CAR24903.1 - 0.02 14.4 0.7 1.5 8.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain MobB PF03205.9 CAR24903.1 - 0.047 13.4 0.2 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Helicase_RecD PF05127.9 CAR24903.1 - 0.061 12.9 0.4 0.19 11.3 0.3 1.8 1 1 0 1 1 1 0 Helicase ABC_tran PF00005.22 CAR24903.1 - 0.081 13.2 0.1 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Pkinase PF00069.20 CAR24904.1 - 8.3e-70 234.8 0.3 1.9e-69 233.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR24904.1 - 1.7e-30 105.9 0.0 3.4e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR24904.1 - 0.0052 16.5 0.8 0.06 13.0 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family PhzC-PhzF PF02567.11 CAR24905.1 - 3.3e-63 213.5 0.0 3.7e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.14 CAR24905.1 - 0.014 15.3 0.0 0.089 12.7 0.0 2.3 3 0 0 3 3 3 0 Diaminopimelate epimerase UPF0020 PF01170.13 CAR24905.1 - 0.038 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DPPIV_N PF00930.16 CAR24906.1 - 2.5e-107 358.5 2.7 3.2e-107 358.1 1.9 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CAR24906.1 - 9.1e-53 178.6 1.5 1.4e-52 178.0 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CAR24906.1 - 1.5e-08 34.4 0.0 3.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR24906.1 - 0.00062 19.7 0.0 0.0077 16.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CAR24906.1 - 0.014 14.8 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PC_rep PF01851.17 CAR24907.1 - 2.2e-26 90.5 9.6 2.8e-06 27.2 0.1 8.9 8 0 0 8 8 8 6 Proteasome/cyclosome repeat ATP-synt_C PF00137.16 CAR24908.1 - 2.8e-29 100.7 26.0 5.1e-18 64.7 5.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Sensor_TM1 PF13755.1 CAR24908.1 - 0.13 11.7 1.7 2.4 7.7 0.2 2.4 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain GHMP_kinases_N PF00288.21 CAR24909.1 - 7.2e-13 48.4 0.0 1.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CAR24909.1 - 0.0022 18.1 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16 PF00675.15 CAR24910.1 - 2.9e-46 156.9 0.1 7.7e-44 149.0 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CAR24910.1 - 3.4e-45 153.9 0.0 1.4e-44 151.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain SnoaL_3 PF13474.1 CAR24910.1 - 0.14 12.2 0.1 0.97 9.4 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain Myosin_head PF00063.16 CAR24911.1 - 1.8e-242 806.3 12.2 1.8e-242 806.3 8.4 3.6 4 1 0 4 4 4 1 Myosin head (motor domain) F-box-like PF12937.2 CAR24912.1 - 0.0023 17.6 0.2 0.012 15.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like PRANC PF09372.5 CAR24912.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Ras PF00071.17 CAR24913.1 - 1.1e-24 86.6 0.1 2.3e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CAR24913.1 - 2.8e-09 37.5 0.0 8.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 CAR24913.1 - 0.001 18.5 0.1 0.0021 17.4 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CAR24913.1 - 0.02 14.8 0.1 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 CAR24913.1 - 0.08 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 CAR24913.1 - 0.083 12.3 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 CAR24913.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_S27e PF01667.12 CAR24915.1 - 7.1e-30 102.3 2.5 9.5e-30 101.9 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CAR24915.1 - 0.00012 21.8 0.5 0.00014 21.6 0.4 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CAR24915.1 - 0.012 14.9 3.3 0.018 14.3 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Rsm22 PF09243.5 CAR24916.1 - 1.4e-26 93.1 0.0 5.5e-09 35.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 CAR24916.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain SRPRB PF09439.5 CAR24917.1 - 8.1e-64 214.1 0.0 1e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CAR24917.1 - 8e-08 31.7 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAR24917.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CAR24917.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein DUF3414 PF11894.3 CAR24918.1 - 0 1372.4 46.0 0 1372.2 31.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Nsp1_C PF05064.8 CAR24919.1 - 1.5e-36 124.6 1.4 1.5e-36 124.6 1.0 2.1 1 1 1 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CAR24919.1 - 0.0048 17.1 23.5 0.0048 17.1 16.3 8.3 1 1 7 8 8 8 3 Nucleoporin FG repeat region Muted PF14942.1 CAR24919.1 - 0.0069 16.2 2.0 0.012 15.4 1.4 1.4 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein SHIPPO-rpt PF07004.7 CAR24919.1 - 2 9.4 51.9 27 5.9 0.2 14.3 7 4 1 8 8 8 0 Sperm-tail PG-rich repeat LRR_4 PF12799.2 CAR24920.1 - 0.015 14.8 4.6 6.5 6.5 1.5 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Rep_fac_C PF08542.6 CAR24920.1 - 0.073 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Replication factor C C-terminal domain RabGAP-TBC PF00566.13 CAR24921.1 - 1.5e-23 83.3 0.4 2.3e-23 82.8 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain His_Phos_1 PF00300.17 CAR24922.1 - 1.3e-41 142.3 0.0 2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Carb_kinase PF01256.12 CAR24923.1 - 3.3e-60 203.3 0.0 8.9e-60 201.9 0.0 1.6 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CAR24923.1 - 7.1e-05 22.1 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase NAD_binding_1 PF00175.16 CAR24924.1 - 2.1e-25 89.3 0.0 3.4e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CAR24924.1 - 3.8e-24 84.6 0.0 7.2e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CAR24924.1 - 3.6e-06 26.9 0.0 0.00042 20.2 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Metallophos PF00149.23 CAR24925.1 - 9.8e-08 31.6 0.4 1.5e-06 27.7 0.3 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DBR1 PF05011.8 CAR24925.1 - 1.5e-07 31.4 0.0 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain FAD_binding_2 PF00890.19 CAR24926.1 - 1.9e-123 412.4 5.1 2.4e-123 412.0 3.5 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CAR24926.1 - 1.9e-44 150.6 0.3 2.9e-44 150.0 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.17 CAR24926.1 - 1.3e-06 27.5 0.4 0.0015 17.4 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 CAR24926.1 - 3.7e-06 26.0 3.9 1.4e-05 24.1 2.6 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CAR24926.1 - 7.8e-06 25.9 4.7 0.002 18.0 3.2 3.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CAR24926.1 - 1.1e-05 24.6 0.4 0.0076 15.3 0.0 3.1 4 0 0 4 4 4 2 Thi4 family FAD_binding_3 PF01494.14 CAR24926.1 - 0.0012 18.0 0.6 0.0048 15.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CAR24926.1 - 0.052 12.0 0.4 0.2 10.0 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Aa_trans PF01490.13 CAR24927.1 - 5.4e-95 318.2 30.8 6.4e-95 318.0 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CAR24927.1 - 0.00028 19.5 27.0 0.00028 19.5 18.7 2.0 1 1 1 2 2 2 1 Amino acid permease AAA PF00004.24 CAR24928.1 - 4.8e-40 136.8 0.0 1.2e-39 135.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR24928.1 - 2.4e-06 27.7 0.0 0.00091 19.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CAR24928.1 - 1.7e-05 24.5 0.0 8.9e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR24928.1 - 0.00013 21.9 0.0 0.0013 18.7 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CAR24928.1 - 0.00035 20.5 0.0 0.00082 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CAR24928.1 - 0.0012 19.6 0.7 0.003 18.3 0.0 2.1 2 2 0 2 2 2 1 AAA domain DUF815 PF05673.8 CAR24928.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CAR24928.1 - 0.0039 16.2 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CAR24928.1 - 0.0044 16.7 0.1 0.0086 15.8 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CAR24928.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAR24928.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CAR24928.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CAR24928.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CAR24928.1 - 0.019 15.3 0.0 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CAR24928.1 - 0.029 14.5 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 CAR24928.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CAR24928.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CAR24928.1 - 0.039 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 CAR24928.1 - 0.043 12.5 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CAR24928.1 - 0.044 12.9 0.0 0.094 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CAR24928.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_Rbc25 PF08292.7 CAR24929.1 - 2.2e-46 157.0 0.5 3.2e-46 156.4 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CAR24929.1 - 4.3e-20 71.6 0.0 6.5e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CAR24929.1 - 0.035 14.1 0.4 0.092 12.8 0.0 2.0 2 1 0 2 2 2 0 S1 RNA binding domain LTV PF04180.9 CAR24930.1 - 6.8e-108 361.8 32.2 8e-108 361.6 22.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF4559 PF15112.1 CAR24930.1 - 5 6.2 12.1 0.13 11.4 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) DUF3294 PF07957.6 CAR24931.1 - 1.3e-82 276.4 6.4 1.5e-82 276.3 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) PUF PF00806.14 CAR24932.1 - 1.1e-29 100.1 3.8 0.00056 19.2 0.0 9.2 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat MA3 PF02847.12 CAR24932.1 - 0.043 13.5 0.6 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 MA3 domain Cpn60_TCP1 PF00118.19 CAR24933.1 - 1e-138 462.9 6.0 1.2e-138 462.7 4.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps53_N PF04100.7 CAR24934.1 - 4.5e-83 279.1 3.4 4.5e-83 279.1 2.4 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal Scytalone_dh PF02982.9 CAR24934.1 - 0.011 15.3 0.0 0.064 12.8 0.0 2.1 2 0 0 2 2 2 0 Scytalone dehydratase HORMA PF02301.13 CAR24935.1 - 5.7e-46 156.6 0.9 6.5e-46 156.4 0.6 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 CAR24935.1 - 0.0042 16.5 0.1 0.0056 16.1 0.0 1.5 1 1 0 1 1 1 1 Autophagy-related protein 13 Med30 PF11315.3 CAR24935.1 - 0.017 15.2 0.2 0.029 14.5 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 RBD-FIP PF09457.5 CAR24935.1 - 0.99 9.2 6.0 0.93 9.3 0.4 2.4 2 0 0 2 2 2 0 FIP domain Cyclin_N PF00134.18 CAR24936.1 - 8.7e-17 60.8 6.3 6.8e-15 54.7 2.4 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain DEAD PF00270.24 CAR24937.1 - 1.8e-44 151.1 2.3 8.1e-44 149.0 0.0 2.9 4 0 0 4 4 4 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CAR24937.1 - 2.1e-24 84.8 0.1 4.6e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CAR24937.1 - 1.4e-21 76.1 0.0 3.1e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CAR24937.1 - 0.00045 20.2 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain FAD_binding_9 PF08021.6 CAR24937.1 - 0.017 15.1 0.2 6.7 6.7 0.0 3.3 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain FHA PF00498.21 CAR24938.1 - 5.2e-14 52.1 0.0 1.2e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 FHA domain HSP70 PF00012.15 CAR24939.1 - 1.2e-266 885.4 13.7 1.4e-266 885.2 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR24939.1 - 3.4e-17 62.0 1.0 5.4e-16 58.0 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CAR24939.1 - 0.0078 15.3 6.8 0.026 13.6 0.1 2.9 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase DDR PF08841.5 CAR24939.1 - 0.012 14.4 2.6 0.045 12.5 0.6 2.5 1 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain CENP-I PF07778.6 CAR24939.1 - 2 6.5 5.6 3 5.9 0.1 2.1 2 0 0 2 2 2 0 Mis6 FtsA PF14450.1 CAR24939.1 - 5.6 6.8 11.5 0.42 10.4 0.1 3.6 4 1 0 4 4 4 0 Cell division protein FtsA dCMP_cyt_deam_1 PF00383.17 CAR24940.1 - 2.4e-23 81.6 0.1 3.5e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 CAR24940.1 - 8.2e-05 22.3 0.0 0.00018 21.1 0.0 1.5 2 0 0 2 2 2 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 CAR24940.1 - 0.0031 17.3 0.1 0.01 15.6 0.1 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase MafB19-deam PF14437.1 CAR24940.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase PX PF00787.19 CAR24941.1 - 2.3e-24 85.3 0.6 8.3e-24 83.5 0.4 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CAR24941.1 - 3.9e-05 23.0 17.4 0.00084 18.6 3.7 2.5 2 1 0 2 2 2 2 Vps5 C terminal like RmuC PF02646.11 CAR24941.1 - 0.013 14.3 1.9 0.013 14.3 1.3 2.0 2 0 0 2 2 2 0 RmuC family Reo_sigmaC PF04582.7 CAR24941.1 - 0.018 14.2 5.6 0.021 14.0 0.9 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 CAR24941.1 - 0.057 13.6 5.4 4.5 7.5 0.0 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 CAR24941.1 - 0.064 13.0 6.5 0.11 12.2 0.4 2.8 2 1 0 2 2 2 0 Laminin Domain II ACR_tran PF00873.14 CAR24941.1 - 0.11 9.8 0.2 0.16 9.3 0.2 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family RNase_T PF00929.19 CAR24941.1 - 0.25 11.6 3.5 0.38 11.0 0.4 2.7 3 1 1 4 4 4 0 Exonuclease Prefoldin_2 PF01920.15 CAR24941.1 - 0.26 11.0 6.5 7.1 6.4 0.3 3.0 2 0 0 2 2 2 0 Prefoldin subunit BAR PF03114.13 CAR24941.1 - 0.55 9.7 13.1 0.24 10.8 2.3 2.7 1 1 1 2 2 2 0 BAR domain bZIP_1 PF00170.16 CAR24941.1 - 0.56 10.2 6.8 1.8 8.6 0.0 3.2 3 0 0 3 3 2 0 bZIP transcription factor Atg14 PF10186.4 CAR24941.1 - 0.58 9.0 10.0 0.26 10.1 0.9 2.3 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1877 PF08974.5 CAR24941.1 - 0.68 9.5 7.7 2.1 7.9 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1877) DUF948 PF06103.6 CAR24941.1 - 0.71 9.7 3.0 1.9 8.4 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 CAR24941.1 - 1.4 8.7 7.3 7.5 6.3 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CAR24941.1 - 1.8 8.4 10.5 3.7 7.5 0.1 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.1 CAR24941.1 - 2.4 7.4 14.8 2.1 7.6 6.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.5 CAR24941.1 - 3.9 7.5 10.6 13 5.8 0.4 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 CAR24941.1 - 4.4 7.6 12.1 0.75 10.1 0.3 4.4 4 1 0 4 4 4 0 Snapin/Pallidin DUF641 PF04859.7 CAR24941.1 - 5 6.9 8.8 0.33 10.7 0.1 3.0 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Gp-FAR-1 PF05823.7 CAR24941.1 - 6.5 6.7 13.1 0.17 11.8 3.1 2.5 2 2 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Nup54 PF13874.1 CAR24941.1 - 7.7 6.1 6.7 1.1 8.9 0.4 2.5 3 0 0 3 3 2 0 Nucleoporin complex subunit 54 SPRY PF00622.23 CAR24942.1 - 0.00031 20.8 0.1 0.018 15.1 0.0 2.3 2 0 0 2 2 2 2 SPRY domain Fungal_trans PF04082.13 CAR24943.1 - 1.1e-45 155.5 0.8 5.6e-45 153.2 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR24943.1 - 1.5e-10 40.8 10.0 2.9e-10 39.8 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4568 PF15132.1 CAR24943.1 - 0.025 13.8 0.4 0.07 12.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4568) Mito_carr PF00153.22 CAR24944.1 - 6.5e-58 192.4 2.2 7.8e-20 70.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_15 PF01793.11 CAR24945.1 - 1.8e-141 470.8 6.0 2.2e-141 470.5 4.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Nup_retrotrp_bd PF10599.4 CAR24946.1 - 0.0027 18.3 11.6 0.0027 18.3 8.0 8.1 1 1 4 6 6 6 1 Retro-transposon transporting motif Mannosyl_trans3 PF11051.3 CAR24947.1 - 1.5e-65 221.2 0.0 2e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative SP_C-Propep PF08999.5 CAR24948.1 - 0.16 11.4 1.4 0.23 10.9 1.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide TadE PF07811.7 CAR24948.1 - 1.4 8.8 4.8 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 TadE-like protein Ribosomal_S7e PF01251.13 CAR24949.1 - 7.1e-82 273.5 2.3 8.5e-82 273.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Rib_5-P_isom_A PF06026.9 CAR24950.1 - 1.7e-54 183.7 0.0 2.2e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Arf PF00025.16 CAR24951.1 - 2.6e-69 231.9 0.3 3e-69 231.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAR24951.1 - 9.5e-15 54.2 0.0 1.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR24951.1 - 8.1e-13 48.0 0.0 9.4e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAR24951.1 - 8.8e-13 47.6 0.8 1.8e-08 33.4 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAR24951.1 - 5.5e-11 42.0 0.1 6.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR24951.1 - 1.9e-08 34.8 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR24951.1 - 4.4e-06 26.6 0.0 8e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CAR24951.1 - 0.15 11.1 0.9 0.3 10.1 0.1 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AMP-binding PF00501.23 CAR24952.1 - 4.3e-37 127.5 0.0 4.7e-11 41.7 0.0 5.1 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.6 CAR24952.1 - 2.7e-12 47.2 0.2 7.8e-12 45.7 0.1 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain Mem_trans PF03547.13 CAR24953.1 - 6.7e-85 284.7 0.7 8.2e-85 284.4 0.5 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF2183 PF09949.4 CAR24954.1 - 7.3e-31 106.0 0.0 2.7e-30 104.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) zf-CCCH PF00642.19 CAR24955.1 - 2.6e-05 23.7 0.3 2.6e-05 23.7 0.2 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PP2C PF00481.16 CAR24956.1 - 8.5e-43 146.5 0.0 2.5e-42 145.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Ras PF00071.17 CAR24957.1 - 2.3e-59 199.4 0.0 2.7e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR24957.1 - 5.7e-20 72.0 0.0 8.8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR24957.1 - 1.1e-17 63.8 0.0 1.2e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR24957.1 - 1.2e-07 31.1 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR24957.1 - 7.4e-07 28.7 0.0 1.3e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR24957.1 - 6.1e-05 22.9 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ion_trans PF00520.26 CAR24958.1 - 0.00024 20.4 16.6 0.00024 20.4 11.5 1.9 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 CAR24958.1 - 1.2 7.4 16.4 0.2 10.0 7.1 2.5 2 1 0 2 2 2 0 Polycystin cation channel NST1 PF13945.1 CAR24959.1 - 3.5e-12 46.7 13.1 3.5e-12 46.7 9.1 6.1 4 2 1 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 CAR24960.1 - 1.2e-50 171.0 0.0 1.4e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR24960.1 - 9.2e-15 55.1 0.0 1.3e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR24960.1 - 1.8e-08 33.8 0.0 2.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 CAR24960.1 - 0.0022 17.5 0.0 1.6 8.2 0.0 2.2 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 CAR24960.1 - 0.016 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_21 PF13304.1 CAR24960.1 - 0.048 13.6 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 CAR24960.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DNA_topoisoIV PF00521.15 CAR24961.1 - 2.5e-122 408.7 2.2 4.1e-122 408.1 0.0 2.3 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CAR24961.1 - 7.2e-36 123.0 7.1 1.9e-35 121.6 4.9 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CAR24961.1 - 3e-12 46.3 0.1 1.5e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 CAR24961.1 - 1.7e-10 40.6 0.3 8.3e-10 38.3 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase C2 PF00168.25 CAR24962.1 - 4.9e-54 180.1 1.8 3.8e-20 71.5 0.1 4.5 4 0 0 4 4 4 4 C2 domain PP_M1 PF03012.9 CAR24962.1 - 0.29 10.4 5.0 0.58 9.4 3.5 1.4 1 0 0 1 1 1 0 Phosphoprotein DUF2390 PF09523.5 CAR24963.1 - 0.001 19.2 1.3 0.0013 18.9 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2390) Tmemb_cc2 PF10267.4 CAR24963.1 - 0.0085 14.7 1.9 0.0093 14.5 1.3 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Snapin_Pallidin PF14712.1 CAR24963.1 - 0.018 15.3 3.9 0.063 13.5 2.8 1.7 1 1 0 1 1 1 0 Snapin/Pallidin Gp-FAR-1 PF05823.7 CAR24963.1 - 0.067 13.1 0.7 0.078 12.9 0.5 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) IncA PF04156.9 CAR24963.1 - 0.075 12.6 3.5 0.098 12.2 2.4 1.2 1 0 0 1 1 1 0 IncA protein Syntaxin_2 PF14523.1 CAR24963.1 - 0.24 11.4 1.6 0.43 10.6 1.1 1.4 1 1 0 1 1 1 0 Syntaxin-like protein Syntaxin PF00804.20 CAR24963.1 - 0.35 11.0 1.7 0.94 9.6 1.2 1.8 1 1 0 1 1 1 0 Syntaxin TMF_TATA_bd PF12325.3 CAR24963.1 - 0.56 9.9 7.7 2.8 7.7 5.5 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding OST3_OST6 PF04756.8 CAR24964.1 - 7.1e-22 77.6 3.9 1.2e-21 76.9 2.7 1.4 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 CAR24964.1 - 0.0034 17.0 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF1129 PF06570.6 CAR24964.1 - 0.014 14.7 0.3 0.014 14.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) MKT1_C PF12246.3 CAR24965.1 - 9.3e-65 217.9 0.7 1.5e-64 217.2 0.5 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CAR24965.1 - 2.9e-33 114.0 0.1 8.3e-33 112.5 0.0 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 CAR24965.1 - 1.5e-20 73.2 0.0 4.4e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CAR24965.1 - 1.2e-07 31.6 0.0 2.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Cpn60_TCP1 PF00118.19 CAR24966.1 - 5.9e-138 460.5 9.6 6.9e-138 460.2 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 CAR24966.1 - 0.0097 15.3 0.1 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 TNP1/EN/SPM transposase EF-hand_4 PF12763.2 CAR24967.1 - 5.3e-48 161.0 1.9 2e-47 159.1 1.3 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 CAR24967.1 - 6e-32 110.8 0.2 9.8e-32 110.1 0.1 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 CAR24967.1 - 0.014 14.6 1.4 0.075 12.3 1.3 2.1 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CAR24967.1 - 0.32 10.6 2.8 0.27 10.8 0.7 1.9 2 0 0 2 2 2 0 EF-hand domain pair SKG6 PF08693.5 CAR24968.1 - 2.2e-14 52.4 0.5 5.8e-14 51.1 0.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain He_PIG PF05345.7 CAR24968.1 - 1.2e-12 47.6 1.8 0.0006 19.7 0.0 4.2 4 0 0 4 4 4 3 Putative Ig domain Rifin_STEVOR PF02009.11 CAR24968.1 - 4.8e-05 23.1 0.1 8.2e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 CAR24968.1 - 0.00031 20.4 1.0 0.00084 19.0 0.7 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 CAR24968.1 - 0.00038 20.0 0.4 0.00089 18.7 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 CAR24968.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 4HBT PF03061.17 CAR24969.1 - 9.1e-07 28.9 0.5 0.015 15.3 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Mito_carr PF00153.22 CAR24970.1 - 7.4e-63 208.2 2.4 3.5e-21 74.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CAR24970.1 - 1.5e-16 60.2 0.8 1e-11 44.8 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CAR24970.1 - 3.1e-14 51.1 4.0 0.00051 19.1 0.0 4.3 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 CAR24970.1 - 1.5e-11 43.1 1.8 0.014 15.1 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CAR24970.1 - 3.4e-08 32.9 0.2 0.057 13.0 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 CAR24970.1 - 4.6e-05 23.2 0.0 0.026 14.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CAR24970.1 - 0.00014 21.0 7.9 0.0094 15.2 0.1 3.6 3 0 0 3 3 3 2 EF hand HORMA PF02301.13 CAR24971.1 - 1.8e-21 76.5 0.5 2.5e-21 76.1 0.4 1.1 1 0 0 1 1 1 1 HORMA domain MutL_C PF08676.6 CAR24972.1 - 4.9e-24 84.5 0.0 8.9e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CAR24972.1 - 1.2e-23 82.7 0.2 3.4e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 CAR24972.1 - 1e-10 41.3 0.0 3.1e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CAR24972.1 - 1.3e-08 34.5 0.0 3.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S13 PF00416.17 CAR24973.1 - 4.2e-22 78.6 0.0 5.7e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 EF_assoc_2 PF08356.7 CAR24973.1 - 0.12 12.0 0.1 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 EF hand associated EOS1 PF12326.3 CAR24974.1 - 6e-70 233.6 9.5 1e-69 232.8 6.6 1.4 1 0 0 1 1 1 1 N-glycosylation protein Ubie_methyltran PF01209.13 CAR24975.1 - 2e-97 324.8 0.2 2.3e-97 324.6 0.2 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CAR24975.1 - 2.4e-13 49.9 0.0 4.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR24975.1 - 1.2e-09 38.4 0.0 2.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR24975.1 - 1.9e-09 37.8 0.1 3.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR24975.1 - 3.7e-08 33.6 0.0 6.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR24975.1 - 2.5e-07 30.5 0.0 3.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR24975.1 - 2.8e-05 24.6 0.0 5.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR24975.1 - 0.00094 19.2 0.0 0.0034 17.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 CAR24975.1 - 0.041 13.4 0.0 0.41 10.2 0.0 2.1 1 1 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_28 PF02636.12 CAR24975.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Tropomyosin_1 PF12718.2 CAR24976.1 - 2.6e-50 169.9 44.9 3.1e-50 169.7 31.1 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CAR24976.1 - 1.9e-08 33.6 40.2 4.2e-05 22.7 10.9 2.1 1 1 1 2 2 2 2 Tropomyosin Laminin_II PF06009.7 CAR24976.1 - 3.9e-05 23.4 22.6 0.0028 17.4 7.5 2.1 1 1 1 2 2 2 2 Laminin Domain II ATG16 PF08614.6 CAR24976.1 - 4.9e-05 23.2 35.2 0.00017 21.4 10.7 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 CAR24976.1 - 6.6e-05 22.7 44.3 0.00037 20.3 5.5 2.5 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KLRAQ PF10205.4 CAR24976.1 - 0.00026 20.9 27.5 0.00062 19.7 10.5 2.1 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Filament PF00038.16 CAR24976.1 - 0.00063 19.2 32.2 0.018 14.5 8.3 2.0 1 1 1 2 2 2 2 Intermediate filament protein TMF_DNA_bd PF12329.3 CAR24976.1 - 0.00069 19.3 47.8 0.015 15.0 14.2 3.3 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 CAR24976.1 - 0.00075 17.3 38.6 0.00097 16.9 26.8 1.2 1 0 0 1 1 1 1 Myosin tail GAS PF13851.1 CAR24976.1 - 0.00088 18.5 39.5 0.033 13.3 11.5 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 CAR24976.1 - 0.0011 19.0 29.0 0.68 10.0 7.7 3.8 1 1 3 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 CAR24976.1 - 0.0018 18.1 27.5 0.0018 18.1 19.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) ADIP PF11559.3 CAR24976.1 - 0.0019 18.0 37.2 0.17 11.8 10.5 2.7 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding WXG100 PF06013.7 CAR24976.1 - 0.0024 17.8 16.2 0.44 10.5 0.1 3.9 2 1 1 3 3 3 1 Proteins of 100 residues with WXG AAA_27 PF13514.1 CAR24976.1 - 0.003 15.3 24.4 0.0036 15.0 16.9 1.1 1 0 0 1 1 1 1 AAA domain IFT57 PF10498.4 CAR24976.1 - 0.003 16.3 30.8 0.0078 14.9 16.6 2.1 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 Mod_r PF07200.8 CAR24976.1 - 0.0038 17.1 32.9 0.061 13.2 9.3 2.6 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 CAR24976.1 - 0.005 15.9 42.4 0.014 14.4 21.6 2.0 1 1 1 2 2 2 1 Autophagy protein Apg6 Taxilin PF09728.4 CAR24976.1 - 0.0083 15.2 14.7 0.0083 15.2 10.2 2.9 1 1 0 2 2 2 1 Myosin-like coiled-coil protein DUF4201 PF13870.1 CAR24976.1 - 0.0094 15.4 35.1 0.015 14.7 24.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) MbeD_MobD PF04899.7 CAR24976.1 - 0.012 15.4 13.9 0.028 14.3 2.1 2.9 2 1 1 3 3 3 0 MbeD/MobD like Sec2p PF06428.6 CAR24976.1 - 0.013 15.3 17.2 0.013 15.3 12.0 3.3 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Reo_sigmaC PF04582.7 CAR24976.1 - 0.015 14.5 6.9 0.39 9.8 4.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 CAR24976.1 - 0.024 14.1 11.2 0.024 14.1 7.8 4.2 1 1 3 4 4 4 0 Septum formation initiator DUF3287 PF11690.3 CAR24976.1 - 0.025 14.6 4.2 0.025 14.6 2.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) EzrA PF06160.7 CAR24976.1 - 0.029 12.5 29.8 0.12 10.5 3.0 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TelA PF05816.6 CAR24976.1 - 0.034 12.8 23.2 0.21 10.2 0.1 2.3 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) bZIP_1 PF00170.16 CAR24976.1 - 0.037 13.9 38.1 0.49 10.3 1.3 4.4 2 1 2 4 4 4 0 bZIP transcription factor IFP_35_N PF07334.8 CAR24976.1 - 0.053 13.4 3.6 0.053 13.4 2.5 3.7 2 2 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AAA_13 PF13166.1 CAR24976.1 - 0.054 11.9 31.6 0.18 10.2 21.9 1.7 1 1 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 CAR24976.1 - 0.065 12.9 42.4 0.17 11.6 12.1 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.14 CAR24976.1 - 0.071 12.6 40.7 0.019 14.4 16.0 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Nup54 PF13874.1 CAR24976.1 - 0.075 12.6 21.4 0.1 12.2 11.5 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 CAR24976.1 - 0.08 13.2 32.0 0.13 12.6 9.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HOOK PF05622.7 CAR24976.1 - 0.089 10.5 33.5 0.11 10.3 23.2 1.0 1 0 0 1 1 1 0 HOOK protein FlaC_arch PF05377.6 CAR24976.1 - 0.092 12.6 26.2 1.6 8.6 2.1 4.5 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 CAR24976.1 - 0.12 11.0 35.5 0.14 10.8 10.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.3 CAR24976.1 - 0.13 11.5 28.8 0.059 12.6 9.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 CAR24976.1 - 0.13 12.5 13.9 2.2 8.5 0.1 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CCDC155 PF14662.1 CAR24976.1 - 0.15 11.6 40.0 0.28 10.7 12.7 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 IncA PF04156.9 CAR24976.1 - 0.15 11.5 40.4 14 5.2 27.9 2.1 1 1 0 1 1 1 0 IncA protein GOLGA2L5 PF15070.1 CAR24976.1 - 0.18 10.2 28.3 0.34 9.3 19.2 1.6 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Imm15 PF15590.1 CAR24976.1 - 0.19 10.8 3.7 6.2 5.9 0.2 2.9 2 1 1 3 3 3 0 Immunity protein 15 Laminin_I PF06008.9 CAR24976.1 - 0.27 10.4 28.5 0.14 11.4 5.3 2.2 1 1 1 2 2 2 0 Laminin Domain I Rootletin PF15035.1 CAR24976.1 - 0.34 10.8 35.9 0.22 11.5 19.3 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF904 PF06005.7 CAR24976.1 - 0.44 10.8 47.4 3.4 8.0 2.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Spc24 PF08286.6 CAR24976.1 - 0.45 10.2 39.0 0.66 9.6 1.0 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 Ax_dynein_light PF10211.4 CAR24976.1 - 0.46 10.3 36.6 1.2 8.9 15.1 2.8 1 1 3 4 4 4 0 Axonemal dynein light chain Phage_GP20 PF06810.6 CAR24976.1 - 0.48 9.8 37.1 0.51 9.7 11.1 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 CAR24976.1 - 0.48 10.4 33.9 0.8 9.7 1.2 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3552 PF12072.3 CAR24976.1 - 0.49 9.5 39.3 0.37 9.9 10.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF3584 PF12128.3 CAR24976.1 - 0.5 7.6 31.9 0.63 7.2 22.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cortex-I_coil PF09304.5 CAR24976.1 - 0.51 10.4 33.1 0.14 12.2 8.4 3.0 1 1 2 3 3 3 0 Cortexillin I, coiled coil DivIVA PF05103.8 CAR24976.1 - 0.54 10.3 34.3 3.2 7.8 8.9 3.4 1 1 2 3 3 3 0 DivIVA protein HisKA_3 PF07730.8 CAR24976.1 - 0.63 10.4 8.8 12 6.2 0.3 3.8 1 1 2 3 3 3 0 Histidine kinase DUF342 PF03961.8 CAR24976.1 - 0.7 8.2 33.3 0.27 9.5 10.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Atg14 PF10186.4 CAR24976.1 - 0.8 8.5 30.2 0.49 9.3 9.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 CAR24976.1 - 0.81 9.0 38.3 1.3 8.4 16.3 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mnd1 PF03962.10 CAR24976.1 - 0.83 9.2 36.7 2.8 7.5 14.2 2.2 1 1 1 2 2 2 0 Mnd1 family IZUMO PF15005.1 CAR24976.1 - 0.99 9.4 12.8 2.2 8.3 4.2 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion MCPsignal PF00015.16 CAR24976.1 - 1.1 8.7 10.6 1.5 8.3 5.8 1.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.5 CAR24976.1 - 1.1 9.3 23.1 22 5.1 4.1 2.9 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TFR_dimer PF04253.10 CAR24976.1 - 1.2 8.7 9.7 2.1 7.9 0.9 3.2 1 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain TMF_TATA_bd PF12325.3 CAR24976.1 - 1.3 8.8 37.5 2.3 7.9 1.5 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Lectin_N PF03954.9 CAR24976.1 - 1.3 8.4 15.3 0.66 9.3 5.6 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TBPIP PF07106.8 CAR24976.1 - 1.6 8.2 35.4 12 5.3 2.6 2.8 1 1 1 2 2 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 CAR24976.1 - 1.8 8.3 19.5 1.9 8.3 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.10 CAR24976.1 - 1.8 8.4 33.8 0.083 12.7 2.8 4.8 3 3 1 4 4 4 0 Basic region leucine zipper PilJ PF13675.1 CAR24976.1 - 2.2 8.6 13.2 2.9e+03 -1.5 9.2 2.7 1 1 0 1 1 0 0 Type IV pili methyl-accepting chemotaxis transducer N-term KfrA_N PF11740.3 CAR24976.1 - 2.6 8.5 23.9 1.7 9.0 1.4 3.2 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term FemAB PF02388.11 CAR24976.1 - 2.7 6.5 27.3 0.59 8.7 5.5 2.0 1 1 1 2 2 2 0 FemAB family CDC37_N PF03234.9 CAR24976.1 - 2.7 8.2 29.3 23 5.2 20.3 2.2 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4407 PF14362.1 CAR24976.1 - 3.3 6.5 24.3 53 2.6 16.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF869 PF05911.6 CAR24976.1 - 3.4 5.7 35.7 1.1 7.4 19.4 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF724 PF05266.9 CAR24976.1 - 3.4 7.2 33.5 1.4 8.4 9.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Snapin_Pallidin PF14712.1 CAR24976.1 - 3.5 7.9 24.8 16 5.8 0.4 3.6 1 1 3 4 4 4 0 Snapin/Pallidin DUF2203 PF09969.4 CAR24976.1 - 4.1 7.6 20.0 5.1 7.3 4.7 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1319 PF07028.6 CAR24976.1 - 4.3 7.5 23.7 0.058 13.5 5.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) FTA4 PF13093.1 CAR24976.1 - 4.4 6.6 27.8 6.8 6.0 13.4 2.5 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Jnk-SapK_ap_N PF09744.4 CAR24976.1 - 5 7.0 36.2 0.52 10.2 15.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FliD_C PF07195.7 CAR24976.1 - 5.2 6.2 24.5 2.5 7.3 0.2 3.1 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Prominin PF05478.6 CAR24976.1 - 5.3 4.4 18.8 60 0.9 13.0 2.3 1 1 0 1 1 1 0 Prominin DUF3573 PF12097.3 CAR24976.1 - 5.3 5.5 8.1 6.1 5.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FH2 PF02181.18 CAR24976.1 - 5.7 5.7 24.4 5.5 5.7 5.2 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain Fzo_mitofusin PF04799.8 CAR24976.1 - 6.2 6.1 19.6 3.9 6.8 2.7 2.6 1 1 1 2 2 2 0 fzo-like conserved region Prefoldin PF02996.12 CAR24976.1 - 6.6 6.4 31.0 0.69 9.5 0.8 3.9 1 1 5 6 6 6 0 Prefoldin subunit DUF812 PF05667.6 CAR24976.1 - 7.2 4.9 32.3 10 4.5 22.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4600 PF15372.1 CAR24976.1 - 7.4 6.7 30.5 2.3 8.4 7.8 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) DUF4559 PF15112.1 CAR24976.1 - 8.7 5.4 24.5 4.5 6.3 15.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Syntaxin PF00804.20 CAR24976.1 - 8.9 6.5 27.5 5.7 7.1 12.8 2.8 1 1 2 3 3 3 0 Syntaxin HALZ PF02183.13 CAR24976.1 - 9.1 6.0 33.4 2.1 8.1 3.0 4.9 2 1 2 4 4 4 0 Homeobox associated leucine zipper DnaJ PF00226.26 CAR24977.1 - 1.1e-23 82.7 1.7 1.9e-23 81.9 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR24977.1 - 5.3e-16 58.2 0.0 1.5e-14 53.6 0.0 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAR24977.1 - 3.5e-11 42.9 15.9 7.9e-11 41.8 11.0 1.7 1 0 0 1 1 1 1 DnaJ central domain FYVE PF01363.16 CAR24977.1 - 3.8 7.4 9.8 0.51 10.2 0.2 2.9 2 1 1 3 3 3 0 FYVE zinc finger HypA PF01155.14 CAR24977.1 - 4.1 7.1 9.9 5.3 6.7 0.9 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Peptidase_M1 PF01433.15 CAR24978.1 - 1.1e-75 255.1 0.0 2.5e-75 254.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 CAR24978.1 - 7.1e-69 232.5 0.0 1.1e-68 231.9 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CAR24978.1 - 3.9e-15 56.0 0.0 8.1e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Apolipoprotein PF01442.13 CAR24980.1 - 0.00036 20.1 27.1 0.034 13.6 1.0 4.5 2 2 0 3 3 3 3 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 CAR24980.1 - 0.00037 20.3 13.1 0.025 14.3 0.3 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF1664) DUF2215 PF10225.4 CAR24980.1 - 0.044 13.2 2.3 0.16 11.4 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) DOG1 PF14144.1 CAR24980.1 - 1.7 8.7 6.6 0.71 9.9 0.3 3.2 3 1 0 3 3 3 0 Seed dormancy control DUF2317 PF10079.4 CAR24980.1 - 6.9 5.1 31.1 2 6.9 5.4 3.8 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2317) CotJB PF12652.2 CAR24980.1 - 9.6 6.3 12.6 13 5.9 0.2 3.9 2 1 1 3 3 3 0 CotJB protein DUF1752 PF08550.5 CAR24981.1 - 9.4e-11 41.0 0.4 1.9e-10 40.1 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Brix PF04427.13 CAR24982.1 - 9.5e-49 165.6 0.2 1.2e-48 165.3 0.1 1.1 1 0 0 1 1 1 1 Brix domain Kri1 PF05178.7 CAR24982.1 - 0.0011 19.2 1.0 0.0016 18.6 0.7 1.2 1 0 0 1 1 1 1 KRI1-like family tRNA-synt_2 PF00152.15 CAR24984.1 - 1.5e-72 244.2 0.0 1.8e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CAR24984.1 - 2.9e-07 29.9 0.2 4.7e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CAR24984.1 - 5e-05 23.0 0.0 9.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RNase_HII PF01351.13 CAR24985.1 - 1.3e-58 197.9 0.0 1.7e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Vmethyltransf PF01660.12 CAR24985.1 - 0.13 10.8 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase 2-oxoacid_dh PF00198.18 CAR24986.1 - 2.2e-73 246.3 0.1 2.9e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 CAR24986.1 - 2e-16 59.3 0.0 4.4e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 CAR24986.1 - 6.1e-16 57.8 0.1 1.3e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF3614 PF12267.3 CAR24986.1 - 0.19 11.9 1.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Mito_carr PF00153.22 CAR24987.1 - 6.4e-65 214.9 2.6 3.3e-24 84.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L13 PF00572.13 CAR24988.1 - 3.2e-26 91.8 0.8 4.1e-26 91.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 RD3 PF14473.1 CAR24989.1 - 0.044 13.2 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 RD3 protein Fork_head PF00250.13 CAR24990.1 - 3.5e-37 126.3 1.0 1.2e-36 124.5 0.7 1.9 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CAR24990.1 - 9.2e-11 41.7 0.0 2.4e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain RR_TM4-6 PF06459.7 CAR24990.1 - 4.3 7.1 20.7 8.4 6.2 14.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fungal_trans PF04082.13 CAR24991.1 - 5.6e-35 120.4 0.5 9e-35 119.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR24991.1 - 7.6e-12 44.9 10.8 1.3e-11 44.2 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOR2-PAG1_N PF14222.1 CAR24992.1 - 1e-193 645.0 19.3 1.3e-193 644.6 8.6 2.4 2 0 0 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 CAR24992.1 - 6e-96 321.2 2.0 6e-96 321.2 1.4 2.7 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 CAR24992.1 - 6.5e-22 77.0 9.4 2.3e-10 38.8 0.3 3.9 1 1 1 3 3 3 3 Cell morphogenesis central region MMS19_N PF14500.1 CAR24993.1 - 9.1e-93 310.3 11.4 8.2e-91 303.8 0.4 4.1 4 1 0 4 4 4 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CAR24993.1 - 2.9e-90 302.9 17.7 2.9e-90 302.9 12.3 3.1 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 CAR24993.1 - 2.9e-05 24.2 0.5 0.0053 17.0 0.1 3.8 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 CAR24993.1 - 0.00056 19.7 0.7 1.5 9.0 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CAR24993.1 - 0.0019 18.6 0.7 10 6.7 0.0 4.5 3 1 1 4 4 4 2 HEAT-like repeat DUF2435 PF10363.4 CAR24993.1 - 0.0027 17.5 5.4 0.3 11.0 0.1 4.1 2 1 1 3 3 3 2 Protein of unknown function (DUF2435) Ipi1_N PF12333.3 CAR24993.1 - 0.091 12.7 3.7 4 7.4 0.0 4.4 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation CtsR PF05848.6 CAR24994.1 - 0.058 13.3 3.1 0.083 12.8 1.8 1.5 1 1 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) PLRV_ORF5 PF01690.12 CAR24994.1 - 0.74 8.8 9.8 0.88 8.6 6.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SNF2_N PF00176.18 CAR24995.1 - 6.5e-86 287.8 0.3 1.2e-85 286.8 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR24995.1 - 5e-19 67.9 0.3 2.4e-16 59.3 0.0 4.1 5 0 0 5 5 5 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 CAR24995.1 - 6.4e-18 64.4 0.0 1.6e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 CAR24995.1 - 2e-14 53.5 0.5 2e-14 53.5 0.3 4.3 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 CAR24995.1 - 0.0013 18.4 4.1 0.0013 18.4 2.9 2.5 2 0 0 2 2 2 1 HSA Ribosomal_L6 PF00347.18 CAR24996.1 - 5.8e-30 103.6 10.3 1.7e-15 57.2 2.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 CAR24996.1 - 0.0047 16.1 0.9 0.016 14.4 0.0 2.2 3 0 0 3 3 3 1 Transcriptional Coactivator p15 (PC4) DUF2067 PF09840.4 CAR24996.1 - 0.076 12.5 0.4 0.14 11.6 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Transket_pyr PF02779.19 CAR24998.1 - 7.3e-65 217.7 0.0 1.3e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CAR24998.1 - 7.2e-54 182.5 0.0 9.8e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component adh_short PF00106.20 CAR24999.1 - 4.2e-28 98.3 0.0 6.4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR24999.1 - 2.5e-15 56.9 0.0 3.3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR24999.1 - 3.7e-07 29.9 0.0 6.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CAR24999.1 - 7.1e-07 29.4 0.0 2e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 CAR24999.1 - 3.5e-05 23.0 0.0 0.0007 18.8 0.0 2.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 CAR24999.1 - 0.00018 21.0 0.0 0.00052 19.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CAR24999.1 - 0.00046 19.1 0.0 0.00067 18.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CAR24999.1 - 0.044 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SUN PF03856.8 CAR25000.1 - 3.6e-105 350.7 15.9 3.6e-105 350.7 11.0 1.8 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) DUF566 PF04484.7 CAR25000.1 - 7.9 5.8 32.3 13 5.1 22.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) MFS_1 PF07690.11 CAR25001.1 - 4.4e-42 144.0 24.0 2.5e-35 121.8 10.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR25001.1 - 1.1e-09 37.3 27.9 2.9e-09 36.0 8.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CAR25002.1 - 2.6e-42 144.8 21.7 2.6e-42 144.8 15.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR25002.1 - 5e-12 45.1 13.3 5e-12 45.1 9.2 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter DnaJ PF00226.26 CAR25003.1 - 3.6e-24 84.2 1.2 6.4e-24 83.4 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR25003.1 - 1.7e-20 72.7 0.4 1.3e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAR25003.1 - 6e-15 55.0 17.4 1.1e-14 54.1 12.0 1.5 1 0 0 1 1 1 1 DnaJ central domain Coatomer_WDAD PF04053.9 CAR25003.1 - 4.7e-05 22.3 0.0 7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region HypA PF01155.14 CAR25003.1 - 0.015 15.0 10.3 0.16 11.6 1.1 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Methyltransf_26 PF13659.1 CAR25004.1 - 8.3e-14 51.6 0.0 1.9e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CAR25004.1 - 1.1e-11 44.4 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CAR25004.1 - 2.2e-09 37.0 0.0 3.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR25004.1 - 1e-08 35.7 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CAR25004.1 - 0.00017 21.1 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 CAR25004.1 - 0.00085 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CAR25004.1 - 0.0099 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 CAR25004.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.11 CAR25004.1 - 0.049 12.7 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Gcd10p PF04189.8 CAR25005.1 - 4.3e-102 341.2 0.3 5.4e-102 340.9 0.2 1.1 1 0 0 1 1 1 1 Gcd10p family Nol1_Nop2_Fmu PF01189.12 CAR25006.1 - 3.4e-107 358.0 0.0 1.1e-106 356.3 0.0 1.8 2 0 0 2 2 2 1 NOL1/NOP2/sun family FtsJ PF01728.14 CAR25006.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CAR25006.1 - 0.0015 18.1 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Actin PF00022.14 CAR25007.1 - 1.1e-49 168.9 0.3 8.8e-32 109.9 0.0 2.3 2 0 0 2 2 2 2 Actin MFS_1 PF07690.11 CAR25008.1 - 9.3e-09 34.4 11.7 9.3e-09 34.4 8.1 3.6 1 1 1 3 3 3 3 Major Facilitator Superfamily ketoacyl-synt PF00109.21 CAR25009.1 - 2.5e-20 73.0 0.6 4.5e-20 72.2 0.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CAR25009.1 - 2.8e-12 46.5 0.1 9.2e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 CAR25009.1 - 0.006 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ras PF00071.17 CAR25010.1 - 6.4e-56 188.2 0.0 8.4e-56 187.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR25010.1 - 2.8e-16 60.0 0.0 4.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR25010.1 - 3.2e-10 39.5 0.0 5.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CAR25010.1 - 0.0012 18.7 0.0 0.0049 16.8 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAR25010.1 - 0.0014 17.8 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CAR25010.1 - 0.0021 17.2 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CAR25010.1 - 0.0053 15.4 0.0 0.0061 15.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arch_ATPase PF01637.13 CAR25010.1 - 0.048 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 CAR25010.1 - 0.049 13.9 0.1 0.091 13.0 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Cytochrom_B_N PF00033.14 CAR25011.1 - 0.071 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB ABC2_membrane_3 PF12698.2 CAR25011.1 - 0.59 9.1 4.2 0.28 10.1 0.2 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Y_phosphatase2 PF03162.8 CAR25012.1 - 6.4e-54 181.7 0.0 7e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAR25012.1 - 2.1e-06 28.0 0.0 3.8e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Aminotran_1_2 PF00155.16 CAR25013.1 - 5.3e-61 206.5 0.0 6e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CAR25013.1 - 0.00039 18.8 0.1 0.0015 16.8 0.1 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 CAR25013.1 - 0.0081 14.8 0.0 0.018 13.7 0.0 1.5 1 1 0 1 1 1 1 Allinase Keratin_B2_2 PF13885.1 CAR25014.1 - 0.022 14.4 0.0 1.5 8.5 0.0 3.1 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein Porin_3 PF01459.17 CAR25015.1 - 1.1e-62 211.8 0.3 1.2e-62 211.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin RE_XamI PF09572.5 CAR25015.1 - 0.016 14.7 0.1 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 XamI restriction endonuclease DNA_pol3_beta_3 PF02768.10 CAR25015.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain Vac7 PF12751.2 CAR25016.1 - 2.3e-19 69.5 8.1 1.3e-10 40.7 0.0 3.0 2 1 0 2 2 2 2 Vacuolar segregation subunit 7 DSPc PF00782.15 CAR25017.1 - 7.7e-36 122.6 0.6 1.2e-35 121.9 0.4 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR25017.1 - 2.1e-05 23.9 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CAR25017.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Ank PF00023.25 CAR25018.1 - 2.9e-39 130.9 4.8 1.9e-11 43.1 0.4 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 CAR25018.1 - 9.9e-39 131.5 1.7 2.2e-17 63.1 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CAR25018.1 - 6e-28 96.7 0.1 1.6e-11 44.3 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR25018.1 - 4.6e-27 91.3 0.1 3.5e-08 32.9 0.1 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 CAR25018.1 - 1.2e-24 85.7 1.6 4.2e-07 29.9 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) COX4 PF02936.9 CAR25019.1 - 1e-41 142.0 0.6 1.1e-41 141.8 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.8 CAR25019.1 - 0.72 9.3 2.8 9.3 5.8 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Methyltransf_12 PF08242.7 CAR25020.1 - 0.039 14.4 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain COG5 PF10392.4 CAR25021.1 - 3e-32 111.3 3.4 3e-32 111.3 2.4 3.1 3 1 1 4 4 4 1 Golgi transport complex subunit 5 DUF2011 PF09428.5 CAR25022.1 - 4.6e-34 117.1 14.3 6.5e-34 116.6 9.9 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) bZIP_Maf PF03131.12 CAR25022.1 - 0.61 10.4 8.8 1.6 9.1 6.1 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Sec23_trunk PF04811.10 CAR25023.1 - 2.3e-70 236.7 0.0 4.8e-70 235.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CAR25023.1 - 3.3e-22 77.8 0.1 8.8e-22 76.4 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CAR25023.1 - 1.5e-18 66.0 4.8 2.7e-18 65.2 3.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CAR25023.1 - 1.9e-16 60.3 1.0 9.8e-16 58.0 0.0 2.7 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CAR25023.1 - 3.5e-09 36.2 0.0 7.8e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DUF2229 PF09989.4 CAR25023.1 - 0.017 14.5 0.3 0.033 13.6 0.2 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Metallopep PF12044.3 CAR25024.1 - 8.7e-168 558.1 0.0 1e-167 557.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 CAR25024.1 - 1.1e-05 25.3 1.6 9.3e-05 22.3 1.1 2.3 1 1 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 CAR25024.1 - 0.024 14.5 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CAR25024.1 - 0.026 15.0 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CAR25024.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like 6PF2K PF01591.13 CAR25025.1 - 1.3e-82 276.2 0.3 1.9e-82 275.6 0.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CAR25025.1 - 9.7e-31 106.9 0.3 2.1e-29 102.6 0.0 2.5 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CAR25025.1 - 2.6e-09 37.0 0.0 1.4e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR25025.1 - 1.1e-06 29.4 0.0 4.5e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CAR25025.1 - 0.00076 19.4 0.1 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CAR25025.1 - 0.00093 18.3 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CAR25025.1 - 0.0016 18.7 0.0 0.0064 16.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 CAR25025.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Pox_A28 PF04584.9 CAR25025.1 - 0.034 14.0 0.2 0.074 12.9 0.1 1.6 1 0 0 1 1 1 0 Poxvirus A28 family APS_kinase PF01583.15 CAR25025.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Mob1_phocein PF03637.12 CAR25026.1 - 1.6e-70 236.3 0.3 2e-70 236.0 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glycos_transf_1 PF00534.15 CAR25027.1 - 4.2e-12 45.8 0.0 7.6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CAR25027.1 - 0.04 14.0 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 PH PF00169.24 CAR25028.1 - 8.8e-17 61.2 0.5 2e-16 60.0 0.4 1.6 1 0 0 1 1 1 1 PH domain PRA1 PF03208.14 CAR25030.1 - 4e-39 133.4 3.4 4.5e-39 133.2 2.3 1.0 1 0 0 1 1 1 1 PRA1 family protein IncA PF04156.9 CAR25030.1 - 0.16 11.5 0.1 0.16 11.5 0.1 2.6 3 0 0 3 3 3 0 IncA protein Tic20 PF09685.5 CAR25030.1 - 5.5 7.0 9.9 0.44 10.5 1.7 2.0 1 1 1 2 2 2 0 Tic20-like protein DUF2722 PF10846.3 CAR25031.1 - 7.3e-58 196.5 17.2 3.1e-55 187.8 11.9 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) SHQ1 PF04925.10 CAR25032.1 - 8.7e-75 250.3 1.7 1.4e-74 249.6 1.2 1.3 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.12 CAR25033.1 - 8.4e-114 379.9 0.0 1e-113 379.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COG6 PF06419.6 CAR25034.1 - 1.2e-136 456.4 19.3 1.2e-136 456.4 13.4 1.6 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Pro_CA PF00484.14 CAR25036.1 - 6.4e-39 133.4 0.3 7.8e-39 133.1 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PRAP PF15314.1 CAR25036.1 - 0.022 15.0 0.4 0.046 14.0 0.3 1.5 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine Glyco_hydro_15 PF00723.16 CAR25037.1 - 2.7e-55 187.7 0.0 4e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Complex1_LYR_2 PF13233.1 CAR25038.1 - 2.2e-17 63.4 4.9 4.2e-17 62.5 3.4 1.5 1 1 0 1 1 1 1 Complex1_LYR-like YebO PF13974.1 CAR25038.1 - 0.14 11.9 2.9 0.15 11.8 1.2 1.8 1 1 1 2 2 2 0 YebO-like protein TetR_C_8 PF14278.1 CAR25038.1 - 0.15 12.4 0.4 1.1 9.6 0.0 2.2 1 1 0 2 2 2 0 Transcriptional regulator C-terminal region Iso_dh PF00180.15 CAR25039.1 - 1.6e-79 267.3 0.0 1.8e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CLTH PF10607.4 CAR25040.1 - 7.7e-29 100.2 1.0 7.7e-29 100.2 0.7 2.5 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.10 CAR25040.1 - 0.011 15.6 0.0 0.042 13.8 0.0 2.0 1 0 0 1 1 1 0 U-box domain DUF2431 PF10354.4 CAR25041.1 - 7e-58 195.2 1.5 1.2e-57 194.5 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Band_3_cyto PF07565.8 CAR25041.1 - 0.31 10.4 2.4 0.23 10.9 0.1 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PIG-H PF10181.4 CAR25042.1 - 6e-21 73.8 0.7 1.1e-20 72.9 0.5 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-binding PF00249.26 CAR25043.1 - 2.5e-07 30.6 0.0 7.1e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR25043.1 - 0.044 13.8 1.6 0.21 11.6 0.0 2.7 2 1 0 2 2 2 0 Myb-like DNA-binding domain WD40 PF00400.27 CAR25044.1 - 6.1e-14 51.2 0.3 1.4e-06 27.9 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CAR25044.1 - 0.00056 18.7 0.0 0.53 8.9 0.0 2.4 2 1 0 2 2 2 2 Nup133 N terminal like Pkinase PF00069.20 CAR25045.1 - 9.3e-36 123.3 0.0 1.9e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25045.1 - 4.7e-29 101.2 0.0 6.9e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR25045.1 - 0.0017 17.3 0.0 0.0035 16.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CAR25045.1 - 0.0068 16.1 0.0 0.2 11.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3595 PF12166.3 CAR25045.1 - 0.12 11.1 3.6 1.4 7.6 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3595) Hist_deacetyl PF00850.14 CAR25046.1 - 3e-96 322.3 0.0 4.4e-96 321.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CAR25046.1 - 8.2e-49 165.4 1.1 1.2e-48 164.9 0.8 1.2 1 0 0 1 1 1 1 Arb2 domain Nol1_Nop2_Fmu PF01189.12 CAR25047.1 - 3e-17 62.9 0.1 1.1e-15 57.7 0.1 2.1 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CAR25047.1 - 0.00071 19.5 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Iso_dh PF00180.15 CAR25048.1 - 8e-108 360.4 0.0 9.8e-108 360.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase R3H PF01424.17 CAR25049.1 - 4.9e-12 45.3 0.0 1.1e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 CAR25049.1 - 3.1e-07 30.1 163.8 3.5e-05 23.6 9.2 12.1 11 2 0 11 11 11 7 NF-X1 type zinc finger SLS PF14611.1 CAR25049.1 - 0.022 14.1 0.3 0.037 13.4 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Methyltransf_16 PF10294.4 CAR25050.1 - 3.4e-48 163.3 0.0 4.4e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 CAR25050.1 - 0.019 14.4 0.1 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CAR25050.1 - 0.021 14.1 0.1 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 CAR25050.1 - 0.032 13.8 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CAR25050.1 - 0.16 11.9 0.2 0.22 11.5 0.2 1.3 1 1 0 1 1 1 0 Methyltransferase domain MRP-S25 PF13741.1 CAR25051.1 - 1.6e-91 305.9 5.4 1.9e-91 305.6 3.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 CAR25051.1 - 0.0001 22.1 1.6 0.0034 17.2 0.1 2.7 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S23 DUF1242 PF06842.7 CAR25052.1 - 4.8e-19 67.5 0.7 6.3e-19 67.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF1253 PF06862.7 CAR25053.1 - 2.6e-157 523.7 6.9 3.7e-157 523.2 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 CAR25053.1 - 0.0012 18.3 1.9 0.04 13.3 1.3 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase CDC45 PF02724.9 CAR25053.1 - 0.51 8.3 10.2 1 7.3 7.1 1.5 1 0 0 1 1 1 0 CDC45-like protein ICE2 PF08426.5 CAR25054.1 - 1.9e-163 543.9 23.6 2.2e-163 543.7 16.4 1.0 1 0 0 1 1 1 1 ICE2 Cyclin_N PF00134.18 CAR25055.1 - 1.8e-16 59.8 0.2 3.6e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR25055.1 - 0.0015 18.4 0.8 0.063 13.2 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain PRTase_3 PF15610.1 CAR25055.1 - 0.028 13.3 0.2 0.32 9.8 0.0 2.1 1 1 1 2 2 2 0 PRTase ComF-like TRAM_LAG1_CLN8 PF03798.11 CAR25056.1 - 8.2e-40 136.4 27.6 1.7e-39 135.4 19.1 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 CAR25056.1 - 2e-16 59.2 0.8 2e-16 59.2 0.5 2.4 2 0 0 2 2 2 1 TRAM1-like protein Aa_trans PF01490.13 CAR25057.1 - 4.6e-105 351.4 20.0 5.4e-105 351.2 13.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 60KD_IMP PF02096.15 CAR25057.1 - 0.34 10.5 3.3 0.15 11.6 0.3 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein Y_phosphatase2 PF03162.8 CAR25058.1 - 1.9e-64 215.9 0.0 2.7e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CAR25058.1 - 8.8e-08 32.5 0.0 4.6e-07 30.2 0.0 2.0 1 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CAR25058.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR25058.1 - 0.0027 17.0 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2416 PF10315.4 CAR25059.1 - 1e-38 131.8 3.8 2.3e-38 130.7 2.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Histone PF00125.19 CAR25060.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAR25060.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CAR25060.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAR25060.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CAR25061.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25061.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAR25061.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CAR25061.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CAR25061.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CAR25061.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CAR25061.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CAR25061.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_15 PF01793.11 CAR25062.1 - 2.1e-123 411.4 10.0 2.7e-123 411.1 6.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase AA_permease_2 PF13520.1 CAR25063.1 - 1.9e-68 230.9 53.4 2.3e-68 230.6 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR25063.1 - 1.5e-16 59.8 46.5 2e-16 59.4 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease Shisa PF13908.1 CAR25063.1 - 0.43 10.7 1.3 1.3 9.1 0.9 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sds3 PF08598.6 CAR25064.1 - 4.5e-62 209.2 12.2 6.6e-62 208.6 8.4 1.3 1 0 0 1 1 1 1 Sds3-like BEX PF04538.7 CAR25064.1 - 4.6 7.5 7.7 1.4 9.1 0.8 2.8 2 1 1 3 3 3 0 Brain expressed X-linked like family Met_10 PF02475.11 CAR25065.1 - 7.7e-10 38.6 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CAR25065.1 - 0.0007 19.6 0.0 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CAR25065.1 - 0.0041 16.5 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Filo_VP35 PF02097.10 CAR25065.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Psb28 PF03912.9 CAR25065.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Psb28 protein zf-H2C2_2 PF13465.1 CAR25066.1 - 5.5e-14 51.6 10.1 5e-07 29.7 0.1 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CAR25066.1 - 1.7e-13 50.0 11.2 1.2e-06 28.5 1.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR25066.1 - 4.4e-11 42.2 9.0 0.00012 22.1 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CAR25066.1 - 3.5e-07 30.1 2.4 2.6e-05 24.2 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CAR25066.1 - 9.8e-07 28.7 5.3 0.0008 19.4 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.1 CAR25066.1 - 0.00054 20.1 2.6 0.00054 20.1 1.8 2.0 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain FYVE PF01363.16 CAR25066.1 - 0.31 10.9 5.2 0.56 10.1 3.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.10 CAR25066.1 - 0.58 9.9 6.7 0.94 9.2 0.3 3.1 2 1 1 3 3 3 0 BED zinc finger C1_4 PF07975.7 CAR25066.1 - 2.6 8.1 4.9 39 4.3 3.3 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 CAR25066.1 - 4.3 7.3 7.6 65 3.6 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Bac_surface_Ag PF01103.18 CAR25067.1 - 2.4e-44 152.1 6.6 3e-44 151.8 4.5 1.1 1 0 0 1 1 1 1 Surface antigen DFP PF04127.10 CAR25068.1 - 5.8e-16 58.6 0.0 1.2e-06 28.3 0.0 2.9 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Na_H_Exchanger PF00999.16 CAR25069.1 - 9.6e-63 211.9 32.2 1.4e-62 211.4 22.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ATP12 PF07542.6 CAR25069.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP12 chaperone protein DUF4131 PF13567.1 CAR25069.1 - 0.9 8.9 8.9 3.4 7.0 1.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_1 PF00076.17 CAR25070.1 - 1.3e-53 178.4 0.5 5.4e-19 67.5 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR25070.1 - 1.4e-32 111.5 0.4 1.2e-10 41.2 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR25070.1 - 2.7e-23 81.5 1.5 1.4e-08 34.4 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR25070.1 - 0.025 14.3 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif UCH PF00443.24 CAR25071.1 - 1.8e-48 164.9 0.5 2.5e-48 164.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR25071.1 - 1.7e-12 47.3 2.4 6.2e-06 25.8 0.0 3.5 2 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Roughex PF06020.6 CAR25071.1 - 0.0053 15.4 0.2 0.012 14.3 0.2 1.5 1 0 0 1 1 1 1 Drosophila roughex protein DUF1528 PF07515.6 CAR25071.1 - 0.03 14.3 0.8 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) DUF4318 PF14201.1 CAR25072.1 - 0.067 13.0 0.1 0.13 12.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4318) DUF4320 PF14208.1 CAR25072.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Frataxin_Cyay PF01491.11 CAR25073.1 - 4.2e-34 116.6 0.0 5.1e-34 116.3 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Glyco_hydro_38 PF01074.17 CAR25074.1 - 2.3e-83 279.6 0.3 3.6e-83 278.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CAR25074.1 - 1e-68 232.2 1.3 1.4e-68 231.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CAR25074.1 - 1.8e-22 79.3 0.0 4.1e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Rhamnogal_lyase PF06045.6 CAR25074.1 - 0.0013 18.0 0.2 0.0025 17.1 0.2 1.3 1 0 0 1 1 1 1 Rhamnogalacturonate lyase family Prenyltrans PF00432.16 CAR25075.1 - 1.7e-28 97.8 2.7 5.9e-08 32.1 0.0 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CAR25075.1 - 1.3e-12 48.0 0.0 0.00027 21.3 0.0 3.3 3 1 1 4 4 4 3 Prenyltransferase-like Mito_carr PF00153.22 CAR25076.1 - 4.1e-53 177.0 0.8 2.1e-20 72.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ACPS PF01648.15 CAR25077.1 - 3.5e-10 39.6 0.0 9.3e-10 38.3 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Pex14_N PF04695.8 CAR25078.1 - 6.2e-33 113.7 0.3 6.2e-33 113.7 0.2 3.0 3 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.7 CAR25078.1 - 0.0016 18.2 0.5 0.0016 18.2 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) HemX PF04375.9 CAR25078.1 - 0.0027 16.3 0.7 0.0056 15.3 0.5 1.5 1 0 0 1 1 1 1 HemX IncA PF04156.9 CAR25078.1 - 0.013 15.0 5.3 0.021 14.4 3.7 1.3 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 CAR25078.1 - 0.014 14.3 1.1 0.018 13.9 0.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 CAR25078.1 - 0.11 11.5 0.2 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein EAP30 PF04157.11 CAR25078.1 - 0.29 10.2 7.1 0.33 10.0 4.1 1.6 1 1 0 1 1 1 0 EAP30/Vps36 family APG6 PF04111.7 CAR25078.1 - 2.9 6.8 11.8 6.1 5.7 8.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Med5 PF08689.5 CAR25079.1 - 4e-201 670.3 32.5 4.5e-201 670.1 22.5 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SNF2_N PF00176.18 CAR25080.1 - 1.3e-70 237.5 1.5 1.3e-70 237.5 1.1 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 CAR25080.1 - 1.4e-53 180.7 23.4 1.4e-53 180.7 16.2 3.9 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 CAR25080.1 - 1.3e-13 50.5 1.2 3.6e-13 49.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TFIIA PF03153.8 CAR25080.1 - 0.0063 16.4 30.2 0.0063 16.4 20.9 2.8 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Fe_hyd_lg_C PF02906.9 CAR25080.1 - 0.016 14.4 0.3 0.039 13.2 0.2 1.6 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Sugar_tr PF00083.19 CAR25081.1 - 8.4e-86 288.3 23.1 1.2e-85 287.8 16.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR25081.1 - 1.3e-31 109.6 25.1 1.3e-31 109.6 17.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR25081.1 - 0.0002 19.6 5.3 0.0002 19.6 3.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) RTP801_C PF07809.6 CAR25081.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 RTP801 C-terminal region DUF4097 PF13349.1 CAR25081.1 - 0.39 10.2 3.1 11 5.5 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4097) YrhK PF14145.1 CAR25081.1 - 0.75 9.4 7.4 17 5.1 2.2 3.3 2 0 0 2 2 2 0 YrhK-like protein AMP-binding PF00501.23 CAR25083.1 - 1.3e-87 293.9 0.1 1.6e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR25083.1 - 7e-19 68.5 1.4 1.2e-18 67.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Mem_trans PF03547.13 CAR25084.1 - 2.5e-56 190.6 0.0 8.9e-56 188.8 0.0 1.8 1 1 0 1 1 1 1 Membrane transport protein NUDIX PF00293.23 CAR25085.1 - 3.2e-12 46.2 0.0 4.6e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain Stm1_N PF09598.5 CAR25086.1 - 8e-18 64.9 6.5 8e-18 64.9 4.5 4.4 2 1 1 4 4 4 1 Stm1 RdRP_4 PF02123.11 CAR25086.1 - 0.033 12.9 1.6 0.038 12.7 1.1 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase ARD PF03079.9 CAR25086.1 - 0.36 10.7 4.5 0.14 12.1 1.1 1.7 1 1 1 2 2 2 0 ARD/ARD' family CAML PF14963.1 CAR25086.1 - 3 7.1 5.3 4 6.7 3.7 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PDE6_gamma PF04868.7 CAR25086.1 - 5.5 6.9 9.7 1.3 8.9 0.5 3.4 3 1 1 4 4 4 0 Retinal cGMP phosphodiesterase, gamma subunit Stb3 PF10330.4 CAR25087.1 - 1.2e-30 105.0 0.0 2.3e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF2415 PF10313.4 CAR25088.1 - 2.6e-22 78.2 0.2 3.2e-21 74.7 0.5 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) CDC37_N PF03234.9 CAR25089.1 - 1.2e-65 221.1 9.7 1.2e-65 221.1 6.7 2.5 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 CAR25089.1 - 4e-45 153.3 3.2 1.1e-44 151.9 2.2 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 CAR25089.1 - 4.3e-23 81.0 3.4 4.3e-23 81.0 2.4 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF1241 PF06840.6 CAR25089.1 - 0.024 13.8 0.9 0.024 13.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Thg1C PF14413.1 CAR25089.1 - 0.62 9.7 4.5 0.39 10.4 0.1 2.9 3 1 0 3 3 3 0 Thg1 C terminal domain ApoC-I PF04691.7 CAR25089.1 - 2.5 7.8 6.6 2.6 7.8 0.1 3.7 4 0 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) TFIID_30kDa PF03540.8 CAR25090.1 - 1.2e-27 95.4 0.2 1.8e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 CAR25090.1 - 0.055 13.1 0.2 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Bromodomain associated E_Pc_C PF06752.7 CAR25090.1 - 0.16 11.4 5.4 0.23 10.9 3.7 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Pep3_Vps18 PF05131.9 CAR25091.1 - 1.9e-38 131.1 0.0 1.2e-37 128.5 0.0 2.3 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CAR25091.1 - 1.3e-05 24.8 0.1 1.3e-05 24.8 0.1 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CAR25091.1 - 0.0037 17.4 1.2 0.0071 16.5 0.1 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 CAR25091.1 - 0.0045 16.8 7.3 0.013 15.2 5.1 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR25091.1 - 0.0056 16.3 2.7 0.0056 16.3 1.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CAR25091.1 - 0.079 12.6 2.7 0.25 11.0 1.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR25091.1 - 7.1 6.7 13.0 0.027 14.5 2.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LSM PF01423.17 CAR25092.1 - 2e-13 49.6 0.1 2.4e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain Sec5 PF15469.1 CAR25093.1 - 1.2e-48 165.2 1.4 1.2e-48 165.2 0.9 2.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 CAR25093.1 - 0.012 15.3 2.0 0.047 13.5 1.4 2.1 1 0 0 1 1 1 0 Vps51/Vps67 Microtub_assoc PF07989.6 CAR25094.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Microtubule associated COG2 PF06148.6 CAR25094.1 - 0.04 13.7 0.1 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 CAR25094.1 - 0.064 12.8 1.0 0.074 12.6 0.7 1.1 1 0 0 1 1 1 0 IncA protein Fez1 PF06818.10 CAR25094.1 - 0.096 12.7 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Fez1 DUF2587 PF10759.4 CAR25094.1 - 0.099 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) FlxA PF14282.1 CAR25094.1 - 1.8 8.5 6.0 0.4 10.6 1.8 1.6 1 1 1 2 2 2 0 FlxA-like protein PQQ_2 PF13360.1 CAR25095.1 - 0.013 14.9 0.1 0.17 11.3 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain WD40 PF00400.27 CAR25095.1 - 0.024 14.5 1.3 3 7.8 0.2 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.1 CAR25095.1 - 0.033 14.4 0.0 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain CPSF_A PF03178.10 CAR25095.1 - 0.049 12.7 0.0 0.19 10.7 0.0 1.8 1 1 1 2 2 2 0 CPSF A subunit region Spermine_synth PF01564.12 CAR25096.1 - 5.9e-89 297.2 0.1 7e-89 296.9 0.1 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 CAR25096.1 - 0.00021 21.2 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR25096.1 - 0.00037 20.0 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR25096.1 - 0.00059 20.4 0.0 0.00096 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR25096.1 - 0.03 13.6 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 CAR25096.1 - 0.053 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1542 PF07564.6 CAR25097.1 - 0.0024 17.8 3.5 0.0049 16.8 2.4 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) DUF310 PF03750.8 CAR25097.1 - 0.032 14.4 0.0 0.095 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF4477 PF14780.1 CAR25097.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4477) Glyco_hydro_81 PF03639.8 CAR25098.1 - 1.3e-234 780.3 20.0 1.6e-234 780.0 13.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 PPC PF04151.10 CAR25098.1 - 0.018 16.0 0.8 0.11 13.5 0.5 2.4 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Sec1 PF00995.18 CAR25099.1 - 4.5e-94 316.0 0.0 5.3e-94 315.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family P53_C PF11619.3 CAR25100.1 - 0.073 12.8 0.1 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain ATP_bind_4 PF01902.12 CAR25101.1 - 5e-32 111.0 0.0 1.6e-31 109.3 0.0 1.8 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 CAR25101.1 - 1.1e-14 54.2 0.0 1.5e-09 37.6 0.0 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP Aldolase_2 PF10120.4 CAR25101.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative aldolase Pro_dh PF01619.13 CAR25102.1 - 3.4e-57 193.7 0.0 4.8e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase DUF1779 PF08680.5 CAR25103.1 - 0.042 13.7 0.5 0.078 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) SLS PF14611.1 CAR25104.1 - 1.7e-26 92.9 0.1 3.3e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator SH3_9 PF14604.1 CAR25105.1 - 5.5e-13 48.2 0.1 9.9e-13 47.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR25105.1 - 9.9e-12 44.0 0.0 2.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CAR25105.1 - 1.7e-06 27.3 0.1 4.9e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain TPR_2 PF07719.12 CAR25106.1 - 5.8e-08 32.0 0.9 0.069 13.1 0.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CAR25106.1 - 1e-07 31.5 0.2 0.0036 16.9 0.2 2.9 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 CAR25106.1 - 1.4e-07 31.7 0.3 0.00042 20.5 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR25106.1 - 3.8e-07 30.6 0.0 0.00069 20.2 0.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAR25106.1 - 1.8e-06 27.3 0.0 0.11 12.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR25106.1 - 8.6e-06 25.9 0.0 0.55 11.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CAR25106.1 - 1.2e-05 24.7 0.1 0.14 11.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CAR25106.1 - 0.00031 20.6 0.0 2.9 8.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CAR25106.1 - 0.0012 18.5 0.0 1.3 8.9 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR25106.1 - 0.0015 18.5 0.1 0.38 10.9 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CAR25106.1 - 0.0024 17.7 0.0 5 7.1 0.1 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat Rapamycin_bind PF08771.6 CAR25106.1 - 0.012 15.6 0.1 0.14 12.2 0.0 2.5 2 0 0 2 2 2 0 Rapamycin binding domain TPR_15 PF13429.1 CAR25106.1 - 0.049 12.6 0.4 1.4 7.9 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat YfdX PF10938.3 CAR25106.1 - 0.068 12.8 0.1 0.42 10.2 0.1 2.1 2 0 0 2 2 2 0 YfdX protein AA_permease PF00324.16 CAR25107.1 - 5.2e-79 265.8 36.4 7.5e-79 265.2 25.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR25107.1 - 1.4e-22 79.8 41.1 4.9e-22 78.0 28.5 1.7 1 1 0 1 1 1 1 Amino acid permease Nha1_C PF08619.5 CAR25108.1 - 2.7e-75 254.2 47.6 8.5e-74 249.3 33.0 2.0 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 CAR25108.1 - 1.1e-74 251.2 24.7 1.3e-74 251.0 17.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2407_C PF13373.1 CAR25108.1 - 0.62 9.9 2.3 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain SAC3_GANP PF03399.11 CAR25109.1 - 3.4e-55 186.7 0.1 6.1e-55 185.9 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 CAR25109.1 - 4e-13 49.3 1.1 4e-13 49.3 0.8 2.6 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain TMEM247 PF15444.1 CAR25109.1 - 0.023 14.4 2.9 0.072 12.9 2.0 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 Methyltransf_16 PF10294.4 CAR25110.1 - 1e-05 25.0 0.8 0.0055 16.1 0.1 2.4 1 1 1 2 2 2 2 Putative methyltransferase Semialdhyde_dhC PF02774.13 CAR25111.1 - 1.1e-40 139.5 0.0 1.5e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CAR25111.1 - 1.7e-30 105.8 0.0 2.8e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CAR25111.1 - 0.026 15.0 0.0 0.08 13.4 0.0 1.9 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 CAR25111.1 - 0.029 14.2 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 CAR25111.1 - 0.063 12.2 0.1 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase RNA_polI_A14 PF08203.6 CAR25112.1 - 2.1e-18 66.3 0.1 7.5e-18 64.5 0.1 1.7 1 1 0 1 1 1 1 Yeast RNA polymerase I subunit RPA14 Pro_isomerase PF00160.16 CAR25113.1 - 8.8e-47 159.1 0.0 9.6e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 CAR25114.1 - 2.6e-30 104.8 0.1 3.9e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain Nop53 PF07767.6 CAR25114.1 - 0.15 11.0 8.2 0.22 10.4 5.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PGA2 PF07543.7 CAR25114.1 - 0.34 10.6 9.4 0.035 13.8 3.2 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 RWD PF05773.17 CAR25115.1 - 1.3e-26 92.6 4.5 1.3e-26 92.6 3.1 1.7 2 0 0 2 2 2 1 RWD domain PP_M1 PF03012.9 CAR25115.1 - 0.041 13.2 4.0 0.059 12.7 2.8 1.2 1 0 0 1 1 1 0 Phosphoprotein GOLD_2 PF13897.1 CAR25115.1 - 3.7 7.7 6.4 4.8 7.4 0.2 2.2 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking BNR_2 PF13088.1 CAR25116.1 - 0.00083 18.7 0.0 0.71 9.1 0.0 3.3 1 1 0 3 3 3 2 BNR repeat-like domain BNR PF02012.15 CAR25116.1 - 0.0016 17.9 26.5 0.039 13.7 0.9 5.9 7 0 0 7 7 7 4 BNR/Asp-box repeat Mo-co_dimer PF03404.11 CAR25116.1 - 0.19 11.3 0.0 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 CAR25117.1 - 8.4e-07 27.9 10.7 0.069 12.9 0.5 5.0 4 0 0 4 4 4 4 BNR/Asp-box repeat BNR PF02012.15 CAR25118.1 - 4.2e-05 22.7 5.9 0.38 10.7 0.2 4.5 5 0 0 5 5 5 2 BNR/Asp-box repeat DUF4185 PF13810.1 CAR25118.1 - 0.0085 15.0 3.6 1 8.1 0.1 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4185) BNR_3 PF13859.1 CAR25118.1 - 0.017 14.2 0.1 0.044 12.8 0.0 1.8 2 0 0 2 2 2 0 BNR repeat-like domain BNR PF02012.15 CAR25119.1 - 3.4e-05 23.0 18.7 0.86 9.6 0.2 7.0 7 0 0 7 7 7 3 BNR/Asp-box repeat BNR_2 PF13088.1 CAR25119.1 - 0.00056 19.2 2.4 1.7 7.8 0.0 4.1 4 2 0 4 4 4 2 BNR repeat-like domain PSII_BNR PF14870.1 CAR25119.1 - 0.0033 16.4 0.2 0.19 10.7 0.0 3.1 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.11 CAR25119.1 - 0.085 12.4 0.8 24 4.5 0.0 4.1 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain zf-CCCH PF00642.19 CAR25121.1 - 1.4e-18 66.0 17.4 2.1e-09 36.8 2.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CAR25121.1 - 0.12 12.4 13.0 0.28 11.2 1.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHH PF10283.4 CAR25121.1 - 3.3 7.6 11.0 8.3 6.3 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif Peptidase_M28 PF04389.12 CAR25122.1 - 1.5e-16 60.6 0.0 2.7e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CAR25122.1 - 4.7e-14 52.0 0.0 8e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CAR25122.1 - 3.4e-08 33.0 0.1 7.3e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 CAR25122.1 - 0.0014 17.9 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.23 CAR25122.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Mcp5_PH PF12814.2 CAR25123.1 - 5.2e-41 139.4 0.1 1.3e-40 138.1 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ADIP PF11559.3 CAR25123.1 - 1.6e-05 24.8 8.7 1.6e-05 24.8 6.0 4.8 4 1 0 5 5 5 2 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 CAR25123.1 - 0.013 14.8 15.6 0.46 9.8 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF2567 PF10821.3 CAR25123.1 - 0.068 12.6 0.0 1.8e+02 1.5 0.0 4.9 3 3 2 5 5 5 0 Protein of unknown function (DUF2567) DUF972 PF06156.8 CAR25123.1 - 0.29 11.4 23.6 0.3 11.4 3.7 4.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) FUSC PF04632.7 CAR25123.1 - 2.7 6.3 3.4 4.4 5.6 2.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 CAR25123.1 - 3.4 7.2 30.8 0.88 9.1 6.0 3.8 1 1 1 2 2 2 0 IncA protein Slx4 PF09494.5 CAR25124.1 - 2.1e-17 62.6 0.2 9.5e-17 60.5 0.0 2.2 2 0 0 2 2 2 1 Slx4 endonuclease 2-oxoacid_dh PF00198.18 CAR25125.1 - 3.1e-81 272.0 0.1 5.2e-81 271.3 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CAR25125.1 - 5.8e-17 61.1 0.5 1.1e-16 60.2 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CAR25125.1 - 0.00031 20.3 0.1 0.0036 16.9 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 CAR25125.1 - 0.0015 18.8 0.1 0.018 15.3 0.0 2.3 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 CAR25125.1 - 0.0024 17.5 0.0 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.2 CAR25125.1 - 0.0031 16.7 0.1 0.053 12.6 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 CAR25125.1 - 0.0033 17.0 0.2 0.011 15.4 0.1 1.8 1 1 0 1 1 1 1 Glycine cleavage H-protein Ndc1_Nup PF09531.5 CAR25125.1 - 0.75 8.1 3.4 1 7.6 2.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 CAR25125.1 - 1.4 7.0 8.6 1.6 6.8 5.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Choline_kinase PF01633.15 CAR25126.1 - 2.3e-63 213.5 0.0 3.2e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CAR25126.1 - 4.3e-12 46.2 0.0 9e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kin_N PF04428.9 CAR25126.1 - 2.1e-11 43.1 0.0 5.4e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus HVSL PF09749.4 CAR25127.1 - 2.2e-27 95.6 0.1 3.2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein zf-C2H2 PF00096.21 CAR25128.1 - 1.3e-09 37.7 17.2 0.00073 19.7 1.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR25128.1 - 1e-05 25.5 13.3 0.024 14.9 1.0 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR25128.1 - 0.0051 17.0 0.1 0.0051 17.0 0.1 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CAR25128.1 - 1.2 9.1 7.8 23 5.0 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR25128.1 - 1.8 8.7 6.1 39 4.5 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding WD40 PF00400.27 CAR25129.1 - 4.2e-71 232.5 32.3 2.3e-09 36.7 0.2 11.0 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 CAR25129.1 - 2.3e-21 75.7 0.1 4.9e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CAR25129.1 - 3.8e-08 31.9 8.0 0.0045 15.1 0.0 5.4 5 2 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR25129.1 - 2.2e-06 26.7 10.0 1.2 7.7 0.1 6.0 3 2 1 4 4 4 4 Nup133 N terminal like eIF2A PF08662.6 CAR25129.1 - 9.5e-05 22.1 1.0 0.17 11.5 0.0 4.3 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 CAR25129.1 - 0.015 14.5 1.4 2.6 7.2 0.0 3.4 3 0 0 3 3 3 0 TUP1-like enhancer of split Phage_HK97_TLTM PF06120.6 CAR25129.1 - 0.7 9.1 2.8 1.8 7.8 0.1 2.6 3 0 0 3 3 3 0 Tail length tape measure protein TFIID_20kDa PF03847.8 CAR25130.1 - 1.5e-32 111.6 0.5 2.8e-32 110.8 0.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CAR25130.1 - 0.0014 18.6 0.0 0.0042 17.1 0.0 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25130.1 - 0.064 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cullin_binding PF03556.10 CAR25131.1 - 1.1e-31 109.3 3.0 2.4e-31 108.2 2.1 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 CAR25131.1 - 2.2e-10 39.8 2.0 2.9e-10 39.4 0.3 2.0 2 0 0 2 2 2 1 UBA-like domain Cullin PF00888.17 CAR25132.1 - 9.8e-27 93.7 3.5 9.8e-27 93.7 2.4 1.8 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 CAR25132.1 - 1.3e-18 66.9 0.0 4.9e-18 65.1 0.0 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 HTH_9 PF08221.6 CAR25132.1 - 5.4e-05 22.9 0.3 0.00066 19.5 0.0 3.0 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain Stork_head PF10264.4 CAR25132.1 - 0.015 15.4 0.2 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Linker_histone PF00538.14 CAR25132.1 - 0.052 13.6 0.0 0.89 9.7 0.1 2.9 3 0 0 3 3 3 0 linker histone H1 and H5 family GATase PF00117.23 CAR25133.1 - 2.4e-11 43.4 0.1 3e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Asp PF00026.18 CAR25134.1 - 9.8e-70 235.2 12.4 9.8e-70 235.2 8.6 2.6 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CAR25134.1 - 1.3e-08 34.9 0.0 4.2e-07 30.0 0.0 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CAR25134.1 - 0.0035 16.9 0.9 0.39 10.2 0.6 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CAR25134.1 - 0.021 15.3 4.2 9 6.8 0.1 4.1 4 0 0 4 4 4 0 Aspartyl protease zf-RING_2 PF13639.1 CAR25135.1 - 8.1e-13 47.9 6.9 1.6e-11 43.8 1.5 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 CAR25135.1 - 2.5e-09 37.1 2.7 7e-07 29.2 0.6 2.4 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CAR25135.1 - 3.9e-06 26.4 3.2 7.3e-06 25.5 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR25135.1 - 8.3e-06 25.7 7.9 3.3e-05 23.7 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR25135.1 - 1.3e-05 24.7 5.4 1.6e-05 24.4 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR25135.1 - 1.4e-05 24.7 4.6 2.6e-05 23.8 0.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CAR25135.1 - 4.2e-05 23.1 1.8 4.2e-05 23.1 1.3 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CAR25135.1 - 0.0002 21.1 1.2 0.0002 21.1 0.9 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CAR25135.1 - 0.0052 16.2 0.7 0.0052 16.2 0.5 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 CAR25135.1 - 0.021 14.6 0.7 0.13 12.0 0.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 CAR25135.1 - 0.023 13.8 10.6 0.053 12.7 0.0 2.6 2 1 1 3 3 3 0 Rtf2 RING-finger FANCL_C PF11793.3 CAR25135.1 - 1.2 9.1 3.5 13 5.8 0.0 2.9 2 1 1 3 3 3 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CAR25135.1 - 1.3 8.6 4.8 0.91 9.1 1.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain WD40 PF00400.27 CAR25136.1 - 7e-28 95.4 15.8 2.7e-07 30.1 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Ribosomal_S7 PF00177.16 CAR25136.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Mod_r PF07200.8 CAR25137.1 - 3.7e-17 62.6 10.5 5e-17 62.2 7.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Alpha-2-MRAP_N PF06400.6 CAR25137.1 - 0.052 13.2 2.0 0.072 12.7 1.4 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain DUF342 PF03961.8 CAR25137.1 - 0.17 10.3 1.8 0.19 10.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Abhydrolase_2 PF02230.11 CAR25138.1 - 4.5e-61 206.0 0.0 5e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CAR25138.1 - 1.5e-13 50.7 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR25138.1 - 3.9e-10 39.9 0.1 6.4e-09 36.0 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 CAR25138.1 - 1.3e-09 37.8 0.0 3e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 CAR25138.1 - 1.7e-05 24.1 0.0 2.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 CAR25138.1 - 0.0018 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CAR25138.1 - 0.019 14.1 0.1 2.3 7.4 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family Fe_dep_repr_C PF02742.10 CAR25138.1 - 0.026 14.2 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Lipase_3 PF01764.20 CAR25138.1 - 0.047 13.2 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 CAR25138.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Phi-29_GP3 PF05435.6 CAR25138.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 BAAT_C PF08840.6 CAR25138.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 CAR25138.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase Cutinase PF01083.17 CAR25138.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase Dopey_N PF04118.9 CAR25139.1 - 2.6e-116 387.7 1.6 3.4e-116 387.3 0.2 1.9 2 0 0 2 2 2 1 Dopey, N-terminal Methyltransf_26 PF13659.1 CAR25140.1 - 6.6e-12 45.4 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR25140.1 - 1.7e-07 30.8 0.0 2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CAR25140.1 - 0.0017 18.0 0.0 0.067 12.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR25140.1 - 0.01 15.4 0.0 0.028 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CAR25140.1 - 0.011 14.9 0.0 0.072 12.1 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 CAR25140.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_18 PF12847.2 CAR25140.1 - 0.074 13.6 0.0 0.36 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.18 CAR25141.1 - 2.1e-22 78.3 0.2 2.3e-22 78.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CAR25141.1 - 1.7e-16 59.6 0.2 1.8e-16 59.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CAR25141.1 - 0.00012 22.2 0.1 0.00037 20.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TUG-UBL1 PF11470.3 CAR25141.1 - 0.00078 19.3 0.0 0.00081 19.2 0.0 1.2 1 0 0 1 1 1 1 GLUT4 regulating protein TUG TPR_14 PF13428.1 CAR25142.1 - 6.4e-19 66.7 7.3 0.26 12.0 0.2 9.9 6 3 4 10 10 10 4 Tetratricopeptide repeat HAT PF02184.11 CAR25142.1 - 1.8e-14 53.1 29.2 1.7e-05 24.4 0.5 7.2 7 0 0 7 7 7 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 CAR25142.1 - 2.3e-10 40.6 2.2 0.0037 17.5 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR25142.1 - 4e-09 36.8 10.8 0.0077 16.8 0.4 6.4 5 2 3 8 8 8 3 Tetratricopeptide repeat Suf PF05843.9 CAR25142.1 - 5.4e-06 26.3 11.0 0.099 12.3 0.1 5.6 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_17 PF13431.1 CAR25142.1 - 7.2e-06 25.7 6.9 2.4 8.5 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR25142.1 - 1.1e-05 25.2 7.0 4 7.4 0.2 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 CAR25142.1 - 9.2e-05 21.6 6.7 0.0019 17.3 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CAR25142.1 - 0.0017 18.0 14.1 0.017 14.8 2.3 5.7 4 2 2 6 6 6 1 U3 small nucleolar RNA-associated protein 6 TPR_11 PF13414.1 CAR25142.1 - 0.0025 17.4 12.8 1.8 8.2 0.0 6.4 6 2 1 7 7 7 2 TPR repeat TPR_2 PF07719.12 CAR25142.1 - 0.17 11.8 15.0 4.3 7.5 0.3 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR25142.1 - 0.54 10.1 12.7 3.4 7.6 0.1 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR25142.1 - 2.5 8.7 12.1 31 5.3 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat KH_1 PF00013.24 CAR25143.1 - 4.9e-06 26.1 0.1 1.3e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CAR25143.1 - 1.1e-05 24.9 0.4 3e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 KH domain zf-CCHC_3 PF13917.1 CAR25143.1 - 6.3e-05 22.6 6.5 0.0038 16.9 1.4 2.5 1 1 1 2 2 2 2 Zinc knuckle DUF1660 PF07874.6 CAR25143.1 - 0.08 13.2 0.7 0.2 11.9 0.5 1.6 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-CCHC PF00098.18 CAR25143.1 - 0.11 12.5 8.7 1.7 8.7 1.4 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 CAR25143.1 - 0.51 9.8 6.0 0.16 11.5 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CAR25143.1 - 1.5 8.5 5.2 2.2 8.0 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle CPSF100_C PF13299.1 CAR25144.1 - 1.7e-31 109.5 0.5 1.7e-31 109.5 0.3 3.3 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CAR25144.1 - 3.9e-12 46.1 0.1 2.4e-11 43.6 0.0 2.4 1 1 1 2 2 2 1 Beta-Casp domain Rep_fac-A_3 PF08661.6 CAR25144.1 - 0.032 14.1 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Replication factor A protein 3 efThoc1 PF11957.3 CAR25145.1 - 1.6e-54 185.2 5.4 2.7e-54 184.4 3.8 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Avl9 PF09794.4 CAR25146.1 - 1.6e-144 481.0 0.1 1.6e-144 481.0 0.1 1.5 2 0 0 2 2 2 1 Transport protein Avl9 DUF2347 PF09804.4 CAR25146.1 - 2.9e-06 26.7 8.4 0.13 11.5 0.1 3.8 4 1 0 4 4 4 3 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 CAR25146.1 - 3.1e-06 26.8 0.0 0.041 13.5 0.0 2.6 2 0 0 2 2 2 2 Stabilization of polarity axis DENN PF02141.16 CAR25146.1 - 0.038 13.7 0.3 0.47 10.1 0.1 2.2 1 1 0 2 2 2 0 DENN (AEX-3) domain Afi1 PF07792.7 CAR25146.1 - 0.056 13.4 2.2 0.14 12.1 0.1 2.6 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Rgp1 PF08737.5 CAR25147.1 - 6.8e-70 236.2 3.6 1.1e-69 235.5 2.5 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 CAR25147.1 - 0.034 14.2 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain ABC_membrane PF00664.18 CAR25148.1 - 3.7e-89 298.8 37.8 5.8e-49 166.9 6.4 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CAR25148.1 - 8.8e-50 168.5 0.0 6.7e-31 107.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CAR25148.1 - 7.1e-10 38.4 5.8 0.0016 17.7 0.1 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CAR25148.1 - 9.4e-09 35.5 1.6 0.0027 17.7 0.1 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 CAR25148.1 - 1.4e-06 28.4 0.8 0.36 10.7 0.1 4.6 2 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 CAR25148.1 - 2.5e-06 26.9 0.3 0.014 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CAR25148.1 - 7.7e-06 25.8 0.2 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 CAR25148.1 - 0.00019 21.8 4.8 0.0062 16.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 CAR25148.1 - 0.00024 20.3 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CAR25148.1 - 0.00037 20.9 2.2 0.29 11.6 0.0 3.4 3 0 0 3 3 2 1 Miro-like protein AAA_25 PF13481.1 CAR25148.1 - 0.00047 19.6 0.1 0.84 8.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CAR25148.1 - 0.0027 17.1 5.9 2.3 7.5 0.2 3.8 4 0 0 4 4 4 1 AAA-like domain T2SE PF00437.15 CAR25148.1 - 0.008 15.1 0.1 0.98 8.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 CAR25148.1 - 0.011 15.8 0.9 2 8.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CAR25148.1 - 0.012 15.0 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 CAR25148.1 - 0.014 15.1 0.6 5.2 6.7 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 CAR25148.1 - 0.02 13.9 0.9 1 8.4 0.1 3.0 3 0 0 3 3 3 0 AIG1 family Dynamin_N PF00350.18 CAR25148.1 - 0.021 14.6 2.5 0.27 11.0 0.2 2.6 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 CAR25148.1 - 0.026 14.2 1.2 0.47 10.1 0.0 3.2 4 0 0 4 4 3 0 Archaeal ATPase DUF87 PF01935.12 CAR25148.1 - 0.049 13.4 4.9 0.38 10.5 0.0 3.1 3 0 0 3 3 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 CAR25148.1 - 0.052 12.6 0.4 3.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 CAR25148.1 - 0.061 14.1 0.2 3.2 8.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAR25148.1 - 0.13 11.7 0.2 35 3.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 CAR25148.1 - 0.38 10.5 1.4 1.4 8.7 0.1 2.6 3 0 0 3 3 3 0 Part of AAA domain Pkinase PF00069.20 CAR25149.1 - 3e-70 236.3 0.0 4.6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25149.1 - 1.1e-30 106.5 0.0 1.8e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CAR25149.1 - 3.1e-05 23.1 0.1 0.00012 21.2 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CAR25149.1 - 0.00028 19.9 0.0 0.075 11.9 0.0 2.3 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 CAR25149.1 - 0.00047 19.9 4.5 0.0018 18.0 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 CAR25149.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Flocculin_t3 PF13928.1 CAR25150.1 - 5.7e-16 58.3 15.5 5.7e-16 58.3 10.7 3.1 3 1 0 3 3 3 1 Flocculin type 3 repeat CPSF_A PF03178.10 CAR25150.1 - 0.029 13.4 0.1 0.031 13.3 0.1 1.0 1 0 0 1 1 1 0 CPSF A subunit region BTB_2 PF02214.17 CAR25151.1 - 1.3e-05 25.3 0.0 0.0036 17.4 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain F-box PF00646.28 CAR25152.1 - 0.0002 20.9 0.8 0.00076 19.0 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CAR25152.1 - 0.0012 18.5 0.2 0.003 17.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like RSS_P20 PF11757.3 CAR25152.1 - 0.013 15.6 0.5 0.74 9.9 0.1 2.5 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like AKNA PF12443.3 CAR25153.1 - 0.057 13.4 3.2 0.29 11.1 2.0 2.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor Oest_recep PF02159.10 CAR25153.1 - 0.27 11.3 3.6 0.64 10.1 2.5 1.7 1 0 0 1 1 1 0 Oestrogen receptor RNase_T PF00929.19 CAR25154.1 - 1.7e-17 64.1 0.1 4e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CAR25154.1 - 5e-05 22.8 0.1 0.00041 19.8 0.1 2.3 1 1 0 1 1 1 1 3'-5' exonuclease AAA_5 PF07728.9 CAR25155.1 - 5.2e-132 434.4 0.1 1.1e-21 77.0 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAR25155.1 - 1.6e-33 115.0 0.0 4e-11 42.6 0.0 7.9 8 0 0 8 8 7 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CAR25155.1 - 2.1e-30 105.6 0.0 2.9e-05 24.2 0.0 7.3 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAR25155.1 - 2.6e-22 79.0 0.0 4.1e-05 23.1 0.0 6.0 6 0 0 6 6 5 5 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CAR25155.1 - 6.5e-22 78.0 1.5 3.8e-05 23.7 0.0 7.5 7 0 0 7 7 7 3 Sigma-54 interaction domain AAA_14 PF13173.1 CAR25155.1 - 2e-20 72.9 0.1 0.0018 18.1 0.0 8.1 7 1 0 7 7 7 4 AAA domain AAA_17 PF13207.1 CAR25155.1 - 2.3e-19 70.3 17.9 0.0028 18.4 0.0 8.2 8 0 0 8 8 6 5 AAA domain AAA_16 PF13191.1 CAR25155.1 - 1.7e-17 63.9 14.8 0.0011 19.0 0.0 8.4 8 0 0 8 8 6 4 AAA ATPase domain AAA_33 PF13671.1 CAR25155.1 - 8.6e-17 61.3 0.0 0.072 12.9 0.0 7.3 6 1 0 6 6 6 4 AAA domain T2SE PF00437.15 CAR25155.1 - 1e-16 60.6 3.8 0.014 14.2 0.0 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_30 PF13604.1 CAR25155.1 - 1.5e-16 60.5 0.0 0.15 11.6 0.1 7.4 7 0 0 7 7 7 4 AAA domain AAA_22 PF13401.1 CAR25155.1 - 9.1e-16 58.1 13.5 0.0095 16.0 0.0 9.1 8 2 1 9 9 7 3 AAA domain UPF0079 PF02367.12 CAR25155.1 - 8.2e-15 54.5 6.2 0.029 13.9 0.1 6.8 7 0 0 7 7 6 3 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 CAR25155.1 - 7e-14 51.3 3.1 0.039 13.7 0.0 6.4 6 0 0 6 6 6 3 Part of AAA domain Zeta_toxin PF06414.7 CAR25155.1 - 1.1e-13 50.7 6.4 0.21 10.6 0.0 8.2 9 0 0 9 9 8 4 Zeta toxin Miro PF08477.8 CAR25155.1 - 2e-12 47.6 3.6 0.58 10.6 0.1 7.3 6 0 0 6 6 6 3 Miro-like protein RNA_helicase PF00910.17 CAR25155.1 - 1.3e-11 44.6 6.1 0.093 12.9 0.0 7.7 7 0 0 7 7 7 2 RNA helicase ABC_tran PF00005.22 CAR25155.1 - 1.9e-11 44.3 23.0 0.0014 18.9 0.0 7.6 7 1 0 7 7 6 3 ABC transporter AAA_25 PF13481.1 CAR25155.1 - 8.8e-11 41.5 0.8 0.03 13.7 0.0 5.0 4 0 0 4 4 4 2 AAA domain MobB PF03205.9 CAR25155.1 - 7.7e-10 38.6 6.6 0.042 13.5 0.0 6.3 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CAR25155.1 - 1e-09 38.0 5.5 0.066 12.7 0.1 6.1 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 CAR25155.1 - 2.6e-09 37.2 4.2 2.6 7.9 0.0 6.9 6 0 0 6 6 6 1 AAA domain DUF258 PF03193.11 CAR25155.1 - 5.9e-09 35.3 10.7 0.12 11.5 0.2 5.5 6 0 0 6 6 5 4 Protein of unknown function, DUF258 NACHT PF05729.7 CAR25155.1 - 1.2e-08 34.8 10.7 0.11 12.1 0.0 5.9 6 0 0 6 6 4 4 NACHT domain Mg_chelatase PF01078.16 CAR25155.1 - 1.8e-08 33.7 0.6 14 4.7 0.0 8.3 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CAR25155.1 - 1.2e-07 32.1 41.6 0.0063 16.8 0.0 9.6 8 2 1 9 9 6 4 AAA domain MMR_HSR1 PF01926.18 CAR25155.1 - 1.2e-07 31.6 1.4 5.5 6.9 0.0 6.7 6 0 0 6 6 6 0 50S ribosome-binding GTPase RuvB_N PF05496.7 CAR25155.1 - 1.5e-07 30.6 0.5 0.26 10.3 0.0 4.9 5 0 0 5 5 5 3 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 CAR25155.1 - 4e-07 29.4 2.7 3.8 7.1 0.0 6.1 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_7 PF12775.2 CAR25155.1 - 6.3e-07 28.7 2.1 1.2 8.1 0.0 4.8 5 0 0 5 5 5 2 P-loop containing dynein motor region D3 ATP-synt_ab PF00006.20 CAR25155.1 - 1.1e-06 28.2 0.0 1 8.8 0.0 3.8 3 1 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 CAR25155.1 - 8.6e-06 25.1 0.6 1.6 7.9 0.0 4.7 4 0 0 4 4 4 1 PhoH-like protein SRP54 PF00448.17 CAR25155.1 - 6.2e-05 22.5 9.8 0.39 10.1 0.1 5.2 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 CAR25155.1 - 0.00096 18.7 9.3 2.3 7.6 0.1 5.6 5 0 0 5 5 5 1 Conserved hypothetical ATP binding protein CPT PF07931.7 CAR25155.1 - 0.0038 16.8 2.2 15 5.1 0.0 5.3 5 1 0 5 5 4 0 Chloramphenicol phosphotransferase-like protein AAA_6 PF12774.2 CAR25155.1 - 0.0065 16.0 0.0 32 3.9 0.0 5.1 5 0 0 5 5 5 0 Hydrolytic ATP binding site of dynein motor region D1 KaiC PF06745.8 CAR25155.1 - 0.0094 15.0 4.8 3.7 6.5 0.1 4.8 5 0 0 5 5 5 0 KaiC FtsK_SpoIIIE PF01580.13 CAR25155.1 - 0.019 14.4 3.3 4.5 6.7 0.0 4.8 5 0 0 5 5 5 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 CAR25155.1 - 0.039 13.6 13.9 1.8 8.2 0.2 5.3 6 0 0 6 6 5 0 NTPase TPP_enzyme_N PF02776.13 CAR25155.1 - 1.2 8.5 0.0 3.8 6.9 0.0 1.8 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ArgK PF03308.11 CAR25155.1 - 9 4.9 7.4 21 3.8 0.0 3.7 5 0 0 5 5 4 0 ArgK protein tRNA_int_endo PF01974.12 CAR25156.1 - 9.2e-23 79.8 0.0 1.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain CDC45 PF02724.9 CAR25158.1 - 2.5e-215 716.2 0.6 2.8e-215 716.0 0.4 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 CAR25158.1 - 0.097 10.5 10.7 0.14 10.0 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.3 CAR25158.1 - 0.11 11.5 4.0 0.17 10.9 2.8 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Daxx PF03344.10 CAR25158.1 - 0.61 8.5 9.8 0.87 7.9 6.8 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 CAR25158.1 - 0.93 9.0 9.8 1.8 8.1 6.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Spt5_N PF11942.3 CAR25158.1 - 0.98 10.0 17.7 0.051 14.2 8.2 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.6 CAR25158.1 - 3.8 5.2 7.2 5 4.8 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 CAR25158.1 - 9.8 4.7 15.0 17 3.9 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Apc9 PF12856.2 CAR25159.1 - 2.5e-17 62.7 0.2 4.8e-17 61.8 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 9 CH PF00307.26 CAR25160.1 - 5.6e-72 238.6 0.1 2.4e-19 69.3 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CAR25160.1 - 5.8e-06 25.8 0.0 0.32 10.6 0.0 4.1 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.1 CAR25160.1 - 1.3e-05 25.2 0.5 0.00025 21.1 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair adh_short PF00106.20 CAR25161.1 - 1.8e-05 24.7 0.0 0.0051 16.7 0.0 2.2 1 1 0 2 2 2 2 short chain dehydrogenase WD40 PF00400.27 CAR25162.1 - 4.9e-16 57.9 22.4 2e-07 30.6 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat RWD PF05773.17 CAR25162.1 - 0.00023 21.0 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 CAR25162.1 - 0.41 10.5 9.2 1.1 9.1 6.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CAR25162.1 - 2.3 8.3 9.6 5.7 7.0 6.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CAR25162.1 - 6.1 6.6 9.7 14 5.5 6.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain EPSP_synthase PF00275.15 CAR25163.1 - 5.3e-139 463.2 0.0 8.2e-139 462.6 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CAR25163.1 - 9.3e-99 329.5 0.0 1.6e-98 328.8 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CAR25163.1 - 2e-65 220.5 0.0 3.7e-65 219.7 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CAR25163.1 - 4.8e-39 133.7 0.1 1e-35 122.9 0.0 3.4 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.6 CAR25163.1 - 1.2e-22 79.7 0.0 4.3e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CAR25163.1 - 4.5e-14 52.6 0.0 2.2e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CAR25163.1 - 8.3e-09 35.1 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CAR25163.1 - 8.1e-06 26.6 0.2 5.2e-05 24.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CAR25163.1 - 0.029 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTP_transf_3 PF12804.2 CAR25163.1 - 0.13 12.3 1.6 0.76 9.8 0.0 2.9 4 0 0 4 4 4 0 MobA-like NTP transferase domain zf-DHHC PF01529.15 CAR25164.1 - 1.5e-25 89.5 11.7 1.5e-25 89.5 8.1 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase Abhydrolase_6 PF12697.2 CAR25167.1 - 6.1e-22 78.6 0.0 1.4e-21 77.4 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR25167.1 - 9.9e-15 54.7 0.0 5.3e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR25167.1 - 6.2e-09 35.7 0.0 1.3e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CAR25167.1 - 0.0043 16.6 0.0 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase DUF915 PF06028.6 CAR25167.1 - 0.02 13.9 0.0 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.9 CAR25167.1 - 0.074 12.3 0.0 1 8.5 0.0 2.5 3 0 0 3 3 3 0 Putative serine esterase (DUF676) DUF2305 PF10230.4 CAR25167.1 - 0.1 11.9 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 CAR25167.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.13 CAR25168.1 - 1.7e-37 128.7 4.9 3.3e-37 127.7 3.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR25168.1 - 5e-10 39.1 11.6 1.1e-09 38.0 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2841 PF11001.3 CAR25169.1 - 4.4e-33 113.8 0.5 6.7e-33 113.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) F-box-like PF12937.2 CAR25170.1 - 7.4e-07 28.7 0.2 1.5e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CAR25170.1 - 0.0066 16.0 0.9 0.016 14.8 0.6 1.6 1 0 0 1 1 1 1 F-box domain HLH PF00010.21 CAR25171.1 - 0.036 13.7 0.5 0.078 12.6 0.3 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 CAR25172.1 - 1.2e-70 237.7 0.7 4.2e-70 235.8 0.5 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25172.1 - 9.5e-40 136.2 0.3 2.1e-38 131.8 0.0 2.1 1 1 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.14 CAR25172.1 - 4.8e-20 70.7 0.0 8.9e-20 69.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 CAR25172.1 - 9.9e-06 24.7 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR25172.1 - 6.2e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR25172.1 - 0.016 14.9 0.0 0.083 12.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.6 CAR25172.1 - 0.094 11.9 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.15 CAR25172.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase YrbL-PhoP_reg PF10707.4 CAR25172.1 - 0.17 11.2 0.9 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PHD PF00628.24 CAR25173.1 - 0.0022 17.6 1.8 0.0022 17.6 1.2 2.4 2 0 0 2 2 2 1 PHD-finger zf-CSL PF05207.8 CAR25173.1 - 0.054 13.0 1.2 0.13 11.7 0.8 1.6 1 0 0 1 1 1 0 CSL zinc finger FMO-like PF00743.14 CAR25175.1 - 3e-26 91.7 0.0 1.3e-15 56.6 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CAR25175.1 - 7.5e-11 41.5 0.0 1.1e-06 27.7 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CAR25175.1 - 4.7e-10 39.8 0.0 1.6e-08 34.8 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR25175.1 - 1.4e-09 37.8 0.0 4.3e-07 29.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CAR25175.1 - 1.3e-06 28.4 0.0 0.00025 20.9 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CAR25175.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CAR25175.1 - 0.049 12.7 0.0 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family F420_oxidored PF03807.12 CAR25175.1 - 0.067 13.6 0.1 0.22 11.9 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 CAR25175.1 - 0.12 12.7 0.0 8.2 6.9 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Nyv1_N PF09426.5 CAR25176.1 - 1.2e-48 164.2 0.1 1.9e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.16 CAR25176.1 - 1.7e-26 91.6 2.8 2.5e-26 91.1 1.9 1.2 1 0 0 1 1 1 1 Synaptobrevin DUF2937 PF11157.3 CAR25176.1 - 0.019 14.3 0.6 0.031 13.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) GLTSCR1 PF15249.1 CAR25176.1 - 0.058 13.5 0.3 0.093 12.8 0.2 1.4 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region DUF2357 PF09823.4 CAR25176.1 - 0.062 12.3 1.0 0.15 11.0 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2357) Fzo_mitofusin PF04799.8 CAR25176.1 - 0.069 12.5 1.8 0.11 11.8 1.3 1.4 1 0 0 1 1 1 0 fzo-like conserved region Oxidored_nitro PF00148.14 CAR25176.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF2077 PF09850.4 CAR25176.1 - 0.14 11.5 1.9 1.6 8.1 0.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) CBFD_NFYB_HMF PF00808.18 CAR25177.1 - 0.00031 20.7 0.2 0.00067 19.6 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TLP-20 PF06088.6 CAR25177.1 - 0.024 14.3 5.9 0.024 14.2 3.5 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RXT2_N PF08595.6 CAR25177.1 - 5.6 6.7 8.3 1.3 8.8 2.6 2.0 2 1 1 3 3 3 0 RXT2-like, N-terminal PBP1_TM PF14812.1 CAR25177.1 - 6.2 7.2 12.2 13 6.1 6.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRM PF02005.11 CAR25178.1 - 1.3e-139 465.2 0.0 1.7e-139 464.9 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CAR25178.1 - 2.9e-06 26.9 0.2 5.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein tRNA_U5-meth_tr PF05958.6 CAR25178.1 - 0.049 12.3 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF917 PF06032.7 CAR25178.1 - 0.17 10.3 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) MFS_1 PF07690.11 CAR25180.1 - 2e-42 145.2 45.5 3.9e-42 144.2 30.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR25180.1 - 7.2e-16 57.8 33.6 5e-14 51.7 6.1 3.6 3 1 1 4 4 4 3 Sugar (and other) transporter Sulfate_transp PF00916.15 CAR25181.1 - 1e-79 267.4 5.0 1e-79 267.4 3.4 1.8 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CAR25181.1 - 2.2e-31 107.3 2.5 2.2e-31 107.3 1.8 2.5 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CAR25181.1 - 3.9e-05 23.0 0.0 7.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CAR25181.1 - 0.0036 17.2 0.1 0.0087 16.0 0.1 1.6 1 0 0 1 1 1 1 STAS domain Serglycin PF04360.7 CAR25181.1 - 1.6 8.4 3.5 12 5.6 0.3 2.4 2 0 0 2 2 2 0 Serglycin Apc4 PF12896.2 CAR25182.1 - 9e-48 162.3 0.1 1.2e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 SUI1 PF01253.17 CAR25183.1 - 1e-16 60.4 0.1 3e-16 58.9 0.1 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.13 CAR25183.1 - 0.0014 18.2 0.0 0.0036 16.9 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Kin17_mid PF10357.4 CAR25183.1 - 0.0023 17.5 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Ribosomal_L1 PF00687.16 CAR25184.1 - 1.3e-28 99.8 0.1 1.5e-28 99.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L34 PF00468.12 CAR25185.1 - 1.5e-19 69.3 5.9 1.5e-19 69.3 4.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L34 Securin PF04856.8 CAR25187.1 - 2.6e-22 79.6 4.1 3.8e-22 79.1 2.9 1.3 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor DnaJ PF00226.26 CAR25188.1 - 2.7e-25 87.8 2.0 4.6e-25 87.1 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CAR25188.1 - 1.9e-22 78.9 0.0 6.3e-19 67.6 0.0 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CAR25188.1 - 2.6e-13 49.7 13.0 5.1e-13 48.8 9.0 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CAR25188.1 - 0.0037 16.9 3.4 0.76 9.4 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 CAR25188.1 - 0.0048 17.2 5.8 0.0091 16.3 4.0 1.5 1 0 0 1 1 1 1 Cytochrome c3 Aminotran_1_2 PF00155.16 CAR25189.1 - 5.5e-41 140.7 0.0 7.8e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CAR25189.1 - 0.0042 16.2 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SseB PF07179.7 CAR25189.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 SseB protein N-terminal domain rve PF00665.21 CAR25190.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Gaa1 PF04114.9 CAR25191.1 - 2.8e-114 382.6 14.7 2.9e-106 356.1 2.7 2.0 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component SMC_N PF02463.14 CAR25193.1 - 1.9e-69 233.2 46.9 5.2e-68 228.5 32.5 3.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAR25193.1 - 4.3e-29 100.9 0.1 5.2e-28 97.4 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CAR25193.1 - 1.6e-11 44.7 2.3 1.6e-06 28.3 0.3 5.0 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 CAR25193.1 - 3.4e-05 23.2 0.0 7.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CAR25193.1 - 1.2 8.2 34.3 0.61 9.2 2.6 5.6 2 2 2 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CAR25193.1 - 5.7 5.2 98.6 0.17 10.2 8.5 6.1 4 2 2 6 6 6 0 AAA domain Actin PF00022.14 CAR25194.1 - 5.4e-58 196.2 0.0 6.7e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Actin FGGY_C PF02782.11 CAR25195.1 - 9.5e-51 172.2 0.5 1.5e-50 171.5 0.4 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CAR25195.1 - 5.5e-25 88.1 0.3 9.4e-24 84.0 0.2 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 CAR25195.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Hexokinase GCR1_C PF12550.3 CAR25196.1 - 2.8e-13 49.5 0.1 4.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Reo_sigmaC PF04582.7 CAR25196.1 - 0.0021 17.2 0.4 0.004 16.3 0.3 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Cep57_CLD_2 PF14197.1 CAR25196.1 - 0.015 15.2 1.8 0.035 14.0 1.3 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 IFP_35_N PF07334.8 CAR25196.1 - 0.025 14.5 0.1 0.13 12.2 0.0 2.3 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_1 PF00170.16 CAR25196.1 - 0.07 13.0 1.4 0.18 11.7 1.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 CAR25196.1 - 0.13 11.7 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Fib_alpha PF08702.5 CAR25196.1 - 0.16 12.0 0.6 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Rax2 PF12768.2 CAR25197.1 - 2.1e-75 253.5 2.5 2.1e-75 253.5 1.8 4.1 5 0 0 5 5 5 2 Cortical protein marker for cell polarity TRAPPC-Trs85 PF12739.2 CAR25198.1 - 6.1e-103 344.6 4.2 8.1e-103 344.2 2.9 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.11 CAR25199.1 - 2.8e-201 669.5 3.8 3.9e-201 669.0 2.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2205 PF10224.4 CAR25200.1 - 6e-10 38.5 4.9 7.1e-10 38.3 3.2 1.3 1 1 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Integrase_DNA PF02920.10 CAR25200.1 - 0.026 13.9 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase DUF4635 PF15466.1 CAR25200.1 - 0.055 12.7 0.6 0.058 12.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Muted PF14942.1 CAR25200.1 - 0.12 12.2 4.2 0.14 12.0 2.9 1.0 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF972 PF06156.8 CAR25200.1 - 0.62 10.4 5.0 0.25 11.6 1.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 CAR25200.1 - 4 6.9 8.5 4.4 6.8 5.9 1.0 1 0 0 1 1 1 0 IncA protein Actin PF00022.14 CAR25202.1 - 1.9e-15 56.2 0.2 1.7e-11 43.1 0.1 2.4 1 1 1 2 2 2 2 Actin Sialidase_penC PF12135.3 CAR25202.1 - 0.34 10.5 1.9 0.78 9.4 1.3 1.5 1 0 0 1 1 1 0 Sialidase enzyme penultimate C terminal domain Serinc PF03348.10 CAR25203.1 - 9.5e-145 482.5 11.8 1.1e-144 482.3 8.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DsbD PF02683.10 CAR25203.1 - 0.017 14.7 7.6 0.69 9.4 0.2 2.9 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Rad51 PF08423.6 CAR25204.1 - 5.3e-124 412.1 0.1 7.7e-124 411.6 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CAR25204.1 - 3.9e-11 42.7 0.0 5.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CAR25204.1 - 1.4e-08 34.2 0.1 1.9e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CAR25204.1 - 3.8e-07 29.4 0.1 1e-06 28.0 0.0 1.8 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.1 CAR25204.1 - 2.1e-05 24.6 0.1 5.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain PAXNEB PF05625.6 CAR25204.1 - 0.00046 19.1 0.0 0.16 10.7 0.0 2.1 2 0 0 2 2 2 2 PAXNEB protein AAA_22 PF13401.1 CAR25204.1 - 0.02 15.0 0.1 0.1 12.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain RNA_pol_A_CTD PF03118.10 CAR25204.1 - 0.038 13.4 0.2 0.078 12.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Peptidase_M24 PF00557.19 CAR25205.1 - 3.2e-08 33.3 0.0 8.1e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Metallopeptidase family M24 E1_dh PF00676.15 CAR25206.1 - 2.3e-119 397.5 0.3 2.9e-119 397.2 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CAR25206.1 - 0.0084 15.0 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 CAR25206.1 - 0.048 14.2 4.6 0.053 14.1 0.1 2.9 2 2 1 3 3 3 0 KRTAP type 7 family Ste5_C PF12194.3 CAR25207.1 - 6.3e-55 185.8 0.1 1.1e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 CAR25207.1 - 0.0002 21.0 7.2 0.0002 21.0 5.0 2.0 2 0 0 2 2 2 1 Ring finger domain PH_10 PF15411.1 CAR25207.1 - 0.028 14.6 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C3HC4_2 PF13923.1 CAR25207.1 - 0.069 13.1 5.4 0.21 11.6 3.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR25207.1 - 0.16 11.6 8.6 0.052 13.2 3.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR25207.1 - 2.5 7.8 6.6 5.1 6.8 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH_4 PF15404.1 CAR25208.1 - 5.7e-75 250.9 0.1 1.6e-74 249.4 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.1 CAR25208.1 - 1e-24 85.7 0.1 1e-24 85.7 0.1 2.5 3 0 0 3 3 3 1 Sporulation protein family 7 PH PF00169.24 CAR25208.1 - 1.2e-08 35.0 4.9 0.00044 20.4 0.4 4.3 3 1 0 3 3 3 2 PH domain PH_9 PF15410.1 CAR25208.1 - 0.04 14.0 0.0 18 5.5 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain COPI_assoc PF08507.5 CAR25209.1 - 4e-35 120.4 2.9 4.5e-35 120.3 2.0 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2838 PF10998.3 CAR25209.1 - 0.35 10.7 5.2 0.49 10.3 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) DUF2892 PF11127.3 CAR25209.1 - 4.3 7.2 9.5 7.3 6.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) 14-3-3 PF00244.15 CAR25210.1 - 7.9e-117 388.4 3.9 9.1e-117 388.2 2.7 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.6 CAR25210.1 - 0.033 14.0 0.1 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF AAA_12 PF13087.1 CAR25211.1 - 5.2e-61 205.5 0.0 1.1e-60 204.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR25211.1 - 1.1e-42 146.2 0.4 1.1e-42 146.2 0.3 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR25211.1 - 6.7e-11 41.7 0.0 1.8e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CAR25211.1 - 1.3e-08 34.6 0.0 1.4e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CAR25211.1 - 1.5e-05 24.6 0.0 0.77 9.2 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CAR25211.1 - 0.0003 20.2 2.7 0.00045 19.6 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 CAR25211.1 - 0.00037 20.3 0.1 0.0015 18.4 0.1 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 CAR25211.1 - 0.00046 20.2 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 CAR25211.1 - 0.0025 17.9 0.0 0.0081 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CAR25211.1 - 0.0049 16.3 0.0 0.0099 15.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1151 PF06625.6 CAR25211.1 - 0.0053 16.4 1.0 0.014 15.1 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) AAA PF00004.24 CAR25211.1 - 0.0066 16.6 0.1 0.026 14.7 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CAR25211.1 - 0.0082 15.3 0.0 0.024 13.8 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein DUF258 PF03193.11 CAR25211.1 - 0.0094 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CAR25211.1 - 0.018 14.7 2.0 0.029 14.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 CAR25211.1 - 0.037 13.9 0.1 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CAR25211.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Methyltransf_11 PF08241.7 CAR25212.1 - 3.4e-15 56.2 0.0 5.4e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR25212.1 - 9.8e-12 45.2 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR25212.1 - 8.2e-11 42.4 0.0 1.3e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR25212.1 - 1.4e-10 41.1 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR25212.1 - 7.3e-10 38.6 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR25212.1 - 3.1e-09 37.0 0.0 4.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR25212.1 - 2.4e-08 33.3 0.0 3.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CAR25212.1 - 5.7e-06 26.3 0.2 1.7e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR25212.1 - 2.3e-05 23.8 0.0 5.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CAR25212.1 - 0.0086 15.2 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 CAR25212.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glutaredoxin PF00462.19 CAR25213.1 - 1.5e-18 66.4 0.3 5e-17 61.6 0.0 2.8 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.15 CAR25213.1 - 8.2e-15 54.3 0.1 1.6e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CAR25213.1 - 3.7e-07 30.1 0.1 8.3e-05 22.6 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CAR25213.1 - 4.7e-07 29.5 0.1 9.2e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CAR25213.1 - 0.00031 20.8 0.3 0.01 16.0 0.0 3.0 2 2 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 CAR25213.1 - 0.0048 16.4 0.1 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 CAR25213.1 - 0.013 15.5 0.0 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like Ribosomal_60s PF00428.14 CAR25213.1 - 0.026 14.9 0.5 0.06 13.7 0.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein HyaE PF07449.6 CAR25213.1 - 0.1 12.4 0.1 0.59 10.0 0.0 2.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Rad17 PF03215.10 CAR25214.1 - 5.6e-82 276.0 1.4 4.5e-62 210.4 0.2 2.4 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CAR25214.1 - 0.00029 20.8 0.1 0.0011 18.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 CAR25214.1 - 0.0042 16.0 0.0 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.7 CAR25214.1 - 0.034 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CAR25214.1 - 0.051 13.7 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 CAR25214.1 - 0.087 12.9 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sec63 PF02889.11 CAR25215.1 - 2.1e-164 546.2 10.4 6.4e-91 304.8 1.5 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CAR25215.1 - 2.3e-44 150.8 0.0 4e-30 104.5 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CAR25215.1 - 9.7e-12 45.0 0.0 1.9e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CAR25215.1 - 2e-09 37.1 0.0 1.9e-06 27.6 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CAR25215.1 - 0.00046 20.3 0.1 0.067 13.3 0.0 3.3 2 0 0 2 2 2 1 AAA domain DUF1227 PF06777.6 CAR25216.1 - 1.6e-57 193.2 0.3 3.9e-57 192.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CAR25216.1 - 6.1e-51 172.2 2.9 1e-50 171.5 2.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CAR25216.1 - 7.6e-45 152.8 0.0 3.6e-44 150.6 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 CAR25216.1 - 0.0012 18.3 0.2 0.47 9.9 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase SNF2_N PF00176.18 CAR25216.1 - 0.0016 17.3 0.1 0.03 13.1 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 CAR25216.1 - 0.0093 15.8 0.0 0.67 9.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CAR25216.1 - 0.011 15.0 0.1 0.32 10.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 CAR25216.1 - 0.018 15.1 1.3 3 7.9 0.0 3.3 3 1 0 3 3 3 0 AAA domain YtxC PF08812.6 CAR25216.1 - 0.056 12.9 1.9 0.34 10.3 0.1 2.6 3 0 0 3 3 3 0 YtxC-like family ADK PF00406.17 CAR25217.1 - 2.9e-40 137.5 0.0 3.5e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CAR25217.1 - 2.9e-14 52.4 0.1 4.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CAR25217.1 - 2.1e-05 24.4 0.0 6e-05 22.9 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR25217.1 - 0.00047 20.4 0.2 0.0024 18.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR25217.1 - 0.02 15.7 0.0 0.035 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CAR25217.1 - 0.025 13.6 0.0 0.039 13.0 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.12 CAR25217.1 - 0.071 12.4 0.1 0.71 9.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase RRM_1 PF00076.17 CAR25218.1 - 1.4e-83 274.4 5.2 4.9e-20 70.9 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR25218.1 - 7.4e-59 195.6 0.3 5.3e-15 55.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR25218.1 - 1e-45 153.3 0.2 2.7e-10 39.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CAR25218.1 - 3.5e-22 77.8 1.6 3.5e-21 74.6 0.0 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CAR25218.1 - 3.5e-06 26.8 8.3 0.16 11.8 0.7 4.9 4 1 1 5 5 5 3 RNA binding motif Nup35_RRM_2 PF14605.1 CAR25218.1 - 0.0031 17.2 0.3 5.4 6.8 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif PNPase PF03726.9 CAR25218.1 - 0.0048 17.1 0.6 0.027 14.7 0.0 2.6 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain GIY-YIG PF01541.19 CAR25218.1 - 0.034 14.5 2.3 1.8 9.0 0.2 2.8 2 0 0 2 2 2 0 GIY-YIG catalytic domain CbiG_mid PF11761.3 CAR25218.1 - 0.049 13.8 0.1 20 5.5 0.0 2.9 2 0 0 2 2 2 0 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 CAR25218.1 - 0.1 12.3 0.5 4.3 7.1 0.0 3.3 4 0 0 4 4 4 0 Limkain b1 OB_RNB PF08206.6 CAR25218.1 - 0.45 10.0 3.2 50 3.4 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain UQ_con PF00179.21 CAR25219.1 - 1.1e-46 157.7 0.0 1.2e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR25219.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CAR25219.1 - 0.012 15.2 0.1 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CAR25219.1 - 0.021 14.6 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain E1-E2_ATPase PF00122.15 CAR25220.1 - 3.6e-15 55.6 1.3 5.2e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CAR25220.1 - 3.6e-13 49.2 0.0 1e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CAR25220.1 - 7.2e-13 49.1 0.0 1.6e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CAR25220.1 - 1.3e-10 42.0 1.9 2.8e-06 27.9 0.9 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CAR25220.1 - 0.0022 17.6 0.2 0.005 16.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PolyA_pol PF01743.15 CAR25222.1 - 6.2e-29 100.7 0.0 1.2e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CAR25222.1 - 1.2e-06 27.9 0.0 5.3e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 CAR25222.1 - 0.0083 15.9 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative PA14_2 PF10528.4 CAR25222.1 - 0.046 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 GLEYA domain JmjC PF02373.17 CAR25223.1 - 4.2e-39 133.3 0.6 4.2e-39 133.3 0.4 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 CAR25223.1 - 3.2e-13 48.9 1.1 7.8e-13 47.7 0.8 1.7 1 0 0 1 1 1 1 jmjN domain zf-H2C2_2 PF13465.1 CAR25223.1 - 9.4e-08 31.9 11.8 6e-07 29.4 5.0 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 CAR25223.1 - 5.4e-07 29.5 16.9 0.0015 18.7 2.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR25223.1 - 2.6e-06 27.3 13.1 0.0013 18.9 0.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CAR25223.1 - 0.0054 16.5 9.7 0.011 15.6 2.3 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 CAR25223.1 - 0.54 10.2 8.1 2.2 8.3 4.3 2.8 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 CAR25223.1 - 2.1 8.4 7.9 0.74 9.9 1.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CAR25223.1 - 3.5 7.8 15.4 0.14 12.3 2.7 3.0 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding MutS_V PF00488.16 CAR25224.1 - 3.9e-75 252.2 0.0 7.4e-75 251.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CAR25224.1 - 1.7e-37 129.2 0.1 2.9e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CAR25224.1 - 2.8e-33 114.3 0.0 5.4e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CAR25224.1 - 4.1e-16 58.9 0.0 8.5e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CAR25224.1 - 1.9e-14 53.9 0.0 4.8e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 CAR25224.1 - 0.056 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNF2_N PF00176.18 CAR25225.1 - 1.8e-75 253.5 0.2 3.6e-75 252.5 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CAR25225.1 - 2.6e-29 101.3 3.4 2.6e-29 101.3 2.3 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CAR25225.1 - 4.3e-23 80.7 1.8 2.4e-13 49.5 0.0 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CAR25225.1 - 3.6e-15 55.5 0.0 1e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 CAR25226.1 - 1.9e-34 118.8 0.0 1.5e-16 60.9 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CAR25226.1 - 9.4e-15 53.9 6.5 2.9e-14 52.3 4.5 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CAR25226.1 - 3.8e-13 50.0 7.6 0.0077 16.2 1.6 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 CAR25226.1 - 6.2e-09 35.4 1.9 0.021 14.0 0.1 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 CAR25226.1 - 1.9e-08 33.5 3.0 1.9e-08 33.5 2.1 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.2 CAR25226.1 - 1.9e-06 27.4 12.9 8.9e-06 25.3 2.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 CAR25226.1 - 7.3e-06 25.2 0.5 2.6 6.9 0.0 4.1 3 1 1 4 4 4 1 AAA ATPase domain AAA PF00004.24 CAR25226.1 - 2.1e-05 24.6 0.0 0.092 12.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CAR25226.1 - 2.4e-05 23.7 0.5 0.13 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CAR25226.1 - 3.7e-05 22.9 2.2 0.16 11.1 0.0 3.0 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAR25226.1 - 5.2e-05 23.3 0.0 0.01 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CAR25226.1 - 9.4e-05 22.5 0.0 0.098 12.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 CAR25226.1 - 0.00019 21.2 12.5 0.00042 20.0 8.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CAR25226.1 - 0.00026 20.7 2.2 0.00026 20.7 1.5 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.1 CAR25226.1 - 0.00066 19.4 1.3 0.00066 19.4 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Miro PF08477.8 CAR25226.1 - 0.001 19.5 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein NB-ARC PF00931.17 CAR25226.1 - 0.0011 17.9 0.0 0.19 10.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Fer4_7 PF12838.2 CAR25226.1 - 0.0013 19.0 1.6 0.0013 19.0 1.1 2.5 1 1 2 3 3 3 1 4Fe-4S dicluster domain AAA_25 PF13481.1 CAR25226.1 - 0.0019 17.6 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CAR25226.1 - 0.003 17.9 0.0 0.21 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CAR25226.1 - 0.0033 17.1 0.7 0.86 9.3 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CAR25226.1 - 0.0035 18.1 0.5 0.92 10.3 0.2 2.9 2 2 0 2 2 2 1 AAA domain NACHT PF05729.7 CAR25226.1 - 0.004 16.8 1.4 0.45 10.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Fer4_16 PF13484.1 CAR25226.1 - 0.0048 17.6 0.1 0.0048 17.6 0.0 2.6 2 1 0 2 2 1 1 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 CAR25226.1 - 0.0058 17.1 4.2 0.0058 17.1 2.9 2.6 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_30 PF13604.1 CAR25226.1 - 0.0071 15.9 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CAR25226.1 - 0.0091 16.3 0.7 1 9.6 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 CAR25226.1 - 0.0095 15.6 1.1 0.08 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) VirE PF05272.6 CAR25226.1 - 0.0096 15.4 0.0 0.95 8.8 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E SRP54 PF00448.17 CAR25226.1 - 0.011 15.1 2.0 0.85 9.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_9 PF13187.1 CAR25226.1 - 0.011 15.9 12.7 0.037 14.2 8.8 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain RNA_helicase PF00910.17 CAR25226.1 - 0.013 15.6 0.0 4.1 7.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CAR25226.1 - 0.015 15.2 0.0 2.2 8.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 CAR25226.1 - 0.019 14.9 0.0 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CAR25226.1 - 0.02 14.8 0.1 11 6.0 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 CAR25226.1 - 0.028 14.0 0.2 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Fer4_4 PF12800.2 CAR25226.1 - 0.028 14.7 2.5 0.028 14.7 1.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_14 PF13173.1 CAR25226.1 - 0.038 13.8 0.0 14 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 CAR25226.1 - 0.04 13.9 7.5 0.12 12.4 5.3 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain T2SE PF00437.15 CAR25226.1 - 0.06 12.2 0.0 0.73 8.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Rad17 PF03215.10 CAR25226.1 - 0.1 11.2 0.0 0.98 8.0 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF2603 PF10788.4 CAR25226.1 - 0.11 12.2 0.0 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) MMR_HSR1 PF01926.18 CAR25226.1 - 0.17 11.8 0.2 29 4.6 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 CAR25226.1 - 0.96 8.9 2.6 1.8 8.0 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_15 PF13459.1 CAR25226.1 - 4 8.0 8.9 0.097 13.2 0.8 2.4 2 0 0 2 2 1 0 4Fe-4S single cluster domain ChaC PF04752.7 CAR25227.1 - 4.2e-52 176.6 0.0 5.3e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Rad4 PF03835.10 CAR25228.1 - 3.8e-35 120.4 3.4 9.5e-35 119.1 2.3 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 CAR25228.1 - 3.2e-26 90.8 0.2 5.3e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 CAR25228.1 - 3.2e-18 64.9 0.0 7.7e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CAR25228.1 - 5.2e-09 36.2 1.0 1.5e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CAR25228.1 - 1.5e-08 34.8 0.0 6.5e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF1411 PF07199.6 CAR25228.1 - 0.055 12.9 0.3 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) SPT2 PF08243.6 CAR25229.1 - 1.7e-27 95.9 23.5 1.7e-27 95.9 16.3 2.4 2 0 0 2 2 2 1 SPT2 chromatin protein Ndc1_Nup PF09531.5 CAR25229.1 - 2.7 6.3 6.6 3.2 6.0 4.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.14 CAR25230.1 - 3e-09 37.0 0.3 3e-09 37.0 0.2 3.5 3 1 1 4 4 4 2 SPX domain MRP-S26 PF14943.1 CAR25230.1 - 0.13 11.7 0.3 0.29 10.6 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Slu7 PF11708.3 CAR25231.1 - 7.8e-42 143.6 13.8 3.1e-41 141.7 9.6 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.18 CAR25231.1 - 0.00034 20.3 0.2 0.00056 19.7 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle TTSSLRR PF12468.3 CAR25231.1 - 0.58 9.7 2.7 1.3 8.5 0.3 2.3 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Nop52 PF05997.7 CAR25232.1 - 2.6e-70 236.2 3.4 3.2e-70 235.9 2.4 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 SecE PF00584.15 CAR25233.1 - 1.8e-10 40.2 0.1 1.9e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex EAL PF00563.15 CAR25233.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 EAL domain Coiled-coil_56 PF09813.4 CAR25233.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 CBFD_NFYB_HMF PF00808.18 CAR25234.1 - 4.5e-10 39.4 0.1 7.1e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CLIP PF12032.3 CAR25234.1 - 0.084 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases SSF PF00474.12 CAR25235.1 - 1.8e-06 26.8 31.9 7.1e-06 24.9 22.1 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family DUF846 PF05832.7 CAR25237.1 - 5e-48 162.4 3.7 6e-48 162.1 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF3329 PF11808.3 CAR25237.1 - 7.9 6.6 7.0 4 7.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Methyltransf_8 PF05148.10 CAR25238.1 - 1.1e-65 221.3 1.9 1e-63 214.9 0.2 2.5 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CAR25238.1 - 2.3e-07 31.2 2.4 9e-07 29.3 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR25238.1 - 9.9e-05 21.9 3.1 0.00016 21.3 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CAR25238.1 - 0.023 14.0 0.0 1.1 8.5 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 CAR25238.1 - 0.033 14.5 0.3 0.27 11.5 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 CAR25238.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.5 3 1 0 3 3 3 0 Methyltransferase domain AvrE PF11725.3 CAR25238.1 - 1.4 5.7 14.4 2 5.3 10.0 1.1 1 0 0 1 1 1 0 Pathogenicity factor ATP_sub_h PF10775.4 CAR25239.1 - 1e-25 89.1 0.3 1.5e-25 88.6 0.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ADIP PF11559.3 CAR25240.1 - 0.00015 21.7 1.4 0.00078 19.3 0.0 2.5 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding MIP-T3 PF10243.4 CAR25240.1 - 0.18 10.2 3.7 0.21 9.9 2.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ras PF00071.17 CAR25241.1 - 1.3e-50 170.9 0.0 1.5e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR25241.1 - 4e-17 62.7 0.0 8.6e-17 61.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR25241.1 - 2e-11 43.4 0.0 2.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CAR25241.1 - 0.00068 19.7 0.1 0.0056 16.8 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CAR25241.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region KaiC PF06745.8 CAR25241.1 - 0.019 14.0 0.2 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.7 CAR25241.1 - 0.027 13.7 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.5 CAR25241.1 - 0.036 13.2 0.0 0.06 12.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CAR25241.1 - 0.05 12.3 2.8 1.2 7.7 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 CAR25241.1 - 0.052 13.6 0.2 0.18 11.9 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 CAR25241.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 CAR25242.1 - 1.9e-06 27.4 0.1 0.0047 16.5 0.0 2.6 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 CAR25242.1 - 5.5e-06 25.7 1.8 0.005 16.4 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR25242.1 - 1.1e-05 24.9 0.8 0.00064 19.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR25242.1 - 6.2e-05 23.2 1.3 0.00019 21.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CAR25242.1 - 0.0037 17.0 1.0 0.01 15.6 0.1 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 CAR25242.1 - 0.0042 17.6 0.5 0.038 14.6 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR25242.1 - 0.0068 16.1 0.2 0.15 11.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CAR25242.1 - 0.013 16.1 0.0 0.11 13.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Med29 PF11568.3 CAR25242.1 - 0.034 14.1 0.5 0.056 13.4 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 29 Syntaxin_2 PF14523.1 CAR25242.1 - 0.047 13.7 0.8 0.088 12.8 0.6 1.5 1 0 0 1 1 1 0 Syntaxin-like protein HD_3 PF13023.1 CAR25242.1 - 0.066 12.9 1.1 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 HD domain Xol-1_N PF09108.5 CAR25242.1 - 0.074 12.7 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal DUF3502 PF12010.3 CAR25242.1 - 0.089 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) DUF1525 PF07511.6 CAR25242.1 - 0.15 12.0 1.3 4.3 7.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) DUF3861 PF12977.2 CAR25242.1 - 0.2 11.8 2.3 0.34 11.0 1.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) Syntaxin PF00804.20 CAR25242.1 - 1.3 9.2 5.2 4.1 7.6 2.5 2.3 1 1 1 2 2 2 0 Syntaxin IF-2B PF01008.12 CAR25243.1 - 1.4e-81 273.5 0.1 2.1e-81 273.0 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family TetR_C_9 PF14514.1 CAR25243.1 - 0.035 13.9 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal NAD_binding_10 PF13460.1 CAR25244.1 - 1.1e-12 48.3 0.0 9.3e-11 42.0 0.0 2.4 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CAR25244.1 - 2.6e-08 33.6 0.0 4.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CAR25244.1 - 9.1e-07 27.8 0.0 5.7e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CAR25244.1 - 1.7e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CAR25244.1 - 5.5e-05 22.2 0.0 0.25 10.2 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CAR25244.1 - 0.0013 17.6 0.0 0.0067 15.3 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 CAR25244.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 CAR25244.1 - 0.055 12.7 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family GTP_EFTU PF00009.22 CAR25245.1 - 5e-49 166.2 0.0 1.1e-48 165.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CAR25245.1 - 5.2e-39 132.4 9.1 1.1e-38 131.4 6.3 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CAR25245.1 - 7.1e-19 67.4 0.0 1.9e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR25245.1 - 5.2e-06 26.4 2.8 9.9e-06 25.5 1.2 2.1 2 1 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.17 CAR25245.1 - 1.3e-05 24.6 0.5 6.3e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 CAR25245.1 - 2.5e-05 24.2 0.0 6.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 CAR25245.1 - 0.0093 15.7 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 CAR25245.1 - 0.0094 15.1 0.0 0.024 13.8 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Methyltransf_FA PF12248.3 CAR25245.1 - 0.091 12.7 0.4 0.89 9.6 0.2 2.3 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase Hus1 PF04005.7 CAR25246.1 - 6.8e-20 71.1 0.0 2.2e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 Hus1-like protein Aminotran_5 PF00266.14 CAR25247.1 - 8.4e-33 113.6 0.0 1.1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_S30 PF04758.9 CAR25248.1 - 7.3e-30 102.5 5.1 8.5e-30 102.2 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GCIP PF13324.1 CAR25249.1 - 2.4e-07 30.2 0.0 6.3e-07 28.8 0.0 1.7 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting Exo70 PF03081.10 CAR25249.1 - 0.026 13.3 0.1 0.069 11.9 0.2 1.6 2 0 0 2 2 2 0 Exo70 exocyst complex subunit GAT PF03127.9 CAR25249.1 - 0.11 12.4 0.3 2.4 8.2 0.1 2.6 1 1 1 2 2 2 0 GAT domain DASH_Dam1 PF08653.5 CAR25249.1 - 2 8.2 3.9 20 5.0 0.0 4.0 5 0 0 5 5 5 0 DASH complex subunit Dam1 WH1 PF00568.18 CAR25250.1 - 4.9e-32 109.9 0.0 6.8e-32 109.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 CAR25250.1 - 7e-05 22.2 1.2 0.00014 21.3 0.8 1.5 1 0 0 1 1 1 1 WH2 motif Methyltransf_16 PF10294.4 CAR25252.1 - 4.3e-12 45.8 0.0 6.8e-12 45.1 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CAR25252.1 - 0.00062 19.5 0.0 0.00088 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ECH PF00378.15 CAR25253.1 - 2.1e-12 46.6 0.0 4.5e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1640 PF07798.6 CAR25254.1 - 7.3e-05 22.8 0.7 0.0001 22.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) RF-1 PF00472.15 CAR25255.1 - 2.4e-20 72.4 3.7 3.6e-20 71.8 2.6 1.3 1 0 0 1 1 1 1 RF-1 domain Fungal_trans PF04082.13 CAR25256.1 - 8.1e-19 67.4 6.1 2e-18 66.2 4.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR25256.1 - 0.00013 21.7 11.0 0.00013 21.7 7.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSF73-100_C PF11718.3 CAR25257.1 - 1.5e-60 204.2 2.1 2.4e-60 203.5 1.4 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CAR25257.1 - 8.2e-32 109.7 0.0 2.3e-31 108.3 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CAR25257.1 - 1.3e-16 60.8 0.7 2.2e-16 60.0 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CAR25257.1 - 4.9e-13 49.0 0.9 7.9e-12 45.1 0.5 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CAR25257.1 - 1.1e-10 41.0 0.0 2.6e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CAR25257.1 - 7.8e-06 25.6 0.1 2.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DEAD PF00270.24 CAR25258.1 - 2.8e-39 134.3 1.5 6.1e-39 133.2 1.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR25258.1 - 2.2e-22 78.6 1.6 7.9e-11 41.6 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 CAR25258.1 - 3.3e-05 23.8 0.2 0.00031 20.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAR25258.1 - 0.063 13.4 0.1 0.25 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain DnaI_N PF07319.6 CAR25258.1 - 0.68 10.2 4.6 5.1 7.4 0.3 3.3 2 2 0 2 2 2 0 Primosomal protein DnaI N-terminus LSM PF01423.17 CAR25259.1 - 3.2e-17 61.8 1.0 4.3e-17 61.4 0.7 1.1 1 0 0 1 1 1 1 LSM domain MCM PF00493.18 CAR25260.1 - 1.5e-142 474.2 0.1 2e-142 473.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR25260.1 - 1.8e-18 67.1 0.0 6.3e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR25260.1 - 3.3e-06 26.3 0.0 0.00055 19.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAR25260.1 - 4.9e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAR25260.1 - 0.00025 20.6 0.0 0.0029 17.2 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAR25260.1 - 0.024 14.1 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 CAR25260.1 - 0.1 13.0 0.2 0.46 10.9 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CBM_21 PF03370.8 CAR25262.1 - 8.2e-28 96.6 2.7 1.5e-27 95.8 1.9 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CAR25262.1 - 0.15 12.1 4.4 5.6 7.1 2.1 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Myosin_tail_1 PF01576.14 CAR25263.1 - 0.21 9.2 56.7 27 2.2 33.1 3.0 1 1 0 1 1 1 0 Myosin tail Reo_sigmaC PF04582.7 CAR25263.1 - 0.5 9.4 12.4 0.62 9.1 0.6 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 CAR25263.1 - 1.2 6.3 48.7 0.013 12.8 21.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1795 PF08786.6 CAR25263.1 - 4.4 7.1 12.0 1.1 9.1 0.4 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1795) Cnd1 PF12717.2 CAR25264.1 - 1.1e-53 181.7 12.6 1.1e-50 171.9 0.2 4.4 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CAR25264.1 - 6.4e-50 169.1 0.1 2.7e-49 167.0 0.0 2.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 CAR25264.1 - 3e-12 46.6 0.1 3.8e-05 23.8 0.1 4.3 2 1 2 4 4 4 4 HEAT repeats HEAT PF02985.17 CAR25264.1 - 8.3e-11 41.0 5.1 0.05 13.7 0.1 5.8 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.1 CAR25264.1 - 1.2e-07 32.0 0.3 0.73 10.4 0.0 5.1 4 0 0 4 4 4 2 HEAT-like repeat Cnd3 PF12719.2 CAR25264.1 - 1.3e-05 24.3 4.8 7.3e-05 21.8 0.1 3.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Vpu PF00558.14 CAR25264.1 - 0.12 11.9 7.8 7.9 6.1 2.0 4.3 4 0 0 4 4 4 0 Vpu protein Ferrochelatase PF00762.14 CAR25265.1 - 6.2e-91 304.6 0.0 7.1e-91 304.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MBOAT PF03062.14 CAR25266.1 - 1.7e-54 185.1 14.6 3.6e-54 184.0 10.1 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family TBD PF12845.2 CAR25266.1 - 0.11 12.0 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 TBD domain Med4 PF10018.4 CAR25267.1 - 5.4e-36 123.7 4.0 7.2e-36 123.3 2.7 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Aft1_HRA PF11786.3 CAR25267.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Aft1 HRA domain DUF4187 PF13821.1 CAR25268.1 - 2.7e-18 65.2 0.4 5.4e-18 64.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CAR25268.1 - 2.6e-07 30.3 1.9 4.7e-07 29.4 1.3 1.4 1 0 0 1 1 1 1 G-patch domain Cu_amine_oxidN2 PF02727.11 CAR25268.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain zf-C2H2_jaz PF12171.3 CAR25268.1 - 0.05 13.7 1.1 0.097 12.8 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CAR25268.1 - 0.18 11.7 0.6 0.3 11.0 0.4 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger G-patch_2 PF12656.2 CAR25268.1 - 0.41 10.5 4.5 0.37 10.6 0.3 2.5 2 0 0 2 2 2 0 DExH-box splicing factor binding site DcpS PF05652.7 CAR25269.1 - 9.9e-38 128.9 0.0 1.5e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CAR25269.1 - 5.2e-33 113.7 0.0 1.1e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Longin PF13774.1 CAR25270.1 - 3.1e-20 71.5 0.1 4.7e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CAR25270.1 - 1.3e-16 59.9 0.2 2.4e-16 59.1 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 CAR25270.1 - 0.0079 15.9 1.6 0.0079 15.9 1.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) HAUS-augmin3 PF14932.1 CAR25270.1 - 0.13 11.4 1.5 0.21 10.7 1.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Pyrid_oxidase_2 PF13883.1 CAR25271.1 - 5.7e-40 136.8 0.6 1.8e-39 135.2 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Prp19_bind PF06991.6 CAR25272.1 - 1.6e-07 30.8 10.0 1.6e-07 30.8 7.0 1.7 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain RibD_C PF01872.12 CAR25273.1 - 3e-33 115.1 0.0 3.4e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain RNA_pol_Rpb5_C PF01191.14 CAR25274.1 - 6.7e-34 115.3 0.9 1.3e-33 114.4 0.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CAR25274.1 - 9.7e-34 115.6 0.6 1.8e-33 114.8 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CAR25274.1 - 0.068 12.9 0.0 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease Sof1 PF04158.9 CAR25274.1 - 0.092 12.7 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Sof1-like domain SH3_2 PF07653.12 CAR25274.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain DUF3337 PF11816.3 CAR25275.1 - 6.7e-56 190.0 1.9 1.4e-49 169.2 0.3 3.4 2 2 1 3 3 3 3 Domain of unknown function (DUF3337) WD40 PF00400.27 CAR25275.1 - 2.7e-05 23.8 0.4 1 9.3 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat CENP-S PF15630.1 CAR25276.1 - 3.4e-24 84.8 0.0 4.9e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CAR25276.1 - 0.00021 20.6 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CAR25276.1 - 0.0022 17.7 0.0 0.0043 16.8 0.0 1.5 1 1 1 2 2 2 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CAR25276.1 - 0.026 14.6 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PCP_red PF08369.5 CAR25276.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Ribosomal_S9 PF00380.14 CAR25277.1 - 2.6e-38 130.9 0.5 4.2e-38 130.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Pox_VLTF3 PF04947.9 CAR25277.1 - 0.065 12.7 0.2 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like ADH_zinc_N PF00107.21 CAR25278.1 - 3.6e-31 107.3 0.5 5.4e-31 106.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR25278.1 - 8.1e-31 106.0 0.6 2e-30 104.7 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CAR25278.1 - 0.00014 22.7 0.1 0.00035 21.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase YbjQ_1 PF01906.12 CAR25278.1 - 0.064 13.6 1.1 0.16 12.3 0.8 1.7 1 0 0 1 1 1 0 Putative heavy-metal-binding Gp_dh_C PF02800.15 CAR25280.1 - 1.2e-73 245.8 0.1 1.7e-73 245.2 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CAR25280.1 - 2.4e-59 199.6 0.1 4.4e-59 198.7 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 CAR25280.1 - 0.059 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CAR25280.1 - 0.097 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF221 PF02714.10 CAR25281.1 - 7.8e-104 347.0 15.9 7.8e-104 347.0 11.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CAR25281.1 - 3.8e-41 140.2 3.5 7.8e-41 139.2 1.2 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CAR25281.1 - 2.5e-27 94.5 0.4 6.4e-27 93.2 0.1 1.9 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 CAR25281.1 - 2.4e-17 63.2 0.9 5.6e-17 62.0 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) YopR_core PF09025.5 CAR25281.1 - 0.076 13.0 0.2 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 YopR Core YwiC PF14256.1 CAR25281.1 - 0.085 12.9 18.4 3.2 7.8 0.0 5.1 4 1 1 5 5 5 0 YwiC-like protein ZZ PF00569.12 CAR25282.1 - 4.1e-06 26.2 0.7 4.1e-06 26.2 0.5 2.8 3 0 0 3 3 3 1 Zinc finger, ZZ type ATG19_autophagy PF12744.2 CAR25283.1 - 2.6e-92 308.3 0.4 3.9e-92 307.7 0.3 1.3 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding ZZ PF00569.12 CAR25283.1 - 4.9e-07 29.1 8.9 1.2e-06 27.9 2.4 2.5 1 1 1 2 2 2 2 Zinc finger, ZZ type eRF1_2 PF03464.10 CAR25284.1 - 7.8e-46 155.6 0.1 1.3e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CAR25284.1 - 7.9e-40 135.6 0.2 1.5e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CAR25284.1 - 1.6e-28 98.8 0.1 2.8e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 CAR25284.1 - 0.024 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DEAD PF00270.24 CAR25285.1 - 3e-36 124.4 0.0 7.7e-36 123.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR25285.1 - 2e-23 82.0 0.1 5.7e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3321 PF11968.3 CAR25286.1 - 6.1e-80 267.9 0.1 7.8e-80 267.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CAR25286.1 - 0.00067 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RasGAP PF00616.14 CAR25287.1 - 6.8e-38 130.3 2.0 2.3e-37 128.5 0.1 3.0 4 0 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase Drf_DAD PF06345.6 CAR25287.1 - 0.78 9.6 1.3 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 DRF Autoregulatory Domain Pneumo_att_G PF05539.6 CAR25287.1 - 2.9 7.1 8.3 5.7 6.2 5.8 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RNase_T PF00929.19 CAR25288.1 - 2.1e-25 89.9 0.0 4.2e-25 88.9 0.0 1.5 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CAR25288.1 - 0.009 15.5 0.0 0.028 13.9 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease SIN1 PF05422.7 CAR25289.1 - 1.3e-28 99.8 0.0 9.4e-28 97.0 0.0 2.2 1 1 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 CAR25289.1 - 0.00011 21.9 0.0 0.00038 20.3 0.0 2.0 2 0 0 2 2 2 1 GLUT4 regulating protein TUG Peptidase_S10 PF00450.17 CAR25290.1 - 2.5e-129 432.1 0.3 3e-129 431.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CAR25290.1 - 0.0067 16.3 0.0 0.045 13.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2611 PF11022.3 CAR25291.1 - 3.9e-27 94.1 0.1 4.3e-27 94.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Brix PF04427.13 CAR25292.1 - 7.5e-41 139.8 0.2 9.6e-41 139.5 0.1 1.1 1 0 0 1 1 1 1 Brix domain NatB_MDM20 PF09797.4 CAR25293.1 - 3.9e-63 213.3 8.7 6.8e-63 212.5 6.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 CAR25293.1 - 0.01 16.1 0.2 3.1 8.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAR25293.1 - 0.033 14.8 0.0 17 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SinI PF08671.5 CAR25293.1 - 0.13 11.6 0.0 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Anti-repressor SinI Mannosyl_trans3 PF11051.3 CAR25294.1 - 1.2e-88 296.9 0.0 1.9e-88 296.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glutaredoxin PF00462.19 CAR25295.1 - 4.7e-13 48.9 0.0 8.7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin zf-Apc11 PF12861.2 CAR25296.1 - 1.9e-41 139.8 4.8 2.8e-41 139.2 3.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CAR25296.1 - 3.2e-30 104.0 3.9 4.1e-30 103.7 2.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CAR25296.1 - 1.1e-07 31.6 14.3 4.7e-07 29.5 9.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR25296.1 - 0.00013 21.5 11.1 0.00043 19.9 7.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 CAR25296.1 - 0.0015 18.1 12.8 0.0018 17.8 1.4 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CAR25296.1 - 0.0017 18.3 11.8 0.0059 16.6 8.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CAR25296.1 - 0.0035 17.1 2.8 0.0035 17.1 2.0 1.9 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CAR25296.1 - 0.0077 15.8 11.8 0.13 12.0 8.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CAR25296.1 - 0.02 14.5 14.6 0.098 12.3 10.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TerY-C PF15616.1 CAR25296.1 - 0.045 13.6 4.2 0.057 13.3 2.9 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING-like PF08746.6 CAR25296.1 - 0.17 11.9 10.0 0.69 9.9 6.9 2.0 1 1 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 CAR25296.1 - 0.71 9.8 17.7 19 5.2 12.3 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 CAR25296.1 - 1.2 9.3 9.3 4.8 7.4 6.4 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CAR25296.1 - 2.3 8.2 8.9 7.5 6.6 6.2 1.8 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-HIT PF04438.11 CAR25296.1 - 2.6 7.7 8.5 1 9.0 2.8 2.2 2 0 0 2 2 2 0 HIT zinc finger RINGv PF12906.2 CAR25296.1 - 2.8 8.0 8.9 8.1 6.5 6.2 1.9 1 1 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 CAR25296.1 - 5.3 6.8 7.7 4.3 7.1 3.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger RCR PF12273.3 CAR25297.1 - 1.4e-30 106.4 7.9 3.9e-30 105.0 5.4 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 CAR25297.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) ATG27 PF09451.5 CAR25297.1 - 0.054 12.7 0.6 0.073 12.2 0.4 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF3328 PF11807.3 CAR25297.1 - 0.14 11.8 2.9 0.6 9.7 2.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Aldedh PF00171.17 CAR25298.1 - 6.8e-158 525.7 0.5 7.8e-158 525.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3194 PF11419.3 CAR25298.1 - 0.022 14.9 0.0 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3194) DUF1487 PF07368.6 CAR25298.1 - 0.17 11.1 0.1 0.42 9.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Rad51 PF08423.6 CAR25299.1 - 7.7e-28 97.0 0.0 1e-26 93.3 0.0 2.1 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CAR25299.1 - 2.7e-11 43.2 0.0 4.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CAR25299.1 - 0.00073 18.7 0.0 0.0016 17.5 0.0 1.6 1 1 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 CAR25299.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase CobU PF02283.11 CAR25299.1 - 0.053 12.9 0.1 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RecA PF00154.16 CAR25299.1 - 0.079 12.0 0.5 0.32 10.0 0.3 1.9 1 1 0 1 1 1 0 recA bacterial DNA recombination protein Maf1 PF09174.5 CAR25300.1 - 5.1e-51 173.0 3.3 4.1e-49 166.8 1.2 2.4 1 1 0 2 2 2 2 Maf1 regulator Sel1 PF08238.7 CAR25301.1 - 2.3e-09 37.5 3.8 0.0028 18.2 0.0 3.4 3 0 0 3 3 3 3 Sel1 repeat Tcp11 PF05794.8 CAR25302.1 - 1.2e-125 419.6 3.6 1.2e-125 419.6 2.5 2.2 2 1 1 3 3 3 1 T-complex protein 11 Histone PF00125.19 CAR25303.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25303.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CAR25303.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CAR25303.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CAR25303.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CAR25303.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CAR25303.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CAR25303.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CAR25304.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CAR25304.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CAR25304.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CAR25304.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PRAI PF00697.17 CAR25305.1 - 9.1e-54 182.0 0.0 1.3e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase FMN_dh PF01070.13 CAR25305.1 - 0.089 11.6 0.1 5.6 5.7 0.0 2.3 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Pyrophosphatase PF00719.14 CAR25306.1 - 6.4e-53 178.3 0.1 8.3e-53 178.0 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase RCR PF12273.3 CAR25307.1 - 5.6e-31 107.7 2.4 8.2e-31 107.2 1.2 1.6 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Mannosyl_trans2 PF04188.8 CAR25308.1 - 2.6e-85 286.9 34.1 1.9e-83 280.8 23.7 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) polyprenyl_synt PF00348.12 CAR25309.1 - 1.5e-52 178.0 0.0 9e-25 86.9 0.0 3.0 3 0 0 3 3 3 3 Polyprenyl synthetase Prenyltransf PF01255.14 CAR25310.1 - 1.8e-80 269.2 0.0 2.2e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase ThiG PF05690.9 CAR25310.1 - 0.025 13.6 0.1 0.052 12.6 0.0 1.5 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ran_BP1 PF00638.13 CAR25311.1 - 9.3e-54 180.6 0.8 1.5e-53 179.9 0.6 1.3 1 0 0 1 1 1 1 RanBP1 domain VID27 PF08553.5 CAR25311.1 - 1.1e-05 23.9 1.9 1.3e-05 23.7 1.3 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein WH1 PF00568.18 CAR25311.1 - 0.00011 21.8 1.0 0.0015 18.2 0.7 2.1 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 CAR25311.1 - 0.73 9.3 4.5 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) DUF809 PF05663.6 CAR25311.1 - 6.7 6.6 10.7 9.5 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Trehalase PF01204.13 CAR25312.1 - 6.6e-185 615.5 0.2 7.9e-185 615.3 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CAR25312.1 - 4.2e-16 57.9 1.5 7.2e-16 57.2 1.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF77 PF01910.12 CAR25313.1 - 1.6e-29 101.4 0.1 1.8e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 DUF1341 PF07071.6 CAR25313.1 - 0.043 13.3 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) Histone PF00125.19 CAR25314.1 - 8.2e-22 77.1 0.2 1.2e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25314.1 - 7.6e-06 25.9 0.1 7.6e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CAR25314.1 - 0.0016 18.6 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 CAR25314.1 - 0.016 13.8 3.2 0.02 13.6 2.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Histone PF00125.19 CAR25315.1 - 1.9e-25 88.7 0.0 2.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR25315.1 - 1.7e-05 24.7 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF155 PF02582.9 CAR25316.1 - 3.5e-60 202.8 1.2 5.5e-60 202.2 0.8 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 CAR25316.1 - 0.057 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 HMG_box PF00505.14 CAR25317.1 - 2.4e-15 56.5 0.8 5.6e-15 55.3 0.5 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CAR25317.1 - 2.9e-14 53.1 0.9 5e-14 52.4 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain DUF4407 PF14362.1 CAR25317.1 - 0.24 10.3 3.1 0.3 10.0 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3987 PF13148.1 CAR25317.1 - 1.2 7.6 8.5 0.33 9.4 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) YqzL PF14006.1 CAR25317.1 - 4.4 7.5 0.0 4.4 7.5 0.0 2.6 2 1 0 2 2 2 0 YqzL-like protein DRIM PF07539.7 CAR25318.1 - 7.8e-45 151.7 0.5 7.8e-45 151.7 0.3 3.0 4 0 0 4 4 4 1 Down-regulated in metastasis Med13_N PF11597.3 CAR25318.1 - 0.068 11.8 0.0 0.15 10.6 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Rad21_Rec8_N PF04825.8 CAR25319.1 - 6.5e-25 87.2 0.1 1.2e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CAR25319.1 - 8.7e-11 40.8 0.0 2e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Myb_DNA-bind_5 PF13873.1 CAR25319.1 - 0.028 14.3 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ScpA_ScpB PF02616.9 CAR25319.1 - 0.031 13.8 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 ScpA/B protein ATP-synt_DE_N PF02823.11 CAR25320.1 - 1.4e-18 66.4 0.1 2.4e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Med2 PF11214.3 CAR25321.1 - 1.1e-29 102.5 5.5 1.8e-29 101.8 3.8 1.3 1 0 0 1 1 1 1 Mediator complex subunit 2 Med29 PF11568.3 CAR25321.1 - 0.0003 20.8 2.5 0.00051 20.1 1.8 1.4 1 0 0 1 1 1 1 Mediator complex subunit 29 DUF445 PF04286.7 CAR25321.1 - 0.028 13.9 0.7 0.034 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ANAPC15 PF15243.1 CAR25321.1 - 0.057 13.5 2.5 0.062 13.3 0.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF3121 PF11319.3 CAR25321.1 - 0.52 9.7 3.7 1.2 8.6 0.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3121) PP2C PF00481.16 CAR25322.1 - 5.3e-72 242.2 0.3 8e-72 241.6 0.2 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C Trp_oprn_chp PF09534.5 CAR25322.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AAA PF00004.24 CAR25323.1 - 8.5e-41 139.2 0.0 1.4e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR25323.1 - 2.3e-06 27.7 0.1 0.00013 22.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CAR25323.1 - 5.9e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CAR25323.1 - 2.4e-05 23.4 0.0 4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CAR25323.1 - 3.7e-05 23.4 0.0 0.00016 21.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR25323.1 - 0.00025 21.0 0.0 0.00083 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CAR25323.1 - 0.0015 17.6 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CAR25323.1 - 0.0015 18.4 0.3 0.0039 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CAR25323.1 - 0.0017 18.2 0.0 0.0048 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR25323.1 - 0.006 17.3 0.9 0.013 16.3 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CAR25323.1 - 0.0061 16.8 0.1 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR25323.1 - 0.0072 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CAR25323.1 - 0.0073 16.0 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CAR25323.1 - 0.0074 15.7 1.2 0.21 10.9 0.3 2.5 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAR25323.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 CAR25323.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CAR25323.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CAR25323.1 - 0.015 14.0 0.0 0.029 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 CAR25323.1 - 0.016 14.0 0.0 0.04 12.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 CAR25323.1 - 0.037 14.2 0.0 0.092 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 CAR25323.1 - 0.05 13.3 0.1 0.43 10.2 0.0 2.5 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 CAR25323.1 - 0.05 12.7 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CAR25323.1 - 0.051 12.6 0.0 0.4 9.7 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.1 CAR25323.1 - 0.053 13.1 0.2 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CAR25323.1 - 0.058 12.6 0.2 0.2 10.8 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.17 CAR25323.1 - 0.073 12.9 0.0 0.43 10.4 0.0 2.3 3 0 0 3 3 3 0 Shikimate kinase NACHT PF05729.7 CAR25323.1 - 0.12 12.0 0.2 0.35 10.4 0.1 1.8 2 0 0 2 2 2 0 NACHT domain Sulfate_transp PF00916.15 CAR25324.1 - 1.1e-56 191.8 8.2 2.2e-56 190.9 5.7 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CAR25324.1 - 3e-27 94.1 3.0 3e-27 94.1 2.1 2.5 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CAR25324.1 - 2e-15 56.2 0.0 5e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CAR25324.1 - 0.023 14.7 0.0 0.068 13.2 0.0 1.9 1 1 0 1 1 1 0 STAS domain CAAD PF14159.1 CAR25324.1 - 5.6 6.6 6.3 2.9 7.6 0.3 2.8 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ETF PF01012.16 CAR25325.1 - 1e-33 116.3 0.3 1.6e-33 115.7 0.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 CAR25325.1 - 1.4e-33 114.3 0.8 2.5e-33 113.5 0.1 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain AAA_18 PF13238.1 CAR25326.1 - 6.1e-07 29.7 0.0 2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR25326.1 - 9.8e-07 29.6 0.1 4.4e-06 27.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CAR25326.1 - 7.5e-06 25.8 0.0 0.00067 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAR25326.1 - 0.00011 21.4 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 CAR25326.1 - 0.00012 21.7 0.0 0.00035 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR25326.1 - 0.00049 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 CAR25326.1 - 0.0012 18.9 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 CAR25326.1 - 0.0023 17.6 0.0 0.0073 16.0 0.0 1.9 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CAR25326.1 - 0.0025 16.7 0.0 0.0061 15.4 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.24 CAR25326.1 - 0.0036 17.5 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CAR25326.1 - 0.0041 16.0 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein 6PF2K PF01591.13 CAR25326.1 - 0.0054 15.8 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_22 PF13401.1 CAR25326.1 - 0.0054 16.8 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CAR25326.1 - 0.0094 14.9 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 CAR25326.1 - 0.01 14.6 0.0 0.02 13.6 0.0 1.4 1 0 0 1 1 1 0 ArgK protein MMR_HSR1 PF01926.18 CAR25326.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 CAR25326.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.5 CAR25326.1 - 0.024 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 CAR25326.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.6 2 0 0 2 2 1 0 ABC transporter NTPase_1 PF03266.10 CAR25326.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 CAR25326.1 - 0.028 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 CAR25326.1 - 0.032 14.1 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 CAR25326.1 - 0.037 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CAR25326.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 CAR25326.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase cobW PF02492.14 CAR25326.1 - 0.065 12.6 0.0 0.18 11.2 0.0 1.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CAR25326.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 CAR25326.1 - 0.092 12.6 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 CAR25326.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.12 CAR25326.1 - 0.11 11.8 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 CAR25326.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad21_Rec8_N PF04825.8 CAR25328.1 - 5.1e-17 61.8 0.1 1.1e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein NCD1 PF04904.8 CAR25329.1 - 0.063 13.0 1.4 0.21 11.3 0.2 2.2 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) NYD-SP28_assoc PF14775.1 CAR25329.1 - 0.1 12.3 2.0 0.71 9.6 0.3 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain DNA_pol3_a_NII PF11490.3 CAR25329.1 - 0.11 12.0 2.5 0.88 9.1 0.0 2.9 3 1 1 4 4 4 0 DNA polymerase III polC-type N-terminus II FTR1 PF03239.9 CAR25330.1 - 5.7e-101 337.4 8.6 7.1e-101 337.1 6.0 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family PrgI PF12666.2 CAR25330.1 - 2.5 8.3 14.6 0.16 12.1 0.4 3.6 3 1 1 4 4 4 0 PrgI family protein 7TM_GPCR_Srh PF10318.4 CAR25330.1 - 5.7 5.6 11.0 2.5 6.8 0.2 3.1 3 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srh Copper-fist PF00649.13 CAR25332.1 - 1.6e-21 75.1 1.0 1.6e-21 75.1 0.7 2.5 2 1 1 3 3 3 1 Copper fist DNA binding domain DUF3439 PF11921.3 CAR25332.1 - 0.32 10.7 3.5 0.76 9.5 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ran-binding PF05508.6 CAR25333.1 - 1.7e-117 391.7 4.8 2.5e-117 391.1 3.3 1.2 1 0 0 1 1 1 1 RanGTP-binding protein SNF2_N PF00176.18 CAR25334.1 - 4.3e-69 232.5 0.0 6.1e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CAR25334.1 - 1.8e-43 148.5 2.8 6.2e-43 146.8 2.2 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 CAR25334.1 - 1e-12 47.7 0.0 2.7e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CAR25334.1 - 4.1e-10 38.9 0.0 4.5e-09 35.5 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 CAR25334.1 - 0.021 14.9 0.0 0.069 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 CAR25334.1 - 0.027 14.3 0.0 0.074 12.8 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PRCC PF10253.4 CAR25334.1 - 0.047 14.3 4.1 4.6 7.9 0.2 2.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Zn_clus PF00172.13 CAR25335.1 - 0.00051 19.9 1.8 0.00051 19.9 1.2 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_synt_C PF14667.1 CAR25336.1 - 0.67 9.7 11.6 0.31 10.8 6.3 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain adh_short PF00106.20 CAR25337.1 - 5.7e-30 104.4 1.7 1.2e-29 103.3 1.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR25337.1 - 2.3e-20 73.4 0.2 3.8e-20 72.6 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR25337.1 - 6.6e-10 38.9 0.3 1.2e-09 38.1 0.2 1.3 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.1 CAR25337.1 - 0.003 17.6 0.4 3.6 7.8 0.0 3.5 3 1 0 3 3 3 1 Helix-hairpin-helix domain Epimerase PF01370.16 CAR25337.1 - 0.0049 16.3 0.1 0.0093 15.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 CAR25337.1 - 0.01 15.6 0.1 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain POR PF01558.13 CAR25337.1 - 0.034 14.0 0.1 0.074 12.9 0.1 1.6 1 1 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Radical_SAM PF04055.16 CAR25337.1 - 0.11 12.6 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Radical SAM superfamily Eno-Rase_NADH_b PF12242.3 CAR25337.1 - 0.11 12.2 0.3 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sua5_yciO_yrdC PF01300.13 CAR25338.1 - 1.1e-46 158.2 0.0 1.7e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CAR25338.1 - 4.8e-31 107.4 0.0 7.2e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF928 PF06051.7 CAR25338.1 - 0.1 12.1 0.3 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) E1-E2_ATPase PF00122.15 CAR25339.1 - 2.3e-76 255.8 0.7 4e-76 255.0 0.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CAR25339.1 - 2.9e-47 160.5 0.9 2.9e-47 160.5 0.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CAR25339.1 - 1.7e-32 113.5 0.0 4e-32 112.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CAR25339.1 - 4.2e-17 62.9 0.0 1.1e-16 61.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CAR25339.1 - 4.1e-16 58.7 0.1 1e-15 57.4 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CAR25339.1 - 2.1e-13 49.4 0.0 4.8e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CAR25339.1 - 5.1e-05 22.9 0.9 0.00056 19.5 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNA_pol_Rpb2_6 PF00562.23 CAR25340.1 - 3.8e-113 378.1 0.0 5.3e-113 377.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CAR25340.1 - 1.7e-46 157.7 0.0 2.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CAR25340.1 - 1.3e-35 122.5 0.1 2.6e-35 121.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 CAR25340.1 - 1.6e-24 85.4 0.1 8.7e-24 83.0 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CAR25340.1 - 7.1e-24 83.5 0.0 1.4e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 CAR25340.1 - 5.6e-15 55.3 0.0 3.6e-14 52.7 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CAR25340.1 - 2.4e-07 30.6 0.0 5.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PolC_DP2 PF03833.8 CAR25340.1 - 0.23 9.0 0.2 0.34 8.5 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Glyco_hydro_17 PF00332.13 CAR25341.1 - 1.7e-08 33.8 2.0 7.3e-07 28.5 0.0 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 Mid2 PF04478.7 CAR25342.1 - 2.9e-53 179.4 1.0 2.9e-53 179.4 0.7 4.0 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 CAR25342.1 - 0.047 13.0 0.1 0.047 13.0 0.1 3.9 4 0 0 4 4 4 0 Transmembrane alpha-helix domain DUF912 PF06024.7 CAR25342.1 - 7.2 6.7 8.9 22 5.1 3.6 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Thg1 PF04446.7 CAR25343.1 - 8.3e-48 161.4 1.1 1.1e-47 160.9 0.7 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 CAR25343.1 - 4.2e-36 123.3 0.4 8.1e-36 122.3 0.1 1.6 2 0 0 2 2 2 1 Thg1 C terminal domain IlvC PF01450.14 CAR25344.1 - 1.1e-47 161.6 0.0 2.4e-47 160.4 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 CAR25344.1 - 2.2e-45 154.0 0.0 3.1e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CAR25344.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AhpC-TSA PF00578.16 CAR25345.1 - 2.3e-29 101.5 0.0 2.9e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAR25345.1 - 2.1e-09 37.0 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CAR25345.1 - 9.5e-09 34.7 0.0 1.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF2464 PF10240.4 CAR25345.1 - 0.0025 17.2 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2464) zf-C2H2_4 PF13894.1 CAR25346.1 - 3.7e-07 30.0 11.3 0.034 14.4 0.2 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CAR25346.1 - 8.9e-06 25.7 9.6 0.019 15.2 0.3 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF629 PF04780.7 CAR25346.1 - 0.14 10.6 1.2 7.4 4.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 CAR25346.1 - 0.34 11.0 0.1 0.34 11.0 0.1 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) DDE_1 PF03184.14 CAR25347.1 - 2.9e-20 72.3 0.0 6.1e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease mTERF PF02536.9 CAR25347.1 - 0.00062 18.4 0.5 0.0012 17.4 0.3 1.4 1 0 0 1 1 1 1 mTERF HTH_psq PF05225.11 CAR25347.1 - 0.0026 17.2 0.3 1.7 8.2 0.0 3.1 2 0 0 2 2 2 2 helix-turn-helix, Psq domain Transaldolase PF00923.14 CAR25348.1 - 2.4e-99 332.0 2.1 2.8e-99 331.8 1.5 1.0 1 0 0 1 1 1 1 Transaldolase DUF2439 PF10382.4 CAR25349.1 - 4.7e-24 84.4 0.6 7.3e-24 83.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) zf-CCHC PF00098.18 CAR25350.1 - 9.1e-09 34.8 50.1 0.00015 21.5 3.1 5.7 6 0 0 6 6 6 3 Zinc knuckle Peptidase_M19 PF01244.16 CAR25351.1 - 5.5e-103 344.2 0.0 6.3e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.9 CAR25351.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase LRR_8 PF13855.1 CAR25353.1 - 0.0019 17.9 5.4 0.013 15.2 1.3 3.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 CAR25353.1 - 0.019 14.5 0.5 0.019 14.5 0.3 4.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Pkinase PF00069.20 CAR25354.1 - 1.9e-73 246.8 0.0 2.3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25354.1 - 1.2e-33 116.3 0.0 1.5e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR25354.1 - 5.1e-06 25.6 0.1 3.7e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR25354.1 - 0.0017 17.4 0.1 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR25354.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Dimerisation PF08100.6 CAR25354.1 - 0.021 14.6 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain CN_hydrolase PF00795.17 CAR25355.1 - 4e-36 124.1 0.0 5.5e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ORMDL PF04061.9 CAR25356.1 - 9.4e-58 193.6 4.3 1.1e-57 193.3 3.0 1.0 1 0 0 1 1 1 1 ORMDL family ACBP PF00887.14 CAR25357.1 - 2e-31 107.4 1.5 2.1e-31 107.3 1.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 CAR25357.1 - 0.0077 16.4 0.5 0.23 11.6 0.1 2.0 1 1 1 2 2 2 1 FERM central domain CENP-B_N PF04218.8 CAR25357.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HEAT_EZ PF13513.1 CAR25358.1 - 1e-16 60.8 17.9 1.3e-06 28.6 0.0 9.4 8 2 2 10 10 10 5 HEAT-like repeat HEAT_2 PF13646.1 CAR25358.1 - 1.1e-13 51.3 19.4 6.5e-07 29.5 0.0 7.5 1 1 7 8 8 8 3 HEAT repeats HEAT PF02985.17 CAR25358.1 - 8.1e-12 44.1 31.4 5.1e-05 23.0 0.0 11.9 14 0 0 14 14 14 4 HEAT repeat IBN_N PF03810.14 CAR25358.1 - 3.6e-09 36.4 0.9 3.6e-09 36.4 0.6 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 CAR25358.1 - 1.3e-05 24.8 9.6 0.0011 18.7 0.0 6.3 6 1 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CAR25358.1 - 7e-05 22.2 0.2 0.1 11.9 0.0 3.8 2 1 2 4 4 4 1 CLASP N terminal RICTOR_V PF14668.1 CAR25358.1 - 0.0076 16.1 0.7 0.35 10.8 0.1 3.7 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 PAP2 PF01569.16 CAR25359.1 - 1.9e-18 66.3 2.5 4e-18 65.3 1.7 1.4 1 0 0 1 1 1 1 PAP2 superfamily 6PF2K PF01591.13 CAR25360.1 - 4.8e-63 212.1 2.0 6.6e-63 211.7 1.4 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CAR25360.1 - 2.5e-20 73.1 0.0 5.5e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CAR25360.1 - 0.00043 20.1 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KOW PF00467.24 CAR25361.1 - 1.2e-05 24.8 1.7 1.7e-05 24.3 0.4 1.8 2 0 0 2 2 2 1 KOW motif TIM21 PF08294.6 CAR25362.1 - 4.4e-52 175.5 0.0 5.4e-52 175.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 Glyco_hydro_72 PF03198.9 CAR25363.1 - 1.3e-132 441.5 0.8 1.8e-132 441.1 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CAR25363.1 - 4.3e-17 62.3 0.8 1e-16 61.1 0.5 1.7 1 0 0 1 1 1 1 X8 domain Glucan_synthase PF02364.10 CAR25364.1 - 0 1452.6 0.0 0 1451.8 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CAR25364.1 - 3.8e-39 133.2 0.1 1.6e-38 131.1 0.0 2.2 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Abhydrolase_6 PF12697.2 CAR25365.1 - 2.4e-29 102.8 0.0 3.1e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR25365.1 - 5.9e-17 61.9 0.0 9.8e-17 61.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR25365.1 - 3.6e-12 46.2 0.0 5.9e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CAR25365.1 - 2.9e-06 27.0 0.0 5.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 CAR25365.1 - 0.0017 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 CAR25365.1 - 0.018 14.4 0.1 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 CAR25365.1 - 0.019 15.2 0.0 0.097 12.8 0.0 2.0 1 1 1 2 2 2 0 Thioesterase domain Ribosomal_L10 PF00466.15 CAR25367.1 - 2.8e-27 94.5 0.1 4.8e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CAR25367.1 - 2.1e-17 63.2 1.8 3e-16 59.5 0.6 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein Alba PF01918.16 CAR25368.1 - 1.6e-05 24.3 0.1 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Alba DUF3445 PF11927.3 CAR25369.1 - 1.2e-74 250.8 0.0 1.9e-74 250.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) WH2 PF02205.15 CAR25370.1 - 4.3e-14 51.5 0.9 3.2e-10 39.2 0.1 3.1 3 0 0 3 3 3 2 WH2 motif Evr1_Alr PF04777.8 CAR25371.1 - 3.1e-30 103.9 3.8 3.1e-30 103.9 2.6 1.6 2 0 0 2 2 2 1 Erv1 / Alr family AAA PF00004.24 CAR25372.1 - 1.9e-37 128.3 0.0 3.4e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CAR25372.1 - 4.9e-07 29.6 0.0 1.4e-06 28.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CAR25372.1 - 1e-06 29.5 0.1 3.1e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CAR25372.1 - 4e-06 26.9 0.7 0.00081 19.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 CAR25372.1 - 1.1e-05 25.3 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CAR25372.1 - 1.3e-05 25.3 0.3 0.0012 19.0 0.1 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CAR25372.1 - 1.7e-05 23.9 0.0 6.5e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CAR25372.1 - 2.4e-05 24.2 0.0 9e-05 22.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CAR25372.1 - 5.8e-05 22.8 0.2 0.0004 20.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 CAR25372.1 - 0.00027 21.0 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 CAR25372.1 - 0.00041 20.6 0.0 0.00085 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CAR25372.1 - 0.00044 19.7 0.0 0.00088 18.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CAR25372.1 - 0.0005 19.2 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 CAR25372.1 - 0.00098 17.9 0.1 0.0021 16.8 0.1 1.5 1 1 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CAR25372.1 - 0.0013 17.9 0.3 0.0033 16.6 0.2 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CAR25372.1 - 0.0016 18.6 0.0 0.0054 16.8 0.0 2.0 2 1 0 2 2 2 1 RNA helicase Rad17 PF03215.10 CAR25372.1 - 0.0017 17.1 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 CAR25372.1 - 0.002 17.6 0.0 0.0083 15.6 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CAR25372.1 - 0.0031 17.2 0.1 0.014 15.1 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 CAR25372.1 - 0.0036 16.7 0.8 0.31 10.4 0.1 2.3 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CAR25372.1 - 0.004 16.1 0.0 0.0075 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.7 CAR25372.1 - 0.0082 15.8 0.2 0.025 14.2 0.1 1.9 2 0 0 2 2 1 1 NACHT domain AAA_28 PF13521.1 CAR25372.1 - 0.0099 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR25372.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CAR25372.1 - 0.013 15.0 0.0 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.7 CAR25372.1 - 0.015 14.9 0.2 0.031 13.8 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.6 CAR25372.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CAR25372.1 - 0.018 15.3 0.0 0.055 13.7 0.0 2.0 2 1 0 2 2 2 0 ABC transporter SKI PF01202.17 CAR25372.1 - 0.02 14.7 0.5 0.069 13.0 0.0 2.2 3 0 0 3 3 2 0 Shikimate kinase SRPRB PF09439.5 CAR25372.1 - 0.041 13.0 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit KTI12 PF08433.5 CAR25372.1 - 0.058 12.5 0.1 0.66 9.1 0.0 2.6 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 CAR25372.1 - 0.06 12.2 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA_lig_kinase PF08303.6 CAR25372.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain NB-ARC PF00931.17 CAR25372.1 - 0.065 12.0 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 CAR25372.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MA3 PF02847.12 CAR25373.1 - 3.1e-23 81.6 0.3 9.3e-23 80.0 0.2 1.9 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 CAR25373.1 - 2.1e-22 79.5 1.2 2.1e-22 79.5 0.9 2.4 2 0 0 2 2 2 1 MIF4G domain Ran_BP1 PF00638.13 CAR25374.1 - 2.3e-32 111.5 1.0 3.4e-32 111.0 0.1 1.7 2 0 0 2 2 2 1 RanBP1 domain NUP50 PF08911.6 CAR25374.1 - 5e-17 62.0 2.7 5e-17 62.0 1.9 3.9 4 1 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ribosomal_S25 PF03297.10 CAR25375.1 - 1e-42 144.4 4.7 1.2e-42 144.2 3.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 CAR25375.1 - 0.00023 20.7 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain Ribosomal_S4 PF00163.14 CAR25375.1 - 0.044 14.1 0.7 0.066 13.6 0.5 1.3 1 1 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain DUF365 PF04033.7 CAR25375.1 - 0.075 13.0 0.3 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) RepB PF07506.6 CAR25375.1 - 0.12 12.2 0.5 0.19 11.5 0.3 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein DUF1980 PF09323.5 CAR25375.1 - 0.13 11.9 0.2 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SNF2_N PF00176.18 CAR25377.1 - 2e-37 128.6 0.0 4.3e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CAR25377.1 - 1.2e-09 37.8 8.7 2.9e-09 36.6 6.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CAR25377.1 - 3.5e-08 32.9 8.7 9.6e-08 31.5 6.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR25377.1 - 1.4e-07 31.0 6.7 2.9e-07 30.0 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR25377.1 - 2.8e-07 30.4 10.3 7.2e-07 29.1 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 CAR25377.1 - 0.00015 21.5 0.0 0.00044 20.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CAR25377.1 - 0.00027 20.5 9.0 0.00069 19.2 6.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CAR25377.1 - 0.00028 20.9 8.4 0.00085 19.3 5.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CAR25377.1 - 0.00044 20.0 10.0 0.0011 18.7 6.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CAR25377.1 - 0.021 14.3 3.5 0.055 13.0 2.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 CAR25377.1 - 0.045 13.5 3.1 0.12 12.1 2.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CAR25377.1 - 0.052 13.2 4.2 0.22 11.2 2.9 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 CAR25377.1 - 0.24 10.9 7.1 0.89 9.0 4.9 2.0 1 0 0 1 1 1 0 P-11 zinc finger Pkinase PF00069.20 CAR25379.1 - 8.5e-50 169.3 0.0 1.1e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25379.1 - 2.6e-27 95.5 0.0 3.6e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR25379.1 - 4.7e-07 29.0 0.0 1.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CAR25379.1 - 0.00017 21.4 0.2 0.046 13.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CAR25379.1 - 0.045 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CAR25379.1 - 0.17 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 eIF2A PF08662.6 CAR25381.1 - 3.1e-77 258.6 0.0 9.7e-77 257.0 0.0 1.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CAR25381.1 - 0.0024 17.7 3.1 8.2 6.4 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat Pkinase PF00069.20 CAR25383.1 - 2.2e-29 102.3 0.0 3.8e-29 101.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25383.1 - 1.2e-15 57.2 0.0 1.9e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR25383.1 - 0.00018 21.3 0.0 0.0006 19.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR25383.1 - 0.0003 19.9 0.1 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CAR25383.1 - 0.011 15.0 0.1 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FA_hydroxylase PF04116.8 CAR25384.1 - 2.7e-11 43.8 17.2 2.7e-11 43.8 11.9 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily ABC_tran PF00005.22 CAR25385.1 - 7.3e-17 61.9 0.3 6e-16 58.9 0.1 2.3 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CAR25385.1 - 1.2e-10 41.8 3.1 0.00011 22.2 0.0 2.2 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CAR25385.1 - 6.2e-07 28.8 0.0 6.3e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CAR25385.1 - 3.6e-06 26.2 0.0 0.037 13.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 CAR25385.1 - 6.9e-05 23.2 0.0 8.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CAR25385.1 - 0.00014 21.2 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CAR25385.1 - 0.00084 18.5 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CAR25385.1 - 0.0025 17.3 0.0 0.0057 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 CAR25385.1 - 0.0062 17.3 0.7 0.014 16.2 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CAR25385.1 - 0.029 13.9 0.2 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CAR25385.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 CAR25385.1 - 0.051 13.4 0.3 0.085 12.6 0.2 1.3 1 0 0 1 1 1 0 Dynamin family DUF3584 PF12128.3 CAR25385.1 - 0.057 10.7 0.0 0.076 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.18 CAR25385.1 - 0.074 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.1 CAR25385.1 - 0.13 10.7 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CAR25385.1 - 0.14 11.5 0.1 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.4 CAR25385.1 - 0.16 11.4 0.3 0.25 10.8 0.2 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.27 CAR25386.1 - 5.6e-16 57.7 5.2 8.1e-05 22.3 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat RabGAP-TBC PF00566.13 CAR25387.1 - 1.9e-17 63.4 0.0 5.1e-17 62.0 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Myb_DNA-bind_4 PF13837.1 CAR25388.1 - 1.4e-06 28.3 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4349 PF14257.1 CAR25388.1 - 0.028 13.6 0.4 0.028 13.6 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Myb_DNA-bind_6 PF13921.1 CAR25388.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CAR25389.1 - 0.00063 19.8 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CAR25389.1 - 0.01 15.7 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Glyco_hydro_47 PF01532.15 CAR25392.1 - 1.7e-85 287.3 0.0 2.2e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SHMT PF00464.14 CAR25393.1 - 1.3e-209 695.5 0.0 1.5e-209 695.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 CAR25393.1 - 1.1e-06 27.8 0.0 2.2e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CAR25393.1 - 2.1e-06 26.7 0.0 2.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR25393.1 - 0.00044 19.4 0.0 0.00082 18.6 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase FR47 PF08445.5 CAR25393.1 - 0.071 12.8 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Aminotran_5 PF00266.14 CAR25394.1 - 7.2e-24 84.2 0.0 9.4e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CAR25394.1 - 0.0064 15.4 0.1 0.013 14.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.14 CAR25394.1 - 0.01 15.6 0.5 0.065 13.1 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain DnaJ PF00226.26 CAR25395.1 - 1.5e-19 69.4 0.5 1.1e-18 66.6 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain SHOCT PF09851.4 CAR25395.1 - 0.047 13.1 2.5 8.9 5.9 0.3 3.3 2 0 0 2 2 2 0 Short C-terminal domain FeoC PF09012.5 CAR25395.1 - 0.058 13.1 2.0 2.7 7.7 0.7 3.0 2 1 1 3 3 3 0 FeoC like transcriptional regulator Toxin_64 PF15542.1 CAR25395.1 - 0.15 12.6 3.8 0.41 11.2 2.7 1.8 1 0 0 1 1 1 0 Putative toxin 64 DUF1788 PF08747.6 CAR25395.1 - 0.64 9.8 5.8 0.25 11.1 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1788) bZIP_2 PF07716.10 CAR25396.1 - 0.00015 21.4 10.0 0.00015 21.4 7.0 1.8 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CAR25396.1 - 0.0031 17.4 12.5 0.021 14.8 8.7 2.1 1 1 0 1 1 1 1 bZIP transcription factor RNase_T PF00929.19 CAR25397.1 - 2.9e-33 115.4 0.3 5.2e-33 114.6 0.2 1.4 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.20 CAR25398.1 - 7.8e-57 192.3 0.0 1.9e-35 122.2 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CAR25398.1 - 7.4e-26 90.7 0.1 2.2e-19 69.5 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR25398.1 - 8.4e-08 31.5 0.0 8.1e-06 25.0 0.0 2.5 1 1 1 2 2 2 1 Kinase-like Response_reg PF00072.19 CAR25398.1 - 2.4e-07 30.7 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 CAR25398.1 - 0.0011 19.2 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain APH PF01636.18 CAR25398.1 - 0.0012 18.6 0.0 0.072 12.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CAR25398.1 - 0.006 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAR25398.1 - 0.056 12.7 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 RIO1 family PAS_4 PF08448.5 CAR25398.1 - 0.079 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 CAR25398.1 - 0.087 11.6 1.0 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 B3_4 PF03483.12 CAR25399.1 - 2e-29 102.2 0.0 3.3e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CAR25399.1 - 2.8e-20 71.9 0.0 1.1e-17 63.6 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF3533 PF12051.3 CAR25399.1 - 0.12 11.1 0.2 0.42 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) DUF726 PF05277.7 CAR25400.1 - 9e-134 445.7 1.2 1.8e-133 444.7 0.8 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 CAR25400.1 - 0.021 14.4 0.1 0.078 12.5 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Ribosomal_L22e PF01776.12 CAR25401.1 - 2.8e-43 146.4 1.7 3.3e-43 146.2 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family RIB43A PF05914.7 CAR25401.1 - 0.044 12.4 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 RIB43A DUF3115 PF11312.3 CAR25402.1 - 2.8e-97 325.3 0.0 3.3e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Mob1_phocein PF03637.12 CAR25403.1 - 3.5e-70 235.2 1.1 5e-70 234.7 0.7 1.2 1 0 0 1 1 1 1 Mob1/phocein family RAB3GAP2_N PF14655.1 CAR25403.1 - 0.11 11.4 2.6 0.15 11.0 1.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RNA_pol PF00940.14 CAR25404.1 - 2e-167 556.7 0.0 3.4e-167 556.0 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CAR25404.1 - 4.5e-89 298.8 1.9 1.1e-88 297.5 1.3 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Tubulin PF00091.20 CAR25405.1 - 1.6e-69 234.0 0.0 2.9e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAR25405.1 - 1.8e-48 163.7 0.1 3.7e-48 162.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CAR25405.1 - 0.0019 17.6 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CAR25405.1 - 0.0092 16.0 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain MVL PF12151.3 CAR25405.1 - 0.083 12.5 0.0 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 Mannan-binding protein Ras PF00071.17 CAR25406.1 - 2.3e-64 215.6 0.4 2.7e-64 215.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR25406.1 - 3.7e-20 72.6 0.5 5.5e-20 72.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR25406.1 - 1.2e-17 63.6 0.2 1.6e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CAR25406.1 - 9.9e-07 28.1 0.3 1.5e-06 27.5 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR25406.1 - 4.2e-05 23.0 0.2 9.8e-05 21.8 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR25406.1 - 4.6e-05 23.3 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CAR25406.1 - 0.00081 18.6 0.5 0.001 18.2 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CAR25406.1 - 0.01 15.1 0.1 0.098 11.9 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 CAR25406.1 - 0.014 15.4 0.0 0.024 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CAR25406.1 - 0.024 13.8 0.1 0.058 12.5 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 CAR25406.1 - 0.027 14.6 0.1 1.1 9.4 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 CAR25406.1 - 0.028 13.4 0.1 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 CAR25406.1 - 0.035 14.3 0.6 0.15 12.3 0.4 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CAR25406.1 - 0.035 14.0 0.2 0.11 12.4 0.1 1.9 2 1 1 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 CAR25406.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CAR25406.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 CAR25406.1 - 1.9 7.1 6.1 2.8 6.5 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit DUF788 PF05620.6 CAR25407.1 - 1.4e-45 155.1 0.0 1.6e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF3529 PF12046.3 CAR25407.1 - 0.018 14.0 0.3 0.037 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) Actin PF00022.14 CAR25408.1 - 1.6e-159 530.5 0.0 1.8e-159 530.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CAR25408.1 - 0.06 13.7 0.0 0.18 12.1 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Sugar_tr PF00083.19 CAR25409.1 - 1e-73 248.4 29.9 1.2e-73 248.2 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR25409.1 - 3.5e-23 81.9 38.3 2.1e-20 72.7 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CAR25409.1 - 0.00051 18.3 2.6 0.00051 18.3 1.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Arteri_Gl PF00951.13 CAR25409.1 - 0.0049 16.4 1.1 0.0049 16.4 0.7 3.1 3 1 0 3 3 3 1 Arterivirus GL envelope glycoprotein YrhC PF14143.1 CAR25409.1 - 0.036 14.0 2.6 2 8.4 0.2 3.7 2 1 2 4 4 4 0 YrhC-like protein Peptidase_M56 PF05569.6 CAR25409.1 - 0.47 9.3 3.0 7.7 5.3 0.1 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 SPC22 PF04573.7 CAR25410.1 - 1.1e-53 181.0 0.1 1.3e-53 180.8 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PPR_2 PF13041.1 CAR25411.1 - 2e-17 62.8 8.3 0.00052 19.9 0.0 7.7 6 2 2 8 8 8 4 PPR repeat family PPR_3 PF13812.1 CAR25411.1 - 8.2e-16 56.9 2.1 0.75 10.2 0.0 10.9 11 0 0 11 11 11 4 Pentatricopeptide repeat domain PPR PF01535.15 CAR25411.1 - 2.2e-11 42.8 11.2 0.21 11.6 0.0 8.0 8 0 0 8 8 8 5 PPR repeat TPR_14 PF13428.1 CAR25411.1 - 0.001 19.5 0.0 4 8.3 0.0 5.4 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CAR25411.1 - 0.0057 16.9 1.2 2.2 8.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat rRNA_processing PF08524.6 CAR25412.1 - 3.1e-38 130.8 30.5 4e-38 130.5 21.1 1.0 1 0 0 1 1 1 1 rRNA processing RVP PF00077.15 CAR25412.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease G6PD_N PF00479.17 CAR25412.1 - 0.72 10.0 9.9 1.1 9.5 6.8 1.3 1 1 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Neurexophilin PF06312.7 CAR25412.1 - 1.2 8.3 4.9 0.62 9.2 1.5 1.7 1 1 1 2 2 2 0 Neurexophilin DUF87 PF01935.12 CAR25412.1 - 1.5 8.5 6.2 1.8 8.2 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 RR_TM4-6 PF06459.7 CAR25412.1 - 3.6 7.3 13.5 4.1 7.2 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hex_IIIa PF02455.11 CAR25412.1 - 4 6.0 10.6 4.8 5.7 7.3 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) GTP_EFTU PF00009.22 CAR25413.1 - 1.4e-59 200.7 0.4 3.6e-59 199.3 0.1 1.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CAR25413.1 - 6.4e-35 119.3 0.0 2.3e-34 117.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CAR25413.1 - 1.4e-29 101.7 0.0 4.2e-29 100.2 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 CAR25413.1 - 9.8e-25 86.2 0.0 2.4e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CAR25413.1 - 2.3e-12 46.8 0.3 6.4e-12 45.4 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR25413.1 - 0.0072 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF442 PF04273.8 CAR25413.1 - 0.018 14.8 0.1 0.98 9.2 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Miro PF08477.8 CAR25413.1 - 0.062 13.7 0.1 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Pescadillo_N PF06732.6 CAR25413.1 - 0.093 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pescadillo N-terminus Cu-oxidase_2 PF07731.9 CAR25414.1 - 1.2e-41 141.4 8.2 1.8e-38 131.1 0.4 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CAR25414.1 - 7.7e-37 125.6 4.4 6.6e-36 122.6 0.4 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 CAR25414.1 - 9.2e-34 116.6 5.1 1.7e-29 102.7 0.5 3.2 3 0 0 3 3 3 2 Multicopper oxidase ADH_N PF08240.7 CAR25415.1 - 5.2e-27 93.7 0.2 1.1e-26 92.7 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR25415.1 - 1.5e-24 85.9 0.2 2.2e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CAR25415.1 - 3e-06 28.1 0.0 6.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 CAR25415.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 CAR25415.1 - 0.025 13.7 0.1 0.075 12.1 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Med14 PF08638.6 CAR25416.1 - 1.9e-60 203.4 2.4 3.9e-60 202.4 1.7 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 GRAM PF02893.15 CAR25417.1 - 2.8e-17 61.9 0.1 5.6e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain NOA36 PF06524.7 CAR25417.1 - 3.1 6.9 8.3 5.3 6.2 5.7 1.2 1 0 0 1 1 1 0 NOA36 protein USP8_dimer PF08969.6 CAR25418.1 - 2.5e-07 30.6 0.0 4.4e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 USP8 dimerisation domain OTU PF02338.14 CAR25419.1 - 1.6e-10 41.5 0.0 3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF1995 PF09353.5 CAR25419.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) BIR PF00653.16 CAR25419.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 CAR25420.1 - 1.1e-09 38.1 7.4 7e-09 35.5 2.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CAR25420.1 - 0.00043 20.3 0.2 0.00095 19.2 0.1 1.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CAR25420.1 - 0.042 14.0 5.4 0.19 11.9 1.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-U1 PF06220.7 CAR25420.1 - 0.061 12.8 1.5 0.11 12.0 1.1 1.4 1 0 0 1 1 1 0 U1 zinc finger AF0941-like PF14591.1 CAR25420.1 - 0.13 12.3 1.4 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 AF0941-like zf-C2H2_4 PF13894.1 CAR25420.1 - 0.17 12.2 2.1 0.31 11.4 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR25420.1 - 0.75 10.2 3.1 1.3 9.4 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Ribosomal_L16 PF00252.13 CAR25421.1 - 4.2e-34 117.1 0.2 5.4e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PMM PF03332.8 CAR25422.1 - 2.2e-113 377.2 0.4 2.5e-113 377.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CAR25422.1 - 1.2e-05 25.0 0.0 0.00015 21.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 CAR25422.1 - 0.011 14.7 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2608 PF11019.3 CAR25422.1 - 0.076 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Hydrolase PF00702.21 CAR25422.1 - 0.096 13.0 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1640 PF07798.6 CAR25423.1 - 5.5e-62 208.9 5.6 6.2e-62 208.7 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3523 PF12037.3 CAR25423.1 - 0.0073 15.3 4.9 0.0096 14.9 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) DUF3410 PF11890.3 CAR25423.1 - 0.0094 15.5 0.3 0.0094 15.5 0.2 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3410) FlaC_arch PF05377.6 CAR25423.1 - 0.027 14.3 2.0 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ApoLp-III PF07464.6 CAR25423.1 - 0.031 14.3 4.4 0.076 13.0 2.1 2.2 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Chalcone PF02431.10 CAR25423.1 - 0.037 13.4 0.5 0.046 13.1 0.4 1.3 1 0 0 1 1 1 0 Chalcone-flavanone isomerase TBPIP PF07106.8 CAR25423.1 - 0.074 12.6 6.8 0.13 11.7 4.7 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 CAR25423.1 - 0.11 12.2 3.0 0.3 10.8 0.4 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper cwf21 PF08312.7 CAR25423.1 - 0.4 10.5 4.8 0.14 12.0 0.6 2.3 2 0 0 2 2 2 0 cwf21 domain YjfB_motility PF14070.1 CAR25423.1 - 0.41 10.4 3.1 7.3 6.4 0.7 2.3 2 0 0 2 2 2 0 Putative motility protein COG2 PF06148.6 CAR25423.1 - 0.48 10.2 6.1 0.23 11.3 1.0 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 CAR25423.1 - 0.74 9.6 3.3 9.6 6.0 2.3 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_lysis PF03245.8 CAR25423.1 - 1.3 9.0 6.5 0.75 9.8 0.2 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF1732 PF08340.6 CAR25423.1 - 1.7 8.5 6.7 2.2 8.1 4.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) YlqD PF11068.3 CAR25423.1 - 1.8 8.5 8.2 0.35 10.9 2.1 2.0 1 1 2 3 3 3 0 YlqD protein RCC1 PF00415.13 CAR25424.1 - 4.4e-29 100.4 1.1 3.4e-09 36.7 0.1 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAR25424.1 - 6.6e-14 51.0 18.9 1.6e-09 37.1 0.2 5.1 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat EcoRII-N PF09217.5 CAR25424.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal V-SNARE_C PF12352.3 CAR25425.1 - 1.9e-05 24.6 2.2 1.9e-05 24.6 1.5 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CAR25425.1 - 0.0005 19.7 0.3 0.0005 19.7 0.2 2.1 2 0 0 2 2 2 1 Sec20 DUF4482 PF14818.1 CAR25425.1 - 0.02 15.5 1.9 0.042 14.5 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Retrotrans_gag PF03732.12 CAR25425.1 - 0.062 13.3 0.5 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Bap31 PF05529.7 CAR25425.1 - 0.066 12.6 3.2 0.13 11.6 2.2 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Rotamase PF00639.16 CAR25425.1 - 0.16 12.7 2.0 0.39 11.4 1.4 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain EMP24_GP25L PF01105.19 CAR25425.1 - 0.19 11.4 4.4 1.3 8.7 0.4 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.14 CAR25425.1 - 0.22 9.3 8.2 0.097 10.5 4.5 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FliD_N PF02465.13 CAR25425.1 - 0.89 9.9 6.2 0.27 11.6 1.5 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CENP-H PF05837.7 CAR25425.1 - 0.92 9.7 6.6 1.9 8.6 1.5 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Cortex-I_coil PF09304.5 CAR25425.1 - 3 7.9 13.7 0.057 13.4 3.0 2.6 3 1 0 3 3 3 0 Cortexillin I, coiled coil Allexi_40kDa PF05549.6 CAR25425.1 - 3.6 6.8 5.6 0.97 8.6 1.9 1.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein FCH PF00611.18 CAR25427.1 - 1.6e-12 47.4 2.6 3.3e-12 46.4 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 CAR25427.1 - 3.5e-12 45.8 0.3 2e-11 43.4 0.1 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 CAR25427.1 - 9.6e-11 41.5 0.2 9.6e-11 41.5 0.1 2.9 3 0 0 3 3 3 1 RhoGAP domain Rdx PF10262.4 CAR25428.1 - 1.5e-26 92.1 0.0 1.9e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Rdx family Lectin_leg-like PF03388.8 CAR25429.1 - 7e-43 146.3 0.1 9.5e-43 145.9 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family DUF1690 PF07956.6 CAR25429.1 - 3.1 7.7 8.1 15 5.5 0.0 2.3 1 1 0 2 2 2 0 Protein of Unknown function (DUF1690) CRC_subunit PF08624.5 CAR25430.1 - 3.3e-37 127.5 0.0 5.6e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit NODP PF07684.7 CAR25430.1 - 0.047 13.2 0.2 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 NOTCH protein Lyase_1 PF00206.15 CAR25431.1 - 8.1e-97 324.1 0.0 1.2e-96 323.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CAR25431.1 - 9.9e-25 86.4 0.0 2.9e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal adh_short PF00106.20 CAR25432.1 - 5.4e-08 32.9 1.4 1.3e-07 31.7 1.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CAR25432.1 - 7.3e-06 25.5 0.1 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CAR25432.1 - 1.7e-05 24.8 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 CAR25432.1 - 0.00055 19.1 0.1 0.00085 18.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CAR25432.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CAR25432.1 - 0.0053 16.1 0.1 0.0092 15.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA KR PF08659.5 CAR25432.1 - 0.017 14.7 0.2 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.1 CAR25432.1 - 0.025 14.3 0.0 0.87 9.3 0.0 2.3 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 CAR25432.1 - 0.058 13.8 0.2 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CAR25432.1 - 0.099 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 CAR25432.1 - 0.17 11.0 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Flocculin_t3 PF13928.1 CAR25433.1 - 0.00011 22.2 11.5 0.00011 22.2 8.0 7.6 5 2 1 6 6 6 2 Flocculin type 3 repeat Sugar_tr PF00083.19 CAR25434.1 - 9e-131 436.5 23.6 1e-130 436.3 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR25434.1 - 7.4e-21 74.2 33.3 1.6e-17 63.2 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.8 CAR25434.1 - 0.21 11.6 0.1 0.58 10.2 0.0 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-BED PF02892.10 CAR25435.1 - 6.4e-07 29.0 1.5 1.5e-06 27.8 1.1 1.6 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.9 CAR25435.1 - 8.5e-06 25.3 0.0 2.5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2_4 PF13894.1 CAR25435.1 - 0.19 12.1 2.4 1 9.8 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger ABC2_membrane PF01061.19 CAR25436.1 - 1.9e-84 282.0 50.3 2.6e-43 147.6 11.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CAR25436.1 - 8.9e-41 139.3 0.1 3.2e-19 69.5 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 CAR25436.1 - 4e-39 132.4 11.8 2.4e-36 123.4 0.2 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CAR25436.1 - 6.2e-24 83.8 0.1 2.2e-23 82.1 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CAR25436.1 - 1.3e-09 37.7 0.1 3.6e-06 26.4 0.0 3.2 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 CAR25436.1 - 1.4e-09 38.2 0.0 3e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CAR25436.1 - 7.8e-06 25.1 0.0 0.001 18.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CAR25436.1 - 4.6e-05 22.8 1.6 0.0035 16.8 0.3 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 CAR25436.1 - 0.0002 21.2 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CAR25436.1 - 0.00022 21.5 0.8 0.064 13.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CAR25436.1 - 0.00034 20.3 0.0 0.18 11.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ABC2_membrane_3 PF12698.2 CAR25436.1 - 0.0012 17.9 48.0 0.031 13.3 14.8 3.4 3 2 1 4 4 4 2 ABC-2 family transporter protein SMC_N PF02463.14 CAR25436.1 - 0.0013 17.9 0.0 0.23 10.6 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 CAR25436.1 - 0.0015 18.5 0.1 0.053 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CAR25436.1 - 0.0031 17.0 0.7 0.23 10.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CAR25436.1 - 0.0036 17.4 1.3 0.48 10.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_21 PF13304.1 CAR25436.1 - 0.0043 17.0 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CAR25436.1 - 0.0064 16.2 0.3 1.8 8.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_23 PF13476.1 CAR25436.1 - 0.025 14.9 4.6 0.049 13.9 0.0 3.2 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.18 CAR25436.1 - 0.03 14.2 0.1 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CAR25436.1 - 0.044 14.5 0.0 8.2 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 CAR25436.1 - 0.072 12.6 0.3 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 CAR25436.1 - 0.081 12.5 0.2 0.9 9.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 CAR25436.1 - 0.43 9.9 2.6 16 4.7 0.0 2.9 3 1 1 4 4 4 0 AAA-like domain Alpha-amylase PF00128.19 CAR25437.1 - 6e-100 334.6 0.0 9.9e-100 333.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF4434 PF14488.1 CAR25437.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Ldh_1_N PF00056.18 CAR25439.1 - 6.1e-44 149.2 0.5 9.3e-44 148.6 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAR25439.1 - 2.6e-32 111.9 0.0 4.5e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.9 CAR25439.1 - 0.00018 20.9 0.8 0.0011 18.4 0.6 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.11 CAR25439.1 - 0.00086 18.6 0.3 0.0069 15.7 0.0 2.3 2 1 0 2 2 2 1 Family 4 glycosyl hydrolase AlaDh_PNT_C PF01262.16 CAR25439.1 - 0.019 14.5 0.5 0.039 13.5 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CAR25439.1 - 0.022 14.4 0.2 0.044 13.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 CAR25439.1 - 0.033 14.0 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 CAR25439.1 - 0.041 13.8 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 CAR25439.1 - 0.064 12.1 0.2 0.084 11.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ldh_1_N PF00056.18 CAR25440.1 - 3.7e-42 143.4 0.9 6.4e-42 142.7 0.6 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CAR25440.1 - 2.6e-37 128.2 0.2 7.8e-37 126.6 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 CAR25440.1 - 0.0001 21.7 1.8 0.00028 20.2 0.1 2.4 2 1 1 3 3 3 1 Family 4 glycosyl hydrolase ThiF PF00899.16 CAR25440.1 - 0.00011 22.0 0.3 0.00026 20.8 0.2 1.6 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 CAR25440.1 - 0.00036 20.7 0.4 0.00076 19.7 0.3 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.19 CAR25440.1 - 0.00067 18.6 0.1 0.00099 18.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 CAR25440.1 - 0.0054 16.1 2.3 0.03 13.6 0.2 2.5 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 CAR25440.1 - 0.0061 15.5 0.0 0.0085 15.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CAR25440.1 - 0.0086 15.7 0.1 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CAR25440.1 - 0.034 14.2 0.4 0.071 13.2 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 CAR25440.1 - 0.046 13.7 1.9 0.059 13.3 0.4 2.0 2 1 0 2 2 2 0 TrkA-N domain DUP PF00674.13 CAR25441.1 - 6.7e-21 74.2 3.7 3.1e-12 46.4 0.1 2.5 2 1 0 2 2 2 2 DUP family Peptidase_M50 PF02163.17 CAR25441.1 - 0.34 9.8 1.9 0.75 8.7 1.3 1.5 1 0 0 1 1 1 0 Peptidase family M50 Pyr_redox_2 PF07992.9 CAR25442.1 - 1.3e-18 67.5 0.0 2.5e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR25442.1 - 1.9e-11 44.1 0.2 4.9e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR25442.1 - 5.2e-11 42.9 1.0 1.2e-05 25.4 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CAR25442.1 - 3.4e-08 32.8 0.7 7.4e-06 25.0 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CAR25442.1 - 0.058 13.6 0.1 0.52 10.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding KOW PF00467.24 CAR25442.1 - 0.072 12.8 1.4 5.4 6.9 0.1 3.1 3 0 0 3 3 3 0 KOW motif UnbV_ASPIC PF07593.7 CAR25442.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 ASPIC and UnbV FAD_binding_3 PF01494.14 CAR25442.1 - 0.16 11.0 1.1 3.8 6.4 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Aminotran_1_2 PF00155.16 CAR25443.1 - 2e-16 59.9 0.0 2.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CAR25443.1 - 2.5e-05 23.0 0.0 0.00011 20.9 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.16 CAR25444.1 - 3.3e-44 151.3 0.0 3.9e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CAR25444.1 - 2.2e-06 27.0 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CAR25444.1 - 1.6e-05 23.8 0.0 2.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CAR25444.1 - 3.6e-05 22.2 0.0 4.9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CAR25444.1 - 0.0027 16.7 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 CAR25444.1 - 0.0052 15.4 0.0 0.0076 14.9 0.0 1.2 1 0 0 1 1 1 1 Allinase Ribosomal_S14 PF00253.16 CAR25444.1 - 0.047 13.0 0.4 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Aminotran_MocR PF12897.2 CAR25444.1 - 0.064 11.8 0.0 0.088 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase MFS_1 PF07690.11 CAR25445.1 - 1.3e-40 139.2 27.2 1.9e-40 138.6 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Mannosyl_trans3 PF11051.3 CAR25446.1 - 5.3e-66 222.7 0.1 1.1e-65 221.6 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 CAR25446.1 - 0.081 12.2 0.3 0.18 11.1 0.2 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 8 adh_short PF00106.20 CAR25448.1 - 9.1e-08 32.1 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CAR25448.1 - 2.3e-05 24.4 0.1 3.5e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CAR25448.1 - 0.00063 19.2 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 CAR25448.1 - 0.0022 17.1 0.1 0.005 16.0 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.5 CAR25448.1 - 0.0072 16.0 0.3 0.015 14.9 0.2 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CAR25448.1 - 0.011 15.4 0.0 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 CAR25448.1 - 0.036 12.9 0.1 0.051 12.4 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Oxidored_nitro PF00148.14 CAR25448.1 - 0.038 12.6 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase THF_DHG_CYH_C PF02882.14 CAR25448.1 - 0.049 12.7 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 CAR25448.1 - 0.057 13.7 0.1 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ETF PF01012.16 CAR25448.1 - 0.076 12.7 0.1 5.7 6.6 0.0 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein domain Glyco_transf_4 PF13439.1 CAR25448.1 - 0.14 11.8 0.2 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Alkyl_sulf_dimr PF14863.1 CAR25449.1 - 1.7e-58 196.8 0.5 3e-58 196.0 0.3 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 CAR25449.1 - 5.7e-35 120.0 0.4 1.1e-34 119.0 0.3 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 CAR25449.1 - 1e-32 113.3 0.1 1.9e-32 112.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CAR25449.1 - 5.3e-05 22.8 0.0 0.00018 21.1 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SCP2 PF02036.12 CAR25449.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Lactamase_B_3 PF13483.1 CAR25449.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Amidohydro_1 PF01979.15 CAR30025.1 - 2.3e-30 106.3 0.3 4.1e-30 105.5 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CAR30025.1 - 4.5e-15 56.4 0.0 7.3e-14 52.4 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 CAR30025.1 - 1.5e-12 47.1 0.0 7.9e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CAR30025.1 - 1.6e-11 44.0 2.9 1.7e-09 37.4 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Acetyltransf_8 PF13523.1 CAR30027.1 - 1.2e-08 35.0 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR30027.1 - 2e-07 30.9 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CAR30027.1 - 2e-05 24.7 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CAR30027.1 - 0.00042 20.4 0.0 0.00076 19.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR30027.1 - 0.0022 18.1 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.22 CAR30028.1 - 6e-57 189.3 2.2 2.1e-19 69.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_10 PF13460.1 CAR30029.1 - 3.1e-09 37.0 0.0 3.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 CAR30029.1 - 9.3e-08 30.9 0.0 2e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 HIM1 Epimerase PF01370.16 CAR30029.1 - 2.6e-05 23.7 0.0 6.9e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CAR30029.1 - 0.00012 22.3 0.0 0.00044 20.5 0.0 1.9 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF1471 PF07338.8 CAR30029.1 - 0.027 14.1 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) NmrA PF05368.8 CAR30029.1 - 0.058 12.6 0.0 0.9 8.7 0.0 2.2 2 1 0 2 2 2 0 NmrA-like family Globin PF00042.17 CAR30030.1 - 0.00076 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Globin Sugar_tr PF00083.19 CAR30031.1 - 2.7e-129 431.6 24.9 3.1e-129 431.4 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30031.1 - 9.7e-22 77.1 31.1 3.1e-18 65.6 7.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CAR30031.1 - 0.022 14.7 1.2 0.071 13.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) ATG2_CAD PF13329.1 CAR30032.1 - 2.9e-36 124.4 1.7 6.3e-36 123.3 0.2 2.4 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 CAR30032.1 - 5.4e-26 90.6 0.1 1.1e-25 89.5 0.1 1.6 1 0 0 1 1 1 1 ATG C terminal domain RhoGAP PF00620.22 CAR30033.1 - 6e-35 120.1 0.3 1e-33 116.0 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.17 CAR30033.1 - 1.9e-27 95.0 52.7 1.5e-12 47.3 4.5 4.5 4 0 0 4 4 4 4 LIM domain G6PD_C PF02781.11 CAR30034.1 - 2e-130 433.9 0.0 2.7e-130 433.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CAR30034.1 - 5e-64 215.8 0.0 1.5e-63 214.3 0.0 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Fe_hyd_lg_C PF02906.9 CAR30035.1 - 2.6e-67 227.0 0.0 3.5e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_S8 PF00082.17 CAR30036.1 - 6.3e-57 192.8 1.3 1.1e-56 192.0 0.9 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CAR30036.1 - 3e-25 87.8 1.1 6.9e-25 86.6 0.8 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF912 PF06024.7 CAR30036.1 - 0.0014 18.6 0.0 0.0043 17.0 0.0 1.8 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_M56 PF05569.6 CAR30036.1 - 0.21 10.5 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ytp1 PF10355.4 CAR30037.1 - 3.2e-80 269.2 10.4 4.7e-80 268.6 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) COX14 PF14880.1 CAR30037.1 - 0.047 13.3 1.4 0.69 9.5 0.0 2.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Ninjurin PF04923.7 CAR30037.1 - 0.29 10.8 1.9 4.2 7.1 0.0 3.2 3 1 0 3 3 3 0 Ninjurin Med16 PF11635.3 CAR30038.1 - 3.9e-163 544.2 4.8 4.6e-163 544.0 3.4 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF2304 PF10066.4 CAR30038.1 - 0.012 15.4 0.1 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Glycolytic PF00274.14 CAR30038.1 - 0.06 11.7 0.0 0.1 10.9 0.0 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Rpr2 PF04032.11 CAR30038.1 - 0.11 12.3 1.1 0.3 10.9 0.8 1.7 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DDE_Tnp_4 PF13359.1 CAR30039.1 - 1.1e-26 93.3 0.0 1.9e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 CAR30039.1 - 0.057 12.9 0.3 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Proteasome PF00227.21 CAR30040.1 - 1.1e-52 178.1 0.1 1.5e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CAR30040.1 - 2.3e-13 49.1 0.6 4e-13 48.4 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Bromodomain PF00439.20 CAR30041.1 - 7.4e-25 86.6 1.7 1.5e-24 85.6 1.2 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CAR30041.1 - 3e-09 36.9 0.2 6.4e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CAR30041.1 - 6e-09 35.8 0.1 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CAR30041.1 - 0.00082 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR30041.1 - 0.12 12.1 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein ThiF PF00899.16 CAR30042.1 - 7.2e-32 110.0 0.0 1.4e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CAR30042.1 - 0.0059 16.7 0.0 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CAR30042.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NMD3 PF04981.8 CAR30043.1 - 2e-75 252.9 3.0 2e-75 252.9 2.1 1.5 2 0 0 2 2 2 1 NMD3 family HypA PF01155.14 CAR30043.1 - 0.11 12.1 3.9 4.1 7.1 0.6 2.5 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family NinF PF05810.7 CAR30043.1 - 0.27 11.0 3.9 6.5 6.6 0.1 3.3 3 0 0 3 3 3 0 NinF protein NOA36 PF06524.7 CAR30043.1 - 0.32 10.2 4.0 4.6 6.3 2.1 2.2 2 0 0 2 2 2 0 NOA36 protein FYVE PF01363.16 CAR30043.1 - 0.85 9.5 6.6 0.71 9.8 2.2 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF2702 PF10863.3 CAR30044.1 - 1e-41 141.9 8.1 1.5e-41 141.4 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2702) DEAD PF00270.24 CAR30045.1 - 4e-42 143.5 0.4 1.1e-40 138.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30045.1 - 8.8e-28 95.9 0.2 1.9e-27 94.8 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR30045.1 - 0.0092 15.8 0.1 0.042 13.6 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit GTP1_OBG PF01018.17 CAR30046.1 - 6.1e-34 116.9 1.4 5.7e-24 84.5 0.8 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CAR30046.1 - 2.7e-20 72.4 0.0 4.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR30046.1 - 7.4e-12 44.8 0.0 1.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 CAR30046.1 - 1.8e-09 37.0 0.0 7.3e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR30046.1 - 7.1e-05 22.3 0.1 0.0089 15.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CAR30046.1 - 8.2e-05 23.0 0.0 0.00018 21.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 CAR30046.1 - 0.0045 17.8 0.1 0.089 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CAR30046.1 - 0.009 14.8 0.0 0.35 9.6 0.0 2.2 2 0 0 2 2 2 1 ArgK protein Ras PF00071.17 CAR30046.1 - 0.03 13.7 0.0 0.097 12.0 0.0 1.8 2 0 0 2 2 2 0 Ras family SRPRB PF09439.5 CAR30046.1 - 0.059 12.5 0.0 0.36 10.0 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CAR30046.1 - 0.08 12.7 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family THP2 PF09432.5 CAR30047.1 - 4.5e-27 94.4 3.4 4.5e-27 94.4 2.4 2.2 2 2 0 2 2 2 1 Tho complex subunit THP2 SAM_2 PF07647.12 CAR30047.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TBPIP PF07106.8 CAR30047.1 - 0.57 9.7 6.2 0.12 11.9 0.3 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APC8 PF04049.8 CAR30048.1 - 4.7e-39 133.3 5.3 1.2e-38 132.1 3.7 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 CAR30048.1 - 1.3e-24 84.7 16.2 1.6e-05 24.2 0.0 8.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 CAR30048.1 - 6.8e-22 76.9 12.4 3.5e-09 36.1 0.1 6.6 5 1 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 CAR30048.1 - 4.6e-21 72.9 19.9 0.00046 19.9 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 CAR30048.1 - 8.9e-16 56.4 19.5 0.00037 20.0 0.0 8.3 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 CAR30048.1 - 3e-12 46.2 16.8 0.0031 17.4 0.2 5.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CAR30048.1 - 7.3e-12 44.8 0.0 0.0029 18.0 0.0 6.1 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CAR30048.1 - 2.3e-10 39.4 5.8 0.0058 16.3 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CAR30048.1 - 1.2e-09 37.6 4.0 0.0011 19.0 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR30048.1 - 1.8e-09 38.0 0.1 2.2e-05 25.0 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 CAR30048.1 - 0.00031 19.6 0.0 0.0013 17.5 0.0 1.9 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.1 CAR30048.1 - 0.002 17.2 6.7 0.056 12.5 0.2 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR30048.1 - 0.0021 17.8 0.6 3.5 7.5 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CAR30048.1 - 0.015 15.3 22.5 0.48 10.6 0.7 5.3 2 1 5 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CAR30048.1 - 0.029 14.7 2.7 4.5 7.6 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 CAR30048.1 - 0.036 13.9 0.6 16 5.4 0.0 3.2 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain PROCN PF08083.6 CAR30049.1 - 1.1e-216 719.0 10.7 1.7e-216 718.4 7.4 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CAR30049.1 - 1.4e-120 400.8 0.8 2.4e-120 400.0 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CAR30049.1 - 1.7e-88 294.0 0.4 3.3e-88 293.0 0.3 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CAR30049.1 - 7.5e-76 252.9 1.8 1.7e-75 251.7 1.1 1.8 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CAR30049.1 - 1.8e-64 215.4 0.0 3.8e-64 214.3 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 CAR30049.1 - 2.6e-46 156.3 0.1 8.8e-46 154.6 0.1 2.0 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 CAR30049.1 - 3.6e-44 148.5 0.2 9.8e-44 147.1 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 CAR30049.1 - 0.0033 17.1 0.1 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Dna2 PF08696.6 CAR30051.1 - 3.6e-59 199.5 0.0 7.3e-59 198.5 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 CAR30051.1 - 4.8e-51 172.9 0.0 1e-50 171.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CAR30051.1 - 1.6e-35 122.7 0.0 1.6e-18 67.1 0.0 3.0 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 CAR30051.1 - 1.3e-11 44.5 0.0 2.3e-10 40.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 CAR30051.1 - 5.5e-08 32.6 0.6 0.035 13.6 0.1 4.1 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CAR30051.1 - 1.4e-07 31.1 0.0 3.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CAR30051.1 - 0.00078 19.5 0.3 0.088 12.9 0.0 3.1 3 1 0 3 3 2 1 AAA domain Helicase_RecD PF05127.9 CAR30051.1 - 0.0009 18.9 0.0 0.0027 17.3 0.0 1.8 1 0 0 1 1 1 1 Helicase MobB PF03205.9 CAR30051.1 - 0.0022 17.7 0.2 0.0069 16.0 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CAR30051.1 - 0.0036 17.2 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 CAR30051.1 - 0.0038 16.2 0.0 0.0088 15.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CAR30051.1 - 0.006 16.3 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 CAR30051.1 - 0.0075 16.5 0.3 0.039 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CAR30051.1 - 0.0086 15.5 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 CAR30051.1 - 0.0098 15.2 0.0 0.025 13.8 0.0 1.8 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 CAR30051.1 - 0.011 14.7 0.0 0.35 9.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase NTPase_1 PF03266.10 CAR30051.1 - 0.011 15.4 1.2 0.34 10.6 0.2 2.6 2 0 0 2 2 2 0 NTPase CbiA PF01656.18 CAR30051.1 - 0.031 13.6 0.0 0.097 12.0 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.2 CAR30051.1 - 0.046 13.1 0.3 0.18 11.2 0.0 2.1 3 0 0 3 3 2 0 AAA-like domain AAA PF00004.24 CAR30051.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CAR30051.1 - 0.074 13.8 0.0 0.37 11.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CAR30051.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.10 CAR30051.1 - 0.084 12.6 0.1 0.084 12.6 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 CAR30051.1 - 0.095 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CAR30051.1 - 0.19 10.4 0.3 0.48 9.1 0.0 1.7 2 0 0 2 2 2 0 ArgK protein RRM_1 PF00076.17 CAR30052.1 - 2.6e-31 107.0 0.1 5.2e-15 54.8 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR30052.1 - 1.2e-20 73.2 0.0 5.2e-10 39.1 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR30052.1 - 1.9e-12 46.8 0.0 0.00012 21.8 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb6 PF01192.17 CAR30052.1 - 0.17 11.6 0.0 0.68 9.7 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb6 HSF_DNA-bind PF00447.12 CAR30053.1 - 1e-23 83.4 0.0 2.3e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Glucosamine_iso PF01182.15 CAR30054.1 - 4.4e-51 173.4 0.0 5.7e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MPC PF03650.8 CAR30055.1 - 2.1e-47 160.0 0.1 2.6e-47 159.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ATP-grasp_2 PF08442.5 CAR30056.1 - 7.9e-74 247.4 2.0 1.4e-73 246.6 1.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CAR30056.1 - 5.6e-26 90.9 2.6 5.3e-25 87.7 0.0 3.2 3 1 1 4 4 4 1 CoA-ligase ATP-grasp_5 PF13549.1 CAR30056.1 - 3.6e-07 29.6 0.6 5.7e-07 28.9 0.4 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CAR30056.1 - 0.00063 19.3 0.7 0.002 17.7 0.2 2.0 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain zf-ZPR1 PF03367.8 CAR30056.1 - 0.023 13.8 0.9 0.049 12.7 0.2 1.8 2 0 0 2 2 2 0 ZPR1 zinc-finger domain SDA1 PF05285.7 CAR30057.1 - 1.3e-93 313.8 30.5 1.3e-93 313.8 21.2 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 CAR30057.1 - 7.4e-22 77.3 0.0 1.9e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain TFIIB PF00382.14 CAR30058.1 - 4.2e-56 186.6 1.0 7.4e-28 96.1 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CAR30058.1 - 1.3e-27 95.8 0.5 1.3e-27 95.8 0.3 2.7 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CAR30058.1 - 7.7e-11 41.1 3.4 1.4e-10 40.2 2.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 CAR30058.1 - 9.6e-07 28.4 0.4 0.0082 15.7 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain A2L_zn_ribbon PF08792.5 CAR30058.1 - 1.1 8.8 5.3 3 7.4 3.7 1.8 1 1 0 1 1 1 0 A2L zinc ribbon domain CPDase PF07823.6 CAR30059.1 - 5e-62 208.8 0.0 5.5e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CAR30059.1 - 0.0025 17.5 0.0 0.0089 15.7 0.0 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF3722 PF12519.3 CAR30059.1 - 0.085 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) Fungal_trans_2 PF11951.3 CAR30060.1 - 2.2e-79 266.8 0.3 3e-79 266.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR30060.1 - 4.6e-07 29.6 10.9 7.7e-07 28.9 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSG PF02349.10 CAR30060.1 - 0.12 12.3 7.0 0.26 11.2 4.8 1.5 1 0 0 1 1 1 0 Major surface glycoprotein Dickkopf_N PF04706.7 CAR30060.1 - 2.6 8.2 10.5 6 7.1 7.3 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region PRELI PF04707.9 CAR30061.1 - 4.8e-43 146.4 0.1 5.7e-43 146.1 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Chorion_3 PF05387.6 CAR30062.1 - 0.84 9.0 11.8 0.03 13.7 4.2 1.6 2 0 0 2 2 2 0 Chorion family 3 Hira PF07569.6 CAR30062.1 - 9.7 5.3 10.6 6.3 5.9 5.9 1.7 1 1 1 2 2 2 0 TUP1-like enhancer of split NMT PF01233.14 CAR30063.1 - 2.1e-82 274.5 0.5 8.1e-82 272.6 0.1 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CAR30063.1 - 8.3e-76 253.6 0.3 1.3e-75 252.9 0.2 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CAR30063.1 - 0.0012 18.6 0.0 0.043 13.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CAR30063.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AF1Q PF15017.1 CAR30063.1 - 0.23 11.3 3.4 0.63 9.9 2.4 1.8 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator WD40 PF00400.27 CAR30064.1 - 2.7e-19 68.2 9.7 1.7e-07 30.8 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CAR30064.1 - 0.0024 16.0 1.2 0.017 13.2 0.3 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nop PF01798.13 CAR30066.1 - 4.2e-61 204.6 0.0 7.6e-61 203.8 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CAR30066.1 - 4.6e-27 93.5 0.2 8.9e-27 92.6 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CAR30066.1 - 1.5e-23 82.7 0.2 1.5e-23 82.7 0.1 2.6 2 1 0 2 2 2 1 NOP5NT (NUC127) domain RNase_H2-Ydr279 PF09468.5 CAR30066.1 - 0.0021 17.3 14.0 0.0038 16.4 9.7 1.6 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 CAR30066.1 - 0.27 11.1 17.3 0.38 10.6 12.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 CAR30066.1 - 0.3 10.4 28.1 0.45 9.8 19.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 CAR30066.1 - 2.1 6.2 21.0 2.7 5.8 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CAR30066.1 - 9.6 5.9 13.9 16 5.2 9.6 1.4 1 0 0 1 1 1 0 DDHD domain POC1 PF10450.4 CAR30067.1 - 2e-50 171.0 0.0 2.5e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 POC1 chaperone Prefoldin_2 PF01920.15 CAR30068.1 - 1.8e-20 72.6 12.2 2.1e-20 72.4 8.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4201 PF13870.1 CAR30068.1 - 0.0032 16.9 9.4 0.0053 16.2 2.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Med9 PF07544.8 CAR30068.1 - 0.024 14.3 0.5 0.024 14.3 0.4 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1732 PF08340.6 CAR30068.1 - 0.052 13.3 2.6 0.095 12.5 1.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) DUF1192 PF06698.6 CAR30068.1 - 0.063 13.0 0.2 0.063 13.0 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Spc24 PF08286.6 CAR30068.1 - 0.7 9.5 10.7 0.41 10.3 1.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DMPK_coil PF08826.5 CAR30068.1 - 1 9.3 8.2 5.3 7.0 0.3 2.8 2 1 1 3 3 3 0 DMPK coiled coil domain like Fib_alpha PF08702.5 CAR30068.1 - 2.4 8.2 6.7 3 7.9 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Med4 PF10018.4 CAR30068.1 - 3.2 7.1 7.2 0.56 9.5 1.3 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 COQ9 PF08511.6 CAR30069.1 - 1.8e-19 69.0 0.1 3.9e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 COQ9 ADH_N PF08240.7 CAR30070.1 - 2.2e-27 94.9 3.5 2.2e-27 94.9 2.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CAR30070.1 - 5.1e-19 68.1 0.4 8.9e-19 67.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CAR30070.1 - 0.029 13.5 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 CAR30070.1 - 0.05 13.1 1.5 0.09 12.3 1.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.9 CAR30070.1 - 0.051 12.9 0.2 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-RanBP PF00641.13 CAR30071.1 - 3.9e-21 73.8 13.1 4.8e-11 41.5 1.7 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 CAR30071.1 - 1.6e-09 37.2 0.0 0.00046 19.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR30071.1 - 0.00039 20.3 0.0 0.0061 16.5 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 CAR30071.1 - 0.052 13.3 8.8 1.1 9.1 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon GCC2_GCC3 PF07699.8 CAR30071.1 - 1.1 8.9 8.7 0.16 11.6 0.8 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 AAA_18 PF13238.1 CAR30072.1 - 5.2e-28 97.9 0.7 8.1e-28 97.3 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR30072.1 - 1.2e-13 51.8 0.7 3.2e-13 50.5 0.5 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR30072.1 - 8.2e-05 21.7 0.0 0.00025 20.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 CAR30072.1 - 0.00014 21.8 0.0 0.00021 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CAR30072.1 - 0.00038 20.6 0.0 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CAR30072.1 - 0.00072 19.5 0.0 0.002 18.0 0.0 1.8 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 CAR30072.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 CAR30072.1 - 0.0051 16.6 0.1 0.75 9.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR30072.1 - 0.0052 16.9 0.2 0.017 15.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 CAR30072.1 - 0.015 14.7 0.1 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase KTI12 PF08433.5 CAR30072.1 - 0.015 14.4 0.0 0.035 13.3 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 CAR30072.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CAR30072.1 - 0.022 14.4 0.0 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CAR30072.1 - 0.024 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 CAR30072.1 - 0.028 14.1 0.0 0.05 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CAR30072.1 - 0.028 14.1 0.0 0.067 12.8 0.0 1.6 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.13 CAR30072.1 - 0.037 13.5 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase GvpD PF07088.6 CAR30072.1 - 0.046 12.0 0.0 0.075 11.3 0.0 1.3 1 1 0 1 1 1 0 GvpD gas vesicle protein PRK PF00485.13 CAR30072.1 - 0.083 12.4 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 CAR30072.1 - 0.096 12.1 0.0 0.29 10.5 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain NOT2_3_5 PF04153.13 CAR30073.1 - 8.4e-35 119.5 0.6 1e-34 119.3 0.4 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family zf-Mss51 PF13824.1 CAR30074.1 - 1.5e-18 66.3 0.7 4.2e-18 64.9 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CAR30074.1 - 0.0019 17.7 0.1 0.0049 16.3 0.1 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF1713 PF08213.6 CAR30075.1 - 6.5e-13 48.0 22.6 1e-12 47.4 15.7 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) DUF3538 PF12057.3 CAR30075.1 - 0.11 12.1 0.1 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) Heme_oxygenase PF01126.15 CAR30076.1 - 7e-15 55.1 1.2 2.3e-14 53.4 0.8 1.9 1 1 0 1 1 1 1 Heme oxygenase DNA_ligase_A_M PF01068.16 CAR30077.1 - 6.2e-57 192.2 0.0 9.4e-57 191.6 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CAR30077.1 - 6.6e-52 175.8 0.1 6.6e-52 175.8 0.1 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CAR30077.1 - 3.1e-25 88.3 0.0 7e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CAR30077.1 - 0.045 13.4 0.4 5.8 6.6 0.0 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain ENTH PF01417.15 CAR30078.1 - 2.6e-43 146.8 0.0 6.5e-43 145.5 0.0 1.7 1 0 0 1 1 1 1 ENTH domain Herpes_UL87 PF03043.9 CAR30078.1 - 9.3 4.5 13.0 12 4.1 9.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family CENP-X PF09415.5 CAR30079.1 - 4e-26 90.6 0.2 4.5e-26 90.4 0.1 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Dynactin_p62 PF05502.8 CAR30080.1 - 1.5e-15 56.9 22.7 1e-07 31.1 12.8 2.2 1 1 1 2 2 2 2 Dynactin p62 family zf-Mss51 PF13824.1 CAR30080.1 - 0.18 11.6 10.3 8.9 6.2 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2296 PF10058.4 CAR30080.1 - 0.68 9.7 14.6 1.6 8.5 0.0 3.7 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Prok-RING_2 PF14445.1 CAR30080.1 - 3.6 7.5 11.3 1 9.3 4.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Sel1 PF08238.7 CAR30081.1 - 1.4e-18 66.8 17.0 0.00025 21.5 0.0 9.5 10 0 0 10 10 10 6 Sel1 repeat TPR_11 PF13414.1 CAR30081.1 - 0.00054 19.5 6.4 0.55 9.9 0.0 4.9 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 CAR30081.1 - 0.15 11.8 8.7 9 6.3 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 CAR30081.1 - 0.7 10.6 12.2 0.32 11.7 0.2 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 CAR30081.1 - 1.3 8.7 8.4 0.41 10.3 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 CAR30082.1 - 9.1e-43 142.6 15.8 4.2e-10 39.1 0.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CAR30082.1 - 0.0031 17.2 5.5 0.0098 15.6 0.6 3.1 1 1 3 4 4 4 1 Transcription factor IIIC subunit delta N-term Kelch_6 PF13964.1 CAR30082.1 - 0.0084 16.2 0.3 7.1 6.9 0.0 3.1 3 0 0 3 3 3 2 Kelch motif YmzC PF14157.1 CAR30082.1 - 0.0089 15.8 0.1 0.47 10.3 0.0 3.1 4 0 0 4 4 4 1 YmzC-like protein PNP_UDP_1 PF01048.15 CAR30083.1 - 3.2e-48 163.7 0.0 3.7e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DEAD PF00270.24 CAR30084.1 - 1.1e-40 138.9 0.0 1.7e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30084.1 - 1.5e-25 88.8 0.1 3.1e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CAR30084.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain PAT1 PF09770.4 CAR30084.1 - 7 4.7 20.5 9.7 4.2 14.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 CAR30085.1 - 2.3e-63 213.7 0.0 3.1e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30085.1 - 6.2e-38 130.3 0.0 9.2e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30085.1 - 0.00066 18.7 0.0 0.0014 17.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.27 CAR30087.1 - 2.7e-10 39.7 4.0 0.0026 17.5 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 CAR30089.1 - 2.2e-15 56.1 0.6 4.7e-15 55.0 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR30089.1 - 1e-05 25.2 9.1 2e-05 24.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.18 CAR30090.1 - 2.6e-44 149.8 0.5 4.5e-44 149.0 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CAR30090.1 - 6.5e-28 97.0 0.2 2.2e-27 95.3 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sas10 PF09368.5 CAR30091.1 - 2e-28 98.3 11.9 5.9e-28 96.8 8.3 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CAR30091.1 - 2.1e-10 40.6 0.2 2.1e-10 40.6 0.2 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family RNA_pol_Rpc4 PF05132.9 CAR30092.1 - 4.1e-33 114.1 1.3 4.1e-33 114.1 0.9 2.7 3 0 0 3 3 3 1 RNA polymerase III RPC4 APG9 PF04109.11 CAR30093.1 - 4.3e-167 555.6 7.5 5.9e-167 555.2 5.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Nop14 PF04147.7 CAR30094.1 - 9e-219 728.5 69.6 1.5e-123 413.5 10.8 2.0 1 1 1 2 2 2 2 Nop14-like family PCI PF01399.22 CAR30095.1 - 3.8e-22 78.5 2.9 7.6e-22 77.6 0.0 2.9 3 1 0 3 3 3 1 PCI domain Img2 PF05046.9 CAR30095.1 - 0.027 14.6 0.3 0.16 12.2 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Ribosomal_L18e PF00828.14 CAR30095.1 - 0.1 12.9 1.0 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L18e/L15 NPV_P10 PF05531.7 CAR30095.1 - 6.1 7.1 8.0 0.79 10.0 1.2 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2216 PF10226.4 CAR30096.1 - 0.0032 17.0 1.9 0.0093 15.4 0.6 2.0 2 0 0 2 2 2 1 Uncharacterized conserved proteins (DUF2216) Borrelia_REV PF03978.8 CAR30096.1 - 0.0033 17.1 5.2 0.34 10.6 0.2 2.1 2 0 0 2 2 2 2 Borrelia burgdorferi REV protein bZIP_1 PF00170.16 CAR30096.1 - 0.011 15.6 0.8 0.011 15.6 0.6 3.1 2 2 1 3 3 3 0 bZIP transcription factor COMP PF11598.3 CAR30096.1 - 0.049 13.7 0.6 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein EF_TS PF00889.14 CAR30096.1 - 0.059 12.6 1.1 0.094 12.0 0.7 1.5 1 1 0 1 1 1 0 Elongation factor TS DUF1465 PF07323.7 CAR30096.1 - 0.13 11.8 1.5 0.16 11.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DUF948 PF06103.6 CAR30096.1 - 0.19 11.6 3.4 2.5 8.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec8_exocyst PF04048.9 CAR30096.1 - 0.2 11.2 4.9 0.059 13.0 0.6 1.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF972 PF06156.8 CAR30096.1 - 0.38 11.1 8.4 0.85 9.9 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 CAR30096.1 - 0.42 10.7 5.2 0.37 10.8 0.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GPO PF05929.6 CAR30096.1 - 1.1 8.4 4.7 0.32 10.1 0.7 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Cauli_AT PF03233.8 CAR30096.1 - 1.7 8.2 8.4 1.8 8.2 1.2 2.2 2 0 0 2 2 2 0 Aphid transmission protein DivIC PF04977.10 CAR30096.1 - 2.7 7.5 10.2 0.23 10.9 1.3 2.7 2 2 1 3 3 3 0 Septum formation initiator IncA PF04156.9 CAR30096.1 - 6.8 6.2 9.9 1.1 8.8 1.4 2.2 2 0 0 2 2 2 0 IncA protein DUF2013 PF09431.5 CAR30097.1 - 1.5e-43 147.8 14.0 3.7e-43 146.6 9.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) HIGH_NTase1 PF05636.6 CAR30097.1 - 0.011 14.8 2.3 0.017 14.1 1.6 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase BAG PF02179.11 CAR30097.1 - 0.03 14.4 0.4 0.069 13.2 0.3 1.6 1 0 0 1 1 1 0 BAG domain Tubulin PF00091.20 CAR30098.1 - 3e-68 229.8 0.1 4.7e-68 229.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CAR30098.1 - 3.1e-23 82.1 0.1 6.6e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CAR30098.1 - 4.7e-07 29.8 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CAR30098.1 - 0.0095 15.4 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Methyltransf_2 PF00891.13 CAR30098.1 - 0.064 12.4 0.1 0.17 11.0 0.1 1.6 1 0 0 1 1 1 0 O-methyltransferase Coatomer_WDAD PF04053.9 CAR30099.1 - 8.9e-130 433.4 4.3 1.3e-129 432.8 3.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CAR30099.1 - 4.2e-59 200.1 0.0 6.7e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CAR30099.1 - 7e-54 177.9 17.9 9.7e-11 41.1 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CAR30099.1 - 2.7e-05 22.5 6.8 0.31 9.1 0.0 3.7 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Glyco_hydro_16 PF00722.16 CAR30100.1 - 2.2e-40 137.9 0.0 3.4e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 CAR30100.1 - 0.075 13.0 11.7 0.16 11.9 8.1 1.5 1 0 0 1 1 1 0 Chitin recognition protein WAP PF00095.16 CAR30100.1 - 6.1 6.9 14.6 0.26 11.2 6.1 1.8 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ferric_reduct PF01794.14 CAR30101.1 - 1e-20 74.0 15.4 1.1e-20 73.9 8.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAR30101.1 - 3.4e-18 65.4 0.0 6.4e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CAR30101.1 - 1.9e-15 57.1 0.0 4.5e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 CAR30101.1 - 0.0042 17.1 0.7 0.0042 17.1 0.5 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4405) NAD_binding_1 PF00175.16 CAR30101.1 - 0.039 14.5 0.0 0.31 11.6 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain CFEM PF05730.6 CAR30101.1 - 0.19 11.5 0.6 0.39 10.5 0.4 1.5 1 0 0 1 1 1 0 CFEM domain D123 PF07065.9 CAR30102.1 - 1.4e-106 355.9 0.8 1.7e-106 355.6 0.6 1.1 1 0 0 1 1 1 1 D123 Cpn60_TCP1 PF00118.19 CAR30103.1 - 4e-136 454.4 13.2 4.6e-136 454.2 9.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 CAR30103.1 - 0.024 13.9 0.5 0.78 8.9 0.1 2.7 2 0 0 2 2 2 0 DeoC/LacD family aldolase CDP-OH_P_transf PF01066.16 CAR30104.1 - 1.6e-16 60.4 3.4 2.5e-16 59.8 2.4 1.4 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4052 PF13261.1 CAR30104.1 - 0.033 13.6 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4052) BPL_N PF09825.4 CAR30105.1 - 4.6e-131 436.9 0.0 5.8e-131 436.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CAR30105.1 - 8.7e-14 51.6 0.0 1.2e-12 47.9 0.0 2.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CAR30105.1 - 5.5e-12 45.1 0.1 1.3e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain RNA_pol_Rpb1_1 PF04997.7 CAR30106.1 - 2.5e-120 401.7 0.0 4.9e-120 400.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CAR30106.1 - 7.1e-108 360.0 0.1 1.2e-107 359.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CAR30106.1 - 8.8e-73 243.7 0.0 2e-72 242.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CAR30106.1 - 2.7e-64 216.3 2.4 2.7e-64 216.3 1.7 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CAR30106.1 - 6.7e-47 159.1 0.0 1.9e-46 157.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CAR30106.1 - 1.9e-46 157.1 4.0 4.3e-46 155.9 2.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CAR30106.1 - 1.4e-35 121.3 0.1 3.4e-35 120.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CAR30106.1 - 1.5e-13 49.6 308.4 0.038 14.1 9.1 15.4 8 1 2 16 16 16 13 RNA polymerase Rpb1 C-terminal repeat Pro_isomerase PF00160.16 CAR30107.1 - 3e-43 147.7 0.1 4.8e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CAR30107.1 - 7.6e-13 47.9 0.4 1.5e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAR30107.1 - 1.3e-11 43.5 0.0 7.6e-06 25.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR30107.1 - 6.4e-10 38.1 0.0 0.00098 18.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CAR30107.1 - 2e-05 24.7 0.6 0.5 10.9 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR30107.1 - 2.8e-05 23.9 0.3 0.0054 16.6 0.3 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR30107.1 - 0.00019 20.9 0.1 0.15 11.9 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR30107.1 - 0.0031 17.3 0.0 0.021 14.6 0.1 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR30107.1 - 0.0031 17.6 4.6 0.43 10.7 0.6 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CAR30107.1 - 0.019 15.6 0.2 0.056 14.1 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 CAR30107.1 - 0.026 14.6 0.2 0.68 10.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PUL PF08324.6 CAR30107.1 - 0.055 12.2 0.9 0.087 11.6 0.5 1.4 1 1 0 1 1 1 0 PUL domain Scm3 PF10384.4 CAR30108.1 - 1.9e-23 81.7 0.3 8.8e-23 79.5 0.2 2.1 2 0 0 2 2 2 1 Centromere protein Scm3 CHCH PF06747.8 CAR30109.1 - 0.00013 21.7 3.8 0.00013 21.7 2.7 2.1 2 0 0 2 2 2 1 CHCH domain DB PF01682.14 CAR30109.1 - 0.06 13.3 0.7 0.077 13.0 0.5 1.2 1 0 0 1 1 1 0 DB module CbiK PF06180.6 CAR30109.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Sec31 PF11549.3 CAR30110.1 - 4.5e-26 90.2 5.7 2.4e-25 87.9 3.9 2.3 1 0 0 1 1 1 1 Protein transport protein SEC31 WD40 PF00400.27 CAR30110.1 - 7.8e-18 63.6 8.3 0.0024 17.6 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 CAR30110.1 - 5.6e-07 29.4 2.6 1.2e-06 28.3 0.0 2.8 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 CAR30110.1 - 0.0012 18.6 0.4 0.002 17.9 0.3 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 CAR30110.1 - 0.007 16.1 0.1 0.023 14.5 0.1 1.9 1 1 0 1 1 1 1 Prp18 domain Sugar_tr PF00083.19 CAR30111.1 - 3.9e-120 401.4 30.8 4.7e-120 401.2 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30111.1 - 1.7e-17 63.1 37.8 8.7e-14 50.9 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.8 CAR30111.1 - 0.054 13.5 0.1 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2456 PF10445.4 CAR30111.1 - 0.72 9.7 6.0 0.066 13.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Prenyltransf PF01255.14 CAR30112.1 - 1.1e-05 24.6 0.0 5.3e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF1003 PF06210.6 CAR30112.1 - 0.058 13.3 0.4 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Arf PF00025.16 CAR30113.1 - 4.1e-79 263.8 0.0 4.8e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAR30113.1 - 6e-15 54.9 0.0 7.4e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR30113.1 - 7.5e-14 51.4 0.0 8.2e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAR30113.1 - 5.3e-13 48.4 1.1 4.3e-10 38.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAR30113.1 - 4.5e-12 45.6 0.0 5.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR30113.1 - 3.8e-11 43.5 0.0 5.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR30113.1 - 3.7e-06 26.8 0.1 6.6e-06 26.0 0.0 1.5 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR30113.1 - 0.0048 16.3 0.1 0.023 14.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CAR30113.1 - 0.0055 16.1 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CAR30113.1 - 0.0082 16.0 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 CAR30113.1 - 0.012 15.0 0.1 3.7 6.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 CAR30113.1 - 0.015 14.2 1.1 0.83 8.5 0.1 2.0 1 1 1 2 2 2 0 KAP family P-loop domain NACHT PF05729.7 CAR30113.1 - 0.016 14.8 0.5 2 8.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 CAR30113.1 - 0.091 12.2 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 CAR30113.1 - 0.11 11.5 0.8 0.36 9.8 0.5 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.12 CAR30113.1 - 0.12 11.6 1.1 0.91 8.8 0.2 2.0 2 0 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.22 CAR30113.1 - 0.15 12.3 0.3 0.29 11.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 CAR30113.1 - 0.24 12.2 0.8 0.57 11.0 0.5 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 CAR30114.1 - 1.2e-79 265.6 0.0 1.4e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CAR30114.1 - 4.7e-15 55.2 0.0 5.7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR30114.1 - 6.6e-14 51.6 0.0 7.1e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CAR30114.1 - 1.9e-12 46.5 1.1 1.2e-09 37.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CAR30114.1 - 7.8e-12 44.8 0.0 9.4e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CAR30114.1 - 3.4e-11 43.6 0.0 4.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR30114.1 - 5.5e-06 26.3 0.0 7.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR30114.1 - 0.0047 16.3 0.1 0.023 14.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CAR30114.1 - 0.0052 16.2 0.2 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CAR30114.1 - 0.0086 15.9 0.2 0.013 15.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CAR30114.1 - 0.025 14.2 0.6 3 7.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CAR30114.1 - 0.026 13.9 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.13 CAR30114.1 - 0.062 12.3 1.2 0.32 10.0 0.8 1.9 1 1 0 1 1 1 0 6-phosphofructo-2-kinase PduV-EutP PF10662.4 CAR30114.1 - 0.094 12.2 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CAR30114.1 - 0.17 12.1 0.3 0.33 11.2 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 CAR30114.1 - 0.2 12.5 0.5 0.48 11.2 0.4 1.7 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CAR30114.1 - 0.22 10.9 1.1 0.91 8.8 0.2 1.9 2 0 0 2 2 2 0 Thymidylate kinase Ribosomal_L29 PF00831.18 CAR30115.1 - 9.1e-17 60.4 2.3 9.1e-17 60.4 1.6 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein Annexin PF00191.15 CAR30115.1 - 0.053 13.4 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Annexin AA_permease_N PF08403.5 CAR30115.1 - 0.074 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF4404 PF14357.1 CAR30115.1 - 0.15 12.4 2.1 0.35 11.2 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) MRP-L47 PF06984.8 CAR30115.1 - 0.28 11.1 1.9 0.44 10.4 0.4 2.0 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ufd2P_core PF10408.4 CAR30116.1 - 1.4e-193 644.6 10.4 2e-193 644.1 7.2 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CAR30116.1 - 4.9e-29 100.0 0.9 1.3e-28 98.7 0.7 1.8 1 0 0 1 1 1 1 U-box domain R3H PF01424.17 CAR30117.1 - 7.2e-10 38.4 0.0 1.8e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 R3H domain Rho_GDI PF02115.12 CAR30118.1 - 1.5e-66 223.6 2.5 1.6e-66 223.5 1.8 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor OHCU_decarbox PF09349.5 CAR30119.1 - 1.3e-35 123.0 0.2 1.6e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase WAPL PF07814.8 CAR30119.1 - 0.029 13.1 0.2 0.035 12.8 0.1 1.1 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin HWE_HK PF07536.9 CAR30119.1 - 0.07 13.5 0.1 0.16 12.3 0.0 1.7 2 1 0 2 2 2 0 HWE histidine kinase PMC2NT PF08066.7 CAR30119.1 - 0.082 13.2 0.3 0.44 10.8 0.1 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Metallophos PF00149.23 CAR30120.1 - 3.8e-39 134.1 0.3 4.8e-39 133.8 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_ab PF00006.20 CAR30122.1 - 4.2e-123 408.8 0.0 5.9e-123 408.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CAR30122.1 - 3.6e-20 72.5 0.1 6.8e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CAR30122.1 - 7.2e-16 58.1 2.2 1.9e-15 56.8 1.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 CAR30122.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Imm31 PF15595.1 CAR30122.1 - 0.087 12.5 0.2 3.3 7.5 0.1 2.5 2 0 0 2 2 2 0 Immunity protein 31 Mit_KHE1 PF10173.4 CAR30123.1 - 4.4e-59 199.4 3.3 5.6e-59 199.1 2.3 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Anoctamin PF04547.7 CAR30124.1 - 0.017 13.7 1.3 0.036 12.7 0.0 1.9 2 0 0 2 2 2 0 Calcium-activated chloride channel MARVEL PF01284.18 CAR30124.1 - 0.12 12.1 2.9 0.2 11.4 2.0 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF3671 PF12420.3 CAR30124.1 - 0.39 10.7 2.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function Cullin PF00888.17 CAR30125.1 - 2.4e-154 515.1 9.5 3e-154 514.7 6.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CAR30125.1 - 1.2e-24 85.9 0.3 4e-24 84.2 0.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Apc4 PF12896.2 CAR30125.1 - 0.0081 15.4 1.8 0.014 14.7 0.5 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 Penicillinase_R PF03965.11 CAR30125.1 - 0.1 12.6 2.2 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Penicillinase repressor HMGL-like PF00682.14 CAR30126.1 - 1.8e-73 247.1 0.3 2.9e-73 246.4 0.2 1.4 1 0 0 1 1 1 1 HMGL-like ADP_PFK_GK PF04587.10 CAR30126.1 - 0.0015 16.8 0.0 0.0023 16.2 0.0 1.2 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region WD40 PF00400.27 CAR30127.1 - 1.7e-11 43.5 1.2 0.0025 17.6 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat IATP PF04568.7 CAR30128.1 - 2.5e-20 72.3 1.1 2.8e-20 72.1 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP IncA PF04156.9 CAR30128.1 - 0.0075 15.8 0.6 0.0075 15.8 0.4 1.1 1 0 0 1 1 1 1 IncA protein Fib_alpha PF08702.5 CAR30128.1 - 0.078 13.0 1.0 0.11 12.6 0.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PspB PF06667.7 CAR30128.1 - 0.093 12.6 2.2 0.14 12.1 1.5 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF3573 PF12097.3 CAR30128.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) CENP-Q PF13094.1 CAR30128.1 - 0.16 11.9 5.2 0.21 11.5 3.6 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DIRP PF06584.8 CAR30128.1 - 0.24 11.2 2.4 0.36 10.7 1.7 1.3 1 0 0 1 1 1 0 DIRP DUF1903 PF08991.5 CAR30129.1 - 6.9e-27 93.4 7.9 7.9e-27 93.2 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CAR30129.1 - 0.0069 16.2 5.1 0.0069 16.2 3.5 1.5 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 CAR30129.1 - 0.085 12.6 5.1 0.23 11.2 0.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF724 PF05266.9 CAR30130.1 - 0.06 12.9 2.8 0.08 12.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) cwf21 PF08312.7 CAR30130.1 - 0.097 12.5 4.6 4.1 7.3 0.1 3.3 1 1 2 3 3 3 0 cwf21 domain Ribosomal_L36e PF01158.13 CAR30131.1 - 4.1e-37 126.0 3.7 4.5e-37 125.9 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Ribosomal_L28 PF00830.14 CAR30132.1 - 2.2e-20 72.2 0.7 3.5e-20 71.6 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L28 family RabGAP-TBC PF00566.13 CAR30133.1 - 1e-48 165.6 0.0 2.6e-48 164.3 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DivIC PF04977.10 CAR30133.1 - 0.0024 17.2 19.2 0.26 10.7 1.2 3.7 2 1 1 3 3 3 3 Septum formation initiator Phlebovirus_NSM PF07246.6 CAR30133.1 - 0.14 11.3 11.4 0.047 12.8 3.0 2.3 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M ADIP PF11559.3 CAR30133.1 - 0.3 10.9 16.6 1.3 8.8 6.3 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.6 CAR30133.1 - 1.5 8.6 7.4 0.29 10.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.1 CAR30133.1 - 1.9 8.5 18.9 1.1 9.2 7.2 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.10 CAR30133.1 - 7.5 6.4 23.9 0.19 11.5 4.1 3.6 3 0 0 3 3 3 0 Basic region leucine zipper PLAC9 PF15205.1 CAR30134.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Placenta-specific protein 9 Fungal_trans PF04082.13 CAR30135.1 - 3.5e-22 78.5 0.4 8.7e-22 77.2 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 CAR30135.1 - 1.2e-11 44.3 0.0 2.8e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.13 CAR30135.1 - 2e-09 37.1 13.7 3.5e-09 36.4 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HutD PF05962.6 CAR30135.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 HutD RQC PF09382.5 CAR30136.1 - 3.8e-27 94.0 0.2 8.4e-27 92.9 0.1 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 CAR30136.1 - 4.1e-22 78.4 0.0 1.3e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30136.1 - 3.2e-20 71.7 0.0 1.9e-18 66.1 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_Sgs1 PF11408.3 CAR30136.1 - 2.4e-09 36.9 0.0 5.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Sgs1 RecQ helicase HRDC PF00570.18 CAR30136.1 - 0.0014 18.3 0.0 0.0057 16.3 0.0 2.0 1 0 0 1 1 1 1 HRDC domain MFS_1 PF07690.11 CAR30137.1 - 2.4e-27 95.5 9.2 6.4e-27 94.1 5.0 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily GDC-P PF02347.11 CAR30138.1 - 2.4e-199 662.4 0.0 1.2e-183 610.6 0.0 2.1 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CAR30138.1 - 0.0017 17.1 0.0 0.036 12.8 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR30138.1 - 0.0022 17.2 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase WD40 PF00400.27 CAR30139.1 - 1.5e-23 81.7 10.4 3.5e-07 29.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Glyco_hydro_43 PF04616.9 CAR30139.1 - 0.061 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 Serglycin PF04360.7 CAR30139.1 - 0.29 10.8 2.7 1.3 8.7 1.8 2.1 2 1 0 2 2 2 0 Serglycin Ribosomal_S17 PF00366.15 CAR30140.1 - 1.3e-14 53.9 0.5 2.9e-14 52.8 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 Rhomboid PF01694.17 CAR30141.1 - 3.8e-15 56.1 11.5 3.8e-15 56.1 8.0 2.0 2 0 0 2 2 2 1 Rhomboid family DUF2075 PF09848.4 CAR30142.1 - 3.8e-101 338.5 0.0 4.9e-101 338.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CAR30142.1 - 3.7e-09 36.8 0.0 9.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CAR30142.1 - 5.5e-05 23.0 0.0 0.085 12.6 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CAR30142.1 - 0.00015 21.8 0.0 0.00038 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 CAR30142.1 - 0.00082 19.0 0.1 0.0049 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CAR30142.1 - 0.0009 19.4 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CAR30142.1 - 0.004 16.8 0.0 0.0083 15.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 CAR30142.1 - 0.0053 17.0 0.2 0.17 12.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CAR30142.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CAR30142.1 - 0.023 14.4 0.1 0.12 12.0 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 CAR30142.1 - 0.027 14.2 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 CAR30142.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Zds_C PF08632.5 CAR30142.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term AAA_33 PF13671.1 CAR30142.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 CAR30142.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF258 PF03193.11 CAR30142.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CAR30142.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 CAR30142.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UAA PF08449.6 CAR30143.1 - 7.3e-74 248.4 11.9 8.3e-74 248.2 8.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CAR30143.1 - 1.1e-09 38.3 15.5 3e-09 36.9 2.0 3.3 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 CAR30143.1 - 6.2e-08 32.4 2.2 6.2e-08 32.4 1.5 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CAR30143.1 - 0.0048 17.0 19.3 0.049 13.8 0.0 3.4 2 2 1 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CAR30143.1 - 0.061 12.4 7.0 0.29 10.1 0.4 2.2 1 1 0 2 2 2 0 Nucleotide-sugar transporter RINGv PF12906.2 CAR30145.1 - 3.5e-06 26.9 5.9 8.2e-06 25.7 4.1 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 CAR30145.1 - 0.071 13.0 7.6 0.33 10.9 2.8 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.1 CAR30145.1 - 0.52 10.1 9.3 0.05 13.4 2.5 2.1 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 CAR30145.1 - 0.94 9.6 6.8 0.64 10.1 3.1 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger RasGAP_C PF03836.10 CAR30146.1 - 1.2e-18 67.1 7.9 1.2e-18 67.1 5.5 2.3 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 CAR30146.1 - 4.6e-16 59.0 0.2 4.6e-16 59.0 0.1 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 CAR30146.1 - 1.8e-11 44.0 0.0 5.1e-10 39.3 0.0 3.3 2 0 0 2 2 2 1 Calponin homology (CH) domain RP-C_C PF11800.3 CAR30146.1 - 0.00084 19.0 2.2 0.004 16.8 1.5 2.2 1 0 0 1 1 1 1 Replication protein C C-terminal region Takusan PF04822.8 CAR30146.1 - 0.019 14.7 4.9 0.71 9.6 0.3 3.0 2 0 0 2 2 2 0 Takusan IQ PF00612.22 CAR30146.1 - 0.052 13.2 11.8 2.9 7.7 0.1 6.9 8 0 0 8 8 8 0 IQ calmodulin-binding motif TBCC PF07986.7 CAR30147.1 - 0.069 12.5 2.6 0.42 10.0 1.1 2.3 1 1 0 1 1 1 0 Tubulin binding cofactor C HSP90 PF00183.13 CAR30148.1 - 8.8e-254 842.8 34.3 1e-253 842.5 23.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CAR30148.1 - 4.4e-11 42.4 0.0 9.6e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CAR30148.1 - 8e-11 41.7 0.0 8e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 CAR30148.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Tom37_C PF11801.3 CAR30148.1 - 4.3 7.1 9.0 23 4.7 2.5 2.7 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF1510 PF07423.6 CAR30148.1 - 5.2 6.3 20.6 0.48 9.7 9.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2435 PF10363.4 CAR30149.1 - 3.2e-31 107.0 0.4 5e-30 103.2 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 CAR30149.1 - 2.3e-05 23.7 0.5 7.1e-05 22.2 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) CENP-B_dimeris PF09026.5 CAR30149.1 - 0.052 13.7 4.2 0.17 12.1 2.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ank_2 PF12796.2 CAR30150.1 - 1.2e-17 64.0 0.1 2.2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CAR30150.1 - 2.3e-17 61.8 0.1 1.4e-09 37.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CAR30150.1 - 3.2e-16 58.9 0.2 7.8e-09 35.4 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CAR30150.1 - 1.7e-13 50.6 0.1 1.8e-10 41.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CAR30150.1 - 2.4e-12 45.8 0.0 4.2e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat DUF4371 PF14291.1 CAR30150.1 - 0.07 12.6 0.2 0.12 11.9 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4371) eIF-5_eIF-2B PF01873.12 CAR30151.1 - 3e-43 146.4 0.2 5.1e-43 145.7 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 CAR30151.1 - 0.0044 16.6 0.1 0.063 12.9 0.0 2.5 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.7 CAR30151.1 - 0.046 13.0 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Methyltransf_13 PF08421.6 CAR30151.1 - 0.11 12.0 0.3 13 5.4 0.1 2.4 1 1 0 2 2 2 0 Putative zinc binding domain XPC-binding PF09280.6 CAR30151.1 - 0.13 11.7 0.1 11 5.5 0.0 2.3 2 0 0 2 2 2 0 XPC-binding domain GOLGA2L5 PF15070.1 CAR30152.1 - 0.069 11.6 0.0 0.091 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Pkinase PF00069.20 CAR30153.1 - 2.9e-39 134.7 0.0 5.7e-39 133.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30153.1 - 3.2e-21 75.5 0.0 2.5e-15 56.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CAR30153.1 - 0.036 13.0 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like TIP49 PF06068.8 CAR30154.1 - 5.7e-179 594.9 4.3 6.8e-179 594.7 3.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CAR30154.1 - 2.6e-08 34.1 0.5 3.9e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CAR30154.1 - 5.4e-08 32.1 2.7 7.7e-05 21.8 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CAR30154.1 - 1.5e-05 25.1 0.1 0.044 13.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain DnaB_C PF03796.10 CAR30154.1 - 2.2e-05 23.4 0.1 4.6e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 CAR30154.1 - 3.6e-05 23.8 0.1 0.00033 20.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CAR30154.1 - 0.00037 20.4 0.4 2 8.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CAR30154.1 - 0.0024 17.0 1.0 0.045 12.9 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CAR30154.1 - 0.0032 16.8 0.2 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CAR30154.1 - 0.0036 17.0 0.2 0.65 9.7 0.0 2.8 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CAR30154.1 - 0.0098 15.8 0.1 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CAR30154.1 - 0.035 13.5 0.0 7.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 CAR30154.1 - 0.044 13.5 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 CAR30154.1 - 0.074 12.6 0.1 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CAR30154.1 - 0.075 12.1 0.3 0.16 11.0 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin ATP-synt_C PF00137.16 CAR30155.1 - 2.3e-27 94.6 30.1 4.9e-15 55.1 3.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 CAR30155.1 - 0.0094 15.4 1.4 0.0094 15.4 1.0 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Mis14 PF08641.7 CAR30156.1 - 5.4e-24 84.8 5.7 5.4e-24 84.8 3.9 1.8 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Gemini_AL1_M PF08283.6 CAR30156.1 - 0.015 15.0 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 Geminivirus rep protein central domain ITI_HC_C PF06668.7 CAR30156.1 - 0.12 11.7 0.8 0.41 10.0 0.2 1.8 1 1 0 2 2 2 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Complex1_LYR_2 PF13233.1 CAR30156.1 - 0.27 11.7 5.1 31 5.1 3.5 2.3 1 1 0 1 1 1 0 Complex1_LYR-like ING PF12998.2 CAR30156.1 - 1.5 9.1 7.2 17 5.7 0.0 3.6 2 2 2 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding Mit_ribos_Mrp51 PF11709.3 CAR30156.1 - 1.6 7.8 7.3 0.94 8.6 0.7 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein subunit DUF4407 PF14362.1 CAR30156.1 - 7.6 5.3 11.8 0.19 10.6 3.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SNARE PF05739.14 CAR30157.1 - 9.1e-15 54.1 7.9 9.1e-15 54.1 5.5 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CAR30157.1 - 2.1e-06 27.8 18.9 8.1e-06 25.9 4.3 2.4 2 1 0 2 2 2 2 Syntaxin Synaptobrevin PF00957.16 CAR30157.1 - 0.00012 21.6 2.5 0.00012 21.6 1.8 2.4 2 0 0 2 2 2 1 Synaptobrevin Rifin_STEVOR PF02009.11 CAR30157.1 - 0.0017 18.0 7.4 0.0031 17.1 4.9 1.7 1 1 0 1 1 1 1 Rifin/stevor family Thr_dehydrat_C PF00585.13 CAR30157.1 - 0.0026 17.3 1.6 0.019 14.5 0.0 2.9 3 1 0 3 3 3 1 C-terminal regulatory domain of Threonine dehydratase T2SF PF00482.18 CAR30157.1 - 0.0062 16.4 0.4 0.0062 16.4 0.3 2.0 3 0 0 3 3 1 1 Type II secretion system (T2SS), protein F Baculo_PEP_C PF04513.7 CAR30157.1 - 0.061 13.1 9.1 0.22 11.3 0.8 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3225 PF11533.3 CAR30157.1 - 0.12 12.0 1.5 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) DUF3753 PF12575.3 CAR30157.1 - 0.14 11.9 0.8 0.71 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) PTA_PTB PF01515.14 CAR30157.1 - 0.26 10.3 6.4 0.27 10.2 3.7 1.6 1 1 0 1 1 1 0 Phosphate acetyl/butaryl transferase Herpes_US9 PF06072.6 CAR30157.1 - 0.32 10.8 1.4 0.7 9.7 1.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF2116 PF09889.4 CAR30157.1 - 0.32 10.8 1.3 1 9.1 0.9 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4094 PF13334.1 CAR30157.1 - 0.35 11.2 0.2 0.35 11.2 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4094) DUF2277 PF10041.4 CAR30157.1 - 0.56 10.2 3.1 5.7 6.9 0.5 3.0 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) Allexi_40kDa PF05549.6 CAR30157.1 - 0.7 9.1 8.5 1.2 8.4 0.7 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF3708 PF12501.3 CAR30157.1 - 2 8.2 10.7 0.28 11.0 2.0 2.4 1 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF4449 PF14613.1 CAR30157.1 - 2 8.3 9.0 0.54 10.1 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4449) PBP1_TM PF14812.1 CAR30157.1 - 3 8.2 6.8 0.74 10.1 0.1 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1664 PF07889.7 CAR30157.1 - 3.2 7.5 8.4 0.58 9.9 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF912 PF06024.7 CAR30157.1 - 8.4 6.5 10.1 0.18 11.8 0.6 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ketoacyl-synt PF00109.21 CAR30158.1 - 1.9e-19 70.1 0.0 1.9e-19 70.1 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 CAR30158.1 - 1.3e-14 53.9 0.0 3.1e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 CAR30158.1 - 3e-10 39.9 0.0 7.9e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 CAR30158.1 - 4.5e-05 23.4 0.0 0.00018 21.4 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR30158.1 - 0.001 18.7 0.1 0.0058 16.3 0.0 2.2 2 0 0 2 2 2 1 KR domain DUF4452 PF14618.1 CAR30159.1 - 0.0006 19.6 2.8 0.031 14.0 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4452) mRNA_triPase PF02940.10 CAR30160.1 - 1.3e-58 198.2 2.5 1.7e-58 197.8 0.9 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.21 CAR30161.1 - 1.3e-23 83.5 0.0 1.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CAR30161.1 - 3.8e-05 23.5 0.0 6.4e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CAR30161.1 - 0.072 12.1 0.0 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ABC_tran PF00005.22 CAR30163.1 - 7.6e-48 162.2 0.0 7.8e-26 91.0 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAR30163.1 - 3.6e-16 59.9 3.2 2.2e-06 27.8 0.0 4.0 3 1 0 4 4 3 3 AAA domain SMC_N PF02463.14 CAR30163.1 - 2.2e-12 46.7 0.0 0.0016 17.6 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 CAR30163.1 - 1.5e-08 34.1 0.9 3.4e-08 33.0 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.1 CAR30163.1 - 2.7e-08 34.4 0.1 0.00049 20.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAR30163.1 - 1.2e-07 31.1 0.4 0.01 15.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CAR30163.1 - 1.4e-06 27.6 0.1 0.0064 15.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAR30163.1 - 2.2e-06 28.4 0.0 0.087 13.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CAR30163.1 - 2.5e-06 26.8 0.5 0.23 10.4 0.0 3.8 2 1 1 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.18 CAR30163.1 - 6.3e-06 26.1 0.0 0.027 14.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 CAR30163.1 - 1.2e-05 24.9 1.1 0.21 10.9 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 CAR30163.1 - 1.4e-05 25.2 0.1 0.26 11.4 0.0 3.5 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CAR30163.1 - 6e-05 23.5 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 CAR30163.1 - 6e-05 23.1 0.2 1.7 8.8 0.0 3.6 3 0 0 3 3 3 2 RNA helicase DUF87 PF01935.12 CAR30163.1 - 6.6e-05 22.8 1.8 0.035 13.9 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function DUF87 MobB PF03205.9 CAR30163.1 - 0.0002 21.1 0.1 0.33 10.6 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CAR30163.1 - 0.00026 20.6 0.1 0.38 10.3 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 CAR30163.1 - 0.00028 19.7 0.3 0.52 9.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_18 PF13238.1 CAR30163.1 - 0.00038 20.7 2.0 0.019 15.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CAR30163.1 - 0.00059 19.7 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CAR30163.1 - 0.001 18.7 0.5 2.4 7.7 0.1 3.3 3 1 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 CAR30163.1 - 0.0012 18.7 0.1 1.9 8.4 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CAR30163.1 - 0.0019 18.3 0.0 6.5 6.9 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CAR30163.1 - 0.0023 17.8 0.0 0.24 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 CAR30163.1 - 0.0034 15.9 0.0 1.1 7.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CAR30163.1 - 0.004 17.0 0.1 1.8 8.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CAR30163.1 - 0.0098 15.8 0.9 0.97 9.3 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain Thymidylate_kin PF02223.12 CAR30163.1 - 0.015 14.6 0.1 0.17 11.2 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Dynamin_N PF00350.18 CAR30163.1 - 0.015 15.0 0.5 1.3 8.8 0.0 3.5 4 0 0 4 4 3 0 Dynamin family Zeta_toxin PF06414.7 CAR30163.1 - 0.025 13.6 0.1 2.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.8 CAR30163.1 - 0.027 13.3 0.1 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CAR30163.1 - 0.04 13.6 0.0 8.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 CAR30163.1 - 0.044 13.5 0.1 5.5 6.6 0.0 2.9 3 0 0 3 3 2 0 NTPase AAA_25 PF13481.1 CAR30163.1 - 0.05 12.9 0.0 12 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CAR30163.1 - 0.051 13.0 0.1 17 4.7 0.0 3.2 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.3 CAR30163.1 - 0.061 10.6 1.3 2.9 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MutS_V PF00488.16 CAR30163.1 - 0.074 12.4 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 MutS domain V DUF1673 PF07895.6 CAR30163.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) ABC_ATPase PF09818.4 CAR30163.1 - 0.12 10.8 1.1 0.83 8.1 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class PduV-EutP PF10662.4 CAR30163.1 - 0.15 11.5 0.1 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MoCF_biosynth PF00994.19 CAR30164.1 - 3.9e-31 107.3 0.0 7.2e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Polysacc_synt_4 PF04669.8 CAR30165.1 - 5e-21 74.9 2.2 4.8e-20 71.7 1.6 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis YcbB PF08664.5 CAR30165.1 - 0.081 12.7 1.0 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 YcbB domain Cation_efflux PF01545.16 CAR30166.1 - 6.9e-44 150.0 1.1 9.5e-44 149.5 0.8 1.1 1 0 0 1 1 1 1 Cation efflux family ARID PF01388.16 CAR30167.1 - 1.2e-23 82.7 0.0 3.7e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 CAR30167.1 - 5e-17 62.1 0.0 1.4e-09 38.1 0.0 2.9 2 0 0 2 2 2 2 JmjC domain, hydroxylase PLU-1 PF08429.6 CAR30167.1 - 1.2e-11 44.1 0.5 8.4e-11 41.3 0.4 2.5 1 1 0 1 1 1 1 PLU-1-like protein PHD PF00628.24 CAR30167.1 - 3.9e-07 29.6 9.7 8.5e-07 28.5 6.7 1.6 1 0 0 1 1 1 1 PHD-finger HisKA PF00512.20 CAR30167.1 - 0.0074 16.2 0.1 0.027 14.4 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain zf-RING_2 PF13639.1 CAR30167.1 - 0.056 13.2 7.5 0.13 12.0 5.2 1.7 1 0 0 1 1 1 0 Ring finger domain JmjN PF02375.12 CAR30167.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 jmjN domain GCR1_C PF12550.3 CAR30171.1 - 1.6e-22 79.1 0.2 3.4e-22 78.1 0.2 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes UPF0061 PF02696.9 CAR30172.1 - 7.9e-151 502.6 0.0 9.8e-151 502.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Lon_C PF05362.8 CAR30173.1 - 8.1e-46 155.9 0.0 1.5e-45 155.0 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CAR30173.1 - 1.3e-19 70.7 0.0 2.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CAR30173.1 - 1.7e-09 37.7 0.2 6.6e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 CAR30173.1 - 1.5e-07 31.1 0.0 5.2e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 CAR30173.1 - 1.4e-06 27.7 0.0 2.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 CAR30173.1 - 4e-05 23.6 0.0 0.00013 22.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CAR30173.1 - 0.00011 22.1 0.0 0.00034 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CAR30173.1 - 0.00073 20.3 0.0 0.0028 18.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CAR30173.1 - 0.0015 17.6 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.1 CAR30173.1 - 0.0018 18.6 0.5 0.0071 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CAR30173.1 - 0.0024 18.0 0.0 0.054 13.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CAR30173.1 - 0.0032 16.5 0.0 0.0085 15.1 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 CAR30173.1 - 0.004 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CAR30173.1 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CAR30173.1 - 0.0081 16.0 0.0 0.028 14.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CAR30173.1 - 0.011 14.9 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 CAR30173.1 - 0.011 14.4 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain IstB_IS21 PF01695.12 CAR30173.1 - 0.021 14.2 0.1 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 CAR30173.1 - 0.032 13.9 0.0 6.2 6.4 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 CAR30173.1 - 0.037 13.6 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CAR30173.1 - 0.044 13.5 0.1 0.22 11.2 0.0 2.0 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.1 CAR30173.1 - 0.049 13.9 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.4 CAR30173.1 - 0.057 13.3 0.2 0.16 11.8 0.0 1.8 2 0 0 2 2 1 0 C-terminal, D2-small domain, of ClpB protein ABC_tran PF00005.22 CAR30173.1 - 0.061 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter SMC_N PF02463.14 CAR30173.1 - 0.1 11.7 0.2 6.8 5.8 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CAR30173.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CAR30173.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CAR30173.1 - 0.2 11.0 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lsr2 PF11774.3 CAR30173.1 - 0.23 11.3 0.0 0.54 10.1 0.0 1.6 1 0 0 1 1 1 0 Lsr2 TRP PF06011.7 CAR30174.1 - 7.7e-146 486.1 31.9 1.2e-145 485.4 22.1 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CAR30174.1 - 7.4e-43 145.9 0.2 1.3e-42 145.2 0.2 1.4 1 0 0 1 1 1 1 ML-like domain DUF4459 PF14673.1 CAR30174.1 - 0.02 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Coatomer_WDAD PF04053.9 CAR30176.1 - 1.4e-159 531.6 0.0 2.3e-159 530.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CAR30176.1 - 2.1e-46 154.2 4.0 3.1e-10 39.5 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CAR30176.1 - 5.9e-05 21.4 3.7 0.054 11.6 0.0 4.0 4 1 0 5 5 5 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 CAR30176.1 - 0.0001 22.0 0.1 0.12 12.1 0.0 3.8 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region TPR_11 PF13414.1 CAR30176.1 - 0.049 13.2 2.9 0.14 11.7 0.7 2.6 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 CAR30176.1 - 0.71 9.9 4.0 15 5.7 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat FtsJ PF01728.14 CAR30177.1 - 7.1e-61 205.3 0.0 8.9e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CAR30177.1 - 9e-06 25.5 0.0 6.5e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR30177.1 - 0.00027 20.5 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CAR30177.1 - 0.012 16.1 0.0 0.037 14.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L1 PF00687.16 CAR30178.1 - 3.1e-46 157.4 2.6 3.8e-46 157.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cyclin PF08613.6 CAR30179.1 - 1.5e-18 67.6 0.1 2.3e-18 67.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAR30179.1 - 0.00023 20.7 0.3 0.00044 19.8 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain GTSE1_N PF15259.1 CAR30179.1 - 0.053 13.4 0.7 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Arf PF00025.16 CAR30180.1 - 9.2e-67 223.6 0.0 1e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CAR30180.1 - 2.8e-09 36.1 0.5 4.3e-06 25.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CAR30180.1 - 7.7e-09 36.0 0.0 1.1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CAR30180.1 - 4.1e-08 32.6 0.0 5.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CAR30180.1 - 1.2e-07 31.2 0.0 1.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CAR30180.1 - 4.1e-06 26.7 0.0 5.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAR30180.1 - 8.3e-05 21.8 0.0 9.1e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CAR30180.1 - 0.0012 18.2 0.1 0.023 14.1 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CAR30180.1 - 0.03 13.8 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tegument_dsDNA PF12818.2 CAR30180.1 - 0.054 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein DUF663 PF04950.7 CAR30181.1 - 1.4e-101 339.3 0.1 1.4e-101 339.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CAR30181.1 - 3.7e-28 96.8 0.0 1.1e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CAR30181.1 - 2.2e-09 37.0 0.0 2.7e-07 30.2 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.24 CAR30181.1 - 4.1e-06 27.0 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CAR30181.1 - 7.2e-05 22.9 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CAR30181.1 - 0.00011 22.1 0.0 0.00037 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CAR30181.1 - 0.00012 22.9 0.0 0.00012 22.9 0.0 3.3 3 1 1 4 4 2 1 AAA domain AAA_19 PF13245.1 CAR30181.1 - 0.00013 21.6 0.2 0.00032 20.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CAR30181.1 - 0.00014 21.9 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 CAR30181.1 - 0.00014 21.5 0.0 0.00052 19.7 0.0 2.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CAR30181.1 - 0.00025 21.5 0.0 0.0011 19.4 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR30181.1 - 0.0013 18.6 0.1 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 CAR30181.1 - 0.0023 17.6 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 CAR30181.1 - 0.0042 16.6 0.2 0.013 15.1 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CAR30181.1 - 0.0049 16.8 0.1 0.017 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CAR30181.1 - 0.0055 16.1 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CAR30181.1 - 0.0063 16.8 0.0 0.0063 16.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 CAR30181.1 - 0.0085 16.2 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 CAR30181.1 - 0.011 15.5 0.9 0.022 14.5 0.6 1.5 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.9 CAR30181.1 - 0.011 15.3 0.1 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.14 CAR30181.1 - 0.018 14.4 0.2 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CAR30181.1 - 0.028 14.7 1.8 0.044 14.0 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_11 PF13086.1 CAR30181.1 - 0.04 13.4 0.0 0.04 13.4 0.0 3.2 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 CAR30181.1 - 0.062 12.7 0.1 1.1 8.6 0.0 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CAR30181.1 - 0.13 11.7 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRP_SPB PF02978.14 CAR30181.1 - 0.16 12.2 6.0 12 6.2 2.3 3.0 2 0 0 2 2 2 0 Signal peptide binding domain WAC_Acf1_DNA_bd PF10537.4 CAR30182.1 - 3.4e-36 123.4 1.9 1.5e-35 121.4 1.3 2.2 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CAR30182.1 - 1.5e-09 37.4 0.3 4.2e-09 36.0 0.2 1.7 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 CAR30182.1 - 0.0001 22.0 0.6 0.00024 20.9 0.4 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 EMG1 PF03587.9 CAR30182.1 - 0.0076 15.5 0.1 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ubiq_cyt_C_chap PF03981.7 CAR30183.1 - 2.9e-42 143.8 0.4 4.5e-42 143.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.10 CAR30184.1 - 1.4e-83 279.8 1.4 2e-83 279.3 1.0 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CAR30184.1 - 6e-59 198.1 0.0 8.6e-59 197.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI LRR_9 PF14580.1 CAR30185.1 - 1.8e-13 50.4 0.0 2.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CAR30185.1 - 3e-10 39.4 4.7 5.9e-05 22.5 0.0 3.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CAR30185.1 - 8.8e-07 28.1 7.3 1.8 8.9 0.1 4.9 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CAR30185.1 - 6.1e-05 22.5 7.7 1.3 9.5 0.1 5.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_8 PF13855.1 CAR30185.1 - 8.4e-05 22.2 5.2 0.15 11.8 0.1 3.1 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CAR30185.1 - 0.0033 17.3 3.4 52 4.3 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich repeat FliG_C PF01706.11 CAR30185.1 - 0.056 13.4 0.2 0.92 9.5 0.1 2.5 2 1 0 3 3 3 0 FliG C-terminal domain BAH PF01426.13 CAR30186.1 - 4.7e-15 55.3 0.3 1.3e-14 53.9 0.2 1.8 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 CAR30186.1 - 3e-08 33.2 31.3 1.9e-06 27.4 7.4 6.5 7 0 0 7 7 7 3 PHD-finger Myb_DNA-binding PF00249.26 CAR30186.1 - 0.0026 17.7 0.2 0.009 16.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain PHD_2 PF13831.1 CAR30186.1 - 0.0028 16.9 1.8 0.0028 16.9 1.3 5.6 4 1 0 4 4 4 2 PHD-finger DUF445 PF04286.7 CAR30186.1 - 0.83 9.1 8.3 2.2 7.7 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) mRNA_cap_enzyme PF01331.14 CAR30187.1 - 2e-58 197.2 0.0 3.8e-58 196.3 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CAR30187.1 - 8.9e-20 70.9 0.3 9.8e-19 67.6 0.2 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CAR30187.1 - 7.8e-07 28.6 0.0 4.8e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DAP3 PF10236.4 CAR30188.1 - 1.1e-81 274.1 0.3 1.7e-81 273.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CAR30188.1 - 6.4e-08 32.8 0.0 1.8e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CAR30188.1 - 0.0002 21.5 0.1 0.0031 17.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAR30188.1 - 0.0013 18.2 0.1 0.18 11.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 CAR30188.1 - 0.0015 17.7 0.0 0.0067 15.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CAR30188.1 - 0.0015 18.8 0.1 0.85 9.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_14 PF13173.1 CAR30188.1 - 0.013 15.4 0.6 0.57 10.0 0.0 3.1 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 CAR30188.1 - 0.016 14.9 0.1 0.21 11.2 0.0 2.8 3 2 0 3 3 3 0 NACHT domain Sigma54_activat PF00158.21 CAR30188.1 - 0.018 14.5 0.0 0.089 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 CAR30188.1 - 0.036 13.7 0.1 0.3 10.7 0.0 2.5 2 1 0 3 3 3 0 NTPase AAA PF00004.24 CAR30188.1 - 0.042 14.0 0.0 0.63 10.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CAR30188.1 - 0.049 12.5 0.0 0.097 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2183 PF09949.4 CAR30188.1 - 0.051 13.5 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) PseudoU_synth_1 PF01416.15 CAR30189.1 - 1.1e-22 80.4 0.0 1e-11 45.2 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase UPF0113 PF03657.8 CAR30190.1 - 4.2e-12 46.0 0.0 5.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 CAR30190.1 - 0.031 14.3 0.0 0.061 13.4 0.0 1.6 2 0 0 2 2 2 0 pre-rRNA processing and ribosome biogenesis DUF4216 PF13952.1 CAR30190.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4216) SRP72 PF08492.7 CAR30191.1 - 5.4e-11 42.7 3.9 5.4e-11 42.7 2.7 2.5 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_12 PF13424.1 CAR30191.1 - 5.5e-07 29.4 10.1 7.4e-05 22.6 0.9 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CAR30191.1 - 5.1e-06 26.6 0.6 8.7 7.2 0.0 5.7 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 CAR30191.1 - 1.9e-05 24.2 6.5 0.34 10.9 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CAR30191.1 - 0.00076 19.7 5.0 0.7 10.2 1.5 4.1 3 1 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR30191.1 - 0.00084 19.4 9.8 0.066 13.3 0.3 4.3 3 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CAR30191.1 - 0.0022 18.6 0.3 20 5.9 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CAR30191.1 - 0.0084 15.7 12.2 0.15 11.6 0.5 4.2 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.1 CAR30191.1 - 0.015 15.0 0.1 0.37 10.7 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR30191.1 - 0.019 15.4 1.6 35 5.1 0.1 4.9 5 1 1 6 6 4 0 Tetratricopeptide repeat PPR PF01535.15 CAR30191.1 - 0.021 14.7 1.2 2.6 8.1 0.0 4.4 5 0 0 5 5 5 0 PPR repeat TPR_1 PF00515.23 CAR30191.1 - 0.029 13.9 1.9 1.5 8.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CAR30191.1 - 0.041 13.6 9.4 0.31 10.9 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 CAR30191.1 - 0.14 11.5 3.3 4.2 6.7 0.1 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DEAD PF00270.24 CAR30192.1 - 6.8e-29 100.5 0.1 1.7e-27 95.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30192.1 - 1.2e-14 53.9 0.0 3.6e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR30192.1 - 9.4e-07 28.8 0.1 3.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CAR30192.1 - 0.0023 16.7 0.1 0.004 15.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CAR30192.1 - 0.049 13.7 0.0 0.43 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 CAR30193.1 - 1.3e-74 250.6 0.3 1.6e-74 250.3 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30193.1 - 5.2e-48 163.3 0.0 6.6e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30193.1 - 7.8e-08 31.6 0.0 4.4e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CAR30193.1 - 0.00083 18.4 0.2 0.0033 16.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CAR30193.1 - 0.025 13.8 0.1 0.071 12.4 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SET PF00856.23 CAR30194.1 - 6.6e-08 33.0 0.0 1.9e-07 31.5 0.0 1.8 2 1 0 2 2 2 1 SET domain ATP-synt_B PF00430.13 CAR30194.1 - 0.87 9.3 3.7 9.9 5.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Radical_SAM PF04055.16 CAR30195.1 - 1.8e-23 83.5 0.0 8.9e-23 81.2 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 CAR30195.1 - 8.5e-23 80.2 0.0 2.3e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 CAR30195.1 - 1.3e-10 41.4 0.0 3.8e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin DUF1992 PF09350.5 CAR30196.1 - 1.2e-18 66.6 0.1 5.2e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Glycos_transf_1 PF00534.15 CAR30197.1 - 1e-33 116.2 0.0 5.8e-32 110.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CAR30197.1 - 5.5e-08 32.7 0.1 1.6e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CAR30197.1 - 6.2e-08 32.8 0.0 2.9e-06 27.4 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CAR30197.1 - 2.1e-05 24.7 0.0 3.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Methyltransf_8 PF05148.10 CAR30197.1 - 0.055 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase SCA7 PF08313.7 CAR30198.1 - 3.4e-32 109.8 0.9 3.4e-32 109.8 0.6 2.8 2 1 0 2 2 2 1 SCA7, zinc-binding domain DUF342 PF03961.8 CAR30198.1 - 0.095 11.0 10.9 0.15 10.4 6.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Herpes_env PF01673.13 CAR30198.1 - 1.1 7.6 13.9 2.1 6.8 9.6 1.4 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Cellulose_synt PF03552.9 CAR30198.1 - 3.9 5.6 6.2 5.7 5.1 4.3 1.2 1 0 0 1 1 1 0 Cellulose synthase GDPD PF03009.12 CAR30199.1 - 3.7e-33 115.0 0.2 2.1e-32 112.6 0.2 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family NUDIX PF00293.23 CAR30200.1 - 3.2e-16 59.1 0.0 5.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 CAR30200.1 - 5.5e-08 32.1 0.3 9.4e-08 31.4 0.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 CAR30200.1 - 0.00067 19.9 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Pkinase PF00069.20 CAR30201.1 - 2.8e-40 138.1 0.0 4.8e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30201.1 - 1.3e-13 50.6 0.0 2.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CAR30201.1 - 0.0078 15.9 1.0 0.071 12.8 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CAR30201.1 - 0.037 12.8 0.1 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase OTCace PF00185.19 CAR30201.1 - 0.092 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pkinase PF00069.20 CAR30202.1 - 2.2e-70 236.7 0.0 2.6e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30202.1 - 3.3e-39 134.5 0.0 4.2e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30202.1 - 6.1e-06 25.4 0.0 1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CAR30202.1 - 0.014 14.7 0.1 0.033 13.5 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CAR30202.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CAR30202.1 - 0.16 10.7 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L12 PF00542.14 CAR30203.1 - 1.8e-20 72.6 11.1 4.7e-20 71.3 5.6 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 CAR30203.1 - 0.00027 21.2 9.3 0.00027 21.2 6.4 2.5 1 1 0 2 2 2 1 60s Acidic ribosomal protein YejG PF13989.1 CAR30203.1 - 0.12 12.4 0.1 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 YejG-like protein RNA_POL_M_15KD PF02150.11 CAR30204.1 - 6.8e-15 54.4 3.4 6.8e-15 54.4 2.4 2.4 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CAR30204.1 - 2e-14 52.9 1.5 2e-14 52.9 1.1 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 CAR30204.1 - 0.00049 20.3 2.8 0.0097 16.1 0.2 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Rubredoxin PF00301.15 CAR30204.1 - 0.066 13.0 3.4 47 3.9 0.0 4.0 4 0 0 4 4 4 0 Rubredoxin DUF2387 PF09526.5 CAR30204.1 - 0.066 13.1 2.7 5.2 7.0 0.2 2.3 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 CAR30204.1 - 0.12 12.2 8.7 0.4 10.5 0.6 2.5 2 1 0 2 2 2 0 Double zinc ribbon GFA PF04828.9 CAR30204.1 - 0.15 12.0 4.1 4.6 7.2 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_4 PF07975.7 CAR30204.1 - 0.22 11.5 10.5 0.57 10.2 0.7 3.0 2 1 2 4 4 4 0 TFIIH C1-like domain IBR PF01485.16 CAR30204.1 - 0.36 10.7 6.9 1.6 8.6 0.4 2.7 2 1 0 2 2 2 0 IBR domain Zn_Tnp_IS1595 PF12760.2 CAR30204.1 - 0.4 10.5 11.9 2.7 7.8 2.8 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DUF2296 PF10058.4 CAR30204.1 - 0.52 10.0 6.3 0.63 9.8 0.3 2.5 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 CAR30204.1 - 1.5 8.8 12.4 5.6 7.0 0.0 3.9 3 1 1 4 4 4 0 Zinc ribbon domain zf-CHY PF05495.7 CAR30204.1 - 1.9 8.6 9.0 1.1 9.4 0.8 2.4 2 1 0 2 2 2 0 CHY zinc finger zf-UBP PF02148.14 CAR30204.1 - 2.3 8.4 6.1 1.7 8.8 0.3 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Cytochrom_NNT PF03264.9 CAR30204.1 - 2.8 7.3 7.4 0.1 12.0 0.4 2.0 2 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Rpr2 PF04032.11 CAR30204.1 - 3.1 7.7 6.0 18 5.2 1.1 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HypA PF01155.14 CAR30204.1 - 4 7.1 8.0 22 4.7 3.4 2.8 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF3795 PF12675.2 CAR30204.1 - 5.3 7.2 6.6 2.8 8.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) AFT PF08731.6 CAR30205.1 - 7e-47 158.2 0.9 7e-47 158.2 0.6 1.7 2 0 0 2 2 2 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 CAR30205.1 - 0.0004 19.8 0.5 0.61 9.6 0.0 2.4 2 0 0 2 2 2 2 MuDR family transposase FAR1 PF03101.10 CAR30205.1 - 0.0031 17.9 0.3 0.0086 16.5 0.2 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain HSF_DNA-bind PF00447.12 CAR30207.1 - 3.7e-35 120.2 2.1 6.5e-35 119.4 1.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Nup54 PF13874.1 CAR30207.1 - 0.1 12.2 3.3 3.6 7.2 1.0 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Tropomyosin_1 PF12718.2 CAR30208.1 - 0.0084 15.9 7.6 0.012 15.4 4.6 1.7 1 1 0 1 1 1 1 Tropomyosin like SlyX PF04102.7 CAR30208.1 - 0.013 15.8 8.4 0.067 13.5 0.2 3.3 2 1 1 3 3 3 0 SlyX TSC22 PF01166.13 CAR30208.1 - 0.02 14.8 2.0 0.96 9.4 0.3 3.2 2 1 0 2 2 2 0 TSC-22/dip/bun family ATG16 PF08614.6 CAR30208.1 - 0.21 11.4 14.3 2.4 7.9 5.9 3.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CCDC155 PF14662.1 CAR30208.1 - 0.38 10.3 7.4 2.1 7.9 5.1 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Mnd1 PF03962.10 CAR30208.1 - 0.96 9.0 7.2 2.7 7.6 0.7 2.2 1 1 1 2 2 2 0 Mnd1 family Lebercilin PF15619.1 CAR30208.1 - 1 8.7 11.0 0.31 10.4 0.7 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Troponin PF00992.15 CAR30208.1 - 2.2 8.3 9.5 7 6.7 0.6 2.5 1 1 1 2 2 2 0 Troponin KLRAQ PF10205.4 CAR30208.1 - 3.3 7.7 7.4 1.1 9.2 0.9 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein AKNA PF12443.3 CAR30208.1 - 3.5 7.6 6.6 11 6.0 0.1 3.1 1 1 2 3 3 3 0 AT-hook-containing transcription factor TMF_DNA_bd PF12329.3 CAR30208.1 - 5.8 6.8 10.7 10 5.9 0.5 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1771 PF08590.5 CAR30209.1 - 4.1e-20 71.5 8.8 4.1e-20 71.5 6.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 CAR30209.1 - 1e-14 54.4 0.0 1e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 Smr domain Dispanin PF04505.7 CAR30209.1 - 0.055 13.0 2.1 0.22 11.0 0.2 2.5 2 0 0 2 2 2 0 Interferon-induced transmembrane protein AAA_11 PF13086.1 CAR30209.1 - 0.68 9.4 10.3 0.63 9.5 1.0 2.1 2 0 0 2 2 2 0 AAA domain DUF912 PF06024.7 CAR30209.1 - 9.8 6.3 8.4 0.4 10.7 0.4 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Myb_DNA-bind_4 PF13837.1 CAR30210.1 - 0.00051 20.1 0.0 0.0049 16.9 0.0 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Ribosomal_L30_N PF08079.7 CAR30211.1 - 7.1e-20 70.8 15.8 1.2e-19 70.0 10.9 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CAR30211.1 - 2.1e-18 65.6 1.7 3.8e-18 64.8 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e AA_permease_2 PF13520.1 CAR30212.1 - 2.8e-50 171.0 46.4 3.5e-50 170.7 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CAR30212.1 - 1.3e-22 79.8 40.4 1.7e-22 79.4 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.24 CAR30213.1 - 3.4e-50 169.8 0.1 2.9e-48 163.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30213.1 - 1.1e-31 108.4 0.0 4.7e-29 100.0 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CAR30213.1 - 2.6e-08 33.9 9.6 6.3e-07 29.3 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CAR30213.1 - 0.0012 17.3 0.1 0.0012 17.3 0.1 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 CAR30213.1 - 0.0012 18.0 16.0 0.0017 17.5 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit TP53IP5 PF15331.1 CAR30213.1 - 4.1 7.2 16.9 7.9 6.3 11.7 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 GAGA_bind PF06217.7 CAR30213.1 - 8.5 6.2 19.1 16 5.3 11.5 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family FA_desaturase PF00487.19 CAR30214.1 - 2.2e-37 128.9 24.0 3.2e-37 128.3 16.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CAR30214.1 - 1e-12 47.6 0.0 2.7e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRCH PF03967.8 CAR30214.1 - 0.21 11.1 0.7 0.42 10.1 0.5 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region TLD PF07534.11 CAR30215.1 - 1.8e-29 102.5 0.0 6.7e-29 100.6 0.0 1.8 1 1 0 1 1 1 1 TLD DUF4599 PF15371.1 CAR30215.1 - 0.073 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) KxDL PF10241.4 CAR30216.1 - 1.1e-10 41.3 0.9 1.4e-10 40.8 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein WXG100 PF06013.7 CAR30216.1 - 0.067 13.2 0.7 0.56 10.2 0.2 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG HSCB_C PF07743.8 CAR30216.1 - 0.36 11.3 3.9 3.8 8.0 0.7 2.6 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Adaptin_N PF01602.15 CAR30217.1 - 9.8e-116 387.1 12.2 1.4e-115 386.6 8.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CAR30217.1 - 2.8e-08 33.8 12.0 2.3e-05 24.2 4.2 3.7 2 2 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CAR30217.1 - 6.5e-08 32.7 0.0 0.028 14.7 0.0 4.9 2 2 3 5 5 5 2 HEAT repeats HEAT PF02985.17 CAR30217.1 - 1.7e-07 30.7 0.2 22 5.4 0.0 7.7 8 0 0 8 8 8 1 HEAT repeat Rad9 PF04139.8 CAR30218.1 - 1.6e-12 47.0 0.1 1.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Rad9 DUF1456 PF07308.8 CAR30218.1 - 0.22 11.6 2.8 2.8 8.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1456) NUFIP1 PF10453.4 CAR30219.1 - 5.6e-16 57.7 6.0 1.6e-15 56.3 4.2 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) FHA PF00498.21 CAR30220.1 - 0.00052 20.0 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain IER PF05760.7 CAR30220.1 - 0.097 12.5 3.6 0.13 12.2 2.5 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) DALR_2 PF09190.6 CAR30220.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 DALR domain DUF544 PF04424.8 CAR30221.1 - 2.9e-27 94.8 0.0 5.4e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) RRM_1 PF00076.17 CAR30222.1 - 3.5e-09 36.1 0.1 8.8e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR30222.1 - 5.2e-07 29.5 0.0 3.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR30222.1 - 0.004 16.9 0.0 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mem_trans PF03547.13 CAR30222.1 - 0.23 9.6 0.0 0.39 8.9 0.0 1.4 1 0 0 1 1 1 0 Membrane transport protein Pkinase PF00069.20 CAR30223.1 - 4.1e-20 72.0 0.0 6.8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30223.1 - 5.3e-12 45.3 0.0 9.2e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MBOAT PF03062.14 CAR30224.1 - 9.4e-60 202.4 23.3 9.4e-60 202.4 16.1 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.12 CAR30225.1 - 1.3e-25 89.6 0.0 2.1e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAD PF05557.8 CAR30226.1 - 5.6e-27 94.1 81.7 1.3e-26 92.9 56.6 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein INCENP_N PF12178.3 CAR30226.1 - 0.0041 16.6 0.0 0.052 13.0 0.0 2.7 3 0 0 3 3 3 1 Chromosome passenger complex (CPC) protein INCENP N terminal UQ_con PF00179.21 CAR30227.1 - 5.1e-17 61.6 0.0 5.7e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAR30227.1 - 0.0044 16.9 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain NAD_kinase PF01513.16 CAR30228.1 - 6.4e-52 176.1 0.0 8.1e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 CAR30228.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Abhydrolase_1 PF00561.15 CAR30229.1 - 5.6e-20 71.8 0.0 7.3e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CAR30229.1 - 1.1e-19 69.5 0.2 1.9e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CAR30229.1 - 8.2e-09 35.6 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CAR30229.1 - 3.4e-06 26.8 0.0 8e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Nif11 PF07862.6 CAR30229.1 - 0.13 12.1 0.0 1.3 9.0 0.0 2.4 3 0 0 3 3 3 0 Nitrogen fixation protein of unknown function MF_alpha PF04648.7 CAR30230.1 - 1.3e-20 72.1 26.5 8.3e-05 22.5 1.1 4.3 4 0 0 4 4 4 4 Yeast mating factor alpha hormone MF_alpha_N PF05436.6 CAR30230.1 - 1.2e-17 63.2 0.5 1.8e-17 62.8 0.3 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus RRM_6 PF14259.1 CAR30232.1 - 2.3e-29 101.1 0.4 3.3e-07 30.1 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CAR30232.1 - 9.9e-27 92.3 2.0 1.8e-08 33.8 0.1 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR30232.1 - 1.2e-21 76.2 1.1 2e-06 27.5 0.2 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR30232.1 - 0.1 12.3 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_60s PF00428.14 CAR30232.1 - 0.5 10.8 4.8 3.7 8.0 0.6 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein XLF PF09302.6 CAR30233.1 - 2.4e-05 24.1 1.1 3.3e-05 23.7 0.8 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) AKNA PF12443.3 CAR30233.1 - 0.0041 17.1 9.6 0.0088 16.0 1.6 2.9 2 1 1 3 3 3 2 AT-hook-containing transcription factor DUF3734 PF12536.3 CAR30233.1 - 0.21 11.7 4.8 0.2 11.7 1.3 2.4 2 0 0 2 2 2 0 Patatin phospholipase MerR-DNA-bind PF09278.6 CAR30233.1 - 0.81 10.1 5.3 17 5.8 0.4 3.5 3 0 0 3 3 3 0 MerR, DNA binding ParA PF10609.4 CAR30234.1 - 2.1e-35 120.4 0.0 6.9e-35 118.7 0.0 1.8 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 CAR30234.1 - 9.5e-17 61.0 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CAR30234.1 - 3.2e-06 26.4 0.0 4.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CAR30234.1 - 0.00017 21.5 0.0 0.00077 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 CAR30234.1 - 0.00028 20.0 0.5 0.006 15.6 0.0 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 CAR30234.1 - 0.0013 18.3 0.0 0.091 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CAR30234.1 - 0.0021 17.5 0.0 0.0051 16.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAR30234.1 - 0.0041 16.3 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CAR30234.1 - 0.051 13.8 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 CAR30234.1 - 0.072 12.2 0.0 2.2 7.4 0.0 2.6 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_29 PF13555.1 CAR30234.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CAR30234.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Nup96 PF12110.3 CAR30235.1 - 3e-48 164.3 0.5 5.4e-48 163.5 0.3 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CAR30235.1 - 1.4e-46 157.8 0.0 3.1e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CAR30235.1 - 6.5e-08 32.7 69.0 1.3e-05 25.3 26.6 4.8 2 1 2 4 4 4 2 Nucleoporin FG repeat region Spc7 PF08317.6 CAR30236.1 - 5.5e-63 212.5 4.3 1.1e-62 211.6 2.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Ribosomal_L36 PF00444.13 CAR30237.1 - 4e-20 71.5 9.7 4.8e-20 71.2 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 CAR30237.1 - 0.0026 17.0 1.5 0.0034 16.6 1.1 1.1 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family CENP-F_C_Rb_bdg PF10490.4 CAR30237.1 - 0.16 11.3 0.2 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 WD40 PF00400.27 CAR30238.1 - 2.1e-19 68.5 20.9 3.3e-06 26.7 0.2 9.5 10 0 0 10 10 10 6 WD domain, G-beta repeat UCH_1 PF13423.1 CAR30239.1 - 3.8e-54 184.1 0.2 5.3e-54 183.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CAR30239.1 - 3e-22 79.6 0.0 7.3e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 CAR30239.1 - 2.1e-07 30.3 0.9 7.9e-07 28.4 0.6 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TCO89 PF10452.4 CAR30240.1 - 2.2e-129 433.1 54.4 2.9e-129 432.7 37.7 1.1 1 0 0 1 1 1 1 TORC1 subunit TCO89 Sec1 PF00995.18 CAR30241.1 - 1.2e-130 436.9 6.3 1.3e-130 436.7 4.4 1.0 1 0 0 1 1 1 1 Sec1 family PHD PF00628.24 CAR30242.1 - 2.7e-11 42.9 6.5 5.1e-11 42.0 4.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CAR30242.1 - 0.0024 17.1 4.5 0.0041 16.3 3.1 1.4 1 0 0 1 1 1 1 PHD-finger Metallophos PF00149.23 CAR30243.1 - 5.9e-40 136.8 0.0 8.6e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SR-25 PF10500.4 CAR30243.1 - 3.7 6.9 6.6 6.1 6.2 4.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.17 CAR30244.1 - 1.7e-15 56.3 0.0 2.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR30244.1 - 1.9e-11 43.7 0.0 3.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR30244.1 - 4.4e-08 32.8 0.0 7.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox_KN PF05920.6 CAR30245.1 - 1.4e-17 63.1 0.2 3.3e-17 61.8 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CAR30245.1 - 1.3e-06 27.8 0.2 3.6e-06 26.5 0.2 1.8 1 0 0 1 1 1 1 Homeobox domain UPF0560 PF10577.4 CAR30245.1 - 0.11 10.7 5.0 0.19 9.9 3.4 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.4 CAR30245.1 - 0.37 8.9 9.7 0.37 8.9 6.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Calpain_inhib PF00748.14 CAR30245.1 - 0.43 10.9 3.4 1 9.7 0.3 2.5 1 1 1 2 2 2 0 Calpain inhibitor Arrestin_N PF00339.24 CAR30246.1 - 6e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sugar_tr PF00083.19 CAR30247.1 - 3.3e-82 276.4 20.6 4e-82 276.1 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30247.1 - 1.2e-12 47.2 26.0 1.2e-12 47.2 18.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CAR30247.1 - 1.3e-05 23.8 18.6 0.0023 16.3 4.8 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein FPN1 PF06963.7 CAR30247.1 - 1.3 7.3 11.0 0.033 12.5 3.0 1.6 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Alpha-amylase PF00128.19 CAR30248.1 - 4.9e-98 328.4 0.0 6.7e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DAHP_synth_1 PF00793.15 CAR30249.1 - 8.8e-106 352.5 0.0 1.1e-105 352.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family His_biosynth PF00977.16 CAR30250.1 - 8.7e-46 156.0 0.2 6.9e-45 153.0 0.2 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein GATase PF00117.23 CAR30250.1 - 3.6e-30 104.8 0.0 6.4e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CAR30250.1 - 3.4e-07 29.9 0.0 7.2e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 CAR30250.1 - 5.8e-06 26.0 0.0 0.0068 16.0 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 CAR30250.1 - 0.0012 18.3 0.3 0.011 15.1 0.2 2.1 1 1 0 1 1 1 1 Peptidase C26 ThiG PF05690.9 CAR30250.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG RCC1 PF00415.13 CAR30251.1 - 1.7e-65 216.9 0.0 4.1e-14 52.5 0.1 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CAR30251.1 - 3.9e-44 147.3 18.4 2.3e-10 39.7 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.1 CAR30251.1 - 0.032 14.0 0.3 26 4.5 0.0 3.8 4 0 0 4 4 4 0 SUKH-3 immunity protein PSK_trans_fac PF07704.6 CAR30252.1 - 0.12 13.0 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Rv0623-like transcription factor Bystin PF05291.6 CAR30253.1 - 3.1e-123 410.5 0.0 6.9e-123 409.4 0.0 1.5 1 1 0 1 1 1 1 Bystin BTV_NS2 PF04514.7 CAR30253.1 - 9.5 4.9 18.0 14 4.4 12.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MFS_1 PF07690.11 CAR30254.1 - 5.1e-34 117.5 36.9 5.1e-34 117.5 25.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CAR30254.1 - 5.6e-10 38.3 9.7 5.6e-10 38.3 6.7 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter Use1 PF09753.4 CAR30255.1 - 1.1e-08 34.8 2.8 2.7e-08 33.5 1.9 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 ArsR PF09824.4 CAR30255.1 - 0.11 11.8 0.0 0.91 8.8 0.0 2.1 2 0 0 2 2 2 0 ArsR transcriptional regulator DUF1980 PF09323.5 CAR30255.1 - 5.4 6.7 6.2 0.72 9.5 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Peptidase_M20 PF01546.23 CAR30256.1 - 1.1e-20 73.9 0.0 1.7e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR30256.1 - 1.8e-11 43.7 0.0 4.6e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain FMN_bind PF04205.9 CAR30256.1 - 0.11 12.6 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 FMN-binding domain S6PP PF05116.8 CAR30256.1 - 0.16 11.2 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase MMR_HSR1 PF01926.18 CAR30257.1 - 5.3e-17 61.8 0.2 5.6e-15 55.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CAR30257.1 - 4e-09 35.9 0.3 5.7e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 CAR30257.1 - 0.0004 19.6 0.0 0.00076 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CAR30257.1 - 0.0077 16.0 2.0 0.02 14.6 0.7 2.5 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.11 CAR30257.1 - 0.0081 15.2 0.1 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CAR30257.1 - 0.011 16.1 0.3 0.077 13.4 0.1 2.3 2 0 0 2 2 2 0 Miro-like protein MCR_alpha PF02249.12 CAR30257.1 - 0.054 13.5 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain AAA_18 PF13238.1 CAR30257.1 - 0.58 10.4 3.8 9.5 6.5 0.0 4.0 4 1 0 4 4 4 0 AAA domain WD40 PF00400.27 CAR30258.1 - 1e-06 28.3 5.9 0.65 9.9 0.2 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat SNF2_N PF00176.18 CAR30259.1 - 1e-80 270.7 0.6 1e-80 270.7 0.4 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 CAR30259.1 - 1.3e-40 137.8 1.6 1.3e-40 137.8 1.1 2.4 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 CAR30259.1 - 7.3e-30 103.6 2.2 7.3e-30 103.6 1.5 3.4 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 CAR30259.1 - 8e-16 57.6 0.0 4.2e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CAR30259.1 - 1.2e-11 44.0 0.1 5e-11 41.9 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CAR30259.1 - 1.1e-09 38.3 3.3 8.8e-09 35.4 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR30259.1 - 1.2e-06 28.1 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 CAR30259.1 - 0.00094 18.6 0.1 0.0021 17.5 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.1 CAR30259.1 - 0.007 16.2 0.6 0.044 13.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain GSHPx PF00255.14 CAR30260.1 - 3.3e-46 155.1 0.1 4.2e-46 154.7 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CAR30260.1 - 5.2e-06 26.1 0.1 1.8e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CAR30260.1 - 1.5e-05 24.5 0.0 4.1e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 CAR30260.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) WD40 PF00400.27 CAR30261.1 - 1.7e-33 113.2 15.9 3.8e-09 36.0 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat YmzC PF14157.1 CAR30261.1 - 0.016 15.0 0.0 0.41 10.4 0.0 3.0 4 0 0 4 4 4 0 YmzC-like protein Apc4_WD40 PF12894.2 CAR30261.1 - 0.079 12.4 0.4 23 4.6 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glycos_transf_4 PF00953.16 CAR30262.1 - 5.9e-29 100.9 12.5 5.9e-29 100.9 8.7 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 VKG_Carbox PF05090.9 CAR30262.1 - 0.15 10.8 5.2 0.027 13.3 0.9 1.6 1 1 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase HD_3 PF13023.1 CAR30263.1 - 1.2e-37 129.1 0.1 1.6e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 CAR30263.1 - 3.3e-06 27.1 1.5 1.3e-05 25.1 1.0 1.9 1 1 0 1 1 1 1 HD domain Ribosomal_L18e PF00828.14 CAR30264.1 - 2.7e-34 118.3 0.1 3.7e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Sugar_tr PF00083.19 CAR30265.1 - 2.5e-98 329.6 11.9 5.4e-97 325.2 8.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30265.1 - 5.6e-36 123.9 16.0 8.4e-36 123.4 11.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CAR30265.1 - 1.3e-09 36.7 1.4 1.3e-09 36.7 1.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 CAR30265.1 - 5.2e-05 21.8 0.1 5.2e-05 21.8 0.1 3.8 2 2 2 4 4 4 4 MFS/sugar transport protein Zn_clus PF00172.13 CAR30266.1 - 4.4e-11 42.5 6.3 1.3e-10 40.9 4.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 CAR30266.1 - 0.096 10.7 7.1 0.12 10.4 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein tRNA_bind PF01588.15 CAR30267.1 - 1.8e-28 98.1 0.0 3.7e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Suf PF05843.9 CAR30267.1 - 4.6 6.8 8.6 8.4 6.0 6.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAS PF00989.19 CAR30268.1 - 3.3e-14 52.6 0.0 6.9e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 CAR30268.1 - 7.7e-08 32.1 10.3 1.4e-07 31.2 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CpeT PF06206.6 CAR30268.1 - 0.049 13.2 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) EF-hand_7 PF13499.1 CAR30269.1 - 6.5e-13 48.6 0.3 1.9e-07 31.0 0.2 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CAR30269.1 - 2e-09 36.5 3.9 0.00087 18.9 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CAR30269.1 - 6.1e-09 34.5 5.2 0.00074 18.6 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CAR30269.1 - 4.1e-08 33.0 0.0 0.0049 16.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CAR30269.1 - 1.2e-06 28.0 2.3 0.0012 18.4 0.2 3.6 3 1 1 4 4 4 2 EF-hand domain pair Caleosin PF05042.8 CAR30269.1 - 0.072 12.6 0.1 6.1 6.3 0.0 2.4 1 1 1 2 2 2 0 Caleosin related protein Transcrip_act PF04949.8 CAR30269.1 - 0.092 12.3 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional activator FliG_N PF14842.1 CAR30269.1 - 0.094 12.8 0.2 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Med15_fungi PF05397.7 CAR30269.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Mediator complex subunit 15 UPF0154 PF03672.8 CAR30269.1 - 0.14 11.7 0.0 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 CAR30269.1 - 3.6 7.0 6.6 2.1 7.8 0.1 2.9 3 0 0 3 3 3 0 EF hand Flagellin_N PF00669.15 CAR30271.1 - 0.025 14.3 1.4 0.034 13.9 0.5 1.4 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region DEAD PF00270.24 CAR30272.1 - 1.4e-44 151.6 0.0 2.7e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30272.1 - 3.1e-19 68.6 0.0 7.6e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CAR30272.1 - 0.00019 20.3 0.0 0.00039 19.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 CAR30272.1 - 0.0042 17.0 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain Pox_MCEL PF03291.11 CAR30273.1 - 6e-97 324.4 0.1 6e-97 324.4 0.0 1.8 2 0 0 2 2 2 1 mRNA capping enzyme Methyltransf_12 PF08242.7 CAR30273.1 - 4.8e-09 36.5 0.1 1.8e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR30273.1 - 9.4e-09 35.1 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR30273.1 - 2.7e-07 31.1 0.0 5.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR30273.1 - 4e-07 30.4 0.0 8.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR30273.1 - 5.2e-06 26.1 0.5 1.4e-05 24.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR30273.1 - 3.8e-05 23.9 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CAR30273.1 - 0.0086 15.0 0.4 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Hom_end_hint PF05203.11 CAR30273.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.3 1 1 0 1 1 1 0 Hom_end-associated Hint Methyltransf_4 PF02390.12 CAR30273.1 - 0.014 14.4 0.0 0.014 14.4 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.15 CAR30273.1 - 0.023 13.8 0.0 0.062 12.3 0.0 1.7 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CAR30273.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Merozoite_SPAM PF07133.6 CAR30273.1 - 0.057 13.3 9.5 0.096 12.5 6.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Mnd1 PF03962.10 CAR30273.1 - 0.74 9.4 11.6 1.3 8.6 8.0 1.3 1 0 0 1 1 1 0 Mnd1 family CCDC71L PF15374.1 CAR30273.1 - 2.2 7.5 7.9 2.9 7.1 5.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L AA_permease PF00324.16 CAR30274.1 - 3.1e-48 164.3 36.8 4.2e-48 163.8 25.5 1.2 1 0 0 1 1 1 1 Amino acid permease CUE PF02845.11 CAR30275.1 - 2.2e-10 39.8 0.0 3.3e-09 36.0 0.0 2.5 1 1 1 2 2 2 1 CUE domain UBA_4 PF14555.1 CAR30275.1 - 0.0084 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain WD40 PF00400.27 CAR30277.1 - 4.9e-15 54.7 14.8 1.9e-05 24.3 0.4 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 CAR30277.1 - 0.012 15.3 1.0 0.1 12.3 0.0 2.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 CAR30277.1 - 0.12 11.5 0.3 0.21 10.7 0.2 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DASH_Dad3 PF08656.5 CAR30278.1 - 2.7e-26 91.0 0.3 2.8e-26 90.9 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Cep57_MT_bd PF06657.8 CAR30278.1 - 0.048 13.5 0.1 0.062 13.2 0.1 1.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 PilJ PF13675.1 CAR30278.1 - 0.1 12.9 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1546 PF07571.8 CAR30279.1 - 4.9e-32 109.8 0.0 1.2e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 CAR30279.1 - 8.4e-28 96.1 0.4 1.6e-27 95.2 0.3 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CAR30279.1 - 0.00043 20.3 0.3 0.0012 18.9 0.2 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CAR30279.1 - 0.0037 17.3 0.5 0.0099 15.9 0.2 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 CAR30279.1 - 0.012 15.4 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 CAR30279.1 - 0.03 14.5 0.4 0.13 12.4 0.1 2.2 2 0 0 2 2 2 0 Kinetochore component CENP-S TAF4 PF05236.9 CAR30279.1 - 0.042 13.1 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CLASP_N PF12348.3 CAR30279.1 - 0.081 12.2 0.1 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 CLASP N terminal SLD3 PF08639.5 CAR30280.1 - 7.3e-62 209.6 25.4 1.2e-60 205.5 17.6 2.1 1 1 0 1 1 1 1 DNA replication regulator SLD3 KH_1 PF00013.24 CAR30281.1 - 1.2e-35 120.9 7.1 8.4e-14 50.9 1.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CAR30281.1 - 1.9e-28 97.5 11.5 3.7e-11 42.3 2.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CAR30281.1 - 2e-10 40.0 2.2 0.019 14.5 0.1 3.7 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 CAR30281.1 - 5.5e-07 29.1 1.1 0.043 13.4 0.0 2.8 2 1 1 3 3 3 2 KH domain KH_5 PF13184.1 CAR30281.1 - 0.011 15.4 1.7 26 4.6 0.1 3.5 3 0 0 3 3 3 0 NusA-like KH domain NAD_kinase PF01513.16 CAR30281.1 - 0.083 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase BCNT PF07572.7 CAR30282.1 - 4.8e-25 87.3 0.3 4.8e-25 87.3 0.2 2.5 3 1 0 3 3 3 1 Bucentaur or craniofacial development OPT PF03169.10 CAR30283.1 - 1.7e-148 495.8 16.2 1.9e-148 495.7 11.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PsaM PF07465.8 CAR30283.1 - 0.1 12.2 4.8 0.27 10.8 3.3 1.7 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) DUF4229 PF14012.1 CAR30283.1 - 5.9 6.8 11.5 6.8 6.6 4.5 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) CBS PF00571.23 CAR30284.1 - 1.4e-31 108.0 1.9 2e-13 49.8 0.0 4.3 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.6 CAR30284.1 - 0.27 11.1 1.9 2.4 8.1 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain WD40 PF00400.27 CAR30285.1 - 9.5e-23 79.2 9.0 8.8e-08 31.7 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CAR30285.1 - 2.1e-05 24.3 0.6 0.024 14.3 0.0 3.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ABC1 PF03109.11 CAR30286.1 - 2.3e-36 124.3 0.0 1.4e-35 121.8 0.0 2.2 2 0 0 2 2 2 1 ABC1 family TPR_6 PF13174.1 CAR30286.1 - 0.21 12.1 0.8 31 5.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HA2 PF04408.18 CAR30287.1 - 6.9e-26 90.2 0.0 6.9e-26 90.2 0.0 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CAR30287.1 - 6.4e-25 87.2 0.0 1.6e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CAR30287.1 - 2.9e-11 43.0 0.0 6.7e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CAR30287.1 - 1.7e-08 34.1 0.4 2.9e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CAR30287.1 - 1.5e-05 25.1 0.0 6.9e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CAR30287.1 - 4.6e-05 22.9 0.2 0.00012 21.6 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 CAR30287.1 - 0.00025 20.8 0.3 0.00053 19.7 0.2 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 CAR30287.1 - 0.00063 19.6 0.0 0.42 10.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CAR30287.1 - 0.013 15.8 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CAR30287.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CAR30287.1 - 0.026 13.4 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CAR30287.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 CAR30287.1 - 0.078 12.1 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Nab2 PF11517.3 CAR30288.1 - 7.6e-40 135.3 0.1 1.4e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 CAR30288.1 - 7.1e-14 51.1 66.9 7.2e-05 22.6 4.5 7.0 7 0 0 7 7 7 5 Zinc finger C-x8-C-x5-C-x3-H type PAT1 PF09770.4 CAR30288.1 - 0.0085 14.3 12.7 0.014 13.6 8.8 1.4 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF2508 PF10704.4 CAR30288.1 - 0.019 15.1 0.0 0.019 15.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Ribosomal_S5 PF00333.15 CAR30289.1 - 1.3e-28 98.5 3.0 1.3e-28 98.5 2.1 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CAR30289.1 - 3.9e-22 77.3 0.1 6.5e-22 76.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Vma12 PF11712.3 CAR30290.1 - 0.0013 18.4 0.2 0.0018 17.9 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF883 PF05957.8 CAR30290.1 - 0.004 17.5 8.6 0.081 13.3 0.8 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Alk_phosphatase PF00245.15 CAR30290.1 - 0.0077 14.9 0.1 0.0099 14.6 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase DUF3773 PF12608.3 CAR30290.1 - 0.047 13.7 0.6 0.096 12.7 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3773) Prominin PF05478.6 CAR30290.1 - 0.12 9.8 0.5 0.15 9.5 0.3 1.1 1 0 0 1 1 1 0 Prominin Mon1 PF03164.9 CAR30291.1 - 1.1e-113 379.9 4.7 1.2e-112 376.5 0.4 3.0 2 1 0 2 2 2 1 Trafficking protein Mon1 TMEM156 PF15106.1 CAR30291.1 - 0.066 12.4 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 TMEM156 protein family GATA PF00320.22 CAR30292.1 - 3.2e-14 51.9 6.7 5.9e-14 51.1 4.7 1.5 1 0 0 1 1 1 1 GATA zinc finger Glyco_hydro_31 PF01055.21 CAR30293.1 - 9.7e-147 489.3 0.1 1.3e-146 488.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CAR30293.1 - 2.2e-20 72.2 0.0 7.2e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like GIY-YIG PF01541.19 CAR30294.1 - 1.1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 CAR30294.1 - 0.0039 17.5 0.2 0.048 14.0 0.1 2.5 1 1 0 1 1 1 1 T5orf172 domain zf-RING_2 PF13639.1 CAR30294.1 - 0.0071 16.1 8.7 0.067 13.0 3.3 2.7 2 1 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 CAR30294.1 - 0.02 14.8 4.8 0.049 13.5 3.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain DUF4451 PF14616.1 CAR30294.1 - 0.062 13.0 4.6 0.6 9.8 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4451) DUF2256 PF10013.4 CAR30294.1 - 0.23 11.2 1.9 6.5 6.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.1 CAR30294.1 - 1.3 9.4 6.1 4.4 7.7 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain DUF329 PF03884.9 CAR30294.1 - 2.7 7.6 7.5 11 5.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF329) zf-C3HC4_3 PF13920.1 CAR30294.1 - 2.8 7.6 6.8 21 4.8 4.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 CAR30294.1 - 8.2 7.0 8.5 2.9 8.4 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type AAA_2 PF07724.9 CAR30295.1 - 1e-34 119.9 1.6 1.8e-34 119.1 0.2 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CAR30295.1 - 4.8e-13 49.4 0.1 1.1e-12 48.2 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CAR30295.1 - 4.2e-08 32.9 0.2 1.3e-07 31.4 0.0 1.9 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.1 CAR30295.1 - 6.7e-06 26.2 0.1 7.8e-05 22.8 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CAR30295.1 - 6.9e-06 25.8 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CAR30295.1 - 1.6e-05 24.9 0.4 0.00061 19.8 0.2 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CAR30295.1 - 3.9e-05 24.4 0.8 0.0001 23.1 0.0 2.3 3 0 0 3 3 1 1 AAA domain Mg_chelatase PF01078.16 CAR30295.1 - 8.9e-05 21.7 0.0 0.0094 15.1 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CAR30295.1 - 0.00067 19.1 0.1 0.1 12.0 0.0 3.2 2 1 0 3 3 3 1 Sigma-54 interaction domain RuvB_N PF05496.7 CAR30295.1 - 0.0016 17.5 0.0 0.0053 15.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CAR30295.1 - 0.002 18.0 0.0 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CAR30295.1 - 0.0034 16.8 0.0 0.0086 15.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CAR30295.1 - 0.004 17.0 0.1 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CAR30295.1 - 0.0061 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CAR30295.1 - 0.0072 16.0 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 CAR30295.1 - 0.0083 15.8 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DEAD PF00270.24 CAR30295.1 - 0.013 15.0 0.1 0.11 11.9 0.1 2.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase ABC_tran PF00005.22 CAR30295.1 - 0.016 15.4 0.4 0.048 13.9 0.3 2.1 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CAR30295.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CAR30295.1 - 0.035 13.0 0.2 0.078 11.8 0.1 1.7 1 1 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 CAR30295.1 - 0.036 13.3 0.0 0.087 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 CAR30295.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 CAR30295.1 - 0.068 13.3 0.1 0.43 10.7 0.0 2.4 3 0 0 3 3 2 0 RNA helicase AAA_25 PF13481.1 CAR30295.1 - 0.086 12.2 0.2 0.25 10.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CAR30295.1 - 0.088 12.2 0.2 0.26 10.6 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain DUF3987 PF13148.1 CAR30295.1 - 0.094 11.2 1.6 4.7 5.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) AAA_18 PF13238.1 CAR30295.1 - 0.1 12.9 2.3 0.3 11.3 0.2 2.6 2 1 0 2 2 2 0 AAA domain Methyltransf_11 PF08241.7 CAR30296.1 - 0.0026 18.2 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR30296.1 - 0.033 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTHFR PF02219.12 CAR30297.1 - 1.1e-121 405.4 0.0 1.5e-121 404.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Tyr-DNA_phospho PF06087.7 CAR30298.1 - 2.7e-97 326.2 0.0 3.1e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase AMP-binding PF00501.23 CAR30299.1 - 1.2e-71 241.3 0.0 1.5e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CAR30299.1 - 1.4e-16 61.1 0.0 3.2e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Transket_pyr PF02779.19 CAR30300.1 - 6.6e-47 159.2 0.0 1.5e-46 158.1 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CAR30300.1 - 3.9e-35 120.4 0.1 7.6e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PSK_trans_fac PF07704.6 CAR30300.1 - 0.081 13.6 0.2 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Rv0623-like transcription factor Acatn PF13000.2 CAR30301.1 - 1.7e-205 683.7 16.3 2e-205 683.4 11.3 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Scs3p PF10261.4 CAR30302.1 - 4.8e-66 222.2 12.4 6.6e-66 221.7 8.6 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Med31 PF05669.7 CAR30303.1 - 1.8e-32 111.1 0.2 2.3e-32 110.7 0.1 1.1 1 0 0 1 1 1 1 SOH1 CPSase_L_D2 PF02786.12 CAR30304.1 - 3.5e-84 281.3 0.2 5.6e-84 280.6 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CAR30304.1 - 1.1e-65 220.8 0.0 1.8e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CAR30304.1 - 7.6e-36 122.5 0.0 2.1e-35 121.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CAR30304.1 - 7.4e-31 106.3 0.0 4e-30 103.9 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CAR30304.1 - 4.4e-27 95.2 0.0 8.2e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 CAR30304.1 - 1.8e-21 76.2 0.0 2.2e-20 72.6 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CAR30304.1 - 6.4e-20 70.5 8.1 7.8e-20 70.2 1.8 3.0 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CAR30304.1 - 1.9e-17 63.6 0.1 3.7e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CAR30304.1 - 1.7e-11 43.5 2.3 4.1e-05 23.1 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CAR30304.1 - 1.4e-08 34.3 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CAR30304.1 - 1.6e-07 30.8 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CAR30304.1 - 2.5e-06 27.1 0.0 7.8e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CAR30304.1 - 6.8e-06 26.0 0.0 1.8e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CAR30304.1 - 0.00012 21.4 0.7 0.018 14.3 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 CAR30304.1 - 0.00066 19.3 2.7 0.02 14.5 0.2 2.8 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.2 CAR30304.1 - 0.0012 18.1 0.3 0.52 9.4 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 CAR30304.1 - 0.0027 18.0 0.2 1 9.7 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein Serine_rich PF08824.5 CAR30304.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain DASH_Duo1 PF08651.5 CAR30305.1 - 6e-25 86.6 0.8 6e-25 86.6 0.5 2.0 2 0 0 2 2 2 1 DASH complex subunit Duo1 Glutaredoxin2_C PF04399.8 CAR30305.1 - 0.33 10.5 2.9 0.29 10.6 0.5 1.9 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain IncA PF04156.9 CAR30305.1 - 2.2 7.8 8.7 5.8 6.4 6.0 1.6 1 1 0 1 1 1 0 IncA protein SseC PF04888.7 CAR30305.1 - 8.2 5.6 8.1 19 4.4 3.1 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family APG12 PF04110.8 CAR30306.1 - 7.6e-27 93.3 0.0 1.2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Kinetochor_Ybp2 PF08568.5 CAR30307.1 - 2.7e-146 488.4 15.7 3.4e-146 488.1 10.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.5 CAR30308.1 - 1e-13 50.9 0.0 3.2e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain BCDHK_Adom3 PF10436.4 CAR30309.1 - 3.9e-34 117.5 1.9 4.2e-34 117.4 0.6 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CAR30309.1 - 9.9e-10 38.1 0.0 1.4e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CAR30309.1 - 0.029 14.0 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.21 CAR30310.1 - 3.8e-48 162.4 0.1 4.8e-48 162.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CAR30310.1 - 4.4e-06 26.4 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CAR30310.1 - 0.022 14.6 0.3 0.068 13.0 0.2 1.8 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 CAR30310.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain CBS PF00571.23 CAR30312.1 - 1.3e-19 69.7 1.2 5.2e-05 22.9 0.0 5.3 5 0 0 5 5 5 5 CBS domain FA_desaturase PF00487.19 CAR30313.1 - 2.6e-20 72.9 19.0 2.6e-20 72.9 13.2 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CAR30313.1 - 4.1e-14 52.1 0.0 8.4e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_7 PF13241.1 CAR30314.1 - 1.1e-26 93.0 0.0 2.6e-26 91.8 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CAR30314.1 - 3.1e-17 61.6 0.0 6.4e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CAR30314.1 - 9.1e-16 56.5 0.3 1.7e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 CAR30314.1 - 0.0044 17.1 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 CAR30314.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.17 CAR30315.1 - 5.7e-41 137.9 0.0 1.2e-16 60.0 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR30315.1 - 3.1e-27 94.3 0.0 2.6e-11 43.3 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR30315.1 - 2.4e-23 81.7 0.0 2.3e-11 43.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neur_chan_memb PF02932.11 CAR30315.1 - 0.013 15.4 1.0 0.013 15.4 0.7 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.1 CAR30315.1 - 0.014 13.1 24.7 0.02 12.6 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nup35_RRM_2 PF14605.1 CAR30315.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Zip PF02535.17 CAR30315.1 - 0.034 13.1 8.7 0.048 12.6 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 CAR30315.1 - 0.049 11.9 6.7 0.065 11.5 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein RRM_3 PF08777.6 CAR30315.1 - 0.082 12.7 1.0 0.25 11.1 0.0 2.2 2 1 0 2 2 2 0 RNA binding motif DUF3595 PF12166.3 CAR30315.1 - 0.12 11.2 3.0 0.16 10.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Suf PF05843.9 CAR30315.1 - 0.12 12.0 8.0 0.2 11.3 5.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4613 PF15390.1 CAR30315.1 - 0.95 7.5 10.1 1.3 7.0 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF4557 PF15101.1 CAR30315.1 - 1.2 8.9 13.3 1.9 8.2 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Mnd1 PF03962.10 CAR30315.1 - 6.7 6.3 17.5 11 5.6 12.1 1.2 1 0 0 1 1 1 0 Mnd1 family DUF3450 PF11932.3 CAR30315.1 - 7.6 5.7 20.8 12 5.0 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TFIIA PF03153.8 CAR30315.1 - 9.1 6.0 22.2 0.3 10.9 11.2 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tho2 PF11262.3 CAR30315.1 - 9.7 5.1 11.1 16 4.3 7.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2967 PF11179.3 CAR30316.1 - 0.032 13.7 0.6 0.032 13.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) CHASE3 PF05227.8 CAR30316.1 - 1.2 8.7 8.0 2.6 7.7 4.7 2.1 1 1 1 2 2 2 0 CHASE3 domain Cornichon PF03311.9 CAR30317.1 - 5.5e-50 168.8 10.5 6.1e-50 168.6 7.3 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 CAR30317.1 - 0.0081 15.7 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1634) TAS2R PF05296.8 CAR30317.1 - 0.043 12.7 7.0 0.05 12.4 4.9 1.1 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) SNF2_N PF00176.18 CAR30319.1 - 1.3e-67 227.7 0.9 1.3e-67 227.7 0.6 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR30319.1 - 2.9e-11 43.0 0.0 8.7e-11 41.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 CAR30319.1 - 6e-08 32.5 2.1 1.9e-07 30.9 1.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CAR30319.1 - 9.7e-07 28.3 4.1 2.1e-06 27.2 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CAR30319.1 - 5.3e-06 26.1 4.1 1.1e-05 25.1 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CAR30319.1 - 3.4e-05 23.4 3.8 7.5e-05 22.3 2.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 CAR30319.1 - 5e-05 23.2 0.5 0.00037 20.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR30319.1 - 0.00075 19.0 1.0 0.0067 15.9 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 CAR30319.1 - 0.00079 19.0 3.8 0.0018 17.8 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CAR30319.1 - 0.0013 18.3 0.9 0.0044 16.6 0.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 CAR30319.1 - 0.32 10.6 2.7 0.69 9.5 1.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CAR30319.1 - 1.1 9.2 5.8 2.3 8.1 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cellulase PF00150.13 CAR30320.1 - 6.9e-15 55.0 0.1 1.2e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1754 PF08555.5 CAR30321.1 - 3.8 8.1 13.6 0.36 11.4 6.2 1.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PBP_sp32 PF07222.7 CAR30321.1 - 9.1 5.3 11.0 4.6 6.3 6.4 1.2 1 1 0 1 1 1 0 Proacrosin binding protein sp32 DUF1708 PF08101.6 CAR30323.1 - 2.5e-149 497.7 5.3 4.5e-149 496.8 3.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 CAR30323.1 - 0.00093 18.8 0.0 0.0047 16.5 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain G_glu_transpept PF01019.16 CAR30324.1 - 2.8e-134 448.4 0.0 3.3e-134 448.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GTP_EFTU PF00009.22 CAR30325.1 - 1.1e-61 207.5 0.8 1.5e-61 207.1 0.5 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CAR30325.1 - 1.4e-27 95.7 0.0 3.4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CAR30325.1 - 1.1e-19 70.2 1.1 3.3e-19 68.7 0.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CAR30325.1 - 1.9e-05 24.5 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CAR30325.1 - 3.2e-05 23.4 0.2 7.2e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CAR30325.1 - 0.00063 20.2 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CAR30325.1 - 0.02 14.4 1.4 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CAR30325.1 - 0.026 13.9 0.1 0.026 13.9 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-U1 PF06220.7 CAR30326.1 - 3.8e-16 58.3 2.3 8.4e-16 57.2 1.6 1.6 1 0 0 1 1 1 1 U1 zinc finger Stn1 PF10451.4 CAR30327.1 - 7.3e-43 146.2 0.0 1e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 CAR30327.1 - 6e-42 142.4 0.0 1e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH Acetyltransf_6 PF13480.1 CAR30327.1 - 5.7 6.8 8.5 8.4 6.3 0.4 3.3 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Transthyretin PF00576.16 CAR30328.1 - 1.3e-30 105.5 0.3 8.3e-21 73.9 0.8 2.1 1 1 1 2 2 2 2 HIUase/Transthyretin family DDE_1 PF03184.14 CAR30329.1 - 1.4e-70 236.8 2.1 2.4e-70 236.0 1.5 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CAR30329.1 - 1e-14 54.0 0.1 2.5e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.1 CAR30329.1 - 0.085 13.6 0.1 0.35 11.7 0.1 2.1 1 0 0 1 1 1 0 Homeodomain-like domain Clathrin PF00637.15 CAR30330.1 - 1.1e-22 80.1 3.0 7.1e-22 77.5 0.1 2.8 2 1 1 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.4 CAR30330.1 - 7.4e-05 22.7 0.5 0.00032 20.6 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.27 CAR30330.1 - 0.042 13.7 1.4 0.15 11.9 1.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat CENP-B_dimeris PF09026.5 CAR30330.1 - 0.11 12.7 10.0 0.36 11.0 6.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myc_N PF01056.13 CAR30330.1 - 1.2 8.2 9.6 2 7.5 6.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 CAR30330.1 - 7.1 4.4 18.0 10 3.8 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.8 CAR30330.1 - 7.1 4.2 19.8 10 3.7 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sec34 PF04136.10 CAR30331.1 - 7.4e-22 77.7 5.5 7.4e-22 77.7 3.8 3.1 3 1 0 4 4 4 1 Sec34-like family Exo70 PF03081.10 CAR30331.1 - 0.0027 16.5 0.3 0.0027 16.5 0.2 3.9 5 1 0 5 5 5 2 Exo70 exocyst complex subunit Laminin_II PF06009.7 CAR30331.1 - 0.0051 16.5 1.3 5.5 6.7 0.0 3.5 3 0 0 3 3 3 2 Laminin Domain II Sod_Fe_N PF00081.17 CAR30331.1 - 0.087 13.0 2.5 0.31 11.3 0.0 3.1 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF1947 PF09183.5 CAR30332.1 - 0.12 12.2 0.5 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Cwf_Cwc_15 PF04889.7 CAR30332.1 - 1.4 8.5 6.0 1.8 8.1 4.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2346 PF09803.4 CAR30332.1 - 4.3 7.2 6.0 26 4.7 4.2 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) UPF0160 PF03690.8 CAR30333.1 - 1.9e-125 418.5 0.0 2.2e-125 418.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF2186 PF09952.4 CAR30333.1 - 0.15 12.2 0.0 1.2 9.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2186) RhoGAP PF00620.22 CAR30334.1 - 3.6e-37 127.3 0.0 1.1e-36 125.6 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CAR30334.1 - 1.8e-26 93.0 2.7 1.9e-26 92.9 0.1 2.4 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 CAR30334.1 - 9.6e-15 54.5 0.8 6.1e-14 51.9 0.1 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif 60KD_IMP PF02096.15 CAR30335.1 - 6.6e-38 130.3 0.5 6.6e-38 130.3 0.4 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein PET122 PF05476.6 CAR30336.1 - 4.3e-90 301.6 0.1 5.2e-90 301.3 0.1 1.0 1 0 0 1 1 1 1 PET122 M-factor PF03855.8 CAR30337.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 M-factor UCH PF00443.24 CAR30338.1 - 1.4e-53 181.7 5.2 3.7e-53 180.3 3.6 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR30338.1 - 1.3e-08 34.7 0.4 1.3e-08 34.7 0.3 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SelP_N PF04592.9 CAR30338.1 - 3.6 6.9 8.6 0.53 9.6 0.7 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region TAF4 PF05236.9 CAR30338.1 - 9.2 5.4 13.3 17 4.5 0.0 2.5 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Beta_helix PF13229.1 CAR30339.1 - 2.6 7.8 11.4 0.053 13.2 2.4 2.3 3 1 0 3 3 3 0 Right handed beta helix region DUF1236 PF06823.7 CAR30339.1 - 8 6.2 12.1 16 5.3 1.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1236) Toxin_9 PF02819.10 CAR30339.1 - 9.6 6.3 6.8 17 5.5 0.2 2.9 3 0 0 3 3 3 0 Spider toxin RecA PF00154.16 CAR30340.1 - 0.0066 15.5 0.0 0.0097 14.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CAR30340.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Rad51 PF08423.6 CAR30340.1 - 0.062 12.1 0.0 0.15 10.9 0.0 1.5 2 0 0 2 2 2 0 Rad51 Metallophos PF00149.23 CAR30341.1 - 1.1e-41 142.4 0.3 1.3e-41 142.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CAR30341.1 - 6.8e-05 22.7 0.0 9.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Filament PF00038.16 CAR30342.1 - 0.00091 18.7 9.8 0.023 14.1 0.2 2.9 3 0 0 3 3 3 2 Intermediate filament protein Nup54 PF13874.1 CAR30342.1 - 0.03 13.9 0.1 0.03 13.9 0.1 2.8 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DUF4200 PF13863.1 CAR30342.1 - 0.12 12.3 12.4 1 9.2 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) FliE PF02049.13 CAR30342.1 - 0.12 12.4 4.3 2.6 8.1 0.3 3.1 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE Seryl_tRNA_N PF02403.17 CAR30342.1 - 0.31 11.0 9.8 0.41 10.6 0.5 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4515 PF14988.1 CAR30342.1 - 0.46 10.1 13.1 0.048 13.3 1.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) CENP-Q PF13094.1 CAR30342.1 - 3.7 7.5 15.6 7.2 6.6 8.2 2.7 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF607 PF04678.8 CAR30342.1 - 4.2 7.2 5.9 0.65 9.9 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function, DUF607 NYD-SP28_assoc PF14775.1 CAR30342.1 - 5 6.9 8.0 4.8 6.9 0.0 3.4 3 0 0 3 3 3 0 Sperm tail C-terminal domain IncA PF04156.9 CAR30342.1 - 6.7 6.2 17.3 1.2 8.6 2.3 3.1 2 1 1 3 3 3 0 IncA protein TMF_TATA_bd PF12325.3 CAR30342.1 - 8.8 6.0 13.3 0.21 11.3 1.1 3.0 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TBP PF00352.16 CAR30343.1 - 4.2e-69 227.9 0.2 3.7e-35 119.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CAR30343.1 - 0.00026 20.9 0.1 0.58 10.2 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) Cohesin_load PF10345.4 CAR30344.1 - 1e-81 275.0 26.9 1.3e-81 274.6 18.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor Glyco_transf_20 PF00982.16 CAR30345.1 - 2.7e-142 474.6 0.3 3.8e-142 474.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CAR30345.1 - 3e-78 261.9 0.0 4.7e-78 261.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase MtrB PF05440.7 CAR30345.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B PAP2 PF01569.16 CAR30347.1 - 3.3e-09 36.5 1.8 3.3e-09 36.5 1.2 2.8 2 2 0 2 2 2 1 PAP2 superfamily PetL PF05115.9 CAR30347.1 - 9.3 6.2 7.2 21 5.0 1.4 3.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) LSM PF01423.17 CAR30348.1 - 1.1e-18 66.4 0.1 1.3e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAR30348.1 - 0.025 14.5 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Acetyltransf_1 PF00583.19 CAR30349.1 - 7.4e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR30349.1 - 2.7e-07 30.6 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CAR30349.1 - 6.2e-06 26.0 0.0 0.00018 21.3 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CAR30349.1 - 0.00096 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CAR30349.1 - 0.0046 16.6 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 CAR30349.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR30349.1 - 0.088 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UCH PF00443.24 CAR30351.1 - 1.3e-66 224.5 0.2 2.5e-66 223.5 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR30351.1 - 2.7e-28 99.2 0.1 8.7e-28 97.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CAR30351.1 - 4.5e-05 23.7 0.0 8.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.15 CAR30351.1 - 0.0021 17.5 1.5 0.0053 16.2 1.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger BSD PF03909.12 CAR30352.1 - 3.3e-12 45.9 1.5 3.3e-12 45.9 1.1 2.9 4 0 0 4 4 4 1 BSD domain Y_phosphatase2 PF03162.8 CAR30353.1 - 5.3e-56 188.5 0.4 6.5e-56 188.2 0.3 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CAR30353.1 - 0.02 14.4 0.1 0.033 13.7 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CAR30353.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Asp_protease PF09668.5 CAR30354.1 - 2.6e-53 178.8 0.9 4.6e-53 178.0 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.1 CAR30354.1 - 3.7e-12 46.5 0.1 7.7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 CAR30354.1 - 4.3e-09 35.9 0.0 1.2e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 CAR30354.1 - 8.9e-08 31.8 0.0 2.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CAR30354.1 - 1e-07 31.8 0.1 2.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CAR30354.1 - 1.6e-07 31.3 0.1 3.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease HhH-GPD PF00730.20 CAR30355.1 - 6.6e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF816 PF05674.7 CAR30355.1 - 0.14 11.8 1.1 0.67 9.6 0.1 2.4 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF816) DUF2239 PF09998.4 CAR30355.1 - 0.14 11.7 0.2 1.4 8.4 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) COX15-CtaA PF02628.10 CAR30356.1 - 5.6e-101 337.3 4.5 6.9e-101 337.0 3.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF747 PF05346.6 CAR30357.1 - 5.4e-91 305.0 17.6 7.9e-91 304.5 12.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family RPAP2_Rtr1 PF04181.8 CAR30358.1 - 1.8e-18 66.3 1.3 3.1e-18 65.6 0.9 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Syd PF07348.7 CAR30358.1 - 0.052 12.8 0.2 0.091 12.0 0.1 1.4 1 0 0 1 1 1 0 Syd protein (SUKH-2) DUF1002 PF06207.6 CAR30358.1 - 0.1 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF762 PF05555.6 CAR30358.1 - 0.11 11.6 0.7 2.5 7.2 0.1 2.1 2 0 0 2 2 2 0 Coxiella burnetii protein of unknown function (DUF762) Ribosomal_S13_N PF08069.7 CAR30360.1 - 2.6e-28 97.6 0.5 4.5e-28 96.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CAR30360.1 - 1.3e-23 82.5 0.2 5.4e-23 80.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 CAR30360.1 - 0.077 12.7 0.0 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 'Paired box' domain Cofilin_ADF PF00241.15 CAR30361.1 - 1e-09 38.3 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Aminotran_1_2 PF00155.16 CAR30362.1 - 3.7e-65 220.2 0.0 4.4e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 CAR30362.1 - 0.015 13.8 0.0 0.026 13.0 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 CAR30362.1 - 0.016 14.3 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 CAR30362.1 - 0.088 11.5 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Met_gamma_lyase PF06838.6 CAR30362.1 - 0.16 10.2 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase ABC_tran PF00005.22 CAR30363.1 - 6.9e-21 74.9 0.0 4.3e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CAR30363.1 - 1.1e-05 25.5 6.8 0.0022 17.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAR30363.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 CAR30363.1 - 0.025 14.4 0.1 0.076 12.9 0.0 1.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 CAR30363.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 CAR30363.1 - 0.13 12.4 0.2 2.1 8.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 CAR30363.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mannosyl_trans3 PF11051.3 CAR30364.1 - 1.3e-63 214.8 0.2 1.9e-63 214.3 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative GDI PF00996.13 CAR30365.1 - 1.1e-214 712.7 0.1 1.3e-214 712.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CAR30365.1 - 0.033 14.2 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CAR30365.1 - 0.11 11.3 0.0 0.62 8.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase LSM PF01423.17 CAR30366.1 - 2.5e-16 58.9 0.2 3.2e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CAR30366.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_60s PF00428.14 CAR30367.1 - 0.89 9.9 5.3 1.4 9.4 3.7 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein Myco_arth_vir_N PF09610.5 CAR30367.1 - 6.7 6.7 6.4 11 6.0 4.4 1.3 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) UAF_Rrn10 PF05234.6 CAR30368.1 - 5.3e-42 142.6 0.0 6e-42 142.4 0.0 1.0 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Nol1_Nop2_Fmu PF01189.12 CAR30369.1 - 2.7e-83 279.6 0.0 3.2e-66 223.5 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CAR30369.1 - 0.0021 18.0 0.1 0.0047 16.9 0.1 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CAR30369.1 - 0.0079 16.7 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MCM PF00493.18 CAR30370.1 - 2.4e-140 467.0 0.1 3.5e-140 466.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CAR30370.1 - 5e-29 101.3 29.1 5e-29 101.3 20.2 3.6 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CAR30370.1 - 1.4e-14 54.5 0.0 3.4e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CAR30370.1 - 5.4e-09 35.5 0.0 5.1e-07 29.0 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CAR30370.1 - 6.1e-08 32.4 0.0 1.5e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CAR30370.1 - 0.00019 21.0 0.0 0.0014 18.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAR30370.1 - 0.0017 17.8 0.1 0.012 15.0 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 CAR30370.1 - 0.0076 16.4 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-UBR PF02207.15 CAR30371.1 - 6.3e-13 48.2 13.6 6.3e-13 48.2 9.5 3.4 3 1 1 4 4 4 2 Putative zinc finger in N-recognin (UBR box) Aldedh PF00171.17 CAR30372.1 - 4.6e-157 523.0 0.0 5.3e-157 522.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CAR30372.1 - 0.002 17.3 0.0 0.046 12.9 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Lon_C PF05362.8 CAR30373.1 - 6.3e-66 221.5 0.0 1.7e-65 220.2 0.0 1.8 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CAR30373.1 - 6.2e-40 137.0 1.2 1.6e-39 135.6 0.8 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CAR30373.1 - 1.8e-22 79.9 0.0 5.8e-22 78.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 CAR30373.1 - 9.7e-07 28.3 0.0 3.1e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 CAR30373.1 - 1.6e-06 28.1 1.5 2.9e-06 27.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CAR30373.1 - 7.2e-06 25.7 0.0 1.9e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CAR30373.1 - 1.3e-05 25.3 0.0 0.00086 19.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CAR30373.1 - 4.2e-05 24.3 0.3 0.00029 21.6 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CAR30373.1 - 6.9e-05 22.9 0.3 0.0016 18.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 CAR30373.1 - 0.00047 20.3 0.0 0.16 12.1 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.1 CAR30373.1 - 0.00055 19.8 0.1 0.0026 17.6 0.0 2.3 3 0 0 3 3 1 1 AAA domain RuvB_N PF05496.7 CAR30373.1 - 0.0019 17.3 0.0 0.017 14.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CAR30373.1 - 0.0019 18.5 2.7 0.0085 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 CAR30373.1 - 0.0021 16.8 0.0 0.0049 15.5 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain SKI PF01202.17 CAR30373.1 - 0.013 15.3 0.3 0.048 13.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase MMR_HSR1 PF01926.18 CAR30373.1 - 0.041 13.8 0.4 6.1 6.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 CAR30373.1 - 0.043 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 CAR30373.1 - 0.045 12.4 4.5 0.17 10.5 0.1 2.6 3 0 0 3 3 3 0 TIP49 C-terminus DUF258 PF03193.11 CAR30373.1 - 0.046 12.9 0.3 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CAR30373.1 - 0.046 13.4 0.5 0.78 9.4 0.0 2.9 2 1 1 3 3 2 0 NTPase CBFD_NFYB_HMF PF00808.18 CAR30374.1 - 3.8e-26 90.9 0.0 6.3e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CAR30374.1 - 2.3e-06 27.6 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CAR30374.1 - 0.081 12.6 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Bromodomain associated Rft-1 PF04506.8 CAR30375.1 - 1.4e-162 541.9 35.0 1.6e-162 541.7 24.3 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 CAR30375.1 - 0.015 14.5 1.9 0.015 14.5 1.3 4.7 3 1 2 5 5 5 0 Polysaccharide biosynthesis protein Exo_endo_phos PF03372.18 CAR30376.1 - 6e-17 62.3 0.0 8.4e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CAR30376.1 - 2.4e-11 43.2 0.0 2e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 CAR30376.1 - 1.4e-09 37.7 2.5 2.8e-09 36.7 1.7 1.5 1 0 0 1 1 1 1 GRF zinc finger DIT1_PvcA PF05141.7 CAR30376.1 - 0.0042 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Imm40 PF15582.1 CAR30377.1 - 0.09 11.4 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 40 PAF-AH_p_II PF03403.8 CAR30377.1 - 0.095 10.9 0.0 0.1 10.8 0.0 1.0 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II BNR PF02012.15 CAR30378.1 - 0.00015 21.0 50.6 0.16 11.8 0.3 11.8 12 0 0 12 12 12 6 BNR/Asp-box repeat Mo-co_dimer PF03404.11 CAR30378.1 - 0.036 13.7 3.3 3.6 7.2 0.0 4.8 4 1 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain Caa3_CtaG PF09678.5 CAR30378.1 - 0.71 8.7 0.0 1.1 8.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Pkinase PF00069.20 CAR30379.1 - 2e-71 240.2 0.0 2.3e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30379.1 - 9.2e-29 100.2 0.0 1.4e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30379.1 - 0.00043 19.3 0.0 0.00077 18.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CAR30379.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CAR30379.1 - 0.051 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family AcetylCoA_hydro PF02550.10 CAR30380.1 - 2.2e-60 203.8 0.0 3.6e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 CAR30380.1 - 1.5e-40 138.3 0.0 2.4e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.7 CAR30380.1 - 0.0071 15.0 0.3 0.036 12.7 0.1 1.9 2 0 0 2 2 2 1 Citrate lyase, alpha subunit (CitF) Acid_PPase PF12689.2 CAR30381.1 - 1.9e-45 154.5 0.0 2.2e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HSP70 PF00012.15 CAR30382.1 - 3e-271 900.6 7.7 3.5e-271 900.4 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CAR30382.1 - 5.5e-18 64.6 0.0 8.9e-17 60.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CAR30382.1 - 0.0025 17.4 0.0 0.0063 16.1 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CAR30382.1 - 0.0027 16.8 1.0 0.012 14.7 0.0 2.4 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 CAR30382.1 - 0.027 13.7 0.0 6.1 6.0 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family UPF0121 PF03661.8 CAR30383.1 - 1e-08 34.6 5.8 2.7e-08 33.3 4.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) SHNi-TPR PF10516.4 CAR30384.1 - 1.2e-17 62.8 3.4 6.7e-16 57.2 0.1 4.1 4 0 0 4 4 4 1 SHNi-TPR TPR_12 PF13424.1 CAR30384.1 - 2.6e-06 27.2 4.8 0.0035 17.2 0.1 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 CAR30384.1 - 4.9e-05 22.8 2.8 0.33 10.6 0.0 3.3 2 1 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 CAR30384.1 - 0.0026 17.4 2.0 0.045 13.5 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CAR30384.1 - 0.0038 17.1 0.0 3.8 7.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR30384.1 - 0.009 15.8 6.3 0.028 14.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CAR30384.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CAR30384.1 - 0.41 10.5 3.4 76 3.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Septin PF00735.13 CAR30385.1 - 3.7e-110 367.3 1.0 4.3e-110 367.1 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CAR30385.1 - 0.00034 20.5 0.0 0.00093 19.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CAR30385.1 - 0.0028 17.6 0.2 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CAR30385.1 - 0.003 16.7 0.3 0.0097 15.1 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CAR30385.1 - 0.0078 16.5 2.6 0.29 11.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 CAR30385.1 - 0.0096 15.3 0.0 0.5 9.7 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Lipocalin PF00061.18 CAR30385.1 - 0.012 15.5 2.0 0.018 15.0 0.8 1.7 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family AAA_22 PF13401.1 CAR30385.1 - 0.059 13.5 0.1 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CAR30385.1 - 0.083 12.7 0.2 0.083 12.7 0.2 3.1 2 1 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 CAR30385.1 - 0.34 10.2 0.1 0.34 10.2 0.0 1.9 2 1 0 2 2 2 0 AAA-like domain DUF2937 PF11157.3 CAR30385.1 - 0.39 10.0 4.4 0.67 9.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF2852 PF11014.3 CAR30385.1 - 0.76 9.7 7.1 0.063 13.2 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF342 PF03961.8 CAR30385.1 - 1.8 6.8 12.8 2.9 6.1 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FAM150 PF15129.1 CAR30385.1 - 5.5 6.8 8.9 0.54 10.1 2.6 1.9 2 0 0 2 2 2 0 FAM150 family IncA PF04156.9 CAR30385.1 - 7.1 6.1 13.4 15 5.1 9.3 1.5 1 0 0 1 1 1 0 IncA protein GIT_SHD PF08518.6 CAR30386.1 - 3.7e-21 74.1 9.4 1.1e-12 47.0 0.3 3.7 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT CENP-F_leu_zip PF10473.4 CAR30386.1 - 0.003 17.4 13.4 0.003 17.4 9.3 4.0 4 1 1 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 vMSA PF00695.14 CAR30386.1 - 1.7 7.7 2.7 1 8.5 0.2 1.8 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Ribonucleas_3_3 PF14622.1 CAR30387.1 - 3e-20 72.4 0.0 5.3e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CAR30387.1 - 0.00083 19.7 0.0 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain DEAD PF00270.24 CAR30388.1 - 8.1e-41 139.3 0.0 1.8e-40 138.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30388.1 - 1e-26 92.6 0.2 6.1e-26 90.0 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR30388.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CAR30388.1 - 0.028 14.5 0.1 0.11 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATP-synt_G PF04718.10 CAR30389.1 - 4e-28 98.0 0.3 4.7e-28 97.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit MCM PF00493.18 CAR30390.1 - 9.9e-140 465.0 0.3 1.7e-139 464.2 0.2 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CAR30390.1 - 9.6e-23 80.9 3.6 9.6e-23 80.9 2.5 2.9 3 1 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 CAR30390.1 - 1.7e-06 27.8 0.0 1.1e-05 25.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CAR30390.1 - 4e-06 26.1 0.0 0.00019 20.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CAR30390.1 - 0.0022 17.6 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CAR30390.1 - 0.057 12.8 0.3 3.5 7.0 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain CAF1A PF12253.3 CAR30391.1 - 5.8e-21 74.3 12.2 5.8e-21 74.3 8.4 3.3 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 CAR30391.1 - 2e-16 60.0 84.8 2e-16 60.0 58.8 2.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ANTH PF07651.11 CAR30392.1 - 0.00052 18.8 0.4 0.001 17.8 0.3 1.4 1 0 0 1 1 1 1 ANTH domain DUF4515 PF14988.1 CAR30392.1 - 0.0017 18.0 0.8 0.0017 18.0 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) GAS PF13851.1 CAR30392.1 - 0.003 16.7 1.8 0.003 16.7 1.2 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding NTR2 PF15458.1 CAR30392.1 - 0.56 9.4 8.7 0.1 11.8 1.0 2.5 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Mss4 PF04421.8 CAR30393.1 - 9.9e-13 47.7 0.0 3.4e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Mss4 protein eIF-6 PF01912.13 CAR30394.1 - 4.5e-85 283.7 0.5 5.7e-85 283.4 0.4 1.1 1 0 0 1 1 1 1 eIF-6 family zf-C2H2 PF00096.21 CAR30395.1 - 2e-12 46.6 8.2 5.4e-06 26.4 0.8 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CAR30395.1 - 1.9e-08 34.1 8.4 0.00015 21.8 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CAR30395.1 - 2.8e-07 30.3 5.6 0.0042 17.3 0.6 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CAR30395.1 - 2.4e-05 24.0 3.0 0.016 15.0 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR30395.1 - 0.0063 16.6 2.7 0.14 12.3 0.0 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CAR30395.1 - 0.011 15.5 5.7 0.1 12.4 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_5 PF13719.1 CAR30395.1 - 0.021 14.3 0.1 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CAR30395.1 - 0.022 14.4 0.4 1 9.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 CAR30395.1 - 0.026 14.2 5.3 1.1 8.9 0.1 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 CAR30395.1 - 0.11 12.7 0.2 0.11 12.7 0.1 2.3 3 0 0 3 3 2 0 Zinc-finger of C2H2 type JCAD PF15351.1 CAR30395.1 - 0.32 8.5 5.6 0.35 8.4 3.9 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Mito_carr PF00153.22 CAR30396.1 - 1e-74 246.3 2.7 3e-25 87.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.6 CAR30397.1 - 0.00011 21.8 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Xan_ur_permease PF00860.15 CAR30398.1 - 5.7e-59 199.5 31.9 8.9e-59 198.9 22.1 1.2 1 0 0 1 1 1 1 Permease family Transcrip_reg PF01709.15 CAR30399.1 - 1.4e-74 250.1 0.1 1.7e-74 249.9 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator ATP-synt_F PF01990.12 CAR30400.1 - 1.4e-31 108.7 0.0 1.6e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 CAR30400.1 - 0.025 13.8 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 BRCT PF00533.21 CAR30401.1 - 3.9e-11 42.9 0.0 8.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CAR30401.1 - 2.1e-07 30.6 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain PT PF04886.7 CAR30401.1 - 0.0017 17.6 24.0 0.11 11.8 12.2 3.4 1 1 1 2 2 2 1 PT repeat DUF3006 PF11213.3 CAR30401.1 - 0.0039 16.9 0.1 0.0099 15.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 CAR30401.1 - 0.0088 16.1 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain CVNH PF08881.5 CAR30401.1 - 0.035 14.3 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 CVNH domain Aminotran_3 PF00202.16 CAR30402.1 - 2.5e-87 292.8 0.0 2.9e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pyridox_oxase_2 PF12766.2 CAR30403.1 - 3.1e-31 107.6 0.1 5.5e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase tRNA_bind PF01588.15 CAR30404.1 - 3.1e-15 55.7 0.0 4.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Ras PF00071.17 CAR30405.1 - 3.5e-50 169.5 0.0 4.4e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR30405.1 - 2.2e-18 66.8 0.0 4.1e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR30405.1 - 6.6e-08 31.9 0.1 7.9e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR30405.1 - 2.7e-07 30.2 0.1 5.8e-07 29.1 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR30405.1 - 0.0031 17.4 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CAR30405.1 - 0.063 12.4 0.1 0.11 11.6 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Gly_transf_sug PF04488.10 CAR30406.1 - 9.5e-14 51.6 0.0 2.2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CAR30406.1 - 0.028 12.9 0.1 0.3 9.5 0.0 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Isochorismatase PF00857.15 CAR30407.1 - 1.5e-25 90.1 0.0 2.7e-25 89.3 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family NUC153 PF08159.7 CAR30409.1 - 2.6e-13 49.2 5.7 5.3e-13 48.3 4.0 1.6 1 0 0 1 1 1 1 NUC153 domain SNARE PF05739.14 CAR30410.1 - 0.00097 18.7 4.4 0.00097 18.7 3.0 4.1 4 2 1 5 5 5 1 SNARE domain V-SNARE_C PF12352.3 CAR30410.1 - 0.34 11.0 9.4 0.82 9.7 0.1 3.6 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Ecl1 PF12855.2 CAR30411.1 - 6.8e-16 57.2 3.1 1.1e-15 56.6 2.1 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-FCS PF06467.9 CAR30411.1 - 0.29 10.7 2.4 0.58 9.8 1.7 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 CAR30412.1 - 6.7e-09 35.6 16.5 4.3e-06 26.7 2.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CAR30412.1 - 2.8e-07 30.4 15.8 0.00088 19.4 1.3 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR30412.1 - 3.2e-06 27.0 11.2 0.0087 16.3 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger TBPIP PF07106.8 CAR30414.1 - 7e-41 139.5 7.5 8.3e-41 139.3 5.2 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliS PF02561.9 CAR30414.1 - 0.038 13.8 2.5 0.14 11.9 0.3 2.5 1 1 1 2 2 2 0 Flagellar protein FliS Mnd1 PF03962.10 CAR30414.1 - 0.056 13.0 4.3 0.087 12.4 3.0 1.4 1 0 0 1 1 1 0 Mnd1 family Vps23_core PF09454.5 CAR30414.1 - 0.097 12.2 0.6 2 8.1 0.0 2.8 3 1 0 3 3 3 0 Vps23 core domain DUF1447 PF07288.6 CAR30414.1 - 0.12 12.2 0.7 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) CDC37_N PF03234.9 CAR30414.1 - 1.6 9.0 5.3 3.6 7.8 3.7 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Uricase PF01014.13 CAR30415.1 - 6.7e-72 240.0 0.3 2.6e-38 131.2 0.6 2.0 2 0 0 2 2 2 2 Uricase DUF1279 PF06916.8 CAR30416.1 - 1.9e-24 85.7 0.0 4e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L24e PF01246.15 CAR30418.1 - 2.8e-34 116.7 0.4 2.8e-34 116.7 0.3 2.4 2 1 1 3 3 3 1 Ribosomal protein L24e DUF775 PF05603.7 CAR30418.1 - 0.21 11.0 2.0 0.26 10.8 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PVL_ORF50 PF07768.6 CAR30418.1 - 0.35 10.8 12.2 0.46 10.4 8.4 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family U79_P34 PF03064.11 CAR30418.1 - 0.55 9.7 12.2 0.73 9.3 8.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.7 CAR30418.1 - 1.7 8.4 9.4 2 8.2 6.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L7Ae PF01248.21 CAR30419.1 - 6.6e-25 86.4 0.1 7.4e-25 86.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CHCH PF06747.8 CAR30420.1 - 1.9e-05 24.4 1.3 4.2e-05 23.3 0.9 1.6 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CAR30420.1 - 0.0031 17.5 1.0 0.0046 16.9 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CAR30420.1 - 0.083 12.6 1.9 0.12 12.2 1.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like tRNA-synt_2 PF00152.15 CAR30421.1 - 9e-81 271.2 0.3 9e-81 271.2 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR30421.1 - 6.1e-07 29.1 0.2 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CAR30421.1 - 0.099 11.8 0.7 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Lipase_GDSL_3 PF14606.1 CAR30421.1 - 0.42 10.3 3.8 1.3 8.7 0.8 2.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family RasGEF PF00617.14 CAR30422.1 - 3.6e-60 202.9 0.3 9.5e-60 201.5 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CAR30422.1 - 3.7e-18 65.5 0.0 1.9e-17 63.2 0.0 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 CAR30422.1 - 1e-10 40.9 0.1 1.6e-09 37.1 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CAR30422.1 - 1e-08 34.5 0.1 2.5e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CAR30422.1 - 1.7e-07 30.4 0.2 5.3e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 SH3 domain GRIP PF01465.15 CAR30423.1 - 2.8e-15 55.5 2.0 3.3e-15 55.3 0.2 2.1 2 0 0 2 2 2 1 GRIP domain Spc7 PF08317.6 CAR30423.1 - 0.00059 18.5 20.0 0.00059 18.5 13.8 7.1 2 2 6 8 8 8 4 Spc7 kinetochore protein Sec8_exocyst PF04048.9 CAR30423.1 - 0.0023 17.5 12.6 0.0023 17.5 8.8 7.5 3 2 3 7 7 7 2 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.7 CAR30423.1 - 0.0044 16.7 23.8 0.0044 16.7 16.5 8.9 2 2 7 9 9 9 5 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 CAR30423.1 - 2.6 5.6 152.7 0.011 13.5 24.1 4.1 1 1 2 4 4 4 0 Myosin tail CENP-F_leu_zip PF10473.4 CAR30423.1 - 5.1 6.9 168.6 0.047 13.5 17.2 9.0 3 2 5 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CAR30423.1 - 8.3 5.4 67.4 0.18 10.9 10.7 6.1 2 2 4 6 6 6 0 Reovirus sigma C capsid protein Methyltransf_11 PF08241.7 CAR30424.1 - 3.2e-17 62.8 0.0 5.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR30424.1 - 3e-13 50.0 0.0 5.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR30424.1 - 9.6e-11 41.4 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CAR30424.1 - 7.1e-10 38.8 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR30424.1 - 8.9e-10 39.1 0.0 1.5e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR30424.1 - 2.4e-09 36.6 0.0 4.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CAR30424.1 - 1.4e-08 34.9 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR30424.1 - 5e-06 26.5 0.0 1.7e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CAR30424.1 - 1.9e-05 24.0 0.0 3.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 CAR30424.1 - 0.04 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.6 CAR30424.1 - 0.067 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase SAP PF02037.22 CAR30424.1 - 0.085 12.3 0.1 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 SAP domain Polysacc_deac_1 PF01522.16 CAR30425.1 - 3.5e-23 81.5 0.0 5.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase UQ_con PF00179.21 CAR30426.1 - 3.3e-33 114.0 0.0 4.1e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CAR30426.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 UEV domain OTCace_N PF02729.16 CAR30427.1 - 1.3e-41 141.5 0.2 3.8e-41 140.0 0.1 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CAR30427.1 - 1.9e-41 141.5 0.1 3.6e-41 140.6 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain RNA_lig_T4_1 PF09511.5 CAR30428.1 - 2.3e-78 262.6 0.0 5e-78 261.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 CAR30428.1 - 1.3e-72 243.1 0.0 3.6e-72 241.6 0.0 1.8 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 CAR30428.1 - 2.5e-57 194.0 0.1 4.1e-57 193.3 0.1 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain Glutaminase PF04960.10 CAR30428.1 - 0.17 10.8 0.2 0.45 9.4 0.0 1.7 2 0 0 2 2 2 0 Glutaminase Exo70 PF03081.10 CAR30429.1 - 3.8e-89 299.0 3.7 3.8e-89 299.0 2.5 1.8 3 0 0 3 3 3 1 Exo70 exocyst complex subunit NAS PF03059.11 CAR30429.1 - 0.033 13.3 0.1 1.5 7.9 0.0 2.8 3 0 0 3 3 3 0 Nicotianamine synthase protein Arrestin_C PF02752.17 CAR30430.1 - 6.4e-17 61.9 0.1 7.7e-16 58.4 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CAR30430.1 - 1.1e-12 47.9 0.0 2e-08 34.1 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Vps51 PF08700.6 CAR30431.1 - 8.8e-11 41.5 2.7 1.1e-10 41.2 1.1 1.7 1 1 1 2 2 2 1 Vps51/Vps67 HBS1_N PF08938.5 CAR30431.1 - 0.0028 17.7 0.3 0.004 17.2 0.2 1.4 1 1 0 1 1 1 1 HBS1 N-terminus EF-hand_4 PF12763.2 CAR30432.1 - 0.00035 20.2 0.0 0.00082 19.0 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3808 PF10300.4 CAR30433.1 - 1e-162 541.9 2.0 1.3e-162 541.6 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 CAR30433.1 - 0.0015 19.1 2.3 0.38 11.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CAR30433.1 - 0.0046 16.7 2.7 0.62 9.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CAR30433.1 - 0.095 12.3 1.5 0.98 9.1 0.1 3.1 3 0 0 3 3 3 0 TPR repeat IBR PF01485.16 CAR30434.1 - 8.8e-15 54.3 42.5 9.3e-09 35.0 8.1 3.7 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 CAR30434.1 - 6.1e-06 25.8 15.0 6.1e-06 25.8 10.4 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CAR30434.1 - 0.0016 18.4 13.1 0.0016 18.4 9.1 5.7 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF1810 PF08837.6 CAR30434.1 - 0.045 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) Actin PF00022.14 CAR30435.1 - 2e-95 319.5 0.0 1e-94 317.1 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CAR30435.1 - 0.08 11.5 0.0 0.28 9.7 0.0 1.8 3 0 0 3 3 3 0 MreB/Mbl protein Mitofilin PF09731.4 CAR30436.1 - 2.1e-104 350.2 24.1 2.2e-92 310.5 15.9 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF2746 PF10874.3 CAR30436.1 - 0.079 13.1 0.5 29 4.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) tRNA-synt_His PF13393.1 CAR30436.1 - 0.55 9.2 12.1 0.26 10.2 3.0 2.8 1 1 0 2 2 2 0 Histidyl-tRNA synthetase Ric8 PF10165.4 CAR30437.1 - 0.0043 15.9 0.0 0.43 9.3 0.0 2.1 2 0 0 2 2 2 2 Guanine nucleotide exchange factor synembryn Ras PF00071.17 CAR30438.1 - 5.1e-54 182.0 0.1 6.1e-54 181.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR30438.1 - 5.6e-20 72.0 0.1 1.3e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CAR30438.1 - 4.9e-13 48.6 0.0 6.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR30438.1 - 3.2e-06 26.7 0.0 1.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CAR30438.1 - 8.6e-06 25.0 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CAR30438.1 - 9.3e-05 22.3 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CAR30438.1 - 0.016 13.9 0.0 0.33 9.5 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 CAR30438.1 - 0.061 12.5 0.1 0.13 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CAR30438.1 - 0.095 12.6 0.1 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain KH_1 PF00013.24 CAR30439.1 - 1.8e-73 242.0 29.7 8.6e-12 44.5 0.6 11.9 12 1 0 12 12 12 8 KH domain KH_3 PF13014.1 CAR30439.1 - 1.3e-42 142.7 29.5 6.7e-08 32.0 0.1 10.0 10 0 0 10 10 10 6 KH domain KH_2 PF07650.12 CAR30439.1 - 1.5e-10 40.4 20.5 0.0019 17.6 0.4 7.9 5 2 1 6 6 6 4 KH domain KH_4 PF13083.1 CAR30439.1 - 1.2e-07 31.2 12.3 0.077 12.6 0.0 6.9 8 0 0 8 8 8 3 KH domain BMC PF00936.14 CAR30439.1 - 1.3e-05 24.8 5.2 1.4 8.6 0.1 5.9 6 0 0 6 6 6 2 BMC domain HTH_19 PF12844.2 CAR30439.1 - 0.057 13.4 0.0 3.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain CAP PF00188.21 CAR30440.1 - 9.2e-20 71.3 6.6 1.3e-19 70.9 4.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Med3 PF11593.3 CAR30440.1 - 0.45 9.6 7.0 0.54 9.4 4.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAP PF00188.21 CAR30441.1 - 2.3e-21 76.5 3.5 2.3e-21 76.5 2.4 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family MFS_1 PF07690.11 CAR30442.1 - 4.1e-31 107.9 40.7 4.1e-31 107.9 28.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CAR30442.1 - 6.5e-09 34.5 1.6 1e-08 33.8 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_7 PF03441.9 CAR30444.1 - 5.3e-85 284.9 0.3 8.6e-85 284.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CAR30444.1 - 1.5e-29 102.8 1.5 3.2e-29 101.7 1.0 1.5 1 0 0 1 1 1 1 DNA photolyase DUF3485 PF11984.3 CAR30444.1 - 0.019 14.0 0.1 0.046 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Cytokin_check_N PF10407.4 CAR30445.1 - 1.1e-26 92.1 0.9 2.2e-26 91.2 0.6 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus SMC_N PF02463.14 CAR30446.1 - 4.4e-57 192.8 28.0 2.2e-56 190.5 19.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CAR30446.1 - 1.5e-28 99.1 0.0 5.8e-28 97.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CAR30446.1 - 2.9e-17 63.6 0.4 2.9e-17 63.6 0.3 6.6 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 CAR30446.1 - 2e-11 44.4 25.9 3.3e-06 27.2 5.3 4.1 3 1 0 3 3 3 2 AAA domain IncA PF04156.9 CAR30446.1 - 0.0012 18.4 8.0 0.0012 18.4 5.6 6.9 2 2 5 7 7 7 1 IncA protein CENP-F_leu_zip PF10473.4 CAR30446.1 - 0.0022 17.8 6.5 0.0022 17.8 4.5 7.1 3 2 2 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.1 CAR30446.1 - 0.0037 16.7 0.0 0.0093 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.4 CAR30446.1 - 0.0084 16.2 5.4 0.0084 16.2 3.8 9.6 7 4 1 9 9 9 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mem_trans PF03547.13 CAR30447.1 - 5.3e-58 196.1 10.6 2.7e-57 193.8 7.4 1.8 1 1 0 1 1 1 1 Membrane transport protein DnaJ PF00226.26 CAR30448.1 - 3.9e-21 74.5 1.9 1.2e-20 72.9 1.3 1.9 1 0 0 1 1 1 1 DnaJ domain Peptidase_M28 PF04389.12 CAR30449.1 - 1.4e-35 122.6 0.0 2.2e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CAR30449.1 - 1e-12 47.6 0.0 2.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CAR30449.1 - 4.2e-05 23.1 0.0 7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CAR30449.1 - 0.00053 18.8 0.0 0.0012 17.7 0.0 1.5 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Sld5 PF05916.6 CAR30451.1 - 7.1e-16 58.4 0.3 1.1e-15 57.8 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein DUF619 PF04768.8 CAR30452.1 - 3.3e-48 163.3 0.5 9.4e-48 161.8 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF619) DUF3354 PF11834.3 CAR30452.1 - 0.21 11.2 3.7 0.093 12.3 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) A_deaminase PF00962.17 CAR30453.1 - 1.3e-14 53.8 0.0 1.3e-07 30.8 0.0 3.5 3 1 0 3 3 3 3 Adenosine/AMP deaminase SHMT PF00464.14 CAR30454.1 - 3.9e-202 670.9 0.0 4.6e-202 670.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Ras PF00071.17 CAR30455.1 - 2.3e-40 137.6 0.4 1.6e-39 134.8 0.3 1.9 1 1 0 1 1 1 1 Ras family Arf PF00025.16 CAR30455.1 - 4.5e-17 61.8 0.2 9.7e-17 60.7 0.1 1.4 1 1 1 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CAR30455.1 - 1e-16 61.5 0.1 1.4e-16 61.0 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CAR30455.1 - 2.8e-07 30.4 0.1 5.2e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR30455.1 - 1.5e-05 24.4 0.1 0.0036 16.7 0.1 2.7 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CAR30455.1 - 2.8e-05 23.4 0.0 3.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CAR30455.1 - 0.00029 20.0 0.0 0.00035 19.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CAR30455.1 - 0.031 12.9 1.9 1.9 7.0 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit DAP3 PF10236.4 CAR30455.1 - 0.13 11.2 0.0 0.29 10.0 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF258 PF03193.11 CAR30455.1 - 0.13 11.3 0.0 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Rif1_N PF12231.3 CAR30456.1 - 2.1e-29 102.6 12.5 6.2e-29 101.1 8.7 1.8 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.20 CAR30457.1 - 1.4e-60 204.6 0.0 1.8e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30457.1 - 1.5e-32 112.6 0.0 2.1e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30457.1 - 2.1e-06 26.9 0.0 4.4e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CAR30457.1 - 0.024 13.4 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 CAR30457.1 - 0.046 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 CAR30457.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CAR30457.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family UBX PF00789.15 CAR30458.1 - 1.8e-16 59.9 0.0 4.4e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF4047 PF13256.1 CAR30458.1 - 0.18 11.7 2.3 0.37 10.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Snf7 PF03357.16 CAR30459.1 - 5.9e-12 45.3 15.8 8.9e-12 44.7 10.9 1.2 1 0 0 1 1 1 1 Snf7 End3 PF12761.2 CAR30459.1 - 0.3 10.7 9.5 3.3 7.3 0.0 2.6 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 DUF342 PF03961.8 CAR30459.1 - 3.1 6.1 12.9 0.071 11.5 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DNA_topoisoIV PF00521.15 CAR30459.1 - 6.1 5.5 10.3 9.9 4.8 7.1 1.4 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A E3_UbLigase_R4 PF13764.1 CAR30460.1 - 0.021 12.7 0.2 0.026 12.4 0.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 rRNA_proc-arch PF13234.1 CAR30461.1 - 3.9e-85 285.2 2.4 3.9e-85 285.2 1.6 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 CAR30461.1 - 8.2e-63 210.8 2.1 1.6e-62 209.9 0.2 2.4 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CAR30461.1 - 9.9e-22 77.2 0.0 1.1e-20 73.8 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30461.1 - 2.9e-06 27.0 0.0 7.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3885 PF13021.1 CAR30461.1 - 0.093 12.4 2.9 11 5.8 0.0 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3885) Vps26 PF03643.10 CAR30463.1 - 5.2e-111 369.8 0.0 6e-111 369.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CAR30463.1 - 2.2e-05 24.2 0.7 0.002 17.9 0.2 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CAR30463.1 - 0.051 13.6 0.2 0.21 11.6 0.2 2.3 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain COX3 PF00510.13 CAR30463.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit III Tim54 PF11711.3 CAR30464.1 - 2.8e-139 463.9 1.7 3.4e-139 463.6 1.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF4140 PF13600.1 CAR30464.1 - 0.24 11.8 3.3 0.49 10.8 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Myb_DNA-binding PF00249.26 CAR30465.1 - 4.4e-23 81.0 0.1 3.5e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CAR30465.1 - 6.6e-18 64.5 1.1 7.1e-14 51.6 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Lysine_decarbox PF03641.9 CAR30466.1 - 2.8e-45 153.4 0.1 3.9e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase zf-BED PF02892.10 CAR30466.1 - 0.11 12.2 0.5 0.52 10.1 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 CAR30467.1 - 6.9e-29 98.6 46.0 1.8e-09 37.4 0.2 8.2 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.21 CAR30467.1 - 1.5e-23 81.6 62.3 3.1e-06 27.1 1.0 9.6 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR30467.1 - 1.3e-16 59.6 52.1 0.00032 20.8 2.3 9.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CAR30467.1 - 3.7e-13 49.2 19.7 0.00049 20.1 0.1 5.9 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 CAR30467.1 - 1.5e-07 30.9 13.9 0.0044 16.6 0.6 4.8 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 CAR30467.1 - 6.4e-07 29.0 35.3 0.00028 20.6 0.5 6.3 6 1 1 7 7 7 4 C2H2-type zinc finger Nif11 PF07862.6 CAR30467.1 - 0.064 13.2 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function DUF2225 PF09986.4 CAR30467.1 - 0.57 9.6 9.9 1.3 8.3 1.4 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-met PF12874.2 CAR30467.1 - 0.82 9.9 27.2 0.13 12.5 0.5 5.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Phage_Orf51 PF06194.6 CAR30467.1 - 6.8 6.8 7.9 7.2 6.7 1.8 3.6 5 0 0 5 5 5 0 Phage Conserved Open Reading Frame 51 Methyltransf_16 PF10294.4 CAR30468.1 - 4.7e-23 81.5 0.0 7.4e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CAR30468.1 - 7e-08 32.3 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR30468.1 - 0.00068 19.2 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR30468.1 - 0.0021 18.5 0.0 0.0066 17.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR30468.1 - 0.0031 17.9 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CAR30468.1 - 0.025 14.6 0.0 0.056 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CAR30468.1 - 0.14 11.5 0.0 0.43 9.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 CAR30469.1 - 2.9e-34 118.3 0.0 2.1e-33 115.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30469.1 - 4.5e-20 71.8 0.0 2.2e-19 69.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M41 PF01434.13 CAR30469.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 HbrB PF08539.6 CAR30470.1 - 6.5e-35 120.3 1.1 9.8e-35 119.7 0.8 1.3 1 0 0 1 1 1 1 HbrB-like CLN3 PF02487.12 CAR30471.1 - 2e-131 438.5 18.8 4.1e-130 434.1 13.1 1.9 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 CAR30471.1 - 0.0008 18.2 3.9 0.0008 18.2 2.7 2.9 1 1 0 2 2 2 1 Major Facilitator Superfamily EmrE PF13536.1 CAR30471.1 - 0.043 14.0 1.1 0.043 14.0 0.8 2.8 1 1 1 2 2 2 0 Multidrug resistance efflux transporter Aminotran_1_2 PF00155.16 CAR30472.1 - 4.9e-80 269.1 0.0 5.9e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CAR30472.1 - 4.1e-05 22.7 0.0 6.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CAR30472.1 - 0.00051 18.9 0.0 0.0018 17.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CAR30472.1 - 0.0021 16.4 0.0 0.0044 15.3 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CAR30472.1 - 0.021 13.9 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF1674 PF07896.7 CAR30473.1 - 1.4e-15 57.2 3.0 2.8e-15 56.2 2.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Nup54 PF13874.1 CAR30474.1 - 2 8.0 14.8 0.26 10.9 6.3 2.2 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 CAR30474.1 - 8 6.0 25.6 1.4e+02 1.9 17.7 2.5 1 1 0 1 1 1 0 IncA protein Ribosomal_L37 PF08561.5 CAR30475.1 - 4.6e-29 99.8 0.5 5.7e-29 99.5 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Phosphodiest PF01663.17 CAR30476.1 - 2.3e-16 60.0 0.2 1e-10 41.4 0.0 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CAR30476.1 - 0.00061 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Fe-S_biosyn PF01521.15 CAR30476.1 - 0.003 17.4 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Sulfatase PF00884.18 CAR30476.1 - 0.034 13.3 0.0 0.084 12.0 0.0 1.7 1 1 0 1 1 1 0 Sulfatase DUF1700 PF08006.6 CAR30476.1 - 2.1 7.5 8.7 0.45 9.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) zf-C2H2_2 PF12756.2 CAR30477.1 - 7e-35 119.1 0.7 1.3e-31 108.6 0.2 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CAR30477.1 - 0.0064 16.6 0.5 3.1 8.0 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CAR30477.1 - 0.093 13.1 8.1 1.6 9.2 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CAR30477.1 - 0.14 12.5 0.7 18 5.9 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger AKAP95 PF04988.7 CAR30477.1 - 0.15 11.8 2.7 5.3 6.7 0.1 2.7 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) adh_short PF00106.20 CAR30478.1 - 8.5e-20 71.3 0.0 1.5e-19 70.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR30478.1 - 5.8e-13 48.9 0.0 8.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CAR30478.1 - 0.1 11.9 0.0 0.29 10.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 CAR30478.1 - 0.15 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_L17 PF01196.14 CAR30480.1 - 1e-27 96.4 0.1 2.8e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L17 PALP PF00291.20 CAR30481.1 - 3.5e-58 197.2 0.0 3.9e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.15 CAR30482.1 - 2.9e-25 88.4 1.3 1.9e-21 76.0 0.2 3.4 2 1 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR30482.1 - 1.8e-07 30.7 0.2 1.1e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CAR30482.1 - 0.029 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CBFD_NFYB_HMF PF00808.18 CAR30483.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CAR30483.1 - 0.052 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Trypan_PARP PF05887.6 CAR30483.1 - 0.75 9.6 12.8 1.3 8.8 8.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Paf1 PF03985.8 CAR30485.1 - 1.1e-140 469.3 14.2 1.2e-140 469.1 9.9 1.0 1 0 0 1 1 1 1 Paf1 DUF2762 PF10960.3 CAR30485.1 - 0.22 11.2 2.5 0.71 9.6 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) Esterase PF00756.15 CAR30486.1 - 1.9e-56 191.2 0.1 2.2e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CAR30486.1 - 0.00013 21.7 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CAR30486.1 - 0.025 14.4 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 CAR30486.1 - 0.038 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 CAR30486.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 CAR30486.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RCC1_2 PF13540.1 CAR30487.1 - 3e-14 52.1 17.3 1.1e-08 34.4 0.2 4.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CAR30487.1 - 1.8e-11 44.0 1.8 0.084 13.1 0.0 7.5 7 2 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 CAR30487.1 - 0.0022 17.6 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like CBM_X PF06204.6 CAR30487.1 - 0.038 13.4 0.2 5.2 6.6 0.0 3.3 3 0 0 3 3 3 0 Putative carbohydrate binding domain F-box PF00646.28 CAR30487.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain Peptidase_M20 PF01546.23 CAR30488.1 - 2e-19 69.8 0.0 3.5e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CAR30488.1 - 5e-13 48.7 0.0 8.9e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.27 CAR30488.1 - 5.8e-12 45.0 0.8 0.0016 18.2 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat SIMPL PF04402.9 CAR30488.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) WD40 PF00400.27 CAR30489.1 - 4e-17 61.3 0.0 4e-05 23.3 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CAR30489.1 - 0.0033 16.9 0.0 0.14 11.6 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3303 PF11746.3 CAR30489.1 - 0.022 15.1 0.2 0.078 13.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) DUF572 PF04502.8 CAR30489.1 - 0.69 9.0 6.4 0.98 8.5 4.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MRP-L27 PF09809.4 CAR30490.1 - 5.4e-31 106.5 1.1 8.6e-31 105.8 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.15 CAR30491.1 - 3.9e-59 200.3 15.4 5.2e-59 199.9 10.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CAR30491.1 - 1.3e-09 37.3 2.0 1.7e-09 36.9 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p Methyltransf_PK PF05891.7 CAR30493.1 - 9.6e-93 309.4 0.0 1.1e-92 309.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 CAR30493.1 - 6.3e-08 32.5 0.0 8.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR30493.1 - 6e-05 23.5 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CAR30493.1 - 0.064 13.7 0.0 0.24 11.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CAR30493.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain RhoGAP PF00620.22 CAR30494.1 - 7.1e-37 126.3 0.0 2.8e-36 124.3 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CAR30494.1 - 2.6e-14 53.1 2.3 6.3e-14 51.9 0.2 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Cullin PF00888.17 CAR30495.1 - 1e-11 44.1 3.3 2.9e-11 42.6 2.3 2.0 1 1 0 1 1 1 1 Cullin family PqqD PF05402.7 CAR30495.1 - 0.046 13.7 0.1 8.3 6.5 0.1 3.7 5 0 0 5 5 5 0 Coenzyme PQQ synthesis protein D (PqqD) PEPcase PF00311.12 CAR30495.1 - 0.092 10.5 0.7 0.13 10.1 0.1 1.5 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase MarR_2 PF12802.2 CAR30495.1 - 0.12 12.0 0.1 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 MarR family Cullin PF00888.17 CAR30496.1 - 1.2e-07 30.7 3.9 3e-07 29.3 0.0 2.4 2 1 0 2 2 2 2 Cullin family COMPASS-Shg1 PF05205.7 CAR30497.1 - 1.7e-23 82.9 0.5 2.1e-23 82.6 0.3 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DeoRC PF00455.17 CAR30497.1 - 0.095 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 DeoR C terminal sensor domain UPF0086 PF01868.11 CAR30498.1 - 1.2e-12 47.2 0.0 3.1e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function UPF0086 BPL_LplA_LipB PF03099.14 CAR30499.1 - 3.6e-21 75.4 0.0 6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PriCT_1 PF08708.6 CAR30499.1 - 0.053 13.3 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) zf-RING_UBOX PF13445.1 CAR30500.1 - 0.031 13.9 0.4 0.14 11.8 0.3 2.2 1 0 0 1 1 1 0 RING-type zinc-finger WD40 PF00400.27 CAR30500.1 - 0.16 11.9 4.6 9.6 6.2 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat PI-PLC-X PF00388.14 CAR30501.1 - 9.5e-13 47.7 0.0 2.6e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain WHIM1 PF15612.1 CAR30502.1 - 0.0032 17.3 0.1 0.0077 16.1 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Pkinase PF00069.20 CAR30503.1 - 8.4e-73 244.7 0.0 1.2e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30503.1 - 9.9e-40 136.2 0.0 1.8e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30503.1 - 3e-06 26.4 0.0 1.5e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like ABC1 PF03109.11 CAR30503.1 - 0.031 14.2 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.9 CAR30503.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glycogen_syn PF05693.8 CAR30504.1 - 0 1074.7 0.0 0 1074.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CAR30504.1 - 1.2e-08 34.6 0.0 7e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CAR30504.1 - 7.4e-06 26.1 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 CAR30504.1 - 1.4e-05 24.7 0.1 3.2e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain DUF1801 PF08818.6 CAR30505.1 - 0.095 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DU1801) SH3BGR PF04908.10 CAR30507.1 - 0.0099 15.8 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein NpwBP PF12622.2 CAR30507.1 - 0.018 15.4 3.3 0.084 13.3 0.0 3.8 3 0 0 3 3 3 0 mRNA biogenesis factor NAD_binding_6 PF08030.7 CAR30509.1 - 3.9e-17 62.5 0.0 5.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CAR30509.1 - 4.9e-17 62.1 12.1 4.9e-17 62.1 8.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CAR30509.1 - 2.2e-09 37.1 0.0 4.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 CAR30509.1 - 0.16 12.5 0.0 3.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Fungal_trans PF04082.13 CAR30510.1 - 3.3e-10 39.2 10.2 6.8e-10 38.2 5.4 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CAR30510.1 - 1.8e-08 34.1 9.2 4.1e-08 32.9 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OCD_Mu_crystall PF02423.10 CAR30511.1 - 2e-14 53.1 0.0 2.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Angiomotin_C PF12240.3 CAR30512.1 - 8.5e-06 25.4 4.6 7.1e-05 22.3 0.3 2.4 1 1 1 2 2 2 1 Angiomotin C terminal GAS PF13851.1 CAR30512.1 - 0.0003 20.0 4.9 0.0005 19.3 3.4 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 CAR30512.1 - 0.00046 20.0 1.2 0.00046 20.0 0.9 2.7 2 0 0 2 2 2 1 bZIP transcription factor Leu_zip PF15294.1 CAR30512.1 - 0.00049 19.3 8.3 0.0021 17.2 5.7 1.8 1 1 0 1 1 1 1 Leucine zipper DUF869 PF05911.6 CAR30512.1 - 0.0046 15.2 6.4 0.0057 14.9 4.5 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 CAR30512.1 - 0.0056 16.5 8.7 0.01 15.6 6.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kinetocho_Slk19 PF12709.2 CAR30512.1 - 0.0056 16.7 6.4 0.44 10.6 1.2 2.3 2 0 0 2 2 2 2 Central kinetochore-associated APG6 PF04111.7 CAR30512.1 - 0.0063 15.6 6.2 0.0094 15.0 4.3 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 BLOC1_2 PF10046.4 CAR30512.1 - 0.01 15.9 7.4 0.14 12.3 1.7 2.4 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.2 CAR30512.1 - 0.011 15.0 8.2 0.025 13.8 5.6 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF904 PF06005.7 CAR30512.1 - 0.016 15.4 11.8 0.35 11.1 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Filament PF00038.16 CAR30512.1 - 0.018 14.5 6.7 0.051 13.0 4.6 1.7 1 1 0 1 1 1 0 Intermediate filament protein IncA PF04156.9 CAR30512.1 - 0.021 14.4 15.8 1.4 8.5 10.9 2.2 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CAR30512.1 - 0.041 13.6 10.4 0.096 12.5 1.7 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 CAR30512.1 - 0.053 13.3 2.2 0.053 13.3 1.5 3.2 3 1 1 4 4 3 0 Basic region leucine zipper vATP-synt_E PF01991.13 CAR30512.1 - 0.06 12.6 7.0 0.059 12.6 0.7 2.2 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Phage_GP20 PF06810.6 CAR30512.1 - 0.063 12.7 6.5 1.8 8.0 0.4 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF972 PF06156.8 CAR30512.1 - 0.082 13.2 9.2 0.14 12.5 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CASP_C PF08172.7 CAR30512.1 - 0.16 10.9 11.0 0.049 12.6 1.6 2.3 1 1 1 2 2 2 0 CASP C terminal ACCA PF03255.9 CAR30512.1 - 0.17 11.3 3.3 0.13 11.7 0.9 1.7 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Lzipper-MIP1 PF14389.1 CAR30512.1 - 0.19 11.8 7.3 0.43 10.7 2.7 2.9 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Mnd1 PF03962.10 CAR30512.1 - 0.27 10.8 3.5 0.47 10.1 2.4 1.4 1 0 0 1 1 1 0 Mnd1 family PspA_IM30 PF04012.7 CAR30512.1 - 0.28 10.5 6.4 2.5 7.3 1.9 2.2 1 1 1 2 2 2 0 PspA/IM30 family Myosin_tail_1 PF01576.14 CAR30512.1 - 0.33 8.6 8.6 0.44 8.2 6.0 1.1 1 0 0 1 1 1 0 Myosin tail DUF641 PF04859.7 CAR30512.1 - 0.41 10.4 5.2 0.47 10.2 0.8 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Striatin PF08232.7 CAR30512.1 - 0.49 10.7 8.9 1.3e+02 2.8 6.2 2.4 1 1 0 1 1 1 0 Striatin family Tropomyosin PF00261.15 CAR30512.1 - 0.49 9.4 11.3 0.78 8.7 0.6 2.1 1 1 1 2 2 2 0 Tropomyosin PEP-utilisers_N PF05524.8 CAR30512.1 - 0.55 10.0 3.2 0.62 9.8 1.3 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal ADIP PF11559.3 CAR30512.1 - 0.59 10.0 8.7 8.3 6.2 1.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NYD-SP28 PF14772.1 CAR30512.1 - 0.6 10.2 5.3 0.34 11.0 1.5 1.9 2 0 0 2 2 2 0 Sperm tail Cortex-I_coil PF09304.5 CAR30512.1 - 0.75 9.8 9.4 1 9.4 1.7 2.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil TPR_MLP1_2 PF07926.7 CAR30512.1 - 1.2 8.8 12.0 7.7 6.2 8.3 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF837 PF05769.6 CAR30512.1 - 1.5 8.3 7.6 22 4.5 4.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF837) Cep57_MT_bd PF06657.8 CAR30512.1 - 1.6 8.6 6.5 1.6 8.7 1.1 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TSC22 PF01166.13 CAR30512.1 - 2.4 8.2 7.9 13 5.8 0.7 2.7 2 1 0 2 2 2 0 TSC-22/dip/bun family Med9 PF07544.8 CAR30512.1 - 2.5 7.8 5.7 18 5.1 2.4 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin_1 PF12718.2 CAR30512.1 - 2.6 7.8 12.3 14 5.4 7.3 2.1 1 1 1 2 2 2 0 Tropomyosin like TBPIP PF07106.8 CAR30512.1 - 2.7 7.5 8.9 11 5.4 0.5 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 CAR30512.1 - 2.7 5.7 6.4 5.7 4.6 4.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec2p PF06428.6 CAR30512.1 - 2.8 7.8 9.5 1.2 9.0 0.2 2.9 2 2 1 3 3 3 0 GDP/GTP exchange factor Sec2p Cep57_CLD_2 PF14197.1 CAR30512.1 - 3.6 7.5 10.5 8.5 6.3 1.5 3.3 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.15 CAR30512.1 - 4.7 7.0 11.4 2.4 7.9 3.0 2.5 1 1 1 2 2 2 0 Prefoldin subunit Med21 PF11221.3 CAR30512.1 - 8.4 6.3 11.6 0.14 12.1 1.2 2.5 2 1 0 2 2 2 0 Subunit 21 of Mediator complex TEX13 PF15186.1 CAR30512.1 - 9.6 5.7 8.2 20 4.7 0.5 2.3 1 1 0 2 2 2 0 Testis-expressed sequence 13 protein family ABC1 PF03109.11 CAR30513.1 - 3e-33 114.3 0.0 7.9e-33 112.9 0.0 1.8 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CAR30513.1 - 2.5e-05 23.7 0.0 0.00029 20.2 0.0 2.6 3 0 0 3 3 3 1 RIO1 family FimH_man-bind PF09160.5 CAR30513.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 FimH, mannose binding Mpv17_PMP22 PF04117.7 CAR30514.1 - 8.6e-27 92.5 3.4 1.9e-26 91.4 2.3 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.13 CAR30516.1 - 9.9e-07 28.5 10.7 9.9e-07 28.5 7.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_N PF13396.1 CAR30517.1 - 0.021 14.5 1.5 0.038 13.6 1.0 1.4 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal TP_methylase PF00590.15 CAR30518.1 - 6.4e-26 91.3 0.0 9.8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 CAR30518.1 - 0.0098 15.6 0.1 0.044 13.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4434) Clat_adaptor_s PF01217.15 CAR30519.1 - 2.9e-53 179.4 3.4 3.3e-53 179.2 2.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 CAR30521.1 - 2.5e-60 203.8 0.0 3.8e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30521.1 - 1.1e-24 86.8 0.0 2.4e-24 85.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30521.1 - 6.4e-05 22.0 0.0 0.057 12.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CAR30521.1 - 0.00082 18.4 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CAR30521.1 - 0.11 12.2 0.2 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC_tran PF00005.22 CAR30523.1 - 9.2e-46 155.5 0.0 2.5e-23 82.8 0.0 4.3 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CAR30523.1 - 5.8e-18 65.8 0.2 0.0015 18.5 0.0 4.5 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 CAR30523.1 - 7.2e-16 58.0 0.0 2.5e-06 26.9 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR30523.1 - 7.5e-10 39.4 1.0 0.0022 18.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CAR30523.1 - 1.9e-09 36.8 0.0 0.002 17.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CAR30523.1 - 1e-08 35.3 0.0 0.00045 20.3 0.0 3.9 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 CAR30523.1 - 1.6e-08 33.8 0.0 0.00021 20.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CAR30523.1 - 4.3e-08 34.0 0.0 0.0048 17.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CAR30523.1 - 4.4e-07 29.9 0.1 0.0083 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CAR30523.1 - 7.2e-07 29.1 0.0 5.8e-05 22.9 0.0 3.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CAR30523.1 - 7.9e-07 29.0 0.0 0.0058 16.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase CLASP_N PF12348.3 CAR30523.1 - 1.1e-06 28.1 3.3 0.00035 20.0 0.3 2.9 2 1 1 3 3 3 2 CLASP N terminal SbcCD_C PF13558.1 CAR30523.1 - 1.8e-06 27.7 0.1 0.009 15.9 0.0 3.5 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CAR30523.1 - 1.9e-06 27.5 0.1 0.28 10.5 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain ArgK PF03308.11 CAR30523.1 - 1.9e-06 26.8 0.1 0.057 12.1 0.0 2.5 2 0 0 2 2 2 2 ArgK protein Miro PF08477.8 CAR30523.1 - 3e-06 27.7 0.0 0.02 15.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 CAR30523.1 - 3.2e-06 27.0 0.0 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CAR30523.1 - 3.3e-06 27.3 0.4 0.53 10.4 0.0 4.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CAR30523.1 - 1e-05 25.6 0.0 0.11 12.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 CAR30523.1 - 5.5e-05 23.4 0.0 0.15 12.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 CAR30523.1 - 7.2e-05 22.5 0.0 0.37 10.4 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CAR30523.1 - 0.00011 22.2 0.2 0.23 11.4 0.0 3.8 4 0 0 4 4 4 1 AAA ATPase domain MutS_V PF00488.16 CAR30523.1 - 0.00016 21.1 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 1 MutS domain V Arch_ATPase PF01637.13 CAR30523.1 - 0.00022 21.0 0.2 0.81 9.3 0.0 3.5 4 0 0 4 4 3 1 Archaeal ATPase ParcG PF10274.4 CAR30523.1 - 0.00028 20.8 1.2 0.23 11.3 0.0 2.8 2 1 1 3 3 3 1 Parkin co-regulated protein DUF87 PF01935.12 CAR30523.1 - 0.00031 20.6 1.0 0.37 10.5 0.0 4.1 5 0 0 5 5 3 1 Domain of unknown function DUF87 NACHT PF05729.7 CAR30523.1 - 0.00058 19.5 0.0 0.49 10.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain PduV-EutP PF10662.4 CAR30523.1 - 0.00058 19.3 0.0 0.29 10.6 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 CAR30523.1 - 0.00076 19.3 0.0 2.6 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMS19_C PF12460.3 CAR30523.1 - 0.0011 17.7 0.4 0.39 9.3 0.0 3.1 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal AAA_30 PF13604.1 CAR30523.1 - 0.0019 17.8 0.1 3.9 7.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain HEAT_2 PF13646.1 CAR30523.1 - 0.002 18.3 7.5 0.2 11.9 0.0 4.0 1 1 2 3 3 3 1 HEAT repeats AAA_13 PF13166.1 CAR30523.1 - 0.0041 15.6 6.3 2.6 6.4 0.0 4.1 3 1 0 4 4 4 2 AAA domain cobW PF02492.14 CAR30523.1 - 0.0079 15.6 1.8 1.9 7.8 0.0 3.2 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain Cnd1 PF12717.2 CAR30523.1 - 0.011 15.6 0.1 0.13 12.1 0.0 2.7 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 T2SE PF00437.15 CAR30523.1 - 0.015 14.1 0.0 0.54 9.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 CAR30523.1 - 0.016 14.3 0.0 3 6.8 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 CAR30523.1 - 0.019 14.0 0.3 1 8.4 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI HEAT PF02985.17 CAR30523.1 - 0.021 14.8 2.9 9.7 6.5 0.0 4.1 5 0 0 5 5 2 0 HEAT repeat FtsK_SpoIIIE PF01580.13 CAR30523.1 - 0.041 13.3 0.4 2 7.8 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 CAR30523.1 - 0.048 13.0 0.0 11 5.3 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Septin PF00735.13 CAR30523.1 - 0.052 12.5 0.3 1.3 7.9 0.0 2.6 3 0 0 3 3 2 0 Septin AAA_19 PF13245.1 CAR30523.1 - 0.057 13.1 0.1 5.8 6.7 0.0 3.0 3 0 0 3 3 2 0 Part of AAA domain ATP_bind_1 PF03029.12 CAR30523.1 - 0.065 12.7 0.2 8.4 5.8 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UME PF08064.8 CAR30523.1 - 0.12 12.3 0.5 1.3 9.0 0.1 2.6 1 1 0 2 2 2 0 UME (NUC010) domain HEAT_EZ PF13513.1 CAR30523.1 - 1.2 9.6 9.1 6.4 7.3 0.1 4.5 5 0 0 5 5 3 0 HEAT-like repeat DUF843 PF05814.6 CAR30523.1 - 5 6.9 6.4 43 3.9 0.0 3.3 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) PLA2_B PF01735.13 CAR30524.1 - 5.5e-93 311.7 3.9 1.2e-77 261.2 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.17 CAR30524.1 - 5.7e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase EF-hand_7 PF13499.1 CAR30525.1 - 0.0018 18.3 3.0 0.0018 18.3 2.1 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CAR30525.1 - 0.007 15.6 2.7 0.1 11.9 0.2 2.6 2 0 0 2 2 2 1 EF hand HD_4 PF13328.1 CAR30525.1 - 0.028 14.1 0.8 0.17 11.5 0.5 2.1 1 1 0 1 1 1 0 HD domain Flavodoxin_1 PF00258.20 CAR30525.1 - 0.058 13.3 0.4 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin EF-hand_6 PF13405.1 CAR30525.1 - 0.075 12.9 5.8 4.3 7.4 0.1 3.1 4 0 0 4 4 4 0 EF-hand domain UPF0052 PF01933.13 CAR30526.1 - 2e-60 204.7 0.0 5.2e-60 203.3 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 HAD PF12710.2 CAR30527.1 - 2e-15 57.4 0.0 3.1e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CAR30527.1 - 5.2e-07 30.0 0.0 8.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CAR30527.1 - 2.9e-06 26.6 0.0 4.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 CAR30527.1 - 6.5e-06 25.6 0.0 4.7e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 CAR30527.1 - 0.00022 21.7 0.1 0.0052 17.2 0.0 2.5 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Iso_dh PF00180.15 CAR30528.1 - 1.3e-72 244.6 0.0 1.5e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase UEV PF05743.8 CAR30529.1 - 2.6e-23 81.9 0.0 4.7e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CAR30529.1 - 1.8e-19 69.1 0.0 4e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain SSFA2_C PF14723.1 CAR30529.1 - 0.0069 16.1 3.0 0.013 15.2 2.1 1.4 1 0 0 1 1 1 1 Sperm-specific antigen 2 C-terminus DKCLD PF08068.7 CAR30530.1 - 1.4e-29 101.7 0.3 5.2e-29 99.9 0.2 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CAR30530.1 - 9.9e-21 74.4 8.2 1.7e-19 70.4 0.0 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CAR30530.1 - 1.3e-20 72.9 1.2 3.1e-20 71.6 0.7 1.8 2 0 0 2 2 2 1 PUA domain GAGA_bind PF06217.7 CAR30530.1 - 0.26 11.2 15.9 0.37 10.7 11.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 CAR30530.1 - 7.7 5.6 23.8 13 4.8 16.5 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CTDII PF01556.13 CAR30531.1 - 2.6e-24 84.8 0.2 8.2e-21 73.7 0.0 2.6 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 CAR30531.1 - 1.9e-23 81.9 0.6 3.7e-23 81.0 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 CAR30532.1 - 9.6e-48 158.4 14.8 1.2e-11 43.9 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CAR30532.1 - 2.4e-10 39.1 10.1 0.0042 15.2 0.1 4.8 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CAR30532.1 - 1e-05 24.5 0.7 0.051 12.3 0.1 3.4 1 1 1 2 2 2 2 Nup133 N terminal like DUF3312 PF11768.3 CAR30532.1 - 7.6e-05 21.1 0.0 0.00051 18.4 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) RFX_DNA_binding PF02257.10 CAR30533.1 - 1.9e-32 111.2 0.1 4.9e-32 109.9 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 CAR30533.1 - 0.00068 19.8 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 Poxvirus D5 protein-like Collagen PF01391.13 CAR30533.1 - 3.2 7.3 19.7 5.7 6.5 13.6 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_L30 PF00327.15 CAR30534.1 - 1e-14 53.8 0.5 2.4e-14 52.6 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e CarD_CdnL_TRCF PF02559.11 CAR30534.1 - 2.2 8.3 5.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 CarD-like/TRCF domain Iso_dh PF00180.15 CAR30535.1 - 1.5e-132 441.7 0.0 1.8e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_ligase_aden PF01653.13 CAR30535.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Aminotran_5 PF00266.14 CAR30536.1 - 4.9e-98 328.2 0.0 6.9e-98 327.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CAR30536.1 - 2.2e-10 40.1 0.1 3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CAR30536.1 - 1.2e-09 37.7 1.0 6.8e-09 35.2 0.1 2.3 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CAR30536.1 - 0.0039 15.6 0.1 0.0064 14.9 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Transketolase_C PF02780.15 CAR30536.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain Mito_carr PF00153.22 CAR30537.1 - 1.1e-51 172.4 5.7 1.4e-18 66.3 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CAR30537.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.0 4 0 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family DUF2036 PF09724.4 CAR30538.1 - 6.1e-87 291.7 0.0 7e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF3507 PF12015.3 CAR30539.1 - 5.4e-56 188.9 0.0 1e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF1325 PF07039.6 CAR30540.1 - 1.6e-35 121.5 0.0 2.7e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 CAR30540.1 - 0.005 16.6 0.0 0.054 13.2 0.0 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4537) DASH_Dad2 PF08654.5 CAR30540.1 - 0.056 13.4 1.8 0.079 12.9 0.8 1.6 1 1 0 1 1 1 0 DASH complex subunit Dad2 Agenet PF05641.7 CAR30540.1 - 0.09 12.9 0.0 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Agenet domain PilZ PF07238.9 CAR30540.1 - 0.12 12.4 0.0 0.42 10.6 0.0 2.0 1 1 0 1 1 1 0 PilZ domain Retrotrans_gag PF03732.12 CAR30540.1 - 0.13 12.3 0.6 0.2 11.7 0.4 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein Pol_alpha_B_N PF08418.5 CAR30540.1 - 0.23 10.9 3.6 0.23 10.9 1.4 1.7 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Ribosomal_L27 PF01016.14 CAR30541.1 - 4e-30 103.4 0.1 7.3e-30 102.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein CtsR PF05848.6 CAR30541.1 - 0.036 14.0 0.4 0.083 12.8 0.3 1.6 1 0 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) L_lactis_RepB_C PF06430.7 CAR30541.1 - 0.58 10.2 4.4 0.41 10.7 0.5 2.4 2 1 0 2 2 2 0 Lactococcus lactis RepB C-terminus ALS_ss_C PF10369.4 CAR30542.1 - 3e-19 68.5 0.0 1.6e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 CAR30542.1 - 8.5e-12 44.2 0.6 1.7e-11 43.3 0.1 1.8 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 CAR30542.1 - 5.6e-09 35.6 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 CAR30542.1 - 0.063 13.6 0.0 0.5 10.7 0.0 2.1 2 0 0 2 2 2 0 ACT domain PLDc_2 PF13091.1 CAR30544.1 - 7.4e-18 64.5 0.0 2.8e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CAR30544.1 - 3.1e-12 45.8 0.4 3.2e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Rer1 PF03248.8 CAR30545.1 - 3.9e-76 254.5 4.8 4.4e-76 254.3 3.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF4191 PF13829.1 CAR30545.1 - 0.18 10.9 0.3 3.8 6.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) eRF1_2 PF03464.10 CAR30546.1 - 4.4e-31 107.9 0.1 7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CAR30546.1 - 1.6e-24 86.3 0.0 9.7e-24 83.8 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 CAR30546.1 - 3e-14 52.7 0.0 4.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Septin PF00735.13 CAR30547.1 - 8.4e-107 356.3 0.7 9.9e-107 356.1 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CAR30547.1 - 8.2e-09 35.4 0.1 1.5e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CAR30547.1 - 1.2e-07 31.3 0.5 1.2e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CAR30547.1 - 2.6e-07 29.9 0.1 4.9e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CAR30547.1 - 6.1e-06 25.4 0.3 1.1e-05 24.7 0.2 1.5 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CAR30547.1 - 5.2e-05 23.1 1.2 0.07 12.9 0.2 2.5 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 CAR30547.1 - 0.00098 18.6 0.3 0.003 17.0 0.1 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 CAR30547.1 - 0.001 19.5 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 CAR30547.1 - 0.0016 18.7 0.4 0.0035 17.6 0.3 1.7 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CAR30547.1 - 0.003 17.5 0.2 0.0047 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 CAR30547.1 - 0.0037 16.7 0.2 0.0068 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 CAR30547.1 - 0.0046 17.2 0.2 0.0069 16.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CAR30547.1 - 0.0053 16.3 0.1 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CAR30547.1 - 0.0054 16.4 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CAR30547.1 - 0.006 16.4 0.6 0.035 13.9 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CAR30547.1 - 0.0098 16.0 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain IIGP PF05049.8 CAR30547.1 - 0.016 14.0 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 CAR30547.1 - 0.023 14.2 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CAR30547.1 - 0.035 12.9 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.7 CAR30547.1 - 0.07 12.2 0.7 0.54 9.3 0.5 2.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 CAR30547.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CAR30547.1 - 0.079 12.2 0.3 2.7 7.2 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B ArgK PF03308.11 CAR30547.1 - 0.1 11.3 0.1 0.52 9.0 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Ribosomal_L32p PF01783.18 CAR30548.1 - 5.1e-10 39.3 5.7 1.1e-09 38.2 3.9 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family Elongin_A PF06881.6 CAR30548.1 - 0.0057 17.0 0.3 0.01 16.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Cupin_8 PF13621.1 CAR30549.1 - 1.1e-10 41.5 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CAR30549.1 - 1.3e-10 41.4 0.0 3.7e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 CAR30549.1 - 0.00025 20.7 0.1 0.00025 20.7 0.1 2.3 2 0 0 2 2 2 1 F-box-like Cupin_2 PF07883.6 CAR30549.1 - 0.0083 15.6 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain GPI PF06560.6 CAR30549.1 - 0.034 13.1 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) FMN_red PF03358.10 CAR30550.1 - 1.4e-10 40.8 0.0 2.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CAR30550.1 - 4e-09 36.6 0.0 7.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 CAR30550.1 - 3.1e-05 23.5 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 CAR30550.1 - 0.0077 16.2 0.0 0.037 14.0 0.0 2.0 1 1 1 2 2 2 1 Flavodoxin domain Citrate_synt PF00285.16 CAR30551.1 - 6.4e-102 340.9 0.0 7.5e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Pkinase PF00069.20 CAR30552.1 - 6.8e-65 218.7 0.0 1.2e-64 217.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CAR30552.1 - 7e-26 90.8 0.0 9.8e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CAR30552.1 - 0.0016 17.5 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CAR30552.1 - 0.011 15.5 0.1 0.025 14.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CAR30552.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CAR30552.1 - 0.021 14.3 0.1 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sterol-sensing PF12349.3 CAR30553.1 - 0.0001 21.8 9.7 0.00087 18.7 6.7 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Tir_receptor_C PF07489.6 CAR30553.1 - 0.083 12.6 0.2 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus BAR PF03114.13 CAR30554.1 - 2.8e-53 180.8 0.5 3.6e-53 180.4 0.4 1.1 1 0 0 1 1 1 1 BAR domain DUF3114 PF11311.3 CAR30554.1 - 0.068 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) FIVAR PF07554.8 CAR30554.1 - 0.58 10.4 3.9 1.2 9.4 0.1 3.3 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain Seryl_tRNA_N PF02403.17 CAR30554.1 - 0.76 9.8 6.7 7.6 6.6 0.2 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.1 CAR30554.1 - 1.9 8.6 6.7 5.5 7.2 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) S-methyl_trans PF02574.11 CAR30555.1 - 3.6e-51 174.2 0.0 4.2e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase RNA_pol_Rpc34 PF05158.7 CAR30556.1 - 7.5e-95 317.8 0.5 8.9e-95 317.5 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 CAR30556.1 - 0.01 15.8 0.6 0.029 14.4 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator B-block_TFIIIC PF04182.7 CAR30556.1 - 0.013 15.2 0.5 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_36 PF13730.1 CAR30556.1 - 0.12 12.5 1.0 0.81 9.8 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain ABC2_membrane PF01061.19 CAR30557.1 - 4.5e-38 130.5 20.0 4.5e-38 130.5 13.9 2.4 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 CAR30557.1 - 2.3e-29 102.4 0.0 3.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 CAR30557.1 - 0.0011 18.2 0.4 0.0028 16.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CAR30557.1 - 0.002 17.5 0.1 0.25 10.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CAR30557.1 - 0.0055 16.2 0.2 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CAR30557.1 - 0.0081 16.1 0.1 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 CAR30557.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CAR30557.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CAR30557.1 - 0.083 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CAR30557.1 - 0.16 11.5 0.2 0.35 10.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 hEGF PF12661.2 CAR30557.1 - 1 9.5 22.3 0.72 10.0 2.8 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_2 PF07974.8 CAR30557.1 - 1.1 9.4 28.7 0.018 15.2 4.9 4.3 4 0 0 4 4 4 0 EGF-like domain Peptidase_M28 PF04389.12 CAR30558.1 - 1.6e-38 132.2 0.0 2.2e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PIP5K PF01504.13 CAR30559.1 - 5.3e-67 225.5 3.1 5.3e-67 225.5 2.1 2.6 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CAR30559.1 - 1.5e-25 89.7 0.3 3.4e-25 88.6 0.2 1.5 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CAR30559.1 - 3.9e-17 61.9 10.7 3.9e-17 61.9 7.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.27 CAR30560.1 - 3.7e-09 36.0 0.0 0.0046 16.8 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Arrestin_C PF02752.17 CAR30561.1 - 5.1e-24 84.9 0.5 2.7e-23 82.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CAR30561.1 - 8.3e-11 41.9 0.1 4e-09 36.4 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CAR30561.1 - 0.0024 17.4 0.2 0.0073 15.8 0.0 1.9 3 0 0 3 3 3 1 Arrestin_N terminal like rpo132 PF12415.3 CAR30561.1 - 0.076 11.9 0.1 0.18 10.7 0.1 1.6 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase DUF1963 PF09234.5 CAR30562.1 - 5.1e-59 200.2 3.7 6.2e-59 199.9 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) Pyr_redox_2 PF07992.9 CAR30563.1 - 2e-21 76.7 0.0 3.9e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR30563.1 - 3.4e-13 49.7 0.0 1.8e-10 41.0 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.17 CAR30564.1 - 2.8e-38 129.4 2.2 5.2e-13 48.4 0.1 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CAR30564.1 - 1.9e-26 91.8 0.4 7.2e-09 35.4 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CAR30564.1 - 8e-19 67.2 0.3 2.8e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CAR30564.1 - 8e-06 25.5 0.1 0.086 12.6 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CAR30564.1 - 0.045 13.5 0.1 7.5 6.4 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif DUF500 PF04366.7 CAR30565.1 - 6.7e-45 151.6 0.1 1e-44 151.0 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CAR30565.1 - 5.3e-18 64.1 0.1 1.2e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CAR30565.1 - 2.8e-15 55.6 0.1 6.2e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CAR30565.1 - 3.8e-13 48.6 0.0 7e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1776 PF08643.5 CAR30566.1 - 3.6e-36 124.8 9.2 2.5e-34 118.7 6.4 2.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) tRNA-synt_2 PF00152.15 CAR30567.1 - 2.4e-74 250.1 0.0 4e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR30567.1 - 1e-10 41.2 0.0 2.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ProRS-C_1 PF09180.6 CAR30568.1 - 2.1e-26 91.6 2.7 4.1e-26 90.6 1.9 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CAR30568.1 - 4.9e-21 75.0 0.1 7.7e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CAR30568.1 - 1.8e-17 63.0 0.0 4.5e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 CAR30568.1 - 0.039 13.8 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain PHP PF02811.14 CAR30569.1 - 1.9e-20 73.4 0.2 4.2e-20 72.2 0.2 1.5 1 1 0 1 1 1 1 PHP domain DAO PF01266.19 CAR30570.1 - 5.3e-18 65.0 0.0 8.1e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase BRCT PF00533.21 CAR30570.1 - 0.048 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Acetyltransf_13 PF13880.1 CAR30571.1 - 2.5e-19 68.7 0.0 5.7e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 CAR30571.1 - 2.7e-12 46.0 0.2 4.6e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 CAR30571.1 - 2.2e-06 27.5 0.0 6.1e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CAR30571.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CAR30571.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 CAR30571.1 - 0.028 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CAR30571.1 - 0.079 13.1 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CAR30571.1 - 0.09 12.9 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPn PF14671.1 CAR30572.1 - 1.4e-49 167.7 0.0 3.8e-49 166.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CAR30572.1 - 1.7e-23 82.6 0.0 5.1e-22 77.8 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CAR30572.1 - 0.00011 21.6 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CAR30572.1 - 0.0053 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 CAR30572.1 - 0.0094 15.4 0.2 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CAR30572.1 - 0.066 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family SNARE PF05739.14 CAR30573.1 - 3.3e-17 61.9 1.9 3.3e-17 61.9 1.3 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CAR30573.1 - 0.00018 21.6 3.4 0.00018 21.6 2.3 2.5 1 1 1 2 2 2 1 Syntaxin DUF3357 PF11837.3 CAR30573.1 - 0.016 15.0 0.3 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) SUR7 PF06687.7 CAR30574.1 - 1.9e-16 60.2 18.5 2.9e-16 59.7 12.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Sod_Cu PF00080.15 CAR30574.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) DUF1690 PF07956.6 CAR30575.1 - 2e-42 144.5 11.2 2.3e-42 144.3 7.8 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.8 CAR30575.1 - 0.021 14.7 0.4 0.043 13.7 0.2 1.5 1 0 0 1 1 1 0 CHCH domain GerPC PF10737.4 CAR30575.1 - 0.097 12.4 1.0 0.16 11.7 0.3 1.6 1 1 0 2 2 2 0 Spore germination protein GerPC CCDC-167 PF15188.1 CAR30575.1 - 1.2 9.0 5.1 2.7 7.9 3.6 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 UCH PF00443.24 CAR30576.1 - 1.4e-53 181.7 2.5 1.8e-53 181.4 1.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CAR30576.1 - 1.4e-19 70.6 11.4 3e-19 69.5 7.9 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sugar_tr PF00083.19 CAR30577.1 - 2.8e-115 385.4 25.1 3.6e-115 385.1 17.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30577.1 - 2.7e-25 88.8 36.8 5.6e-21 74.6 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.16 CAR30578.1 - 2.7e-118 395.3 42.4 3.1e-118 395.1 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CAR30578.1 - 1.3e-31 109.5 42.5 1.6e-31 109.2 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 CAR30578.1 - 0.29 9.5 0.4 0.43 8.9 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) RNB PF00773.14 CAR30579.1 - 1.4e-93 313.7 0.0 1.9e-93 313.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CAR30579.1 - 9.1e-13 48.4 0.3 2.1e-12 47.2 0.2 1.7 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CAR30579.1 - 0.0021 17.5 0.0 0.0057 16.1 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain ABC_tran PF00005.22 CAR30580.1 - 1.9e-46 157.7 0.4 2.4e-22 79.7 0.0 3.3 3 1 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CAR30580.1 - 3.3e-20 71.7 10.2 3.3e-20 71.7 7.0 3.1 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 CAR30580.1 - 2.5e-18 67.0 13.7 7.4e-06 26.1 0.2 5.3 3 2 1 5 5 5 3 AAA domain AAA_17 PF13207.1 CAR30580.1 - 7.4e-12 46.1 0.4 0.00017 22.4 0.0 3.4 4 0 0 4 4 2 2 AAA domain SMC_N PF02463.14 CAR30580.1 - 2.6e-10 39.9 3.6 0.00041 19.6 0.1 3.9 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 CAR30580.1 - 2.4e-08 34.3 6.2 0.0049 17.1 0.0 4.8 5 1 0 5 5 5 2 AAA domain AAA_28 PF13521.1 CAR30580.1 - 2.5e-08 34.0 0.0 0.0041 17.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAR30580.1 - 7.2e-08 32.6 0.1 0.0073 16.3 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CAR30580.1 - 3.6e-07 30.3 0.1 0.043 13.9 0.0 3.5 4 1 0 4 4 2 2 AAA domain NACHT PF05729.7 CAR30580.1 - 6.7e-07 29.1 0.0 0.0053 16.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 CAR30580.1 - 7.2e-07 29.7 0.0 0.069 13.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 CAR30580.1 - 1.4e-06 27.6 22.3 0.0094 15.0 0.0 5.9 3 2 2 6 6 6 3 AAA ATPase domain MobB PF03205.9 CAR30580.1 - 3.2e-06 26.9 0.0 0.023 14.4 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CAR30580.1 - 3.5e-06 26.9 0.0 0.055 13.3 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CAR30580.1 - 4.7e-06 26.0 0.0 0.14 11.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CAR30580.1 - 6.9e-06 25.3 0.0 0.066 12.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 CAR30580.1 - 1e-05 25.4 0.1 0.027 14.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain ATP-synt_ab PF00006.20 CAR30580.1 - 1.2e-05 24.9 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 CAR30580.1 - 2.7e-05 24.3 0.0 0.11 12.6 0.0 3.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CAR30580.1 - 4.5e-05 23.3 0.0 0.14 12.1 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 CAR30580.1 - 0.00011 22.0 0.1 0.36 10.7 0.1 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CAR30580.1 - 0.00013 22.0 0.3 0.34 11.1 0.0 3.5 4 0 0 4 4 3 1 RNA helicase AAA_10 PF12846.2 CAR30580.1 - 0.00016 21.2 1.9 0.85 8.9 0.0 3.8 4 1 0 4 4 4 2 AAA-like domain AAA_23 PF13476.1 CAR30580.1 - 0.0002 21.7 36.8 0.061 13.6 0.0 5.5 4 1 1 5 5 4 3 AAA domain PduV-EutP PF10662.4 CAR30580.1 - 0.0003 20.2 0.1 0.22 10.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 CAR30580.1 - 0.00069 19.0 0.0 0.61 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CAR30580.1 - 0.00073 18.4 0.1 1.1 8.0 0.0 2.7 2 1 0 2 2 2 2 NB-ARC domain ArgK PF03308.11 CAR30580.1 - 0.00087 18.1 0.2 0.47 9.1 0.0 3.0 2 1 1 3 3 3 1 ArgK protein Septin PF00735.13 CAR30580.1 - 0.0023 17.0 0.0 1.1 8.2 0.0 2.6 2 0 0 2 2 2 1 Septin FtsK_SpoIIIE PF01580.13 CAR30580.1 - 0.0036 16.8 0.0 0.62 9.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 CAR30580.1 - 0.0048 16.2 0.0 0.07 12.4 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein NTPase_1 PF03266.10 CAR30580.1 - 0.0051 16.5 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 NTPase T2SE PF00437.15 CAR30580.1 - 0.0057 15.5 0.0 0.2 10.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.1 CAR30580.1 - 0.0072 15.9 0.0 3.4 7.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 CAR30580.1 - 0.012 15.0 0.0 1.8 7.9 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 CAR30580.1 - 0.015 15.0 0.0 10 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 CAR30580.1 - 0.016 14.7 0.0 0.58 9.6 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.18 CAR30580.1 - 0.021 14.6 12.8 3.7 7.3 5.9 3.8 3 1 0 3 3 2 0 Dynamin family Arch_ATPase PF01637.13 CAR30580.1 - 0.035 13.7 12.8 0.16 11.6 0.0 3.6 5 0 0 5 5 3 0 Archaeal ATPase SRP54 PF00448.17 CAR30580.1 - 0.062 12.7 0.4 2.6 7.4 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Ras PF00071.17 CAR30580.1 - 0.081 12.3 1.3 10 5.4 0.0 3.3 3 0 0 3 3 3 0 Ras family DUF87 PF01935.12 CAR30580.1 - 0.33 10.7 0.0 0.33 10.7 0.0 5.2 5 1 1 6 6 6 0 Domain of unknown function DUF87 NPV_P10 PF05531.7 CAR30580.1 - 2.9 8.2 5.4 18 5.6 0.3 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PDCD2_C PF04194.8 CAR30581.1 - 2.7e-45 153.8 0.1 1.3e-41 141.9 0.0 2.5 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain GTP_EFTU PF00009.22 CAR30582.1 - 2.3e-35 121.7 2.0 3.1e-34 118.0 1.4 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CAR30582.1 - 3e-21 75.3 0.5 9.6e-21 73.7 0.4 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CAR30582.1 - 4.1e-10 39.6 7.8 1.6e-06 28.1 0.1 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 IF2_N PF04760.10 CAR30582.1 - 1.7e-08 34.0 0.0 4.6e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 CAR30582.1 - 4.5e-07 29.8 0.5 2.8e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CAR30582.1 - 1.3e-05 25.6 0.1 4.3e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CAR30582.1 - 0.0064 15.9 0.1 0.064 12.6 0.0 2.3 2 0 0 2 2 2 1 Ras family PduV-EutP PF10662.4 CAR30582.1 - 0.015 14.7 1.0 0.12 11.9 0.2 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CAR30582.1 - 0.073 12.8 7.7 4 7.2 0.0 4.3 4 2 1 5 5 5 0 Dynamin family DUF1018 PF06252.7 CAR30582.1 - 0.094 13.2 0.0 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Iron_permease PF04120.7 CAR30583.1 - 6.9e-31 106.5 16.2 1.1e-15 57.4 1.9 4.5 4 0 0 4 4 4 4 Low affinity iron permease TauD PF02668.11 CAR30584.1 - 2.9e-41 141.8 0.0 3.9e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 CAR30584.1 - 0.0013 17.6 0.0 0.7 8.7 0.0 2.3 2 0 0 2 2 2 2 CsiD DUF971 PF06155.7 CAR30584.1 - 0.026 14.9 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 CAR30584.1 - 0.11 12.9 0.0 2.4 8.7 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily TIP120 PF08623.5 CAR30586.1 - 9.9e-09 34.9 0.0 2.5e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) PGK PF00162.14 CAR30587.1 - 7.8e-154 511.8 0.5 8.8e-154 511.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DNA_pol_B_palm PF14792.1 CAR30588.1 - 6.1e-20 71.3 0.0 1.8e-19 69.8 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 CAR30588.1 - 1e-19 69.9 0.0 2.6e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 CAR30588.1 - 4.9e-15 55.4 0.0 3e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CAR30588.1 - 1.7e-12 46.6 0.1 4.2e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 CAR30588.1 - 0.0029 17.8 0.0 0.0072 16.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT PF00533.21 CAR30588.1 - 0.066 13.3 0.0 0.32 11.1 0.0 2.2 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain HAD PF12710.2 CAR30589.1 - 1.8e-07 31.5 0.0 2.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2373 PF10180.4 CAR30590.1 - 3.7e-23 80.8 0.0 6e-23 80.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Sugar_tr PF00083.19 CAR30591.1 - 4.8e-106 355.0 25.3 6.1e-106 354.7 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CAR30591.1 - 1e-26 93.5 27.0 1.3e-26 93.1 10.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CAR30591.1 - 0.068 11.5 32.7 0.014 13.8 7.7 3.8 3 2 0 4 4 4 0 MFS/sugar transport protein Frag1 PF10277.4 CAR30593.1 - 1.8e-35 122.3 11.2 1.8e-35 122.3 7.8 3.5 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 CAR30593.1 - 0.0015 18.5 0.0 0.0032 17.4 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Alpha-amylase_C PF02806.13 CAR30594.1 - 1.4e-24 85.9 0.2 3.9e-24 84.6 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CAR30594.1 - 3.8e-17 62.6 0.3 2.6e-16 59.9 0.0 2.3 2 1 1 3 3 3 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 CAR30594.1 - 3.6e-14 52.5 0.0 7.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) UQ_con PF00179.21 CAR30595.1 - 5.6e-39 132.7 0.1 7.1e-39 132.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CAR30595.1 - 0.041 13.7 0.0 0.058 13.2 0.0 1.5 1 1 0 1 1 1 0 RWD domain BUD22 PF09073.5 CAR30595.1 - 3.6 6.5 9.2 4.1 6.3 6.3 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CAR30595.1 - 5 4.9 20.8 5.8 4.7 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family Phasin PF05597.6 CAR30596.1 - 0.084 12.6 0.2 0.094 12.4 0.1 1.3 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2559 PF10832.3 CAR30596.1 - 2.1 8.2 5.5 19 5.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) TENA_THI-4 PF03070.11 CAR30597.1 - 1.7e-12 47.5 1.7 2.4e-12 47.0 1.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CAR30598.1 - 9.2e-06 24.9 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Arm PF00514.18 CAR30599.1 - 2.8e-67 220.4 33.2 8.2e-11 41.3 0.1 11.0 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CAR30599.1 - 2.9e-23 81.9 11.4 1.1e-05 25.5 0.2 7.2 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 CAR30599.1 - 3.6e-16 59.1 16.8 5.4e-06 26.7 0.3 7.8 6 1 3 9 9 8 5 HEAT-like repeat HEAT PF02985.17 CAR30599.1 - 1e-13 50.1 27.9 0.11 12.6 0.1 10.5 11 0 0 11 11 11 4 HEAT repeat Adaptin_N PF01602.15 CAR30599.1 - 2.7e-12 45.7 9.6 1e-06 27.4 1.5 2.7 1 1 2 3 3 3 2 Adaptin N terminal region KAP PF05804.7 CAR30599.1 - 4.1e-09 34.9 0.8 8e-07 27.3 0.0 2.6 1 1 2 3 3 3 2 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CAR30599.1 - 5e-08 32.3 10.3 2.6e-06 26.7 3.0 3.1 2 1 0 3 3 3 2 Armadillo-like Vac14_Fab1_bd PF12755.2 CAR30599.1 - 0.00011 22.4 1.5 0.2 12.0 0.0 4.0 2 2 1 4 4 4 1 Vacuolar 14 Fab1-binding region V-ATPase_H_N PF03224.9 CAR30599.1 - 0.00017 20.7 4.0 0.0015 17.7 0.3 3.1 1 1 0 2 2 2 1 V-ATPase subunit H DUF2454 PF10521.4 CAR30599.1 - 0.00021 20.4 0.2 0.024 13.6 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF2454) RIX1 PF08167.7 CAR30599.1 - 0.00041 20.0 3.3 0.039 13.6 0.1 3.5 2 1 1 3 3 3 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 CAR30599.1 - 0.059 13.2 7.0 0.67 9.7 0.1 4.5 2 2 3 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 CAR30599.1 - 0.077 12.8 0.6 8.1 6.4 0.0 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF2435) V-ATPase_H_C PF11698.3 CAR30599.1 - 0.1 12.5 6.8 0.35 10.7 0.1 4.3 3 2 4 7 7 7 0 V-ATPase subunit H YjeF_N PF03853.10 CAR30600.1 - 3.6e-29 101.5 0.2 1.2e-28 99.8 0.0 1.9 2 0 0 2 2 2 1 YjeF-related protein N-terminus FDF PF09532.5 CAR30600.1 - 1.9e-07 31.5 6.4 3.5e-07 30.6 4.5 1.5 1 0 0 1 1 1 1 FDF domain Ras PF00071.17 CAR30601.1 - 2.7e-42 143.9 0.0 3.1e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CAR30601.1 - 7.1e-15 55.5 0.2 8.9e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CAR30601.1 - 1.8e-09 37.0 0.0 2.1e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CAR30601.1 - 6.9e-08 32.1 0.4 4.5e-06 26.2 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CAR30601.1 - 9.6e-08 31.9 0.2 1.3e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CAR30601.1 - 0.00069 18.8 0.2 0.0009 18.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CAR30601.1 - 0.00081 18.6 0.1 0.008 15.4 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 CAR30601.1 - 0.018 14.9 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CAR30601.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase adh_short_C2 PF13561.1 CAR30602.1 - 3e-20 73.0 0.1 7.1e-20 71.7 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CAR30602.1 - 9.2e-19 67.9 0.8 3e-17 63.0 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CAR30602.1 - 4.6e-10 39.4 0.3 1.3e-09 38.0 0.2 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CAR30602.1 - 1.9e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CAR30602.1 - 0.00028 19.8 0.0 0.00038 19.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CAR30602.1 - 0.032 12.9 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CAR30602.1 - 0.078 13.4 0.0 1.5 9.2 0.0 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 CAR30602.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4128 PF13554.1 CAR30604.1 - 0.026 14.1 0.0 0.41 10.2 0.0 2.4 2 1 0 3 3 3 0 Bacteriophage related domain of unknown function zf-Nse PF11789.3 CAR30605.1 - 1.6e-20 72.3 0.7 6.7e-20 70.3 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CAR30605.1 - 0.00014 21.5 1.2 0.00042 19.9 0.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CAR30605.1 - 0.001 18.8 1.4 0.0021 17.8 0.5 1.9 1 1 1 2 2 2 1 Ring finger domain Rtf2 PF04641.7 CAR30605.1 - 0.016 14.3 0.1 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger zf-rbx1 PF12678.2 CAR30605.1 - 0.026 14.6 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CAR30605.1 - 0.031 14.1 1.1 0.055 13.3 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CAR30605.1 - 0.044 13.4 0.3 0.087 12.4 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 CAR30605.1 - 0.045 13.2 0.8 0.045 13.2 0.6 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 CAR30605.1 - 0.28 10.9 1.4 0.51 10.0 1.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CAR30605.1 - 0.31 11.1 1.9 0.59 10.2 1.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_2 PF00152.15 CAR30606.1 - 1.7e-73 247.3 0.0 2e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CAR30606.1 - 6.3e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CAR30606.1 - 0.009 15.2 0.0 3.5 6.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TPP_enzyme_N PF02776.13 CAR30607.1 - 3.6e-42 143.7 0.1 2.7e-41 140.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CAR30607.1 - 6e-27 94.0 0.1 3e-26 91.8 0.3 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CAR30607.1 - 1.4e-22 79.9 0.0 2.8e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 CAR30607.1 - 0.048 12.5 0.9 0.11 11.4 0.2 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Peripla_BP_4 PF13407.1 CAR30607.1 - 0.13 11.6 1.5 0.41 9.9 0.1 2.3 2 1 0 2 2 2 0 Periplasmic binding protein domain zf-Tim10_DDP PF02953.10 CAR30608.1 - 2.3e-21 74.8 6.7 3.3e-21 74.3 4.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 CAR30608.1 - 0.032 13.2 0.4 0.036 13.1 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Gemini_AL1_M PF08283.6 CAR30608.1 - 0.054 13.3 0.2 0.058 13.2 0.1 1.2 1 0 0 1 1 1 0 Geminivirus rep protein central domain DUF1178 PF06676.6 CAR30608.1 - 0.075 13.2 0.3 0.11 12.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Pepsin-I3 PF06394.8 CAR30608.1 - 0.14 11.8 3.3 0.38 10.4 0.1 2.1 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Vicilin_N PF04702.7 CAR30608.1 - 0.49 10.0 5.8 0.61 9.6 4.0 1.2 1 0 0 1 1 1 0 Vicilin N terminal region DUF842 PF05811.8 CAR30608.1 - 0.56 9.6 8.5 1.2 8.5 5.9 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) OMPdecase PF00215.19 CAR30609.1 - 4.7e-74 248.6 0.0 5.4e-74 248.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mito_carr PF00153.22 CAR30610.1 - 3.1e-13 49.2 0.9 1.4e-08 34.3 0.0 3.1 3 1 0 3 3 3 2 Mitochondrial carrier protein MatK_N PF01824.13 CAR30610.1 - 0.024 13.7 3.4 0.33 10.0 0.4 2.2 2 0 0 2 2 2 0 MatK/TrnK amino terminal region Mob1_phocein PF03637.12 CAR30610.1 - 0.06 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Mob1/phocein family Sec7 PF01369.15 CAR30611.1 - 1.9e-62 210.3 1.6 5.7e-62 208.7 1.1 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CAR30611.1 - 3.3e-16 59.1 2.0 3.3e-16 59.1 1.4 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2683 PF10884.3 CAR30611.1 - 0.0031 17.3 0.3 0.018 14.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2683) Pro_isomerase PF00160.16 CAR30612.1 - 2.2e-38 131.8 0.1 3.5e-38 131.2 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CAR30612.1 - 6e-10 38.6 8.8 0.00026 20.5 1.6 3.0 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CAR30612.1 - 1.8e-09 36.7 19.2 1.3e-07 30.8 0.6 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CAR30612.1 - 6.7e-09 35.0 15.2 4.3e-06 26.2 0.3 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CAR30612.1 - 7.9e-07 29.5 0.4 0.00018 22.1 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CAR30612.1 - 1.3e-05 25.0 3.9 8.1e-05 22.4 0.3 2.8 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CAR30612.1 - 8.5e-05 22.0 15.6 0.0031 17.1 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR30612.1 - 0.00096 18.9 0.0 0.0075 16.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CAR30612.1 - 0.0018 18.3 9.3 0.0093 16.0 5.9 2.5 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CAR30612.1 - 0.026 14.8 0.7 1.5 9.2 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAR30612.1 - 0.03 14.9 0.0 5.1 8.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CAR30612.1 - 0.24 11.9 7.3 0.45 11.0 0.0 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 CAR30612.1 - 0.74 9.7 3.7 1.6 8.6 0.0 2.9 3 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 CAR30612.1 - 0.81 9.5 6.8 1.9 8.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Rav1p_C PF12234.3 CAR30613.1 - 3.5e-231 768.7 4.8 5.8e-231 768.0 1.0 2.1 2 0 0 2 2 2 1 RAVE protein 1 C terminal TFIIIC_delta PF12657.2 CAR30613.1 - 0.029 14.0 0.2 1.4 8.6 0.0 3.2 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 CAR30613.1 - 0.12 12.3 7.6 2.1 8.3 0.0 5.1 5 1 0 5 5 5 0 WD domain, G-beta repeat Pet191_N PF10203.4 CAR30614.1 - 4e-26 90.8 4.2 5.3e-26 90.4 2.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CAR30614.1 - 0.31 10.8 3.8 5.5 6.8 0.1 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CAR30614.1 - 0.85 9.6 3.4 0.38 10.7 0.5 1.9 2 0 0 2 2 2 0 CHCH domain SNF2_N PF00176.18 CAR30615.1 - 1.1e-77 260.8 0.0 1.8e-77 260.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CAR30615.1 - 3.8e-15 55.5 0.0 1.8e-14 53.3 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Allexi_40kDa PF05549.6 CAR30615.1 - 0.43 9.8 3.9 0.99 8.6 2.7 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2235 PF09994.4 CAR30616.1 - 5.4e-83 278.5 0.0 9.3e-83 277.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) UCR_TM PF02921.9 CAR30617.1 - 1.2e-22 79.8 2.1 2.2e-22 79.0 1.4 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CAR30617.1 - 6e-18 64.2 0.1 1.4e-17 63.0 0.0 1.6 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain Transp_cyt_pur PF02133.10 CAR30617.1 - 0.1 11.1 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin HECT PF00632.20 CAR30618.1 - 1.8e-78 263.8 0.6 7.1e-78 261.9 0.1 2.1 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Ribosomal_L7Ae PF01248.21 CAR30620.1 - 9.6e-28 95.5 0.0 1.1e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CAR30620.1 - 0.0099 15.7 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 CAR30620.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Voltage_CLC PF00654.15 CAR30621.1 - 3.5e-77 259.8 26.5 3.5e-77 259.8 18.3 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CAR30621.1 - 1.9e-06 27.5 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 2 CBS domain Urb2 PF10441.4 CAR30622.1 - 8.6e-58 195.5 4.0 4.1e-57 193.3 0.6 3.4 2 1 0 2 2 2 1 Urb2/Npa2 family Methyltransf_2 PF00891.13 CAR30622.1 - 0.0071 15.5 0.1 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase DUF310 PF03750.8 CAR30622.1 - 0.012 15.7 0.3 0.4 10.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF310) Nucleopor_Nup85 PF07575.8 CAR30623.1 - 5.1e-146 487.1 6.4 5.9e-146 486.9 4.5 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin ATP-synt_C PF00137.16 CAR30624.1 - 2.2e-32 110.7 27.7 9e-19 67.1 7.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 CAR30624.1 - 1.5 8.2 4.1 17 4.9 0.1 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DUF2970 PF11174.3 CAR30624.1 - 4.5 6.9 8.4 0.82 9.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) CDC27 PF09507.5 CAR30625.1 - 7e-10 38.7 0.6 7e-10 38.7 0.4 2.4 2 0 0 2 2 2 2 DNA polymerase subunit Cdc27 adh_short PF00106.20 CAR30626.1 - 5.5e-26 91.4 1.4 1.3e-25 90.2 0.9 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CAR30626.1 - 1.4e-22 80.6 0.0 1.8e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CAR30626.1 - 9.3e-12 44.9 0.4 3.9e-11 42.9 0.4 1.7 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 CAR30626.1 - 2.7e-05 23.0 0.2 5e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CAR30626.1 - 5.7e-05 22.6 0.1 0.00052 19.5 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 CAR30626.1 - 0.042 14.2 0.1 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 CAR30626.1 - 0.11 12.1 0.2 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phos_pyr_kin PF08543.7 CAR30627.1 - 1.3e-11 44.2 0.0 1.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CAR30627.1 - 8e-11 41.6 0.0 7.2e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase MaoC_dehydrat_N PF13452.1 CAR30628.1 - 0.094 12.4 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase Ins_P5_2-kin PF06090.7 CAR30629.1 - 3.7e-43 147.7 1.0 9.4e-43 146.4 0.7 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DS PF01916.12 CAR30630.1 - 3.1e-145 482.8 0.0 3.8e-145 482.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Methyltransf_23 PF13489.1 CAR30631.1 - 3.5e-16 59.3 0.0 5.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CAR30631.1 - 7.3e-12 45.6 0.4 2.8e-11 43.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 CAR30631.1 - 9.2e-09 34.7 0.0 3e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CAR30631.1 - 1.8e-08 34.7 0.0 6.1e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CAR30631.1 - 4.9e-08 32.6 0.0 1.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CAR30631.1 - 1.5e-07 31.9 0.1 5.9e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CAR30631.1 - 1.4e-06 28.5 0.0 3.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ECR1_N PF14382.1 CAR30632.1 - 1.7e-13 49.6 0.8 5.7e-13 47.9 0.0 2.3 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CAR30632.1 - 0.0019 18.1 0.2 0.14 12.1 0.0 3.4 3 1 0 3 3 3 1 Exosome component EXOSC1/CSL4 MotA_activ PF09114.5 CAR30632.1 - 0.039 13.6 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Transcription factor MotA, activation domain Met_10 PF02475.11 CAR30633.1 - 6.8e-73 244.5 0.0 1.1e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 CAR30633.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cyclin PF08613.6 CAR30634.1 - 1.6e-11 44.8 0.6 2e-11 44.4 0.4 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CAR30634.1 - 6.6e-10 38.6 1.7 1e-09 38.0 1.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain HIM1 PF08732.5 CAR30635.1 - 2.9e-57 194.0 0.0 2.8e-56 190.7 0.0 1.9 1 1 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.1 CAR30635.1 - 0.008 16.1 0.1 1.8 8.5 0.1 2.3 2 0 0 2 2 2 2 NADH(P)-binding CENP-O PF09496.5 CAR30636.1 - 2.7e-18 65.9 0.2 6.2e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DUF2408 PF10303.4 CAR30636.1 - 0.9 9.6 3.7 0.68 10.0 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Scs3p PF10261.4 CAR30637.1 - 3.5e-39 134.2 11.0 1.5e-38 132.2 7.6 2.0 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 CAR30637.1 - 0.0027 17.4 3.4 0.004 16.8 2.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily Orai-1 PF07856.7 CAR30637.1 - 0.03 13.8 1.2 0.049 13.2 0.8 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF588 PF04535.7 CAR30637.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF588) DUF843 PF05814.6 CAR30637.1 - 0.15 11.8 4.3 1.7 8.4 0.0 3.3 4 0 0 4 4 4 0 Baculovirus protein of unknown function (DUF843) Prenyltrans_2 PF13249.1 CAR30638.1 - 6.1e-32 110.3 0.1 1.9e-14 54.0 0.0 5.2 2 1 3 5 5 5 4 Prenyltransferase-like Prenyltrans PF00432.16 CAR30638.1 - 2.3e-28 97.4 2.0 3.2e-10 39.3 0.2 4.9 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CAR30638.1 - 3.9e-21 75.1 0.0 1.1e-13 51.1 0.0 5.7 2 2 4 6 6 6 3 Prenyltransferase-like Pec_lyase PF09492.5 CAR30638.1 - 0.0018 17.5 0.2 1.2 8.1 0.1 3.4 2 1 2 4 4 4 2 Pectic acid lyase Ubiq-assoc PF09145.5 CAR30639.1 - 3.7e-22 77.9 0.8 3.7e-22 77.9 0.6 1.9 2 0 0 2 2 1 1 Ubiquitin-associated TPR_11 PF13414.1 CAR30639.1 - 5e-14 51.7 0.5 8.2e-07 28.5 0.0 4.2 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.1 CAR30639.1 - 8.3e-10 38.4 1.7 0.0011 18.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CAR30639.1 - 1.6e-08 33.7 8.6 0.006 16.1 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CAR30639.1 - 7.4e-08 31.7 7.7 0.086 12.7 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CAR30639.1 - 2.5e-07 29.9 2.9 0.0065 16.1 0.1 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CAR30639.1 - 0.00031 20.5 0.1 9.1 6.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DnaJ PF00226.26 CAR30639.1 - 0.00067 19.3 0.1 0.0017 18.0 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain MIT PF04212.13 CAR30639.1 - 0.0018 18.1 3.3 0.82 9.5 0.2 3.9 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 CAR30639.1 - 0.024 15.0 6.2 1.1 9.8 0.1 3.8 5 0 0 5 5 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CAR30639.1 - 0.043 13.0 1.5 4.2 6.7 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR TPR_8 PF13181.1 CAR30639.1 - 0.073 12.8 7.6 4.1 7.4 0.2 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CAR30639.1 - 0.17 12.6 0.4 15 6.5 0.0 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CAR30639.1 - 0.21 11.5 0.7 9 6.3 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Nop10p PF04135.7 CAR30640.1 - 6e-22 77.1 0.4 7.4e-22 76.8 0.3 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DASH_Dad4 PF08650.5 CAR30641.1 - 1.6e-36 123.9 7.2 1.8e-36 123.8 5.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 NPV_P10 PF05531.7 CAR30641.1 - 0.0031 17.7 0.3 0.0036 17.5 0.2 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF3251 PF11622.3 CAR30641.1 - 0.0059 16.0 0.8 0.0072 15.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3251) BCAS2 PF05700.6 CAR30641.1 - 0.021 14.3 1.0 0.022 14.2 0.7 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF4206 PF13901.1 CAR30641.1 - 0.039 13.5 0.5 0.044 13.3 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Pox_A32 PF04665.7 CAR30641.1 - 0.09 12.0 1.2 0.11 11.8 0.8 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein DASH_Dad3 PF08656.5 CAR30641.1 - 0.091 12.4 0.4 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad3 FbpA PF05833.6 CAR30641.1 - 0.092 11.2 0.2 0.1 11.0 0.1 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Nsp1_C PF05064.8 CAR30641.1 - 0.097 12.3 0.5 0.11 12.1 0.4 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF1955 PF09205.5 CAR30641.1 - 0.098 12.1 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) DUF1830 PF08865.6 CAR30641.1 - 0.11 12.1 0.1 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) DivIC PF04977.10 CAR30641.1 - 0.15 11.5 1.0 0.21 11.1 0.7 1.2 1 0 0 1 1 1 0 Septum formation initiator DASH_Dam1 PF08653.5 CAR30641.1 - 0.16 11.7 0.5 0.26 11.0 0.3 1.5 1 1 0 1 1 1 0 DASH complex subunit Dam1 Oxysterol_BP PF01237.13 CAR30642.1 - 4.7e-103 344.3 3.0 8.2e-103 343.5 2.1 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CAR30642.1 - 5e-30 103.4 0.7 1.2e-29 102.1 0.2 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CAR30642.1 - 0.0092 16.1 0.4 0.033 14.3 0.3 2.0 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CAR30642.1 - 0.85 9.8 5.5 22 5.3 3.8 3.1 1 1 0 1 1 1 0 Pleckstrin homology domain Asparaginase PF00710.15 CAR30643.1 - 1.4e-68 231.0 0.0 1.7e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Ribosomal_L19 PF01245.15 CAR30643.1 - 0.019 14.7 0.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L19 DIOX_N PF14226.1 CAR30644.1 - 1.8e-15 57.4 0.7 3.8e-15 56.4 0.3 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CAR30644.1 - 1.1e-14 54.4 0.0 2.8e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CN_hydrolase PF00795.17 CAR30645.1 - 3.1e-25 88.6 0.0 5.2e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CAR30645.1 - 2.6e-23 82.1 0.0 1.1e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 CAR30645.1 - 0.0034 16.9 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase PhnG PF06754.7 CAR30645.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Abhydrolase_6 PF12697.2 CAR30646.1 - 2.4e-23 83.2 1.5 3.9e-23 82.5 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CAR30646.1 - 8.7e-10 38.5 0.1 2.2e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CAR30646.1 - 7.8e-08 32.1 0.0 1.5e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CAR30646.1 - 5.3e-06 26.2 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CAR30646.1 - 0.0019 18.4 0.5 0.037 14.2 0.3 2.3 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 CAR30646.1 - 0.0049 16.4 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 CAR30646.1 - 0.052 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase zf-C2H2_4 PF13894.1 CAR30647.1 - 0.0001 22.3 16.2 0.018 15.3 0.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CAR30647.1 - 0.00022 21.3 11.6 0.0023 18.1 1.0 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CAR30647.1 - 0.00037 20.6 2.1 0.00037 20.6 1.4 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-BED PF02892.10 CAR30647.1 - 0.62 9.8 7.5 0.2 11.4 0.4 2.9 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.2 CAR30647.1 - 3.5 7.8 8.1 1.9 8.6 0.1 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.1 CAR30647.1 - 5.4 6.9 8.0 0.95 9.3 0.7 2.4 1 1 1 2 2 2 0 Zinc-finger RGS PF00615.14 CAR30648.1 - 7e-07 29.3 2.0 9.4e-07 28.9 0.2 2.0 2 1 0 2 2 2 1 Regulator of G protein signaling domain YjgP_YjgQ PF03739.9 CAR30648.1 - 0.021 13.5 0.0 0.034 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Usg PF06233.7 CAR30648.1 - 0.11 12.3 1.2 2.7 7.9 0.1 2.8 3 0 0 3 3 3 0 Usg-like family GATase PF00117.23 CAR30649.1 - 7.3e-45 152.7 0.0 1e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 CAR30649.1 - 1.7e-44 150.4 0.0 2.9e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 CAR30649.1 - 1.1e-06 28.2 0.1 0.00098 18.6 0.1 3.1 1 1 1 2 2 2 2 Peptidase C26 DJ-1_PfpI PF01965.19 CAR30649.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Peripla_BP_4 PF13407.1 CAR30649.1 - 0.053 12.8 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain RCC1_2 PF13540.1 CAR30650.1 - 1e-13 50.4 2.6 2.5e-05 23.7 0.1 4.0 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CAR30650.1 - 8.8e-13 48.2 8.3 0.00021 21.4 0.0 4.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CAR30650.1 - 7.5e-11 42.0 1.3 2.1e-06 27.7 0.1 3.3 2 1 1 3 3 3 2 BTB/POZ domain SNF2_N PF00176.18 CAR30651.1 - 5.4e-77 258.5 0.4 8.8e-77 257.8 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CAR30651.1 - 8.2e-42 141.6 2.3 8.2e-42 141.6 1.6 2.8 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 CAR30651.1 - 1.4e-26 93.1 1.0 1.4e-26 93.1 0.7 3.2 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 CAR30651.1 - 9.3e-17 60.6 0.0 3e-16 59.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR30651.1 - 5.6e-08 32.8 0.3 2e-06 27.7 0.0 3.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CAR30651.1 - 6.3e-06 25.7 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 CAR30651.1 - 0.00091 19.2 0.3 0.071 13.1 0.0 3.9 4 0 0 4 4 4 1 Myb-like DNA-binding domain AAA_22 PF13401.1 CAR30651.1 - 0.0045 17.1 0.0 0.023 14.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CAR30651.1 - 0.021 14.7 0.3 0.12 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ribonuclease_3 PF00636.21 CAR30652.1 - 1.1e-18 67.7 0.6 8e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CAR30652.1 - 3.7e-16 59.2 0.4 1.1e-14 54.4 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 CAR30652.1 - 0.00035 21.0 0.0 0.0011 19.5 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif Colicin PF01024.14 CAR30652.1 - 0.08 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Colicin pore forming domain DUF382 PF04037.8 CAR30653.1 - 5.3e-50 168.5 0.1 5.3e-50 168.5 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 CAR30653.1 - 3.8e-18 64.5 1.1 6.5e-18 63.8 0.7 1.4 1 0 0 1 1 1 1 PSP DUF2034 PF10356.4 CAR30654.1 - 4.1e-56 189.0 0.0 5e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CAR30654.1 - 8.5e-05 22.3 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 2 Restriction endonuclease Mito_carr PF00153.22 CAR30655.1 - 1.4e-29 101.5 3.8 1.1e-12 47.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.11 CAR30656.1 - 9.1e-20 70.8 6.9 9.1e-20 70.8 4.8 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CAR30656.1 - 2.5e-06 27.5 23.6 0.0073 16.3 0.2 3.9 3 1 1 4 4 4 3 EamA-like transporter family UAA PF08449.6 CAR30656.1 - 2.5e-05 23.3 18.5 6.2e-05 22.0 1.0 2.9 3 0 0 3 3 3 2 UAA transporter family PIRT PF15099.1 CAR30656.1 - 0.38 9.9 7.1 11 5.2 0.2 3.4 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family DUF3671 PF12420.3 CAR30656.1 - 1.8 8.5 13.4 6.3 6.8 0.4 3.6 2 2 1 3 3 3 0 Protein of unknown function SART-1 PF03343.8 CAR30657.1 - 8.7e-60 202.7 64.6 2e-58 198.2 44.8 2.0 1 1 0 1 1 1 1 SART-1 family BTD PF09270.5 CAR30657.1 - 0.026 14.2 1.9 0.1 12.3 1.3 2.1 1 1 0 1 1 1 0 Beta-trefoil DNA-binding domain Nop PF01798.13 CAR30658.1 - 4.5e-59 198.0 1.4 1.4e-58 196.4 1.0 1.9 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CAR30658.1 - 2.7e-26 91.1 0.0 6e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CAR30658.1 - 8.9e-19 67.4 2.1 8.9e-19 67.4 1.5 2.9 2 1 1 3 3 3 1 NOP5NT (NUC127) domain Aldolase PF01081.14 CAR30658.1 - 0.077 12.1 0.1 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF4604 PF15377.1 CAR30658.1 - 0.26 11.4 43.6 0.053 13.7 27.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) CTP_transf_1 PF01148.15 CAR30659.1 - 3.3e-24 85.9 11.7 1.7e-20 73.7 4.8 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_L18ae PF01775.12 CAR30660.1 - 3.2e-45 153.0 0.7 4.8e-45 152.4 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Cation_efflux PF01545.16 CAR30663.1 - 5.2e-80 268.5 8.3 7.6e-80 268.0 5.8 1.2 1 0 0 1 1 1 1 Cation efflux family NicO PF03824.11 CAR30663.1 - 0.0064 15.8 0.1 0.0064 15.8 0.1 1.8 2 0 0 2 2 2 1 High-affinity nickel-transport protein SUN PF03856.8 CAR30665.1 - 8.8e-81 270.8 17.5 1.1e-80 270.5 12.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Bac_rhodopsin PF01036.13 CAR30666.1 - 4.9e-70 235.3 22.6 5.7e-70 235.0 15.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein COX6B PF02297.12 CAR30667.1 - 3.2e-23 81.5 8.1 4e-23 81.2 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Trp_DMAT PF11991.3 CAR30667.1 - 0.031 13.5 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase Prolamin_like PF05617.6 CAR30667.1 - 0.22 11.6 2.1 0.38 10.9 1.5 1.4 1 1 0 1 1 1 0 Prolamin-like Aminotran_3 PF00202.16 CAR30668.1 - 2e-58 197.8 0.0 2.3e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CAR30668.1 - 0.0069 15.3 0.0 0.07 12.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II FTR_C PF02741.10 CAR30668.1 - 0.095 12.4 0.1 2.9 7.6 0.0 2.8 3 0 0 3 3 3 0 FTR, proximal lobe zf-C3HC4_2 PF13923.1 CAR30669.1 - 7.3 6.7 9.9 30 4.7 6.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.14 CAR30670.1 - 1.2e-21 76.9 10.0 1.4e-21 76.7 7.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Herpes_TK_C PF08465.5 CAR30670.1 - 0.052 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal ACP_syn_III PF08545.5 CAR30670.1 - 0.23 11.1 2.5 0.39 10.4 1.5 1.8 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Shadoo PF14999.1 CAR30670.1 - 0.59 9.9 6.2 0.81 9.5 4.3 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_L13e PF01294.13 CAR30671.1 - 1.2e-69 233.3 3.8 1.7e-69 232.8 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.14 CAR30672.1 - 3.9e-38 130.4 0.3 4.4e-38 130.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyco_trans_1_3 PF13528.1 CAR30672.1 - 0.052 12.7 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 HlyU PF10115.4 CAR30673.1 - 0.024 14.4 0.6 0.2 11.5 0.2 2.3 2 0 0 2 2 2 0 Transcriptional activator HlyU DEAD PF00270.24 CAR30674.1 - 2.1e-34 118.4 0.7 4.2e-34 117.4 0.1 1.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CAR30674.1 - 6.6e-24 83.5 0.0 6.4e-23 80.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CAR30674.1 - 0.00012 21.9 0.1 0.00038 20.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pyr_redox_2 PF07992.9 CAR30675.1 - 7.8e-26 91.1 0.0 2.4e-16 60.2 0.0 3.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CAR30675.1 - 1.3e-13 51.1 0.0 2.1e-12 47.2 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CAR30675.1 - 5e-06 26.7 0.0 0.0035 17.4 0.0 3.1 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CAR30675.1 - 0.11 12.2 0.3 23 4.7 0.0 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding 4F5 PF04419.9 CAR30676.1 - 2e-07 31.6 11.9 2e-07 31.6 8.3 2.2 1 1 1 2 2 2 1 4F5 protein family Dishevelled PF02377.10 CAR30676.1 - 4.1 7.6 7.6 0.23 11.6 1.3 1.7 1 1 1 2 2 2 0 Dishevelled specific domain WD40 PF00400.27 CAR30677.1 - 2.1e-33 112.9 1.7 1.7e-09 37.1 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CAR30677.1 - 2e-06 27.6 0.1 4.8e-05 23.1 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 CAR30677.1 - 0.013 14.8 1.7 0.073 12.4 0.8 2.2 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 CAR30677.1 - 0.051 11.8 0.4 0.23 9.7 0.1 2.1 2 1 1 3 3 3 0 Cytochrome D1 heme domain DLH PF01738.13 CAR30678.1 - 8.4e-28 97.1 0.0 9.6e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CAR30678.1 - 1.7e-06 27.8 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CAR30678.1 - 5.2e-05 22.5 0.1 0.0032 16.7 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF2305 PF10230.4 CAR30678.1 - 0.0026 17.2 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) BAAT_C PF08840.6 CAR30678.1 - 0.032 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.6 CAR30678.1 - 0.05 12.3 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase S-AdoMet_synt_N PF00438.15 CAR30678.1 - 0.082 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain Chlorophyllase2 PF12740.2 CAR30678.1 - 0.14 11.0 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme T5orf172 PF10544.4 CAR30679.1 - 2.2e-06 28.0 0.1 9.7e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 CAR30679.1 - 7e-06 26.4 0.3 0.00021 21.7 0.2 2.3 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 Ribophorin_II PF05817.9 CAR30682.1 - 1.1e-07 30.5 5.4 1.4e-07 30.1 3.7 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_S24 PF00717.18 CAR30683.1 - 1.2e-05 24.8 0.0 4.3e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 CAR30683.1 - 8.4e-05 22.1 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 LUC7 PF03194.10 CAR30684.1 - 1.1e-70 238.0 2.3 1.3e-70 237.8 1.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF948 PF06103.6 CAR30684.1 - 3.1 7.7 6.0 6.4 6.7 4.1 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 CAR30684.1 - 5.9 6.9 8.9 4.8 7.2 0.3 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ADH_zinc_N_2 PF13602.1 CAR30685.1 - 2.8e-12 47.6 0.0 6.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CAR30685.1 - 7.6e-08 31.9 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CAR30685.1 - 2e-05 24.2 0.0 6.3e-05 22.7 0.0 1.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.3 CAR30685.1 - 0.00073 18.7 0.0 0.00097 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Semialdhyde_dh PF01118.19 CAR30685.1 - 0.047 13.9 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 CAR30686.1 - 4.3e-12 47.0 0.0 8.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CAR30686.1 - 3e-07 30.0 0.0 7.4e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 CAR30686.1 - 1.1e-05 24.7 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ADH_N PF08240.7 CAR30686.1 - 4.1e-05 23.3 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CAR30686.1 - 0.0083 16.4 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Nup35_RRM PF05172.8 CAR30687.1 - 1.9e-31 107.8 0.0 3.3e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CAR30687.1 - 0.00087 19.0 0.0 0.0037 17.0 0.0 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2418 PF10332.4 CAR30688.1 - 1.9e-23 82.6 0.2 1.9e-23 82.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Calpain_III PF01067.17 CAR30689.1 - 1.2e-05 24.9 0.7 0.00037 20.1 0.2 3.0 2 1 0 2 2 2 1 Calpain large subunit, domain III ABC_tran PF00005.22 CAR30690.1 - 8.5e-58 194.5 0.0 3e-35 121.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CAR30690.1 - 1.8e-55 188.3 36.5 6.9e-34 117.5 6.6 3.9 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.14 CAR30690.1 - 1.3e-09 37.6 3.7 3.5e-06 26.4 0.4 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CAR30690.1 - 3.3e-09 37.3 4.7 0.00025 21.4 0.4 3.4 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 CAR30690.1 - 1.9e-08 34.6 10.7 3.9e-05 23.7 0.1 4.9 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.1 CAR30690.1 - 3.3e-07 29.7 0.4 0.0022 17.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CAR30690.1 - 4.3e-05 24.0 0.0 0.23 11.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 CAR30690.1 - 7.9e-05 23.4 0.0 0.12 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CAR30690.1 - 8.4e-05 21.8 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CAR30690.1 - 0.00013 21.8 0.0 0.018 15.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CAR30690.1 - 0.00052 20.1 0.1 1.9 8.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CAR30690.1 - 0.00055 19.9 1.2 0.26 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CAR30690.1 - 0.00062 19.2 0.0 0.62 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 CAR30690.1 - 0.00081 18.3 0.0 0.23 10.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 CAR30690.1 - 0.0016 18.1 0.6 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CAR30690.1 - 0.0032 17.7 0.1 3.9 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CAR30690.1 - 0.0037 16.3 0.1 1.4 7.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 CAR30690.1 - 0.0038 16.7 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 CAR30690.1 - 0.0052 16.3 0.0 4.5 6.7 0.0 3.2 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 CAR30690.1 - 0.0056 16.2 0.4 1.4 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CAR30690.1 - 0.0079 16.3 0.6 20 5.4 0.0 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CAR30690.1 - 0.012 15.0 0.0 0.93 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 CAR30690.1 - 0.026 13.9 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CAR30690.1 - 0.029 14.2 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 CAR30690.1 - 0.036 13.9 0.0 5.5 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CAR30690.1 - 0.11 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF87 PF01935.12 CAR30690.1 - 0.13 12.0 3.8 0.69 9.6 0.0 3.1 4 0 0 4 4 3 0 Domain of unknown function DUF87 AAA_30 PF13604.1 CAR30690.1 - 0.22 11.1 0.3 9.6 5.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain Cofilin_ADF PF00241.15 CAR30693.1 - 5.2e-42 142.7 0.6 5.7e-42 142.5 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.12 CAR30693.1 - 0.0054 16.7 0.4 0.01 15.8 0.1 1.5 2 0 0 2 2 2 1 Carbohydrate binding domain Phage_gp53 PF11246.3 CAR30693.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Base plate wedge protein 53 SET PF00856.23 CAR30694.1 - 1e-10 42.1 0.2 9.2e-10 39.0 0.0 2.5 2 1 0 2 2 2 1 SET domain FMN_dh PF01070.13 CAR30695.1 - 1.2e-113 379.6 0.0 1.4e-113 379.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 CAR30695.1 - 9.6e-06 24.8 0.3 0.012 14.7 0.1 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 CAR30695.1 - 1.3e-05 24.3 0.3 2.1e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CAR30695.1 - 0.00012 21.1 0.0 0.00017 20.6 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CAR30695.1 - 0.00053 19.2 0.1 0.00076 18.7 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 CAR30695.1 - 0.0052 16.0 0.2 0.03 13.5 0.1 2.2 2 1 1 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.16 CAR30695.1 - 0.046 12.6 0.1 0.094 11.6 0.1 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Zn_clus PF00172.13 CAR30696.1 - 1.2e-11 44.3 11.1 2.5e-11 43.3 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L29 PF00831.18 CAR30696.1 - 0.076 12.7 0.7 0.99 9.1 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1 PF07690.11 CAR30697.1 - 2.7e-16 59.2 46.0 4.2e-16 58.6 31.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CAR30697.1 - 0.0059 16.3 6.3 0.35 10.6 0.1 4.1 3 1 1 4 4 4 2 MFS_1 like family KRTAP PF11759.3 CAR30697.1 - 0.64 10.3 10.6 2.1 8.6 0.5 3.1 3 0 0 3 3 3 0 Keratin-associated matrix Mpv17_PMP22 PF04117.7 CAR30697.1 - 0.75 9.4 5.3 0.39 10.3 0.3 2.6 2 0 0 2 2 2 0 Mpv17 / PMP22 family MFS_1 PF07690.11 CAR30698.1 - 1.1e-36 126.3 37.1 7.8e-35 120.2 25.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 CAR30699.1 - 2.2e-07 30.6 14.9 6.9e-07 29.0 10.3 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C5HC2 PF02928.11 CAR30699.1 - 0.15 12.1 6.1 0.53 10.3 4.2 2.0 1 0 0 1 1 1 0 C5HC2 zinc finger DUF1451 PF07295.6 CAR30699.1 - 9.8 5.9 7.9 1.3 8.7 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Transp_cyt_pur PF02133.10 CAR30700.1 - 1.2e-78 264.6 32.9 1.5e-78 264.3 22.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Vel1p PF10339.4 CAR30701.1 - 1.4e-109 363.9 1.8 1.6e-109 363.7 1.2 1.0 1 0 0 1 1 1 1 Yeast-specific zinc responsive Flavodoxin_2 PF02525.12 CAR30702.1 - 2.5e-52 177.2 0.0 3.1e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CAR30702.1 - 3.9e-12 45.9 0.0 7.3e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CAR30702.1 - 1e-05 24.9 1.2 7.2e-05 22.1 0.5 2.4 2 1 0 2 2 2 1 Flavodoxin